gebhart/patrepeval huggingface dataset:
Experimental Characterization of Diversity Navigation (2013)

Wireless networks with navigation capability enable mobile devices to both communicate and determine their positions. Diversity navigation employing multiple sensing technologies can overcome the limitation of individual technologies, especially when operating in harsh environments such as indoors. To characterize the diversity of navigation systems in real environments, we performed an extensive measurement campaign, where data from heterogenous sensors were collected simultaneously. The performance of Bayesian navigation algorithms, relying on the particle filter implementation, is evaluated based on measured data from ultrawideband, ZigBee, and inertial sensors. This enables us to quantify the benefits of data fusion as well as the effect of statistical mobility models for real-time diversity navigation.
Plasmonic Quantum Cascade Laser Antenna (2007)

We demonstrate the plasmonic quantum cascade laser antenna, that can confine mid- infrared radiation beyond the diffraction limit, by integrating gold optical antennas on the laser facet.
ChemInform Abstract: Nickel‐Catalyzed Regioselective Hydroalkynylation of Styrenes: Improved Catalyst System, Reaction Scope, and Mechanism. (2009)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Deep learning for automated sleep staging using instantaneous heart rate (2020)

Clinical sleep evaluations currently require multimodal data collection and manual review by human experts, making them expensive and unsuitable for longer term studies. Sleep staging using cardiac rhythm is an active area of research because it can be measured much more easily using a wide variety of both medical and consumer-grade devices. In this study, we applied deep learning methods to create an algorithm for automated sleep stage scoring using the instantaneous heart rate (IHR) time series extracted from the electrocardiogram (ECG). We trained and validated an algorithm on over 10,000 nights of data from the Sleep Heart Health Study (SHHS) and Multi-Ethnic Study of Atherosclerosis (MESA). The algorithm has an overall performance of 0.77 accuracy and 0.66 kappa against the reference stages on a held-out portion of the SHHS dataset for classifying every 30 s of sleep into four classes: wake, light sleep, deep sleep, and rapid eye movement (REM). Moreover, we demonstrate that the algorithm generalizes well to an independent dataset of 993 subjects labeled by American Academy of Sleep Medicine (AASM) licensed clinical staff at Massachusetts General Hospital that was not used for training or validation. Finally, we demonstrate that the stages predicted by our algorithm can reproduce previous clinical studies correlating sleep stages with comorbidities such as sleep apnea and hypertension as well as demographics such as age and gender.
Pipeline embolization for definitive endoluminal reconstruction of blister-type carotid aneurysms after clip wrapping (2015)

A combined approach of acute surgical stabilization followed by definitive endovascular reconstruction may reduce hemorrhagic complications while improving long term treatment durability.
Design and implementation of overlaying multi-homing architecture (2004)

As a result of the vast Internet growth, a multi-homing technology is being extensively utilized to keep connectivity to important networks. However, the traditional multi-homing architecture severely impacts routing performance of the Internet making it non-scalable. Furthermore, although it can enhance reachability in case of connectivity anomalies, it can not be used to enhance utilization because it can not assign in-coming traffic to multiple links. We propose a new multi-homing architecture which is based on the overlay networking model, providing solutions to these problems. Our architecture improves scalability for increasing multi-homing users and realizes a dynamic and flexible line selection for in-coming traffic, while retaining the original advantage of the multi-homing scheme, which is continuous connectivity to the Internet. Of course, our proposed architecture can be applied not only to IPv4 networks but also to IPv6 networks.
Increased risk of acute myocardial infarction and elevated levels of C-reactive protein in carriersof the Thr-87 variant of the ATP receptor P2Y11 (2006)

The common Ala-87-Thr polymorphism of the P2Y11 receptor is associated with AMI and increased levels of C-reactive protein. We hypothesize that an inflammatory mechanism might be involved. The P2Y11 receptor is a promising new drug target in the prevention of AMI.
An Electronically Tunable Resonator for Noise Control (2001)

&lt;div class="htmlview paragraph"&gt;Many engineering systems create unwanted noise that can be reduced by the careful application of engineering noise controls. When this noise travels down tubes and pipes, a tuned resonator can be used to muffle noise escaping from the tube. The classical examples are automobile exhaust and ventilation system noise. In these cases where a narrow frequency band of noise exists, a traditional engineering control consists of adding a tuned Helmholtz resonator to reduce unwanted tonal noise by reflecting it back to the source (&lt;span class="xref"&gt;Temkin, 1981&lt;/span&gt;). As long as the frequency of the unwanted noise falls within the tuned resonator frequency range, the device is effective. However, if the frequency of the unwanted sound changes to a frequency that does not match the tuned resonator frequency, the device is no longer effective. Conventional resonators have fixed tuning and cannot effectively muffle tonal noise with time-varying frequency.&lt;/div&gt; &lt;div class="htmlview paragraph"&gt;The electronically tunable Semi-active Helmholtz Resonator (SHR) is a novel noise control device that includes a combination of conventional acoustic components combined with a hybrid control system. This device can be fully designed externally and attached to a primary acoustic system, such as a duct or pipe to reduce the transmission of tonal noise. It is adaptively tuned on-line to track a disturbance signal with slow time varying frequency. The paper presents a physical analytical model of the SHR, a power flow model that answers the question “Where does the power go?” and finally demonstrates the effectiveness of the device with experimental test results.&lt;/div&gt;
A detailed review on <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" altimg="si52.svg"> <mml:mrow> <mml:msub> <mml:mrow> <mml:mtext>CO</mml:mtext> </mml:mrow> <mml:mrow> <mml:mn>2</mml:mn> </mml:mrow> </mml:msub> </mml:mrow> </mml:math> two-phase ejector flow modeling (2020)

Ejector-equipped vapor-compression systems for refrigeration and cooling, relying solely on CO2 (R744) as a natural working fluid, are perceived to be an eco-friendly and highly efficient solution for many applications. However, the complexity of two-phase ejector flows makes it very challenging to find realiable and efficient ejector designs. Improved design methods are necessary in order to achieve higher performance in R744 units compared to the traditional compressor-based systems with refrigerants that put a high strain on the environment. Consequently, the development of advanced models and tools for an accurate design of the R744 ejectors has been a highly prioritized research topic. To the best of the authors’ knowledge, the current status of R744 ejector models and their limitations has not been thoroughly evaluated yet. To summarise the current state of the art and knowledge gaps, this work presents an exhaustive overview of the available numerical models applied to R744 two-phase ejectors, i.e. multiphase flow modeling, turbulence aspects, numerical solution methods, applications of models, to further encourage the adoption of R744 vapor-compression solutions. Finally, a thorough discussion of different focus points for future research as well as the main challenges in the field is presented.
Paracentesis is Associated with Reduced Mortality in Patients Hospitalized with Cirrhosis and Ascites (2014)

Diagnostic paracentesis is recommended for patients with cirrhosis admitted to the hospital for ascites or encephalopathy. However, it is not known if clinicians in the United States adhere to this recommendation; a relationship between paracentesis and clinical outcome has not been reported. We analyzed a US database to determine the frequency of paracentesis and its association with mortality.
Design considerations for asymmetric magnetically coupled resonators used in wireless power transfer applications (2013)

Magnetic resonance coupling is a widely used technique for wireless power transfer (WPT) in biomedical and consumer electronics applications. For specific applications, device size limits the overall size of the transmit and receive coils. In this work, design considerations for an asymmetrical 4-element WPT system are investigated. For either a target efficiency or a desired WPT range, the optimal coil parameters such as Q and coupling coefficient are defined and these design considerations are experimentally verified. The results can be used to design an optimal set of coils for various WPT applications.
ChemInform Abstract: Addition Reactions of C60 Leading to Fulleroprolines. (1994)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Integration of single-fiber reflectance spectroscopy into ultrasound-guided endoscopic lung cancer staging of mediastinal lymph nodes (2010)

We describe the incorporation of a single-fiber reflectance spectroscopy probe into the endoscopic ultrasound fine-needle aspiration (EUS-FNA) procedure utilized for lung cancer staging. A mathematical model is developed to extract information about the physiological and morphological properties of lymph tissue from single-fiber reflectance spectra, e.g., microvascular saturation, blood volume fraction, bilirubin concentration, average vessel diameter, and Mie slope. Model analysis of data from a clinical pilot study shows that the single-fiber reflectance measurement is capable of detecting differences in the physiology between normal and metastatic lymph nodes. Moreover, the clinical data show that probe manipulation within the lymph node can perturb the in vivo environment, a concern that must be carefully considered when developing a sampling strategy. The data show the feasibility of this novel technique; however, the potential clinical utility has yet to be determined.
Net benefit of oral anticoagulants in patients with atrial fibrillation and active cancer: a nationwide cohort study (2019)

Patients with AF and active cancer benefit from OAC treatment.
National Quality Assessment Evaluating Spironolactone Use During Hospitalization for Acute Myocardial Infarction (AMI) in China: China Patient‐centered Evaluation Assessment of Cardiac Events (PEACE)‐Retrospective AMI Study, 2001, 2006, and 2011 (2015)

URL: http://www.clinicaltrials.gov Unique identifier: NCT01624883.
Clinical aspects of neurodegenerative diseases – 15th HUPO BPP Workshop April 8–9, 2011, Bochum, Germany (2011)

The HUPO Brain Proteome Project (HUPO BPP) held its 15th workshop in Bochum, Germany, from April 8th to 9th, 2011 directly after the Proteomic Forum 2011 in Berlin. Like on every spring workshop, the focus was more on clinical aspects, so that especially clinicians participated in this workshop.
Rhodium‐Catalyzed Intramolecular C—H Insertion of α‐Aryl‐α‐diazo Ketones. (2007)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Simple and Fast Picomolar Detection of Ochratoxin A Using a Reusable Label Free Aptasensor Built with a Layer‐by‐layer Procedure (2017)

Abstract A label free impedimetric aptasensor for simple, fast and reusable picomolar detections of Ochratoxin A (OTA) in grape juices was designed. Two main factors were observed to affect the accurate detections of the toxin: i‐lateral interactions between self‐assembled aptamers ii‐ adsorption of large molecules present in complex matrixes like grape juices. Lateral interactions between aptamers were minimized by constructing the aptasensor in a Layer‐by‐Layer procedure. The interferences associated to the unspecific and irreversible adsorption of large molecules present in grape juice, were reduced by submitting samples to ultrafiltration prior to analysis. With this protocol, a 0.12 pM limit of detection and 0.24 pM limit of quantification in spiked grape juices were achieved after only 5–7 mins of interaction with the samples. The presented aptasensor can be recovered after a simple immersion in hot water (90 °C) for ten minutes.
High Accuracy In-Flight Wavelength Calibration of Imaging Spectrometry Data (1995)

Accurate wavelength calibration of imaging spectrometer data is essential if proper atmospheric transmission corrections are to be made to obtain apparent surface reflectance. Accuracies of 0.1 nm are necessary for a 10 nm-sampling instrument in order to match the slopes of the deep atmospheric water vapor features that dominate the 0.7-2.3 micrometer regions. The Airborne Visible/Infrared Imaging Spectrometer (AVIRIS) is calibrated in the laboratory to determine the wavelength position and full-width-half-maximum (FWHM) response for each of the 224 channels. The accuracies are limited by the quality of the monochromator used as a source. The accuracies vary from plus or minus to plus or minus 1.5 nm depending on the wavelength region, in general decreasing with increasing wavelength. Green et al. make corrections to the wavelength calibrations by using the known positions of 14 atmospheric absorption features throughout the 0.4-2.5 micrometer wavelength region. These features, having varying width and intensity, were matched to the MODTRAN model with a non-linear least squares fitting algorithm. A complete calibration was developed for all 224 channels by interpolation. Instrument calibration cannot be assumed to be stable to 0.1 nm over a flight season given the rigors of thermal cycling and launch and landing loads. The upcoming sensor HYDICE will require a means for in-flight spectral calibration of each scene because the calibration is both temperature and pressure sensitive. In addition, any sensor using a two-dimensional array has the potential for systematic wavelength shifts as a function of cross-track position, commonly called 'smile'. Therefore, a rapid means for calibrating complete images will be required. The following describes a method for determining instrument wavelength calibration using atmospheric absorption features that is efficient enough to be used for entire images on workstations. This study shows the effect of the surface reflectance on the calibration accuracy and the calibration history for the AVIRIS B spectrometer over the 1992 flight season.
A compact integrated plasmonic modulator (2009)

We describe an integrated plasmonic modulator with a compact and simple structure: current through a short and thin metallic layer, with plasmonic modes on both surfaces, can switch the light through a silicon waveguide underneath.
Response to Comment on "High Abrasion Resistance with Sparse Mineralization: Copper Biomineral in Worm Jaws" (2003)

Schofield and Nesson ( [1][1] ) express concern that the correlation between the element concentration in Glycera jaws and the mechanical properties of the jaw ( [2][2] ) may not reflect the correlation between atacamite mineral content and mechanical properties. They argue that there may be “
A biomechanical study comparing the compressive forces generated by a conventional 4.5 AO/ASIF cortical lag screw with a differentially pitched cortical compression screw. (2009)

The aim of this study was to compare the interfragmentary compression generated across a simulated femoral fracture model by a conventional 4.5 mm AO/ASIF cortical lag screw with a differentially pitched cortical compression screw. A 45-degree osteotomy was made in a whole bone composite femoral shaft, this was internally fixed with either a conventional 4.5 mm AO/ASIF cortical lag screw or the differentially pitched cortical screw and the compressive force generated at the fracture site measured on an Instron 8874 Axial/Torsion Servohydraulic Testing System. The mean interfragmentary compression generated by the differentially pitched screw was 81.4% of that generated by the 4.5 mm AO/ASIF cortical lag screw. The 4.5 mm AO/ASIF cortical screw produces a steep rise in compression per turn of the screw. The screw based on the differential pitch design creates a more gradual increase to peak compression. The resistance to torque was greater for the AO screw than for the differential pitch screw. Maximal interfragmentary compression is achieved within 4 180 degrees turns after the head engages the near cortex for the 4.5 mm AO/ASIF screw but required 5 180 degrees turns for the differentially pitched screw. Interfragmentary compression is achievable in cortical bone using differential pitch technology. A differentially pitched screw offers obvious advantages over a conventional screw allowing independent placement of lag screw and neutralisation plate, without needing additional exposure of the fracture site, limiting the insult to local fracture biology. It is proposed as an adjunct to osteosynthesis in long bone fractures.
Deciphering the genome structure of Theobroma cacao (W107) (2011)

Theobroma cacao L., is a diploid tree fruit species, originated from the South American rainforests, and constitutes an important source of incomes for farmers of tropical countries. We produced a high quality draft genome sequence corresponding to a 16,7X genome coverage of a criollo genotype. The assembly corresponds to 76% of the estimated genome size of the T. cacao genotype B97-61/B2 (430 Mbp). This assembly appears to cover a very large proportion of the euchromatin of the T. cacao genome, allowing to recover 97.8% of the unigene resource (38,737 unigenes assembled from 715,457 EST sequences) in the genome assembly. Annotations revealed 28,798 protein-coding genes among which 82% could be anchored in a high density genetic map. Only 20% of the genome consisted in transposable elements, a significantly lower percentage compared to other genome of similar size. This first cocoa genome sequence was the support for several genome analyses revealing specific extension of some gene families. The comparative mapping of genes involved in disease resistance and quality traits, localised in the genome sequence, and QTLs related to these traits highlighted several co-localisations between them and candidate genes potentially involved in useful cocoa trait variations. This genome sequence will facilitate a better understanding of trait elaboration and will accelerate T. cacao breeding through efficient marker assisted selection and exploitation of genetic resources. A genome browser allows to access freely to the cocoa sequence data at the following website : http://cocoagendb.cirad.fr. (Texte intégral)
P‐II‐03  Effect of Platelet Derived Wound Healing Factor (PDWHF) on the Angiogenesis in the Cases of Artificial Dermis Grafts (2004)

Aim: The effect of platelet derived wound healing factor (PDWHF) with or without cultured cells on angiogenesis in the cases of artificial dermis grafts was investigated. Methods: Wistar strain rats were used for this study. The PDWHF was prepared from platelets. The endothelial cells and fibroblasts were prepared from thoracic aorta and back skin respectively. Then 2 experimental models were designed. 1) Full‐thickness wounds were created on back of the animals. Artificial dermis (TERUDERMIS ® , TERUMO Co, Japan) were grafted to the wounds. 2) Femoral artery and vein were isolated as a vascular pedicle and wrapped with a folded sheet of the AD (1 × 2 cm). Prior to AD grafts, the AD were treated with the PDWHF and/or cultured cells. Results: The combination use of the PDWHF and cultured cells showed best angiogenesis in both experimental models. Conclusions: The result of the present study revealed that treatment with PDWHF combined with cultured cells accelerate the wound angiogenesis.
The anti-psychotic drug pimozide is a novel chemotherapeutic for breast cancer (2018)

Pimozide, an antipsychotic drug of the diphenylbutylpiperidine class, has been shown to suppress cell growth of breast cancer cells <i>in vitro</i>. In this study we further explore the inhibitory effects of this molecule in cancer cells. We found that Pimozide inhibited cell proliferation in a dose- and time-dependent manner in MDA-MB-231 breast cancer cells and A549 lung cancer cells. Furthermore, we found that Pimozide also promoted apoptosis as demonstrated by cell cycle arrest and induction of double-strand DNA breaks but did not result in any effect in the non-transformed MCF10A breast cell line. In order to shed new lights into the molecular pathways affected by Pimozide, we show that Pimozide downregulated RAN GTPase and AKT at both protein and mRNA levels and inhibited the AKT signaling pathway in MDA-MB-231 breast cancer cells. Pimozide also inhibited the epithelial mesenchymal transition and cell migration and downregulated the expression of MMPs. Administration of Pimozide showed a potent <i>in vivo</i> antitumor activity in MDA-MB-231 xenograft animal model and reduced the number of lung metastases by blocking vascular endothelial growth factor receptor 2. Furthermore, Pimozide inhibited myofibroblast formation as evaluated by the reduction in α-smooth muscle actin containing cells. Thus, Pimozide might inhibit tumor development by suppressing angiogenesis and by paracrine stimulation provided by host reactive stromal cells. These results demonstrate a novel <i>in vitro</i> and <i>in vivo</i> antitumor activity of Pimozide against breast and lung cancer cells and provide the proof of concept for a putative Pimozide as a novel approach for cancer therapy.