gebhart/patrepeval huggingface dataset:
Assessment of emissions of PM and NOx of sea going vessels by field measurements (2006)

The factors used to estimate emissions of sea going ships to air (so called emission factors) are based upon critical evaluation of the literature. Current estimates of emission factors of sea going ships are based upon a limited number of laboratory experiments and information on fuel usage and engine power. Especially emissions of nitrogen oxides (NOx) are reported in literature, measurements of particulate matter (PM2) are scarcer. It is important to realize that large variations in results are observed especially in emissions of particulate matter by engines using HFO (Heavy Fuel Oil). These are therefore rather uncertain. In the process of developing scenarios to improve local air quality and decrease atmospheric deposition accurate data on emissions are essential.
Early pulmonary involvement in systemic sclerosis assessed by technetium-99m-DTPA clearance rate. (1994)

These findings indicate that in SS asymptomatic patients may frequently present with abnormal 99mTc-DTPA clearance; 99mTc-DTPA lung scintigraphy may allow early detection of subclinical pulmonary involvement in SS.
Disproving the fusion hypothesis (2003)

Many prior efforts have been devoted to the basic idea that data fusion techniques can improve retrieval effectiveness. Recent work in the area suggests that many approaches, particularly multiple-evidence combinations, can be a successful means of improving the effectiveness of a system. Unfortunately, the conditions favorable to effectiveness improvements have not been made clear. We examine popular data fusion techniques designed to achieve improvements in effectiveness and clarify the conditions required for data fusion to show improvement. We demonstrate that for fusion to improve effectiveness, the result sets being fused must contain a significant number of unique relevant documents. Furthermore, we show that for this improvement to be visible, these unique relevant documents must be highly ranked. In addition, we present a comprehensive discussion on why previous assumptions about the effectiveness of multiple-evidence techniques are misleading. Detailed empirical results and analysis are provided to support our conclusions.
Survival of the posterior lamellar cornea graft keratocytes and endothelial cells cultivated in the modified corneal preservation media (2021)

Purpose. To study the survival of keratocytes and endothelial cells of a human donor cornea storage in the standard and the new media which was specifically designed for optimized cornea hydration. Material and methods. 2D cell cultures of keratocytes and endothelial cells obtained from the Eye tissue bank were used for culture in improved storage media over a period of 14 and 7 days subsequently. To confirm phenotype characteristics, the cells were stained by the following markers: for keratocytes – Lumikan, Keratocan, and α-smooth muscle actin; for endothelial cells – ZO-1 and Na/K-ATPase. The onset of apoptosis in cell culture of keratocytes were detected with Cytochrome C, BAX, and Caspase 3 and 8. Viability of cell cultures after the cultivation was carried out using a commercial set of "Live and Dead". Morphology of the endothelial cells was assessed using an electron scanning microscope. Results. It was shown that the 2D keratocyte culture cultured in the improved storage media expressed specific markers: Lumican, Keratocan, and did not express α-smooth muscle actin. There were no markers of apoptosis in the cell culture of keratocytes after 14 days of cultivation. Corneal endothelium cultured in the improved storage media expresses ZO-1, Na/K-ATPase and presented hexagonal cell shape morphology according to electron microscopy. Conclusion. The improved storage media allow to preserve the unique phenotype of keratocytes, with a slight decrease in proliferative cells activity during 14 days. The media maintain a viable and functional corneal endothelium for at least seven days of cultivation. Key words: cell culture; corneal endothelium; keratocyte; posterior lamellar graft, corneal storage media.
Impact of Channel Implant Variation on RTN and Flicker Noise (2020)

With different device doping options in fully depleted silicon-on-insulator (FDSOI) metaloxide semiconductor field effect transistor (MOSFET) channel and under different bias conditions the low frequency noise level can be manipulated and optimized. We demonstrated a noise level dependence on different channel device doping options and a lowering of gate input voltage (SVG) with different back gate voltages (Vb) in n-type metal-oxide semiconductor (NMOS) and p-type metal-oxide semiconductor (PMOS) structures.
ChemInform Abstract: Marine Bacteria. Part 42. Aqabamycins A‐G: Novel Nitro Maleimides from a Marine Vibrio Species. Part 2. Structure Elucidation. (2010)

ChemInformVolume 41, Issue 42 Natural Products ChemInform Abstract: Marine Bacteria. Part 42. Aqabamycins A-G: Novel Nitro Maleimides from a Marine Vibrio Species. Part 2. Structure Elucidation. Clarisse Blandine Fotso Fondja Yao, Inst. Org. Biomol. Chem., Georg-August-Univ., D-37077 Goettingen, GermanySearch for more papers by this authorWael Al Zereini, Inst. Org. Biomol. Chem., Georg-August-Univ., D-37077 Goettingen, GermanySearch for more papers by this authorSerge Fotso, Inst. Org. Biomol. Chem., Georg-August-Univ., D-37077 Goettingen, GermanySearch for more papers by this authorHeidrun Anke, Inst. Org. Biomol. Chem., Georg-August-Univ., D-37077 Goettingen, GermanySearch for more papers by this authorHartmut Laatsch, Inst. Org. Biomol. Chem., Georg-August-Univ., D-37077 Goettingen, GermanySearch for more papers by this author Clarisse Blandine Fotso Fondja Yao, Inst. Org. Biomol. Chem., Georg-August-Univ., D-37077 Goettingen, GermanySearch for more papers by this authorWael Al Zereini, Inst. Org. Biomol. Chem., Georg-August-Univ., D-37077 Goettingen, GermanySearch for more papers by this authorSerge Fotso, Inst. Org. Biomol. Chem., Georg-August-Univ., D-37077 Goettingen, GermanySearch for more papers by this authorHeidrun Anke, Inst. Org. Biomol. Chem., Georg-August-Univ., D-37077 Goettingen, GermanySearch for more papers by this authorHartmut Laatsch, Inst. Org. Biomol. Chem., Georg-August-Univ., D-37077 Goettingen, GermanySearch for more papers by this author First published: 23 September 2010 https://doi.org/10.1002/chin.201042218AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinked InRedditWechat No abstract is available for this article. Volume41, Issue42October 19, 2010 RelatedInformation
Phosphorylation of the WWOX Protein Regulates Its Interaction with p73 (2020)

We describe a molecular characterization of the interaction between the cancer-related proteins WWOX and p73. This interaction is mediated by the first of two WW domains (WW1) of WWOX and a PPXY-motif-containing region in p73. While phosphorylation of Tyr33 of WWOX and association with p73 are known to affect apoptotic activity, the quantitative effect of phosphorylation on this specific interaction is determined here for the first time. Using ITC and fluorescence anisotropy, we measured the binding affinity between WWOX domains and a p73 derived peptide, and showed that this interaction is regulated by Tyr phosphorylation of WW1. Chemical synthesis of the phosphorylated domains of WWOX revealed that the binding affinity of WWOX to p73 is decreased when WWOX is phosphorylated. This result suggests a fine-tuning of binding affinity in a differential, ligand-specific manner: the decrease in binding affinity of WWOX to p73 can free both partners to form new interactions.
Methodology for the analysis of the impact of the forging parameters on metallurgy and mechanical properties in case of solid electromagnetic manufactured parts (2016)

For electromagnetic applications the microstructure and the final mechanical state are key parameters. These can be obtained by a judicious choice of the material, a particular design like laminated steels but also through the determination and the mastering of the fabrication process. This present paper contains a brief introduction to electromagnetics and the qualification of a “good” electromagnetic quality. Then the article highlights, based on literature, first the influence of the process parameters on microstructure, mechanical state and secondly the impact these properties themselves on magnetic properties. Eventually, a methodology is proposed in order to predict the functional behavior of a part in its final system, taking into account its manufacturing process. The academic study case presented here can illustrate such a methodology. This kind of methodology includes in particular experimental tests, physical analysis and numerical modeling.
Structural investigation of polyaniline/Nylon 6 blends by small‐angle neutron scattering and small‐ and wide‐angle X‐ray scattering (1997)

The structure of blends of Nylon 6 with deuterated polyaniline emeraldine base (D-PANI-EB) and fully doped D-PANI salts (D-PANI-ES) formed from camphorsulfonic acid (CSA), methanesulfonic acid (MSA), or dodecyl benzenesulfonic acid (DBSA) were investigated by small-angle neutron (SANS) and X-ray scattering. The blends were formed from hexafluoro-2-propanol solutions and had volume fractions of 0.038, 0.20, and 0.40 for D-PANI/CSA, 0.20 and 0.40 for D-PANI/MSA, 0.24 and 0.44 for D-PANI/DBSA, and 0.07, 0.14, and 0.31 for D-PANI-EB. The SANS results are compared with a number of standard models for two-phase systems. No evidence was found for significant molecular mixing. In some cases the inverse power law model is in reasonable agreement with observations, and in the case of the lowest concentration of D-PANI/CSA there is an indication of mass fractal structure. This was not found at the higher concentrations. The results establish that the blends with the smaller more polar dopants CSA and MSA behave similarly and are unlike either the D-PANI/DBSA blends or those with D-PANI-EB. There is evidence that the simple picture of two pure phases is inadequate for these materials. With the exception of the D-PANI/DBSA blend which has a relatively low scattering contrast, the results indicate that the lower limit of volume fraction for application of SANS is a few percent D-PANI-ES in Nylon 6. X-ray scattering was used to demonstrate the presence of Nylon 6 lamellae and residual peaks attributable to the pure components. © 1997 John Wiley & Sons, Inc. J Polym Sci B: Polym Phys 35: 2765–2774, 1997
Figure S1 from Distinct Transcriptional Programming Drive Response to MAPK Inhibition in &lt;i&gt;BRAF&lt;/i&gt;&lt;sup&gt;V600&lt;/sup&gt;-Mutant Melanoma Patient-Derived Xenografts (2023)

&lt;p&gt;Response to encorafenib and binimetinib of BRAFV600 mutant melanoma PDX models.&lt;/p&gt;
Human papillomavirus-related cell cycle markers can predict survival outcomes following a transoral lateral oropharyngectomy for tonsillar squamous cell carcinoma (2014)

HPV-related cell cycle markers may also be good indicators for predicting survival after TLO for TSCC. The de-escalation TLO surgery approach would be more effective if performed under the stringent guidance of these markers.
Changes in the Composition of the Photosynthetic Apparatus in the Galactolipid-Deficient dgd1 Mutant of Arabidopsis thaliana (1997)

The glycerolipid digalactosyl diacylglycerol (DGDG) is exclusively associated with photosynthetic membranes and thus may play a role in the proper assembly and maintenance of the photosynthetic apparatus. Here we employ a genetic approach based on the dgd1 mutant of Arabidopsis thaliana to investigate the function of DGDG in thylakoid membranes. The primary defect in the genetically well-characterized dgd1 mutant resulted in a 90% reduction of the DGDG content. The mutant showed a decreased photosystem II (PSII) to photosystem I ratio. In vivo room- and low-temperature (77 K) chlorophyll fluorescence measurements with thylakoid preparations are in agreement with a drastically altered excitation energy allocation to the reaction centers. Quantification of pigment-binding apoproteins and pigments supports an altered stoichiometry of individual pigment-protein complexes in the mutant. Most strikingly, an increase in the amount of peripheral light-harvesting complexes of PSII relative to the inner antenna complexes and the PSII reaction center/core complexes was observed. Regardless of the severe alterations in thylakoid organization, photosynthetic oxygen evolution was virtually not compromised in dgd1 mutant leaves.
Synthesis, Characterizations of Superparamagnetic Fe<sub>3</sub>O<sub>4</sub>–Ag Hybrid Nanoparticles and Their Application for Highly Effective Bacteria Inactivation (2016)

In recent years, outbreaks of infectious diseases caused by pathogenic micro-organisms pose a serious threat to public health. In this work, Fe3O4-Ag hybrid nanoparticles were synthesized by simple chemistry method and these prepared nanoparticles were used to investigate their antibacterial properties and mechanism against methicilline-resistant Staphylococcus aureus (MRSA) pathogen. The formation of dimer-like nanostructure of Fe3O4-Ag hybrid NPs was confirmed by X-ray diffraction and High-resolution Transmission Electron Microscopy. Our biological analysis revealed that the Fe3O4-Ag hybrid NPs showed more noticeable bactericidal activity than that of plain Fe3O4 NPs and Ag-NPs. We suggest that the enhancement in bactericidal activity of Fe3O4-Ag hybrid NPs might be likely from main factors such as: (i) enhanced surface area property of hybrid nanoparticles; (ii) the high catalytic activity of Ag-NPs with good dispersion and aggregation stability due to the iron oxide magnetic carrier, and (iii) large direct physical contacts between the bacterial cell membrane and the hybrid nanoparticles. The superparamagnetic hybrid nanoparticles of iron oxide magnetic nanoparticles decorated with silver nanoparticles can be a potential candidate to effectively treat infectious MRSA pathogen with recyclable capability, targeted bactericidal delivery and minimum release into environment.
Planar in-hand manipulation via motion cones (2019)

In this article, we present the mechanics and algorithms to compute the set of feasible motions of an object pushed in a plane. This set is known as the motion cone and was previously described for non-prehensile manipulation tasks in the horizontal plane. We generalize its construction to a broader set of planar tasks, such as those where external forces including gravity influence the dynamics of pushing, or prehensile tasks, where there are complex frictional interactions between the gripper, object, and pusher. We show that the motion cone is defined by a set of low-curvature surfaces and approximate it by a polyhedral cone. We verify its validity with thousands of pushing experiments recorded with a motion tracking system. Motion cones abstract the algebra involved in the dynamics of frictional pushing and can be used for simulation, planning, and control. In this article, we demonstrate their use for the dynamic propagation step in a sampling-based planning algorithm. By constraining the planner to explore only through the interior of motion cones, we obtain manipulation strategies that are robust against bounded uncertainties in the frictional parameters of the system. Our planner generates in-hand manipulation trajectories that involve sequences of continuous pushes, from different sides of the object when necessary, with 5–1,000 times speed improvements to equivalent algorithms.
Evaluation of peptide/metal ion interactions by UV laser desorption time‐of‐flight mass spectrometry (1991)

A relatively recent method developed to determine the molecular weights of intact peptides and proteins, matrix-assisted UV laser desorption time-of-flight mass spectrometry (LDTOF-MS), has been evaluated as a new means to investigate the metal ion-binding properties of model synthetic peptides. A contiguous sequence of 25 residues on the surface of the 74 kDa human plasma metal-binding transport protein histidine-rich glycoprotein (HRG) has been identified as a bioactive metal-binding domain. The peptide, (GHHPH)5G, was synthesized and evaluated by LDTOF-MS before and after the addition of Cu(II) in solution with 2,5-dihydroxybenzoic acid as the matrix. In the absence of added Cu(II), the major protonated molecular ion (M + H)+ was observed to have a mass equal to its calculated mass (2904.0 Da). In the presence of Cu(II), however, five additional peaks were observed at mass increments of approximately 63.9 Da. The maximum Cu(II)-binding capacity observed for the 26-residue peptide (5 g-atoms/mol) suggested that up to 1 Cu(II) may be bound per 5-residue internal repeat unit (GHHPH) within this peptide; several other monovalent and divalent metal cations were not bound under identical conditions of analysis. The Cu(II)-binding stoichiometry was verified by spectrophotometric titration and by frontal analyses of the immobilized peptide with a solution of Cu(II) ions. These results demonstrate the ability to verify directly the solution-phase binding capacity of metal-binding peptides by LDTOF-MS.
Hip arthroscopy: surgical approach, positioning, and distraction. (2003)

The hip is the most deeply recessed joint in the body making it difficult to access arthroscopically. However, for the patient with a symptomatic loose body or labral tear open techniques are less advantageous. It is for this reason that, however difficult, minimally-invasive approaches to the hip have been developed. Meticulous attention to proper positioning and portal placement is paramount for safe and successful arthroscopy of the hip. The current authors will review the seminal features of positioning and minimally-invasive surgical approaches to the hip.
Thirty years of fast-tracking chemical reactions with microwaves: Aspirin case (2017)

This paper compares empirical chemical kinetic equations for salicylic acid acylation obtained under 2.45 GHz electromagnetic radiation with conventional electric heating. Results show changes in the activation energy value and in reactions orders, which indicate an alteration of the reaction mechanism. This mechanism alteration is accepted as the cause for microwave enhancement of this reaction. A new concept of microwave irradiated chemical reactor used in these experiments is described.
Taxotere and vincristine inhibit the secretion of the angiogenesis inducing vascular endothelial growth factor (VEGF) by wild-type and drug-resistant human leukemia T-cell lines. (2001)

Recent studies have shown that angiogenesis, which is induced by VEGF, may be involved in the pathogenesis of hematopoietic malignancies. A human leukemia model consisting of T-lymphoblastic CEM/0, 7 monoclonal refractory clones resistant to both cytosine arabinoside (ara-C) and L-asparaginase (ASNase), Jurkat/E6-1 and U937, representing the leukemic blasts from relapsed patients with leukemias was investigated for secretion of VEGF before and after treatment with various agents. The T-lymphoblastic cell line, Jurkat/E6-1, was used as the negative control, which has been characterized as not expressing mRNA nor the VEGF protein, and did not secrete VEGF. With no treatment, U937, the positive control, secreted the highest VEGF concentration of 1612.7 pg/ml. The CEM/O wild type cell line and 5 other drug-resistant clones secreted VEGF at levels ranging from 180.9 to 414.2 pg/ml. Two CEM drug-resistant clones, CEM/ara-C/G/ASNase-0.5-1 and CEM/ara-C/G/ASNase-1-1, lacked VEGF production. Docetaxel (Taxotere, TXR), Vincristine (VCR), ASNase, and the Fit-1/Fc chimera, a specific inhibitor of VEGF-dependent human umbilical vein endothelial cell (HUVEC) proliferation, were tested for inhibition of VEGF secretion. Treatment of the leukemic cell lines with 2 microg/ml Flt-1/Fc chimera for 24 hours completely inhibited VEGF secretion to the detection limit of the assay (<10pg/ml). After 24 hours incubation with Flt-1/Fc chimera, the leukemic cells appeared to be undergoing apoptosis, based on microphotography examination, suggesting that VEGF could be used in an autocrine loop to promote cell survival by the leukemic cells. Treatment with 0.5, 1, and 2 microg/ml Flt-1/FC chimera for 48 hours demonstrated a 15-25% growth inhibition by MTT assay. Strong inhibition of VEGF secretion in the culture media was observed after 10 microM TXR or 0.1 microM VCR for 24 hours in the wild-type and drug-resistant clones, except CEM/ara-C/I, in comparison with controls. In contrast, treatment with 1 IU/ml ASNase, a specific T-cell protein inhibitor, in 5 cell lines for 24 hours demonstrated no inhibition of VEGF in CEM/0 3 drug-resistant clones and the myeloid U937 line. We conclude that the leukemia cell lines actively secrete VEGF, in vitro. TXR and VCR, but not ASNase, strongly inhibit the VEGF production, suggesting that inhibition of this growth factor may be a mechanism of antileukemic activity. Moreover, the leukemic cell lines examined here may constitute a useful model to study antiangiogenic drugs, alone or in combination with established drug regimens used against refractory leukemias.
Structure Science in Bi, Pb-3d Transition Metal Perovskites (2007)

The interplays between crystal structures and physical properties in BiCoO3, PbVO3 and BiNiO3 are investigated. It is found that the t2g1 and t2g4eg2 electronic configurations of V4+ and Co3+ ions are the origin of the large tetragonal distortions in BiCoO3 and PbVO3. High pressure neutron diffraction measurements and Bond valence sum calculations on BiNiO3 with unusual oxidation state of Bi3+0.5Bi5+0.5Ni2+O3 show that the pressure-induced melting of the charge disproportionated state leads to a simultaneous charge transfer from Ni to Bi, so that the high pressure phase is metallic Bi3+Ni3+O3.
A Webcam-Based Interface Which Makes Arrangements of Characters to Anchor Texts (2009)

It is necessary for an interface to have a rapid response in order to realize a comfortable application for the user. We have proposed a real-time camera-based character recognition method, and we think that there is a possibility to realize a new interactive interface with it. In this paper, we demonstrate a system which recognizes characters captured with a webcam and offers related information.
The Chemistry and Biology of Bactobolin: A 10-Year Collaboration with Natural Product Chemist Extraordinaire Jon Clardy (2020)

Bactobolin is a hybrid natural product with potent cytotoxic activity. Its production from <i>Burkholderia thailandensis</i> was reported as part of a collaboration between the Greenberg and Clardy laboratories in 2010. The collaboration sparked a series of studies leading to the discovery of new analogues and associated structure-activity relationships, the identification of the bactobolin biosynthetic gene cluster and assembly of its unusual amino acid building block, the molecular target of and resistance to the antibiotic, and finally an X-ray crystal structure of the ribosome-bactobolin complex. Herein, we review the collaborations that led to our current understanding of the chemistry and biology of bactobolin.
Mycobacterium celatum sp. nov. (1993)

Microbiology Society journals contain high-quality research papers and topical review articles. We are a not-for-profit publisher and we support and invest in the microbiology community, to the benefit of everyone. This supports our principal goal to develop, expand and strengthen the networks available to our members so that they can generate new knowledge about microbes and ensure that it is shared with other communities.
PERFORMANCE ANALYSIS OF TEXTURE SIMILARITY METRICS IN HEVC INTRA PREDICTION (2015)

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