gebhart/patrepeval huggingface dataset:
Wireless Communication Links with Fading (2014)

This chapter familiarizes the reader with the basic propagation characteristics that describe various wireless communication channels, such as terrestrial, atmospheric, and ionospheric from very high frequencies (VHF) to the X-band. It focuses on the well-known standards in wireless communication for the prediction of path losses and fading effects of any radio signal in various communication links. The frequency band is a main characteristic for predicting the effectiveness of radio communication links. The chapter focuses on the type of noises, which exists in a complete communication system. In a wireless channel, specifically, the noise sources can be subdivided into additive (or white) and multiplicative effects. The chapter discusses the new possibilities that can be obtained using adaptive or smart antenna systems that are employed to reduce interference and decrease the bit error rate (BER).
A coded generalization of selective repeat ARQ (2015)

Reducing the in-order delivery, or playback, delay of reliable transport layer protocols over error prone networks can significantly improve application layer performance. This is especially true for applications that have time sensitive constraints such as streaming services. We explore the benefits of a coded generalization of selective repeat ARQ for minimizing the in-order delivery delay. An analysis of the delay's first two moments is provided so that we can determine when and how much redundancy should be added to meet a user's requirements. Numerical results help show the gains over selective repeat ARQ, as well as the trade-offs between meeting the user's delay constraints and the costs inflicted on the achievable rate. Finally, the analysis is compared with experimental results to help illustrate how our work can be used to help inform system decisions.
Effect of peptides bearing nuclear localization signals on therapeutic ultrasound mediated gene delivery (2008)

This study suggests that CPP-NLS peptides may be used for condensing pDNA and bringing it into the cell cytoplasm, but their ability to mediate nuclear import of pDNA is insignificant.
Elastin fibers and the diagnosis of bacterial pneumonia in the adult respiratory distress syndrome (1995)

Elastin fiber preparations are not specific for diagnosing bacterial pneumonia in patients with ARDS.
Crystal electric field excitations in the quantum spin liquid candidate <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:msub><mml:mi>NaErS</mml:mi><mml:mn>2</mml:mn></mml:msub></mml:math> (2020)

The delafossite family of compounds with a triangular lattice of rare earth ions has been recently proposed as a candidate host for quantum spin liquid (QSL) states. To realize QSLs, the crystal electric field (CEF) ground state of the rare earth ions should be composed of a doublet that allows sizable quantum tunneling, but until now the knowledge on CEF states in the delafossite compounds is still limited. Here we employ inelastic neutron scattering (INS) to study the CEF transitions in a powder sample of the delafossite ${\mathrm{NaErS}}_{2}$, where the large total angular momentum $J=15/2$ of the ${\mathrm{Er}}^{3+}$ ions and the resulting plethora of CEF transitions enable an accurate fit of the CEF parameters. Our study reveals nearly isotropic spins with large ${J}_{z}=\ifmmode\pm\else\textpm\fi{}1/2$ components for the ${\mathrm{Er}}^{3+}$ CEF ground states, which might facilitate the development of a QSL state. The scaling of the obtained CEF Hamiltonian to different rare earth ions suggests that sizable ${J}_{z}=\ifmmode\pm\else\textpm\fi{}1/2$ components are generally present in the CEF ground states, supporting the ternary sulfide delafossites as potential QSL hosts.
Relavant field trial of a photonics-based RF scanning receiver for electronic support measures (2016)

We present the field-trial results of a photonics-based radio-frequency scanning receiver demonstrator for electronic support measures (ESM). Typical complex electromagnetic operative scenarios are emulated and correctly acquired, confirming the previously tested laboratory performance of the proposed system, and its promising suitability for actual ESM applications.
The impact of direct-to-consumer personal genomic testing on perceived risk of breast, prostate, colorectal, and lung cancer: findings from the PGen study (2015)

We have quantified the effect on consumer risk perception of returning genetic-based cancer risk information directly to consumers without clinician mediation. Provided via PGT, this information has a measurable but modest effect on perceived cancer risk, and one that is in some cases modified by consumers' non-genetic risk context. Our observations of modest marginal effect sizes, infrequent extreme changes in perceived risk, and a pattern of diminishing impact with time, suggest that the ability of PGT to effect changes to cancer screening and prevention behaviors may be limited by relatively small changes to perceived risk.
Cytokine and chemokine gene expression in patients with clinically suspect arthralgia; a longitudinal study during progression to inflammatory arthritis or non-progression (2022)

Abstract Background Autoantibody-responses rise years before onset of inflammatory arthritis (IA) and are stable during transitioning from clinically suspect arthralgia (CSA) to IA. Cytokine and chemokine levels can also rise years before IA-onset, but the course after CSA-onset is unknown. To better understand the processes in this symptomatic at-risk phase, we studied the course of cytokine, chemokine and related receptors gene expression in CSA-patients during progression to IA, and in CSA-patients who ultimately did not develop IA. Differential expressed genes between ACPA-positive and ACPA-negative CSA-patients who developed IA were also explored. Methods Whole blood RNA expression of 37 inflammatory cytokines/chemokines/related receptors was determined by dual-color reverse-transcription multiplex ligation-dependent probe amplification, in paired samples of CSA-patients at CSA-onset and either at IA-development or after 24-months without IA-development. ACPA-positive and ACPA-negative CSA-patients developing IA were compared at CSA-onset and during progression to IA. GEE-models tested changes over time. A false discovery rate approach was applied to correct for multiple testing. Results None of the cytokines/chemokine genes significantly changed in expression between CSA-onset and IA-development. In CSA-patients without IA development, G-CSF expression decreased (p=0.001), whereas CCR6 and TNIP expression increased (p&lt;0.001 and p=0.002, respectively) over a 2-year period. Expression levels in ACPA-positive and ACPA-negative CSA-patients who developed IA were similar. Conclusion Whole blood gene expression of cytokines, chemokines and related receptors did not change significantly from CSA to IA-development. This suggests that changes in expression of these molecules occurred preceding CSA-onset and may not relate to the final hit of developing chronic arthritis. Observed changes in CSA-patients not developing IA can provide clues for processes related to resolution.
Energy-Efficient Hydrogenated Zinc Oxide Nanoflakes for High-Performance Self-Powered Ultraviolet Photodetector (2016)

Light absorption efficiency and doping induced charge carrier density play a vital role in self-powered optoelectronic devices. Unique vanadium-doped zinc oxide nanoflake array (VZnO NFs) is fabricated for self-powered ultraviolet (UV) photodetection. The light harvesting efficiency drastically improved from 84% in ZnO NRs to 98% in VZnO NFs. Moreover, the hydrogenation of as-synthesized VZnO (H:VZnO) NFs displayed an outstanding increase in response current as compared to pristine structures. The H:VZnO NFs device presents an extraordinary photoelastic behavior with faster photodetection speed in the order of ms under a low UV illumination signal. Excellent responsivity and external quantum efficiency with larger value of specific detectivity of H:VZnO NFs device promises an outstanding sensitivity for UV signal and self-powered high-performance visible-blind photodetector.
Methodology to design mobile-based camera lenses using freeform surfaces (2021)

Freeform technology is one of the most promising solutions to enhance the performance of optical systems. Aiming to demonstrate the freedom and flexibility of optical system design, several challenging design examples using freeform surface are presented, including two wide-angle camera lenses adopting even and odd pedal polynomial formulations for symmetric optical surface description, and an anamorphic cinema lens employing non-rotationally symmetric surfaces for capturing a wider aspect ratio and offering a 1.33X squeeze factor on a 4:3 sensor size. Methods and constraints for designing and optimizing the optical systems are discussed. The optical performances of these design examples are analyzed. The results verify the practicability and effectiveness of the proposed formulations and design strategies in the field of freeform imaging optical design.
Deactivation of a mixed oxide catalyst of Mo–V–Te–Nb–O composition in the reaction of oxidative ethane dehydrogenation (2016)

The operational stability of a mixed oxide catalyst of Mo–V–Te–Nb–O composition in the oxidative dehydrogenation of ethane (ratio of C2H6: O2 = 3: 1) is studied in a flow reactor at temperatures of 340–400°C, a pressure of 1 atm, and a WHSV of the feed mixture of 800 h−1. It is found that the selectivity toward ethylene is 98% at 340°C, but the conversion of ethane at this temperature is only 6%; when the temperature is raised to 400°C, the conversion of ethane is increased to 37%, while the selectivity toward ethylene is reduced to 85%. Using physical and chemical means (XPS, SEM), it is found that the lack of oxidant in the reaction mixture leads to irreversible changes in the catalyst, i.e., reduced selectivity and activity. Raising the reaction temperature to 400°C allows the reduction of tellurium by ethane, from the +6 oxidation state to the zerovalent state, with its subsequent sublimation and the destruction of the catalytically active and selective phase; in its characteristics, the catalyst becomes similar to the Mo–V–Nb–O system containing no tellurium.
Targeting KDM4B that coactivates c-Myc-regulated metabolism to suppress tumor growth in castration-resistant prostate cancer (2021)

<b>Rationale:</b> The progression of prostate cancer (PCa) to castration-resistant PCa (CRPC) despite continuous androgen deprivation therapy is a major clinical challenge. Over 90% of patients with CRPC exhibit sustained androgen receptor (AR) signaling. KDM4B that removes the repressive mark H3K9me3/2 is a transcriptional activator of AR and has been implicated in the development of CRPC. However, the mechanisms of KDM4B involvement in CRPC remain largely unknown. Here, we sought to demonstrate the molecular pathway mediated by KDM4B in CRPC and to provide proof-of-concept evidence that KDM4B is a potential CRPC target. <b>Methods:</b> CRPC cells (C4-2B or CWR22Rv1) depleted with KDM4B followed by cell proliferation (<i>in vitro</i> and xenograft), microarray, qRT-PCR, Seahorse Flux, and metabolomic analyses were employed to identify the expression and metabolic profiles mediated by KDM4B. Immunoprecipitation was used to determine the KDM4B-c-Myc interaction region. Reporter activity assay and ChIP analysis were used to characterize the KDM4B-c-Myc complex-mediated mechanistic actions. The clinical relevance between KDM4B and c-Myc was determined using UCSC Xena analysis and immunohistochemistry. <b>Results:</b> We showed that KDM4B knockdown impaired CRPC proliferation, switched Warburg to OXPHOS metabolism, and suppressed gene expressions including those targeted by c-Myc. We further demonstrated that KDM4B physically interacted with c-Myc and they were co-recruited to the c-Myc-binding sequence on the promoters of metabolic genes (<i>LDHA</i>, <i>ENO1</i>, and <i>PFK</i>). Importantly, KDM4B and c-Myc synergistically promoted the transactivation of the <i>LDHA</i> promoter in a demethylase-dependent manner. We also provided evidence that KDM4B and c-Myc are co-expressed in PCa tissue and that high expression of both is associated with worse clinical outcome. <b>Conclusions:</b> KDM4B partners with c-Myc and serves as a coactivator of c-Myc to directly enhance c-Myc-mediated metabolism, hence promoting CRPC progression. Targeting KDM4B is thus an alternative therapeutic strategy for advanced prostate cancers driven by c-Myc and AR.
Use of Spin Echo Magic Angle Spinning <sup>1</sup>H NMR in Reaction Monitoring in Combinatorial Organic Synthesis (1996)

ADVERTISEMENT RETURN TO ISSUEPREVAddition/CorrectionNEXTUse of Spin Echo Magic Angle Spinning 1H NMR in Reaction Monitoring in Combinatorial Organic SynthesisRavi S. Garigipati, Bruce Adams, Jerry L. Adams, and Susanta K. SarkarCite this: J. Org. Chem. 1996, 61, 15, 5190Publication Date (Web):July 26, 1996Publication History Published online26 July 1996Published inissue 1 January 1996https://pubs.acs.org/doi/10.1021/jo964011fhttps://doi.org/10.1021/jo964011fcorrectionACS PublicationsCopyright © 1996 American Chemical Society. This publication is available under these Terms of Use. Request reuse permissions This publication is free to access through this site. Learn MoreArticle Views328Altmetric-Citations10LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Get e-Alertsclose Get e-Alerts
Passive immunization to reduce Campylobacter jejuni colonization and transmission in broiler chickens (2014)

Campylobacter jejuni is the most common cause of bacterium-mediated diarrheal disease in humans worldwide. Poultry products are considered the most important source of C. jejuni infections in humans but to date no effective strategy exists to eradicate this zoonotic pathogen from poultry production. Here, the potential use of passive immunization to reduce Campylobacter colonization in broiler chicks was examined. For this purpose, laying hens were immunized with either a whole-cell lysate or the hydrophobic protein fraction of C. jejuni and their eggs were collected. In vitro tests validated the induction of specific ImmunoglobulinY (IgY) against C. jejuni in the immunized hens' egg yolks, in particular. In seeder experiments, preventive administration of hyperimmune egg yolk significantly (P < 0.01) reduced bacterial counts of seeder animals three days after oral inoculation with approximately 104 cfu C. jejuni, compared with control birds. Moreover, transmission to non-seeder birds was dramatically reduced (hydrophobic protein fraction) or even completely prevented (whole-cell lysate). Purified IgY promoted bacterial binding to chicken intestinal mucus, suggesting enhanced mucosal clearance in vivo. Western blot analysis in combination with mass spectrometry after two-dimensional gel-electrophoresis revealed immunodominant antigens of C. jejuni that are involved in a variety of cell functions, including chemotaxis and adhesion. Some of these (AtpA, EF-Tu, GroEL and CtpA) are highly conserved proteins and could be promising targets for the development of subunit vaccines.
Biocontrol of rats in an urban environment in Southeast Asia using <i>Sarcocystis singaporensis</i> (2019)

S. singaporensis may be used successfully as tactical biocontrol agent for culling of rats in urban environments. We propose additional components of a long-term rodent management strategy for the town, without which the impact of culling campaigns would be limited. © 2019 Society of Chemical Industry.
Optimizing CIGB-300 intralesional delivery in locally advanced cervical cancer (2015)

Intralesional injections of 70 mg CIGB-300 in two sites (0.5 ml per injection) and this treatment plan are recommended to be evaluated in phase 2 studies.
Hydrogen Production from Water in a Solid Oxide Electrolysis Cell: Effect of Ni Doping on Lanthanum Strontium Ferrite Perovskite Cathodes (2019)

High-temperature water electrolysis in a solid oxide electrolysis cell (SOEC) can be an efficient way of producing hydrogen, especially if it can be coupled with a renewable energy source. In this study, the performance of a nickel-doped, A-site deficient lanthanum strontium ferrite (La0.7Sr0.2FeO3) was investigated as an SOEC cathode. Electrolysis of H2O was carried out using a cathode stream containing 3% H2O/He at 800 °C and at various current densities. It was found that La0.7Sr0.2FeO3 has a lower Faradaic efficiency for hydrogen production than the Ni-doped cathode for which the efficiency reaches 100%. XRD shows that the undoped sample forms a nonconducting La2O3 secondary phase which affects the electrochemical performance negatively. On the nickel-doped sample, however, a B-site metal phase and a Ruddlesden–Popper phase with mixed electronic and ionic conductivity are formed, which enhances the electrochemical performance of the cathode.
ChemInform Abstract: N‐Formyl Hydroxylamine Containing Dipeptides: Generation of a New Class of Vasopeptidase Inhibitors. (2000)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Fabrication of microlens and microlens array using CO<sub>2</sub> laser and characterization of formation process (2003)

Microlenses and microlens arrays were formed directly on a surface of a glass plate by using a CO2 laser. This method has the merit of complete dry processing. We discuss about the formation mechanism and process through the characterization of the composition and refractive index distribution within the microlens.
PM322 Fasting Glucose Independent of 2-Hour Glucose in Oral Glucose Tolerance Test Predicts Chronic Kidney Disease Progression in a Chinese Community-Based Population Without Chronic Kidney Disease at Baseline (2016)

Activated carbons from peach stones and waste polyolefin wax were prepared and tested as a host matrix of nanodispersed zinc ferrite. Nitrogen physisorption, Boehm method, XRD, TPR with hydrogen, FTIR, UV–Vis and Moessbauer spectroscopy were applied to investigate the activated carbon characteristics and the state of loaded on it metal oxide particles. The higher microporosity and lower surface functionality, typical of activated carbon from waste biomass, facilitated the formation of more finely dispersed, located into the micropores iron and zinc oxide nanoparticles. This promoted formation of Zn rich ferrite phase which ensures high catalytic activity in methanol decomposition.
Bioisosteric OH- to SH-replacement changes the antioxidant profile of ferulic acid (2019)

We report the synthesis of 4-thioferulic acid (TFA), a new ferulic acid (FA) derivative, and highlight the differences between the two compounds concerning rate and mechanism of radical scavenging activity, redox potential, acidity of the phenol/thiophenol moieties, cytotoxicity in differentiated SH-SY5Y cells, and neuroprotection against hydrogen peroxide (H<sub>2</sub>O<sub>2</sub>) and tert-butyl hydroperoxide (t-BHP) in the same cellular model.
The acute diuretic effect of an ethanolic fraction of Phyllanthus amarus (Euphorbiaceae) in rats involves prostaglandins (2018)

Altogether, this study has shown that EFPA promotes a significant urinary excretion of water and Na<sup>+</sup>, confirming its diuretic activity. Moreover, the increased diuresis could be attributed, at least in part, to the involvement of prostaglandins.
Synthesis and antiviral evaluation of 2′,3′-dideoxy-2′,3′-difluoro-D-arabinofuranosyl 2,6-disubstituted purine nucleosides (2015)

The synthesis of new 2,6-disubstituted purine 2',3'-dideoxy-2',3'-difluoro-D-arabino nucleosides is reported. Their ability to block HIV and HCV replication along with their cytotoxicity toward Huh-7 cells, human lymphocyte, CEM and Vero cells was also assessed. Among them, β-2,6-diaminopurine nucleoside <b>25</b> and guanosine derivative <b>27</b> demonstrate potent anti-HIV-1 activity (EC<sub>50</sub> = 0.56 and 0.65 μM; EC<sub>90</sub> = 4.2 and 3.1 μM) while displaying only moderate cytotoxicity in primary human lymphocytes.
Probing the Local Conformation within π‐Conjugated One‐dimensional Supramolecular Stacks using Frequency Modulation Atomic Force Microscopy (2009)

Frequency-modulation atomic force microscopy is used to investigate the local conformation within 1D stacks obtained by the self-assembly of π-conjugated molecules from solution. The structural parameters extracted from the experimental data can be interpreted in terms of local molecular conformation, by comparison with models obtained by molecular mechanics and dynamics simulations.
Two-photon absorption (2015)

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