gebhart/patrepeval huggingface dataset:
Surface finish and optical quality of CaF 2 for UV lithography applications (1998)

CaF<SUB>2</SUB> has received increasing attention as a promising substrate for coatings in the VUV range. Optimization of the optical properties of these optical components requires the study of basic characteristics of the coated and uncoated CaF<SUB>2</SUB> substrates such as surface roughness, optical performance, absorption and scatter losses, and laser induced damage threshold. The investigations reveal the influence of different substrate polishing grades on the quality of the coated components.
The focused abdominal sonography for trauma examination can reliably identify patients with significant intra-abdominal hemorrhage in life-threatening pelvic fractures (2018)

Therapeutic, level IV.
Is it possible to increase<i>n</i>-3 fatty acid content of meat without affecting its technological and/or sensory quality and the growing performance of chickens? (2015)

The aim of this study was to increase the content of n-3 fatty acids (FA) of meat without affecting its sensory and/or technological properties or the growth performance of chickens reared under standard conditions. Male chickens, Ross 308, were distributed into 5 groups corresponding to 5 different diets for the growing and finishing periods: control (T), containing extruded linseeds exhibiting high concentration of fibre (ELHF), extruded linseeds exhibiting low concentration of fibre (ELLF), microalgae, or an association of 75% ELLF and 25% MA (ELLF+MA). The diet containing microalgae induced a decrease in feed consumption without affecting growth rate. Chickens exhibited a lower feed conversion ratio than the other groups for the growing and finishing periods but also the whole rearing period. The use of linseeds in diets had no effect on the growth performance of chickens in comparison to the control group. The dietary enrichment with n-3 FA had few effects on carcass composition or the ultimate pH and colour of breast meat. The microalgae increased the meat susceptibility to oxidation. The lipid content of breast meat was not affected by the diets. The breast meat of chickens fed on diets containing linseeds and/or microalgae had greater n-3 FA content (2.4 to 3.9 times higher than group T). The linseeds and microalgae mainly increased the contents in linolenic acid and long chain n-3 FA, respectively. Dietary enrichment with n-3 FA had no effect on the sensory quality of fillets whereas the thighs of the MA group exhibited the lowest score for the flavour "chicken" and the greatest score for the flavour "abnormal" corresponding to a fish flavour.
Direct Intrinsics: Learning Albedo-Shading Decomposition by\n Convolutional Regression (2015)

We introduce a new approach to intrinsic image decomposition, the task of\ndecomposing a single image into albedo and shading components. Our strategy,\nwhich we term direct intrinsics, is to learn a convolutional neural network\n(CNN) that directly predicts output albedo and shading channels from an input\nRGB image patch. Direct intrinsics is a departure from classical techniques for\nintrinsic image decomposition, which typically rely on physically-motivated\npriors and graph-based inference algorithms.\n The large-scale synthetic ground-truth of the MPI Sintel dataset plays a key\nrole in training direct intrinsics. We demonstrate results on both the\nsynthetic images of Sintel and the real images of the classic MIT intrinsic\nimage dataset. On Sintel, direct intrinsics, using only RGB input, outperforms\nall prior work, including methods that rely on RGB+Depth input. Direct\nintrinsics also generalizes across modalities; it produces quite reasonable\ndecompositions on the real images of the MIT dataset. Our results indicate that\nthe marriage of CNNs with synthetic training data may be a powerful new\ntechnique for tackling classic problems in computer vision.\n
Hemodynamic characteristics in microcirculatory blood channels during early tumor growth. (1979)

Abstract Red blood cell (RBC) velocity was determined in the microcirculation of the BA 1112 rat sarcoma and in regions located outside the tumor (repairing tissue), which were used as a control and were assumed to be representative for the inflammatory-reparative reaction of a healing wound. Studies were carried out in modified Algire chamber preparations utilizing television techniques in situ during a period of 18 days. RBC velocity in repairing tissue was of the order of 0.80 ± 0.15 (S.E.) mm/sec in terminal arterioles, 0.2 ± 0.09 mm/sec in postcapillary venules, and 0.2 ± 0.1 mm/sec in collecting venules and remained constant during the observation period. By comparison, RBC velocity in terminal arterioles of the tumor tissue increased from 0.72 ± 0.08 mm/sec to 0.95 ± 0.09 mm/sec and decreased slightly in postcapillary and collecting venules. Vasomotion in terminal arterioles of the malignant tissue portion could be demonstrated only until Day 22 after implantation. Since vasomotion was observed only during the initial phase of tumor growth and the arteriolar RBC velocity increased during the same period, our findings indicate that blood is supplied to mesenchymal tumor by means of dilated arterioles. Our observations are related to control measurements in adjacent repairing tissue, which like tumor tissue exhibits continuous cellular replication. In this tissue, the RBC velocity of postcapillary and collecting venules remained constant. By comparison, RBC velocity decreased in venular outflow vessels of the tumor, suggesting that venous drainage is facilitated during progressive spread of the BA 1112 sarcoma.
Interaction of reactively sputtered TaOx thin films with In-Sn-O thin films and properties of TaOx thin films (1992)

The interaction of reactively sputtered TaOx films with In-Sn-O (ITO) films was investigated. Phenomena observed in the TaOx/ITO layer structure after a postannealing were studied. These phenomena were: a rise in electrical resistance of the ITO films and a change in color of the layer from transparent to yellowish. Monitoring the gases evolved from the TaOx films during the heating under vacuum showed that incorporation of water into the TaOx films takes place. Evolution of this water from the TaOx films started at around 350 °C, peaked at around 500 °C, and was largely complete at around 650 °C. It was found that the occurrence of the phenomena described above appeared at precisely the temperature at which water was evolved from the TaOx films. It was concluded that the water component incorporated into the TaOx films was the origin of both phenomena. Water present in the conditions under which discharge deposition takes place would be the cause of that incorporation.
Multiomic signals associated with maternal epidemiological factors contributing to preterm birth in low- and middle-income countries (2023)

Preterm birth (PTB) is the leading cause of death in children under five, yet comprehensive studies are hindered by its multiple complex etiologies. Epidemiological associations between PTB and maternal characteristics have been previously described. This work used multiomic profiling and multivariate modeling to investigate the biological signatures of these characteristics. Maternal covariates were collected during pregnancy from 13,841 pregnant women across five sites. Plasma samples from 231 participants were analyzed to generate proteomic, metabolomic, and lipidomic datasets. Machine learning models showed robust performance for the prediction of PTB (AUROC = 0.70), time-to-delivery (<i>r</i> = 0.65), maternal age (<i>r</i> = 0.59), gravidity (<i>r</i> = 0.56), and BMI (<i>r</i> = 0.81). Time-to-delivery biological correlates included fetal-associated proteins (e.g., ALPP, AFP, and PGF) and immune proteins (e.g., PD-L1, CCL28, and LIFR). Maternal age negatively correlated with collagen COL9A1, gravidity with endothelial NOS and inflammatory chemokine CXCL13, and BMI with leptin and structural protein FABP4. These results provide an integrated view of epidemiological factors associated with PTB and identify biological signatures of clinical covariates affecting this disease.
Wavelength Conversion in Modulated Dual-Mode Resonators and its Equivalence to a Linear Filter Model (2014)

We present a resonant modulation scheme that enables efficient wavelength conversion. The system maps onto linear filter equations that provide straightforward analysis and optimized design. Efficiencies of silicon carrier-plasma modulator implementations are estimated.
Lactic Acid Fermentation of Pomegranate Juice as a Tool to Improve Antioxidant Activity (2019)

An increasing consumer demand for pomegranate has been globally observed, mainly thanks to the scientific evidence related to its functional and health-promoting features. Pomegranate fruits from twenty accessions identified in Southeastern Italy were characterized according to morphological and chemical features. Juices extracted from pomegranate fruits were fermented with selected <i>Lactobacillus plantarum</i> PU1 and the antioxidant activity investigated. Whey was added to juices to promote the microbial growth. Fermentation led to the increase of the radical scavenging activity (up to 40%) and significant inhibition of the linoleic acid peroxidation. The three fermented juices showing the highest antioxidant activity, and the corresponding unfermented controls, were further characterized. In detail, the cytotoxicity and the protective role toward artificially induced oxidative stress were determined on murine fibroblasts Balb 3T3 through the determination of the viability and the intracellular ROS (reactive oxygen species) scavenging activity (RSA). RSA reached values of <i>ca.</i> 70% in fermented juices, being <i>ca.</i> 40% higher than the unfermented and control samples. Phenols compounds of the pomegranate juices obtained from accessions "Bitonto Piscina," "Sanrà nero," and "Wonderful (reference cultivar) were analyzed through ultrahigh pressure liquid chromatography coupled with mass spectrometry, showing that a marked increase (up to 60%) of the ellagitannins derivatives occurred during fermentation. Sensory analysis showed suitability of the fermented juices to be used as beverage and food ingredient.
How To RAMI 4.0: Towards An Agent-based Information Management Architecture (2019)

With the latest advances in digitalization and Industry 4.0, the manufacturing industry is collecting more and more production data. However, with the increasing interconnection of machines, not only the volume but also the variety of data is being expanded. The data life cycles of collection, processing, combining, analyzing and feeding new findings back into sources are becoming increasingly challenging for data scientists to complete. Reference architectures such as the RAMI 4.0 provide conceptual guidelines to address these problems. In this paper, we focus on the implementation of an agent-based architecture that is in line with RAMI 4.0. This architecture implements the guidelines provided by RAMI 4.0 by applying modern approaches from the areas of data lake based data acquisition, semantic description, look up and processing as well as information utilization.
Cerebral arteriovenous malformation in a neonate: treatment by embolisation. (1987)

A neonate with an aneurysm of the vein of Galen was treated by embolisation using Giant-urco coils. Doppler ultrasound examination showed that blood flow in the internal carotid artery decreased while that in the pericallosal artery increased after occlusion, suggesting a 'steal phenomenon' with blood directed preferentially towards the aneurysm.
Design and Synthesis of 4-(2-Pyrrolyl)-4-phenylheptane Derivatives as Estrogen Receptor Antagonists (2019)

Materials and MethodsAll chemicals were purchased from Sigma-Aldrich, FUJIFILM Wako Pure Chemicals, and Tokyo Chemical Industry and were used without further purification.TLC analysis was conducted using Merck silica gel 60 F254 pre-coated plates and visualized using a 254 nm/365 nm UV lamp, and iodine stain.Column chromatography was performed using silica gel (spherical, neutral) purchased from Kanto Chemical. 1 H and 13 C NMR spectra were recorded on a JEOL ECZ600 spectrometer, and measurements were carried out in CDCl 3 with 0.03% tetramethylsilane or MeOD-d 4 .High-resolution mass spectra were measured using a Shimadzu IT-TOF MS equipped with an electrospray ionization source.
Sp1 phosphorylation regulates inducible expression of platelet-derived growth factor B-chain gene via atypical protein kinase C-zeta (2001)

Platelet-derived growth factor (PDGF) is a broadly expressed mitogenic and chemotactic factor with diverse roles in a number of physiologic and pathologic settings. The zinc finger transcription factors Sp1, Sp3 and Egr-1 bind to overlapping elements in the proximal PDGF B-chain promoter and activate transcription of this gene. The anthracycline nogalamycin has previously been reported to inhibit the capacity of Egr-1 to bind DNA in vitro. Here we used electrophoretic mobility shift assays to show that nogalamycin added to cells in culture did not alter the interaction of Egr-1 with the PDGF-B promoter. Instead, it enhanced the capacity of Sp1 to bind DNA. Nogalamycin increased PDGF-B mRNA expression at the level of transcription, which was abrogated by mutation of the Sp1 binding site in the PDGF-B promoter or overexpression of mutant Sp1. Rather than increasing total levels of Sp1, nogalamycin altered the phosphorylation state of the transcription factor. Overexpression of dominant-negative PKC-zeta blocked nogalamycin-inducible Sp1 phosphorylation and PDGF-B promoter-dependent expression. Nogalamycin stimulated the phosphorylation of PKC-zeta (on residue Thr(410)). These findings demonstrate for the first time that PKC-zeta and Sp1 phosphorylation mediate the inducible expression of this growth factor.
Semi-analytical full-wave model of OCT-scan formation for various degrees of OCT-beam focusing with implication of motion of scatterers (2020)

Numerical beam refocusing in OCT is used to increase lateral resolution in the out-of-focus areas for strongly focused beams. However, this approach is based on overlapping lateral scanning in the assumption of the same scatterers positions. In the presence of scatterer motions the numerical refocusing approach can fail. It limit the applicability of the numerical refocusing approach to such based on scatterer motion evaluation modalities as angiography and elastopgraphy. Due to hard controlling phantom experiments we evaluate the influence of motion of scatterers on numerical beam refocusing on the base of numerical simulated OCT scans. The motions of the scatterers are well controlled in the numerical model and its effect on the numerical refocusing approach can be quantified. For this study, a full-wave model for simulating images in spectral-domain optical coherence tomography (OCT) with rigorous accounting for the beam-focusing effects is used.
Machine learning classification of disrotatory IRC and conrotatory non-IRC trajectory motion for cyclopropyl radical ring opening (2021)

Quasiclassical trajectory analysis is now a standard tool to analyze non-minimum energy pathway motion of organic reactions. However, due to the large amount of information associated with trajectories, quantitative analysis of the dynamic origin of reaction selectivity is complex. For the electrocyclic ring opening of cyclopropyl radical, more than 4000 trajectories were run showing that allyl radicals are formed through a mixture of disrotatory intrinsic reaction coordinate (IRC) motion as well as conrotatory non-IRC motion. Geometric, vibrational mode, and atomic velocity transition-state features from these trajectories were used for supervised machine learning analysis with classification algorithms. Accuracy >80% with a random forest model enabled quantitative and qualitative assessment of transition-state trajectory features controlling disrotatory IRC versus conrotatory non-IRC motion. This analysis revealed that there are two key vibrational modes where their directional combination provides prediction of IRC versus non-IRC motion.
Poly(ethylene glycol) stabilized Co nanoparticles as highly active and selective catalysts for the Pauson–Khand reaction (2007)

PEG-stabilized cobalt nanoparticles were prepared by thermal decomoposition of [Co2(CO)8] in PEG and were shown to be highly active and selective catalysts, for intra- and intermolecular Pauson-Khand reactions (PKR), in organic solvents or aqueous media.
<i>TRIM5</i> allelic polymorphism in macaque species/populations of different geographic origins: its impact on SIV vaccine studies (2011)

Tripartite motif 5α (TRIM5α) is a potent antiretroviral immune factor present in the cytoplasm of cells of most tissue types. The rhesus macaque TRIM5 gene has been shown to display polymorphism, with different variants being divided into three groups (TRIM5(TFP), TRIM5(Q), and TRIM5(CypA)), which may have divergent retroviral effects on infection. Along with rhesus macaques, cynomolgus macaques are also used in simian immunodeficiency virus (SIV) infection studies. As a consequence, TRIM5 genotyping of these animals will contribute to interpreting the outcome of such studies. The present communication covers Burmese, Chinese, and a large cohort of Indian-origin rhesus macaques, and describes the first large cohort study on TRIM5 polymorphism in outbred cynomolgus macaques. We demonstrate the presence of the TRIM5(TFP) group in cynomolgus macaques. In addition, we have re-evaluated historical samples of rhesus macaques challenged with SIV(mac251), a virus that has been reported to be partially suppressed by particular rhesus macaque TRIM5 variants.
New polysilicon sensor and actuator technology for the development of a thermal platform (2009)

This paper reports on a generic approach for the development of polysilicon diodes on glass wafers for thermal sensing and control applications. The capabilities of polysilicon diodes as thermal sensors are demonstrated on glass wafers with good thermal sensitivities about 40 mV/degC. A simple experimental set-up has been developed to evaluate the potentialities of these devices in microfluidics operating conditions. First encouraging results of temperature detection are presented.
Machines as an assistants for humans' creativity: A conceptual model (2017)

Creativity and imagination are the most interesting and peculiar of all properties of human consciousness that are not yet fully understandable for scientists. “Could creativity or imagination ever be defined?”, “Will humans lose their creativity in the rapid development of technology?” or “Could machines ever be creative and how this will effect on humanity?”. In this paper, we will address these questions from the point of view of different disciplines. We will describe and analyze state-of-the-art literature of existing methodologies and techniques that somehow describe the basics of creativity. At the end, we will come up with the new concept of Creativity Assistant System (CAS) that should be able to replicate “creativity”. We will provide the mathematical model of the CAS concept that is based on the motivation, preference and past experience of specific user along with available knowledge for further developing her/his “psychological creativity”.
Immunobiological properties and chemical compositions of cellular and extracellular endotoxic substances from Actinobacillus actinomycetemcomitans. (1986)

Actinobacillus actinomycetemcomitans ATCC 29523株, Y4株, SUNYaB67株を用い, リポ多糖体 (LPS), 全菌体抽出物, 菌体外産物を調製し, 免疫生物学的活性に関し詳細に検索した。実験にはマウスリンパ系細胞を用い, マイトジェン活性, 多クローン性B細胞活性化作用 (PBA活性), アジュバント活性を測定した。また, マウス腹腔マクロファージを用い, インターロイキン1産生誘導能を調べた。その結果, LPSはマイトジェン活性, PBA活性, アジュバント活性を有していた。一方, 全菌体抽出物と菌体外産物はマイトジェン活性を示したが, 両標品ともPBA活性は弱くアジュバント活性は認められなかった。IL-1産生誘導能は全標品に認められた。以上, LPSはB細胞の分裂を惹起し, 抗体産生細胞を誘導し, 免疫増強アジュバント活性を有していた。歯周炎に特徴的な形質細胞の浸潤増殖に本菌のLPSが深く関与している可能性が示唆された。
Thermodynamics of Silicon-Hydroxide Formation in H2O Containing Atmospheres (2001)

The formation of volatile silicon-hydroxide species from SiO2 in water containing atmospheres has been identified as a potentially important mode of degradation of Si-based ceramics. Availability of thermodynamic data for these species is a major problem. This study is part of an ongoing effort to obtain reliable, experimentally determined thermodynamic data for these species. The transpiration method was used to measure the pressure of Si-containing vapor in equilibrium with SiO2 (cristobalite) and Ar + H2O(g) with various mole fractions of water vapor, X(sub H2O), at temperatures ranging from 1000 to 1780 K. Enthalpies and entropies for the reaction, SiO2(s) + 2H2O(g) = Si(OH)4(g), were obtained, at X(sub H2O) = 0.15 and 0.37, from the variation of lnK with 1/T according to the 'second law method'. The following data were obtained: delta(H)deg = 52.9 +/- 3.7 kJ/mole and delta(S)deg = -68.6 +/- 2.5 J/mole K at an average temperature of 1550 K, and delta(H)deg = 52.5+/-2.0 kJ/mole and delta(S)deg= -69.7 +/- 1.5 J/moleK at an average temperature of 1384 K, for X(sub H2O)= 0.15 and 0.37, respectively. These data agree with results from the literature obtained at an average temperature of 1600 K, and strongly suggest Si(OH)4(g) is the dominant vapor species. Contradictory results were obtained with the determination of the dependence of Si-containing vapor pressure on the partial pressure of water vapor at 1187 and 1722 K. These results suggested the Si-containing vapor could be a mixture of Si(OH)4 + SiO(OH)2. Further pressure dependent studies are in progress to resolve these issues.
Graphene-Assisted Solution Growth of Vertically Oriented Organic Semiconducting Single Crystals (2015)

Vertically oriented structures of single crystalline conductors and semiconductors are of great technological importance due to their directional charge carrier transport, high device density, and interesting optical properties. However, creating such architectures for organic electronic materials remains challenging. Here, we report a facile, controllable route for producing oriented vertical arrays of single crystalline conjugated molecules using graphene as the guiding substrate. The arrays exhibit uniform morphological and crystallographic orientations. Using an oligoaniline as an example, we demonstrate this method to be highly versatile in controlling the nucleation densities, crystal sizes, and orientations. Charge carriers are shown to travel most efficiently along the vertical interfacial stacking direction with a conductivity of 12.3 S/cm in individual crystals, the highest reported to date for an aniline oligomer. These crystal arrays can be readily patterned and their current harnessed collectively over large areas, illustrating the promise for both micro- and macroscopic device applications.
Maintaining Chaos in High Dimensions (1998)

In dynamical systems, as a parameter is varied past a critical value, a chaotic attractor may be destroyed by a crisis. This attractor is replaced by a chaotic transient, which eventually leads to a different attractor. We present a method for maintaining chaotic dynamics after the crisis. The model, formulated for arbitrary dimensions, directs the phase space trajectory toward a target region near the periodic saddle orbit that mediates the crisis. It is used to maintain chaos numerically in the Ikeda map and experimentally in a magnetoelastic ribbon.
Predictors of incipient dysfunction of all cardiac chambers after treatment of metastatic renal cell carcinoma by tyrosine kinase inhibitors (2016)

The right heart exhibited greater strain changes than the left heart after TKI treatment. The implications of these findings and their potential significance warrant further work.