gebhart/patrepeval huggingface dataset:
Experimental Characterization and Modeling of Capillary-Pumped Thin-Film Evaporation From Micropillar Wicks (2016)

Generation of concentrated heat load in confined spaces in integrated circuits and advanced microprocessors has presented a thermal management challenge for the semiconductor industry. Compared to state-of-the-art single phase cooling strategies, phase-change based approaches are promising for cooling the next generation microelectronic devices. In particular, thin-film evaporation from engineered surfaces has received significant attention in the last few decades as a potential candidate since it enables passive transport of the working fluid via capillarity in addition to increasing the evaporation area via extending the liquid meniscus and three-phase contact line. Thin-film evaporation, however, is coupled with nucleate boiling making experimental characterization as well as modeling of the fluidic and thermal transport a challenging task for thermal engineers. Furthermore, quantifying the relative contributions of nucleate boiling and thin-film evaporation from the experimentally reported heat fluxes has been difficult. Unlike previous studies, our work experimentally characterizes thin-film evaporation in the absence of nucleate boiling from arrays of silicon micropillars. In particular, we characterize the capillary-limit where the microstructured surface dries out due to liquid starvation when the capillary pressure that is generated due to the meniscus shape cannot overcome the viscous losses within the micropillar wick. We modeled the fluidic and thermal transport of the evaporating meniscus by solving the coupled heat and mass transfer equations. Compared to experiments, our model predicts the dryout heat flux with ±20% accuracy. The insights gained from this study provide a suitable platform to design and optimize micropillar wicks for phase-change based thermal management devices such as heat pipes and vapor chambers.
Development of a triple NanoPCR method for feline calicivirus, feline panleukopenia syndrome virus, and feline herpesvirus type I virus (2022)

In this report, it is the first time that NanoPCR assays are applied in the detection of FCV, FPV, and FHV-1 as well. This sensitive and specific NanoPCR assay can be widely used in clinical diagnosis and field monitoring of FCV, FPV, and FHV-1 infections.
Tissue Kallikrein Inhibits Retinal Neovascularization via the Cleavage of Vascular Endothelial Growth Factor-165 (2011)

These findings indicate that tissue kallikrein is partly involved in pathogenesis of proliferative diabetic retinopathy and may be a promising therapeutic agent that could cleave VEGF165 itself when administered by a peripheral route.
Increased plasma ghrelin following infliximab in Crohn’s disease (2008)

Infliximab increases circulating total ghrelin by 25% in CD and restores the postprandial response of acylated ghrelin to food intake. Acylated and de-sacyl ghrelin remain unchanged, suggesting that an alternate isoform could be affected by infliximab.
Efficient Regression of General-Activity Human Poses from Depth Images: Supplementary Material (2011)

mean average precision using grid search with a step size of 0.05m in the range [0.05, 0.60]m. Table 1 shows that depending on which error metric is used (i.e., does missing an occluded joint count as a false negative or not?), the optimized length thresholds are quite different. In the right column we see that when the model is penalized for missing occluded joints, it makes use of longer range votes to maximize mAP. In some cases, such as head, feet, and ankles, the difference is rather large. Intuitively this makes sense: occluded joints tend to be further away from visible depth pixels than non-occluded joints. This experiment used a forest trained on 30k images.
Molecular determination of perivesical and lymph node metastasis after radical cystectomy for urothelial carcinoma of the bladder. (2001)

This molecular assay aimed at assessing perivesical extension and lymph node status after radical cystectomy appears to identify patients that may harbor residual disease not appreciated by conventional histology. Larger studies with 5-7-year follow-up will be required to determine the prognostic significance of such molecular information.
Determining the Phenotypic Potential of Reconstructed Networks (2015)

How often have I said to you that when you have eliminated the impossible, whatever remains, however improbable, must be the truth? – Sherlock Holmes, A Study in Scarlet
Safety and Feasibility of Induction Immunosuppression When Driveline Infection Is an Indication for Cardiac Transplantation (2015)

In patients with active DLI, induction immunosuppression after OHT did not increase LOS, infections, or mortality after at least 30 months of follow-up and therefore it appears to be a safe and feasible therapeutic option.
Targets and Approaches for Cancer Drug Discovery (2005)

This chapter contains sections titled: Introduction Signal Transduction Targets Targeting Tumor Vasculature DNA Targets Antimitotics Promising New Targets Sources of Small-Molecule Drug Leads Resources for Drug Discovery References
Numeric reconstruction of a distribution of electrically active defects in PVDF from the thermoluminescence spectra (2003)

In the thermally stimulated luminescence spectrum of PVDF three peaks are found in the temperature range 120 K (/spl gamma/-peak), 190 K (/spl beta/-peak) and 320 K (/spl alpha/-peak). The use of numeric methods for experimental results development with the application of the regularization algorithms of Tikhonov (1986) and the method of varying the sample heating rate, allows one to define in a reliable way the parameters of the most probable activation energy and the effective frequency factor of electrically active defects for all relaxation processes in PVDF.
Immune Status of Infants Fed Soy-Based Formulas With or Without Added Nucleotides for 1 Year: Part 1: Vaccine Responses, and Morbidity (2002)

Background Immunologic development of soy-fed infants has not been extensively studied. Early studies of soy flour–based formulas showed decreased immunoglobulin production when soy protein intake was limited. However, there were no significant differences in rotavirus vaccine responses between breast-fed and soy protein isolate–based formula-fed infants. Nucleotides added to milk-based formula benefit infant immune status, but reports of the immunologic effects of adding nucleotides to soy-based formula are not available. This study evaluated immune status and morbidity of infants fed soy protein isolate formulas with and without added nucleotides for 1 year. Methods Newborn, term infants enrolled in a masked 12-month feeding trial were assigned randomly to groups fed soy formula with or without added nucleotides (n = 94, n = 92). A nonrandomized human milk/formula cohort (n = 81) was concurrently enrolled. Recommended immunizations were administered at 2, 4, and 6 months. Immune status was determined from antibody responses to Haemophilus influenzae type b, tetanus, diphtheria, and poliovirus vaccines at 6, 7, and 12 months. Parents and physicians reported morbidity data. Results All vaccine responses were within normal ranges. No response differences were observed between infants fed soy formula and those fed nucleotide-supplemented soy. However, antibody to H. influenzae type b at 7 and 12 months was higher in infants fed nucleotide-supplemented soy than in infants fed human milk/formula (P = 0.007, P = 0.008, respectively). Human milk/formula-fed infants had higher poliovirus neutralizing antibody at 12 months than did soy-fed infants (P = 0.016). Morbidity analyses showed that only physician-reported diarrhea was different among groups (groups fed human milk/formula had less diarrhea than did soy groups, P = 0.011). Conclusions Term infants fed soy protein isolate–based formulas have normal immune development as measured by antibody responses to childhood immunizations.
Local contractions regulate E-cadherin rigidity sensing (2022)

E-cadherin is a major cell-cell adhesion molecule involved in mechanotransduction at cell-cell contacts in tissues. Because epithelial cells respond to rigidity and tension in tissue through E-cadherin, there must be active processes that test and respond to the mechanical properties of these adhesive contacts. Using submicrometer, E-cadherin-coated polydimethylsiloxane pillars, we find that cells generate local contractions between E-cadherin adhesions and pull to a constant distance for a constant duration, irrespective of pillar rigidity. These cadherin contractions require nonmuscle myosin IIB, tropomyosin 2.1, α-catenin, and binding of vinculin to α-catenin. Cells spread to different areas on soft and rigid surfaces with contractions, but spread equally on soft and rigid without. We further observe that cadherin contractions enable cells to test myosin IIA-mediated tension of neighboring cells and sort out myosin IIA-depleted cells. Thus, we suggest that epithelial cells test and respond to the mechanical characteristics of neighboring cells through cadherin contractions.
End-of-life practices: Ensuring ‘quality of dying’ during withdrawal of life-sustaining measures (2016)

The majority of deaths on Dutch intensive care units (ICUs) occur after withdrawal of life-sustaining measures. While curative care centres on survival, end-of-life care focuses on ‘quality of dying’. In end-of-life care, evaluation of all interventions is made in terms of whether they contribute to the patient’s comfort. In general, adequate dosing of opioids and benzodiazepines can provide comfort. Contrary to popular belief, these medications do not hasten death. Pain, dyspnoea-associated distress, anxiety and excessive bronchopulmonary secretion should be routinely assessed, prevented and treated adequately. Withdrawal of lifesustaining measures can consist of withdrawal of mechanical ventilation and/or vasoactive medication; in case of the former, there is no ethical justification for a prolonged weaning process. Family-centred care and communication are essential in endof-life care and continue even after the patient’s death. End-oflife care should be a priority in each ICU to limit suffering and optimise quality of dying.
A Case of a Rare Association Between Right Thyroid Hemiagenesis, Lingual Thyroid, and Papillary Thyroid Cancer (2017)

Lingual thyroid and thyroid hemiagenesis are rare thyroid developmental abnormalities. These conditions can be present with other thyroid diseases, whether functional ones involving abnormal thyroid hormone levels, or structural ones such as presence of thyroid nodules, however the association with thyroid cancer and lingual thyroid or thyroid hemiagenesis is rare. In addition to that, when thyroid hemiagenesis is present, it is usually in the left lobe. We describe here a pregnant patient who presented with metastatic cervical nodes from thyroid cancer who was found on imaging to have right thyroid hemiagenesis. After she underwent an initial surgery for thyroid cancer and metastatic nodal disease, she was then later discovered to have a lingual thyroid. In this case we report this extremely rare combination and also discuss the potential implications of this association on the diagnosis and management of these patients particularly initial surgery and imaging studies needed for the thyroid cancer.
Kinetic Analysis of Co‐oxidation of Biomembrane Lipids Induced by Water‐Soluble Radicals (2016)

Abstract Experiments on the oxidation of the biomembrane lipids, cholesterol (ChH) and phospholipids (LH), induced by water‐soluble radicals were performed in three types of model liposome systems. To clarify mechanisms of sole LH and ChH oxidations and their co‐oxidation, these systems were prepared using oxidizable LH and non‐oxidizable ChH, non‐oxidizable LH and oxidizable ChH, and oxidizable LH and ChH. Experimental results showed that sole oxidation of LH or ChH in the lipid phase was induced by water‐soluble radicals and that ChH oxidation was strongly accelerated by LH oxidation. A kinetic model was constructed based on reaction mechanisms that considered mass transfer of water‐soluble radicals from the water to lipid phases, a series of sole oxidations of LH and ChH initiated by transferred radicals in the lipid phase, and accelerated reactions between LH and ChH. The resulting model quantitatively described sole LH and ChH oxidations and their co‐oxidation behaviors in liposome systems under various water‐soluble radical concentrations.
Construction and Validation of Multi-Coil Technology for Accessible Head-Only Scanner (2023)

As part of a multi-center effort to design and build an accessible 1.5 T head-only MRI scanner (NIH U01EB025153, PI M. Garwood), we designed and constructed a prototype multi-coil array fitting the limited available space and capable of generating linear and non-linear image encoding fields as well as strong concomitant localized B 0 shim fields. Here, we describe the construction process, and present system characteristics as well as experimental validation of its field generation capabilities utilizing a conventional 4 T MRI scanner.
Glucocorticoids induce focus formation and increase sarcoma viral expression in a mink cell line that contains a murine sarcoma viral genome (1978)

Dexamethasone (3 X 10(-10) to 3 X 10(-6) M) induced foci of morphologically transformed cells in a small proportion of a mink cell line that contains the Moloney murine sarcoma viral genome (S+L-). The induction was glucocorticoid specific, since other steroids with glucocorticoid activity (prednisolone, cortisol, and aldosterone) induced foci with an efficiency that paralleled their glucocorticoid activity, and steroids lacking glucocorticoid activity (17B-estradiol, testosterone, and progesterone) failed to induce foci. Viral antigen, as measured by specific immunofluorescence, was localized to the foci. The induction of foci by dexamethasone (3 X 10(-7)) was accompanied by an approximately 10-fold increase in intracellular Moloney murine sarcoma virus-specific RNA and viral p30 antigen. Removal of dexamethasone was followed by the disappearance of foci and a decrease in viral RNA and p30. In this cell system, therefore, glucocorticoids can affect the intracellular levels of type C viral RNA and protein.
A New Spectral-Based Approach To Query-By-Humming For Mp3 Songs Database (2007)

In this paper, we propose a new approach to query-by-humming, focusing on MP3 songs database. Since MP3 songs are much more difficult in melody representation than symbolic performance data, we adopt to extract feature descriptors from the vocal sounds part of the songs. Our approach is based on signal filtering, sub-band spectral processing, MDCT coefficients analysis and peak energy detection by ignorance of the background music as much as possible. Finally, we apply dual dynamic programming algorithm for feature similarity matching. Experiments will show us its online performance in precision and efficiency.
Identification of Language-Specific Brain Activity Using Magnetoencephalography (1998)

The purpose of the present investigation was to explore the ability of magnetoencephalography (MEG) to identify brain areas involved in language comprehension. Event-related magnetic fields (ERFs) were recorded from 7 right-handed adults with no history of neurological disorder or learning disability as they engaged in an auditory and a visual word-recognition task. A face-recognition task served as control. During the later portion of the ERFs, activity sources from both language tasks tended to overlap in temporal and temporo-parietal cortices. There was a clear preponderance of such sources in the left compared to the right hemisphere in all participants. These findings demonstrate that MEG is a promising tool for identifying brain regions involved in the analysis of linguistic stimuli, in addition to the initial encoding of stimulus features.
Figure S2 from EGFRvIII–Stat5 Signaling Enhances Glioblastoma Cell Migration and Survival (2023)

&lt;p&gt;Specificity of siRNAs targeting Stat isoforms in GBM cells&lt;/p&gt;
Analysis of multidimensional models of monolith catalysts for hybrid combustors (1995)

Abstract Distributed parameter models of the single channel of a monolith combustor have been derived from progressively simplified assumptions. Simulation results are compared to assess the importance of the different physicochemical phenomena occurring in the combustor and to identify the simplest adequate model. For typical operating conditions of the hybrid combustor (gas and wall temperature not exceeding 1,073 and 1,273 K, respectively, high flow rate and pressure, natural gas as fuel), the results show that variations of gas properties have to be considered while homogeneous combustion can be neglected. Assumption of the approximate radial profile of axial velocity with invariant parabolic shape, rather than the rigorous solution of momentum balance and the continuity equation, provides accurate results. Moreover, for simulation of ceramic monoliths, backward heat transmission by wall conduction can be neglected with a substantial saving of computational labor.
Recent Advances in Flexible Perovskite Solar Cells: Fabrication and Applications (2018)

Flexible perovskite solar cells have attracted widespread research effort because of their potential in portable electronics. The efficiency has exceeded 18 % owing to the high-quality perovskite film achieved by various low-temperature fabrication methods and matching of the interface and electrode materials. This Review focuses on recent progress in flexible perovskite solar cells concerning low-temperature fabrication methods to improve the properties of perovskite films, such as full coverage, uniform morphology, and good crystallinity; demonstrated interface layers used in flexible perovskite solar cells, considering key figures-of-merit such as high transmittance, high carrier mobility, suitable band gap, and easy fabrication via low-temperature methods; flexible transparent electrode materials developed to enhance the mechanical stability of the devices; mechanical and long-term environmental stability; an outlook of flexible perovskite solar cells in portable electronic devices; and perspectives of commercialization for flexible perovskite solar cells based on cost.
Improvement of dislocation density in thick CVD single crystal diamond films by coupling H<sub>2</sub>/O<sub>2</sub> plasma etching and chemo‐mechanical or ICP treatment of HPHT substrates (2014)

H 2 /O 2 plasma treatments offer advantages over other etching processes of diamond as a technique to prepare the substrate's surface prior to homoepitaxial CVD diamond growth particularly in the case of thick films. It allows removing surface defects induced by polishing, thus leading to an improved morphology and limiting the stress within the grown crystal. Nevertheless, this treatment induces surface roughness leading to dislocation formation when CVD growth is initiated. In this paper we combined H 2 /O 2 plasma etching with smoother surface treatment such as RIE‐ICP etching or Chemo‐Mechanical Polishing and we showed a significant reduction in dislocation density of the thick CVD epitaxial layers.
Insights into the biotechnology potential of Methanosarcina (2022)

Methanogens are anaerobic archaea which conserve energy by producing methane. Found in nearly every anaerobic environment on earth, methanogens serve important roles in ecology as key organisms of the global carbon cycle, and in industry as a source of renewable biofuels. Environmentally, methanogenic archaea play an essential role in the reintroducing unavailable carbon to the carbon cycle by anaerobically converting low-energy, terminal metabolic degradation products such as one and two-carbon molecules into methane which then returns to the aerobic portion of the carbon cycle. In industry, methanogens are commonly used as an inexpensive source of renewable biofuels as well as serving as a vital component in the treatment of wastewater though this is only the tip of the iceberg with respect to their metabolic potential. In this review we will discuss how the efficient central metabolism of methanoarchaea could be harnessed for future biotechnology applications.
Titanium Complexes of Oxacalix[3]arenes: Synthesis and Mechanistic Studies of their Dynamic Isomerization (1994)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTTitanium Complexes of Oxacalix[3]arenes: Synthesis and Mechanistic Studies of their Dynamic IsomerizationPhilip D. Hampton, Charles E. Daitch, Todd M. Alam, Zsolt Bencze, and Melanie RosayCite this: Inorg. Chem. 1994, 33, 21, 4750–4758Publication Date (Print):October 1, 1994Publication History Published online1 May 2002Published inissue 1 October 1994https://pubs.acs.org/doi/10.1021/ic00099a028https://doi.org/10.1021/ic00099a028research-articleACS PublicationsRequest reuse permissionsArticle Views95Altmetric-Citations22LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
STaRFlow: A SpatioTemporal Recurrent Cell for Lightweight Multi-Frame\n Optical Flow Estimation (2020)

We present a new lightweight CNN-based algorithm for multi-frame optical flow\nestimation. Our solution introduces a double recurrence over spatial scale and\ntime through repeated use of a generic "STaR" (SpatioTemporal Recurrent) cell.\nIt includes (i) a temporal recurrence based on conveying learned features\nrather than optical flow estimates; (ii) an occlusion detection process which\nis coupled with optical flow estimation and therefore uses a very limited\nnumber of extra parameters. The resulting STaRFlow algorithm gives\nstate-of-the-art performances on MPI Sintel and Kitti2015 and involves\nsignificantly less parameters than all other methods with comparable results.\n
Fetal somatic gene therapy (1996)

Fetal somatic gene therapy is emerging as a new experimental approach, in particular to prevent irreversible perinatal disease manifestation for many inherited conditions. Early therapeutic gene application may also allow targeting of still expanding stem cell populations of organ or cell systems inaccessible later in life and help to avoid immune sensitization against the therapeutic vector system or transgene protein product. The progress in development of ultrasound scanning and embryofetoscopy over the last decade has made minimally invasive administration of therapeutic gene transfer vectors to the fetus in utero possible in principle. We review here the different considerations in choosing candidate diseases, the possible routes of administration and times in fetal development for application of a therapeutic gene and discuss the benefits and problems of present vector systems in this context. Given the many unknown aspects of fetal gene transfer, it is essential to extensively investigate this new approach to gene therapy in animal models for specific diseases, to improve on the technology of delivery and to assess efficacy of expression as well as the possible side effects before application to humans can be considered.