gebhart/patrepeval huggingface dataset:
GSI'17-Closing session (2017)

Geometric Science of Information SEE/SMF GSI’17 Conference Mines ParisTech GSI’17 General Chairmen: Frederic BARBARESCO*, Frank NIELSEN** & Silvere BONNABEL*** (*) President of SEE ISIC Club (Ingenierie des Systemes d’Information de Communications) (**) LIX Department, Ecole Polytechnique, (***) CAOR Lab, Mines ParisTech, Societe de l'electricite, de l'electronique et des technologies de l'information et de la communication GSI in center of Gerard Berry Tetrahedron Gerard Berry « Machines et Informations » 350 ans de l’Academie des Sciences https://www.youtube.com/watch?v=ajhU3GjPz1g Gerard Berry (Corps des Mines) Geometric Science of Information Souvenirs Societe de l'electricite, de l'electronique et des technologies de l'information et de la communication GSI’17 souvenirs LANGEVIN EQUATION EVERYWHERE Jean-Michel Bismut GSI’17 souvenirs CAN WE USE JOINTLY INFORMATION GEOMETRY « NATURAL GRADIENT » WITH LANGEVIN EQUATION ? YES, WITH « NATURAL LANGEVIN DYNAMICS » AND PRACTICAL FISHER MATRIX ESTIMATION Yann Ollivier GSI’17 souvenirs MARKO GIROLAMI LANGEVIN EQUATION & HAMILTONIAN MONTE CARLO METHODS Paul Langevin: Science and Actions 1917-2017 100
Morphologic Manifestations of Combined Light-chain Deposition Disease and Light-chain Cast Nephropathy (2007)

There are few data on morphology of light-chain deposition disease (LCDD) of kidney with coexistent light-chain cast nephropathy (LCCN). Here, the authors report the morphology in 23 cases of LCDD and LCCN. They retrospectively evaluated 23 renal biopsies with light (LM), immunofluorescence (IF), and electron microscopy (EM). Twenty-one patients had myeloma, 1 had a monoclonal gammopathy, and in 1 no illness was found. Nodular glomerulosclerosis, the LM lesion suggestive of LCDD, was noted in only 3 of 23 cases. Glomeruli were unremarkable in 16 (69%) cases. The diagnostic casts of LCCN were seen in all biopsies. Linear light chain (LC) immunoreactivity was observed in 23 (100%) cases (18 kappa, 5 lambda); GBM + TBM in 13, TBM only in 7, GBM only in 1, TBM and interstitium in 1, GBM, TBM and mesangium in 1. Casts were positive with same LC in all cases (100%). Fifteen cases (65%) showed granular electron-dense deposits; GBM only in 5, TBM only in 5, GBM and TBM in 4, mesangium in 1. In 8 patients without EM deposits, the diagnosis of LCDD was rendered by IF. Fifteen (65%) had deposits detectable by IF and EM, 8 (37%) had deposits with IF only. LCCN dominated the LM findings in all patients. There were minimal or no glomerular changes by LM. This study shows the lack of characteristic LM findings of LCDD in combined cases of LCDD and LCCN and emphasizes the difficulty for-definitive diagnosis-without IF and EM.
Serotonin Modifies Actin Cytoskeleton In Human Intestinal Epithelial Cells via Involvement of PKCα (2007)

Serotonin (5‐HT) inhibits intestinal Na+/H+ exchanger 3 (NHE3) activity by mechanisms not fully understood Since, NHE3 function requires an intact cytoskeleton, we hypothesized that 5‐HT inhibits NHE3 via the actin cytoskeleton. Electron microscopy (EM), immunofluorescence and immunoprecipitation were employed utilizing polarized Caco‐2 intestinal cell monolayers. EM showed that 5‐HT (0.1 μM, 1h) caused the apical membrane to assume a convex dome shape with cells displaying shorter microvilli and prominent cortical actin filaments. Fluorescence microscopy studies demonstrated that 5‐HT induced basal stress fiber assembly. This morphological actin reorganization correlated with 20 ± 1.5% (P&lt;0.05) increases in actin polymerization. Both 5‐HT3 and 5‐HT4 receptor agonists mimicked the effects of 5‐HT in inducing stress fibers and this induction was partially prevented by BAPTA‐AM and PKCα inhibition (Go6976). Immunoprecipitation studies showed that 5‐HT decreased association of PKCα with actin. These results suggested that 5‐HT‐induced actin cytoskeletal re‐organization via 5‐HT3/4 receptor subtypes and Ca2+ and PKCα dependent pathways might play an important role in inhibition of NHE3 activity.
New over current protection technology addressing DC Transportation (2016)

Fuses and Circuit Breakers play an important safety role in electrical transportation systems. Challenging new applications, especially in DC, have brought conventional current limiting devices to their limits. Indeed, mechanical circuit breakers may be too slow to open for networks with large DC fault currents. On the other hand, fuses may be too slow to open with very low DC fault currents. For AC applications, the natural zero crossing will help clear fault currents. In DC applications, the no natural zero crossing makes clearing faults by conventional current limiting technologies difficult. This paper presents a new solution to protect DC transportation using a fuse and pyroswitch hybrid system. This will apply to PV generation, energy storage, Electric Vehicles.
[P‐207]: Antioxidants in prevention of AD: Dissapointments and possibilities (2005)

Antioxidant therapy to prevent the progression of Alzheimer's disease (AD) has so far been disappointing, despite replicable evidence of oxidative stress and mitochondrial abnormalities in AD. To review the literature with the aim of finding explanations for this failure. literature review and preliminary clinical trial. Theoretical considerations have led to published suggestions that over 65 types of antioxidant would be helpful in AD. They include both natural proucts and synthetic molecules and both purified and crude preparations. Some are derived from ancient medical traditions: Chinese, Japanese, Ayurvedic, and European. Experimentally, eight antioxidant treatments have been reported to be beneficial in animal models of AD, including replicated effects of idebenone and of Vitamin E. Epidemiological studies of human populations have both supported the efficacy of Vitamins C and E (3 studies) and refuted beneficial effects (1 study). Double blind, placebo-controlled, prospective studies have lead to contradictory findings. Among substances reported to be useful in some studies and useless in others are idebenone, Vitamin E, and melatonin for sleep. Replication studies of reportedly positive results with a Japanese herbal extract (KUT) and with dihydroergokryptine have not appeared. Quantiative calculations suggest that simply ingesting nontoxic quantities of an antioxidant is likely to have little effect on the amounts of oxidatns and antioxidants produced physiologically. For instance, 2000 IU of Vitamin E is equivalent to <3% of the oxygen free radicals produced by a normal human per day. Preliminary results suggest that therapy targeted at a combination of free radical regulation and mitochondrial metabolism deserves further investigation.
UN NOUVEAU DISPOSITIF DE PERFUSION POUR L'ÉTUDE DE L'ABSORPTION INTESTINALE IN VITRO (1969)

Un nouveau dispositif permettant la perfusion in vitro d'anses intestinales isoles est dcrit. La circulation du liquide dans la lumire intestinale se fait en circuit ouvert ; la circulation du liquide du ct de la sreuse se fait en circuit ferm. Le mouvement des solutions est assur par une pompe pristaltique dbit constant.
Experimental Investigation of Silicon Surface Migration in Low Pressure Nonreducing Gas Environments (2009)

Silicon migration in four nonreducing gas ambients of helium, neon, argon, and nitrogen at a low pressure and in an ultrahigh vacuum is studied by monitoring the effect on microfabricated trench structures after a 5 min anneal at in each environment. The measurements of the trench corner curvature are used to extract the relative migration rates for each ambient. The migration rate has no ambient gas dependence for the noble gases at and has pressure dependence in the range.
Increased Prevalence of Femoroacetabular Impingement in Patients With Proximal Hamstring Tendon Injuries (2019)

Level IV, case series.
Volatile metabolites in plasma (1975)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTVolatile metabolites in plasmaElizabeth. Stoner, David. Cowburn, and Lyman C. CraigCite this: Anal. Chem. 1975, 47, 2, 344–346Publication Date (Print):February 1, 1975Publication History Published online1 May 2002Published inissue 1 February 1975https://pubs.acs.org/doi/10.1021/ac60352a004https://doi.org/10.1021/ac60352a004research-articleACS PublicationsRequest reuse permissionsArticle Views27Altmetric-Citations11LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
High-frequency and below bandgap anisotropic dielectric constants in <i>α</i>-(Al<i>x</i>Ga1−<i>x</i>)2O3 (≤x≤1) (2021)

A Mueller matrix spectroscopic ellipsometry approach was used to investigate the anisotropic dielectric constants of corundum α-(AlxGa1−x)2O3 thin films in their below bandgap spectral regions. The sample set was epitaxially grown using plasma-assisted molecular beam epitaxy on m-plane sapphire. The spectroscopic ellipsometry measurements were performed at multiple azimuthal angles to resolve the uniaxial dielectric properties. A Cauchy dispersion model was applied, and high-frequency dielectric constants are determined for polarization perpendicular (ε∞,⊥) and parallel (ε∞,∥) to the thin film c-axis. The optical birefringence is negative throughout the composition range, and the overall index of refraction substantially decreases upon incorporation of Al. We find small bowing parameters of the high-frequency dielectric constants with b⊥=0.386 and b∥=0.307.
Low-<i>k</i>films modification under EUV and VUV radiation (2013)

Modification of ultra-low-k films by extreme ultraviolet (EUV) and vacuum ultraviolet (VUV) emission with 13.5, 58.4, 106, 147 and 193 nm wavelengths and fluences up to 6 × 1018 photons cm−2 is studied experimentally and theoretically to reveal the damage mechanism and the most ‘damaging’ spectral region. Organosilicate glass (OSG) and organic low-k films with k-values of 1.8–2.5 and porosity of 24–51% are used in these experiments. The Si–CH3 bonds depletion is used as a criterion of VUV damage of OSG low-k films. It is shown that the low-k damage is described by two fundamental parameters: photoabsorption (PA) cross-section σPA and effective quantum yield φ of Si–CH3 photodissociation. The obtained σPA and φ values demonstrate that the effect of wavelength is defined by light absorption spectra, which in OSG materials is similar to fused silica. This is the reason why VUV light in the range of ∼58–106 nm having the highest PA cross-sections causes strong Si–CH3 depletion only in the top part of the films (∼50–100 nm). The deepest damage is observed after exposure to 147 nm VUV light since this emission is located at the edge of Si–O absorption, has the smallest PA cross-section and provides extensive Si–CH3 depletion over the whole film thickness. The effective quantum yield slowly increases with the increasing porosity but starts to grow quickly when the porosity exceeds the critical threshold located close to a porosity of ∼50%. The high degree of pore interconnectivity of these films allows easy movement of the detached methyl radicals. The obtained results have a fundamental character and can be used for prediction of ULK material damage under VUV light with different wavelengths.
THE EFFECT OF KE PEPTIDE ON THE TELOMERE LENGTH OF PHA-STIMULATED HUMAN LYMPHOCYTES (2019)

The goal of the research is to study the effect of KE peptide on telomere length of PHA-stimulated blood lymphocytes of young and middle-aged men. 11 blood lymphocyte samples were enrolled in the analysis. Relative telomere length was measured using fluorescence in situ hybridization with DNA-probes specific to telomere sequences of human chromosomes. 5 cases of significant telomere length alteration were registered. These changes were more frequent registered in middle-aged people: 4 invents cases versus 1. KE peptide increased telomere length in blood lymphocytes of middle-aged people if it was basically low and, vice versa, decreased the basically high telomere length.
Optical Fiber Amplifier Employing a Bundle of Reduced Cladding Erbium-Doped Fibers (2012)

We propose a novel optical amplifier that employs a bundle of reduced cladding erbium-doped fibers (EDFs) for multicore fiber transmission and successfully demonstrate the amplification of seven independent signals by employing a bundle of 60-μm cladding EDFs and a planar lightwave circuit integration technique. Average gains of 23 dB with low noise figures of less than 5.1 dB in the C-band were achieved for seven individual EDFs. We also confirmed that low crosstalk characteristics can be achieved for a multicore optical fiber amplifier by using bundled EDF.
Optical correlation measurement of switching transients in high-speed semiconductor lasers (1986)

Measurement of the large-signal transient response of a high-speed InGaAsP laser to an ultrashort rise time current pulse is reported. For complete time resolution, a measurement system which uses optical correlation techniques is implemented. Comparison is made between the optical correlation measurement and conventional electronic measurement using the fastest available detector and oscilloscope.
Microemulsion Efficiency Boosting and the Complementary Effect. 1. Structural Properties (2004)

Amphiphilic diblock copolymers added to microemulsions proved to enhance the efficiency of surfactants dramatically. The complementary effect of homopolymers is considered in the current work. A possible application of the homopolymer addition could be the viscosity tuning of the microemulsion without changing the considered bicontinuous phase. Furthermore, (homo)polymers are added for many other reasons in technical applications. A theory by Eisenriegler predicts a decreased efficiency when homopolymers are added. In further experiments, the simultaneous addition of homopolymers and diblock copolymers probes whether the two opposite effects superpose and allow for a compensation. Then, efficiency and viscosity are adjustable independently. Experimentally, phase diagrams are investigated and the microscopic structure is measured by small-angle neutron scattering. Within the presented models, both experimental methods are compared and discussed on the basis of the surfactant membrane bending moduli. The homopolymer effect is about 7 times larger than that theoretically predicted, and the superposition of the two polymer effects allows for a compensation with an optionally tunable viscosity.
Is Selective Internal Radioembolization Safe and Effective for Patients with Inoperable Hepatocellular Carcinoma and Venous Thrombosis? (2009)

SIR is safe in patients with HCC. Although SIR can be delivered with minimal morbidity, there might be no benefit for patients with VT. Continued emphasis on multimodality therapy in this population is needed to improve survival.
Stratification, segregation, and mixing of granular materials in quasi-two-dimensional bounded heaps (2012)

Segregation and mixing of granular mixtures during heap formation has important consequences in industry and agriculture. This research investigates three different final particle configurations of bidisperse granular mixtures--stratified, segregated and mixed--during filling of quasi-two-dimensional silos. We consider a large number and wide range of control parameters, including particle size ratio, flow rate, system size, and heap rise velocity. The boundary between stratified and unstratified states is primarily controlled by the two-dimensional flow rate, with the critical flow rate for the transition depending weakly on particle size ratio and flowing layer length. In contrast, the transition from segregated to mixed states is controlled by the rise velocity of the heap, a control parameter not previously considered. The critical rise velocity for the transition depends strongly on the particle size ratio.
The Membrane Proteinase 3 Expression on Neutrophils Was Downregulated After Treatment With Infliximab in Patients With Rheumatoid Arthritis (2008)

Proteinase 3 (PR3) expression on neutrophils was examined in rheumatoid arthritis (RA) patients before and after antitumor necrosis factor (TNF)-alpha therapy. Membrane PR3 expression from patients with either an infection or RA significantly increased. Membrane PR3 expression on neutrophils from RA patients treated with infliximab (anti-TNF-alpha antibody) therapy was less than in those without such treatment in a resting state, but the expression later increased after stimulation in vitro. Membrane PR3 expression increased because of the stimulation of TNFalpha, whereas it was significantly suppressed by plasma or alpha(1)-proteinase inhibitor. The condition of patients with RA improved after treatment with infliximab. Membrane PR3 expression on neutrophils in RA patients was downregulated by infliximab. As a result, PR3 might play an important role in the neutrophil-mediated inflammatory reaction in patients with either RA or an infection.
Cerebrospinal Fluid Clearance in Alzheimer Disease Measured with Dynamic PET (2017)

Evidence supporting the hypothesis that reduced cerebrospinal fluid (CSF) clearance is involved in the pathophysiology of Alzheimer disease (AD) comes primarily from rodent models. However, unlike rodents, in which predominant extracranial CSF egress is via olfactory nerves traversing the cribriform plate, human CSF clearance pathways are not well characterized. Dynamic PET with <sup>18</sup>F-THK5117, a tracer for tau pathology, was used to estimate the ventricular CSF time-activity as a biomarker for CSF clearance. We tested 3 hypotheses: extracranial CSF is detected at the superior turbinates; CSF clearance is reduced in AD; and CSF clearance is inversely associated with amyloid deposition. <b>Methods:</b> Fifteen subjects, 8 with AD and 7 normal control volunteers, were examined with <sup>18</sup>F-THK5117. Ten subjects additionally underwent <sup>11</sup>C-Pittsburgh compound B (<sup>11</sup>C-PiB) PET scanning, and 8 were <sup>11</sup>C-PiB-positive. Ventricular time-activity curves of <sup>18</sup>F-THK5117 were used to identify highly correlated time-activity curves from extracranial voxels. <b>Results:</b> For all subjects, the greatest density of CSF-positive extracranial voxels was in the nasal turbinates. Tracer concentration analyses validated the superior nasal turbinate CSF signal intensity. AD patients showed ventricular tracer clearance reduced by 23% and 66% fewer superior turbinate CSF egress sites. Ventricular CSF clearance was inversely associated with amyloid deposition. <b>Conclusion:</b> The human nasal turbinate is part of the CSF clearance system. Lateral ventricle and superior nasal turbinate CSF clearance abnormalities are found in AD. Ventricular CSF clearance reductions are associated with increased brain amyloid depositions. These data suggest that PET-measured CSF clearance is a biomarker of potential interest in AD and other neurodegenerative diseases.
Carcinogen 4-Nitroquinoline Oxide (4-NQO) Induces Oncostatin-M (OSM) in Esophageal Cells (2023)

Induction of OSM in chemically-induced esophageal cancer in mice correlates with the appearance of senescent cells.
Effects of Multiple Influence Quantities on Rogowski-Coil-Type Current Transformers (2019)

This article presents a study on low-power passive current transformers. In particular, the performance of three Rogowski coils has been assessed when multiple influence quantities were acting on them: conductor position, frequency, and ambient temperature. First of all, their single effects have been assessed, then all their possible combinations have been tested. From the results, it can be concluded that the ratio error is mostly affected by the combination of uncentered positions and temperatures applied to Rogowski coils. Contrastingly, the phase error is substantially not influenced by any quantity. Therefore, the proposed set of tests could become a benchmark in Rogowski coil testing.
Assessing changes in thermally upgraded papers with different nitrogen contents under accelerated aging (2017)

Thermally upgraded Kraft (TUK) "Insuldur®" papers prepared from the same batch process but with a different percentage of stabilizing additives (1.2, 2.6 and 4.4% of nitrogen) were studied under accelerated aging at 170 °C. The increment of stabilizing additives in paper with the consequent increment of nitrogen content slows down the rate of molecular chain scission of the cellulose and reduces the paper tensile strength loss rate. However, a progressive reduction in the enhancement of the paper life span by the increment of nitrogenous additives in paper was observed. The cellulose degradation methanol and ethanol markers were found to be reliable and accurate for tracking the aging of TUK papers even with the variation of nitrogen content in paper. A promising correlation between methanol concentration and the paper tensile index with different nitrogen content was determined. This correlation could be used as a basis for developing tools to assess power transformers residual life. FTIR-ATR analyses of dicyandiamide in aged papers showed a rapid reaction and decomposition of dicyandiamide in other compounds that slows down cellulose aging. The nitrogen content of aged paper, measured with the Dumas method, showed a slight variation during the study. This implies that the nitrogen compounds continue to be attached, presumably by polar forces to the paper. Thermogravimetric analysis (TGA) of new and aged Insuldur® paper samples showed that nitrogen additives improve the thermal stability of paper at high temperatures.
Approaches to the analysis of cell signaling networks and their application in drug discovery. (2005)

The ability to predict the safety and efficacy of novel drugs prior to clinical testing is a key goal in pharmaceutical drug discovery. Gaining a mechanistic understanding of the complex cell signaling networks (CSNs) underlying disease processes promises to help reduce the number of clinical failures by identifying points of intervention as well as redundancies and feedback mechanisms that contribute to toxicities, lack of efficacy and unexpected biological activities. Experimental and computational approaches to analyzing and modeling CSNs are currently being validated using simple organisms and cell lines. In vitro cell systems of sufficient complexity to resemble human disease physiology, but which are also amenable to chemical and genetic perturbations on a large scale, are now required for deciphering the signaling networks operating in human disease. In this review, experimental and computational methods for modeling complex CSNs and the applications of these approaches to pharmaceutical drug discovery are discussed.
Loss of CD44 variant 6 expression differentiates small cell carcinoma of urinary bladder from urothelial (transitional cell) carcinoma (1998)

CD44v6 immunostaining discriminates cases of poorly differentiated urothelial carcinoma from small cell carcinoma. It also highlights the presence of mixed small cell urothelial differentiation when present.