gebhart/patrepeval huggingface dataset:
Dynamic deformation textures (2007)

Article Share on Dynamic deformation textures: GPU-accelerated simulation of deformable models in contact Authors: Nico Galoppo UNC Chapel Hill UNC Chapel HillView Profile , Miguel A. Otaduy ETH Zurich ETH ZurichView Profile , Paul Mecklenburg UNC Chapel Hill UNC Chapel HillView Profile , Markus Gross ETH Zurich ETH ZurichView Profile , Ming C. Lin UNC Chapel Hill UNC Chapel HillView Profile Authors Info & Claims SIGGRAPH '07: ACM SIGGRAPH 2007 coursesAugust 2007 Pages 59–79https://doi.org/10.1145/1281500.1281669Online:05 August 2007Publication History 5citation20DownloadsMetricsTotal Citations5Total Downloads20Last 12 Months2Last 6 weeks0 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteGet Access
Investigation of CVD graphene topography and surface electrical properties (2016)

Combining scanning probe microscopy techniques to characterize samples of graphene, a selfsupporting, single atomic layer hexagonal lattice of carbon atoms, provides far more information than a single technique can. Here we focus on graphene grown by chemical vapour deposition (CVD), grown by passing carbon containing gas over heated copper, which catalyses single atomic layer growth of graphene on its surface. To be useful for applications the graphene must be transferred onto other substrates. Following transfer it is important to characterize the CVD graphene. We combine atomic force microscopy (AFM) and scanning Kelvin probe microscopy (SKPM) to reveal several properties of the transferred film. AFM alone provides topographic information, showing 'wrinkles' where the transfer provided incomplete substrate attachment. SKPM measures the surface potential indicating regions with different electronic properties for example graphene layer number. By combining AFM and SKPM local defects and impurities can also be observed. Finally, Raman spectroscopy can confirm the structural properties of the graphene films, such as the number of layers and level of disorder, by observing the peaks present. We report example data on a number of CVD samples from different sources.
Hormone-Induced Protection of Mammary Tumorigenesisin Genetically Engineered Mouse Models (2011)

Introduction In the post-genome era, a major challenge is deciphering the function of thousands of newly identied genes. One of the main approaches for studying gene function involves inactivation of genes in cells or animals using random (chemical or insertional) mutagenesis or gene targeting. A common problem with these methods stems from the fact that the gene of interest is usually mutated throughout the animal’s life. As a result, 1) in many cases the mutation leads to embryonic or neonatal lethality, precluding the assessment of the gene’s function in later life; 2) in viable mutants interpretation of observed phenotypes is often complicated by the inability to distinguish the direct eects of the gene loss at the time of observation from the results of developmental abnormalities caused by the gene loss earlier in life; 3) in still other cases, life-long absence of a gene product causes compensatory adjustments of activities of other genes precluding the elucidation of the function of the gene of interest. Conditional knockout and gene expression technologies, such as the Cre/lox-mediated tissue-specic knockout [1] and the tetracycline (Tet) regulated transcriptional activation system [2], can regulate gene expression in a more spatially and temporally controlled fashion. However, these technologies are often laborious to establish and the results are frequently variable.
Customized hydrogel substrates for serum-free expansion of functional hMSCs (2020)

We describe a screening approach to identify customized substrates for serum-free human mesenchymal stromal cell (hMSC) culture. In particular, we combine a biomaterials screening approach with design of experiments (DOE) and multivariate analysis (MVA) to understand the effects of substrate stiffness, substrate adhesivity, and media composition on hMSC behavior in vitro. This approach enabled identification of poly(ethylene glycol)-based and integrin binding hydrogel substrate compositions that supported functional hMSC expansion in multiple serum-containing and serum-free media, as well as the expansion of MSCs from multiple, distinct sources. The identified substrates were compatible with standard thaw, seed, and harvest protocols. Finally, we used MVA on the screening data to reveal the importance of serum and substrate stiffness on hMSC expansion, highlighting the need for customized cell culture substrates in optimal hMSC biomanufacturing processes.
Genetic analysis of spo0A and spo0C mutants of Bacillus subtilis with a phi 105 prophage merodiploid system (1985)

An 8.0-kilobase chromosomal fragment of Bacillus subtilis which contained an intact spo0A gene was recloned onto temperate phage phi 105 from the rho 11dspo0A+-1 transducing phage. A specialized transducing phage, phi 105-dspo0A+-1, was constructed and used to transduce the spo0A12 mutant strain 1S9. A Spo+ transductant which was a single lysogen of the phi 105dspo0A+-1 transducing phage was isolated. From competent cells of this Spo+ transductant was isolated a Spo- (Spo0A) strain which was immune to phi 105. It was used to prepare a lysate of the phi 105dspo0A12 phage. Transduction of the spo0C9V recE4 strain with the phi 105dspo0A12 and phi 105dspo0A+-1 phages was carried out. The phi 105dspo0A+-1 phage gave rise to a large number of heat-resistant cells, but the phi 105dspo0A12 phage formed no heat-resistant cells. These results indicate that the spo0A12 and spo0C9V mutant genes do not complement each other in the ability to sporulate and that the spo0C9V mutation is located within the spo0A gene. Although the spo0C9V strain was completely asporogenous, the spo0C9V/spo0C9V diploid strain produced heat-resistant cells at a frequency of ca. 10(-3) in the sporulation medium. This result indicates that two copies of the spo0C9V mutant gene partially restore the ability of these cells to sporulate.
Correlation between molecular structure, free volume, and physical properties of a wide range of main chain thermotropic liquid crystalline polymers (2001)

Abstract Physical phenomena such as glass transition temperatures, melting points, and relaxational behavior have been determined for a wide range of thermotropic liquid crystalline polymers (TLCPs) and polycarbonate (PC). Damping intensities of rigid TLCPs during glass transition are greater than those of semirigid and semiflexible TLCPs. Positron annihilation lifetime spectroscopy was also employed to evaluate free volume parameters of polymers. In general, the positron annihilation lifetime spectroscopy (PALS) free volume parameters show that all TLCPs have much smaller, fewer free volume sites compared with PC. Correlations were found between PALS free volume parameters and glass transition temperature, dynamic mechanical damping strength, and bulk density where greater free volume parameters corresponded to higher glass transition temperatures, greater damping strength, and lower density. © 2001 John Wiley &amp; Sons, Inc. J Appl Polym Sci 82: 2252–2267, 2001
Structural analysis of an infrared focal plane dewar assembly for meteorological satellite (2018)

This paper designs a vacuum packaged Dewar for meteorological satellites. It integrates an 80 × 1 long wavelength photodetector with a wavelength of 13.2 &mu;m to 13.8 &mu;m and a dual band focal plane detector with a wavelength of 10.3um-11.3um / 11.5um-12.5um. The detector uses a mechanical cooler to reach an operating temperature of 60K. The theoretical calculation and simulation analysis are carried out from two aspects: cold load and mechanical vibration of Dewar. The analysis shows that when the ambient temperature is room temperature and the detector operating temperature is 60K, the total heat loads of the cold plate is 1.25W. Where the wires loss accounts for about 36% of the total heat load and the detector Joule heat accounts for about 21%. The mechanical vibration analysis of Dewar shows that the cold plate pillar is the main factor affecting the mechanical properties of the structure. Increasing the pillar support increases the base frequency of the Dewar from 379 Hz to 539 Hz, thereby increasing the mechanical base frequency of the Dewar components.
Quantification of Xrcc and DNA-PK Proteins in Cancer Cell Lines and Human Tumors by LC–MS/MS (2014)

The assay range is 0.140-450 fmol (coefficient of variation: 25%) for XRCC4 in bovine serum albumen. The quantitative protein expression levels for XRCC and DNA-PK in HeLa, Ramos and HEK-293 cells and tumor tissues (lung and lymphoma) are reported.
Excited-state transient of vanadyl uroporphyrin I detected by resonance Raman spectroscopy (1990)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTExcited-state transient of vanadyl uroporphyrin I detected by resonance Raman spectroscopyRhett G. Alden, Laurie D. Sparks, Mark R. Ondrias, Beverly A. Crawford, and John A. ShelnuttCite this: J. Phys. Chem. 1990, 94, 4, 1440–1443Publication Date (Print):February 1, 1990Publication History Published online1 May 2002Published inissue 1 February 1990https://pubs.acs.org/doi/10.1021/j100367a044https://doi.org/10.1021/j100367a044research-articleACS PublicationsRequest reuse permissionsArticle Views79Altmetric-Citations2LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Effects of cell cycle status on early events in retroviral replication (2005)

The study of retroviruses over the last century has revealed a wide variety of disease-producing mechanisms, as well as apparently harmless interactions with animal hosts. Despite their potential pathogenic properties, the intrinsic features of retroviruses have been harnessed to create gene transfer vectors that may be useful for the treatment of disease. Retroviruses, as all viruses, have evolved to infect specific cells within the host, and such specificities are relevant to both pathogenesis and retrovirus-based vector design. The majority of cells of an animal host are not progressing rapidly through the cell cycle, and such a cellular environment appears to be suboptimal for replication of all retroviruses. Retrovirus-based vectors can therefore be restricted in many important target cells, such as post-mitotic differentiated cells or stem cells that may divide only infrequently. Despite intense interest, our understanding of how cell cycle status influences retroviral infection is still quite limited. In this review, we focus on the importance of the cell cycle as it relates to the early steps in retroviral replication. Retroviruses have been categorized based on their abilities to complete these early steps in non-cycling cells. However, all retroviruses are subject to a variety of cell cycle restrictions. Here, we discuss such restrictions, and how they may block retroviral replication, be tolerated, or overcome.
Type 2 diabetes mellitus, brain atrophy, and cognitive decline (2019)

In an older cohort with low cerebrovascular disease burden, T2DM contributes to cognitive decline via neurodegeneration. Prior brain and cognitive reserve may protect against this effect.
Figure S5 from Optimized EGFR Blockade Strategies in &lt;i&gt;EGFR&lt;/i&gt; Addicted Gastroesophageal Adenocarcinomas (2023)

&lt;p&gt;Supplementary Figure 5&lt;/p&gt;
Effects of increasing oregano oil on nursery pig performance (2005)

A total of 210 nursery pigs (PIC L327 Ã— L42), with an initial weight of 11.9 lb and 21 d of age, were used in a 28-d growth study. The objective was to evaluate the effects of increasing oregano oil in diets for nursery pigs. Oregano oil is an extract derived from the Greek herb, Origanum vulgare, and has been speculated to have antimicrobial-like activity. Previous research at Kansas State University showed no improvement in growth performance in nursery pigs fed oregano oil (0.10% in the Phase 1 diet, and 0.05% in Phase 2). The present study evaluated growth performance of pigs fed diets containing either 0.05%, 0.10%, or 0.20% oregano oil for the entire 28-d study. There was no improvement in ADG, ADFI, F/G, or d-28 weights of pigs fed diets containing oregano oil, compared with performance of pigs fed the control diets. Also, there was no effect (P>0.15) of increasing the amount of oregano oil in the diet. But pigs fed neomycin-oxytetracycline had improved ADG, ADFI, and F/G (P<0.03), compared with those of pigs fed the control and oregano oil treatments, from d 0 to 14. Overall, (d 0 to 28), pigs fed neomycinoxytetracycline had better ADG and ADFI (P<0.006) than the pigs fed the control diet had, and better ADG, ADFI, F/G, and final body weight (P<0.04) than pigs fed the oregano oil treatment had.; Swine Day, 2005, Kansas State University, Manhattan, KS, 2005
Programmed Death - Ligand 1 Expression Distinguishes Invasive Encapsulated Follicular Variant of Papillary Thyroid Carcinoma from Noninvasive Follicular Thyroid Neoplasm with Papillary-like Nuclear Features (2017)

PD-L1 expression may serve as a useful biomarker in predicting invasiveness of EFVPTC and distinguishing NIFTP from invasive EFVPTC. To our knowledge this is the first report suggesting the application of a protein biomarker to confirm NIFTP as benign indolent neoplasms.
Correction. N-Bridgehead Polycyclic Compounds by Sequential Rearrangement-Annulation of Isoxazoline-5-spirocyclopropanes. 6. A General Synthetic method for 5,6-Dihydro-7(8H)- and 2,3,5,6-Tetrahydro-7(1H)-indoliziones. (1992)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCorrection. N-Bridgehead Polycyclic Compounds by Sequential Rearrangement-Annulation of Isoxazoline-5-spirocyclopropanes. 6. A General Synthetic method for 5,6-Dihydro-7(8H)- and 2,3,5,6-Tetrahydro-7(1H)-indoliziones.Ernesto Occhiato, Antonio Guarna, Alberto Brandi, Andrea Goti, and Francesco De SarloCite this: J. Org. Chem. 1992, 57, 26, 7373Publication Date (Print):December 1, 1992Publication History Published online15 October 2003Published inissue 1 December 1992https://pubs.acs.org/doi/10.1021/jo00052a603https://doi.org/10.1021/jo00052a603research-articleACS PublicationsRequest reuse permissionsArticle Views31Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
A Simple Risk Score for the Assessment of Absolute Fracture Risk in General Practice Based on Two Longitudinal Studies (2008)

The aim of this prospective study was to develop a risk score, based on putative risk factors in current guidelines, which can be used to identify women at high risk of fractures in general practice. The study sample included 4157 women >/=60 yr of age (mean +/- SD: 74.1 +/- 9.1 yr), with a median follow-up of 8.9 yr of the Rotterdam Study (ERGO), and 762 women >/=65 yr of age (mean +/- SD: 76.0 +/- 6.7.yr), with a median follow-up of 6.0 yr of the Longitudinal Aging Study Amsterdam (LASA). Potential risk factors were those proposed in risk scores of three recent guidelines on osteoporosis: age, family history of fractures, prior fracture, low body weight/body mass index (BMI), serious immobility, rheumatoid arthritis, current smoking, alcohol consumption >2 units daily, prevalent vertebral fracture, and systemic corticosteroid use. Five-year absolute risk of hip fracture was 3.9% in the Rotterdam Study and 3.1% in LASA, and 10-yr absolute risk of hip fracture was 8.4% in the Rotterdam Study. Using Cox regression analysis, age (70-79 and 80+ versus <60-69) and four other risk factors were included in the risk profiles of hip fractures and fragility fractures: any prior fracture after age 50, body weight <64 kg, use of a walking aid as a proxy measure of serious immobility, and current smoking. Estimated 10-yr absolute risk of hip fracture ranged from 1.4% in women, age 60-69 years, without any of these predictors to 29% in women, >/=80 yr of age, having two or more positive risk factors. A simple risk score can satisfactorily identify older women at high risk of osteoporotic fractures in general practice. Future studies are needed to validate this score.
A comparison of labeling schemes for ancestor queries (2002)

Motivated by a recent application in XML search engines we study the problem of labeling the nodes of a tree (XML file) such that given the labels of two nodes one can determine whether one node is an ancestor of the other. We describe several new prefix-based labeling schemes, where an ancestor query roughly amounts to testing whether one label is a prefix of the other. We compare our new schemes to a simple interval-based scheme currently used by search engines, as well as, to schemes with the best theoretical guarantee on the maximum label length. We performed our experimental evaluation on real XML data and on some families of random trees.
Bench-to-bedside review: Sepsis - from the redox point of view (2011)

The pathogenesis of sepsis and its progression to multiple organ dysfunction syndrome and septic shock have been the subject of investigations for nearly half a century. Controversies still exist with regard to understanding the molecular pathophysiology of sepsis in relation to the complex roles played by reactive oxygen species, nitric oxide, complements and cytokines. In the present review we categorise the key turning points in sepsis development and outline the most probable sequence of events leading to cellular dysfunction and organ failure under septic conditions. We have applied an integrative approach in order to fuse current state-of-the-art knowledge about redox processes involving hydrogen peroxide, nitric oxide, superoxide, peroxynitrite and hydroxyl radical, which lead to mitochondrial respiratory dysfunction. Finally, from this point of view, the potential of redox therapy targeting sepsis is discussed.
Time and space efficient spectral clustering via column sampling (2011)

Spectral clustering is an elegant and powerful approach for clustering. However, the underlying eigen-decomposition takes cubic time and quadratic space w.r.t. the data set size. These can be reduced by the Nyström method which samples only a subset of columns from the matrix. However, the manipulation and storage of these sampled columns can still be expensive when the data set is large. In this paper, we propose a time- and space-efficient spectral clustering algorithm which can scale to very large data sets. A general procedure to orthogonalize the approximated eigenvectors is also proposed. Extensive spectral clustering experiments on a number of data sets, ranging in size from a few thousands to several millions, demonstrate the accuracy and scalability of the proposed approach. We further apply it to the task of image segmentation. For images with more than 10 millions pixels, this algorithm can obtain the eigenvectors in 1 minute on a single machine.
Intelligent Cellular Offloading With VLC-Enabled Unmanned Aerial Vehicles (2023)

This article discusses a cellular network assisted by an energy- and spectral-efficient unmanned aerial vehicle (UAV), in which the UAV is deployed to serve mobile users in the cellular network and enable mobile data offloading from a ground base station (GBS) by taking a circular flight route. We explore a visible light communication (VLC)-enabled UAV, in which a light-emitting diode (LED) is mounted on a rotary-wing UAV to offer communications to the users. Our aim is to simultaneously optimize both energy efficiency (EE) and spectral efficiency (SE) of the VLC-enabled UAV by jointly optimizing the common throughput of all users as well as the UAV’s trajectory and flying speed. We employ a unified metric, called resource efficiency (RE), and explore the RE optimization to obtain an adaptive EE–SE tradeoff. The problem posed is seen in a complex and nonconvex shape, making it hard to solve. Motivated by the enormous achievement of deep reinforcement learning (DRL) in solving complex control problems, we propose a DRL-based approach to handle this nonconvex and complicated optimization. The findings of the simulation reveal that the developed framework achieves a substantial performance in terms of the solution convergence as well as the promising quality of the solutions.
Room-temperature optically pumped laser emission from <i>a</i>-plane GaN with high optical gain characteristics (2004)

Photoluminescence (PL) and optical gain (OG) spectra of a-plane GaN layers have been analyzed over a wide range of excitation intensities. The samples were fully coalesced layers grown by metalorganic chemical vapor deposition over r-plane sapphire substrates using epitaxial layer overgrowth (ELOG) and selective area lateral epitaxy (SALE) procedures. ELOG and SALE a-plane samples showed a strong stimulated emission line in backscattering-geometry PL spectra along with extremely high OG coefficient values (in SALE samples more than 2000 cm−1). Structures prepared with natural cleaved facet cavities based on these films were used to demonstrate optically pumped room-temperature lasing.