gebhart/patrepeval huggingface dataset:
Effect of Reduction in the Use of Computed Tomography on Clinical Outcomes of Appendicitis (2015)

Among children with suspected appendicitis, the use of US imaging has increased substantially as the use of CT has declined. Despite the increased reliance on the diagnostically inferior US, important condition-specific quality measures, including the frequency of appendiceal perforation and ED revisits, remained stable, and the proportion of negative appendectomy declined slightly.
Bioelectrical impedance analysis to estimate body composition, and change in adiposity, in overweight and obese adolescents: comparison with dual-energy x-ray absorptiometry (2014)

The Tanita BIA8 could be a valuable clinical tool to measure body composition at the group level, but is inaccurate for the individual obese adolescent.
DETERMINATION AND SIGNIFICANCE OF RESILENT BIMODULAR PROPERTIES OF STABILIZED SOILS (1978)

The differences between the values of resilient moduli of stabilized soils measured by using repeated compression, tension flexure, and split-tension tests and the actual resilient moduli in tension and compression are explained analytically. Results indicate that values of resilient moduli measured by using repeated tension and compression tests agree well with actual values for specimens that have length-to-width ratios of 2 and caps that are at least ten times as stiff as the stabilized material in compression. Repeated flexure tests give values of resilient moduli that are lower or higher than actual values, depending on the dimensions of the specimen, the fixity at points of load application, and the method of calculation used. However, a good estimate of resilient moduli in tension and compression can be obtained for beam specimens that have length-to-width ratios equal to 4 and no lateral supports at points of load application by using simple beam-theory assumptions for a bimodular material (i.e. different moduli in tension and compression). A procedure for the determination of resilient bimodular properties (i.e., resilient tensile and compressive moduli) by using the repeated split-tension test is developed and gives values for resilient moduli in tension and compression that do not deviate from the actual values by more than 16 and 11 percent respectively. The significance of the resilient bimodular properties on the response of stabilized layers under traffic loads is assessed analytically. The results show that tensile stresses and strains on the underside of the stabilized layer are highly influenced by the resilient compressive and tensile moduli of the material. /Author/
<i>Xanthomonas campestris</i> pv. campestris <i>gum</i> Mutants: Effects on Xanthan Biosynthesis and Plant Virulence (1998)

Xanthan is an industrially important exopolysaccharide produced by the phytopathogenic, gram-negative bacterium Xanthomonas campestris pv. campestris. It is composed of polymerized pentasaccharide repeating units which are assembled by the sequential addition of glucose-1-phosphate, glucose, mannose, glucuronic acid, and mannose on a polyprenol phosphate carrier (L. Ielpi, R. O. Couso, and M. A. Dankert, J. Bacteriol. 175:2490-2500, 1993). A cluster of 12 genes in a region designated xpsI or gum has been suggested to encode proteins involved in the synthesis and polymerization of the lipid intermediate. However, no experimental evidence supporting this suggestion has been published. In this work, from the biochemical analysis of a defined set of X. campestris gum mutants, we report experimental data for assigning functions to the products of the gum genes. We also show that the first step in the assembly of the lipid-linked intermediate is severely affected by the combination of certain gum and non-gum mutations. In addition, we provide evidence that the C-terminal domain of the gumD gene product is sufficient for its glucosyl-1-phosphate transferase activity. Finally, we found that alterations in the later stages of xanthan biosynthesis reduce the aggressiveness of X. campestris against the plant.
RNA sequencing of cancer reveals novel splicing alterations (2013)

Breast cancer transcriptome acquires a myriad of regulation changes, and splicing is critical for the cell to "tailor-make" specific functional transcripts. We systematically revealed splicing signatures of the three most common types of breast tumors using RNA sequencing: TNBC, non-TNBC and HER2-positive breast cancer. We discovered subtype specific differentially spliced genes and splice isoforms not previously recognized in human transcriptome. Further, we showed that exon skip and intron retention are predominant splice events in breast cancer. In addition, we found that differential expression of primary transcripts and promoter switching are significantly deregulated in breast cancer compared to normal breast. We validated the presence of novel hybrid isoforms of critical molecules like CDK4, LARP1, ADD3, and PHLPP2. Our study provides the first comprehensive portrait of transcriptional and splicing signatures specific to breast cancer sub-types, as well as previously unknown transcripts that prompt the need for complete annotation of tissue and disease specific transcriptome.
The London penetration depth in BaFe<sub>2</sub>As<sub>2</sub>superconductors at high electron doping level (2010)

We compare the temperature dependences of the in-plane London penetration depth (Δλab(T)) for several Ba(Fe1 − xTMx)2As2 (TM = Co, Ni, Pd, Co + Cu) superconductors at high concentration of electrons, ne, added per Fe site. We show that regardless of the transition metal TM, for ne ≥ 0.12, the penetration depth has a power-law temperature dependence , but with the exponent n≈1.65, thus significantly lower than the value n ≥ 2 previously reported for lower electron concentrations. On doping with electrons from the 3d shells, the magnitude of the variation with temperature of ΔλL(T) is larger for Ni substitution than for Co substitution, and larger for Co + Cu co-doping than for Ni co-doping. However, comparing the effect of 3d and 4d electrons, for the isovalent elements Ni and Pd respectively, we found that the rates of change in penetration depth with temperature are nearly identical for the two compounds.
Clinical Neurosciences and Alzheimer's Disease (1996)

Research Article| March 01 1996 Clinical Neurosciences and Alzheimer's Disease Ramon Cacabelos Ramon Cacabelos 1Institute for CNS Disorders, Basic and Clinical Neurosciences Research Centre, La Coruña and Neurogerontology Unit, Department of Physiology, School of Medicine, Complutense University, Madrid, Spain Search for other works by this author on: This Site PubMed Google Scholar Clin Sci (Lond) (1996) 90 (3): 153–156. https://doi.org/10.1042/cs0900153 Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn Email Cite Icon Cite Get Permissions Citation Ramon Cacabelos; Clinical Neurosciences and Alzheimer's Disease. Clin Sci (Lond) 1 March 1996; 90 (3): 153–156. doi: https://doi.org/10.1042/cs0900153 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsClinical Science Search Advanced Search This content is only available as a PDF. © 1996 The Biochemical Society and the Medical Research Society1996 Article PDF first page preview Close Modal You do not currently have access to this content.
Bora-aromatic systems. 9. Di-.pi.-methane-like photorearrangement of dimesityl(mesitylethynyl)borane: synthesis, structure, and aromaticity of trimesitylborirene (1987)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTBora-aromatic systems. 9. Di-.pi.-methane-like photorearrangement of dimesityl(mesitylethynyl)borane: synthesis, structure, and aromaticity of trimesitylborireneJohn J. Eisch, Babak Shafii, and Arnold L. RheingoldCite this: J. Am. Chem. Soc. 1987, 109, 8, 2526–2528Publication Date (Print):April 1, 1987Publication History Published online1 May 2002Published inissue 1 April 1987https://pubs.acs.org/doi/10.1021/ja00242a055https://doi.org/10.1021/ja00242a055research-articleACS PublicationsRequest reuse permissionsArticle Views424Altmetric-Citations67LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
Spectroscopic and diffraction studies of polyaniline and polyblends of polyaniline with commercial polymers processed by counter-ion induced processibility (1994)

Summary form only given. When processed through counterion-induced processibility, polyaniline (PANI), either neat or in polyblends with commercial polymers, exhibits better quality than earlier PANI materials. This progress enables a variety technical applications for PANI-based materials as conducting polymers; it also enables a better understanding of structure of polyaniline. We will present the results of spectroscopic and diffraction studies of PANI, neat and in polyblends, in both conducting and non-conducting forms with emphasis on tensile-draw polyblend samples. The results are discussed and compared with data published previously on related PANI materials.
Towards Software Component Procurement Automation with Latent Semantic Analysis (2007)

One of the first steps of component procurement is the identification of required component features in large repositories of existing components. On the highest level of abstraction, component requirements as well as component descriptions are usually written in natural language. Therefore, we can reformulate component procurement as a text analysis problem and apply latent semantic analysis for automatically identifying suitable existing components in large repositories, based on the descriptions of required component features. In this article, we motivate our choice of this technique for feature identification, describe how it can be applied to feature tracing problems, and discuss the results that we achieved with the application of this technique in a number of case studies.
The impact of the flow arrival process in Internet traffic (2004)

Internet packet data is analysed to determine the relationship between the arrival process of packets, and of TCP flows of packets. Viewed as point processes, second order properties of the two processes are studied using wavelets, and each is found to have long range dependence. A new result is given directly linking flow durations to the onset scale of the long range dependence in the flow process. Using this result, a mechanism is described whereby the flow level structure could, in principle, influence the packet level structure, and it is shown and explained why this is not the case currently. The circumstances under which the flow structure could impact on the packet process, and therefore become important for the modeling of the packet level dynamics, are given.
Predicting resolution and image quality in RESOLFT and other point scanning microscopes [Invited] (2020)

The performance of fluorescence microscopy and nanoscopy is often discussed by the effective point spread function and the optical transfer function. However, due to the complexity of the fluorophore properties such as photobleaching or other forms of photoswitching, which introduce a variance in photon emission, it is not trivial to choose optimal imaging parameters and to predict the spatial resolution. In this paper, we analytically derive a theoretical framework for estimating the achievable resolution of a microscope depending on parameters such as photoswitching, labeling densities, exposure time and sampling. We developed a numerical simulation software to analyze the impact of reversibly switchable probes in RESOLFT imaging.
Biomarker Testing in Lung Carcinoma Cytology Specimens: A Perspective From Members of the Pulmonary Pathology Society (2016)

The advent of targeted therapy in lung cancer has heralded a paradigm shift in the practice of cytopathology with the need for accurately subtyping lung carcinoma, as well as providing adequate material for molecular studies, to help guide clinical and therapeutic decisions. The variety and versatility of cytologic-specimen preparations offer significant advantages to molecular testing; however, they frequently remain underused. Therefore, evaluating the utility and adequacy of cytologic specimens is critical, not only from a lung cancer diagnosis standpoint but also for the myriad ancillary studies that are necessary to provide appropriate clinical management. A large fraction of lung cancers are diagnosed by aspiration or exfoliative cytology specimens, and thus, optimizing strategies to triage and best use the tissue for diagnosis and biomarker studies forms a critical component of lung cancer management. This review focuses on the opportunities and challenges of using cytologic specimens for molecular diagnosis of lung cancer and the role of cytopathology in the molecular era.
Low‐Cost, High‐Pressure‐Synthesized Oxygen‐Entrapping Materials to Improve Treatment of Solid Tumors (2023)

Tumor hypoxia drives resistance to many cancer therapies, including radiotherapy and chemotherapy. Methods that increase tumor oxygen pressures, such as hyperbaric oxygen therapy and microbubble infusion, are utilized to improve the responses to current standard-of-care therapies. However, key obstacles remain, in particular delivery of oxygen at the appropriate dose and with optimal pharmacokinetics. Toward overcoming these hurdles, gas-entrapping materials (GeMs) that are capable of tunable oxygen release are formulated. It is shown that injection or implantation of these materials into tumors can mitigate tumor hypoxia by delivering oxygen locally and that these GeMs enhance responsiveness to radiation and chemotherapy in multiple tumor types. This paper also demonstrates, by comparing an oxygen (O<sub>2</sub> )-GeM to a sham GeM, that the former generates an antitumorigenic and immunogenic tumor microenvironment in malignant peripheral nerve sheath tumors. Collectively the results indicate that the use of O<sub>2</sub> -GeMs is promising as an adjunctive strategy for the treatment of solid tumors.
In‐situ‐Visualisierung von Oberflächendeformationen aufgrund konvektiver Stoffströme während der Prozessierung flüssig applizierter Polymerbeschichtungen (2010)

Messwerte mit einer einzigen Adsorbat-Lösemittel-Isothermen-(ALI)
ChemInform Abstract: Some Aspects of the Chemistry of Silylidene‐Phosphanes and ‐Arsanes (1996)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
One-Step Synthesis of Sugar Nucleotides (2020)

The chemical synthesis of sugar nucleotides requires a multistep procedure to ensure a selective reaction. Herein, sugar nucleotides were synthesized in one step using 2-chloro-1,3-dimethylimidazolinium chloride as the condensation reagent. The products were obtained in yields of 12-30%, and the yields were increased to 35-47% by the addition of a tuning reagent. NMR identification of the sugar nucleotides showed that mainly 1,2-<i>trans</i>-glycosides were present. The reported method represents a one-step route to sugar nucleotides from commercially available materials.
Cross-layer resource allocation for video streaming over OFDMA cognitive radio networks with imperfect cross-link CSI (2014)

In this paper, novel cross-layer radio resource allocation (RRA) algorithm is proposed in the context of Orthogonal frequency division multiple access (OFDMA)-based cognitive radio (CR) video application systems. User video quality and channel awareness are incorporated in the design, to exploit joint optimization of rate and power for secondary receivers (SRs), subject to minimum SR video quality and primary receiver (PR) interference threshold constraints. Firstly, the relationship between PR interference margin and power limits at the secondary transmitter (ST) is analytically derived. Then, to provide PRs with satisfactory quality of service (QoS), we propose a new probabilistic approach to mitigate the total imposed interference of the ST on PRs, considering imperfect ST to PR channel state information (CSI). The effect of PR interference limit violation probability, interference threshold, and error variance of imperfect CSI are evaluated using computer simulations. Results indicate that significant improvement in SR total video quality is achieved through our proposed algorithm over other state-of-the-art Non-Quality-Aware (NQA) designs in the literature. The enhanced performance was obtained whilst guaranteeing SR minimum quality and PR prescribed QoS constraints.
Safety, Tolerability, and Immunogenicity of the Novel Antituberculous Vaccine RUTI: Randomized, Placebo-Controlled Phase II Clinical Trial in Patients with Latent Tuberculosis Infection (2014)

ClinicalTrials.gov NCT01136161.
Outcomes after Transcatheter and Surgical Aortic Valve Replacement in Intermediate Risk Patients with Preoperative Mitral Regurgitation: Analysis of PARTNER II Randomized Cohort (2018)

BackgroundPreoperative mitral regurgitation (MR) in patients undergoing transcatheter (TAVR) and surgical aortic valve replacement (SAVR) has been studied in high-risk cohorts. This study examines the outcomes of preoperative MR (≥ moderate) in a larger, intermediate-risk cohort.MethodsThe Placement of Aortic Transcatheter Valves (PARTNER) 2A Trial randomized 2032 intermediate-risk patients with severe, symptomatic aortic stenosis to TAVR or SAVR. An ad-hoc analysis was performed on 1738 patients with baseline MR echocardiographic data. Patients were analyzed according to the degree of preoperative MR (≥ moderate versus ≤ mild).ResultsAt baseline, ≥ moderate MR was reported in 300 patients (17%). At 30 days, ≥ moderate MR had improved in 47% to ≤ mild. Thirty-day mortality was higher in SAVR patients with ≥ moderate MR (8.0 versus 3.5%; p = 0.01), but this difference was not seen in TAVR (2.7 vs. 3.1%; p = 0.78). At 2-years, the combined outcome of death (20.5 vs. 16.3%; p = 0.07), stroke (12.9 vs. 9.0%; p = 0.06), and rehospitalization (22.0 versus 17.4%; p = 0.06) was higher in the ≥ moderate MR (40.4 vs. 32.6%; p = 0.009), and similar between SAVR and TAVR (39.8 vs. 41.0%; p = 0.89).ConclusionsSignificant MR is prevalent in patients with severe AS and affects clinical outcomes after both TAVR and SAVR. SAVR patients with MR have high early risk, but the increased risk of death/stroke/rehospitalization becomes similar in both groups over time. Improvement in MR is common, especially in patients with lower ejection fraction and larger left-ventricular dimensions.
Pulse interference mitigation techniques for QPSK and QAM using Viterbi decoding (2010)

A severe spectrum shortage for wireless communication systems poses the spectrum overlapping and the interference problem with a significant performance degradation. To avoid this problem, it is essential to employ the techniques for interference mitigation. The goal of this paper is to investigate the performance of some interference mitigation techniques in the systems using Viterbi decoding, i.e., 1-norm metric, received power based limiting, puncturing and metric based limiting. These methods are compared from the view point of bit error rate (BER) obtained by computer simulations. Simulation results show the superiority of metric based limiting, which yields better BER performance.
Effect of GreenshellTM mussel on osteoarthritis biomarkers and inflammation in healthy postmenopausal women: a study protocol for a randomized double-blind placebo-controlled trial (2021)

Australian New Zealand Clinical Trials Registry (ANZCTR) ACTRN12620000413921p . Registration on 27 March 2020.
Value of Liver and Spleen Aspiration Biopsy in Malignant Diseases when these Organs Show no Signs of Involvement in Sonography (1983)

To determine whether an aspiration biopsy of liver and/or spleen is likely to reveal a clinically silent malignant infiltration, fine-needle aspiration biopsies were carried out in 180 patients with a diagnosed malignancy in whom neither the liver nor the spleen gave signs of involvement in sonography. Few, if any, findings were positive in patients with cancer or Hodgkin's disease. In non-Hodgkin lymphoma, about 25% of the biopsies were positive for malignancy or aroused suspicion of malignancy. We conclude that fine-needle aspiration biopsies of the liver and spleen may be of value in the clinical follow-up of non-Hodgkin lymphoma.
An Alternative Approach to Prescribing Sternal Precautions After Median Sternotomy, “Keep Your Move in the Tube” (2016)

Traditional sternal precautions, given to sternotomy patients as part of their discharge education, are intended to help prevent sternal wound complications. They vary widely but generally include arbitrary load and time restrictions (lifting no more than a specified weight for up to 12 weeks) and may prohibit common shoulder joint and shoulder girdle movements. Having observed the negative effects of restrictive sternal precautions for many years, our research team performed a series of studies that measured the forces exerted during various common activities and their relationship to the sternum. The results, though informative, led us to realize that the goal of identifying "the" appropriate load restriction to prescribe for sternotomy patients was futile. The alternative approach that we introduce applies standard kinesiological principles and teaches patients how to perform load-bearing movements in a way that avoids excessive stress to the sternum.
Capacity Definitions of General Channels with Receiver Side Information (2007)

We consider three capacity definitions for general channels with channel side information at the receiver, where the channel is modeled as a sequence of finite dimensional conditional distributions not necessarily stationary, ergodic, or information stable. The Shannon capacity is the highest rate asymptotically achievable with arbitrarily small error probability. The outage capacity is the highest rate asymptotically achievable with a given probability of decoder-recognized outage. The expected capacity is the highest expected rate asymptotically achievable with a single encoder and multiple decoders, where the channel side information determines the decoder in use. Expected capacity equals Shannon capacity for channels governed by a stationary ergodic random process but is typically greater for general channels. These alternative definitions essentially relax the constraint that all transmitted information must be decoded at the receiver. We derive equations for these capacity definitions through information density. Examples are also provided to demonstrate their implications.