gebhart/patrepeval huggingface dataset:
Modulation of surface-enhanced Raman spectra by depth selective excitation of embedded indium tin oxide nanoisland arrays (2011)

Embedded transparent conducting indium tin oxide (ITO) nanoisland arrays were prepared by pulsed laser deposition of ITO films on roughened Si templates and post-annealing to investigate the surface-enhanced Raman scattering activities. Considerable Raman enhancement of a rhodamine 6G probe during Ar + laser excitation was observed and modulated by the thickness of the ITO film due to the exponentially decaying field of the localized surface plasmon polaritons at the interface. Because the Raman-enhancing functional layer is protected at the ITO/Si interface, this system is reusable and also believed to be immune to contamination and other surface activities.
Supplementary Figure 2 from Phosphoproteomics Identifies Driver Tyrosine Kinases in Sarcoma Cell Lines and Tumors (2023)

&lt;p&gt;PDF file - 107K, Knockdown efficacy of siRNA&lt;/p&gt;
Low Band Gap Poly(thienylene vinylene)/Fullerene Bulk Heterojunction Photovoltaic Cells (2009)

Semicrystalline poly(3-hexyl-2,5-thienylene vinylene) (P3HTV) with a low band gap of 1.65 eV has been synthesized by acyclic diene metathesis polymerization and incorporated into bulk heterojunction (BHJ) organic solar cells. The polymer was thermally characterized by differential scanning calorimetry and thermogravimetric analysis and was blended with the electron acceptor methanofullerene [6,6]-phenyl C61-butyric acid methyl ester (PCBM) to make a light-harvesting charge-transfer thin film. The properties of P3HTV/PCBM blends were studied as a function of PCBM composition by wide-angle X-ray scattering, atomic force microscopy, transmission electron microscopy, UV−vis absorption spectroscopy, and charge-transport and photovoltaic measurements. The PCBM solubility limit, that is, the phase separation point, was estimated to be 50 wt % PCBM. The phase behavior of the blend was directly correlated with electrical transport behavior in a field-effect transistor testbed. At the phase separation point, charge carrier transport switches from hole only to ambipolar (both electron and hole) due to the formation of an electron-transporting percolating network of PCBM domains. BHJ solar cells were constructed with P3HTV films blended with varying weight fractions of PCBM. In these cells, spun-cast films of P3HTV/PCBM mixtures were sandwiched between poly(3,4-ethylene dioxythiophene)/poly(styrenesulfonate) (PEDOT/PSS)-coated ITO and Al electrodes. The best performance of polymer solar cells was observed at 50−60% PCBM, near the phase separation point at which power conversion efficiencies of 0.80−0.92% were measured under AM 1.5, 100 mW/cm2 illumination.
Enhancing Reproducibility and Nonlocal Effects in Film‐Coupled Nanoantennas (2018)

Abstract Nanopatch antennas based on the assembly of nanocubes are an appealing way to easily produce structures that feature very thin gaps between metals at a very low cost compared with other surface modification techniques. If these coatings are very good absorbers in the visible and near‐infrared range, they can also be of interest for reaching light confinement regimes where nonlocality arises strongly, or for designing molecular electronics junctions embedded in resonating cavities. Here both modeling and experimental realization of a nanocube assembly approach based on alkyldithiols molecules is proposed that enables a high reproducibility on the resonance position of the cavities, as well as gaps that are thinner than the usual 3 nm limit often reported in the literature, thus opening the way to experimental confirmation of nonlocal effects as well as new perspectives for molecular electronics.
3-dimensional digital reconstruction of the murine coronary system for the evaluation of chronic allograft vasculopathy (2015)

Chronic allograft vasculopathy (CAV) is a major mechanism of graft failure of transplanted organs in humans. Morphometric analysis of coronary arteries enables the quantitation of CAV in mouse models of heart transplantation. However, conventional histological procedures using single 2-dimensional sections limit the accuracy of CAV quantification. The aim of this study is to improve the accuracy of CAV quantification by reconstructing the murine coronary system in 3-dimensions (3D) and using virtual reconstruction and volumetric analysis to precisely assess neointimal thickness. Mouse tissue samples, native heart and transplanted hearts with chronic allograft vasculopathy, were collected and analyzed. Paraffin embedded samples were serially sectioned, stained and digitized using whole slide digital imaging techniques under normal and ultraviolet lighting. Sophisticated software tools were used to generate and manipulate 3D reconstructions of the major coronary arteries and branches. The 3D reconstruction provides not only accurate measurements but also exact volumetric data of vascular lesions. This virtual coronary arteriography demonstrates that the vasculopathy lesions in this model are localized to the proximal coronary segments. In addition, virtual rotation and volumetric analysis enabled more precise measurements of CAV than single, randomly oriented histologic sections, and offer an improved readout for this important experimental model. We believe 3D reconstruction of 2D histological slides will provide new insights into pathological mechanisms in which structural abnormalities play a role in the development of a disease. The techniques we describe are applicable to the analysis of arteries, veins, bronchioles and similar sized structures in a variety of tissue types and disease model systems. The virtual slide(s) for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/3772457541477230 .
Spin alignment and phase angles in<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mrow><mml:mmultiscripts><mml:mrow><mml:mi mathvariant="normal">C</mml:mi></mml:mrow><mml:mprescripts/><mml:mrow/><mml:mrow><mml:mn>12</mml:mn></mml:mrow><mml:mrow/><mml:mrow/></mml:mmultiscripts></mml:mrow></mml:math>+<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mrow><mml:mmultiscripts><mml:mrow><mml:mi mathvariant="normal">C</mml:mi></mml:mrow><mml:mprescripts/><mml:mrow/><mml:mrow><mml:mn>12</mml:mn></mml:mrow><mml:mrow/><mml:mrow/></mml:mmultiscripts></mml:mrow></mml:math>inelastic scattering (1983)

The spin alignment $A$ and the relative phase angle $\ensuremath{\beta}$ between the $m=+2 \mathrm{and} \ensuremath{-}2$ substates populated in $^{12}\mathrm{C}$+$^{12}\mathrm{C}$(${2}_{1}^{+}$) inelastic scattering were measured over a wide range of particle scattering angles ($53\ifmmode^\circ\else\textdegree\fi{}&lt;{\ensuremath{\theta}}_{\mathrm{c}.\mathrm{m}.}&lt;101\ifmmode^\circ\else\textdegree\fi{}$) and interaction energies ($15&lt;{E}_{\mathrm{c}.\mathrm{m}.}&lt;33$ MeV). Although the substate population parameters depend rather strongly on reaction angle, the angle-averaged alignment is markedly enhanced at energies where either broad or narrow maxima occur in $\ensuremath{\sigma}(E)$, at least below ${E}_{\mathrm{c}.\mathrm{m}.}=26$ MeV. Above that energy variations in the alignment become damped with respect to both bombarding energy and reaction angle. The relative phase $\ensuremath{\beta}(\ensuremath{\theta})$ is approximately linear in $\ensuremath{\theta}$ at most energies. For energies below ${E}_{\mathrm{c}.\mathrm{m}.}=26$ MeV corresponding to gross structure maxima in the inelastic cross sections, the measured dependence of the phase on reaction angle suggests that the reaction is dominated at these energies by individual entrance and exit channel partial waves $L$ and ${L}^{\ensuremath{'}}$, respectively, and that these are related by ${L}^{\ensuremath{'}}=L\ensuremath{-}2$. Thus a strongly aligned configuration can be associated with the maxima. At neighboring energies no evidence for such alignment was found. Calculations with the band-crossing, diffraction, distorted-wave Born approximation, and barrier-top models were compared to the measurements. None provide an adequate representation of the data.NUCLEAR REACTIONS $^{12}\mathrm{C}(^{12}\mathrm{C}, ^{12}\mathrm{C}\ensuremath{\gamma})$, ${E}_{\mathrm{lab}}=30\ensuremath{-}65$ MeV, ${\ensuremath{\theta}}_{\mathrm{c}.\mathrm{m}.}(^{12}\mathrm{C})=53\ifmmode^\circ\else\textdegree\fi{}\ensuremath{-}101\ifmmode^\circ\else\textdegree\fi{}$. Measured particle-$\ensuremath{\gamma}$ angular correlations; deduced magnetic substate alignments, phase angles; compared with model predictions.
Osteoprotegerin Predicts Progression of Chronic Heart Failure: Results From CORONA (2011)

OPG added no predictive information for the primary end point, but independently predicted WHF hospitalization in older patients with advanced chronic systolic HF of ischemic etiology. Clinical Trial Registration- URL: http://www.clinicaltrials.gov. Unique identifier: NCT00206310.
Piezoelectric pH sensors: AT-cut quartz resonators with amphoteric polymer films (1993)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPiezoelectric pH sensors: AT-cut quartz resonators with amphoteric polymer filmsJuan. Wang, Michael D. Ward, Richard C. Ebersole, and Robert P. FossCite this: Anal. Chem. 1993, 65, 19, 2553–2562Publication Date (Print):October 1, 1993Publication History Published online1 May 2002Published inissue 1 October 1993https://pubs.acs.org/doi/10.1021/ac00067a002https://doi.org/10.1021/ac00067a002research-articleACS PublicationsRequest reuse permissionsArticle Views364Altmetric-Citations28LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Diagnostic accuracy of enhanced liver fibrosis test for nonalcoholic steatohepatitis‐related fibrosis: Multicenter study (2022)

In Japan, the ELF test predicts NAFLD-related fibrosis from its early stages. The diagnostic ability of the ELF test was not inferior to that of other indices, and the combined values of ELF plus other indices were more accurate.
&lt;title&gt;Neural-network-based control of large structures&lt;/title&gt; (1993)

Adaptive control of spacecraft and large structures using Radial Basis Function (RBF) based Artificial Neural Networks (ANN) is investigated. The centers of approximation of the RBFs are allowed to be dynamic in order to provide persistent excitation and a small window of approximation. Both state and time based RBFs are investigated for their ability to identify unmodeled and persistent effects. Integral feedback of the attitude seems necessary, especially when the initial estimates are poor, to eliminate steady state errors for pointing applications. Examples of motion-to-rest as well as tracking maneuvers and vibration suppression are presented.
Metal‐Free Direct Asymmetric Aminoxylation of Aldehydes Catalyzed by a Binaphthyl‐Based Chiral Amine (2010)

And I'm free, metal-free fallin': A metal-free direct asymmetric aminoxylation of aldehydes with the oxoammonium salt 1, generated in situ from TEMPO and benzoyl peroxide (BPO), was found to be catalyzed by a binaphthyl-based secondary amine (S)-2. This method provides a new approach to bench-stable optically active α-aminoxy aldehydes as useful chiral building blocks. TMS=trimethylsilyl. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
Effects of static pressure on ultrasound-mediated transdermal delivery of tagging compounds into migratory fish (2000)

Research is currently being conducted with the US Fish and Wildlife Service investigating the use of ultrasound to enhance the transdermal delivery of tagging compounds into migratory fish. There is a need for noninvasive, low-cost, and efficient methods of tagging large numbers of fish in order to follow their migratory patterns. Current methods require long periods of immersion that can create health problems and are limited in the amount of uptake of the compound. Previously reported research [J. A. Clark et al., J. Acoust. Soc. Am. 101, 3138(A) (1997)] showed cavitation levels of ultrasound (2–3 W/cm2) at 71 kHz significantly enhanced the transdermal delivery of the tagging compound calcein (fluorexon) into rainbow trout (Salmo gairdneri) yoke-sac larvae. However, attempts to repeat the experiment at higher altitudes revealed that static pressure critically affected the results. A further investigation into the effect of static pressure on the enhanced delivery of calcein by ultrasound into rainbow trout is reported here. A system for generating controlled doses of cavitation level ultrasound at various levels of ambient pressure will be described. The effect of static pressure on calcein uptake will be shown via fluorescent microscopy.
Data Security Architecture Considerations for Telemetry Post Processing Environments (2017)

Telemetry data has great value, as setting up a framework to collect and gather it involve significant costs. Further, the data itself has product diagnostic significance and may also have strategic national security importance if the product is defense or intelligence related. This potentially makes telemetry data a target for acquisition by hostile third parties. To mitigate this threat, data security principles should be employed by the organization to protect telemetry data. Data security is in an important element of a layered security strategy for the enterprise. The value proposition centers on the argument that if organization perimeter/internal defenses (e.g. firewall, IDS, etc.) fail enabling hostile entities to be able to access data found on internal company networks; they will be unable to read the data because it will be encrypted. After reviewing important encryption background including accepted practices, standards, and architectural considerations regarding disk, file, database and application data protection encryption strategies; specific data security options applicable to telemetry post processing environments will be discussed providing tangible approaches to better protect organization telemetry data.
Association Between Use of Multiple Classes of Antibiotic in Infancy and Prevalence of Allergic Disease in Childhood. (2020)

PURPOSE Antibiotic administration negatively impacts the microbiome by decreasing bacterial diversity which has shown to correlate with allergic disease. Antibiotic stewardship is especially important in the infant population as microbiome alteration may impact a child for the remainder of their life. Exposure to multiple classes of antibiotic may amplify the impact on the gut biome and may increase the likelihood of allergy, strengthening a causation hypothesis. The purpose of this study is to determine whether exposure to increasing number of antibiotic classes in infancy increases risk of developing allergic disease in early childhood. METHODS …
Wireless magnetic micro-machine of planar structure with magnetic thin film (2005)

Magnetic micro-machines are driven by a magnetic field. They require no power supply cables, no batteries, and no controlling systems on the body of the machine. In previous studies, we examined the swimming properties of spiral-type magnetic micro-machines. The micro-machine was composed of a bulk magnet and a spiral structure. To reduce the size of the bulk magnet is not easy. By using magnetic thin film, however, the size of magnetic micro-machines can be reduced to several dozen micro millimeters. At this size, they can be produced using a fine processing technology. In this paper, we fabricated the magnetic micro-machine of planar structure with magnetic thin film. We examined about the performance the micro-machine in the liquid.
Abstract B66: Blockade of PD-1 signaling in tumor-associated dendritic cells results in compensatory IL-10 release maintaining immune suppression in ovarian cancer microenvironments. (2016)

Abstract PD-1 and PD-L1 form a major inhibitory axis that acts to suppress tumor-rejecting effector responses. In addition to its expression and inhibitory functions in T and B cells, PD-1 has also been shown to be expressed on and hence impact the functions of cells of innate arm, such as dendritic cells (DCs), primarily at the tumor site but not in the periphery. Our aim in this study was to identify tumor-associated factor(s) responsible for PD-1 regulation on DCs and investigate how DCs in the tumor microenvironment respond to anti-PD-1-based immunotherapy. Both bone marrow-derived dendritic cells (BMDCs) as well as murine ovarian tumor ascites-derived DCs were used in the studies. Using in vitro cultures, we show that the cytokine IL-10; which is expressed in abundance in many malignancies including ovarian cancer, is potent regulator of PD-1 expression on DCs. Based on inhibition and siRNA knockdown studies; we show that IL-10 mediated PD-1 expression depends on STAT3 activation. Treatment of DCs with IL-10 also led to an increase in expression of PD-L1 on surface of DCs as well as an increase in release of soluble PD-L1. Antibody-mediated blockade of PD-1 on DCs led to greatly increased production of IL-10 (&amp;gt; 4 fold) in cultures in vitro. Furthermore, treatment of tumor bearing mice with anti-PD-1 antibody led to a significant increase of IL-10 in ascites (&amp;gt; 6 fold) and periphery (&amp;gt; 4 fold). This compensatory release of IL-10 correlated with a further increase in PD-1 expression on DCs both in vitro and in vivo. In in vivo studies, while the blockade of PD-1 or IL-10 neutralization as monotherapy were ineffective, blockade of PD-1 and IL-10 neutralization as combination therapy augmented the anti-tumor response in ovarian tumor bearing mice; leading to a decrease in tumor growth and a significant increase in survival. These results show that the IL-10 and PD-1 pathways intersect with DCs in the tumor microenvironment. PD-1 blockade on DCs leads to compensatory release of IL-10 resulting in the maintenance of immunosuppression, and a combination regimen of PD-1 blockade and IL-10 neutralization has therapeutic benefit in ovarian tumors. These results serve as catalyst to explore the feasibility/efficacy of exploiting these targets in clinical settings for treatment of human ovarian cancer. Citation Format: Purushottam Lamichhane, Lavakumar Karyampudi, Barath Shreeder, James Krempski, Deborah Bahr, Matthew Block, Keith Knutson. Blockade of PD-1 signaling in tumor-associated dendritic cells results in compensatory IL-10 release maintaining immune suppression in ovarian cancer microenvironments. [abstract]. In: Proceedings of the AACR Special Conference on Advances in Ovarian Cancer Research: Exploiting Vulnerabilities; Oct 17-20, 2015; Orlando, FL. Philadelphia (PA): AACR; Clin Cancer Res 2016;22(2 Suppl):Abstract nr B66.
Characterization of Cerebral Infarction by Multicomponent Analysis of Transverse Magnetization Decay Curves (1992)

Bi-exponential analysis of TDCs may have diagnostic use as a more sensitive indicator of cerebral infarction than mono-exponential analyses.
Untersuchungen über Isopolywolframate (1965)

Evidence for the presence of OH-groups in solid alkaline meta-, para-B- and ψ-metatungstates is given by infrared and 1 H-nuclear magnetic resonance spectra. The three tungstates have to be formulated as M I 6 [W 12 O 38 (OH) 2 ] • x H 2 O, M I 10 [ W 12 O 36 (OH) 10 ] • x H 2 O and M I 12 [W 24 O 72 (OH) 12 • x H 2 O respectively. The mole masses of the different polytungstates were calculated from the speed of sedimentation in the ultracentrifuge. In the concentration range covered, 10 -2 &amp;gt; Cwo 4 2 Ⓡ &amp;gt; 10 -4 , the same ions occur as in the solid state. The effect of aging and heating on polytungstate solutions was studied by means of pH-measurements, by pH-titrations, by ultraviolet spectra, and by the T-jump relaxation method. The para· tungstate-A-ion [W 6 20 (OH)] 5 ® formed upon acidification of a H®/WO 4 2 ® = 1,167 ratio solution according to the equation 6 WO 4 2 ® + 7 H® ⇄ [W 6 O 20 (OH)] 5 ® [log K ∼ 57,5] is in equilibrium with the paratungstate-B-ion [W 12 O 36 (OH) 10 ] 10® . In a solution of solid paratungstate-B the same equilibrium is attained. Upon aging and, more rapidly, by heating the para-A-/para-B-solution in equilibrium changes to -ψ-meta and finally to metatungstate. During this process an increase in the pH-value is observed due to the reduced acidity of the para-B-ion and to the enhanced condensation of para-(probably of para-B only) to ψ-meta and further to metatungstate. Upon acidification to the H®/WO 4 2® ratio Ρ=1,50 the ψ-meta-ion is formed quantitatively which changes to the metaion slowly. For P=1,50 characteristic ultraviolet absorption bands indicate the formation of a new polytungstate species [ W 12 O x (OH) y ] 72 — ( 2x+y ), called polytungstate-Y. It changes rapidly and quantitatively to ψ-meta-tungstate. In aged solutions with P ≧ 1,50 only the meta-ion is found. In solutions with Ρ &amp;lt; 1,50 WO 4 2e , polytungstate-X-ions were found besides meta-ions. The relative concentration of these ions as a function of Ρ is given. The so-called X-species is probably the para-B-ion. By means of a scheme, the reactions upon acidification of a monotungstate solution are illustrated.
Data-based optimal estimation of frequency bias: The case of Southwest Power Pool (2023)

In this paper, we introduce a method to optimally estimate time-varying frequency bias. Current industry practice is to assume that frequency bias is changing only on annual basis. We suggest that this improved time-dependent bias estimate can be used to reduce the cost of frequency regulation needed to meet industry standards requested by the North American Electric Reliability Corporation (NERC). Optimization of time-varying frequency bias is posed as a parameter estimation (calibration) problem whose implementation utilizes online system measurements. It is further shown how this result can be used to estimate intra-dispatch load deviations. This knowledge is needed to estimate more accurately regulation reserve needed, and to therefore reduce overall regulation cost. Methods can be introduced to give incentives to demand response to participate in frequency regulation. Overall, we show the importance of incorporating knowledge of physics-based models for data-enabled parameter estimation of physical systems.