gebhart/patrepeval huggingface dataset:
Unsteady 3D Rarefied Flow Solver Based on Boltzmann-ESBGK Model Kinetic Equations (2011)

Formulation and verification of unsteady rarefied flow solver based on BoltzmannESBGK equations in arbitrary three-dimensional geometries is presented. The solver is based on the finite volume method in physical space and the discrete ordinate method in velocity space with an implicit time discretization. Verification is carried out for an unsteady approach to equilibrium, a steady one-dimensional Couette flow and a two-dimensional quasi-steady gas damping problem. Finally, the application of the full 3D parallel solver is considered to simulate unsteady microscale gas damping in a micro-electro-mechanical system switch.
Wind profiler installed in Antarctica (1993)

A VHF (50 MHz) wind profiler was installed in Antarctica at the Peruvian Base “Machu Picchu” on King George Island from January 21 to 26. The wind profiler will provide a first look at atmospheric dynamics over the region. The profiler—the first of its kind in Antarctica—is a National Science Foundationsponsored cooperative project of the University of Colorado, the Geophysical Institute of Peru, the University of Piura (Peru), and the Peruvian Navy. This venture was also greatly facilitated by Peru's Comision Nacional de Asuntos Antartidos and Consejo Nacional de Ciencias y Tecnologia, with additional logis tics support provided by the Argentinean Navy and the Uruguayan Air Force.
Abstract 4291: A novel image-based cytometry method for autophagy detection in living cells (2014)

Abstract Autophagy is an important cellular catabolic process that plays a variety of important roles, including maintenance of the amino acid pool during starvation, recycling of damaged proteins and organelles, and clearance of intracellular microbes. Currently employed autophagy detection methods include fluorescence microscopy, biochemical measurement, SDS-PAGE, and Western blotting, but they are time-consuming, labor-intensive, and require much experience for accurate interpretation. More recently, development of novel fluorescent probes have allowed the investigation of autophagy via standard flow cytometry. However, flow cytometers remain relatively expensive and require a considerable amount of maintenance. Previously, image-based cytometry has been shown to perform automated fluorescence-based cellular analysis comparable to flow cytometry. In this study, we developed a novel method using the Cellometer image-based cytometer in combination with Cyto-ID® Green dye for autophagy detection in live cells. The method is compared to flow cytometry by measuring macroautophagy in nutrient-starved Jurkat cells. Results demonstrate similar trends of autophagic response, but different magnitude of fluorescence signal increases, which may arise from different analysis approaches characteristic of the two instrument platforms. The possibility of using this method for drug discovery applications is also demonstrated through the measurement of dose-response kinetics upon induction of autophagy with rapamycin and tamoxifen. The described image-based cytometry/fluorescent dye method should serve as a useful addition to the current arsenal of techniques available in support of autophagy-based drug discovery relating to various pathological disorders. Citation Format: Leo Li-Ying Chan, Dee Shen, Alisha R. Wilkinson, Wayne Patton, Ning Lai, Eric Chan, Dmitry Kuksin, Bo Lin, Jean Qiu. A novel image-based cytometry method for autophagy detection in living cells. [abstract]. In: Proceedings of the 105th Annual Meeting of the American Association for Cancer Research; 2014 Apr 5-9; San Diego, CA. Philadelphia (PA): AACR; Cancer Res 2014;74(19 Suppl):Abstract nr 4291. doi:10.1158/1538-7445.AM2014-4291
Supplementary Figure 4 from CCN6 Modulates BMP Signaling via the Smad-Independent TAK1/p38 Pathway, Acting to Suppress Metastasis of Breast Cancer (2023)

&lt;p&gt;PDF file, 90K, Co-localization of CCN6 and BMP4 in clinical samples of breast cancer.&lt;/p&gt;
Matrix-assisted laser desorption/ionization mass spectrometric analysis of polysulfated-derived oligosaccharides using pyrenemethylguanidine (2008)

A better understanding of the biological roles of carbohydrates requires the use of tools able to provide efficient and rapid structural information. Unfortunately, highly acidic oligomers-such as polysulfated oligosaccharides-are very challenging to characterize because of their high polarity, structural diversity, and sulfate lability. These features pose special problems for matrix-assisted laser desorption/ionization mass spectrometric (MALDI-MS) analysis because polysulfated carbohydrates exhibit poor ionization efficiency and usually do not produce any signal. The present report demonstrates how MALDI-MS can be used to derive structural and compositional information from pure and mixed fractions of polysulfated oligosaccharides. Indeed, pyrenemethylguanidine (pmg, a derivatizing agent and ionization efficiency enhancer) was used for the analysis of di- to decasaccharides, carrying from two to nine sulfate groups. The method is applied to various highly sulfated chondroitin and carrageenan oligosaccharides as well as to the analysis of mixtures of compounds. In the mass spectra, the observation of a unique pmg-complexed ladder of peaks in both ionization modes allows an easy and rapid determination of both the number of sulfate groups carried by the analyte and its molecular weight. Moreover, we have developed a software tool for the rapid and automatic structural elucidation of carrageenans based on the mass spectra obtained.
Monoclonal antibodies to subgroup 1 rotavirus (1983)

Subgroup 1-specific monoclones were analyzed and used successfully in an enzyme-linked immunosorbent assay to recognize certain subgroup 1 rotaviruses.
Language learning in multi-agent systems (2005)

We present the problem of learning to communicate in decentralized and stochastic environments, analyzing it formally in a decision-theoretic context and illustrating the concept experimentally. Our approach allows agents to converge upon coordinated communication and action over time.
Impact of Stopping Voltage and Hopping Conduction on the Oxygen Vacancy Concentration of Multi-Level HfO<sub>2</sub>-Based Resistive Switching Devices (2020)

A multi-level state HfO <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</inf> -based resistive switching model is reported, where the increase in stopping voltage (V <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">stop</inf> ) and thus activation energy (E <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">AC</inf> ) is attributed to the depletion of oxygen vacancy (V <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">o</inf> ) concentration (n <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">c</inf> ) during reset. Hopping conduction fittings also indicated a depletion of n <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">c</inf> due to an increase of V <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">stop</inf> as shown by an increase of trap-to-trap distance (a) and trap energy (ϕ <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">T</inf> ).
ChemInform Abstract: POLYAZA CAVITY SHAPED MOLECULES. 2. ANNELATED DERIVATIVES OF 2,2′‐BIQUINOLINE E AND THE CORRESPONDING N‐OXIDES (1985)

Abstract Aus 2‐Aminobenzaldehyd (I) und den 1,2‐Diketonen (II) werden die Bis‐chinoline (III) und daraus deren N‐Oxide (V) und (VI) hergestellt.
Over-the-Air Integrated Sensing, Communication, and Computation in IoT Networks (2022)

To facilitate the development of Internet of Things (IoT) services, tremendous IoT devices are deployed in the wireless network to collect and pass data to the server for further processing. Aiming at improving the data sensing and delivering efficiency, the integrated sensing and communication (ISAC) technique has been proposed to design dual-functional signals for both radar sensing and data communication. To accelerate the data processing, the function computation via signal transmission is enabled by over-the-air computation (AirComp), which is based on the analog-wave addition property in a multi-access channel. As a natural combination, the emerging technology namely over-the-air integrated sensing, communication, and computation (Air-ISCC) adopts both the promising performances of ISAC and AirComp to improve the spectrum efficiency and reduce latency by enabling simultaneous sensing, communication, and computation. In this article, we provide a promptly overview of Air-ISCC by introducing the fundamentals, discussing the advanced techniques, and identifying the applications.
Process Optimization of CoSi<sub>2</sub> Formation on P-Doped Poly-Si by Hot Wall-Based Rapid Thermal Annealing (2015)

To achieve low resistivity contacts, the effect of annealing temperature and time on the resulting resistivity of CoSi 2 contacts with P-doped poly-Si was investigated using a single wafer furnace-based (hot wall) rapid thermal annealing (RTA) system. The hot wall RTA resulted in significantly (&gt;20%) lower sheet resistance (Rs) from the equivalent RTA process using conventional tungsten halogen lamp-based (cold wall) RTA systems over a very wide process window. Dopant (P) depth profiling results by secondary ion mass spectroscopy (SIMS) revealed that the P atoms in the CoSi 2 film and at the CoSi 2 /P-doped poly-Si interface, redistribute very differently under different RTA conditions. The CoSi 2 formation process was optimized utilizing characteristics of P pile-up near the CoSi 2 /P-doped poly-Si interface to suppress P depletion from the P-doped poly-Si layer.
Social care (2000)

David Lane analyses the current differentiation between nursing and residential homes and looks forward to a new way of working in the future.
Monitoring Particle Sedimentation in Conductive Suspensions with Moving Electrode Impedance Spectroscopy (2019)

We devised a method to monitor the sedimentation of particles from conductive solutions by means of moving electrode electrochemical impedance spectroscopy. Measuring impedance spectra at different electrode spacings allows an isolated view on the electrolyte properties while simultaneously studying sedimentation processes. We present an experimental setup and propose application, for instance, to monitor crystallization processes in ionic liquids for the use of zeolite synthesis.
PO-259 Identification of a clinically meaningful site-specific steroid roadmap in prostate cancer (2018)

ABSTRACT Introduction In prostate cancer the genotype of the tumour does not always predict clinical behaviour and disease aggressiveness after castration therapy. Additional factors might be important. Here we hypothesise that there is a site-specific steroid profile roadmap after castration that is of clinical significance. Material and methods Steroid profiles in blood plasma (BP) and bone marrow aspirate plasma (BMA) from 120 castrated patients with prostate cancer were evaluated with mass spectrometry. We studied the steroid ligand-receptor interactions in prostate cancer adrenal metastases (PCAM) because they represent a steroid-rich environment. Adrenalectomy specimens from 3 castrated patients with PCAM were analysed. Results and discussions It is known that normally BP/Adrenal vein plasma testosterone (T) concentration ratio is approximately 1:1 and cortisol (C) ratio is roughly1:3. We measured similar T levels in BP and BMA. The levels of C were significantly lower in BMA compared to BP. Our data suggest that T levels are uniform but there is a C concentration gradient between the different compartments. Cortisol acts through GR and in the presence of T is a partial AR inhibitor. All PCAM samples had functional androgen receptor (AR) (wild-type (wt), no copy number changes) and glucocorticoid (GR), but no progesterone receptor (PR). No DHT was detected. Patient 1 tumour was able to synthesise T and had above castrate intra-tumoral T levels. The tumour lacked enzymes to synthesise, but was able to catabolize C. The levels of C were within the normal BP range. Gene expression of AR was normal. Patient 2 and 3 samples had castrate T and high C levels (3-fold BP), but AR gene expression was remarkably high. All patients had PTEN and RB deletions, while patients 2 and 3 had mutant (m) p53. Addition of 40 ng/dl T increased growth in vitro in a xenograft PCAM model (propagated in matrigel) derived from patient 1. When C was concomitantly added at high levels such as those in patients 2 and 3, PCAM growth returned to baseline (no steroids), suggesting that almost all T or C activity were lost. Moreover, proliferation in VCAP cells (High AR/GR+) decreased when high C was added in low T, but remained well above baseline, generating the hypothesis that this steroid combination mostly inhibits AR/GR tumours with non-amplified AR (e.g. early in castration). Conclusion There is a clinically meaningful site-specific steroid roadmap. The PCAM steroid profile may serve as a useful model to elucidate tumour interactions with the steroid environment.
Application‐specific integrated filters for color‐sequential microdisplay‐based projection applications (2001)

Abstract— Application‐specific integrated filters (ASIFs), based on a unique holographic polymer‐dispersed liquid‐crystal (H‐PDLC) material system offering high efficiency, fast switching, and low switching voltage, are being developed for microdisplay‐based projection applications. The basic properties and key benefits of ASIFs in projection displays are reviewed.
Effect of Geometry on CVI with RF Heating (2010)

A comprehensive finite-element model is used to examine the effects of preform and induction-coil geometry on radio-frequency assisted chemical vapor infiltration of carbon preforms. Densification occurs axially in an “inside-out” manner in long cylindrical preforms heated by a helical induction-coil with constant input power. Entrapped porosity is formed in the center of the preform. As the height to diameter ratio of the cylinder is decreased, the densification pattern becomes radial in nature directed from the edges to the center of the preform. Entrapped porosity is then formed near the radial edges of the preform. The densification behavior is also sensitive to the geometry of the induction-heating coil. Schemes for tailoring coil geometry and operating parameters are developed for the densification of conical-shaped carbon preforms.
Very pre‐term infants' behaviour at 1 and 2 years of age and parental stress following basic developmental care (2007)

This study explored the effects of basic developmental care on the behaviour of very pre‐term infants and parental stress at 1 and 2 years of corrected age. A randomized controlled trial was done to compare basic Developmental Care (standardized nests and incubator covers) and controls (standard care). Parents of infants born &lt;32 weeks of gestation completed questionnaires measuring child behaviour and parental stress at 1 year ( N = 139) and 2 years ( N = 133) of the child's age. Parental stress was measured using the Nijmegen Parenting Stress Index and child behaviour was measured using the Infant–Toddler Social and Emotional Assessment (ITSEA) and the Child Behaviour Checklist 2–3. At 1 year of age, children in the basic developmental care group had significantly higher behaviour scores on the total competence domain ( p = .009) and the competence subscale mastery motivation ( p = .002) of the ITSEA questionnaire, meaning that the infants showed more curiosity, persistence, obedience and enjoyment with small accomplishments. No significant effects were found on problem behaviour or parenting stress. We conclude that introducing a basic form of developmental care in the neonatal intensive care unit has a positive influence on the child's competence behaviour at 1 year of age.
Three steps of Neuron Network classification for EMG-based Thai tones speech recognition (2013)

In order to overcome the problem existing in original speech recognition (e.g. noise interruption and private data loss), many researchers have investigated to deal with these problems. Electromyography (EMG) from the muscles producing speech was used to replace a voiced signal. Similarly, we aim to develop EMG speech recognition based on Thai language. Tone is the important characteristic of this language. Hence, Thai tone classification is the first work that was explored. This paper proposes the new technique that can classify five Thai tones for EMG-based Thai speech recognition. This method can overcome the limitation of our previous work that we can classify only two tones. EMG was captured from six positions of the strap muscles and facial muscles while a volunteer was uttering 21 Thai isolated words and five tones of each word (total 105 words). The 68 EMG features were calculated, and RES index was used to evaluate clustering capability of each feature. Top five features that have high value of RES index were selected. Neuron Network (NN) was used for tone classification. We found that Modify Mean Absolute Value 2 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">nd</sup> type (MMAV2) is the best features. It yielded an accuracy rate of 56.2% for five Thai tones classification. However, it is not enough for our work. In order to improve the accuracy rate, the three steps of NN Classification was proposed. This technique is the series of three networks of NN classifier. Each network will classify different tones, and use distinct features. We obtained an accuracy rate of 80% for five Thai tones classification from this technique.
Single microbubble measurements of temperature dependent viscoelastic properties (2017)

Lipid-coated microbubbles are being researched as agents for ultrasound imaging and ultrasound-assisted drug delivery. It is well known that lipid shell composition of a microbubble affects the acoustic response. However, the effect of temperature on lipid shell viscoelasticity has not yet been fully established. The goal of this study was to determine the effect of temperature on the viscoelastic response of individual lipid-coated microbubbles.
Rift Valley Fever Virus Vaccine Lacking the NSs and NSm Genes Is Safe, Nonteratogenic, and Confers Protection from Viremia, Pyrexia, and Abortion following Challenge in Adult and Pregnant Sheep (2011)

Rift Valley fever virus (RVFV) is a mosquito-borne human and veterinary pathogen causing large outbreaks of severe disease throughout Africa and the Arabian Peninsula. Safe and effective vaccines are critically needed, especially those that can be used in a targeted one-health approach to prevent both livestock and human disease. We report here on the safety, immunogenicity, and efficacy of the ΔNSs-ΔNSm recombinant RVFV (rRVFV) vaccine (which lacks the NSs and NSm virulence factors) in a total of 41 sheep, including 29 timed-pregnant ewes. This vaccine was proven safe and immunogenic for adult animals at doses ranging from 1.0 × 10(3) to 1.0 × 10(5) PFU administered subcutaneously (s.c.). Pregnant animals were vaccinated with 1.0 × 10(4) PFU s.c. at day 42 of gestation, when fetal sensitivity to RVFV vaccine-induced teratogenesis is highest. No febrile reactions, clinical illness, or pregnancy loss was observed following vaccination. Vaccination resulted in a rapid increase in anti-RVFV IgM (day 4) and IgG (day 7) titers. No seroconversion occurred in cohoused control animals. A subset of 20 ewes progressed to full-term delivery after vaccination. All lambs were born without musculoskeletal, neurological, or histological birth defects. Vaccine efficacy was assessed in 9 pregnant animals challenged at day 122 of gestation with virulent RVFV (1.0 × 10(6) PFU intravenously). Following challenge, 100% (9/9) of the animals were protected, progressed to full term, and delivered healthy lambs. As expected, all 3 sham-vaccinated controls experienced viremia, fetal death, and abortion postchallenge. These results demonstrate that the ΔNSs-ΔNSm rRVFV vaccine is safe and nonteratogenic and confers high-level protection in sheep.
Upstream Data Architecture and Data Governance Framework for Efficient Integrated Upstream Workflows and Operations (2017)

Abstract Integrated Upstream workflows require efficient sharing of data across business disciplines involving planning studies, development, operations to carry our effective monitoring, surveillance of their reservoir and operations for better management of reservoir and production optimization. ADNOC requires quality, complete and timely multi-disciplinary data from its operating companies for efficiently monitoring its assets and provide informed directions. An Integrated Data Architecture and Data Governance Framework is being established to enable efficient deliver data to execute integrated upstream workflows in a multi-disciplinary and multi-vendor technology environment. The framework facilitates to standardize, streamline G&amp;G, reservoir, production, operations data and processes, and enables integrated reservoir management workflows and inter disciplinary collaboration in a multivendor technology environment. The Framework provides guidance and best practices to build common data architecture foundation for integrated upstream workflows. The framework enables to efficiently govern the data across its lifecycle and makes the relevant business team and data custodians to take responsibility to validate, store and deliver static and real-time data in a timely manner for Integrated Upstream workflows. The framework components form a key foundation element for efficient integrated workflows towards realizing integrate operations, closed loop optimization, full benefit of Smart Field Investment.
Degree-Day Prediction Models for the Flight Phenology of Western Bean Cutworm (Lepidoptera: Noctuidae) Assessed with the Concordance Correlation Coefficient (2015)

Western bean cutworm, Striacosta albicosta (Smith) (Lepidoptera: Noctuidae), is a native, univoltine pest of corn and dry beans in North America. The current degree-day model for predicting a specified percentage of yearly moth flight involves heat unit accumulation above 10°C after 1 May. However, because the moth's observed range has expanded into the northern and eastern United States, there is concern that suitable temperatures before May could allow for significant S. albicosta development. Daily blacklight moth catch and temperature data from four Nebraska locations were used to construct degree-day models using simple or sine-wave methods, starting dates between 1 January and 1 May, and lower (-5 to 15°C) and upper (20 to 43.3°C) developmental thresholds. Predicted dates of flight from these models were compared with observed flight dates using independent datasets to assess model performance. Model performance was assessed with the concordance correlation coefficient to concurrently evaluate precision and accuracy. The best model for predicting timing of S. albicosta flight used simple degree-day calculations beginning on 1 March, a 3.3°C (38°F) lower threshold, and a 23.9°C (75°F) upper threshold. The revised cumulative flight model indicated field scouting to estimate moth egg density at the time of 25% flight should begin when 1,432 degree-days (2,577 degree-days °F) have accumulated. These results underscore the importance of assessing multiple parameters in phenological models and utilizing appropriate assessment methods, which in this case may allow for improved timing of field scouting for S. albicosta.