gebhart/patrepeval huggingface dataset:
New acoustical techniques for measuring spatial properties in concert halls (2006)

The paper describes a new, hybrid method for measuring the spatial/temporal transfer function of a concert hall, which employs both a binaural probe and a B-format microphone.

It is shown how these two techniques can be complementary, both in terms of determination of objective parameters and for performing audible reconstructions (auralization).

The main advantage of this measurement method is that it makes it possible to conduct comparative listening tests with virtually zero delay for switching.

Consequently, the short-time perceptual memory of the subjects is employed, allowing for the detection of very subtle differences, which are not perceivable in normal listening tests, due to the excessive time delay between the presentation of the stimuli
Supplementary Table S3 from Salivary Gland Cancer Patient-Derived Xenografts Enable Characterization of Cancer Stem Cells and New Gene Events Associated with Tumor Progression (2023)

&lt;p&gt;Excel file will all damaging mutations called by Exome-seq analysis of SGC tumor tissue.&lt;/p&gt;
Effect of packaging on dielectric charging in RF MEMS capacitive switches (2009)

A novel technique was used to evaluate the effectiveness of packaging in maintaining a dry ambient atmosphere for electrostatically actuated RF MEMS capacitive switches and in preventing the charging of the dielectric surface after prolonged operation. It was found that as-packaged switches exhibited different degrees of surface charging, probably due to different amounts of moisture inadvertently sealed in the essentially hermetic packages. However, after the switches were delidded and baked dry, all switches showed minimum surface charging. The results imply that the switches can have consistently long lifetimes by improving the yield of the packaging process.
Gastrointestinal motility disorders. (1996)

A careful history can localize gastrointestinal motility disorders and suggest appropriate diagnostic tests. Dysphagia, odynophagia, heartburn and reflux have esophageal origins. The same symptoms occur in achalasia, a classic motor disorder of the lower esophageal sphincter, which can be diagnosed by barium swallow, endoscopy and esophageal motility studies. Nausea, vomiting, anorexia, bloating and abdominal pain are symptoms of motor disorders of the stomach and small intestine. When these symptoms are accompanied by unexplained right upper quadrant pain, elevated liver enzyme levels and unexplained recurrent pancreatitis, the diagnosis of impaired biliary motility is suggested. Colorectal motility disorders may present as abdominal pain, diarrhea, constipation and/or fecal incontinence. If symptoms do not resolve with dietary changes and appropriate medications and the anatomy is normal on lower gastrointestinal studies, colorectal motility studies may be indicated.
Cloud-Based Information Technology Framework for Data Driven Intelligent Transportation Systems (2013)

We present a novel cloud based IT framework, CloudTrack, for data driven intelligent transportation systems. We describe how the proposed framework can be leveraged for real-time fresh food supply tracking and monitoring. CloudTrack allows efficient storage, processing and analysis of real-time location and sensor data collected from fresh food supply vehicles. This paper describes the architecture, design, and implementation of CloudTrack, and how the proposed cloud-based IT framework leverages the parallel computing capability of a computing cloud based on a large-scale distributed batch processing infrastructure. A dynamic vehicle routing approach is adopted where the alerts trigger the generation of new routes. CloudTrack provides the global information of the entire fleet of food supply vehicles and can be used to track and monitor a large number of vehicles in real-time. Our approach leverages the advantages of the IT capabilities of a computing cloud into the operations and supply chain.
Therapieansätze für erbliche Netzhauterkrankungen: von den Genen bis zum Chip (2014)

Different strategies for the treatment of inherited photoreceptor degeneration are currently being investigated, with each of these approaches facing specific challenges. Gene therapy, for instance, may be feasible only for genetically well-defined pathologies. However, inherited retinal disorders are genetically highly heterogeneous and early onset disorders may restrict the therapeutic window. The majority of currently developed molecular approaches aim at the reconstitution of physiologically important functions in RPE and photoreceptor. Neuroprotection attempts to prolong cell survival and proper function via sustained delivery systems that fulfil a long-term dynamic reservoir function for therapeutic neuroprotective compounds. Cell-based approaches include replacement strategies such as cell transplantation, the implantation of prosthetic devices or optogenetics. They aim at replacing lost neurosensory functions of the retina. This short review aims at providing an insight into current therapeutic strategies and future treatment options for retinal disorders. Pharmacological and nutritional support strategies are only briefly discussed as we focus here on molecular and prosthetic therapeutic approaches.
Harvesting MDT data: Radio environment maps for coverage analysis in cellular networks (2013)

Despite the remarkable progress in radio access technology to support the rapidly increasing wireless data demand, coverage analysis remains as one of the indispensable topics on which mobile operators still need innovations, above all, in terms of operational efficiency together with performance. Manual coverage detection and prediction is an inefficient and costly task. In this paper we show how Radio Environment Maps (REMs) developed as part of the research on cognitive wireless networks can be used as a basis for a powerful coverage estimation and prediction solution for present-day cellular networks. Applying powerful spatial interpolation techniques on the information coming from location-aware devices, REMs provide a realistic and remote representation of the ground-truth. The proposed approach automatically identifies the number, location and shape of the existing coverage holes and therefore constitutes a perfect example of a novel application of the Cognitive Radio concept on next generation cellular networks. Results on urban and rural environments show that the use of REM brings promising gains in coverage hole detection and prediction with respect to the case where only measurements are used.
Redox divergent conversion of a [2]rotaxane into two distinct degenerate partners with different shuttling dynamics (2012)

The submolecular translational movement in novel hydrogen-bonded [2]rotaxanes containing benzylic amide macrocycles and two azo/hydrazodicarboxamide binding sites was analyzed by dynamic NMR spectroscopy. The results show that the activation free energies of the macrocycle shuttling in these systems depend on the oxidation level of both nitrogen-based binding sites embedded in the thread; the shuttling motion being more rapid in [2]rotaxanes at the lower oxidation level bis(hydrazo)-based rotaxanes. Moreover, by means of a fully controllable chemical switching, these two-station [2]rotaxanes are able to swap over three different dynamic states, which differ in macrocycle shuttling velocity: a) faster in a bis(hydrazo) [2]rotaxane, the lower oxidation state; b) moderate in a bis(azo) [2]rotaxane, the higher oxidation state; and c) practically stopped at the azodicarboxamide station of an azo/hydrazo [2]rotaxane, the intermediate oxidation state. Thus, from this latter resting state, two “fans” of different velocity can be turned on and off by simple chemical redox processes.
GnRH Stimulates Peptidylarginine Deiminase Catalyzed Histone Citrullination in Gonadotrope Cells (2016)

Peptidylarginine deiminase (PAD) enzymes convert histone tail arginine residues to citrulline resulting in chromatin decondensation. Our previous work found that PAD isoforms are expressed in female reproductive tissues in an estrous cycle-dependent fashion, but their role in the anterior pituitary gland is unknown. Thus, we investigated PAD expression and function in gonadotrope cells. The gonadotrope-derived LβT2 cell line strongly expresses PAD2 at the protein level compared with other PAD isoforms. Consistent with this, PAD2 protein expression is highest during the estrous phase of the estrous cycle and colocalizes with the LH β-subunit in the mouse pituitary. Using the GnRH agonist buserelin (GnRHa), studies in LβT2 and mouse primary gonadotrope cells revealed that 30 minutes of stimulation caused distinct puncta of PAD2 to localize in the nucleus. Once in the nucleus, GnRHa stimulated PAD2 citrullinates histone H3 tail arginine residues at sites 2, 8, and 17 within 30 minutes; however, this effect and PAD2 nuclear localization was blunted by incubation of the cells with the pan-PAD inhibitor, biphenyl-benzimidazole-Cl-amidine. Given that PAD2 citrullinates histones in gonadotropes, we next analyzed the functional consequence of PAD2 inhibition on gene expression. Our results show that GnRHa stimulates an increase in LHβ and FSHβ mRNA and that this response is significantly reduced in the presence of the PAD inhibitor biphenyl-benzimidazole-Cl-amidine. Overall, our data suggest that GnRHa stimulates PAD2-catalyzed histone citrullination in gonadotropes to epigenetically regulate gonadotropin gene expression.
Determination of complex formation constants of neptunium(V) with propionate and lactate in 0.5–2.6 m NaCl solutions at 22–60°C using a solvent extraction technique (2019)

Abstract Natural clay rocks like Opalinus (OPA) and Callovo-Oxfordian (COx) clay rock are considered as potential host rocks for deep geological disposal of nuclear waste. However, small organic molecules such as propionate and lactate exist in clay rock pore water and might enhance Np mobility through a complexation process. Therefore, reliable complex formation data are required in the frame of the Safety Case for a nuclear waste repository. A solvent extraction technique was applied for the determination of <m:math xmlns:m="http://www.w3.org/1998/Math/MathML"> <m:mrow> <m:msubsup> <m:mrow> <m:mtext>NpO</m:mtext> </m:mrow> <m:mn>2</m:mn> <m:mo>+</m:mo> </m:msubsup> </m:mrow> </m:math> ${\rm{NpO}}_2^ + $ complexation with propionate and lactate. Extraction was conducted from isoamyl alcohol solution containing 10 −3 M TTA and 5 · 10 −4 M 1,10-phenanthroline. Experiments were performed in 0.5–2.6 m NaCl solutions at temperatures ranging from 22 to 60 °C. Formation of 1:1 Np(V) complexes for propionate and lactate was found under the studied conditions. The SIT approach was applied to calculate equilibrium constants β °(T) at zero ionic strength from the experimental data. Log β °(T) is found linearly correlated to 1/ T for propionate and lactate, evidencing that heat capacity change is near 0. Molal reaction enthalpy and entropy ( <m:math xmlns:m="http://www.w3.org/1998/Math/MathML"> <m:mrow> <m:msub> <m:mi>Δ</m:mi> <m:mtext>r</m:mtext> </m:msub> <m:msubsup> <m:mi>H</m:mi> <m:mtext>m</m:mtext> <m:mo>∘</m:mo> </m:msubsup> </m:mrow> </m:math> ${\Delta _{\rm{r}}}H_{\rm{m}}^ \circ $ and <m:math xmlns:m="http://www.w3.org/1998/Math/MathML"> <m:mrow> <m:msub> <m:mi>Δ</m:mi> <m:mtext>r</m:mtext> </m:msub> <m:msubsup> <m:mi>S</m:mi> <m:mtext>m</m:mtext> <m:mo>∘</m:mo> </m:msubsup> </m:mrow> </m:math> ${\Delta _{\rm{r}}}S_{\rm{m}}^ \circ $ ) could therefore be derived from the integrated van’t Hoff equation. Data for log β ° (298.15 K) are in agreement with literature values for propionate and lactate. Np(V) speciation was calculated for concentrations of acetate, propionate and lactate measured in clay pore waters of COx. In addition, the two site protolysis non-electrostatic surface complexation and cation exchange (2SPNE SC/CE) model was applied to quantitatively describe the influence of Np(V) complexation on its uptake on Na-illite, a relevant clay mineral of OPA and COx.
Propiedades estructurales, magnéticas y dinámicas de clústers de metales de transición en sustratos metálicos (2001)

En esta Memoria se analizan diversas propiedades de clusters soportados de metales de transicion y nobles, tanto sobre sustratos de un mismo metal como sobre otro metal diferente. Elegimos el Al como base para los sistemas mixtos por ser sistemas muy empleados en tecnologias y de los que se dispone abundante informacion experimental. Cada uno de estos estudios se realizo en base a los resultados obtenidos mediante simulaciones por ordenador. Las bases de los modelos empleados aso como de los metodos de simulacion se describen en los capitulos 2 y 3. En el capitulo 4 se calcularon propiedades estaticas de clusters de Ni sobre las superficies Ni(001), Ni(110) y Ni(111), viendo que estas dependen de los parametros experimentales empleados en el ajuste de las funciones del potencial. En el capitulo 5 se extendio este estudio comparativo a las propiedades de fusion de clusters de Ni,Pd,Pt,Cu,Ag y Au soportados sobre una superficie del mismo tipo de metal, viendo que existen notables diferencias entre los metales en cuanto a los mecanismos de difusion superficial previos a la fusion. En el capitulo 6 se realizo un estudio preliminar del sistema Ni-Al/I(001), mostrando la tendencia de los clusters a introducirse en el sustrato, desplazando a los atomos de Al de su posicion de equilibrio. En el capitulo 7 se profundizo en el estudio de este sistema, junto con estudios similares para las superficies Al(110) y Al(111). Nuestros resultados muestran que los clusters introducidos en el sustrato son siempre mas estables que los adsorbidos y que el Ni pierde su momento magnetico por hibridacion de sus estados d con los estados sp del Al. En el capitulo 8 se calcularon propiedades estructuras mas estables tambien estan introducidas en el sustrato. Estos clusters presentan un momento magnetico no nulo al ser depositados sobre esta superficie. Finalmente, en el capitulo 9, se calcularon las estructuras mas estables y modos de crecimiento
Investigating the Effect of Positional Isomerism on the Assembly of Zirconium Phosphonates Based on Tritopic Linkers (2019)

We report on the use of a novel tritopic phosphonic linker, 2,4,6-tris[3-(phosphonomethyl)phenyl]-1,3,5-triazine, for the synthesis of a layered zirconium phosphonate, named UPG-2. Comparison with the structure of the permanently porous UPG-1, based on the related linker 2,4,6-tris[4-(phosphonomethyl)phenyl]-1,3,5-triazine, reveals that positional isomerism disrupts the porous architecture in UPG-2 by preventing the formation of infinitely extended chains connected through Zr-O-P-O-Zr bonds. The presence of free, acidic P-OH groups and an extended network of hydrogen bonds makes UPG-2 a good proton conductor, reaching values as high as 5.7x10&lt;sup&gt;-4&lt;/sup&gt; S cm&lt;sup&gt;-1&lt;/sup&gt;.&lt;br&gt;
Galactomannan Pentasaccharide Produced from Copra Meal Enhances Tight Junction Integration of Epithelial Tissue through Activation of AMPK (2019)

Mannan oligosaccharide (MOS) is well-known as an effective fed supplement for livestock to increase their nutrients absorption and health status. Pentasaccharide of mannan (MOS5) was reported as a molecule that possesses the ability to increase tight junction of epithelial tissue, but the structure and mechanism of action remains undetermined. In this study, the mechanism of action and structure of MOS5 were investigated. T84 cells were cultured and treated with MOS5 compared with vehicle and compound C, a 5'-adenosine monophosphate-activated protein kinase (AMPK) inhibitor. The results demonstrated that the ability of MOS5 to increase tight junction integration was inhibited in the presence of dorsomorphine (compound C). Phosphorylation level of AMPK was elevated in MOS5 treated group as determined by Western blot analysis. Determination of MOS5 structure was performed using enzymatic mapping together with <sup>1</sup>H, <sup>13</sup>C NMR, and 2D-NMR analysis. The results demonstrated that the structure of MOS5 is a β-(1,4)-mannotetraose with α-(1,6)-galactose attached at the second mannose unit from non-reducing end.
Identification of Pseudopolymorphism of Magnesium Stearate by Using Low-Frequency Raman Spectroscopy (2016)

Magnesium stearate (Mg-St), which is currently available on the market, has a wide variety of properties, including pseudopolymorphism, relative content of stearic acid in fatty acid, and particle size. These properties of Mg-St influence manufacturing processes of pharmaceutical products, and therefore, it is necessary to control the quality of Mg-St from suppliers. The purpose of this study was to evaluate the low-frequency region of Raman spectroscopy for identification of pseudopolymorphism in Mg-St. Ten samples of Mg-St obtained from different suppliers were measured by powder X-ray diffraction (PXRD) and thermogravimetry and differential thermal analysis (TG-DTA) to identify the pseudopolymorphism of Mg-St. Then we investigated the relationship between their Raman spectra, including the low-frequency region, and pseudopolymorphism. The results were categorized as four types of Mg-St, namely, mono-, di-, and trihydrate and their mixture. The conventional region of the Raman spectrum (greater than 200 cm–1) was able to identify pseudopolymorphism to a certain degree, but it was not easy to completely distinguish pseudopolymorphism for the mixture of Mg-St. In contrast, the low-frequency region of the Raman spectrum (less than 200 cm–1) was able to clearly distinguish them. These data suggest that Raman spectroscopy, especially in the low-frequency region, is an effective method for rapid identification of pseudopolymorphism in Mg-St.
Data supporting "Stochastic spin flips in polariton condensates: nonlinear tuning from GHz to sub-Hz" (2018)

Data used to create the figures in "Stochastic spin flips in polariton condensates: nonlinear tuning from GHz to sub-Hz". Part of del Valle-Inclan Redondo's thesis "Spin and lattice properties of optically trapped exciton polaritons"
Role of solvent on structure, viscoelasticity, and mechanical compressibility in nanocellulose‐reinforced poly(vinyl alcohol) hydrogels (2018)

ABSTRACT Cellulose nanocrystals (CNCs) reinforced polyvinyl alcohol (PVA)‐based hydrogels with high water content and tunable mechanical properties that can be molded in to any desired shape are presented in this work. Freeze thawing of PVA‐CNC solutions in a mixed solvent system of dimethyl sulfoxide and water enabled to produce a set of physically crosslinked hydrogels with tunable mechanical properties. It was observed that the composition of the solvent altered the mechanical properties and network structure in the hydrogel systems. Differential scanning calorimetry was used to understand the thermal events behind solvent effect on the properties of the hydrogel. Optical microscopy results suggest that these hydrogels possess a macroporous structure. Furthermore, dynamic viscoelastic analysis and axial compression tests have shown that the viscoelastic and mechanical compression properties of the hydrogels improved upon reinforcement with CNC. Overall, the hydrogel enjoys appealing properties as a synthetic biomaterial for soft tissue applications. © 2018 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2019 , 136 , 47044.
Temperature-dependent Gain and Loss in High Performance Quantum Cascade Lasers at 8.2 and 10.3&amp;#x003BC;m (2007)

Temperature-dependent optical gain and waveguide loss were measured for Quantum Cascade lasers with wavelengths of ~8.2 and ~10.3 mum. The nature of the temperature dependence of the loss indicates an extra mechanism of resonant intersubband absorption.
ChemInform Abstract: Palladium‐Catalyzed ortho‐Arylation of Carbamate‐Protected Estrogens. (2016)

Abstract Removal of the carbamate directing group is demonstrated.
Influence of Granulating Method on Physical and Mechanical Properties, Compression Behavior, and Compactibility of Lactose and Microcrystalline Cellulose Granules (2000)

The physical and mechanical properties of lactose (LC) and microcrystalline cellulose (MCC) granules prepared by various granulating methods were determined, and their effects on the compression and strength of the tablets were examined. From the force-displacement curve obtained in a crushing test on a single granule, all LC granules appeared brittle, and MCC granules were somewhat plastically deformable. Inter-granular porosity epsilon inter clearly decreased with greater spherical granule shape for both materials. Decrease in intragranular porosity epsilon intra enhanced the crushing force of a single granule Fg. Agitating granulation brought about the most compactness and hardness of granules. In granule compression tests, the initial slope of Heckel plots K1 appeared closely related to ease of filling voids in a granule bed by the slippage or rolling of granules. The reciprocal of the slope in the succeeding step 1/K2 in compression of MCC granules indicated positive correlation to Fg, while in LC granules, no such obvious relation was evident. 1/K2 differed only slightly among granulating methods. Tensile strength of tablets Tt obtained by compression of various LC granules was low as a whole and was little influenced by granulating method. For MCC granules, which are plastically deformable, tablet strength greatly depended on granulation. Granules prepared by extruding or dry granulation gave strong tablets. Tablets prepared from granules made by the agitating method showed particularly low Tt. From stereomicroscopic observation, the contact area between granule particles in a tablet appeared smaller; this would explain the decrease in inter-granular bond formation.
Collaboratively maintaining semantic consistency of heterogeneous concepts towards a common concept set (2010)

In e-business, creating a common concept set for business integration, interoperation and interaction has to consider the heterogeneity reality of different interpretations from multiple concept providers. Maintaining semantic consistency between multiple concept providers is a difficult problem. To solve this problem, this paper first reviewed the existing technologies of collaborative editing systems and consistency maintenance in the areas of both CSCW and e-business. Based on the discussion of existing technologies, it then proposes a novel CHCES approach, which divides a collaborative editing system into two layers in topology and introduces four strategies to edit common concepts between the two layers. A set of operations is designed, which demonstrates the solution.
Improved tungsten nanofabrication for hard X-ray zone plates (2015)

We present an improved nanofabrication method of high aspect ratio tungsten structures for use in high efficiency nanofocusing hard X-ray zone plates. A ZEP 7000 electron beam resist layer used for patterning is cured by a second, much larger electron dose after development. The curing step improves pattern transfer fidelity into a chromium hard mask by reactive ion etching using Cl2/O2 chemistry. The pattern can then be transferred into an underlying tungsten layer by another reactive ion etching step using SF6/O2. A 630 nm-thick tungsten zone plate with smallest line width of 30 nm was fabricated using this method and characterized. At 8.2 keV photon energy the device showed an efficiency of 2.2% with a focal spot size at the diffraction limit, measured at Diamond Light Source I-13-1 beamline.