gebhart/patrepeval huggingface dataset:
Bacterial biofilm formation on indwelling urethral catheters (2019)

Urethral catheters are the most commonly deployed medical devices and used to manage a wide range of conditions in both hospital and community care settings. The use of long-term catheterization, where the catheter remains in place for a period >28 days remains common, and the care of these patients is often undermined by the acquisition of infections and formation of biofilms on catheter surfaces. Particular problems arise from colonization with urease-producing species such as Proteus mirabilis, which form unusual crystalline biofilms that encrust catheter surfaces and block urine flow. Encrustation and blockage often lead to a range of serious clinical complications and emergency hospital referrals in long-term catheterized patients. Here we review current understanding of bacterial biofilm formation on urethral catheters, with a focus on crystalline biofilm formation by P. mirabilis, as well as approaches that may be used to control biofilm formation on these devices. SIGNIFICANCE AND IMPACT OF THE STUDY: Urinary catheters are the most commonly used medical devices in many healthcare systems, but their use predisposes to infection and provide ideal conditions for bacterial biofilm formation. Patients managed by long-term urethral catheterization are particularly vulnerable to biofilm-related infections, with crystalline biofilm formation by urease producing species frequently leading to catheter blockage and other serious clinical complications. This review considers current knowledge regarding biofilm formation on urethral catheters, and possible strategies for their control.
EDUM (2016)

Behavior in classroom-based courses is hard to measure at large-scale. In this paper, we propose the EDUM (EDUcation Measurement) system to help characterize educational behavior through data collected from WLANs (WiFi networks) on campuses. EDUM characterizes students' punctuality (attendances, late arrivals, and early departures) for lectures using longitudinal WLAN data, and further characterizes the attractiveness of lectures using mobile phone's interactive states at minute-scale granularity. EDUM is easy to deploy and extensible for new types of data. We deploy EDUM at Tsinghua University where ~700 volunteer students' data are measured during a 9-week period by ~2,800 APs and two popular mobile apps. Our results show that EDUM makes it possible to obtain large-scale observations on punctuality, distraction and study performance, and quantitatively confirm or disprove numerous assumptions about educational behavior.
Hemicraniectomy for malignant middle cerebral artery infarction (2009)

Data from the published trials leave no doubt about the benefit especially the life-saving character of hemicraniectomy for malignant hemispheric infarction. However, some open questions (i.e. timing of surgery, age limit for hemicraniectomy) remain to be answered in the future.
Nonlinear acoustic properties of perforated liners: New theory and experiment (2011)

A new nonlinear impedance model of a micro-perforated panel (MPP) is developed using an equivalent fluid concept, which is relatively easy to integrate into the Transfer Matrix Method (TMM) to predict performance of multiple MPP sound absorbers. The nonlinear model is proposed to change the linear-end correction of the acoustic mass in terms of tortuosity. The proposed nonlinear equivalent tortuosity is given by nonlinear end correction. It is found that the effect of the vibration of the air particles on the baffle in the vicinity of the aperture increases the thermo-viscous frictions. As a first validation of the model, an experimental investigation of the linear and nonlinear impedance of single degree of freedom 1 DOF and 2DOF MMP based liners are used with different type of geometric parameter. A good agreement is found between the model and the experiments for the reactance part. This confirms the correction of the radiation part of the present model.
Expression, functional, and structural analysis of proteins critical for otoconia development (2010)

Otoconia, developed during late gestation and perinatal stages, couple mechanic force to the sensory hair cells in the vestibule for motion detection and bodily balance. In the present work, we have investigated whether compensatory deposition of another protein(s) may have taken place to partially alleviate the detrimental effects of Oc90 deletion by analyzing a comprehensive list of plausible candidates, and have found a drastic increase in the deposition of Sparc-like 1 (aka Sc1 or hevin) in Oc90 null versus wt otoconia. We show that such up-regulation is specific to Sc1, and that stable transfection of Oc90 and Sc1 full-length expression constructs in NIH/3T3 cells indeed promotes matrix calcification. Analysis and modeling of Oc90 and Sc1 protein structures show common features that may be critical requirements for the otoconial matrix backbone protein. Such information will serve as the foundation for future regenerative purposes.
Evaluation of the iPad as a low vision aid for&amp;nbsp;improving reading ability (2014)

The iPad, a new portable electronic media device, can be adapted by LVPs to improve their reading ability.
New reactions of 2-alkylthiopenems (1987)

The conversion of 2-alkylthiopenems into the 2-thioxopenam, 2-oxopenam, 2-O-alkylpenem, and into the 2-unsubstituted penem, and the reactivity of 2-alkylthiopenems to various types of chlorinating agents is described.
Systemic Overexpression of the α<sub>1B</sub>‐Adrenergic Receptor in Mice: An Animal Model of Epilepsy (2002)

The selective overexpression of the alpha 1B-AR is associated with increased in vivo spontaneous interictal epileptogenicity and EEG/behavioral seizures. These results suggest a possible role (direct or indirect) for the alpha 1B-ARs in the development and expression of epileptogenicity.
A DNA polymorphism with KpnI of the human liver-type phosphofructokinase (PFKL) gene (1988)

DESCRIPTION OF CLONE: The 3.3 kb genomic BamHI fragment of human liver phosphofructokinase (PFKL) gene cloned in the BamHI site of pGEM-3 to produce clone pG-PFKL 3.3 was used as a hybridization probe. POLYMORPHISM: After digestion with KpnI and Southern blotting, the PFKL probe hybridizes to a 1.7 kb DNA fragment (allele Al) when the polymorphic KpnI site is present and a 1.9 kb fragment (allele A2) when the site is absent (see Figure ).
Pierre Robin Syndrome Combined with Unilateral Choanal Atresia (1987)

A case of Pierre Robin syndrome (mandibular hypoplasia, cleft palate, and glossoptosis), associated with a unilateral choanal atresia in a full-term infant, is described. The pathogenesis of this combined anomaly is discussed through review of the embryologic development of the craniofacial structures. Diagnostic and management alternatives are reviewed.
Abstract 1 (2012)

AMERICAN SOCIETY OF PLASTIC SURGEONS PLASTIC & RECONSTRUCTIVE SURGERY PRS GLOBAL OPEN ASPS EDUCATION NETWORK AMERICAN SOCIETY OF PLASTIC SURGEONS PLASTIC & RECONSTRUCTIVE SURGERY PRS GLOBAL OPEN ASPS EDUCATION NETWORK
Carcinoma Right Breast (post-operative Chemotherapy and Radiotherapy) with bone and lung metastases: A Case Report and Review of Literature (2016)

It is generally observed that triple negative breast cancer patients do not get benefited from endocrine targeted therapies. However, by a thorough Systematic review and critical analysis of the literature it could be depicted that a subset with Androgen Receptor expression could respond to anti-androgen therapies up to some extent. Presented here is a 65-years-old Postmenopausal female with a 5-year history of Carcinoma Right Breast (postoperative Chemotherapy and Radiotherapy) with bone and lung metastases, advanced, Grade III tumor diagnosed as Metastatic Adenocarcinoma on histology. This case had been presented to identify the role of Androgen Receptors in inhibiting and suppressing the tumor growth in breast oncology and to conclude that traditional Anti-Androgen therapy, that is, Bicalutamide could be considered as a differential diagnosis of Triple negative breast cancer metastatic tumors. Therefore, the present article represents some deeper insights regarding Androgen, Androgen-Receptor, Anti-Androgen drug-Bicalutamide and their role of action in the post-menopausal Triple Negative Breast cancer women with positive expression of Androgen Receptor.
Collaboration support for novice team programming (2005)

Learning computer programming in a modern university course is rarely an individual activity; however, IDEs used in introductory programming classes do not support collaboration at a level appropriate for novices. The goal of our research is to make it easier for first-year students to experience working in a team in their programming assignments. Based on our previous work developing and evaluating IDEs for novice programmers, we have identified two main areas of required functionality: 1) features for code sharing and coordination; and 2) features to support communication. We have extended an existing teaching-oriented integrated development environment (called Gild) with features to support code sharing and coordination. We report on a preliminary study in which pairs of students used a prototype of our collaborative IDE to work on a programming assignment. The goals of this study were to evaluate the effectiveness and usability of the new features and to determine requirements for future communication support.
A Divergent Testis-Specific α-Tubulin Isotype that does not Contain a Coded C-Terminal Tyrosine (1987)

On the basis of analysis of cDNA clones of alpha-tubulin RNAs expressed during spermiogenesis in chickens, we report the identification of a novel alpha-tubulin which is expressed exclusively in chicken testes. Comparison of its sequence with those previously determined not only demonstrates that the encoded polypeptide is significantly divergent from other alpha-tubulins but also supports the hypothesis that alpha-tubulin isotypes are distinguished by a carboxy-terminal variable region sequence and, to a lesser extent, by a domain near the amino terminus. Since essentially all previously known alpha-tubulins undergo a unique cycle of removal and posttranslational readdition of a tyrosine residue at the extreme carboxy terminus, the presence in this testes alpha-tubulin of a very divergent carboxy terminus that does not contain an encoded tyrosine raises the possibility that this polypeptide does not participate in the usual cycle of tyrosination/detyrosination.
Two unique approaches for actively controlling the interior acoustic response of a cylindrical aircraft enclosure using active constrained layer damping and end actuation (1999)

Experimental results are reported involving the use of 12 active constrained layer damping (ACLD) patches instrumented on a fuselage section under radial point excitation. ACLD utilizes an active piezo film constraining layer over a viscoelastic layer to increase damping and apply restoring moments. Results reported to date showed that performance was achieved both in the reduction of the interior acoustic response and of the structural vibratory response. A more detailed analysis is reported here of the uncontrolled/controlled structural acoustics derived from high spatially sampled surface velocity and interior pressure measurements. A second control approach is reported where interior acoustic levels are reduced by control of the efficient end cap coupling to the interior by placing control actuators on each end. Analytic and numeric models are used to identify three dominate interior acoustic mechanisms: (1) a forced response on the interior by purely structural modes, (2) purely normal acoustic cavity modes, and (3) mixed structural/acoustic modes. Numeric control ‘‘experiments’’ are reported where both interior acoustic minimization and end-constraint control laws are employed. Good performance was found and discussion will involve the effectiveness of the control laws on each of these mechanisms. [Work supported in part by NASA, Langley.] a)Also SFA, Inc.
Measurement of Electrostatic Latent Image on Photoconductors by Use of Electron Beam Probe (2009)

A novel method that makes possible the measurement of an electrostatic latent image on a photoconductor is proposed. An electrostatic latent image is formed by electron charging and by laser exposing of a photoconductor within a vacuum chamber. The electrostatic latent image is measured by detecting secondary electrons generated by the scanning of an electron beam probe. When a primary electron beam hits the photoconductor, secondary electrons are generated. Secondary electrons generated in a charged area travel to an electron detector. In contrast, secondary electrons generated in an exposed area are pulled back to the photoconductor, thereby decreasing the number of secondary electrons that reach the detector. The exposed and charged areas are determined in this way. The significant feature of this method is that the means of charging, exposing, and detecting are all incorporated in the same system, making real-time measurement possible. This method has good performance with high-resolution measurement on the order of microns.
Transitional Techniques in the Bible (1983)

Research Article| December 01 1983 Transitional Techniques in the Bible H. Van Dyke Parunak H. Van Dyke Parunak Search for other works by this author on: This Site Google Journal of Biblical Literature (1983) 102 (4): 525–548. https://doi.org/10.2307/3260864 Cite Icon Cite Share Icon Share Facebook Twitter LinkedIn MailTo Permissions Search Site Citation H. Van Dyke Parunak; Transitional Techniques in the Bible. Journal of Biblical Literature 1 December 1983; 102 (4): 525–548. doi: https://doi.org/10.2307/3260864 Download citation file: Zotero Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All Scholarly Publishing CollectiveSBL PressJournal of Biblical Literature Search Advanced Search The text of this article is only available as a PDF. Article PDF first page preview Close Modal You do not currently have access to this content.
Risks of Colorectal and Other Cancers After Endometrial Cancer for Women With Lynch Syndrome (2013)

Women with Lynch syndrome who are diagnosed with endometrial cancer have increased risks of several cancers, including breast cancer.
Urban Built Environment Analysis: Evidence from a Mobility Survey in Madrid (2014)

Applications involving travel behavior from the perspective of land use are dating from the 1990s. Usually, four important components are distinguished: density, diversity and design (3D's of Cervero and Kockelman) and accessibility (introduced by Geurs and van Wee). But there is not a general agreement on how to measure each of those 4 components. Density is used to be measured as population and employment densities, but others authors separate population density between residential and building densities. A lot of measures have been developed to estimate diversity: among others, a dissimilarity index to indicate the degree to which different land uses lie within one another's surrounding, an entropy index to quantify the degree of balance across various land use types or proximities to commercial-retail uses. Design has been characterized by site design, and dwelling and street characteristics. Lastly, accessibility has become a frequently used concept, but its meaning on travel behavior fi eld always refers to the ability “to reach activities or locations by means of a travel mode”, measured as accessibility to jobs, to leisure activities, and others. Furthermore, the previous evidence is mainly based on US data or on north European countries. Therefore, this paper adds some new evidence from a Spanish perspective to the research debate. Through a Madrid smartphone-based survey, factor analysis is used to linearly combine variables into the 3D's and accessibility dimensions of the built environment. At a first step for future investigations, land use variables will be treated to define accurately the previous 4 components.
1-D and 2-D Modeling of Power and Energy Transduction of Piezoelectric Wafer Active Sensors for Structural Health Monitoring (2011)

This paper presents an investigation of power and energy transduction in piezoelectric wafer active sensors (PWAS) on isotropic structure for structural health monitoring (SHM). After a literature review of the state of the art, we developed a power and energy model for PWAS on an isotropic beam. We performed 1-D and 2-D model of the power and energy transduction for PWAS transducers attached to structure. This 1-D and 2-D model allows examination of power and energy flow for linear and circular crested wave pattern. The power and energy transduction flow chart for a complete pitch-catch setup is examined. At each stage, the electro-acoustic power and energy transduction of the PWAS transmitter and receiver are examined. The power flow converts from electrical source into piezoelectric power at the transmitter, the piezoelectric transduction converts the electrical power into the mechanical interface power at the transmitter PWAS and then into acoustic wave power travelling in the structure. The wave power arrives at the receiver PWAS and is captured at the mechanical interface between the receiver PWAS at the structure. The mechanical power captured is converted back into electrical power in the receiver PWAS and captured at the receivers electric instrument. The parametric study of PWAS size, impedance match gives the PWAS design guideline for PWAS sensing and power harvesting applications.
Helping patients make informed decisions. Two-year evaluation of the Gustave Roussy prostate cancer multidisciplinary clinic (2018)

The experience of a multidisciplinary consultation in the initial management of non-metastatic prostate cancer renders high patient satisfaction, improves their appreciation of feeling better informed, promotes active participation and shared decision-making and strongly influences their final decision.
The continuous casting behavior of medium manganese steels (2021)

The continuous casting behavior of medium manganese steels (MMnS: 6Mn, 6Mn–1Si, 6Mn–1Si–1Al, 10Mn–1Si and 10Mn–1Si–1Al) have been investigated and compared with unalloyed carbon steel C30. A series of in-situ melting/re-solidification hot tensile tests were conducted in the temperature range 800–1450 °C. The corresponding tensile forces and ductility parameters were monitored. Differential thermal analysis (DTA) was applied to determine the liquidus temperatures. The solidified zones and fracture surfaces of the tested specimens were analyzed using scanning electron microscopy (SEM). Scheil-solidification and equilibrium thermodynamic calculations were performed to explore the solidification and precipitation behavior. The processability of MMnS using thin slab casting technology has been discussed in light of their hot ductility behavior. The findings indicate the prime role of precipitation, phase transformation and extension/shift of solidification intervals induced by the alloying concepts in controlling the hot ductility of MMnS. It turns out that the formation of MnS, complex AlN and MnS precipitates and δ-ferritic solidification deteriorates the high temperature ductility. A shift of the second hot ductility drop to higher temperatures was identified for the Al-containing and high-Mn content MMnS when compared to the reference steel C30. This study demonstrates the adequate hot ductility (>30%) of MMnS 6Mn and 6Mn–1Si as well as reference steel C30 for thin slab casting technology, while higher Al-containing MMnS undergo a ductility drop in the straightening temperature range (900–1080 °C), which impairs their castability. An optimization of their alloying concepts, especially Al-content, is recommended to tune their continuous casting behavior.
Cell Spectral Efficiency Analysis of Relay Enhanced and Picocell Enhanced LTE Systems (2014)

A novel analytical framework is presented to evaluate resource consumption, error ratio, and spectral efficiency on PHY, MAC and RLC layer in relay enhanced 3GPP LTE systems. Thereby, various aspects of the various LTE protocol layers are modeled: On PHY layer, association of user terminal to a radio access point, probabilistic radio channel states, adaptive modulation and coding, overhead in LTE radio frame, turbo coded M-QAM block error rate, and Chase combining are taken into account. On MAC layer, hybrid-ARQ protocol, resource assignment failure, and feedback misdetection are accounted for. On RLC layer, segmentation of a RLC SDU into several RLC PDUs, selective repeat - ARQ protocol, feedback loss, and timer for upcoming feedback to be waited for are considered. Aspect of two hop transmission is modeled and analyzed for decode and forward relaying. The framework is useful to evaluate various performance parameters for relay enhanced cells and for picocell enhanced donor cells as well: Resource consumption, error ratio and spectral efficiency are calculated as CDFs for any location in a multi-cell scenario, as location specific expected values, as CDFs for a cell, and as related expected values and percentiles.
Antagonism of responses to excitatory amino acids on rat cortical neurones by the spider toxin, argiotoxin<sub>636</sub> (1989)

1. Several low molecular weight spider toxins have recently been shown to block potently glutamatergic neuromuscular transmission at the invertebrate neuromuscular junction. The aim of the present investigation was to evaluate the effects of one such toxin, argiotoxin636, on excitatory amino acid receptor-mediated responses in mammalian neurones. 2. Membrane currents were recorded from rat cortical neurones after 2-6 weeks in cell culture, by the whole-cell variant of the patch-clamp technique. N-methyl-D-aspartate (NMDA) and kainate were used as selective agonists for their respective receptor subtypes. alpha-Amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid (AMPA) was used as a selective agonist for the quisqualate receptor subtype. 3. Responses to these agonists were characterised with respect to their concentration and voltage-dependence. Argiotoxin636 (3-30 microM) was found to attenuate markedly responses to NMDA in an agonist- and voltage-dependent manner. Thus, argiotoxin636 progressively reduced successive responses to NMDA when membrane potentials were voltage clamped between -40mV to -100 mV. The more negative the membrane potential the more rapid the development of the block of inward current. 4. The antagonism of NMDA-induced currents by argiotoxin636 could be reversed by clamping the membrane at positive potentials (+20 to +60 mV) and reapplying NMDA. 5. Responses to AMPA and kainate were less affected by argiotoxin636, with an antagonist action only becoming evident at a concentration of 100 microM. 6. These results suggest that argiotoxin636 is an open-channel blocker of the NMDA activated ion-channel in mammalian neurones. Furthermore, our results indicate at least a 30 fold selectivity for NMDA over the quisqualate- and kainate-activated ion-channels.
[Deep lamellar keratoplasty in severe ocular surface disease]. (2007)

DLKP is an effective means to treat stromal opacity in patients with ocular surface disease.