gebhart/patrepeval huggingface dataset:
5 Volt Plateau in LiMn2 O 4 Thin Films (1995)

A plateau with a median voltage of ∼5 V, possibly due to Li+ ions occupying octahedral sites in the spinel structure, has been observed on charging crystalline spinel thin‐film cathodes to 5.3 V. The total charge extracted from the 4 and 5 V plateaus corresponds to, but the distribution of capacity between the two plateaus varies from film to film. After charging to 5.3 V, the cathodes were irreversibly changed: the capacity of the 4 V plateau increased by as much as 50%, but the cell resistance also increased significantly due to degradation of the cathode.
Long term efficacy of hepatitis B vaccine in infants born to hepatitis B e antigen-positive mothers (1992)

The long term protective efficacy of recombinant hepatitis B vaccine, administered alone or concomitantly with hepatitis B immunoglobulin, was assessed in 263 healthy neonates of hepatitis B e antigen-positive mothers. Infants received the first dose of vaccine at birth; additional doses were given at either Months 1, 2 and 12 or Months 1 and 6. During the follow-up period, which ranged from 2 to 4 years, protective titers (&ge;10 mIU/ml) of anti-hepatitis B surface antibodies were found in virtually all infants who had responded to the primary course of vaccination. “Natural boosts,” without persistent infection, were observed in only a small number of children. All children who were shown to have become chronic carriers were infected within the first year of life. No statistical difference in long term protective efficacy could be shown between the two vaccination schedules used or between the use of vaccine alone or vaccine plus hepatitis B immunoglobulin for either schedule.
Mobile transactional agents (2002)

Mobile agents is an important enabling technology for certain types of real world applications such as e-commerce and workflows. While the potential benefits are appealing, this technology is not being used by many applications. This is largely attributed to the lack of components such as transactions and their integration with de-facto technologies. This work focuses on bridging this gap and devising an extended transactional model for mobile agents. The nature of mobile agents for autonomous processing and mobility introduces numerous challenges with respect to transactions which are originally, addressed in our work. First, given that, unstructured, execution scripts for agents, it is necessary to isolate side-effects that occur between two successive migrations to later be able to commit or abort them locally according to transaction semantics maintained across multiple hosts. Second, intra-transaction parallelism requires synchronization among multiple autonomous agents to join their processing and to rollback a transaction. Third, recovery from failures at a specific host, may necessitate maintaining a global state of a transaction across all the agent's destinations to determine how to proceed (e.g., repeat activities upon recovery). This paper presents a comprehensive transaction model for mobile agents and its deployment in the context of Java-based mobile agents. The overall complexity of transaction management is handled using a division of labor between an object-oriented programming model, protocols and a concurrency control mechanism. Specifically, the programming model maintains separation of concerns between mobility, transactions and application logic in order to cope with the aforementioned challenges.
MyPath (2018)

Following a cancer diagnosis, patients must cope with numerous physical, emotional, and practical challenges. While health information exists to help patients learn how to manage these challenges, health information seeking often declines over time, recalling information is difficult, and limited time with healthcare providers can leave patients feeling uninformed about their illness. We designed MyPath to overcome these information access challenges. The mobile system offers personalized, dynamic, and trusted health information recommendations to help patients learn about and manage their cancer. Through a seven-month deployment study with breast cancer patients, we found that use of the application encouraged proactive health management behaviors, and identified factors that motivated technology adoption and abandonment. We discuss the implications of these results for facilitating use of mHealth tools by a rural patient population and the importance of scaling support to a large range of information needs. We use this work to demonstrate the value of personalized health information systems and to motivate future CSCW research developing personalized support systems for other health situations with complex information access models.
Calcineurin inhibitors in bronchiolitis obliterans syndrome following stem cell transplantation (2013)

Bronchiolitis obliterans is a complication after allogeneic haematopoietic stem cell transplantation (HSCT). Management of bronchiolitis obliterans comprises intensive immunosuppression, but treatment response is poor. We investigated the effect of cyclosporine A (CsA), tacrolimus (FK506), methylprednisolone (mPRED), mycophenolate mofetil (MMF) and everolimus on the proliferation of primary lung myofibroblasts from HSCT patients with bronchiolitis obliterans syndrome (BOS). Cells were isolated from surgical lung biopsies of eight HSCT patients with BOS. Proliferation was assessed by [(3)H]-thymidine incorporation. Biopsies revealed constrictive bronchiolitis obliterans in three patients and lymphocytic bronchiolitis in five patients. CsA and FK506 significantly induced proliferation of myofibroblasts. mPRED and MMF caused a significant inhibition of proliferation, whereas everolimus had no effect. Costimulation with FK506, mPRED and MMF significantly inhibited proliferation. Serial pulmonary function tests over 12 months after lung biopsy and under triple therapy demonstrated that patients with lymphocytic bronchiolitis had a significant improvement in forced expiratory volume in 1 s (FEV1), whereas FEV1 of patients with bronchiolitis obliterans was unchanged. Our data demonstrate a pro-proliferative effect of calcineurin inhibitors on primary human lung myofibroblasts obtained from patients with BOS after HSCT. In contrast, based on the observed antiproliferative capacity of MMF in vitro, MMF-based calcineurin inhibitor-free treatment strategies should be further evaluated in patients with bronchiolitis obliterans after HSCT.
The ARPA-E MOSAIC Program: Advancing Micro-scale Concentrated Photovoltaics (2017)

The MOSAIC program aims to exploit novel micro-optical concentrating techniques to achieve the efficiency of CPV within a low-profile panel. The technical approaches and challenges for the various projects in the program are reviewed.
Table S3 from Ponatinib Shows Potent Antitumor Activity in Small Cell Carcinoma of the Ovary Hypercalcemic Type (SCCOHT) through Multikinase Inhibition (2023)

&lt;p&gt;IC50 summary of validated drug hits in SCCOHT cell lines.&lt;/p&gt;
Apprendre la programmation orientée objet avec le langage Java : avec exercices pratiques et corrigés (2018)

Apres un historique de la POO et du langage Java, l'auteur explique pourquoi ce type de programmation est devenu incontournable pour developper dans les environnements graphiques evenementiels. Les notions d'objet, de classe et de reference sont presentees puis les fondements de la POO que sont l'encapsulation, l'heritage, le polymorphisme et l'abstraction. Les differentes etapes d'un developpement objet avec les principes de modelisation UML sont exposees. L'auteur presente ensuite la machine virtuelle Java, son interet, sa richesse et un environnement de developpement avec IntelliJ IDEA de la societe JetBrains. Le lecteur decouvre comment Java reproduit les principes de la POO en suivant des explications simples, des exemples concrets et en realisant des exercices d'entrainement. Il decouvre egalement les types de base du developpement Java et leur utilisation, comment exploiter un IDE pour simplifier la saisie des programmes et les mettre au point. Les programmes d'essais sont de type console ou graphique, bases sur l'utilisation de Swing pour illustrer les communications entre objets. Quand ils sont pertinents, des paralleles sont menes avec les langages de programmation C++ et C#. La programmation multithread permettant l'execution simultanee de plusieurs flux d'instructions est presentee, suivie d'une introduction aux tests unitaires tellement importants pour fiabiliser les objets. Enfin, le dernier chapitre est consacre a la reflexion en Java qui promet quelques surprises. A la fin de ce livre, le lecteur disposera de bases solides pour apprehender les puissantes API Java et realiser des programmes objet modulaires, fiables et extensibles. [Source : 4e de couv.]
Suppression of ipsilateral motor cortex facilitates motor skill learning (2009)

The primary motor cortex (M1) plays a critical role in early aspects of motor skill learning. Given the notion of inter-hemispheric competition, unilateral disruption of M1 may increase excitability of the unaffected motor cortex and thus improve motor learning with the ipsilateral hand. We applied slow-frequency repetitive transcranial magnetic stimulation (rTMS) before the initiation of practice of a simple motor skill. Participants were randomly divided into three stimulation groups: (i) ipsilateral M1; (ii) contralateral M1; and (iii) Cz (control site). The mean execution time and error rate were recorded in four sessions distributed over 2 days. Disruption of M1 with rTMS slowed down skill acquisition with the contralateral hand, albeit non significantly, but paradoxically enhanced learning with the ipsilateral hand. This was evidenced by a significant decrease of execution time at the end of day 1 in the group that received rTMS over the ipsilateral M1 compared with both control groups (Cz and contralateral M1 stimulation). This supports the notion of inter-hemispheric competition and provides novel insights that may be applicable to neurorehabilitation.
Managing Noise and Interference Separately - Multiple Access Channel Decoding using Soft GRAND (2021)

Two main problems arise in the Multiple Access Channel (MAC): interference from different users, and additive noise channel noise. Maximum A-Posteriori (MAP) joint decoding or successive interference cancellation are known to be capacity-achieving for the MAC when paired with appropriate codes. We extend the recently proposed Soft Guessing Random Additive Noise Decoder (SGRAND) to guess, using soft information, the effect of noise on the sum of users' transmitted codewords. Next, we manage interference by applying ZigZag decoding over the resulting putative noiseless MAC to obtain candidate codewords. Guessing continues until the candidate codewords thus obtained pertain to the corresponding users' codebooks. This MAC SGRAND decoder is a MAP decoder that requires no coordination between users, who can use arbitrary moderate redundancy short length codes of different types and rates.
Constructivism in the Collaboratory (1995)

In our research, we start with a constructivist belief in the importance of an active learner interacting with a variety of resources, developing his or her own understanding through a mixture of experimentation, experience and expert guidance. However, we supplement this constructivist outlook with a sociocultural commitment to the impportance of communication and collaboration with other learners throughout the knowledge construction process. In this paper, we describe a learning environment that we have developed that combines constructivist-inspired tools for open-ended investigation with communication and collaboration tools that support both expert guidance and multi-learner collaboration.
CSRNet: Cascaded Selective Resolution Network for Real-time Semantic Segmentation (2021)

Real-time semantic segmentation has received considerable attention due to growing demands in many practical applications, such as autonomous vehicles, robotics, etc. Existing real-time segmentation approaches often utilize feature fusion to improve segmentation accuracy. However, they fail to fully consider the feature information at different resolutions and the receptive fields of the networks are relatively limited, thereby compromising the performance. To tackle this problem, we propose a light Cascaded Selective Resolution Network (CSRNet) to improve the performance of real-time segmentation through multiple context information embedding and enhanced feature aggregation. The proposed network builds a three-stage segmentation system, which integrates feature information from low resolution to high resolution and achieves feature refinement progressively. CSRNet contains two critical modules: the Shorted Pyramid Fusion Module (SPFM) and the Selective Resolution Module (SRM). The SPFM is a computationally efficient module to incorporate the global context information and significantly enlarge the receptive field at each stage. The SRM is designed to fuse multi-resolution feature maps with various receptive fields, which assigns soft channel attentions across the feature maps and helps to remedy the problem caused by multi-scale objects. Comprehensive experiments on two well-known datasets demonstrate that the proposed CSRNet effectively improves the performance for real-time segmentation.
ChemInform Abstract: Application of a Ritter‐Type Reaction to the Synthesis of Chiral Indane‐Derived C2‐Symmetric Bis(oxazolines). (1996)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Implementation of Selected Data/Knowledge-Base Algorithms on a Digital Optoelectronic Processor. (1996)

Increasing evidence suggests that tumor necrosis factor receptor-associated factor 4 (TRAF4) is an oncogene which is frequently overexpressed in many human carcinomas. Although TRAF4 was originally identified in breast cancer, the underlying mechanism of TRAF4 in tumorigenesis remains largely unknown. In the present study, we found that TRAF4 was overexpressed in cancer cells, and RNA interference (RNAi)-mediated gene knockdown of TRAF4 decreased cell growth, cell migration and invasion. Next, we found that TRAF4 promoted cell survival kinase Akt membrane recruitment, which is essential for Akt activation. Furthermore, we demonstrated a direct interaction between Akt and TRAF4. Additionally, overexpression of constitutively activated Akt reversed cell growth arrest in TRAF4 gene-silenced cells. Taken together, our data indicate that TRAF4 plays an important role in tumorigenesis of breast cancer through direct interaction and activation of Akt, implying that TRAF4 may be a potential molecular target for breast cancer prevention and therapy.
Integrated control and circuit design; an optimization approach applied to the buck converter (2010)

The paper deals with design of power converters for optimal disturbance rejection. Both circuit parameters and control input are optimized simultaneously in a joint procedure. In general, the optimization problem requires solving bilinear matrix inequalities. For the buck converter, we show that the original problem can be reformulated equivalently as two simpler min-max problems that are solved successively. As a result, the optimal circuit parameters which minimize the impact of the disturbance are found. The circuit parameters and control are verified in simulation.
A coprocessor architecture implementing the MPEG-4 visual core profile for mobile multimedia applications (2002)

This paper describes a new VLSI coprocessor architecture implementing the MPEG-4 visual core profile for advanced mobile multimedia terminals and applications. An analysis of the algorithmic requirements and of the constraints in the mobile multimedia applications field leads to an architectural approach based on a RISC core processor and programmable yet specialized coprocessors. We focus on one coprocessor called MacroBlockEngine which supports the tools for the texture processing part in the coding algorithm. The architecture of the MacroBlockEngine is presented in detail and experimental results from the simulations and from the hardware synthesis are given.
Synthesis of PEGylated gold nanorods (Au NRs) as absorption nanoprobes for near-infrared optical imaging (2013)

In this contribution, we show that Au NRs functionalized with PEG molecules can be used as absorption nanoprobes for near-infrared imaging in live animals. We have found that the contrast signal of the in vivo image is dependent upon the transmission ability of the NIR light interacting with the different aspect ratios of Au NRs. Our study was focused on absorption in vivo imaging at 700 nm, which is within the transmission window of the skin. NIR absorption in vivo imaging was carried out by subcutaneous injection of mice with PEGylated Au NRs that have a LSPR around 700 nm. The formulation showed strong contrast signals under the tissues upon irradiation with NIR light. More importantly, our theoretical calculation suggested that the high contrast signals from the PEGylated Au NRs were generated via the NIR light absorption of the Au NRs within the tissue.
Frequency-tunable micromechanical oscillator (2000)

An experimental method, employing a scanning tunneling microscope (STM) as an actuator and a scanning electron microscope (SEM) as a motion detector, was developed to study microelectromechanical systems (MEMS) and has been applied to study microfabricated cantilever beams. Vibrations actuated by an ac voltage applied to the piezodrive are transferred to the sample by the STM tip, which also provides a constraint at the drive location, altering the fundamental mode of the oscillation. A continuous change in the resonant frequency of the cantilever is achieved by varying the position of the STM tip. In contrast to the few percent tunability previously demonstrated for MEMS oscillators, we have varied the cantilever frequency over a 300% range.
A maternal factor conferring resistance to crown rust in <i>Lolium multiflorum</i> cv.‘Axis’ (2000)

Abstract The genetic basis for crown rust resistance was analysed in the progeny of reciprocal crosses between Lolium multiflorum plants that were either resistant (cv. ‘Axis’) or susceptible to crown rust. The progeny harvested from the resistant parent was two‐ to seven‐fold more resistant than the progeny harvested from the susceptible parent. These data indicate the presence of a maternal factor which increases resistance to crown rust in some of the ryegrass plants used as parents.
Acute inflammasome activation and downregulation after severe burn injury in humans. (169.23) (2012)

Abstract Cytokine activation and the systemic pro-inflammatory shock response following burn injury results in multiple organ failure. We hypothesized that the NLRP3 inflammasome (a multiprotein complex constructed in macrophages following stimulation by danger signals), and related genes are elevated following burn injury in humans. We enrolled 18 patients: 7 with large burns (&amp;gt;30% total body surface area burn, TBSA) and 11 with small burns (&amp;lt; 30% TBSA). Blood was collected at 24, 24-48 and 48-72 hours after burn. Mononuclear cells were harvested, total RNA isolated and levels of NRLP3, Caspase-1, IL-1β, Pyrin and TNFα measured using quantitative real time PCR (qtPCR) and compared to normal pooled mRNA. Serum protein levels of Caspase-1, TNFα and IL-1β were quantified by ELISA and compared to normal serum. At all time points and %TBSA, the relative copy number of Caspase-1 mRNA was significantly elevated but IL-1β mRNA was decreased compared to normal. NLRP3, Pyrin and TNFα mRNA copy numbers were unchanged. Protein levels of active IL-1β, TNFα and caspase-1 were significantly increased at all time points and %TBSA. These data indicate that inflammasome component caspase-1 expression is elevated after burn, cleaving pro-IL1β into the active form. Concurrent downregulation of IL-1β gene expression occurs to counter an overt inflammatory response. This is the first transcriptional evidence of inflammasome activation and homeostatic downregulation in burn patients.
Tensile Strength of Joints Bonded With a Nano-particle-Reinforced Adhesive (2008)

Abstract In order to improve the tensile lap shear strength of adhesively bonded joints, nano-particles were dispersed in the adhesive using a 3-roll mill. The dispersion states of nano-particles in the epoxy adhesive were observed with TEM (Transmission Electron Microscopy) with respect to the mixing conditions, and the effect of nano-particles on the mechanical properties of the adhesive was measured with respect to dispersion state and weight content of nano-particles. Also the static tensile load capability of the adhesively bonded double lap joints composed of uni-directional glass/epoxy composite and nano-particle-reinforced epoxy adhesive was investigated to assess the effect of nano-particles on the lap shear strength of the joint. From the experimental and FE analysis results, it was found that the nano-particles in the adhesive improved the mechanical properties of the adhesive. Also the increased failure strain and the reduced CTE (coefficient of thermal expansion) of the nano-particle-reinforced adhesive improved the lap shear strength of adhesively bonded joints. Keywords: DOUBLE LAP JOINTCARBON BLACKNANO-PARTICLESPARTICLE-REINFORCED ADHESIVE
Pt accelerated coarsening of A15 precipitates in Cr-Si alloys (2022)

The effect of alloying Cr-rich Cr-Si alloys with Pt was investigated by a combination of complementary experimental methods and atomic scale modelling. The investigated Cr-Si and Cr-Si-Pt (Cr ⩾86 at.%) alloys developed a two-phase microstructure consisting of Cr solid solution (Crss) matrix and strengthened by A15 precipitates during annealing at 1200°C. It was found that additions of 2 at.% Pt increase the coarsening rate by almost five times considering annealing times up to 522 h. Pt was found to change the precipitate matrix orientation relationship, despite its low influence on the Crss matrix/A15 precipitate misfit. Through this experimental and modelling approach new insight has been gained into mechanisms of enhanced coarsening by Pt addition. The increased coarsening is principally attributed to a change in interface composition and structure resulting in different thermodynamic stabilities: Pt-containing A15 phase was found to have a broader compositional range if both elements, Pt and Si, are present compared to only Si. Additionally, the Crss phase was found to have a higher solubility of Pt and Si over just Si. Both factors additionally facilitated Ostwald ripening.