gebhart/patrepeval huggingface dataset:
Real-time flight data validation for rocket engines (1996)

Real-time validation of rocket engine sensor data improves mission safety and reduces flight operations and ground test costs. NASA Lewis Research Center, in partnership with Expert Microsystems, has developed an innovative sensor validation system enabling real-time, automated sensor failure detection for all types of mission critical systems. Work to date has verified that these sensor validation algorithms enable highly reliable data validation for critical Space Shuttle Main Engine performance sensors, including the turbine discharge temperatures on both turbopumps. We have completed production of a prototype run-time module which has been shown to validate 22 SSME flight sensors in real-time with very high reliability. The Sensor Validation System consists of a sensor validation network development system and a realtime kernel. The network development system provides the workstation-based tools that define the analytical redundancy relations and decision strategy used by the real-time kernel to detect sensor failures in a real-time data stream. The network development system includes an autocode generator which automatically produces the validation files used by the real-time kernel. The real-time kernel plus the autocode generated files form a run-time module which can be easily integrated with the host process. This design enables non-programmers to produce and maintain sensor validation run-time modules for any process application.
Ferrous iron‐ and ammonium‐rich diffuse vents support habitat‐specific communities in a shallow hydrothermal field off the Basiluzzo Islet (Aeolian Volcanic Archipelago). (2017)

Ammonium- and Fe(II)-rich fluid flows, known from deep-sea hydrothermal systems, have been extensively studied in the last decades and are considered as sites with high microbial diversity and activity. Their shallow-submarine counterparts, despite their easier accessibility, have so far been under-investigated, and as a consequence, much less is known about microbial communities inhabiting these ecosystems. A field of shallow expulsion of hydrothermal fluids has been discovered at depths of 170-400 meters off the base of the Basiluzzo Islet (Aeolian Volcanic Archipelago, Southern Tyrrhenian Sea). This area consists predominantly of both actively diffusing and inactive 1-3 meters-high structures in the form of vertical pinnacles, steeples and mounds covered by a thick orange to brown crust deposits hosting rich benthic fauna. Integrated morphological, mineralogical, and geochemical analyses revealed that, above all, these crusts are formed by ferrihydrite-type Fe<sup>3+</sup> oxyhydroxides. Two cruises in 2013 allowed us to monitor and sampled this novel ecosystem, certainly interesting in terms of shallow-water iron-rich site. The main objective of this work was to characterize the composition of extant communities of iron microbial mats in relation to the environmental setting and the observed patterns of macrofaunal colonization. We demonstrated that iron-rich deposits contain complex and stratified microbial communities with a high proportion of prokaryotes akin to ammonium- and iron-oxidizing chemoautotrophs, belonging to Thaumarchaeota, Nitrospira, and Zetaproteobacteria. Colonizers of iron-rich mounds, while composed of the common macrobenthic grazers, predators, filter-feeders, and tube-dwellers with no representatives of vent endemic fauna, differed from the surrounding populations. Thus, it is very likely that reduced electron donors (Fe<sup>2+</sup> and NH<sub>4</sub><sup>+</sup> ) are important energy sources in supporting primary production in microbial mats, which form a habitat-specific trophic base of the whole Basiluzzo hydrothermal ecosystem, including macrobenthic fauna.
Lung Cancer Presenting With Solitary Bone Metastases (1999)

Article Tools DIAGNOSIS IN ONCOLOGY Article Tools OPTIONS & TOOLS Export Citation Track Citation Add To Favorites Rights & Permissions COMPANION ARTICLES No companion articles ARTICLE CITATION DOI: 10.1200/JCO.1999.17.9.2998 Journal of Clinical Oncology - published online before print September 21, 2016 PMID: 10561378 Lung Cancer Presenting With Solitary Bone Metastases Pasi A. JännexPasi A. JänneSearch for articles by this author , Milton W. DattaxMilton W. DattaSearch for articles by this author , Bruce E. JohnsonxBruce E. JohnsonSearch for articles by this author Show More Lowe Center for Thoracic Oncology, Department of Adult Oncology, Dana Farber Cancer Institute, and Departments of Pathology and Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA https://doi.org/10.1200/JCO.1999.17.9.2998 First Page Full Text PDF Figures and Tables © 1999 by American Society of Clinical Oncology
MR imaging artifacts, ferromagnetism, and magnetic torque of intravascular filters, stents, and coils. (1988)

Experiments were conducted in which various intravascular filters, stents, and coils were imaged using magnetic resonance (MR) spin-echo technique at 0.35 T. These devices were also evaluated for ferromagnetism (at 0.35, 1.5, and 4.7 T), magnetic torque (at 0.35 and 1.5 T), and magnetically induced migration within a plastic tube (at 0.35 and 1.5 T for the Greenfield filter [GF]). The stainless-steel GF was evaluated in vitro for its propensity to perforate canine inferior venae cavae (IVC). Magnetic force and torque at 1.5 T did not dislodge the GF or result in perforation of canine IVC by the GF. Beta-3 titanium alloy (used in a new percutaneous version of the GF) is apparently one of the best-suited metals for use with MR imaging because of its lack of ferromagnetism (up to 4.7 T) and absence of MR imaging artifacts (at 0.35 T). Devices composed of Elgiloy (Mobin-Uddin filter), nitinol, and MP32-N (Amplatz filter) alloys all created mild artifacts. Devices fashioned from 304 and 316L (GF and Palmaz stent) stainless-steel alloys created severe "black-hole" artifacts, with the 304 alloy devices also showing marked image distortion. Generally, the greater the ferromagnetism of a device, the greater its magnetic susceptibility artifact.
Could Oxidative Stress Associate with Age Products in Cataractogenesis? (2008)

This study revealed that increased AGEs were associated with oxidative stress in the elderly groups. AGE, as a result of oxidative stress, might have a role in cataract formation, which, in diabetic patients, occurs vigorously as compared with non-diabetic cataract patients.
Enhanced Luminescence Performance of Quantum Wells by Coupling Piezo-Phototronic with Plasmonic Effects (2016)

With a promising prospect of light-emitting diodes as an attractive alternative to conventional light sources, remaining challenges still cannot be addressed owing to their limited efficiency. Among the continued scientific efforts, significant improvement on the emission efficiency has been achieved via either piezo-phototronic effect-based strain modulation or resonant excitation of plasmons in metallic nanostructures. Here, we present the investigation on the coupling process between piezo-phototronic effect and localized surface plasmonic resonance for enhancing the photoluminescence of InGaN/GaN quantum wells coated with Ag nanoparticles. The underlying physical mechanism of experimental results originates from tuning plasmonic resonance controlled by the shift of emission wavelength via piezo-phototronic effect, and it is further confirmed with the support of theoretical calculations. As a result, our research provides an approach to the integration of plasmonics with piezo-phototronic effect and brings widespread applications to high-efficiency artificial lighting, on-chip integrated plasmonic circuits, subwavelength optical communication, and micro-optoelectronic mechanical systems.
Chemical Recycling of Poly(Cyclohexene Carbonate) Using a Di‐Mg<sup>II</sup> Catalyst (2022)

Abstract Chemical recycling of polymers to true monomers is pivotal for a circular plastics economy. Here, the first catalyzed chemical recycling of the widely investigated carbon dioxide derived polymer, poly(cyclohexene carbonate), to cyclohexene oxide and carbon dioxide is reported. The reaction requires dinuclear catalysis, with the di‐Mg II catalyst showing both high monomer selectivity (&gt;98 %) and activity (TOF=150 h −1 , 0.33 mol %, 120 °C). The depolymerization occurs via a chain‐end catalyzed depolymerization mechanism and DFT calculations indicate the high selectivity arises from Mg‐alkoxide catalyzed epoxide extrusion being kinetically favorable compared to cyclic carbonate formation.
Intracellular Delivery and Triggered Release of DNA Using Biodegradable Poly(2‐hydroxypropylene imine)s Containing Cystamine Units (2016)

Poly(2-hydroxypropylene imine)s containing segments of cystamine (PHPI-CA) are synthesized by polycondensation of 1,3-dibromo-2-propanol with a mixture of 1,3-diamino-2-propanol and cystamine. High molecular weight fractions of these polymers are collected by ultrafiltration and characterized by chemical analysis, <sup>1</sup> H and <sup>13</sup> C-NMR spectroscopy, size-exclusion chromatography with triple detection, and potentiometric titration, and are tested for DNA delivery in vitro. It is shown that PHPI-CA are highly branched polymers containing disulfide linkages. Transfection efficiency of PHPI-CA for DNA gives similar results to that of PHPI with GFP<sup>+</sup> cell percent reaching 80-90%. Cytotoxicity levels for PHPI-CA are lower than that of PHPI. Novel polymers containing different amounts of disulfide linkages are able to disintegrate and release DNA following the treatment with reducing agent 1,4-dithiothreitol. Downstream application of PHPI-CA transfected cells for RNA purification shows that RNA yield is not affected even after the double transfection suggesting that these polymers could be great candidates for in vitro and in vivo transfection.
Comparison of Porcine Brain Tissue with Potential Surrogate Materials Under Quasi-static Compression and Dynamic Mechanical Analysis (2018)

Computational models and physical surrogates can provide important insight into complex biomechanical loadings, such as those leading to mild Traumatic Brain Injury (mTBI). However, accurate material properties are required in order to fully realize the potential of such models. This study compares the material properties of porcine brain tissue with various surrogate materials (0.4%, 0.6%, 0.8% concentration agarose gelatin; 3%, 5%, 10% concentration bovine ballistic gelatin; and Sylgard 527). The quasi-static compression properties and dynamic viscoelastic properties (1–200 Hz) for each material were measured using a Dynamic Mechanical Analyzer (TA Instruments, DMA Q800). The tests were performed at room temperature, using fresh porcine brain tissue samples (less than 15 min post-mortem) obtained from a local abattoir. The quasi-static compression stress-strain curves of 5% concentration was in good agreement with the experimental data, while the remaining tissue surrogates were generally higher in stiffness. In terms of dynamic analysis, the complex modulus of the agar and Sylgard 527 materials were found to be comparable to the porcine brain tissue, while the bovine gelatin diverged at higher frequencies.
Characterizing home wireless performance: The gateway view (2015)

In this paper, we analyze a large dataset of passive wireless measurements and obtain insights about wireless performance. We monitor 167 homes continuously for 4 months from the vantage point of the gateway, which allows us to capture all the activity on the home wireless network. We report on the makeup of the home wireless network, traffic activity, and performance characteristics. We find that in most homes, a small number of devices account for most of the observed traffic volume and the bulk of this traffic activity occurs in the evenings. Studying link performance, we find that overall, the vast majority of transmissions are carried out at high data rates and the wireless networks have good coverage. We find a small number of episodes where performance is poor; a few homes have a disproportionate number of poor performance reports. Investigating further, we observe that most of these are not caused by poor coverage (pointing to network interference). Our results significantly add to the understanding of home wireless networks and will help ISPs to understand their subscriber networks.
Tripartite Entanglement versus Tripartite Nonlocality in Three-Qubit Greenberger-Horne-Zeilinger-Class States (2009)

We analyze the relationship between tripartite entanglement and genuine tripartite nonlocality for three-qubit pure states in the Greenberger-Horne-Zeilinger class. We consider a family of states known as the generalized Greenberger-Horne-Zeilinger states and derive an analytical expression relating the three-tangle, which quantifies tripartite entanglement, to the Svetlichny inequality, which is a Bell-type inequality that is violated only when all three qubits are nonlocally correlated. We show that states with three-tangle less than 1/2 do not violate the Svetlichny inequality. On the other hand, a set of states known as the maximal slice states does violate the Svetlichny inequality, and exactly analogous to the two-qubit case, the amount of violation is directly related to the degree of tripartite entanglement. We discuss further interesting properties of the generalized Greenberger-Horne-Zeilinger and maximal slice states.
A New Antibiotic, Antimycin A<sub>9</sub>, Produced by Streptomyces sp. K01‐0031. (2005)

Abstract For Abstract see ChemInform Abstract in Full Text.
An Ex vivo Investigation on Drug Permeability of Sheep Nasal EpithelialTissue Membranes from the Respiratory and Olfactory Regions (2022)

The presence of olfactory nerves and supporting cells and the gaps between them in the olfactory epithelial tissues may have contributed to the higher permeation of atenolol, but this needs to be further investigated to elucidate the precise mechanism.
P1–062: Alzheimer's disease–like tau neuropathology leads to memory deficits and loss of functional synapses in a novel mutated tau transgenic mouse without any motor deficits (2006)

Tau transgenic mice are valuable models to investigate the role of tau protein in Alzheimer's disease (AD) and other tauopathies. However, motor dysfunction and dystonic posture interfering with behavioral testing are the most common late–life undesirable effects of tau transgenic mice such as any motor impairment severely impairs behavior testing and limits the life span that can be investigated. To generate a novel transgenic model that shows AD–like neuropathology without displaying any motor impairment even in very old mice. We have generated a novel mouse model (THY–Tau22) using the 4–repeat tau isoform htau46 (2+3–10+), which is one of the major tau isoforms in human brain. The construct was mutated at sites G272V and P301S and is expressed under a thy1–promotor. This novel tau model displays AD–like tau pathology in the absence of any motor dysfunction. The transgene is found in high concentrations in cortex, hippocampus and amygdala but only traces in the spinal cord. THY–Tau22 shows hyperphosphorylation of tau on several AD–relevant tau epitopes (AT8, AT100, AT180, AT270, tau–pSer396 and tau–pSer422) and neurofibrillary tangle–like inclusions (Gallyas and MC1–positive) starting from 3–6 months of age accompanied by a mild astrogliosis. In addition activated microglia accumulates in the near vicinity to phospho–tau. These mice also display deficits in hippocampal basal synaptic transmission at 14 months while long term potentition (LTP) is not affected at 3 and 14 months indicating a loss of functional synapses. These pathophysiological observations are associated with an impaired behavior characterized by an increased anxiety at 6 months, delayed learning from 3 months and reduced spatial memory at 10 months. There are no signs of motor deficits or any changes in motor activity over all ages investigated. This mouse model displays the main features of tau pathology and several of the pathophysiological disturbances observed in AD and it is the first tau mouse model without displaying any motor deficits. It will serve as an experimental tool in future studies to investigate mechanisms underlying cognitive deficits in AD during pathogenic tau aggregation.
An evaluation of neurophysiological criteria used in the diagnosis of motor neuron disease (2010)

Accepting EMG evidence of fasciculations as evidence of acute denervation increases the diagnostic certainty of MND, and the new criteria allow earlier diagnosis of MND without increasing the false-positive rate.
A spline-based spatial impulse response simulator (2021)

The spatial impulse response (SIR) method is a well-known approach to calculate transient acoustic fields of arbitrary-shape transducers. It involves the evaluation of a time-dependent surface integral. Although analytic expressions of the SIR exist for some geometries, numerical methods based on the discretization of transducer surfaces have become the standard. The proposed method consists of representing the transducer as a non-uniform rational B-spline (NURBS) surface, and decomposing it into smooth Bézier patches onto which quadrature rules can be deployed. The evaluation of the SIR can then be expressed in B-spline bases, resulting in a sum of shifted-and-weighted basis functions. Field signals are eventually obtained by a convolution of the basis coefficients, derived from the excitation waveform, and the basis SIR. The use of NURBS enables exact representations of common transducer elements. High-order Gaussian quadrature rules enable high accuracy with few quadrature points. High-order B-spline bases are ideally suited to exploit efficiently the bandlimited property of excitation waveforms. Numerical experiments demonstrate that the proposed approach enables sampling the SIR at low sampling rates, as required by the excitation waveform, without introducing additional errors on simulated field signals.
Abstract 3038: Influence Of Beta-blockade On Mitral Regurgitant Volume In Patients With Degenerative Mitral Valve Prolapse (2007)

Introduction: Beta-blockers may be indicated for treatment of hypertension or atrial arrhythmias in patients with degenerative mitral valve prolapse (MVP) and moderate-severe mitral regurgitation (MR). However the influence of beta-blockade on the mitral regurgitant volume is uncertain. Methods: The influence of metoprolol on regurgitant volume was studied in 25 asymptomatic patients with moderate-severe MR due to MVP in a randomized double-blind cross over study. Metoprolol or placebo were titrated by an independent investigator according to symptoms, blood pressure and resting heart rate (mean dose 119mg, range 23.75 to 195mg/day). Severity of MR was assessed by cardiac magnetic resonance imaging (MRI) and echo-Doppler after 10 –14 days on each treatment. Regurgitant fraction was calculated using MRI from the difference between stroke volume by LV volumetry and aortic forward flow by phase contrast analysis. Results. Conclusion: Although metoprolol decreased heart rate and systolic blood pressure it does not influence the mitral regurgitant volume in patients with degenerative mitral valve prolapse.
HOMOLOGUS PARTIAL SEQUENCES IN DEHYDROGENASES (1981)

Conference Abstract| April 01 1981 HOMOLOGUS PARTIAL SEQUENCES IN DEHYDROGENASES Gy. Mátrai; Gy. Mátrai 1Inst.Enzymol., Biol. Res. Cent., Hung. Acad. Sci., Budapest, HUNGARY Search for other works by this author on: This Site PubMed Google Scholar F. Darvas; F. Darvas 1Inst.Enzymol., Biol. Res. Cent., Hung. Acad. Sci., Budapest, HUNGARY Search for other works by this author on: This Site PubMed Google Scholar T. Keleti T. Keleti 1Inst.Enzymol., Biol. Res. Cent., Hung. Acad. Sci., Budapest, HUNGARY Search for other works by this author on: This Site PubMed Google Scholar Biochem Soc Trans (1981) 9 (2): 264P. https://doi.org/10.1042/bst009264pb Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter LinkedIn Cite Icon Cite Get Permissions Citation Gy. Mátrai, F. Darvas, T. Keleti; HOMOLOGUS PARTIAL SEQUENCES IN DEHYDROGENASES. Biochem Soc Trans 1 April 1981; 9 (2): 264P. doi: https://doi.org/10.1042/bst009264pb Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsBiochemical Society Transactions Search Advanced Search This content is only available as a PDF. © 1981 Biochemical Society1981 Article PDF first page preview Close Modal You do not currently have access to this content.
Identification of a Divergent Environmental DNA Sequence Clade Using the Phylogeny of Gregarine Parasites (Apicomplexa) from Crustacean Hosts (2011)

This expanded molecular phylogenetic context enabled us to establish a major clade of intestinal gregarine parasites and infer the cellular identities of several previously unidentified environmental SSU rDNA sequences, including several sequences that have formerly been discussed broadly in the literature as a suspected "novel" lineage of eukaryotes.
Using Noisy Extractions to Discover Causal Knowledge (2017)

Knowledge bases (KB) constructed through information extraction from text play an important role in query answering and reasoning. In this work, we study a particular reasoning task, the problem of discovering causal relationships between entities, known as causal discovery. There are two contrasting types of approaches to discovering causal knowledge. One approach attempts to identify causal relationships from text using automatic extraction techniques, while the other approach infers causation from observational data. However, extractions alone are often insufficient to capture complex patterns and full observational data is expensive to obtain. We introduce a probabilistic method for fusing noisy extractions with observational data to discover causal knowledge. We propose a principled approach that uses the probabilistic soft logic (PSL) framework to encode well-studied constraints to recover long-range patterns and consistent predictions, while cheaply acquired extractions provide a proxy for unseen observations. We apply our method gene regulatory networks and show the promise of exploiting KB signals in causal discovery, suggesting a critical, new area of research.
On Convergence Properties of Joint Optimal Power Control and Transmit-Receive Beamforming in Multi-User MIMO Systems (2006)

We consider SDMA in a multi-user downlink MIMO system with several access points, each serving one or more users. The problem of minimizing the total transmitted power satisfying the SINR requirements at all users is considered. This is a non-linear and non-convex optimization problem with three sets of variables: the transmitter powers, the transmitter weights and the receiver weights. Global system knowledge will be assumed at the access points and the provided results can be seen as benchmarks in system performance. We present a new initialization strategy and investigate its convergence behavior for a proposed algorithm. A numerical study is performed to analyze the dependence of the target SINRs on the optimal solution. The performance of this initialization process is evaluated and compared to an existing beamforming algorithm
Metal-free radical perfluoroalkylation of (hetero)arenes (2014)

We report a metal-free radical perfluoroalkylation method which uses inexpensive and commercially available perfluorocarboxylic anhydrides as an easy to use source of perfluoroalkyl radicals.
ChemInform Abstract: DIRECTED LITHIATION OF N,N‐DIETHYLBENZAMIDES. REGIOSPECIFIC ROUTES TO UNSYMMETRICAL ANTHRAQUINONE NATURAL PRODUCTS (1979)

Abstract 3‐Methoxy‐diethylbenzamid (I) liefert nach Metallierung mit Butyllithium mit dem Dimethoxybenzaldehyd (II) ein Phthalid (III), das nach Spaltung zu (IV) zum Anthrol (V) cyclisiert wird.