gebhart/patrepeval huggingface dataset:
Interval Power Flow Analysis Using Linear Relaxation and Optimality-Based Bounds Tightening (OBBT) Methods (2014)

With increasingly large scale of intermittent and non-dispatchable resources being integrated into power systems, the power flow problem presents greater uncertainty. In order to obtain the upper and lower bounds of power flow solutions including voltage magnitudes, voltage angles and line flows, Cartesian coordinates-based power flow is utilized in this paper. A quadratically constrained quadratic programming (QCQP) model is then established to formulate the interval power flow problem. This non-convex QCQP model is relaxed to linear programming problem by introducing convex and concave enclosures of the original feasible region. To improve the solutions bounds while still encompassing the true interval solution, optimality-based bounds tightening (OBBT) method is employed to find a better outer hull of the feasible region. Numerical results on IEEE 9-bus, 30-bus, 57-bus, and 118-bus test systems validate the effectiveness of the proposed method.
Effective Route Scheme of Multicast Probing to Locate High-loss Links in OpenFlow Networks (2021)

The prevalence of cloud computing and contents delivery networking has led to demand for OpenFlow-based centrally-managed networks with dynamic and flexible traffic engineering. Maintaining a high level of network service quality requires detecting and locating high-loss links. Therefore, in this paper, a measurement framework is proposed to promptly locate all high-loss links with a minimized load on both data-plane and control-plane incurred by the measurement, which assumes only standard OpenFlow functions. It combines an active measurement by probing multicast packets along a designed route and a passive measurement by collecting flow-stats of the probing flow at selected switch ports in an appropriate sequential order to access switches. In particular, by designing the measurement route based on the backbone-and-branch tree (BBT) route scheme, the measurement accuracy and the measurement overhead (the number of accesses to switches until locating all high-loss links) can be balanced. The numerical simulation demonstrates the effectiveness of our proposal.
Pilot-Scale Demonstration of Surfactant-Enhanced PCE Solubilization at the Bachman Road Site. 2. System Operation and Evaluation (2005)

A pilot-scale demonstration of surfactant-enhanced aquifer remediation (SEAR) was conducted during the summer of 2000 at the Bachman Road site in Oscoda, MI. Part two of this two-part paper describes results from partitioning and nonpartitioning tracer tests, SEAR operations, and post-treatment monitoring. For this field test, 68 400 L of an aqueous solution of 6% (wt) Tween 80 were injected to recover tetrachloroethene-nonaqueous phase liquid (PCE-DNAPL) from a shallow, unconfined aquifer. Results of a nonreactive tracer test, conducted prior to introducing the surfactant solution, demonstrate target zone sweep and hydraulic control, confirming design-phase model predictions. Partitioning tracer test results suggest PCE-DNAPL saturations of up to 0.74% within the pilot-scale treatment zone, consistent with soil core data collected during site characterization. Analyses of effluent samples taken from the extraction well during SEAR operations indicate that a total of 19 L of PCE and 95% of the injected surfactant were recovered. Post-treatment monitoring indicated that PCE concentrations at many locations within the treated zone were reduced by as much as 2 orders of magnitude from pre-SEAR levels and had not rebounded 450 days after SEAR operations ceased. Pilot-scale costs ($365 900) compare favorably with design-phase cost estimates, with approximately 10% of total costs attributable to the intense sampling density and frequency. Results of this pilot-scale test indicate that careful design and implementation of SEAR can result in effective DNAPL mass removal and a substantial reduction in aqueous concentrations within the treated source zone under favorable geologic conditions
Coriolis Effect in Optics: Unified Geometric Phase and Spin-Hall Effect (2008)

We examine the spin-orbit coupling effects that appear when a wave carrying intrinsic angular momentum interacts with a medium. The Berry phase is shown to be a manifestation of the Coriolis effect in a noninertial reference frame attached to the wave. In the most general case, when both the direction of propagation and the state of the wave are varied, the phase is given by a simple expression that unifies the spin redirection Berry phase and the Pancharatnam-Berry phase. The theory is supported by the experiment demonstrating the spin-orbit coupling of electromagnetic waves via a surface plasmon nanostructure. The measurements verify the unified geometric phase, demonstrated by the observed polarization-dependent shift (spin-Hall effect) of the waves.
ChemInform Abstract: Bridged Cyanine Dyes. Part 1. 1‐(N‐Methyl‐4‐pyridinio)‐3‐(N‐methylpyridylene)cyclopenta‐1,4‐dienes. (1989)

Abstract 1,3‐Bis(4‐pyridyl)propane (I) is bisalkylated with methyl iodide (II), forming the bridged bispyridinium salt (III) which undergoes cyclocondensation with the 1,2‐diones (IV) or the α‐keto esters (VI) to produce the cyanine dyes (V) or (VII) mentioned in the title.
Radiation toxicity in cultured endothelial cells and its effect on transglutaminase activity (1992)

s: First meeting of the European Thrombosis Research Organization Working Party on factor XIII: PDF Only
Characterization of Arabidopsis thaliana Lines with Altered Seed Storage Protein Profiles Using Synchrotron-Powered FT-IR Spectromicroscopy (2013)

Arabidopsis thaliana lines expressing only one cruciferin subunit type (double-knockout; CRUAbc, CRUaBc, or CRUabC) or devoid of cruciferin (triple-knockout; CRU-) or napin (napin-RNAi) were generated using combined T-DNA insertions or RNA interference approaches. Seeds of double-knockout lines accumulated homohexameric cruciferin and contained similar protein levels as the wild type (WT). Chemical imaging of WT and double-knockout seeds using synchrotron FT-IR spectromicroscopy (amide I band, 1650 cm(-1), νC═O) showed that proteins were concentrated in the cell center and protein storage vacuoles. Protein secondary structure features of the homohexameric cruciferin lines showed predominant β-sheet content. The napin-RNAi line had lower α-helix content than the WT. Lines entirely devoid of cruciferin had high α-helix and low β-sheet levels, indicating that structurally different proteins compensate for the loss of cruciferin. Lines producing homohexameric CRUC showed minimal changes in protein secondary structure after pepsin treatment, indicating low enzyme accessibility. The Synchrotron FT-IR technique provides information on protein secondary structure and changes to the structure within the cell.
Influence of Ordering in Porous TiO<sub>2</sub> Layers on Electron Diffusion (2006)

Layers of porous TiO(2) fabricated by electrophoretic deposition at different temperatures with subsequent sintering in air were investigated by transient photocurrent measurements in aqueous electrolyte. The effective diffusion coefficient of excess electrons changed between 1.6 x 10(-5) and 1.4 x 10(-4) cm(2)/s depending strongly on the solution temperature during the TiO(2) layer deposition. Characterization, in terms of average degree of preferred orientation, shows that low deposition temperature results in orientation of the nanocrystals forming the porous film. Consequently, the increase of effective diffusion coefficient is attributed to a higher degree of ordering in the nanoporous TiO(2) layer.
Understanding and Targeting the Endocannabinoid System with Activity‐Based Protein Profiling (2023)

Abstract The endocannabinoid system (ECS) is a widespread modulatory system composed of cannabinoid receptors, endogenous signaling lipids termed endocannabinoids and the enzymes for the biosynthesis and degradation of these endocannabinoids. It plays a crucial role in diverse (patho)physiological functions, such as neurotransmission, neural development, synaptic plasticity, mood, food intake, and inflammation. Enzymes involved in the biosynthesis (e. g. NAPE‐PLD, DAGLs) and degradation (e. g. FAAH, MAGL) of endocannabinoids have attracted attention from both academia and industry due to their therapeutic potential. The discovery of selective inhibitors for these enzymes is important for functional assignment and biomedical applications. Activity‐based protein profiling (ABPP) has emerged as a powerful technique, which to a large extend accelerated the development of selective inhibitors for ECS enzymes. This review summarizes the representative activity‐based probes (ABPs) and small molecular inhibitors developed in the past two decades for ECS enzymes and will discuss the biological discoveries attributed by the application of these small molecules.
Control schemes for VLSI microprocessors (1982)

As microprocessors move into the VLSI era, the number and complexity of the functions they are expected to perform increases beyond the capability of conventional control schemes. This paper discusses the fundamental requirements of such a control system, and explores the possibility of using external microcode control.
Genetic dissection of plant cell-wall biosynthesis (2002)

The plant cell wall is a complex structure consisting of a variety of polymers including cellulose, xyloglucan, xylan and polygalacturonan. Biochemical and genetic analysis has made it possible to clone genes encoding cellulose synthases (CesA). A comparison of the predicted protein sequences in the Arabidopsis genome indicates that 30 divergent genes with similarity to CesAs exist. It is possible that these cellulose synthase-like (Csl) proteins do not contribute to cellulose synthesis, but rather to the synthesis of other wall polymers. A major challenge is, therefore, to assign biological function to these genes. In an effort to address this issue we have systematically identified T-DNA or transposon insertions in 17 Arabidopsis Csls. Phenotypic characterization of "knock-out" mutants includes the determination of spectroscopic profile differences in mutant cell walls from wild-type plants by Fourier-transform IR microscopy. A more precise characterization includes cell wall fractionation followed by neutral sugar composition analysis by anionic exchange chromatography.
Experimental Validation of Model Predictive Charging Pressure and EGR Rate Control for an SI Engine (2020)

Turbocharged spark-ignition (SI) engines with low pressure exhaust gas recirculation (EGR) offer a favorable potential to meet strict pollutant emission limits under real-driving conditions. While complex air path concepts with EGR are already state-of-the-art for diesel engines, the application for SI engines is still a topic of research. Due to the air-quantity-based engine load control as well as the potential occurrence of knocking combustion, a precise boost pressure and EGR rate control is decisive for a reliable operation. Within the scope of this paper, various model predictive control (MPC) concepts for turbocharged SI engines with EGR are proposed. For the evaluation, a prototype vehicle is equipped with a serial sequential turbocharging system as well as a low pressure EGR path. To control this overactuated multiple-input-multiple-output system with variable dead times, a linear as well as a nonlinear model predictive controller are developed. The benefit of utilizing a model of the EGR sensor dynamics within the observer is additionally examined. The control behavior is validated by performing tip-in tests with the vehicle on a test track. The results are evaluated considering overshoot, the time to reach the respective setpoints as well as steady-state accuracy.
Trash-ICRA19: A bounding box labeled dataset of underwater trash (2018)

This data was sourced from the J-EDI dataset of marine debris. The videos that comprise that dataset vary greatly in quality, depth, objects in scenes, and the cameras used. They contain images of many different types of marine debris, captured from real-world environments, providing a variety of objects in different states of decay, occlusion, and overgrowth. Additionally, the clarity of the water and quality of the light vary significantly from video to video. These videos were processed to extract 5,700 images, which comprise this dataset, all labeled with bounding boxes on instances of trash, biological objects such as plants and animals, and ROVs. The eventual goal is to develop efficient and accurate trash detection methods suitable for onboard robot deployment. It is our hope that the release of this dataset will facilitate further research on this challenging problem, bringing the marine robotics community closer to a solution for the urgent problem of autonomous trash detection and removal.
Ionic liquids for efficient hydrogen sulfide and thiol scavenging (2014)

Functionalised pyridinium and ammonium ionic liquids bearing a Michael acceptor are shown to scavenge H<sub>2</sub>S gas and various thiols, in most cases, without the aid of any added bases. Utilising the effective non-volatility of ionic liquids and ‘tagging’ malodourous substances to an ionic matrix renders them odourless.
The Novel Oxazolidinone TBI-223 Is Effective in Three Preclinical Mouse Models of Methicillin-Resistant Staphylococcus aureus Infection (2022)

Staphylococcus aureus is an important cause of various infections in humans, including bacteremia, skin and soft tissue infections, and infections associated with implanted medical devices. The emergence of hospital- and community-acquired methicillin-resistant Staphylococcus aureus (MRSA) underscores the urgent and unmet need to develop novel, safe, and effective antibiotics against these multidrug-resistant clinical isolates. Oxazolidinone antibiotics such as linezolid have excellent oral bioavailability and provide coverage against MRSA infections. However, their widespread and long-term use is often limited by adverse effects, especially myelosuppression. TBI-223 is a novel oxazolidinone with potentially reduced myelosuppression, compared to linezolid, but its efficacy against MRSA infections is unknown. Therefore, the preclinical efficacy of TBI-223 (80 and 160 mg/kg twice daily) was compared with that of linezolid (40 and 80 mg/kg twice daily) and sham treatment in mouse models of MRSA bacteremia, skin wound infection, and orthopedic-implant-associated infection. The dosage was selected based on mouse pharmacokinetic analysis of both linezolid and TBI-223, as well as measurement of the MICs. In all three models, TBI-223 and linezolid had comparable dose-dependent efficacies in reducing bacterial burden and disease severity, compared with sham-treated control mice. Taken together, these findings indicate that TBI-223 represents a novel oxazolidinone antibiotic that may provide an additional option against MRSA infections. Future studies in larger animal models and clinical trials are warranted to translate these findings to humans. <b>IMPORTANCE</b> Staphylococcus aureus is the predominant cause of bloodstream, skin, and bone infections in humans. Resistance to commonly used antibiotics is a growing concern, making it more difficult to treat staphylococcal infections. Use of the oxazolidinone antibiotic linezolid against resistant strains is hindered by high rates of adverse reactions during prolonged therapy. Here, a new oxazolidinone named TBI-223 was tested against S. aureus in three mouse models of infection, i.e., bloodstream infection, skin infection, and bone infection. We found that TBI-223 was as effective as linezolid in these three models. Previous data suggest that TBI-223 has a better safety profile than linezolid. Taken together, these findings indicate that this new agent may provide an additional option against MRSA infections. Future studies in larger animal models and clinical trials are warranted to translate these findings to humans.
A fast design method for orthogonal modulated filter banks (2002)

A method is proposed to solve the unconstrained optimization problem related to the design of perfect reconstruction modulated filter banks. The basic idea is to take advantage of certain attractive properties of the angular parametrization of the underlying lattice structure. This approach allows the design of prototypes with thousands of coefficients. Nearly optimal results are presented for two different optimization criteria.
The Impact of B Lymphocyte Depletion on the Pathogenesis of Autoimmune Diabetes (131.28) (2007)

Abstract NOD B cell development is characterized by a defective homeostatic checkpoint in B cell maturation and selection. Having demonstrated that the progression of autoimmune diabetes requires antigen presentation by B-lymphocytes, we hypothesized that B cell depletion may prevent diabetes progression in NOD mice. Here, we employed two distinct approaches for in vivo B lymphocyte depletion: a cohort of adult hCD20 Tg NOD mice were treated with the B lymphocyte depleting mAb, Rituximab (anti-CD20) and a cohort of adult NOD mice were treated with a neutralizing Hamster anti-mouse mAb specific for the B cell survival factor, BLyS/BAFF. Treatment with both Rituximab (2mg/injection x3doses) and anti-BLyS mAb (100?g/injection x2 doses) led to B cell depletion within 10 days. BLyS/BAFF neutralization, using anti-BLyS, caused a profound depletion of mature/recirculating B cells in these mice and lasted for &amp;gt;30 days. Diabetes occurred within 2 weeks in all Rituximab treated female hCD20 Tg NOD mice (n=4); despite their early backcross generations (i.e., N4-6F1) onto the NOD genetic background. Conversely, adult female NOD/LtJ mice (n=20), B cell depleted using anti-BLyS/BAFF did not progress to diabetes for &amp;gt;30 days following treatment. Collectively, these results indicate that BLyS/BAFF neutralization may be required for the prevention of autoimmune diabetes following B lymphocyte depletion.
Oligo(<i>p</i>-phenylenevinylene)−Peptide Conjugates: Synthesis and Self-Assembly in Solution and at the Solid−Liquid Interface (2008)

Two oligo(p-phenylenevinylene)-peptide hybrid amphiphiles have been synthesized using solid- and liquid-phase strategies. The amphiliphiles are composed of a pi-conjugated oligo(p-phenylenevinylene) trimer (OPV) which is coupled at either a glycinyl-alanyl-glycinyl-alanyl-glycine (GAGAG) silk-inspired beta-sheet or a glycinyl-alanyl-asparagyl-prolyl-asparagy-alanyl-alanyl-glycine (GANPNAAG) beta-turn forming oligopeptide sequence. The solid-phase strategy enables one to use longer peptides if strong acidic conditions are avoided, whereas the solution-phase coupling gives better yields. The study of the two-dimensional (2D) self-assembly of OPV-GAGAG by scanning tunneling microscopy (STM) at the submolecular level demonstrated the formation of bilayers in which the molecules are lying antiparallel in a beta-sheet conformation. In the case of OPV-GANPNAAG self-assembled monolayers could not be observed. Absorption, fluorescence, and circular dichroism studies showed that OPV-GAGAG and OPV-GANPNAAG are aggregated in a variety of organic solvents. In water cryogenic temperature transmission electron microscopy (cryo-TEM), atomic force microscopy (AFM), light scattering, and optical studies reveal that self-assembled nanofibers are formed in which the helical organization of the OPV segments is dictated by the peptide sequence.
A Unified Approach to Integral Formulations for Electromagnetic Scattering. (1991)

This paper discusses pollution of surface water in 18 European countries. For each an account is given of its physical character, population, industries, and present condition of water supplies; the legal, administrative, and technical means of controlling pollution are then described, and an outline is given of current research on the difficulties peculiar to each country. A general discussion of various aspects common to the European problem of water pollution follows; standards of quality are suggested; some difficulties likely to arise in the near future are indicated, and international collaboration, primarily by the exchange of information, is recommended to check or forestall these trends.
Genetic characterization of melon accessions in the U.S. National Plant Germplasm System and construction of a melon core collection (2021)

Melon (C. melo L.) is an economically important vegetable crop cultivated worldwide. The melon collection in the U.S. National Plant Germplasm System (NPGS) is a valuable resource to conserve natural genetic diversity and provide novel traits for melon breeding. Here we use the genotyping-by-sequencing (GBS) technology to characterize 2083 melon accessions in the NPGS collected from major melon production areas as well as regions where primitive melons exist. Population structure and genetic diversity analyses suggested that C. melo ssp. melo was firstly introduced from the centers of origin, Indian and Pakistan, to Central and West Asia, and then brought to Europe and Americas. C. melo ssp. melo from East Asia was likely derived from C. melo ssp. agrestis in India and Pakistan and displayed a distinct genetic background compared to the rest of ssp. melo accessions from other geographic regions. We developed a core collection of 383 accessions capturing more than 98% of genetic variation in the germplasm, providing a publicly accessible collection for future research and genomics-assisted breeding of melon. Thirty-five morphological characters investigated in the core collection indicated high variability of these characters across accessions in the collection. Genome-wide association studies using the core collection panel identified potentially associated genome regions related to fruit quality and other horticultural traits. This study provides insights into melon origin and domestication, and the constructed core collection and identified genome loci potentially associated with important traits provide valuable resources for future melon research and breeding.
Induction of Lysosomal Biogenesis in Atherosclerotic Macrophages Can Rescue Lipid-Induced Lysosomal Dysfunction and Downstream Sequelae (2014)

Taken together, these data demonstrate that lysosomal function is markedly impaired in atherosclerosis and suggest that induction of a lysosomal biogenesis program in macrophages has antiatherogenic effects.
Supplementary Figure 1 from The Role of ATF4 Stabilization and Autophagy in Resistance of Breast Cancer Cells Treated with Bortezomib (2023)

Supplementary Figure 1 from The Role of ATF4 Stabilization and Autophagy in Resistance of Breast Cancer Cells Treated with Bortezomib
Diffusion dynamics of small molecules from mesoporous silicon films by real-time optical interferometry (2011)

Time-dependent laser reflectometry measurements are presented as a means to rigorously characterize analyte diffusion dynamics of small molecules from mesoporous silicon (PSi) films for drug delivery and membrane physics applications. Calculations based on inclusion of a spatially and temporally dependent solute concentration profile in a one-dimensional Fickian diffusion flow model are performed to determine the diffusion coefficients for the selected prototypical polar species, sucrose (340 Da), exiting from PSi films. The diffusion properties of the molecules depend on both PSi pore size and film thickness. For films with average pore diameters between 10-30 nm and film thicknesses between 300-900 nm, the sucrose diffusion coefficient can be tuned between approximately 100 and 550 μm2/s. Extensions of the real-time measurement and modeling approach for determining the diffusivity of small molecules that strongly interact with and corrode the internal surfaces of PSi films are also discussed.