gebhart/patrepeval huggingface dataset:
The Effect of a Monocular Helmet-Mounted Display on Aircrew Health: A Cohort Study of Apache AH Mk1 Pilits Two-Year Baseline Review (2004)

Abstract : This is the first interim report for the study titled The Effect of a Monocular Helmet-Mounted Display on Aircrew Health: A Cohort Study of Apache AH Mk 1 Pilots. The principal aim of this occupational health study is to determine if the use of the monocular Integrated Helmet and Display Sighting System (IHADSS) helmet-mounted display (HMD) in the British Army's Apache AH Mk 1 attack helicopter has any long-term effect on visual performance. Additional information concerning other unique problems of the Apache AH Mk 1 aircrew is elicited as a secondary objective. This study is a collaborative effort between the British Army and the U.S. Army and is conducted under the auspices of The Technical Cooperative Program (TTCP), Subgroup U, Technical Panel 7 (Human Factors in the Aviation Environment).
Table S1 from PSMA-positive Circulating Tumor Cell Detection and Outcomes with Abiraterone or Enzalutamide Treatment in Men with Metastatic Castrate-resistant Prostate Cancer (2023)

&lt;p&gt;Comparison of CTC enumeration and PSMA+ CTC expression in 57 baseline and paired progression samples from the PROPHECY study. All the CTC parameters (mean, median, and range) were represent in CTC/mL.&lt;/p&gt;
Synthesis of Lithium 1-Alkynesulfenates by the Mild Oxidation of Thiolates with a Pinacolone-Derived <i>N</i>-Sulfonyloxaziridine (2006)

Lithium 1-alkynethiolates, generated by a base-induced ring cleavage of 4-substituted 1,2,3-thiadiazoles, were efficiently converted into the corresponding sulfenate salts by mild oxidation using an N-sulfonyloxaziridine derived from pinacolone. In situ S-alkylation with alkyl halides led to α,β-acetylenic sulfoxides.
<i>Bacillus thuringiensis</i>Cytolytic Toxin Associates Specifically with Its Synthetic Helices A and C in the Membrane Bound State. Implications for the Assembly of Oligomeric Transmembrane Pores (1997)

The CytA toxin exerts its activity by the formation of pores within target cell membranes. However, the exact mechanism of pore formation and the structural elements that are involved in the toxic activity are yet to be determined. Recently, the structure of the highly similar CytB toxin was solved (Li et al., 1996), and a beta-barrel was suggested as a possible structure of the pores. Due to the similarity between the toxins, the existence and positioning of alpha-helices and beta-sheets in CytA were predicted from the alignment of the sequences. Here peptides corresponding to beta5, beta6, and beta7 strands, to a conserved nonhelical region of the CytA toxin (P149-170), to helices B and D, and to an analogue of helix A were synthesized, fluorescently labeled, and characterized. We found that, unlike helices A and C (Gazit and Shai, 1993), neither the beta-strand peptides nor helix B could interact with lipid membranes, whereas P149-170 and helix D bind the membrane weakly. Membrane permeation experiments suggested that CytA toxin exerts its activity by aggregation of several monomers. To learn about the structural elements that may mediate CytA oligomerization, the ability of the synthetic peptides to interact with membrane-bound CytA was studied. Helices A and C, but not the beta-strands, helix D, or a control peptide, caused a large increase in the fluorescence of membrane-bound fluorescein-labeled CytA, whereas helix B had only a slight effect. Moreover, the addition of rearranged helix A, a peptide with the same composition as helix A, but with only two pairs of amino acids rearranged, did not affect the fluorescence. The addition of unlabeled CytA also caused an increase in the fluorescence intensity, further demonstrating the interaction between CytA monomers within the membrane. Taken together, our results provide further support for the suggestion that the CytA toxin self-assembles within membrane and that helices A and C are major structural elements involved in the membrane interaction and intermolecular assembly of the toxin.
Novel Sulfur and Carbon Highly Tolerant Current Collecting Materials for Solid Oxide Fuel Cell (2013)

Abstract not Available.
Flow Separation Within the Engine Inlet of an Uninhabited Combat Air Vehicle (UCAV) (2004)

This paper discusses the structure of the flow within the engine inlet of an uninhabited combat air vehicle (UCAV). The UCAV features a top-mounted, serpentine inlet leading to an engine buried within the fuselage. The performance of the inlet is found to depend strongly on a flow separation that occurs within the inlet. Both the time-averaged and the unsteady structure of this separation is studied, and an argument relating the inlet performance to the behavior of this separation is suggested. The results presented in this paper also suggest that there are considerable aerodynamic limitations to further shortening or narrowing of the inlet. Since there are substantial, system level benefits from using a smaller inlet, the case for separated flow control therefore appears clear.
Scene Invariant Crowd Segmentation and Counting Using Scale-Normalized Histogram of Moving Gradients (HoMG) (2016)

The problem of automated crowd segmentation and counting has garnered significant interest in the field of video surveillance. This paper proposes a novel scene invariant crowd segmentation and counting algorithm designed with high accuracy yet low computational complexity in mind, which is key for widespread industrial adoption. A novel low-complexity, scale-normalized feature called Histogram of Moving Gradients (HoMG) is introduced for highly effective spatiotemporal representation of individuals and crowds within a video. Real-time crowd segmentation is achieved via boosted cascade of weak classifiers based on sliding-window HoMG features, while linear SVM regression of crowd-region HoMG features is employed for real-time crowd counting. Experimental results using multi-camera crowd datasets show that the proposed algorithm significantly outperform state-of-the-art crowd counting algorithms, as well as achieve very promising crowd segmentation results, thus demonstrating the efficacy of the proposed method for highly-accurate, real-time video-driven crowd analysis.
Emotional Expression Classification Using Time-Series Kernels (2013)

Estimation of facial expressions, as spatio-temporal processes, can take advantage of kernel methods if one considers facial landmark positions and their motion in 3D space. We applied support vector classification with kernels derived from dynamic time-warping similarity measures. We achieved over 99% accuracy - measured by area under ROC curve - using only the 'motion pattern' of the PCA compressed representation of the marker point vector, the so-called shape parameters. Beyond the classification of full motion patterns, several expressions were recognized with over 90% accuracy in as few as 5-6 frames from their onset, about 200 milliseconds.
Rapid Identification of <i>Campylobacter</i> spp. by Melting Peak Analysis of Biprobes in Real-Time PCR (2001)

We describe rapid PCR-biprobe identification of Campylobacter spp. This is based on real-time PCR with product analysis in the same system. The assay identifies enteropathogenic campylobacters to the species level on the basis of their degree of hybridization to three 16S ribosomal DNA (rDNA) biprobes. First-round symmetric PCR is performed with genus-specific primers which selectively target and amplify a portion of the 16S rRNA gene common to all Campylobacter species. Second-round asymmetric PCR is performed in a LightCycler in the presence of one of three biprobes; the identity of an amplified DNA-biprobe duplex is established after determination of the species-specific melting peak temperature. The biprobe specificities were determined by testing 37 reference strains of Campylobacter, Helicobacter, and Arcobacter spp. and 59 Penner serotype reference strains of Campylobacter jejuni and C. coli. From the combination of melting peak profiles for each probe, an identification scheme was devised which accurately detected the five taxa pathogenic for humans (C. jejuni/C. coli, C. lari, C. upsaliensis, C. hyointestinalis, and C. fetus), as well as C. helveticus and C. lanienae. The assay was evaluated with 110 blind-tested field isolates; when the code was broken their previous phenotypic species identification was confirmed in every case. The PCR-biprobe assay also identified campylobacters directly from fecal DNA. PCR-biprobe testing of stools from 38 diarrheic subjects was 100% concordant with PCR-enzyme-linked immunosorbent assay identification (13, 20) and thus more sensitive than phenotypic identification following microaerobic culture.
Microsurgical treatment for hypertensive large basal ganglia hemorrhage (2011)

Objective To investigate the methods and curative effect of microsurgical treatment for hypertensive large basal ganglia hemorrhage.Methods By means of trans-pterion or trans-revised pterion craniotomy and large decompressive craniotomies,transsylvian-transinsular approach is made necessarily by minimally invasive technique,removing intracranial hematoma and withholding bleeding under microscope for 60 patients of hypertensive basal ganglia hemorrhage.Then follow-up for 6—24 months after the operation,clinical outcome and prognosis were evaluated by Modified Rankin Scale(MRS).Results Five patients died among 60 cases,mortality was 7.1%. None of patients had no symptoms at all(MRS=0),l patient had no significant disability despite symptoms(MRS=l),2 patients had slight disability(MRS=2),19 patients had moderate disability (MRS = 3 ),25 patients had moderately severe disability(MRS = 4 ),8 patients had severe disability(MRS = 5 ).Conclusions Trans-pterion or trans-revised pterion craniotomy,large decompressive craniotomies were necessary,transsylvian-transinsular approach was made by minimally invasive technique,so as to remove intracranial hematoma and withhold bleeding under microscope for hypertensive basal ganglia hemorrhage complicated with cerebral herniation may be advocated.
Error-Resilient Video Transmission for Short-Range Point-to-Point Wireless Communication (2010)

In this paper, we present a novel error resiliency approach for short-range point-to-point wireless video transmission systems that have particularly stringent delay constraints. We propose to utilize per-packet feedback information that can be generated and transmitted instantaneously from the receiver to the transmitter in such systems to help control the transmission errors. A framework for error resilient video transmission under low-latency constraints is presented, which incorporates the instantaneous feedback into the video encoder to stop error propagation, as well as into a channel adaptive retransmission scheme at the transmitter to reduce the residual packet loss rate. The channel adaptive retransmission scheme is integrated into the system without introducing any additional delay, which is achieved by dynamically adjusting the resource allocation between video source coding and retransmission, where different resource allocation strategies are applied for different channel conditions. The performance of the proposed framework is evaluated in a real-time video transmission system, showing significant video quality improvements for a wide range of channel conditions.
Towards Understanding the Polycystins (2003)

Autosomal dominant polycystic kidney disease (ADPKD) is a very common inherited disease caused by mutations in PKD1 or PKD2 genes characterized by progressive enlargement of fluid-filled cysts and loss of renal function [1]. Previous studies proposed a role for human polycystin-1 in renal morphogenesis acting as a matrix receptor in focal adhesions and for polycystin-2 as a putative calcium channel [2, 3]. The genome of Caenorhabditis elegans contains 2 new members of the polycystin family: lov-1, the homolog for PKD1; and pkd-2, the homolog for PKD2 [4; this paper]. Mutation analysis in C. elegans showed similarly compromised male mating behaviors in all single and double lov-1 and pkd-2 mutants, indicating their participation in a single genetic pathway. Expression analysis localized LOV-1 and PKD-2 to the ends of sensory neurons in male tails and to the tips of CEM neurons in the head, consistent with functions as chemo- or mechanosensors. Human and C. elegans PKD1 and PKD2 homologs, transfected into mammalian renal epithelial cells, co-localized with paxillin in focal adhesions suggesting function in a single biological pathway. Based on the role of polycystins in C. elegans sensory neuron function and the conservation of PKD pathways we suggest that polycystins act as sensors of the extracellular environment, initiating, via focal adhesion assembly, intracellular transduction events in neuronal or morphogenetic processes.
Integrated analysis of software product lines (2011)

Software Product Line (SPL) is a software development framework to jointly design a family of closely related software products in an efficient and cost-effective manner. In order to separate the concerns and handle complexity, designers usually project the SPL along different perspectives such as feature, architecture and behaviour. Each perspective deals with variability of a set of artifacts and variability constraints among them. SPL designers attempt to ensure the consistency of the individual perspectives and the SPL as a whole. They are also interested in finding the elements common to all products and the live elements (used in at least one product).
The International Retinal Imaging Symposium (IRIS IV) 2016 (2016)

Sarraf, David MD; Fawzi, Amani MD; Sadda, SriniVas MD; Waheed, Nadia MD Author Information
Mechanosensation through integrins: Cells act locally but think globally (2003)

Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans the biological, physical, and social sciences.
STATUS OF THE LBNL NORMAL-CONDUCTING CW VHF ELECTRON PHOTO-GUN* (2010)

The fabrication and installation at the Lawrence Berkeley National Laboratory of a high-brightness high-repetition rate photo-gun, based on a normal conducting 187 MHz (VHF) RF cavity operating in CW mode, is in an advanced phase. The cavity will generate an electric field at the cathode plane of ∼ 20 MV/m to accelerate the electron bunches up to ∼ 750 keV, with peak current, energy spread and transverse emittance suitable for FEL and ERL applications. The gun vacuum system has been designed for achieving pressures compatible with the use of "delicate" high quantum efficiency semiconductor cathodes to generate up to a nC bunches at MHz repetition rate with present laser technology. Several photo-cathode/laser systems are under consideration, and in particular photo-cathodes based on K2CsSb are being developed for the gun and have already achieved a QE of 8% at 532 nm wavelength, or close to 20% including the Schottky barrier lowering. The cathode will be operated by a μJ fiber laser in conjunction with refractive transverse beam shaping to create a flat top transverse profile, as well as a birefringent pulse stacker to create a flat top temporal profile. The present status and the plan for future activities are presented.
Deep Learning: A Generic Approach for Extreme Condition Traffic Forecasting (2017)

Traffic forecasting is a vital part of intelligent transportation systems. It becomes particularly challenging due to short-term (e.g., accidents, constructions) and long-term (e.g., peak-hour, seasonal, weather) traffic patterns. While most of the previously proposed techniques focus on normal condition forecasting, a single framework for extreme condition traffic forecasting does not exist. To address this need, we propose to take a deep learning approach. We build a deep neural network based on long short term memory (LSTM) units. We apply Deep LSTM to forecast peak-hour traffic and manage to identify unique characteristics of the traffic data. We further improve the model for post-accident forecasting with Mixture Deep LSTM model. It jointly models the normal condition traffic and the pattern of accidents. We evaluate our model on a real-world large-scale traffic dataset in Los Angeles. When trained end-to-end with suitable regularization, our approach achieves 30%–50% improvement over baselines. We also demonstrate a novel technique to interpret the model with signal stimulation. We note interesting observations from the trained neural network.
A genetic algorithm approach to curve fitting (1995)

Abstract We present a genetic algorithm approach to fitting curves with multiple parameters to data points. Using data from three functions with two to ten coefficients and one to ten variables with linear, polynomial and transcendental functional forms, we varied the number of data points, the range searched over, the distance metric, the distribution for sampling, and the parameters of the genetic algorithm to examine the robustness of the approach. We developed a sequential evolution mechanism to overcome premature convergence to local minima when some terms dominate others in magnitude. Comparison with previously published work is favourable with regard to both goodness of fit and computational effort. Additional informationNotes on contributorsA. E. SMITH To whom correspondence should be addressed.
Antisense to cyclin D1 inhibits the growth and tumorigenicity of human colon cancer cells. (1997)

Cyclin D1 plays an important role in regulating the progression of cells through the G1 phase of the cell cycle. This gene is frequently overexpressed in human colon cancer. To address the role of cyclin D1 in growth control and tumorigenesis in this disease, we have overexpressed an antisense cyclin D1 cDNA construct in the human colon cancer cell line SW480E8, which expresses high levels of cyclin D1. The integration and expression of the antisense construct was verified by Southern and Northern blot analyses, respectively, and resulted in decreased expression of the cyclin D1 protein. This was associated with decreased levels of the Rb and p27Kip1 proteins. In addition, the hypophosphorylated form of Rb was increased in these cells. The SW480E8 antisense cyclin D1 cells displayed an increased doubling time, a decrease in saturation density, decreased plating efficiency and anchorage-independent growth, and a loss of tumorigenicity in nude mice. These findings provide direct evidence that increased expression of cyclin D1 in colon tumor cells contributes to their abnormal growth and tumorigenicity. The ability to revert the transformed phenotype of these cells with antisense cyclin D1 suggests that cyclin D1 or its associated cyclin-dependent kinase 4 may be useful targets in the therapy of colon cancer.
Correction to Tailored Three-Dimensionally Printed Triply Periodic Calcium Phosphate Implants: A Preclinical Study for Craniofacial Bone Repair (2020)

ADVERTISEMENT RETURN TO ISSUEPREVAddition & Corre...Addition & CorrectionNEXTORIGINAL ARTICLEThis notice is a correctionCorrection to Tailored Three-Dimensionally Printed Triply Periodic Calcium Phosphate Implants: A Preclinical Study for Craniofacial Bone RepairArnaud ParéArnaud ParéMore by Arnaud Paréhttp://orcid.org/0000-0001-6060-5077, Baptiste CharbonnierBaptiste CharbonnierMore by Baptiste Charbonnier, Pierre TournierPierre TournierMore by Pierre Tournier, Caroline VignesCaroline VignesMore by Caroline Vignes, Joëlle VeziersJoëlle VeziersMore by Joëlle Veziers, Julie LesoeurJulie LesoeurMore by Julie Lesoeur, Boris LaureBoris LaureMore by Boris Laure, Hélios BertinHélios BertinMore by Hélios Bertin, Gonzague De PinieuxGonzague De PinieuxMore by Gonzague De Pinieux, Grégory CherrierGrégory CherrierMore by Grégory Cherrier, Jérome GuicheuxJérome GuicheuxMore by Jérome Guicheux, Olivier GauthierOlivier GauthierMore by Olivier Gauthier, Pierre CorrePierre CorreMore by Pierre Corre, David MarchatDavid MarchatMore by David Marchat, and Pierre Weiss*Pierre WeissMore by Pierre WeissCite this: ACS Biomater. Sci. Eng. 2020, 6, 3, 1821Publication Date (Web):February 20, 2020Publication History Received3 February 2020Published online20 February 2020Published inissue 9 March 2020https://pubs.acs.org/doi/10.1021/acsbiomaterials.0c00167https://doi.org/10.1021/acsbiomaterials.0c00167correctionACS PublicationsCopyright © 2020 American Chemical Society. This publication is available under these Terms of Use. Request reuse permissions This publication is free to access through this site. Learn MoreArticle Views694Altmetric-Citations1LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail PDF (297 KB) Get e-AlertscloseSUBJECTS:Anatomy,Calcium phosphate,Implants Get e-Alerts
ICU4SAT: A General-Purpose Reconfigurable Instrument Control Unit Based on Open Source Components (2022)

As the number of earth observation missions in-creases, together with the number of images acquired by satel-lites, the need for optimizing onboard memory allocation and bandwidth to the ground is becoming more and more critical. Currently, large players in the space industry face this need by developing custom Instrument Control Units (ICUs), which can only be employed for the single mission they have been designed for. The unavailability of flexible, programmable, space-grade solutions ready to be integrated as building blocks keeps the costs of such units unaffordable for smaller missions and smaller industries, which do not have the resources needed to undertake custom development at a single system component level. Moreover, the development of this kind of component can increase the time to market of the system. The work presented in this paper aims at delivering an innovative fully programmable data handling and data processing System on a Chip (SoC) for modern ICUs onboard satellites, named ICU4SAT. We leveraged three highly innovative, open-source components: a RISC-V based processor as a command and control platform; the FPGA-GPU as hardware accelerator for computer vision and Artificial Intelligence algorithms; and the SpaceFibre/SpaceWire as high-speed communication modules to connect our system to the rest of the satellite. The three components are integrated into a single modular embedded architecture on a single chip, and more in particular on a space-grade FPGA. The result is a general-purpose ICU SoC, which can be potentially used to control and process data of any satellite image-based instrument. The ICU4SAT project aims to provide and fully programmable data handling and data processing modern ICU on board of satellites, also exploiting re-configurable FPGA technology. This will advance the state of the art from both the academic and industry point of view as it will: (i) Enable new mission concept by on-the-fly reconfigurability repurposing earth observation missions with no needs to launch new satellites as monitoring need change, even temporarily. (ii) Open new market opportunities for Small-Medium Enterprises since huge investments are not required to access this control unit solution.