gebhart/patrepeval huggingface dataset:
Multiple-objective cross-layer optimized content-adaptive scheduling for video streaming over 1xEV-DO (2005)

In video transmission over wireless cellular packet networks, service fairness, video quality and channel throughput should all be simultaneously guaranteed. In this regard, a key role is played by the scheduling algorithm, that - to achieve maximum performance should consider both physical and application layer information. At the application layer, we propose to consider the video perceptual importance, which depends on both the time-varying semantic relevance and the individual importance of each packet. In this paper, a novel multiple objective optimized (MOO) opportunistic multiple access scheme for slot assignment in a 1xEV-DO system is presented, and modifications to H.264 codec are also described. Here, the user that experiences the best compromise between the least buffer occupancy level, the best channel condition and the highest packet importance indicator is served at each time slot. Results show that this system outperforms the state-of-the-art techniques.
Structure and properties of x SnO–(100 – x) P2O5 glasses (2004)

x SnO–(100 – x ) P 2 O 5 glasses (0.30 ≤ x ≤ 0.75) were prepared under argon atmosphere. The Sn 2+ /Sn total ratio, determined by wet chemical analysis, varies from 90 to 99% depending on glass composition. Glass transition temperatures are very low, and no effect of Sn 4+ could be detected. Glass structure was characterised with 31 P and 119 Sn NMR. There is no evidence for a specific Q n site bonded to Sn 4+ , but taking into account the amount of Sn 4+ enabled to obtain Q n distribution close to calculated values for binary site distribution. 119 Sn NMR spectra were recorded in static conditions. Chemical shift anisotropy (CSA) of glasses were compared to crystalline reference compounds. Tin(II) local environment in glasses is close to a trigonal pyramid, and Sn 4+ NMR parameters are in accordance with a local environment similar to SnP 2 O 7 . .
Undecidable problems in malware analysis (2017)

Malware analysis is a challenging task in the theory as well as the practice of computer science. Many important problems in malware analysis have been shown to be undecidable. These problems include virus detection, detecting unpacking execution, matching malware samples against a set of given templates, and detecting trigger-based behavior. In this paper, we will give a review of the undecidability results in malware analysis and discuss what can be done in practice.
Interferon-α2b With Protease Inhibitor-Based Antiretroviral Therapy in Patients With AIDS-Associated Kaposi Sarcoma (2006)

We evaluated the safety and maximum tolerated dose of interferon (IFN)-alpha2b in combination with protease inhibitor-based highly active antiretroviral therapy (HAART) in a phase 1 study in 14 patients with AIDS-associated Kaposi sarcoma (KS). Planned IFN dose levels were 0, 1, 5, 10, and 15 million IU administered by daily subcutaneous injection. Dose-limiting toxicities were neutropenia and malaise. The maximum tolerated IFN dose was 5 million IU/d. The median CD4 count increased from 260 cells/muL at baseline to a maximum on-study value of 359 cells/muL. In 6 patients with paired baseline and on-study values, the median HIV RNA level decreased from 20,179 copies/mL to a minimum on-study value of 309 copies/mL. Of 13 patients whose KS response could be evaluated, 5 showed objective tumor regression. Responses occurred in HAART-experienced and HAART-naive subjects. Five patients, including 2 responders, 2 with stable KS, and 1 with progression, had serial measurements of Kaposi sarcoma herpesvirus (KSHV) load. None of these patients, irrespective of treatment arm or KS response, showed durable clearance of KSHV from plasma or peripheral blood mononuclear cells. This study establishes a safe dose of IFN that can be used with HAART and, potentially, with other inhibitors of KS in future clinical trials.
Fast Algorithm for Collision Detection between Deformable Objects (2009)

In this work, a novel method for solving minimum distance calculations between a pair of objects is presented. The method is based on the global optimization technique known as Genetic Algorithms, combined with a cut procedure that reduces the search space considerably, which accelerates convergence of the global stochastic search algorithm. Furthermore, the proposed algorithm may provide contact information in order to compute the efforts that must be applied if a collision occurs in case of deformable objects. Example with simple objects is presented.
Metal‐Controlled Selective [3 + 2] Cyclization Reactions of Alkenyl Fischer Carbene Complexes and Allenes. (2004)

Abstract For Abstract see ChemInform Abstract in Full Text.
Brachypodium as a Model for the Grasses: Today and the Future   (2011)

International audience
Emerging viral diseases : the example of bluetongue from Theiler to climate change (2012)

PowerPoint presentation and curriculum vitae of Prof. N. James MacLachlan. This Arnold Theiler Memorial Lecture was delivered on September 6, 2012 at the University of Pretoria, Faculty of Veterinary Medicine, Onderstepoort.
A Versatile Design Strategy for Thin Composite Planar Double-Sided High-Impedance Surfaces (2012)

A novel methodology is introduced for the design synthesis of thin planar realizations of volumetric high-impedance or artificial magnetic conducting surfaces (AMC). The design synthesis involves optimization of two different metallic frequency selective surface (FSS) type structures printed on each side of a thin dielectric substrate material. This technique eliminates the need for a complete metallic backplane common in conventional AMC designs, making use of the same dielectric substrate for two high-impedance surfaces; one on each side. Optimization of the FSS unit cell geometries is carried out with a robust genetic algorithm (GA) technique that is combined with a full-wave periodic finite element boundary integral (PFEBI) electromagnetic simulation code for fast and accurate optimization of desired AMC performance at a single frequency or over multiple frequency bands. Several examples of thin AMC ground planes are optimized for use in the X-band. Additional design examples that provide AMC behavior on one side and absorber behavior on the other are also provided. Lastly, an example illustrating the utility of the double-sided AMC separator structure is shown for a design targeting the standard Wi-Fi frequencies of 2.4 GHz and 5.2 GHz.
DNA replication of herpesviruses during the lytic phase of their life-cycles. (1990)

We have two goals in this review: the first is to relate what has been learned about DNA replication from the study primarily of herpes simplex virus type 1 (HSV-1); the second is to note briefly facets of this virus's mode of DNA replication that might serve as points of intervention for novel chemotherapeutic approaches in order to deal with primary and recurrent herpesvirus infections in man and animals. For the first goal we shall both summarize what has been learned and attempt to identify directions that may be pursued in order to further our understanding of DNA replication by herpesviruses. For the second goal we shall propose two schemes for the screening for drugs that might interfere uniquely with the DNA replication of this family of viruses.
Supplementary Figure 10 from Intrinsic Gene Expression Profiles of Gliomas Are a Better Predictor of Survival than Histology (2023)

Supplementary Figure 10 from Intrinsic Gene Expression Profiles of Gliomas Are a Better Predictor of Survival than Histology
Atomic Layer Deposition of TiN/Al<sub>2</sub>O<sub>3</sub>/TiN Nanolaminates for Capacitor Applications (2013)

Atomic layer deposition (ALD) of nanolaminates within porous alumina membranes is a highly promising path to produce high performance capacitors. Such systems have shown their feasibility and their very good properties. However there are still many improvements that should be achieved. TiN/Al 2 O 3 /TiN nanolaminates appear to be good candidates for such devices. In this study, the optimized parameters for Al 2 O 3 deposition were determined. The comparison of the chemical composition, crystal structure and morphology of TiN layers grown either by thermal or plasma-enhanced ALD was performed using various method such as TEM, SEM, XPS and electrical characterizations.
Gestion des occultations en réalité augmentée (2001)

Le concept de Réalité Augmentée vise à accroître la perception du monde réel en y ajoutant des éléments non perceptibles a priori par l'oeil humain. Plusieurs problèmes doivent être résolus pour obtenir une incrustation réaliste. Il faut tout d' abord pouvoir déterminer le point de vue adopté pour chaque prise de vue (alignement des caméras réelle et virtuelle) afin d'incruster l'objet de synthèse au bon endroit. Il faut ensuite tenir compte des interactions entre les éléments virtuels insérés et la scène réelle : les parties occultées de ces éléments doivent être déterminées, ainsi que les modifications de l'éclair age induit es par l'insertion de ces éléments. Cette thèse s'intéresse à la gestion des occultations, plus particulièrement en phase de post-production, qui demande des incrustations d'une grande qualité visuelle. Un algorithme de reconstruction tridimensionnelle permettrait a priori de résoudre notre problème. Nous mettons en évidence le manque de fiabilité des algorithmes existants, en particulier à proximité du bord des objets occultants, et nous expliquons pourquoi. Nous nous intéressons alors aux quelques travaux qui traitent plus spécifiquement des occultations. De cette étude ressort le fait qu'une intervention humaine reste nécessaire pour respecter nos impératifs de qualité. La méthode développée dans cette thèse met donc explicitement à contribution l'utilisateur, mais sa tâche reste intuitive et limitée, puisqu'il s'agit de détourer à l'aide d'un outil semi-automatique les objets occultants dans quelques images de la séquence. Cette méthode utilise les points de vue correspondant à chaque image. Nous décrivons donc comment nous calculons ces points de vue, mais également comment nous estimons l'erreur obtenue. Nous montrons ensuite comment la méthode de gestion des occultations tient compte de cette erreur, ce qui permet de l'utiliser dans des cas pratiques, où l'erreur sur les points de vue calculés peut être relativement importante. On peut alors obtenir efficacement la qualité visuelle requise, sur l'ensemble de la séquence, au prix d'une interactivité réduite. L'applicabilité de la méthode est démontrée sur de nombreuses séquences vidéo de différents types. Elle peut être utilisée pour déterminer les occultations par des objets rigides, immobiles ou non. Enfin, cette méthode dépasse le cadre de la gestion des occultations puisqu'elle peut être utilisée comme un outil de segmentation spatio-temporelle de séquences vidéo, débouchant alors sur de nombreuses applications en post-production : colorisation et suppression d 'objets, composition de séquences réelles et virtuelles.
Distribution of Reaction Products. V. Reactions Forming an Ionic Bond, M+XC (3 <scp>d</scp>) (1969)

In the previous paper (Part IV) a preliminary investigation was made of the electron-jump model for reactions M+XC[→M++(XC)−]→products, in which an alkali-metal atom M reacts with a halogen molecule (XC≡XY) or with a halide, to give alkali halide. The method used was the classical trajectory method in two dimensions (2d). In the present work some of these early calculations have been extended into 3d, and comparison has been made between theory and recent molecular-beam experiments. The 12 principal potential-energy hypersurfaces used in this 3d work comprised six which permitted charge migration and six which, though identical in other respects, did not permit charge migration. The groups of six exemplified the effects of separate variation in electron-jump distance, r1x, in the magnitude of the B·C repulsion in (BC)−, Ri, and in the total energy released, QC. All but the last of these variables had important effects on the product energy and angular distributions. It was found that with a proper choice of r1x and Ri, the crude electron-jump model used here was able to account very satisfactorily for the major features of the experimental findings. Sharp forward scattering of the molecular product was one of the features of reactions M+XY, both experimentally and theoretically. The mechanics of this forward scattering, according to the present work consist of an initial M+- -X− attraction, followed by charge migration to give M+Y−+X. The rejected atom is not, therefore, a “spectator,” but is subject to strong forces which enhance its translational energy. A qualitatively similar correlation between forward scattering and increased relative translational energy of the products has been observed experimentally by Birely and Herschbach. In addition, the calculations predict enhanced rotational excitation in the forward-scattered portion of the molecular product; experimental evidence is lacking on this point. The experiments show a striking change from rebound to forward scattering in going from M+XR (where R is an alkyl radical) to M+XY. This change in behavior stems, according to the present work, from the occurrence of charge migration coupled with markedly diminished product repulsion in the M+XY as compared with the M+XR family. A simple analytical model termed the DIPR (Direct Interaction with Product Repulsion) model was shown to account quantitatively for product energy and angular distributions in direct trajectories without secondary encounters. The model provides insight into the transition (on nonmigration surfaces) from backward to sideways to forward scattering as product repulsion is decreased, and shows the utility of the concept of a “stripping threshold energy.”
Simian Immunodeficiency Virus (2011)

An animal model using the pigtailed macaque co-infected with two SIV viruses recapitulates key clinical and pathological features of HIV infection of the peripheral and central nervous system (PNS, CNS). The pigtailed macaques in this model develop immunosuppression more rapidly than similarly co-infected rhesus macaques, and develop CNS lesions more frequently than either rhesus macaques or cynomologous monkeys when similarly coinfected. In this pigtail model, the majority of animals develop AIDS as well as CNS and PNS disease by 84 days post inoculation. Furthermore, this model recapitulates the acute, asymptomatic, and late stages of infection and disease in the CNS, making it possible to study stage-specific longitudinal viral and immunological changes and responses to therapies. This chapter discusses a range of important topics relevant to understanding SIV models of AIDS and NeuroAIDS in general, as well as this pigtail model in particular. These topics include areas related to normal immune responses, genetic susceptibilities, pathogenesis of HIV disease, and preclinical testing of neuroprotective agents.
Compressed SRv6 Network Programming (2020)

Segment Routing can be applied to the IPv6 data plane by leveraging a
new type of Routing Extension Header, called Segment Routing Header
(SRH). However, the overhead introduced by SRH may be a challenge for
existing hardware, which may influence on the forwarding performance
and the payload efficiency. This document defines a compressed SRv6
network programming mechanism in order to reduce the overhead of SRv6
by introducing the Compressed Segment Identifier (C-SID) and the
Compressed SRH (C-SRH). The C-SRH can be a new Routing Header or an
enhancement of SRH.
Slip Velocity in Downer Reactors: Drag Coefficient and the Influence of Operational Variables (2009)

Cluster formation in downer reactors is considered a most important factor influencing slip velocity between the flowing phases. This study investigates the formation of clusters using CREC-GS-Optiprobes. This probe is a nonintrusive device that records information from a well-defined optical measuring volume. This probe can provide accurate measurements tracking closely gas−solid flows in downer units. This study shows that cluster drag coefficients can be correlated as function of both Reynolds number and number of particles contained in agglomerates. This yields a close to linear relationship between cluster size and average slip velocity.
Medial meniscus posterior root repair reduces the extruded meniscus volume during knee flexion with favorable clinical outcome (2021)

Level IV.
PDCCH implementation based on 5G NR system and comparision with LTE PDCCH (2020)

The 5G NR system starts with Release 15 and includes Release 16. The NR system has added physical channels identical to LTE and physical channels for duplication in high-speed and high-frequency environments. In this paper, the characteristics of PDCCH physical channel in LTE and NR system are compared and the implementation of NR PDCCH is discussed.
Prognostic impact of urokinase-type plasminogen activator receptor (uPAR) in cytosols and pellet extracts derived from primary breast tumours (2001)

Using a previously developed enzyme-linked immunosorbent assay (ELISA), the levels of the receptor for urokinase-type plasminogen activator (uPAR) were determined in cytosols and corresponding membrane pellets derived from 878 primary breast tumours. The levels of uPAR in the pellet extracts were more than 3-fold higher than those measured in the cytosols (P< 0.001). Moreover, the uPAR levels in the two types of extracts were weakly, though significantly, correlated with each other (rS= 0.20, P< 0.001). In Cox univariate analysis, high cytosolic levels of uPAR were significantly associated with reduced overall survival (OS) and relapse-free survival (RFS). The levels of uPAR in pellet extracts appeared not to be related with patient survival. In multivariate analysis, elevated levels of uPAR measured in cytosols and pellet extracts were found to be independent predictors of poor OS, not RFS. The prediction of poor prognosis on the basis of high uPAR levels emphasizes its important role in plasmin-mediated degradation of extracellular matrix proteins during cancer invasion and metastasis.
Investigation of Regression Vector Structure of Human Skill Models (2009)

In this paper, we investigate the regression vector structure of human skill model. As an example, the human driving skill is described as a hinging hyperplane autoregressive exogenous (HHARX) model, which is able to deal with manipulation modes and their switches simultaneously. Simulation results illustrated that distances from the vehicle to the route side, velocities of vehicle at sampling times vt and vt-i are must be included in the regression vector of HHARX model while modeling human driving skill.
Supplementary Table 1 from Phase I Study of Decitabine-Mediated Gene Expression in Patients with Cancers Involving the Lungs, Esophagus, or Pleura (2023)

Supplementary Table 1 from Phase I Study of Decitabine-Mediated Gene Expression in Patients with Cancers Involving the Lungs, Esophagus, or Pleura
The Origins of Low Efficiency in Electrochemical De-Ionization Systems (2016)

Competing causes of efficiency loss in electrochemical and capacitive deionization systems were studied. Specifically, we explored voltage and pH related efficiency limitations of electrochemical deionization devices by comparing operational conditions in three different practical cell architectures. Static and slurry flow electrodes based on high surface area activated carbon active materials were implemented with and without ion exchange membranes. At applied biases as low as 1 V, we observe water electrolysis, pH drift, and a reduction in overall device efficiency. The impact of dissolved oxygen in the water stream was also examined and it was determined that water electrolysis products can skew common techniques for measuring conductivity and assessing desalination performance regardless of the amount of oxygen present. Additionally, the presence of ion selective membranes impacts the retention of pH-shifting species and can improve voltage stability and performance, while slurry electrodes exhibit higher ion removal efficiency than their static equivalents.
Direct Thrombin Inhibitors in Acute Coronary Syndromes (2009)

The acute coronary syndromes (ACS) represent a continuum of athereothrombotic diseases that result from near instantaneous platelet activation and the initiation of the coagulation cascade most often following plaque erosion/rupture. Due to the central role of thrombin in clot formation, many therapies have aimed at inhibiting the action of thrombin to slow or reverse the coagulation cascade and to minimize the morbidity of ACS. While unfractionated heparin has been the stalwart agent for the management of ACS, several unfavorable characteristics such as the inability to inhibit clot-bound thrombin and a vulnerability to circulating inhibitors have prompted the search for alternative agents. Direct thrombin inhibitors (DTIs) were developed in an effort to effectively block the prothrombotic effects of thrombin without the associated increase in hemorrhagic events seen with the use of heparin. Early trials evaluating the DTI hirudin for management of unstable angina (UA) and non-ST-elevation myocardial infarction (NSTEMI) were largely disappointing. More recent data has demonstrated significantly lower bleeding rates with a similar effect on ischemic endpoints with the use of the DTI, bivalirudin, across the spectrum of ACS. As a result, the use of bivalirudin for most patients presenting with UA, NSTEMI, or STEMI is increasing. In this chapter, the data regarding the use of DTI in ACS will be presented and suggestions for their use in specific clinical scenarios will be given.
Data from &lt;i&gt;MYC&lt;/i&gt;-Driven Neuroblastomas Are Addicted to a Telomerase-Independent Function of Dyskerin (2023)

&lt;div&gt;Abstract&lt;p&gt;The RNA-binding protein dyskerin, encoded by the &lt;i&gt;DKC1&lt;/i&gt; gene, functions as a core component of the telomerase holoenzyme as well as ribonuclear protein complexes involved in RNA processing and ribosome biogenesis. The diverse roles of dyskerin across many facets of RNA biology implicate its potential contribution to malignancy. In this study, we examined the expression and function of dyskerin in neuroblastoma. We show that &lt;i&gt;DKC1&lt;/i&gt; mRNA levels were elevated relative to normal cells across a panel of 15 neuroblastoma cell lines, where both N-Myc and c-Myc directly targeted the &lt;i&gt;DKC1&lt;/i&gt; promoter. Upregulation of &lt;i&gt;MYCN&lt;/i&gt; was shown to dramatically increase &lt;i&gt;DKC1&lt;/i&gt; expression. In two independent neuroblastoma patient cohorts, high &lt;i&gt;DKC1&lt;/i&gt; expression correlated strongly with poor event-free and overall survival (&lt;i&gt;P&lt;/i&gt; &lt; 0.0001), independently of established prognostic factors. RNAi-mediated depletion of dyskerin inhibited neuroblastoma cell proliferation, including cells immortalized via the telomerase-independent ALT mechanism. Furthermore, dyskerin attenuation impaired anchorage-independent proliferation and tumor growth. Overexpression of the telomerase RNA component, hTR, demonstrated that this proliferative impairment was not a consequence of telomerase suppression. Instead, ribosomal stress, evidenced by depletion of small nucleolar RNAs and nuclear dispersal of ribosomal proteins, was the likely cause of the proliferative impairment in dyskerin-depleted cells. Accordingly, dyskerin suppression caused p53-dependent G&lt;sub&gt;1&lt;/sub&gt; cell-cycle arrest in p53 wild-type cells, and a p53-independent pathway impaired proliferation in cells with p53 dysfunction. Together, our findings highlight dyskerin as a new therapeutic target in neuroblastoma with crucial telomerase-independent functions and broader implications for the spectrum of malignancies driven by &lt;i&gt;MYC&lt;/i&gt; family oncogenes. &lt;i&gt;Cancer Res; 76(12); 3604–17. ©2016 AACR&lt;/i&gt;.&lt;/p&gt;&lt;/div&gt;