gebhart/patrepeval huggingface dataset:
A Portable Spectrophotometer-Based Breathalyzer for Point-of-Care Testing of Diabetic Patients (2013)

Diabetes Mellitus is a metabolic disorder characterized by the lack of sufficient insulin. This disease has become a national epidemic in the United States, and therapy non-adherence has become one of the largest precursors leading to diabetic sequelae such as diabetic ketoacidosis. A potential source of patient therapy negligence is the discomfort associated with the finger prick method of glucose monitoring. As a result, a less invasive method to monitor diabetes is sought. This paper describes a portable breathalyzer that is being developed to monitor acetone in the breath of a diabetic patient. The proposed design aims to eliminate the finger prick through a simplified approach for monitoring acetone levels in correlation to elevated glucose levels, thus determining the onset of diabetic ketoacidosis.
Development of an automated fuzing station for the future armored resupply vehicle (1995)

The US Army is developing the Advanced Field Artillery System (SGSD), a next generation armored howitzer. The Future Armored Resupply Vehicle (FARV) will be its companion ammunition resupply vehicle. The FARV with automate the supply of ammunition and fuel to the AFAS which will increase capabilities over the current system. One of the functions being considered for automation is ammunition processing. Oak Ridge National Laboratory is developing equipment to demonstrate automated ammunition processing. One of the key operations to be automated is fuzing. The projectiles are initially unfuzed, and a fuze must be inserted and threaded into the projectile as part of the processing. A constraint on the design solution is that the ammunition cannot be modified to simplify automation. The problem was analyzed to determine the alignment requirements. Using the results of the analysis, ORNL designed, built, and tested a test stand to verify the selected design solution.
Reproducing color images using custom inks (1998)

We investigate the general problem of reproducing color images on an offset press using custom inks in any combination and number. While this problem has been explored previously for the case of two inks, there are a number of new mathematical and algorithmic challenges that arise as the number of inks increases. These challenges include more complex gamut mapping strategies, more efficient ink selection strategies, and fast and numerically accurate methods for computing ink separations in situations that may be either over-or under-constrained. In addition, the demands of high-quality color printing require an accurate physical model of the colors that result from overprinting multiple inks using halftoning, including the effects of trapping, dot gain, and the interreflection of light between ink layers. In this paper, we explore these issues related to printing with multiple custom inks, and address them with new algorithms and physical models. Finally, we present some printed examples demonstrating the promise of our methods.
Metabolic studies reveal that ruminal microbes of adult steers do not degrade rumen-protected or unprotected L-citrulline (2019)

In vitro and in vivo experiments were conducted to determine the metabolism of rumen-protected or unprotected l-citrulline (Cit) plus l-glutamine (Gln) by ruminal microbes. In the in vitro experiment, whole ruminal fluid (3 mL, containing microorganisms) from steers was incubated at 37 ºC with 5 mM Cit plus 6 mM Gln (in a rumen-protected or unprotected form) for 0, 0.5, 2, or 4 h after which times 50 µL samples were collected for AA and ammonia analyses. In the in vivo experiment, at 0.5 h before and 0, 0.5, 1, 2, 4, and 6 h after cannulated adult steers consumed 0.56 kg dried-distillers' grain mixed with 70 g Cit plus 70 g Gln (in a rumen-protected or unprotected form), samples of ruminal fluid and jugular venous blood were obtained for AA analyses. Results from both in vitro and in vivo experiments demonstrated extensive hydrolysis of rumen-unprotected Gln into glutamate, but little degradation of the rumen-protected Gln or rumen-protected and unprotected Cit by ruminal microbes. Concentrations of Cit and arginine in the plasma of steers consuming rumen-protected or unprotected AA increased at 1 and 2 h after the meal, respectively, when compared with values at 0 h. Collectively, these novel findings indicate that ruminal microbes of adult steers do not degrade extracellular Cit in a rumen-protected or unprotected form. Our results refute the view that all dietary AAs are extensively catabolized by ruminal microorganisms and also have important implications for dietary supplementation with Cit to ruminants to enhance the concentration of arginine in their plasma and their productivity.
Visual Diver Face Recognition for Underwater Human-Robot Interaction (2020)

This paper presents a deep-learned facial recognition method for underwater robots to identify scuba divers. Specifically, the proposed method is able to recognize divers underwater with faces heavily obscured by scuba masks and breathing apparatus. Our contribution in this research is towards robust facial identification of individuals under significant occlusion of facial features and image degradation from underwater optical distortions. With the ability to correctly recognize divers, autonomous underwater vehicles (AUV) will be able to engage in collaborative tasks with the correct person in human-robot teams and ensure that instructions are accepted from only those authorized to command the robots. We demonstrate that our proposed framework is able to learn discriminative features from real-world diver faces through different data augmentation and generation techniques. Experimental evaluations show that this framework achieves a 3-fold increase in prediction accuracy compared to the state-of-the-art (SOTA) algorithms and is well-suited for embedded inference on robotic platforms.
EEG source localization analysis in epileptic children during a visual working-memory task (2020)

We localize the sources of brain activity of children with epilepsy based on EEG recordings acquired during a visual discrimination working memory task. For the numerical solution of the inverse problem, with the aid of age-specific MRI scans processed from a publicly available database, we use and compare three regularization numerical methods, namely the standarized Low Resolution Electromagnetic Tomography (sLORETA), the weighted Minimum Norm Estimation (wMNE) and the dynamic Statistical Parametric Mapping (dSPM). We show that all three methods provide the same spatio-temporal patterns of differences between epileptic and control children. In particular, our analysis reveals statistically significant differences between the two groups in regions of the Parietal Cortex indicating that these may serve as "biomarkers" for diagnostic purposes and ultimately localized treatment.
Low-Loss Materials for Josephson Qubits (2014)

Abstract : I review progress at UCSB on understanding the physics of decoherence in superconducting qubits. Although many decoherence mechanisms were studied and fixed in the last 5 years, the most important ones are two-level state defects in amorphous dielectrics, nonequilibrium quasiparticles generated from stray infrared light, and radiation to slotline modes. With improved design, the performance of integrated circuit transmons using the Xmon design are now close to world record performance: these devices have the advantage of retaining coherence when scaled up to 9 qubits.
A National Survey of Skin Infections, Care Behaviors and MRSA Knowledge in the United States (2014)

A nationally representative sample of approximately 2000 individuals was surveyed to assess SSTI infections over their lifetime and then prospectively over six-months. Knowledge of MRSA, future likelihood to self-treat a SSTI and self-care behaviors was also queried. Chi square tests, linear and multinomial regression were used for analysis. About 50% of those with a reported history of a SSTI typical of MRSA had sought medical treatment. MRSA knowledge was low: 28% of respondents could describe MRSA. Use of protective self-care behaviors that may reduce transmission, such as covering a lesion, differed with knowledge of MRSA and socio-demographics. Those reporting a history of a MRSA-like SSTI were more likely to respond that they would self-treat than those without such a history (OR 2.05 95% CI 1.40, 3.01; p<0.001). Since half of respondents reported not seeking care for past lesions, incidence determined from clinical encounters would greatly underestimate true incidence. MRSA knowledge was not associated with seeking medical care, but was associated with self-care practices that may decrease transmission.
Hoe zegt u ? Beter spraakverstaan met binaurale hoorapparten en akoestische sensornetwerken (2011)

status: Published
Effects of a Highly Portable Noninvasive Open Ventilation System on Activities of Daily Living in Patients with COPD (2014)

<b>Background:</b> For patients with chronic obstructive pulmonary disease (COPD), an increase in exercise tolerance and ability to perform activities of daily living (ADLs) can mean an improved quality of life with fewer exacerbations and lower health care expenses. We evaluated a wearable, noninvasive open ventilation (NIOV) system designed to enhance exercise capacity and increase mobility. <b>Methods:</b> Patients with stable, oxygen-dependent COPD were recruited for this prospective, open-label, crossover study. Inclusion criteria included supplemental oxygen use, elevated dyspnea score, and the ability to perform ADLs. Patients performed a selected ADL for as long as tolerable while using standard oxygen therapy. Following a rest period, the same ADL was repeated using the NIOV system. ADL endurance time, oxyhemoglobin saturation measured by pulse oximeter ( SpO<sub>2</sub>), dyspnea, fatigue, and discomfort scores were recorded. <b>Results:</b> Thirty patients were enrolled and 29 patients completed the study. Mean ADL endurance increased by 85% (13.4 vs. 7.2 min) using NIOV compared with oxygen therapy (p<0.0001). Mean SpO<sub>2</sub> was significantly higher during ADLs using NIOV versus oxygen therapy (p<0.0001). Median dyspnea, fatigue, and discomfort scores were significantly lower using NIOV during ADLs compared to oxygen therapy (p<0.01). No device-related adverse events were observed. <b>Conclusions:</b> This study demonstrated that a novel, portable noninvasive open ventilation system can improve ADL performance in the home setting. Compared to standard oxygen therapy, the NIOV system provided statistically and clinically significant increases in ADL endurance time and oxygenation, while decreasing dyspnea, fatigue, and discomfort. The NIOV system appears to offer a practical option for increasing activity and exercise tolerance in oxygen-dependent patients with COPD.
Incidentally discovered distant cutaneous metastasis of sacral chordoma: a case with variation in S100 protein expression (compared to the primary tumor) and review of the literature (2012)

Chordomas represent rare malignant primary bone tumors most often occurring in the sacral area. These tumors uncommonly involve the skin and often follow a progressive course with multiple recurrences, metastases and eventual death. Reports of cutaneous metastases from chordoma are very rare. The immunohistochemical staining characteristics of these cutaneous metastases with comparison to the primary tumors are similarly rarely addressed in the literature. We report a rare case of incidentally discovered, small, solitary distant cutaneous metastasis of sacral chordoma that developed on the right upper back of a 44-year-old man with a history of multiple completely excised melanomas who had also been previously diagnosed with chordoma involving the sacrum 12 years earlier. We describe its pathologic features with comparison to the primary tumor and briefly review the literature. Immunohistochemically, the cutaneous metastasis and primary tumor both stained positively for pancytokeratin and vimentin, as expected. However, the cutaneous metastasis unexpectedly lacked S100 protein expression, whereas the primary tumor was S100 positive. This phenomenon has only been documented in one other case report. We demonstrate that late, incidentally discovered cutaneous metastasis with unexpected immunohistochemical staining features rarely occur and can present a diagnostic challenge.
Progressive Supranuclear Palsy Syndrome and Semantic Dementia in Neuropathologically Proven Lewy Body Disease: A Report of Two Cases (2015)

The impact of neuropathological lesions on the clinical symptoms and progression of Lewy body disease (LBD) remains unclear. To address this issue, we describe two illustrative cases of autopsy-proven LBD that presented atypical phenotypes of progressive supranuclear palsy syndrome and semantic dementia. Postmortem examination revealed diffuse LBD with massive brainstem involvement in case 1, whereas Lewy bodies predominated in the amygdala and neocortex in case 2. Alzheimer's disease pathology was present in both cases, and TDP-43 inclusions were noted in case 2. These cases illustrate two contrasted clinical presentations and highlight the heterogeneity within the underlying proteinopathies of neurodegenerative diseases.
FPGA Implementation of Reconfigurable CORDIC Algorithm and a Memristive Chaotic System With Transcendental Nonlinearities (2022)

Coordinate Rotation Digital Computer (CORDIC) is a robust iterative algorithm that computes many transcendental mathematical functions. This paper proposes a reconfigurable CORDIC hardware design and FPGA realization that includes all possible configurations of the CORDIC algorithm. The proposed architecture is introduced in two approaches: multiplier-less and single multiplier approaches, each with its advantages. Compared to recent related works, the proposed implementation overpasses them in the included number of configurations. Additionally, it demonstrates efficient hardware utilization and suitability for potential applications. Furthermore, the proposed design is applied to a memristive chaotic system with different transcendental functions computed using the proposed reconfigurable block. The memristive system design is realized on the Artix-7 FPGA board, yielding throughputs of 0.4483 and 0.3972 Gbit/s for the two approaches of reconfigurable CORDIC.
Advanced thermal tester for accurate measurement of internal thermal resistance of high power electronic modules (2001)

A thermal tester has been developed for the accurate measurement of the internal thermal resistance of high-power electronic modules. The tester is designed for the simultaneous measurement of 20 electronic modules each dissipating in excess of 200 W. The heat dissipated is transmitted to the ambient by water-cooled cold plates dedicated to each test site. The tester system layout, mounting assembly, hydraulic design, cold-plate spreader design and data acquisition instrumentation are described. Sample measurements and the associated uncertainty are also discussed. The sample results are validated by comparison with thermal modeling.
ChemInform Abstract: Formation of Medium‐Ring Diolides via Intramolecular Diels‐Alder Reactions of Dicarboxylic Ester‐Tethered Trienes. (1996)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Enhanced Active Targeting via Cooperative Binding of Ligands on Liposomes to Target Receptors (2013)

To achieve effective active targeting in a drug delivery system, we previously developed dual-targeting (DT) liposomes decorated with both vascular endothelial growth factor receptor-1 (VEGFR-1)-targeted APRPG and CD13-targeted GNGRG peptide ligands for tumor neovessels, and observed the enhanced suppression of tumor growth in Colon26 NL-17 tumor-bearing mice by the treatment with the DT liposomes encapsulating doxorubicin. In this present study, we examined the binding characteristics of DT liposomes having a different couple of ligands, namely, APRPG and integrin αvβ3-targeted GRGDS peptides. These DT liposomes synergistically associated to stimulated human umbilical vein endothelial cells compared with single-targeting (ST) liposomes decorated with APRPG or GRGDS. The results of a surface plasmon resonance assay showed that ST liposomes modified with APRPG or GRGDS peptide selectively bound to immobilized VEGFR-1 or integrin αvβ3, respectively. DT liposomes showed a higher affinity for a mixture of VEGFR-1 and integrin αvβ3 compared with ST liposomes, suggesting the cooperative binding of these 2 kinds of ligand on the liposomal surface. In a biodistribution assay, the DT liposomes accumulated to a significantly greater extent in the tumors of Colon26 NL-17 tumor-bearing mice compared with other liposomes. Moreover, the intratumoral distribution of the liposomes examined by confocal microscopy suggested that the DT liposomes targeted not only angiogenic endothelial cells but also tumor cells due to GRGDS-decoration. These findings suggest that "dual-targeting" augmented the affinity of the liposomes for the target cells and would thus be useful for active-targeting drug delivery for cancer treatment.
Performance evaluation of a thiopurine methyltransferase (TPMT) enzyme activity assay by reversed-phase HPLC (2000)

Performance evaluation of a thiopurine methyltransferase (TPMT) enzyme activity assay by reversed-phase HPLC
Design of a human-skill based PID controller using CMACs (2008)

Skilled workers decrease in these years. Then it is a problem that skilled techniques and know-how of specific work are not taken over to next generations. Therefore, a controller which is based on a human-skill is needed to design. On the other hand, in recent year, various neural networks (NNs) have been proposed. These technologies of the NNs enable us to deal with the nonlinear systems, and they play an important role in the field of control engineering. Furthermore, a cerebellar model articulation controller (CMAC) has been proposed as one of artificial NNs. The CMAC is highly abstracted mathematically, considering the cerebellar as a controller for the body motion system. The CMAC has the advantage for the short learning time compared with the conventional NNs. In this paper, a design of human-skill based PID controller using CMACs is proposed. According to the proposed method, PID gains are tuned by some CAMCs which have learned human-skill. Furthermore, the experiment in order to illustrate the proposed scheme was performed by using one of pilot-scaled helicopter control models.
A Multidimensional Scaling Analysis of Surface Perceptual Parameters on Scratch and Mar Visibility Resistance in Polymers (2017)

&lt;div class="section abstract"&gt;&lt;div class="htmlview paragraph"&gt;Brightness, transparency, and color impact critically the aesthetics of polymeric surfaces. They can significantly change the perception of common damages such as scratch and mar. Particularly, subtle mar damage is more dependent on surface perceptual properties. In this study, we investigate the impact of these attributes on scratch and mar visibility resistance of commercialized polymeric model systems frequently used in automotive industry. Twenty subjects were involved in a psychophysical test based on pairwise comparison, and results were treated using multidimensional scaling (MDS) analysis. A tied ordinal weighted Euclidian MDS model was used to visualize the relational structures of mar perception space. Results show that scratch visibility resistance tends to decrease with dark, more transparent, and green surfaces. Mar perception was reasonably conceptualized by a two-dimensional MDS space. MDS results show that Brightness, transparency and color have a decreasing level of impact on mar perception. Mar visibility resistance decreased with dark, less transparent, and green stimuli. However, transparency effect is still dependent on the sample background. To the best of our knowledge, this is the first MDS study applied to the analysis of mar perception on polymeric surfaces, or any surface damage perception in general. The presented MDS-based model can be utilized to study the effect of other attributes on surface perception. This approach offers a new avenue for the assessment of scratch and mar perception and the development of polymeric materials with better visibility resistance.&lt;/div&gt;&lt;/div&gt;
Network cost impact of solutions for mitigating optical impairments: comparison of methods, techniques, and practical deployments constraints (2006)

Based on the simulations of realistic network conditions, this paper analyzes the network-cost dependence of the following parameters: the reach, the presence of optical add-drop multiplexers (OADMs) and branching nodes, and the chromatic dispersion. Trends and guidelines for the determination of the best match between system specifications and optimum network cost are proposed. The performance and cost impact of electrical and optical methods are critically analyzed.
A Comparative Assessment of Intraocular Pressure in Prolonged Steep Trendelenburg Position Versus Level Supine Position Intervention (2012)

Introduction This study was undertaken following an adverse event at a regional medical center in New England. The anesthesia team became concerned about ocular perfusion and peri-ophthalmic and intraocular pressure changes during laparoscopic abdominal surgery in the steep Trendelenburg position. The complication identified, postoperative visual loss (POVL) due to posterior ischemic
Palladium-Catalyzed Enyne Cycloisomerization Reaction in an Asymmetric Approach to the Picrotoxane Sesquiterpenes. 2. Second-Generation Total Syntheses of Corianin, Picrotoxinin, Picrotin, and Methyl Picrotoxate (1999)

An alternative, more efficient synthesis of the picrotoxane core by palladium-catalyzed cycloisomerization of an enyne requires the design of a new catalyst system based upon 1,3-bis(dibenzophospholyl)propane and 2-(diphenylphosphino)benzoic acid as ligands. Thus, unlike thermal processes which leave little opportunity to address failed reactions, the transition-metal-catalyzed reaction provides opportunities for catalyst modification to overcome limitations. In this way, a seven-step synthesis of the picrotoxane core from carvone emerges. The formation of the bislactone depends critically on the ring substitution pattern. A myriad of selective transannular cyclizations occur as a function of this substitution pattern. The bislactone serves as a pivotal intermediate to picrotoxinin, picrotin, and corianin. During the course of the manipulation of the oxidation pattern to create the correct bislactone, an intermediate generated also provides access to methyl picrotoxate. An improved sequence from the bislactone to corianin compared to the first generation evolvesin part derived from enhanced control of stereoselectivity in the functionalization of the double bond in the cyclohexenyl portion of the picrotoxane skeleton. Later in the sequence, a hydroxyl-directed chemoselective lactone reduction is employed using lithium triacetoxyborohydride. In the course of these studies, two reactions that involve substitution with retention of configuration occur in high yield as a result of the remarkable reactivity of this densely functionalized ring system.
ChemInform Abstract: REACTIONS OF ELECTRON DEFICIENT DIENES WITH (ACYLMETHYLENE)TRIPHENYLPHOSPHORANES: ONE‐POT‐THREE‐STEP‐REACTIONS (1981)

Abstract In einer Eintopf‐Dreistufensynthese (Michael‐Addition, intramolekulare Addition, Wittig‐Eliminierung) reagieren die Azaazulene (I) in der Schmelze mit den entsprechenden Phosphoranen (II) zu den Cyclohexadienen (III).