gebhart/patrepeval huggingface dataset:
Broadband All-Optical Wavelength Conversion Using a Gain Peak Wavelength-Shifted Semiconductor Optical Amplifier Integrated Distributed Feedback Laser Diode Structure (2003)

We have obtained all-optical wavelength conversion over the range of 60 nm, for the first time, using a gain peak wavelength-shifted semiconductor optical amplifier (SOA) integrated distributed feedback laser diode. The broadband a wavelength conversion is demonstrated using a 2.5 GHz pump signal. The response of a 10 GHz mode-locked pulse is also investigated.
Influence of dielectric passivation layer thickness on LeTID in multicrystalline silicon (2018)

Hydrogen released from surface passivation layers during high-temperature firing plays a crucial role in surface and bulk defect passivation, particularly in multicrystalline silicon solar cells. However, recent studies have identified hydrogen as a possible catalyst to activate recombination within silicon. This work demonstrates the varying rate and extent of LeTID observed in multicrystalline silicon solar wafers that occurs by modulating the thickness of plasma deposited SiN <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">x</sub> :H films. In this study, we show that thicker SiN <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">x</sub> :H layers cause a faster rate of degradation and a higher maximum normalized defect density. We interpret this result as important evidence for the role of hydrogen in inducing LeTID in multicrystalline silicon.
Inside Cover: Oxygen Activation at the Active Site of a Fungal Lytic Polysaccharide Monooxygenase (Angew. Chem. Int. Ed. 3/2017) (2016)

Oxidative cleavage of glycosidic bonds allows lytic polysaccharide monooxygenases (LPMOs) to break polysaccharide chains. This activity enhances the enzymatic hydrolysis of recalcitrant carbohydrate biomass, such as cellulose or chitin. In their Communication on page 767 ff., F. Meilleur and co-workers provide a structural description of molecular-oxygen activation by a fungal LPMO at the mononuclear copper active site as revealed by X-ray and neutron crystallography and DFT calculations. Credit: J. Hemman.
Spectroelectrochemical Reactivities of Novel Polyaniline Nanotube Pesticide Biosensors (2007)

Abstract Summary: The preparation and characterisation of electrosynthetic polyaniline nanomaterials doped with phenanthrene sulphonic acid (PSA) is being presented. The polymeric nanomaterials prepared include processable poly( o ‐methoxy aniline) (POMA) and poly( 2,5 ‐dimethoxy aniline) (PDMA). Spectroelectrochemical reactivities of the electroactive polymeric nanotube systems as well as the nanobiosensor systems were studied by SEM, FTIR, UV‐Vis and Subtractively Normalised Fourier Transformed Infrared Spectroscopy (SNIFTIRS) techniques. Furthermore, cyclic and differential pulse voltammetric studies of the nanomaterials were also performed using platinum or thiol‐modulated gold electrodes. The SEM studies confirmed the nanorod morphology of the polyanilines. The heterogeneous rate constant, k o , for the nanopolymeric material and the diffusion coefficient of electrons, D e , was calculated and found to be in agreement with values expected for electron hopping along conducting polymer chains. Organophosphate pesticide nanobiosensor devices were prepared by encapsulating acetylcholinesterase (AChE) in the nanopolymeric composite. The biosensor amperometric response to the organophosphate pesticide called diazinon and the carbamate pesticide called carbofuran were studied. The sensor responses to pesticides followed typical electrochemical Michaelis‐Menten kinetics.
Passive downdraught cooling for schools in India: a study on Iira International School in Baroda, Gujarat, India (2012)

Abstract This study focuses on the design integration of passive downdraught evaporative cooling (PDEC) in a school building in the hot and dry climate of Gujarat, India. It sets out the design process through which different options were evaluated and assessed, and demonstrates that the combination of PDEC with other ‘common sense’ design principles can potentially deliver thermal comfort in school classrooms for most of the year. This is the first time that the application of PDEC to this building type has been evaluated, and indicates significant potential for wider adoption in India. It is anticipated that following construction, post-occupancy evaluation will be undertaken to establish performance in practice. Keywords: Hot and dry climateIndia passive downdraught evaporative coolingschools Acknowledgements The Iira Foundation, based in Ahmedabad, India, is the client for the Iira International School project at Baroda, and Aditi and Mahesh Iyer are the architects. Notes
A Random Bag Preserving Product Operation (2009)

The author's current research programme is the development of a modular calculus for the average-cost of data structuring. This modular calculus provides a novel foundation for the analysis of algorithms. Its applicability to the analysis of algorithms has been demonstrated at the Center for Efficiency-Oriented Languages (CEOL) through the design of the novel programming language MOQA and the associated average-case analysis tool DISTRI-TRACK [M. Schellekens, D. Hickey and G. Bollella, ACETT, a Linearly-Compositional Programming Language for (semi-)automated Average-Case analysis, IEEE Real-Time Systems Symposium - Work In Progress Session, 2004; M. Boubekeur, D. Hickey, J. Mc Enery and M. Schellekens, A new Approach for Modular Average-Case Timing of Real-Time Java Programs, Accepted for publication in WSEAS Transactions on Computers, 2007; M. Boubekeur, D. Hickey, J. Mc Enery and M. Schellekens, Towards Modular Average-Case Timing in Real-Time Languages: An Application to Real-Time Java, Accepted for publication on the 6th WSEAS International Conference on APPLIED COMPUTER SCIENCE (ACS'06), Tenerife, December, 2006; M. Schellekens, A Modular Calculus for the Average Cost of Data Structuring, Springer book to appear, 250 pages, May 2008 (to appear), M. Schellekens, Compositional Average-Case Analysis, preprint, under review, 2006]. Modular computations of the average cost of data structuring are possible through the fundamental notion of random bag preservation. Random bag preserving operations enable the constructive tracking of the data and the distribution of the data states during a MOQA computation. This in turn enables the (semi-)automated derivation of the average cost of the operations. Two fundamental MOQA operations enable the creation and destruction of data structures: the MOQA product operation, which is the subject of this paper, and the MOQA delete operation, which forms the subject of [M. Schellekens, Compositional Average-Case Analysis, preprint, under review, 2006]. The introduction of the entire MOQA language is well beyond the scope of this paper and will be reported in a book [M. Schellekens, A Modular Calculus for the Average Cost of Data Structuring, Springer book to appear, 250 pages, May 2008 (to appear)]. The language has been implemented at CEOL and automated derivations of average-cost of data structuring are under way. Here we report on a (simplified) version of the fundamental notion of random bag preservation and demonstrate that the central MOQA product operation possesses this crucial property.
Non‐alcoholic steatohepatitis, but not simple steatosis, disturbs the functional homogeneity of the liver – a human galactose positron emission tomography study (2019)

In NASH, the regional metabolic liver function was lower and more heterogeneous than in both simple steatosis and healthy controls. Thus, NASH disturbs the normal homogeneous metabolic function of the liver.
Output Voltage Control of Resonant Boost Switched Capacitor Converter (2007)

Conventional switched capacitor converters have an inherent drawback that their efficiency is much decreased as the output current is increased. To solve this problem we presented a novel switched capacitor converter topology that uses a resonant operation instead of the forced charging and discharging operation. Its advantage over a conventional switched capacitor converter is a high efficiency even in a high output current region. In this paper, firstly, the operation analysis and the steady-state characteristics are analyzed for a double boost type switched capacitor converter with synchronous rectifiers under the condition that the switching frequency matches with the resonant frequency. Next, the steady-state characteristics are analyzed when using the output voltage control by changing the switching frequency.
&lt;title&gt;Analysis of the complex light field generated by a deflectable mirror array device&lt;/title&gt; (2006)

An exact analysis of the scalar coherent monochromatic light field produced by a deflectable mirror array device is presented. The three-dimensional light field is related to the tilt angles of the mirrors. The first Rayleigh-Sommerfeld diffraction formula is used to model the diffraction. The analysis is carried out based on the assumption that the mirrors can be tilted with continuously varying angles, so the field produced by a finite (discrete) set of possible tilt angles is included as a special case.
Geophysical surveying of the ancient walls of the town of Cagliari, Italy, by means of refraction and up‐hole seismic tomography techniques (2018)

Abstract The ancient walls of Santa Croce in the town of Cagliari (Sardinia, Italy), date back to the Middle Age and have had, until the nineteenth century, several interventions with superpositions and modifications. Beyond the historical and archaeological interest, the study of the structure of the ancient walls became necessary in view of building an underground car parking just at the base of the walls itself. With this purpose, in addition to classical archaeological surveys a geophysical non‐destructive survey with seismic techniques has been carried out, namely two refraction tomographies aimed at characterizing the rocks at the base of the walls, and four up‐hole tomographies across the walls itself. These geophysical surveys provide good geotechnical information on the foundation condition, the problematic feasibility of the underground parking and, along with the archaeological procedures, on the heterogeneous structure of the walls.
Holographic particle image velocimetry measurements of hairpin vortices in a subcritical air channel flow (2006)

A holographic particle image velocimetry (HPIV) system is employed to study the evolution of coherent structures artificially generated in a plane Poiseuille air flow. As a first step the hot-wire technique and two-dimensional flow visualization are used to determine the generation conditions and dimensions of the coherent structures, their shedding frequency, trajectory, and convection velocity. Then, the HPIV method is utilized to obtain the instantaneous topology of the hairpin vortex and its associated three-dimensional distribution of the two (streamwise and spanwise) velocity components as well as the corresponding wall-normal vorticity. Finally, the experimental data are compared with results of related experimental and numerical studies. The present experimental results support the view that the generation of hairpins under various base flow conditions is governed by a basic mechanism, the important common elements of which are the shear of the base flow and an initial disturbance having a sufficiently large amplitude.
Phase-Sensitive Fiber-Optic Parametric Amplifiers and their Applications (2013)

Some basics and recent progress in nonlinear fiber-based phase-sensitive parametric amplifiers is discussed. In addition, their potential use as in-line amplifiers, resulting in significant link performance improvement potential, is highlighted.
Data from Pilot Study of Vaccination with Recombinant CEA-MUC-1-TRICOM Poxviral-Based Vaccines in Patients with Metastatic Carcinoma (2023)

&lt;div&gt;Abstract&lt;p&gt;&lt;b&gt;Purpose:&lt;/b&gt; Poxviral vectors have a proven safety record and can be used to incorporate multiple transgenes. Prior clinical trials with poxviral vaccines have shown that immunologic tolerance to self-antigens can be broken. Carcinoembryonic antigen (CEA) and MUC-1 are overexpressed in a substantial proportion of common solid carcinomas. The primary end point of this study was vaccine safety, with immunologic and clinical responses as secondary end points.&lt;/p&gt;&lt;p&gt;&lt;b&gt;Experimental Design:&lt;/b&gt; We report here a pilot study of 25 patients treated with a poxviral vaccine regimen consisting of the genes for CEA and MUC-1, along with a triad of costimulatory molecules (TRICOM; composed of B7.1, intercellular adhesion molecule 1, and lymphocyte function–associated antigen 3) engineered into vaccinia (PANVAC-V) as a prime vaccination and into fowlpox (PANVAC-F) as a booster vaccination.&lt;/p&gt;&lt;p&gt;&lt;b&gt;Results:&lt;/b&gt; The vaccine was well tolerated. Apart from injection-site reaction, no grade ≥2 toxicity was seen in more than 2% of the cycles. Immune responses to MUC-1 and/or CEA were seen following vaccination in 9 of 16 patients tested. A patient with clear cell ovarian cancer and symptomatic ascites had a durable (18-month) clinical response radiographically and biochemically, and one breast cancer patient had a confirmed decrease of &gt;20% in the size of large liver metastasis.&lt;/p&gt;&lt;p&gt;&lt;b&gt;Conclusions:&lt;/b&gt; This vaccine strategy seems to be safe, is associated with both CD8 and CD4 immune responses, and has shown evidence of clinical activity. Further trials with this agent, either alone or in combination with immunopotentiating and other therapeutic agents, are warranted.&lt;/p&gt;&lt;/div&gt;
Causal Prediction Of Continuous-Valued Music Features. (2011)

[TODO] Add abstract here.
Pharmacologic maintenance of abstinence in patients with alcoholism: No efficacy of 5-hydroxytryptophan or levodopa (1992)

Pharmacologic enhancement of central nervous system serotonin and dopamine functions has been postulated to improve maintenance of abstinence in patients with alcoholism. To test this hypothesis, patients with alcoholism who completed a 42-day inpatient treatment program were randomized to be administered, in a double-blind fashion, either 5-hydroxytryptophan and carbidopa, levodopa and carbidopa, or placebo for 1 year. Eight of 31 patients who entered the analysis remained abstinent from alcohol for 1 year; however, there was no significant effect of the treatment condition on maintenance of abstinence. Baseline psychologic measures showed that patients who abstained from alcohol had more education and higher scores on memory function tests. Measures of cerebrospinal fluid obtained before the start of the study indicated that all patients who had higher concentrations of the dopamine metabolite homovanillic acid relapsed, suggesting that further research is needed to elucidate the role of dopamine in alcoholism.
<i>STAT3/PIAS3</i> Levels Serve as “Early Signature” Genes in the Development of High-Grade Serous Carcinoma from the Fallopian Tube (2018)

The initial molecular events that lead to malignant transformation of the fimbria of the fallopian tube (FT) through high-grade serous ovarian carcinoma (HGSC) remain poorly understood. In this study, we report that increased expression of signal transducer and activator of transcription 3 (<i>pSTAT3 Tyr705</i>) and suppression or loss of protein inhibitor of activated STAT3 (<i>PIAS3</i>) in FT likely drive HGSC. We evaluated human tissues-benign normal FT, tubal-peritoneal junction (TPJ), p53 signature FT tissue, tubal intraepithelial lesion in transition (TILT), serous tubal intraepithelial carcinoma (STIC) without ovarian cancer, and HGSC for expression of <i>STAT3/PIAS3</i> (compared with their known <i>TP53</i> signature) and their target proliferation genes. We observed constitutive activation of <i>STAT3</i> and low levels or loss of <i>PIAS3</i> in the TPJ, p53 signature, TILT, and STIC through advanced stage IV (HGSC) tissues. Elevated expression of <i>pSTAT3 Tyr705</i> and decreased levels of <i>PIAS3</i> appeared as early as TPJ and the trend continued until very advanced stage HGSC (compared with high <i>PIAS3</i> and low <i>pSTAT3</i> expression in normal benign FT). Exogenous expression of <i>STAT3</i> in FT cells mediated translocation of <i>pSTAT3</i> and <i>c-Myc</i> into the nucleus. <i>In vivo</i> experiments demonstrated that overexpression of <i>STAT3</i> in FT secretory epithelial cells promoted tumor progression and metastasis, mimicking the clinical disease observed in patients with HGSC. Thus, we conclude that the <i>STAT3</i> pathway plays a role in the development and progression of HGSC from its earliest premalignant states.<b>Significance:</b> Concomitant gain of pSTAT3 Tyr705 and loss of PIAS3 appear critical for initiation and development of high-grade serous carcinoma. <i>Cancer Res; 78(7); 1739-50. ©2018 AACR</i>.
Antiepileptic Drugs. 3rd edition (1990)

Book reviews adjuncts to neuroleptics in the treatment of schizophrenia.The authors-two of whom
Radiation-related genomic profile of papillary thyroid carcinoma after the Chernobyl accident (2021)

Radioactive iodine (131I)-exposed children in the region of Chernobyl (Ukraine) showed an increased incidence of papillary thyroid carcinoma (PTC) after the 1986 nuclear plant accident [1]. This so far the largest and most comprehensive study to characterize the genomic landscape of radiation induced PTC in a large number of tissues from the Chernobyl Tissue Bank originating from a precisely phenotyped cohort of 131I exposed patients. The findings reveal DNA damage as early driver of carcinogenesis and lack of a unique molecular signature for radiation induced PTC.
Global gene expression and chromatin accessibility of the peripheral nervous system in animal models of persistent pain (2021)

Our improved understanding of the changes in chromatin accessibility that occur in chronic pain states may identify regulatory genomic elements that play essential roles in modulating gene expression in the DRG.
Abstract 5582: Safety and Efficacy of Rivaroxaban in Prevention of Venous Thromboembolism in Patients Undergoing Elective Major Orthopedic Surgery: A Meta-Analysis of Randomized Controlled Trials (2009)

Background: Venous thromboembolism is a significant cause of morbidity and mortality after major orthopedic surgery. Recent clinical trials comparing enoxaparin with rivaroxaban, a novel oral factor Xa inhibitor for thromboprophylaxis were not adequately powered to detect differences in low frequency clinical outcomes. We evaluated the impact of rivaroxaban in prevention of deep venous thrombosis (DVT) and pulmonary embolism (PE) compared to enoxaparin in patients undergoing elective total knee replacement (TKR) or total hip replacement (THR). Methods: Eight randomized trials (n=13398 patients) comparing rivaroxaban (10 mg/day) with enoxaparin therapy were included. Summary odds ratios for DVT, PE, deaths, major bleeding and cardiovascular events were calculated using random-effects models. Results: Rivaroxaban therapy was associated with a significant reduction in DVT (Odds ratio [OR] 0.49, 95% CI 0.33 – 0.75, p = 0.001). There was no significant difference in the incidence of PE (OR 0.90, 95% CI 0.30 –2.77, p = 0.86), deaths (OR 0.66, 95% CI 0.27–1.65, p = 0.38) or cardiovascular events (OR 0.91, 95% CI 0.50 –1.65, p = 0.76) during follow up for rivaroxaban compared to enoxaparin in THR and TKR populations. Major bleeding (OR 1.56, 95% CI 0.86 –2.83, p = 0.15) was also not significantly different between the two regimens. Conclusion: Rivaroxaban as a fixed once daily anticoagulant may be a more effective agent compared to enoxaparin for thromboprophylaxis in patients undergoing major orthopedic surgery.
Differential Difference Amplifier based Parametric Measurement Unit with Digital Calibration (2018)

The proposed PMU with differential difference amplifier (DDA) promises stable operation, accuracy, and reduced power consumption by reducing the number of operational amplifier from five to one. In addition, digital calibration is applied to improve accuracy of forcing ability. The PMU works under various loads from 12.5 Omega to 50 k Omega In the forcing voltage mode, the PMU forces a voltage of 0 V to 3.5 V. In the forcing current mode, the PMU forces a current of 0.7 mu A to 19 mA. The PMU is fabricated using the Magnachip 0.18-mu m BCD technology. The total area of the PMU including the resistor bank is 2 mu m(2), and the active area is 0.2 mu m(2).
Tunable Doping and Characterization of Single-Wall Carbon Nanotube Macrosystems for Electrode Material Applications (2021)

We present an efficient method for easy tuning of optical and electrophysical parameters of macroscopic objects formed from single-wall carbon nanotubes (SWCNTs). We have developed a unique step-by-step doping procedure by filling the SWCNT inner channels with acceptors and donors in gaseous conditions. The main parameter that tailors the film properties is the dopant concentration in the SWCNT channels varied through the gaseous filling time. The ambient oxygen impact on the doping level has been measured and analyzed for all considered SWCNT objects. Our approach provides a predictable shift of Fermi level position in the range of 0.1–0.9 eV and the optical band gap edge value between 0.4 and 1.1 eV. The tuning method was applied to optimize the thermopower performance of SWCNT films. We have measured the maximum possible values of the power factor and thermoelectric coefficient and studied the stability of these parameters in the air for studied samples. On the basis of the revealed relation between thermopower and sheet resistance, we propose a general approach for characterization of conducting CNT macro-objects, which we call the “doping map” plotting. This empirical method allows to predict stable, maximum, or optimal values for the transport, thermopower, and optical characteristics of materials in the air. Our findings are prospective for prediction and tailoring of SWNT-containing materials properties used in such technological applications, as electrochemical, sensor, solar cell, or thermoelectric electrode materials.
Supplemental Tables: The influence of EPA and DHA on the transcriptional responses to high-fat feeding in skeletal muscle and liver (2019)

Supplemental tables included in the manuscript: "The influence of EPA and DHA on the transcriptional responses to high-fat feeding in skeletal muscle and liver" by Kunz H, Dasari S, and Lanza IR.
Nano-structured organic-metal interface for high efficiency organic solar cells (2011)

High bimolecular recombination has been identified as a performance limiting parameter in organic solar cells. To counter this issue, we introduce a structured-junction device architecture for efficient photogeneration and extraction leading to power conversion efficiencies in excess of 6%.
Molecular cloning and characterization of the xylose isomerase gene from a thermophilic Bacillus species. (1995)

The gene (xylA) encoding a thermostable xylose isomerase has been isolated and characterized from a thermophilic Bacillus species for the first time. The xylA open reading frame of 1323 bp encoded a protein containing 441 amino acids with a calculated molecular weight of 50,176. The amino acid sequence of this protein showed 76% homology to xylose isomerase isolated from Bacillus subtilis and contained all the important catalytic domains of the enzyme. The gene complemented the xyl-5 mutation and produced a functional enzyme constitutively in Escherichia coli. The crude cell-free extract of E. coli recombinants exhibited xylose isomerase activity over a wide range of temperatures from 60 to 100 degrees C with an optimal enzyme activity of 10.4 Units/mg protein at 85 degrees C. This optimal temperature was one of the highest reported so far for thermostable xylose isomerases. The recombinant enzyme was found to be a tetramer with each subunit having molecular weight of 50,000.