gebhart/patrepeval huggingface dataset:
Atom-Field QuantumState Manipulation andStorage (2005)

We present various schemes tomanipulate andstore quantumoptical fields into atomic ensembles andshowhowtorealize quantummemoryoperations, entangle atomic ensembles or teleport anatomic ensemble quantum state withhighefficiency. A major challenge inquantum information andcommunication lies intheability tomanipulate andstore quantum states ondemand. Quantum networks consisting ofatomic ensemble nodes connected bylight represent apromising, wayto achieve robust quantum communication. Because ofthelonglifetime oftheir ground state spin, atomic ensembles are goodcandidates tostore thequantum state ofoptical light fields. Wepropose ascheme toachieve quasi-perfect atom-field quantum state transfers inon-resonance Electromagnetically Induced Transparency (EIT) oroff-resonant Ramanconfigurations (11. Weshowthat dissipation isnegligible forsuch interactions, sothat thequantum states arepreserved during transfer operations. Wefirst showhowtomapabroadband squeezed vacuumontotheatomic ground state coherence ofaspin-polarized ensembles. Wefind theoptimal conditions forhighefficiency transfer andpresent amethod toreadout theatomic state inorder toperform aquantum memoryoperation (11. Wealso compare cavity andsingle passschemes; eventhough a cavity interaction turns outtobemoreefficient, single passinteraction should allow forverygoodquality transfer for realistic experimental parameters. We thenpropose toentangle twomacroscopic atomic ensembles using apairofEPR-correlated incident fields. Entanglement isalsoshowntobeconserved during on-resonant oroff-resonant interactions, andcanbestored fora longtimeintwospatially separated ensembles (2). Theatomic entanglement canthenbereadout intheoptical fields exiting thecavities.
Author response: Building the vertebrate codex using the gene breaking protein trap library (2020)

The human genome counts over 20,000 genes, which can be turned on and off to create the proteins required for most of life processes. Once produced, proteins need move to specific locations in the cell, where they are able to perform their jobs. Despite striking scientific advances, 90% of human genes are still under-studied; where the proteins they code for go, and what they do remains unknown. Zebrafish share many genes with humans, but they are much easier to manipulate genetically. Here, Ichino et al. used various methods in zebrafish to create a detailed ‘catalogue’ of previously poorly understood genes, focusing on where the proteins they coded for ended up and the biological processes they were involved with. First, a genetic tool called gene-breaking transposons (GBTs) was used to create over 1,200 strains of genetically altered fish in which a specific protein was both tagged with a luminescent marker and unable to perform its role. Further analysis of 204 of these strains revealed new insight into the role of each protein, with many having unexpected roles and localisations. For example, in one zebrafish strain, the affected gene was similar to a human gene which, when inactivated, causes severe muscle weakness. These fish swam abnormally slowly and also had muscle problems, suggesting that the GBT fish strains could ‘model’ the human disease. This work sheds new light on the role of many previously poorly understood genes. In the future, similar collections of GBT fish strains could help researchers to study both normal human biology and disease. They could especially be useful in cases where the genes responsible for certain conditions are still difficult to identify.
A mobile client platform for sensor networks (2008)

Presented is the design, hardware implementation and evaluation of a mobile computing platform that is well suited for use as an interface to wireless sensor networks.The device incorporates an 802.15.4 radio interface common in contemporary sensor network platforms, a color 320240 pixel low-power organic LED (OLED) graphical display, an input device, and computation resources.The system includes several sensors relevant to a mobile device in a sensor network -a digital compass, multiple temperature sensors, a humidity sensor, and a pressure sensor for altimeter or barometer applications.The system incorporates these facilities, along with a rechargeable 2000 mAh lithium-polymer battery, all within a form-factor of 2.1"4"0.5".The platform contains many hardware facilities to support current and future research directions in wireless sensor networks and their interactions with mobile computing systems, including a low-power signal strength monitoring circuit independent of the system's main radio, support for dynamic operating voltage setting, power gating of peripherals, and built-in power monitoring circuits for power consumption introspection.
Supplementary Figure S4 from Murine Oviductal High-Grade Serous Carcinomas Mirror the Genomic Alterations, Gene Expression Profiles, and Immune Microenvironment of Their Human Counterparts (2023)

&lt;p&gt;Figure S4 shows correlation of RNA expression in human and mouse HGSCs using a subset of genes&lt;/p&gt;
Cyclodextrin Complexes of Polymers Bearing Adamantyl Groups: Host–Guest Interactions and the Effect of Spacers on Water Solubility (2007)

Thermoresponsive polymer inclusion complexes were prepared by radical polymerization in water of acrylamides bearing adamantyl groups by the use of randomly methylated β-cyclodextrin (Me-β-CD). Aqueous solutions of the resulting polymer complexes show a temperature-dependent transparency arising from a reversible dissociation above a critical temperature. The rate of the process strongly depends on the distance between the adamantyl groups and the polymer main chain.
Maturation of Purkinje cell firing properties relies on neurogenesis of excitatory neurons (2021)

Preterm infants that suffer cerebellar insults often develop motor disorders and cognitive difficulty. Excitatory granule cells, the most numerous neuron type in the brain, are especially vulnerable and likely instigate disease by impairing the function of their targets, the Purkinje cells. Here, we use regional genetic manipulations and in vivo electrophysiology to test whether excitatory neurons establish the firing properties of Purkinje cells during postnatal mouse development. We generated mutant mice that lack the majority of excitatory cerebellar neurons and tracked the structural and functional consequences on Purkinje cells. We reveal that Purkinje cells fail to acquire their typical morphology and connectivity, and that the concomitant transformation of Purkinje cell firing activity does not occur either. We also show that our mutant pups have impaired motor behaviors and vocal skills. These data argue that excitatory cerebellar neurons define the maturation time-window for postnatal Purkinje cell functions and refine cerebellar-dependent behaviors.
Native cellulose nanofibers: From biomimetic nanocomposites to functionalized gel spun fibers and functional aerogels (2012)

Native cellulose nanofibers : From biomimetic nanocomposites to functionalized gel spun fibers and functional aerogels
Knowledge encapsulation for focused search from pervasive devices (2001)

Article Knowledge encapsulation for focused search from pervasive devices Share on Authors: Yariv Aridor IBM Research Lab in Haifa, Matam, Haifa 31905, Israel IBM Research Lab in Haifa, Matam, Haifa 31905, IsraelView Profile , David Carmel IBM Research Lab in Haifa, Matam, Haifa 31905, Israel IBM Research Lab in Haifa, Matam, Haifa 31905, IsraelView Profile , Yoëlle S. Maarek IBM Research Lab in Haifa, Matam, Haifa 31905, Israel IBM Research Lab in Haifa, Matam, Haifa 31905, IsraelView Profile , Aya Soffer IBM Research Lab in Haifa, Matam, Haifa 31905, Israel IBM Research Lab in Haifa, Matam, Haifa 31905, IsraelView Profile , Ronny Lempel Department of Computer Science, Technion, Haifa 32000, Israel Department of Computer Science, Technion, Haifa 32000, IsraelView Profile Authors Info & Claims WWW '01: Proceedings of the 10th international conference on World Wide WebMay 2001 Pages 754–764https://doi.org/10.1145/371920.372195Online:01 April 2001Publication History 8citation368DownloadsMetricsTotal Citations8Total Downloads368Last 12 Months2Last 6 weeks0 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteGet Access
A transfer matrix formulation of an electromechanical Helmholtz resonator (2005)

An electromechanical Helmholtz resonator (EMHR) employing a compliant piezoelectric composite backplate is under development at the University of Florida. The acoustic impedance of the EMHR is made tunable and additional degrees of freedom (DOF) are added by coupling the piezoelectric composite diaphragm to a passive electrical shunt network. A formula of the transfer matrix is subsequently derived to predict the behavior of the EMHR. The theoretical aspects of electromechanical tuning are then reviewed and proof-of-concept experimental data are presented for a variety of resistive, capacitive, and inductive shunts in a normal-incidence plane wave tube (PWT). For resistive and capacitive shunt circuits, the resonator is shown to be a two DOF system, and short-circuit and open-circuit loads define the limits of the tuning range. There is approximately a 9% tuning limit under these conditions for the resonator configuration studied. An inductive shunt load results in a three DOF system with an enhanced tuning range of over 20% that is not restricted by the short-circuit and open-circuit limits.
Early onset of effect following galcanezumab treatment in patients with previous preventive medication failures (2021)

ClinicalTrials.gov , NCT03559257 . Registered 18 June 2018.
Convergence of Dip-Pen Nanolithography and acoustic biosensors towards a rapid-analysis multi-sample microsystem (2012)

The present work demonstrates for the first time patterning of a ready-to-use biosensor with several different biomolecules using Dip-Pen Nanolithography (DPN) for the development of a procedure towards more rapid and efficient multi-sample detection. The biosensor platform used is based on a Surface Acoustic Wave (SAW) device integrated with a parallel-channel microfluidic module, termed as "microfluidics-on-SAW" ("μF-on-SAW"), for reproducible multi-sample analysis. Lipids with different functionalized head groups were patterned at distinct, microfluidic-formed rectangular domains with sharp edges all located on the same sensor surface; pattern quality was verified using a fluorescent microscope. The functionality of the head groups, the efficiency of the patterning method, and the suitability of DPN for the surface modification of the acoustic device were subsequently examined through acoustic experiments. The μF-on-SAW configuration was used to detect specific binding between the pre-patterned functionalized lipids with their corresponding biomolecules. The achievement of an improved sensitivity (5-fold compared to previous acoustic configurations) and reduced preparation time by at least 2 h clearly indicates the suitability of DPN as a direct patterning method for ready-to-use acoustic sensor devices like the μF-on-SAW towards integrated, rapid-analysis, multi-sample biosensing microsystem development.
Estrogen Regulation of Prothymosin Alpha (2003)

Abstract : Prothymosin a (PTa) is a small highly acidic protein found in the nuclei of virtually all mammalian tissues. Its high conservation in mammals and wide tissue distribution suggest an essential biological role. While the exact mechanism of action of PTa remains elusive, the one constant has been its relationship with the proliferative state of the cell and its requirement for cellular growth and survival. Recently PTa was found to promote transcriptional activity by sequestering the anticoactivator, REA from the Estrogen Receptor (ER) complex. We now report that Estradiol (E2) upregulates PTa mRNA and protein expression. Further studies indicate that ERa regulates PTa gene transcriptional activity. We have also delimited the region of PTa gene promoter involved in ERa mediated transcriptional regulation and identified a novel ERa-binding element. Increased intracellular PTa expression in the presence of estrogen is accompanied by increased nuclear/decreased cytoplasmic localization. Increased nuclear expression of PTa in correlated with increased proliferation as measured by expression. of Ki67 nuclear antigen. Conversely, inhibition of nuclear PTa expression in breast cancer cells using antisense methodology resulted in the inhibition of E2-induced breast cancer cell proliferation. Overall these studies underscore the importance of PTa in estrogen-induced breast cell proliferation.
Therapie epithelialer Tumoren (2008)

Weltweit ist eine Zunahme der Inzidenz der epithelialen Hauttumoren um 8 % jährlich zu vermerken. Die häufigsten Vertreter stellen die aktinische Keratose, das Basalzellkarzinom und das Plattenepithelkarzinom dar. UV-Exposition gilt als der wichtigste Risikofaktor, so entstehen epitheliale maligne Tumoren meist auf chronisch sonnenexponierter Haut (Gesicht, Kopfhaut, Handrücken) als Folge kumulativer UV-Schädigung. Eine chronisch lichtexponierte Region weist häufig transformierte Keratinozyten in verschiedenen Graduierungen, einschließlich subklinischer Läsionen, auf. Topische Therapieformen wie Imiquimod, Diclofenac-Hyaluronsäure und die photodynamische Therapie werden dieser Feldkanzerisierung unterschiedlich gerecht. Eine rechtzeitige Diagnosestellung, zum Beispiel im Rahmen des Hautkrebs-Screenings, ermöglicht den betroffenen Patienten von diesen neuen, nicht invasiven Therapieformen zu profitieren. Bei solitären Läsionen kommen weiterhin die Kryotherapie, Kürettage, Lasertherapie und in Einzelfällen die Röntgen-Weichstrahltherapie zum Einsatz. Mittel der Wahl beim Plattenepithelkarzinom und bei bestimmten Fällen des Basalzellkarzinoms ist die mikrografisch kontrollierte Exzision.
Impact of Mitral Valve Regurgitation Evaluated by Intraoperative Transesophageal Echocardiography on Long-Term Outcomes After Coronary Artery Bypass Grafting (2005)

Even mild MR, identified by intraoperative TEE, predicts worse outcomes after CABG. Revascularization alone did not eliminate the negative long-term effects of mild MR. CABG patients with uncorrected mild or moderate MR are at increased risk for death and heart-failure hospitalization; consideration for surgical repair or more aggressive medical management and follow-up is warranted.
Engineering design: A powerful influence on the business success on manufacturing industry (1990)

Paper at the Inst. of Mechanical Engineering Conference on Engineering Design, Harrogate (GB), 22-25 Aug 1989
Online Scaling of NFV Service Chains across Geo-distributed Datacenters (2016)

Network Function Virtualization (NFV) is an emerging paradigm that turns hardware-dependent implementation of network functions (i.e., middleboxes) into software modules running on virtualized platforms, for significant cost reduction and ease of management. Such virtual network functions (VNFs) commonly constitute service chains, to provide network services that traffic flows need to go through. Efficient deployment of VNFs for network service provisioning is key to realize the NFV goals. Existing efforts on VNF placement mostly deal with offline or one-time placement, ignoring the fundamental, dynamic deployment and scaling need of VNFs to handle practical time-varying traffic volumes. This work investigates dynamic placement of VNF service chains across geo-distributed datacenters to serve flows between dispersed source and destination pairs, for operational cost minimization of the service chain provider over the entire system span. An efficient online algorithm is proposed, which consists of two main components: (1) A regularization-based approach from online learning literature to convert the offline optimal deployment problem into a sequence of one-shot regularized problems, each to be efficiently solved in one time slot; (2) An online dependent rounding scheme to derive feasible integer solutions from the optimal fractional solutions of the one-shot problems, and to guarantee a good competitive ratio of the online algorithm over the entire time span. We verify our online algorithm with solid theoretical analysis and trace-driven simulations under realistic settings.
Optimizing the Roles of Unit and Non-unit Protection Methods Within DC Microgrids (2012)

The characteristic behavior of physically compact, multiterminal dc networks under electrical fault conditions can produce demanding protection requirements. This represents a significant barrier to more widespread adoption of dc power distribution for microgrid applications. Protection schemes have been proposed within literature for such networks based around the use of non-unit protection methods. This paper shows however that there are severe limitations to the effectiveness of such schemes when employed for more complex microgrid network architectures. Even current differential schemes, which offer a more effective, though costly, protection solution, must be carefully designed to meet the design requirements resulting from the unique fault characteristics of dc microgrids. This paper presents a detailed analysis of dc microgrid behavior under fault conditions, illustrating the challenging protection requirements and demonstrating the shortcomings of non-unit approaches for these applications. Whilst the performance requirements for the effective operation of differential schemes in dc microgrids are shown to be stringent, the authors show how these may be met using COTS technologies. The culmination of this work is the proposal of a flexible protection scheme design framework for dc microgrid applications which enables the required levels of fault discrimination to be achieved whilst minimizing the associated installation costs.
Atomic imaging of nickel oxide with nonmagnetic, ferromagnetic and antiferromagnetic tips (2006)

The (001) surface of NiO, an antiferromagnet at room temperature, was investigated under ultra-high vacuum conditions with frequency modulation atomic force microscopy (FM-AFM). The antiferromagnetic coupling between ions leads to a spin superstructure on (001) surfaces. Exchange interaction between the probe of a force microscope and the NiO (001) surface should allow to image spin superstructures in real space. The surface was imaged with three different probing tips: nonmagnetic W tips, ferromagnetic Co tips and antiferromagnetic NiO tips - and atomic resolution was achieved with all three of them in various distance regimes and in several channels. Evidence for spin contrast was obtained in experiments that utilize NiO tips and oscillation amplitudes in the A-regime, where optimal signal-to-noise ratio is expected. The spin contrast is weaker than expected and only visible in Fourier space images.
Nanoparticles in sentinel lymph node mapping (2009)

The lymph nodes and lymphatic vessels are more difficult to access than most vascular structures. Interstitial injection of imaging agents is often necessary to opacify the lymphatics. Traditionally, radionuclide methods of sentinel node imaging have dominated this field, however, limitations in resolution and exposure to radiation have encouraged the development of newer imaging methods. Among these are magnetic resonance lymphography in which a Gadolinium labeled nanoparticle is injected and imaged providing superior anatomic resolution and assessment of lymphatic dynamics. Optical imaging employing various nanoparticles including quantum dots also provide the capability of mapping each lymphatic basin in another "color". Taken together this "toolbox" of lymphatic imaging agents is poised to improve our understanding of the lymphatic system.
Anti-HIV Tigliane Diterpenoids from <i>Wikstroemia scytophylla</i> (2020)

During a chemical investigation of <i>Wikstroemia scytophylla</i>, three new [wikstrocins A-C (<b>1</b>-<b>3</b>)] and three known tigliane diterpenoids (<b>4</b>-<b>6</b>) were isolated. The structures of the new compounds were elucidated from extensive physiochemical and spectroscopic analysis. The correlations between the ECD Cotton effects and B ring structures of tiglianes were also evaluated. The isolated compounds were assessed for their anti-HIV activity against HIV-1 infection of MT4 cells, and two compounds (<b>4</b> and <b>6</b>) showed potent anti-HIV activity with IC<sub>50</sub> values of 3.8 and 12.8 nM, respectively.
Quasi‐Steady‐State Polarization Reveals the Interplay of Capacitive and Faradaic Processes in Capacitive Deionization (2017)

Abstract We employ slow cyclic voltammetry to study the quasi‐steady‐state capacitive deionization (CDI) of aerated 10 mM NaCl from V cell =−0.2 to 2 V. The method allows for the deconvolution of capacitive and faradaic processes, which are significant even at low voltage, in conjunction with pH, conductivity, dissolved oxygen (DO), and electrode potential measurements. The pH at three locations and effluent DO data identify asymmetric electrosorption in the cell configured with pristine activated carbon electrodes, where charge is irreversibly consumed to produce H + /OH − instead of reversibly adsorbing Cl − /Na + . Implementing a reference electrode resolves ion adsorption as a function of the individual potential at each electrode. Near‐electrode pH probes reveal pH environments that diverge by up to 8 units during cell polarization and allow more accurate calculation of faradaic redox potentials in a flow‐by CDI cell. In the aerated NaCl solution that will be relevant to industrial‐scale water treatment, we find that DO reduction occurs to a greater degree than Na + adsorption at the cathode until DO removal becomes mass transfer limited at &lt;−0.2 V vs. SHE. Two cell architectures – flow‐by and flow‐through – corroborate our findings. Finally, we reconcile all measurements to generate a map displaying how the potential is partitioned amongst the capacitive and faradaic processes occurring during CDI operation over a 2.2 V window.