gebhart/patrepeval huggingface dataset:
Management of premature infants with extensive bowel resection with high volume enteral infusates. (1995)

To avoid long-term parenteral nutrition (PN), three premature infants with extensive bowel resections were fed high volume enteral infusates (HVEI). Following surgery an elemental hypo-osmolar gastric infusate was initiated. The infants were weaned of PN and were subsequently maintained on HVEI feeding. Rather than using the volume of the ileostomy outputs or the presence of reducing substances as guides for adjustment of enteral intake, we tolerated large ileostomy output and focused instead on the patients' hydration, serum electrolytes and acid base status. During HVEI feeding, the patients had sustained weight gain, while the mean +/- SD enteral intakes were 373 +/- 67, 689 +/- 132, and 415 +/- 108 ml/kg per day; osmolarity of enteral infusates were 250 +/- 25, 225 +/- 40 and 228 +/- 27 mosmol/l; caloric intakes were 163 +/- 29, 258 +/- 54, and 153 +/- 44 Kcal/kg per day; and ileostomy outputs were 113 +/- 47, 228 +/- 59, and 175 +/- 69 ml/kg per day, respectively. Gut adaptation lasted 122, 141, and 205 days, respectively. Re-anastomoses of the intestines were performed at the ages of 8, 78, and 36 months. At 18, 108, and 58 months, infants' weights were in the 50th, 20th, and 5th percentiles, respectively. No infant developed cirrhosis. High volume enteral infusate feeding in infants with extensive bowel resection may help achieve gut adaptation and may serve as an alternative nutrition modality to prolonged PN.
TheInteraction ofFRCandVentilation on Occlusion Pressure inConscious Man (1977)

Analytical andexperimental results relating theinteraction offunctional residual capacity (FRC)andventilation (V)onocclusion pressure inconscious manarepresented. Ananalytical modelwasde- veloped relating theairway pressure measured 100msafter occlusion (P100) withFRCandVjust before occlusion. Byrelating thechange in diaphragmatic force withtimeduring breathing tothat during occlusion, itwasfoundthatP100andIFRCcould belinearly related. Inorder totest this model, 16normal adult subjects withdifferent FRCvalues (2.0to5.61)werestudied during periods ofincreasing ventilation. Subjects increased Vbyrebreathing amixture of7%CO2and93%02. Neither AP100/APC02 norAV/APC02 could becorrelated toFRC since thedifferences inmotoneuron activity inresponse tohypercapnia wereprobably greater thanthevariations inFRC. Linear regression analysis onall16subjects demonstrated asignificant effect ofFRCon therelationships P100versus V,andAP1o0/APClO2 versus AV/APC;2. Theseexperimental findings wereinclose agreement withanalytical predictions andsuggest thatsubjects withlarger FRCvalues havea greater ventilation andventilatory response forthesameocclusion pressure andocclusion pressure response, respectively.
Posttranslational processing of defensins in immature human myeloid cells (1992)

Abstract Human neutrophil promyelocytes synthesize, process, and package several microbicidal proteins, including the highly abundant defensins, into their azurophil granules. As deduced from their cDNA sequences, defensins are initially synthesized as 94 amino acid (aa) precursors that must undergo extensive processing. We performed metabolic labeling studies of defensin synthesis in the human promyelocytic cell line HL- 60 and in chronic myeloid leukemia cells, and showed that preprodefensins are processed to mature 29 to 30 aa defensins over 4 to 24 hours via two major intermediates: a 75 aa prodefensin generated by the cleavage of the signal sequence, and a 56 aa prodefensin that results from a subsequent preaspartate proteolytic cleavage. Almost all of the 75 aa form was found in the cytoplasmic/microsomal fraction, whereas the 56 aa prodefensin and mature defensins predominated in the granule-enriched fraction. The 75 aa prodefensin was also selectively released into the culture supernatant. Treatment of HL-60 cells with monensin, chloroquine, or ammonium chloride, substances that neutralize acidic subcellular compartments, partially blocked conversion of the 75 aa prodefensin into 56 aa prodefensin, but did not increase the extracellular release of the 75 aa form. Further studies will be required to determine the role of this processing pathway in subcellular targeting to azurophil granules and avoidance of autocytotoxicity.
Improved real‐time tagged MRI using REALTAG (2019)

Tag persistence is substantially increased in intermittently tagged real-time MRI by using the improved REALTAG method. This makes it possible to capture longer motion patterns in the tongue, such as cross-word vowel-to-vowel transitions, and provides a powerful new window to study tongue biomechanics.
The Superdominant Minor Histocompatibility Antigen (MHAg) H60 Recognized by CD8 T Cells Fails to Elicit Lethal Graft Versus Host Disease (GVHD) Regardless of Its Tissue Expression Pattern (102.26) (2007)

Abstract Studies both in mice and humans have argued that immunodominant MHAg eliciting CD8 T cells cause increased risk for GVHD. We have shown that the H60 MHAg is remarkably immunodominant in that an overwhelmingly predominant CD8 T cell response developed after the transfer of T cells and bone marrow (BM) into MHAg-mismatched lethally irradiated recipients is directed against H60. Here we address whether H60 is a barrier to lethal (L) GVHD. Matching of donor cells and recipients for H60 while remaining disparate for all other MHAg failed to result in improved survival, indicating that H60 is not a barrier for LGVHD. Expression of H60 is normally limited to hematopoietic tissues, possibly explaining H60’s inertness in LGVHD. To broaden its expression, we produced transgenic mice expressing H60 driven by a tissue-ubiquitous cassette. We then evaluated whether H60 expressed broadly in recipients resulted in GVHD. Naïve B6 T cells transferred into B6-H60 transgenic or congenic mice failed to show any evidence of GVHD regardless of a robust anti-H60 CD8 T cell response. Augmentation of the response to H60 by preimmunization, resulting on over 50% of the CD8 T cell compartment being H60-specific in GVHD target organs, an failed to result in LGVHD. The overall results are inconsistent with a recent report (B. Kappel, et al. Blood, 2006.107:2045) and clearly indicate that potent CD8 T cell responses to MHAg are remarkably inert in GVHD.
(Atrial fibrillation as risk factor in patients after cardiac arrest for ventricular fibrillation) (2022)

Fibrilace sĂ­nĂ­ je nejÄastÄjĹĄĂ­ arytmiĂ­ vyskytujĂ­cĂ­ se v dospÄlĂŠ populaci. V ĹadÄ studiĂ­ byla sledovĂĄna spojitost mezi fibrilacĂ­ sĂ­nĂ­ a dalĹĄĂ­mi onemocnÄnĂ­mi srdce vÄetnÄ nĂĄhlĂŠ srdeÄnĂ­ smrti. CĂ­l: CĂ­lem naĹĄĂ­ studie bylo zanalyzovat vĂ˝skyt fibrilace sĂ­nĂ­ jako rizikovĂŠho faktoru u nemocnĂ˝ch po obÄhovĂŠ zĂĄstavÄ pro fibrilaci komor. Metody: Do naĹĄĂ­ retrospektivnĂ­, monocentrickĂŠ studie bylo zaĹazeno 514 osob po mimonemocniÄnĂ­ obÄhovĂŠ zĂĄstavÄ, kteĹĂ­ byli hospitalizovĂĄni na kardiologickĂŠ jednotce intenzivnĂ­ pĂŠÄe. Pacienti podstoupili standardnĂ­ poresuscitaÄnĂ­ pĂŠÄi vÄetnÄ koronarografickĂŠho a echokardiografickĂŠho vyĹĄetĹenĂ­. Z anamnestickĂ˝ch ĂşdajĹŻ byla zjiĹĄtÄna pĹĂ­tomnost komorbidit a uĹžĂ­vanĂŠ medikace pĹed vlastnĂ­ zĂĄstavou obÄhu se zamÄĹenĂ­m na vĂ˝skyt fibrilace sĂ­nĂ­. Tyto Ăşdaje byly nĂĄslednÄ dĂĄle vyhodnoceny. VĂ˝sledky: PĹi srovnĂĄnĂ­ pacientĹŻ s fibrilaÄnĂ­ zĂĄstavou s akutnĂ­m koronĂĄrnĂ­m syndromem (VF s AKS) s pacienty s fibrilaÄnĂ­ zĂĄstavou bez akutnĂ­ho koronĂĄrnĂ­ho syndromu (VF bez AKS) byl jednoznaÄnÄ prokĂĄzĂĄn vyĹĄĹĄĂ­ vĂ˝skyt fibrilace sĂ­nĂ­ ve skupinÄ VF bez AKS oproti skupinÄ VF s AKS (celkovĂ˝ vĂ˝skyt fibrilace sĂ­nĂ­ [FS] 106 pacientĹŻ, 45,96 % Ă 24 pacientĹŻ, 13,95 %, p &lt; 0,0001). V pĹĂ­padÄ sledovanĂ˝ch komorbidit bylo ve skupinÄ VF bez AKS statisticky vĂ˝znamnÄ vÄtĹĄĂ­ zastoupenĂ­ pacientĹŻ s jiĹž znĂĄmou ischemickou chorobou srdeÄnĂ­ (ICHS) a arteriĂĄlnĂ­ hypertenzĂ­. Ve sledovanĂŠ medikaci uĹžĂ­vali pacienti statisticky vĂ˝znamnÄ vĂ­ce inhibitory angiotenzin konvertujĂ­cĂ­ho enzymu (ACEI)/sartany, beta-blokĂĄtory, digoxin, diuretika, antiagregaÄnĂ­ i antikoagulaÄnĂ­ terapii a statiny. PĹi srovnĂĄnĂ­ pacientĹŻ s fibrilaÄnĂ­ zĂĄstavou s akutnĂ­m koronĂĄrnĂ­m syndromem a s ischemickou chorobou srdeÄnĂ­ (VF s AKS, s ICHS) s pacienty s fibrilaÄnĂ­ zĂĄstavou bez akutnĂ­ho koronĂĄrnĂ­ho syndromu a bez ischemickĂŠ choroby srdeÄnĂ­ (VF bez AKS, bez ICHS) byl prokĂĄzĂĄn statisticky vĂ˝znamnÄ vyĹĄĹĄĂ­ vĂ˝skyt celkovĂŠ fibrilace sĂ­nĂ­ ve skupinÄ VF bez AKS a bez ICHS (45 pacientĹŻ, 39,13 % Ă 4 pac., 16,67 %, p = 0,0376). Ve sledovanĂ˝ch komorbiditĂĄch nebyl zaznamenĂĄn vĂ˝znamnĂ˝ rozdĂ­l. Ve sledovanĂŠ medikaci byl vĂ˝znamnĂ˝ rozdĂ­l v uĹžĂ­vĂĄnĂ­ beta-blokĂĄtorĹŻ, antiagregaÄnĂ­ terapie a statinĹŻ, coĹž je dĂĄno pĹĂ­tomnou premorbidnĂ­ ICHS. ZĂĄvÄr: NaĹĄe prĂĄce potvrzuje fibrilaci sĂ­nĂ­ jako vĂ˝znamnĂ˝ rizikovĂ˝ faktor nĂĄhlĂŠ srdeÄnĂ­ smrti u pacientĹŻ s fibrilaÄnĂ­ zĂĄstavou obÄhu bez akutnĂ­ho koronĂĄrnĂ­ho syndromu oproti pacientĹŻm s akutnĂ­m koronĂĄrnĂ­m syndromem. ObdobnÄ potvrzuje vyĹĄĹĄĂ­ vĂ˝skyt fibrilace sĂ­nĂ­ u pacientĹŻ po fibrilaÄnĂ­ zĂĄstavÄ bez pĹĂ­tomnĂŠ ICHS a akutnĂ­ho koronĂĄrnĂ­ho syndromu oproti pacientĹŻm s tÄmito onemocnÄnĂ­mi, coĹž potvrzuje fibrilaci sĂ­nĂ­ jako nezĂĄvislĂ˝ rizikovĂ˝ faktor nĂĄhlĂŠ srdeÄnĂ­ smrti. &#169; 2022, ÄKS.
“Determining optical flow”: a retrospective (1994)

This chapter contains sections titled: Overview, Origins, Variational approach to machine vision problems, False leads, Unfortunate side-effects, What was left out, Optical flow and the motion field, Where did the work go from there, What can be built more easily as a result of the paper?, References
New developments in the synthesis of oligonucleotide-peptide conjugates (2007)

The stability of oligodeoxynucleotides to trifluoroacetic acid is studied. Pyrimidine oligonucleotides were stable in the conditions used for the removal of t-butyl groups. Oligonucleotide-3'-peptide conjugates carrying pyrimidine oligonucleotides are prepared stepwise using peptide-supports and Fmoc, t-butyl strategy. Using this strategy we have prepared an oligonucleotide-peptide conjugate containing as peptide the leucine-rich fragment of FOS, a transcription factor involved in many important cellular processes. This conjugate has a long peptide sequence with a large number of trifunctional amino acids.
A Game-Theoretic Approach for Exploiting Multiuser Diversity in Cooperative Slotted Aloha (2008)

Multiuser diversity gains can be achieved by assigning channels to users with better channel quality in multiuser systems. To avoid the extensive information exchange required for centralized approaches, we propose a distributed fair pricing strategy for a slotted Aloha system in which users act selfishly to improve their own utilities for both the collision model and the multipacket reception (MPR) model. Based on a game theoretic framework, we show that multiuser diversity gains can be achieved by appropriately designing the Nash equilibrium thresholds for the selfish users to preserve the throughput and revenue achieved in the classical slotted Aloha systems. The network enforces fairness among different users by employing a pricing policy that favors equal access probabilities. Our simulation results show that significant multiuser diversity gains are achieved in terms of energy consumption and/or spectral efficiency.
Random Threshold Voltage Variability Induced by Gate-Edge Fluctuations in Nanoscale Metal–Oxide–Semiconductor Field-Effect Transistors (2009)

A very rapid method of estimating the effect of gate-edge fluctuation on threshold voltage (Vth) variability in metal–oxide–semiconductor field-effect transistors (MOSFETs) is proposed. An empirical model is developed, in which correlation width (Wc) from gate line-width roughness (LWR) is a key parameter of the model. The validity of the model is confirmed using the measured data and an autoregressive model. Wc is extracted from the gate line-edge shape depicted in a scanning electron microscope (SEM) image. This method is very useful for the intuitive understanding of the gate-edge fluctuation effect on Vth variability.
Mixed transition metal-gold cluster hydrides (1986)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTMixed transition metal-gold cluster hydridesBruce D. Alexander, Brian J. Johnson, Steven M. Johnson, Albert L. Casalnuovo, and L. H. PignoletCite this: J. Am. Chem. Soc. 1986, 108, 15, 4409–4417Publication Date (Print):July 1, 1986Publication History Published online1 May 2002Published inissue 1 July 1986https://pubs.acs.org/doi/10.1021/ja00275a030https://doi.org/10.1021/ja00275a030research-articleACS PublicationsRequest reuse permissionsArticle Views300Altmetric-Citations42LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
Epoxy Based Nanocomposites with Fully Exfoliated Unmodified Clay: Mechanical and Thermal Properties (2010)

The unmodified clay has been fully exfoliated in epoxy resin with the aid of a novel ultrafine full-vulcanized powdered rubber. Epoxy/rubber/clay nanocomposites with exfoliated morphology have been successfully prepared. The microstructures of the nanocomposites were characterized by means of X-ray diffraction and transmission electron microscopy. It was found that the unmodified clay was fully exfoliated and uniformly dispersed in the resulting nanocomposite. Characterizations of mechanical properties revealed that the impact strength of this special epoxy/rubber/clay nanocomposite increased up 107% over the neat epoxy resin. Thermal analyses showed that thermal stability of the nanocomposite was much better than that of epoxy nanocomposite based on organically modified clay.
Convenient Synthesis of Various Terheterocyclic Compounds by Pd(0)-Catalyzed Coupling Reactions (1990)

y o c c u r r i
High school Internship Program in Integrated Mathematical Oncology (HIP IMO) – five-year experience at Moffitt Cancer Center (2020)

Abstract Modern cancer research, and the wealth of data across multiple spatial and temporal scales, has created the need for researchers that are well-versed in the life sciences (cancer biology, developmental biology, immunology), medical sciences (oncology) and natural sciences (mathematics, physics, engineering, computer sciences). College undergraduate education is traditionally provided in disciplinary silos, which creates a steep learning curve at the graduate and postdoctoral levels that increasingly bridge multiple disciplines. Numerous colleges have begun to embrace interdisciplinary curricula, but students who double-major in mathematics (or other quantitative sciences) and biology (or medicine) remain scarce. We identified the need to educate junior and senior high school students about integrating mathematical and biological skills, through the lens of mathematical oncology, to better prepare students for future careers at the interdisciplinary interface. The High school Internship Program in Integrated Mathematical Oncology (HIP IMO) at Moffitt Cancer Center has so far trained 59 students between 2015 and 2019. We report here on the program structure, training deliverables, curriculum, and outcomes. We hope to promote such interdisciplinary educational activities early in a student’s career.
ChemInform Abstract: Palladium‐Catalyzed Intramolecular Nucleophilic Addition of Allylic Species, Generated from Allene, to Aryl Aldehydes and Ketones. (2000)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Ultra-Low-Dropout Linear Regulator (2011)

A radiation-tolerant, ultra-low-dropout linear regulator can operate between -150 and 150 C. Prototype components were demonstrated to be performing well after a total ionizing dose of 1 Mrad (Si). Unlike existing components, the linear regulator developed during this activity is unconditionally stable over all operating regimes without the need for an external compensation capacitor. The absence of an external capacitor reduces overall system mass/volume, increases reliability, and lowers cost. Linear regulators generate a precisely controlled voltage for electronic circuits regardless of fluctuations in the load current that the circuit draws from the regulator.
Models of diffusion of neuromessenger, nitric oxide, in brain (2002)

As a neuronal messenger molecule, nitric oxide (NO) carries out the signaling tasks by diffusing in the extracellular space surrounding the neurons. To understand diffusion process of this messenger molecule in the brain, we have developed two theoretical models that describe the concentration profiles of NO when generated from single or multiple sources. The multi-source model is developed using a bidomain concept in which multiple NO source and nonsource regions are separately considered. With these models, the diffusion times and concentration profiles of NO in the extracellular space are derived.
Real time scatterometry: a new metrology for in situ microelectronics process control (2010)

In situ and real time control of the different process steps in semiconductor device manufacturing becomes a critical challenge, especially for the lithography and plasma etching processes. Real time scatterometry is among the few solutions able to meet the requirement for in line monitoring. In this paper we demonstrate that real time scatterometry can be used as a real time monitoring technique during the resist trimming process. For validation purposes the real time scatterometry measurements are compared with 3D Atomic Force Microscopy measurements made in the same process conditions. The agreement between both is excellent.
Molecular Method for Discrimination between <i>Francisella tularensis</i> and <i>Francisella</i> -Like Endosymbionts (2008)

Environmental studies on the distribution of Francisella spp. are hampered by the frequency of Francisella-like endosymbionts that can produce a misleading positive result. A new, efficient molecular method for detection of Francisella tularensis and its discrimination from Francisella-like endosymbionts, as well as two variants associated with human disease (unusual F. tularensis strain FnSp1 and F. tularensis subsp. novicida-like strain 3523), is described. The method is highly specific and sensitive, detecting up to one plasmid copy or 10 genome equivalents.
&lt;title&gt;Large electro-optic coefficient observed in ion-exchanged potassium titanyl phosphate waveguides&lt;/title&gt; (1996)

We report the observation of an anomalously large electro-optic coefficient in potassium titanyl phosphate (KTiOPO<SUB>4</SUB>, KTP) waveguides fabricated under various conditions. An interferometric method was used to measure the effective electro-optic coefficient r<SUB>33</SUB> in the waveguides by measuring the phase retardation of an optical mode when a voltage is applied across the substrate. We observe that at low frequency the waveguide electro-optic coefficient can be higher than the bulk value by a factor up to about 100. Since KTP crystals are known to have a high concentration of mobile ions, a model relating the mobile charges, space charge fields, and observed enhancement in r<SUB>33</SUB> is proposed to explain the mechanism of this effect. Possible device application and long term effects on system operation are also discussed.
Auraptene suppresses inflammatory responses in activated <scp>RAW</scp>264 macrophages by inhibiting p38 mitogen‐activated protein kinase activation (2013)

Our findings indicate that auraptene exhibits anti-inflammatory properties by suppressing the production of inflammatory factors that mediate the interaction between adipocytes and macrophages, suggesting that auraptene is a valuable food-derived compound with a potential to attenuate chronic inflammation in adipose tissue and to improve obesity-related insulin resistance.
Role of Absorbed Solvent in Polymer Pen Lithography (2013)

We report on the dynamic role of solvents in molecular printing and show that material transport can be mediated by both environmental solvent (i.e., humidity) and solvent absorbed in the pen. To explore the transport of materials in the absence of environmental solvent, a hydrophobic polymer was patterned using a polydimethylsiloxane (PDMS) pen array that had been soaked in undecane, a nonpolar solvent that readily absorbs into PDMS. We also explored the patterning of the hydrophilic polymer polyethylene glycol (PEG) and found that, even though PDMS only absorbs trace amounts of water, soaking a PDMS pen array in water enables PEG deposition in completely dry environments for over 2 h. We find that the length of time one can pattern in a dry environment is determined by the availability of absorbed solvent, a relationship that we elucidate by comparing the performance of pens with varying ability to absorb water. Furthermore, a calculation accounting for the dynamics of retained water captures these effects completely, allowing for generalization of this result to other solvents and providing a way to tune the desired solvent retention profile. Taken together, this work explores the subtle and dynamic role of solvent on molecular printing and provides an alternative to strict environmental humidity control for reliable molecular printing.
Zero-crossing edge detection for visual force measurement in assembly of MEMS devices (2006)

In this paper, a new visual force sensor is proposed to measure the microforces acting upon the jaws of passive, compliant microgrippers, used to construct out-of-plane 3-D microstructures. The vision-based force measurement technique is reduced to determining the deflections of the microgripper jaws during the microassembly process. A computer vision system is used to measure the deflections in the gripper's jaws during the joining and grasping processes. A mathematical model of the microgripper system was developed where a relation between the force and the jaw displacement was deduced. Image processing methods, such as Zero-crossing Laplacian of Gaussian edge detection and region-filling, are used. The relative positions of the microgripper jaws, with respect to the gripper's pad, are determined by means of object recognition. Performed experiments confirm the success of the proposed sensor and verify that the measured deflections comply with the profile variations of the microgripper.