gebhart/patrepeval huggingface dataset:
Fine-Grained Vehicle Perception via 3D Part-Guided Visual Data Augmentation (2020)

Holistically understanding an object and its 3D movable parts through visual perception models is essential for enabling an autonomous agent to interact with the world. For autonomous driving, the dynamics and states of vehicle parts such as doors, the trunk, and the bonnet can provide meaningful semantic information and interaction states, which are essential to ensuring the safety of the self-driving vehicle. Existing visual perception models mainly focus on coarse parsing such as object bounding box detection or pose estimation and rarely tackle these situations. In this paper, we address this important autonomous driving problem by solving three critical issues. First, to deal with data scarcity, we propose an effective training data generation process by fitting a 3D car model with dynamic parts to vehicles in real images before reconstructing human-vehicle interaction (VHI) scenarios. Our approach is fully automatic without any human interaction, which can generate a large number of vehicles in uncommon states (VUS) for training deep neural networks (DNNs). Second, to perform fine-grained vehicle perception, we present a multi-task network for VUS parsing and a multi-stream network for VHI parsing. Third, to quantitatively evaluate the effectiveness of our data augmentation approach, we build the first VUS dataset in real traffic scenarios (e.g., getting on/out or placing/removing luggage). Experimental results show that our approach advances other baseline methods in 2D detection and instance segmentation by a big margin (over 8%). In addition, our network yields large improvements in discovering and understanding these uncommon cases. Moreover, we have released the source code, the dataset, and the trained model on Github (https://github.com/zongdai/EditingForDNN).
Using Agent-Based Modelling to Predict the Role of Wild Refugia in the Evolution of Resistance of Sea Lice to Chemotherapeutants (2015)

A major challenge for Atlantic salmon farming in the northern hemisphere is infestation by the sea louse parasite Lepeophtheirus salmonis. The most frequent method of controlling these sea louse infestations is through the use of chemical treatments. However, most major salmon farming areas have observed resistance to common chemotherapeutants. In terrestrial environments, many strategies employed to manage the evolution of resistance involve the use of refugia, where a portion of the population is left untreated to maintain susceptibility. While refugia have not been deliberately used in Atlantic salmon farming, wild salmon populations that migrate close to salmon farms may act as natural refugia. In this paper we describe an agent-based model that explores the influence of different sizes of wild salmon populations on resistance evolution in sea lice on a salmon farm. Using the model, we demonstrate that wild salmon populations can act as refugia that limit the evolution of resistance in the sea louse populations. Additionally, we demonstrate that an increase in the size of the population of wild salmon results in an increased effect in slowing the evolution of resistance. We explore the effect of a population fitness cost associated with resistance, finding that in some cases it substantially reduces the speed of evolution to chemical treatments.
A comparative bear model for immobility-induced osteopenia. (1998)

The National Institutes of Health (NIH) and the National Aeronautics and Space Administration (NASA) are seeking solutions to the human problem of osteopenia, or immobility-induced bone loss. Bears, during winter dormancy, appear uniquely exempted from the debilitating effects of immobility osteopenia. NIH and ESA, Inc. are creating a large database of metabolic information on human ambulatory and bedrest plasma samples for comparison with metabolic data obtained from bear plasma samples collected in different seasons. The database generated from NASA's HR113 human bedrest study showed a clear difference between plasma samples of ambulatory and immobile subjects through cluster analysis using compounds determined by high performance liquid chromatography with coulometric electrochemical array detection (HPLC-EC). We collected plasma samples from black bears (Ursus americanus) across 4 seasons and from 3 areas and subjected them to similar analysis, with particular attention to compounds that changed significantly in the NASA human study. We found seasonal differences in 28 known compounds and 33 unknown compounds. A final database contained 40 known and 120 unknown peaks that were reliably assayed in all bear and human samples; these were the primary data set for interspecies comparison. Six unidentified compounds changed significantly but differentially in wintering bears and immobile humans. The data are discussed in light of current theories regarding dormancy, starvation, and anabolic metabolism. Work is in progress by ESA Laboratories on a larger database to confirm these findings prior to a chemical isolation and identification effort. This research could lead to new pharmaceuticals or dietary interventions for the treatment of immobility osteopenia.
Modeling Nickel Electrowinning with Electrode Diaphragms Based on Nernst-Plank Equation and a Volume Force Form of Darcy's Law (2019)

The Ni electrowinning process with electrode diaphragms was simulated with an Electrochemical-Computational Fluid Dynamic model by considering a two-phase flow, mass transport, and electrochemical reactions. The effects of electrode diaphragms on the fluid flow, concentration, voltage drop, and current distribution were analyzed based on the simulation results. Results show that the electrode diaphragms have significant effects on the fluid flow and voltage drop in the electrolyte. The electrode diaphragms greatly reduced the strong convective flow caused by rising bubbles in the cell, and thus reduce the transport of H+ (generated at the anode) to the cathode. Based on this model, the effects of different operating parameters on the electrolyte potential and cathode current distribution have been analyzed. The results show that the cell temperature of 60°C, Ni concentration of 80 g/L, and a relatively low current density are the most favorable compared with other settings in the simulation for decreasing the electrolyte voltage drop and reducing the roughness of the deposition.
Expression of Matrix Metalloproteinases and Tissue Inhibitors of Metalloproteinases in Reactive and Neoplastic Lymphoid Cells (1997)

We have studied the expression of gelatinase A, gelatinase B, interstitial collagenase, tissue inhibitor of metalloproteinase (TIMP)-1 and TIMP-2 in reactive lymphoid cells, as well as in a series of cell lines derived from neoplasms of B- and T-cell lineage. Using both Northern blot analysis and zymography, gelatinase B activity was detected by zymography in two Burkitt cell lines and in a tonsillar cell suspension, while gelatinase A and interstitial collagenase activities were not detected by either method. TIMP-1 expression was demonstrated by Northern blot analysis in the multipotential neoplastic K-562 cell line, the high grade Burkitt's B-cell lymphoma lines, isolated tonsillar B cells and at low levels in peripheral blood T cells, but was not expressed in any of the neoplastic T-cell lines or isolated peripheral blood B cells. In contrast, TIMP-2 expression was restricted to tissues containing cells of T-cell lineage with high levels being observed in the neoplastic T-cell lines and lower levels in normal peripheral blood T cells and hyperplastic tonsil. Expression of TIMP-1 and TIMP-2 was confirmed at the protein level by reverse zymography and immunofluorescence assays using antihuman TIMP polyclonal antibodies. Expression of gelatinase B by the high grade B-cell Burkitt's lymphoma cell lines is consistent with previous findings in large cell immunoblastic lymphomas and indicates that this enzyme may play an important role in high grade non-Hodgkin's lymphomas. TIMP expression correlated with cell lineage in that TIMP-1 was primarily observed in B cells and TIMP-2 was restricted to T cells.
Temperature and wavelength drift tolerant WDM transmission and routing in on-chip silicon photonic interconnects (2022)

We demonstrate a temperature and wavelength shift resilient silicon transmission and routing interconnect system suitable for multi-socket interconnects, utilizing a dual-strategy CLIPP feedback circuitry that safeguards the operating point of the constituent photonic building blocks along the entire on-chip transmission-multiplexing-routing chain. The control circuit leverages a novel control power-independent and calibration-free locking strategy that exploits the 2<sup>nd</sup> derivative of ring resonator modulators (RMs) transfer function to lock them close to the point of minimum transmission penalty. The system performance was evaluated on an integrated Silicon Photonics 2-socket demonstrator, enforcing control over a chain of RM-MUX-AWGR resonant structures and stressed against thermal and wavelength shift perturbations. The thermal and wavelength stress tests ranged from 27°C to 36°C and 1309.90 nm to 1310.85 nm and revealed average eye diagrams Q-factor values of 5.8 and 5.9 respectively, validating the system robustness to unstable environments and fabrication variations.
Human T lymphocyte subset identification according to avidity for sheep erythrocytes and rosetting capacity with allogeneic red blood cells. (1977)

Peripheral blood T lymphocytes of healthy adults were separated in appropriate Ficoll-Hypaque mixtures according to their avidity for sheep red blood cells (SRBC) and re-rosetted with both SRBC and human red blood cells (HRBC). The results showed that separation procedures causing relative depletion of lymphocytes with high avidity for SRBC led to a parallel increase in the percentage of cells forming rosettes with HRBC. Separation procedures leading to almost complete depletion of cells forming rosettes with SRBC also almost completely eliminated cells forming rosettes with HRBC. The overall data suggest that circulating T cells of healthy adults can be divided into two subsets according to their avidity for SRBC. T lymphocytes with low avidity for SRBC preferentially express receptors for HRBC. These data are presented as further evidence of T lymphocyte heterogeneity.
Male Gender is Associated With Excessive IL-6 Expression Following Severe Injury (2008)

Persistently elevated IL-6 levels in males are associated with a higher rate of MOF. It is not known if this excessive IL-6 expression in males is causal or only a marker for poor outcome. Further studies are required to elucidate if this early, persistent IL-6 expression is responsible for the gender-based differential outcomes after injury.
Multiple Infections with Seasonal Influenza A Virus Induce Cross‐Protective Immunity against A(H1N1) Pandemic Influenza Virus in a Ferret Model (2010)

These data suggest the reduced incidence and severity of infection with A(H1N1)pdm virus in the adult population during the 2009-2010 influenza season may be a result of previous exposure to seasonal influenza A viruses.
Raman profiles of the stratum corneum define 3 filaggrin genotype–determined atopic dermatitis endophenotypes (2010)

Raman spectroscopy permits rapid and highly accurate stratification of FLG-associated AD. FLG mutations do not influence TEWL within established moderate-to-severe AD.
Multi‐cycle recovery of lactoferrin and lactoperoxidase from crude whey using fimbriated high‐capacity magnetic cation exchangers and a novel “rotor–stator” high‐gradient magnetic separator (2013)

Cerium (IV) initiated "graft-from" polymerization reactions were employed to convert M-PVA magnetic particles into polyacrylic acid-fimbriated magnetic cation exchange supports displaying ultra-high binding capacity for basic target proteins. The modifications, which were performed at 25 mg and 2.5 g scales, delivered maximum binding capacities (Qmax ) for hen egg white lysozyme in excess of 320 mg g(-1) , combined with sub-micromolar dissociation constants (0.45-0.69 µm) and "tightness of binding" values greater than 49 L g(-1) . Two batches of polyacrylic acid-fimbriated magnetic cation exchangers were combined to form a 5 g pooled batch exhibiting Qmax values for lysozyme, lactoferrin, and lactoperoxidase of 404, 585, and 685 mg g(-1) , respectively. These magnetic cation exchangers were subsequently employed together with a newly designed "rotor-stator" type HGMF rig, in five sequential cycles of recovery of lactoferrin and lactoperoxidase from 2 L batches of a crude sweet bovine whey feedstock. Lactoferrin purification performance was observed to remain relatively constant from one HGMF cycle to the next over the five operating cycles, with yields between 40% and 49% combined with purification and concentration factors of 37- to 46-fold and 1.3- to 1.6-fold, respectively. The far superior multi-cycle HGMF performance seen here compared to that observed in our earlier studies can be directly attributed to the combined use of improved high capacity adsorbents and superior particle resuspension afforded by the new "rotor-stator" HGMS design.
Numerical Investigation of Design Strategies to Achieve Perpetual Pavements (2012)

Increasing the hot mix asphalt (HMA) base thickness and modifying the HMA mixture properties to improve the resistance to fatigue cracking are among the most popular methods for achieving long-lasting pavements. Such methods are based on the idea of reducing the tensile strain at the bottom of the HMA layer below the Fatigue Endurance Limit (FEL), a level of strain below which no cumulative damage occurs to the HMA mixture. This study investigates the effectiveness of several design strategies involved in long-life, perpetual pavement design. A 3D Finite Element model of the pavement involving a linear viscoelastic constitutive model for HMA materials and non-uniform tire contact stresses is developed using the commercial finite element program ABAQUS. The effects of asphalt base course thickness and mixture type, rich binder layer, and aggregate subbase layer are examined. Four asphalt base course mixture types - dense graded, polymer modified, high modulus, and standard binder - are studied as a function of the asphalt base course thickness. The results underline a better performance of the high-modulus asphalt base, as compared to the other base course mixtures. The aggregate subbase layer on top of subgrade soil showed a relatively minor effect on the longitudinal and lateral strain response at the bottom of asphalt base course. The addition of a rich binder layer at the bottom of the asphalt base course showed a significant reduction in tensile strains. Tables are provided as a guideline to assess the different alternatives in design of long-life perpetual pavements.
Reducing Fault Current by Using FACTS Devices to Improve Electrical Power Flow (2021)

Today, there is a large increase in the demand for electricity. The transmission and distribution networks, however, cannot fulfill unbound demands due to the scarcity of resources. Power lines have losses which make the situation more unfavorable for maximum power transfer. Implementing a flexible AC transmission system (FACTS) is one of the best ways to reduce line losses. This paper proposes a FACTS-based method for minimizing the fault current in the system. Switchgear and protection equipment also perform better when this is done. Moreover, due to the reduced fault current of the switched system, a larger amount of power can be transmitted. Static synchronous series compensator (SSSC), static synchronous compensator (STATCOM), and unified power flow controller (UPFC) are evaluated in this case. With STATCOM and UPFC, fault currents are significantly reduced. Furthermore, STATCOM and UPFC can also reduce the fault currents in the power system in addition to voltage regulation and power flow control. A MATLAB/Simulink model is used to evaluate the model’s feasibility.
Fourier fluorescence spectrometer for excitation emission matrix measurement (2008)

We demonstrate a fluorescence spectrometer that utilizes principles of Fourier transform spectroscopy to measure excitation emission matrices (EEM) rapidly and with high spectral resolution. For this EEM fluorometer, incoherent excitation light is first input into a differential-delay scanning Michelson interferometer. Light from the output port excites sample fluorescence. The fluorescence remitted from the sample is directed to a second Michelson interferometer, whose differential-delay scanning is synchronized with the first interferometer. The EEM is obtained by two-dimensional Fourier analysis of the detected signal from the output port of the second interferometer. EEM results from the system are verified by comparing with results from a standard spectrometer. The system provides a wide spectral range, adjustable spectral resolution, and fast EEM acquisition speed, which allows EEM's to be acquired in 40 seconds at a spectral resolution of 81-cm-1.
Mapping Water Table Depths using Electromagnetic Induction Methods to Develop Variable Rate Technologies (2011)

Most of the agricultural fields are generally irrigated or drained uniformly without considering the variation in water table depths (WTD). Investigating these depths is important for scheduling irrigation, drainage system designs and water balance models. The objective of this study was to estimate the WTD using electromagnetic induction (EMI) method. Thirty observation wells were installed to calibrate the DualEM-2 for predicting the WTD within a soybean and a pasture field in central Nova Scotia, respectively. The horizontal co-planar (HCP) geometry, perpendicular co-planar (PRP) geometry and WTD were recorded simultaneously from each well for three consecutive days after every significant rainfall. Comprehensive surveys were conducted in selected fields to measure ground conductivity with DualEM-2 and a differential global positioning system (DGPS). The HCP component of the DualEM-2 was better than PRP component for estimating WTD because of its greater sensing depth. The preliminary results showed significant correlations between the actual WTD and HCP measured with DualEM-2 in both fields. The regression equation was utilized to predict WTD from ground conductivity survey data (BEEC: R2 ranged from 0.76 to 0.93; p-value<0.01, Boulden: R2 ranged from 0.69 to 0.85; p-value<0.01).The predicted WTD maps were generated in ArcGIS 9.3 software. This information could also be used for measuring the depletion of WTD, site-specific irrigation and drainage design with time after the application of irrigation or rainfall.
[Activity of various hematopoietic growth factors on acute myeloblastic leukemia blasts]. (1996)

IL-3 and GM-CSF induced self-replication of CFU-L in a half of the cases. This effect was not dependent upon the kind of stimulating agent used (IL-3 or GM-CSF), and appeared unrelated to the morphologic or immunologic characteristics of the leukaemia.
Expression of PG-M(V3), an Alternatively Spliced Form of PG-M without a Chondroitin Sulfate Attachment Region in Mouse and Human Tissues (1995)

We showed previously that the alternative splicing of chondroitin sulfate attachment domains (CS alpha and CS beta) yielded multiforms of the PG-M core protein in mouse. A transcript encoding a new short form of the core protein PG-M(V3) was found in various mouse tissues using polymerase chain reaction. DNA sequences of the polymerase chain reaction products suggested that PG-M(V3) had no chondroitin sulfate attachment domain. PG-M(V3) was also detected in various human tissues. The presence of a transcript for PG-M(V3) was further supported by Northern blot analysis. Southern blot analysis confirmed that multiforms of the PG-M core protein, including PG-M(V3), were derived from a single genomic locus by an alternative splicing mechanism. Because PG-M(V3) has no chondroitin sulfate attachment region, which is the most distinctive portion of a proteoglycan molecule, this form may have a unique function.
The classification of cyclooxygenase inhibitors. (1998)

In summary, precise classification of COX inhibitors has important clinical implications for efficacy and toxicity. However, classification of these agents clinically is difficult because there are insufficient data to predict correlations between biochemical and pharmacologic properties and the clinical effect of a given agent. In any case, specific COX-2 inhibitors are expected to show antiinflammatory and analgesic activities equivalent to those of NSAID, as well as significant reductions in the incidence of the life threatening side effects (i.e., GI bleeding) associated with COX-1 inhibition. The advantages of preferential COX-2 inhibitors may be more subtle and therefore more difficult to verify in clinical trials.
Quantified assessment of hyperactivity in ADHD youth using IR-UWB radar (2021)

Research on the quantification of hyperactivity in youth with attention-deficit/hyperactivity disorder (ADHD) has been limited and inconsistent. The purpose of this study was to test the discriminative value of impulse-radio ultra-wideband (IR-UWB) radar for monitoring hyperactive individuals with ADHD and healthy controls (HCs). A total of 10 ADHD patients and 15 HCs underwent hyperactivity assessment using IR-UWB radar during a 22-min continuous performance test. We applied functional ANOVA to compare the mean functions of activity level between the 2 groups. We found that the mean function of activity over time was significantly different and that the activity level of the ADHD group slightly increased over time with high dispersion after approximately 7 min, which means that the difference in activity level between the two groups became evident at this period. Further studies with larger sample sizes and longer test times are warranted to investigate the effect of age, sex, and ADHD subtype on activity level function.
Supplementary Table 1 from PD-L1 Expression and Tumor-Infiltrating Lymphocytes Define Different Subsets of MAPK Inhibitor–Treated Melanoma Patients (2023)

&lt;p&gt;Supplementary Table 1. Patterns of PD-L1 staining at various time points of MAPK inhibitor treatment (n=55 PD-L1 positive patients).&lt;/p&gt;
Mobile Computational Photography: Exposure Fusion on the Nokia N900 (2021)

This paper explores the Nokia N900 platform as a versatile playground for mobile computational photography. We present the implementation of a simple yet practical application to acquire high quality tone mapped HDR images, and a relatively straightforward white balance selection. We have built everything from scratch: from the capture of the bracketed sequence of images with different exposures, to the final tone mapping algorithm. Completed in less than one week, showcasing the flexibility and productivity of the platform, our experiments have encouraged us to continue exploring all the possibilities this kind of devices offer.