gebhart/patrepeval huggingface dataset:
MetaWBC: POSIX-Compliant Metadata Write-Back Caching for Distributed File Systems (2022)

In parallel and distributed file systems, caching can improve data performance and metadata operations. Currently, most distributed file systems adopt a write-back data cache for performance and a write-through metadata cache for simplifying consistency. However, with modern file systems scales and workloads, write-through metadata caching can impact overall file system performance, e.g., through lock contention and heavy RPC loads required for namespace synchronization and transaction serialization. This paper proposes a novel metadata write-back caching (MetaWBC) mechanism to improve the performance of metadata operations in distributed environments. To achieve extreme metadata performance, we developed a fast, lightweight, and POSIXcompatible memory file system as a metadata cache. Further, we designed a file caching state machine and included other performance optimizations. We coupled MetaWbc with Lustre and evaluated that MetaWbc can outperform the native parallel file system by up to 8x for metadata-intensive benchmarks, and up to 7x for realistic workloads in throughput.
Peritoneal Dialysis Fluid Induces P38-Dependent Inflammation in Human Mesothelial Cells (2010)

These data confirm concordant p38-dependent upregulation of IL-8 and HSP70 following exposure to bioincompatible PDF. The MAPK p38 pathway therefore links proinflammatory processes and the cellular stress response in human peritoneal mesothelial cells.
Is a picture worth a thousand (forgotten) words?: neuroimaging evidence for the cognitive deficits in âchemo-fogâ/âchemo-brainâ (2009)

The diminution in cognitive function reported to occur in patients treated with adjuvant cancer chemotherapy (a phenomenon known as 'chemo-fog, 'chemo-brain' or similar designation) is supported with varying degrees of evidence by prospective and retrospective clinical studies. However, the cognitive deficits are often subtle and the methodologies used to measure them not consistent. Additionally, patients might be able to compensate for the deficits, thereby leading to underestimates of the problem by this type of assessment. For these reasons, direct neuroimaging techniques might provide additional insight. The relatively few such studies, and fewer electrophysiological studies, offer an alternative way to evaluate changes that might be related to cognitive deficits in patients treated with cancer chemotherapeutic regimens.
Quantitative Evaluation on the Evolution of Water Cone Behavior in a Heavy Oil Reservoir With Bottom Water (2019)

Abstract In order to solve the problem of the unclear understanding of the water cone behavior and its influencing factors of horizontal well in a heavy oil reservoir with bottom water, in this paper, a series of physical models were established to quantitatively describe the inner relationships between them and further illustrated their influence on the water-cut increasing law. The results showed that the water cone and water-cut grew quickly in the heavy oil reservoir with bottom water. The sweep efficiency of the basic 2D sand-pack model reaches 0.68. The decrement of crude oil viscosity increases the sweep efficiency to about 0.08. The increment of production pressure drop increases the sweep efficiency to about 0.05–0.07. Heterogeneity enhancement decreases the sweep efficiency to about 0.06. The addition of adjustment well and barriers increases the sweep efficiency to about 0.20 and 0.08, respectively. The final sweep efficiency of the whole water cone in the 3D sand-pack model reaches 0.42. Finally, we found that the water-cut increment rules are mainly affected by water cone behavior, production schedule, and the location and distribution of barriers. The study in this paper lays a foundation for the rational and effective development of heavy oil reservoirs with bottom water, which has a broad field application prospects in the future.
An improvement of steganography scheme based on complete complementary codes (2012)

Information hiding scheme using direct sequence spread spectrum (DS-SS) technique is one of the effective ways to embed secret information into media contents securely. In recent years, information hiding schemes based on complete complementary codes have been proposed. In particular, it has been shown that it is possible to embed a large message into an image by a blind steganography scheme based on complete complementary codes. However, it has been pointed out that bit errors occur since the source image is not referred to by the blind scheme. In this paper, we apply low-density parity-check (LDPC) codes to the steganography scheme and analyze the bit error rate (BER) performance by numerical experiments.
Internet.Pajama (2005)

Internet.Pajama is a novel application aimed at promoting physical closeness in remote communication between parents and children. A special pajama suit which is able to reproduce a hugging sensation is developed for the child. Parent is able to hug and physically interact with child by hugging a doll. Both pajama and doll are connected wirelessly through the Internet. The pajama also changes color and temperature according to how far away parent is from child.
A 130 nm CMOS Receiver for Visible Light Communication (2022)

Visible light communication (VLC) is an emerging technology that has been gaining attention over the last few years. Transmission of data at higher rates in a VLC system is mainly limited by the modulation bandwidth of the employed LED. To alleviate this limitation, equalization is frequently employed. This is usually achieved by either using discrete circuit elements or in digital form. In this paper, we present a power-efficient VLC receiver as a system-on-chip, implemented in 130 nm CMOS technology. The proposed receiver supports LEDs with different bandwidths thanks to the switchable equalizer. We tested the proposed receiver using phosphorescent white LEDs with different bandwidths on an experimental VLC link. For each tested LED, around 20 fold improvement in data rate was achieved compared to the original bandwidth of the LED. For the LED with a modulation bandwidth of 1.6 MHz, data rates of 32 Mbps and 50 Mbps at a BER of <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"><tex-math notation="LaTeX">$10^{-2}$</tex-math></inline-formula> were obtained at a distance of 2 meters without and with a blue filter, respectively.
Desiccation Tolerance of Spermatozoa Dried at Ambient Temperature: Production of Fetal Mice1 (2003)

Long-term preservation of mouse sperm by desiccation is economically and logistically attractive. The current investigation is a feasibility study of the preservation of mouse sperm by convective drying in an inert gas (nitrogen). Mouse sperm from the B6D2F1 strain isolated in an EGTA-supplemented Tris-HCl buffer were dried using three different drying rates and were stored for 18-24 h at 4 degrees C. The mean final moisture content was <5% for all the protocols. After intracytoplasmic sperm injection (ICSI), the mean blastocyst formation rates were 64%, 58%, and 35% using the rapid-, moderate-, and slow-drying protocols, respectively. The slow-drying protocol resulted in a rate of development significantly lower than that observed using rapid- and moderate-drying protocols and indicated that a slower drying rate may be detrimental to the DNA integrity of mouse sperm. The transfer of 85 two- or four-cell embryos that were produced using rapidly desiccated sperm resulted in 11 fetuses (13%) on Day 15 compared with the production of 34 fetuses (40%) produced using the transfer of 86 two- or four-cell embryos that were produced using fresh sperm (P < 0.05). The results demonstrate the feasibility of using a convective drying protocol for the successful desiccation of mouse sperm and identifies some of the important parameters required for optimization of the procedure.
Extracting Semantics from Maintenance Records (2021)

Rapid progress in natural language processing has led to its utilization in a variety of industrial and enterprise settings, including in its use for information extraction, specifically named entity recognition and relation extraction, from documents such as engineering manuals and field maintenance reports. While named entity recognition is a well-studied problem, existing state-of-the-art approaches require large labelled datasets which are hard to acquire for sensitive data such as maintenance records. Further, industrial domain experts tend to distrust results from black box machine learning models, especially when the extracted information is used in downstream predictive maintenance analytics. We overcome these challenges by developing three approaches built on the foundation of domain expert knowledge captured in dictionaries and ontologies. We develop a syntactic and semantic rules-based approach and an approach leveraging a pre-trained language model, fine-tuned for a question-answering task on top of our base dictionary lookup to extract entities of interest from maintenance records. We also develop a preliminary ontology to represent and capture the semantics of maintenance records. Our evaluations on a real-world aviation maintenance records dataset show promising results and help identify challenges specific to named entity recognition in the context of noisy industrial data.
The Stock Performance of American Companies Investing in a Culture of Health (2019)

This study supports the view that employers' efforts to build an internal culture of health is a sound business strategy. More research is needed, however, to establish whether a link exists between supporting healthy community initiatives and company stock performance.
Recalcitrant lip verrucous carcinoma successfully treated with acitretin after carbon dioxide laser ablation (2018)

Verrucous carcinoma is a rare variant of well-differentiated squamous cell carcinoma with locally aggressive and minimal metastatic potential.1 Oral verrucous carcinoma (OVC) is the most common type of verrucous carcinoma in the head and neck regions and accounts for 55.9% of 2350 such cases.1 The overall 5-year survival rate for OVC is approximately 50% in a retrospective cohort study.2 The risk factors for OVC include chronic inflammation induced by chemical carcinogenesis associated with betel quid chewing, smoking, human papillomavirus infection, and immunosuppression.
Modern Metal-on-Metal Hip Resurfacing: Important Observations from the First Ten Years (2008)

1Center for Joint Preservation and Replacement, Rubin Institute for Advanced Orthopaedics, Sinai Hospital of Baltimore, 2401 West Belvedere Avenue, Baltimore, MD 21215. E-mail address: [email protected] 2Joint Replacement Institute, 2200 West Third Street, Suite 400, Los Angeles, CA 90057
Der Cortex oder die Großhirnrinde (2019)

Der kleine Gehirnversteher reißt die Sprachbarriere ein, die die Hirnforschung zwischen uns und unserem Gehirn errichtet hat. Jedes der fünfunddreißig kurzen, erhellenden und unterhaltsamen Kapitel erklärt einen grundlegenden Begriff der Hirnforschung anhand einer ungewöhnlichen Geschichte. Leicht zu lesen, vollständig und extrem lehrreich: das erste Buch, das den Leser zum Gehirnversteher macht.
Better allele-level matching improves transplant-related mortality after double cord blood transplantation (2015)

Cord blood transplant requires less stringent human leukocyte antigen matching than unrelated donors. In 133 patients with hematologic malignancies who engrafted after double cord blood transplantation with a dominant unit, we studied the effect of high resolution testing at 4 loci (-A, -B, -C, -DRB1) for its impact on 2-year transplant-related mortality. Ten percent of the dominant cord blood units were matched at 7-8/8 alleles using HLA-A, -B, -C, and -DRB1; 25% were matched at 6/8, 40% at 5/8, and 25% at 4/8 or less allele. High resolution typing at 4 loci showed that there was no 2-year transplant-related mortality in 7-8/8 matched patients. Patients with 5-6/8 matched dominant cord blood units had 2-year transplant-related mortality of 39% while patients with 4/8 or less matched units had 60%. Multivariate regression analyses confirmed the independent effect of high resolution typing on the outcome when adjusted for age, diagnosis, CD34(+) cell dose infused, graft manipulation and cord to cord matching. The worst prognostic group included patients aged over 32 years with 4/8 or less matched cord blood units compared with patients who were either younger than 32 years old independent of allele-level matching, or aged over 32 years but with 5-6/8 matched cord blood units (Hazard Ratio 2.2; 95% confidence interval: 1.3-3.7; P<0.001). Patients with 7-8/8 matched units remained the group with the best prognosis. Our data suggest that high resolution typing at 4 loci and selecting cord blood units matched at at least 5/8 alleles may reduce transplant-related mortality after double cord blood transplantation.
Preparation of<i><scp>N</scp></i>‐Sulfinyl Aldimines Using Pyrrolidine as Catalyst<i><scp>via</scp></i>Iminium Ion Activation (2018)

Abstract A procedure yielding N ‐benzylidene‐ p ‐toluenesulfinamide ( 1 ) as a white crystalline solid is presented. A one‐necked round‐bottomed flask with a Teflon‐coated magnetic stir bar is connected to a reflux condenser fitted with a calcium sulfate‐filled drying tube. Notes on the paraphernalia and chemicals to be used are provided after the procedure. The chapter concludes with a brief discussion on N ‐Sulfinyl imines 4 as intermediates for the synthesis of a wide range of nitrogen‐containing molecules.
Investigation on particle mixing characteristics of municipal solid wastes fluidized bed incinerator (2001)

A municipal solid waste (MSW) incinerator with different density fluidized bed was developed by Zhejiang University. The long size, incombustible heavy materials take about 20 percent of the MSW feeding into the incinerator in weight. These incombustible materials cause fluidization trouble. so a special fluidized bed with inclined air distributor and directional air nozzle was developed to rapidly remove these incombustible materials from the incinerator. This paper deals with research on the particle mixing characteristic of this MSW fluidized bed incinerator, the experimental results show that the bed height change doesn't influence the critical fluidization velocity, in the condition of the traditional horizontal air distributor, the directional air nozzle can improve the movement of heavy materials, and the inclined air distributor enhance the effect, the application of both two method can help rapidly remove the heavy materials feeding into the incinerator, the experimental results of which can be of practical value for improving design of the MSW fluidized bed incinerator.
Network Processors: A Practical Approach for Achieving Wire-Speed Packet Processing in the Emerging Optical Backbone Networks (2007)

In this paper, the wire-speed packet processing issue is studied for optical packet/burst switching (OPS/OBS) switching nodes as well as for wavelength-routing (WR) switching nodes. Some assumptions are made to obtain simple estimates of the requirements in terms of forwarding events per second. This is compared with the packet processing performance of electronic devices which implement this type of tasks. Specially, the state-of-the-art in network processor (NP) technology is examined. NPs seem to offer the best flexibility/performance trade-off. Our results reveal that in the OPS/OBS alternatives, wire-speed packet processing cannot be considered a challenge. Furthermore, it is not dependent on the binary rate of packet payload. In wavelength routing networks, the reduction in electronic processing provided by transparent lightpath switching is considered. Nevertheless, this alternative reduces, but does not eliminate, the packet-processing bottleneck. In the authors' opinion this situation will promote OPS/OBS technologies.
Direct observation of two cyclohexenyl (CeNA) ring conformations in duplex DNA (2010)

Cyclohexene Nucleic Acids (CeNA), in which the 2'-deoxyribofuranose ring of the DNA building blocks is substituted by a cyclohexenyl ring, were designed as potential mimics of natural nucleic acids for antisense and, later, for siRNA applications. CeNA units, in contrast to HNA (hexitol nucleic acid) building blocks, show more flexibility at the level of the C2'-C3' bond due to the possibility of the cyclohexenyl moiety to adopt different conformations. In order to analyze the influence of CeNA residues onto the helix conformation and hydration of natural nucleic acid structures and to verify the cyclohexenyl ring conformation, a cyclohexenyl-thymine building block was incorporated into the non-self-complementary sequence d(GCG(xT)GCG)/d(CGCACGC) with (xT) a cyclohexene residue. The crystal structure of this sequence has been determined to a resolution of 1.17 Å and contains two duplexes in the asymmetric unit. The global helices belong to the B-type family and the conformations of the cyclohexenyl rings in both duplexes are different. The cyclohexene ring adopts as well the (2)H(3)-conformation (similar to C2'-endo) as the (3)H(2)-conformation (similar to C3'-endo). The crystal packing is stabilized by cobalt hexamine residues and triplet formation.
Charge control in N-polar InAlN high-electron-mobility transistors grown by plasma-assisted molecular beam epitaxy (2015)

N-polar InAlN-based high-electron-mobility transistors (HEMTs) have fundamental advantages relative to conventional Ga-polar AlGaN HEMTs for high frequency devices. An understanding of the epitaxial design space for controlling sheet carrier density (ns) and mobility (μ) is desirable to maximize power and frequency performance by improving breakdown voltage and reducing parasitic access resistance. In this work, the authors show that In0.17Al0.83N barrier thickness has a minimal impact on ns and μ, and an AlGaN cap layer decreases both ns and μ. Optimization of AlN and GaN interlayers can be used to maximize μ and set ns in the range of 1–3 × 1013 cm−2. The authors use this approach to demonstrate N-polar HEMTs grown on freestanding GaN substrates with sheet resistance Rs = 190 Ω/◻ and μ = 1400 cm2/V·s, leading to a maximum drain current density of 1.5 A/mm for HEMTs with a 5-μm source–drain spacing and Pt-based Schottky gates.
Characterization of UV laser ablation for microprocessing of a-Si:H thin films (2006)

Hydrogenated amorphous silicon has been widely studied last years, both from the basic research and industrial points of view, due to the important set of potential applications that this material offers, ranging from Thin Films Transistors (TFTs) to solar cells technologies. In different fabrication steps of a-Si:H based devices, laser sources have been used as appropriate tools for cutting, crystallising, contacting, patterning, etc., and more recent research lines are undertaking the problem of a-Si:H selective laser ablation for different applications. The controlled ablation of photovoltaic materials with minimum debris and small heat affected zone with low processing costs, is one of the main difficulties for the successful implementation of laser micromachining as competitive technology in this field. This work presents a detailed study of a-Si:H laser ablation in the ns regime. Ablation curves are measured and fluence thresholds are determined. Additionally, and due to the improved performance in optolectronic properties associated to the nanocrystalline silicon (nc-Si:H), some samples of this material have been also studied.
Near vision contrast sensitivity after photorefractive keratectomy (1997)

These preliminary results indicate that Snellen visual acuity and near contrast sensitivity returned to baseline within 1 year after PRK.
Synthesis and refolding of human TIMP‐2 from <i>E. coli</i>, with specific activity for MMP‐2 (1995)

Tissue inhibitors of metalloproteinase (TIMPs) are inhibitory counterparts of collagenases, containing 12 cysteine residues paired to six internal disulphide bridges. TIMP-2, an inhibitory protein of 72 kDa gelatinase/type IV collagenase (MMP-2), was expressed in Escherichia coli as a fusion protein with a 34 amino acid NH2-linked tail containing six consecutive histidine residues. The protein was purified in a single-step using an ion metal affinity column (IMAC) in denaturing conditions. The immobilized fusion TIMP-2 protein was refolded at a high concentration in the column, producing about 5 mg of protein per litre of bacterial cells. It shows specific binding and inhibitory activity against MMP-2, but has no effect against 92 and 45 kDa gelatinases.
Imaging Local Dielectric and Mechanical Responses with Dynamic Heterodyned Electrostatic Force Microscopy (2005)

A scanning probe microscopy based technique has been developed for mapping variations in the polarizability of materials. A number of experiments illustrating the potential of this technique are presented. These include the image of a grating sample with alternating regions of materials with different dielectric constants. Next, the technique is used to study mechanical resonances and dynamics in microelectromechanical (MEM) structures. Finally, a stroboscopic image of an operating 434 MHz surface acoustic wave device shows that the instrument can detect dipoles at frequencies four orders of magnitude of the resonance frequency of the sensing cantilever. In this experiment the dipoles imaged result from the mechanical action of the surface acoustic wave on the piezoelectric substrate. The technique may be employed to produce images that display the local polarizability of materials as a function of frequency and we expect this technique to be useable at frequencies into the millimeter wave region.
Study on Flow Induced Vibration of Head Disk Assembly Mechanisms in Actual Hard Disk Drives (2006)

It is important to clarify air flow induced bibration characteristics in hard disk drives in order to achieve ultra-high magnetic recording density. We studied flow induced flutter vibration in actual 2.5 inch HDD which has one disk and two magnetic heads. In this study, the disk flutter vibration as well as static pressure distribution between the top cover and disk were measured, changing the track following and seek modes of the magnetic head slider. From the experimental results, it was found that the disk flutter amplitude increases and its frequency decreases, when the magnetic head is operating on a disk. We also found that the mean pressure distribution was changed under various head operating conditions. As a result, it suggests that a disk flutter amplitude increase is due to the change of mean pressure distributions and disk flutter frequency decrease is caused by the effect of head-disk coupling vibration system.
ChemInform Abstract: A TOTAL SYNTHESIS OF RESERPINE (1980)

Abstract Ausgehend von der Dihydrobenzoesäure (I) wird zunächst das Olefin (IV) dargestellt, aus dem durch Umsetzung mit dem Pseudosäure‐bromid von cis‐β‐Acetyl‐acrylsäure in Gegenwart von Ag2O/CaSO4 das Ketal (V) gewonnen werden kann.
Двойное слепое, рандомизированное исследование, направленное на сравнение арипипразола и оланзапина у пациентов с шизофренией (2009)

Background: Few studies have directly compared the efficacy and tolerability of atypical agents. Methods: This multicenter, randomized, double-blind study compared the efficacy and tolerability of aripiprazole (n=355) with olanzapine (n=348) in patients with schizophrenia experiencing acute relapse. After a 6-week acute treatment phase, patients with Clinical Global Impression-Improvement =1-3 or ≥20% reduction in the Positive and Negative Symptom Scale (PANSS) Total score could progress to the 46-week outpatient extension phase. Co-primary study objectives were to compare efficacy at Week 6 and weight gain liability from baseline to Week 26. Results: The mean olanzapine dose was 15.4 mg/day compared with a mean aripiprazole dose of 23.0 mg/day. More patients treated with olanzapine (47%) completed the 52-week study than those treated with aripiprazole (39%); time to discontinuation was significantly in favor of olanzapine (p