gebhart/patrepeval huggingface dataset:
1926–2016: 90 Years of listeriology (2016)

ISOPOL - for "International Symposium on Problems of Listeria and Listeriosis" - meetings gather every three years since 1957 participants from all over the world and allow exchange and update on a wide array of topics concerning Listeria and listeriosis, ranging from epidemiology, diagnostic and typing methods, to genomics, post-genomics, fundamental microbiology, cell biology and pathogenesis. The XIXth ISOPOL meeting took place in Paris from June 14th to 17th, 2016 at Institut Pasteur. We provide here a report of the talks that were given during the meeting, which represents an up-to-date overview of ongoing research on this important pathogen and biological model.
Phytotoxicity of uncomposted and composted poultry manure. (2010)

Different uncomposted and composted poultry manure types (laying hen and broiler), mixed at increasing rates (0, 25, 50, 75 and 100%) with two amended peat substrates, were tested to study the phytotoxicity using the cress ( Lepidium sativum, L. ) germination method. The results showed that composting generally reduced the phytotoxicity of the manure mixtures. The germination index was highest in both amended peat substrates. When the peat substrates were mixed with uncomposted poultry manure, only the rate of 25% of uncomposted poultry manure from laying hens showed reduced toxicity. These was not phytotoxicity when the poultry manure was composted in rates of 25, 50 and 75% of deep-pit manure from laying hens and in rates of 25 - 50% of the poultry manures from stock piled, deep litter and broiler litter in mixtures with both peat substrates.
High Density Ti6Al4V via Slim Processing: Microstructure and Mechanical Properties (2011)

This paper investigates a density improvement method for Ti6Al4V alloy processed by the selective laser melting method. A modified inert gas inlet baffle has been employed to develop improved mechanical properties for these materials. Comparisons of the top surface and cross-section porosities of solid blocks processed by the original and modified gas inlet baffles indicate that the modified baffle greatly increases the properties of the processing blocks. Results showed that the porosity of the Ti6Al4V alloy was lower than 0.1% by area. The microstructure of the SLM Ti6Al4V alloy exhibited martensitic α' phase. The UTS tensile strength was 920-960MPa and the elongation at the fracture was 3-5%. The fracture surfaces of the tensile samples demonstrated a mixture of ductile and brittle fracture.
Counterion Dependent Structural Diversity in Silver Polyselenides; Structures of the New Complex Anions [Ag(Se<sub>4</sub>)], [Ag(Se<sub>5</sub>)] and [Ag<sub>4</sub>(Se<sub>4</sub>)<sub>3</sub>]<sup>2⊖</sup> (1989)

Large cations such as Ph4P⊕ and Pr4N⊕ favor a trigonal planar coordination, small ones such as Me4N⊕ a tetrahedral coordination of Ag⊕ in silver polyselenides. In the novel complex {[Me4N][Ag(Se5)]}n one-dimensional infinite [Ag(Se5)] macroanions are present in which the Se ligands bridge three Ag atoms (see 1).
High Power thin disk Yb:YAG regenerative amplifier (2001)

The amplification of ultra short pulses to an energy of 1 mJ at a repetition rate of 10 kHz and a pulse length of 5 ps has been demonstrated with a diode-pumped thin disk Yb:YAG regenerative amplifier without pulse stretching and compression. At a lower repetition rate of 1 kHz, pulse energies of 4.5 mJ have been obtained. A similar system based on Nd:YVO4 with slightly longer pulses has also been investigated.
Energy Efficient Scheduling of Real Time Signal Processing Applications through Combined DVFS and DPM (2016)

This paper proposes a framework to design energy efficient signal processing systems. The energy efficiency is provided by combining Dynamic Frequency and Voltage Scaling (DVFS) and Dynamic Power Management (DPM). The framework is based on Synchronous Dataflow (SDF) modeling of signal processing applications. A transformation to a single rate form is performed to expose the application parallelism. An automated scheduling is then performed, minimizing the constraint of energy efficiency and providing DVFS and DPM decisions. This framework uses an architecture model including the number of available cores, the per-actor processing load and the energy per-cycle, derived from time and power measurements of modelled applications. After introducing the proposed framework, the energy characterization of big.LITTLE SoC systems is described. A generic approach is presented to generate the energy model of a platform from power measurements as customized polynomials. Finally, the experimental results on a Samsung Exynos 5410 big.LITTLE processor show that the energy optimal execution is not obtained by Linux governors that can execute either as-fast-as-possible or as-slow-as-possible. Instead, the most energy efficient scheduling is obtained by adapting both DVFS and DPM to application needs.
Inhibition of plasminogen activator inhibitor-1 is a potential therapeutic strategy in ovarian cancer (2015)

Plasminogen activator inhibitor (PAI)-1 is predictive of poor outcome in several types of cancer. The present study investigated the biological role for PAI-1 in ovarian cancer and potential of targeted pharmacotherapeutics. In patients with ovarian cancer, PAI-1 mRNA expression in tumor tissues was positively correlated with poor prognosis. To determine the role of PAI-1 in cell proliferation in ovarian cancer, the effects of PAI-1 inhibition were examined in PAI-1-expressing ovarian cancer cells. PAI-1 knockdown by small interfering RNA resulted in significant suppression of cell growth accompanied with G2/M cell cycle arrest and intrinsic apoptosis. Similarly, treatment with the small molecule PAI-1 inhibitor TM5275 effectively blocked cell proliferation of ovarian cancer cells that highly express PAI-1. Together these results suggest that PAI-1 promotes cell growth in ovarian cancer. Interestingly, expression of PAI-1 was increased in ovarian clear cell carcinoma compared with that in serous tumors. Our results suggest that PAI-1 inhibition promotes cell cycle arrest and apoptosis in ovarian cancer and that PAI-1 inhibitors potentially represent a novel class of anti-tumor agents.
The laboratory simulation of thermal shock failure (1996)

Infrared transparent windows on aircraft and missiles can be subjected to rapid heating which can cause thermal shock failure. A commercially available device for simulating such thermal shock environments has been assessed and used in a study of a range of materials. The material ordering resulting from these experiments has been compared with that obtained by considering a thermal shock figure of merit.
Design Constraints for Mobile, High-Speed Fluorescence Brain Imaging in Awake Animals (2012)

In this paper we present a fully self-contained imaging instrument (30 mm overall length) that is capable of recording high speed and detect relatively small fluorescent signals (0.1% ΔF/F) from brain tissues potentially containing genetically-encoded sensors or dyes. This device potentially enables the study of neuronal activity in awake and mobile animals during natural behaviors without the stress and suppression of anesthesia and restraint. The device is a fully self-contained illumination system, wide field fluorescence microscope (~ 4.8 mm² FOV-25 um lateral resolution-1.8 × magnification-0.39 NA) and CMOS image sensor (32 × 32). The total weight of the system is 10 g and is capable of imaging up to 900 fps. We present voltage dye RH1692 experiments using the system to study the somatosensory cortex of mice during whisker movements using an air puff.
Comparative study of neuronal and glial gap‐junctions in crayfish nerve cords (1989)

Electrical synapses (neuronal gap-junctions) and glial gap-junctions were compared by using thin sectioning, freeze fracturing, and negative staining techniques. Neuronal and glial gap-junctions differed in the length of the extracellular domains of the channels, in the presence of a cytoskeleton associated to neuronal gap-junctions, and in their unit cell dimensions. The difference in length of the channels and the fact that both glial and neuronal gap-junctions had the same particle diameter suggest that the proteins forming glial and neuronal gap-junctions might have different molecular weights. The cytoskeleton associated to neuronal gap-junctions consisted of a beaded layer of densities located parallel to the membrane in the synaptic regions. Synaptic vesicles associated to neuronal gap-junctions were attached to this cytoskeleton, which was in turn anchored to the synaptic membrane through densities about 20 nm apart, a spacing similar to the neuronal unit cell dimension. These results suggest that the cytoskeleton might be responsible for the association of vesicles to neuronal gap-junctions and for maintaining the crystalline appearance of neuronal gap-junctions in situ.
Incidental finding of a giant coronary artery aneurysm of the left anterior descending artery (2013)

An asymptomatic 84-year-old man was referred for cardiology assessment in view of incidental radiology findings. He had coronary artery bypass grafting in 1982 with vein grafts to the right coronary artery and left anterior descending artery (LAD). Angiography in 2000 for recurrent angina demonstrated severe native disease, patent LAD graft and occluded right coronary artery graft. He underwent uncomplicated …
Carriage of extended-spectrum beta-lactamase-producing enterobacteriacae among internal medicine patients in Switzerland (2013)

ESBL-E carriage is endemic amongst internal medicine patients at our institution. We were unable to develop a clinical risk profile to accurately predict ESBL-E carriage amongst these patients.
Two-degree-of-freedom spherical actuator for Omnimobile ROBOT (2003)

This paper deals with the design of a two-degree-of-freedom spherical electrical actuator for mobile robotic applications. It presents the different steps involved in this design, namely the choice of the actuation principle, the modelling of the motor (including the electromechanical) the sizing and the manufacture of a first prototype.
Membrane-associated RING-CH (MARCH) proteins down-regulate cell surface expression of the interleukin-6 receptor alpha chain (IL6Rα) (2019)

Interleukin 6 (IL6) is a cytokine that regulates a number of important immune and inflammatory pathways. We used the ability of IL6 to inhibit the clonal proliferation of the mouse M1 myeloid leukemia cell line in agar to positively screen a cDNA expression library for proteins that inhibited IL6 activity. We found three clones completely resistant to IL6 that contained the cDNA for the Membrane-Associated RING-CH E3 ubiquitin ligase MARCH2. MARCH2 is a member of a family of membrane-bound E3 ubiquitin ligases that target cell surface receptors for degradation. MARCH2 overexpressing M1 clones retained responsiveness to the related cytokines leukemia inhibitory factor and oncostatin M and we showed that its inhibitory effect was a result of selective down-regulation of the IL6 receptor alpha chain and not the shared receptor subunit, gp130 or other signalling molecules. This activity of MARCH2 was also shared with related proteins MARCH4, MARCH9 and an isoform of MARCH3. The transmembrane domains and C-terminal domains, as well as a functional RING domain, of MARCH proteins were all required for substrate recognition and down-regulation. Genetic deletion of individual MARCH proteins in mice had no or little effect on IL6Rα levels but combined deletions of MARCH2,3 and 4 displayed elevated steady-state levels of IL6Rα in selected haemopoietic cell subsets including CD8+ and CD4+ T cells. These studies extend the potential immunosuppressive roles of MARCH proteins to include down-regulation of IL6 inflammatory responses.
STUDIES ON PLANT BILE PIGMENTS—9. PHOTOOXIDATION OF A-DIHYDROBILINDIONE AS PHYTOCHROME MODEL IN ACID MEDIUM (1981)

— The photooxidation of octaethyl-2, 3-dihydrobilindione (2) as a model for the Pr-chromophore has been studied in acidic methanol. When 2 is titrated with HCl to the cation and irradiated under N2 with an excess of I2, violin and rhodin type pigments are formed bearing methoxy-substituents at either C-4,5 or C-15,16, respectively. The reaction is slowed down as compared to neutral conditions, it is no longer regioselective at the C-5 methine bridge, and the formation of dimers is suppressed. From the data of this and earlier chemical model studies on the photooxidation of 2, and the known properties of phytochrome, a reaction for the Pr Pfr phototransformation is suggested, in which the chromophore is attacked by the protein moiety in a sequence of oxidation and nucleophilic substitution, which may lead to a primary redox signal for the physiological response.
Photografting and patterning of oligonucleotides on benzophenone-modified boron-doped diamond (2007)

Irradiation of a patterned benzophenone-terminated boron-doped diamond (BDD) surface with UV light (lambda = 350 nm) in the presence of a 15(mer) oligonucleotide resulted in the covalent linking of the DNA strand to the BDD interface.
Microwave-modulated transmitter design for hybrid LIDAR-RADAR (2002)

The application of well-established, coherent RADAR technology to aerial light detecting and ranging (LIDAR) systems has reduced incoherent backscatter clutter by 17 dB in laboratory experiments and computer simulations. The full-scale experimental realization of this hybrid LIDAR-RADAR system is hampered by the unavailability of a stable modulation source capable of providing high peak powers to overcome the large dynamic range required for the LIDAR backscatter measurement. Two methods being investigated for the microwave-modulation of a transmitted optical pulse to be utilized in the actual LIDAR environment are detailed.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Separable cooperative and localized translational motions of water confined by a chemically heterogeneous environment (2007)

We report quasi-elastic neutron scattering experiments at two resolutions that probe timescales of picoseconds to nanoseconds for the hydration dynamics of water, confined in a concentrated solution of N-acetyl-leucine-methylamide (NALMA) peptides in water over a temperature range of 248 K to 288 K. The two QENS resolutions used allow for a clean separation of two observable translational components, and ultimately two very different relaxation processes, that become evident when analyzed under a combination of the jump diffusion model and the relaxation cage model. The first translational motion is a localized beta-relaxation process of the bound surface water, and exhibits an Arrhenius temperature dependence and a large activation energy of approximately 8 kcal mol(-1). The second non-Arrhenius translational component is a dynamical signature of the alpha-relaxation of more fluid water, exhibiting a glass transition temperature of approximately 116 K when fit to the Volger Fulcher Tamman functional form. These peptide solutions provide a novel experimental system for examining confinement in order to understand the dynamical transition in bulk supercooled water by removing the unwanted interface of the confining material on water dynamics.
Femoroacetabular Impingement: Defining the Condition and its Role in the Pathophysiology of Osteoarthritis (2013)

Femoroacetabular impingement (FAI) is an increasingly recognized cause of hip pain. It is best defined as a pathologic mechanical process by which morphologic abnormalities of the acetabulum and/or femur combined with vigorous hip motion lead to repetitive collisions that damage the soft-tissue structures within the joint itself. Based on cross-sectional studies in which FAI morphology was studied before the presence of radiographic osteoarthritis (OA), and on prevalence studies in younger, asymptomatic persons, it is clear that FAI and its morphologic risk factors are common in young adult hips and predispose to the later development of OA in certain patients. Longitudinal studies also support the assertion that, in middle-aged adults, the presence of cam deformities at baseline substantially increases the risk of developing OA and the need for total hip arthroplasty. More longterm data are needed to better define the natural history of pincer deformities as well as FAI in younger cohorts.
The effect of increased background resistance on the resistive load threshold for eliciting the respiratory-related evoked potential (2007)

The detection threshold (DeltaR(50)) of resistive (R) loads is a function of the total background resistance (R(0)). Increased R(0) increases the DeltaR(50), but the ratio DeltaR(50)/R(0) remains constant. The respiratory-related evoked potential (RREP) is elicited only by R loads greater than the cognitive detection threshold, DeltaR(50). We hypothesized that the RREP Nf, P1, and N1 peaks will be elicited only when the added load DeltaR/R(0) is greater than the normal detection threshold, DeltaR(50)/R(0) = 0.30. We also hypothesized that when the R(0) is increased by adding extrinsic R, the RREP will not be elicited if the DeltaR/R(0) is less than the 0.30 ratio. RREPs were recorded with healthy volunteers (n = 20) respiring through a non-rebreathing valve. Three inspiratory R loads that spanned the DeltaR(50)/R(0) = 0.30 detection threshold were presented in two conditions: 1) no added R(0) (R1 < 0.30, R2 > 0.30, R3 > 0.30); and 2) increased R(0) = 13.3 cmH(2)O.l(-1).s (R1 < 0.30, R2 < 0.30, R3 > 0.30). For the control R(0), P1, Nf, and N1 peaks of the RREP were elicited by both R2 and R3, and not present with R1. The increased R(0) decreased R2/R(0) > 1.5 to R2/R(0) < 0.15. With increased R(0), the R1 and R2 loads did not elicit the RREP, but the Nf, P1, and N1 peaks were present for R3. These results demonstrate that the RREP is present if the DeltaR is above the cognitive detection threshold, and the RREP is absent if the load is below the detection threshold. When the R(0) is increased to make the DeltaR/R(0) less than the detection threshold, the DeltaR no longer elicits the RREP.
Why does the heart rate rise when you see a lady in red? (2004)

Understanding reactions to colour is vital in order to create a stimulating and positive learning environment, reports Paula Hammond.
Hybrid sampling for estimating flow size distribution and its implementation (2010)

Recently, it has been necessary to perform traffic sampling in order to deteriorate the load of capturing and analyzing processes, as the amount of ISP traffic grows. Packet sampling and flow sampling are main sampling techniques. In order to estimate flow size distribution from sampled data, each sampling method has its own advantages and disadvantages. Flow sampling can extract flows in proportion to the original flow size distribution but is difficult to extract large-sized flows due to the heavy-tailed flow size distribution. On the other hand, packet sampling can extract large-sized flows but complete flows cannot be extracted. In this paper, we propose a hybrid sampling method which performs both flow sampling and packet sampling in parallel to utilize both advantages of above two methods and improve estimation accuracy. We also propose cost-effective implementation which employs a general-purpose switch. By verifying with real traffic data, we confirmed the effectiveness of our proposed method in terms of reproducibility.
Wavelength-Agile Laser Sensors for Measuring Gas Properties in Engines (2003)

&lt;div class="htmlview paragraph"&gt;Internal combustion engines present a harsh environment for optical sensors, owing to challenges such as high pressures, multiple phases, and window fouling. Fortunately, a new class of “wavelength-agile” light sources that rapidly scan through a broad wavelength range facilitates accurate absorption spectroscopy in engines. Gas temperature and species concentrations can be monitored with fast time response (down to ∼ 1 μs). Here, two strategies for generating wavelength-agile light are introduced. We present in-cylinder results obtained by applying one of the strategies to monitor gas temperature and H&lt;sub&gt;2&lt;/sub&gt;O concentration during compression in a single-cylinder optical engine operating in HCCI mode. Such data will be useful for improving the understanding of engine phenomena and offer the potential for active engine control.&lt;/div&gt;
Mass spectrometry (1986)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTMass spectrometryA. L. Burlingame, Thomas A. Baillie, and Peter J. DerrickCite this: Anal. Chem. 1986, 58, 5, 165–211Publication Date (Print):April 1, 1986Publication History Published online1 May 2002Published inissue 1 April 1986https://pubs.acs.org/doi/10.1021/ac00296a015https://doi.org/10.1021/ac00296a015research-articleACS PublicationsRequest reuse permissionsArticle Views859Altmetric-Citations59LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
A Bayesian approach for the estimation and transmission of regularization parameters for reducing blocking artifacts (2000)

With block-based compression approaches for both still images and sequences of images annoying blocking artifacts are exhibited, primarily at high compression ratios. They are due to the independent processing (quantization) of the block transformed values of the intensity or the displaced frame difference. We propose the application of the hierarchical Bayesian paradigm to the reconstruction of block discrete cosine transform (BDCT) compressed images and the estimation of the required parameters. We derive expressions for the iterative evaluation of these parameters applying the evidence analysis within the hierarchical Bayesian paradigm. The proposed method allows for the combination of parameters estimated at the coder and decoder. The performance of the proposed algorithms is demonstrated experimentally.