gebhart/patrepeval huggingface dataset:
Exponential assembly (2001)

A replicative assembly methodology may be based on assembly stations, each with two degrees of rotational freedom. These stations share translational degrees of freedom in the three Cartesian axes by using a common translating mechanism. The methodology provides replication of the assembly stations, but due to the common translating mechanism and control systems, it cannot be termed self-replicating. The term `exponential assembly' is proposed to differentiate this from self-replication. The exponential assembly architecture can use parts made from many manufacturing methods, provided that parts of considerable complexity can be produced. Because integrated circuit manufacturing methods used for micro-electromechanical systems allow large numbers of complex components to be produced, it is one possible method for pursuing such an approach to manufacturing. The methodology is scalable and therefore useful for producing assembly stations which might in turn produce other devices at ever-decreasing length scales as part of a top-down approach to nanotechnology.
Properties of iron under Earth’s core conditions: Molecular dynamics simulation with an embedded-atom method potential (2008)

Using an earlier proposed embedded-atom method potential, we have performed molecular dynamics simulations of the thermodynamic, structural, and diffusional properties of iron under Earth’s core conditions (temperatures of up to 5000 K and densities of up to 12.5 g/cm3). The results attest to spontaneous crystallization of liquid iron at certain parameters of state. We have derived equations of state for the liquid and solid phases and have calculated their heat capacities at constant pressure and temperature, thermal expansion coefficients, isothermal and adiabatic bulk moduli, and sound velocities under various conditions. In addition, we have calculated the heat of fusion of iron and the change in its molar volume on melting. The results agree with literature data. The self-diffusion coefficient of iron decreases linearly with increasing density, vanishes at the densities corresponding to the liquid-solid phase boundary, and is a roughly linear function of temperature.
Engine testing of ceramic cam-roller followers (1992)

For several years, DDC has been developing monolithic ceramic heat engine components. One of the components, developed for an application in our state-of-the-art on-highway, heavy-duty diesel engine, the Series 60, is a silicon nitride cam-roller follower. Prior to starting this program, each valve train component in the Series 60 was considered for conversion to a ceramic material. Many advantages and disadvantages (benefits and risks) were considered. From this effort, one component was selected, the cam-roller follower. Using a system design approach, a ceramic cam-roller follower offered functional improvement at a reasonable cost. The purpose of the project was to inspect and test 100 domestically produced silicon nitride cam-roller followers built to the requirements of the DDC series 60 engine.
PaIntDB: network-based omics integration and visualization using protein–protein interactions in <i>Pseudomonas aeruginosa</i> (2021)

Supplementary data are available at Bioinformatics online.
Short 17-cm DBR Raman Fiber Laser With a Narrow Spectrum (2011)

We present experimental results on the lasing of a short distributed Bragg reflector (DBR) Raman fiber laser (RFL) with short cavity length. The high finesse laser cavity with an effective length of 17 cm was realized by direct inscription of two Bragg gratings into a short piece of highly nonlinear polarization maintaining Raman fiber. It is pumped by an Ytterbium fiber laser at 1100 nm with up to 8 W pump power. The Stokes wave at 1151 nm is generated within the DBR RFL with 700-mW output power and a narrow spectral full-width at half-maximum bandwidth of 60 pm. Due to the short cavity length, the number of oscillating longitudinal modes is strongly reduced to less than 24 modes. The short DBR RFL has a low lasing threshold of 4.1 W. Its spectral properties and temporal stability are investigated. Distinct longitudinal cavity modes could be observed within the radio-frequency intermode-beat spectrum detected with a fast photodiode. The measured mode separation of 607 MHz validates the short effective length of 17 cm.
Supplemental Figure 3A and 3B from AGS16F Is a Novel Antibody Drug Conjugate Directed against ENPP3 for the Treatment of Renal Cell Carcinoma (2023)

&lt;p&gt;Supplemental Figure 3A. Mapping of AGS16-7.8 binding to different ENNP3 domains. Supplemental Figure 3B. Western blots for mapping recognition of epitopes in ENPP3 ECD fragments.&lt;/p&gt;
The Hospital Zambrano Hellion venous thromboembolism rapid response team (PREVENTION-team): Improving pulmonary embolism and deep venous thrombosis patient care (2020)

to improve proximal DVT and submassive and massive PE patients care. Secondary objectives: Increase diagnosis rate of low-risk PE and distal DVT; exploration of cause; long-term anticoagulation; identify high-risk profile for chronic complications; community-based support groups and patient education to extend the concept of the thrombosis-free hospital to thrombosis-free home. Structure and organization: The team includes cardiologists, vascular medicine, angiologist, echocardiographer, cardiovascular imaging, and interventional cardiologists. The team will be accessible 24 h a day, 7 days a week, 365 days a year, and base on previous national experience. The cardiology fellow on call will be responsible for activation and evaluation. We will design several tools to accelerate these processes. Risk stratification and therapeutic approach will be based on clinical presentation, echocardiogram, and biomarkers findings. According to PERT stratification based on resources and medical specialties, Hospital Zambrano Hellion has level 1 PERT. PREVENTION-team links physicians with different expertise, provide fast, efficient, and time-saving treatment, potentially saving lives and reducing bleeding and chronic complications in VTE patients. Finally, establishing a network in our hospital and health system to improve VTE patients care. To the best of our knowledge, this is the first rapid response team focused on VTE in Mexico.
Editor in chief's message - Following the Ebb and flow at CG&amp;A (2004)

Presents the editorial for this issue of the publication.
Infection of BALB/c mice with the filarial nematode Litomosoides sigmodontis: role of CD4+ T cells in controlling larval development (1997)

Litomosoides sigmodontis is the only filaria which develops from infective larvae into adults in immunocompetent laboratory mice. Depletion of CD4+ T cells from infected BALB/c mice resulted in worm and microfilarial burdens significantly higher than those of infected controls. Th2 cytokines, eosinophilia, and immunoglobulin E, which were strongly induced in infected controls, were diminished in CD4-depleted mice.
The new pegylated interferon beta-1a (sampeginterferon beta-1a, BCD-054) in the treatment of remitting multiple sclerosis (2019)

An integrated analysis of the efficacy, safety, pharmacokinetics, and pharmacodynamics was performed after 20 weeks of study. Mean CUA per scan was lower in the active treatment groups compared to placebo: 0,986±2,046, 0,619±1,055, 0,665±1,165, 1,673±2,376 (groups 1, 2, 3 and placebo group, respectively). The data for CUA per scan demonstrated the superiority of both BCD 054 180 μg and 240 μg over placebo. Patients receiving active treatment had fewer new and/or enlarging lesions after 20 weeks of treatment. The proportion of patients without new T2-weighted lesions was 74,3%, 86,7%, and 78,1% in groups 1, 2, and 3 compared to 64,9% in the placebo group. Manifestations of flu-like syndrome that is expected for interferon treatment were observed with the same incidence in all the active treatment groups. Its severity, duration or the need for symptomatic treatment did not appear to depend on the type of interferon used.
Learning-based Multi-Sieve Co-reference Resolution with Knowledge (2012)

We explore the interplay of knowledge and structure in co-reference resolution. To inject knowledge, we use a state-of-the-art system which cross-links (or “grounds”) expressions in free text to Wikipedia. We explore ways of using the resulting grounding to boost the performance of a state-of-the-art co-reference resolution system. To maximize the utility of the injected knowledge, we deploy a learning-based multi-sieve approach and develop novel entity-based features. Our end system outper-forms the state-of-the-art baseline by 2 B3 F1 points on non-transcript portion of the ACE 2004 dataset. 1
Optimal Power Allocation in Block Fading Channels with Confidential Messages (2015)

International audience
Embedded neuromorphic attention model leveraging a novel low-power heterogeneous platform (2023)

Neuromorphic computing has been identified as an ideal candidate to exploit the potential of event-based cameras, a promising sensor for embedded computer vision. However, state-of-the-art neuromorphic models try to maximize the model performance on large platforms rather than a trade-off between memory requirements and performance. We present the first deployment of an embedded neuromorphic algorithm on Kraken, a low-power RISC-V-based SoC prototype including a neuromorphic spiking neural network (SNN) accelerator. In addition, the model employed in this paper was designed to achieve visual attention detection on event data while minimizing the neuronal populations’ size and the inference latency. Experimental results show that it is possible to achieve saliency detection in event data with a delay of 32ms, maintains classification accuracy of 84.51% and consumes only 3.85mJ per second of processed input data, achieving all of this while processing input data 10 times faster than real-time. This trade-off between decision latency, power consumption, accuracy, and run time significantly outperforms those achieved by previous implementations on CPU and neuromorphic hardware.
Vitamin D and the Innate Immunity (2010)

This chapter will examine the role of vitamin D in the innate immune system as a mediator of human host defense mechanisms against microbial disease, focusing on tuberculosis. The first section will examine tuberculosis and the innate immune response to the intracellular pathogen, Mycobacterium tuberculosis (M. tuberculosis), the causative agent of tuberculosis. This is followed by a discussion of the known associations, genetic and mechanistic, between the vitamin D pathway and tuberculosis susceptibility. Finally, the chapter will conclude with a discussion on the potential for adjuvant treatment of tuberculosis with vitamin D.
Optical coherence tomography imaging after endovascular thrombectomy for basilar artery occlusion: report of 3 cases (2019)

Studies evaluating individuals for endothelial injury after endovascular thrombectomy (EVT) have been done by means of retrieved human thrombus, MR vessel-wall imaging, and animal histopathological studies. These techniques have limitations, because MR imaging has insufficient spatial resolution to directly visualize endothelium, and histopathological examinations are performed ex vivo and are unable to provide real-time patterns of injury. The purpose of the current study was to obtain in vivo intraluminal imaging after EVT by using optical coherence tomography (OCT), examining for evidence of endothelial injury in real time.Three consecutive patients with acute basilar artery occlusion underwent OCT imaging immediately after EVT. There were no complications and adequate images were obtained for all patients. Anatomical features of the vessel wall were discernible, including intima, media, adventitia, and internal/external elastic lamina. Basilar artery thick concentric plaque fibrosis was present, causing outward remodeling and loss of the internal/external lamina in certain regions. Evidence of significant residual thrombus was also visible, with mostly red thrombus present despite complete angiographic revascularization. The residual thrombus was not visible on CT, MR, or cerebral angiography and could certainly cause ongoing function-limiting strokes with occlusion of adjacent vital basilar perforators after EVT.
Fermi-Pasta-Ulam Recurrence in Nonlinear Fiber Optics: The Role of Reversible and Irreversible Losses (2014)

The celebrated Fermi-Pasta-Ulam recurrence phenomenon in nonlinear dynamics was first demonstrated experimentally in optical fibers 50 years after its theoretical discovery. But it was expected to be suppressed when the so-called third-third-order dispersion (TOD) became relevant. A new optical-fiber experiment shows that it not only survives in the presence of TOD, but disappears and reappears several times as the optical pump frequency is varied.
Automated Quantum Entanglement and Cryptography for Networks of Robotic Systems (2021)

Abstract In this paper the procedure for automating the photon quantum experiments for mobile robotic applications is presented. Due to the rapid advances of quantum technologies and quantum engineering, the integration of quantum capabilities in robotic and autonomous systems will be inevitable, and therefore the study and investigation of compatibility and adaptability of quantum systems and classical autonomous systems is of great importance. In a quantum-classical hybrid setup, the source of single photon generation is placed on a leader robot which can send correlated single photons to robot followers. In the case of quantum entanglement, spontaneous parametric down-conversion process using nonlinear paired BBO crystals is implemented which sends entangled photons to the single photon counting modules installed on mobile robots. In the case of quantum cryptography, single photons are sent from Alice robot to Bob robot, where Alice has the course of single photon and Bob has a polarizing beamsplitter and two detectors and that can detect the polarization of photons as vertical and horizontal. Bob then can convert the polarizations to a digital signals as zeros and ones and use them as communication information for control purposes through a classical channel. Motorized optics equipment can automatically align the source of photons to detectors on the mobile robots. The automated alignment procedure is one of the key enabling technologies in integrating quantum capabilities with control of mobile robotic systems. In this paper, in particular, the automated alignment is studied while considering the uncertainties in the dynamic of the system which can potentially cause the alignment task very challenging. The uncertainty analysis in the automated alignment is implemented by Optimal Uncertainty Quantification technique to ensure achieving the quantum control of the robotic systems and presented here for the first time.
Organic Matrix Composites Process-to-Performance, Evaluation, Research and Analysis (OPPERA) (2023)

View Video Presentation: https://doi.org/10.2514/6.2023-2424.vid Reliable bonded composite structures have the potential to improve performance, reduce costs, and increase design flexibility in advanced aircraft systems. One promising robust solution is to use 3D woven textiles that are near-net-shape to connect stiffeners to wing skins. This architecture removes the delamination paths of other joint systems by including fiber tows that are integrally woven through the preform to bind the out-of-plane directions together. Manufacturing and processing variations lead to variability in resin content, residual stresses, and porosity defects, which ultimately influence the strength of the bonded structure. In addition, static and fatigue loading damage progression is not well understood in 3D textiles and there are no validated predictive models. An integrated computational materials engineering (ICME) framework is under development to predict the strength of the bonded structure by integrating models to predict (1) fiber bed compaction, (2) material properties, residual stresses, and porosity evolution during cure, (3) damage evolution at the mesoscale and macroscale, and (4) final part capability. This paper describes an overview of current tools and predictive capabilities.
Influence of Herbicide Safeners on Creeping Bentgrass (<i>Agrostis stolonifera</i>) Tolerance to Herbicides (2015)

Glasshouse research was conducted to investigate the efficacy of herbicide safeners for improving creeping bentgrass (CBG) tolerance to various herbicides. CBG injury from amicarbazone (150 g ha −1 ), bispyribac-sodium (110 g ha −1 ), fenoxaprop-p-ethyl (35 g ha −1 ), imazapic (45 g ha −1 ), quinclorac (1,050 g ha −1 ), or topramezone (37 g ha −1 ) applied in combination with the herbicide safeners naphthalic anhydride or isoxadifen-ethyl was evaluated. These safeners reduced CBG injury from topramezone only. Topramezone was then applied in combination with naphthalic anhydride, isoxadifen-ethyl, cloquintocet-mexyl (cloquintocet), fenchlorazole-ethyl, mefenpyr-diethyl, and benoxacor. These experiments determined that CBG injury was lowest from topramezone in combination with cloquintocet. Additional experiments evaluated topramezone (37 g ha −1 ) with several rates of cloquintocet and determined that applications at ≥ 28 g ha −1 reduced CBG injury similarly. Cloquintocet (28 g ha −1 ) increased topramezone I 50 values against CBG, but not large crabgrass or goosegrass. The cytochrome P450 (cP450) inhibitor malathion (1000 g ha −1 ) reduced topramezone I 50 values against CBG in one experimental run. Topramezone–cloquintocet combinations warrant further research in field settings.
Cryogenic MOSFET kink effect abatement (2008)

The increasing interest in nanoelectronic devices that require cryogenic temperatures to function has lead ?to an increased need for analog CMOS circuits that can perform at these low temperatures. Conventional CMOS transistors, when operated at temperatures at which the majority of carriers experience freeze-out, exhibit an effect known as the kink effect. This occurs when holes generated by avalanche multiplication at the channel-drain interface become trapped in the channel region, causing a lowering of the threshold voltage of the device. We examine two methods of kink effect elimination in n-MOS transistors, one requiring epitaxial growth, and one utilizing retrograde well doping of a bulk substrate. The use of lightly p-doped epitaxial layers of silicon over a substrate of degenerately p-doped silicon to eliminate the kink effect in n-MOS devices was proposed by Broadbent. By providing a negatively biased, degenerately doped substrate that does not succumb to freeze-out we create a path for positively-charged holes to be drawn away from the channel region. We are simulating and fabricating n-MOS transistors to further examine this technique. 1 D-Poisson and 2D SSUPREM simulations have been run for n-MOS transistors fabricated on lightly doped p-epitaxial layers grown on degenerately p-doped silicon substrates. Variations in epitaxial layer thickness and substrate bias are considered. N-MOS transistors with gate lengths of 1.5 ?m to 4 ?m are currently being fabricated on p+ substrates with epitaxial layers ranging from 500 nm to 3 ?m in thickness. These devices utilize a backside contact to provide a variety of negative biases to the body of the n-MOS transistors. A range of bias values will be tested to examine the effect of increased substrate bias on device threshold and kink effect abatement. Fig. 1 shows the band diagram of the nMOS transistors under the gate stack for epitaxial layer thicknesses ranging from 1 ?m to 2.5 ?m. The transistors are shown following the patterning and etching of the polysilicon gate layer.
Diode-pumped intracavity optical parametric oscillator in pulsed and continuous-wave operation (2002)

An intracavity optical parametric oscillator is investigated in pulsed and continuous-wave operation. The intracavity optical parametric oscillator is based on Yb:YAG as the laser material and a periodically poled lithium niobate crystal as the nonlinear material. Tuneable idler output powers above 200 mW are obtained in both modes of operation with 13.5 W of incident diode pump power. The idler output was tuned in the wavelength range 3820-4570 nm.
Role of Cold Balanced Salt Solution (BSS) in the Prophylaxis of Cystoid Macular Edema After Cataract Surgery: A Prospective Randomized Study (2021)

The use of a cooled irrigating eye solution during phacoemulsification may be beneficial in preventing the possible development of postoperative macular thickening. Further clinical studies may support this finding.
The effects of numerical acceleration techniques on PIC-MCC simulations of ion thrusters (2020)

The particle-in-cell-Monte Carlo collision method has been widely used in simulation studies of ion thrusters. Due to the huge computational demand of such simulations, numerical acceleration techniques are required. However, the effects of such numerical acceleration techniques on the simulation results are not clear. In this study, the effects of three numerical acceleration techniques are investigated using a series of simulations that implement different numerical acceleration factors. The resulting plasma potentials, plasma density distributions, and plasma currents in the discharge chamber are compared for simulations accelerated by increasing the vacuum permittivity, reducing the mass of heavy particles, and making use of self-similarity. The results demonstrate that increasing the permittivity thickens the sheath. When the sheath expands enough to extend to the cusps, the distributions of the potentials and the plasma densities are affected, influencing the current parameters. Reducing the masses of heavy particles greatly influences ion properties, especially the plasma density. Thus, it causes significant errors in the potential and current parameters. Errors in the beam current can be significantly decreased by correcting the beam current using an exponent relationship between the mass scaling factor and the plasma density. The use of self-similarity simultaneously thickens the sheath and decreases the particle number density and may slightly reduce the plasma current values. A number of suggestions for employing these techniques are also provided.
Assessment of Different Actuator Concepts for Acoustic Boundary Control of a Premixed Combustor (2008)

In the design process, new burners are generally tested in combustion test rigs. With these experiments, computational fluid dynamics, and finite element calculations, the burners’ performance in the full-scale engine is sought to be predicted. Especially, information about the thermoacoustic behavior and the emissions is very important. As the thermoacoustics strongly depend on the acoustic boundary conditions of the system, it is obvious that test rig conditions should match or be close to those of the full-scale engine. This is, however, generally not the case. Hence, if the combustion process in the test rig is stable at certain operating conditions, it may show unfavorable dynamics at the same conditions in the engine. In a previous paper (GT2007-27796), the authors introduced an active control scheme which is able to mimic almost arbitrary acoustic boundary conditions. Thus, the test rig properties can be tuned to correspond to those of the full-scale engine. The acoustic boundary conditions were manipulated using woofers. In the present study, proportional valves are investigated regarding their capabilities of being used in the control scheme. It is found that the test rig impedance can be tuned equally well. In contrast to the woofers, however, the valves could be used in industrial applications, as they are more robust and exhibit more control authority. Additionally, the control scheme is further developed and used to tune the test rig at discrete frequencies. This exhibits certain advantages compared to the case of control over a broad frequency band.