gebhart/patrepeval huggingface dataset:
TRANSLOCATION OF MRNA CODONS, II. PROPERTIES OF AN ANTI-TRANSLOCASE ANTIBODY (1969)

A purified preparation of translocase, one of several enzymes required for protein biosynthesis, has been used to prepare a specific anti-translocase antibody. This antibody provides an extremely useful tool not only for detecting the enzyme independent of its activity, but for inhibiting the translocase-mediated reaction and, thus, protein biosynthesis. Though the antibody very rapidly inhibits elongation of the peptide chain, it fails to effect initiation, binding, or peptide bond formation, which strongly suggests that translocase is not a direct participant in these reactions. It also arrests translation of the defined tricodon AUG(U(6)) at the second codon, permitting formation only of the dipeptide, fMet-Phe, rather than the tripeptide, fMetPhe-(Phe)(2), which is formed in the presence of control serum. We have shown previously that the third codon becomes available only in the presence of translocase, thereby defining the site of action of the antibody. The antibody also has been used to demonstrate that translocase is antigenically distinct from the other proteins required for initiation and protein synthesis in E. coli.
Vitamin E: absorption, plasma transport and cell uptake (2005)

Substantial progress has been made in characterizing the plasma transport of vitamin E and its delivery to cells. Mechanisms regulating the balance between the cellular uptake and efflux of vitamin E are under investigation. Vitamin E is not only an antioxidant but may also modulate pathways of cell signalling and gene expression. The translation of this new knowledge into clinical studies will help define future indications for vitamin E supplementation.
Japanese guidelines for coxarthrosis (2010)

変形性股関節症について現時点で は世界的にコンセンサスの得られて いる明確な診断基準は存在しない. 大規模疫学調査で有名なものとして はアメリカリウマチ学会(American College of Rheumatology:ACR)基 準がある.これは股関節痛を有し, 1赤血球沈降速度が20mm/h未満,2 大腿骨頭あるいは臼蓋の骨棘形成, 3関節裂隙の狭小化の3項目中2項 目以上が該当するものである.本邦 において股関節症の評価は病期分類 であり前股関節症,初期,進行期, 末期股関節症という曖昧な分類によ り論じられる.特に前股関節症は関 節裂隙狭小化のない臼蓋形成不全や 先天性股関節脱臼後の遺残変形など を含んでおり,明確な分類とは言い 難いが,現在でも慣用的に用いられ ているのが現状である.なお変形性 股関節症のX線診断においては,関 節裂隙の狭小化を計測する方法が検 者間再現性の点において優れてい る(推奨Grade B).さらに単純X 線像における日本人成人股関節の CE角の平均値は男性30~32°,女性 27~34°,Sharp 角の平均値は男性35 ~39°,女性34~42°,acetabular head index(AHI)の平均値は男性82~88 %,女性80~89%と報告されてい る(推奨Grade B). 治 療
Rerouting Flows when Links Fail (2020)

We introduce and investigate reroutable flows, a robust version of network flows in which link failures can be mitigated by rerouting the affected flow. Given a capacitated network, a path flow is reroutable if after failure of an arbitrary arc, we can reroute the interrupted flow from the tail of that arc to the sink, without modifying the flow that is not affected by the failure. Similar types of restoration, which are often termed "local", were previously investigated in the context of network design, such as min-cost capacity planning. In this paper, our interest is in computing maximum flows under this robustness assumption. An important new feature of our model, distinguishing it from existing max robust flow models, is that no flow can get lost in the network. We also study a tightening of reroutable flows, called strictly reroutable flows, making more restrictive assumptions on the capacities available for rerouting. For both variants, we devise a reroutable-flow equivalent of an s-t-cut and show that the corresponding max flow/min cut gap is bounded by 2. It turns out that a strictly reroutable flow of maximum value can be found using a compact LP formulation, whereas the problem of finding a maximum reroutable flow is NP-hard, even when all capacities are in {1, 2}. However, the tightening can be used to get a 2-approximation for reroutable flows. This ratio is tight in general networks, but we show that in the case of unit capacities, every reroutable flow can be transformed into a strictly reroutable flow of same value. While it is NP-hard to compute a maximal integral flow even for unit capacities, we devise a surprisingly simple combinatorial algorithm that finds a half-integral strictly reroutable flow of value 1, or certifies that no such solutions exits. Finally, we also give a hardness result for the case of multiple arc failures.
Anderson localized optical fibers (2013)

<sup>Anderson localization has been a subject of fascination and intense research for more than fifty years. It is highly desirable to harness its curious and interesting properties in practical applications. We have taken a step in this direction by using this phenomenon as the wave guiding mechanism in optical fibers. We have shown, both experimentally and numerically, that for a moderate amount of disorder in optical fibers, transverse localization results in an effective propagating beam diameter that is comparable to that of a typical index-guiding optical fiber.1, 2 In this work, we investigate the effect of macro-bending on the localization properties in a disordered polymer optical fiber both experimentally and numerically. We show that macro-bending in ranges of practical interest does not significantly affect the beam propagation in Anderson localized fibers as long as the strong localization dominates the effect of bending.</sup>
Less invasive surgery for treating adult spinal deformities: ceiling effects for deformity correction with 3 different techniques (2014)

Specific procedures for treating ASD have particular limitations for scoliotic curve correction. Less invasive techniques were associated with a reduced ability to straighten the spine, particularly with advanced curves. These data can guide preoperative technique selection when treating patients with ASD.
&lt;FONT FACE=Symbol&gt;k&lt;/FONT&gt;-Casein, &lt;FONT FACE=Symbol&gt;b&lt;/FONT&gt;-lactoglobulin and growth hormone allele frequencies and genetic distances in Nelore, Gyr, Guzerá, Caracu, Charolais, Canchim and Santa Gertrudis cattle (1999)

The genotypes for k-casein (&lt;FONT FACE="Symbol"&gt;k&lt;/FONT&gt;-CN), &lt;FONT FACE="Symbol"&gt;b&lt;/FONT&gt;-lactoglobulin (&lt;FONT FACE="Symbol"&gt;b&lt;/FONT&gt;-LG) and growth hormone (GH) were determined by polymerase chain reaction (PCR) and restriction enzyme digestion in seven breeds of cattle (Nelore, Gyr, Guzerá, Caracu, Charolais, Canchim and Santa Gertrudis). &lt;FONT FACE="Symbol"&gt;k&lt;/FONT&gt;-Casein had two alleles with the A allele occurring at a higher frequency in Bos indicus breeds (0.93, 0.92 and 0.91% for Gyr, Guzerá and Nelore, respectively). The &lt;FONT FACE="Symbol"&gt;b&lt;/FONT&gt;-lactoglobulin locus had two alleles in all of the breeds. European breeds had a higher frequency of the &lt;FONT FACE="Symbol"&gt;b&lt;/FONT&gt;-LG A allele than Zebu breeds. The GH locus had two alleles (L and V) in Bos taurus and was monomorphic (L allele only) in all of the Bos indicus breeds evaluated. The highest frequency for the V allele was observed in Charolais cattle. The markers used revealed a considerable similarity among breeds, with two main groups being discernible. One group consisted of Zebu and Santa Gertrudis breeds and the other consisted of European and Canchim breeds.
Preoperative statin is associated with decreased operative mortality in high risk coronary artery bypass patients (2010)

Between 2000 and 2004 less than 50% of patients at this institution were receiving statins before admission for isolated CABG. A retrospective analysis of this cohort provides evidence that preoperative statin use is associated with lower operative mortality in high-risk patients.
Pore Pressure Prediction from Seismic Attributes Based on Factor Analysis (2010)

Pore pressure estimation from seismic data is an important issue in exploration studies for prospect detection and drilling planning. The target of this paper is to present a strategy based on statistical techniques to predict pore pressure from seismic attributes. The proposed statistical approach to pore pressure prediction is based on factor analysis method and it is compared to classical deterministic models based on physical equations which link velocities to pressure. We tested the methodology on laboratory measurements and applied it to a real case study in North Africa.
Anthelmintic Activity of liquid Self Emulsifying Drug Delivery System (SEDDS) of Praziquntel (2022)

The present study aims at developing a new adaptable method for evaluation of anthelmintic activity. Liquid self emulsifying drug delivery system was prepared by using design expert method. The anthelmintic activity of emulsion was evaluation by using Indian earthworms at doses 2.5,5,10,15,20 mg/ml. The Praziquantel was used as standard drug (10 mg/ml).The paralysis and death time of earthworms after administering doses were determined. The result of anthelmintic activity of earthworms showed that the earthworms had taken less time for paralysis and less time for death. It can be concluded that earthworms can be used successfully for the anthelmintic activity study as it is easy, prominent, an adaptable to laboratory conditions. Evaluation of anthelmintic activity of any drug when carried out in laboratory conditions by using the isolated worms from nature cannot be adaptable with artificial laboratory conditions. The present anthelmintic activity study reveals a new methodology with earth worms cultured in laboratory conditions. We studied the anthelmintic activities of an Praziquantel drug on earthworms. This result showed that the earthworms had taken less time for paralysis and death. This novel dosage form might be a promising dosage form in the prevention of worm infections for pediatric patients.
Healthcare professional acceptance of telemonitoring for chronic care patients in primary care (2012)

The extended TAM explained a significant portion of the variance in healthcare professionals' intention to use a telemonitoring system for chronic care patients in primary care. The perception of facilitators in the organisational context is the most important variable to consider for increasing healthcare professionals' intention to use the new technology.
1P1-E06 Risk Assessment and Protective Measure of Service Robots (2009)

Recently, robots called "Service robot" are expected to make comfortable life for people. However, service robot is not utilized for people in our society because there are not completely safety rules. The International Organization of Standard require that risk management should be performed by engineer or designer. (ISO14121[1][2], ISO 12100[3]) According to the International Organization of Standard, the safety measure of service robot is depended on engineer or designer. Therefore in this paper we try to suggest the service robot secure, to implement risk assessment. We propose a method for risk evaluation by ISO steps described in this paper. Evaluation experiment are also performed by using soccer robot.
Optically stimulated persistent luminescence of europium-doped LaAlO<sub>3</sub> nanocrystals (2015)

Optically stimulated persistent luminescence was investigated for europium-doped LaAlO3 nanocrystals. This system shows conventional luminescence of both the Eu(3+) line emission and the weak broad-band emission of Eu(2+) upon UV excitation. The persistent luminescence is predominantly associated with the Eu(3+) emission, and can be amplified significantly through irradiation with IR at 975 nm. The conventional luminescence from Eu(3+) is strongly enhanced when the material is excited simultaneously with both UV and IR radiation. The enhancement of persistent luminescence is accompanied by increased persistent photoconductivity. The charge transfer band of the LaAlO3:Eu(3+) nanocrystals in the UV excitation spectra significantly weakens with increasing IR excitation power, also correlating well with the enhancement of persistent luminescence. Finally, a mechanism is presented for the optically stimulated and persistent luminescence in this Eu(2+)- and Eu(3+)-doped LaAlO3 material.
ChemInform Abstract: Challenges for Protein Chemical Synthesis in the 21<sup>th</sup> Century: Bridging Genomics and Proteomics (2001)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Deformation transfer of 3D human shapes and poses on manifolds (2017)

In this paper, we introduce a novel method to transfer the deformation of a human body to another directly on a manifold. There exists a rich literature on transferring deformations based on Euclidean representations. However, a 3D human shape and pose live on a manifold and have a Riemannian structure. The proposed method uses the Lie Bodies manifold representation of 3D triangulated bodies. Its benefits are preserved, namely, minimum required degrees of freedom for any triangle deformation and no heuristics to constrain excessive ones. We give a closed form solution for deformation transfer directly on the Lie Bodies. The deformations have strictly positive determinants ensuring that non-physical deformations are removed. We show examples on three datasets, and highlight differences with the Euclidean deformation transfer.
Role of renal dysfunction in development of cirrhosis complications (2014)

Renal dysfunction is defined as progressing renal failure against chronic and acute failure of a liver at insignificant or total absence of morphological changes in kidneys. Emergence of renal dysfunction at cirrhosis is an integral part of a natural course of the disease characterizing its weight. However the importance of renal dysfunction in development of complications of cirrhosis and its correction today fully are not defined.The aim of research. To estimate the role of renal dysfunction in development of complications of cirrhosis.Materials and methods. 70 patients with cirrhosis took part in the study. 34 patients were hospitalized with ascites resistant to the diuretics and 36 patients had bleeding from esophageal varices. 29 patients have died. Duration of supervision of patients was from 2-3 weeks to 1,5-2 years. All patients had numerous clinical, laboratory and instrumental researches. They included measurement of a daily diuresis, body weight, abdominal circumference. Laboratory researches included, in addition to standard, definition of a creatinine, sodium and potassium level in blood and urine, speeds of a glomerular filtration (GFR). Ultrasonic research (US) of abdominal organs with vessels of an abdominal cavity and renal arteries color duplex scan. Diameter of renal arteries, speed of blood-groove on them and an index of resistance of arteries were estimated. Data of instrumental and laboratory researches were compared with clinical characteristics of a course of a disease and existence of complications. Results. In 14 (39%) patients with bleeding and 28 (82%) with ascites before development of complications the negative water balance – decrease diuresis in comparison with amount of the drunk liquid was noted at the corresponding diuretic therapy that is an early clinical sign of development of renal dysfunction. At laboratory inspection in all patients before hospitalization the tendency to GFR decrease was noted. At an ultrasonic exam of renal arteries resistance index exceeded normal ranges (0,6-0,7) and was 0,95±0,03. In the absence of correction of renal dysfunction the unsatisfactory results of treatment consisting in frequent recurrence of bleeding and high mortality are noted. Conclusions. Clinical manifestation of renal dysfunction is the negative water balance; the laboratory – a tendency to speed of a glomerular filtration decrease; the tool – reduction of diameter of renal arteries, decrease in a volume blood-groove in them, increase in an index of resistance in process of transition from the disease not complicated to the complicated current that took place in 76% of patients. In 82% patients with ascites and 39% with bleeding from esophageal varices clinically significant renal dysfunction took place before development of complications. More than for 60% of patients with early recurrence of bleeding the gepatorenal syndrome was diagnosed. At all died patients hepato-renal insufficiency was noted.
Unraveling the phase-amplitude coupling modulation in a delay-coupled diode lasers functionality (2017)

We numerically investigate the effect of phase-amplitude coupling modulation on power spectra in semiconductor lasers subject to optical injection in a face to face configuration, when a non-negligible injection delay time is taken into account. We find that as phase-amplitude coupling factor &alpha; varies, the system goes through a sequence of phase transactions between In-phase locking states to anti-phase locking states via phase-flip bifurcation. Moreover, we observed the signature of frequency discretization (Frequency Island) and uncovered the physical mechanism for the existence of multi-stability near the phase transitions regimes. Within the windows between successive anti-phases to in-phase locking regions, optical injection induced modulation in alpha, unveiling a remarkable universal feature in the various dynamics of coupled lasers system which could be useful in controlling the chirp or pulse repetition rate of a photonic integrated compact device with the aid of phase control.
Portable Thin Layer Chromatography (TLC) for Field Detection of Explosives (2021)

Abstract not provided
Thymosin Treatment Modulates Production of Interferon (1981)

The maturation of T lymphocytes, the major producers of gamma interferon (IFN- γ), is regulated by thymic hormones. These studies were undertaken to determine whether or not thymic hormones also regulate the production of interferons by C57B1/6 mice. The results clearly indicate an important interrelationship between thymosin and production of interferon. Subcutaneous injection of a single dose of 100 μg or 200 μg of thymosin fraction 5 approximately 40 hr before induction of interferon with Newcastle disease virus (NDV) significantly augmented serum interferon titers compared to the interferon titers induced in untreated mice. Maximum enhancement was observed when a single injection of thymosin fraction 5 was administered between 6 and 12 hr before NDV. Two purified thymosin polypeptides,α1 which induces maturation of helper T cells and α7 which induces maturation of suppressor T cells, had opposite effects. Three injections of 5 μg of thymosin α1 administered before NDV increased production of interferon while 3 daily injections of 1 μg of thymosin α7, suppressed the responsiveness of mice to NDV. This observation represents the first report of a direct effect of purified thymic hormones on the production of interferon. Thymosin fraction 5 also enhanced production of IFN- γ. Enhanced interferon production was observed in Concanavalin A (Con A)-stimulated cultures of spleen cells from mice treated in vivo with 150 pg of thymosin fraction 5. The circadian rhythm of thymosin α1 levels and the titer of interferon induced conincided. Significantly higher titers of interferon were induced when NDV was injected at midnight than were induced when NDV was injected in the morning. The results of this study suggest a significant role for the endocrine thymus in modulating interferon production and provide a rationale for exploring the role of thymosin in the treatment of viral diseases and perhaps other infectious diseases.
A validated combined musculotendon path and muscle-joint kinematics model for the human hand (2019)

Neuromusculoskeletal models provide a mathematical tool for understanding and simulating human motor control and neuromechanics. In this work, we propose a combined computational model for the musculotendon paths and muscle-joint kinematics for the human hand, including all extrinsic and intrinsic muscles. This model is implemented based on the anatomical descriptions and a human hand dissection study. The model takes joint angles as input and estimates the musculotendon lengths, length change rates, and excursion moment arms. The proposed model is simulated to generate according moment arms, which are compared with cadaver measurements available from literature in terms of similarity coefficient s. For most muscles compared, high similarity with <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:mrow><mml:mi>s</mml:mi><mml:mo>≥</mml:mo><mml:mn>0.70</mml:mn></mml:mrow></mml:math> for 92% of cases is achieved between the modeled and the measured moment arms. These results suggest the correctness of modeled moment arms and imply the feasibility of modeled musculotendon paths, lengths, and length change rates.
A Novel Technique for Visualizing Electron Beam Induced Charging (2003)

Journal Article A Novel Technique for Visualizing Electron Beam Induced Charging Get access Xiaohu Tang, Xiaohu Tang Electron Microscope Facility, University of Tennessee, Knoxville, TN 37996-0840 USA Search for other works by this author on: Oxford Academic Google Scholar David C Joy David C Joy Electron Microscope Facility, University of Tennessee, Knoxville, TN 37996-0840 USAOak Ridge National Laboratory, Oak Ridge, TN 37831-6064 USA Search for other works by this author on: Oxford Academic Google Scholar Microscopy and Microanalysis, Volume 9, Issue S02, 1 August 2003, Pages 980–981, https://doi.org/10.1017/S1431927603444905 Published: 24 July 2003
Ultrasound measurement of the vertebral level of Tuffier's line in elderly women (2016)

The vertebral level of Tuffier's line determined with ultrasound measurement in the left lateral decubitus flexed position was more cephalad in the elderly women than in those of the control group. Therefore, we should consider that the needle could be inserted at a higher level than expected, and use care in determining the level of needle insertion during spinal anesthesia in elderly women.
ChemInform Abstract: Cerebral Antihypoxic Activity of New Thienyldihydropyridines. (1995)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Improved Model Checking Techniques for State Space Analysis of Gene Regulatory Networks (2010)

A better understanding of the behavior of a cell, as a system, depends on our ability to model and understand the complex regulatory mechanisms that control gene expression. High level, qualitative models of gene regulatory networks can be used to analyze and characterize the behavior of complex systems, and to provide important insights on the behavior of these systems. In this chapter, we describe a number of additional functionalities that, when supported by a symbolic model checker, make it possible to answer important questions about the nature of the state spaces of gene regulatory networks, such as the nature and size of attractors, and the characteristics of the basins of attraction. We illustrate the type of analysis that can be performed by applying an improved model checker to two well studied gene regulatory models, the network that controls the cell cycle in the yeast S. cerevisiae, and the network that regulates formation of the dorsal-ventral boundary in D. melanogaster. The results show that the insights provided by the analysis can be used to understand and improve the models, and to formulate hypotheses that are biologically relevant and that can be confirmed experimentally.