gebhart/patrepeval huggingface dataset:
Robot-Assisted Sacrocolpopexy versus Trans-Vaginal Multicompartment Prolapse Repair: Impact on Lower Bowel Tract Function (2023)

RSC and TVMLP successfully corrected multicompartment POP. RSC showed a greater improvement in the total Agachan-Wexner score and lower bowel symptoms.
Graphical-based multivariate analysis for knee joint clinical and kinematic data correlation assessment (2020)

A large amount of data including joint kinematics, joint kinetics, clinical and functional measurements constitutes the clinical gait analysis basis which is a process whereby quantitative gait information are collected to aid in clinical decision-making. Therefore, better understanding the relationship between the biomechanical and clinical data for the knee osteoarthritis (OA) patient is for a relevant importance. It's the purpose of this paper, which aims to analyze and visualize the correlation structure between biomechanical characteristics and clinical symptoms, and thus to provide an additional knowledge from the coupling of these parameters that will be useful for the pathology assessment of knee-joint disease in the end-staged knee OA patients. We perform two multivariate statistical approaches, first, a Canonical Correlation Analysis (CCA) to assess the multivariate association and, second, a graphical- based representation of the multivariate correlation to better understand the association between these multivariate data. Results show the usefulness of using such multivariate approaches to highlight association and specific correlation structure between the features and to extract meaningful information.
Concerted Photoluminescence of Electrochemically Self-Assembled CuSCN/Stilbazolium Dye Hybrid Thin Films (2019)

Hybrid thin films of crystalline CuSCN and 4-(<i>N</i>,<i>N</i>-dimethylamino)-4'-(<i>N</i>'-methyl)stilbazolium (DAS) in three distinctively different nanostructures were obtained by electrochemical self-assembly from a single pot containing all the chemical ingredients. Their optical properties for UV-vis-NIR absorption, photoluminescence (PL), and PL excitation spectra were examined between 77 and 298 K, in comparison with solution and solid powder of DAS tosylate (DAST). Unlike all other dyes we tested before, PL of DAS was not quenched but rather enhanced when hybridized with CuSCN. DAST exhibited a strong exciton-phonon coupling to weaken, broaden, and red shift PL at room temperature, so that it inversely is strongly enhanced, sharpened, and blue-shifted at 77 K. The PL of the same dye in the hybrid thin film, however, shows a slight red shift and only a moderate enhancement at reduced temperatures due to strong exciton stabilization in dielectric environment of CuSCN and concerted PL by energy transfer from CuSCN to DAS luminophore, making it a unique nearly temperature-independent luminescent material.
Smart home for security and low power consumption with common network modules based on RT middleware (2010)

The robot technology parts (RT parts) can be arranged on environment. The RT parts are controlled through the network. The concept of Ubiquitous Robotics is to support human life by RT parts on the environment. Smart home for secure and ecology has been built by corporative control of RT parts and common network on the national project "Open Innovation Promotion by Utilizing Basic Robotic Technology" in New Energy and Industrial Technology Development Organization (NEDO). In this paper, the concept of the smart home with distributed RT parts will be introduced. The smart home has two main functions. One is intelligent window. Another one is intelligent air condition system. The intelligent window works to guard a home and support human. The intelligent air condition system works temperature and humidity control in the home with low power consumption. In above functions, the common home network is important. In order to connect Any RT parts, the common network device was developed with RT middle ware architecture.
Real-Time Simulation of Deep Azimuthal Resistivity Tool in 2D Fault Model Using Neural Networks (2018)

Abstract In most cases, interpretation of resistivity measurements is performed using 1D multilayered formation models that are used to fit data locally in real-time applications. While drilling high-angle or horizontal wells, more complex scenarios may occur, such as faults, pinch-outs, or unconformities. In these cases, resistivity logging data inversion should be performed using at least a 2D model, which is a more complex computational problem. This paper presents a neural networks approach for solving this problem exemplified by the application of a deep azimuthal resistivity tool for geosteering in the vicinity of a tectonic fault. The tool operational frequencies of 400 kHz and 2 MHz produce eight measurements with a coaxial arrangement of transmitters and receivers, and two azimuthally sensitive measurements with axial transmitters and transverse receivers. This paper considers a 2D model of a tectonic fault composed of three parallel layers on the one side of a displacement plane and the same three layers on the other side dislocated at a certain distance along the displacement plane. The model is described with nine independent parameters. The artificial neural networks (ANNs) were designed and trained to calculate the tool signals based on the model parameters. The training was carried out using a synthetic database of 4·105 elements containing the model parameters and corresponding tool signals. The database was calculated using distributed computations with in-house Pie2D software that used the boundary integral equation technique. To estimate the accuracy of the ANNs designed, the signals calculated with the networks were compared against the exact values obtained with Pie2D for an independent sample of 1.8·104 points. The comparison gave a good match for all 10 measurements, with the relative error comprising less than one standard tool measurement error for most points of the sample. Computation with the ANN required a few microseconds to calculate one signal, while the algorithm based on boundary integral equations required several minutes. The obtained acceleration of ~106 indicates many opportunities for modeling and inversion of logging-while-drilling data.
Compressed Principal Component Regression (C–PCR) Algorithm and FPGA Validation (2020)

To address the hardware and/or software implementation issues of principal component regression (PCR), we propose a novel algorithm called compressed PCR (C-PCR). C-PCR projects the input data to a lower dimensional space first, and then applies the compressed data to a significantly smaller PCR engine. We show that C-PCR can lower the computational complexity of PCR with a factor of compression ratio (CR) squared, i.e., CR <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> . Moreover, the output signal of C-PCR follows that of PCR with a small error, which increases with CR, when the projections are random. Using datasets of prerecorded brain neurochemicals, we experimentally show that C-PCR can achieve CRs as high as ~ 10. As far as hardware implementation is concerned, the experimental results show that reduction rates of 32% to 45% in different FPGA resources can be achieved using C-PCR.
Isolated resonant full-bridge converter with magnetic integration (2017)

Nowadays technological developments in modern microprocessors have brought better computing performance and have triggered the demand for high-efficiency power supply. The common trend in networking applications is to have a 48V dc distribution bus to increase system efficiency, while the supply of the microprocessor is usually obtained by a two-stage conversion process having an intermediate 12V dc bus. This paper presents a single-stage approach for the isolated voltage regulation module (VRM) based on a resonant topology that inherently integrates the multi-phase approach. In order to fit the layout constraints of the processor mother board, this paper also presents some magnetic architectures which integrate the magnetic parts. Compared to a classical discrete implementation, the proposed integrated magnetic structures have smaller total volume. In this paper we will compare the magnetic structures in the same application that is a processor power supply conversion from 48V bus. The proposed integrated magnetic architectures can be applied to other topologies as conventional ZVS full bridge. Experimental results on a 250A, 1.8 V multiphase isolated conversion are provided to show the effectiveness of the proposed solutions.
Primary lens instability in ten related cats: clinical and genetic considerations (2011)

These observations suggest an inherent zonular defect unrelated to extraneous factors. The family relationship is compatible with a possible genetic basis, and the pedigree suggests that the condition could be dominant. Data also suggest the mutation in the FBN1 gene could be responsible for primary lens luxation in this pedigree of cats.
<i>GNAO1</i> encephalopathy (2017)

Our findings support the causative role of <i>GNAO1</i> mutations in an expanded spectrum of early-onset epilepsy and movement disorders, frequently exacerbated by specific triggers and at times associated with self-injurious behavior. Tetrabenazine and DBS were the most useful treatments for dyskinesia.
A Full-Scale Study on the Partitioning of Trace Elements in Municipal Solid Waste Incineration – Effects of Firing Different Waste Types (2008)

Waste incineration on a grate is a well-established thermal treatment technology in Denmark and several other countries. The method is flexible with respect to operation, it allows for recovery of energy, it reduces the volume of solid waste significantly (by a factor of 8−10), and advanced flue gas cleaning technologies ensures very low emissions from modern incineration plants. In 2005, 24% of the total reported Danish waste production was incinerated. However, the presence of inorganic constituents such as alkali metals, Cl, S, and heavy metals in the waste constitute an essential challenge in waste incineration, both with respect to operational issues and due to environmental concerns. Formation of acidic pollutants, high mass loading of aerosols, and deposition of potentially corrosive components on heat transfer surfaces are among the encountered problems caused by volatile alkali compounds and heavy metals during combustion, and the potential leaching of heavy metals from the solid residues upon di...
Ultra high-field (7 T) multi-resolution fMRI data for orientation decoding in visual cortex (2017)

Multivariate pattern classification methods have been successfully applied to decode orientation of visual grating stimuli from BOLD fMRI activity recorded in human visual cortex (Kamitani and Tong, 2005; Haynes and Rees, 2005) [12], [10]. Though there has been extensive research investigating the true spatial scale of the orientation specific signals (Op de Beeck, 2010; Swisher et al., 2010; Alink et al., 2013; Freeman et al., 2011, 2013) [2], [15], [1], [4], [5], it remained inconclusive what spatial acquisition resolution is required, or is optimal, for decoding analyses. The research article entitled "The effect of acquisition resolution on orientation decoding from V1 BOLD fMRI at 7 T" Sengupta et al. (2017) [14] studied the effect of spatial acquisition resolution and also analyzed the strength and spatial scale of orientation discriminating signals. In this article, for the first time, we present empirical ultra high-field fMRI data, obtained as a part of the aforementioned study, which were recorded at four spatial resolutions (0.8 mm, 1.4 mm, 2 mm, and 3 mm isotropic voxel size) for orientation decoding in visual cortex. The dataset is compliant with the <i>BIDS</i> (Brain Imaging Data Structure) format, and freely available from the <i>OpenfMRI</i> portal (dataset accession number: http://openfmri.org/dataset/ds000113c ds000113c).
Experiences with mouse control in multi-display environments (2010)

It is now increasingly common to extend private workstations with large public displays into a shared multi-display environment (MDE). Mouse-based interaction across multiple displays provides a convenient way to quickly shift between private work on the personal monitor and tightly coupled collaboration on shared display spaces (Figure 1). However, mouse pointer navigation can be negatively influenced by display factors in the environment and thereby limit fluid interaction across displays. We report findings from an experiment comparing four mouse pointer navigation techniques in a heterogeneous MDE.
Biomaterials Research in India—An <i>ACS Applied Bio Materials</i> Forum (2019)

ADVERTISEMENT RETURN TO ISSUEEditorialNEXTBiomaterials Research in India—An ACS Applied Bio Materials ForumParameswar K. IyerParameswar K. IyerIndian Institute of Technology GuwahatiMore by Parameswar K. Iyerhttp://orcid.org/0000-0003-4126-3774 and Kaushik ChatterjeeKaushik ChatterjeeIndian Institute of ScienceMore by Kaushik Chatterjeehttp://orcid.org/0000-0002-7204-2926Cite this: ACS Appl. Bio Mater. 2019, 2, 12, 5216–5217Publication Date (Web):December 16, 2019Publication History Published online16 December 2019Published inissue 16 December 2019https://pubs.acs.org/doi/10.1021/acsabm.9b01058https://doi.org/10.1021/acsabm.9b01058editorialACS PublicationsCopyright © 2019 American Chemical Society. This publication is available under these Terms of Use. Request reuse permissions This publication is free to access through this site. Learn MoreArticle Views2176Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail PDF (272 KB) Get e-AlertscloseSUBJECTS:Biocompatibility,Biomaterials,Cells,Drug delivery,Nanoparticles Get e-Alerts
Human γδ T-Cells: From Surface Receptors to the Therapy of High-Risk Leukemias (2018)

γδ T lymphocytes are potent effector cells, capable of efficiently killing tumor and leukemia cells. Their activation is mediated by γδ T-cell receptor (TCR) and by activating receptors shared with NK cells (e.g., NKG2D and DNAM-1). γδ T-cell triggering occurs upon interaction with specific ligands, including phosphoantigens (for Vγ9Vδ2 TCR), MICA-B and UL16 binding protein (for NKG2D), and PVR and Nectin-2 (for DNAM-1). They also respond to cytokines undergoing proliferation and release of cytokines/chemokines. Although at the genomic level γδ T-cells have the potential of an extraordinary TCR diversification, in tissues they display a restricted repertoire. Recent studies have identified various γδ TCR rearrangements following either hematopoietic stem cell transplantation (HSCT) or cytomegalovirus infection, accounting for their "adaptive" potential. In humans, peripheral blood γδ T-cells are primarily composed of Vγ9Vδ2 chains, while a minor proportion express Vδ1. They do not recognize antigens in the context of MHC molecules, thus bypassing tumor escape based on MHC class I downregulation. In view of their potent antileukemia activity and absence of any relevant graft-versus-host disease-inducing effect, γδ T-cells may play an important role in the successful clinical outcome of patients undergoing HLA-haploidentical HSCT depleted of TCR αβ T/CD19<sup>+</sup> B lymphocytes to cure high-risk acute leukemias. In this setting, high numbers of both γδ T-cells (Vδ1 and Vδ2) and NK cells are infused together with CD34<sup>+</sup> HSC and may contribute to rapid control of infections and leukemia relapse. Notably, zoledronic acid potentiates the cytolytic activity of γδ T-cells <i>in vitro</i> and its infusion in patients strongly promotes γδ T-cell differentiation and cytolytic activity; thus, treatment with this agent may contribute to further improve the patient clinical outcome after HLA-haploidentical HSCT depleted of TCR αβ T/CD19<sup>+</sup> B lymphocytes.
Supplemental Figures 7-8 from Tumor-Derived CCL2 Mediates Resistance to Radiotherapy in Pancreatic Ductal Adenocarcinoma (2023)

&lt;p&gt;Supplemental Figure 7: Neutralization of CCL2 delays tumor growth in vivo; Supplemental Figure 8: CCR2 is expressed by a subset of CD45+ leukocytes in tumors&lt;/p&gt;
A multi-genotype therapeutic human papillomavirus vaccine elicits potent T cell responses to conserved regions of early proteins (2019)

Despite an efficacious prophylactic human papillomavirus (HPV) vaccine there is still a considerable global burden of HPV-related disease. Therapeutic vaccines that could prevent cancers in at-risk women are urgently needed. Most candidate therapeutic vaccines have focused on two high-risk (hr) HPV genotypes, 16 and 18, and two viral targets, E6 and E7, which may limit global coverage and efficacy. We designed the synthetic gene '5GHPV3' by selecting conserved regions from each of the six early proteins and generating consensus sequences to represent five hrHPV genotypes. 5GHPV3 was delivered by plasmid DNA, chimpanzee adenovirus (ChAdOx1) and modified vaccinia Ankara (MVA) vectors in prime-boost regimens to mice. ChAdOx1-5GHPV3 / MVA-5GHPV3 induced higher magnitude and more durable HPV-specific T cell responses than other regimens. Vaccine-induced T cells were polyfunctional and persisted at high frequencies for at least six weeks. Importantly, HPV-specific effector CD8 + T cells were detected in the cervix following systemic administration of ChAdOx1-5GHPV3 / MVA-5GHPV3 and increased in frequency over time, indicating continued trafficking of T cells to the cervix. Finally, T cells specific for 5GHPV3 encoded antigens were detected by IFN-γ Elispot in women with current or past hrHPV infections, confirming the presence of epitopes relevant to natural immune control.
Sex-determined susceptibility and differential IFN-gamma and TNF-alpha mRNA expression in DBA/2 mice infected with Leishmania mexicana. (1995)

Female DBA/2 mice have been shown to be relatively resistant to infection with Leishmania mexicana when compared with male mice. In order to determine the immunological basis behind this difference the draining lymph nodes from male and female DBA/2 mice were excised and the RNA extracted at different time-points following infection. Following reverse transcription, the polymerase chain reaction (PCR) was used to identify mRNA transcripts for interferon-gamma (IFN-gamma), tumour necrosis factor-alpha (TNF-alpha), interleukin-4 (IL-4), IL-10 and IL-12. The evolution of cytokine mRNA production was slow in both male and female mice as no newly synthesized transcripts were identified 5 weeks after infection. IL-10 was expressed constitutively in non-infected mice and was present throughout the experiment in all animals. By week 8, a clear dichotomy in cytokine mRNA expression was emerging between the resistant female and susceptible male mice. Whereas all females expressed IFN-gamma and one also expressed TNF-alpha only two out of five males expressed IFN-gamma and four out of five expressed TNF-alpha. The greatest lesion sizes at this time were recorded from those mice expressing TNF-alpha but not IFN-gamma. No differences in IL-4 or IL-12 were noted with transcripts for both cytokines present in both sexes at week 8. By week 12 males had developed large non-healing nodules and in females lesions had either disappeared or were slow growing. At this time only transcripts for TNF-alpha were present in males and only those for IFN-gamma were detected in females. Treatment of female mice following infection with IFN-gamma neutralizing antibody resulted in lesion growth equivalent to male mice. IFN-gamma production would, therefore, appear sufficient to limit the growth of L. mexicana in female DBA/2 mice while TNF-alpha production in the absence of IFN-gamma confers no protection to DBA/2 male mice.
Predictive Value of an Age-Based Modification of the National Early Warning System in Hospitalized Patients With COVID-19 (2021)

NEWS and NEWS+age showed similar test characteristics in an MHS COVID-19 cohort. Notably, low baseline scores had an excellent negative predictive value. Given their easy applicability, these scoring systems may be useful in resource-limited settings to identify COVID-19 patients who are unlikely to progress to critical illness.
Femtosecond X-ray solution scattering reveals that bond formation mechanism of a gold trimer complex is independent of excitation wavelength (2016)

The [Au(CN)2 (-)]3 trimer in water experiences a strong van der Waals interaction between the d(10) gold atoms due to large relativistic effect and can serve as an excellent model system to study the bond formation process in real time. The trimer in the ground state (S0) exists as a bent structure without the covalent bond between the gold atoms, and upon the laser excitation, one electron in the antibonding orbital goes to the bonding orbital, thereby inducing the formation of a covalent bond between gold atoms. This process has been studied by various time-resolved techniques, and most of the interpretation on the structure and dynamics converge except that the structure of the first intermediate (S1) has been debated due to different interpretations between femtosecond optical spectroscopy and femtosecond X-ray solution scattering. Recently, the excitation wavelength of 267 nm employed in our previous scattering experiment was suggested as the culprit for misinterpretation. Here, we revisited this issue by performing femtosecond X-ray solution scattering with 310 nm excitation and compared the results with our previous study employing 267 nm excitation. The data show that a linear S1 structure is formed within 500 fs regardless of excitation wavelength and the structural dynamics observed at both excitation wavelengths are identical to each other within experimental errors.
Cytosine methylation of mature microRNAs inhibits their functions and is associated with poor prognosis in glioblastoma multiforme (2020)

Together, our results indicate that the DNMT3A/AGO4-mediated cytosine methylation of miRNA negatively.
Monte Carlo Simulation of Exciton Bimolecular Annihilation Dynamics in Supramolecular Semiconductor Architectures (2007)

We present a simulation of exciton dynamics in supramolecular assemblies of an oligo-p-phenylenevinylene derivative monofunctionalised with a quadruple hydrogen-bonding group (MOPV). MOPV molecules form helical stacks in dodecane solution through solvophobic and π−π interactions with thermotropic reversibility. We apply a model of incoherent excitation hopping using a Monte Carlo scheme to extract microscopic physical quantities relevant to energy diffusion and bimolecular annihilation processes within isolated nanostructures. We compare the simulation to ultrafast spectroscopic data, namely photoinduced absorption transients at various excitation fluences, their polarization anisotropy, and the dynamic photoluminescence red-shift. We observe that energy diffusion and bimolecular annihilation processes can be described with the same microscopic model based on a Förster-like model that takes into account the spatial extent of the excited state; these two processes are interconnected via the same underlying physics. We extract a high diffusion coefficient (∼0.08 cm2 s-1) over the first few picoseconds following excitation, which plays an important role in dictating the bimolecular annihilation dynamics.