gebhart/patrepeval huggingface dataset:
Development in helicopter tail boom strake applications in the US (1988)

Two new coruleoellagic acid derivatives, 3,4',5,5',-tetramethylcoruleoellagic acid <b>(1)</b>; 3',4,4',5,5'-pentamethylcoruleoellagic acid <b>(2)</b> and a new friedelane-type triterpene derivative rinol <b>(5)</b>, were isolated from leaves and trunk bark of <i>Rinorea oblongifolia</i> (Violaceae) along with seven known compounds including 3,3',4,4',5'-pentamethylcoruleoellagic acid <b>(3)</b>, hexamethylcoruleoellagic acid <b>(4),</b> 28-hydroxyfriedelin <b>(6),</b> friedelin <b>(7),</b> friedelan-3-ol <b>(8),</b> scopoletin <b>(9)</b> and β-sitosterol-3-<i>O</i>-β-D-glucopyranoside <b>(10).</b> Their structures were elucidated by means of spectroscopic methods including IR, 1D and 2D NMR in conjunction with mass spectrometry. Crude extracts of leaves and trunk bark as well as compounds <b>1-4</b> were evaluated for their antibacterial activities against 7 pathogenic bacterial strains (<i>Streptococcus pneumoniae</i> ATCC49619, <i>Staphylococcus aureus</i> ATCC 43300, <i>Klepsiella pneumoniae</i> ATCC 700603, <i>Haemophilus influenza</i> ATCC 49247, <i>Escherichia coli</i> ATCC 25922, <i>Pseudomonas aeruginosa</i> HM601, <i>Staphylococcus aureus</i> BAA 977). Compound <b>(3)</b> displayed noteworthy activity against <i>Haemophilus influenza</i> with MIC value of 9.38 µg/mL.
ChemInform Abstract: Titanium Fluoride Complexes as Catalysts for the Enantioselective Addition of Me<sub>3</sub>Al to Aldehydes. (1999)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Influence of Bone Structure on Mechanical Properties of Bovine and Swine Compact Bones (2005)

This DOI is not currently attached to any metadata records. DOIs can’t actually ever be deleted (they’re persistent), but sometimes our members create DOIs in error. We do have a process to approximate deletion which we follow only in rare cases where the DOI has been genuinely created in error, and most crucially, if the DOI has never been published anywhere online or in print and never otherwise distributed to or communicated with anyone (authors, readers, reviewers, etc.
Electrochemical modulation of luminescence from an interfacial probe during redox switching of polypyrrole (1988)

Steady-state measurements were used to demonstrate how luminescence from an interfacial probe such as pyrene or [Ru(bpy)3Cl2](bpy = 2,2′-bipyridine) may be modulated by redox switching of a polypyrrole electrode between the insulating and electronically conductive states.
Mid‐Term Outcomes of Endoscopic Gluteus Medius Repair With Concomitant Arthroscopic Labral Treatment: A Propensity‐Matched Controlled Study (2020)

III, retrospective comparative study.
Leishmania infantum β-Tubulin Identified by Reverse Engineering Technology through Phage Display Applied as Theranostic Marker for Human Visceral Leishmaniasis (2019)

Two Leishmania infantum mimotopes (B10 and C01) identified by phage display showed to be antigenic and immunogenic for visceral (VL) and tegumentary (TL) leishmaniasis; however, their biological targets in the parasites have not been identified. The aim of the present study was to investigate the native antigens expressing both mimotopes, and to use them in distinct immunological assays. For this, a subtractive phage display technology was used, where a combinatorial library of single-chain variable fragments (scFv) was employed and the most reactive monoclonal antibodies for each target were captured, being the target antigens identified by mass spectrometry. Results in immunoblotting and immunoprecipitation assays showed that both monoclonal scFvs antibodies identified the β-tubulin protein as the target antigen in L. infantum. To validate these findings, the recombinant protein was cloned, purified and tested for the serodiagnosis of human leishmaniasis, and its immunogenicity was evaluated in PBMC derived from healthy subjects and treated or untreated VL patients. Results showed high diagnostic efficacy, as well as the development of a specific Th1 immune response in the cell cultures, since higher IFN-γ and lower IL-10 production was found.
Genome-wide association of functional traits linked with <i>Campylobacter jejuni</i> survival from farm to fork (2016)

Campylobacter jejuni is a major cause of bacterial gastroenteritis worldwide, primarily associated with the consumption of contaminated poultry. C. jejuni lineages vary in host range and prevalence in human infection, suggesting differences in survival throughout the poultry processing chain. From 7,343 MLST-characterised isolates, we sequenced 600 C. jejuni and C. coli isolates from various stages of poultry processing and clinical cases. A genome-wide association study (GWAS) in C. jejuni ST-21 and ST-45 complexes identified genetic elements over-represented in clinical isolates that increased in frequency throughout the poultry processing chain. Disease-associated SNPs were distinct in these complexes, sometimes organised in haplotype blocks. The function of genes containing associated elements was investigated, demonstrating roles for cj1377c in formate metabolism, nuoK in aerobic survival and oxidative respiration, and cj1368-70 in nucleotide salvage. This work demonstrates the utility of GWAS for investigating transmission in natural zoonotic pathogen populations and provides evidence that major C. jejuni lineages have distinct genotypes associated with survival, within the host specific niche, from farm to fork.
Normal dendritic cell mobilization to lymph nodes under conditions of severe lymphatic hypoplasia (2012)

To address the requirement for lymphatic capillaries in dendritic cell (DC) mobilization from skin to lymph nodes (LNs), we used mice bearing one inactivated allele of vascular endothelial growth factor receptor 3 (VEGFR3) where skin lymphatic capillaries are reported absent. Unexpectedly, DC mobilization from the back skin to draining LNs was similar in magnitude, and kinetics to control mice and humoral immunity appeared intact. By contrast, DC migration from body extremities, including ear and forepaws, was ablated. An evaluation in different regions of skin revealed rare patches of lymphatic capillaries only in body trunk areas where migration was intact. That is, whereas the ear skin was totally devoid of lymphatic capillaries, residual capillaries in the back skin were present though retained only at ∼10% normal density. This reduction in density markedly reduced the clearance of soluble tracers, indicating that normal cell migration was spared under conditions when lymphatic transport function was poor. Residual lymphatic capillaries expressed slightly higher levels of CCL21 and migration of skin DCs to LNs remained dependent on CCR7 in Chy mice. DC migration from the ear could be rescued by the introduction of a limited number of lymphatic capillaries through skin transplantation. Thus, the development of lymphatic capillaries in the skin of body extremities was more severely impacted by a mutant copy of VEGFR3 than trunk skin, but lymphatic transport function was markedly reduced throughout the skin, demonstrating that even under conditions when a marked loss in lymphatic capillary density reduces lymph transport, DC migration from skin to LNs remains normal.
Spatial Radiation Dose Influence on Xerostomia Recovery and Its Comparison to Acute Incidence in Patients With Head and Neck Cancer (2019)

The superior portion of the 2 PGs (low dose region) are the most influential on xerostomia recovery and seem to be equal in their contribution. The dissimilarity of the influence pattern between injury and recovery suggests different underlying mechanisms. The importance pattern identified by spatial radiation dose and machine learning methods can improve our understanding of normal tissue toxicities in RT. Further external validation is warranted.
Mathematical optimization of contrast concentration for t<sub>1</sub>‐weighted spoiled gradient echo imaging (2015)

This work provides validated mathematical expressions for contrast enhanced T1-weighted SGRE imaging and may provide guidance for contrast dosing and injection protocols, as well as for novel pulse sequence design.
Enhanced Cycleabity in Lithium Ion Batteries: Resulting from Atomic Layer Depostion of Al<sub>2</sub>O<sub>3</sub> or TiO<sub>2</sub> on LiCoO<sub>2</sub> Electrodes (2012)

This study reports the preparation of Al2O3 and TiO2 coatings on the as-prepared LiCoO2 electrodes using atomic layer deposition (ALD). A thin Al2O3 ALD coating was shown to eliminate capacity fading effectively during repeated charging and discharging, whereas a TiO2 coating led to significant improvement only at high cycle numbers. An analysis of the differential capacity versus potential curves suggests that this poorer cycling performance could be related to the participation of the TiO2 thin film in the redox reaction. Graphical representation of the energy levels of the various ALD coatings on LiCoO2 during charging and discharging indicated that the redox current is impeded at the Al2O3–LiCoO2 junction, whereas electrons and holes were energetic enough to flow into the TiO2 because of the smaller band gap energy. The barrier between the valence band maxima of TiO2 and LiCoO2 expands as the charge–discharge cycle number increases, eventually making TiO2 redox-inactive. These conclusions are supported by both XPS spectra and the cycle performance in the established literature references. Our results suggest that large band gap materials should be considered to be potentially useful ALD coatings on cathode materials.
Heterolytic Cleavage of the C−C Bond of Acetonitrile with Simple Monomeric CuII Complexes: Melding Old Copper Chemistry with New Reactivity (2001)

Acetonitrile might not be an “innocent” solvent after all: The monomeric CuII complex [Cu(dmppy)(en)] (see structure) readily cleaves the C−C bond of acetonitrile under ambient conditions. Previously, heterolytic cleavage of the C−C bond of acetonitrile had only been achieved by phosphane complexes of metals in low oxidation states. dmppyH2=N,N′-dimethylpyridine-2,6-dicarboxamide, en=ethylenediamine.
Reservoir heterogeneity in the Vanguard Field, UKCS (1993)

Abstract The Rotliegendes Group in the Vanguard Field, UKCS, consists of a series of aeolian, fluvial, and reworked aeolian sediments, organized into four broadly correlatable lithostratigraphical units. Within these units, reservoir properties are strongly linked to lithofacies, with aeolian dune sandstones possessing the best porosity and permeability. A comparison of production log spinner profiles (PLT) with detailed sedimenttological logs from three development wells shows that gas production is intimately associated with specific lithofacies and their spatial organization. Although dune sandstones in the upper section of the Rotliegendes have good petrophysical characteristics, they do not contribute significantly to production because they are contained within laterally extensive and relatively impermeable interdune sandstones. Most production comes from 15–30 feet thick and highly permeable (100–1000 mD) dune foreset intervals deposited near the bases of large aeolian dunes. Significant interwell variation in production rates and in porosity exists for all lithofacies due to the variable extent of diagensis. Petrographical studies, combined with whole-rock geochemical analysis, have outlined a diagenetic sequence for the field. Two end-member mineralogical assemblages are identified which are closely linked to reservoir quality. High porosity wells contain a chlorite-K-feldspar-quartz-dolomite assemblage while low porosity wells contain an illite-quartz-ankerite assemblage. Empirical evidence shows that porosity loss is associated with conversion of K-feldspar, chlorite and dolomite to illite and ankerite, and is due to compaction rather than cementation. Post-depositional faults acted as conduits for fluid which altered mineralogy, removed soluble components and, in one case, introduced anhydrite cement.
Hydrazido(1-) and 2,2-dimethylhydrazido(1-) derivatives of permethylscandocene. Preparation and structural characterization of their products from reactions with acetonitrile: (.eta.5-C5Me5)2ScN(H)C(CH3)NNH2 and (.eta.5-C5Me5)2ScN(H)C(CH3)NNMe2 (1990)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTHydrazido(1-) and 2,2-dimethylhydrazido(1-) derivatives of permethylscandocene. Preparation and structural characterization of their products from reactions with acetonitrile: (.eta.5-C5Me5)2ScN(H)C(CH3)NNH2 and (.eta.5-C5Me5)2ScN(H)C(CH3)NNMe2Pamela J. Shapiro, Lawrence M. Henling, Richard E. Marsh, and John E. BercawCite this: Inorg. Chem. 1990, 29, 22, 4560–4565Publication Date (Print):October 1, 1990Publication History Published online1 May 2002Published inissue 1 October 1990https://pubs.acs.org/doi/10.1021/ic00347a045https://doi.org/10.1021/ic00347a045research-articleACS PublicationsRequest reuse permissionsArticle Views168Altmetric-Citations30LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
Robust Self-Supervised Learning of Deterministic Errors in Single-Plane (Monoplanar) and Dual-Plane (Biplanar) X-Ray Fluoroscopy (2020)

Fluoroscopic imaging that captures X-ray images at video framerates is advantageous for guiding catheter insertions by vascular surgeons and interventional radiologists. Visualizing the dynamical movements non-invasively allows complex surgical procedures to be performed with less trauma to the patient. To improve surgical precision, endovascular procedures can benefit from more accurate fluoroscopy data via calibration. This paper presents a robust self-calibration algorithm suitable for single-plane and dual-plane fluoroscopy. A three-dimensional (3D) target field was imaged by the fluoroscope in a strong geometric network configuration. The unknown 3D positions of targets and the fluoroscope pose were estimated simultaneously by maximizing the likelihood of the Student-t probability distribution function. A smoothed k-nearest-neighbour (kNN) regression is then used to model the deterministic component of the image reprojection error of the robust bundle adjustment. The Maximum Likelihood Estimation step and the kNN regression step are then repeated iteratively until convergence. Four different error modeling schemes were compared while varying the quantity of training images. It was found that using a smoothed kNN regression can automatically model the systematic errors in fluoroscopy with similar accuracy as a human expert using a small training dataset. When all training images were used, the 3D mapping error was reduced from 0.61-0.83 mm to 0.04 mm post-calibration (94.2-95.7% improvement), and the 2D reprojection error was reduced from 1.17-1.31 to 0.20-0.21 pixels (83.2-83.8% improvement). When using biplanar fluoroscopy, the 3D measurement accuracy of the system improved from 0.60 mm to 0.32 mm (47.2% improvement).
Compressible Direct Numerical Simulation of Low-Pressure Turbines: Part I — Methodology (2014)

Modern low pressure turbines (LPT) feature high pressure ratios and moderate Mach and Reynolds numbers, increasing the possibility of laminar boundary-layer separation on the blades. Upstream disturbances including background turbulence and incoming wakes have a profound effect on the behavior of separation bubbles and the type/location of laminar-turbulent transition and therefore need to be considered in LPT design. URANS are often found inadequate to resolve the complex wake dynamics and impact of these environmental parameters on the boundary layers and may not drive the design to the best aerodynamic efficiency. LES can partly improve the accuracy, but has difficulties in predicting boundary layer transition and capturing the delay of laminar separation with varying inlet turbulence levels. Direct Numerical Simulation (DNS) is able to overcome these limitations but has to date been considered too computationally expensive. Here a novel compressible DNS code is presented and validated, promising to make DNS practical for LPT studies. Also, the sensitivity of wake loss coefficient with respect to freestream turbulence levels below 1% is discussed.
The use of the fluorescent probe 8-anilino-1-naphthalene sulphonic acid (ANS) as a histochemical stain in plant tissues (1982)

Abstract. The fluorescent probe 8-anilino-l-naphthalene sulphonic acid (ANS) has been evaluated as a histochemical stain for plant tissues. The wide specificity of the compound for hydrophobic binding sites limits its analytical use, but renders it of considerable value as a general fluorescent stain for use in epi-illumination fluorescence microscopy. Used in this way it is analogous to the light-microscope stain toluidine blue. ANS has also been found to be a sensitive vascular tracer.
Ciprofloxacin concentrations in lung tissue following a single 400 mg intravenous dose (1999)

Intravenous ciprofloxacin is frequently prescribed for the treatment of infections due to nosocomially acquired gram-negative organisms, including those originating in the respiratory tract. In this study, the concentrations of ciprofloxacin in serum and lung tissue were determined by HPLC in patients undergoing lung surgery. A total of 22 patients scheduled for lung surgery received a single 400 mg i.v. dose of ciprofloxacin administered as a 1 h infusion. A specimen of healthy lung tissue was obtained from resected lung from 18 of the patients for analysis of ciprofloxacin concentration during the following time intervals after infusion (one sample/patient): 0-2, 2-4, 4-8 and 8-12 h. Corresponding mean serum and tissue concentrations were 2.37 mg/L and 3.84 mg/kg (0-2 h), 1.18 mg/L and 1.92 mg/kg (2-4 h), 0.69 mg/L and 1.77 mg/kg (4-8 h), and 0.13 mg/L and 0.67 mg/kg (8-12 h). Ciprofloxacin distributed rapidly to lung tissue, as seen by the high concentrations in the lung tissue as early as 2 h after infusion. Concentrations in lung tissue were generally higher than those in serum (tissue:serum ratios ranged from 1.7 to 7.1). The mean tissue concentrations found in this study remained above the MIC for most susceptible organisms.
Cyclooxygenase-2 Is Expressed in Neuroblastoma, and Nonsteroidal Anti-Inflammatory Drugs Induce Apoptosis and Inhibit Tumor Growth <b> <i>In vivo</i> </b> (2004)

Neuroblastoma is the single most common and deadly tumor of childhood and is often associated with therapy resistance. Cyclooxygenases (COXs) catalyze the conversion of arachidonic acid to prostaglandins. COX-2 is up-regulated in several adult epithelial cancers and is linked to proliferation and resistance to apoptosis. We detected COX-2 expression in neuroblastoma primary tumors and cell lines but not in normal adrenal medullas from children. Treatment of neuroblastoma cells with nonsteroidal anti-inflammatory drugs, inhibitors of COX, induced caspase-dependent apoptosis via the intrinsic mitochondrial pathway. Treatment of established neuroblastoma xenografts in nude rats with the dual COX-1/COX-2 inhibitor diclofenac or the COX-2-specific inhibitor celecoxib significantly inhibited tumor growth in vivo (P < 0.001). In vitro, arachidonic acid and diclofenac synergistically induced neuroblastoma cell death. This effect was further pronounced when lipooxygenases were simultaneously inhibited. Proton magnetic resonance spectroscopy ((1)H MRS) of neuroblastoma cells treated with COX inhibitors demonstrated accumulation of polyunsaturated fatty acids and depletion of choline compounds. Thus, (1)H MRS, which can be performed with clinical magnetic resonance scanners, is likely to provide pharmacodynamic markers of neuroblastoma response to COX inhibition. Taken together, these data suggest the use of nonsteroidal anti-inflammatory drugs as a novel adjuvant therapy for children with neuroblastoma.
Table TS4 from A Phase I Trial of VEGF-A Inhibition Combined with PD-L1 Blockade for Recurrent Glioblastoma (2023)

&lt;p&gt;One-way ANOVA analysis comparing expression of cytokines between Avelumab treated and Avelumab combined with Bevacizumab&lt;/p&gt;
Weight-Optimized Bushingless Connecting Rods: Improving the Tribological Performance of a Gudgeon Pin/Connecting Rod System by Using the Triboconditioning® Process (2017)

The risk of failures associated with a distressed pin/connecting rod bearing contact without forced pin oiling is exaggerated due to ever increasing power density and torque output of modern TSI (turbocharged straight injection) and TDI (turbocharged direct injection) engines, in combination with the introduction of low-viscosity low-SAPS (sulfated ash, phosphorus, sulfur) lubricants and general engine downsizing resulting in fewer cylinders to bear the load. This forces OEMs (original equipment manufacturer) to look for innovative cost-efficient solutions to promote bushingless connecting rods without impacting reliability. One such solution is the Triboconditioning process. Triboconditioning is an industrial surface finishing process which attempts to carry out running-in of components during their manufacture. The present paper provides an in-depth analysis of the tribological effects of Triboconditioning on the pin/conrod contact.
Interference in CPFSK optical crossconnect systemswithnoncoherent detection (1994)

In optical crossconnect applications, as the wavelength of a transmitter laser is switched from one channel to another, it may momentarily coincide with wavelengths being used by other transmitter lasers. The resultant interference is assessed experimentally for CPFSK systems with noncoherent detection based on a Fabry-Perot optical filter. It is shown that wavelength switching causes a significant degradation in the bit error ratio performance when direct frequency modulation is used. The influence of the relative states of polarisation of the modulated and switched signals on the switching induced interference is also examined.