gebhart/patrepeval huggingface dataset:
Lipids of gelatinous antarctic zooplankton: Cnidaria and Ctenophora (2000)

Cnidaria (Calycopsis borchgrevinki, Diphyes antarctica, Stygiomedusa gigantea, Atolla wyvillei, Dimophyes arctica) and Ctenophora (Beroe cucumis, B. forskalii, Pleurobrachia pileus, Bolinopsis infundibulum) were collected near Elephant Island, South Shetland Islands, during January and February 1997 and 1998. Total lipid was low in all zooplankton (0.1-5 mg g wet mass) and included primarily polar lipids (59-96% of total lipid). Triacylglycerols were 0-26% of total lipids, and wax esters were 0-11% in all species. Cholesterol was the major sterol in all Cnidaria (50-63% of total sterols) whereas in most ctenophores it was lower at 26-45%. These cholesterol levels are consistent with a combined carnivorous and phytoplanktivorous diet in the ctenophores, with the carnivorous diet more dominant in the Cnidaria. Other sterols included primarily trans-dehydrocholesterol, desmosterol, 24-methylcholest-5,22E-dien-3beta-ol, 24-nordehydrocholesterol, and 24-methylenecholesterol. Total stanols were 0-6% in all zooplankton. Eicosapentaenoic acid and docosahexaenoic acid were the major polyunsaturated fatty acids (PUFA) in all samples (7-25% of total fatty acids) except for A. wyvillei in which docosapentaenoic acid was 10% of total fatty acids. The PUFA 18:5n-3 was not detected in 1997 samples, but constituted 0.2-0.8% in most 1998 samples. Monounsaturated fatty acids included primarily 18:1n-9c, 16:1n-7c, and 18:1n-7c. The principal saturated fatty acids in all samples were 16:0, 18:0, and 14:0. These data are the first for many of these zooplankton species and the first sterol data for most species. The use of the signature lipid approach has enabled examination of aspects of trophodynamics not obtainable by conventional techniques.
Bioreducible poly(amido amine)s with different branching degrees as gene delivery vectors (2012)

Based on the knowledge that cationic polymers with different topographical structures behave differently in gene transfection process, herein, we synthesized three biodegradable poly(amido amine)s (PAAs) with the same repeating units and molecular weights except for degree of branching: linear PAA (LPAA), low-branched PAA (LBPAA), and high-branched PAA (HBPAA). We found that LBPAA could more effectively compact pDNA into positively charged nanoparticles than both HBPAA and LPAA. LBPAA polyplexes had the highest transfection efficiency among the three PAA polyplexes, and the difference in transfection efficiency is mainly attributed to the endocytosis rate. The cytotoxicity of PAAs was negligible at the transfection doses, probably due to the degradable disulfide bonds. Therefore, we could use branching as a parameter to simply tune a polymer's cellular uptake behavior and transfection efficiency.
Garcinol sensitizes human head and neck carcinoma to cisplatin in a xenograft mouse model despite downregulation of proliferative biomarkers (2015)

Platinum compounds such as cisplatin and carboplatin are frequently used as the first-line chemotherapy for the treatment of the head and neck squamous cell carcinoma (HNSCC). In the present study, we investigated whether garcinol, a polyisoprenylated benzophenone can chemosensitize HNSCC to cisplatin. We found that garcinol inhibited the viability of a panel of diverse HNSCC cell lines, enhanced the apoptotic effect of cisplatin, suppressed constitutive as well as cisplatin-induced NF-κB activation, and downregulated the expression of various oncogenic gene products (cyclin D1, Bcl-2, survivin and VEGF). In vivo study showed that administration of garcinol alone (0.5 mg/kg body weight, i.p. five times/week) significantly suppressed the growth of the tumor, and this effect was further increased by cisplatin. Both the markers of proliferation index (Ki-67) and microvessel density (CD31) were downregulated in tumor tissues by the combination of cisplatin and garcinol. The pharmacokinetic results of garcinol indicated that good systemic exposure was achievable after i.p. administration of garcinol at 0.5 mg/kg and 2 mg/kg with mean peak concentration (Cmax) of 1825.4 and 6635.7 nM in the mouse serum, respectively. Overall, our results suggest that garcinol can indeed potentiate the effects of cisplatin by negative regulation of various inflammatory and proliferative biomarkers.
Induction of azoospermia in normal men with combined Nal-Glu gonadotropin-releasing hormone antagonist and testosterone enanthate. (1992)

The effects of a combined GnRH antagonist and testosterone (T) replacement regimen on gonadotropins and spermatogenesis were examined to assess its potential as a male contraceptive regimen. The potent Nal-Glu GnRH antagonist ([Ac-D2-Nal1,D4-Cl-Phe2,D3-Pal3,Arg5, D4-p-methoxybenzoyl-2-amino butyric acid6,D-Ala10]GnRH) was administered daily (7.5 mg, sc) to eight normal men for 16 weeks. T enanthate was given im starting at week 2 and every 2 weeks thereafter through week 14 of the treatment phase. Serum LH, FSH, T, and estradiol concentrations were measured frequently during the 5-week control period, the 16-week treatment phase, and the 14-week recovery phase. Semen analyses were performed every week during the control phase and every 2 weeks during the treatment and recovery phases. Seven of eight subjects became azoospermic by 6-10 weeks of treatment; the eighth subject, who failed to achieve azoospermia, suppressed his sperm count to 7 million/mL by week 14 (from a mean baseline of 42 million/mL) before treatment was prematurely terminated because of localized swelling at each of his injection sites. Sperm counts returned to baseline 10-14 weeks after the end of Nal-Glu administration. Seven of the eight subjects showed suppression of LH to the limit of assay detection (less than 0.2 U/L), whereas the eighth subject showed incomplete suppression. Serum bioactive and immunoreactive LH concentrations showed concordant responses. Mean serum FSH concentrations were also markedly suppressed. Serum T and estradiol concentrations declined dramatically during the first 2 weeks of Nal-Glu GnRH treatment, but returned to the normal physiological range after T enanthate replacement was initiated. Libido and sexual potency were maintained. No systemic side-effects, other than erythema and induration at injection sites, were observed. These data demonstrate that combined GnRH antagonist plus T treatment can predictably and reversibly induce azoospermia in most men and has potential as a male contraceptive regimen.
Oxidation of cinnamyl alcohol using bimetallic Au–Pd/TiO<sub>2</sub> catalysts: a deactivation study in a continuous flow packed bed microreactor (2016)

Deactivation of Au–Pd/TiO<sub>2</sub> catalyst during oxidation in flow is attributed to Pd leaching and a complex effect of oxygen.
Incidência e severidade do vírus do endurecimento dos frutos em maracujazeiros enxertados em pé-franco (2011)

O objetivo deste trabalho foi avaliar a incidência e a severidade do vírus do endurecimento dos frutos em maracujazeiro-amarelo enxertado e pé-franco. O experimento foi conduzido no município de Adamantina-SP, no período de abril de 2006 a junho de 2007, adotando-se o delineamento em blocos ao acaso, com quatro tratamentos e oito repetições. Foram avaliados três porta-enxertos: Passiflora edulis, P. alata e P. gibertii, e plantas de pé-franco. Utilizou-se como copa o maracujazeiro-amarelo (Passiflora edulis Sims). Avaliaram-se a porcentagem de plantas com sintomas de virose e a severidade dos sintomas. As primeiras plantas com sintomas de virose ocorreram aos 90 dias do plantio das mudas no campo, atingindo, aos 180 dias, 100% de plantas com virose em P. alata e P. gibertii, e 97,5% em P. edulis e pé-franco.
Size‐ and Shape‐Controlled Conversion of Tungstate‐Based Inorganic–Organic Hybrid Belts to WO<sub>3</sub> Nanoplates with High Specific Surface Areas (2008)

Two-dimensional monoclinic WO(3) nanoplates with high specific surface areas are synthesized through a novel conversion process using tungstate-based inorganic-organic hybrid micro/nanobelts as precursors. The process developed involves a topochemical transformation of tungstate-based inorganic-organic hybrid belts into WO(3) nanoplates via an intermediate product of H(2)WO(4) nanoplates, utilizing the similarity of the W-O octahedral layers in both H(2)WO(4) and WO(3). The as-obtained WO(3) nanoplates show a single-crystalline nanostructure with the smallest side along the [001] direction. The WO(3) nanoplates are 200-500 nm x 200-500 nm x 10-30 nm in size, and their specific surface areas are up to 180 m(2) g(-1). Photocatalytic measurements of visible-light-driven oxidation of water for O(2) generation in the presence of Ag(+) ions indicate that the activity of the as-obtained WO(3) nanoplates is one order of magnitude higher than that of commercially available WO(3) powders.
Sunflower wax as a New Natural Cosmetic Raw Material: Purification and Application in Lipsticks (2009)

Sunflower Wax is a component of the hull of sunflower (Helianthus annus) oil seeds. The wax is essentially composed of extensively saturated esters of long chain fatty acids (C20-C22) and fatty alcohols (C22-C29). Due to its low economical value, it is often considered as industrial waste. Thus, the focus of the work was to purify the wax and explore its use in cosmetic product, lipstick. The replacement of beeswax with sunflower wax did not alter the properties of the lipstick, thereby providing an economical alternative to beeswax.
Solution and Bulk Structures of Asymmetric PEP-PS-PEP′ Triblock Copolymers (2023)

The self-assembly of four polystyrene (S) and poly(ethylene-alt-propylene) (EP) block copolymers was studied in squalane, an EP-selective solvent. The polymers were prepared by sequential living anionic polymerization of isoprene and styrene, followed by catalytic hydrogenation of the diene block(s). The four polymers had comparable total molar masses (ca. 90 ± 6 kg/mol) and volumetric compositions (fS ≈ 0.25 ± 0.01) but different architectures. Specifically, a diblock SEP(26-70), a symmetric triblock EPSEP(30-24-30), and two asymmetric triblocks EPSEP′(8-26-62) and EPSEP′(15-28-52) were prepared, where the numbers denote block molar masses in kg/mol. Micellization in dilute solution (volume fraction ϕ ≤ 0.01) was studied by dynamic light scattering and small-angle X-ray scattering. All four polymers assembled into spherical micelles, and, as expected, the symmetric triblock formed the smallest particles. The results suggest that the asymmetric triblocks form micelles with a two-layer corona, the inner layer being enriched in the smaller endblock. Upon increasing concentration (ϕ = 0.1 and 0.3), SEP(26-70) and EPSEP(30-24-30) micelles packed onto well-defined body-centered cubic lattices, also as expected. However, surprisingly, the asymmetric triblocks did not adopt a lattice at these volume fractions but rather retained a liquid-like packing. This remarkable effect of architecture was confirmed by linear viscoelastic measurements, which revealed striking differences between the asymmetric triblocks on one hand and the “conventional” architectures on the other. This behavior is speculated to arise from a different inter-micellar potential, stemming from the two-layer corona. At still higher concentrations, all four polymers adopted hexagonal packings, before transitioning to lamellae for ϕ ≥ 0.8.
Indexing for topics in videos using foils (2002)

A long-standing goal of distance learning has been to provide a quality of learning comparable to the face-to-face environment of a traditional classroom for teaching or training. One of the fundamental problems in achieving this goal is providing effective ways of high-level semantic querying such as for the retrieval of relevant learning material relating to a topic of discussion. In this paper we present a method of identifying video segments relating to a topic of discussion by indexing videos using the image and text content of foils. Specifically, we present a novel method of locating and recognizing foil images in video using the color and spatial layout geometry of their regions. We then search the audio associated with video based on the text content of the foil to identify related video segments in which concepts represented on a foil are heard. Finally, we combine the results of foil image and text search of video exploiting their time co-occurrence. The resulting identification of topics is evaluated in the domain of classroom lectures and talks.
Characterization of Pollen-Quantitative, Bromatological and Physicochemical of Honeys Commercialized in Nuevo Leon, Mexico (2019)

Honey is a natural sweet substance produced by bees from plant nectar or secretions from live plant parts or from plant-sucking insect excretions. Bees collect, transform and combine these with their own specific substances and deposit, dehydrate, store and leave them on the hive to mature and age. Mexico is the fourth largest honey producer in the world. Eight honey samples were studied considering aspects palynological, bromatological and physicochemical. Regarding pollen richness, these honeys belong to Class II and III, which correspond to pollen-rich honeys. Regarding moisture, values from 10.55% for S1 honey to 18.14% for LC were found. For ash, LC honey had a lower percentage (0.07%) while EM honey had a greater percentage (0.42%). A maximum protein value of 0.63% was found, corresponding to EC honey. All the honeys analyzed were within the reference values (89.29% for honey S2 and 81.66% for LC) for nitrogen-free extract. Regarding ethereal extract, values of 0.01% and 0.08% were found while water activity (aw) in the honey had values from 0.55 to 0.65. The pH of the honeys was between 3.73 and 4.16. The electrical conductivity of the honeys analyzed was between 0.27 and 0.50 mS/cm. Reducing sugars content was between 63.72 and 84.33%, corresponding to EC and ADA honeys, respectively. The results of this study indicate that the honeys analyzed are within the National and International standards.
Berkeley Chinese Information Retrieval at TREC-5: Technical Report. (1996)

For Chinese track in TREC-5, the collection from the People's Daily and Xinhua News articles includes 164.761 documentss and the volume of the collection is about 170 MB. There are 28 queries. The task of Chinese track is to submit 1000 documents for each query ranked in the order of likelihood of relevance to the query. It is a well known problem that there is no separator between Chinese words so that Chinese words cannot be directly used to index or search text as it is allowes in English. Therefore, people used characters, n-grams, or words as search-able tokens. In TREC-5, we tried to use any meaningful string within text as indexing or search tokens. Our basic strategy is to use an exhaustive dictionary to segment document collection and queries and to use Berkeley TREC2 ad hoc retrieval algorithm to rank retrieved documents
Is Bilateral Internal Thoracic Artery Use Safe in the Elderly? (2011)

Use of BITA is safe in the elderly with respect to mortality and early cardiovascular outcome. BITA use in the elderly is associated with an increased risk of sternal wound infection. Our experience in this situation suggests that there is a maximum age (approximately 74 years) beyond which the combined risk of MACCE and wound complications supersedes the benefits in terms of sternal infections.
Effect of Partial Remelting Procedure on the Microstructural Evolution of 7075 Al Wrought Alloy for Thixoextrusion (2006)

This DOI is not currently attached to any metadata records. DOIs can’t actually ever be deleted (they’re persistent), but sometimes our members create DOIs in error. We do have a process to approximate deletion which we follow only in rare cases where the DOI has been genuinely created in error, and most crucially, if the DOI has never been published anywhere online or in print and never otherwise distributed to or communicated with anyone (authors, readers, reviewers, etc.
DNA Sequencing and Translocation Studies using Electrically Addressable Nanopore Arrays (2005)

Determination of the genetic code embedded in DNA molecules is fundamental to molecular biology and medicine. The most successful technique used for DNA sequencing has been the dideoxy termination mechanism developed by Sanger. Some of the main limitations of the traditional Sanger method are its relatively high cost (it heavily relies on multiple costly polymerase chain reactions), slow speed (the technique relies on gel separations), and only relatively short DNA strands can be effectively sequenced in each gel (600-800 bases). Alternative, faster and lower-cost methods for DNA sequencing are thus in high demand. There is a worldwide race towards a DNA sequencing technology that will cost no more than $1k per human genome. Such a personal genome technology promises to revolutionize medicine. Among the various proposed alternative DNA sequencing technologies, nanopore sequencing, especially with solid-state nanopore devices, is an exciting example. The objective of this NIRT program is to develop the necessary science and technology to bring nanopore DNA sequencing to reality. Our research program [1] brings together broad expertise in nanobioscience, both experimental and theoretical, encompassing solid-state physics to biochemistry, to attack a major problem of
Development and characterization of <scp>Factor Xa</scp>‐responsive materials for applications in cell culture and biologics delivery (2023)

Stimuli-responsive biomaterials may be used to better control the release of bioactive molecules or cells for applications involving drug delivery and controlled cell release. In this study, we developed a Factor Xa (FXa)-responsive biomaterial capable of controlled release of pharmaceutical agents and cells from in vitro culture. FXa-cleavable substrates were formed as hydrogels that degraded in response to FXa enzyme over several hours. Hydrogels were shown to release both heparin and a model protein in response to FXa. Additionally, RGD-functionalized FXa-degradable hydrogels were used to culture mesenchymal stromal cells (MSCs), enabling FXa-mediated cell dissociation from hydrogels in a manner that preserved multicellular structures. Harvesting MSCs using FXa-mediated dissociation did not influence their differentiation capacity or indoleamine 2,3-dioxygenase (IDO) activity (a measure of immunomodulatory capacity). In all, this FXa-degradable hydrogel is a novel responsive biomaterial system that may be used for on-demand drug delivery, as well as for improving processes for in vitro culture of therapeutic cells.
New construction of clarifying tun. (1992)

Pro scezovĂĄnĂ­ sladiny byla vyvinuta modernĂ­ scezovacĂ­ kĂĄd' s nĂĄtokern spodem a kypĹicĂ­m zaĹĂ­zenĂ­m s dvojitĂ˝mi vlnitĂ˝mi noĹži a centrĂĄlnĂ­m systĂŠmem scezovĂĄnĂ­. Je porovnĂĄna hodnota zĂĄkalu a obsahu O2 ve sladinÄ u novĂŠ scezovacĂ­ kĂĄdÄ a kĂĄdÄ se starĂ˝m nĂĄtokem shora.
Low power voltage reference architectures (2009)

In this paper, we present 3 novel methods for generating voltage references. The first architecture focuses on low voltage high precision voltage reference reducing the variation to 5mV from 105mV across temperature of -40 to 100degC. The second architecture focuses on low voltage low power reference bringing down current consumption to half. The third one is a hybrid architecture with lesser voltage reference variation and lesser power consumption but has higher operational voltage.
Obituary for Robert G. Addison, MD (2012)

Gifted physician, surgeon, researcher, teacher and sculptor Robert George Addison died peacefully with his wife Beverly at his side, surrounded by family in Bradenton, Florida, on March 15, 2012. He was 90.

Dr. Robert G. Addison served at the Northwestern University Medical School since 1953 as clinical professor in the Department of Orthopaedic Surgery and later, in the Department of Physical Medicine & Rehabilitation. Dr. Addison maintained an active private practice as an orthopedic surgeon until joining the Rehabilitation Institute of Chicago as a full-time staff member in 1974. At the Rehabilitation Institute of Chicago (RIC), Dr. Addison has served as medical director, chief of …
B(C<sub>6</sub>F<sub>5</sub>)<sub>3</sub>-Catalyzed Hydrosilylation of Vinylcyclopropanes (2020)

A hydrosilylation of vinylcyclopropanes (VCPs) catalyzed by the strong boron Lewis acid B(C<sub>6</sub>F<sub>5</sub>)<sub>3</sub> is reported. For the majority of VCPs, little or no ring opening of the cyclopropyl unit is observed. Conversely, for VCPs with bulky R groups, such as ortho-substituted aryl rings or branched alkyl residues, ring opening is the exclusive reaction pathway. This finding is explained by the thwarted hydride delivery to a sterically shielded, β-silicon-stabilized cyclopropylcarbinyl cation intermediate.
Robotic Kinematic measures of the arm in chronic Stroke: part 2 – strong correlation with clinical outcome measures (2021)

http://www.clinicaltrials.gov . Actual study start date September 2012. First registered on 15 November 2012. Retrospectively registered. Unique identifiers: NCT01726673 and NCT03562663 .
Skull base Osteomyelitis: challenges and Therapy outcomes. (2020)

Objective Skull base Osteomyelitis is a rare but life threatening condition. It mostly arises as a complication of malignant otitis externa. It presents commonly in elderly patients with poorly managed Diabetes mellitus, and immunocompromised patients. The aim of the study is to evaluate the recent Therapy options.
Novel Eco-Synthesis of PD Silver Nanoparticles: Characterization, Assessment of Its Antimicrobial and Cytotoxicity Properties (2019)

Nanomedicine is growing due to the development of new medical diagnostic tools and new nanostructure-based therapies that exert direct biological action or function as pharmacological carriers. Nanoparticles (NPs) synthesis provides an eco-friendly approach for different applications. Among NPs, silver NPs (AgNPs) are gaining considerable research interest due to their broad range of activity and their usability in the medical and biotechnology fields. In this study, a new AgNP synthesis method was developed using an aqueous pigeon dropping (PD) extract in silver nitrate (AgNO<sub>3</sub>). The rapid of AgNPs yield was detected visually. Analysis of UV-vis spectroscopy, energy-dispersive X-ray spectroscopy (EDX), dynamic light scattering (DLS) and electron microscopy (TEM) transmission showed a spherical or near spherical shape of AgNPs with mean size of 135 nm. AgNPs antimicrobial activities (anti-bacterial and anti-fungal) were determined using agar well diffusion method. These NPs further screened for anticancer activity in vitro using A-549 and MCF-7 cell lines. The results showed that the inhibition zone for the obtained PD AgNPs versus <i>Escherichia coli</i>, <i>Pseudomonas aeruginosa</i>, <i>Staphylococcus aureus</i>, and <i>Bacillus</i> were 26, 18, 17 and 15 mm, respectively. PD AgNPs showed the highest antifungal effect against <i>Aspergillus</i> <i>flavus</i> and the lowest effect against <i>Penicillium griseofulvum</i>. In vitro anti-cancer activities showed that the inhibitory concentration of 50% (IC<sub>50</sub>) of AgNPs was 10.3 ± 1.15 and 12.19 ± 0.75 µg mL<sup>-1</sup> against A-549 and MCF-7 cancer cell lines, respectively.