gebhart/patrepeval huggingface dataset:
Oil-degrading bacterial consortium from Gulf of Mexico designed by a factorial method, reveals stable population dynamics (2022)

We describe an assembled marine bacterial consortium designed for bioremediation of oil-contaminated seawater, based on a statistical method using a Plackett-Burman (PB) experimental approach. The final consortium consists of four bacteria isolated from the Gulf of Mexico, from four genera: Pseudomonas, Halopseudomonas, Paenarthrobacter , and Alcanivorax . Individually, bacterial oil removal by these microorganisms was evaluated by gravimetry, reaching 39% at maximum after 75 days, whereas in consortium it was ~62%. We also measured biodegradation levels by Gas Chromatography/Mass Spectrometry (GC-MS) observing 12 polyaromatic hydrocarbons (PAHs) degradation analyzed and n -alkanes degradation with a preference for specific chain length. Consortium population analysis using the V3-V4 region of 16S rRNA showed a stable community, suggesting that the metabolic load was distributed among bacteria and that stable dynamic interactions were achieved. In this work, we show that the use of a factorial method for synthetic consortium design offers the possibility of improving oil degradation efficiency with stable bacterial populations.
ISWP Caster Test Version 2.2 (2018)

This document contains the assembly instructions, electrical wiring information, component manuals, bill of materials, and part drawings required for building the ISWP Caster Test equipment.
Notas Científicas Transmisión del Mal de Río Cuarto virus por ninfas de primer y tercer estadio de Delphacodes kuscheli (2005)

The ability of first and third-instar Delphacodes kuscheli Fennah (Hemiptera: Delphacidae) nymphs to acquire and transmit Mal de Rio Cuarto virus (MRCV), under controlled conditions, was investigated. First and third-instar nymphs were allowed acquisition feeding separately on infected wheat plants for 48 hours. The insects were then placed in groups of three for serial transmissions to healthy wheat plants, using inoculation periods of 24 hours. Both instars of D. kuscheli were demonstrated to acquire and subsequently transmit the virus. Nevertheless, transmission trials showed highest transmission efficiency and shortest latent period when MRCV was acquired by first-instar nymphs.
In Vitro Effect of Anticardiolipin Autoantibodies Upon Total and Pulsatile Placental hCG Secretion During Early Pregnancy (1993)

These studies with placental explants show that ACA may have an additional effect on placental hormone secretion and thus affect the fate of the embryo.
Synthesis and IR, UV, NMR (1H and 11B), and mass spectral studies of new .beta.-ketoamine complexes of boron: crystal an molecular structure of OC6H4OBOC(R)CHC(R')NR" (R = p-ClC6H4, R' = C6H5, R" = CH3) (1986)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSynthesis and IR, UV, NMR (1H and 11B), and mass spectral studies of new .beta.-ketoamine complexes of boron: crystal an molecular structure of OC6H4OBOC(R)CHC(R')NR" (R = p-ClC6H4, R' = C6H5, R" = CH3)Yash P. Singh, P. Rupani, Anirudh Singh, Audhesh K. Rai, Ram C. Mehrotra, Robin D. Rogers, and Jerry L. AtwoodCite this: Inorg. Chem. 1986, 25, 17, 3076–3081Publication Date (Print):August 1, 1986Publication History Published online1 May 2002Published inissue 1 August 1986https://pubs.acs.org/doi/10.1021/ic00237a030https://doi.org/10.1021/ic00237a030research-articleACS PublicationsRequest reuse permissionsArticle Views215Altmetric-Citations29LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
Fitness of twospotted spider mites is more affected by constitutive than induced resistance traits in cotton (<i>Gossypium</i> spp.) (2013)

Following publication of the above article (DOI 10.1002/ps.3546) on Wiley Online Library on 17 June 2013 and in the present issue of Pest Management Science (69:1187-1197), the following mistake was found: On page 1195, last paragraph of the first column, one reads: “Leaf thickness is also a morphological trait which can influence mite resistance. The leaves of the two resistant genotypes, BM13H (approx. 280 m) and Sipima 280 (approx. 270 m), were thinner than Sicot 71 (approx. 330 m) grown in the field (Miyazaki J, unpublished). However, the lower epidermis, which is the distance between the underside of the leaf surface and the spongy mesophyll cell layer, was approximately 17.5 m on all three genotypes. Thus, these three genotypes had the same distance for mites to feed on the contents of spongy mesophyll cells.” This should read: “Leaf thickness is also a morphological trait which can influence mite resistance. The leaves of the two resistant genotypes, BM13H (approx. 280 µm) and Sipima 280 (approx. 270 µm), were thinner than Sicot 71 (approx. 330 µm) grown in the field (Miyazaki J, unpublished). However, the lower epidermis, which is the distance between the underside of the leaf surface and the spongy mesophyll cell layer, was approximately 17.5 µm on all three genotypes. Thus, these three genotypes had the same distance for mites to feed on the contents of spongy mesophyll cells.”
Triterpenoid production with a minimally engineered <i>Saccharomyces cerevisiae</i> chassis (2022)

Abstract Triterpenoids, one of the most diverse classes of natural products, have been used for centuries as active ingredients in essential oils and Chinese medicines and are of interest for many industrial applications ranging from low-calorie sweeteners to cosmetic ingredients and vaccine adjuvants. However, not only can the extraction from plant material be cumbersome due to low concentrations of the specific triterpenoid, but concerns are also increasing regarding the sustainability of wild plant harvest while meeting market demands. The alternative is to produce triterpenoids with engineered microbes. Here, we present a generally applicable strategy for triterpenoid production in the yeast Saccharomyces cerevisiae based on a modified oxidosqualene cyclase Erg7. The modification reduces the flux into the sterol pathway while increasing the precursor supply for triterpenoid production. The minimally engineered strain was exploited for the exemplary production of the lupane triterpenoids betulin, betulin aldehyde, and betulinic acid at a total titer above 6 g/L, the highest reported so far. To further highlight the chassis concept, squalene, oleanane- and dammarane-type triterpenoids were synthesized to titers at a similar gram scale. We propose the developed baker’s yeast as a host for the thousands of triterpenoid synthesis pathways from plants, reducing the pressure on the natural resources.
Self-heated fiber Bragg grating sensors for cryogenic environments (2010)

Cryogenic fuels are often considered as major energy alternatives to coal and petroleum based fuels. Safe and reliable sensor networks are required for on-demand, real-time fuel management in cryogenic environments. In this paper, a new sensor design is described that enhances the low-temperature performance of fiber sensors. FBGs inscribed in high attenuation fiber (HAF) are used to absorb in-fiber power light to raise the local sensor temperature in the cryogenic environment. When in-fiber power light is turned off, FBG sensors can serve as passive sensors to gauge temperature and stress in the cryogenic system. When the in-fiber power light is turned on, the heated sensors can be used to rapidly gauge fuel level and fuel leaks. In one example, a hydrogen gas sensor is demonstrated with a palladium-coated fiber Bragg grating (FBG). The low-temperature performance of the sensor was improved by heating the gratings as much as 200 K above the ambient temperature, and hydrogen concentration well below the 4% explosion limit was measured at 123K. In a second example, an array of four aluminum coated fiber Bragg gratings was used to measure liquid level in a cryogenic environment.
Muscle-Specific Deletion of the Glut4 Glucose Transporter Alters Multiple Regulatory Steps in Glycogen Metabolism (2005)

Mice with muscle-specific knockout of the Glut4 glucose transporter (muscle-G4KO) are insulin resistant and mildly diabetic. Here we show that despite markedly reduced glucose transport in muscle, muscle glycogen content in the fasted state is increased. We sought to determine the mechanism(s). Basal glycogen synthase activity is increased by 34% and glycogen phosphorylase activity is decreased by 17% (P < 0.05) in muscle of muscle-G4KO mice. Contraction-induced glycogen breakdown is normal. The increased glycogen synthase activity occurs in spite of decreased signaling through the insulin receptor substrate 1 (IRS-1)-phosphoinositide (PI) 3-kinase-Akt pathway and increased glycogen synthase kinase 3beta (GSK3beta) activity in the basal state. Hexokinase II is increased, leading to an approximately twofold increase in glucose-6-phosphate levels. In addition, the levels of two scaffolding proteins that are glycogen-targeting subunits of protein phosphatase 1 (PP1), the muscle-specific regulatory subunit (RGL) and the protein targeting to glycogen (PTG), are strikingly increased by 3.2- to 4.2-fold in muscle of muscle-G4KO mice compared to wild-type mice. The catalytic activity of PP1, which dephosphorylates and activates glycogen synthase, is also increased. This dominates over the GSK3 effects, since glycogen synthase phosphorylation on the GSK3-regulated site is decreased. Thus, the markedly reduced glucose transport in muscle results in increased glycogen synthase activity due to increased hexokinase II, glucose-6-phosphate, and RGL and PTG levels and enhanced PP1 activity. This, combined with decreased glycogen phosphorylase activity, results in increased glycogen content in muscle in the fasted state when glucose transport is reduced.
Octagonal Large-Mode-Area Leakage Channel Fiber with Reduced Bending Loss (2010)

We investigate a novel design for high-power large-mode-area leakage channel fibers (LCFs) with a single octagonal dual-diameter air-hole ring encircling a nine-cell pure-silica core, having a tenfold differential mode loss and increased resistance to bending.
Photoswitchable microtubule stabilisers optically control tubulin cytoskeleton structure and function (2019)

ABSTRACT Small molecule inhibitors provide a versatile method for studies in microtubule cytoskeleton research, since tubulin is not readily amenable to functional control using genetics. However, traditional chemical inhibitors do not allow spatiotemporally precise applications on the length and time scales appropriate for selectively modulating microtubule-dependent processes. We have synthesised a panel of taxane-based light-responsive microtubule stabilisers, whose tubulin hyperpolymerisation activity can be induced by photoisomerisation to their thermodynamically metastable state. These reagents can be isomerised in live cells, optically controlling microtubule network integrity, cell cycle repartition, and cell survival, and offering biological response on the timescale of seconds and spatial precision to the level of individual cells. These azobenzene-based microtubule stabilisers offer the possibility of noninvasive, highly spatiotemporally precise modulation of the microtubule cytoskeleton in live cells, and can prove powerful reagents for studies of intracellular transport, cell motility, and neurodegeneration. Abstract Figure
A framework for process management in service oriented virtual organizations (2011)

Virtual Organization (VO) is a network of autonomous organizations sharing their competitive advantage to address a specific business opportunity. Due to their autonomous and interdependent nature, management of collaboration among such organizations is a challenging task. In this paper, we present a framework for process management in service oriented virtual organizations. We propose 6 layers for the framework with multiple components within each layer. In designing the components of the framework, standard reference architecture such as Open-EDI reference model and the S3 service oriented architecture, as well as best practices such as ITIL V3 and PMBOK are used. Further, we present a distributed SOA infrastructure that facilitates peer-to-peer collaboration between organizations in a virtual organization. The infrastructure is based on creating specific service zone for each participating organization to build a virtual ESB. Compared to collaborative environment in networked organization usually supported by computer networks, the loose coupling of services, and the autonomous characteristics of service oriented architecture make it one the best approaches for implementing virtual organization.
Hair Metabolomics: Identification of Fetal Compromise Provides Proof of Concept for Biomarker Discovery (2014)

Analysis of the human metabolome has yielded valuable insights into health, disease and toxicity. However, the metabolic profile of complex biological fluids such as blood is highly dynamic and this has limited the discovery of robust biomarkers. Hair grows relatively slowly, and both endogenous compounds and environmental exposures are incorporated from blood into hair during growth, which reflects the average chemical composition over several months. We used hair samples to study the metabolite profiles of women with pregnancies complicated by fetal growth restriction (FGR) and healthy matched controls. We report the use of GC-MS metabolite profiling of hair samples for biomarker discovery. Unsupervised statistical analysis showed complete discrimination of FGR from controls based on hair composition alone. A predictive model combining 5 metabolites produced an area under the receiver-operating curve of 0.998. This is the first study of the metabolome of human hair and demonstrates that this biological material contains robust biomarkers, which may lead to the development of a sensitive diagnostic tool for FGR, and perhaps more importantly, to stable biomarkers for a range of other diseases.
Jet impingement modeling of cryogen spray cooling: analysis of 2D cryogen temperature distribution (2001)

The main goal of this study was to demonstrate the feasibility of using backside infrared imaging to estimate the spatial cryogen temperature distribution during a cryogen spurt. Calculations from numerical models showed that the frontside temperature distribution could be identified at the back side of a thin aluminum sheet. Infrared images were obtained at various timepoints during a cryogen spurt from the back side of an 800-micrometers aluminum sheet and the temperature distribution estimated. The temperature distribution was approximately gaussian in shape. A secondary goal was to calculate the temperature distribution in skin for two cases: 1) uniform cryogen temperature distribution, essentially representative of a 1D geometry assumption; and 2) nonuniform distribution. At the end of a 100-ms spurt, calculations showed that, for the two cases, large discrepancies in temperatures at the surface and at a 60-micrometers depth were found at radii greater than 2.5 mm. These results suggest that it is necessary to consider spatial cryogen temperature gradients during cryogen spray cooling of tissue.
Pancreas preservation: clinical practice and future developments (2020)

The storm of new organ preservation methods is now being more widely studied in the pancreas, with some promising results. These new strategies have the potential to allow expansion of the donor pool and greater utilization of ECD and DCD organs.
Asynchronous repetitive control of switched systems via periodic event-based dynamic output feedback (2019)

Abstract This paper develops an asynchronous mode-dependent repetitive control strategy with periodic event-based dynamic output feedback for periodic trajectory tracking of continuous-time switched systems subject to time-varying switching delays between system modes and controllers and limited communication capacity in the feedback channel. By employing the input delay approach, the overall system is modelled as an augmented closed-loop switched system with both constant and time-varying state delays. A co-design framework is proposed for simultaneously designing the controller, event-triggering mechanism and mode switching signal. Under the co-design framework, using piecewise Lyapunov functional, free-weighting matrices and average dwell time technique, sufficient conditions are derived for ensuring the augmented closed-loop system to be exponentially stable with a prescribed $H_{\infty }$ attenuation level $\gamma $ for an exogenous disturbance input. The performance of the proposed controller design scheme is verified via numerical simulation results on a switched RLC series circuit system.
A Study on Trouble and Arrangement of the Ground-Fault Protection for 2 Step Voltage Distribution System of Premises (2010)

Most accidents occurred in power receiving & transforming facility are ground fault. The quality of power supply is deteriorated since the ground fault is not detected promptly. This paper analyzes the problems about system-grounding type of 2 step power receiving & transforming facility, arrangement of protection relaying scheme and ground-fault protection system of ungrounded system. Then, this paper presents the arranging scheme of system-grounding type to improve power supply reliability.
Fusobacterium nucleatum‐mediated immunomodulation of the in vitro secondary antibody response to tetanus toxoid and Actinobacillus actinomycetemcomitans (1987)

The present study was undertaken to determine if one of the most prevalent periodontitis‐associated organisms, Fusobacterium nucleatum (F. NUC), was capable of modulating secondary immune responses, including responses against Actinobacillus actinomycetemcomitans (AA). Peripheral blood lymphocytes (PBLs) were obtained from individuals known to have high serum antibody against Tetanus toxoid (TT) or AA. The addition of either TT, sonicated F.NUC, or pokeweed mitogen (PWM) to PBLs from subjects with high anti‐TT titers stimulated production of anti‐TT in vitro. However, the addtion of TT in combination with either F.NUC or PWM resulted in dramatic enhancement of anti‐TT production over antigen or nonspecific activator alone. Similarly, an in vitro secondary response could be induced with antigen from AA, and the addition of F.NUC likewise showed a marked immunoadjuvant effect. The data indicate that F.NUC has potent immunomodulatory activity. The high titers of locally produced specific antibody in gingival crevicular fluid to AA and certain other periodontitis‐associated bacteria may result from the combined effect of specific antigen together with an immunomodulator of bacterial origin.
LADTAP-PROB: A PROBABILISTIC MODEL TO ASSESS RADIOLOGICAL CONSEQUENCES FROM LIQUID RADIOACTIVE RELEASES (2009)

The potential radiological consequences to humans resulting from aqueous releases at the Savannah River Site (SRS) have usually been assessed using the computer code LADTAP or deterministic variations of this code. The advancement of LADTAP over the years included LADTAP II (a computer program that still resides on the mainframe at SRS) [1], LADTAP XL{copyright} (Microsoft Excel{reg_sign} Spreadsheet) [2], and other versions specific to SRS areas such as [3]. The spreadsheet variations of LADTAP contain two worksheets: LADTAP and IRRIDOSE. The LADTAP worksheet estimates dose for environmental pathways including ingestion of water and fish and external exposure resulting from recreational activities. IRRIDOSE estimates potential dose to individuals from irrigation of food crops with contaminated water. A new version of this deterministic methodology, LADTAP-PROB, was developed at Savannah River National Laboratory (SRNL) to (1) consider the complete range of the model parameter values (not just maximum or mean values), (2) determine the influences of parameter uncertainties within the LADTAP methodology, to perform a sensitivity analysis of all model parameters (to identify the input parameters to which model results are most sensitive), and (3) probabilistically assess radiological consequences from contaminated water. This study presents the methodology applied in LADTAP-PROB.
Fresh and cryopreserved ovarian tissue from deceased young donors yields viable follicles (2021)

Our results indicate the ovarian tissue from deceased donors maintain high quality after long time extracorporeal circulation and transportation from the hospital to the laboratory. High survival rate of follicles at different developmental stages suggested tolerance to the cryopreservation process. Human ovarian tissues obtained from deceased donors is an ample source tissue and can be applied to promoting research and future clinical applications.
The Studies on the Porcelain Laminate Veneers. The Adhesion between Porcelain and Enamel under Various Conditions. (1992)

The adhesiveness between the porcelain and the etched enamel was studied under the various conditions. The porcelain surface was treated with Laminabond porcelain primer or Clapearl bonding agent, then adhered to the etched enamel mediated with Laminabond composite paste or Clapearl DC. The resin thickness was 150 or 400 μm, and the irradiation time was 120s or 240s. The shear bond strengths were measured after one day immersion in 37°C water and after10, 000 thermocycles between 4°C and 60°C.When resin thickness was 150 μm, the little decrease of the bond strengths after thermocycles was observed. While in the case of 400 μm resin thickness, the high and durable adhesion between the masking porcelain and the etched enamel was obtained with the use of Clapearl bonding agent and Clapearl DC, or with 240 s photo irradiation.The polymerization of the cemented resin was an important role in the adhesionbetween the porcelain and the etched enamel.
Production of ω-3 Polyunsaturated Fatty Acids From Cull Potato Using an Algae Culture Process (2007)

Algal cultivation for converting cull potato to docosahexaenoic acid (DHA) was studied. Schizochytrium limacinum SR21 was selected as the better producing strain, compared with Thraustochytrium aureum because of higher cell density and DHA content. Used as both carbon and nitrogen source, an optimal ratio of hydrolyzed potato broth in the culture medium was determined as 50%, with which the highest production of 21.7 g/L dry algae biomass and 5.35 g/L DHA was obtained, with extra glucose supplemented. Repeat culture further improved the cell density but not fed batch culture, suggesting limited growth was most likely caused by metabolites inhibition.