gebhart/patrepeval huggingface dataset:
A flexible ASIP architecture for connected components labeling in embedded vision applications (2014)

Real-time identification of connected regions of pixels in large (e.g. FullHD) frames is a mandatory and expensive step in many computer vision applications that are becoming increasingly popular in embedded mobile devices such as smart-phones, tablets and head mounted devices. Standard off-the-shelf embedded processors are not yet able to cope with the performance/flexibility trade-offs required by such applications. Therefore, in this work we present an Application Specific Instruction Set Processor (ASIP) tailored to concurrently execute thresholding, connected components labeling and basic feature extraction of image frames. The proposed architecture is capable to cope with frame complexities ranging from QCIF to FullHD frames with 1 to 4 bytes-per-pixel formats, while achieving an average frame rate of 30 frames-per-second (fps). Synthesis was performed for a standard 65nm CMOS library, obtaining an operating frequency of 350MHz and 2.1mm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> area. Moreover, evaluations were conducted both on typical and synthetic data sets, in order to thoroughly assess the achievable performance. Finally, an entire planar-marker based augmented reality application was developed and simulated for the ASIP.
Pulse-shaped offset QAM in discrete-time (2010)

Contrary to multicarrier modulation (MCM), single carrier (SC) can provide low peak to average power ratios (PAPRs). Thus, they have been proposed for various mobile systems, e.g. for the GSM and for the 3GPP-LTE. In this paper, we use the link with a MCM system to introduce a SC transceiver based on the Offset Quadrature Amplitude Modulation (OQAM). We show that, for certain systems, OQAM can provide simultaneously orthogonality and phase linearity properties that cannot be reached by conventional QAM schemes. Furthermore, we get improvements with respect to the power ratio (PR).
Comparison of Dose–Response Relationships for Two Isolates of SARS-CoV-2 in a Nonhuman Primate Model of Inhalational COVID-19 (2022)

<b><i>Background:</i></b> As the COVID-19 pandemic has progressed, numerous variants of SARS-CoV-2 have arisen, with several displaying increased transmissibility. <b><i>Methods:</i></b> The present study compared dose-response relationships and disease presentation in nonhuman primates infected with aerosols containing an isolate of the Gamma variant of SARS-CoV-2 to the results of our previous study with the earlier WA-1 isolate of SARS-CoV-2. <b><i>Results:</i></b> Disease in Gamma-infected animals was mild, characterized by dose-dependent fever and oronasal shedding of virus. Differences were observed in shedding in the upper respiratory tract between Gamma- and WA-1-infected animals that have the potential to influence disease transmission. Specifically, the estimated median doses for shedding of viral RNA or infectious virus in nasal swabs were approximately 10-fold lower for the Gamma variant than the WA-1 isolate. Given that the median doses for fever were similar, this suggests that there is a greater difference between the median doses for viral shedding and fever for Gamma than for WA-1 and potentially an increased range of doses for Gamma over which asymptomatic shedding and disease transmission are possible. <b><i>Conclusions:</i></b> These results complement those of previous studies, which suggested that differences in exposure dose may help to explain the range of clinical disease presentations observed in individuals with COVID-19, highlighting the importance of public health measures designed to limit exposure dose, such as masking and social distancing. The dose-response data provided by this study are important to inform disease transmission and hazard modeling, as well as to inform dose selection in future studies examining the efficacy of therapeutics and vaccines in animal models of inhalational COVID-19.
Ectopic Expression of Bovine Type 5 Phosphodiesterase Confers a Renal Phenotype in Drosophila (2004)

cGMP signaling regulates epithelial fluid transport by Drosophila Malpighian (renal) tubules. In order to directly evaluate the importance of cGMP-degrading phosphodiesterases (PDEs) in epithelial transport, bovine PDE5 (a bona fide cGMP-PDE), was ectopically expressed in vivo. Transgenic UAS-PDE5 Drosophila were generated, and PDE5 expression was driven in specified tubule cells in vivo by cell-specific GAL4 drivers. Targeted expression was verified by PCR and Western blotting. Immunolocalization of PDE5 in tubule confirmed specificity of expression and demonstrated localization to the apical plasma membrane. GAL4/UAS-PDE5 tubules exhibit increased cG-PDE activity and reduced basal cGMP levels compared with control lines. We show that wild-type and control tubules are sensitive to the PDE5-specific inhibitor sildenafil and that GAL4/UAS-PDE5 tubules display enhanced sensitivity to sildenafil, compared with controls. cGMP content in GAL4/UAS-PDE5 tubules is restored to control levels by treatment with sildenafil. Thus bovine PDE5 retains cGMP-degrading activity and inhibitor sensitivity when expressed in Drosophila. Expression of PDE5 in tubule principal cells results in an epithelial phenotype, reducing rates of basal and cGMP-/Cardioaccelatory peptide(2b)(CAP(2b))-stimulated fluid transport. Furthermore, inhibition of PDE5 activity by sildenafil restores basal and cGMP-stimulated fluid transport rates to control levels. However, corticotrophin releasing factor-like-stimulated transport, which is activated by cAMP signaling, was unaffected, confirming that only cGMP-stimulated signaling events in tubule are compromised by overexpression of PDE5. Successful ectopic expression of a vertebrate cG-PDE in Drosophila has shown that cG-PDE has a critical role in tubule function in vivo and that cG-PDE function is conserved across evolution. The transgene also provides a generic tool for the analysis of cGMP signaling in Drosophila.
Pore‐scale measurements of solute breakthrough using microfocus X‐ray computed tomography (2000)

X‐ray computed tomography (CT) offers distinct advantages to study fundamental physical processes of water movement and contaminant transport in porous media. Tomography provides nondestructive and noninvasive cross‐sectional or three‐dimensional representations of porous media and has the potential to measure phase distribution and species concentration at the pore scale. Sources of error are discussed for the application of industrial microfocus CT to quantitative studies of flow and transport. Specifically, effective resolution and measurement uncertainties due to photon randomness are considered for a miscible displacement experiment. A calibration method for the measurement of solute concentration is proposed that accounts for the effect of beam hardening, which is characteristic for polychromatic industrial X‐ray sources. The results of an X‐ray microfocus CT experiment are presented, emphasizing the need to correct for beam hardening and describing the inherent spatial variability of solute breakthrough through a glass‐bead porous medium with an effective spatial resolution of approximately 85 μm.
Hardware-Assisted Feature Analysis and Visualization of Procedurally Encoded Multifield Volumetric Data (2005)

We take a new approach to interactive visualization and feature detection of large scalar, vector, and multifield computational fluid dynamics data sets that is also well suited for meshless CFD methods. Radial basis functions (RBFs) are used to procedurally encode both scattered and irregular gridded scalar data sets. The RBF encoding creates a complete, unified, functional representation of the scalar field throughout 3D space, independent of the underlying data topology, and eliminates the need for the original data grid during visualization. The capability of commodity PC graphics hardware to accelerate the reconstruction and rendering and to perform feature detection from this functional representation is a powerful tool for visualizing procedurally encoded volumes. Our RBF encoding and GPU-accelerated reconstruction, feature detection, and visualization tool provides a flexible system for visually exploring and analyzing large, structured, scattered, and unstructured scalar, vector, and multifield data sets at interactive rates on desktop PCs.
Axial magnetic field interrupters in autorecloser applications (2002)

Application of vacuum interruption in distribution switchgear, especially in autoreclosers, which have uniquely high demands on vacuum fault interrupters, are discussed. The fast open-close-open sequence and its associated highly asymmetrical waveforms are some of the difficulties encountered. The authors present their solution to these problems in the form of an economical axial magnetic field interrupter that realizes current densities of up to 1.68 kA/cm/sup 2/-the most efficient axial magnetic interrupter that is in production today. Actual design test data per ANSI C37.60 is shown.
Incremental Redundancy, Fountain Codes and Advanced Topics (2014)

This document is written in order to establish a common base ground on which the majority of the relevant research about linear fountain codes can be analyzed and compared. As far as I am concerned, there is no unified approach that outlines and compares most of the published linear fountain codes in a single and self-contained framework. This written document has not only resulted in the review of theoretical fundamentals of efficient coding techniques for incremental redundancy and linear fountain coding, but also helped me have a comprehensive reference document and hopefully for many other graduate students who would like to have some background to pursue a research career regarding fountain codes and their various applications. Some background in information, coding, graph and probability theory is expected. Although various aspects of this topic and many other relevant research are deliberately left out, I still hope that this document shall serve researchers' need well. I have also included several exercises to warm up. The presentation style is usually informal and the presented material is not necessarily rigorous. There are many spots in the text that are product of my coauthors and myself, although some of which have not been published yet.
Radio signal strength tracking and control for robotic networks (2011)

Radio signal strength (RSS) is a reasonable proxy for link quality, but its accurate estimation requires frequency and spatial diversity due to fluctuation caused by fading. We consider a Rayleigh/Rician fading model, and gather RSS measurements during motion in a complex environment to enable gradient estimation. Using the RSS gradient, we develop control laws to track active sources. These may be used to establish and preserve connectivity among collaborative autonomous agents, to locate and approach radio sources, as well as deploying agents to assist mobile ad hoc networks (MANETs).
Cell-Penetrating Peptide-Modified Gold Nanoparticles for the Delivery of Doxorubicin to Brain Metastatic Breast Cancer (2016)

As therapies continue to increase the lifespan of patients with breast cancer, the incidence of brain metastases has steadily increased, affecting a significant number of patients with metastatic disease. However, a major barrier toward treating these lesions is the inability of therapeutics to penetrate into the central nervous system and accumulate within intracranial tumor sites. In this study, we designed a cell-penetrating gold nanoparticle platform to increase drug delivery to brain metastatic breast cancer cells. TAT peptide-modified gold nanoparticles carrying doxorubicin led to improved cytotoxicity toward two brain metastatic breast cancer cell lines with a decrease in the IC50 of at least 80% compared to free drug. Intravenous administration of these particles led to extensive accumulation of particles throughout diffuse intracranial metastatic microsatellites with cleaved caspase-3 activity corresponding to tumor foci. Furthermore, intratumoral administration of these particles improved survival in an intracranial MDA-MB-231-Br xenograft mouse model. Our results demonstrate the promising application of gold nanoparticles for improving drug delivery in the context of brain metastatic breast cancer.
Structural Characterization of Monolayers at the air–water interface (1991)

Review: X‐Ray diffraction, fluorescence microscopy, and reflection spectroscopy , are all methods used for the characterization of organic thin films which enable the study of, for example, dipole layers, domain structures, mechanical surface excitations, and the orientation of the hydrocarbon ‘tails’. The methods and their applications, especially in the optimization of monolayer formation and transfer, are reviewed.
Epididymal proteome, transcriptome, what else (2010)

International audience
Photoinduced electron transfer at the polymer‐solution interface. I. Surface property‐reactivity relation (1983)

Abstract Photooxidation of leuco crystal violet(LCV) to the dye(CV + ) by interfacial sensitization with polymer‐bonded pyrenyl groups was studied. Poly(ethylene‐ g ‐acrylic acid) was esterified by 1‐hydroxymethylpyrene in tetrahydrofuran (THF) (Film 1) or in acetonitrile (Film 2). Film 2 had a more condensed but thinner pyrene‐containing surface layer than Film 1. Differences in surface structure were investigated by fluorescence and absorption spectra, as well as by measuring contant angle to water as a function of the total amount of bonded pyrene. Films 1 and 2 behaved differently in the photoreaction, which was interpreted as due to the difference in the affinity of LCV solution to the film surface, hence the diffusion of LCV into the film. The quantum efficiency of CV + formation (ϕcv + ) is therefore the function of the thickness of the photoabsorbing layer and the effective reaction volume determined by the depth of LCV diffusion. The role of excimer formation and energy migration among pyrenyl groups was concluded to be of minor importance.
Spontaneous Rupture of the Right Gastroepiploic Artery Immediately after Gastroscopy (2021)

Idiopathic spontaneous intraperitoneal hemorrhage is both rare and potentially fatal. The incidence of gastroepiploic artery rupture, especially a non-aneurysmal rupture, is extremely low. We report the case of an elderly woman who was mistakenly diagnosed with procedure-related bleeding after gastroscopy. A 0.3 cm polyp was identified and removed during the procedure. The patient later developed shock due to which gastroscopy was repeated; however, no unusual findings were observed. Therefore, abdominopelvic computerized tomography was performed and gastroepiploic artery rupture was detected. Transcatheter arterial embolization was immediately performed without laparotomy, without any complications. The bleeding was controlled, and the patient was discharged after embolization. It is important to acknowledge the possibility of spontaneous rupture of the visceral arteries in elderly individuals with hypertension or atherosclerosis, especially in the event of sudden abdominal pain or shock immediately after an endoscopic procedure. This is the first case report of idiopathic spontaneous rupture of the right gastroepiploic artery successfully managed by transcatheter arterial embolization in South Korea.
cataract surgical problem (2001)

Journal of Cataract & Refractive Surgery: February 2001 - Volume 27 - Issue 2 - p 183-184 doi: 10.1016/S0886-3350(00)00872-5
The Effect of Three‐Tier Formulary Adoption on Medication Continuation and Spending among Elderly Retirees (2007)

Moderate cost sharing increases from three-tier formulary adoption had little effect on medication continuation among elderly enrolled in retiree health plans with relatively generous drug coverage.
CUNI-KIT System for Simultaneous Speech Translation Task at IWSLT 2022 (2022)

Peter Polák, Ngoc-Quan Pham, Tuan Nam Nguyen, Danni Liu, Carlos Mullov, Jan Niehues, Ondřej Bojar, Alexander Waibel. Proceedings of the 19th International Conference on Spoken Language Translation (IWSLT 2022). 2022.
Comprehensive Organometallic Chemistry. The Synthesis, Reactions, and Structures of Organometallic Compounds (1984)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTComprehensive Organometallic Chemistry. The Synthesis, Reactions, and Structures of Organometallic CompoundsDietmar SeyferthCite this: Organometallics 1984, 3, 7, 1135–1136Publication Date (Print):July 1, 1984Publication History Published online7 January 2004Published inissue 1 July 1984https://pubs.acs.org/doi/10.1021/om00085a901https://doi.org/10.1021/om00085a901research-articleACS PublicationsRequest reuse permissionsArticle Views256Altmetric-Citations1LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Efficient Phosphonium-Mediated Synthesis of 2-Amino-1,3,4-oxadiazoles (2008)

We present an efficient, room temperature procedure for the preparation of 2-amino-1,3,4-oxadiazoles. Oxadiazol-2-ones can be activated for SNAr substitution using phosphonium reagents (e.g., BOP). This approach provides convenient access to N,N-disubstituted 2-amino-1,3,4-oxadiazoles, which are difficult to prepare using existing synthetic strategies.
A router based unequal error control scheme for video over the Internet (2003)

This paper presents a router based unequal error protection scheme for video over the Internet. The proposed scheme classifies the whole bitstream into two priorities according to their importance and packetizes them into packets with two priorities. To reduce the loss ratio of video packets with higher priority, an active queue management scheme is designed at each router to provide more chance for these packets to transmit over the Internet. Compared to an end-to-end based approach, in which some redundancy packets are generated to protect the packets with higher priority, our proposed scheme utilizes the whole bandwidth for the source coding. Therefore, the final picture quality is improved.
Anisotropic metamaterial blueprints for cladding control of waveguide modes (2010)

We explore the duality between metric and material properties in the Maxwell’s equations to design metamaterial blueprints for cladding control of waveguide modes. We illustrate designs for circular and rectangular waveguides. In contrast to standard material loading of waveguides, the proposed cladding does not produce hybrid modes. The cutoff frequencies of the propagating modes can be controlled by the material parameters in a simple fashion.
Peptide transport by the multidrug resistance protein MRP1. (2001)

Small hydrophobic peptides were studied as possible substrates of the multidrug resistance protein (MRP)-1 (ABCC1) transmembrane transporter molecule. As observed earlier for P-glycoprotein- (Pgp; ABCB1) overexpressing cells, MRP1-overexpressing cells, including cells stably transfected with the MRP1 cDNA, showed distinct resistance to the cytotoxic peptide N-acetyl-Leu-Leu-norleucinal (ALLN). Resistance to this peptide and another toxic peptide derivative, which is based on a Thr-His-Thr-Nle-Glu-Gly backbone conjugated to butyl and benzyl groups (4A6), could be reversed by MRP1 inhibitors. The reduced toxicity of 4A6 in MRP1-overexpressing cells was found to be associated with lower accumulation of a fluorescein-labeled derivative of this peptide. Glutathione (GSH) depletion had a clear effect on resistance to ALLN but hardly affected 4A6 resistance. In a limited structure-activity study using peptides that are analogous to 4A6, MRP1-overexpressing cells were found to be resistant to these peptides as well. Remarkably, when selecting A2780 ovarian cancer cells for resistance to ALLN, even in the absence of Pgp blockers, resulting cell lines had up-regulated MRP1, rather than any of the other currently known multidrug resistance transporter molecules including Pgp, MRP2 (ABCC2), MRP3 (ABCC3), MRP5 (ABCCS), and the breast cancer resistance protein ABCG2. ALLN-resistant, MRP1-overexpressing cells were found to be cross-resistant to 4A6 and the classical multidrug resistance drugs doxorubicin, vincristine, and etoposide. This establishes MRP1 as a transporter for small hydrophobic peptides. More extensive structure-activity relationship studies should allow the identification of clinically useful peptide antagonists of MRP1.
Erythromelalgia in a patient with AIDS (2000)

Erythromelalgia is a clinical syndrome characterized by burning pain in the extremities together with erythema and increased skin temperature. Typically, the patients experience relief from cold, and aggravation from warmth. Symptoms are hypothesized to be caused by arteriovenous shunting and reduced nutritive skin capillary perfusion with corresponding tissue hypoxia. Erythromelalgia is most often primary, but may be secondary to a wide variety of diseases. We report erythromelalgia in a patient with acquired immune deficiency syndrome (AIDS). At peak pain intensity he actively cooled hands and feet for more than 12 h/day. Many doctors handling human immunodeficiency virus/AIDS patients are unfamiliar with erythromelalgia, and the condition can easily be overlooked, especially the more common milder cases.
A dual‐purpose angioplasty‐drug infusion catheter for the treatment of intragraft thrombus (1994)

An investigational angioplasty-drug infusion catheter (Transport, CardioVascular Dynamics, Irvine, CA) was used to treat a saphenous vein graft stenosis associated with a thrombus. The catheter was successfully used both to infuse urokinase at the site of angioplasty and to perform effective angioplasty, demonstrating the feasibility and utility of a dual-purpose angioplasty catheter capable of angioplasty and/or local drug infusion with the same catheter.
Switched Video Feedback for Sensor Deployment and Target Tracking in a Surveillance Network (2007)

Network surveillance systems provide extended perception and distributed sensing capability in monitored environments through real time monitoring of the target area and target objects using multiple networked sensors. The development of wireless communication and sensing technology make it possible to deploy networked surveillance systems in various environments. We consider a surveillance network where the sensors are static. The task of tracking targets in a surveillance network is challenging because of the following reasons: (1) the location of the sensors need to be optimally deployed. (2) The view of the sensors need to be optimized so that at a given time the targets are shown with a discernable resolution for feature identification. (3) It is important to devise stable control algorithms for accomplishing the surveillance task. When the target moves, it is important to switch the sensing task between sensors to maintain the visibility of the target with adequate resolution. This paper presents a novel method to deploy static sensors given a target region and a dynamic programming method to optimally switch sensors when the target moves. Finally, simulation results demonstrate the efficacy of the proposed approach for tracking targets over an area.