gebhart/patrepeval huggingface dataset:
1H NMR SPECTRA OF LIGNIN MODEL COMPOUNDS (2009)

1H NMR spectral data for lignin model compounds are of interest in connection with the interpretation of NMRspectra of lignins recorded by 1D (1H NMR) and certain 2D spectroscopic techniques. A database comprising such spectral data is being created. Derivatization influences the peak positions in the 1H NMR spectra of lignin modelsto a large extent. Similarly, an exchange of solvent oftenresults in dramatic shifts of peak positions. Solvent andderivatization effects can be employed for theinterpretation of lignin spectra in structural terms.Stereochemistry strongly influences the position of signalsin 1H NMR spectra. This offers a possibility to elucidatethe stereochemistry of the structural elements in ligninsbased on 1H NMR spectral data of model compounds.
Quality-of-Life Outcomes After Transcatheter Aortic Valve Replacement in an Unselected Population (2017)

In a national, contemporary clinical practice cohort of unselected patients, improvement in health status after TAVR was similar to that seen in the pivotal clinical trials. Although the health status results were favorable for most patients, approximately 1 in 3 still had a poor outcome 1 year after TAVR. Continued efforts are needed to improve patient selection and procedural/postprocedural care to maximize health status outcomes of this evolving therapy.
Restoration of fine azimuthal sampling of measured TOF projection data (2010)

TOF acquisition results in additional data dimensions that significantly increase data size. Due to the redundancy of TOF information, data can be compressed almost without loss of resolution. Such compression may consist of azimuthal mashing by a hardware rebinner. In addition to this, some azimuthal and radial information might not be acquired at all due to scanner design. Gaps that exist between the detector blocks are one example of this. TOF iterative and some TOF analytical reconstruction can handle significantly azimuthally undersampled data. Nevertheless, widely used analytical non-TOF reconstruction algorithms, such as FORE+FBP, need fine azimuthal sampling of projection data, as well as TOF FORE. We propose to restore fine azimuthal sampling of measured data for scanner performance assessments exploiting TOF consistency conditions. A practical application is a preprocessing of data for standard scanner characteristics assessment. Point source resolution estimation by analytical non-TOF methods is considered in this paper.
BAFF is a survival and maturation factor for mouse B cells (2002)

Human B cell-activating factor (BAFF) induces mouse surface IgM+ B cells of the immature type from bone marrow and of the immature types 1 and 2 from spleen, as well as of the mature type from spleen to increased longevity in tissue culture. BAFF does so polyclonally and without inducing proliferation in any of these B cell subpopulations. BAFF induces phenotypic and functional maturation of immature to mature B cells so that all immature cells loose C1qRp (AA4.1, 493) expression and type 1 immature cells up-regulate IgD, CD21 and CD23. Immature B cells of types 1 and 2, upon pre-incubation with BAFF, change their reactiveness to Ig-specific antibodies so that they no longer enter apoptosis but now proliferate. However, BAFF does not seem to overcome negative selection of developing immature B cells in vitro.
Outcomes associated with the use of microprocessor-controlled prosthetic knees among individuals with unilateral transfemoral limb loss: A systematic review (2013)

Microprocessor-controlled prosthetic knees (MPKs) have been developed as an alternative to non-microprocessor-controlled knees (NMPKs) to address challenges facing individuals with lower-limb loss. A body of scientific literature comparing MPKs and NMPKs exists but has yet to be critically appraised. Therefore, we conducted a systematic review to examine outcomes associated with the use of these interventions among individuals with transfemoral limb loss. A search of biomedical databases identified 241 publications, of which 27 met the inclusion and exclusion criteria and were reviewed for methodological quality and content. We developed 28 empirical evidence statements (EESs) in 9 outcome categories (metabolic energy expenditure, activity, cognitive demand, gait mechanics, environmental obstacle negotiation, safety, preference and satisfaction, economics, and health and quality of life) based on findings in the literature. The level of evidence supporting these EESs varied due to quantity, quality, and consistency of the results. EESs supported by a moderate level of evidence that noted significant differences between MPKs and NMPKs were derived in five of the nine outcome categories. The results from this review suggest that evidence exists to inform clinical practice and that additional research is needed to confirm existing evidence and better understand outcomes associated with the use of NMPKs and MPKs.
Daily Feed Intake, Energy Intake, Growth Rate and Measures of Dietary Energy Efficiency of Pigs from Four Sire Lines Fed Diets with High or Low Metabolizable and Net Energy Concentrations (2012)

i) evaluate the BW growth, energy intakes and energetic efficiency of pigs fed high and low density diets from 27 to 141 kg BW, ii) evaluate sire line and sex differences when fed both diets, and iii) to compare ME to NE as predictor of pig performance. The experiment had a replicated factorial arrangement of treatments including four sire lines, two sexes (2,192 barrows and 2,280 gilts), two dietary energy densities and a light or heavy target BW, 118 and 131.5 kg in replicates 1 to 6 and 127 and 140.6 kg in replicates 7 to 10. Pigs were allocated to a series of low energy (LE, 3.27 Mcal ME/kg) corn-soybean meal based diets with 16% wheat midds or high energy diets (HE, 3.53 to 3.55 Mcal ME/kg) with 4.5 to 4.95% choice white grease. All diets contained 6% DDGS. The HE and LE diets of each of the four phases were formulated to have equal lysine:Mcal ME ratios. Pigs were weighed and pen feed intake (11 or 12 pigs/pen) recorded at 28-d intervals. The barrow and gilt daily feed (DFI), ME (MEI) and NE (NEI) intake data were fitted to a Bridges function of BW. The BW data of each sex were fitted to a generalized Michaelis-Menten function of days of age. ME and NE required for maintenance (Mcal/d) were predicted using functions of BW (0.255 and 0.179 BW^0.60 respectively). Pigs fed LE diets had decreased ADG (915 vs. 945 g/d, p<0.001) than pigs fed HE diets. Overall, DFI was greater (p<0.001) for pigs fed the LE diets (2.62 vs. 2.45 kg/d). However, no diet differences were observed for MEI (8.76 vs. 8.78 Mcal/d, p = 0.49) or NEI (6.39 vs. 6.44 Mcal/d, p = 0.13), thereby indicating that the pigs compensated for the decreased energy content of the diet. Overall ADG:DFI (0.362 vs. 0.377) and ADG:Mcal MEI (0.109 vs. 0.113) was less (p<0.001) for pigs fed LE compared to HE diets. Pigs fed HE diets had 3.6% greater ADG:Mcal MEI above maintenance and only 1.3% greater ADG:Mcal NEI (0.152 versus 0.150), therefore NEI is a more accurate predictor of growth and G:F than MEI. Pigs fed HE diets had 3.4% greater ADG:Mcal MEI and 0.11% greater ADG:NEI above maintenance than pigs fed LE diets, again demonstrating that NEI is a better predictor of pig performance than MEI. Pigs fed LE diets had similar daily NEI and MEI but grew slower and less efficiently on both ME and NE basis than pigs fed HE diets. The data suggest that the midds NE value (2.132 Mcal/kg) was too high for this source or that maintenance was increased for pigs fed LE diets.
Radiation characteristics of large-area photomixer used for generation of continuous-wave terahertz radiation (2012)

Generation of 2 μW continuous-wave (CW)-terahertz (THz) radiation at 1.2 THz using a large-area photomixer with interdigitated electrodes is reported. The structure of the utilized photomixer allows for unidirectional carrier acceleration over the illuminated areas. We determine the characteristics of the generated CW-THz beam and show that the divergence of this beam is dependent on the spot size of the pump beams focused on the large-area photomixer. An illuminated area with dimensions much larger than the THz wavelength helps to eliminate the focusing optics for the THz beam. Additionally, we demonstrate that the THz beam radiated from the large-area photomixer is steerable by changing the incidence angles of the CW laser beams, as a result of which the phase distribution of the photocurrent along the contact stripes varies. In our experimental setup, the generated THz beam is steerable in the range of −30 to +30 degrees.
Serious photocontact dermatitis induced by topical ketoprofen depends on the formulation (2014)

Photosensitisation to ketoprofen can be mitigated by a patch formulation, which protects the drug from direct UV exposure during skin application, and reduces the formation of even more photoallergic photodegradation products.
PRIDE Statement on the Need for a Moratorium on the CMS Plan to Cite Hospitals for Performing Point-of-Care Capillary Blood Glucose Monitoring on Critically Ill Patients (2015)

Although the CMS is attempting to protect patients with abnormal glycemic control from harm due to inaccurate POC fingerstick capillary BGM testing, their plan will result in more harm than good. A moratorium on enforcement of the prohibition of off-label use of POC capillary BGM testing is needed.
In Vitro Tissue Engineering to Generate a Human‐Sized Auricle and Nasal Tip (2003)

An adult human-sized auricle and nasal tip cartilaginous structure can be grown entirely in vitro using principles of tissue engineering.
Speaker Anonymization Using X-vector and Neural Waveform Models (2019)

The social media revolution has produced a plethora of web services to which users can easily upload and share multimedia documents. Despite the popularity and convenience of such services, the sharing of such inherently personal data, including speech data, raises obvious security and privacy concerns. In particular, a user's speech data may be acquired and used with speech synthesis systems to produce high-quality speech utterances which reflect the same user's speaker identity. These utterances may then be used to attack speaker verification systems. One solution to mitigate these concerns involves the concealing of speaker identities before the sharing of speech data. For this purpose, we present a new approach to speaker anonymization. The idea is to extract linguistic and speaker identity features from an utterance and then to use these with neural acoustic and waveform models to synthesize anonymized speech. The original speaker identity, in the form of timbre, is suppressed and replaced with that of an anonymous pseudo identity. The approach exploits state-of-the-art x-vector speaker representations. These are used to derive anonymized pseudo speaker identities through the combination of multiple, random speaker x-vectors. Experimental results show that the proposed approach is effective in concealing speaker identities. It increases the equal error rate of a speaker verification system while maintaining high quality, anonymized speech.
Development of Color Co-occurrence Matrix Based Machine Vision Algorithms for Wild Blueberry Fields (2012)

Co-occurrence matrix-based textural features were analyzed and three algorithms were developed to identify bare spots, wild blueberry plants, and weeds with the aim of applying agrochemicals to wild blueberry cropping fields in a spot-specific manner. Images were acquired using four cameras and a ruggedized laptop with custom-written programs coded in Microsoft Visual C++. Textural features were extracted from the images using MATLAB and analyzed with SAS. Forty-four textural features were extracted from co-occurrence matrices of NTSC luminance (L), hue, saturation, and intensity (HSI) images. Multiple discriminant analysis using all 44 features (DF_ALL model) showed 98.1% of overall classification accuracy and 83 ms of processing time of an image with C++ calculation. Based on the results of multiple discriminant analysis and two-step linear discrimination plotting, the DF_HSISD, DF_SISD, and HSILD algorithms are preferred algorithms with overall accuracy of 94.9%, 92.7%, and 91.4%, and processing time of 55, 27, and 29 ms, respectively. Any of three reduced textural feature algorithms can be employed for spot-specific application of agrochemicals in wild blueberry cropping fields. The choice of one algorithm over another will depend on whether processing speed or accuracy is more important for the end-users application.
Supplemental Figure Legend from IFNγ Induces DNA Methylation–Silenced GPR109A Expression via pSTAT1/p300 and H3K18 Acetylation in Colon Cancer (2023)

&lt;p&gt;Supplemental Data&lt;/p&gt;
Efficiency and Thermal Stability Enhancements of Sr<sub>2</sub>SiO<sub>4</sub>:Eu<sup>2+</sup>Phosphor via Bi<sup>3+</sup>Codoping for Solid-State White Lighting (2012)

Bi and Eu-codoped yellow-emitting phosphors of composition Sr1.95-xEu0.05BixSiO4 were prepared, and their emission and thermal quenching characteristics were investigated. The initial PL intensity and thermal quenching behaviors of Sr1.95-xEu0.05BixSiO4 were affected by the Bi-codoping as a coactivator. When 0.01 mol % of Bi was codoped to Sr1.95-xEu0.05BixSiO4, it showed an intense emission peak at 543 nm under 450 nm excitation. The peak intensity corresponds to a relative intensity of 112% of a commercial Sr2SiO4:Eu2+ phosphor (Force4 Corp.), which may be attributed to energy transfer between Bi3+ and Eu2+. The results suggest that phosphors deriving from Sr1.95-xEu0.05BixSiO4 will be a breakthrough for white light emitting diode (LEDs) and related applications in terms of efficiency enhancement and thermal stability.
High-resolution He-scattering apparatus for gas–surface interaction studies (1986)

A high-resolution apparatus designed for the study of elastic and inelastic scattering of thermal helium atoms from crystal surfaces is presented. The highly expanded He nozzle beam has an energy spread ΔE/E of about 1.4% and is collimated to 0.2°. The angle subtended by the detector opening as seen from the sample is also 0.2°. Beam intensities as low as 10−6 of the specular beam intensity from a low-temperature clean Pt(111) surface are detectable. Pseudorandom chopping with a resolution of 2.5 μs (flight path 790 mm) is used for time-of-flight (TOF) analysis of the scattered helium. The base pressure in the sample chamber is in the low 10−11 mbar. The capabilities of the apparatus are demonstrated for physisorbed Xe adlayers on Pt(111). The results presented are obtained by using He scattering in various modes: coherent inelastic, coherent elastic, and incoherent (diffuse) elastic. This technique allows for a nondestructive nearly exhaustive characterization of the thermodynamics, structure, and dynamics of physisorbed adlayers on arbitrary substrates.
Origin of Analyte-Induced Porous Silicon Photoluminescence Quenching (2017)

We report on gaseous analyte-induced photoluminescence (PL) quenching of porous silicon, as-prepared (ap-pSi) and oxidized (ox-pSi). By using steady-state and emission wavelength-dependent time-resolved intensity luminescence measurements in concert with a global analysis scheme, we find that the analyte-induced quenching is best described by a three-component static quenching model. In the model, there are blue, green, and red emitters (associated with the nanocrystallite core and surface trap states) that each exhibit unique analyte-emitter association constants and these association constants are a consequence of differences in the pSi surface chemistries.
유아교사가 경험한 언어폭력에 관한 연구 (2018)

연구목적: 유아교사로 생활하는 중 겪게 되는 언어폭력 경험과 상처, 교사들의 대처 자세와 노력 등에 대한 이야기를 들어봄으로써 유아교사의 언어폭력경험을 구체적으로 연구하여 사회적으로 공유하고 제도적 보호 등을 포함하여 대처 방안을 마련하고자 하는데 목적이 있다. 방법: 언어폭력을 경험한 적이 있는 유아교사 8명을 대상으로 면담연구를 실시하였다. 수집된 자료들은 코딩 작업을 통해 범주화하였고, 주제를 도출하고 의미를 해석하여 기술하였다. 결과: 유아교사들은 주로 부모, 원장, 동료교사, 기관 관계자에 의해 언어폭력을 경험하였고 심리적인 상처는 교사직에 대한 회의감, 부담감, 사직의도에도 영향을 미쳤으며 교사들의 소극적 대처는 교사자신을 권력의 약자로 인식하고 있었지만 교사들은 상처를 빨리 잊고 상황을 벗어나기 위한 노력을 하고 있었다. 결론: 유아교사는 ‘서비스업’이라는 사회적 인식이 가하는 폭력으로 인해 직업적 목소리를 낼 수 없는 사회분위기가 있었다. 이를 통해 유아교사에 대한 언어폭력을 줄이기 위한 제도적 지원이 필요함을 시사하였다는 점에서 의의가 있다.
Measuring Very Small Soil Fluxes of N2O &amp; CH4 using a New OF-CEAS Technology (2021)

Earth and Space Science Open Archive PosterOpen AccessYou are viewing the latest version by default [v1]Measuring Very Small Soil Fluxes of N2O & CH4 using a New OF-CEAS TechnologyAuthorsGeorgeBurbaiDIsraelBegashawGrahamLeggettiDKristenMinishLiukangXuSee all authors George BurbaiDCorresponding Author• Submitting AuthorLI-COR BiosciencesiDhttps://orcid.org/0000-0003-2095-0057view email addressThe email was not providedcopy email addressIsrael BegashawLI-COR Biosciencesview email addressThe email was not providedcopy email addressGraham LeggettiDLI-COR BiosciencesiDhttps://orcid.org/0000-0002-2902-698Xview email addressThe email was not providedcopy email addressKristen MinishLI-COR Biosciencesview email addressThe email was not providedcopy email addressLiukang XuLI-COR Biosciencesview email addressThe email was not providedcopy email address
Fabrication of a Stable and Efficient Antibacterial Nanocoating of Zn‐CuO on Contact Lenses (2016)

Abstract The problem of bacterial infections in general, and in medical devices in particular, has led to extensive research to produce antibacterial coatings. The current research presents a unique technique for imparting antibacterial properties to contact lenses. The coating consists of nanoparticles of zinc‐doped copper oxide. In the coating process, active nanoparticles are formed and immediately deposited onto the surface of the contact lens. The coating thus formed is homogeneous and stable, without leaching of the nanoparticles. The antibacterial activity was evaluated against Gram‐positive and Gram‐negative bacteria. The optimization of the coating process has led to a smaller particle size and good antibacterial activity.
Abstract 3026: Targeting aberrantly activated AREG-EGFR signaling in CRTC1-MAML2-positive mucoepidermoid carcinoma. (2013)

Abstract Salivary gland tumors (SGT) are a group of highly heterogeneous head and neck malignancies with widely varied clinical outcomes and no standard effective treatments. The CRTC1-MAML2 gene fusion, encoded by a recurring chromosomal translocation t(11;19)(q14-21;p12-13), is a highly specific genetic alteration in more than 50% of mucoepidermoid carcinoma (MEC), the most common malignant SGT. In this study, we aimed to define the role of the CRTC1-MAML2 oncogene in the maintenance of MEC tumor growth and to investigate critical downstream target genes and pathways for therapeutic targeting of MEC. By performing gene expression analyses and functional studies via RNA interference and pharmacological modulation, we determined the importance of the CRTC1-MAML2 fusion gene and its downstream AREG-EGFR signaling in human MEC cancer cell growth ad survival in vitro and in vivo using human MEC xenograft models. We found that CRTC1-MAML2 fusion oncogene was required for the growth and survival of fusion-positive human MEC cancer cells in vitro and the in vivo. CRTC1-MAML2 induced the up-regulation of the EGFR ligand AREG by co-activating the transcription factor CREB and AREG subsequently activated EGFR signaling in an autocrine manner that promoted MEC cell growth and survival. Importantly, CRTC1-MAML2-positive MEC cells were highly sensitive to EGFR signaling inhibition. Therefore, our study revealed that aberrantly activated AREG-EGFR signaling is required for CRTC1-MAML2-positive MEC cell growth and survival, suggesting that EGFR-targeted therapies will benefit patients with unresectable CRTC1-MAML2-positive MEC. Citation Format: Zirong Chen, Yumei Gu, Chengbin Hu, Jian-Liang Li, Shuibin Lin, Huangxuan Shen, Chunxia Cao, Jie Chen, Jiancheng Li, Patick K. Ha, Federic J. Kaye, James D. Griffin, Lizi Wu. Targeting aberrantly activated AREG-EGFR signaling in CRTC1-MAML2-positive mucoepidermoid carcinoma. [abstract]. In: Proceedings of the 104th Annual Meeting of the American Association for Cancer Research; 2013 Apr 6-10; Washington, DC. Philadelphia (PA): AACR; Cancer Res 2013;73(8 Suppl):Abstract nr 3026. doi:10.1158/1538-7445.AM2013-3026
ChemInform Abstract: New Orthocyclophane Cyclotetraphosphazanes: (C6H4N2(PR)2)2 (R: Ph, Me) (III) and (C6H4N2(PPh)(PhPS))2 (1991)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Дилемма безопасности в рамках международного курса на ядерное разоружение: анализ и перспективы (2013)

Мазур Е. А. Дилемма безопасности в рамках международного курса на ядерное разоружение: анализ и перспективы / Е. А. Мазур // Міжнародні читання з міжнародного права пам’яті професора П. Є. Казанського : матеріали четвертої міжнар. наук. конф. (м. Одеса, 8–9 лист. 2013 р.) / відп. за випуск к.ю.н., доц. М. І. Пашковський; Національний університет Одеська юридична академія. – Одеса : Фенікс, 2013. – С. 547-550.
Soluble receptor for advanced glycation end products (sRAGE) and endogenous secretory RAGE (esRAGE) in amniotic fluid: modulation by infection and inflammation (2008)

Intra-amniotic infection/inflammation is associated with increased amniotic fluid concentrations of sRAGE and esRAGE. Changes in the amniotic fluid concentration of sRAGE and esRAGE may represent part of the immune response to intra-amniotic infection/inflammation.
X chromosome gene dosage as a determinant of congenital malformations and of age-related comorbidity risk in patients with Turner syndrome, from childhood to early adulthood (2019)

Objective Turner Syndrome is associated with several phenotypic conditions associated with a higher risk of subsequent comorbidity. We aimed to evaluate the prevalence of congenital malformations and the occurrence of age-related comorbid conditions and to determine whether the frequencies of congenital and acquired conditions depend on X chromosome gene dosage, as a function of karyotype subgroup. Design and methods This national retrospective observational cohort study includes 1501 patients. We evaluated the prevalence of congenital malformations and the cumulative incidence of subsequent specific comorbidities at five-year intervals, from the ages of 10 to 30 years, with stratification by karyotype subgroup: 45,X (n = 549), 45,X/46,isoXq (n = 280), 46,X,r(X)/46,XX (n = 106), 45,X/46,XX (n = 221), presence of Y (n = 87). Results Median age was 9.4 (3.7-13.7) years at first evaluation and 16.8 (11.2-21.4) years at last evaluation. Congenital heart (18.9%) malformations were more frequent in 45,X patients, and congenital renal (17.2%) malformations were more frequent in 45,X, 45,X/46,isoXq and 46,X,r(X)/46,XX patients than in those with 45,X/46,XX mosaicism or a Y chromosome (P < 0.0001). The cumulative incidence of subsequent acquired conditions, such as thyroid disease, hearing loss, overweight/obesity, dyslipidemia and, to a lesser extent, celiac disease, glucose intolerance/type 2 diabetes, hypertension and liver dysfunction increased with age, but less markedly for patients with mosaicism than for those with other karyotypes. Patients with a ring chromosome were more prone to metabolic disorders. Conclusion These data suggest that X gene chromosome dosage, particularly for Xp genes, contributes to the risk of developing comorbidities.