gebhart/patrepeval huggingface dataset:
Reactions of coordinated molecules. 31. Rhena .beta.-keto imine derivatives of several biologically important molecules containing 2-ethylamino groups (1982)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTReactions of coordinated molecules. 31. Rhena .beta.-keto imine derivatives of several biologically important molecules containing 2-ethylamino groupsC. M. Lukehart and M. RajaCite this: Inorg. Chem. 1982, 21, 3, 1278–1280Publication Date (Print):March 1, 1982Publication History Published online1 May 2002Published inissue 1 March 1982https://pubs.acs.org/doi/10.1021/ic00133a086https://doi.org/10.1021/ic00133a086research-articleACS PublicationsRequest reuse permissionsArticle Views57Altmetric-Citations11LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Reducing multipath tracking errors in spread-spectrum ranging systems (1992)

Analysis of coherent and noncoherent delay lock loops shows that a smaller early-late spacing than the commonly used one chip time reduces multipath tracking errors considerably. The results are especially interesting for spreadspectrum ranging systems such as GPS.
Mesoblastic Nephroma of Adulthood Report of Three Cases (1993)

Mesoblastic nephroma is an uncommon congenital tumor of infancy that rarely occurs in adults. We report three patients (two were female, one was male) who had mesoblastic nephroma of adulthood and who presented at 45, 64, and 66 years of age with hematuria, flank mass, and pain. All underwent nephrectomy without postoperative adjuvant therapy. The tumors were solitary yellow-tan masses with solid and cystic areas involving the renal cortex (three cases) with extension into the renal pelvis and calyces (two) and ureter (one). Microscopically, all consisted of uniform spindle cell proliferations with entrapped dilated renal tubules. Focal necrosis was present in two, but no atypia or mitoses were identified in any case. The spindle cells displayed cytoplasmic immunoreactivity for vimentin, desmin, panmuscle actin (HHF-35), and alpha-smooth-muscle actin, but were nonreactive for keratin (AE1/AE3), epithelial membrane antigen, and S-100 protein. Electron microscopy revealed the presence of smooth-muscle differentiation in two cases and undifferentiated mesenchyme in one. All tumors were DNA diploid by flow cytometry. The patients were free of recurrence 8 months-2 years postoperatively. Because surgical excision may be curative, mesoblastic nephroma in adult patients must be differentiated from spindle cell neoplasms of the kidney that require additional therapy.
Experimental demonstration of the DPTS QKD protocol over a 170 km fiber link (2019)

Quantum key distribution (QKD) is a promising technology that aims to solve the security problem arising from the advent of quantum computers. While the main theoretical aspects are well developed today, limited performances, in terms of the achievable link distance and the secret key rate, are preventing the deployment of this technology on a large scale. More recent QKD protocols, which use multiple degrees of freedom for encoding of the quantum states, allow enhancement of the system performances. Here, we present the experimental demonstration of the differential phase-time shifting protocol up to 170 km of the fiber link. We compare its performance with the well-known coherent one-way and differential phase shifting protocols, demonstrating a higher secret key rate up to 100 km. Moreover, we propagate a classical signal in the same fiber, proving the compatibility of quantum and classical light.
Blocklike Fluorocarbon and Hydrocarbon Copolymer Films via Surface-Initiated ATRP and Postpolymerization Reactions (2005)

We report a new method to prepare ultrathin blocklike copolymer films on metal surfaces with molecularly optimized surface and barrier properties. Copolymer films containing various fluorocarbon and/or hydrocarbon side chains were created by a one-step surface-initiated polymerization of poly(hydroxyethyl methacrylate) (PHEMA) followed by straightforward derivatization steps. Exposure of PHEMA to perfluorobenzoyl chloride results in a perfluoroaryl-modified PHEMA film that exhibits high conversion and outstanding barrier properties but does not present an oleophobic surface. We have previously demonstrated that fluorinated esters created in this manner may be hydrolyzed back to PHEMA by brief exposure to base. Controlled hydrolysis results in regeneration of PHEMA in the outer surface region that can be subsequently rederivatized with alkyl or fluoroalkyl acid chlorides to create copolymer films with tailored surface composition. Surface properties are solely affected by the species used during rederivatization while barrier properties result from the combined conversion, structuring, and surface properties of the copolymer film.
Tidal signals in basin-scale acoustic transmissions (1993)

Travel times of acoustic signals were measured between a bottom-mounted source near Oahu and five bottom-mounted receivers located near Washington, Oregon, and California in 1988 and 1989. This paper discusses the observed tidal signals. At three out of five receivers, observed travel times at M2 and S2 periods agree with predictions from a barotropic tide model to within ±30° in phase and a factor of 1.6 in amplitude. The discrepancies at the fourth and fifth receivers can largely be accounted for with a simple model for the generation of baroclinic tides by interactions between the barotropic tides and guyots in the Moonless mountains. These baroclinic tides are phase locked to the astronomical tide-generating forces. A simple model is used to estimate the conversion of energy from barotropic to baroclinic tides by the world’s seamounts. At M2, the conversion amounts to about 1×1018 erg s−1, or about 4% of the total dissipation at M2. Although this estimate is very approximate, it is similar to other published values.
Intensity of Statin Treatment in Korean Patients with Acute Myocardial Infarction and Very Low LDL Cholesterol (2019)

More intensive statin therapy was associated with significantly lower major adverse cardiovascular events in patients with acute MI and very low LDL cholesterol compared with less intensive statin therapy.
Discriminative Semi-Markov Models for automated mitotic phase labelling (2012)

With the widespread use of time-lapse data to understand cellular function, there is a need for tools which facilitate high-throughput analysis of data. We present a system for automated segmentation and mitotic phase labelling based on a wide margin discriminative Semi-Markov Model. This work takes the novel approach of using temporal features evaluated over the whole of the mitotic phases rather than over single frames, thereby capturing the distinctive behaviour over the phases. This approach extends and substantially improves on our previous approach of using dynamic time warping to align temporal feature signals to a reference.
Al/sub x/O/sub y/ induced intermixing in GaAs/AlGaAs quantum wells (2003)

Quantum well interdiffusion has been widely studied in recent years due to potential applications in optoelectronics. The main advantages with the quantum well intermixing technique is the ability to selectively intermix parts of an already grown wafer to shift the excitonic energy. This can be used to integrate active and passive quantum devices without the need for regrowth or patterned growth. Commonly Impurity-Free interdiffusion (IFID) is mostly used for fabrication of active devices, due to the low defect density present after processing, and the lower degradation of the material, this is usually achieved by deposition of a dielectric on the surface of the wafer. Very recently, it was observed that IFID can be achieved by using laterally oxidized AlAs layers. These layers are commonly used for current confinement apertures in VCSELs and Edge emitters. In this paper we present results which show a systematic study of the effect of Al/sub x/O/sub y/ induced interdiffusion.
Inverse Airfoil Design Method for Generating Varieties of Smooth Airfoils Using Conditional WGAN-GP (2021)

Abstract Machine learning models are recently utilized for airfoil shape generation methods. It is desired to obtain airfoil shapes that satisfies required lift coefficient. Generative adversarial networks (GAN) output reasonable airfoil shapes. However, shapes obtained from ordinal GAN models are not smooth, and they need smoothing before flow analysis. Therefore, the models need to be coupled with B'ezier curves or other smoothing methods to obtain smooth shapes. Generating shapes without any smoothing methods is challenging. In this study, we employed conditional Wasserstein GAN with gradient penalty (CWGAN-GP) to generate airfoil shapes, and the obtained shapes are as smooth as those obtained using smoothing methods. With the proposed method, no additional smoothing method is needed to generate airfoils. Moreover, the proposed model outputs shapes that satisfy the lift coefficient requirements.
A Multistep Detection Scheme Based on Iteration for Cooperative Spectrum Sensing in Cognitive Radio (2011)

In cognitive radio (CR) networks, two main challenges faced by cooperative spectrum sensing are low detection performance and long detection time in low SNR scenario. To the best of our knowledge, little study analyzes these two problems simultaneously and thoroughly. Therefore, this paper proposes a novel spectrum sensing scheme, termed multistep detection (MD) scheme, which aims to resolve the above two problems. For MD scheme which consists of five steps, we focus on the following two key parts: two-threshold detection and iteration detection. For the two-threshold detection, we make theoretical analysis about the establishment of the two thresholds. And for the iteration detection, a novel spectrum sensing algorithm is proposed to improve the detection performance in low SNR. The iteration algorithm utilizes the following property to improve the signal's SNR: the variance of the mean of independent and identity Gaussian random variables is 1/K of one variable's variance. The simulation results indicate that the proposed MD scheme outperforms the traditional cooperative scheme both on the detection performance and the detection time significantly.
Higher cyclobutane pyrimidine dimer and (6‐4) photoproduct yields in epidermis of normal humans with increased sensitivity to ultraviolet B radiation (1996)

Cyclobutane pyrimidine dimer (CPD) and (6-4) photoproduct induced in the epidermis of five Japanese volunteers exposed to ultraviolet (UVB) radiation were measured with monoclonal antibodies specific for each photoproduct. The volunteers comprised two individuals who are sensitive to solar irradiation (low minimal erythema dose [MED]) and three who are less sensitive. The yields of CPD and (6-4) photoproduct were within similar ranges after 1 MED or 3 MED doses. The yields of both photoproducts after the same dose of irradiation (120 mJ/cm2) were higher in UV-sensitive individuals than in less sensitive individuals. By 24 h after irradiation, an average of 60% of CPD had been removed after the 1 MED dose, 27% after the 3 MED dose and 34% after 120 mJ/cm2. The (6-4) photoproduct was removed within 24 h, independently of the dose of UVB tested. These data suggest that DNA photoproducts participate in initiating UVB-induced erythema, and partially explain why individuals with higher sensitivity to UVB have a higher risk of UV-induced skin cancer.
Prostate fiducial marker detection with the use of multi-parametric magnetic resonance imaging (2017)

Background and purposeThe introduction of a magnetic resonance (MR)-only workflow in radiotherapy requires that fiducial markers, used for position verification, can be detected on MR images. Here we evaluate a model for marker detection in prostate cancer patients by combining information from our hospital standard multi-parametric (mp-) MRI protocol (T1-weighted – T1w, T2-weighted – T2w, B0) with dedicated sequences (balanced steady-state free precession sequence – bTFE, susceptibility weighted imaging – SWI).Materials and methodsThirty two patients scheduled for external-beam radiotherapy received a mp-MRI and computed-tomography; the latter was used as ground truth location of the markers. A logistic regression model was implemented for marker detection by combining features from all imaging sequences. The performance of the individual and combined sequences was assessed by determining true and false positive detections.ResultsThe combination of different sequences (mp-MRI) resulted in a better performance than the best imaging sequence alone (bTFE). Combining mp-MRI + bTFE resulted in good accuracy and a true positive detection rate of 0.94.ConclusionsThe standard mp-MRI provides valuable information to detect fiducial markers. The combination of different sequences outperforms the use of a single dedicated sequence. We recommend the addition of a bTFE to the standard mp-MRI protocol to improve fiducial marker detection.
Acrylamide genotoxicity in young versus adult gpt delta male rats (2011)

The recent discovery that the potent carcinogen acrylamide (AA) is present in a variety of fried and baked foods raises health concerns, particularly for children, because AA is relatively high in child-favoured foods such as potato chips and French fries. To compare the susceptibility to AA-induced genotoxicity of young versus adult animals, we treated 3- and 11-week-old male gpt delta transgenic F344 rats with 0, 20, 40 or 80 p.p.m. AA via drinking water for 4 weeks and then examined genotoxicity in the bone marrow, liver and testis. We also analysed the level of N7-(2-carbamoyl-2-hydroxyethyl)-guanine (N7-GA-Gua), the major DNA adduct induced by AA, in the liver, testis and mammary gland. At 40 and 80 p.p.m., both age groups yield similar results in the comet assay in liver; but at 80 p.p.m., the bone marrow micronucleus frequency and the gpt-mutant frequency in testis increased significantly only in the young rats, and N7-GA-Gua adducts in the testis was significantly higher in the young rats. These results imply that young rats are more susceptible than adult rats to AA-induced testicular genotoxicity.
Personal and Workplace Factors and Median Nerve Function in a Pooled Study of 2396 US Workers (2015)

Occupational and nonoccupational factors have adverse effects on median nerve function. Measuring median nerve function eliminates possible reporting bias that may affect symptom-based carpal tunnel syndrome case definitions. These results suggest that previously observed associations between carpal tunnel syndrome and occupational factors are not the result of such reporting bias.
Alcohol Use Disorder Comorbidity in Eating Disorders (2004)

Individuals with eating disorders and AUDs exhibit phenotypic profiles characterized by both anxious, perfectionistic traits and impulsive, dramatic dispositions. These traits mirror the pattern of control and dyscontrol seen in individuals with this comorbid profile and suggest that anxiety modulation may be related to alcohol use in this group.
The crystal structure of the p27 component of human dynactin (2011)

C222 has been performed and will be highlighted during presentation. The crystals just have been shipped to BM-14 beam line at France and results obtained will be elaborated during presentation. The structure studies of BRCA1 (1560-1859) will help in understanding the pathogenicity of mutations which may provide very important information for predisposing someone at the high risk of cancer.
Prediction of postoperative analgesic requirements by facial electromyography during simultaneous BIS monitoring (2001)

s and Programme: European Society of Anaesthesiologists; 9th Annual Meeting with the Swedish Society of Anaesthesiology; Gothenburg, Sweden, 7-10 April 2001: Acute and Chronic Pain Management
Metal vapor arc ion plating (1986)

A method and apparatus for ion plating are described. The apparatus uses more negative than a first electrode voltage in a vacuum arc remelt system to attract low energy ions from the anode electrode to the article to be plated. 2 figs.
A study of phase equilibria and heterojunctions in Ga–In–As–Sb quaternary system (1978)

Abstract The phase diagram of the Ga–In–As–Sb quaternary system has been determined experimentally and also has been treated on the base of thermodynamic calculations. The liquidus data were obtained by DTA and solidus data were determined using electron microprobe analysis on LPE‐layers of Ga x In 1– x As y Sb 1– y on GaSb and InAs substrates. Isolattice‐parameter heterostructures prepared on these substrates were free of mismatch dislocations and suitable for application to light‐emitting diodes and semiconductor lasers.
PEEP Generated by High-Flow Nasal Cannula in a Pediatric Model (2019)

HFNCs deliver varying amounts of PEEP at the alveolar level with flows of 6-60 L/min. Increasing flow and decreasing leak resulted in the generation of greater PEEP. PEEP levels differed across cannulas and model weights at the same leak level, likely due to differences in the nasal interface between the HFNC device and the model nares.
Selective retina therapy monitoring by speckle variance optical coherence tomography for dosimetry control (2020)

We found a reliable correlation between the svOCT peak values and the degree of retinal lesion formation, which can be used for selecting proper laser energy during SRT.
Kirana: a solid-state megapixel uCMOS image sensor for ultrahigh speed imaging (2013)

This paper describes a solid-state sensor for ultra-high-speed (UHS) imaging. The 'Kirana' sensor was designed and manufactured in a 180 nm CMOS technology to achieve full-frame 0.7 Megapixel video capture at speeds at 2 MHz. The 30 &mu;m pixels contain a pinned photodiode, a set of 180 low-leakage storage cells, a floating-diffusion, and a source follower output structure. Both the individual cells and the way they are arranged in the pixel are novel. The pixel architecture allows correlated double sampling for low noise operation. In the fast mode, the storage cells are operated as a circular buffer, where 180 consecutive frames are stored until receipt of a trigger; up to 5 video-bursts per second can be read out. In the 'slow' mode, the storage cells act like a pipeline; the sensor can be read out like a conventional sensor at a continuous frame rate of 1,180 fps. The sensor architecture is fully scalable in resolution since memory cells are located inside each pixel. The pixel architecture is scalable in memory depth (number of frames) as a trade-off with pixel size, dependent on application. The present implementation of 0.7 Mpixels has an array focal plane which is optimized for standard 35 mm optics, whilst offering a competitive 180-frame recording depth. The sensor described has been manufactured and is currently being characterized. Operation of the sensor in the fast mode at 2 million frames per second has been achieved. Details on the camera/sensor operation are presented together with first experimental results.
ChemInform Abstract: NEW SYNTHETIC ROUTE TO (.+‐.) LYSERGIC ACID (1981)

Abstract Wittig‐Reaktion des bekannten Aldehyds (I) mit dem Phosphoran (II) liefert den Ester (IIIa), der über die Stufen (IIIb), (IIIc) und (IIId) in das Amin (IIIe) (Isolierung als Toluolsulfonat) übergeführt wird.
Robot navigation in crowds via deep reinforcement learning with modeling of obstacle uni-action (2022)

Mobile robots operating in public environments require the ability to navigate among humans and obstacles in a socially compliant and safe manner. Previous work has shown the power of deep reinforcement learning (DRL) techniques by employing them to train efficient policies for robot navigation. However, most DRL-based robot navigation methods only consider dynamic pedestrians and do not take static obstacles into account. The ability to approach pedestrians and obstacles differently will improve a robot's navigation efficiency. In this work, we propose a novel network, the obstacle-robot uni-action (ORU) network, to encode the one-way direct effects of obstacles on the robot. Obstacles' indirect effects on the robot, represented by the obstacle-human uni-action (OHU), together with human–human interaction (HHI), are concatenated to a human–robot interaction (HRI) network to obtain the features of a crowd's effects on the robot. We also implement a variable reaching goal reward and an approaching goal reward in our model, which can enhance the method's performance in terms of navigation time. Results of test experiments in both simulation and real datasets demonstrate that the proposed method outperforms state-of-the-art methods.
Data from SLC5A8 Triggers Tumor Cell Apoptosis through Pyruvate-Dependent Inhibition of Histone Deacetylases (2023)

&lt;div&gt;Abstract&lt;p&gt;Tumor cells up-regulate glycolysis but convert pyruvate into lactate instead of oxidizing it. Here, we show that pyruvate, but not lactate, is an inhibitor of histone deacetylases (HDAC) and an inducer of apoptosis in tumor cells and that SLC5A8, a Na&lt;sup&gt;+&lt;/sup&gt;/monocarboxylate cotransporter, is obligatory for this process. We found that &lt;i&gt;SLC5A8&lt;/i&gt; is expressed in nontransformed breast epithelial cell lines but silenced by DNA methylation in tumor cell lines. The down-regulation of the gene is also evident in primary breast tumors. When MCF7 breast tumor cells are transfected with SLC5A8 cDNA, the cells undergo pyruvate-dependent apoptosis. Butyrate and propionate also induce apoptosis in SLC5A8-expressing cells, whereas lactate does not. The differential ability of these monocarboxylates to cause apoptosis in SLC5A8-expressing MCF7 cells correlates with their ability to inhibit HDACs. Apoptosis induced by SLC5A8/pyruvate in MCF7 cells is associated with up-regulation of p53, Bax, tumor necrosis factor–related apoptosis-inducing ligand (TRAIL), TRAIL receptor (TRAILR) 1, and TRAILR2 and down-regulation of Bcl2 and survivin. Lactate dehydrogenase isozymes are differentially expressed in nontransformed cells and tumor cells such that the latter convert pyruvate into lactate. Silencing of &lt;i&gt;SLC5A8&lt;/i&gt; coupled with conversion of pyruvate into lactate in tumor cells correlates with increased HDAC activity in these cells compared with nontransformed cells. Our studies thus identify pyruvate as a HDAC inhibitor and indicate that the Na&lt;sup&gt;+&lt;/sup&gt;-coupled pyruvate transport underlies the tumor-suppressive role of SLC5A8. We propose that tumor cells silence &lt;i&gt;SLC5A8&lt;/i&gt; and convert pyruvate into lactate as complementary mechanisms to avoid pyruvate-induced cell death. (Cancer Res 2006; 66(24): 11560-4)&lt;/p&gt;&lt;/div&gt;