gebhart/patrepeval huggingface dataset:
Increased power collection efficiency of conventional silicon photovoltaic modules with holographic light management techniques (2018)

Conventional silicon Photovoltaic (PV) modules often have a significant surface obstruction that reduces the collection of incident solar illumination and energy conversion efficiency. In this paper, light management methods that combine low cost holographic optical elements and diffusers into conventional PV modules are evaluated to capture unused illumination. It is found that by using reflection volume holograms (RVHs) with 300 nm spectral bandwidth in combination with a diffuser on a PV module with 12% of its surface area not covered with active PV cell regions that an improvement in power collection efficiency of 9.36% is possible.
Modélisation de structures de type plaque contenant des matériaux piézoélectriques (2008)

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Photonic Crystals from Emulsion Templates (2001)

Macroporous titania, which undergoes transition to the rutile phase by calcination without collapse of the pore structure, is obtained by polymerizing a titania sol suspended around “colloidal crystals” of oil droplets. The deformable template counteracts cracking of the titania phase. The Figure shows a scanning electron micrograph of a rutile sample with 200 nm pores obtained by the method described.
Inhibitory effect of caffeic acid esters on azoxymethane-induced biochemical changes and aberrant crypt foci formation in rat colon. (1993)

Previous work from this laboratory established that caffeic acid esters, present in the propolis of honey bee hives, are potent inhibitors of human colon tumor cell growth, suggesting that these compounds may possess antitumor activity against colon carcinogenesis. The present study was designed to investigate (a) the inhibitory effects of methyl caffeate (MC) and phenylethyl caffeate (PEC) on azoxymethane (AOM)-induced ornithine decarboxylase (ODC), tyrosine protein kinase (TPK), and arachidonic acid metabolism in liver and colonic mucosa of male F344 rats, (b) the effects of caffeic acid, MC, PEC, phenylethyl-3-methylcaffeate (PEMC), and phenylethyl dimethylcaffeate (PEDMC) on in vitro arachidonic acid metabolism in liver and colonic mucosa, and (c) the effects of PEC, PEMC, and PEDMC on AOM-induced aberrant crypt foci (ACF) formation in the colon of F344 rats. At 5 weeks of age, groups of animals were fed diets containing 600 ppm MC or PEC (biochemical study) or 500 ppm PEC, PEMC, or PEDMC (ACF study). Two weeks later, all animals except the vehicle-treated groups were given s.c. injections of AOM, once weekly for 2 weeks. The animals intended for the biochemical study were sacrificed 5 days later and colonic mucosa and liver were analyzed for ODC, TPK, lipoxygenase, and cyclooxygenase metabolites. The animals intended for the ACF study were sacrificed 9 weeks later and analyzed for ACF in the colon. The results indicate that the PEC diet significantly inhibited AOM-induced ODC (P < 0.05) and TPK (P < 0.001) activities in liver and colon. The PEC diet significantly (P < 0.001) suppressed the AOM-induced lipoxygenase metabolites 8(S)- and 12(S)-hydroxyeicosatetraenoic acid (HETE). The animals fed the MC diet exhibited a moderate inhibitory effect on ODC and 5(S)-, 8(S)-, 12(S)-, and 15(S)-HETEs and a significant (P < 0.001) effect on colonic TPK activity. However, the MC and PEC diets showed no significant inhibitory effects on cyclooxygenase metabolism. In an in vitro study, caffeic acid and MC showed inhibitory effects on HETE formation only at a 100 microM concentration, whereas PEC, PEMC, and PEDMC suppressed in vitro HETE formation in a dose-dependent manner. AOM-induced colonic ACF were significantly inhibited in the animals fed PEC (55%), PEMC (82%), or PEDMC (81%). The results of the present study indicate that PEC, PEMC, and PEDMC, present in honey, inhibit AOM-induced colonic preneoplastic lesions, ODC, TPK, and lipoxygenase activity, which are relevant to colon carcinogenesis.
Thermal energy storage co-benefits in building applications transferred from a renewable energy perspective (2022)

Although one of the main aims of using renewable energy sources in building applications is to reduce the environmental impact caused by the high global energy demand of buildings, it can also produce other positive effects, known as co-benefits. Thermal energy storage technologies are often used in building applications, either integrated into the renewable system or independently, for energy savings or energy efficiency reasons. This paper demonstrates that it is possible to identify the co-benefits of the use of thermal energy storage in buildings by cross-sectorizing the renewable energy and thermal energy storage sectors. To this end, this article first reviews the literature on the co-benefits of renewable energy for building applications, followed by an evaluation on how these co-benefits can be attributed to thermal energy storage in buildings. As a result of a keywords analysis, the main co-benefits of thermal energy storage were identified related to environmental, health, economic, cost, and policies aspects.
Preparation of aryl benzyl ketones by [1,2]-Wittig rearrangement (2002)

-(Benzotriazol-1-yl)benzyl ethers 4a-f were readily prepared by condensation of benzotriazole, aryl aldehydes and benzyl alcohols. A one-pot reaction involving deprotonation of 4 followed by [1,2]-Wittig rearrangement and departure of the benzotriazolyl group resulted in aryl benzyl ketones 6a-f in good yields.
Vibration Damping Enhancement in Hybrid Carbon Fiber Composites With Zinc Oxide Nanowire Interphase (2014)

Traditional composite materials invented to be used in structures with the purpose of high load-bearing with excellent in-plane properties. Continuous fiber reinforced composites are one of the mostly used categories of advanced composites. This class of composites has gained a lot of attention due to their light-weight and decent mechanical properties. However, additional material design is required to tune both mechanical and structural properties of these composites. Since the load transfer between reinforcement phase and polymer matrix happens at the interfacial region, a better interphase might result in a composite with higher vibration damping. In this study, a gradient interphase between carbon fiber and polymer matrix has been created by using ZnO nanowires to engineer the damping loss factor of the carbon fiber composites. For the growth of ZnO nanowires on the carbon fabric, low temperature hydrothermal reaction has been used. Then the carbon fabrics with ZnO nanowires were infiltrated with a low viscosity epoxy using vacuum assisted resin transfer molding technique. The stiffness and structural damping of the composite were examined using dynamic mechanical analysis. The results show that the damping properties of hybrid composites using ZnO nanowires are enhanced compare to the bare carbon fabric composites. Since the growth of ZnO nanowires is a tunable process, the length, diameter and aspect ratio of the nanowires and consequently the architecture of the interphase can be tailored for the desired vibration damping in the system. Thus, the hybrid composites with ZnO nanowire interphase can be used to enhance the energy dissipation in a structural system.
Nanomaterial Categorization for Assessing Risk Potential To Facilitate Regulatory Decision-Making (2015)

For nanotechnology to meet its potential as a game-changing and sustainable technology, it is important to ensure that the engineered nanomaterials and nanoenabled products that gain entry to the marketplace are safe and effective. Tools and methods are needed for regulatory purposes to allow rapid material categorization according to human health and environmental risk potential, so that materials of high concern can be targeted for additional scrutiny, while material categories that pose the least risk can receive expedited review. Using carbon nanotubes as an example, we discuss how data from alternative testing strategies can be used to facilitate engineered nanomaterial categorization according to risk potential and how such an approach could facilitate regulatory decision-making in the future.
LEO of III-nitride on Al 2 O 3 and Si substrates (2000)

Lateral epitaxial overgrowth (LEO) has recently become the method of choice to reduce the density of dislocations in heteroepitaxial GaN thin films, and is thus expected to lead to enhanced performance devices. We present here the LEO growth and characterization of GaN films by low pressure metalorganic chemical vapor deposition. Various substrates were used, including basal plane sapphire and oriented Si substrates. The steps in the LEO growth technology will be briefly reviewed. The characterization results will be discussed in detail. The structural, electrical and optical properties of the films were assessed through scanning, atomic and transmission electron microscopy, x-ray diffraction, capacitance-voltage, deep level transient spectroscopy, photoluminescence, and scanning cathodoluminenscence measurements. Single-step and double- step LEO GaN was achieved on sapphire. Similarly high quality LEO grown GaN films were obtained on sapphire and silicon substrates. Clear and dramatic reduction in the density of defects are observed in LEO grown materials using the various characterization techniques mentioned previously.
Fabrication and Magnetic Properties of Ni Nanospheres Encapsulated in a Fullerene-like Carbon (2005)

A very simple, efficient, and economical synthetic technique, which produces fascinating fullerene-like Ni-C (graphitic) core-shell nanostructures at a relatively low temperature, is reported. The thermal dissociation of Ni acetylacetonate is carried out in a closed vessel cell (Swagelok) that was heated at 700 degrees C for 3 h. The encapsulation of ferromagnetic Ni nanospheres into the onion structured graphitic layers is obtained in a one-stage, single precursor reaction, without a catalyst, that possesses interesting magnetic properties. The magnetoresistance (MR) property of Ni nanospheres encapsulated in a fullerene-like carbon was measured, which shows large negative MR, of the order of 10%. The proposed mechanism for the formation of the Ni-C core-shell system is based on the segregation and the surface flux formed in the Ni and carbon particles during the reaction under autogenic pressure at elevated temperature.
Supplementary Tables 1 - 3, Methods, Figure Legends from c-Abl Modulates Tumor Cell Sensitivity to Antibody-Dependent Cellular Cytotoxicity (2023)

&lt;p&gt;Supplementary Table 1. Gene symbol and target sequences for two pooled siRNAs used in primary screens. Supplementary Table 2. Gene symbols and target sequences for four individual siRNAs utilized in secondary screens. Supplementary Table 3. Gene symbols and QuantiTect Primer Assays (Qiagen) used for quantitative reverse-transcription PCR (Q-RT-PCR) assessments.&lt;/p&gt;
Antisense oligonucleotide nanocapsules efficiently inhibit EWS-Fli1 expression in a Ewing's sarcoma model. (2006)

The cytogenetic abnormality of Ewing's sarcoma is related to the presence of a balanced t(11;22) translocation expressing the EWS-Fli1 chimeric fusion protein. Oligonucleotides (ODNs) are specific compounds that inhibit gene expression at the transcriptional level. They possess a poor bioavailability and are degraded by nucleases very rapidly. Therefore, there is a strong need for the development of ODN drug delivery systems. In the present study, polyisobutylcyanoacrylate nanocapsules entrapping ODNs in their aqueous core were prepared, with high encapsulation yield (99%). Previous studies have demonstrated that such complexes were able to inhibit tumor growth in mice. Nevertheless, no information was available about their mode of action at the cellular level. The aim of this study was to investigate the efficacy of these ODN nanocapsules on cultured tumor cells. We found that nanocapsules were capable of protecting ODN against degradation. Using confocal microscopy, we observed that cell uptake and nuclear accumulation of ODNs were importantly enhanced when ODNs were associated with these nanocapsules. Consequently, a specific cellular growth inhibition and suppression of EWSFli1 fusion gene expression was noticed. In conclusion, it was demonstrated that nanocapsules as nonviral vectors show great potential for the delivery of ODNs to cells.
Hypersonic Viscous Flow Over Large Roughness Elements (2009)

Viscous flow over discrete or distributed surface roughness has great implications for hypersonic flight due to aerothermodynamic considerations related to laminar-turbulent transition. Current prediction capability is greatly hampered by the limited knowledge base for such flows. To help fill that gap, numerical computations are used to investigate the intricate flow physics involved. An unstructured mesh, compressible Navier-Stokes code based on the space-time conservation element, solution element (CESE) method is used to perform time-accurate Navier-Stokes calculations for two roughness shapes investigated in wind tunnel experiments at NASA Langley Research Center. It was found through 2D parametric study that at subcritical Reynolds numbers of the boundary layers, absolute instability resulting in vortex shedding downstream, is likely to weaken at supersonic free-stream conditions. On the other hand, convective instability may be the dominant mechanism for supersonic boundary layers. Three-dimensional calculations for a rectangular or cylindrical roughness element at post-shock Mach numbers of 4.1 and 6.5 also confirm that no self-sustained vortex generation is present.
Isolation of the Secoiridoid-Glucoside Sweroside from Tabernaemontana psorocarpa (1982)

The known secoiridoid glucoside sweroside (structure I) has been isolated from the leaves of Tabernaemontana psorocarpa and identified by chemical, chromatographic and spectroscopical data. Its (1)H-NMR at 360 MHz is discussed.
Using constraint geometry to determine maximum rate pipeline clocking (1992)

Geometric knowledge of the shape of the feasible region formed by pulse width, setup, and hold constraints, is used directly by a new efficient (cubic complexity) algorithm, Gpipe, to determine the maximum rate for single-phase clocking of a given pipeline. The pipeline model uses level-sensitive latches as synchronizers and can allow wave pipelining. Gpipe is also used to explore the effect of removing nonsynchronizing and/or synchronizing latches on the maximum clock speed of the pipeline. A simple test shows which latches, if any, to remove to guarantee no decrease and permit a possible increase in the clock rate.
On a model-based approach to improve intranasal spray targeting for respiratory viral infections (2023)

The nasopharynx, at the back of the nose, constitutes the dominant initial viral infection trigger zone along the upper respiratory tract. However, as per the standard recommended usage protocol ("Current Use", or CU) for intranasal sprays, the nozzle should enter the nose almost vertically, resulting in sub-optimal nasopharyngeal drug deposition. Through the Large Eddy Simulation technique, this study has replicated airflow under standard breathing conditions with 15 and 30 L/min inhalation rates, passing through medical scan-based anatomically accurate human airway cavities. The small-scale airflow fluctuations were resolved through use of a sub-grid scale Kinetic Energy Transport Model. Intranasally sprayed droplet trajectories for different spray axis placement and orientation conditions were subsequently tracked via Lagrangian-based inert discrete phase simulations against the ambient inhaled airflow field. Finally, this study verified the computational projections for the upper airway drug deposition trends against representative physical experiments on sprayed delivery performed in a 3D-printed anatomic replica. The model-based exercise has revealed a new "Improved Use" (or, IU) spray usage protocol for viral infections. It entails pointing the spray bottle at a shallower angle (with an almost horizontal placement at the nostril), aiming slightly toward the cheeks. From the conically injected spray droplet simulations, we have summarily derived the following inferences: (a) droplets sized between 7-17 <i>μ</i>m are relatively more efficient at directly reaching the nasopharynx via inhaled transport; and (b) with realistic droplet size distributions, as found in current over-the-counter spray products, the targeted drug delivery through the IU protocol outperforms CU by a remarkable 2 orders-of-magnitude.
Study of Langmuir monolayers of ruthenium complexes and their aggregation by electrogenerated chemiluminescence (1991)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTStudy of Langmuir monolayers of ruthenium complexes and their aggregation by electrogenerated chemiluminescenceCary J. Miller, Paul McCord, and Allen J. BardCite this: Langmuir 1991, 7, 11, 2781–2787Publication Date (Print):November 1, 1991Publication History Published online1 May 2002Published inissue 1 November 1991https://pubs.acs.org/doi/10.1021/la00059a061https://doi.org/10.1021/la00059a061research-articleACS PublicationsRequest reuse permissionsArticle Views468Altmetric-Citations115LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Introduced Tuber aestivum spreading spontaneously in Israel (2013)

A Tuber melanosporum plantation established in 1994/5 on Kibbutz Bar'am (in the Upper Galilee, Israel, Fig. When checked in 1998, only about 70% of the trees maintained their original mycorrhiza A number of trees perished. Several different tree species were initially introduced. These included both
Optofluidic detection for cellular phenotyping (2012)

Quantitative analysis of the output of processes and molecular interactions within a single cell is highly critical to the advancement of accurate disease screening and personalized medicine. Optical detection is one of the most broadly adapted measurement methods in biological and clinical assays and serves cellular phenotyping. Recently, microfluidics has obtained increasing attention due to several advantages, such as small sample and reagent volumes, very high throughput, and accurate flow control in the spatial and temporal domains. Optofluidics, which is the attempt to integrate optics with microfluidics, shows great promise to enable on-chip phenotypic measurements with high precision, sensitivity, specificity, and simplicity. This paper reviews the most recent developments of optofluidic technologies for cellular phenotyping optical detection.
SURG-14. DOES WAITING MATTER? HOW TIME FROM DIAGNOSTIC MRI TO SURGICAL RESECTION AFFECTS OUTCOMES IN NEWLY DIAGNOSED GLIOBLASTOMA (2019)

Abstract Surgical resection is standard of care for patients with lesions concerning for high-grade glioma on MRI scan. There is no consensus on the urgency of the procedure for patients with good clinical performance status. Treatment history and functional outcomes were collected retrospectively from the electronic medical record for 105 consecutive patients with newly diagnosed WHO Grade IV gliomas who underwent surgical resection at the University of California, San Francisco in 2014 and 2015 (41% female, average age = 61.25). Median preoperative KPS score was 80. Median wait time to surgery was 11 days after the initial MRI scan (range: 0–213 days). Mean tumor volume at the time of initial MRI scan was 29.0 cm3 (SD = 26.1 cm3), which did not significantly differ from the mean pre-operative tumor volume of 31.2 cm3 (SD = 27.3 cm3). In this retrospective cohort, patients with larger glioblastomas were taken to surgery more quickly. Patients who presented to the emergency room were more likely to wait less than 7 days (p &amp;lt; 0.001). Patients who waited less than 7 days had a larger initial and pre-operative tumor volume compared to patients who waited between 7–21 days and patients who waited over 21 days (p=&amp;lt; 0.001, p=&amp;lt; 0.001). Tumor growth occurred in 10% of patients who waited one week or less, 26% of patients who waited one to three weeks, and 55% of patients who waited over 3 weeks. Overall survival was not significantly affected by wait time until tumor resection (p=0.52). Additionally, Tumor growth was not associated with postoperative outcomes including postoperative KPS score, postoperative deficits, 3-month follow up KPS score, overall survival, and survival after surgery. In conclusion, longer wait time to surgery does not impact overall survival, pre-, and post-operative KPS, but the tumor is likely to grow in the interim.
Chronic Empagliflozin Treatment Reduces Myocardial Infarct Size in Nondiabetic Mice Through STAT-3-Mediated Protection on Microvascular Endothelial Cells and Reduction of Oxidative Stress (2020)

<b><i>Aims:</i></b> Empagliflozin (EMPA) demonstrates cardioprotective effects on diabetic myocardium but its infarct-sparing effects in normoglycemia remain unspecified. We investigated the acute and chronic effect of EMPA on infarct size after ischemia-reperfusion (I/R) injury and the mechanisms of cardioprotection in nondiabetic mice. <b><i>Results:</i></b> Chronic oral administration of EMPA (6 weeks) reduced myocardial infarct size after 30 min/2 h I/R (26.5% ± 3.9% <i>vs</i> 45.8% ± 3.3% in the control group, <i>p</i> < 0.01). Body weight, blood pressure, glucose levels, and cardiac function remained unchanged between groups. Acute administration of EMPA 24 or 4 h before I/R did not affect infarct size. Chronic EMPA treatment led to a significant reduction of oxidative stress biomarkers. STAT-3 (signal transducer and activator of transcription 3) was activated by Y(705) phosphorylation at the 10th minute of R, but it remained unchanged at 2 h of R and in the acute administration protocols. Proteomic analysis was employed to investigate signaling intermediates and revealed that chronic EMPA treatment regulates several pathways at reperfusion, including oxidative stress and integrin-related proteins that were further evaluated. Superoxide dismutase and vascular endothelial growth factor were increased throughout reperfusion. EMPA pretreatment (24 h) increased the viability of human microvascular endothelial cells in normoxia and on 3 h hypoxia/1 h reoxygenation and reduced reactive oxygen species production. In EMPA-treated murine hearts, CD31-/VEGFR2-positive endothelial cells and the pSTAT-3(Y705) signal derived from endothelial cells were boosted at early reperfusion. <b><i>Innovation:</i></b> Chronic EMPA administration reduces infarct size in healthy mice <i>via</i> the STAT-3 pathway and increases the survival of endothelial cells. <b><i>Conclusion:</i></b> Chronic but not acute administration of EMPA reduces infarct size through STAT-3 activation independently of diabetes mellitus.