gebhart/patrepeval huggingface dataset:
Modeling the diffusion of grown-in Be in molecular beam epitaxy GaAs (1995)

The diffusion of Be in GaAs is studied in samples which are molecular beam epitaxy GaAs with grown-in Be. The Be diffusion profiles of samples annealed under various conditions are obtained using secondary ion mass spectrometry. SUPREM-IV.GS, a simulator for GaAs and Si processing technology, is used to compare the experimental results with our models and to extract parameters. The Be diffusion profiles show a kink feature and a time-dependent Be diffusivity which are successfully simulated. The intrinsic Be diffusivity, the Ga interstitial diffusivity, and the equilibrium concentration of Ga interstitials, all as a function of temperature, are obtained from this study: D+1Be=0.17 exp(−3.39 eV/kBT) cm2 s−1, DI=6.4×10−5 exp(−1.28 eV/kBT) cm2 s−1, and CI*int=4.7×1028 exp(−3.25 eV/kBT) cm−3. The role of nonequilibrium Ga point defects in the anomalous Be diffusion behavior is addressed.
Integration of GPS and satellite images for detection and classification of fleet hotspots (2017)

Hotspot detection and classification for a fleet of vehicles is usually performed based on GPS data sampled from the vehicles. In this paper, we explore how the integration of satellite images can improve GPS-based hotspot classification. We propose a system composed of a deep Convolutional Neural Network (CNN) for image classification and a Random Forest classifier that combines GPS-based features with the CNN output for hotspot classification. We introduce also a novel metric for scoring place detection and classification systems, able to account for both detection and classification errors. The new metric is used to assess experimentally the effectiveness of our system in combining the two sources of information.
Zavedení metodiky měření pomocí technologie 3D skenování do strojírenské výroby (2020)

Tato práce se zabývá porovnáním běžně používané metody dotykového měření s metodami 3D skenování pro jejich zavedení do strojírenské výroby. V první části je shrnutý současný stav popisem technologií měření s důrazem na 3D technologie a jejich mnohostranné využití. Druhá část předkládá praktické porovnání tří druhů měřicích zařízení na vybraném komponentu z jízdního kola. Po číselném i grafickém vyhodnocení výsledků měření jsou tyto hodnoty dále statisticky zpracovány a spočítány nejistoty měření. Závěrečná část práce zhodnocuje celý proces a uvádí praktické návrhy, možnosti a doporučení.
New findings on acrylonitrile metabolism. (1980)

The mechanism of the metabolic pathway of acrylonitrile to cyanide (and subsequently to thiocyanate which is excreted in the urine) was already previously confirmed by our work in vitro as well as in vivo. This metabolic route of AN via glycidonitrile and glycolaldehyde cyanohydrin is not the dominant pathway in the total balance of AN metabolism and does not elucidate the fate of the predominant amount of AN. By means of AN labelled with 14C on the nitrile group it was confirmed that, when different routes of administration are used, AN forms in the rat the main portion of radioactivity excreted in the urine in "non-thiocyanate" metabolites. Based on reflection on the reactivity of AN the assumption was expressed that possible metabolites of AN may be S-(2-cyanoethyl)cysteine (CEC) or N-acetyl-S-(2-cyanoethyl)cysteine (AcCEC), so called AN-mercapturic acid. Both these substances were synthetized in our laboratory and used as standards on paper chromatography of urine of animals exposed to AN. Evidence was provided that the main metabolite of AN in rats and rabbits is AcCEC. In the urine of rats 8 hours following administration of AN-14CN in addition to AcCEC another metabolite appears the structure of which was not elucidated so far. By means of preparative paper chromatography of the methylene chloride extract of rabbit urine obtained after subcutaneous injection of AN it proved possible to isolate AcCEC in the form of its dicyclohexyammonium salt. This salt did not produce a depression of the melting point with the synthetically prepared standard. This proved unequivocally the identity of the two substances.
A User Guidance Approach for Passive Haptic Environments (2008)

Traveling through virtual environments (VEs) by means of real walking is a challenging task since usually the size of the virtual world exceeds the size of the tracked interaction space. Redirected walking is one concept to solve this problem by guiding the user on a physical path which differs from the path the user visually perceives, for example, in head-mounted display (HMD) environments.The user can be redirected to certain locations in the physical space, in particular to real proxy objects which provide passive feedback. In such passive haptic environments, any number of virtual objects can be mapped to proxy objects having similar haptic properties, i. e., size, shape and texture. When the user is guided to corresponding proxy objects, s/he can sense virtual objects by touching their real world counterparts. Therefore it is vital to predict the user's movements in the virtual world in order to recognize the target location. Based on the prediction a transformed path can be determined in the physical space on which the user is guided to the desired proxy object. In this paper we present concepts how a user's path can be predicted reliably and how a corresponding path to a desired proxy object can be derived on which the user does not observe inconsistencies between vision and proprioception.
TCADMEMS Overview (2007)

This paper presents an overview of the important issues in the field of TCAD MEMS. It will be shown different techniques to investigate the materials properties of MEMS and their impact on the RF MEMS characteristics. Multi-physic simulation are presented to predict the initial deformation of MEMS based membrane and to predict the capacitive and DC contact characteristics of RF MEMS.
Expression of Autocrine Motility Factor (AMF) and Its Receptor, AMFR, in Human Breast Cancer (2005)

Autocrine motility factor (AMF) stimulates, via an autocrine route, the motility of cancer cells. The current study investigated the expression of AMF and its receptor, AMFR (gp78), in breast cancer and attempted to dissect a clinical link. Breast tumor tissues (n=120) and non-neoplastic normal tissues (n=32) were studied. AMF and AMFR distribution in tissues were assessed using immunohistochemistry and their transcripts were analyzed using RT-PCR and quantitative PCR. Median follow-up of the cohort was 10 years. Normal mammary epithelial cells, but not stromal and endothelial cells, weakly stained for AMF and AMFR. However, cancer cells showed stronger staining. Both AMF and AMFR transcripts were significantly higher in tumor than in normal tissues (p=0.003 and p=0.0001, respectively). High levels of AMF and AMFR were seen in patients who died of breast cancer (p=0.049, p=0.0435) and high AMF was also seen in patients who had local recurrence (p=0.039) compared with those who remained disease free. A significant correlation was seen between long-term survival and the AMFR:CK19 ratio, in which patients with high AMFR:CK19 ratio tumors had a significantly shorter survival (101.0 months, 80.6-121.4) compared with those with low ratio (136.0 months, 123.7-148.2), p=0.0331. In conclusion, AMF and AMFR are overexpressed in human breast cancer and are negatively associated with patients' clinical outcome. This strongly indicates that the AMF-AMFR complex plays an important role in the progression of breast cancer, as well as having a prognostic role.
Evaluation of TiN/Cu Gate Metal Scheme for AlGaN/GaN High-Electron-Mobility Transistor Application (2013)

The TiN/Cu metal scheme as gate metal for AlGaN/GaN high-electron-mobility transistors (HEMTs) is investigated. The copper-gated devices show comparable DC characteristics to the conventional Ni/Au-gated devices. No obvious of changes in IDS and IGS were observed for the device after being stressed at VDS=200 and VGS=-5 V for 32 h. The thermal stability test indicates comparable Schottky barrier height for the TiN/Cu gate metal on GaN before and after 250 °C annealing for 1 h. Overall, the AlGaN/GaN HEMT with the TiN/Cu gate metal structure demonstrates excellent device DC characteristics, good thermal stability, and stable performance after a high-voltage stress test.
Comparison of various density functional methods for distinguishing stereoisomers based on computed <sup>1</sup>H or <sup>13</sup>C NMR chemical shifts using diastereomeric penam β‐lactams as a test set (2007)

Full (1)H and (13)C NMR chemical shift assignments were made for two sets of penam beta-lactams: namely, the diastereomeric (2S, 5S, 6S)-, (2S, 5R, 6R)-, (2S, 5S, 6R)-, and (2S, 5R, 6S)-methyl 6-(1,3-dioxoisoindolin-2-yl)-3,3-dimethyl-7-oxo-4-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylates (1-4) and (2S, 5R, 6R)-, (2S, 5S, 6R)-, and (2S, 5R, 6S)-6-(1,3-dioxoisoindolin-2-yl)-3,3-dimethyl-7-oxo-4-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acids (6-8). Each penam was then modeled as a family of conformers obtained from Monte Carlo searches using the AMBER* force field followed by IEFPCM/B3LYP/6-31G(d) geometry optimization of each conformer using chloroform solvation. (1)H and (13)C chemical shifts for each conformer were computed at the WP04, WC04, B3LYP, and PBE1 density functional levels as Boltzmann averages of IEFPCM/B3LYP/6-311 + G(2d,p) energies over each family. Comparisons between experimental and theoretical chemical shift data were made using the total absolute error (|Deltadelta| (T)) criterion. For the (1)H shift data, all methods were sufficiently accurate to identify the proper stereoisomers. Computed (13)C shifts were not always successful in identifying the correct stereoisomer, regardless of which DFT method was used. The relative ability of each theoretical approach to discriminate among stereoisomers on the basis of proton shifts was also evaluated.
Biological sample measurement using a 10o tilted fiber grating sensing probe (2012)

High sensitivity biological sample measurement has been achieved by using a 10° tilted fiber Bragg grating. Human acute leukemia cells with different intracellular densities were clearly discriminated by identifying their slight refraction index (RI) perturbations in the range from 1.3342 to 1.3344, combining with a temperature self-calibration property.
Distributed top-k aggregation queries at large (2009)

Top-k query processing is a fundamental building block for efficient ranking in a large number of applications. Efficiency is a central issue, especially for distributed settings, when the data is spread across different nodes in a network. This paper introduces novel optimization methods for top-k aggregation queries in such distributed environments. The optimizations can be applied to all algorithms that fall into the frameworks of the prior TPUT and KLEE methods. The optimizations address three degrees of freedom: 1) hierarchically grouping input lists into top-k operator trees and optimizing the tree structure, 2) computing data-adaptive scan depths for different input sources, and 3) data-adaptive sampling of a small subset of input sources in scenarios with hundreds or thousands of query-relevant network nodes. All optimizations are based on a statistical cost model that utilizes local synopses, e.g., in the form of histograms, efficiently computed convolutions, and estimators based on order statistics. The paper presents comprehensive experiments, with three different real-life datasets and using the ns-2 network simulator for a packet-level simulation of a large Internet-style network.
Gait analysis using ultrasound and inertial sensors (2015)

Introduction and past research: Inertial sensors are great for orientation estimation, but they cannot measure relative positions of human body segments directly. In previous work we used ultrasound to estimate distances between body segments [1]. In [2] we presented an easy to use system for gait analysis in clinical practice but also in-home situations. Ultrasound range estimates were fused with data from foot-mounted inertial sensors, using an extended Kalman filter, for 3D (relative) position and orientation estimation of the feet. Validation: From estimated 3D positions we calculated step lengths and stride widths and compared this to an optical reference system for validation. Mean (±standard deviation) of absolute differences was 1.7 cm (±1.8 cm) for step lengths and 1.2 cm (±1.2 cm) for stride widths when comparing 54 walking trials of three healthy subjects. Clinical application: Next, the system presented in [2] was used in the INTERACTION project, for measuring eight stroke subjects during a 10 m walk test [3]. Step lengths, stride widths and stance and swing times were compared with the Berg balance scale score. The first results showed a correlation between step lengths and Berg balance scale scores. To draw real conclusions, more patients and also different activities will be investigated next. Future work: In future work we will extend the system with inertial sensors on the upperand lower legs and the pelvis, to be able to calculate a closed loop and improve the estimation of joint angles compared with systems containing only inertial sensors.
Self-potential and spectral induced polarization signals associated with microbial sulphate reduction (2009)

Self-potential and spectral induced polarization responses associated with microbial processes involved in sulphate reduction have been monitored in a Perspex Winogradsky column filled with glass beads and growth medium. Salt-bridge is utilized as an electrolytic contact between experiment and control column. Equally spaced SP electrodes are used in combination of Ag-AgCl electrodes to compare electrodic and SP signals associated with the microbial processes involved in sulphate reduction. This study reveals that magnitude of SP varies from 5 to -2 mV and Electrodic potential 0 to -20 mV at the time of domination (day 39) of sulphate reducing bacteria which are very small in comparison to those measured by fixing both measuring and reference Ag-AgCl electrodes in experiment column. We observed that real and imaginary parts of complex conductivities increase with increase in production of H2S and CO in the experiment column. Both real and imaginary parts of surface complex conductivity vary at low frequencies similar to typical growth curve of bacterial population. Sodium lactate as a carbon source, dissolved in Lagan River water was flushed into the column for biostimulation on 144th day. The dissolved oxygen in flushed fluid might have killed the anaerobes in the column and decrease in complex conductivities similar to death phase of bacteria is observed for one week. The results obtained from this experiment should contribute to further understanding the biogeophysical responses involved in complex environments.
A Design Methodology for High-Speed Low-Power MCML Frequency Dividers (2006)

A strategy to design high-speed low-power MOS Current-Mode Logic (MCML) static frequency dividers is here proposed. Analytical criteria to exploit the speed potential of MCML gates are first introduced. Then, analytical criteria are formulated to progressively reduce the bias currents through the stages without affecting the divider operation speed, reducing the overall power consumption. The analytical approach allows for a deeper understanding of the power-delay trade-off involved in the design. In order to validate the theoretical derivations, SPICE simulation results on a 1:8 frequency divider by using a 0.18-μm CMOS process are given.
Metribuzin metabolites in mammals and liver microsomal oxidase systems: identification, synthesis, and reactions (1984)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTMetribuzin metabolites in mammals and liver microsomal oxidase systems: identification, synthesis, and reactionsMarian Saeman Bleeke and John E. CasidaCite this: J. Agric. Food Chem. 1984, 32, 4, 749–755Publication Date (Print):July 1, 1984Publication History Published online1 May 2002Published inissue 1 July 1984https://pubs.acs.org/doi/10.1021/jf00124a012https://doi.org/10.1021/jf00124a012research-articleACS PublicationsRequest reuse permissionsArticle Views117Altmetric-Citations8LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Multifunctional Hierarchically Assembled Nanostructures as Complex Stage-Wise Dual-Delivery Systems for Coincidental Yet Differential Trafficking of siRNA and Paclitaxel (2013)

Development of multifunctional nanostructures that can be tuned to codeliver multiple drugs and diagnostic agents to diseased tissues is of great importance. Hierarchically assembled theranostic (HAT) nanostructures based on anionic cylindrical shell cross-linked nanoparticles and cationic shell cross-linked knedel-like nanoparticles (cSCKs) have recently been developed by our group to deliver siRNA intracellularly and to undergo radiolabeling. In the current study, paclitaxel, a hydrophobic anticancer drug, and siRNA have been successfully loaded into the cylindrical and spherical components of the hierarchical assemblies, respectively. Cytotoxicity, immunotoxicity, and intracellular delivery mechanism of the HAT nanostructures and their individual components have been investigated. Decoration of nanoparticles with F3-tumor homing peptide was shown to enhance the selective cellular uptake of the spherical particles, whereas the HAT nanoassemblies underwent an interesting disassembly process in contact with either OVCAR-3 or RAW 264.7 cell lines. The HAT nanostructures were found to "stick" to the cell membrane and "trigger" the release of spherical cSCKs templated onto their surfaces intracellularly, while retaining the cylindrical part on the cell surface. Combination of paclitaxel and cell-death siRNA (siRNA that induces cell death) into the HAT nanostructures resulted in greater reduction in cell viability than siRNA complexed with Lipofectamine and the assemblies loaded with the individual drugs. In addition, a shape-dependent immunotoxicity was observed for both spherical and cylindrical nanoparticles with the latter being highly immunotoxic. Supramolecular assembly of the two nanoparticles into the HAT nanostructures significantly reduced the immunotoxicity of both cSCKs and cylinders. HAT nanostructures decorated with targeting moieties, loaded with nucleic acids, hydrophobic drugs, radiolabels, and fluorophores, with control over their toxicity, immunotoxicity, and intracellular delivery might have great potential for biomedical delivery applications.
Comparative effects of adaptation on layers <scp>II</scp>–<scp>III</scp> and V–<scp>VI</scp> neurons in cat V1 (2016)

V1 is fundamentally grouped into columns that descend from layers II-III to V-VI. Neurons inherent to visual cortex are capable of adapting to changes in the incoming stimuli that drive the cortical plasticity. A principle feature called orientation selectivity can be altered by the presentation of non-optimal stimulus called 'adapter'. When triggered, LGN cells impinge upon layer IV and further relay the information to deeper layers via layers II-III. Using different adaptation protocols, neuronal plasticity can be investigated. Superficial neurons in area V1 are well acknowledged to exhibit attraction and repulsion by shifting their tuning peaks when challenged by a non-optimal stimulus called 'adapter'. Layers V-VI neurons in spite of partnering layers II-III neurons in cortical computation have not been explored simultaneously toward adaptation. We believe that adaptation not only affects cells specific to a layer but modifies the entire column. In this study, through simultaneous multiunit recordings in anesthetized cats using a multichannel depth electrode, we show for the first time how layers V-VI neurons (1000-1200 μm) along with layers II-III neurons (300-500 μm) exhibit plasticity in response to adaptation. Our results demonstrate that superficial and deeper layer neurons react synonymously toward adapter by exhibiting similar behavioral properties. The neurons displayed similar amplitude of shift and maintained equivalent sharpness of Gaussian tuning peaks before and the following adaptation. It appears that a similar mechanism, belonging to all layers, is responsible for the analog outcome of the neurons' experience with adapter.
Coarse-grained modeling of DNA curvature (2014)

The interaction of DNA with proteins occurs over a wide range of length scales, and depends critically on its local structure. In particular, recent experimental work suggests that the intrinsic curvature of DNA plays a significant role on its protein-binding properties. In this work, we present a coarse grained model of DNA that is capable of describing base-pairing, hybridization, major and minor groove widths, and local curvature. The model represents an extension of the recently proposed 3SPN.2 description of DNA [D. M. Hinckley, G. S. Freeman, J. K. Whitmer, and J. J. de Pablo, J. Chem. Phys. 139, 144903 (2013)], into which sequence-dependent shape and mechanical properties are incorporated. The proposed model is validated against experimental data including melting temperatures, local flexibilities, dsDNA persistence lengths, and minor groove width profiles.
A Review of the Admission System for Mental Disorders in South Korea (2020)

This study presents a comprehensive overview of the characteristics of mental health problems and admission system in South Korea. We compared the mental health-related indicators data from South Korea to data from other Organization for Economic Cooperation and Development (OECD) countries. South Korea was identified as the country with the highest suicide rate, the longest length of stay in hospitals for mental disorders, and the highest number of psychiatric care beds. These results can be explained by considering the admission system for mental disorders. We reviewed the admission system and the Mental Health Promotion and Welfare Act, providing direction for improving the system.