gebhart/patrepeval huggingface dataset:
Simulation of transient effects in a fuel injector nozzle using real-fluid thermodynamic closure (2021)

Numerical predictions of the fuel heating and cavitation erosion location indicators occurring during the opening and closing periods of the needle valve inside a five-hole common rail Diesel fuel injector are presented. These have been obtained using an explicit density-based solver of the compressible Navier-Stokes (NS) and energy conservation equations; the flow solver is combined with two thermodynamic closure models for the liquid, vapour and vapour-liquid equilibrium (VLE) property variation as function of pressure and temperature. The first is based on tabulated data for a 4-component Diesel fuel surrogate, derived from the Perturbed-Chain, Statistical Associating Fluid Theory (PC-SAFT) Equation of State (EoS), allowing for the variation of the physical and transport properties of the fuel with the local pressure and temperature to be quantified. The second thermodynamic closure is based on the widely used barotropic Equation of State (EoS) approximation between density and pressure only and neglects viscous heating. The Wall Adapting Local Eddy viscosity (WALE) LES model was used to resolve sub-grid scale turbulence while a cell-based mesh deformation Arbitrary Lagrangian–Eulerian (ALE) formulation is used for modelling the injector's needle valve movement. Model predictions are found in close agreement against 0-D estimates of the temporal variation of the fuel temperature difference between the feed and hole exit during the injection period. Two mechanisms affecting the temperature distribution within the fuel injector have been revealed and quantified. The first is ought to wall friction-induced heating, which may result to local liquid temperature increase up to fuel's boiling point while superheated vapour is formed. At the same time, liquid expansion due to the depressurisation of the injected fuel results to liquid cooling relative to the fuel's feed temperature; this is occurring at the central part of the injection orifice. The spatial and temporal temperature and pressure gradients induce significant variations in the fuel density and viscosity, which in turn, affect the formed coherent vortical flow structures. It is found, in particular, that these affect the locations of cavitation formation and collapse, that may lead to erosion of the surfaces of the needle valve, sac volume and injection holes. Model predictions are compared against corresponding X-ray surface erosion images obtained from injector durability tests, showing good agreement.
Cryotomography x-ray microscopy state (2023)

An x-ray microscope stage enables alignment of a sample about a rotation axis to enable three dimensional tomographic imaging of the sample using an x-ray microscope. A heat exchanger assembly provides cooled gas to a sample during x-ray microscopic imaging.
Distortion-invariant pattern recognition with Fourier-plane nonlinear filters (1996)

The use of nonlinear techniques in the Fourier plane of pattern-recognition correlators can improve the correlators' performance in terms of discrimination against objects similar to the target object, correlation-peak sharpness, and correlation noise robustness. Additionally, filter designs have been proposed that provide the linear correlator with invariance properties with respect to input-signal distortions and rotations. We propose simple modifications to presently known distortion-invariant correlator filters that enable these filter designs to be used in a nonlinear correlator architecture. These Fourier-plane nonlinear filters can be implemented electronically, or they may be implemented optically with a nonlinear joint transform correlator. Extensive simulation results are presented that illustrate the performance enhancements that are gained by the unification of nonlinear techniques with these filter designs.
&lt;title&gt;Piecewise approach of maximum-likelihood receiver&lt;/title&gt; (2002)

A receiver structure referred to as piecewise maximum likelihood (PML) is proposed in order to reduce the complexity of the PRML receiver. A channel response of optical disk is used for the performance evaluation. The channel distortion such as tangential tilt effect of optical disk also considered. The hardware implementation complexity between the PML and adaptive PRML is compared.
Effect of Extracorporeal Blood Purification on Mortality in Sepsis: A Meta-Analysis and Trial Sequential Analysis (2020)

There are inadequate data at present to conclude that the use of extracorporeal blood purification techniques in sepsis is beneficial. Further adequately powered RCTs are required to confirm any potential mortality benefit, which may be most evident in patients at greatest risk of death.
Effect of Bulk Density on Reaction Propagation in Nanothermites and Micron Thermites (2009)

The thermite reaction of nanoscale aluminum and molybdenum trioxide particles has revealed a paradoxical relationship between Al particle size and mixture bulk density. Specifically, with micron-scale Al particles, the thermite demonstrates an expected growth in flame speed with increased density, but nanoscale-Al-particle mixtures exhibit an opposing trend. This paper presents new experimental measurements of the thermal properties of this thermite as a function of Al particle size and applies a new oxidation mechanism in an effort to explain the paradoxical results between Al particle size and mixture bulk density. Results show that the nanocomposite's behavior is consistent with a new melt-dispersion oxidation mechanism and convective mode of flame propagation. Compaction-induced damage of the oxide shell and distortion of the shape of spherical particles, as well as reduced free space around Al nanoparticles suppress the melt-dispersion mechanism and reduce flame speed. An additional mode of energy transfer is proposed that is associated with molten Al clusters from the melt-dispersion mechanism that advance faster than the flame velocity. Micron-scale particle reactions may be governed by diffusion such that increased bulk density coincides with increased thermal properties and increased flame speeds.
Cost of adverse events during treatment with everolimus plus exemestane or single-agent chemotherapy in patients with advanced breast cancer in Western Europe (2014)

The current model estimates that AE management during the treatment of HR+ advanced breast cancer will cost one-half to one-third less for EVE + EXE patients than for chemotherapy patients. The consideration of AE costs could have important implications in the context of healthcare spending for advanced breast cancer treatment.
Testing The High-Energy Prompt Neutron Signature At Low Beam Energies (2011)

Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter Facebook Reddit LinkedIn Tools Icon Tools Reprints and Permissions Cite Icon Cite Search Site Citation Scott J. Thompson, Mathew T. Kinlaw, Alan W. Hunt; Testing The High‐Energy Prompt Neutron Signature At Low Beam Energies. AIP Conference Proceedings 1 June 2011; 1336 (1): 483–486. https://doi.org/10.1063/1.3586146 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAIP Publishing PortfolioAIP Conference Proceedings Search Advanced Search |Citation Search
Susceptibility of LC3B knockout mice to lung injury and fibrosis (2018)

Idiopathic pulmonary fibrosis (IPF) is a disease with a remarkable age-related onset which may be triggered by chronic lung alveolar epithelial cell type II (AECII) injury and apoptosis. AECII are classical secretory cells which contain lamellar bodies that are lysosome related organelles and are primarily responsible to store and secrete lung surfactant. Recently, the principle role of autophagy, a lysosome dependent protein quality control mechanism has been studied in the development of lung fibrosis, both in humans as well as in animal models. Yeast Atg8 or mammalian microtubule-associated protein 1 light chain 3 beta (MAP1LC3B/LC3B) isan important autophagy related protein and its lipidated form, LC3BII is a reliable marker of the autophagosomes. In this study, we aim to decipher the involvement of this protein in the development of lung fibrosis. A systematic analysis of the LC3B-/- mice lungs revealed that aged LC3B-/- mice showed increased cellularity, smaller lamellar body profiles, increased apoptosis of AECII paralleled with surfactant alterations, increased lysosomal and endoplasmic reticulum stress providing clues on the importance of this distal autophagy protein in lung fibrosis development. Further, in vitro knockdown of LC3B sensitized mouse lung epithelial cells to bleomycin induced apoptosis. In vivo, LC3B-/- mice displayed increased susceptibility to bleomycin induced lung injury and fibrosis. We conclude that LC3B plays essential roles in AECII and protects the alveolar epithelial cells from bleomycin induced lung injury and fibrosis.
Glycolytic competence in gastric adenocarcinomas negatively impacts survival outcomes of patients treated with salvage paclitaxel-ramucirumab (2020)

Glycolytic proficiency may negatively affect survival outcomes of metastatic gastric cancer patients treated with PR systemic therapy. TP53 mutational status alone does not seem to explain such a metabolic shift.
Chemical routes to synthesize lithium cobalt oxide powders for rechargeable lithium batteries (1996)

Lithium cobalt oxide (LiCoO{sub 2}) is known to be a good cathode material for high voltage (4V) rechargeable Li-ion batteries. New chemical routes based on aqueous solution chemistry have been developed to synthesize molecularly mixed precursors that transform to form LiCoO{sub 2} at temperatures as low as 400{degrees}C. The resultant oxide powders are nanocrystalline ({approx} 20-40 nm) and exhibit unique morphologies and microstructures depending on the molecular environment of the ions in solution. Cathodes fabricated from the oxide powders and tested in {open_quote}hockey-puck{close_quote} test cells exhibited specific capacities of about 135 mAh/g with a reversible range close to 0.5 Li ions. Results of the phase evolution and microstructural analysis are discussed in relation to the electrochemical performance of the cathodes.
Cryogenic properties of a diamond sample at microwave frequencies (2010)

Dielectric resonators are key components for many microwave and millimetre wave applications, including high-Q filters and frequency-determining elements for precision frequency synthesis. Multilayered, bulk low-loss crystal and polycrystalline dielectric structures have become very important for designing these devices. Proper design requires careful electromagnetic characterisation of low-loss material properties. This includes exact simulation with precision numerical software and precise measurements of resonant modes. Diamond has been recently utilized for an increasing amount of electronic applications. This paper will present the common techniques for characterizing such dielectric samples in the microwave regime, and apply it to the characterization of diamond from 35 to 330K.
Effect of Atomic Hydrogen Exposure on Electron Beam Polarization from Strained GaAs photocathodes (2013)

Abstract. Strained-layer GaAs photocathodes are used at Jefferson Lab to obtain highly polarized electrons. Exposure to atomic hydrogen (or deuterium) is used to clean the wafer surface before the activation with cesium and nitrogen trifluoride to consistently produce high quantum yield photocathodes. The hydrogen-cleaning method is easy, reliable and inexpensive. However, recent tests indicate that exposure to atomic hydrogen may affect the polarization of the electron beam. This paper presents preliminary results of a series of tests conducted to study the effect of atomic H exposure on the polarized electron beam from a strained–layer GaAs sample. The experimental setup is described and the first measurements of the beam polarization as a function of exposure dose to atomic hydrogen are presented.
Demonstration of error-free 25Gb/s duobinary transmission using a colourless reflective integrated modulator (2013)

To realise novel, low-cost, photonic technologies that can support 100Gb/s Ethernet in next-generation dense wavelength-division-multiplexed metro transport networks, we are developing arrayed photonic integrated circuits that leverage colourless reflective modulators. Here, we demonstrate a single-channel, hybrid reflective electroabsorption modulator-based device, showing error-free 25.3Gb/s duobinary transmission with bit-error rates less than 1 × 10(-12) over 35km of standard single-mode fibre. We further confirm the modulator's colourless operation over the ITU C-band, with a 1.2dB variation in required optical signal-to-noise ratio over this wavelength range.
Combined Epidura/General Anesthetic Technique and Severe Coronary Artery Stenosis (1994)

Department of Anesthesiology Dartmouth-Hitchcock Medical Centet Lebanon, NH 03756–0001 (Mary) Section of Vascular Surgery Dartmouth-Hitchcock Medical Centet Lebanon, NH 03756–0001 (Mark)
Bi-level video (2001)

The rapid development of wired and wireless networks tremendously facilitates communications between people. However, most of the current wireless networks still work in low bandwidths, and mobile devices still suffer from weak computational power, short battery lifetime and limited display capability. We developed a very low bit-rate bi-level video coding technique, which can be used in video communications almost anywhere, anytime on any device. The spirit of this method is that rather than giving highest priority to the basic colors of an image as in conventional DCT-based compression methods, we give preference to the outline features of scenes when we have limited bandwidths. These features can be represented by bi-level image sequences that are converted from gray-scale image sequences. By analyzing the temporal correlation between successive frames and flexibilities in the scene presentation using bi-level images, we achieve very high ratios with our bi-level video compression scheme. Experiments show that in low bandwidths, our method provides clearer shape, smoother motion, shorter initial latency and much cheaper computational cost than do DCT-based methods. Our method is especially suitable for small mobile devices such as handheld PCs, palm-size PCs and mobile phones that possess small display screens and light computational power, and work in low bandwidth wireless networks. We have built PC and Pocket PC versions of bi-level video phone systems, which typically provide QCIF-size video with a frame rate of 5-15 fps for a 9.6 Kbps bandwidth.
Innovative immunological assays for diagnosis of Schistosoma mansoni for clinical acute and/or chronic forms (2013)

Control constraints of schistosomiasis include the lack of diagnostic methods with high sensitivity. We initiated a prospective study in southeast Brazil in order to develop sensitive diagnostic methods for Schistosoma mansoni infection, with 3 endemic areas together with 84 travelers infected in a freshwater pool. Sera samples from all those patients are used for the standardization of innovative methods for schistosomiasis mansoni. Comparisons are performed with eggs in feces, IgG titers, encephalomyelitis by NMR and clinical symptoms. We could diagnose acute patients 10 days post‐infection and also more than 95% of positive cases from chronic and low endemicity patients. New methods for IgG detection using purified glycoprotein or recombinant protein or peptides (10 aminoacids) were superior to conventional ELISA. Best results were seen for recombinant protein with 100% of sensitivity. Lastly, monoclonal antibodies were produced for improvement of the new methods by promoting direct diagnosis. Data showed 100% of sensitivity of chronic patients and 98% of acute patients. Financial support: Fapemig, CNPq, Capes, Fiocruz, Fiotec, PDTIS (Brazil). Fulbright, NIH, University of Georgia (USA).
"Contingent Engagement: A Recent Painting" Exhibition Brochure (2009)

This brochure was scanned in the VRC during summer 2014. The original may be viewed in the College Archives.
Unraveling the Shed of Unexplored Rhizosphere Microbial Diversity (2013)

The rhizosphere is the region around the plant roots which harbors a wide array of microbial populations, including bacteria and fungi which may be beneficial, neutral, or detrimental to plant growth. Among the different groups of microbes which colonize the rhizosphere, plant root–beneficial microbe interactions are very important both economically and ecologically. One of the major difficulties that microbiologists face when studying these root-associated microbial communities is that many groups of microbes that dwell in this zone are not cultivable in the laboratory. Recent developments in molecular biology methods are shedding some light on rhizospheric microbial diversity. This chapter discusses recent findings and future challenges to uncover the enormous microbial diversity in the rhizosphere.
Asymmetric type-II photocyclization of acrylylureas (1992)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAsymmetric type-II photocyclization of acrylylureasShigeo Kohmoto, Thomas Kreher, Yoshiyuki Miyaji, Makoto Yamamoto, and Kazutoshi YamadaCite this: J. Org. Chem. 1992, 57, 12, 3490–3492Publication Date (Print):June 1, 1992Publication History Published online1 May 2002Published inissue 1 June 1992https://pubs.acs.org/doi/10.1021/jo00038a047https://doi.org/10.1021/jo00038a047research-articleACS PublicationsRequest reuse permissionsArticle Views175Altmetric-Citations19LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
Re-analysis by fluorescencein situ hybridisation of spare embryos cultured until Day 5 after preimplantation genetic diagnosis for a 47, XYY infertile patient demonstrates a high incidence of diploid mosaic embryos: a case report (2000)

Mosaicism in 4-8-cell human embryos analysed by fluorescence in situ hybridisation (FISH) has been widely reported, but few studies have addressed the incidence of mosaicism in more advanced embryonic stages. In the present study we analysed spare human embryos in a case of preimplantation genetic diagnosis (PGD) for increased risk of aneuploidy because of an infertile 47,XYY man. After replacement of two embryos typed as 1818XX at PGD, six spare embryos (not frozen because of their low quality) were re-analysed on Day 5 for PGD confirmation. Out of five embryos typed as 1818XY at PGD, four were diploid mosaic (DM) and one was normal in all cells. The sixth embryo, typed as 18XYY/1818181818X at PGD, was a DM. In spite of the bias of our small series of morphologically low-quality embryos, the surprisingly high proportion of mosaics (which confirms previous findings) questions the validity of PGD, but supports the strategy of transferring only the embryos where two blastomeres gave normal and concordant results at PGD. More data are required to understand the clinical significance of early diploid mosaicism (and its impact on implantation rate) and to determine whether some diploid mosaic embryos might be considered safe for transfer.
Improving Adsorptive Performance of CaO for High-Temperature CO<sub>2</sub> Capture through Fe and Ga Doping (2019)

Calcium oxide is an efficient adsorbent for high-temperature CO2 capture process, however, it suffers from rapid deactivation and capacity loss after a few cycles as a result of particle sintering. Metal oxide doping is an effective strategy to address the durability issue of CaO. In this investigation, we report development of novel metal oxide-doped CaO adsorbents with high capture capacity, fast kinetics, and long-term stability. In particular, Fe and Ga with varied concentrations were used as promoters to improve the adsorption performance of CaO adsorbent. The doped adsorbents comprising of 10% Fe@CaO and 10% Ga@CaO exhibited the highest adsorption capacities of 13.7 and 14.2 mmol/g, respectively, at 650 °C, which were at least 2-folds higher than that of the bare CaO. Moreover, the doped-CaO materials showed reversible performance by desorbing almost all of the adsorbed CO2 during desorption step at the same temperature. Through in situ X-ray diffraction measurements, it was shown that the carbonation under CO2 and desorption under N2 flow take place, resulting in efficient CO2 capture and adsorbent regeneration. The cyclic adsorption–desorption runs demonstrated the excellent stability of the materials by retaining 95% of their initial capacity after 10 cycles. Moreover, adsorption temperature was found to have a favorable impact on CO2 uptake over the doped adsorbents. The findings of this study highlight the feasibility of metal doping approach for improving the adsorptive performance of CaO adsorbents that could be used for high-temperature capture processes.
Metataxonomic and Metabolic Impact of Fecal Microbiota Transplantation From Patients With Pancreatic Cancer Into Germ-Free Mice: A Pilot Study (2021)

In this pilot study, FMT from PC patients was associated with a decrease in visceral fat as compared to FMT from healthy individuals. Some of the differences in fecal microbiota between PC and control samples are common to humans and mice. Further research is required to confirm that feces contain elements involved in metabolic and immune alterations.
Role of Myocilin in Glaucoma : Molecular Defects and Possible Functional Aberrations Leading to Pathogenesis (2006)

Glaucoma is a heterogeneous group of optic neuropathies, with a complex genetic basis. Among the established candidate genes known to be involved in the disease, myocilin has been reported to cause a small percentage of adult onset and a major percentage of juvenile onset cases of glaucoma. Mutations in different regions of the gene have been found to be associated with a wide spectrum of glaucoma phenotypes. The gene has also been implicated in primary congenital glaucoma as well as in digenic cases of the disease. The article intends to explore the functional aspects of the protein in normal trabecular meshwork (TM) and molecular basis of TM cell dysfunction as a result of mutation in the protein as revealed from the current studies. We also report occurrence in an Indian POAG family a mutation (Q368X), common among Caucasians, and the studies in progress on myocilin-related genes that could serve as candidates for glaucoma.