gebhart/patrepeval huggingface dataset:
Negative-type chemically amplified resists for ArF excimer laser lithography (1998)

A new negative resist consisting of an anhydride, an acrylic acid, an epoxy crosslinker and a photoacid generator is introduced. In the exposed area, the epoxy groups of the crosslinker react with anhydride groups and/or carboxylic acids in the polymer under existence of photogenerated acid as a catalyst during post exposure baking. A 0.20 micrometers pattern was resolved by an ArF exposure at a dose of 28 mJ/cm<SUP>2</SUP>.
Fibers with resonant mode suppression (2007)

Noise can limit the power in a fiber amplifier by competing with the signal for gain. Disributed filtering offers a way of overcoming current high-power limitations by selectively removing noise before it is amplified. Resonant mode suppression is a flexible strategy for wavelength filtering as well as suppression of unwanted transverse modes. An Yb-doped gain fiber with distributed filtering of stimulated Raman scattering (SRS) was demonstrated in a cladding-pumped amplifier. Substantial suppression of SRS was demonstrated in this fiber, with a core and resonant Ge-doped ring made using standard solid-fiber fabrication. Simulations explore generalizations to large-mode-area and filters with multiple band-stop features.
Cervical spine stabilization. A three-dimensional, biomechanical evaluation of rotational stability, strength, and failure mechanisms. (1991)

The three-dimensional rotational biomechanical properties of several different types of posterior stabilizing procedures are reported. A severe ligamentous and bony injury was simulated with three vertebral body human cervical spine segments. Good stabilization was noted for all of the repairs in flexion loading. Without polymethylmethacrylate supplementation, none of the repairs was stable in extension. All of the repairs provided reasonable stabilization for lateral bending except for the posterior wiring without methacrylate, and all but the posterior wiring and facet fusion provided reasonable stabilization against axial rotation loading. The supplementation of all of these repairs with polymethylmethacrylate added considerably to the stability of all the constraints. These findings may be useful in clinical decision-making for determining the kind of repairs and postoperative brace protection to use.
Supplemental Figure 1: HLAII-DR molecule accumulates at the periphery of DCs after 12 hours incubation from Microvesicle Cargo of Tumor-Associated MUC1 to Dendritic Cells Allows Cross-presentation and Specific Carbohydrate Processing (2023)

&lt;p&gt;Cellular distribution of HLAII-DR molecules in iDCs was visualized after 2 or 12 hours from cell harvesting and incubation at 37{degree sign}C (columns 1 and 2, respectively) by immunofluorescence staining by Apotome module employing the anti-HLA-DR MoAb L243 (red signal). Nuclei are visualized in blu DAPI staining. Magnification 60X; Bars: 10μm.&lt;/p&gt;
Range Estimation of a Moving Target Using Ultrasound Differential\n Zadoff-Chu Codes (2021)

High accuracy range estimation is an essential tool required in many modern\napplications and technologies. However, continuous range estimation of a moving\ntarget is a challenging task, especially under Doppler effects. This paper\npresents a novel signal design, which we name differential Zadoff-Chu (DZC).\nUnder Doppler effects, DZC sequences improve the performance of the maximum\nlikelihood (ML)-based range estimation compared to its performance when using\nregular ZC sequences. Moreover, a reduced-complexity ranging algorithm is\nproposed utilizing DZC sequences and is shown to outperform the regular ZC\nML-based range estimation. The proposed system is evaluated in a typical indoor\nenvironment, using low-cost ultrasound hardware. Under a low signal to noise\nratio (-10 dB SNR), more than 90% of the range estimates are in less than 1.6\nmm error, with a movement range from $0.2$ m to 2.2 m and a maximum velocity of\n0.5 m/s. For the same movement range, the system provides range estimates with\na root mean square error (RMSE) less than 0.76 mm in a high SNR scenario (10\ndB), and an MSE less than 0.85 mm in a low SNR scenario (-10 dB). For a larger\nmovement range from 1.8 m to 4.2 m with a maximum velocity of 1.91 m/s, the\nproposed system provides range estimates with RMSE less than 7.70 mm at 10 dB\nSNR.\n
Arsenic sulphide athermal singlets for 3- to 5-μm imaging (1997)

An arsenic trisulphide refractive plus diffractive hybrid element is both achromatic and athermal across the 3 - 5 micrometer waveband when set in an aluminum mount. We present two possible ways of manufacturing this element: using a photodarkening process to realize the diffractive structures, and by diamond turning, initially not thought to be viable. We demonstrate that the required depths in the diffractive surface are obtainable by both methods, and consider the advantages of each. Above all, however this lens is fabricated it offers, a very low cost, light weight solution to athermal singlet imaging in the 3 - 5 micrometer waveband.
The principle of parsimony: Glasgow Coma Scale score predicts mortality as well as the APACHE II score for stroke patients. (1990)

Although the development and use of severity-of-illness measures has gained widespread enthusiasm, uncertainty remains as to the optimal measure for stroke patients. The Health Care Financing Administration recently derived a severity-of-illness measure based on the APACHE II system to explain differences in Medicare mortality rates among hospitals treating stroke patients. We hypothesized that the Glasgow Coma Scale score provides prognostic information of accuracy comparable to that of the APACHE II score for stroke patients, yet is simpler and cheaper to abstract from the medical record. We therefore studied 246 patients hospitalized with stroke, including 49 oversampled mortalities. The Glasgow Coma Scale score was as accurate as the APACHE II score in predicting stroke mortality both before (r = -0.50 and r = 0.50, respectively) and after (r = -0.40 and r = 0.38, respectively) the oversampled mortalities were excluded. The APACHE II score required abstraction of 16 variables from the medical record compared with three for the Glasgow Coma Scale score and required more than three times the time to abstract from the medical record. Therefore, in the interest of parsimonious data collection, the Glasgow Coma Scale may be a preferable severity-of-illness measure for patients with stroke.
Chromatographic pattern of extrapancreatic glucagon and glucagon-like immunoreactivity before and during stimulation by epinephrine and participation of glucagon in epinephrine-induced hepatic glucose overproduction. (1981)

To characterize the glucagon released in response to epineephrine in depancreatized dogs, plasma samples before and during epinephrine infusion were subjected to molecular-sieve chromatography on Bio-Gel P-30 columns. The chromatographic profile for extrapancreatic immunoreactive glucagon (eIRG) revealed two glucagon moieties of molecular weight 9,000 to 12,000. GLI of this molecular weight was released in response to epinephrine only under conditions of prevailing hyperglycemia. To determine if glucagon's participation in epinephrine-induced hepatic glucose overproduction in diabetes was dependent upon the degree of metabolic control, six conscious depancreatized dogs were infused with epinephrine or epinphrine plus somatostatin, under conditions of prevailing hyperglycemia or normoglycemia. Under normoglycemic conditions, epinephrine stimulated eIRG release, but there was a similar rise in hepatic glucose production (Ra) with or without glucagon suppression by somatostatin. Under hyperglycemic conditions, epinephrine stimulated eIRG and GLI release, and the rise in Ra was significantly greater with epinephrine than with epinephrine plus somatostatin infusion. Thus, under conditions of good metabolic control, epinephrine increased hepatic glucose production independently of glucagon, whereas with poor metabolic control, glucagon contributed to hepatic overproduction of glucose.
Investigation of the interfacial tension between steel and commercial slag for the optimization of casting in the Swedish steel industry (2005)

Investigation of the interfacial tension between steel and commercial slag for the optimization of casting in the Swedish steel industry
Alternative mRNA is favored by the A3 haplotype of the EPCR gene PROCR and generates a novel soluble form of EPCR in plasma (2007)

The endothelial cell protein C receptor also exists in soluble form in plasma (sEPCR), resulting from ADAM17 cleavage. Elevated sEPCR levels are observed in subjects carrying the A3 haplotype, which is characterized by a Ser219Gly substitution in the transmembrane domain, rendering the receptor more sensitive to cleavage. Because sEPCR production is not completely blocked by metalloprotease inhibition, we looked for another mechanism. Comparing mRNA expression patterns and levels in A3 and non-A3 cells from 32 human umbilical cord veins, we detected a truncated mRNA in addition to the full-length mRNA. This truncated mRNA was 16 times more abundant in A3 human umbilical vein endothelial cells than in non-A3 human umbilical vein endothelial cells and encoded a protein lacking the transmembrane domain. We stably expressed a recombinant form of this protein (rEPCRisoform) and a protein mimicking the plasma sEPCR (rEPCRsol). Functional studies of the purified recombinant proteins revealed that the rEPCRisoform bound to recombinant protein C with similar affinity than rEPCRsol and that it also inhibited the anticoagulant activity of APC. Trace amounts of the EPCR isoform were found in the plasma of A3 subjects. These results suggest that the sEPCRisoform could contribute to the regulatory effect of sEPCR in plasma.
Note: Heated sample platform for <i>in situ</i> temperature-programmed XPS (2011)

We present the design, fabrication, and performance of the multi-specimen heated platform for linear in situ heating during the Temperature-Programmed XPS (TPXPS). The platform is versatile, compatible with high vacuum (HV) and bakeout. The heater platform is tested under in situ linear heating of typical high surface area sorbent∕catalyst support--nanoporous TiO(2). The platform allows the TPXPS of multiple samples located on specimen disk that can be transferred in and out of the TPXPS chamber. Electric characteristics, temperature and pressure curves are provided. Heating power supply, PID temperature controller, data-logging hardware and software are described.
Expanding the Scope of Oligo-pyrrolinone–Pyrrolidines as Protein–Protein Interface Mimics (2013)

Oligo-pyrrolinone-pyrrolidines (generic structure 1) have the potential to interfere with protein-protein interactions (PPIs), but to reduce this to practice it is necessary to be able to synthesize these structures with a variety of different side chains corresponding to genetically encoded proteins. This paper describes expansion of the synthetic scope of 1, the difficulties encountered in this process, particularly issues with epimerization and slow coupling rates, and methods to overcome them. Finally, spectroscopic and physicochemical properties as well as proteolytic stabilities of molecules in this series were measured; these data highlight the suitability of oligo-pyrrolinone-pyrrolidines for the development of pharmacological probes or pharmaceutical leads.
Holistic Privacy for Electricity, Water, and Natural Gas Metering in Next Generation Smart Homes (2021)

In smart electricity grids, high time granularity (HTG) power consumption data can be decomposed into individual appliance load signatures via nonintrusive appliance load monitoring techniques to expose appliance usage profiles. Various methods ranging from load shaping to noise addition and data aggregation have been proposed to mitigate this problem. However, with the growing scarcity of natural resources, utilities other than electricity (e.g., water and natural gas) have also begun to be subject to HTG metering, which creates privacy issues similar to that of electricity. Therefore, employing privacy protection countermeasures for only electricity usage is ineffective for appliances that utilize additional/other metered resources. As such, existing privacy countermeasures and metrics need to be reevaluated to address not only electricity, but also any other resource that is metered. Furthermore, a holistic privacy protection approach for all metered resources must be adopted as the information leak from any of the resources has the potential to render the privacy preserving countermeasures for all the other resources futile. This article introduces the privacy preservation problem for multiple HTG metered resources and explores potential solutions for its mitigation.
Dynamic Container-based Resource Management Framework of Spark Ecosystem (2019)

Apache Spark is known for its robustness in processing large-scale datasets in a distributed computing environment. This form of efficiency is highly observing because of the direct use of Random-Access Memory (RAM) in processing its resilient distributed datasets across the ecosystem. Recently, it is observed that, the memory utilization in computing spark jobs is mainly dependent on job containers, which are closely associated to persistent storage media components. Thus, spark jobs processing relevancy is tightly coupled to the type of storage container and in case of any dynamic resource allocation, the job loses its ratio of resource computation in existing container and increases a functional issue of processing large-scale datasets in spark ecosystem. In this paper, we propose dynamic container-based resource management framework, that shifts coupled associations of job profiles to dynamically available resource containers. Also, it relieves static container allocations and presumes them as a fresh piece of resource allocation for new job profile. The experimental evaluation shows that the proposed dynamic framework reduces wastage of resource allocations and increase ecosystem performance than default job profile in spark ecosystem.
The Plasma Levels of Prostanoids and Plasminogen Activator Inhibitor-1 in Primary and Secondary Thrombocytosis (2005)

An elevated platelet count is a common finding in both hospitalized and ambulatory patients. Thrombosis and bleeding complications are more frequently observed in patients with clonal thrombocytosis than secondary thrombocytosis. The aim of this study was to investigate the behaviors of plasminogen activator inhibitor type 1 (PAI-1), the inhibitor of fibrinolysis; and thromboxane A2 and 6-keto-PGF1 alpha, the products of endoperoxides, in 16 patients affected with clonal thrombocytemia as compared with 16 patients with reactive thrombocytosis and 15 normal controls. In the clonal thrombocytemia group, plasma levels of PAI-1 antigen and activity were significantly higher than both reactive thrombocytosis and control group. Plasma levels of 6-keto-PGF1alpha were significantly higher in the clonal thrombocytemia group than the other two groups and also higher in the reactive thrombocytosis group than the control group, which was also significant. This study confirms that arachidonate metabolism is frequently deranged in patients with thrombocytosis and hypofibrinolysis due to increased PAI-1 plasma levels as shown in the clonal thrombocytosis group. This may explain the thrombotic tendency in myeloproliferative disorders.
The role and future potential of fluorinated biomarkers in positron emission tomography (2010)

(18)F PET is a flourishing field with many applications in drug discovery and development, through radiolabelling of drug molecules or use of fluorinated disease biomarkers.
Chemical state tuning of surface Ce species on pristine CeO<sub>2</sub> with 2400% boosting in peroxidase-like activity for glucose detection (2020)

We demonstrate that the Ce reactivity of CeO<sub>2</sub> towards H<sub>2</sub>O<sub>2</sub> is dictated by its local structure and electron density. More than 2400% increase in peroxidase-like activity has been achieved on the (100) surface for glucose detection due to the promoted H<sub>2</sub>O<sub>2</sub> adsorption and subsequent activation by the electron-rich Ce species.
Motor Learning Models (2005)

Abstract Motor learning models are adaptable systems within the central nervous system which are responsible for skilled motor behavior.
New Synthetic Technology for the Synthesis of Hindered α-Diazoketones via Acyl Mesylates (1999)

[formula: see text] A mild and reliable one-pot protocol for the elaboration of sterically demanding carboxylic acids into alpha-diazoketones via acyl mesylates has been developed. Aside from delineating the reaction parameters which render this strategy quite general for hindered carboxylic acids, we have directly proven the existence of the fleeting acyl mesylate group as the reactive species in these reactions and shed light onto the differing mechanisms which are operative in the activation of hindered and simple carboxylic acids with methanesulfonyl chloride.
The first German evidence-based clinical guidelines on borderline personality disorder (2023)

Introduction Though the evidence regarding the psychotherapeutic and drug treatment of borderline personality disorder (BPD) is rapidly accumulating, with more then 120 randomised controlled trial on the clinical treatment being availabe currently, no evidence-based guidelines existed as yet in Germany. This talk will present the first German evidence-based clinical guidelines for BPD. Objectives In this talk the German evidence-based clinical guidelines for borderline personality disorder will be presented, and focuses and important recommendations highlighted. Methods A diverse, multidisciplinary panel, including members with research and clinical expertise in the treatment and care of individuals with BPD as well as representatives of persons with lived experience and their relatives, has developed the first evidence-based German treatment guidelines for BPD. The Australian NHMRC and the British NICE guidelines were used as source guidelines and adapted, based on the findings of updated literature searches. All recommendations were consented in an independently moderated, formalised consensus process. Special attention was paid to the management of financial and non-financial conflicts of interest. Results The guidelines support the early detection and treatment of BPD and recommend that the diagnosis be made in adolescents from the age of twelve years on. Disorder-specific psychotherapies, i.e. structured psychological therapies that are specifically designed for people with BPD, are recommended as the first-line treatment for BPD. If the primary focus is the treatment of self-harm, Dialectical Behaviour Therapy or Mentalisation-Based Treatment are recommended. Drug treatment should only be considered if in crisis psychological interventions do not suffice and should be withdrawn as early as possible. Besides, drug treatment may only have a role if required for the treatment of comorbid psychic disorders. The guidelines also recommend educating significant others of the person concerned about the disorder and including them in the development of crisis plans. It is also recommended to offer support to relatives, especially if they are children or adolescents. Also, the role of individuals with BPD who are parents is considered, and early support to foster parenting skills and attachment relationships is recommended. Conclusions The first evidence-based German guidelines on BPD are now available and will help to ameliorate the health care of persons with a diagnosis of BPD. The publication of an English version is impending. Disclosure of Interest None Declared
Multi-physics modeling of electro-mechanical oscillators: Comparative analysis of Colpitts and Cross-Coupled architectures (2010)

This paper discusses necessity of multi-physics analysis methodology for electro-mechanical oscillators. Electro-mechanical coupling module is introduced to account for power-energy conversion between electro-mechanical resonators and oscillator active-cores. The proposed methodology is successfully applied to the design of low power and low noise integrated crystal oscillators using NXP-Semiconductors advanced BiCMOS QUBIC technology solutions. A phase noise better than −154dBc/Hz at 10KHz with noise supply rejection better than - 65dB is experimentally demonstrated. Comparative analysis of Colpitts and Cross-Coupled oscillator architectures is proposed. Impact of CML and MOS Amplitude-Level-Control (ALC) regulation schemes on phase-noise performances are investigated. Correlations of experimental results with Cadence Spectre simulation results and Berkeley Design Automation solutions show satisfactory agreement, and underline importance of large-signal assumptions together with proper stability analysis.
Room-Temperature Ionic Liquid. A New Medium for Material Production and Analyses under Vacuum Conditions (2010)

A characteristic of negligible vapor pressure that a room temperature ionic liquid (RTIL) possesses enables us to introduce RTILs in the apparatus requiring vacuum conditions for material production and analyses. This combination creates a path toward development of new techniques under vacuum conditions. As for material production, especially metal nanoparticle synthesis, those are magnetron sputtering onto RTILs, plasma reduction in RTILs, physical vapor deposition onto RTILs, and electron beam and γ-ray irradiation to RTILs. Interestingly, the nanoparticles prepared in RTILs without any stabilizing agent do not aggregate in the RTILs. Also, we can introduce RTILs in analytical instruments requiring vacuum conditions such as X-ray photospectroscopy (XPS), matrix-assisted laser desorption/ionization mass spectroscopy (MALDI-MS), scanning electron microscopy (SEM), and transmission electron microscopy (TEM). The fact that the RTIL is not charged under irradiation by quantum beams enables us to establish new analytical techniques. Furthermore, homogeneous conditions that are obtainable by dissolving a substance in a RTIL are quite useful for conducting analyses using the instruments described above, for example, MALDI-MS, with high reproducibility.
ChemInform Abstract: Computer‐Assisted Design of Chiral Boron Enolates: A Novel, Highly Enantioselective Aldol Reaction for Thioacetates and Thiopropionates. (1994)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.