gebhart/patrepeval huggingface dataset:
Why we compete in DARPA's Urban Challenge autonomous robot race (2007)

The robots will have to find their own way, sensing and predicting their whereabouts through automated perception, planning, and control.
Purification and DNA binding properties of the ataxia-telangiectasia gene product ATM (1999)

The human neurodegenerative and cancer predisposition condition ataxia-telangiectasia is characterized at the cellular level by radiosensitivity, chromosomal instability, and impaired induction of ionizing radiation-induced cell cycle checkpoint controls. Recent work has revealed that the gene defective in ataxia-telangiectasia, termed ATM, encodes an approximately 350-kDa polypeptide, ATM, that is a member of the phosphatidylinositol 3-kinase family. We show that ATM binds DNA and exploit this to purify ATM to near homogeneity. Atomic force microscopy reveals that ATM exists in two populations, with sizes consistent with monomeric and tetrameric states. Atomic force microscopy analyses also show that ATM binds preferentially to DNA ends. This property is similar to that displayed by the DNA-dependent protein kinase catalytic subunit, a phosphatidylinositol 3-kinase family member that functions in DNA damage detection in conjunction with the DNA end-binding protein Ku. Furthermore, purified ATM contains a kinase activity that phosphorylates serine-15 of p53 in a DNA-stimulated manner. These results provide a biochemical assay system for ATM, support genetic data indicating distinct roles for DNA-dependent protein kinase and ATM, and suggest how ATM may signal the presence of DNA damage to p53 and other downstream effectors.
Differences in gadolinium retention after repeated injections of macrocyclic MR contrast agents to rats (2017)

2 Technical Efficacy: Stage 5 J. Magn. Reson. Imaging 2018;47:746-752.
Single-Mode Parametric-Down-Conversion States with 50 Photons as a Source for Mesoscopic Quantum Optics (2016)

We generate pulsed, two-mode squeezed states in a single spatiotemporal mode with mean photon numbers up to 20. We directly measure photon-number correlations between the two modes with transition edge sensors up to 80 photons per mode. This corresponds roughly to a state dimensionality of 6400. We achieve detection efficiencies of 64% in the technologically crucial telecom regime and demonstrate the high quality of our measurements by heralded nonclassical distributions up to 50 photons per pulse and calculated correlation functions up to 40th order.
Role and Use of Secondary Metabolites in Fungal Taxonomy (2020)

This chapter shows that secondary metabolites have been valuable, occasionally even indispensable, in classifications that are expected to be unequivocal and stable. Gross separations were originally introduced using paper chromatography or chemical paper tests, but these have not been used recently in chemotaxonomy except in a few simple diagnostic tests. Gas chromatography (GC) has mostly been used for volatile chemical compounds. High-performance liquid chromatography (HPLC) has become the method of choice for most nonvolatile secondary metabolites. HPLC using gradient elution on reversed-phase material allows a good separation of a large range of secondary metabolites with different polarities, and Ultra Violet (UV) and fluorescence detectors can be used to detect small amounts of most compounds with a chromophore. Diode array detection is particularly relevant in connection with HPLC but can also be used with micellar capillary electrophoresis (MCE). Certain secondary metabolites fluoresce strongly and so can be detected in very low amounts with a fluorescence detector.
Development and characterisation of small-scale rotary engines (2007)

This paper describes the development and characterisation of small-scale rotary engines with displacements in the range of 781500 mm for portable applications in the range of 10200 W of power output. Small-scale combustion engines present a number of research challenges including manufacturing tolerances, sealing, thermal management, ignition, combustion efficiency and porting. Four engines have been characterised using a custom test bench and show an increase in performance due to design changes that mitigate the challenges associated with small-scale engines. The volumetric power density has been increased from 11 W/cm in a 348 mm engine operating with a supercharged hydrogen/air mixture to 22 W/cm in a 1500 mm engine operating with naturally aspirated liquid hydrocarbon fuel. The thermal efficiency has also been increased from 0.2 to 4%. Continued improvements in sealing, thermal management, combustion efficiency and friction reduction will allow further increases in engine performance.
Evidence for Intersections of Coupled g-Mode Sets as a Source of High Frequency Oscillations in Sunspot Occurrence (2008)

We show that sunspots tend to appear at longitudes where coupled sets of g-mode oscillations are depositing the most energy. Since the g-mode sets rotate at predictable rates slower than the Sun, the same predictability should eventually apply to the location and strength of sunspots and other solar activity. When fully developed, this model would provide long term safety warnings for astronauts. In this paper, the rotation rates and initial longitudes of eleven g-mode sets are tested against observations. The paper concludes that the time series of sunspot numbers for the last century has oscillatory components with the same frequencies and temporal phases as the eleven g-mode sets.
PC Calculations Using Gaussian for Windows: A Complement to Laboratory Measurements on HCl (1996)

The Gaussian for Windows program is applied to an ab initio calculation for HCl of structural and electronic properties which are often measured experimentally in undergraduate physical chemistry laboratories. Specifically, a detailed display of the effect of basis set size and calculation level on the bond length Re, the vibrational frequency omega(e), the dipole moment mu(e), and the polarizability alpha(e) is presented along with a potential energy surface scan at the HF, MP2, and QCISD(T) levels of theory. The agreement of the calculated values with experiment generally improves with increases in the basis set size, calculation level, and computational time. We have found that the easy access to such calculations on a laboratory PC encourages students to explore further the effects of different orbital choices and calculation levels, and to apply the Gaussian to other laboratory experiments.
Enhanced phosphorescence properties of a Pt-porphyrin derivative fixed on the surface of nano-porous glass (2018)

The room-temperature phosphorescence chromophore, Pt(II) coproporphyrin I (PtCP), was fixed on the surface of a 3D-network of nanoscale pores of porous glass through ion-exchange reaction. The absorption and phosphorescence spectra indicated that PtCP can be loaded while maintaining monomeric dispersion at concentrations well beyond solubility limits of PtCP in solution. The phosphorescence quantum yield of PtCP fixed on the surface was also found to have double the enhancement of solution. The extended lifetime of phosphorescence of PtCP bonded on the surface compared to that in solution clearly indicated that suppression of nonradiative deactivation plays a key role in high quantum yield and long triplet lifetime. This hybridization with nano-porous glass provides opportunities for various potential applications.
Variations of focal regions versus numbers and positions of sources in two-dimensional media (2001)

This paper explores the behaviour of the primary and secondary hot spots in homogeneous and two-dimensional inhomogeneous medium. Circular arrays are considered with a radius of up to five wavelengths. The number of sources and their positions in the array are varied, and the influence of these variations on the primary and secondary hot spots is observed. It is found that the primary hot spot reaches its final shape with the addition of a very small number of sources to the array. An increase in the number of sources results in a reduction of the normalized magnitude of the secondary hot spots, but the size of the normalized primary hot spot remains the same. An upper limit of sources in the array exists after which no further reduction of the secondary hot spots is observed. The finite-difference time-domain method (FDTD) is used to obtain the electric-field distribution in the inhomogeneous medium. A genetic algorithm is then applied to find the optimal positions of the antennae in the array.
The type II and X cellulose-binding domains of Pseudomonas xylanase A potentiate catalytic activity against complex substrates by a common mechanism (1999)

Xylanase A (Pf Xyn10A), in common with several other Pseudomonas fluorescens subsp. cellulosa polysaccharidases, consists of a Type II cellulose-binding domain (CBD), a catalytic domain (Pf Xyn10A(CD)) and an internal domain that exhibits homology to Type X CBDs. The Type X CBD of Pf Xyn10A, expressed as a discrete entity (CBD(X)) or fused to the catalytic domain (Pf Xyn10A'), bound to amorphous and bacterial microcrystalline cellulose with a K(a) of 2.5 x 10(5) M(-1). CBD(X) exhibited no affinity for soluble forms of cellulose or cello-oligosaccharides, suggesting that the domain interacts with multiple cellulose chains in the insoluble forms of the polysaccharide. Pf Xyn10A' was 2-3 times more active against cellulose-hemicellulose complexes than Pf Xyn10A(CD); however, Pf Xyn10A' and Pf Xyn10A(CD) exhibited the same activity against soluble substrates. CBD(X) did not disrupt the structure of plant-cell-wall material or bacterial microcrystalline cellulose, and did not potentiate Pf Xyn10A(CD) when not covalently linked to the enzyme. There was no substantial difference in the affinity of full-length Pf Xyn10A and the enzyme's Type II CBD for cellulose. The activity of Pf Xyn10A against cellulose-hemicellulose complexes was similar to that of Pf Xyn10A', and a derivative of Pf Xyn10A in which the Type II CBD is linked to the Pf Xyn10A(CD) via a serine-rich linker sequence [Bolam, Cireula, McQueen-Mason, Simpson, Williamson, Rixon, Boraston, Hazlewood and Gilbert (1998) Biochem J. 331, 775-781]. These data indicate that CBD(X) is functional in Pf Xyn10A and that no synergy, either in ligand binding or in the potentiation of catalysis, is evident between the Type II and X CBDs of the xylanase.
Analysis of the Cooling Performance on a Showerhead Cooled Blunt Body using the Wall Cooling Effectiveness (2007)

Keywords: Heat Transfer ; Numerical Analyses ; Turbomachinery ; GTT ; LTT Reference LTT-CONF-2007-002 URL: http://www.euroturbo.eu/ Record created on 2007-04-18, modified on 2017-05-10
Advanced Distribution Management System: Implementation, Assessment, and Challenges (2018)

In recent years, massive numbers of distributed energy resources are being installed in distribution feeders at both the utility and customer levels. These integrations are creating bi-directional power flow complexities in all the existing functionalities of distribution management system (DMS) and outage management system (OMS). Therefore, a significant interest is growing among utilities to combine all the DMS and OMS functionalities with distributed energy resources management system. This combined structure is known as advanced distribution management system (ADMS). In this paper, major ADMS functionalities, such as, conservation voltage reduction, fault location, isolation, and service restoration, and demand response are described with existing and aspiring implementation and assessment. Future challenges are also described from the utility perspective.
Entanglement of Bell Mixtures of Two Qubits (2001)

This paper is an appendix to a previous paper: quant-ph/0101123 ``Relaxation Method for Calculating Quantum Entanglement", by Robert Tucci. For certain mixtures of Bell basis states, namely the Werner States, we use the theoretical machinery of our previous paper to derive algebraic formulas for: the pure and mixed minimization entanglements (i.e., E_{pure} and E_{mixed}), their optimal decompositions and their entanglement operators. This complements and corroborates some results that were obtained numerically but not algebraically in our previous paper. Some of the algebraic formulas presented here are new. Others were first derived using a different method by Bennett et al in quant-ph/9604024.
Registration of single quantum dots using cryogenic laser photolithography (2006)

We have registered the position of single InGaAs quantum dots using a cryogenic laser photolithography technique. This is an important advance towards the reproducible fabrication of solid-state cavity quantum electrodynamic devices, a key requirement for commercial exploitation of quantum information processing. The quantum dot positions were registered with an estimated accuracy of 50nm by fabricating metal alignment markers around them. Photoluminescence spectra from quantum dots before and after marker fabrication were identical except for a small redshift (∼1nm), probably introduced during the reactive ion etching.
Enhanced cryogenic on-wafer techniques for accurate In/sub x/Ga/sub 1-x/As HEMT device models (2002)

An accurate on-wafer cryogenic measurement system is presented for empirical millimeter-wave device studies of In/sub x/Ga/sub 1-x/As HEMTs. Multi-line TRL calibrations are performed to provide traceable baseline results for cryogenic S-parameter measurements. This technique is then applied to develop wide frequency band small-signal models for HEMTs with In channel composition varied from 22% to 70%.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
20 μm cutoff heterojunction interfacial work function internal photoemission detectors (2004)

Results are reported on Heterojunction Interfacial Workfunction Internal Photoemission (HEIWIP) detectors designed for operation up to 20 μm. The peak response of 100 mA/W at 12.5 μm with a D* of 2×1011 Jones was observed with a cutoff wavelength of ∼20 μm. The BLIP temperature for the devices was 40 K at 1.5 V bias. While the peak response remained almost constant (∼95 mA/W) up to 40 K, the D* reduced to 5×109 Jones due to the increased dark current. The response increased with doping while the dark current did not change significantly. Hence, higher responsivity and D* can be expected for designs with higher doping. Designs utilizing increased reflection from the bottom contact are suggested to improve the resonant cavity enhancement for optimizing the detectors, which should lead to higher D* and BLIP temperature.
Volume Bragg gratings as ultra-narrow and multiband optical filters (2012)

High efficiency volume Bragg gratings (VBGs) in photo-thermo-refractive (PTR) glass provide unmatched optical filtering capabilities with optical densities as high as 50 dB and linewidths as narrow as 1 cm<sup>-1</sup>. In this work we review recent advances in VBG technologies that enabled key improvements of high efficiency grating properties and led to development of unique VBG based optical filters for Raman spectroscopy and other applications. Such narrow band notch and bandpass filters make ultra-low frequency Raman measurements possible with single stage spectrometers, therefore, largely improving optical throughput of high end Raman instruments while reducing complexity of the measurements. In this work we also present novel volume multiplexed ultra-narrow band VBG filters with high reflection at multiple wavelengths. Such multiband holographic optical elements are formed by overlapping of several high efficiency VBGs in a single glass plate. Raman spectra obtained with multiband VBG filters and single stage spectrometers, show unmatched capability of the filters to provide simultaneous access to Stokes and anti-Stokes Raman modes with frequencies as low as 5 cm<sup>-1</sup> at different wavelengths.
Patterns of Diastolic Abnormalities during Isometric Stress in Patients with Systemic Hypertension (1997)

This study was undertaken to determine the prevalence and distribution of diastolic function abnormalities at rest and during isometric exercise in patients with systemic hypertension using the recently introduced handgrip-apexcardiographic test (HAT). It has been shown that HAT reflects left ventricular pressure changes in early (relaxation) and late (compliance) diastole. A HAT was obtained in 132 patients with systemic hypertension (duration >1 year) without history of congestive heart failure. A healthy group (n = 186) served as control subjects. Diastolic abnormalities were present at rest in 53/132 (40%) and during isometric handgrip stress in 92/132 (70%) patients. At rest the most frequent diastolic abnormality was the prolongation of relaxation time (27%) whereas an isolated increase in A wave was rare (8%). During isometric exercise, however, an elevation of A wave was the predominant abnormality (38%) whereas an isolated prolongation of relaxation time was less frequent (14%). Alternatively, an 'ischemic' pattern (abnormal prolongation of resting normal relaxation time during handgrip and/or abnormal as well as more than double increase of resting normal relative A wave to total height during or after handgrip) was observed in 29%. In 89% of these patients with an ischemic pattern of diastolic changes, a typical angina and/or positive stress ECG and/or angiographically proved coronary artery disease were present. Using HAT data the present study demonstrates for the first time that in patients with systemic hypertension: (1) diastolic abnormalities occur significantly more frequently during isometric stress than at rest, (2) the most frequently observed diastolic abnormality at rest is the relaxation time prolongation whereas during isometric stress the A wave elevation, and (3) patients with an ischemic pattern of exercise-induced diastolic abnormalities show frequently clinical or angiographic evidence of demand ischemia. Thus, HAT can become a useful additional diagnostic tool for detecting latent diastolic dysfunction and myocardial ischemia in this clinical setting.
Mechanisms of Insulin-Induced Insulin-Receptor Downregulation: Decrease of Receptor Biosynthesis and mRNA Levels (1989)

The influence of insulin on the downregulation of its receptor was studied in AR42J cultured pancreatic acinar cells, a cell line that has been demonstrated to be metabolically responsive to insulin. Downregulation induced by insulin was time and dose dependent. After a 20-h incubation with 1 microM insulin, Scatchard analysis revealed approximately 80% loss of insulin receptors. Studies of receptor half-life indicated that treatment with insulin accelerated the degradation of both the alpha- and beta-subunits of the insulin receptor by 30-60%. In addition, biosynthetic-labeling studies indicated that insulin inhibited the biosynthesis of the insulin-receptor precursor by greater than 30%. This decreased biosynthesis of the precursor was associated with decreased production of mature receptor subunits. Poly(A)+ RNA was extracted from control cells and cells treated for 24 h with 100 nM insulin. Slot blots and Northern transfers revealed that insulin induced an approximately 50% decrease in insulin-receptor mRNA levels. Therefore, these studies indicate that insulin may diminish the concentration of its receptors in target cells by at least two mechanisms: acceleration of receptor degradation and inhibition of receptor biosynthesis at the level of mRNA.
High-Pressure Synthesis, Crystal Structure, And Properties Of δ-Ce(Bo<sub>2</sub>)<sub>3</sub> (2007)

The cerium meta-oxoborate δ -Ce(BO 2 ) 3 was synthesized under high-pressure / high-temperature conditions of 3.5 GPa and 1050 ° C in a Walker-type multianvil apparatus. The crystal structure was determined by single crystal X-ray diffraction data, collected at r. t. The compound crystallizes monoclinicly in the space group P2 1 /c with the lattice parameters a = 422.52(8), b = 1169.7(2), c = 725.2(2) pm, and β = 91.33(3)°. The structure is isotypic to the recently published high-pressure phase δ -La(BO 2 ) 3 , consisting exclusively of corner sharing [BO 4 ] 5− tetrahedra
Genetic organization of sulphur‐controlled aryl desulphonation in <i>Pseudomonas putida</i> S‐313 (1999)

Pseudomonas putida S-313 is able to desulphonate a broad range of aromatic sulphonates to provide sulphur for growth by monooxygenolytic cleavage to yield the corresponding phenol. After miniTn5 transposon mutagenesis of this strain, 11 mutants were isolated that were no longer able to utilize benzenesulphonate as a sulphur source. Three of these mutants were defective in the utilization of all aromatic sulphonates tested, but they grew normally with other sulphur sources. These strains contained independent insertions in the novel 4.2 kb asfRABC gene cluster, encoding a putative reductase (AsfA), a ferredoxin (AsfB), a putative periplasmic binding protein (AsfC), which was localized to the periplasm using alkaline phosphatase fusions, and a divergently oriented fourth gene, asfR, that encoded a LysR-type regulator protein. A further mutant was interrupted in the ssu locus, which includes the gene for a putative desulphonative monooxygenase. Transformation of Pseudomonas aeruginosa with the asfRAB genes was sufficient to allow arylsulphonate utilization by this species, which does not normally use these compounds, suggesting that the AsfAB proteins may constitute an arylsulphonate-specific electron transport system that interacts with a less specific oxygenase. Expression of the asfABC genes in P. putida was induced by benzenesulphonate or toluenesulphonate, and it was repressed in the presence of sulphate in the growth medium. AsfR was a negative regulator of asfABC expression, and toluenesulphonate induced expression of these genes indirectly by reducing the expression of the asfR gene.
Políticas de inclusão social na Unesp 1997-2010: conquistas e desafios (2014)

O objetivo foi investigar se as políticas de inclusão social da UNESP têm possibilitado a conquista efetiva de acesso à universidade pública por jovens formados em escolas públicas e pertencentes a famílias de nível sócio-econômico-cultural tradicionalmente excluído da educação superior, no período de 1997 a 2010. A metodologia envolveu análise documental, análise e tratamento estatístico e análise crítica. Análises da série histórica indicam: avanços na democratização do acesso quanto à condição sócio-econômica, com 72% em 2010 com renda familiar até 10 salários-mínimos; ocupação de aproximadamente 43% das vagas por jovens com formação total ou parcial em escola pública de ensino médio; avanços na equidade de acesso à universidade pública para os que frequentaram cursinhos preparatórios e a persistência do capital cultural como um desafio para a superação das desigualdades de acesso à educação superior.
Synthesis, structure-activity relationships of some aromatic oxybutynyl amine derivatives (2014)

Twelve aromatic oxybutynyl amine derivatives (1 – 12) were synthesized via Mannich reaction. All synthesized compounds were tested for their antimalarial, antibacterial and antifungal activities. Compounds 1, 6 and 7 showed antimalarial activity against chloroquine-sensitive (D6) Plasmodium falciparum protozoan with an IC50 value of 0.65, 1.64 and 2.98 µg/mL and against chloroquine-resistant (W2) Plasmodium falciparum protozoan with an IC50 value of 0.25, 0.77 and 1.13 µg/mL respectively. Compounds 1 and 3 showed antimicrobial activity against Cryptococcus neoformans with an IC50 value of 0.95 and 2.41 µg/mL, against Staphylococcus aureus with an IC50 value of 1.03 and 1.08 µg/mL, against Methicillin-resistant Staphylococcus aureus with an IC50 value of 1.16 and 0.86 µg/mL and against Mycobacterium intracellulare with an IC50 value of < 0.8 and 2.19 µg/mL respectively.