gebhart/patrepeval huggingface dataset:
lntegrated Optical Fiber Sensors in Additive Manufactured Metal Components for Smart Manufacturing Applications (2019)

This work combines fiber optic sensors with additive manufacturing to enable integration of temperature and strain sensors in metal components. In this paper, we present a fiber optic sensor network integrated in press hardening tools to monitor the contact between the tool and the metal sheet during forming operation. The tools are manufactured through metal powder bed fusion using laser melting processes (PBF-SLM), after which the tools are prepared for sensor integration. A demonstrator press hardening tool with integrated fiber optic sensors was heated using an electric heat foil and the sensor measurements was compared to a thermal simulation model. The sensor technology is based on Fiber Bragg Gratings (FBGs), integrated at several positions along the optical fiber. FBGs are in-fiber sensors that are multiplexed. lt is possible to place hundreds of FBG sensors along one single fiber, thus allowing for quasidistributed sensing of temperature or strain. The optical fiber itself can be less than 100 micrometer in diameter, allowing for sensing at several points in a minimally invasive way, when integrated in a tool or component.
Broadband Mid-Infrared Dual Comb Spectroscopy with Comb-Tooth Resolution and High Signal-To-Noise Ratio (2017)

We demonstrate a mid-infrared dual-comb spectrometer that can measure comb-tooth resolved spectra across an octave of bandwidth in the mid-infrared from 2.6—5.2 µm with kHz frequency precision and a signal-to-noise ratio up to 5,000:1.
Efficacité et sécurité du Lumasiran chez les patients atteints d’hyperoxalurie primaire de type 1 : analyse à 24 mois de l’essai ILLUMINATE-A (2022)

Nous rapportons les données de l’analyse à 24 mois (M) d’ILLUMINATE-A. Un essai de phase 3 du lumasiran, un ARNi thérapeutique visant à réduire l’excrétion urinaire d’oxalate (UOx) chez les patients atteints d’hyperoxalurie primaire de type 1 (HP1). ILLUMINATE-A est un essai de phase 3, randomisé, contrôlé par placebo, en cours chez des patients ≥ 6 ans présentant une HP1 génétiquement confirmée et un DFGe ≥ 30 mL/min/1,73 m2, avec une période d’analyse primaire de 6 M suivie d’une période d’extension allant jusqu’à 54 M où tous les patients reçoivent du lumasiran. Sur les 39 patients inclus, 24/26 dans le groupe lumasiran/lumasiran (L/L) et 13/13 dans le groupe placebo/lumasiran (P/L) sont entrés dans la période d’extension. La réduction moyenne de l’UOx sur 24 h à M24 par rapport à l’inclusion était de 58 % dans le groupe L/L et de 49 % dans le groupe P/L. La proportion de patients atteignant une excrétion d’UOx sur 24 h ≤ 1,5x la limite supérieure de la normale à M24 était de 83 % dans le groupe L/L et de 62 % dans le groupe P/L ; les réductions moyennes, par rapport à l’inclusion, de l’oxalate plasmatique à M24 étaient de 56 % et 61 %, respectivement. Le DFGe est resté sTableau dans les deux groupes. Les taux de calculs rénaux ont diminué de 3,19/personne-année au cours des 12 mois précédant le consentement à 0,80 dans le groupe L/L et de 0,54/personne-année à 0,28 dans le groupe P/L. Les effets indésirables les plus fréquents liés au lumasiran étaient des réactions légères et transitoires au site d’injection. Le traitement à long terme par lumasiran a entraîné une réduction soutenue de l’UOx jusqu’à M24 avec une sécurité accepTableau chez les patients atteints de HP1 et des résultats cliniques encourageants.
Optimising non‐viral gene delivery in a tumour spheroid model (2006)

This data provides new insights into tumour-specific factors affecting non-viral gene transfer and highlights the difficulties in delivering genes to avascular tumour regions. The MCTS model is a useful system for the initial screening of future gene therapy strategies for solid tumours.
Association of prone position with sudden unexpected death in epilepsy (2015)

There is a significant association between prone position and SUDEP, which suggests that prone position is a major risk factor for SUDEP, particularly in patients aged 40 years and younger. As such, SUDEP may share mechanisms similar to sudden infant death syndrome.
Processor scheduling and allocation for 3D torus multicomputer systems (2000)

Multicomputer systems achieve high performance by utilizing a number of computing nodes. Recently, by achieving significant reductions in communication delay, the three-dimensional (3D) torus has emerged as a new candidate interconnection topology for message-passing multicomputer systems. In this paper, we propose an efficient processor allocation scheme-scan search scheme-for the 3D torus based on a first-fit approach. The scan search scheme minimizes the average allocation time for an incoming task by effectively manipulating the 3D information on a torus as 2D information using a data structure called the CST (Coverage Status Table). Comprehensive computer simulation reveals that the allocation time of the scan search scheme is always smaller than that of the earlier scheme based on a best-fit approach. The difference gets larger as the input load increases, and it is as much a factor of 3 for high load. To investigate the performance of the proposed scheme in different scheduling environments, we also consider a non-FCFS scheduling policy along with the typical FCFS policy. The allocation time complexity of the scan search scheme is O(LW/sup 2/H/sup 2/). This is significantly smaller than that of the existing scheme which is O(L/sup 4/W/sup 4/H/sup 4/). Here, L, W, and H represent the length, width, and height of 3D torus, respectively.
Optical Imaging of Paramagnetic Bead-DNA Aggregation Inhibition Allows for Low Copy Number Detection of Infectious Pathogens (2015)

DNA-paramagnetic silica bead aggregation in a rotating magnetic field facilitates the quantification of DNA with femtogram sensitivity, but yields no sequence-specific information. Here we provide an original description of aggregation inhibition for the detection of DNA and RNA in a sequence-specific manner following loop-mediated isothermal amplification (LAMP). The fragments generated via LAMP fail to induce chaotrope-mediated bead aggregation; however, due to their ability to passivate the bead surface, they effectively inhibit bead aggregation by longer 'trigger' DNA. We demonstrate the utility of aggregation inhibition as a method for the detection of bacterial and viral pathogens with sensitivity that approaches single copies of the target. We successfully use this methodology for the detection of notable food-borne pathogens Escherichia coli O157:H7 and Salmonella enterica, as well as Rift Valley fever virus, a weaponizable virus of national security concern. We also show the concentration dependence of aggregation inhibition, suggesting the potential for quantification of target nucleic acid in clinical and environmental samples. Lastly, we demonstrate the ability to rapidly detect infectious pathogens by utilizing a cell phone and custom-written application (App), making this novel detection modality fully portable for point-of-care use.
Opening the networks with Parlay/OSA standards and aspects behind the APIs (2003)

Recently there has been an enormous increase in efforts to open up telecommunication networks for application development. In opening up the network, new business models emerge where applications can be developed and provided by enterprises outside the traditional network operator domain. This new business model, combined with the fact that applications can be built using standardized API with off-the-shelf IT technology and tools, will result in new innovative applications that will hit the market with drastically reduced development cycles. This article provides an overview of the Parlay/OSA initiatives concerning the specification of a set of open standardized API. Furthermore, the article outlines some architectural aspects that are implied and implicitly contained in the Parlay/OSA specifications. These are critical for understanding the implications when allowing access to the network via Parlay/OSA. The article then outlines different types of applications that can be built using Parlay/OSA. Finally, we conclude with an analysis of the future of Parlay/OSA.
Conformation of thymosin β9 in water/fluoroalcohol solution determined by NMR spectroscopy (1997)

The conformation of thymosin beta 9 in solution of 40% (v/v) 1,1,1,3,3,3-hexafluoro-2-propanol-d2 in water has been investigated by two-dimensional 1H-nmr spectroscopy. Under this condition thymosin beta 9 adopts an ordered structure. The determination of the conformation of the peptide was based on a set of 304 approximate interproton distance constraints derived from nuclear Overhauser enhancement measurements. The conformation of thymosin beta 9 includes two helical regions from residues 4 to 27 and 32 to 41. The two helices are separated by a poorly defined loop region between amino acids 28 and 31; the N-terminus of thymosin beta 9 shows random-coil structure only.
ChemInform Abstract: A Novel Sb<sub>2</sub>Te<sub>3</sub> Polymorph Stable at the Nanoscale. (2015)

Abstract Self‐assembled Sb 2 Te 3 nanowires with diameters of &lt;40 nm are grown on a Si wafer coated with a 50 nm SiO 2 layer in a thermal MOCVD reactor using (Me 2 N) 3 Sb and iPr 2 Te as precursors in the presence of (Me 2 N) 4 Ge.
Depolarizing trihedral corner reflectors for radar navigation and remote sensing (1995)

A conventional trihedral corner reflector can be modified to present either a twist-polarizing or a circularly polarizing response by adding conducting fins of rectangular corrugations of prescribed dimensions and orientation to one of its interior surfaces. Since the modified reflector retains most of the mechanical ruggedness and ease of manufacture of the original, it is suitable for deployment in the field for extended periods as required in radar navigation and remote sensing applications. For most directions of incidence the response of the reflector is dominated by triple-bounce reflections from the interior and is a function of the size and shape of the reflecting panels, the dimensions of the corrugations, and the orientation of the reflector with respect to the radar. Experimental results show that prototype twist-polarizing and circularly polarizing reflectors respond as predicted.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Two Novel Class II Hydrophobins from Trichoderma spp. Stimulate Enzymatic Hydrolysis of Poly(Ethylene Terephthalate) when Expressed as Fusion Proteins (2013)

Poly(ethylene terephthalate) (PET) can be functionalized and/or recycled via hydrolysis by microbial cutinases. The rate of hydrolysis is however low. Here, we tested whether hydrophobins (HFBs), small secreted fungal proteins containing eight positionally conserved cysteine residues, are able to enhance the rate of enzymatic hydrolysis of PET. Species of the fungal genus Trichoderma have the most proliferated arsenal of class II hydrophobin-encoding genes among fungi. To this end, we studied two novel class II HFBs (HFB4 and HFB7) of Trichoderma. HFB4 and HFB7, produced in Escherichia coli as fusions to the C terminus of glutathione S-transferase, exhibited subtle structural differences reflected in hydrophobicity plots that correlated with unequal hydrophobicity and hydrophily, respectively, of particular amino acid residues. Both proteins exhibited a dosage-dependent stimulation effect on PET hydrolysis by cutinase from Humicola insolens, with HFB4 displaying an adsorption isotherm-like behavior, whereas HFB7 was active only at very low concentrations and was inhibitory at higher concentrations. We conclude that class II HFBs can stimulate the activity of cutinases on PET, but individual HFBs can display different properties. The present findings suggest that hydrophobins can be used in the enzymatic hydrolysis of aromatic-aliphatic polyesters such as PET.
Redefining ‘success’: a systematic review and meta-analysis comparing outcomes between incomplete and complete revascularization (2018)

Differences in all major outcome measures were markedly better in patients with complete versus incomplete but still 'successful' revascularization using prior thresholds, with ORs in the order of those seen in recent definitive trials comparing EVT to an intravenous tissue plasminogen activator.
Ventricular Rate During Atrial Fibrillation Before and After Slow-Pathway Ablation (1996)

Slow-pathway ablation slows the ventricular rate during atrial fibrillation under conditions of autonomic blockade but not during sympathetic stimulation. Therefore, slow-pathway ablation alone cannot account for the clinical results obtained with radiofrequency modification of AV conduction in patients with atrial fibrillation.
KrF excimer laser lithography technology for 64M DRAM. (1991)

New KrF excimer laser resist was developed. The chemically amplified positive resist, named ASKA, attained high sensitivity (3OmJ/cm2), high resolution (0.3 micron) and high stability. This resist was successfully applied to the fabrication of 64M DRAM with KrF excimer laser stepper (N.A 0.42). This paper describes the chemistry and lithographic characteristics of ASKA, followed by the demonstration of actual pattern fabrication of 64M DRAM.
Characterization of Oxide Films on SiC by Spectroscopic Ellipsometry (2000)

We have, for the first time, evaluated the optical constants of thermally oxidized films on SiC by spectroscopic ellipsometry, and discussed the characteristics of SiC/SiO 2 interfaces. It was found that the effective refractive indices are smaller than those of the oxide films on Si. They increase with oxidation time, or oxide thickness, reaching to the values of Si oxides. The refractive indices also depend on the oxidation methods, and the pyrogenic oxidation brings about larger refractive indices than dry oxidation. The origin of the small refractive indices of oxide films on SiC was discussed in terms of interface structures and composition in comparison with those of oxide films on Si.
Nanoscale Energy Transport in Information Technology Research With an Application to High-Density Data Storage Devices and Systems (2002)

By all measures, the data storage industry is one of the most important components of the Information Technology (IT) revolution. In recent years, many of the emerging technologies rely heavily on energy transport at extremely short time and length scales as a mean to overcome the superparamagnetic limit - a serious impediment to future advancement of storage technology. Additionally, thermally induced failure and reliability issues at the nanoscale are becoming increasingly important due to rapid device miniaturization in data storage applications. Further advances in high-technology data storage systems will be difficult, if not impossible, without rigorous treatment of nanoscale energy transport. This manuscript reviews the thermal design issues and challenges in thermally assisted magnetic disk recording, thermally assisted scanned probe recording, phase change optical data recording, magnetoresistive random access memory (MRAM) and giant magnetoresistive (GMR) heads. Relevant thermally induced failures in GMR heads, write coil, interconnects and MRAM will be discussed as well.
ChemInform Abstract: The Reaction of Quaternary Ammonium Salts Derived from 2‐Aryl‐3‐(N,N‐dimethylamino)‐1‐propenes with Oxygen‐Containing Nucleophiles. (1990)

Abstract The known quaternary ammonium salts (I), derived from 2‐aryl‐3‐aminopropenes, are treated with sodium alkoxides, generated from the alcohols (II), to produce the 2‐arylallyl ethers (III).
Impact of different post-remission strategies on quality of life in patients with acute myeloid leukemia (2008)

These results indicate that, compared to conventional chemotherapy, allogeneic stem cell transplantation has a significantly worse long-term impact on quality of life. This needs to be considered when treatment options are discussed.
Prostate Cancer Specificity of PCA3 Gene Testing: Examples from Clinical Practice. (2008)

A specific marker for early prostate cancer would fill an important void. In initial evaluations of the prostate cancer antigen 3 (PCA3) gene vis-à-vis serum prostate-specific antigen (PSA) levels, the gene offers great promise. At the cellular level, PCA3 specificity for cancer is nearly perfect because of the gross overexpression of the gene by cancer cells. As a clinical test for early prostate cancer, heightened specificity is also seen in urine containing prostate cells from men with the disease. PCA3 gene testing holds valuable potential in PSA quandary situations: (1) men with elevated PSA levels but no cancer on initial biopsy; (2) men found to have cancer despite normal levels of PSA; (3) men with PSA elevations associated with varying degrees of prostatitis; and (4) men undergoing active surveillance for presumed microfocal disease.
On using coherence to measure distortion in hearing aids (1992)

Coherence is a frequency-domain measure of the degree to which the output of a system is linearly related to the system input. The signal-to-distortion ratio (SDR), where the distortion term includes all nonlinear effects and noise in the system, can be computed from the coherence. The coherence estimate, however, is subject to sources of variance and bias that reduce the accuracy of the measured SDR. The origins of the variance and bias and their effects on distortion measurements are presented. New procedures for reducing the variance and bias effects are described, and the processing effectiveness is demonstrated for a simulated hearing-aid response.
Provisioning behavior of male and female Loggerhead Shrikes (2022)

The unique predatory, caching, and impaling behaviors of shrikes (Laniidae) may provide these unusual passerines with alternative provisioning strategies compared to other songbirds, but few studies have determined the impact these unique behaviors have on provisioning rates. Our objectives were to compare the provisioning behavior of male and female Loggerhead Shrikes ( Lanius ludovicianus), and determine how their provisioning behavior was influenced by nestling age. The provisioning behavior of six pairs of Loggerhead Shrikes was videotaped from 15 April to 15 August 2004–2007 in Garrard and Madison counties, Kentucky, USA. For each nest visit by a shrike, the sex of the visiting adult, number of prey items delivered, size of prey, type of prey, and the duration of the nest visit were recorded. Adults made 2169 visits to nests, with males (49%) and females (51%) making similar numbers of visits. Males and females differed in time spent at nests, with males spending less time at nests per visit (mean = 12.0 s, N = 1062) than females (77.0 s, N = 1107). Feeding rates did not differ between the sexes, but feeding rates did increase with nestling age. The size of prey delivered to nestlings also tended to increase with nestling age. Invertebrates comprised 65% of the identified prey items, and cached items made up the remaining 35%. Although many passerine species increase provisioning rates as nestling demand increases, the caching behavior of shrikes may allow adults to reliably increase both feeding rates and prey size as nestling age and demand increase as well as act as buffers when prey availability declines. The caching behavior of shrikes provides them with parental provisioning strategies not available to non-caching songbirds.
Non-linear chalcogenide glasses and technologies for the development of ultra-fast chip-scale optical devices (2008)

Chalcogenide glasses are novel highly non-linear materials for photonics. Modification of optical glasses by high-intensity femtosecond pulses is a novel fast developing technology based on non-linear effects. In this paper, the advantages of using the method of femtosecond modifications for the fabrication of highly non-linear 3D photonic structures in bulk chalcogenide glasses are overviewed. Design and modelling of chip-scale highly non-linear structures for all-optical signal processing are discussed.
Search for new physics in events with opposite-sign leptons, jets, and missing transverse energy in pp collisions at √s = 7 TeV (2012)

A search is presented for physics beyond the standard model (BSM) in final states with a pair of opposite-sign isolated leptons accompanied by jets and missing trans- verse energy. The search uses LHC data recorded at a center-of-mass energy √s = 7 TeV with the CMS detector, corresponding to an integrated luminosity of approxi- mately 5 fb−1. Two complementary search strategies are employed. The first probes models with a specific dilepton production mechanism that leads to a characteristic kinematic edge in the dilepton mass distribution. The second strategy probes models of dilepton production with heavy, colored objects that decay to final states includ- ing invisible particles, leading to very large hadronic activity and missing transverse energy. No evidence for an event yield in excess of the standard model expectations is found. Upper limits on the BSM contributions to the signal regions are deduced from the results, which are used to exclude a region of the parameter space of the constrained minimal supersymmetric extension of the standard model. Additional information related to detector efficiencies and response is provided to allow testing specific models of BSM physics not considered in this paper.
Dataset of fire tests with lithium-ion battery electric vehicles in road tunnels (2022)

A set of five fire tests involving battery electric vehicles and conventional cars was performed in a tunnel. This data article provides the dataset of some of the determined parameters: air temperature, air velocity and heat release rate. The air temperature was measured at several locations and at different heights, distributed in the cross section of the tunnel. The velocity of the incoming air was also measured. The third parameter, the heat release rate (HRR), was calculated based on the enthalpy flow before and after the fire location. This parameter is important for characterizing the size of a vehicle fire. The data provide a reference for the evaluation of BEV fires and could be taken as reference for further fire studies. They might be also of interest to research groups dealing with simulation applications, like three-dimensional CFD simulations.
Securing IoT using layer characterstics (2017)

IoT has gained significant popularity and securing such mission critical network remains a big concern. There are already reports of misusing such system. Recently there were reports of sending spam from a refrigerator. Bigger risk of security in IoT is that unrelated systems are connected and if any attacker gets into one object, it could result in harming much bigger segment. Also such connected networks will really be disconnected in terms of management and applied policies. So applying secured policy at each network segment will only help at certain level but it would not be feasible to secure whole ecosystem of IoT devices/objects. Security has been identified as one of the biggest challenge in IoT segment and there are no solid specs or techniques to come over these issue end to end. This paper outlines use of machine learning combining with interesting dimensions like layer characteristics of IoT device's network stack. Paper also provides example of layer characteristics, which are specific to a device, and creating a baseline of such characteristics using machine learning algorithm will help in establishing the identity of IoT devices without the need of sophisticated PKI infrastructure.