gebhart/patrepeval huggingface dataset:
Composição de ácidos graxos do queijo e leite de vacas alimentadas com casca de banana (2018)

RESUMO Objetivou-se avaliar os níveis de casca de banana seca ao sol na dieta de vacas F1 Holandês x Zebu sobre o perfil de ácidos graxos do leite e do queijo minas frescal. Os tratamentos foram constituídos de 0, 15, 30, 45 e 60% de substituição da silagem de sorgo pela casca de banana. O delineamento experimental foi em dois quadrados latinos 5 x 5 simultâneos. As amostras de leite e queijo foram analisadas quanto ao perfil de ácidos graxos por cromatografia gasosa. Observou-se efeito quadrático para o somatório de ácidos graxos poli-insaturados do leite, com valor máximo no nível de 23,54% de substituição. Houve efeito linear decrescente para os ácidos graxos C15:0 iso e C16:0 iso. Os ácidos graxos heneicosanoico, linoleico, linoleico conjugado e araquidônico apresentaram efeito quadrático. Não houve efeito das dietas sobre os ácidos graxos no queijo. A substituição de até 60% da silagem de sorgo por casca de banana na dieta de vacas em lactação pode ser alternativa para produção e processamento do leite, quando se considera a melhora no valor nutricional da fração lipídica do leite e o aumento dos teores de ácido linoleico conjugado.
3.2 A Chopper-Stabilized Amplifier with a Relaxed Fill-In Technique and 22.6pA Input Current (2023)

In chopper amplifiers, the interaction between the input signal and the chopper clock can cause intermodulation distortion (IMD). This is due to amplifier delay, which causes signal transitions generated by the input chopper to arrive at the amplifier's output slightly later than the corresponding clock transitions of the output chopper. This causes large signal-dependent spikes in the final output, which can significantly degrade amplifier linearity, especially at input frequencies near even multiples of the chopping frequency F <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">cH</inf> , which will cause IMD tones near DC. In [2–4], spread-spectrum clocks are used to convert such tones into noise-like signals. However, this increases the noise floor, without solving the underlying problem. Recently, it has been shown that such spikes can be eliminated by using the fill-in technique [1], in which two identical OTAs are chopped in quadrature, allowing a spike-free output to be generated by switching between their outputs in a ping-pong fashion.
Bit level processor arrays: current architectures and a design and programming tool (2003)

The authors review bit-level processor arrays and the common characteristics that make them ideal for VLSI and high-speed computations. Emphasis is on arrays that have been implemented rather than proposed architectures. The essential features shared by these arrays, and those that differentiate them are characterized and used to develop a taxonomy for bit-level processor arrays. The authors also discuss programming tools, with an emphasis on RAB, a large program used to map a class of algorithms written in C onto bit-level processor arrays. The basic components and extensions to RAB are discussed. Directions of current research and design of bit-level processor array architectures and their programming environments are also briefly discussed.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Determination of the mechanism of retrotransfer by mechanistic mathematical modeling (1992)

Two mathematical models to elucidate the mechanism of retromobilization (or retrotransfer), that is, the ability of conjugative plasmids to mobilize genes into the cell containing the conjugative plasmid, were developed. This study deals with retromobilization of nonconjugative plasmids (Tra-Mob+). Plasmid transfer was modeled by two mass action models. The first is based on the hypothesis that retromobilization of the Tra-Mob+ vector occurs in one step, by means of the pilus formed by the Tra+ plasmid in the original host. In the second model, retromobilization is considered to be a two-step process involving two transfer events. The first step involves the transfer of the Tra+ plasmid from the recipient cell to the donor of the nonconjugative vector, and during the second encounter the nonconjugative vector is mobilized toward the recipient. Since the relationships between the number of transconjugants and the number of recipients for the two models are different, filter matings were performed for short time periods with different initial densities of the recipient population. Comparison of the numbers of transconjugants with the results of the mathematical equations confirmed the hypothesis that retromobilization is a one-step conjugation process.
Voltage independence control of split-DC bus for a three-phase/level T-type converter with unbalanced loads (2017)

Three-phase/level T-type converter has advantages of high efficiency and low current harmonics, which is utilized in power conversion systems for supplying dc loads widely. Three-phase/level T-type converter provides bipolar dc buses with a neutral line at relatively low cost. In order to extend applications for bipolar dc bus structure, voltage independence control of split-dc bus proposed in this paper plays a key role in the flexibility of converter. However, the coupling relationship between asymmetric capacitor voltages and unbalanced dc loads gives rise to the inherent operational limit of three-level T-type converter. Therefore, the serious grid current distortion and attenuation of neutral point voltage regulation appears when system is driven out of operational limit. To overcome these issues, a novel architecture consisting of a three-phase/level T-type converter and a neutral leg is proposed to deal with asymmetric capacitor voltages with any unbalanced dc loads. Voltage independence control of split-dc bus and modified carrier based pulse width modulation (CBPWM) of novel architecture are presented, correspondingly. The simulation and experimental results are presented to validate the proposed architecture and control strategy.
Living at home with acquired cognitive impairment – Can assistive technology help? (2007)

This paper describes an ongoing project developing an innovative approach to the introduction of assistive technology to the homes of elderly people with acquired cognitive impairment in Sweden. The project is client driven with the key objective bei
Cross-sectional scanning tunneling microscopy of Mn-doped GaAs:  Theory and experiment (2003)

We report first-principles calculations of the energetics and simulated scanning tunneling microscopy (STM) images for Mn dopants near the GaAs (110) surface, and compare the results with cross-sectional STM images. The Mn configurations considered here include substitutionals, interstitials, and complexes of substitutionals and interstitials in the first three layers near the surface. Based on detailed comparisons of the simulated and experimental images, we identify three types of Mn configurations imaged at the surface: (1) single Mn substitutionals, (2) pairs of Mn substitutionals, and (3) complexes of Mn substitutionals and interstitials.
Search for antifungal and anticancer compounds from native plant species of Cerrado and Atlantic Forest. (1999)

Bioactivity-guided fractionation of several bioactive extracts obtained from Cerrado and Atlantic Forest plant species led to the isolation of potent DNA-damaging piperidine 1-5 and guanidine alkaloids 6-9 from Cassia leptophylla and Pterogyne nitens respectively, two common Leguminosae from Atlantic Forest. By means of biotechnological approach on Maytenus aquifolium, a species from Cerrado, moderate DNA-damaging sesquiterpene pyridine alkaloid 10-11 was isolated. Bioassay-guided fractionation on Casearia sylvestris, a medicinal plant species found in Cerrado and Atlantic Forest, led to the isolation of clerodane diterpenes 12-13 which showed effect on DNA. In addition, we have reported several interesting potent antifungal iridoids: 1 beta-hydroxy-dihydrocornin (14), 1 alpha-hydroxy-dihydrocornin (15), alpha-gardiol (16), beta-gardiol (17), plumericin (18), isoplumericin (19), 11-O-trans-caffeoylteucrein (20); ester derivative: 2-methyl-4-hydroxy-butyl-caffeoate (21), amide N-[7-(3',4'-methylenedioxyphenyl)-2Z, 4Z-heptadienoyl] pyrrolidine (22) and triterpene viburgenin (23).
Morphological and molecular characterization of native isolates of Trichoderma and its potential biocontrol against Phytophthora infestans (2017)

El presente trabajo muestra la caracterización morfológica y molecular de 10 cepas nativas de Trichoderma (TL2, TL4, TL5, TL6, TX7, TX8, TT6, TF8, TF10 y TJ6) y su relación filogenética, así como su capacidad de biocontrol contra Phytophthora infestans. Los resultados de la caracterización molecular al amplificar la región ITS1-ITS4 del ADN ribosómico nuclear y un fragmento del gen tef1α mostraron que de las 10 cepas, seis corresponden a Trichoderma asperellum (TL2, TL4, TX7, TX8, TT6 y TF8) y cuatro a T. harzianum/Hypocrea lixii (TL5, TL6, TF10 y TJ6). El análisis filogenético por máxima parsimonia demostró que existe una estrecha relación entre las cepas de estos dos grupos. Las pruebas in vitro de biocontrol entre el antagonista y el patógeno indicaron diferencias significativas (p&lt;0.05). La cepa TX8 registró el mayor porcentaje (98 %) de inhibición, mientras que TL4 fue la de menor porcentaje (49 %). Las cuatro cepas de H. lixii (TL5, TL6, TF10 y TJ6) presentaron capacidad de inhibición media (55-66 %).
Increased Carrier Prevalence Of Deficient <i>Cyp2C9</i> , <i>Cyp2C19</i> and <i>Cyp2D6</i> Alleles in Depressed Patients Referred to a Tertiary Psychiatric Hospital (2008)

These findings reveal that clinically relevant CYP2C9 polymorphisms occur more frequently in depressed psychiatric patients than in nonpsychiatric controls. The same trend was found for polymorphisms in the CYP2D6 gene. We found a significant cumulative metabolic deficiency in the psychiatric population for combinations of the CYP2C9, CYP2C19 and CYP2D6 genes. The significant enrichment of CYP2C9-deficient alleles in the psychiatric population validates a previously reported association of this gene with the risk for depression disorders. The high prevalence of carriers with deficient and null alleles suggests that CYP450 DNA typing may play a role in the management of psychiatric patients at tertiary care institutions.
SiGe-On-Insulator (SGOI) Technology and MOSFET Fabrication (2002)

In this work, we have developed two different fabrication processes for relaxed Si&#x2081;&#x208B;xGex-on-insulator (SGOI) substrates: (1) SGOI fabrication by etch-back approach, and (2) by "smart-cut" approach utilizing hydrogen implantation. Etch-back approach produces SGOI substrate with less defects in SiGe film, but the SiGe film uniformity is inferior. "Smart-cut" approach has better control on the SiGe film thickness and uniformity, and is applicable to wider Ge content range of the SiGe film. We have also fabricated strained-Si n-MOSFET’s on SGOI substrates, in which epitaxial regrowth was used to produce the surface strained Si layer on relaxed SGOI substrate, followed by large-area n-MOSFET’s fabrication on this structure. The measured electron mobility shows significant enhancement (1.7 times) over both the universal mobility and that of co-processed bulk-Si MOSFET’s. This SGOI process has a low thermal budget and thus is compatible with a wide range of Ge contents in Si&#x2081;&#x208B;xGex layer.
Influence of the Boron Moiety and Water on Suzuki–Miyaura Catalyst‐Transfer Condensation Polymerization (2014)

Although water promotes Suzuki-Miyaura coupling reaction, it also induces side reactions such as deboronation and dehalogenation. Therefore, Suzuki-Miyaura polymerization of triolborate halothiophene monomer 1 with (t) Bu3 PPd(o-tolyl)Br (2) in dry tetrahydrofuran (THF) is investigated. However, the resultant poly(3-hexylthiophene) (P3HT) shows a broad molecular weight distribution and uncontrolled polymer ends. Model reactions of a number of boron reagents 3 with 2,5-dibromothiophene (4) in the presence or absence of water indicate that intramolecular transfer of the catalyst is hardly affected by the boron moiety of 3, whereas it is hindered in the absence of water. Indeed, polymerization of 1 with 2 in H2 O/THF affords P3HT with a narrower molecular weight distribution and controlled tolyl/H ends, as compared to the reaction in dry THF.
Zweiphasentitration von anionischen Tensiden - ein neuer Ansatz / Two phase titration of anionic surfactants - a new approach (1997)

Article Zweiphasentitration von anionischen Tensiden - ein neuer Ansatz / Two phase titration of anionic surfactants - a new approach was published on May 1, 1997 in the journal Tenside Surfactants Detergents (volume 34, issue 3).
Figure S1 from Identification of Membrane-expressed CAPRIN-1 as a Novel and Universal Cancer Target, and Generation of a Therapeutic Anti-CAPRIN-1 Antibody TRK-950 (2023)

&lt;p&gt;Anti-CAPRIN-1 antibodies&lt;/p&gt;
Navier-Stokes Analysis of Unsteady Transonic Flows Through Gas Turbine Cascades With and Without Coolant Ejection (1997)

An implicit time-marching higher-order accurate finite-difference method for solving the two-dimensional compressible Navier-Stokes equations was applied to the numerical analyses of steady and unsteady, subsonic and transonic viscous flows through gas turbine cascades with trailing edge coolant ejection. Annular cascade tests were carried out to verify the accuracy of the present analysis. The unsteady aerodynamic mechanisms associated with the interaction between the trailing edge vortices and shock waves and the effect of coolant ejection were evaluated with the present analysis.
High prevalence of familial defective apolipoprotein B-100 in Switzerland. (1994)

Familial defective apolipoprotein B-100 (FDB) is caused by a single G-to-A substitution at nucleotide 10,708 leading to an arginine to glutamine change at amino acid 3,500 of the apolipoprotein B-100 and thus, a reduced binding of the apolipoprotein B to the low density lipoprotein (LDL) receptor. In the present study, the prevalence of FDB in Switzerland was estimated, on the one hand, from a sample of 728 healthy volunteers whose origin was spread out over the entire German, French, and Romansh speaking parts of the country, and, on the other hand, from 142 unrelated Swiss families with primary hypercholesterolemia comprising 520 individuals. Using polymerase chain reaction (PCR)-based methods, three individuals were identified with the point mutation in the sample of volunteers, equivalent to a prevalence of approximately 1/240 (90% confidence interval: 1.51 x 10(-3)-1.03 x 10(-2)). The frequency of FDB in the sample of hypercholesterolemic subjects was 7/142, yielding a prevalence of approximately 1/190 extrapolated to the general population (90% confidence interval: 2.63 x 10(-3)-9.17 x 10(-2)). The combined prevalence based on both samples was 1/209. Thus, the investigated point mutation was highly prevalent in Switzerland and appeared to be more frequent than in other populations studied hitherto. Furthermore, the presence of the mutation was not necessarily associated with an elevation of serum cholesterol levels, particularly in young individuals. While in the non-affected volunteers cholesterol levels increased between the age of 19 and 23 years by 0.22 mmol/l or by 5.6% (P = 0.001), this phenomenon was even more pronounced in individuals with FDB. The three volunteers with the point mutation demonstrated an increase in total cholesterol concentrations by 1.30 mmol/l or by 25% within 2 years, suggesting that, in the early twenties, cholesterol concentrations increase markedly from normal to elevated levels. Considering the estimated high prevalence and the relative ease of PCR-based tests, screening for FDB may become a standard procedure in patients with suggested familial forms of hypercholesterolemia.
The Role of Chlorine during High Growth Rate Epitaxy (2015)

The influence of chlorine has been investigated for high growth rates of 4H-SiC epilayers on 4o off-cut substrates. Samples were grown at a growth rate of approximately 50 and 100 μm/h and various Cl/Si ratios. The growth rate, net doping concentration and charge carrier lifetime have been studied as a function of Cl/Si ratio. This study shows some indications that a high Cl concentration in the growth cell leads to less availability of Si during the growth process.
Business metro Ethernet services over DOCSIS&amp;#x00AE; 3.1 (2015)

DOCSIS® 3.1 systems were designed to achieve high capacities with predictable Quality of Service (QoS) promising 2 Gbps on the upstream and 10 Gbps on the downstream. This paper describes L2VPN business services over DOCSIS® 3.1, extension of MPLS to customer premise, virtualization of Customer Premises Equipment (CPE) and interaction of the L2VPN application with SDN controller to support business services.
A Soft-Matter Biomolecular Memristor Synapse for Neuromorphic Systems (2018)

The goal of neuromorphic computing is to recreate the computational power and efficiency of the human brain with circuitry. The ability of the brain to solve complex real time tasks, while consuming 20 W of power on average, is made possible through its connection density, adaptability, and parallel processing. Recreating these features using traditional electronics circuit elements is incredibly difficult, and therefore, soft-matter memristors made of biomolecules similar to those found in biological synapses and capable of emulating various synaptic features can be used as neuromorphic hardware. In this work, we introduce and experimentally demonstrate an electronic neuron circuit capable of interacting with ionic, soft-matter memristors. These memristors are proven to exhibit short-term plasticity, especially paired-pulse facilitation and depression found in presynaptic terminals - features that are not found in state-of-the-art solid-state memristors. We make use of these features for applications in online learning by developing a synapse-neuron circuit which implements spike-rate-dependent plasticity (SRDP) as a learning function.
Frisbee (2021)

With failures being unavoidable, a system's ability to recover from failures quickly is a critical factor in the overall availability of the system. Although many systems exhibit self-healing properties, their behavior in the presence of failures is poorly understood. This is primarily due to the shortcomings of existing benchmarks, which cannot generate failures. For a more accurate systems evaluation, we argue that it is essential to create new suites that treat failures as first-class citizens. We present Frisbee, a benchmark suite and evaluation methodology for comparing the recovery behavior of highly available systems. Frisbee is built for the Kubernetes environment, leveraging several valuable tools in its stack, including Chaos tools for fault injection, Prometheus for distributed monitoring, and Grafana for visualization. We discuss a set of design requirements and present an initial prototype that makes faultloads as easy to run and characterize as traditional performance workloads. Furthermore, we define a core set of failure patterns against which systems can be compared.
Abstract 19426: DMGV is Associated With Cardiometabolic Traits and Predicts Incident Coronary Artery Disease (2017)

Background: We previously identified α-keto-δ-(NGNG-dimethylguanidino)-valeric acid (DMGV) as a novel marker of CT-defined liver fat. DMGV is a poorly characterized transamination product of asymme...
DNA Immunization of HLA Transgenic Mice with a Plasmid Expressing Mycobacterial Heat Shock Protein 65 Results in HLA Class I- and II-Restricted T Cell Responses That Can Be Augmented by Cytokines (2001)

Infection with Mycobacterium tuberculosis (MTB) remains a major cause of morbidity and mortality world-wide. An effective vaccination strategy is the immunization with plasmid DNA (pDNA), expressing an antigen (Ag) from a pathogen in vivo, which results in specific immune response against the encoded protein as well as the pathogen itself or cells infected with it. To test the ability to induce HLA-restricted T cell immune response against a mycobacterial antigen in humans by pDNA vaccination, we have used transgenic mice that express HLA class I (A*0201/Kb) or HLA class II (DRB1*0301) molecules. pDNA immunization with mycobacterial heat shock protein 65 (Mhsp65)-expressing plasmid (P3M.65) resulted in HLA-II-restricted, Ag-specific T cell-mediated immune responses characterized by proliferation and cytokine production. These T cell responses could be further augmented by the coinjection of P3M.65 and plasmid expressing murine GM-CSF. Furthermore, coimmunizing HLA-I transgenic mice with P3M.65 and a plasmid expressing murine IFN-γ induced a specific cytotoxic T lymphocyte response restricted by HLA-A2. These results represent the first evidence of a concomitant in vivo induction of HLA class I- as well as class II-restricted T cell responses by pDNA immunization, which is induced or augmented by the codelivery of cytokine-expressing plasmids, supporting its potential use in clinical trials.
Bacteriophage Receptor Binding Protein Based Assays for the Simultaneous Detection of Campylobacter jejuni and Campylobacter coli (2013)

Campylobacter jejuni and Campylobacter coli are the most common bacterial causes of foodborne gastroenteritis which is occasionally followed by a debilitating neuropathy known as Guillain-Barré syndrome. Rapid and specific detection of these pathogens is very important for effective control and quick treatment of infection. Most of the diagnostics available for these organisms are time consuming and require technical expertise with expensive instruments and reagents to perform. Bacteriophages bind to their host specifically through their receptor binding proteins (RBPs), which can be exploited for pathogen detection. We recently sequenced the genome of C. jejuni phage NCTC12673 and identified its putative host receptor binding protein, Gp047. In the current study, we localized the receptor binding domain to the C-terminal quarter of Gp047. CC-Gp047 could be produced recombinantly and was capable of agglutinating both C. jejuni and C. coli cells unlike the host range of the parent phage which is limited to a subset of C. jejuni isolates. The agglutination procedure could be performed within minutes on a glass slide at room temperature and was not hindered by the presence of buffers or nutrient media. This agglutination assay showed 100% specificity and the sensitivity was 95% for C. jejuni (n = 40) and 90% for C. coli (n = 19). CC-Gp047 was also expressed as a fusion with enhanced green fluorescent protein (EGFP). Chimeric EGFP_CC-Gp047 was able to specifically label C. jejuni and C. coli cells in mixed cultures allowing for the detection of these pathogens by fluorescent microscopy. This study describes a simple and rapid method for the detection of C. jejuni and C. coli using engineered phage RBPs and offers a promising new diagnostics platform for healthcare and surveillance laboratories.
Supplementary Figure 2 from Prohibitin Attenuates Colitis-Associated Tumorigenesis in Mice by Modulating p53 and STAT3 Apoptotic Responses (2023)

&lt;p&gt;PDF file - 76K, PHB Tg mice are less susceptible to CAC and mortality&lt;/p&gt;