gebhart/patrepeval huggingface dataset:
Topical H2 Antagonist Prevents Periodontitis in a Rabbit Model (2006)

Cimetidine is a powerful H2 receptor antagonist that eliminates histamine's effects on chemotaxis, phagocytosis, and superoxide anion production by phagocytes. The purpose of this study was to analyze the clinical and histopathological changes associated with experimental periodontitis in rabbits in response to topically applied cimetidine. Experimental periodontitis was induced in 21 New Zealand White rabbits using Porphyromonas gingivalis (10(9) CFU) topically applied three times a week for a 6-week period to previously ligatured teeth. Topical application of cimetidine in a liposome carrier for the prevention of periodontitis was evaluated in four groups of four animals each: 1, 10, and 100 mg/ml and no treatment (positive control). In addition, there was a vehicle group (n = 3) that received liposome preparation (carrier) only, and two animals with ligature application alone served as negative controls. Periodontal disease was quantified by direct visualization and radiographical evaluation of bone loss on defleshed skulls and by histological analyses of sections stained with hematoxylin-eosin and tartrate-resistant acid phosphatase. In the no-treatment (positive control) and liposome (vehicle) groups, direct visualization and radiological measurements revealed statistically significant bone loss compared to the negative control. Application of cimetidine at all concentrations tested inhibited inflammation and bone loss by >90%. Histological findings revealed that ligated sites of the positive control and vehicle groups showed significant reduction in bone level (P < 0.05) compared to the three cimetidine groups, with a marked decrease in inflammation. The findings of this study provide morphological and histological evidence that topically active cimetidine is a potent inhibitor of P. gingivalis-elicited periodontal inflammation, arresting and/or preventing tissue destruction and influencing cell populations present in the inflammatory cell infiltrate.
Case Studies in Application of Design of Experiments Methodology to Ice Basin Testing (2016)

Abstract This paper describes four case studies highlighting applications of Design of Experiments (DOE) methodology in ice basin testing. The case studies are (1) an investigation of methods for model ice ridge preparation and property testing, (2) managed first-year ridge interaction with an axisymmetric floater, (3) interaction of first-year ridges with a multi-leg GBS and (4) towing of a gravity-based structure and axisymmetric floater in ice. These experiments illustrate a different approach to ice basin testing. Rather than trying to reproduce natural conditions and scale up loads, critical design scenarios are isolated and DOE methodology is used to determine the most influential parameters on response quantities of interest.
Innovative lightweight baseplate solution for stable optical benches in space programmes (2008)

High precision space optics requires ultra stable lightweight platforms, which have to survive the launch loads and to maintain their stability under space environment. Such benches require a high planarity, small roughness and are usually made of the same material as the carried equipment. For space systems mass is a penalty, thus optical platforms are lightweighted by machining features. Besides of being not too mass efficient, this reduces significantly the load carrying capability of the base material. The challenge for us was to develop, qualify and deliver optical benches, providing a high mass reduction, while maintaining the load carrying capacity of the base material. Such an optical bench has been developed and built by Oerlikon Space and was equipped together with SESO with the high performing optical components for the flight model of the Aladin Mie Spectrometer for Astrium Toulouse. All tests have proven the high strength and stability of the adopted concept.
Candida albicans Is Not Always the Preferential Yeast Colonizing Humans: A Study in Wayampi Amerindians (2013)

In industrialized countries Candida albicans is considered the predominant commensal yeast of the human intestine, with approximately 40% prevalence in healthy adults. We discovered a highly original colonization pattern that challenges this current perception by studying in a 4- year interval a cohort of 151 Amerindians living in a remote community (French Guiana), and animals from their environment. The prevalence of C. albicans was persistently low (3% and 7% of yeast carriers). By contrast, Candida krusei and Saccharomyces cerevisiae were detected in over 30% of carriers. We showed that C. krusei and S. cerevisiae carriage was of food or environmental origin, whereas C. albicans carriage was associated with specific risk factors (being female and living in a crowded household). We also showed using whole-genome sequence comparison that C. albicans strains can persist in the intestinal tract of a healthy individual over a 4-year period.
Neural Task Graphs: Generalizing to Unseen Tasks From a Single Video Demonstration (2019)

Our goal is to generate a policy to complete an unseen task given just a single video demonstration of the task in a given domain. We hypothesize that to successfully generalize to unseen complex tasks from a single video demonstration, it is necessary to explicitly incorporate the compositional structure of the tasks into the model. To this end, we propose Neural Task Graph (NTG) Networks, which use conjugate task graph as the intermediate representation to modularize both the video demonstration and the derived policy. We empirically show NTG achieves inter-task generalization on two complex tasks: Block Stacking in BulletPhysics and Object Collection in AI2-THOR. NTG improves data efficiency with visual input as well as achieve strong generalization without the need for dense hierarchical supervision. We further show that similar performance trends hold when applied to real-world data. We show that NTG can effectively predict task structure on the JIGSAWS surgical dataset and generalize to unseen tasks.
Expression of a 50 kDa putative receptor for bovine viral diarrhea virus in bovine fetal tissues. (1998)

The expression of a 50 kDa bovine viral diarrhea virus putative receptor in different bovine fetal tissues from 3-month old fetuses was studied. The receptor expression was examined by immunocytochemical staining and by immunoblotting using antiidiotypic probe (anti-D89). Intense specific staining in enterocytes of the small and large intestines, cortical tubular epithelial cells of kidneys, respiratory epithelial cells of the trachea and esophageal mucosal epithelial cells was observed, demonstrating the strong expression of bovine viral diarrhea virus receptor in the tissues. Weak staining was found in cerebellum, thymus, spleen, liver, cerebrum, and lung tissues; however, heart tissues were negative. Immunoblotting results correlated with the immunoperoxidase staining assays. Thus, the expression levels of the receptor are variable in different tissues. This pattern of expression may provide clues to the pathogenic potential of bovine viral diarrhea virus in the bovine fetus.
Porosity Formation in Laser Welding of Tailored Blanks (2003)

&lt;div class="htmlview paragraph"&gt;For the laser welded tailored blanks (TBs), the formability of TBs depends on pores in the weld bead. Those pores are easily formed by CO&lt;sub&gt;2&lt;/sub&gt; laser but hardly observed by YAG laser. Based on a quantitative analysis of nitrogen content in the weld metal, gases in pores and the laser induced plasma, it is considered that high temperature of the plasma encourages dissolving nitrogen into the molten metal from the root surface and the dissolved nitrogen forms porosity due to an abrupt decreasing of nitrogen solubility at solidification of the molten metal. Also, the plume temperature in YAG laser welding is lower than the plasma temperature in CO&lt;sub&gt;2&lt;/sub&gt; laser welding and the nitrogen dissolution must therefore be suppressed in YAG laser welding.&lt;/div&gt;
Current Medical Ultrasound Technology (2012)

Medical ultrasound equipment is widely used in many fields of clinical medicine since ultrasound technology has the advantage of being non-invasive, easy-to-use, real-time, in addition, it can provide various types of information for morphological, functional and tissue characteristic diagnosis. From now on, home-care medicine will become more important for the healthy longevity society, and medical ultrasound technology will be utilized for precise and easy point-of-care diagnosis. Here, I give an outline of the latest technologies of medical ultrasound.
Energy-Sustainable Traffic Steering for 5G Mobile Networks (2017)

Renewable energy harvesting (EH) technology is expected to be pervasively utilized in the next generation (5G) mobile networks to support sustainable network developments and operations. However, the renewable energy supply is inherently random and intermittent, which could lead to energy outage, energy overflow, quality of service (QoS) degradation, etc. Accordingly, how to enhance renewable energy sustainability is a critical issue for green networking. To this end, an energy-sustainable traffic steering framework is proposed in this article, where the traffic load is dynamically adjusted to match with energy distributions in both spatial and temporal domains by means of inter- and intra-tier steering, caching and pushing. Case studies are carried out, which demonstrate the proposed framework can reduce on-grid energy demand while satisfying QoS requirements. Research topics and challenges of energy-sustainable traffic steering are also discussed.
Pathways to a Green Ammonia Future (2022)

ADVERTISEMENT RETURN TO ISSUEPREVEnergy FocusNEXTPathways to a Green Ammonia FutureBoreum LeeBoreum LeeDepartment of Chemical and Environmental Engineering, Yale University, New Haven, Connecticut 06520-8286, United StatesMore by Boreum Lee, Lea R. WinterLea R. WinterDepartment of Chemical and Environmental Engineering, Yale University, New Haven, Connecticut 06520-8286, United StatesMore by Lea R. Winterhttps://orcid.org/0000-0002-6409-788X, Hyunjun LeeHyunjun LeeSchool of Energy and Chemical Engineering, Ulsan National Institute of Science and Technology, Ulsan 44919, Republic of KoreaMore by Hyunjun Lee, Dongjun LimDongjun LimSchool of Energy and Chemical Engineering, Ulsan National Institute of Science and Technology, Ulsan 44919, Republic of KoreaMore by Dongjun Lim, Hankwon Lim*Hankwon LimSchool of Energy and Chemical Engineering, Ulsan National Institute of Science and Technology, Ulsan 44919, Republic of Korea*Phone: +82 (52) 217-2935. Email: [email protected]More by Hankwon Limhttps://orcid.org/0000-0002-1074-0251, and Menachem Elimelech*Menachem ElimelechDepartment of Chemical and Environmental Engineering, Yale University, New Haven, Connecticut 06520-8286, United States*Phone: +1 203-432-2789. Email: [email protected]More by Menachem Elimelechhttps://orcid.org/0000-0003-4186-1563Cite this: ACS Energy Lett. 2022, 7, 9, 3032–3038Publication Date (Web):August 19, 2022Publication History Received15 July 2022Accepted5 August 2022Published online19 August 2022Published inissue 9 September 2022https://pubs.acs.org/doi/10.1021/acsenergylett.2c01615https://doi.org/10.1021/acsenergylett.2c01615newsACS PublicationsCopyright © Published 2022 by American Chemical Society. This publication is available under these Terms of Use. Request reuse permissions This publication is free to access through this site. Learn MoreArticle Views18396Altmetric-Citations14LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail PDF (3 MB) Get e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information SUBJECTS:Electrical energy,Electrocatalysts,Electrolysis,Physical and chemical processes,Thin films Get e-Alerts
Network Layer Mobility: itecture and Survey (1996)

In this article we explore various network layer concepts that play a crucial role in the design of mobile networking systems. We show that mobility is essentially an address translation problem and is best resolved at the network layer. We describe services that must be supported at the network layer to carry out the task of address translation. Using these service primitives as building blocks, we describe a network-layer architecture which enables smooth integration of mobile end systems within the existing Internet. A summary of some of the key Mobile IP proposals is presented, and it is shown that each proposal can be viewed as a special case of the architecture outlined in this article.
Synthesis and Evaluation of a Library of Alternating Amphipathic Copolymers to Solubilize and Study Membrane Proteins (2021)

Amphipathic copolymers such as poly(styrene-maleic acid) (SMA) are promising tools for the facile extraction of membrane proteins (MPs) into native nanodiscs. Here, we designed and synthesized a library of well-defined alternating copolymers of SMA analogues in order to elucidate polymer properties that are important for MP solubilization and stability. MP extraction efficiency was determined using KcsA from E.coli membranes and general solubilization efficiency was investigated via turbidimetry experiments on membranes of E.coli, yeast mitochondria and synthetic lipids. Remarkably, halogenation of SMA copolymers dramatically improved solubilization efficiency in all systems, while substituents on the copolymer backbone improved resistance to Ca2+. Relevant polymer properties were found to include hydrophobic balance, size and positioning of substituents, rigidity and electronic effects. The library thus contributes to the rational design of copolymers for the study of MPs.
Generation of infinitely-long phase screens for modeling optical wave propagation through turbulence (2005)

Numerical modeling of optical wave propagation in atmospheric turbulence is traditionally performed by using the so-called "split" - operator method, where the influence of the propagation medium's refractive index inhomogeneities is accounted for only within a set of infinitely narrow phase distorting layers (phase screens). These phase screens are generated on a numerical grid of finite size, which corresponds to a rather narrow slice (spatial area) of atmospheric turbulence. In several important applications including laser target tracking, adaptive optics, and atmospheric imaging optical system performance depends on atmospheric turbulence within an extended area that significantly exceeds the area associated with the numerical grid. In this paper we discuss methods that allow the generation of a family of long (including infinitely long) phase screens representing an extended (in one direction) area of atmospheric turbulence-induced phase distortions. This technique also allows the generation of long phase screens with spatially inhomogeneous statistical characteristics. It can be applied to the numerical analysis of laser tracking and directed energy systems over long target trajectories.
Skeletal muscle metastases in neuroblastoma share common progenitors with primary tumor and biologically resemble stage MS disease (2023)

Children with neuroblastoma SMM have an excellent prognosis, with a clinical course suggestive of stage MS disease. Based on these results, the initial management of infants with non-MYCN-amplified NB with SMM could be watchful observation, which could eliminate or reduce exposure to genotoxic therapy.
A real time system for robust 3D voxel reconstruction of human motions (2002)

We present a multi-PC/camera system that can perform 3D reconstruction and ellipsoid fitting of moving humans in real time. The system consists of five cameras. Each camera is connected to a PC which locally extracts the silhouettes of the moving person in the image captured by the camera. The five silhouette images are then sent, via local network, to a host computer to perform 3D voxel-based reconstruction by an algorithm called SPOT. Ellipsoids are then used to fit the reconstructed data. By using a simple and user-friendly interface, the user can display and observe, in real time and from any view-point, the 3D models of the moving human body. With a rate of higher than 15 frames per second, the system is able to capture non-intrusively, a sequence of human motions.
AN APPROACH FOR ASSESSING DESIGN SYSTEMS - Design System Simulation and Analysis for Performance Assessment (2007)

This position paper presents our work in assessing engineering design systems in the field of microelectronics with respect to their performance and, more specifically, to productivity. Current mainstream process assessment systems show deficiencies of the representation and analysis when dealing with dynamic, self-optimizing processes. To overcome this, a project called PRODUKTIV+ has been created with the goal to develop a new approach. This approach is to create a model of a design system and simulate the colaborative behavior of the involved engineers using a system of cooperating, intelligent software agents. The assessment of a design system is then done based on the detailed simulation results.
Clinical and Finite Element Analysis of Acute Whiplash (2011)

Study Design: A prospective 1-year follow-up study of whiplash patients presenting with neurological signs/or symptoms (WADIII), and whiplash patients with neck pain but no neurologic findings (WADI/II). Objective: We hypothesize that WADI/II and WADIII are distinct entities, with regards to clinical presentation, pathoanatomy, and prognosis. Summary of Background Data: symptoms associated with whiplash injury range from mild neck pain (WADI/II), to injuries associated with neurologic sequellae (WADIII). To date, literature considers whiplash associated disorders (WAD) a single clinical and pathologic entity, with different grades of severity (WADI-IV). Methods: Thirty one subjects were divided into a WADIII study group and a WADI/II comparison group. All subjects underwent H&P, radiographic evaluations, and clinical outcome measures (collected at 3, 6, and 12 months). Statistical analysis was performed (Student T-test, Wilcoxon Signed-Rank test) with significance set at p=0.05. A finite element analysis (FEA) technology (SCOSIA©) was used to predict stresses within the neuraxis. Results: At day 0: Better neurologic assessments, functional performances, and higher quality-of-life measurements were noted in WADI/II compared to WADIII. VAS scores were comparable. At 12 months: Both groups reported improvements in neurologic status and disability symptoms. However functional recovery and quality-of-life measures significantly improved in WADIII, and conversely deteriorated in WADI/II along with notable worsening of pain symptoms. Litigation claims were comparable. FEA predicted higher stress within the neuraxis of WADIII, notably in subjects with preexisting stenosis and odontoid retroflexion. Conclusion: WADI/II and WADIII are distinct entities. Musculoskeletal injury precipitates WADI/II pain symptoms while neuronal stretching leads to WADIII neurologic injuries, which are mostly recoverable.
The effect of dicyandiamide on pasture nitrate concentration, yield and N offtake under high N loading in winter and spring (2012)

Abstract High nitrate ( ) concentrations in pastures and forages represent a health risk to grazing livestock. A field trial was conducted on the Lincoln University Dairy Farm, New Zealand, to investigate the effects of applying the nitrification inhibitor dicyandiamide (DCD) on soil extractable N and pasture concentrations in winter and spring. Treatments were control (T1), urea (T2), urea + DCD (T3), May urine + DCD (T4), August urine + DCD (T5), May urine (T6) and August urine (T7). Urine treatments were applied to the ryegrass‐white clover pasture in either May or August. The DCD treatments were applied at 10 kg DCD ha −1 in May and August and urea at 25 kg N ha −1 at selected intervals. Soil samples (0‐ to 75‐ and 75‐ to 150‐mm horizons) were taken regularly to monitor soil and ammonium ( ) levels. Six pasture harvests were conducted from August 2007 to March 2008 and samples analysed for ‐N concentrations and total N content. Application of DCD significantly ( P &lt; 0·001) increased total dry‐matter (DM) production by 39 and 42% for the autumn and spring urine treatments, respectively, compared to the urine‐alone treatments. In addition, the application of DCD also significantly ( P &lt; 0·001) increased DM yield by 12% on the urea‐only treatment. DCD significantly ( P &lt; 0·001) reduced pasture concentrations in both autumn‐ and spring‐applied urine treatments where DCD was applied. This was directly linked to reductions in soil , and increases in soil , from DCD application. The preferential uptake by pasture for ‐N over ‐N may also have been a contributing factor. DCD application can therefore substantially reduce pasture ‐N concentrations to safe levels under high N‐loading (urine patch) conditions.
Architectural Software Power Estimation Support for Power Aware Remote Processing (2004)

Mobile devices can reduce their energy consumption through power-aware remote processing. Software components running on battery-operated wireless nodes are migrated to wall-power wired remote servers. To increase the efficiency of power-aware remote processing, we propose a novel integrated estimator for software components' power and energy consumption. This adaptive estimator is based on a software component interface. The interface provides power and timing information. The unit is one of the main components in our framework for power-aware remote processing, providing information for efficient internal decision making whether software components can profit by migration and remote execution or not. We present results from our framework evaluated in Java environment and standard wearable computing hardware, using sample software components for AES encryption and decryption.