gebhart/patrepeval huggingface dataset:
Technique for Implantation of Chronic Indwelling Aortic Access Catheters (2006)

Thus, this dependable subcutaneous arterial access system provides a means for examining acute and long-term effects of environmental and pathophysiological influences in conscious dogs. These catheters have remained bidirectionally patent ongoing for more than 1 year and allowed infusion of agents and withdrawal of central arterial blood samples.
Development of High Power LEDs (2012)

Email Share Share with Facebook Tweet This Post on reddit Share with LinkedIn Add to CiteULike Add to Mendeley Add to BibSonomy Get Citation Copy Citation Text S. J. Hon, "Development of High Power LEDs," in Asia Communications and Photonics Conference, OSA Technical Digest (online) (Optica Publishing Group, 2012), paper ATh4F.3. Export Citation BibTex Endnote (RIS) HTML Plain Text Citation alert Save article
Circuits and systems education: viewpoint of GOLD and industry (2009)

This paper discusses circuits and systems (CAS) education, its strengths and shortcomings, and areas that need improvement from the perspective of two GOLD (graduates of the last decade) members and one industry member. The GOLD members highlight the need for hardware experiments, and active education methods such as self-learning through practices, and the importance of lab work to relate theory to practice, and also discuss the impact of new emerging technologies on educational reforms, also suggesting ways to get industry involved in the formulation of a new multidiscipline education curriculum. The GOLD members also discuss the impact of globalization on the CAS education in less- developed countries and the role of the IEEE CAS Society on the subject matter. The author from industry discusses the importance of CAS education, and contrary to the general belief, points out the importance of understanding the fundamentals of electrical engineering in industry. The author also discusses the importance of being flexible in a work environment, and establishing a broad knowledge in engineering to have a positive impact in the company.
Manipulation of Carrier–Mn<sup>2+</sup>Exchange Interaction in CdTe/CdSe Colloidal Quantum Dots by Controlled Positioning of Mn<sup>2+</sup>Impurities (2013)

Intentional inclusion of manganese ions (Mn2+) into colloidal quantum dots (CQDs) with precise positioning at a substitution lattice site provides a way to explore the interaction between photogenerated species (exciton, electron, hole) and Mn2+ spin states. We investigated the influence of Mn2+ impurity on the optical properties of CdTe/CdSe CQDs. Host CQDs exhibit a quasi-type-II characteristic, with asymmetric delocalization of the carriers over the entire core/shell structure. Mn2+ ions were precisely embedded either at the core or at the shell, using controlled layer-by-layer growth. Optical measurements carried out at cryogenic temperatures revealed a change in radiative lifetime, induced circular polarization, and energy split of exciton band-edge emission in the absence of an external magnetic field, when the Mn2+ ions were situated within the core. The results suggest the existence of a significant hole–Mn2+ exchange interaction and demonstrate a way to control band-edge optical properties in confined systems.
Nuclear localization signals, DNA binding, and transactivation properties of quail Pax-6 (Pax-QNR) isoforms. (1995)

We reported previously the characterization of Pax-QNR/Pax-6 products expressed in the avian neuroretina. Five proteins (48, 46, 43, 33, and 32 kDa) were characterized, among which the 33 and 32 kDa proteins are devoid of the paired domain. In contrast to the 48-kDa (containing an alternative paired exon 4a) and 46-kDa proteins exclusively located in the nucleus, the 43- (in which the paired exon 5 is spliced out), 33-, and 32-kDa proteins were also found in the cytoplasmic compartment. We report the identification of two nuclear targeting sequences: the basic LKRKLQR region (amino acids 206-212) located in the NH2 terminus of the homeodomain used by the p43 and 33/32 kDa proteins; and the paired exon 5 sequence. A case of human aniridia, where arginine 208 of LKRKLQR is mutated into a tryptophan, has been reported recently. We introduced this mutation into the Pax-QNR p46, p43, and p33/32 proteins. No effect on the nuclear localization or in transactivation potential of the proteins could be observed. Among the several Pax-QNR isoforms characterized, only p46 exhibited DNA-binding and transactivating properties on the Pax-QNR promoter. Deletions of parts of the protein showed that the Pax-6 transactivation domain is located in the carboxyl terminus of the protein.
Client-centric fractional frequency reuse based on user cooperation in OFDMA networks (2008)

This paper proposes client-centric fractional frequency reuse (CC-FFR) techniques for interference mitigation in OFDMA-based cellular wireless networks. In this framework, clients exploit their peer-to-peer connectivity to bargain for spectrum by exchanging channel quality indicator (CQI) metrics with the objective of jointly finding viable sub-channel allocations with low co-channel interference and high throughput. We analyze both the unconstrained case of greedily maximizing system capacity, as well as the fair case where optimization is performed subject to minimum rate constraints per user. Our numerical results, based on realistic channel propagation models and IEEE 802.16-based system parameters, show a promising performance gain that motivates to further investigate the potential of using user cooperation for co-channel interference mitigation.
Left ventricular function during porcine-resuscitated septic shock with pre-existing atherosclerosis (2016)

The data of the present study are in conflict with previously published data from healthy animal models, most likely as a result of ongoing resuscitation including noradrenaline treatment or intrinsic pathophysiologic processes of the pre-existing atherosclerosis. Moreover, increased nitrotyrosine formation and decreased expression of CSE suggest the implication of augmented oxidative/nitrosative stress and/or reduced bioavailability of nitric oxide as well as diminished endogenous H2S release in the pathophysiology of septic cardiomyopathy.
Detection of Human Anti-Annexin Autoantibodies by Enzyme Immunoassays (1992)

Annexins belong to a family of proteins characterized by calcium-dependent binding to the cytoskeleton and phospholipid surfaces. Basing on these properties annexins are discussed to be involved in the regulation of cytodynamic, anticoagulatory and antiinflammatory processes. Since autoantibodies against annexin I had been detected in patients suffering from inflammatory or autoimmune diseases, an impact on the pathophysiological outcome was assumed. Therefore we developed solid phase, enzyme-linked immunoassays for the quantitative determination of autoantibodies directed against six members of the annexin family. Some preliminary results obtained from sera of patients with malignant melanoma show a quite frequent presence of such autoantibodies. These data suggest that autoantibodies are generated against all annexins. Furthermore, in the individual patient autoantibodies of the IgG-type are monospecific, while about 1/4 of the IgM-type are directed against several annexins. These observations imply that for investigation of anti-annexin autoantibodies in inflammatory and autoimmune diseases as well as cancer all members of the annexin family have to be taken into consideration.
In the Wake of Hurricane Isabel: A Prospective Study of Postevent Trauma and Injury Control Strategies (2005)

Preventing hurricane-related injuries (HRI) has historically centered on the pre-event and event phases of the disaster. To date, no study has focused on injuries occurring during the postevent phase. We examined HRI that occurred after Hurricane Isabel struck a U.S. urban city. HRI presenting 1 week prior to the hurricane were collected from emergency department electronic records. HRI that presented to our level 1 trauma center were prospectively collected for 1 week after the hurricane. Nine hundred seventy-eight patients with possible HRI were identified. Fifty-one patients with trauma directly attributed to the hurricane were used for analysis. The number of HRI occurring before, during, and after the hurricane were 7 (14%), 3 (6%), and 41 (80%), respectively. The majority of HRI (37%) occurred on posthurricane day 1. Head, chest, upper and lower extremities accounted for 9 (18%), 8 (16%), 13 (26%), and 14 (28%) of HRI. More than one third of HRI patients were admitted to the hospital, and 12 (24%) underwent an operation. The average hospital length of stay was 4.7 days. Of our trauma alerts, 75 per cent had an Injury Severity Score (ISS) >8, and 20 per cent had an ISS >15. Tree-related injuries (TRI) accounted for 59 per cent of HRI. Males, ages 50-60, had the highest incidence of injury (63%). Significant injuries occur in the wake of a hurricane. Optimization of disaster preparation must include prevention strategies targeted to the postevent recovery phase of disasters.
End-to-end performance improvements for multi-hop ad-hoc wireless networks (2004)

In this paper, we make MAC protocol improvements for performance enhancement of multihop ad-hoc wireless networks. A node in ad-hoc wireless networks can transmit a packet only when the medium is available, and while a packet is being transmitted, no other node is allowed to transmit a packet if they are in carrier sensing range. Carrier sensing range can be divided into two disjoint areas of transmission range and carrier sensing zone, and we address the importance of the protocol procedure when a node is in carrier sensing zone. The characteristic of the carrier sensing zone is that a node can not know when the remaining time of the ongoing transmission session expires or exactly when the media becomes available. Current MAC protocol does not behave in much different way between when a node is in transmission range and in carrier sensing zone. We have conducted a comprehensive simulation to study the performance improvements. The simulation results indicate that the performance is increased and the number of dropped packets due to collision is significantly reduced as much as a half.
On human remains (2010)

Creating digital archives of personal and family artifacts is an area of growing interest, but which seemingly is often not supported by a thorough understanding of current home archiving practice. In this article we seek to excavate the home archive, exploring those things that people choose to keep rather than simply accumulate. Based on extensive field research in family homes we present an investigation of the kinds of sentimental objects, both physical and digital, to be found in homes, and through in-depth interviews with family members we explore the values behind archiving practices, explaining why and how sentimental artefacts are kept. In doing this we wish to highlight the polysemous nature of things and to argue that archiving practice in the home is not solely concerned with the invocation of memory. In support of this we show how sentimental artifacts are also used to connect with others, to define the self and the family, to fulfill obligations and, quite conversely to efforts of remembering, to safely forget. Such values are fundamental to family life where archiving takes place and consequently we explore how home archiving is achieved as a familial practice in the negotiated spaces of the home. From this grounded understanding of existing practices and values, in context, we derive requirements and implications for the design of future forms of domestic archiving technology.
Time Coordinated V2I Communications and Handover for WAVE Networks (2011)

A wide variety of information technology (IT) services will become available for vehicles through the IEEE 802.11p, IEEE 1609, and wireless access in vehicular environment (WAVE) standards, and naturally the need for service handover will become a necessity. For WAVE networks, a time coordinated medium access control (MAC) protocol named WAVE point coordination function (WPCF) is proposed in this paper. The mathematical derivations and simulation analysis demonstrate that the proposed WPCF protocol can significantly enhance the utilization efficiency and can support more users based on an equal-length access period when compared to point coordination function (PCF), enhanced distributed channel access (EDCA), or hybrid coordination function (HCF) controlled channel access (HCCA) for vehicle to infrastructure (V2I) communications. The paper also demonstrates the effectiveness of the proposed WAVE handover controller (WHC) and WPCF in minimizing service disconnection time when used for V2I handover. In addition, technical enhancements and messages are added to enable seamless communication services over soft-handover (SHO), and enable minimum handover delay in hard-handover (HHO) situations. The mathematical performance evaluation and the simulation results show that the proposed scheme can significantly improve the handover latency compared to the performance that can be delivered by the current protocols.
The synthesis of polyfluoroalkyl substituted pyrroles as building blocks for obtaining fluorinated pyrrolidine-containing alkaloids (2020)

Aim. To study the synthetic potential of cyclization of N-(β-polyfluoroacyl)vinyl derivatives of proline and N-substituted glycines into polyfluoroalkyl pyrroles, which are useful intermediates to fluorinated pyrrolidine alkaloids.Results and discussion. N-(β-Polyfluoroacyl)vinyl derivatives of proline and N-substituted glycines have been obtained and transformed to polyfluoroalkyl-containing pyrroles using acetic or trifluoroacetic anhydride.Experimental part. N-(β-Polyfluoroacyl)vinyl derivatives of proline and N-substituted glycines were obtained from β-alkoxyvinyl polyfluoroalkyl ketones and the corresponding amino acids. The enaminones so obtained were transformed to polyfluoroalkyl-containing pyrroles with acetic or trifluoroacetic anhydride. The structure and composition of the compounds synthesized were proven by the data of 1Н and 19F NMR spectroscopy and elemental analysis.Conclusions. It has been shown that an increase of steric hindrance in N-(β-polyfluoroacyl)vinyl derivatives of proline (the perfluoroethyl group instead of the trifluoromethyl group) and N-substituted glycines (replacement of the N-methyl group with the N-benzyl group) gives mainly polyfluoroacyl pyrrolyl acetates when heating in acetic anhydride. Polyfluoroalkyl-containing pyrroles have been obtained by treatment of N-(β-polyfluoroacyl)vinyl derivatives of proline and glycine with trifluoroacetic anhydride.Received: 01.04.2020Revised: 05.05.2020Accepted: 29.05.2020
Patellar tendon orientation and patellar tracking in male and female knees (2009)

Knowledge of patellofemoral joint biomechanics is important for understanding sex-related dimorphism in patellofemoral pathologies and advancement of related treatments. We evaluated the hypotheses that sex differences exist in patellar tendon (PT) orientation and patellar tracking during weight-bearing knee flexion and that they relate to differences in tibiofemoral rotation. The PT orientation and patellar tracking were measured in healthy subjects (18 male, 13 female) during weight-bearing knee flexion, using magnetic resonance and dual fluoroscopic imaging. These data were analyzed for sex differences and correlation with previously reported tibiofemoral rotation data. The results indicated a significant effect of sex on PT orientation, particularly at low flexion angles. In females, the PT was oriented more anteriorly in the sagittal plane, more medially in the coronal plane, and showed greater external tilt in the transverse plane of the tibia (p < 0.05). Significant correlations between tibiofemoral rotation and PT orientation (p < 0.01) indicated that sex differences in coronal and transverse plane orientation of the PT relate to differences in tibiofemoral rotation. Patellar tracking did not show significant sex differences or correlation to tibiofemoral rotation. Further studies are warranted to determine implications for patellofemoral pathologies and treatments like total knee arthroplasty.
Do Human Lumbar Discs Reconstitute After Chemonucleolysis? (1999)

Human lumbar discs do not reconstitute after chemonucleolysis. Because the long-term temporal course of disc height in patients is in disagreement with observations from animal experiments, caution is suggested when generalizing results from animal studies to humans.
Summary Abstract: Surface reaction enhancement via low energy electron bombardment and secondary electron emission (1987)

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Reversible 300 K Ferromagnetic Ordering in a Diluted Magnetic Semiconductor (2004)

Reversible 300 K ferromagnetic ordering in a diluted magnetic semiconductor, Co2+:ZnO, is achieved by lattice incorporation and removal of the native n-type defect, interstitial Zn, resulting in “off” and “on” states (Figure, red triangles and blue circles). Spectroscopic and magnetic data implicate a double-exchange mechanism for ferromagnetism. These results suggest new opportunities for integrating magnetism and conductivity in semiconductor sensor or spin-based electronics devices. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2089/2004/c0456_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
Transurethral ultrasound catheter-based transducer with flexible polyimide joints (2009)

Transurethral ultrasound (TUUS) may improve prostate imaging by providing real-time volumetric imagery from directly within the prostate. A transurethral ultrasound transducer prototype was developed that features a cylindrical 2D array of piezoelectric elements that can be integrated with a catheter body. Fabrication of the transducer was made possible with a microfabrication process that allows the array to be rolled and wrapped circumferentially. The transducer array prototype features bulk lead zirconatetitanate (PZT) elements mounted on an array of silicon islands connected by flexible patterned polyimide joints. A preliminary image reconstruction simulation, developed specifically for the cylindrical architecture was performed to demonstrate the potential resolving capability in the prostate environment. Together the results of the transducer fabrication and image reconstruction indicate that the cylindrical transducer array approach is feasible for TUUS. Future clinical application of the technology may lead to considerable improvement in prostate imaging, image guidance, and monitoring as a new high resolution, real-time imaging tool.
Biosynthesis of 12(S)-hydroxyeicosatetraenoic acid by B16 amelanotic melanoma cells is a determinant of their metastatic potential. (1994)

Biosynthesis of 12(S)-HETE by tumor cells is a determinant of their metastatic potential and inhibition of 12(S)-HETE biosynthesis in tumor cells may be a crucial target for intervening in metastasis.
Educational Initiative on Critical Bleeding in Trauma: Chicago, July 11–13, 2008 (2010)

The Educational Initiative on Critical Bleeding in Trauma was formed to assess current data and to guide future research and practice in the management of coagulopathy after severe trauma. The Educational Initiative on Critical Bleeding in Trauma recently published structured literature reviews on animal models and mechanisms of trauma-associated coagulopathy and the results of a survey of international clinical practice. The authors convened a symposium in July 2008 and invited researchers and opinion leaders in trauma care, transfusion medicine, and coagulation research to discuss current understanding and management and to identify future areas of exploration. This document reviews the content and conclusions of the meeting. The association between trauma and bleeding from patient registries, basic science, and clinical studies was confirmed, as was the association between the coagulopathy that presents early after major injury and excess mortality. Meeting participants identified the need for consensus definitions and common terminology to describe coagulopathy after trauma, including the term acute coagulopathy of trauma shock to describe the early coagulopathy induced by tissue injury/shock and the global term trauma-induced coagulopathy to describe coagulopathy after injury and its sequelae (loss, consumption, acidemia, acute coagulopathy, and dilution). Other conclusions included the need for increased clinical awareness, new methods and tools for early diagnosis, consistent early preventative strategies, and evidence-based therapies for these conditions.
Supplementary Figure from Improved T-cell Immunity Following Neoadjuvant Chemotherapy in Ovarian Cancer (2023)

Supplementary Figure from Improved T-cell Immunity Following Neoadjuvant Chemotherapy in Ovarian Cancer
Effects of Hydrogen Peroxide on Intergranular Stress Corrosion Cracking of Stainless Steel in High Temperature Water, (I) Effects of Hydrogen Peroxide on Electrochemical Corrosion Potential of Stainless Steel. (1998)

In order to determine effects of hydrogen peroxide on stress corrosion cracking of structural materials in the primary cooling systems of boiling water reactors, a high temperature high pressure water loop with controlled hydrogen peroxide concentrations and lower possible oxygen concentrations has been fabricated. Test specimens are installed in a stainless steel autoclave which has poly tetra-fluoro-ethylene (PTFE) inner liner to prevent decomposition of hydrogen peroxide on the autoclave surfaces. Hydrogen peroxide is injected into the autoclave inlet through the injection line which also has PTFE inner liner. The concentration of hydrogen peroxide is measured at the autoclave outlet by sampling water via the PTFE-lined sampling line. More than 65% of the injected hydrogen peroxide remains at the autoclave outlet at elevated temperature (288°C). Electrochemical corrosion potential (ECP) of stainless steel is then measured in the autoclave while changing hydrogen peroxide and oxygen concentrations. From these measurements it is concluded that, at the same oxidant concentration: (1) ECP of stainless steel exposed to hydrogen peroxide is higher than that exposed to oxygen; (2) ECP is much affected by specimen surfaces; and (3) ECP shows a hysteresis pattern for on its concentration dependence. ECP of stainless steel with an oxidized surface formed under high hydrogen peroxide concentration is much higher than that with a mechanically polished surface and it is less affected by oxidant species and their concentrations.
Structural organization of the C1a-e-c supercomplex within the ciliary central apparatus (2019)

Nearly all motile cilia contain a central apparatus (CA) composed of two connected singlet microtubules with attached projections that play crucial roles in regulating ciliary motility. Defects in CA assembly usually result in motility-impaired or paralyzed cilia, which in humans causes disease. Despite their importance, the protein composition and functions of the CA projections are largely unknown. Here, we integrated biochemical and genetic approaches with cryo-electron tomography to compare the CA of wild-type <i>Chlamydomonas</i> with CA mutants. We identified a large (>2 MD) complex, the C1a-e-c supercomplex, that requires the PF16 protein for assembly and contains the CA components FAP76, FAP81, FAP92, and FAP216. We localized these subunits within the supercomplex using nanogold labeling and show that loss of any one of them results in impaired ciliary motility. These data provide insight into the subunit organization and 3D structure of the CA, which is a prerequisite for understanding the molecular mechanisms by which the CA regulates ciliary beating.