gebhart/patrepeval huggingface dataset:
[Preparation of BiOCl-(NH<sub>4</sub>)<sub>3</sub>PW<sub>12</sub>O<sub>40</sub> Photocatalyst and a Mechanism for Photocatalytic Degradation of Organic Pollutants]. (2019)

The separation efficiency of photogenerated electrons and holes is the key to photocatalytic performance. Layered BiOCl is a kind of newly exploited efficient photocatalyst, but its wide-spread practical application is hindered by the rapid recombination of photogenerated electron-hole pairs and low quantum efficiency. In this study, we prepared a composite photocatalyst via a hydrothermal method in which (NH<sub>4</sub>)<sub>3</sub>PW<sub>12</sub>O<sub>40</sub> (NH<sub>4</sub>PTA) is the acceptor of photoelectrons from BiOCl. The photocatalytic performance of variants of BiOCl-NH<sub>4</sub>PTA was evaluated by the removal efficiency of methyl orange (MO). The experimental results showed that the BiOCl-NH<sub>4</sub>PTA[<i>n</i> (Bi):<i>n</i> (W)=1:1] had the best photocatalytic activity under the irradiation of sunlight simulated by xenon light. The photocatalytic mechanism was investigated using the reactive species trapping experiments. It was found that MO could be photodegraded by,·OH, and holes over BiOCl. Differently, and·OH were the dominant reactive species for the reactions over the composite photocatalyst. It was proved that NH<sub>4</sub>PTA was the acceptor of photoelectrons by the XPS on the photocatalyst before and after reaction. The photocurrent test verified the superior photocatalysis of BiOCl-NH<sub>4</sub>PTA which was attributed to the efficient separation of electron-hole pairs.
Analyse et Caractérisation du Système de Vision d'une Plateforme de Micromanipulation (2004)

Une plateforme de manipulation adaptée à des composants de 5 à 50µm a été développée dans le but d’étudier et d’optimiser les performances de répétabilité de positionnement. Elle contient un robot de haute précision ainsi qu’une interface permettant d’adapter différents types de préhenseur. Un microscope est utilisé comme système de mesure. Afin de calibrer le système de vision, un pattern "dynamique" a été implémenté, il permet d’obtenir la relation entre le système de coordonnées du microscope et celui du robot et s’affranchit des erreurs d’alignement entre le pattern de référence et le robot. Les méthodes d’autofocus et de détection de pièces ne nécessitent que peu d’information a priori. La détection du préhenseur se fait en deux phases, permettant d’obtenir des données concernant son orientation et une localisation précise. Les méthodes de mesure implémentées permettent de localiser les éléments à manipuler et le préhenseur avec des précisions de l’ordre de 100nm.
Results of TRIO-14, a phase II, multicenter, randomized, placebo-controlled trial of carboplatin-paclitaxel versus carboplatin-paclitaxel-ganitumab in newly diagnosed epithelial ovarian cancer (2021)

Addition of ganitumab to CP chemotherapy in primary EOC did not improve PFS. Our results do not support further study of ganitumab in unselected EOC patients.
Regulation of static and dynamic ocular alignment in patients with trochlear nerve pareses (1995)

Ocular alignment and saccades were studied in seven patients with trochlear nerve pareses, before and after strabismus surgery. Prior to surgery, a position-dependent vertical ocular misalignment was present, and downward saccades were hypometric in the paretic eye. Strabismus surgery reduced the magnitude and position-dependence of the static misalignment. Saccade conjugacy improved in the patients with congenital pareses, and in the patient with a gradual-onset acquired paresis, but less improvement occurred in subjects with traumatic pareses. The post-operative change in saccade conjugacy relative to the change in static alignment correlated with pre-operative vertical vergence, suggesting that changes in saccade yoking depend on an interaction between saccades and vertical vergence.
Fluctuations in Fabaceae mitochondrial genome size and content are both ancient and recent (2019)

This study represents the most exhaustive analysis of Fabaceae mitogenomes so far, and extends the understanding the dynamic variation in size and gene/intron content. The four newly sequenced mitogenomes reported here expands the phylogenetic coverage to four subfamilies. The family has experienced multiple mitogenome size fluctuations in both ancient and recent times. The causes of these size variations are distinct in different lineages. Fabaceae mitogenomes experienced extensive size fluctuation by recruitment of exogenous DNA and duplication of native mitochondrial DNA.
An Intrinsically Digital Amplification Scheme for Hearing Aids (2005)

Results for linear and wide-dynamic range compression were compared with a new 64-channel digital amplification strategy in three separate studies. The new strategy addresses the requirements of the hearing aid user with efficient computations on an open-platform digital signal processor (DSP). The new amplification strategy is not modeled on prior analog strategies like compression and linear amplification, but uses statistical analysis of the signal to optimize the output dynamic range in each frequency band independently. Using the open-platform DSP processor also provided the opportunity for blind trial comparisons of the different processing schemes in BTE and ITE devices of a high commercial standard. The speech perception scores and questionnaire results show that it is possible to provide improved audibility for sound in many narrow frequency bands while simultaneously improving comfort, speech intelligibility in noise, and sound quality.
Ultrashort laser pulse cell manipulation using nano- and micro- materials (2010)

The delivery of extra cellular molecules into cells is essential for cell manipulation. For this purpose genetic materials (DNA/RNA) or proteins have to overcome the impermeable cell membrane. To increase the delivery efficiency and cell viability of common methods different nano- and micro material based approaches were applied. To manipulate the cells, the membrane is in contact with the biocompatible material. Due to a field enhancement of the laser light at the material and the resulting effect the cell membrane gets perforated and extracellular molecules can diffuse into the cytoplasm. Membrane impermeable dyes, fluorescent labelled siRNA, as well as plasmid vectors encoded for GFP expression were used as an indicator for successful perforation or transfection, respectively. Dependent on the used material, perforation efficiencies over 90 % with a cell viability of about 80 % can be achieved. Additionally, we observed similar efficiencies for siRNA transfection. Due to the larger molecule size and the essential transport of the DNA into the nucleus cells are more difficult to transfect with GFP plasmid vectors. Proof of principle experiments show promising and adequate efficiencies by applying micro materials for plasmid vector transfection. For all methods a weakly focused fs laser beam is used to enable a high manipulation throughput for adherent and suspension cells. Furthermore, with these alternative optical manipulation methods it is possible to perforate the membrane of sensitive cell types such as primary and stem cells with a high viability.
Mechanical evaluation and cell response of woven polyetheretherketone scaffolds (2012)

Polyetheretherketone (PEEK) is a high performance polymer, with high melting temperature and high resistance to wear. PEEK biomedical devices are typically manufactured to produce nonflexible structures. In this study, we fabricated flexible PEEK scaffolds from multifilament and monofilament yarns, using weaving technologies. Scaffolds were compared for structural and mechanical properties, and assessed for in vitro biological response to L929 mouse fibroblast cells. PEEK scaffolds were found to support fibroblast cell attachment and proliferation, with similar cell numbers to a polyethylene terephthalate scaffold. The large pores (261-280 μm) of the monofilament scaffold prevented pore coverage by cells, confining cells to filaments, whereas the smaller pores (81-100 μm) of the multifilament scaffold permitted partial pore coverage. Poor cell adhesion, due to large filament curvature angles, created a checkered pattern on the woven surface, a previously undocumented phenomenon. The multifilament scaffold was found to be lighter, thinner, and less porous, with better mechanical properties (load at break: 657 N, elastic recovery: 66%, burst strength: 492 N) than the monofilament scaffold (load at break: 534 N, elastic recovery: 30%, burst strength: 401 N). Results indicate that flexible PEEK woven structures may find application as tissue engineering scaffolds, particularly for engineering soft tissues.
Temperature and Voltage Estimation Using Ring-Oscillator-Based Monitor for Field Test (2014)

Field test is performed in diverse environments, in which temperature varies across a wide range. As temperature affects a circuit delay greatly, accurate temperature monitors are required. They should be placed at various locations on a chip including hot spots. This paper proposes a flexible ring-oscillator-based monitor that accurately measures voltage as well as temperature at the same time. The measurement accuracy was confirmed by circuit simulation for 180 nm, 90 nm and 45 nm technologies. An experiment using test chips with 180 nm technology shows its feasibility.
A 12-bit 500 MHz GaAs MESFET digital-to-analog converter with p+ ohmic contact isolation (1992)

Thesis (M.S.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 1992.
Perceptual navigation strategy: a unified approach to interception of ground balls and fly balls (2004)

In previous work, we demonstrated the feasibility of perceptual navigation algorithms used to intercept fly balls. In this paper we expand the optical acceleration cancellation heuristic to also intercept ground balls. We used computer simulations and experiments with mobile robots with various bail trajectories and different initial positions of the fielder to test our new model. A new robotic system with improved vision and faster processing was developed for experimentally intercepting ground balls. The results support the generality of viewer based interception heuristics for both fly balls and ground balls.
Characterization of a Tree Shrew Herpesvirus Isolated from a Lymphosarcoma (1979)

SUMMARY A herpesvirus was isolated from a lymphosarcoma culture of tree shrews (Tupaia belangeri) and termed Tupaia herpesvirus 2 (THV-2). Electron microscopy of THV-2 revealed the presence of virus particles with nucleocapsids of about 100 nm surrounded by large envelopes compatible with virions of the herpesvirus group. An extensive host range study revealed the Tupaia embryonic fibroblasts are the cells of choice for the efficient propagation of THV-2. This cell line was used for the continued propagation and plaque assay of THV-2. The mol. wt. of the virus DNA was found to be 100 × 106. The buoyant density of THV-2 was 1.724 g/ml. The DNA of THV-2 was compared to the DNA of herpes simplex virus (HSV) and to another previously isolated herpesvirus from apparently healthy tree shrews (THV-1). The analysis was carried out using the restriction endonuclease EcoRI and the cleavage pattern of THV-2 DNA resulted in DNA fragments which were different from those of HSV-1 DNA and distinguishable from the DNA of THV-1.
Optical harmonic generation in monolayer group-VI transition metal dichalcogenides (2018)

Monolayer transition metal dichalcogenides (TMDs) exhibit high nonlinear optical (NLO) susceptibilities. Experiments on ${\mathrm{MoS}}_{2}$ have indeed revealed very large second-order (${\ensuremath{\chi}}^{(2)}$) and third-order (${\ensuremath{\chi}}^{(3)}$) optical susceptibilities. However, third-harmonic generation results of other layered TMDs have not been reported. Furthermore, the reported ${\ensuremath{\chi}}^{(2)}$ and ${\ensuremath{\chi}}^{(3)}$ of ${\mathrm{MoS}}_{2}$ vary by several orders of magnitude, and a reliable quantitative comparison of optical nonlinearities across different TMDs has remained elusive. Here, we investigate second- and third-harmonic generation, and three-photon photoluminescence in TMDs. Specifically, we present an experimental study of ${\ensuremath{\chi}}^{(2)}$ and ${\ensuremath{\chi}}^{(3)}$ of four common TMD materials (${\mathrm{MoS}}_{2}$, ${\mathrm{MoSe}}_{2}$, ${\mathrm{WS}}_{2}$, and ${\mathrm{WSe}}_{2}$) by placing different TMD flakes in close proximity to each other on a common substrate, allowing their NLO properties to be accurately obtained from a single measurement. ${\ensuremath{\chi}}^{(2)}$ and ${\ensuremath{\chi}}^{(3)}$ of the four monolayer TMDs have been compared, indicating that they exhibit distinct NLO responses. We further present theoretical simulations of these susceptibilities in qualitative agreement with the measurements. Our comparative studies of the NLO responses of different two-dimensional layered materials allow us to select the best candidates for atomic-scale nonlinear photonic applications, such as frequency conversion and all-optical signal processing.
Cyclin pathway genomic alterations across 5,356 prostate cancers. (2020)

179 Background: The cyclin pathway is comprised of possible targetable alterations as well as resistant alterations that affect treatment, including hormonal agents. We describe the landscape of cyclin genomic alterations in prostate cancer. Methods: Consecutive samples were analyzed in a CLIA-certified laboratory using comprehensive genomic profiling (CGP) performed by next-generation sequencing (315 genes, &gt;500X coverage). We describe alterations in activating genes (Table) and co-alterations in resistant genes ( RB1 and CCNE1) (related to cyclin inhibition) and androgen receptor ( AR). Results: Alterations in any cyclin pathway genes were found in 9.7% of the 5,356 tumors analyzed. Frequent alterations included CCND1 amplification (4.2%) and CDKN2A and B loss (2.4% each). Frequencies were substantially different according to prostate cancer histology (Table). The majority of alterations were copy number changes. Alterations in possible resistance genes, RB1 and CCNE1 were detected in 9.7% (up to 54.6% in neuroendocrine) and 1.2% of cases, respectively, while AR alterations were seen in 20.9% (up to 27.3% in anaplastic). Co-occurrence analysis demonstrated a lower likelihood of concomitant vs. isolated alterations in cyclin activating and resistance pathway (odds ratio (OR), 0.44, p&lt;0.001). Conversely, we detected a higher likelihood of co-occurrence between AR and cyclin alterations (OR 1.79, p&lt;0.001). Conclusions: Cyclin pathway genomic abnormalities were observed in about 10% of prostate cancer tumors, and are more frequently associated with concomitant AR alterations and absence of co-alterations associated with resistance to cyclin inhibition.[Table: see text]
Multiheterodyne detection for self-referenced characterization of complex arbitrary waveforms from largely detuned optical frequency combs (2012)

Recently, it has been demonstrated that by considering a larger portion of the RF comb, a self-referenced measurement of each optical comb can be recovered, thus eliminating the need for a known reference with flat phase. In this manuscript, a more general form of this technique is explored, in which the mode spacings of the two unknown comb sources are detuned from each other by a factor of two or greater. This is a case of interest, seeing as how arbitrary waveforms generated from spectral modulation of OFCs which one might wish to characterize regularly exceed 10's of GHz rates, whereas the self-referenced, carrier-envelope offset stabilized sources which provide absolute knowledge of the optical frequencies involved in the multiheterodyne process are most commonly found in the sub-GHz repetition rate regime.
Studies on the effects of thyristor dynamic extinction angle on HVDC commutation failure (2017)

This paper focuses on the key technology of ultra high voltage direct current (UHVDC) converter valve equipment which is resistant to commutation failures. The simulation model is established, which can reflect the whole turn-off process of thyristor. The paper also offers the simulation models of converter valve model and of the double-fed high voltage direct current (HVDC) system. The transient fault and the failure mechanism of commutation failure are studied. The internal and external factors that affect commutation failure are analyzed in depth and the impact of operating conditions on commutation failure is quantified. The calculation method of the thyristor dynamic turn-off time and the related key technical indexes are proposed to optimize the commutation characteristics of the high power thyristor. This paper presents the method of intelligent trigger detection, such as forward voltage monitoring method, turn-off angle direct measurement method and minimum turn-off angle estimation method, together with their application approach in multi-infeed HVDC system (MIDC). The intelligent trigger monitoring device and the converter valve module prototype which is resistant to commutation failure are developed, and then verified by functional test.
Prevalence and genotypes of hepatitis C virus among injecting drug users from Salvador-BA, Brazil (2010)

Hepatitis C virus (HCV) is the major infectious disease agent among injecting drug users (IDUs), with seroprevalence ranging from 50-90%. In this paper, serological and virological parameters were investigated among 194 IDUs, 94 ex-IDUs and 95 non-IDUs that were sampled by the "snowball" technique in three localities renowned for both intense drug use and trafficking activities in Salvador, Brazil. The majority of the participants were male, but sex and mean age differed significantly between IDUs/ex-IDUs and non-IDUs (p < 0.05). Anti-HCV screening revealed that 35.6%, 29.8% and 5.3% of samples from IDUs, ex-IDUs and non-IDUs, respectively, were seropositive. HCV-RNA detection confirmed that the prevalence of infection was 29.4%, 21.3% and 5.3% for IDUs, ex-IDUs and non-IDUs, respectively. Genotyping analysis among IDUs/ex-IDUs determined that 76.9% were infected with genotype 1, 18.5% with genotype 3 and 4.6% with a mixed genotype; this result differed significantly from non-IDUs, where genotype 3 was the most frequent (60%), followed by genotype 1 (20%) and a mixed genotype (20%). We report a significantly higher prevalence of HCV infection in IDUs/ex-IDUs compared to the control group (p < 0.001). Although the sample size of our study was small, the differences in HCV genotype distribution reported herein for IDUs/ex-IDUs and non-IDUs warrant further investigation.
Thermal lensing in diode-pumped ytterbium Lasers-Part II: evaluation of quantum efficiencies and thermo-optic coefficients (2004)

A theoretical and experimental study of thermal lensing in Yb-doped crystals is presented. This papers follows the presentation of theoretical considerations and experimental wavefront measurements, which have been the subject of Part I. In this paper, we study the evolution of thermal lensing versus absorbed pump power, and we derive two parameters valuable for laser design and power scaling. The quantum efficiency and the thermo-optic coefficient, in Yb-doped YAG, GGG, GdCOB, YCOB, KGW and YSO. The clear difference between thermal lensing under lasing and nonlasing conditions is the proof that nonradiative effects occur in all the crystals under investigation. An analytical model which takes into account the laser extraction efficiency enables to explain all the experimental features and allows to infer the fluorescence quantum efficiency of the samples (in the range 0.7-0.96). Under nonlasing conditions, the thermal lens dioptric power experiences a roll-off, for which we propose an explanation based on the theory presented in Part I. These results are then used to yield the thermo-optic coefficient of the crystals. At last, we propose a simple analytical formulation useful for a rough estimation of the focal length.
Markers of inflammation are associated with clinical outcomes in patients with metastatic renal cell carcinoma treated with nivolumab (2015)

Meeting abstracts In previously treated patients with metastatic renal cell carcinoma (mRCC), the programmed death-1 (PD-1) inhibitor antibody nivolumab demonstrated objective response rates of 20%–22% and median overall survival (OS) of 18.2– 25.5 months[[1][1]]. An exploratory biomarker
A New Synthesis of Valienamine<sup>1</sup> (2001)

ADVERTISEMENT RETURN TO ISSUEPREVNoteNEXTA New Synthesis of Valienamine1Stanton H.-L. Kok, C. C. Lee, and Tony K. M. ShingView Author Information Department of Chemistry, The Chinese University of Hong Kong, Shatin, Hong Kong, China [email protected]Cite this: J. Org. Chem. 2001, 66, 21, 7184–7190Publication Date (Web):September 18, 2001Publication History Received21 February 2001Published online18 September 2001Published inissue 1 October 2001https://pubs.acs.org/doi/10.1021/jo010202thttps://doi.org/10.1021/jo010202tbrief-reportACS PublicationsCopyright © 2001 American Chemical SocietyRequest reuse permissionsArticle Views1068Altmetric-Citations34LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information SUBJECTS:Alcohols,Diols,Ethers,Hydrocarbons,Organic compounds Get e-Alerts
Multimedia in CSE Education (1997)

Large glucagon immunoreactive substances, extracted from the fetal bovine pancreas and separated by gel filtration in the presence of 6 M guanidinium-hydrochloride, were submitted to lectin-sepharose affinity column chromatograph. Gel-filtered peak I (approximately 45 K delta) and peak II (approximately 10 K delta) interacted biospecifically with concanavalin-A- and wheat-germ-lectin-sepharoses, suggesting glycoproteins as possible constituents of large glucagon immunoreactive substances in extracts of the fetal bovine pancreas. The glucagon-like immunochemical identity of the lectin-sepharose-bound substances was further substantiated by binding to antiglucagon antibodies-sepharose and by characteristic proportional dilutions in the glucagon radioimmunoassay.