gebhart/patrepeval huggingface dataset:
Fluorine Doping and Superconductivity of Nd<sub>2</sub>CuO<sub>4</sub> Thin Films (1990)

Fluorine was doped into sputter-deposited Nd 2 CuO 4 films to induce superconductivity in the films. The films annealed in the presence of NF 3 gas were observed to show remarkable resistivity change which was in parallel with the change of a -axis length. Fluorine incorporation in the films was verified by the X-ray photoelectron spectroscopy analysis. The specimen annealed at 800°C in 0.1 Torr NF 3 (1%)/Ar gas under UV light irradiation exhibited the onset of superconductivity at 27 K after a reducing procedure at 700°C in Ar.
¿Síndrome de Brugada, fenocopia de Brugada o solo intoxicación arritmogénica? (2020)

Las fracturas costales constituyen la lesion mas frecuente tras un traumatismo toracico cerrado no penetrante, aunque ocasionalmente pueden no ser diagnosticadas. La denervacion de la musculatura intercostal por lesion nerviosa tras una fractura costal, podria condicionar la aparicion de una pseudohernia en la pared toracica, siendo este fenomeno muy inusual. Presentamos un caso clinico de pseudohernia intercostal tras traumatismo toracico cerrado, no habiendo sido previamente descrito en la literatura un origen postraumatico. Aportamos la descripcion del cuadro clinico, y las imagenes mas representativas de la exploracion y las pruebas diagnosticas. Declaramos que este manuscrito no ha sido previamente publicado y no se encuentra en proceso de evaluacion por ninguna otra revista cientifica.
Microbial exposures in infancy predict levels of the immunoregulatory cytokine interleukin‐4 in filipino young adults (2012)

This study builds on a growing body of literature demonstrating that early ecological conditions have long-term effects on human biology by providing evidence that multiple proxies of microbial exposures in infancy are associated with adult IL-4.
Microbial diversity in homes and the risk of allergic rhinitis and inhalant atopy in two European birth cohorts (2021)

Our study suggests that a higher bacterial diversity may reduce the risk of allergic rhinitis later in childhood. The environment-dependent heterogeneity in the associations with inhalant atopy - visible here as inconsistent results between two differing cohorts - suggests that specific constituents of the diversity may be relevant.
Under the Hood: Understanding the Features of Mucin in Pseudomyxoma Peritonei (2023)

Pseudomyxoma peritonei (PMP) is a rare malignant growth characterized by the production of mucin and the potential for peritoneal relapse. This study aimed to investigate the immunohistochemical and biological characteristics of mucin in patients with cellular and acellular PMP. We prospectively analyzed mucin specimens obtained from our patient cohort and described the composition and type of mucin present in each sample. A metagenomic analysis of the samples was performed to investigate the bacterial composition of the PMP microbiome. Secreted mucins 2 and 5AC and membrane-associated mucin-1 were the primary components of mucin in both cellular and acellular tumor specimens. The metagenomic study revealed a predominance of the phylum Proteobacteria and the genus Pseudomonas. Notably, Pseudomonas plecoglossicida, a species not previously reported in the human microbiome, was found to be the most abundant organism in the mucin of pseudomyxoma peritonei. Our findings suggest that the presence of MUC-2 and mucin colonization by Pseudomonas is a characteristic feature of both cellular and acellular disease. These results may have significant implications for the diagnosis and treatment of this rare entity.
CLINICAL AND BIOLOGICAL EVALUATION OF THE NOVEL CD30/CD16A TETRAVALENT BISPECIFIC ANTIBODY (AFM13) IN RELAPSED OR REFRACTORY CD30‐POSITIVE LYMPHOMA WITH CUTANEOUS PRESENTATION: A BIOMARKER PHASE IB/IIA STUDY (NCT03192202) (2019)

Introduction: Natural Killer cells (NKC) play an important role in tumor immune-surveillance. AFM13 is a CD30/CD16A targeting high affinity bispecific tetravalent antibody that engages and activates NKC. This study evaluates AFM13 clinical and immunological activity. It examines the immunologic changes in the tumor and peripheral blood (PB) as a function of the dose and method of administration of AFM13 over time. Methods: Subjects with relapsed or refractory CD30 expressing lymphoma with cutaneous involvement were recruited into 3 cohorts: 1.5 mg/kg IV weekly, 7 mg/kg IV weekly and 7 mg/kg continuous intravenous infusion (CIVI) over 5 days weekly. Each cohort consisted of 3 patients. Subjects received 8 weeks of therapy each cycle. Response assessment was performed on week 11 of each cycle by mSWAT, photography, PET imaging and PB flow cytometry. A 2nd cycle was administered if there was no progression. Subjects underwent skin biopsies and PB immunologic studies as follows: pretreatment, day 5, week 4 and week 8 of therapy. Biopsies were analyzed and evaluated by a pathologist and IHC image analyzer. PB samples were analyzed by flow cytometry. Results: Nine subjects were accrued. Age 37-79 years, 3 of 9 where white and 6 of 9 were men. The median number of prior therapies was 4 (1-11) and 2 patients had progressed on brentuximab vedotin. The disease etiologies, treatment emergent toxicities and response by cohort are presented in table 1. An objective response rate of 44% was observed in the study. In the PB, flow cytometry revealed a decrease in circulating NKC (CD56+ CD3-, CD56+ CD16+ and NKp46+) during therapy with post therapy recovery. The activation marker CD69 on NKC increased in responders (R) compared to non-responders (NR). Similarly, tumor biopsies in R showed increased infiltration and activation of CD56+ NKC as opposed to NR (Figure 1). NKC cytotoxicity through the expression of Granzyme B was seen in R vs NR. Flow quantitation of circulating CD4+ CD25+ T cells (Tregs) shows a decrease in R vs. NR. Conclusions: AFM13 demonstrated a high ORR of 44 % among a population of heavily pretreated patients with a CD30 positive lymphoproliferative T-cell malignancy. AFM 13 exhibited activity post brentuximab vedotin failure. In addition, biological changes in NKC infiltration and activation in the PB and tissue biopsy correlate with response. This data is the first to demonstrate the therapeutic advantages of this bispecific, and the first to correlate changes in NKC as a function of dose and schedule. Rash (G4) Skin infection (G3) Skin infection (G3) IRR (G1) Keywords: anaplastic large cell lymphoma (ALCL); CD30; cutaneous T-cell lymphoma (CTCL).
A Concept-Based Integer Linear Programming Approach for Single-Document Summarization (2016)

Automatic single-document summarization is a process that receives a single input document and outputs a condensed version with only the most relevant information. This paper proposes an unsupervised concept-based approach for single-document summarization using Integer Linear Programming (ILP). Such an approach maximizes the coverage of the important concepts in the summary, avoiding redundancy, and taking into consideration some readability aspects of the generated summary as well. A new weighting method that combines both coverage and position of the sentences is proposed to estimate the importance of a concept. Moreover, a weighted distribution strategy that prioritizes sentences at the beginning of the document if they have relevant concepts is investigated. The readability of the generated summaries is improved by the inclusion of constraints into the ILP model to avoid dangling coreferences and breaks in the normal discourse flow of the document. Experimental results on the DUC 2001-2002 and the CNN corpora demonstrated that the proposed approach is competitive with state-of-the-art summarizers evaluated regarding the traditional ROUGE scores.
Preparation of Molecular Assemblies of Porphyrin-Linked Alkanethiol on Gold Surface and Their Redox Properties (1994)

Abstract Self-assembled monolayer of porphyrin-linked alkanethiol on gold surface was prepared and the structure was characterized on the basis of X-ray photoelectron spectroscopy (XPS), fluorescence spectra, and cyclic voltammetry (CV). Monolayer with zinc porphyrin chromophore was found to be electroactive in organic solvent.
Hypothyroidism Presenting As Anxiety Disorder (2019)

Anxiety disorder in hypothyroidism is relatively rare, as compared to depressive disorder. This case report discusses anxiety disorder in a 26 year old lady diagnosed with hypothyroidism. The anxiety symptoms were secondary to hypothyroidism, the underlying primary medical condition. General physical examination and examination of systems were within normal limits. There was no obvious thyroid enlargement. This case report is one of the few reports which discuss anxiety disorder in hypothyroidism.
NeuroViNE: A Neural Preprocessor for Your Virtual Network Embedding Algorithm (2018)

Network virtualization enables increasingly diverse network services to cohabit and share a given physical infrastructure and its resources, with the possibility to rely on different network architectures and protocols optimized towards specific requirements. In order to ensure a predictable performance despite shared resources, network virtualization requires a strict performance isolation and hence, resource reservations. Moreover, the creation of virtual networks should be fast and efficient. The underlying NP-hard algorithmic problem is known as the Virtual Network Embedding (VNE) problem and has been studied intensively over the last years. This paper presents NeuroViNE, a novel approach to speed up and improve a wide range of existing VNE algorithms: NeuroViNE is based on a search space reduction mechanism and preprocesses a problem instance by extracting relevant subgraphs, i.e., good combinations of substrate nodes and links. These subgraphs can then be fed to an existing algorithm for faster and more resource-efficient embeddings. NeuroViNE relies on a Hopfield network, and its performance benefits are investigated in simulations for random networks, real substrate networks, and data center networks.
The historical background to European Monetary Union (2001)

This highly topical book examines the development and future prospects for economic and monetary union in Europe. European Monetary Integration examines the background to economic and monetary union from a historical perspective that distinguishes between national and supranational currency areas, and an optimal currency area theory. The gradualist transition process is also considered.
Efficient microarea selection algorithm for infrastructure installation of broadband services (2016)

The diffusion of broadband services based on wired/wireless networks has been an important issue for a long time. Since the installation of such networks requires a large amount of time and money, low-usage facilities can cause problems for business in terms of investment efficiency. Therefore, the estimation of the potential demand for such networks in different areas, particularly microareas such as municipal areas across the nation, and the formulation of a microarea selection rule for the installation of the network infrastructure are absolutely necessary. In this paper, we propose a microarea selection algorithm that uses commuting flows among microareas as the broadband service propagation model. We have empirically and analytically evaluated the proposed algorithm, and the results have revealed that this method is very effective, particularly for the early stage of the infrastructure installation of broadband services.
Defining imaging biomarker cut points for brain aging and Alzheimer's disease (2016)

In the future, we will use a single cut point for amyloid PET (standardized uptake value ratio, 1.42; centiloid, 19) based on the reliable worsening cut point method. We will base lenient cut points for tau PET, FDG PET, and cortical thickness on the accuracy of cognitively impaired versus young CN method and base conservative cut points on the accuracy of cognitively impaired versus age-matched CN method.
Tamoxifen (TAM)-induced severe hot flashes (HF): Is dose reduction (DR) a safe and effective strategy? (2015)

557 Background: It is recognized that severe HF toxicity due to TAM can compromise compliance. We previously established that HF do not correlate with endoxifen level or CYP2D6genotype, though prior reports are varied on this subject. In this pilot study, we reduced TAM dose in patients with severe HF and determined whether HF were ameliorated whilst maintaining a purported therapeutic endoxifen level of > 15nM. Methods: Eighteen patients with severe HF on 20mg TAM were enrolled. CYP2D6genotype, trough level TAM and metabolites were measured. Loprinzi HF diaries were filled out before and after DR to 10mg TAM, and hot flash scores (HFS) derived. Other data collected included demographics, smoking and alcohol history, breast cancer history, previous chemotherapies, concurrent medications, menstrual history, body mass index (BMI) and other toxicities recognized to be associated with TAM. Results: At 20mg dose of TAM, baseline endoxifen levels were 24.5, 27.9, 0-91.9 nM (median, mean, range), consistent with the high variability seen in our previous 122 patient cohort. HFS at baseline were 108, 188, 4-1482 (median, mean, range). Upon dose reduction to 10mg, endoxifen levels fell to 13.2, 18.6, 0.6-71.9 nM (difference in means p = 0.056, two-tailed T test). HFS at 10mg fell to 38, 101, 5-864 (difference in means p = 0.36, two-tailed T test). Despite this lack of statistical significance, 78% of patients reported subjective improvement of hot flashes with DR. However after DR, the proportion of patients with an endoxifen level below a suggested therapeutic target of 15nM increased from 22% to 50%. HFS did not correlate with several patient characteristics including menopausal state, duration since last menstrual period and BMI (Spearman’s rank correlation coefficient). Conclusions: In this group of women selected for having significant HF, DR of TAM from 20mg to 10mg daily resulted in halving of endoxifen levels and subjective improvement of HF, however half were below a potential therapeutic level of endoxifen at the reduced dose. Therefore routine DR to ameliorate HF toxicity may not be safe unless therapeutic drug level monitoring is performed.
Silver-Inserted Heterojunction Photocatalysts for Z-Scheme Overall Pure-Water Splitting under Visible-Light Irradiation (2014)

Overall pure-water splitting under visible-light irradiation was accomplished utilizing a solid-state heterojunction photocatalyst following the Z-scheme mechanism. Zinc rhodium oxide (ZnRh2O4) and defective silver antimonate (Ag1–xSbO3–y) as hydrogen (H2)- and oxygen (O2)-evolution photocatalysts, respectively, were connected with silver (Ag) to prepare a solid-state Z-scheme photocatalysis system (ZnRh2O4/Ag/Ag1–xSbO3–y). In this system, Ag acted as a solid-state electron mediator for the transfer of electrons from the conduction band of Ag1–xSbO3–y to the valence band of ZnRh2O4. Utilizing the thus-constructed ZnRh2O4/Ag/Ag1–xSbO3–y photocatalyst, the simultaneous liberation of H2 and O2 from pure water at a molar ratio of ∼2:1 was achieved under irradiation with visible light at over 500 nm.
THE CONSEQUENCES OF EXCESS LEVELS OF HAEMOPOIETIC GROWTH FACTORS (1990)

The British Journal of Haematology publishes original research papers in clinical, laboratory and experimental haematology. The Journal also features annotations, reviews, short reports, images in haematology and Letters to the Editor.
Endoscopic and Endoscope-Assisted Neurosurgical Treatment of Suprasellar Arachnoidal Cysts (Mickey Mouse Cysts) (2005)

Suprasellar arachnoid cysts represent less than 10% of all intracranial arachnoid cysts. Some of them may be quiescent throughout life, some may become symptomatic as they become enlarged and some disappear spontaneously. In this study we discuss the surgical strategies for endoscopic and endoscope-assisted treatment of suprasellar (Mickey Mouse) cysts and analyze the clinical results and experience collected over some years in our department upon doing these operations routinely. Between December 1996 and December 2003, 13 patients (7 female and 6 male patients), mean age 29 years, underwent endoscopic or endoscope-assisted procedures for suprasellar cysts at our department. The indication for surgical treatment was based on the neurological and radiological examination. The goal of surgical treatment was to normalize the cerebrospinal fluid flow and to establish a communication, permanently, between the cyst cavity and the intraventricular or/and subarachnoid space. Intraoperatively we observed in all patients no complications. Seven of 13 patients, who had received shunt systems in other hospitals before admission in our clinic, remained shunt-free postoperatively. Overall clinical improvement was achieved for a long period of between 6 and 74 months in 11 patients, one developed a psychomotor disturbance and another one, who had epilepsy before treatment, was unchanged postoperatively. Our data suggest that suprasellar cysts are well treated by endoscopic or endoscope-assisted procedures with good clinical outcome and low surgical morbidity.
Improved technique for measuring mechanical deformations induced by an applied electric field to an organic insulator (2012)

International audience
Joint Noise and Reverberation Suppression for Speech Applications (2011)

An algorithm for joint suppression of noise and reverberation from speech signals is presented. The method requires a handclap recording that precedes speech activity. A running kurtosis technique is applied in order to extract an estimation of the late reflections of the room impulse response from the clap while a moving average filter is employed for the noise estimation. Moreover, the excitation signal derived from the Linear Prediction (LP) analysis of the noisy speech along with the estimated power spectrum of the late reflections are used to suppress late reverberation through spectral subtraction while a Wiener filter compensates for the ambient noise. A gain magnitude regularization step is also implemented to reduce overestimation errors. Objective and subjective results show that the proposed method achieves significant speech enhancement in all tested cases.
Optimization of a direct conversion multi-standard transmitter used for rescue operations (2016)

A new direct conversion architecture design of a multi-standard transmitter supporting cellular standards (GSM, UMTS and Wimax), wireless personal and local area network standards (Bluetooth, Zigbee and IEE802.11 b/g) as well as Radio navigation standards (GPS, Galileo) is presented in this paper dedicated for rescue applications. Behind this high number of standards, the proposed optimization design technique was introduced to reduce the cost, size and weight of the transmitter part.
The Relative Antioxidant Potencies of Some Polyphenols in Grapes and Wines (1997)

The antioxidant activities of some polyphenolic fractions of grapes and wines have been tested using in vitro and ex vivo tests. Polyphenolic fractions were obtained applying a liquid/liquid extraction method and analyzed by using HPLC/DAD, Ion Spray HPLC/MS and Electrospray MS. Some tannin/anthocyan interaction compounds were also extracted and analyzed from wines. EPR spectroscopy, TRAP assay, 2-deoxyribose assay and a platelet aggregation inhibition test were performed to test antioxidant activities of polyphenolic fractions. Results showed that the anthocyans fraction and the fraction containing procyanidins were very effective in antioxidant activity.
Optimisation de l'hydrodynamique dans des photobioréacteurs a haute productivité volumique pour éviter le développement de biofilm (2017)

International audience
A Characterization of Linkage-Based Clustering: An Extended Abstract (2010)

There are a wide variety of clustering algorithms that, when run on the same data, often produce very different clusterings. Yet there is no principled method to guide the selection of a clustering algorithm. The choice of an appropriate clustering is, of course, task dependent. As such, we must rely on domain knowledge. The challenge is to communicate such knowledge between the domain
pHH3 Immunostaining Improves Interobserver Agreement of Mitotic Index in Thin Melanomas (2011)

According to the seventh edition of the American Joint Committee on Cancer guidelines, the TNM staging category in thin cutaneous melanomas depends on the mitotic rate (MR). In this study, we analyze the interobserver agreement of the MR in a series of 92 thin cutaneous melanomas. Serial sections of the tumors were either stained with hematoxylin and eosin or immunohistochemically stained with pHH3, an antibody for phosphohistone H3, and analyzed by 4 observers. Determination of MR with pHH3 immunostaining resulted in higher sensitivity in counting mitosis for all observers. Moreover, interobserver agreement was higher with pHH3. Immunostaining with pHH3 is a sensitive method to detect mitosis in thin cutaneous melanomas, with good reproducibility of MR between independent observers. Further studies are needed to find out if higher sensitivity in the detection of mitosis by pHH3 immunostaining has additional prognostic relevance.
Parallel active cantilever AFM tool for high-throughput inspection and metrology (2019)

Atomic Force Microscopy (AFM) is a capable to provide high resolution CD-metrology and precise defects analysis on large wafers, masks or displays. However, AFM is not enough productive for high-throughput industrial uses. Standard single probe AFMs are showing low throughput as a serial imaging tools. The use of an array of four cantilevers as a Quattro-Array results in effective speed of 6 to 10 mm/s. An image size of 0.5mm x 0.2mm is achieved employing a piezoelectric positioner with a scan range of 200&mu;m x 200&mu;m and a resolution of 0.25nm (x,y) and 0.2nm (z), respectively. These capabilities are qualifying the Quattro-cantilever array system as fastest tool for. In this paper we present new results obtained with our Quattro-AFM high-throughput parallel SPM system that exhibits two key advances that are required for a successful deployment of SPM in time-efficient metrology, defect analysis and mask inspection.
Ripeness Evaluation of Post Harvest Fruits using Plant Bioelectric Potential (2018)

We proposed a novel technique for ripeness evaluation of post harvest fruits using plant bioelectric potential response which has been reported about a relationship with ambient environment conditions and physiological activities of plant. It is widely known that the ripeness of climacteric fruits improves after harvest. In this paper, we measured the bioelectric potential of climacteric fruits (pumpkins and apples) with the elapse of the days for evaluating the ripening stage of fruits. The results indicated that the bioelectric potential measurement has a possibility to evaluate the fruit ripeness.
Technical Opinion: deconstructing the “any” key (2000)

article Free Access Share on Technical Opinion: deconstructing the “any” key Authors: Munindar P. Singh North Carolina State Univ., Raleigh North Carolina State Univ., RaleighView Profile , Mona Singh Ericcson New Concepts, Research Triangle ParK, NC Ericcson New Concepts, Research Triangle ParK, NCView Profile Authors Info & Claims Communications of the ACMVolume 43Issue 4April 2000 pp 107–108https://doi.org/10.1145/332051.332081Online:01 April 2000Publication History 0citation519DownloadsMetricsTotal Citations0Total Downloads519Last 12 Months25Last 6 weeks3 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my Alerts New Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteView all FormatsPDF