gebhart/patrepeval huggingface dataset:
Implementable wireless access for B3G networks. I. MIMO mimo channel measurement, analysis, and modeling [Topics in Radio Communications] (2007)

Within Mobile VCE, a team of several leading U.K. universities, in dose association with major manufacturers and international telecom operators from the mobile industry, have been addressing the challenging task of designing transceiver structures for beyond 3G networks. Innovative approaches led to a plethora of cross-layer optimized technologies of low complexity and high robustness, allowing for the much promised multimedia-centric services over future wireless networks. This article presents a comprehensive overview of the research conducted within Mobile VCE's Core Wireless Access Research Programme, a key focus of which has naturally been on MIMO transceivers. The series of articles offers a coherent view of how the work was structured and comprises a compilation of material that has been presented in detail elsewhere (see references within the article). In this article, the first of four, MIMO channel measurements, analysis, and modeling are presented, which were then utilized to develop compact and distributed antenna arrays. Parallel activities led to research into low-complexity MIMO single-user space-time coding techniques, as well as SISO and MIMO multi-user CDMA-based transceivers for B3G systems. As well as feeding into the industry's in-house research program, significant extensions of this work are now in hand, within Mobile VCE's own core activity, aimed at securing major improvements in delivery efficiency in future wireless systems through cross-layer operation
Supplementary Table S4 from C/EBPα Confers Dependence to Fatty Acid Anabolic Pathways and Vulnerability to Lipid Oxidative Stress–Induced Ferroptosis in &lt;i&gt;FLT3&lt;/i&gt;-Mutant Leukemia (2023)

&lt;p&gt;Table S4: GSEA results in FLT3-ITD PDX AML cells ex vivo-treated with QUIZ or Veh.&lt;/p&gt;
Anti-inflammatory drug incorporation into polymeric nano-hybrids for local controlled release. (2008)

In this paper we present the formulation, preparation and characterization of new polymeric composite materials containing a nano-hybrid to be used for the controlled molecular delivery of an anti-inflammatory molecule, Diclofenac. The nano-hybrid consists of a layer of double hydroxide of an Mg-Al hydrotalcite type, in which we replaced the chloride anions present in the host galleries with Diclofenac anions by a simple ion-exchange reaction. Different amounts of the hybrid material were incorporated in polycaprolactone and processed as films of 0.15 mm thickness. The composite materials were analyzed by X-ray diffractometry, thermogravimetry and for their mechanical properties, and showed properties even better than those for the pristine polymer. The release process of the anti-inflammatory molecules was very interesting and promising for tuneable drug delivery. It consists of two stages: a first stage, very rapid as a burst in which a small fraction of the drug is released, and of a second stage that is much slower, extending for longer and longer periods. The parameters influencing the drug release were individuated and discussed.
Efficient NISI Compensation Technique for a Low-Cost Satellite Video Receiver (2013)

International audience
CESSNA (2018)

The introduction of computational resources at the network edge has moved us from a Client-Server model to a Client-Edge-Server model. By offloading computation from clients and/or servers, this approach can reduce response latency, backbone bandwidth, and computational requirements on clients. While this is an attractive paradigm for many applications, particularly 5G mobile networks and IoT devices, it raises the question of how one can design such a client-edge-server system to tolerate edge failures and client mobility. The key challenge is to ensure correctness when the edge processing is stateful (so the processing depends on state it has previously seen from the client and/or server). In this paper we propose an initial design for meeting this challenge called Client-Edge-Server for Stateful Network Applications (CESSNA).
Multivariate analysis of the insulin resistance syndrome in women. (1994)

The insulin resistance syndrome (IRS) is characterized by a constellation of interrelated coronary heart disease (CHD) risk factors, including dyslipidemia, obesity, central obesity, elevated systolic blood pressure, and hyperinsulinemia. Factor analysis was used to investigate the clustering of these risk factors in individuals by examining the correlational structure among these variables. Data from 281 genetically unrelated nondiabetic women who participated in exam 2 (1979 to 1980) of the Kaiser Permanente Women Twins Study were used. Factor analysis reduced 10 correlated risk factors to 3 uncorrelated factors, each reflecting a different aspect of the IRS: factor 1 (increased body weight, waist circumference, fasting insulin, and glucose), factor 2 (increased postload and fasting glucose and insulin and systolic blood pressure), and factor 3 (larger low-density lipoprotein particles, decreased plasma triglycerides, and increased high-density lipoprotein). Together, the factors explained nearly 66% of the total variance in the data. Thus, factor analysis defined three distinct aspects of the IRS in this sample of nondiabetic women. These factors may reflect separate underlying mechanisms of the syndrome, each of which may also be involved in CHD risk.
Targeting different pulsing regimes in tm fiber laser with a nonlinear amplifying loop mirror (2015)

Targeting different pulsing regimes in Tm fiber laser with a nonlinear amplifying loop mirror
Reduction of substrate-mode effects in power-combining arrays (2001)

We report a simple theory for the reduction of substrate modes in quasi-optical power-combining arrays. This qualitative theory predicts that detrimental substrate-mode effects can be greatly reduced through a judicious choice of the array unit cell size. Experimental evidence from quasi-optical tripler grids is presented to confirm the theory. Measured results show a dramatic improvement in the radiation pattern and effective radiated power of arrays with both grounded and ungrounded substrates.
Lysosomal vesiculophagy terminates STING signalling (2022)

Stimulator of interferon genes (STING) is essential for the type I interferon response against a variety of DNA pathogens 1,2 . Upon emergence of cytosolic DNA, STING translocates from the endoplasmic reticulum (ER) to the Golgi where STING activates the downstream kinase TBK1, then to lysosome through recycling endosomes (REs) for its degradation 3–6 . Although the molecular machinery of STING activation is extensively studied and defined 7 , the one underlying STING degradation has not yet been fully elucidated. Here we show an unanticipated mechanism termed “lysosomal vesiculophagy” dictates STING degradation. Airyscan super-resolution microscopy and correlative light/electron microscopy show that a cluster of STING-positive vesicles of an RE origin are directly encapsulated into lysosome. Screening of mammalian Vps genes, the yeast homologues of which regulate Golgi-to-vacuole transport 8 , shows that the endosomal sorting complexes required for transport (ESCRT) is essential for the STING encapsulation into lysosome. Knockdown of Tsg101 and Vps4, components of ESCRT 9 , results in the accumulation of STING vesicles in the cytosol, leading to the sustained type I interferon response. STING undergoes ubiquitination at REs and degradation of STING requires the ubiquitin-binding domain of Tsg101, ensuring the selective degradation of activated STING. Our results reveal a novel mode of autophagy that prevents hyperactivation of innate immune signalling and provide insights into the ER-Golgi-REs-lysosomes pathway for degradation of transmembrane proteins.
Learning styles and learning strategies in university students (2010)

Se estudia la relacion entre los estilos y las estrategias de aprendizaje y el rol del sexo en una muestra de estudiantes que ingresa a la universidad, cuyo rango de edad es de 17 a 21 anos. Se explican las teorias y conceptos respecto de los instrumentos de medicion utilizados. Se analizan los resultados obtenidos y los estadisticos correspondientes de la aplicacion de los cuestionarios usados en la muestra. Los resultados tienen implicaciones educativas, y revelan diferencias por sexo en relacion al modo de procesar y transformar la informacion.
Unusual current‐voltage characteristics of single crystalline and bicrystalline La<sub>0.7</sub>Ca<sub>0.3</sub>MnO<sub>3</sub> films (2004)

Abstract The current‐voltage characteristics of single crystalline and bicrystalline La 0.7 Ca 0.3 MnO 3 films were measured and analyzed. Several epitaxial films, as well as 45° [001]‐tilt grain boundaries, display current‐voltage characteristics which are asymmetric with respect to polarity reversal of the bias current. One epitaxial film has a polarity dependent resistance of ∼340kΩ and of ∼670kΩ in forward and in reverse direction, respectively.
Characterization of freezing of gait subtypes and the response of each to levodopa in Parkinson's disease (2003)

To assess the effect of levodopa on distinct freezing of gait (FOG) subtypes in patients with 'off' FOG. Nineteen patients (12 men, mean age 62.0 +/- 8.4 years) with Parkinson's disease and clinically significant FOG during 'off' states were videotaped whilst walking 130 m during 'off' and 'on' states. Three independent observers characterized the type, duration, and clinical manifestations and quantified FOG by analyzing the videotapes. Their combined mean scores were used for statistical analysis. The intra-class correlation coefficient assessed inter-observer reliability. Wilcoxon and Friedman tests evaluated differences in mean frequencies of FOG characteristics. During 'off' states, FOG was elicited by turns (63%), starts (23%), walking through narrow spaces (12%) and reaching destinations (9%). These respective values were only 14, 4, 2 and 1% during 'on' states (P < 0.011). Moving forward with very small steps and leg trembling in place were the most common manifestations of FOG; total akinesia was rare. Most FOG episodes took <10 s and tended to be shorter during 'on' states. Levodopa significantly decreased FOG frequency (P < 0.0001) and the number of episodes with akinesia (P < 0.001). Distinction amongst FOG subtypes enables evaluation of distinctive therapeutic response. Levodopa helps in reducing the frequency and duration of 'off'-related FOG.
Musculoskeletal involvement in cystic echinococcosis: report of eight cases and review of the literature. (1997)

Patients with musculoskeletal lesions of cystic echinococcosis typically have cystic structures in adjacent soft tissues. These cysts morphologically resemble abscesses, with peripheral uptake of contrast medium and variable signal intensities on T1-weighted MR images. The absence of calcifications or endovesicular daughter cysts does not exclude the diagnosis of cystic echinococcosis.
Computational Art Inspired by Genome Browsers (2019)

Abstract This article describes the genome browser of the plant Arabidopsis thaliana as an inspiration for the creation of geometric artworks developed with code. Genome browsers are bioinformatic tools that life scientists use to access and visualize genome sequence data from species of interest. The artworks presented are inspired by genome sequence data and provide aesthetic interpretations of genes and their genomic contexts by an individual artist alternatively to the conventional scientific visualization of genome data.
What Is the Frequency of Vascular Injury After Knee Dislocation? (2014)

Level IV, prognostic study. See Instructions for Authors for a complete description of levels of evidence.
How uncertainty consumes prediction (2005)

The problem of prediction of target location and the role that this problem plays in the design and evolution of a modern combat system is analyzed. Connected with this problem is the task of choosing one set of hypotheses from among many viable sets. The functional dependence of the ability to make a prediction is discussed with particular attention paid to efficiencies and deficiencies. A general principle is proposed that helps bound the prediction problem from a weapons system perspective. A technique due to Jaynes called the transformation group method is applied to understand some of the problems of prediction
Pushouts in software architecture design (2012)

A classical approach to program derivation is to progressively extend a simple specification and then incrementally refine it to an implementation. We claim this approach is hard or impractical when reverse engineering legacy software architectures. We present a case study that shows optimizations and pushouts ---in addition to refinements and extensions---are essential for practical stepwise development of complex software architectures.
Cytotoxicity of the matrix metalloproteinase–activated anthrax lethal toxin is dependent on gelatinase expression and B-RAF status in human melanoma cells (2008)

Anthrax lethal toxin (LeTx) shows potent mitogen-activated protein kinase pathway inhibition and apoptosis in melanoma cells that harbor the activating V600E B-RAF mutation. LeTx is composed of two proteins, protective antigen and lethal factor. Uptake of the toxin into cells is dependent on proteolytic activation of protective antigen by the ubiquitously expressed furin or furin-like proteases. To circumvent nonspecific LeTx activation, a substrate preferably cleaved by gelatinases was substituted for the furin LeTx activation site. Here, we have shown that the toxicity of this matrix metalloproteinase (MMP)-activated LeTx is dependent on host cell surface MMP-2 and MMP-9 activity as well as the presence of the activating V600E B-RAF mutation, making this toxin dual specific. This additional layer of tumor cell specificity would potentially decrease systemic toxicity from the reduction of nonspecific toxin activation while retaining antitumor efficacy in patients with V600E B-RAF melanomas. Moreover, our results indicate that cell surface-associated gelatinase expression can be used to predict sensitivity among V600E B-RAF melanomas. This finding will aid in the better selection of patients that will potentially respond to MMP-activated LeTx therapy.
Humidity and Temperature Control in the ASTROCULTURE™ Flight Experiment (1994)

&lt;div class="htmlview paragraph"&gt;The ASTROCULTURE™ (ASC) middeck flight experiment series was developed to test subsystems required to grow plants in reduced gravity, with the goal of developing a plant growth unit suitable for conducting quality biological research in microgravity. Previous Space Shuttle flights (STS-50 and STS-57) have successfully demonstrated the ability to control water movement through a particulate rooting matrix in microgravity and the ability of LED lighting systems to provide high levels of irradiance without excessive heat build-up in microgravity.&lt;/div&gt; &lt;div class="htmlview paragraph"&gt;The humidity and temperature control system used in the middeck flight unit is described in this paper. The system controls air flow and provides dehumidification, humidification, and condensate recovery for a plant growth chamber volume of 1450 cm&lt;sup&gt;3&lt;/sup&gt;. It provides the ASC flight units with a level of environmental control equivalent to most terrestrial plant growth chambers and has been shown to be capable of controlling humidity levels in the chamber to within 5% relative humidity over a range of 50% to 90% RH and air temperature levels in the chamber within 2°C. However, in this prototype unit, control is limited to the range of 24°C to 35°C. A prototype system was tested with no plants on STS-60, and a flight unit is currently scheduled to be tested on STS-63 in which the first experiments with plants will be conducted.&lt;/div&gt;
A Minimal Model for Secure Computation (2002)

We consider a minimal scenario for secure computation: Parties A and B have private inputs x and y and a shared random string r. A and B are each allowed to send a single message to a third party C, from which C is to learn the value of f(x, y) for some function f, but nothing else. We show that this model is surprisingly powerful: every function f can be securely computed in this fashion. If the messages are required to be of polynomial size, then we exhibit an efficient protocol for any function f computable in nondeterministic logspace. Using a computational notion of security, we exhibit efficient protocols for any polynomial-time computable function f, assuming the existence of one-way functions. The above results generalize to the case where there are more than two parties with private inputs. The minimalistic nature of our model makes it easy to transform positive results achieved in our model to other more general models of secure computation. It also gives hope for lowerbound proofs. We give an alternative characterization of our model in terms of graph embeddings, and use this to show that for most Boolean functions on {0, 1} n × {0, 1} n, the need to hide just one of the input bits from C requires a communication overhead of n bits. 1
Investigation of reticle defect formation at DUV lithography (2002)

Defect formation on advanced photomasks used for DUV lithography has introduced new challenges at low k<sub>1</sub> processes industry wide. Especially at 193-nm scanner exposure, the mask pattern surface, pellicle film and the enclosed space between the pellicle and pattern surface can create a highly reactive environment. This environment can become susceptible to defect growth during repetitive exposure of a mask on DUV lithography systems due to the flow of high energy through the mask. Due to increased number of fields on the wafer, a reticle used at a 300-mm wafer fab receives roughly double the number of exposures without any cool down period, as compared to the reticles in a 200-mm wafer fab. Therefore, 193-nm lithography processes at a 300-mm wafer fab put lithographers and defect engineers into an area of untested mask behavior. During the scope of this investigation, an attenuated phase shift mask (attPSM) was periodically exposed on a 193-nm scanner and the relationship between the number of exposures (i.e., energy passed through the mask during exposures) versus defect growth was developed. Finally, chemical analysis of these defects was performed in order to understand the mechanism of this “growth”.
Computational Methods in the Developing of a Knowledge-Based System for the Prediction of Solid Catalyst Performance (2007)

International audience
Additive Manufacturing of Wind Turbine Molds (2017)

The objective of this project was to explore the utility of Big Area Additive Manufacturing (BAAM) for low cost manufacturing of wind turbine molds. Engineers at Oak Ridge National Laboratory (ORNL) and TPI Composites (TPI) collaborated to design and manufacture a printed mold that can be used for resin infusion of wind turbine components. Specific focus was on required material properties (operating temperatures and pressures, coefficient of thermal expansion (CTE), thermal conductivity), surface finish (accuracy and coatings) and system integration (integrated vacuum ports, and heating element). The project began with a simple proof of principle components, targeting surface coatings and material properties for printing a small section (approximately 4’ x 4’ x 2’) of a mold. Next, the second phase scaled up and integrated with the objective of capturing all of the necessary components (integrated heating to accelerate cure time, and vacuum, sealing) for resin infusion on a mold of significant size (8’ x 20’ x 6’).
Tb3+-Yb3+ cooperative down and up conversion processes in Tb0.81Ca0.19F2.81:Yb3+ single crystals (2011)

The energy transfer processes between Tb3+ and Yb3+ ions are studied in Tb-based fluoride single crystals. These are very transparent from the UV to the IR wavelength regions, except for the characteristic absorption lines of the rare-earth ions under study. In contrast with previously reported Tb3+-doped glasses and oxide powders, these crystals containing a high Tb3+ concentration present two major advantages for the study of the energy transfer processes in the Tb3+-Yb3+ ion pair. Firstly, the adverse influence of host defects is minimized with the use of high quality crystals. Secondly, the high Tb3+ concentration guarantees a much higher absorption cross-section of UV light, and consequently these crystals have real potential for practical applications. Photoluminescence spectra in the visible-IR wavelength region demonstrate the existence of efficient down and up conversion processes by crossed excitation and emission characteristics of Tb3+ and Yb3+ ions. In the down conversion process, Tb3+(5D4) → 2Yb3+(2F5/2), two IR photons are emitted for each Tb3+ ion deexcited by second-order energy transfer to two Yb3+ ions. The total quantum efficiency of the down conversion process in the fluoride system is shown to increase linearly with the Yb3+ concentration, reaching its maximum at the Yb3+ solubility limit in the fluoride host. Further, efficient up conversion by two- and three-IR photon absorption is observed.
Layered HfSiON-based tunnel stacks for voltage reduction and improved reliability in TANOS memories (2010)

In this work we present the integration of Band Engineered TANOS-like memories using HfSiON in the tunnel stack to boost the programming efficiency and improve cycling. An accurate correlation analysis between the gate-stack material physical properties and the memory performances is presented. In particular, the importance of the nitridation step of HfSiON on the memory retention characteristics at high temperature is suggested.
Inflammatory response to liver fluke Opisthorchis viverrini in mice depends on host master coregulator MTA1, a marker for parasite-induced cholangiocarcinoma in humans (2011)

These findings suggest that MTA1 status plays an important role in conferring an optimal cytokine response in mice following infection with O. viverrini and is a major player in parasite-induced CCA in humans.
Paracrine Effect of Bone Marrow Cells on Hypoxia‐Mediated Vascular Growth (2006)

We have previously demonstrated a population of bone marrow derived cells (BMCs) within mouse skeletal muscle, which reside in a perivascular position and if mobilized by granulocyte‐macrophage colony stimulating factor (GM‐CSF) are capable of augmenting capillary growth without transdifferentiation into endothelial cells. In this study we expanded the scope of our inquiry to also determine the effect of BMCs on collateral vessel growth. While arcade arteriole length within the mouse spinotrapezius muscle was unchanged after 3 weeks of hypoxia (0 2 =10%), GM‐CSF treatment concurrent with the first week of hypoxia resulted in a 22% increase in arcade arteriole length per muscle. This increase coincided with a doubling in the number of round BMCs associated with terminal arterioles. In addition we determined that the largest subset of muscle‐resident BMCs from the muscle tissue stained CD11b+ by flow cytometry, indicating myeloid lineage. After stimulation with hypoxia, muscle‐resident CD11b+ BMCs contained significantly higher intracellular levels of VEGF, matrix metalloproteinase‐9, and PDGF. Finally, mice transplanted with bone marrow deficient in CD18, used for adhesion and emigration by circulating cells, displayed a trend (p = .16) toward decreased hypoxia‐mediated angiogenesis associated with diminished recruitment of BMCs to the muscle tissue. These observations further support our hypothesis of a paracrine role for BMCs during physiologic angiogenesis. Supported by NIH HL65958 and 5T32 HL007284