gebhart/patrepeval huggingface dataset:
Is ‘scarless wound healing’ applicable to glaucoma surgery? (2007)

The ‘simple’ problem of fibrosis has a diverse public health impact ranging from disfiguring scarring, fibrosis of organs, visceral adhesions, mobility restriction and blindness. Both lay people and clinicians clearly recognize the phenotypic variation of cutaneous surgical outcomes ranging from keloids, hypertrophic scars, ‘normal’ scar formation and ‘scarless’ wound healing. By comparing the three major wound healing processes of inflammation, angiogenesis and fibrosis in the fetal and postnatal periods, clear differences are apparent in all three of these wound healing processes. The purpose of this review is to examine the current understanding of scarless wound healing and then to provide a perspective on the potential future application of these concepts to improve glaucoma filtration surgery outcomes.
The normal modes at the surface of simple metals (1991)

The dynamic response of the electrons at the surface of simple metals, like Na, K and Cs, to an external time varying field is discussed in this paper. Of special interest are the normal modes at a surface, defined theoretically by the poles in the reflection function. The surface plasmon is the best known normal mode of the electrons at the surface, but theory has predicted other normal modes. Recently a new mode, called a Multipole Plasmon Mode, has been observed in inelastic electron scattering experiments. The origin and physical properties of this Multipole Mode as well as the Surface Plasmon Mode will be described.
ChemInform Abstract: BIS ADDUCTS OF PHTHALOCYANINATOIRON(II) WITH GROUP 6A AXIAL DONOR ATOMS. CRYSTAL AND MOLECULAR STRUCTURE OF SULFUR‐BONDED BIS(DIMETHYL SULFOXIDE)PHTHALOCYANINATOIRON(II)‐DIMETHYL SULFOXIDE (1/2) (1981)

Abstract Phthalocyaninato‐Fe(II) bildet in DMSO oder Tetrahydrothiophen bei Temp. von 1 lO‐1 15°C die als Disolvate isolierten 1:2‐Adduk‐ te (I), die IR‐spektroskopisch charakterisiert werden.
Neuronal cells loaded with PEI-coated Fe3O4 nanoparticles for magnetically guided nerve regeneration (2013)

We report a one-step synthesis protocol for obtaining polymer-coated magnetic nanoparticles (MNPs) engineered for uploading neural cells. Polyethyleneimine-coated Fe<sub>3</sub>O<sub>4</sub> nanoparticles (PEI-MNPs) with sizes of 25 ± 5 nm were prepared by oxidation of Fe(OH)<sub>2</sub> by nitrate in basic aqueous media and adding PEI in situ during synthesis. The obtained PEI-MNP cores displayed a neat octahedral morphology and high crystallinity. The resulting nanoparticles were coated with a thin polymer layer of about 0.7-0.9 nm, and displayed a saturation magnetization value M<sub>S</sub> = 58 A m<sup>2</sup> kg<sup>-1</sup> at 250 K (64 A m<sup>2</sup> kg<sup>-1</sup> for T = 10 K). Cell uptake experiments on a neuroblastoma-derived SH-SY5Y cell line were undertaken over a wide time and MNP concentration range. The results showed a small decrease in cell viability for 24 h incubation (down to 70% viability for 100 μg ml<sup>-1</sup>), increasing the toxic effects with incubation time (30% cell survival at 100 μg ml<sup>-1</sup> for 7 days of incubation). On the other hand, primary neuronal cells displayed higher sensitivity to PEI-MNPs, with a cell viability reduction of 44% of the control cells after 3 days of incubation with 50 μg ml<sup>-1</sup>. The amount of PEI-MNPs uploaded by SH-SY5Y cells was found to have a linear dependence on concentration. The intracellular distribution of the PEI-MNPs analyzed at the single-cell level by the dual-beam (FIB/SEM) technique revealed the coexistence of both fully incorporated PEI-MNPs and partially internalized PEI-MNP-clusters crossing the cell membrane. The resulting MNP-cluster distributions open the possibility of using these PEI-MNPs for magnetically driven axonal re-growth in neural cells.
High-Frequency EPR Study of a New Mononuclear Manganese(III) Complex:  [(terpy)Mn(N<sub>3</sub>)<sub>3</sub>] (terpy = 2,2‘:6‘,2‘ ‘-Terpyridine) (2001)

The isolation and structural characterization of [(terpy)Mn(III)(N3)3], complex 1, is reported (terpy = 2,2':6',2' '-terpyridine). Complex 1, a product of the reaction between the mixed-valence dimer [(terpy)(H2O)Mn(III)(O)2Mn(IV)(OH2)(terpy)](NO3)3 and NaN3, crystallizes in a triclinic system, space group P1, a = 8.480(1) A, b = 8.9007(2) A, c = 12.109(2) A, alpha = 93.79(1) degrees, beta = 103.17(1) degrees, gamma = 103.11(1) degrees, and Z = 2. Complex 1 exhibits a Jahn-Teller distortion of the octahedron characteristic of a six-coordinated high-spin Mn(III). A vibrational spectroscopic study was performed. The nu(asym)(N3) mode of complex 1 appears in the IR as a strong band at 2035 cm(-1) with a less intense feature at 2072 cm(-1), and in the FT-Raman as a strong band at 2071 cm(-1) with a weaker broad band at 2046 cm(-1). The electronic properties of complex 1 were investigated using a high-field and high-frequency EPR study (190-475 GHz). The different spin Hamiltonian parameters have been determined (D = -3.29 (+/-0.01) cm(-1), E = 0.48 (+/-0.01) cm(-1), E '= 0.53 (+/-0.01) cm(-1), g(x) = 2.00 (+/-0.005), g(y) = 1.98 (+/-0.005), g(z) = 2.01 (+/-0.005)). These parameters are in agreement with the geometry of complex 1 observed in the crystal structure, a D < 0 related to the elongated distortion, and a value of E/D close to 0.2 as expected from the highly distorted octahedron. The two values of the E-parameter are explained by the presence of two slightly different structural forms of complex 1 in the crystal lattice. A second hypothesis was explored to explain the experimental data. The calculation for the simulation was done taking into account that the g and D tensors are not collinear due to the low symmetry of complex 1. In that case, the spin Hamiltonian parameters found are D = -3.29 (+/-0.01) cm(-1), E = 0.51 (+/-0.01) cm(-1), g(x) = 2.00 (+/-0.005), g(y) = 1.98 (+/-0.005), and g(z) = 2.01 (+/-0.005).
Titelbild: Heterochromia in Designed Metallopeptides: Geometry‐Selective Binding of Cd<sup>II</sup> in a De Novo Peptide (Angew. Chem. 35/2007) (2007)

Heterochromie bezeichnet die genetisch bedingte Verschiedenfarbigkeit der Augen mancher Individuen. Analog unterscheiden sich die physikalischen Eigenschaften nahezu identischer Metallbindungsstellen in heterochromen Peptiden, für die V. L. Pecoraro et al. in ihrer Zuschrift auf S. 6808 ff. ein Beispiel vorstellen, nach der Metallbindung. Das Titelbild zeigt ein de novo entworfenes heterochromes Peptid, das zwei CdII-Ionen in unterschiedlichen Koordinationsgeometrien bindet.
X-ray absorption and x-ray magnetic circular dichroism studies on a monatomic bcc-Co(001) layer facing an amorphous Al–O tunnel barrier (2006)

We studied the electronic states and magnetic moments of a bcc-Co(001) monatomic layer facing an amorphous Al–O tunneling barrier using x-ray absorption spectroscopy (XAS) and x-ray magnetic circular dichroism (XMCD) at the L2,3 core edges of Co. Both the XAS and XMCD measurements revealed that 1 monolayer (ML) Co is not oxidized. The magnetic moment of 1 ML bcc Co(001) facing the amorphous Al–O was observed to be almost the same as that of bulk Co. In contrast, the total magnetic moment of 1 ML bcc Co(001) facing a metallic Al layer was reduced by the effect of the proximity to Al atoms.
A New Boranophosphorylation Reaction for the Synthesis of Deoxyribonucleoside Boranophosphates. (2002)

Abstract For Abstract see ChemInform Abstract in Full Text.
High Sensitivity Pressure Measurements Using Side-Hole Fibre (1997)

Get PDF Email Share Share with Facebook Tweet This Post on reddit Share with LinkedIn Add to CiteULike Add to Mendeley Add to BibSonomy Get Citation Copy Citation Text J. A. Croucher, L. Gomez-Rojas, S. Kanellopoulos, and V. A. Handerek, "High Sensitivity Pressure Measurements Using Side-Hole Fibre," in 12th International Conference on Optical Fiber Sensors, Vol. 16 of 1997 OSA Technical Digest Series (Optica Publishing Group, 1997), paper OTuD2. Export Citation BibTex Endnote (RIS) HTML Plain Text Citation alert Save article
Obsessive‐compulsive disorder in patients with velocardiofacial (22q11 deletion) syndrome (2003)

The study of neurogenetic microdeletion syndromes provides an insight into the developmental psychopathology of psychiatric disorders. The aim of the study was to evaluate the prevalence of psychiatric disorders, especially obsessive-compulsive disorder (OCD), in patients with velocardiofacial syndrome (VCFS), a 22q11 microdeletion syndrome. Forty-three subjects with VCFS of mean age 18.3 +/- 10.6 years were comprehensively assessed using semi-structured psychiatric interview and the Yale-Brown obsessive compulsive scale (Y-BOCS). Best estimate diagnoses were made on the basis of information gathered from subjects, parents, teachers, and social workers. Fourteen VCFS subjects (32.6%) met the DSM-IV criteria for OCD. OCD had an early age of onset and generally responded to fluoxetine treatment. It was not related to mental retardation. The most common obsessive-compulsive symptoms were contamination, aggression, somatic worries, hoarding, repetitive questions, and cleaning. Sixteen of the 43 patients (37.2%) had attention-deficit/hyperactivity disorder (ADHD), and 7 (16.2%) had psychotic disorder. The results of our study suggest that there is a strong association between VCFS and early-onset OCD. This finding may be significant in the understanding of the underlying genetic basis of OCD.
Design challenges regarding high-definition electro-optic/infrared stabilized imaging systems (2013)

Today, requirements for imaging systems are shifting from standard definition to high-definition (HD) imaging systems. Along with HD imagers, users are also requiring embedded metadata and high precision pointing. These requirements place new demands on the opto-mechanical, thermal, and electrical subsystems of stabilized platforms that use these imagers. This paper discusses the impact of HD imagers on gimbal design, including requirements for better stabilization, better thermal management, and better electronics to handle the high data rates associated with HD imagers. We also discuss how the requirements for wide area surveillance sensors will further impact the gimbal designs for these sensors.
Tomoxetine and the stereoselectivity of drug action (1987)

Abstract The phenoxypropylamine derivative tomoxetine has been shown to inhibit noradrenaline (NA) uptake into synaptosomes from rat hypothalamus (Wong et al 1982). Differences in the potencies of the resolved optical isomers, (-)-tomoxetine (I) and (+)-tomoxetine were also noted, the (-)-isomer being more potent than the racemate or the (+)-isomer in-vitro and in-vivo.
Hierarchical caching and prefetching for continuous media servers with smart disks (2000)

To avoid the throughput limitations of traditional data retrieval algorithms, the authors have developed a family of algorithms that exploit emerging smart-disk technologies and increase data throughput on high-performance continuous media servers.
Corrigendum to “Complete pathological response following levonorgestrel intrauterine device in clinically stage 1 endometrial adenocarcinoma: Results of a randomized clinical trial” [Gynecologic Oncology 161 (2021) 143–151] (2021)

The authors regret that Donal Brennan was missing from the author list. The details shown above are now correct with Dr Brennan included. Dr. Brennan contributed to conceptualisation and data curation and final review of manuscript. Dr. Brennan does not have any conflicts to disclose. The authors would like to apologise for any inconvenience caused. Complete pathological response following levonorgestrel intrauterine device in clinically stage 1 endometrial adenocarcinoma: Results of a randomized clinical trialGynecologic OncologyVol. 161Issue 1PreviewIntrauterine levonorgestrel (LNG-IUD) is used to treat patients with endometrial adenocarcinoma (EAC) and endometrial hyperplasia with atypia (EHA) but limited evidence is available on its effectiveness. The study determined the extent to which LNG-IUD with or without metformin (M) or weight loss (WL) achieves a pathological complete response (pCR) in patients with EAC or EHA. Full-Text PDF Open Access
Interleukin-4 inhibits growth of multiple myelomas by suppressing interleukin-6 expression (1991)

Unfractionated bone marrow (BM) cells obtained from patients with multiple myeloma (MM) exhibit high levels of interleukin (IL)-6. Secretion of IL-6 by these cells as well as spontaneous plasma cell proliferation can be abrogated by neutralizing anti-IL-6 monoclonal antibody (MoAb). Treatment of BM cells with recombinant human (rh)IL-4 at doses of 50 to 250 U/mL blocked endogenous IL-6 synthesis in a dose- dependent fashion and was associated with significant reduction of plasma cell growth that could be reversed by exogenous rhIL-6. Enrichment of BM cells from MM patients for plasma cells and adherent cells and analysis of IL-6 mRNA in these subpopulations by means of quantitative polymerase chain reaction (PCR) showed that adherent BM cells accounted for most of the synthesis of IL-6 transcripts, whereas plasma cells displayed negligible levels of IL-6 mRNA only. These results suggest therapeutic evaluation of rhIL-4 in patients with plasma cell neoplasms.
Class AB power amplifier advanced design techniques (2002)

Relevant existing design procedures for microwave class-AB power amplifiers are briefly reviewed and discussed, focusing on their field of application and relative strength or drawbacks. Both simplified and accurate nonlinear methodologies are addressed.
The Development of Perpendicular Magnetic Recording Tape By Roll-to-Roll In-Line Sputtering (2014)

A method was developed that was capable of producing a 1000 m length of sputter-deposited magnetic tape using a roll-to-roll in-line sputtering system. This method produced a magnetic recording structure having perpendicular magnetic orientation and uniform grain size, which was observed over the full length of the sputtered area. The potential read/write performance of 60 Gb/in <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> areal density and good durability were also observed. Therefore, the possibility of utilizing sputter-deposited tape production for high recording density media was evident.
Vasectomy: AUA Guideline (2012)

Vasectomy should be considered for permanent contraception much more frequently than is the current practice in the U.S. and many other nations. The full text of this guideline is available to the public at http://www.auanet.org/content/media/vasectomy.pdf.
High-pressure Brillouin scattering of amorphous BeH2 (2005)

High-pressure micro-Brillouin scattering is employed to investigate the pressure dependence of the sound velocity, refractive index, equation of state, and mechanical properties of amorphous BeH2. The refractive index n has been determined by using two scattering geometries (70 degrees and 180 degrees). The equation of state is deduced from the pressure dependences of the sound velocity. The bulk modulus is 14.2 (+/-3.0) GPa and its pressure derivative is 5.3 (+/-0.5). The polarizability is calculated from the refractive index and the density of the material. It increases with pressure while Poisson's ratio decreases with pressure.
Physical developmental cues for the maturation of human pluripotent stem cell-derived cardiomyocytes (2014)

Human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) are the most promising source of cardiomyocytes (CMs) for experimental and clinical applications, but their use is largely limited by a structurally and functionally immature phenotype that most closely resembles embryonic or fetal heart cells. The application of physical stimuli to influence hPSC-CMs through mechanical and bioelectrical transduction offers a powerful strategy for promoting more developmentally mature CMs. Here we summarize the major events associated with in vivo heart maturation and structural development. We then review the developmental state of in vitro derived hPSC-CMs, while focusing on physical (electrical and mechanical) stimuli and contributory (metabolic and hypertrophic) factors that are actively involved in structural and functional adaptations of hPSC-CMs. Finally, we highlight areas for possible future investigation that should provide a better understanding of how physical stimuli may promote in vitro development and lead to mechanistic insights. Advances in the use of physical stimuli to promote developmental maturation will be required to overcome current limitations and significantly advance research of hPSC-CMs for cardiac disease modeling, in vitro drug screening, cardiotoxicity analysis and therapeutic applications.
Characterizing the contribution of voltage- and calcium-dependent coupling to action potential stability: implications for repolarization alternans (2007)

Experiments have provided suggestive but inconclusive insights into the relative contributions of transmembrane voltage and intracellular calcium handling to the development of cardiac electrical instabilities such as repolarization alternans. In this study, we applied a novel combination of techniques (action potential voltage clamping, calcium-transient clamping, and stability analysis) to cardiac cell models to more clearly determine the roles that voltage- and calcium-dependent coupling play in regulating action potential stability and the development of alternans subsequent to the loss of stability. Using these techniques, we are able to demonstrate that voltage- and calcium-dependent coupling exhibit varying degrees of influence on action potential stability across models. Our results indicate that cellular dynamic instabilities such as alternans may be initiated by either voltage- or calcium-dependent mechanisms or by some combination of the two. Based on these modeling results, we propose novel single-cell experiments that incorporate action-potential voltage clamping, calcium imaging, and real-time measurement of action potential stability. These experiments will make it possible to experimentally determine the relative contribution of voltage coupling to the regulation of action potential stability in real cardiac myocytes, thereby providing further insights into the mechanism of alternans.
Measurement of ultrafast hot-carrier relaxation in silicon by thin-film-enhanced, time-resolved reflectivity (1988)

Time-resolved reflectivity measurements with ∼100 fs resolution have revealed an initial 350 fs relaxation time in silicon, believed to be the time it takes hot, photoinjected carriers to relax to the band edge. The measurements were made at low carrier densities (∼1017 cm−3) for which carrier-carrier processes are negligible, and were facilitated by the greater than order of magnitude enhancement of the change in reflectivity signals that can be produced by the use of thin films.
Autonomous Inland Water Monitoring: Design and Application of a Surface Vessel (2012)

This article presents a novel autonomous surface vessel (ASV) that was designed and manufactured specifically for the monitoring of water resources, resources that are not only constantly drained but also face the growing threat of mass proliferation (bloom) of noxious cyanobacteria. On one hand, the distribution of these blooms in a given water body requires a surveillance of biological data at high spatial resolution on both vertical and horizontal axes, whereas on the other hand, the understanding of the temporal evolution of the cyanobacteria necessitates repeated sampling at the same location. Therefore, our ASV was designed to combine the ability to take measurements within a range of depths, with its custom-made winch, and accurate localization provided by the global positioning system (GPS), without the need for static installations. This article first describes the ASV conception, and then the results of extended field tests on the waypoint navigation mode are discussed. Finally, the first results of a sampling campaign for monitoring algal blooms in Lake Zurich are presented. This work constitutes advances in the deployment of mobile measurement platforms for environmental monitoring in lacustrine environments. Furthermore, it investigates the application of a single ASV to capture both spatial and temporal dynamics of harmful cyanobacterial blooms in lakes. Combining surface mobility with depth measurements within a single robot allows fast deployments in remote location, which is cost efficient for lake sampling. This reduces the need for fixed installations, which can be impossible in recreational areas. The high-resolution sampling of lakes will contribute to understand and predict the occurrence of harmful cyanobacterial blooms for a better management of water resources.
Physikalische Chemie 1996 (1997)

Abstract Von besonderer Aktualität in der Kinetik sind Untersuchungen in überkritisch fluider Phase. Die hochauflösende Spektroskopie liefert immer mehr grundlegende Daten für das chemische Verhalten der Moleküle. Membranforschung profitiert von wachsenden Kenntnissen über komplexe (teilgeordnete) Flüssigkeiten. Verschiedene Anwendungen, wie Brennstoffzellen, forcieren die Forschung zum Massen‐ und Ladungstransport in Festkörpern.
Hardware implementation of MIL-STD-1553 protocol over OFDMA-PHY based wireless high data rate avionics systems (2016)

In this paper, a method of improving data rate in avionics systems is proposed which incorporates OFDM transmission technology for high data rate communication. An FPGA-based hardware test bed is developed which uses OFDM physical layer over MIL-STD-1553B communication in RF wireless systems. Finally, a prototype test system is developed using three nodes to emulate Wireless Avionics Intra-Communications (WAIC) over RF systems. The implementation is done on Wireless Open-Access Research Platform (WARP). WARP has virtex-4 FPGA in its core for processing and radio daughter cards that can perform over the air data transmission and reception over 2.4 GHz and 4.5 GHz bands. The real-time performance of the proposed and implemented system is tested using over the air transmission and reception of data traffic. The result shows significant improvement of over the air throughput improvement as compared to the traditional avionics systems with an average Bit Error Rate (BER) satisfying 10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">−3</sup> .
Detection of imperative and declarative question-answer pairs in email conversations (2009)

Question-answer pairs extracted from email threads can help construct summaries of the thread, as well as inform semantic-based assistance with email. Previous work dedicated to email threads extracts only questions in interrogative form. We extend the scope of question and answer detection and pairing to encompass also questions in imperative and declarative forms, and to operate at sentence-level fidelity. Building on prior work, our methods are based on learned models over a set of features that include the content, context, and structure of email threads. For two large email corpora, we show that our methods balance precision and recall in extracting question-answer pairs, while maintaining a modest computation time. 1
Acoustic Echo Cancellation Using Sub-Adaptive Filter (2008)

In the acoustic echo canceller (AEC), the step-size parameter of the adaptive filter must be varied according to the situation if double talk occurs and/or the echo path changes. We propose an AEC that uses a sub-adaptive filter. The proposed AEC can control the step-size parameter according to the situation. Moreover, it offers superior convergence compared to the conventional AEC even when the double talk and the echo path change occur simultaneously. Simulations demonstrate that the proposed AEC can achieve higher ERLE and faster convergence than the conventional AEC. The computational complexity of the proposed AEC can be reduced by reducing the number of taps of the sub-adaptive filter.
On-body characterization of a wearable millimeter-wave antenna for body-centric applications (2011)

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