gebhart/patrepeval huggingface dataset:
Semantic Drift Compensation for Class-Incremental Learning (2020)

Class-incremental learning of deep networks sequentially increases the number of classes to be classified. During training, the network has only access to data of one task at a time, where each task contains several classes. In this setting, networks suffer from catastrophic forgetting which refers to the drastic drop in performance on previous tasks. The vast majority of methods have studied this scenario for classification networks, where for each new task the classification layer of the network must be augmented with additional weights to make room for the newly added classes. Embedding networks have the advantage that new classes can be naturally included into the network without adding new weights. Therefore, we study incremental learning for embedding networks. In addition, we propose a new method to estimate the drift, called semantic drift, of features and compensate for it without the need of any exemplars. We approximate the drift of previous tasks based on the drift that is experienced by current task data. We perform experiments on fine-grained datasets, CIFAR100 and ImageNet-Subset. We demonstrate that embedding networks suffer significantly less from catastrophic forgetting. We outperform existing methods which do not require exemplars and obtain competitive results compared to methods which store exemplars. Furthermore, we show that our proposed SDC when combined with existing methods to prevent forgetting consistently improves results.
Genome‐wide association study in mice identifies loci affecting liver‐related phenotypes including Sel1l influencing serum bile acids (2016)

Genetic analyses of inbred mouse strains identified loci affecting different liver-related traits and implicated Sel1l as a significant determinant of serum bile acid concentration. (Hepatology 2016;63:1943-1956).
Thermal tuning of volume Bragg gratings for high power spectral beam combining (2010)

A tabletop kW-level spectral beam combining (SBC) system using volume Bragg gratings (VBGs) recorded in photothermo- refractive (PTR) glass was presented at the last meeting [<sup>1]</sup>. Diffraction efficiency of VBGs close to 100% was demonstrated. However, when using VBGs for spectral beam combining, it is important to ensure high diffraction efficiency for the diffracted beam and low diffraction efficiency for the transmitted beams simultaneously. The unique, unmatched properties of VBGs allow spectral beam combining achieving this condition at wavelengths with less than 0.25 nm separation. We present modeling of reflecting VBGs for high power SBC that takes into account laser spectral bandwidth, beam divergence, PTR-glass scattering losses, and grating non-uniformity. A method for optimization of VBG parameters for high-efficiency SBC with an arbitrary number of channels is developed. Another important aspect of spectral beam combiner design is maintaining high diffraction efficiency as the temperature of beam-combining VBGs changes during operation due to absorption of high power radiation. A new technique of thermal tuning of large aperture VBGs, designed to maintain high efficiency of beam combining without mechanical adjustment over a wide range of laser power, is developed. Finally, these tools are used to demonstrate a robust and portable 5-channel SBC system with near diffraction limited spectrally-combined output beam.
Underfoot pressure distribution in patients after surgical treatment of proximal end of femoral bone (2009)

Aim: The aim of this study was to estimate the underfoot pressure distribution in patients after fractures of the proximal end of femoral bone. Material and methods: We examined 22 patients, both sexes, aged 58-76 after an operative treatment of a fracture of the neck of femoral bone (9 patients,) or a pertrochanteric fracture (13 patients) and finishing of the rehabilitation. The examinations were performed av. 2,8 y after surgical treatment. The control group consisted of 40 healthy subjects. We used physical examination, Xray, and underfoot pressure measurements using static and postural pedobarographic tests. The plantar pressure was determined at foot regions distinguished on the ground of classification of Blomgren’s. Results: In all patients we found the reduction of the hip joint movement range (mainly hyperextension, internal rotation), in radiological study the total healing of the fracture, and in 7 cases moderately advanced degenerative changes of the hip joint. Pedobarographic examination revealed that on the operated side in 12 patients was a decreased pressure under T and H foot regions on the operated side, in 6 - a decreased pressure under MT1-MT5 foot regions, in 3 - a decreased pressure under all foot regions and in 1 patient an increased pressure under T and H foot regions. Conclusion: Pedobarography revealed lack of complete return of normal weight-bearing of the plantar surface of the foot av. 2,8 years after surgery because of the femur bone proximal end fracture.
Aminosilane-Functionalized Cellulosic Polymer for Increased Carbon Dioxide Sorption (2011)

Improvement in the efficiency of CO2 separation from flue gases is a high-priority research area to reduce the total energy cost of carbon capture and sequestration technologies in coal-fired power plants. Efficient CO2 removal from flue gases by adsorption systems requires the design of novel sorbents capable of capturing, concentrating, and recovering CO2 on a cost-effective basis. This paper describes the preparation of an aminosilane-functionalized cellulosic polymer sorbent with enhanced CO2 sorption capacity and promising performance for use in postcombustion carbon capture via rapid temperature-swing adsorption systems. The introduction of aminosilane functionalities onto the backbone of cellulose acetate was achieved by the anhydrous grafting of N-(2-aminoethyl)-3-aminoisobutyldimethylmethoxysilane. The dry sorption capacity of the modified cellulosic polymer reached 27 cc (STP) CO2/cc sorbent (1.01 mmol/g sorbent) at 1 atm and 39 cc (STP) CO2/cc sorbent (1.46 mmol/g sorbent) at 5 atm and 308 K. The amine loading achieved was 5.18 mmol amine(nitrogen)/g sorbent. Exposure to water vapor after the first dry sorption cycle increased the dry sorption capacity of the sorbent by 12% at 1 atm, suggesting its potential for rapid cyclic adsorption processes under humid feed conditions. The CO2 sorbent was characterized in terms of chemical composition, density changes, molecular structure, thermal stability, and surface morphology.
Supplementary Table 4 from &lt;i&gt;CHFR&lt;/i&gt; Promoter Methylation Indicates Poor Prognosis in Stage II Microsatellite Stable Colorectal Cancer (2023)

&lt;p&gt;Correlations between promoter CpG island methylation of 19 tumor suppressor/DNA repair genes, MSI, BRAF, KRAS and CIMP in the study population.&lt;/p&gt;
Global optimization: techniques and applications (2000)

Optimization problems arise in a wide variety of scientific disciplines. In many practical problems, a global optimum is desired, yet the objective function has multiple local optima. A number of techniques aimed at solving the global optimization problem have emerged in the last 30 years of research. This thesis first reviews techniques for local optimization and then discusses many of the stochastic and deterministic methods for global optimization that are in use today. Finally, this thesis shows how to apply global optimization techniques to two practical problems: the image segmentation problem (from imaging science) and the 3-D registration problem (from computer vision).
Description of a New Species of Cephalocarida, Sandersiella Kikuchii, and Redescription of S. Acuminata Shiino Based upon the Type Material (2008)

A new species of cephalocarid, Sandersiella kikuchii, is described from central Japan, 300 m depth. It differs from congeners primarily based on the following points: 5-9 hooks on each ventrolateral side of cephalon; exopod proximal segment of thoracopod 6 with long finger-like lateral process (with narrow base) on the dorsal margin; exopodal distal segment of thoracopod 6 pointed distally, not divided into 2 lobes; exopodal proximal segment and pseudopipod of thoracopod 8 furnished with 2 and 2-3 setae respectively. Sandersiella acuminataShiino, 1965 is redescribed and illustrated based on the holotype.
Supplementary Figure S2 from A Dendritic Cell Vaccine Pulsed with Autologous Hypochlorous Acid-Oxidized Ovarian Cancer Lysate Primes Effective Broad Antitumor Immunity: From Bench to Bedside (2023)

&lt;p&gt;Supplementary Figure S2 - PDF file 84K, Phenotype of DCs following lysate-pulsing (i.e. HOCl-L, UVB-L or FTL), and activation with LPS and IFN-gamma. Unpulsed, mature (mDC) or immature DCs (iDC) served as controls. Data was presented as mean plus-minus SEM&lt;/p&gt;
IFN-gamma-mediated coordinated transcriptional regulation of the human TAP-1 and LMP-2 genes in human renal cell carcinoma. (1997)

Some human tumor cells exhibit deficient expression of the peptide transporters TAP1 and TAP2 and of the proteasome subunits low molecular weight protein (LMP)-2 and LMP-7, which could be partially restored by cytokine treatment. Here, we show that IFN-gamma stimulation of human renal cell carcinoma lines increased the MHC class I, transporter associated with antigen processing (TAP), and LMP transcript and protein levels, but TAP and LMP expression are more rapidly induced by IFN-gamma than MHC class I molecules. No correlation between the level of induction of the MHC class I antigen presentation genes and IFN sensitivity/resistance was detected. The IFN-gamma-mediated increase of MHC class I, TAP-1, and LMP-2 expression was independent of de novo protein synthesis. Analysis of the dual TAP-1/LMP-2 promoter activity revealed that TAP-1 and LMP-2 expression are controlled by IFN-gamma at the transcriptional level. Site-specific mutations in the IFN-gamma-responsive element of the TAP-1/LMP-2 promoter blocked induction by IFN-gamma. Thus, the IFN-gamma-mediated coordinated transcriptional up-regulation of TAP-1 and LMP-2 expression occurs through the use of a common regulatory element, which might result in enhanced recognition of renal cell carcinoma cells by the immune system.
(tert‐Butyldimethylsilyl)Allene (2003)

Abstract (tert‐butyldimethylsilyl)allene intermediate: 2‐propargyloxytetrahydropyran intermediate: 3‐(tert‐butyldimethylsilyl)‐2‐propyn‐1‐ol catalyst: 13.0 g (60.0 mmol) of o‐nitrobenzenesulfonyl hydrazide product: (tert‐butyldimethylsilyl)allene
MOS current mode logic for low power, low noise CORDIC computation in mixed-signal environments (2000)

In this work, MOS Current Mode Logic (MCML) is analyzed for application to low power, mixed signal environments.A small MCML cell library is developed and optimized for several different performance requirements.The cells are then applied to the generation of piplelined CORDIC structures and compared with equivalent CMOS circuits.MCML CORDICs are designed which can operate from 125MHz to 310MHz with power consumption varying between 4.3mW and 18.6mW.These power results are up to 1.5 times less than CMOS CORDICs with equivalent propagation delays.Design was done in a 0.25µm standard CMOS process from ST Microelectronics.
Growth and optical properties of In x Ga1−x P nanowires synthesized by selective-area epitaxy (2016)

Ternary III–V nanowires (NWs) cover a wide range of wavelengths in the solar spectrum and would greatly benefit from being synthesized as position-controlled arrays for improved vertical yield, reproducibility, and tunable optical absorption. Here, we report on successful selective-area epitaxy of metal-particle-free vertical In x Ga1−x P NW arrays using metal–organic vapor phase epitaxy and detail their optical properties. A systematic growth study establishes the range of suitable growth parameters to obtain uniform NW growth over a large array. The optical properties of the NWs were characterized by room-temperature cathodoluminescence spectroscopy. Tunability of the emission wavelength from 870 nm to approximately 800 nm was achieved. Transmission electron microscopy and energy dispersive X-ray measurements performed on cross-section samples revealed a pure wurtzite crystal structure with very few stacking faults and a slight composition gradient along the NW growth axis.
18/#499 Mirvetuximab soravtansine and carboplatin for treatment of patients with recurrent folate receptor alpha-positive platinum-sensitive ovarian cancer: a final analysis (2022)

<h3>Objectives</h3> Mirvetuximab soravtansine (MIRV) is a first-in-class ADC comprising a folate receptor-α (FRα)-binding antibody, cleavable linker, and maytansinoid DM4 payload. As part of the phase 1b/2 trial (NCT02606305), efficacy and safety of MIRV and carboplatin (carbo) were evaluated in patients with recurrent FRα-positive platinum sensitive ovarian cancer (PSOC) measured by immunohistochemistry (PS2+ ≥25%; table 1). <h3>Methods</h3> Eighteen patients received MIRV and carbo intravenously on Day 1 of a 3-week cycle using a standard 3 + 3 design, with a starting dose of MIRV 5 mg/kg adjusted ideal body weight (AIBW) and carbo AUC4. FRα positivity by immunohistochemistry (PS2+ ≥25%) was required. Primary endpoint was confirmed ORR by RECIST v1.1. <h3>Results</h3> Ten patients received MIRV 6 mg/kg AIBW and carbo AUC5. Anti-tumor activity was observed in all dose escalation cohorts with varying levels of FRα expression. Patients receiving MIRV 6 mg/kg AIBW and carbo AUC5 had an ORR of 89%, mDOR of 12.1, and mPFS of 16.5 months. Patients with medium/high FRα-expressing tumors had an ORR of 80%, mDOR of 24.2, and mPFS of 15.0 months across all escalation cohorts (table 2). The most frequent treatment-emergent adverse events (all, grade 3+) included nausea (72%, 0%), diarrhea (67%, 6%), blurred vision (67%, 0%), thrombocytopenia (61%, 17%), fatigue (61%, 11%), and neutropenia (56%, 28%). <h3>Conclusions</h3> MIRV and carbo demonstrated anti-tumor activity in patients with recurrent FRα-positive PSOC. MIRV 6 mg/kg AIBW and carbo AUC5 was selected as the phase 2 dose. This combination is being evaluated in one planned and two ongoing (NCT04606914 and NCT04274426) studies.
Random feature maps via a Layered Random Projection (LARP) framework for object classification (2016)

The approximation of nonlinear kernels via linear feature maps has recently gained interest due to their applications in reducing the training and testing time of kernel-based learning algorithms. Current random projection methods avoid the curse of dimensionality by embedding the nonlinear feature space into a low dimensional Euclidean space to create nonlinear kernels. We introduce a Layered Random Projection (LaRP) framework, where we model the linear kernels and nonlinearity separately for increased training efficiency. The proposed LaRP framework was assessed using the MNIST hand-written digits database and the COIL-100 object database, and showed notable improvement in object classification performance relative to other state-of-the-art random projection methods.
Probing the Signature of Disordering and Delocalization of Oxygen Vacancies and Anti-site Defects in Doped LaAlO<sub>3</sub> Solid Electrolytes (2022)

Correlation of structural, vibrational, and optical properties with the oxygen ion conductivity mechanism in Ca and Mg single and co-doped LaAlO3 solid electrolytes synthesized via the sol–gel technique has been explored in the intermediate temperature range of 350–700 °C. The disordering of oxygen vacancies has been analyzed through temperature-dependent Raman spectroscopy in doped LaAlO3. Faster disordering of oxygen defects associated with AlO6 octahedra and LaO12 dodecahedra has been observed in lesser distorted samples (higher Ca content) with temperature, but at the same time, the defect concentration of oxygen vacancies crucially impacts the ionic conductivity mechanism. Experimental evidence of oxygen and anti-site defects has been probed through optical absorption spectroscopy in the diffused reflectance mode, wherein the temperature-dependent diffuse reflectance spectra indicate the delocalization of oxygen vacancies and anti-site defects above 250 and 300 °C, respectively. Comprehensively, temperature-dependent Raman and optical absorption spectroscopies have emerged as influential techniques for probing the signature of disordering and delocalization of oxygen vacancies and anti-site defects in solid-state oxide-based materials.
Clonage du gene de la L-lactate deshydrogenase de Lactobacillus sake (1994)

*INRA, Laboratoire de Recherches sur la Viande, Jouy en Josas Diffusion du document : INRA, Laboratoire de Recherches sur la Viande, Jouy en Josas
Fabrication of a Polymeric Optical Waveguide-On-Flex Using Electrostatic-Induced Lithography (2010)

A method has been developed for the manufacture of polymeric multimode waveguides using an electrostatic field-induced self assembly and pattern formation process. A spin-coated liquid optical polymer placed between two conductive plates experiences an electrostatic force from an applied electric field gradient across the plates. Surface electrohydrodynamics instability patterning is employed to fabricate optical core microstructures using a patterned master plate. The result shows a good replication of the pattern from the master plate to the optical polymer. The process protocols were defined to achieve waveguides with low sidewall roughness together with an optical coupling interface. We have demonstrated multimode waveguide arrays with a 50 μm × 50 μm cross section and 250-μm pitch on a 10 mm × 10 mm flexible substrate. The refractive index and absorption measurement of the electrostatic-induced optical film show insignificant changes when compared with the unexposed film. Using the cutback approach, the propagation loss of the waveguide is measured at -1.97 dB/cm. The whole fabrication process is found to be fast, cost-effective, and no photosensitive material is needed as in the conventional photolithography approach.
Vein minutia cylinder-codes (V-MCC) (2013)

Vein recognition has been extensively studied in the past. The topology of the vein patterns allows to adopt simple representations, based on edges and their endings, which are quite similar to the fingerprint minutiae. In this paper, the Minutia Cylinder-Codes (MCC), developed for the comparison of fingerprint minutiae, are adapted to characterize vein minutiae. The algorithm adaptation requires to understand the vein topology and how to consequently define the parameter sets. An optimization problem is defined and solved using a genetic algorithm (GA) approach. The experimental results prove the applicability of MCC on three extended vein data sets of wrist and palm dorsal. The performance of the reference parameter set is improved and can compete with other state-of-the-art algorithms for vein verification.
Potential of Anisopteromalus calandrae (Hymenoptera: Pteromalidae) as biocontrol agent of Callosobruchus maculatus (F.) (Coleopetera: Bruchidae) (2007)

The bruchid Callosobruchus maculatus (F.) (Coleopetera: Bruchidae) is a major pest of stored cowpea Vigna unguiculata (Walp.) in Africa and particularly in northern Cameroon. Anisopteromalus calandrae (Hymenoptera: Pteromalidae) parasitoid of its larval stages, could be used in the biological control of this grain pest. In field conditions, 5 months samples in small holder granaries established the phenological relationship between this parasitoid and its host. Large amount of A. calandrae may efficiently control C. maculatus infestations. Laboratory assays made an evidence of the preference of A. calandrae to parasitise 4th instar larvae of C. maculatus. To estimate the suitable density of the infesting population of parasitoid, other experiments pointed out that one mated female induced reduction of 4.97% of emergence of C. maculatus while 4 females performed more. The reduction of emergence observed was 42.34%. In suitable density, A. calandrae may play an important role in the biological control of C. maculatus on cowpea during storage.
Supplementary Figure 1 from Compensatory Pathways Induced by MEK Inhibition Are Effective Drug Targets for Combination Therapy against Castration-Resistant Prostate Cancer (2023)

Supplementary Figure 1 from Compensatory Pathways Induced by MEK Inhibition Are Effective Drug Targets for Combination Therapy against Castration-Resistant Prostate Cancer
Glancing angle XAFS and X-ray reflectivity studies of transition-metal/aluminium interfaces (1990)

The combination of glancing angle X-ray absorption fine structure (XAFS) and X-ray reflectivity measurements provide detailed structural information about interfaces. Results from transition-metal/Al interfaces are used to illustrate the capabilities of the techniques. Reflectivity measurements are used to determine the thickness and density profile of the films, along with the amount of interfacial or surface roughness. The XAFS measurements provide information about the local bonding at the interface, and are well suited for studying the interfacial chemistry. Of interest is the role of impurities such as oxygen in modifying interface structure and thermal stability. For Cu/Al, Ni/Al and Cr/Al a small amount of interfacial oxygen is found to affect strongly both the initial interface structure, and the response of the interface to thermal annealing. For Ni/Al it is also found that interfacial oxygen affects primarily the interface reaction, while oxygen within the Al layer suppresses the grain boundary reaction channel.
Opportunistic PLP: Maximizing the Spectrum Usage in DTT (2022)

Broadcasting services are continuously evolving, especially after the advent of full-IP standards like ATSC 3.0. Despite this rapid change, there are still daunting challenges to address. For instance, the broadcasting network can not be dynamically auto-configured, and requires continuous operation actions from Broadcast Network Operators (BNOs). However, the Broadcast Core Network, a new entity under development, will provide intelligence to this system equivalent to what is done in Cellular Networks, and what is more, it also opens a window to reach an auto-managed system. In a previous work, the authors proposed upgrading traditional transmission facilities with a Spectrum Optimization Software Module, which can dynamically add/remove/modify the services within PLPs. However, in the legacy solution, there is always some unused capacity as the media and PLP capacity are not 100% aligned. Therefore, this paper proposes a mechanism to maximize spectrum efficiency by inserting a new datacasting service in the available free space: an opportunistic PLP. The paper describes the practical demonstration that shows the potential of this new approach.
Film forming polymeric ionic liquids (PILs) based on polybenzimidazoles for CO<sub>2</sub>separation (2013)

PILs are emerging as promising materials for CO2 capture. Film formation, which is a requisite for membrane formation, is induced in a family of PILs by N-substituting a rigid thermo-mechanically stable polybenzimidazole, followed by metathesis. This provided two IL groups per repeat unit of the PIL and enhanced the CO2 separation characteristics.
Oxygen Reduction on Teflon Bonded Pt/WO[sub 3]/C Electrode in Sulfuric Acid (2001)

Highly dispersed was prepared by freeze-drying followed by hydrogen reduction. The catalyst particle size was examined by transmission electron microscopy and X-ray diffraction line broadening technique as well as electrochemical Pt surface area measurement by and CO stripping. Oxygen reduction on Teflon bonded electrode was investigated under and air in 0.5 M at 25 and 70°C. was more active for oxygen reduction in sulfuric acid than Pt/C catalyst. The dissolved tungsten compounds (peroxy-tungstate) from the in the electrode participate in the oxygen reduction as a homogeneous catalyst for the decomposition of leading to significantly higher activity of the for oxygen reduction. By coating the electrode with a thin layer Nafion dispersion, continual loss of by dissolution and diffusion to the bulk electrolyte is avoided. © 2001 The Electrochemical Society. All rights reserved.