gebhart/patrepeval huggingface dataset:
Master-Slave principle applied to an electrically-tunable swept source-OCT system (2020)

In this communication, we evaluate the suitability of Master-Slave (MS) optical coherence tomography (OCT) for processing of interferograms generated by an interferometer driven by an akinetic, electrically-tunable swept source from Insight with an ultra-large instantaneous coherence length. The akinetic source is programmed to sweep linearly, but within the sweep, at predictable times, the laser tuning introduces invalid regions in the interferogram, which are normally removed post-acquisition using a pre-calibration file. This makes sure that any optical frequency component is used once only and enables correct operation of a Fourier transform (FT). A FT applied to an unprocessed emitted spectrum leads to wide and numerous peaks in the A-scan. MS processing was introduced to avoid the necessary corrections demanded by conventional FT signal processing or its derivatives. The MS procedure consists of comparing photo-detected signals at the output of two interferometers, a Slave and a Master interferometer. The MS method was advanced along two avenues, either by using (i) electricallygenerated master signals (making use of the same interferometer twice) or (ii) optically-generated master signal via a recently introduced MS down-conversion procedure. We apply both avenues to the Insight source. Approach (i) tests the MS principle as an alternative to the Insight file correction while (ii) demonstrates near coherencelimited operation at a large axial range (&gt;80 mm) for which a too-high sampling rate digitizer would have been needed. In this communication, we evaluate for the first time the suitability of the MS procedure to OCT measurements performed with the akinetic swept source commercialized by Insight. Two modalities are evaluated to implement the MS processing, based on: (i) digital generation of the master signals using the OCT interferometer and (ii) down conversion using a second interferometer driven by the swept source.
HPI Future SOC Lab – Proceedings 2017 (2019)

The “HPI Future SOC Lab” is a cooperation of the Hasso Plattner Institute (HPI) and industry partners. Its mission is to enable and promote exchange and interaction between the research community and the industry partners. The HPI Future SOC Lab provides researchers with free of charge access to a complete infrastructure of state of the art hard and software. This infrastructure includes components, which might be too expensive for an ordinary research environment, such as servers with up to 64 cores and 2 TB main memory. The offerings address researchers particularly from but not limited to the areas of computer science and business information systems. Main areas of research include cloud computing, parallelization, and In-Memory technologies. This technical report presents results of research projects executed in 2017. Selected projects have presented their results on April 25th and November 15th 2017 at the Future SOC Lab Day events.
The HEV Ventilator: at the interface between particle physics and biomedical engineering (2022)

A high-quality, low-cost ventilator, dubbed HEV, has been developed by the particle physics community working together with biomedical engineers and physicians around the world. The HEV design is suitable for use both in and out of hospital intensive care units, provides a variety of modes and is capable of supporting spontaneous breathing and supplying oxygen-enriched air. An external air supply can be combined with the unit for use in situations where compressed air is not readily available. HEV supports remote training and post market surveillance via a Web interface and data logging to complement standard touch screen operation, making it suitable for a wide range of geographical deployment. The HEV design places emphasis on the ventilation performance, especially the quality and accuracy of the pressure curves, reactivity of the trigger, measurement of delivered volume and control of oxygen mixing, delivering a global performance which will be applicable to ventilator needs beyond the COVID-19 pandemic. This article describes the conceptual design and presents the prototype units together with a performance evaluation.
Angiomyofibroblastoma‐like tumors (cellular angiofibroma) (2006)

Angiomyofibroblastoma-like tumor (cellular angiofibroma) is a rare, circumscribed, slow-growing mesenchymal tumor that occurs predominantly in the vulva, perineum, and pelvis of women. We report two cases of this tumor in men arising as paratesticular masses of the scrotum, summarize the history of this tumor, and discuss why efforts should be made to differentiate it from aggressive angiomyxoma. Recommended treatment is complete surgical excision with long-term follow up exams, as local recurrence may occur many years after resection of the lesion.
Roughness Based Crossflow Transition Control for a Swept Airfoil Design Relevant to Subsonic Transports (2010)

A high fidelity transition prediction methodology has been applied to a swept airfoil design at a Mach number of 0.75 and chord Reynolds number of approximately 17 million, with the dual goal of an assessment of the design for the implementation and testing of roughness based crossflow transition control and continued maturation of such methodology in the context of realistic aerodynamic configurations. Roughness based transition control involves controlled seeding of suitable, subdominant crossflow modes in order to weaken the growth of naturally occurring, linearly more unstable instability modes via a nonlinear modification of the mean boundary layer profiles. Therefore, a synthesis of receptivity, linear and nonlinear growth of crossflow disturbances, and high-frequency secondary instabilities becomes desirable to model this form of control. Because experimental data is currently unavailable for passive crossflow transition control for such high Reynolds number configurations, a holistic computational approach is used to assess the feasibility of roughness based control methodology. Potential challenges inherent to this control application as well as associated difficulties in modeling this form of control in a computational setting are highlighted. At high Reynolds numbers, a broad spectrum of stationary crossflow disturbances amplify and, while it may be possible to control a specific target mode using Discrete Roughness Elements (DREs), nonlinear interaction between the control and target modes may yield strong amplification of the difference mode that could have an adverse impact on the transition delay using spanwise periodic roughness elements.
Measurement-Based Modal Beamforming Using Planar Circular Microphone Arrays (2014)

This paper describes how to use a planar circular pressure-zone table-top microphone array for modal beamforming. Its goals are similar as for spherical arrays: higher-order resolution and a more-or-less steering-invariant beampattern design in the three-dimensional half space. As conventional circular arrays lack control of the beampattern in the vertical array plane, the proposed arrangement tries to fix this shortcoming to allow both horizontal and vertical control of beamforming. To provide a fully calibrated decomposition into the directional modes, the proposed beamforming approach is based on measurement data. From a MIMO (multiple-input-multiple-output) system description of the measurement data in the spherical harmonics domain, an inverse MIMO system of filters is designed for decomposing the microphone array signals into those spherical components eligible for modal beamforming. For an efficient measurement and robust set of decomposition filters, a reduced set of measurement positions and a regularisation strategy is suggested.
170 GHz SiGe-BiCMOS Loss-Compensated Distributed Amplifier (2014)

This paper presents a travelling-wave amplifier (TWA) for wideband applications implemented in a 0.13 μm SiGe BiCMOS technology (ft = 300 GHz, fmax = 500 GHz). The gain cell employed in the TWA is designed to compensate the transmission-line- losses at high frequencies in order to extend the bandwidth as well as the gain bandwidth product (GBP). A gain of 10 dB and a 3-dB bandwidth of 170 GHz are measured for the fabricated TWA. The chip has a chip area of 0.38 mm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> and a power consumption of 108 mW. Compared against the state of the art, the presented design achieves the highest reported GBP per area and power consumption.
Leucocyte and platelet‐derived bioactive substances in stored blood: effect of prestorage leucocyte filtration (1997)

Adverse reactions to transfusion of allogeneic blood may depend on content of leucocytes and platelets and on storage-time of the erythrocyte suspensions. Therefore, we studied the efficacy of prestorage leucocyte reduction by filtration on total content and extracellular accumulation of histamine, eosinophil cationic protein (ECP), eosinophil protein X (EPX), myeloperoxidase (MPO), plasminogen activator inhibitor type-1 (PAI-1) and interleukin-6 (IL-6) in samples obtained from 5 units of SAGM blood, 7 units of plasma-reduced whole-blood and 6 units of whole-blood before and after filtration, respectively. In addition, we analysed supernatants from the same units after storage at +4 degrees C for 0, 21 and 35 d, respectively. The filtration was performed at room temperature within 2-4 h after donation. The substances were analysed by ELISA and RIA methods and we also analysed the donor plasma levels of the same bioactive substances. The total content of histamine, ECP, EPX, and MPO were 10-70-fold higher in all unfiltered erythrocyte products compared to donor plasma concentrations, while PAI-1 content was 15-20-fold higher only in plasma-reduced whole-blood and whole-blood. Prestorage leucocyte filtration significantly reduced the total histamine, ECP, EPX, MPO and PAI-1 content to levels similar to donor plasma levels in plasma-reduced whole-blood and whole-blood, while PAI-1 was still low in filtered SAGM blood. In addition, the levels of extracellular bioactive substances at d 0 after donation and filtration were within the range of concentrations in donor plasma, and there was no time-dependent accumulation during storage for 35 d at +4 degrees C. IL-6 was not detected in either plasma or samples obtained from the blood bags. These results suggest prestorage leucocyte filtration to deplete leucocyte contents to levels, which prevent the previously shown time-dependent accumulation of leucocyte derived bioactive substances in various erythrocyte suspensions. In addition, the PAI-1 results suggest leucocyte filters to reduce the obligatory platelet content in whole-blood products.
Fundamental Limits of Infinite Constellations in MIMO Fading Channels (2011)

The fundamental and natural connection between the infinite constellation (IC) dimension and the best diversity order it can achieve is investigated in this paper. In the first part of this work we develop an upper bound on the diversity order of IC for any dimension and any number of transmit and receive antennas. In the second part of this work we prove that by choosing the correct dimensions, IC in general and lattices in particular can achieve the optimal diversity-multiplexing tradeoff of finite constellations. This work gives a framework for designing lattices for multiple-antenna channels using lattice decoding.
Spatial colocalization and functional link of purinosomes with mitochondria (2016)

Purine biosynthetic enzymes organize into dynamic cellular bodies called purinosomes. Little is known about the spatiotemporal control of these structures. Using super-resolution microscopy, we demonstrated that purinosomes colocalized with mitochondria, and these results were supported by isolation of purinosome enzymes with mitochondria. Moreover, the number of purinosome-containing cells responded to dysregulation of mitochondrial function and metabolism. To explore the role of intracellular signaling, we performed a kinome screen using a label-free assay and found that mechanistic target of rapamycin (mTOR) influenced purinosome assembly. mTOR inhibition reduced purinosome-mitochondria colocalization and suppressed purinosome formation stimulated by mitochondria dysregulation. Collectively, our data suggest an mTOR-mediated link between purinosomes and mitochondria, and a general means by which mTOR regulates nucleotide metabolism by spatiotemporal control over protein association.
Design update and recent results of the Apollon 10 PW facility (2017)

In this paper we are giving a summary of the Apollon 10 PW facility laser design together with updated laser performance. The Apollon facility is currently under construction in France. The APOLLON laser system is a laser designed for delivering pulses as short as 15 fs (10<sup>-15</sup> s) with an energy exceeding 150 Joules on target. The peak power delivered by this laser system will be 10 Petawatts (10<sup>16</sup>W). The Apollon laser system will be delivering 4 beams: one 10 PW beam (F1 beam 400 mm diameter), one 1 PW beam (F2 beam 140 mm diameter) and two additional probe beams (F3 and F4) at a repetition rate of 1 shot per minute. The laser system is based on Ti-sapphire amplifiers pumped by frequency doubled solid-state lasers. The repetition rate of the high energy part will be 1 shot per minute. The main beam at the output of the last amplifier will be split and dispatched to two experimental areas. The main laser beam is delivering 30 J before compression at a repetition rate of 1 shot per minute and we are currently increasing to get 100J.
General Ability Index for the WAIS-III: Canadian Norms. (2005)

La troisieme edition de l'echelle Wechsler de l'intelligence adulte (WAIS-III; Wechsler, 1997) permet le calcul a la fois du QI classique et de scores indiciels. Les indices de comprehension verbale et d'organisation perceptuelle possedent les coefficients « g » les plus eleves en comparaison des indices de memoire de travail et de vitesse de traitement, susceptibles d'etre plus sensibles a certains troubles neuro-cognitifs. Dans certaines situations cliniques, il est souhaitable de recueillir des scores composites d'aptitude generale fondes sur un ensemble limite a l'indice verbal et a l'indice de performance. Conformement a la methode de calcul de l'indice d'aptitude generale (GAI; Prifitera, Weiss et Saklofske, 1998) aux fins de la troisieme edition de l'echelle Wechsler de l'intelligence des enfants (WISC-III; Wechsler, 1991) et du WAIS-III (Tulsky, Saklofske, Wilkins et Weiss, 2001), les auteurs presentent des tables normatives de l'indice d'aptitude generale faisant etat de l'echantillon de normalisation canadienne du WISC-III pour completer les tables normatives canadiennes de l'indice d'aptitude generale relative au WISC-III parues anterieurement.
Acetyl Substitution of the O-Specific Caryan from the Lipopolysaccharide of Pseudomonas (Burkholderia) caryophylli Leads to a Block Pattern (2000)

An exceptionally large repeating unit has been proposed for one of the two O-specific polysaccharides of the lipopolysaccharide from Pseudomonas (Burkholderia) caryophylli, which is a homopolymer of the sugar caryose. This proposal is based on the unusual acetylation pattern of the carbohydrate (shown in the picture), as determined from the presence of eight independent spin systems observed by NMR spectroscopy. A=acetylated, D=non-acetylated caryose monomer.
Modular Conformer Training for Flexible End-to-End ASR (2023)

The state-of-the-art conformer used in automatic speech recognition combines feed-forward, convolution and multi-headed self-attention layers in a single model that is trained end-to-end with a decoder network. While this end-to-end training is simple and beneficial for word error rate, it restricts the ability to perform inference with the model at different operating points of word error rate and latency. Existing approaches to overcome this limitation include cascaded encoders and variable attention context models. We propose an alternative approach, called Modular Conformer training, which splits the Conformer model into a backbone convolutional model and attention submodels, which are added at each layer. We conduct experiments with a few training techniques on the Librispeech and Librilight corpus. We show that dropping-out the attention layers during the training of the backbone model allows for the largest WER improvements upon adding fine-tuned attention submodels, without impacting the WER of the backbone model itself.
Information is not a Virus, and Other Consequences of Human Cognitive Limits (2016)

The many decisions people make about what to pay attention to online shape the spread of information in online social networks. Due to the constraints of available time and cognitive resources, the ease of discovery strongly impacts how people allocate their attention to social media content. As a consequence, the position of information in an individual's social feed, as well as explicit social signals about its popularity, determine whether it will be seen, and the likelihood that it will be shared with followers. Accounting for these cognitive limits simplifies mechanics of information diffusion in online social networks and explains puzzling empirical observations: (i) information generally fails to spread in social media and (ii) highly connected people are less likely to re-share information. Studies of information diffusion on different social media platforms reviewed here suggest that the interplay between human cognitive limits and network structure differentiates the spread of information from other social contagions, such as the spread of a virus through a population.
Laser Pneumatic Retinopexy for Repair of Recurrent Retinal Detachment After Failed Scleral Buckle-Ten Years Experience (2001)

We believe that laser pneumatic retinopexy repair of recurrent retinal detachments following scleral buckle and without significant proliferation vitreoretinopathy (PVR) should be considered ahead of conventional surgical intraoperative techniques. Laser pneumatic retinopexy may be a very successful procedure for the treatment of recurrent retinal detachments after failed scleral buckle surgery. In a consecutive series of 40 eyes with recurrent retinal detachment, we were able to repair 36 with pneumatic retinopexy alone.
Ultra‐schnelle Präparation großflächiger Graphdiin‐basierter Membranen mittels Alkin‐Oberflächenmodifizierung (2023)

Abstract Graphdiine (engl. graphdiynes=GDYs) sind zweidimensionale graphenähnliche Kohlenstoffsysteme und gelten aufgrund ihrer einzigartigen physikalisch‐chemischen Eigenschaften als potenzielles Membranmaterial. Die Maßstabvergrößerung der Präparation von GDY‐Membranen ist jedoch eine technologische Herausforderung. Wir berichten hier über eine einfache und effiziente alkinierte oberflächenvermittelte Strategie zur Herstellung von wasserstoffsubstituierten Graphdiin [1c] (HsGDY)‐Membranen auf kommerziellen Aluminiumoxidrohren, die zuvor Alkin‐modifiziert wurden. Die Oberflächenalkinierung der Keramik erlaubt eine oberflächenbegrenzte Kupplungsreaktion in Gegenwart eines Kupferkatalysators und ermöglicht so das epitaktische Wachstum von HsGDY im Nanomaßstab. Eine kontinuierliche und ultradünne HsGDY‐Membran (∼100 nm) kann innerhalb von 15 min hergestellt werden. Die resultierenden Membranen weisen eine sehr hohe Molekularsiebung zusammen mit hervorragender Wasserpermeanz (ca. 1100 L m −2 h −1 MPa −1 ) auf und zeigen aufgrund der superhydrophilen Oberfläche und hydrophoben Porenwände ein stabiles Trennverhalten in der Cross‐Flow‐Nanofiltration.
A Support Vector Machine based Prediction Model for Discrimination of Malignant Pulmonary Nodules from Benign Nodules (2016)

Lung cancer is the leading cause of cancer death in the United States and worldwide. Most patients are

diagnosed at an advanced stage, usually stage III or IV. Identification of lung cancer patients at an early

stage might enable oncologists to surgically remove the tumors. Currently, low dose CT scans are used to

identify the malignant nodules in high risk patients. However, screening CT scans yield a high rate of false-positive

results. A prediction model was developed for improved discrimination of malignant nodules from

benign nodules in patients who underwent lung screening CT. CT images and clinical outcomes of 39

patients were obtained from the National Lung Screening Trial (NLST), National Cancer Institute, National

Institute of Health. Images were analyzed to extract computational features relevant to malignancy

prediction. A Support Vector Machine (SVM) based model was developed to predict the malignancy of

nodules. During pilot studies, our model achieved the following prediction performance: accuracy of 0.74,

sensitivity of 0.85, and specificity of 0.61.
Chitosan Hydrogels for the Regeneration of Infarcted Myocardium: Preparation, Physicochemical Characterization, and Biological Evaluation (2016)

The formation of chitosan hydrogels without any external cross-linking agent was successfully achieved by inducing the gelation of a viscous chitosan solution with aqueous NaOH or gaseous NH3. The hydrogels produced from high molecular weight (Mw ≈ 640 000 g mol(-1)) and extensively deacetylated chitosan (DA ≈ 2.8%) at polymer concentrations above ∼2.0% exhibited improved mechanical properties due to the increase of the chain entanglements and intermolecular junctions. The results also show that the physicochemical and mechanical properties of chitosan hydrogels can be controlled by varying their polymer concentration and by controlling the gelation conditions, that is, by using different gelation routes. The biological evaluation of such hydrogels for regeneration of infarcted myocardium revealed that chitosan hydrogels prepared from 1.5% polymer solutions were perfectly incorporated onto the epicardial surface of the heart and presented partial degradation accompanied by mononuclear cell infiltration.
Molecular Propellers that Consist of Dehydrobenzo[14]annulene Blades (2012)

A new class of propel- ler-shaped compound (4), which consisted of dehydrobenzo[14]annulene ([14]DBA) blades, as well as its naphtho homologues (5 and 6), have been prepared. Although NMR studies of compound 4 did not provide useful information regarding its conformation in solution, DFT calculations with different functionals and the 6-31G* basis set all indicated that the D(3)-symmetric structure was energetically more favorable than the C(2) conformer. From X-ray crystallographic analysis, it appeared that compound 4 adopted a propeller-shaped-, approximately D(3)-symmetric structure in the solid state, in which the [14]DBA blades were twisted substantially owing to steric repulsion between the neighboring benzene rings. On the contrary, in the case of compound 6, although the DFT calculations with the B3LYP functional predicted that the D(3)-symmetric conformation was more stable, calculations with the M05 and M05-2X functionals indicated that the C(2) conformer was more favorable because of π-π interactions between the naphthalene units of a pair of neighboring blades. Indeed, X-ray analysis of compound 6 showed that it adopted an approximately C(2)-symmetric conformation. Moreover, on the basis of variable-temperature (1)H NMR measurements, we found that compound 6 adopted a C(2) conformation and the barrier for interconversion between the C(2)-C(2) conformers was estimated to be 16.2 kcal mol(-1); however, no indication of the presence of the D(3) isomer was obtained. The relatively small energy barriers to interconversion, despite the large overlapping of neighboring blades, was ascribed to the flexibility of the acetylene linkages, which could be deformed substantially in the transition state of the ring-flip.