gebhart/patrepeval huggingface dataset:
Satellite ground stations with electronic beam steering (2012)

In this work, we propose electronic beam steering via antenna arrays as a substitute for large parabolic antennas at satellite ground stations. We concentrate on two array geometries, faceted arrays and hemispherical arrays. A thorough analysis is carried out of the radiation characteristics, the array size, as well as the antenna element distribution and spacing. Moreover, in order to fulfill the requirement of the array design, that is, to achieve a higher gain at low elevation angles where the longer spacecraft to ground station distance leads to a larger range loss, we propose to adjust the number of active antenna elements, i.e., some antenna elements are turned on while others are turned off according to the required level of antenna gain. This also contributes to a concept of an optimized array design for this specific application. In the simulations, the array optimization for both array geometries is further investigated and realized with a realistic ephemeris incorporated. The numerical results support the proposal of replacing large reflector antennas by electronic beam steering via antenna arrays at satellite ground stations.
Thrombospondin-1-Derived Peptide RFYVVMWK Improves the Adhesive Phenotype of CD34<sup>+</sup> Cells from Atherosclerotic Patients with Type 2 Diabetes (2016)

CD34+ progenitor cells are growing in use for vascular repair. However, in diabetic individuals with cardiovascular diseases, these cells have dysfunctional engraftment capabilities, which compromise their use for autologous cell therapy. The thrombospondin-1-derived peptide RFYVVMWK has previously been reported to stimulate cell adhesiveness through CD47 and integrin activation pathways. Our aim was to test whether RFYVVMWK preconditioning could modulate CD34+ cell phenotype and enhance its proadhesive properties in diabetic patients. Peripheral blood mononuclear CD34+ cells isolated from 40 atherosclerotic patients with type 2 diabetes (T2D; n = 20) or without (non-T2D; n = 20) were preconditioned with 30 μM RFYVVMWK or truncated peptide RFYVVM. CD34+ cell adhesion was assessed on a vitronectin-collagen matrix and on TNF-α or IL-1β-stimulated HUVEC monolayers. Adhesion receptors, platelet/CD34+ cell conjugates, and cell viability were analyzed by flow cytometry and confocal microscopy. RFYVVMWK increased the adhesion of T2D CD34+ cells by eightfold to the vitronectin-collagen matrix (p < 0.001) corresponding to a threefold increase compared to unstimulated non-T2D CD34+ cells. The peptide induced the formation of platelet/CD34+ conjugates and increased the expression of TSP-1, CD29, CD51/CD61, and CD62P in both T2D and non-T2D cells. However, RFYVVMWK treatment did not affect the viability/apoptosis of CD34+ progenitor cells. In conclusion, priming CD34+ cells with RFYVVMWK may enhance their vascular engraftment during autologous proangiogenic cell therapy.
Understanding organic thin film properties for microelectronic organic field-effect transistors and solar cells (2005)

The objective of this work is to understand how the thin film characteristics of p-type organic and polymer semiconductors affect their electronic properties in microelectronic applications. To achieve this goal, three main objectives were drawn out: (1) to create single-crystal organic field-effect transistors and measure the intrinsic charge carrier mobility, (2) to develop a platform for measuring and depositing polymer thin films for organic field-effect transistors, and (3) to deposit polythiophene thin films for inorganic-organic hybrid solar cells and determine how thin film properties effect device performance. &#13;\n\tPentacene single-crystal field-effect transistors (OFETs) were successfully manufactured on crystals grown via horizontal vapor-phase reactors designed for simultaneous ultrapurification and crystal growth. These OFETs led to calculated pentacene field-effect mobility of 2.2 cm2/Vs. During the sublimation of pentacene at atmospheric pressure, a pentacene disporportionation reaction was observed whereby pentacene reacted with itself to form a peripentacene, a 2:1 cocrystal of pentacene:6,13-dihydropentacene and 6,13-dihydropentacene. This has led to the proposal of a possible mechanism for the observed disproportionation reaction similar to other polyaromatic hydrocarbons, which may be a precursor for explaining the formation of graphite. &#13;\n\tSeveral silicon-based and PET-based field-effect transistor platforms were developed for the measurement of mobility of materials in the thin film state. These platforms were critically examined against one another and the single-crystal devices in order to determine the optimal device design for highest possible mobility data, both theoretically based on silicon technology and commercially based on individual devices on flexible substrates. Novel FET device designs were constructed with a single gate per device on silicon and PET as well as the commonly used common-gate device. It was found that the deplanarization effects and poor gate insulator quality of the individual gate devices led to lower overall performance when compared to the common gate approach; however, good transistor behavior was observed with field modulation.&#13;\n\tAdditionally, these thin films were implemented into inorganic-organic hybrid and purely organic solid-state photovoltaic cells. A correlation was drawn between the thin film properties of the device materials and the overall performance of the device. It was determined that each subsequent layer deposited on the device led to a planarization effect, and that the more pristine the individual layer, the better device performance. The hybrid cells performed at VOC = 0.8V and JSC = 55A/cm2.
Quantum wire networks with local<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:msub><mml:mi mathvariant="double-struck">Z</mml:mi><mml:mn>2</mml:mn></mml:msub></mml:math>symmetry (2005)

For a large class of networks made of connected loops, in the presence of an external magnetic field of half flux quantum per loop, we show the existence of a large local symmetry group, generated by simultaneous flips of the electronic current in all the loops adjacent to a given node. Using an ultralocalized single particle basis adapted to this local ${\mathbb{Z}}_{2}$ symmetry, we show that it is preserved by a large class of interaction potentials. As a main physical consequence, the only allowed tunneling processes in such networks are induced by electron-electron interactions and involve a simultaneous hop of two electrons. Using a mean-field picture and then a more systematic renormalization-group treatment, we show that these pair-hopping processes do not generate a superconducting instability, but they destroy the Luttinger liquid behavior in the links, giving rise at low energy to a strongly correlated spin-density-wave state.
Sorbitan Tristearate Layers at the Air/Water Interface Studied by Shear and Dilatational Interfacial Rheology (2005)

The shear and dilatational rheology of condensed interfacial layers of the water-insoluble surfactant sorbitan tristearate at the air/water interface is investigated. A new interfacial shear rheometer allows measurements in both stress- and strain-controlled modes, providing comprehensive interfacial rheological information such as the interfacial dynamic shear moduli, the creep response to a stress pulse, the stress relaxation response to a strain step, or steady shear curves. Our experiments show that the interfacial films are both viscoelastic and brittle in nature and subject to fracture at small deformations, as was supported by in-situ Brewster angle microscopy performed during the rheological experiments. Although any large-deformation test is destructive to the sample, it is still possible to study the linear viscoelastic regime if the deformations involved are controlled carefully. Complementary results for the dilatational rheology in area step compression/expansion experiments are reported. The dilatational behavior is predominantly elastic throughout the frequency spectrum measured, whereas the layers exhibit generalized Maxwell behavior in shear mode within a deformation frequency regime as narrow as two decades, indicating the presence of additional relaxation mechanisms in shear as opposed to expansion/compression. If the transient rheological response from stress relaxation experiments is considered, then the data can be described well with a stretched exponential model both in the shear and dilatational deformations.
Zoo- und Wildtiere (2020)

Einleitung In den vergangenen Jahren wurde in der Isar um München ein massiver Rückgang von Bachforellen in den Sommermonaten beobachtet. Betroffene Fische zeigten eine Schwarzfärbung der Haut und Apathie, vergleichbar dem Bachforellensterben-Syndrom (Proliferative Darkening Syndrome, PDS).
Multiple path planning using wavefront collision (2007)

The concept of wavefront expansion was introduced in order to build a collision-free path between two points among obstacles, minimizing a criterion. In this paper, we propose a new concept, called wavefront collision, in order to do the same for all possible paths between n waypoints. It consists in expanding simultaneously one wavefront by waypoint, until they collide. Using this concept, all paths can be computed thanks to one multiple wavefront expansion instead of n - 1, hence dividing the computational effort by about 3.5.
Broad Spectrum β-Lactamase Inhibition by a Thioether Substituted Bicyclic Boronate (2019)

β-Lactamases comprise the most widely used mode of resistance to β-lactam antibiotics. Cyclic boronates have shown promise as a new class of β-lactamase inhibitor, with pioneering potential to potently inhibit both metallo- and serine-β-lactamases. We report studies concerning a bicyclic boronate ester with a thioether rather than the more typical β-lactam antibiotic “C-6/C-7” acylamino type side chain, which is present in the penicillin/cephalosporin antibiotics. The thioether bicyclic boronate ester was tested for activity against representative serine- and metallo-β-lactamases. The results support the broad inhibition potential of bicyclic boronate based inhibitors with different side chains, including against metallo-β-lactamases from B1, B2, and B3 subclasses. Combined with previous crystallographic studies, analysis of a crystal structure of the thioether inhibitor with the clinically relevant VIM-2 metallo-β-lactamase implies that further SAR work will expand the already broad scope of β-lactamase inhibition by bicyclic boronates.
Growth Parameters of Yield of Plantain (Musa cv. AAB) (1985)

The performance of the crop plant and the ‘ratoon’ plant (lateral shoot succeeding the harvested main shoot) of 65 medium-sized False Horn plantains (Musa cv. AAB) was studied by measuring vegetative and inflorescence (bunch) parameters. From significant regressions between different parameters it appears that taller pseudostems produce leaves at a faster rate, flower earlier and produce heavier infructescences which need more time to mature. A high yield is determined by vigorous initial growth of the planted sucker (lateral root). Before flowering, there is no sink competition between ratoon and main pseudostem growth, and fast-growing main pseudostems are accompanied by fast-growing ratoons. After flowering, competition occurs between the fructifying inflorescence, a preferential sink and the ratoon. The results indicate that plantain should not be considered as an annual crop.
A case of Gitelman syndrome with normomagnesemia: do detailed history and basic laboratory tests provide correct diagnosis? (2015)

Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
Magnetic Resonance Imaging Guided Prostate Biopsy in Men With Repeat Negative Biopsies and Increased Prostate Specific Antigen (2009)

Multimodal magnetic resonance imaging is an effective technique to localize prostate cancer. Magnetic resonance imaging guided biopsy of tumor suspicious regions is an accurate method to detect clinically significant prostate cancer in men with repeat negative biopsies and increased prostate specific antigen.
New Antimalarial Drugs (2004)

Abstract For Abstract see ChemInform Abstract in Full Text.
Definitive Role of CT Scanning of the Pancreas (1977)

In a group of 188 patients, 192 computed tomographic (CT) scans of the pancreas were done, and the diagnostic accuracy of CT determined relative to other modalities. CT was the most effective method of detecting neoplastic and inflammatory disease. The full extent of the disease process, including involvement of the retroperitoneum and metastasis to the liver, was visualized with one examination. Calcification and cystic collections associated with pancreatitis were also clearly seen.
Mortality of Patients Suspended From the Kidney Transplant Waiting List in the UK. (2014)

Aim Mortality of patients active on the Kidney Transplant Waiting List (KTWL) is considered to be low; this may underestimate the true mortality of kidney transplant candidates as some may die after being suspended. We analysed outcome and survival of all Suspended Patients (SPt) from KTWL Method Using data from the UK Transplant Registry (1/1/2000-31/12/2008), we generated 3 Cohorts (Cht) Cht 1: all SPt for a period of >1 month irrespective of activation date Cht 2: all patients first registered in the study period with a suspension of >1 month. Patients censored at transplant or if alive and removed from KTWL. We analysed mortality and suspension rate and risk factors of suspension and survival after Deceased Donor Renal Transplant (DDRT) Cht 3: all patients within Cht 2 who survived >1yr from registration Follow up ≥5 yrs Data compared using Kaplan-Meyer for survivals and Cox Model for risk of suspension and death Results Cht 1:7516 SPt total, 2566(34%) died, 1125(15%) removed from KTWL. Age most important risk factor Cht 2:14283 activated patients total, 10493(74%) transplanted, 1192(8.3%) removed from KTWL Total SPt 6164(43%); 1494(24.2%) SPt died. Total Not Suspended Patients (NSPt) 8119 (56.8%); 641(8%) NSPt died Overall 2135 patients died in the study period(15%) Rate of SPt increased with years on KTWL.Table: No Caption available.Age and primary disease important risk factors for suspension 5yr survival after a DDRT showed no difference between SPt and NSPt; log-rank p=0.3 Cht 3: 5yr survival of SPt in first year was inferior to NSPt; log-rank p<0.0001.Figure: No Caption available.Conclusion Suspension is an important event in the life of a patient waiting for a kidney transplant affecting a substantial proportion of patients on the KTWL Mortality of patients waiting for a kidney transplant is higher than generally perceived when including SPt and the rate of suspension increases with time on KTWL. Survival benefit after DDRT similar between SPt and NSPt Suspension in first year associated with inferior survival Age and cause of renal failure important risk factors for death and suspension
Deep Active Latent Surfaces for Medical Geometries (2022)

Shape priors have long been known to be effective when reconstructing 3D shapes from noisy or incomplete data. When using a deep-learning based shape representation, this often involves learning a latent representation, which can be either in the form of a single global vector or of multiple local ones. The latter allows more flexibility but is prone to overfitting. In this paper, we advocate a hybrid approach representing shapes in terms of 3D meshes with a separate latent vector at each vertex. During training the latent vectors are constrained to have the same value, which avoids overfitting. For inference, the latent vectors are updated independently while imposing spatial regularization constraints. We show that this gives us both flexibility and generalization capabilities, which we demonstrate on several medical image processing tasks.
Structure of TiO<sub>2</sub> Nanorods Formed with Double Surfactants (2008)

Nanorod titania particles of anatase structure with 100 nm length and 20 nm width on an average were synthesized by a hydrothermal process with double surfactants system under relatively rigid tubular template in water. The rods have a tetragonal shape with washboard-like {101} surfaces, and covered properly with a Grätzel dye, exhibiting a high efficiency of light–to-electricity.
Factors affecting the post larval production of Macrobrachium rosenbergii (de man) by using different types of feeds (2013)

In the present study was conducted to know the importance of for the effects of different types of feed on larval survival of Macrobrachium rosenbergii .  In this experiment total nine tanks are selected and were divided, placed under three experiments ( Viz. E 1 , E 2 , and E 3 ) each having three replicates. The feshly hatched out larvae (Zoea) were collected and stocked in three different treatment tanks. The larvae were stoked in E 1 ( Artemia nauplii and egg custard), E 2 ( Artemia nauplii only) and E 3 (Freeze dried ( Cyclop-eeze only).  The survival rate of postlarvae found to vary from 5 to 40%. Highest rate of survival was recorded for the treatment of E 1 (31.5- 40.2 %) and the lowest survival was recorded in E 3 (3.0- 5.2 %). Such variations was occurred due to higher nutritive and growth promoting value of egg custard. The result obtained from the present study indicated that rearing of freshwater prawn larvae by improved management techniques can be considered economically viable and acceptable. So the production of post larvae of prawn was increased significantly by using Artemia nauplii and egg custard as larval diet.
Effect of FcRn antagonism on protective antibodies and to vaccines in IgG-mediated autoimmune diseases pemphigus and generalised myasthenia gravis (2022)

Antagonism of the neonatal Fc receptor (FcRn) by efgartigimod has been studied in several autoimmune diseases mediated by immunoglobulin G (IgG) as a therapeutic approach to remove pathogenic IgGs. Whereas reduction of pathogenic titres has demonstrated efficacy in multiple autoimmune diseases, reducing total IgG could potentially increase infection risk in patients receiving FcRn antagonists. The objective of this study was to analyse the effect of FcRn antagonism with efgartigimod on existing protective antibody titres and the ability to mount an immune response after vaccine challenge. Serum levels of total IgG and protective antibodies against tetanus toxoid (TT), varicella zoster virus (VZV), and pneumococcal capsular polysaccharide (PCP) were measured in all patients enrolled in an open-label trial of efgartigimod for the treatment of pemphigus. Vaccine specific-responses were assessed by measuring changes in IgG titres in patients with generalised myasthenia gravis (gMG) who were treated with efgartigimod and who received influenza, pneumococcal, or coronavirus disease 2019 (COVID-19) vaccines during participation in the double-blind trial ADAPT or open-label extension, ADAPT+ (<i>n</i> = 17). FcRn antagonism reduced levels of protective anti-TT, anti-VZV, and anti-PCP antibodies and total IgG to a similar extent; anti-TT and anti-VZV titres remained above minimally protective thresholds for the majority of patients, (10/12) 83% and (14/15) 93% respectively. Protective antibodies returned to baseline values upon treatment cessation. Antigen-specific IgG responses to influenza, pneumococcal, and COVID-19 immunisation were detected in patients with gMG who received these vaccines while undergoing therapy with efgartigimod. In conclusion, FcRn antagonism with efgartigimod did not hamper generation of IgG responses but did transiently reduce IgG titres of all specificities.
Post-Operative Lucency Formation Amongst Stemmed vs Non-Stemmed Total Ankle Arthroplasty Constructs (2022)

Category: Ankle Arthritis; Ankle; Hindfoot Introduction/Purpose: Current available total ankle replacement constructs offer either proximal projecting pegs (non- stemmed) in various shapes or large stem (stemmed) designs to the superior aspect of the tibia component. Each design offers inherent stability and unique function. Periprosthetic radiolucency can develop post-operatively and lead to adverse effects. However, the incidence and clinical significance of lucency formation amongst stemmed and non-stemmed constructs is poorly understood. Methods: A retrospective radiographic and chart analysis was performed of 256 patients, under a single orthopedic practice, who underwent primary TAA between 2013-2019 with one of 3 total ankle systems. Pre-operative ankle characteristics, intraoperative procedures, as well as post-operative angles, lucency formation, region of lucency formation, and patient outcomes were analyzed. Results: Patients' mean age 65.5 yrs., male n=126 and female n=127, a mean follow-up of 24.3 months for our patient cohort. A total of 149 stemmed and 107 non-stemmed constructs were analyzed. Incidence of periprosthetic tibial lucency formation 33.2%, stemmed implants 10.0%, and 65.4% for non-stemmed implant (p value 0.00001). Conclusion: This paper describes the incidence of periprosthetic formation amongst a stemmed and non-stemmed total ankle arthroplasty cohort. Statistical significance was found when analyzing stemmed vs. non-stemmed incidence of radiolucency formation, this did not correlate with increased incidence of post-operative complications.
Identifying intracellular signaling modules and exploring pathways associated with breast cancer recurrence (2021)

Exploring complex modularization of intracellular signal transduction pathways is critical to understanding aberrant cellular responses during disease development and drug treatment. IMPALA (Inferred Modularization of PAthway LAndscapes) integrates information from high throughput gene expression experiments and genome-scale knowledge databases to identify aberrant pathway modules, thereby providing a powerful sampling strategy to reconstruct and explore pathway landscapes. Here IMPALA identifies pathway modules associated with breast cancer recurrence and Tamoxifen resistance. Focusing on estrogen-receptor (ER) signaling, IMPALA identifies alternative pathways from gene expression data of Tamoxifen treated ER positive breast cancer patient samples. These pathways were often interconnected through cytoplasmic genes such as IRS1/2, JAK1, YWHAZ, CSNK2A1, MAPK1 and HSP90AA1 and significantly enriched with ErbB, MAPK, and JAK-STAT signaling components. Characterization of the pathway landscape revealed key modules associated with ER signaling and with cell cycle and apoptosis signaling. We validated IMPALA-identified pathway modules using data from four different breast cancer cell lines including sensitive and resistant models to Tamoxifen. Results showed that a majority of genes in cell cycle/apoptosis modules that were up-regulated in breast cancer patients with short survivals (< 5 years) were also over-expressed in drug resistant cell lines, whereas the transcription factors JUN, FOS, and STAT3 were down-regulated in both patient and drug resistant cell lines. Hence, IMPALA identified pathways were associated with Tamoxifen resistance and an increased risk of breast cancer recurrence. The IMPALA package is available at https://dlrl.ece.vt.edu/software/ .