gebhart/patrepeval huggingface dataset:
Analysis of the effect of imperfect fiber endfaces on the performance of extrinsic Fabry‐Perot interferometric optical fiber sensors (1996)

A systematic theoretical analysis of the effect of imperfect fiber endface cleaves on the performance of extrinsic Fabry-Perot inter- ferometric (EFPI) optical fiber sensors is presented. This analysis allows the prediction of the dynamic range of a sensor with greater confidence, and gives the tolerances of the mechanical instrument required to pre- pare the fiber endfaces. Good correlation with preliminary experimental results is also shown. © 1996 Society of Photo-Optical Instrumentation Engineers. Subject terms: fiber optic sensors; Fabry-Perot interferometer; endface imperfec- tions; dynamic range.
Nonlinear robust control and minimax team problems (1999)

The problem of robust stabilization of a linear system leads to the classical ℋ︁∞ control problem. The same analysis applied to a nonlinear system leads to the problem of ensuring via output feedback that a nonlinear operator be Lipshitz continuous, with a prescribed Lipshitz modulus. We show that, in the same way as the ℋ︁∞ control problem is equivalent to a minimax control problem, the Lipshitz modulus control problem can be approached via a minimax team decision problem. This motivates us to re-visit a class of the so-called ‘static’ team decision problems for nonlinear dynamical control systems. Because of the ‘static’ character, signaling plays no role in that case, which is important for the equivalence with the Lipshitz modulus control problem. We show that under some conditions, a certainty equivalence principle applies that yields a practical solution to the team problem at hand. To reach that conclusion we must first investigate a ‘partial team’ problem where one of the team members has all the information. Copyright © 1999 John Wiley & Sons, Ltd.
Observations of fluorescent aerosol–cloud interactions in the free troposphere at the Sphinx high Alpine research station, Jungfraujoch (2015)

Abstract. The fluorescent nature of aerosol at a high Alpine site was studied using a wide-band integrated bioaerosol (WIBS-4) single particle multi-channel ultra violet-light induced fluorescence (UV-LIF) spectrometer. This was supported by comprehensive cloud microphysics and meteorological measurements with the aims of cataloguing concentrations of bio-fluorescent aerosols at this high altitude site and also investigating possible influences of UV-fluorescent particle types on cloud–aerosol processes. Analysis of background free tropospheric air masses, using a total aerosol inlet, showed there to be a minor but statistically insignificant increase in the fluorescent aerosol fraction during in-cloud cases compared to out of cloud cases. The size dependence of the fluorescent aerosol fraction showed the larger aerosol to be more likely to be fluorescent with 80 % of 10 μm particles being fluorescent. Whilst the fluorescent particles were in the minority (NFl/NAll = 0.27±0.19), a new hierarchical agglomerative cluster analysis approach, Crawford et al. (2015) revealed the majority of the fluorescent aerosol were likely to be representative of fluorescent mineral dust. A minor episodic contribution from a cluster likely to be representative of primary biological aerosol particles (PBAP) was also observed with a wintertime baseline concentration of 0.1±0.4 L−1. Given the low concentration of this cluster and the typically low ice active fraction of studied PBAP (e.g. pseudomonas syringae) we suggest that the contribution to the observed ice crystal concentration at this location is not significant during the wintertime.
CT Angiographic Source Images Predict Outcome and Final Infarct Volume Better Than Noncontrast CT in Proximal Vascular Occlusions (2011)

CT angiography source image ASPECTS correlates better with baseline stroke severity, is a better predictor of final infarct extension, and independently predicts neurological outcome than noncontrast CT ASPECTS.
Differential Gene Expression in the Developing Lateral Geniculate Nucleus and Medial Geniculate Nucleus Reveals Novel Roles for Zic4 and Foxp2 in Visual and (2009)

Primary sensory nuclei of the thalamus process and relay parallel channels of sensory input into the cortex. The developmental processes by which these nuclei acquire distinct functional roles are not well understood. To identify novel groups of genes with a potential role in differentiating two adjacent sensory nuclei, we performed a microarray screen comparing perinatal gene expression in the principal auditory relay nucleus, the medial geniculate nucleus (MGN), and principal visual relay nucleus, the lateral geniculate nucleus (LGN). We discovered and confirmed groups of highly ranked, differentially expressed genes with qRT-PCR and in situ hybridization. A functional role for Zic4, a transcription factor highly enriched in the LGN, was investigated using Zic4-null mice, which were found to have changes in topographic patterning of retinogeniculate projections. Foxp2, a transcriptional repressor expressed strongly in the MGN, was found to be positively regulated by activity in the MGN. These findings identify roles for two differentially expressed genes, Zic4 and Foxp2, in visual and auditory pathway development. Finally, to test whether modality-specific patterns of gene expression are influenced by extrinsic patterns of input, we performed an additional microarray screen comparing the normal MGN to "rewired" MGN, in which normal auditory afferents are ablated and novel retinal inputs innervate the MGN. Data from this screen indicate that rewired MGN acquires some patterns of gene expression that are present in the developing LGN, including an upregulation of Zic4 expression, as well as novel patterns of expression which may represent unique processes of cross-modal plasticity.
Characterization of the Retinoid Binding Properties of the Major Fusion Products Present in Acute Promyelocytic Leukemia Cells (1997)

The bcr1- and bcr3- promyelocytic leukemia/retinoic acid receptor α (PML/RARα) are the two major fusion proteins expressed in acute promyelocytic leukemia (APL) patients. These proteins, which are present in different lengths of PML (amino acids 1-552 and 1-394, respectively), contain most of the functional domains of PML and RARα, bind all-trans-retinoic acid (t-RA), and act as t-RA–dependent transcription factors. T-RA is an effective inducer of clinical remission only in patients carrying the t(15; 17) and expressing the PML/RARα products. However, in APL patients achieving complete remission with t-RA therapy the bcr3-PML/RARα product has been found associated with a poorer prognosis than bcr1-PML/RARα. In the present study we have investigated the structural and functional properties of the bcr3-PML/RARα in comparison to the previously characterized bcr1-PML/RARα. In particular, we have measured the binding properties of the two endogenous ligands t-RA and 9-cis-RA to both of these isoforms. T-RA binding analysis of nuclear and cytosolic extracts prepared from bcr3-PML/RARα APL patients and from bcr3-PML/RARα COS-1 transfected cells indicates that this protein is present only as high-molecular-weight nuclear complexes. Using saturation binding assays and Scatchard analyses we found that t-RA binds with slightly less affinity to the bcr3-PML/RARα receptor than to bcr1-PML/RARα or RARα (Kd = 0.4 nmol/L, 0.13 nmol/L or 0.09 nmol/L, respectively). Moreover, two different high-affinity 9-cis-RA binding sites (Kd = 0.45 and 0.075 nmol/L) were detectable in the bcr3-PML/RARα product but not in the bcr1-PML/RARα product (Kd = 0.77 nmol/L). By competition binding experiments we showed that 9-cis-RA binds with higher specificity to the bcr3-PML/RARα isoform than to the bcr1-PML/RARα or RARα. Consistent with these data, the binding of 9-cis-RA to the bcr3-PML/RARα product resulted in increased transcriptional activation of the RA-responsive element (RARE) TRE, but not of the βRARE, in transiently transfected COS-1 cells. These results provide evidence indicating that preferential retinoid binding to the different PML/RARα products can be measured.
Impact of a "fast" scanner on image quality in pediatric computed tomography. (1980)

One hundred children varying in age from newborn through four years were studied without sedation or anesthesia using a three-second CT scanner. Satisfactory scans were obtained in 99. The elimination of the hazards and morbidity of intramuscular sedation more than compensated for the extra effort required to scan these youngsters without any preparation.
A Novel Traffic-aware Self-Coexistence in Multichannel IEEE 802.22 WRAN (2014)

IEEE 802.22 is the first worldwide standard for Cognitive Radio Network (CRN) that exploits white spaces of television broadcast. It is a standard for Wireless Regional Area Networks (WRANs) which enables broadband wireless access. In order to coexist between multiple overlapped WRAN cells a single channel self-coexistence mechanism is introduced in IEEE 802.22-2011 standard. Upon the increasing demand for customer promise equipments ’ (CPE) high throughput, supporting for multichannel operation is inevitable for upcoming 802.22b amendment. In this paper, we propose a novel traffic-aware self-coexistence for multichannel operation in 802.22 WRAN such that we try to reach CPEs ’ satisfactions.
Generalized dynamic-disorder transport rule with application to the study of temporal correlation effects (1988)

A new relation giving average transport behavior for dynamically disordered systems in terms of that for static disorder follows by considering the statistical growth of mean-square carrier displacement. The result is more widely applicable than the D(\ensuremath{\omega})\ensuremath{\rightarrow}D(\ensuremath{\omega}-i\ensuremath{\lambda}) analytic continuation rule (for average reinitialization rate \ensuremath{\lambda}) originally derived for bond percolation on a periodic lattice, and reproduces earlier results in appropriate limits, thereby showing the analytic continuation rule and other earlier results to apply more generally than previously demonstrated, applying for example to a continuous distribution of hopping rates, to nonperiodic arrays of sites, and to site percolation as well as bond percolation. Application to a study of temporal correlation between reinitialization events in a bond-percolation model shows these effects to be small but non-negligible, demonstrating the applicability of the previous analytic continuation rule as a reasonable approximation under conditions where temporal correlation makes it inexact.
Over-the-Air Test of Dipole and Patch Antenna Arrays at 28 GHz by Probing them in the Reactive Near-Field (2020)

A test concept for millimeter-wave antennas and antenna arrays using metallic probes inserted in the reactive near-field of the single radiating element is presented. Demonstrated for patch antennas and planar dipole antennas operating at 28 GHz, the transmission line probes are designed to avoid de-tuning of the antenna feed-point impedance. When applied to antenna arrays, the unwanted coupling to neighboring elements is shown to be suppressed by more than 10 dB, compared to the coupling with the antenna radiator under test. Therefore, parallel probing of several array radiator elements becomes possible. Additional aspects of the proposed technique are discussed.
Live demonstration: A batteryless CMOS ISFET array powered by body heat for real-time monitoring of bio-fluids (2017)

We demonstrate a low-power CMOS ISFET array for pH sensing which is powered by body-heat alone. Each pixel in the 3-by-3 array contains an ISFET operating in weak-inversion that detects changes in pH as a current and the average of all the pixels then modulates a ring oscillator. The overall power of the sensing and processing ASIC is at most 6 μW. The ASIC also contains a ISM band bespoke transmitter which transmits measurements wirelessly. Power is supplied by a network of thermoelectric generators attached to an elastic strap worn on the forearm. Commercial power management ICs then create a stable 1.2 V supply for the sensing array. The ASIC is mounted on a test PCB with the management circuitry.
GLENOID COMPONENT LOOSENING IN TOTAL SHOULDER ARTHROPLASTY: INTEREST OF A NEW METAL-BACKED COMPONENT DEVOTED TO REVISION SURGERY (2010)

Glenoid component loosening is a concern in long term outcome of total shoulder arthroplasty. Unfortunately revision of glenoid loosening remains very challenging regarding bone reconstruction and reimplantation of a glenoid component. A new design metal-back component (Arrow™) seems to get the procedure easier and lead to higly best clinical and radiological results than prior technics. It is a retrospective study of 34 patients operated on for isolated aseptic glenoid component loosening between 1997 and 2007. Glenoid bone loss based on a new classification was rated in 5 degrees. All patients were reviewed at a mean follow up of 34 months (from 12 to 89). Pre and post operatively Constant score and SST have been evaluated. Fluoroscopic views and CT scan have been performed for radiologic assesment. Mean delay for revision surgery was 58 months (from 28 to 134 months). 16 patients underwent only bone graft reconstruction. 18 patients underwent both bone reconstruction and glenoid implant reimplantation. Autolog bone graft (iliac crest) was used in 19 cases, allograft bone in 5 cases, and both autolog and dried bone substitutes in 10 cases. The glenoid component was an uncemented metal-backed in 11 cases, and a polyethylene cemented in 2 cases. The new metal-backed bone ingrowth component is composed with a keel and a winglet securing bone graft fixation and implant stability. For the all cohort Constant score improves of 21 points (from 35 to 56). Gain of pain and active motion is statiscally significative (p Revision of glenoid component depends on the glenoid bone stock specially about posterior defect. The use of cortical autolog bone graft and new metalback component allows better glenoid reconstruction, secure the stabiliy of the new gle and yields to goods clinical results restoring painless shoulder and function. Reimplantation of a glenoid component becomes an adequate procedure for total shoulder arthroplasty revision
Nuclear translocation of pro‐amphiregulin induces chemoresistance in gastric cancer (2012)

Amphiregulin (AR) is derived from a membrane-anchored form (proAR) by ectodomain shedding, and is a ligand that activates epidermal growth factor receptor (EGFR). We have recently shown that proAR translocates from the plasma membrane to the nucleus after truncation of 11 amino acids at the C-terminus, which is independent of the conventional EGFR signaling pathway. Although proAR immunoreactivity has reportedly been detected in the nucleus of cancer cells, its biological meaning has never been investigated. This study was performed to investigate the roles of proAR nuclear translocation in human gastric cancer. We constructed proAR truncated 11 amino acids at the C-terminus (proARΔC11) that spontaneously translocates to the nucleus, and established proARΔC11-expression regulatable gastric cancer cells (MKN45, MKN28) using the tet-off system. Using these cells, we found that proAR nuclear translocation significantly induced chemoresistance in vitro and in vivo. Analyzing the relationship between immunoreactive localization of proAR and the clinical outcome for 46 advanced gastric cancer cases treated with chemotherapy, median survival time was 311 days in 16 patients with AR-positive staining in the nucleus and 387 days in 30 patients with AR-negative staining (P < 0.05). The present study demonstrates that proAR nuclear translocation increases resistance to anti-cancer drugs, which might be associated with poor prognosis in human gastric cancer.
OBSERVATION OF THE $S_{3}(0)$ TRANSITION IN SOLID PARAHYDROGEN AND THE DEVELOPMENT OF A THEORY OF $\Delta J=2$ ROVIBRATIONAL LINEWIDTHS. (1994)

Author Institution: The University of Chicago
3-2-1 contact (2010)

45 nm technology has brought another beast to fight against, i.e., the contact resistance. While in 65 nm less than 4% impact on device current was present, higher contact resistance in 45 nm has raised this value to 10%. 32 nm and 22 nm will show increased impact. To remedy this problem, contact bars (trenches) and contact-level routing are also used. In this paper, we provide 45 nm silicon results and draw attention to the contact resistance problem and show ways to overcome this problem. We supplement our silicon data with TCAD simulations as well as circuit analysis of contact bars and contact-level routing for a ring oscillator we have designed. We provide a library mapping methodology for contact routes. Proposed test structures, methodologies, and modeling scheme provide a direction towards tackling the contact resistance problem in 45 nm and below.
ChemInform Abstract: PREPARATION OF N‐ARYLMETHYLGLYCINATOBIS(ETHANE‐1,2‐DIAMINE)COBALT(III) COMPLEXES. COMPARISON OF THEIR EXCHANGE REACTIONS AT PD 9.7 (1982)

Abstract Die diamagnetischen Co(III)‐ Titelkomplexe (I) werden als Dichloride durch Umsetzung von trans‐Dichlor‐bis‐[ethylendiamin]‐Co(III)‐chlorid mit den entsprechenden Aminosäuren in Methanol in Gegenwart von LiOH synthetisiert.
Metal-decorated graphene oxide for ammonia adsorption (2013)

Based on the first-principles density functional theory, we have studied the stability, electronic structure and ammonia storage capacity of metal-decorated graphene oxide (GO). Metal atoms (Mg and Li) are bonded strongly to the epoxy oxygen atoms on the surface of the GO sheet, which can act as high-surface-area adsorbent for the ammonia uptake and release. Each metal atom can bind several ammonia molecules around itself with a reasonable binding energy. We find metal-decorated GO can store up to tens of moles of ammonia per kilogram, which is far better than the recently reported excellent ammonia adsorption by GO.
Coherent quantum annealing in a programmable 2000-qubit Ising chain (2022)

Quantum simulation has emerged as a valuable arena for demonstrating and understanding the capabilities of near-term quantum computers. Quantum annealing has been used successfully in simulating a range of open quantum systems, both at equilibrium and out of equilibrium. However, in all previous experiments, annealing has been too slow to simulate a closed quantum system coherently, due to the onset of thermal effects from the environment. Here we demonstrate coherent evolution through a quantum phase transition in the paradigmatic setting of the 1D transverse-field Ising chain, using up to 2000 superconducting flux qubits in a programmable quantum annealer. In large systems we observe the quantum Kibble-Zurek mechanism with theoretically predicted kink statistics, as well as characteristic positive kink-kink correlations, independent of system temperature. In small chains, excitation statistics validate the picture of a Landau-Zener transition at a minimum gap. In both cases, results are in quantitative agreement with analytical solutions to the closed-system quantum model. For slower anneals we observe anti-Kibble-Zurek scaling in a crossover to the open quantum regime. These experiments demonstrate that large-scale quantum annealers can be operated coherently, paving the way to exploiting coherent dynamics in quantum optimization, machine learning, and simulation tasks.
Performance Enhancement of Photocatalytic Reactor Utilizing Flow Instability (2003)

A detailed analysis has been performed for a heterogeneous photocatalytic Taylor vortex reactor that uses flow instability to recirculate fluid continually from the vicinity of the rotating inner cylindrical surface (coated with catalyst) to the stationary outer cylindrical surface of an annulus. A detailed time accurate computation when the reactor is started impulsively shows the different stages of flow evolution and the effects of finite length of the reactor in creating eddies, the overall effects of which shows very high efficiency of photocatalytic conversion. The physical arrangement considered is such that pollutant degradation is maximized by a combination of the controlled periodic illumination effect and the motion of fluid particles in a specific regime of centrifugal instability. It was found out that optimum Reynolds's number is 380 as the system reaches steady state faster, number of vortices per unit length is more, vortices move faster towards center from end, and the magnitude of both axial and radial component of velocity is more than at higher or lower value of Reynolds's number.
Acylations of pentafluorosulfanylamine, SF5NH2 (1982)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAcylations of pentafluorosulfanylamine, SF5NH2Joseph S. Thrasher, Jon L. Howell, and Alan F. CliffordCite this: Inorg. Chem. 1982, 21, 4, 1616–1622Publication Date (Print):April 1, 1982Publication History Published online1 May 2002Published inissue 1 April 1982https://pubs.acs.org/doi/10.1021/ic00134a068https://doi.org/10.1021/ic00134a068research-articleACS PublicationsRequest reuse permissionsArticle Views225Altmetric-Citations19LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Clustered Mutations in Yeast and in Human Cancers Can Arise from Damaged Long Single-Strand DNA Regions (2020)

Mutations are typically perceived as random, independent events. We describe here non-random clustered mutations in yeast and in human cancers. Genome sequencing of yeast grown under chronic alkylation damage identified mutation clusters that extend up to 200 kb. A predominance of “strand-coordinated” changes of either cytosines or guanines in the same strand, mutation patterns and genetic controls indicated that simultaneous mutations were generated by base alkylation in abnormally long single-strand (ss)DNA formed at double-strand breaks (DSBs) and replication forks. Significantly, we found mutation clusters with analogous features in sequenced human cancers. Strand-coordinated clusters of mutated cytosines or guanines often resided near chromosome rearrangement breakpoints and were highly enriched with a motif targeted by APOBEC family cytosine-deaminases, which strongly prefer ssDNA. These data indicate that hyper-mutation via multiple simultaneous changes in randomly formed ssDNA is a general phenomenon that may be an important mechanism producing rapid genetic variation.