gebhart/patrepeval huggingface dataset:
Subjective time compression induced by continuous action (2021)

Increasing evidence indicates that voluntary actions can modulate the subjective time experience of its outcomes to optimize dynamic interaction with the external environment. In the present study, using a temporal reproduction task where participants reproduced the duration of an auditory stimulus to which they were previously exposed by performing different types of voluntary action, we examined how the subjective time experience of action outcomes changed with voluntary action types. Two experiments revealed that the subjective time experience of action outcomes was compressed, compared with physical time, if the action was performed continuously (Experiment 1), possibly enhancing the experience of controlling the action outcome, or if the action was added an extra task-unrelated continuous action (Experiment 2), possibly reflecting different underlying mechanisms from subjective time compression induced by the task-related continuous action. The majority of prior studies have focused on the subjective time experience of action outcomes when actions were performed voluntarily or not, and no previous study has examined the effects of differences in voluntary action types on the subjective time experience of action outcomes. These findings may be useful in situations in which people wish to intentionally compress their own time experience of daily events through their voluntary actions.
A Hybrid Filter-based and Graph-based approach to SLAM (2010)

International audience
Metal Dissolution Kinetics in Aluminum Etch Tunnels (2000)

The potential dependence of the metal dissolution current density of aluminum in etch tunnels was measured, using pulsed increases of current during galvanostatic etching experiments. Etching was carried out in 1 N HCl solution at 65°C, and was followed by analysis of the topographic development of the dissolving surfaces using scanning electron microscopy. By manipulation of the current waveform, the dissolving area and the applied current were varied independently. Parallel experiments with current interruptions were used to help identify the area of the dissolving surfaces during the anodic pulse, which were shown to be submicron size patches on the tunnel tip surfaces. After correction for solution‐phase potential drops, the current was found to obey an exponential Tafel dependence on potential. Measurements of the dissolved depth vs. time show that the rate of cathodic hydrogen evolution is significantly increased during the anodic pulse, by comparison with that at the more negative potentials during constant current etching. Good agreement of the present current‐potential relation was obtained with that derived from the measurements of pit currents in thin films by Frankel et al. [J. Electrochem. Soc., 143, 1834 (1996)]. © 2000 The Electrochemical Society. All rights reserved.
Automated 96-Well SPE and LC−MS−MS for Determination of Protease Inhibitors in Plasma and Cartilage Tissues (2000)

Bioanalytical methods based on automated solid-phase extraction (SPE) and high-performance liquid chromatography with electrospray tandem mass spectrometry (LC-MS-MS) have been developed and utilized for the determination of MMP inhibitors in plasma and cartilage tissues. The SPE methods were automated using a 96-well extraction plate and a 96-channel programmable liquid-handling workstation. The LC-MS-MS methods were developed using a rapid gradient LC separation, followed by sample introduction through an ionspray interface in the positive ion mode and tandem mass spectrometric detection with selected reaction monitoring. In the optimized SPE methods, crude plasma or ground cartilage supernatant samples were loaded onto an SPE plate to remove proteins and other interfering components in the matrixes to render relatively clean extracts for LC-MS-MS analysis. Compared to the simple plasma protein precipitation method, the automated SPE method afforded significant time-saving in sample preparation and improved sensitivity in MS detection. The methods were validated and successfully applied to the analysis of protease inhibitors in plasma and cartilage tissues.
Effect of external electric field on the microstructural evolution of La<sub>2</sub>O<sub>3</sub>-doped BaTiO<sub>3</sub>ceramics (2005)

Abstract The grain growth behavior of La-doped BaTiO3 specimens was investigated at 1350 °C under DC external electric field. In air atmosphere, grain growth was enhanced at the positive-biased region for the 0.15 mol% La-doped and 0.3 mol% La-doped specimens, while it was enhanced at the negative-biased region for the 1.0 mol% La-doped specimen. For the 0.6 mol% La-doped specimen, on the other hand, both positive- and negative-biased regions showed the same grain size. The demarcation donor composition (0.6 mol% La) shifted to a higher donor concentration when the specimen was heat-treated in nitrogen. The results were explained in terms of the grain boundary potential and its variation with donor concentration, oxygen partial pressure, and defect polarization.
<i>SLC9A9</i>Co‐expression modules in autism‐associated brain regions (2016)

SLC9A9 is a sodium hydrogen exchanger present in the recycling endosome and highly expressed in the brain. It is implicated in neuropsychiatric disorders, including autism spectrum disorders (ASDs). Little research concerning its gene expression patterns and biological pathways has been conducted. We sought to investigate its possible biological roles in autism-associated brain regions throughout development. We conducted a weighted gene co-expression network analysis on RNA-seq data downloaded from Brainspan. We compared prenatal and postnatal gene expression networks for three ASD-associated brain regions known to have high SLC9A9 gene expression. We also performed an ASD-associated single nucleotide polymorphism enrichment analysis and a cell signature enrichment analysis. The modules showed differences in gene constituents (membership), gene number, and connectivity throughout time. SLC9A9 was highly associated with immune system functions, metabolism, apoptosis, endocytosis, and signaling cascades. Gene list comparison with co-immunoprecipitation data was significant for multiple modules. We found a disproportionately high autism risk signal among genes constituting the prenatal hippocampal module. The modules were enriched with astrocyte and oligodendrocyte markers. SLC9A9 is potentially involved in the pathophysiology of ASDs. Our investigation confirmed proposed functions for SLC9A9, such as endocytosis and immune regulation, while also revealing potential roles in mTOR signaling and cell survival.. By providing a concise molecular map and interactions, evidence of cell type and implicated brain regions we hope this will guide future research on SLC9A9. Autism Res 2017, 10: 414-429. © 2016 International Society for Autism Research, Wiley Periodicals, Inc.
Design, implementation and testing of extended and mixed precision BLAS (2002)

This article describes the design rationale, a C implementation, and conformance testing of a subset of the new Standard for the BLAS (Basic Linear Algebra Subroutines): Extended and Mixed Precision BLAS. Permitting higher internal precision and mixed input/output types and precisions allows us to implement some algorithms that are simpler, more accurate, and sometimes faster than possible without these features. The new BLAS are challenging to implement and test because there are many more subroutines than in the existing Standard, and because we must be able to assess whether a higher precision is used for internal computations than is used for either input or output variables. We have therefore developed an automated process of generating and systematically testing these routines. Our methodology is applicable to languages besides C. In particular, our algorithms used in the testing code will be valuable to all other BLAS implementors. Our extra precision routines achieve excellent performance---close to half of the machine peak Megaflop rate even for the Level 2 BLAS, when the data access is stride one.
Supplementary Methods, Figures, Tables, and References from Characterization of &lt;i&gt;KRAS&lt;/i&gt; Rearrangements in Metastatic Prostate Cancer (2023)

Supplementary Methods, Figures, Tables, and References from Characterization of &lt;i&gt;KRAS&lt;/i&gt; Rearrangements in Metastatic Prostate Cancer
Noninvasive <i>in Situ</i> Evaluation of Osteogenic Differentiation by Time-Resolved Laser-Induced Fluorescence Spectroscopy (2004)

The clinical implantation of bioengineered tissues requires an in situ nondestructive evaluation of the quality of tissue constructs developed in vitro before transplantation. Time-resolved laser-induced fluorescence spectroscopy (TR-LIFS) is demonstrated here to noninvasively monitor the formation of osteogenic extracellular matrix (ECM) produced by putative stem cells (PLA cells) derived from human adipose tissue. We show that this optical spectroscopy technique can assess the relative expression of collagens (types I, III, IV, and V) within newly forming osteogenic ECM. The results are consistent with those obtained by conventional histochemical techniques (immunofluorescence and Western blot) and demonstrate that TR-LIFS is a potential tool for monitoring the expression of distinct collagen types and the formation of collagen cross-links in intact tissue constructs.
CW intracavity frequency doubled Nd:YAG core ceramics composite at 473 nm (2014)

Get PDF Email Share Share with Facebook Tweet This Post on reddit Share with LinkedIn Add to CiteULike Add to Mendeley Add to BibSonomy Get Citation Copy Citation Text G. Aka, L. Zheng, A. Ikesue, Y. L. Aung, and P. Loiseau, "CW intracavity frequency doubled Nd:YAG core ceramics composite at 473 nm," in Advanced Solid State Lasers, OSA Technical Digest (online) (Optica Publishing Group, 2014), paper AM4A.3. Export Citation BibTex Endnote (RIS) HTML Plain Text Citation alert Save article
Measurement of blood flow through surgical anastomosis using the radioactive microsphere technique. (1985)

Two different radioactive microspheres (141Ce and 46Sc) were used to measure blood flow to an area of the large intestine in dogs before and after a surgical resection was performed with surgical staples. The healing of an anastomosis is theoretically related to the blood flow to the anastomotic site. Blood flow studies were conducted in three dogs using this technique. The average blood flow preoperatively was 0.558 mL/minute per gram and 1.04 mL/minute per gram postoperatively. The standard deviation was +/- 0.16. These results indicate a statistically significant (P less than .05) increase in blood flow at the anastomotic site six days after anastomosis when compared with the blood flow to the same area before any surgical procedures.
Advanced dispersion measurement techniques for the characterization of the mechanical properties of poro-visco-elastic materials (2013)

Dispersion measurement techniques are normally used to determine the mechanical properties of poro-visco-elastic materials, such as their shear modulus. However, dispersion measurements of poro-visco-elastic materials are not easy and the experimentally accessible frequency range in which the modes of propagation are detectable is limited to the lower frequency range, typically up to about 1500 Hz. In this article an advanced measurement technique is discussed to perform the dispersion measurement, allowing to capture reliable measurement data up to higher frequencies and for higher order modes of propagation. A typical measurement result using the proposed approach is shown and the results are compared briefly with numerical simulations.
Pathological Feature and Immunoprofile of Cystitis Glandularis Accompanied with Upper Urinary Tract Obstruction (2014)

It is suggested that glandular cystitis accompanied with upper urinary tract obstruction shares the same pathological feature and immunoprofile as that without upper urinary tract obstruction. No significant differences of immunohistochemical expression in tissue are in cystitis glandularis with different pathological types.
Effect of a metallic gate on the energy levels of a shallow donor (2008)

We have investigated the effect of a metallic gate on the bound states of a shallow donor located near the gate. We calculate the energy spectrum as a function of the distance between the metallic gate and the donor and find an anticrossing behavior in the energy levels for certain distances. We show how a transverse electric field can tune the average position of the electron with respect to the metallic gate and the impurity.
(p,n) systematics and the cosmological connection (1987)

Inclusive measurements of (p,n) reactions at intermediate energies of 50 to 1000 MeV have yielded new information in recent years on the energy and target mass dependence for direct interactions in (p,n) reactions. Furthermore, central collision processes can add appreciably to the inelastic cross-section at intermediate energy producing intermediate mass fragments (IMF) in substantial yields at energies above 200 MeV. These systematics are of much value for interpreting cosmic-ray exposure times, alteration of elemental abundances, and cosmological processes. 59 refs., 4 figs.
Evaluation of Acoustic Channel Capacity for Complex Piping Topology (2019)

Transmission of information using elastic waves on existing metallic pipes provides an alternative communication option for a nuclear facility. The advantages of this approach consist of transmitting information through physical barriers, such as the containment building wall. In addition, this approach provides physical cybersecurity since the pipe becomes an analog communication channel which is difficult to eavesdrop on and difficult to sever. In prior work, a laboratory bench-scale system consisting of a six foot-long straight section of nuclear grade stainless steel pipe and high-temperature ultrasonic LiNbO<sub>3</sub> transducers was assembled. The lab systems was used for communication protocol development and preliminary data transmission demonstration. Next phase of project development involves deployment of the ultrasonic communication system in a representative environment. Mechanisms Engineering Test Loop (METL) facility at ANL was chosen as a viable candidate for communication system demonstration. Analysis of piping manifolds at METL has shown that in a typical scenario, ultrasonic signals have to be transmitted over straight and bent piping sections. This report describes preliminary studies on transmission of information with ultrasonic shear waves across bent piping sections. A test article consisting of a stainless steel pipe bent at 90° was developed for laboratory analysis of ultrasonic signal transmission. The bent piping test article developed by welding two straight pipes to an elbow. For consistency, the diameter and wall thickness of the bent pipe is the same as that of the straight pipe utilized in prior studies. COMSOL computer simulations were performed to study ultrasonic refracted shear wave coupling and transmission across bent piping. Preliminary evaluations of ultrasonic shear wave transmission were conducted with piezoelectric (PZT) and LiNbO<sub>3</sub> transducers, with the signals recorded with previously developed LabView interface. Preliminary results have shown significant dispersion of transmitted signals, most likely due to reflections and scattering by piping welds. Signal distortion compensation algorithm based on time reversal modulation (TRM) was initially investigated for transmission through solids, and demonstrated for signals transmitted over the bent pipe. Using TRM, it was shown that communication bitrates of 100Kbps were achievable, in principle.
Cellular Uptake of Ribonuclease A Relies on Anionic Glycans (2010)

Bovine pancreatic ribonuclease (RNase A) can enter human cells, even though it lacks a cognate cell-surface receptor protein. Here, we report on the biochemical basis for its cellular uptake. Analyses in vitro and in cellulo revealed that RNase A interacts tightly with abundant cell-surface proteoglycans containing glycosaminoglycans, such as heparan sulfate and chondroitin sulfate, as well as with sialic acid-containing glycoproteins. The uptake of RNase A correlates with cell anionicity, as quantified by measuring electrophoretic mobility. The cellular binding and uptake of RNase A contrast with those of Onconase, an amphibian homologue that does not interact tightly with anionic cell-surface glycans. As anionic glycans are especially abundant on human tumor cells, our data predicate utility for mammalian ribonucleases as cancer chemotherapeutic agents.
Kinetic and thermodynamic azides from α-triflates of γ-lactones: intermediates for the incorporation of polyhydroxylated<scp>D</scp>- and<scp>L</scp>-α-aminoacids into combinatorial libraries (1996)

Displacement of α-triflates of 2,3,4-all cis-substituted γ-lactones by sodium azide in DMF gives kinetically an azide with inversion of configuration at the C-2 of the lactone; under the reaction conditions, the initially formed azide epimerises to the apparently more crowded and thermodynamically stable all cis-azide, giving intermediates which should readily allow the incorporation of polyhydroxylated amino acids into combinatorial libraries.
Electrospray Ionization Mass Spectrometric Analyses of Phospholipids from Rat and Human Pancreatic Islets and Subcellular Membranes:  Comparison to Other Tissues and Implications for Membrane Fusion in Insulin Exocytosis (1998)

Glucose-induced insulin secretion from pancreatic islets involves hydrolysis of arachidonic acid from phospholipids as an intermediary event. Accumulation of nonesterified arachidonate in islet membranes may influence both ion fluxes that trigger insulin secretion and fusion of secretory granule and plasma membranes. Recent findings indicate that plasmenylethanolamine species may also participate in fusion of such membranes, but high-performance liquid chromatographic (HPLC) and gas chromatographic/mass spectrometric (GC/MS) analyses of islet secretory granule phospholipids suggested that they contain little plasmenylethanolamine. Here, electrospray ionization mass spectrometry (ESI/MS) of intact phospholipid molecules is used to demonstrate that the most prominent components of all major glycerophospholipid headgroup classes in islets are arachidonate-containing species. Such species contribute the majority of the ESI/MS negative ion current from rat and human islet glycerophosphoethanolamine (GPE), and the fraction of GPE negative ion current contributed by plasmenylethanolamine species in rat islets is higher than that for rat liver or heart and similar to that for brain. The most prominent sn-2 substituent of plasmenylethanolamine species in brain is docosahexaenoate and in islets is arachidonate. Arachidonate-containing plasmenylethanolamine species are also prominent components of GPE from islet secretory granules and plasma membranes. Fusion of islet secretory granule and plasma membranes is demonstrated to be catalyzed by cytosolic components from insulinoma cells and rat brain with chromatographic similarities to a rabbit brain factor that specifically catalyzes fusion of plasmenylethanolamine-containing membranes.
Supplementary Figure Legend from The Relationship Between Homologous Recombination Repair and the Sensitivity of Human Epidermis to the Size of Daily Doses Over a 5-Week Course of Breast Radiotherapy (2023)

&lt;p&gt;PDF file, 48K.&lt;/p&gt;
Equation-Error Model Based Active Noise Cancellation Systems (2019)

The filtered-U recursive least mean square (FURLMS) algorithm for active noise control (ANC) system is derived according to the output-error (OE) model based adaptive infinite impulse response (IIR) filter. This paper develops the ANC system by using the equation-error (EE) model based adaptive IIR filter. Since the weighting vectors in the mean square error (MSE) of the EE model baesd filter is a quadratic function, the EE model is guaranteed to reach the global minimum of MSE by properly choosing the step size. This paper also derives the proposed EE model based ANC system is identical to the hybrid ANC system. Simulation results show the effectiveness of the proposed algorithm.
Linearised InGaP/GaAs HBT MMIC power amplifierwith active bias circuit for W-CDMA application (2001)

A high linearity InGaP/GaAs heterojunction bipolar transistor (HBT) monolithic microwave integrated circuit (MMIC) power amplifier is demonstrated using a new structure for a bias circuit for wideband-code division multiple access (W-CDMA) application. A one shunt capacitor is added to a novel active bias circuit and acts as a lineariser improving input P1dB of 16 dB and phase distortion of 5.1° for the hybrid phase shift keying (HPSK) modulated signal at the 28 dBm output power; the lineariser showing no significant increase of signal loss and chip area. The two-stage HBT MMIC amplifier exhibits a power-added efficiency (PAE) of 37%, a linear power gain of 24.5 dB, and an output power of 28 dBm with an adjacent channel power ratio (ACPR) of –45 dBc, under a 3 V operation voltage.
Classical Analysis of the Bending of Beams (2011)

This chapter contains sections titled: Introduction Area Properties—Sign Conventions Derivation and Solution of the Governing Equations The Statically Determinate Case Work and Energy—Castigliano's Second Theorem The Statically Indeterminate Case Solutions from the Theory of Elasticity Variable Cross Sections Shear Stress in Non Rectangular Cross Sections—Thin Walled Cross Sections Design of Beams Large Displacements Summary and Conclusions
Neuromedin U Induces Pulmonary Group 2 Innate Lymphoid Cell Activation via NMUR1 Pathway During Acute Respiratory Syncytial Virus Infection (2021)

Abstract Background： The activated group 2 innate lymphocytes (ILC2s) play a crucial role in respiratory syncytial virus (RSV)-induced airway inflammation by secreting large amount of type 2 cytokines. Although the classical activator IL-33 is the key factor for ILC2 activation, a regulatory effect of neurotransmitter-neuromedin U (NMU) has also been reported. However, whether and how NMU can be elicited by RSV infection and regulate pulmonary ILC2 activation remains unclear. Methods： The regulatory effect and underlying mechanisms of NMU on ILC2 activation were determined by using RSV-infected wild-type and NMU-knockout mice. The expression of NMU in the lungs and NMUR1 on ILC2s were measured by Real-time PCR and Western blot. Flow cytometry and ELISA were used to detect the proliferation and activation of ILC2s. The type of neurons secreting NMU and its possible secretion mechanism during RSV infection were also analyzed. Results： Acute RSV infection induced the production of NMU in the lungs of mice and up-regulate the expression of NMUR1 on the pulmonary ILC2s. In vivo administration of NMU exacerbated RSV-induced airway inflammation by promoting the proliferation and activation of pulmonary ILC2s via NMUR1 pathway. In this process, PI3K, MEK and NFAT signal proteins might be involved. Furthermore, pulmonary neurons responded to the stimulation of RSV and secreted NMU in TLR4 and TLR7-dependent manners. Conclusion： Our data suggest that NMU is an ILC2 activator other than the classical activator, revealing a novel effect of neurotransmitter on RSV-induced airway inflammation.