gebhart/patrepeval huggingface dataset:
Maleimide Self-Reaction in Furan/Maleimide-Based Reversibly Crosslinked Polyketones: Processing Limitation or Potential Advantage? (2021)

Polymers crosslinked via furan/maleimide thermo-reversible chemistry have been extensively explored as reprocessable and self-healing thermosets and elastomers. For such applications, it is important that the thermo-reversible features are reproducible after many reprocessing and healing cycles. Therefore, side reactions are undesirable. However, we have noticed irreversible changes in the mechanical properties of such materials when exposing them to temperatures around 150 °C. In this work, we study whether these changes are due to the self-reaction of maleimide moieties that may take place at this rather low temperature. In order to do so, we prepared a furan-grafted polyketone crosslinked with the commonly used aromatic bismaleimide (1,1'-(methylenedi-4,1-phenylene)bismaleimide), and exposed it to isothermal treatments at 150 °C. The changes in the chemistry and thermo-mechanical properties were mainly studied by infrared spectroscopy, <sup>1</sup>H-NMR, and rheology. Our results indicate that maleimide self-reaction does take place in the studied polymer system. This finding comes along with limitations over the reprocessing and self-healing procedures for furan/maleimide-based reversibly crosslinked polymers that present their softening (decrosslinking) point at relatively high temperatures. On the other hand, the side reaction can also be used to tune the properties of such polymer products via in situ thermal treatments.
Electronic properties of single- and double-MoFe3S4 cubane-type clusters (1983)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTElectronic properties of single- and double-MoFe3S4 cubane-type clustersP. K. Mascharak, G. C. Papaefthymiou, W. H. Armstrong, S. Foner, R. B. Frankel, and R. H. HolmCite this: Inorg. Chem. 1983, 22, 20, 2851–2858Publication Date (Print):September 1, 1983Publication History Published online1 May 2002Published inissue 1 September 1983https://doi.org/10.1021/ic00162a017RIGHTS & PERMISSIONSArticle Views233Altmetric-Citations42LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (980 KB) Get e-Alertsclose Get e-Alerts
Less Becomes More for Microwave Imaging: Design and Validation of an Ultrawide-Band Measurement Array (2017)

A compact, enclosed, ultrawide-band (UWB) antenna array is presented to acquire data for a quantitative microwave imaging method. Compared to existing systems, the proposed array allows a UWB antenna to be placed close to a target object while, at the same time, minimizing the volume of the imaging array. The antennas and metallic enclosure are designed to easily integrate with an iterative threedimensional (3-D) nonlinear inverse scattering technique. The volume of the internal imaging domain has been minimized for this particular architecture to reduce the computational time spent on reconstructing the dielectrics within the domain. Each cavity-backed element radiates toward the target and presents stable transmission characteristics across the 1-4-GHz band.
[Experimental study on the retinal tear. 1. Scanning electron microscopic observation of the retinal tear after long term observation (author's transl)]. (1978)

Telecom equipment is composed of hardware and software components.\nAdditionally, the test related software on the module, board and system level\nbecomes a bigger relative part of the entire software content. This part gains\nimportance as verification and integration complexity stays increasing at a\nhigh rate. This paper describes the characteristics of the embedded SW and\nmore particularly of the hardware dependent software (HdS) design domain in\ntelecom equipment, optimized for reusability, scalability and portability. A\nbasic framework in UML of a generic hardware abstraction layer, from which\nan HdS platform can be instantiated for any such telecom system, is proposed.
Liquid Chromatography–High-Resolution Mass Spectrometry (LC-HRMS) Profiling of Commercial Enocianina and Evaluation of Their Antioxidant and Anti-Inflammatory Activity (2022)

Enocianina is an anthocyanin-rich extract obtained from grape pomace. It is widely used as a colorant in the food industry and, in addition to anthocyanins, it also contains a variety of polyphenols. To understand whether enocianina, besides its coloring effect, may offer potential health benefit applications, we aimed to fully characterize the profile of four commercial enocianinas and assess their radical scavenging, enzymatic, antioxidant, and anti-inflammatory activities. LC-ESI-MS/MS analysis identified 90 phytochemicals. The relative content of each anthocyanin was assessed by a semi-quantitative analysis, with malvidin derivatives being the most abundant. UV-VIS spectroscopy detected total amounts of polyphenols and anthocyanins of 23% and 3.24%, respectively, indicating that anthocyanins represent a minor fraction of total polyphenols. Multiple linear regression analysis indicated that the radical scavenging activity is related to the total polyphenol content and not to anthocyanins. All four enocianinas dose-dependently activate Nrf2, and such activity was correlated with catechol-containing polyphenol content. Finally, all enocianinas showed dose-dependent anti-inflammatory activity, which at the highest concentrations tested was closely related to the total polyphenol content and was explained by radical scavenging, Nrf2 activation, and other mechanisms related to the polyphenolic components.
Light beating spectroscopy of Brillouin scattering in gases and solids (2006)

The experimental system of optical beating spectroscopy was improved, and the increased sensitivity and frequency resolution were demonstrated in the Brillouin scattering experiments in solids, crown glass (BK7), and polymethylmetacrylate (PMMA), and also in gases, air, and nitrogen. For their weak light scattering ability, these substances are very tough specimens for Brillouin scattering studies, and the classical spectrometer of Fabry-Pérot étalon has been so far used for the frequency analysis. The phonon peaks were observed with the present light beating system in BK7 at room temperature over the wave number range from k∕2π=1.03×104to8.84×104m−1 (corresponding frequency from 61.6to548MHz), and the spectra were fitted with Gaussian curves since a condenser lens in the incident light path caused a large instrumental width that overwhelmed the intrinsic phonon width. The spectra in PMMA were analyzed with Voigt functions. The dispersion relations obtained in these solids were in good agreement with the literature values of ultrasonic velocity. The spectra in air were well fitted with Lorentzian curve representing the phonon lifetime, and the absorption as well as the phase velocity was obtained.
&lt;title&gt;Intelligent agent support for automated radiology exam&lt;/title&gt; (2000)

A difficult problem in automatic medical image understanding is that for every image type such as x-ray and every body organ such as heart, there exist specific solutions that do not allow for generalization. Just collecting all the specific solutions will not achieve the vision of a computerized physician. To address this problem, we propose an intelligent agent approach that is based on agent-oriented programming is that it combines the benefits of object-oriented programming and expert system. For radiology image understanding, we present a multi- agent system that is composed of two major types of intelligent agents: radiologist agents and patient agents. A patient agent asks for multiple opinions from radiologists agents in interpreting a given set of images and then integrates the opinions. A radiologist agent decomposes the image recognition task into smaller problems that are solved collectively by multiple intelligent sub-agents. Finally, we present a preliminary implementation and running examples of the multi-agent system.
ChemInform Abstract: The Influence of Phosphane Ligands on the Versatility of Ruthenium—Indenylidene Complexes in Metathesis. (2010)

Abstract Five novel Ru‐indenylidene complexes (Ia‐e) are prepared and investigated as pre‐catalysts in ring‐closing metathesis (RCM) of dienes and enynes, ring‐rearrangement metathesis (RRM), cross metathesis (CM) and ring‐opening metathesis polymerization (ROMP, not shown).
Data from The Transcriptional Regulator Sin3A Contributes to the Oncogenic Potential of STAT3 (2023)

&lt;div&gt;Abstract&lt;p&gt;Epigenetic silencing of promoter and enhancer regions is a common phenomenon in malignant cells. The transcription factor STAT3 is aberrantly activated in several tumors, where its constitutive acetylation accounts for the transcriptional repression of a number of tumor suppressor genes (TSG) via molecular mechanisms that remain to be understood. Using nucleophosmin-anaplastic lymphoma kinase–positive (NPM-ALK&lt;sup&gt;+&lt;/sup&gt;) anaplastic large-cell lymphoma (ALCL) as model system, we found in cells and patient-derived tumor xenografts that STAT3 is constitutively acetylated as a result of ALK activity. STAT3 acetylation relied on intact ALK-induced PI3K- and mTORC1-dependent signaling and was sensitive to resveratrol. Resveratrol lowered STAT3 acetylation, rescued TSG expression, and induced ALCL apoptotic cell death. STAT3 constitutively bound the Sin3A transcriptional repressor complex, and both STAT3 and Sin3A bound the promoter region of silenced TSG via a resveratrol-sensitive mechanism. Silencing SIN3A caused reexpression of TSG, induced ALCL apoptotic cell death &lt;i&gt;in vitro&lt;/i&gt;, and hindered ALCL tumorigenic potential &lt;i&gt;in vivo&lt;/i&gt;. A constitutive STAT3–Sin3A interaction was also found in breast adenocarcinoma cells and proved critical for TSG silencing and cell survival. Collectively, these results suggest that oncogene-driven STAT3 acetylation and its constitutive association with Sin3A represent novel and concomitant events contributing to STAT3 oncogenic potential.&lt;/p&gt;Significance:&lt;p&gt;This study delineates the transcriptional regulatory complex Sin3A as a mediator of STAT3 transcriptional repressor activity and identifies the STAT3/Sin3A axis as a druggable target to antagonize STAT3-addicted tumors.&lt;/p&gt;&lt;/div&gt;
Distraction: Friend or Foe (2013)

The classic image in the psychology of driver-car interaction is that of a driver that wants to pay attention to the road: the job of designers is to avoid drawing the driver’s attention away from the road. A number of changes in drivers and cars makes this approach obsolete. Specifically, the following questions are pertinent: • Do drivers want to pay attention to the road? • Can drivers pay attention to the road? • Is attention/distraction the right metric for assessing the effects (positive or negative) of design? • How do new interfaces necessitate a change in our thinking about attention/distraction? • How do fully automated (autonomous) and partially automated vehicles necessitate a change in our thinking about attention/distraction? • How can interface design improve driver attention/performance (as opposed to merely reducing attentional demands)?
Marathon Runner’s Retinopathy (2009)

Strenuous exercise increases activated platelets and other clotting factor elements. During exercise, this increase in clotting factors in the coagulation cascade is usually balanced by activation of key elements in the fibrinolysis cascade as well. However, certain individuals, especially those who already have a predisposition to clotting or other thrombogenic risk factors may disrupt the balance between coagulation and fibrinolysis during strenuous exercise favoring coagulation which places them at risk for thrombus formation.
Mode of Action of Lactoperoxidase as Related to Its Antimicrobial Activity: A Review (2014)

Lactoperoxidase is a member of the family of the mammalian heme peroxidases which have a broad spectrum of activity. Their best known effect is their antimicrobial activity that arouses much interest in in vivo and in vitro applications. In this context, the proper use of lactoperoxidase needs a good understanding of its mode of action, of the factors that favor or limit its activity, and of the features and properties of the active molecules. The first part of this review describes briefly the classification of mammalian peroxidases and their role in the human immune system and in host cell damage. The second part summarizes present knowledge on the mode of action of lactoperoxidase, with special focus on the characteristics to be taken into account for in vitro or in vivo antimicrobial use. The last part looks upon the characteristics of the active molecule produced by lactoperoxidase in the presence of thiocyanate and/or iodide with implication(s) on its antimicrobial activity.
Erythropoiesis and transferrin receptors (2015)

Erythrocytes contain more than 60% of the iron of the body and each day, differentiating erythroid cells uptake around 20 mg of iron for heme synthesis. Accordingly, TfR1 is one of the most abundant membrane proteins of the erythroblasts and it is not surprising that specific regulations regarding both its expression and its mechanism of action operate in erythroblasts. The signaling functions of both TfR1 and TfR2 in erythroid cells were unexpected and these recent findings open a new field of research regarding the last steps of erythroid differentiation and their regulation.
Nonlinear Model Identification of Wind Turbine With a Neural Network (2004)

A nonlinear model of wind turbine based on a neural network (NN) is described for the estimation of wind turbine output power. The proposed nonlinear model uses the wind speed average, the standard deviation and the past output power as input data. An anemometer with a sampling rate of one second provides the wind speed data. The NN identification process uses a 10-min average speed with its standard deviation. The typical local data collected in September 2000 is used for the training, while those of October 2000 are used to validate the model. The optimal NN configuration is found to be 8-5-1 (8 inputs, 5 neurons on the hidden layer, one neuron on the output layer). The estimated mean square errors for the wind turbine output power are less than 1%. A comparison between the NN model and the stochastic model mostly used in the wind power prediction is done. This work is a basic tool to estimate wind turbine energy production from the average wind speed.
Targeting Trained Innate Immunity With Nanobiologics to Treat Cardiovascular Disease (2021)

[Figure: see text].
Secure Comparison Protocol for Promoting Business to Business Collaboration on the Blockchain (2021)

To promote Industry 4.0 and Society 5.0 and so on, it is important to connect and share data so that every member can trust it. Blockchain technology is currently attracting attention as the most advanced tool and has been used in the financial field and so on. In this paper, we focus on the industrial field, using homomorphic encryption and blockchain technique. Each company on the supply chain can exchange confidential information on encrypted data and utilize the data for their own business.
ChemInform Abstract: Synthesis of Carbohydrate Derived α‐Methylene‐γ‐lactones by Diastereoselective, Low Temperature Reformatzky‐Type Reactions. (1987)

Abstract The protected uloses (I), (IV), (VI), or (VIII) react with the bromomethylacrylate (II) and Zn/Ag‐graphite to yield the ester (III) or the spirolactones (V), (VII), and (IX) respectively.
Targeting the gut microbiota in inflammatory bowel diseases: where are we? (2023)

The gut microbiota is now recognized to be a key driver of mucosal inflammation in inflammatory bowel disease (IBD). Robust functional and compositional alterations of the gut microbiota have been described in IBD with a reduction in bacterial diversity, a reduction in some anti-inflammatory anaerobic bacteria, and an increase in bacteria with pro-inflammatory potential. However, despite 15 years of active research, therapeutical applications are still lacking. Recent studies have shed new light on how targeting the gut microbiota can be beneficial in IBD with fecal microbiota transplantation, next-generation probiotics, and phage therapy. Given the similarities in dysfunction and structure of the gut microbiota between IBD and other chronic conditions associated with intestinal inflammation, such as celiac disease, Familial Mediterranean Fever, or common variable immunodeficiency, common therapeutic strategies targeting the host-microbiota symbiosis may be applied in these different conditions.
Simulation Analysis for the Hydraulic Lifting System Reliability of Tower Crane Based on Fault Tree (2013)

The reliability of the hydraulic lifting system of tower crane directly affects safety of the whole machine. Fault tree was built according to the actual structure of the system,the reliability simulation evaluation about the hydraulic lifting system was made based on Monte-Carlo algorithm,reliability curves were obtained,the weak points influencing the reliability were found,the improved ways for this system were concluded. It provides reference for the further optimization and maintenance of the hydraulic lifting system and has certain engineering application value.
Effect of the terminal branching structure of some liquid-crystalline biphenyl carboxylates on the stability of the antiferroelectric phase (1995)

Three different series of smectic liquid-crystalline biphenyl carboxylates have been prepared and their smectic properties investigated. The ‘lateral’ alkyl chain at the branching carbon was varied from methyl to hexyl for the homologous series of 4-(1-alkylheptyloxycarbonyl)phenyl 4′-octyloxybiphenyl-4-carboxylates (series A). A smectic phase which has the same structure as the antiferroelectric phase (SCA*) or ‘anticlinic’ phase (SCA′) was observed for all the members of the series except the pentyl homologue. The smectic layer thicknesses for the homologous series were found to increase as ascending the ‘lateral’ alkyl chain, indicating that the ‘lateral’ alkyl group of the series is in fact directed along the molecular long axis to some extent, which can occur if the molecule has a ‘bent’ structure. A ‘swallow-tailed’ compound, 4-(1-propylbutyloxycarbonyl)phenyl 4′-octyloxybiphenyl-4-carboxylate, and the related ‘ring-tailed’ compounds, 4-(1-cycloalkyloxycarbonyl)phenyl 4′-octyloxybiphenyl-4-carboxylates, were also prepared (series B). The swallow-tailed compound showed an SCA′ phase, whereas the related ring-tailed compounds exhibited an ordinary SCA′ phase, indicating that steric interactions via the terminal alkyl chains stabilize the SCA′ phase. The biphenyl carboxylates possessing a 2-alkyloctyl group at the branching chiral centre, i.e., 4-(2-methylalkyloxycarbonyl)phenyl 4′-octyloxybiphenyl-4-carboxylates (series C), were found to exhibit no SCA* phase.
Polyphosphate: a target for thrombosis attenuation (2014)

In this issue of Blood, Travers et al report that a number of synthetic polyphosphate (polyP) inhibitors are able to reduce thrombosis in mice without increasing bleeding as much as heparin.
Supplementary Table 4 from Obesity Is Associated with Altered Tumor Metabolism in Metastatic Melanoma (2023)

&lt;p&gt;Body mass index values by patient ID for all RNASeq cohorts.&lt;/p&gt;
Associations of Adiponectin Levels With Incident Impaired Glucose Metabolism and Type 2 Diabetes in Older Men and Women (2006)

A high adiponectin level was strongly associated with a lower risk of IGM and type 2 diabetes, particularly in women. These results suggest that adiponectin is involved in the pathophysiology linking obesity to type 2 diabetes.
Field of Junctions. (2020)

We introduce a bottom-up model for jointly finding many boundary elements in an image, including edges, curves, corners and junctions. The model explains boundary shape in each small patch using a junction with M angles and a freely-moving vertex. Images are analyzed by solving a non-convex optimization problem using purposefully-designed algorithms, cooperatively finding M+2 junction values at every pixel. The resulting field of junctions is simultaneously an edge detector, a corner/junction detector, and a boundary-aware smoothing of regional appearance. We demonstrate how it behaves at different scales, and for both single-channel and multi-channel input. Notably, we find it has unprecedented resilience to noise: It succeeds at high noise levels where previous methods for segmentation and for edge, corner and junction detection fail.
[Analgosedation (managed anesthesia care--MAC) with propofol and piritramide for controlled cyclophotocoagulation of the eye]. (2000)

The new method of controlled cyclophotocoagulation of the eye is an example of a short, non-invasive procedure that is still too painful to be done under local anaesthesia alone. The risks associated with general anaesthesia, on the other hand, seem to be inappropriately high compared to the risks associated with the procedure itself. Therefore, for this procedure, we combined local anaesthesia with 0.5% proxymetacain and 10% cocaine and sedation with propofol and analgesia with piritramide. Our experiences with this method have been positive. We have applied our method to 42 patients undergoing a total of 53 procedures and we have seen no major changes in haemodynamics and only two cases of momentary slight ventilatory depression. Therefore, we conclude that our method of managed anaesthesia care is suitable for patients undergoing cyclophotocoagulation of the eye, combining patient comfort with haemodynamic stability and minimal risk for the patient.
Gender-Based Differences in Drug Prescription: Relation to Adverse Drug Reactions (2009)

Antibacterials and anti-inflammatory agents cause more ADRs in females as compared to males.
A Multi-Functional Electrolyte for Lithium-Ion Batteries (2016)

The high thermal conduction resistances of lithium-ion batteries (LIBs) severely limit the effectiveness of conventional external thermal management systems (TMSs). One potential solution is to remove heat locally inside the cell by evaporating a volatile component of a multi-functional electrolyte (MFE). Low boiling point hydrofluoroethers (HFE) were first used by Arai to increase LIB electrolyte flash points, and have been proven to be compatible with LIB chemistry. HFE-7000 and ethyl methyl carbonate (EMC) 1:1 by volume are used to solvate 1.0 M LiTFSI to produce a MFE for the proposed cooling system. In part I, the non-boiling electrochemical performance of the MFE was compared to a carbonate-only electrolyte. The results showed that despite its high volatility, HFE-7000 is a feasible co-solvent for LIBs. In the present study, copper antimonide (Cu2Sb) and lithium iron phosphate (LiFePO4) are used in a full cell architecture with the MFE in a custom electrolyte boiling facility. The facility enables direct viewing of the vapor generation within the full cell and characterizes the galvanostatic electrochemical performance. Test results show that the LFP/Cu2Sb cell is capable of operation even when a portion of the more volatile HFE-7000 is continuously evaporated under an extreme heat flux.