gebhart/patrepeval huggingface dataset:
Analysis of Risk Factors for Catheter-Related Bacteremia in 2000 Permanent Dual Catheters for Hemodialysis (2009)

Reducing CRB is still a challenge for nephrologists to reduce patient morbidity and mortality. Our study could demonstrate that diabetes, previous history of CRB, site of catheter implantation and duration of catheter use were the most important risk factors for bacteremia. Therefore, to prevent CRB, particular attention should be paid to patients with diabetes and a previous history of bacteremia following strict hygienic and aseptic rules for catheter handling associated with the regular use of antiseptic lock solutions.
Platform For Analyzing Multi-Tasking Capabilities During Bci Operation (2020)

Operating brain-actuated devices requires split attention between the interaction of the device with its environment and the Brain-Computer Interface (BCI) feedback. Recently we demonstrated that BCI feedback could be provided via tactile stimulation and no difference between tactile and visual BCI feedback could be found. In this work we want to present a platform for analyzing these multi-tasking capabilities during BCI operation. Thereby, the subjects will have to perform a visual engaging and complex task in a game like setup while interacting with the BCI in a coordinated multi-tasking manner.
Multilectin Assay for Detecting Fibrosis-Specific Glyco-Alteration by Means of Lectin Microarray (2010)

The multiple lectin-antibody sandwich immunoassay targeting AGP enables monitoring of disease progression in chronic hepatitis patients at risk of developing hepatocellular carcinoma.
Sign Language Recognition Using Boosted Volumetric Features (2007)

This paper proposes a method for sign language recognition that bypasses the need for tracking by classifying the motion directly. The method uses the natural extension of haar like features into the temporal domain, computed efficiently using an integral volume. These volumetric features are assembled into spatio-temporal classifiers using boosting. Results are presented for a fast feature extraction method and 2 different types of boosting. These configurations have been tested on a data set consisting of both seen and unseen signers performing 5 signs producing competitive results. 1
Altering the Cellular Location of an Antigen Expressed by a DNA-Based Vaccine Modulates the Immune Response (1999)

The potential for DNA vaccines encoding mutated versions of the same antigen to modulate immune responses in C3H/HeN mice was investigated. We created expression plasmids that encoded several versions of glycoprotein D (gD) from bovine herpesvirus 1, including authentic membrane-anchored glycoprotein (pSLRSV.AgD), a secreted glycoprotein (pSLRSV.SgD), and an intracellular protein (pSLRSV.CgD). Immunization of an inbred strain of mice with these plasmids resulted in highly efficacious and long-lasting humoral and cell-mediated immunity. We also demonstrated that the cell compartment in which plasmid-encoded gD was expressed caused a deviation in the serum immunoglobulin (Ig) isotype profile as well as the predominant cytokines secreted from the draining lymph node. Immunization of C3H/HeN mice with DNA vaccines encoding cell-associated forms of gD resulted in a predominance of serum IgG2a and gamma interferon-secreting cells within the spleens and draining lymph nodes. In contrast, mice immunized with a secreted form of this same antigen displayed immune responses characterized by greater levels of interleukin 4 in the draining lymph node and IgG1 as the predominant serum isotype. We also showed evidence of compartmentalization of distinct immune responses within different lymphoid organs.
Comparison of the Immunotoxicity of Propanil and Its Metabolite, 3,4-Dichloroaniline, in C57BI/6 Mice (1992)

Propanil (3,4-dichioropropionaniine), used extensively as a postemergence herbicide in rice and wheat, has as its major metabolite, 3,4-dichloroaniline (DCA). Propanil has previously been shown to affect the T cell-dependent antibody response. To determine the immunotoxicity of DCA, as well as extend the previous immunotoxicity studies, several T cell-dependent and -independent immune responses were determined after DCA or propanil exposure. Unlike propanil, DCA caused a significant reduction in T-dependent antibody production (anti-SRBC response) only at a high dose (150 mg/kg). DCA or propanil at 150 or 200 mg/kg, respectively, caused a significant reduction in the number of anti-DNP antibody producing cells. However, doses of 37 or 50 mg/kg of DCA or propanil, respectively, caused an increase in the number of anti-DNP antibody producing cells. These data indicate that both propanil and DCA have a differential effect on the T-independent antibody response depending on the dose. Similar to propanil, DCA (at 150 mg/kg) caused a significant increase in spleen weight and cellularity. The effect of DCA or propanil on selected cellular immune functions was also determined. DCA caused a significant decrease in the natural killer (NK) cell activity at doses of 75 or 150 mg/kg. and propanil caused a significant decrease at 100 or 200 mg/kg. Cytotoxic T lymphocyte activity, however, was unaffected even at 150 or 200 mg/kg DCA or propanil, respectively. Thus, it appears that T cells are relatively resistant to the effects of propanil and DCA, whereas, other immune cell types, e.g., NK cells are sensitive to its effects.
Symblicit Calculation of Long-Run Averages for Concurrent Probabilistic Systems (2010)

Model checkers for concurrent probabilistic systems have become very popular within the last decade. The study of long-run average behavior has however received only scant attention in this area, at least from the implementation perspective. This paper studies the problem of how to efficiently realize an algorithm for computing optimal long-run average reward values for concurrent probabilistic systems. At its core is a variation of Howard and Veinott's algorithm for Markov decision processes, where symbolic and non-symbolic representations are intertwined in an effective manner: the state space is represented using binary decision diagrams, while the linear equation systems which have to be solved for the induced Markov chains to improve the current scheduler are solved using an explicit state representation. In order to keep the latter small, we apply a symbolic bisimulation minimization algorithm to the induced Markov chain. The scheduler improvement step itself is again performed on symbolic data structures. Practical evidence shows that the implementation is effective, and sometimes uses considerably less memory than a fully explicit implementation.
Hydronium ion diffusion in model proton exchange membranes at low hydration: insights from <i>ab initio</i> molecular dynamics (2021)

Sequence of steps in the reaction of hydronium (H<sub>3</sub>O<sup>+</sup>) with sulfonate (SO<sub>3</sub><sup>−</sup>) contributing to the proton structural diffusion mechanism in a low-hydration environment of a proton-exchange-membrane (PEM) mimic.
Cellulose microfibril crystallinity is reduced by mutating C-terminal transmembrane region residues CESA1 <sup>A903V</sup> and CESA3 <sup>T942I</sup> of cellulose synthase (2012)

The mechanisms underlying the biosynthesis of cellulose in plants are complex and still poorly understood. A central question concerns the mechanism of microfibril structure and how this is linked to the catalytic polymerization action of cellulose synthase (CESA). Furthermore, it remains unclear whether modification of cellulose microfibril structure can be achieved genetically, which could be transformative in a bio-based economy. To explore these processes in planta, we developed a chemical genetic toolbox of pharmacological inhibitors and corresponding resistance-conferring point mutations in the C-terminal transmembrane domain region of CESA1(A903V) and CESA3(T942I) in Arabidopsis thaliana. Using (13)C solid-state nuclear magnetic resonance spectroscopy and X-ray diffraction, we show that the cellulose microfibrils displayed reduced width and an additional cellulose C4 peak indicative of a degree of crystallinity that is intermediate between the surface and interior glucans of wild type, suggesting a difference in glucan chain association during microfibril formation. Consistent with measurements of lower microfibril crystallinity, cellulose extracts from mutated CESA1(A903V) and CESA3(T942I) displayed greater saccharification efficiency than wild type. Using live-cell imaging to track fluorescently labeled CESA, we found that these mutants show increased CESA velocities in the plasma membrane, an indication of increased polymerization rate. Collectively, these data suggest that CESA1(A903V) and CESA3(T942I) have modified microfibril structure in terms of crystallinity and suggest that in plants, as in bacteria, crystallization biophysically limits polymerization.
Theory and Use of Conditional Composition (1994)

&r sd sp br sh Iq 3i tl Ii @ s
A New Antimicrobial Agent: Poly (3‐hydroxybutyric acid) Oligomer (2019)

In this work, it is first reported that the poly (3-hydroxybutyric acid) (PHB) oligomer with a few degrees of polymerization possesses effective antibacterial and antifungal properties. Two preparation methods for the PHB oligomer are described, namely, one-step ring-opening polymerization of β-butyrolactone and extraction from the fermented PHB polymer. An appropriate amount of the synthesized PHB oligomer shows no physiological toxicity to the skin and major organs of mice. Topological application of the synthesized PHB oligomer imparts antimicrobial ability to non-antibacterial fabrics with washing resistance. The synthesized PHB oligomer offers effective sterilization and promotes wound healing in infected nude mice. Most importantly, the PHB oligomer is also reactive to drug-resistant bacteria. These results suggest that the PHB oligomer is not only a great candidate for antimicrobial modification but also a promising one for biomedical applications. Finally, the antimicrobial mechanisms of the PHB oligomer are revealed, and these include disruption of biofilm and the bacterial wall/membrane, leakage of the intracellular content, inhibition of protein activity, and change in the transmembrane potential.
Safe High Stiffness Impedance Control for Series Elastic Actuators using Collocated Position Feedback (2022)

Physical human-robot interaction applications re-quiring safety and compliance characteristics usually employ mechanical devices as series elastic actuators (SEAs). Impedance control schemes for SEAs have been investigated to overcome the limited displayable stiffness at the end-point, represented by the stiffness of the physical spring, in a passive way. SEAs usually mount two encoders on both motor and load sides for position measurements. However, in many applications, the installation of a load-side encoder is not trivial, both for cost and manufacturing issues. In this scenario, a Kalman Filter (KF) based on MEMS accelerometers has been proposed for external force and load side quantities estimation. A novel impedance control scheme exploiting this approach is proposed, to effectively overcome the stiffness of the physical spring while maintaining passivity at the end-point. Compared to conventional load side encoder-based impedance control schemes, the proposed one presents comparable performances, as shown by simulation and experimental results.
The Role of AI in Driving the Sustainability of the Chemical Industry (2023)

Sustainability is here to stay. As businesses migrate away from fossil fuels and toward renewable sources, chemistry will play a crucial role in bringing the economy to a point of net-zero emissions. In fact, chemistry has always been at the forefront of developing new or enhanced materials to fulfill societal demands, resulting in goods with appropriate physical or chemical qualities. Today, the main focus is on developing goods and materials that have a less negative impact on the environment, which may include (but is not limited to) leaving behind smaller carbon footprints. Integrating data and AI can speed up the discovery of new eco-friendly materials, predict environmental impact factors for early assessment of new technological integration, enhance plant design and management, and optimize processes to reduce costs and improve efficiency, all of which contribute to a more rapid transition to a sustainable system. In this perspective, we hint at how AI technologies have been employed so far first, at estimating sustainability metrics and second, at designing more sustainable chemical processes.
Isolation and partial purification of a red tide (Gymnodinium breve) cytolytic factor(s) from cultures of Gomphosphaeria aponina (1979)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTIsolation and partial purification of a red tide (Gymnodinium breve) cytolytic factor(s) from cultures of Gomphosphaeria aponinaLeslie F. McCoy Jr., David L. Eng-Wilmot, and Dean F. MartinCite this: J. Agric. Food Chem. 1979, 27, 1, 69–74Publication Date (Print):January 1, 1979Publication History Published online1 May 2002Published inissue 1 January 1979https://pubs.acs.org/doi/10.1021/jf60221a013https://doi.org/10.1021/jf60221a013research-articleACS PublicationsRequest reuse permissionsArticle Views36Altmetric-Citations8LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Synthesis of Coinage Metal Cation Adducts of Nb(C5H4SiMe3)2H(CO). X-ray Crystal Structure of [{Nb(C5H4SiMe3)2(CO)}2(.mu.-H)2Cu]PF6 (1995)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSynthesis of Coinage Metal Cation Adducts of Nb(C5H4SiMe3)2H(CO). X-ray Crystal Structure of [{Nb(C5H4SiMe3)2(CO)}2(.mu.-H)2Cu]PF6Antonio Antinolo, Fernando Carrillo, Bruno Chaudret, Mariano Fajardo, Santiago Garcia-Yuste, Fernando J. Lahoz, Maurizio Lanfranchi, Jose A. Lopez, Antonio Otero, and Maria Angela PellinghelliCite this: Organometallics 1995, 14, 3, 1297–1301Publication Date (Print):March 1, 1995Publication History Published online1 May 2002Published inissue 1 March 1995https://pubs.acs.org/doi/10.1021/om00003a033https://doi.org/10.1021/om00003a033research-articleACS PublicationsRequest reuse permissionsArticle Views81Altmetric-Citations15LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (2)»Supporting Information Supporting Information Get e-Alerts
Preface (2021)

This February 2022 issue of the <italic xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">IEEE Transactions on Visualization and Computer Graphics (TVCG)</i> contains the proceedings of IEEE VIS 2021, held online on October 24-29, 2021, with General Chairs from Tulane University and Universidade de Sao Paulo. With IEEE VIS 2021, the conference series is in its 32nd year.
A comparative study of the antimycotic activity of a miconazole HP-beta cyclodextrin solution and a surfactant solution. (1999)

The antimycotic activity of a new parenteral solution containing miconazole was compared to that of a marketed solution (Daktarin IV solution). This solution has been withdrawn from the belgian market probably because of the toxic effects related to the presence of polyoxyl 35 castor oil. We propose a new formulation containing 10 mg of miconazole per ml (as the marketed solution), in combination with HP-beta cyclodextrin and lactic acid. The MIC of these two solutions were determined by broth microdilution method (following the NCCLS guidelines) against 15 yeasts and 16 filamentous fungi isolates. This study showed that MIC obtained with these two solutions are not significantly different. In vitro, the cyclodextrin solution has the same antimycotic activity as the Daktarin IV solution and can be proposed as a safe and effective parenteral solution to replace the previous surfactant solution.
Assessment of Periodic Open Cellular Structures for Enhanced Heat Conduction in Catalytic Fixed‐Bed Reactors (2015)

In this paper, the effective heat conductivity of periodic open cellular structures (POCS) is investigated by means of a systematic numerical study. 3D geometries of different configurations were considered, representing the unit cell volume of the modular POCS. Special emphasis is put on the strut morphology, i.e. the strut cross sectional shape and the distribution of the solid material along the strut. At the same porosity, the optimal designed structures show a higher effective heat conductivity than conventional open‐cell solid foams with random cell geometry. This possibility to exceed the effective thermal conductivity of state‐of‐the‐art open‐cell foams by optimization of their geometrical properties is an interesting novel aspect of high relevance regarding their application in catalytic reactors.
Synthesis and photopolymerization of phosphonic acid monomers for applications in compomer materials (2010)

Abstract Novel methacrylate monomers bearing phosphonic acid groups 1 and 2 as well as new sulfur methacrylates 9 and 10 have been prepared in good yields from thiophenol. They have been fully characterized by 1 H‐NMR, 13 C‐NMR, 31 P‐NMR, and HRMS. Their copolymerization with a bis‐GMA : TEGDMA (1 : 1) blend has been investigated with photodifferential scanning calorimetry at 50°C with camphorquinone as a photoinitiator and ethyl 4‐(dimethylamino)benzoate (EDAB) as a coinitiator. The higher the content of acidic monomer 1 or 2 incorporated in the bis‐GMA : TEGDMA (1 : 1) blend, the lower the mixtures reactivity. The phosphonic acid group has been proved to be responsible for this drop of reactivity. © 2010 Wiley Periodicals, Inc. J Appl Polym Sci, 2010
Association of cord blood vitamin D at delivery with postpartum depression in Australian women (2015)

This largest study to date of 25(OH)D levels at delivery and PPD did not reveal a consistent link with PPD.
Metabolic studies on mycobacteria--II. Glyoxylate by-pass (TCA cycle) enzymes of slow and fast growing mycobacteria. (1986)

Glyoxylate by-pass of tricarboxylic acid cycle (TCA) comes into prominence during survival of microorganisms under oxygen limitations and study of these enzymes may contribute to understanding of physiology of 'persisters' in various mycobacterial diseases. The enzymes of glyoxylate by-pass have been assayed in the extracts of various mycobacterial species, namely, M. tuberculosis H37Rv, M. tuberculosis H37Ra, M. flavescens, M. vaccae, M. smegmatis and Mycobacteria strain w (M.w.). M.w. has been included because of its close antigenic resemblance to M. leprae. It has been found that all of the above investigated species possess isocitrate lyase and malate synthetase, the key enzymes of glyoxylate by-pass. The presence of the enzymes is being reported for the first time in M. flavescens, M. vaccae and M.w. whereas these were earlier shown to be present in M. tuberculosis and M. smegmatis. It was also demonstrated in M.w. where acetate alone could not serve as sole source of carbon, but in the presence of glycerol stimulates the activity of glyoxylate pathway enzymes. The importance of these findings has been discussed.
Personalized tag recommendation based on generalized rules (2013)

Tag recommendation is focused on recommending useful tags to a user who is annotating a Web resource. A relevant research issue is the recommendation of additional tags to partially annotated resources, which may be based on either personalized or collective knowledge. However, since the annotation process is usually not driven by any controlled vocabulary, the collections of user-specific and collective annotations are often very sparse. Indeed, the discovery of the most significant associations among tags becomes a challenging task. This article presents a novel personalized tag recommendation system that discovers and exploits generalized association rules, that is, tag correlations holding at different abstraction levels, to identify additional pertinent tags to suggest. The use of generalized rules relevantly improves the effectiveness of traditional rule-based systems in coping with sparse tag collections, because: (i) correlations hidden at the level of individual tags may be anyhow figured out at higher abstraction levels and (ii) low-level tag associations discovered from collective data may be exploited to specialize high-level associations discovered in the user-specific context. The effectiveness of the proposed system has been validated against other personalized approaches on real-life and benchmark collections retrieved from the popular photo-sharing system Flickr.
Solving GPS Time and Position without Navigation Data (2002)

This paper presents a novel method for computing a GPS receiver&amp;apos;s po-sition from C/A-code measurements, valid satellite ephemerides and pseudo-range correction parameters. Precise system time is not required. Thus, the navigation message need not be demodulated from the signal if the current ephemerides and pseudo-range correction parameters are otherwise available, for example through a cellular network. The proposed method requires initial approximations for position and time, and it is shown that an error of about 150 kilometers or three min-utes is allowed in these approximations. Simulation results are presented that indicate that the accuracy of this method approaches that of the conventional pseudo-range solution. Moreover, this procedure requires only marginally more computations than the conventional iterative least squares solution. 1