gebhart/patrepeval huggingface dataset:
Efficient implementation of rotation operations for high performance QRD-RLS filtering (2002)

In this paper we present practical techniques for implementing Givens rotations based on the well-known CORDIC algorithm. Rotations are the basic operation in many high performance adaptive filtering schemes as well as numerous other advanced signal processing algorithms relying on matrix decompositions. To improve the efficiency of these methods, we propose to use "approximate rotations", whereby only a few (i.e. r/spl Lt/b, where b is the operand word length) elementary angles of the original CORDIC sequence are applied, so as to reduce the total number of required shift add operations. This seamingly rather ad hoc and heuristic procedure constitutes a representative example of a very useful design concept termed "approximate signal processing" recently introduced and formally exposed by S.H. Nawab et al. (1997), concerning the trade-off between system performance and implementation complexity, i.e. between accuracy and resources. This is a subject of increasing importance with respect to the efficient realization of demanding signal processing tasks. We present the application of the described rotation schemes to QRD-RLS filtering in wireless communications, specifically high speed channel equalization and beamforming, i.e. for intersymbol and co-channel/interuser interference suppression, respectively. It is shown via computer simulations that the convergence behavior of the scheme using approximate Givens rotations is insensitive to the value of r, and that the misadjustment error decreases as r is increased, opening zip possibilities for "incremental refinement" strategies.
A class of artificial materials isorefractive with free space (2003)

A new class of dispersion-free artificial material that is isorefractive with free space is presented. Materials can be fabricated by composing an array of conducting inclusions in a tenuous host medium that are symmetric with respect to the direction of propagation. Strategies are proposed for both longitudinal and radial propagation. In the presence of the transverse electromagnetic mode, the inclusions are transversely polarized and hence raise the effective relative dielectric constant of the material. The inclusions simultaneously constrict the magnetic field lines, lowering the effective permeability by the same factor. The net effect is to make an artificial material with the same speed of propagation as the host material, but with a lower effective impedance. Such a material can be used to improve aperture efficiency in impulse radiating antennas. Limitations of the materials including field enhancement due to the inclusions and skin losses due to finite conductivities are also discussed.
Specific iron chelators determine the route of ferritin degradation (2009)

Deferoxamine (DFO) is a high-affinity Fe (III) chelator produced by Streptomyces pilosus. DFO is used clinically to remove iron from patients with iron overload disorders. Orally administered DFO cannot be absorbed, and therefore it must be injected. Here we show that DFO induces ferritin degradation in lysosomes through induction of autophagy. DFO-treated cells show cytosolic accumulation of LC3B, a critical protein involved in autophagosomal-lysosomal degradation. Treatment of cells with the oral iron chelators deferriprone and desferasirox did not show accumulation of LC3B, and degradation of ferritin occurred through the proteasome. Incubation of DFO-treated cells with 3-methyladenine, an autophagy inhibitor, resulted in degradation of ferritin by the proteasome. These results indicate that ferritin degradation occurs by 2 routes: a DFO-induced entry of ferritin into lysosomes and a cytosolic route in which iron is extracted from ferritin before degradation by the proteasome.
Coordination control policy for mobile sensor networks with shared heterogeneous resources (2005)

This paper considers centralized coordination of cooperating heterogeneous wireless sensors with multiple shared resources. A discrete event controller (DEC) is used to sequence the most suitable tasks for stationary and mobile sensors according to the current perception of the environment, efficiently handling simultaneous missions of different priority. Its matrix formulation, apart from making the assignment of the mission planning straightforward and easily adaptable if agents or applications change, provides a powerful tool to analyze deadlock situations and implement efficient deadlock avoidance policies. It also represents a complete dynamical description of the system which allows computer simulation analysis. The matrix formulation also allows fast implementation of DEC for actual WSNs.
Postnatal Decrease in Insulin Binding to Erythrocytes in Infants of Diabetic Mothers* (1988)

To clarify the role of insulin receptors in the macrosomia and the tendency to hypoglycemia in infants of mothers with insulin-treated diabetes mellitus (IDM) we studied insulin binding in erythrocytes from mixed umbilical blood and from peripheral venous blood collected when the infants were 3-14 days old. Normal infants were matched for gestational and postnatal age. The IDM infants were macrosomic, with significantly higher birth weights relative to gestational age than the control infants. Plasma free insulin concentrations in cord blood were 15-fold higher in the IDM than in the normal infants and more than 3-fold higher in the peripheral venous blood at the median age of 4 days. Hypoglycemia occurred in 12 of the 17 IDM and in none of the normal infants. In umbilical blood insulin binding to erythrocytes was similar in the IDM and normal infants. In both groups insulin binding decreased during the first postnatal weeks, but the decrease was significantly greater in the IDM than in the normal infants. The decrease in insulin binding to erythrocytes was a consequence of decreased receptor affinity as well as decreased receptor concentration in the IDM infants, but was mainly due to decreased receptor concentration in the normal infants. We conclude that insulin binding to its erythrocyte receptor in cord blood in IDM infants is similar to that in normal infants in spite of the simultaneous gross hyperinsulinemia in the IDM infants. The resulting increase in insulin action would then contribute to the tendency toward hypoglycemia and may be partly responsible for the macrosomia in IDM infants. The marked postnatal decrease in insulin binding in IDM infants is a possible explanation for their diminishing risk of hypoglycemia after the first few days of life in spite of persisting hyperinsulinemia.
Sensitivity Enhancement of Exciton Coupling by Fluorescence Detected Circular Dichroism (FDCD) (1997)

ADVERTISEMENT RETURN TO ISSUEPREVCommunicationNEXTSensitivity Enhancement of Exciton Coupling by Fluorescence Detected Circular Dichroism (FDCD)Jian-Guo Dong, Akio Wada, Takashi Takakuwa, Koji Nakanishi, and Nina BerovaView Author Information Department of Chemistry, Columbia University New York, New York 10027 JASCO Corporation, 2967-5, Ishikawa-Cho Hachioji-Shi, Tokyo 192, Japan Cite this: J. Am. Chem. Soc. 1997, 119, 49, 12024–12025Publication Date (Web):December 10, 1997Publication History Received27 June 1997Published online10 December 1997Published inissue 1 December 1997https://doi.org/10.1021/ja9721172Copyright © 1997 American Chemical SocietyRequest reuse permissionsArticle Views530Altmetric-Citations22LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit Read OnlinePDF (120 KB) Get e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information SUBJECTS:Chromophores,Excitons,Fluorescence,Fluorescence detection,Molecules Get e-Alerts
Long‐term Lens Organ Culture System with a Method for Monitoring Lens Optical Quality<sup>¶</sup> (2005)

ABSTRACT The Scan Tox™ System is a method for monitoring lens optical quality (focus or lack of focus) in culture conditions, which mimic conditions inside the eye. The ocular lens is an ideal organ for long‐term culture experiments because it has no direct blood supply and no connection to the nervous system. The Scan Tox™ System makes it possible to keep lenses for long‐term studies of up to a few weeks. The use of cultured lenses, mainly bovine, replaces the need for testing the effects of potentially damaging agents on live animals. This optical monitoring apparatus uses a computer‐operated scanning laser beam, a video‐camera system and a video frame analyzer to record the focal length and transmittance of the cultured lens. The scanner is designed to measure the focal length at points across the diameter of the lens. The lens container permits the lens to be exposed to a vertical laser beam from below. The laser source projects its light onto a plain mirror, which is mounted at 45° on a carriage assembly. The mirror reflects the laser beam directly up through the test lens. The mirror carriage is connected to a positioning motor, which moves the laser beam across the lens. The camera sees the cross section of the beams and, by examining the image at each position of the mirror, Scan Tox™ software is able to measure the quality of the lens by calculating the back vertex distance for each beam position. The cultured lenses continue to maintain their original refractive function. When foreign substances are introduced to a cultured lens, the Scan Tox™ System measures the resulting optical response. This provides a very sensitive means to follow early damage to the eye lens. Because the lens is maintained in an intact state in solutions that are similar to those inside the eye, the lens retains its normal recuperative powers. So in addition to measuring early damage, this system allows measurement of recovery from damage.
Open surgical repair with renal autotransplantation in the treatment of pararenal abdominal aortic aneurysm: a single center experience (2016)

Objective
To report the application of open surgery combined with renal autotransplantation in the treatment of pararenal abdominal aortic aneurysm (AAA) , and to explore its applicability, safety, and efficacy.


Methods
Three cases of pararenal AAA treated by aneurysm resection and artificial blood vessel replacement combined with renal autotransplantation between Jan 2011 and Jan 2016 in our center were retrospectively reviewed.


Results
Procedure success was achieved in all these 3 cases, and there was no in-hospital operation-related complication. During follow-up of 6 months to 5 years, the artificial blood vessels remain patent, the renal function of the autotransplanted kidney is normal, and the clinical outcomes are satisfactory.


Conclusions
For pararenal AAA with complex anatomy, which is difficult for endovascular repair, open surgery combined with renal autotransplantation is feasible, safe, and effective, with good short-to mid-term outcomes.


Key words: 
Open surgery; Renal autotransplantation; Abdominal aortic aneurysm
Fuzzy modeling of metabolic maps in MetNetDB (2004)

Metabolic networks combine metabolism and regulation. These complex networks are difficult to understand and visualize due to the diverse types of information that need to be represented. FCModeler, a publicly available software package is designed to enable the biologist to visualize and model metabolic and regulatory network maps in plants. It links to an interactions database (MetNetDB) containing information on regulatory and metabolic interactions derived from a combination of web databases and input from biologists in their area of expertise. FCModeler evaluates hypotheses and provides a graph-theoretic modeling framework for assessing the large amounts of data captured by high-throughput gene expression experiments. This leads to a new method for classifying gene expression data by combining network, gene ontology, and measured expression information in a fuzzy clustering framework.
Characterisation of a Hepatitis C Virus Subtype 2a Cluster in Scottish PWID with a Suboptimal Response to Glecaprevir/Pibrentasvir Treatment (2022)

This study describes a cluster of HCV genotype 2a infection associated with a lower-than-expected SVR rate following GP treatment in association with the NS5A mutations L31M+R353K.
Proceedings of the 2nd Workshop on High Performance Computational Finance (2009)

Computational finance is an important multi-disciplinary research field. The traditional approaches are falling short, as the volume of data and complexity of the models increase at an astonishing rate. Financial companies increasingly rely on high performance computers to analyze high volumes of financial data, automatically execute trades, and manage risk. As financial market data continues to grow in volume and complexity, and algorithmic trading becomes increasingly popular, there is increased demand for computational power. This is transforming the way that financial markets do business and it offers potential major innovations. Yet, the field is still in its infancy. Only in recent years have we started to see growth in relevant research and in the number of workshops in the area of high performance computational finance.

When we organized the First Workshop on High Performance Computational Finance in 2008, we had envisioned bringing together practitioners, researchers, vendors, and scholars from the complementary fields of computational finance and high performance computing. Our goal was to promote an exchange of ideas and research, discuss future research collaborations and develop new research directions. The success of that first workshop motivated us to organize this second edition. Recent events in the world economy have demonstrated a great need for better models and tools to perform risk analysis and risk management. Therefore, we selected risk management as a focus area for the 2009 workshop.

We have assembled a diverse program, consisting of three keynotes, one invited talk and five presentations selected from the set of submitted papers. Our speakers come from the financial industry, from computer vendors and from academia. Topics range from management of value at risk to frameworks for market data processing to exploitation of new computer architectures. We are confident that this workshop will help stimulate the research in the area of high performance computational finance.
Formation à la conduite (2016)

Le sur-risque accidentel de certains groupes de conducteurs, plus particulièrement celui des jeunes conducteurs novices, est systématiquement observé dans tous les pays peu importe les programmes de formation et d'accès au permis de conduire mis en place. Le colloque 'Formation à la conduite - une vision à 360' des 28ème Entretiens du Centre Jacques Cartier a réuni les 25 et 26 novembre 2015 à Bruxelles, des représentants d'administrations publiques, d'organisations internationales, des chercheurs, des experts et des formateurs pour échanger et débattre sur les innovations et les bonnes pratiques à adopter pour que les programmes d'éducation à la conduite aient un impact significatif sur le bilan routier.
Light-shift suppression in a miniaturized Mx optically pumped Cs magnetometer array with enhanced resonance signal using off-resonant laser pumping (2012)

The performance of an optically pumped Mx magnetometer with miniaturized Cs cell at earth's magnetic field strength (50 μT) is investigated. Operation using detuned high intensity laser light is shown to be superior to the conventional resonant operation in terms of the projected shot-noise-limited ( 50 fT/√Hz) and the actual noise-limited sensitivity using a noise compensation method. The Zeeman light shift effect, emerging due to the off-resonant circularly polarized laser radiation and leading to a strong orientational dependence of the measurement, is suppressed by averaging two identical magnetometer configurations pumped with oppositely circularly polarized light. A residual heading error within the range of 14 nT, limited by the present experimental characterization setup, was achieved.
Enriching SDL Specifications with MSCs. (2000)

Software systems evolve through addition of new behaviors and new components to the existing behavior and architecture. In this paper, we address the issue of enriching automatically SDL specifications with new behaviors specified with MSCs. The new behaviors should not inhibit (invalidate) existing and already validated behavior. In other words, the existing behavior should be preserved in the new SDL specification. We define formally the notion of behavior preservation in the context of SDL, taking into account its semantics, and we illustrate our SDL specification enrichment approach through an example.
Effects of Chronic Intrathecal Infusion of a partial Opioid Agonist in Dogs (2003)

To define the effects of chronic spinal exposure to a highly selective partial differential opioid agonist c[DPen(2),DPen(5)]enkephalin (DPDPE), adult beagles were prepared with chronic lumbar intrathecal catheters. Groups of dogs received intrathecal infusions (100 micro l/h) of saline (vehicle), DPDPE 3 mg/ml or 6 mg/ml for 28 days. Over the 28-day period, saline or 3 mg/ml showed minimal changes in neurological function, whereas in the 6 mg/ml animals, prominent hind limb dysfunction evolved over the 28-day interval. Histopathology in control animals displayed a modest pericatheter reaction considered normal for this model. Dogs receiving DPDPE (three of four at 6 mg/ml and one of four at 3 mg/ml) but not saline (zero of four) developed large inflammatory masses (granulomas) in the intrathecal space located proximal to the catheter tip. In these masses, severe chronic inflammatory changes in combination with necrosis and fibrosis was detected. Occasional focal destruction of neuropil was detected also in the adjacent spinal cord parenchyma. These masses contained extensive accumulation of mouse antihuman macrophages (MAC)-positive inflammatory cells expressing tumor necrosis factor-alpha (TNF-alpha), revealing infiltration of macrophages, granulocytes, and monocytes. In separate animals, prepared with dual intrathecal catheters, lumbar CSF was sampled at specified time points following intrathecal bolus (3 mg/ml) and 24 h DPDPE infusion (3 mg/ml and 6 mg/ml). Steady-state cerebrospinal fluid (CSF) DPDPE levels were 18.6 +/- 1.0 and 22.6 +/- 4.0 micro g/ml for 3 mg/ml and 6 mg/ml infusions respectively. These results indicate that this partial differential opioid agonist DPDPE produces a concentration and time-dependent formation of an intrathecal inflammatory mass.
Mixed Radical/Iodine Charge-Transfer Salts of Dithiadiazolyl Diradicals. Structural Characterization of the Pyridine-Bridged 2:1 Salt 2,6-[(S<sub>2</sub>N<sub>2</sub>C)C<sub>5</sub>H<sub>3</sub>N(CN<sub>2</sub>S<sub>2</sub>)]<sub>2</sub>[I] (1996)

Cosublimation of 2,5-furanbis(1,2,3,5-dithiadiazolyl) [F-2,5-S] and iodine affords 1:1 and 2:1 charge-transfer salts, [F-2,5-S][I] and [F-2,5-S]2[I]. Cosublimation of 2,6-pyridinebis(1,2,3,5-dithiadiazolyl) [P-2,6-S] and iodine affords uniquely the 2:1 charge-transfer salt [P-2,6-S]2[I]. Crystals of the latter belong to the space group P21/c, a = 3.434(3), b = 9.8914(9), c = 30.803(4) Å, β = 91.52(3)°, V = 1045.9(9) Å3, Z = 2. The structure consists of [P-2,6-S] molecules stacked along the x direction. Pairs of stacks are linked head-on through iodine atoms, which themselves form disordered stacks running parallel to x. The internal structural parameters of the two CN2S2 rings within each molecule suggest that one (linked to iodine) is formally uncharged, while the other is partially oxidized. This latter ring is heavily coordinated through S- - -N linkages to neighboring CN2S2 rings and pyridine. Magnetic susceptibility measurements on [P-2,6-S]2[I] indicate that it is diamagnetic below 220 K.
Biological pretreatment of a chemical plant wastewater in high-rate moving bed biofilm reactors (1999)

The Moving Bed Biofilm Reactor (MBBR), where the biomass is attached to small plastic carrier elements that move freely along with the water in the reactors, has been tested for biological pretreatment of a complex chemical industry wastewater. The MBBRs were tested at organic loads up to 53 g BOD 5 /m 2 d and always removed the easily biodegradable BOD fraction, ranging from about 60 to 80%. At organic loads from 10 to 20 g BOD 5 /m 2 d slowly biodegradable organic matter was also metabolized, sometimes removing more than 95% BOD 5 . After polishing in an activated sludge unit, the final effluent had an average concentration of only 3.4 mg filtered BOD 5 /l. With a very high specific biofilm surface area, MBBRs followed by activated sludge offer a compact process combination for complete biological treatment of chemical industry wastewaters.
Modulable and Highly Diastereoselective Carbometalations of Cyclopropenes (2014)

Abstract Invited for the cover of this issue is the group of Ilan Marek at Technion–Israel Institute of Technology. The image depicts how cyclopropenes can be used to access to a variety of small, quaternary carbon‐bearing chiral building blocks. Read the full text of the article at 10.1002/chem.201303569 .
Antiangiogenic-Like Properties of Fermented Extracts of Ayurvedic Medicinal Plants (2015)

The three ayurvedic medicinal plants, Withania somnifera, Emblica officinalis, and Bacopa monnieri, were extracted by high-pressure static extraction using the Zippertex(®) technology. The extracts were mixed to reach quantifiable amounts of active compounds identified by high-pressure liquid chromatography-mass spectrometry (HPLC-MS) analysis. The mixture of extracts was incubated with resting cells of the fungus Beauveria bassiana ATCC 7159. The fermentation promoted the fluidization of the starting dense mixture, while HPLC monitoring evidenced the disappearance of glucogallin from E. officinalis extract and the concomitant increase in gallic acid content. Topical exposure of the chick embryo chorioallantoic membrane (CAM) to the nonfermented extract led to the extensive necrosis and destruction of the treated membrane. However, the fermented extract was shown to be free of any toxicity. Furthermore, compared with the untreated CAM, the fermented sample reduced CAM vascularization, suggesting its antiangiogenic potency. The innocuity of the fermented extract was demonstrated using the in vivo LD50 test, the morphological examination of internal organs of treated rats, as well as the evaluation of blood biomarkers of liver damage (aspartate aminotransferase and alanine aminotransferase). The fermented extract was developed as a nutraceutical antiangiogenic treatment of age-related macular degeneration and commercialized in an oral form named Ethnodyne-Visio™.