gebhart/patrepeval huggingface dataset:
Induction motor torque estimation accuracy using motor terminal variables (2017)

Information about tlie torque produced by an electrical motor is needed in many applications such as hybrid drivetrains and in some applications where the shaft torque cannot be measured directly e.g. because of vibrations or other physical limitations. This paper investigates the torque determination accuracy using the voltage and current time domain data obtained from motor terminals using a power analyzer. The calculated torque values are compared with the measured values obtained with a state-of-the-art torque transducer. The results are analyzed in 16 different operating points with torque values of 25%, 50%, 75% and 100% of motor rated torque and supply frequency values of 25%, 50%, 75% and 100% of rated motor frequency. Measurement results with a sinusoidal generator supply and a converter PWM supply are used in the comparison.
RECON-a tool for incident detection, tracking and response (2002)

Recent discussions on the state of Intrusion Detection Systems and Network Security Tools has prompted the notion that what is needed is a solution that can fuse data from heterogeneous distributed network and host sensors; supports sophisticated analysis models and automated responses; provides the user with the appropriate 'situational awareness' so that efforts can be focussed on the right problems; is "enterprise-aware". This paper presents some key concepts for such a solution by describing a tool, code named RECON, which is a result of extensive research and prototyping performed on an adaptive network security management framework funded by DARPA. This research indicates that in order for RECON to satisfy the stated requirements, it would need a standard message format and protocol; an analytical engine such as a rule-base; a flexible and extensible architecture; a graphical user interface that provides a unified view of various levels of information; a language to capture 'enterprise' rules.
Treatment combining RU486 and Ad5IL-12 vector attenuates the growth of experimentally formed prostate tumors and induces changes in the sentinel lymph nodes of mice (2010)

Inclusion of RU486 may serve as a useful adjuvant when combined with proinflammatory tumor killing agents by enhancement of the immune response and alteration of the TSLN microenvironment.
EBV MicroRNAs in Primary Lymphomas and Targeting of <i>CXCL-11</i> by ebv-mir-BHRF1-3 (2008)

EBV-encoded microRNAs (miRNAs) have been identified and their functions are being studied. The expression pattern of these miRNAs in clinical samples of EBV-associated non-Hodgkin's lymphomas is unknown. We analyzed five primary "endemic" pediatric Burkitt's lymphomas (BL), two acquired immunodeficiency syndrome (AIDS)-related type I latency BL lines, a type III latency line, three EBV(+) primary effusion lymphomas (PEL), and three AIDS-related diffuse large B-cell lymphomas (DLBCL) for expression of EBV-encoded miRNAs. A markedly elevated expression of miRNA BHRF1-3 in type III relative to its parental type I BL line was found. Primary unmanipulated type I BLs and EBV(+) PELs expressed high levels of BART2 miRNA, whereas DLBCLs expressed both BART2 and BHRF1-3 species. BHRF1-3 miRNA expression inversely correlated with levels of a putative cellular target, the IFN-inducible T-cell attracting chemokine CXCL-11/I-TAC, and suppression of this factor was reversed by transfection of an antisense oligo to the EBV miRNA BHRF1-3. EBV-encoded miRNAs are expressed in primary lymphomas classically linked to the virus and are associated with the viral latency status. Targeted suppression of CXCL-11/I-TAC by a viral-encoded miRNA may serve as an immunomodulatory mechanism in these tumors.
Optoacoustic diagnostic modality: from idea to clinical studies with highly compact laser diode-based systems (2017)

Optoacoustic (photoacoustic) diagnostic modality is a technique that combines high optical contrast and ultrasound spatial resolution. We proposed using the optoacoustic technique for a number of applications, including cancer detection, monitoring of thermotherapy (hyperthermia, coagulation, and freezing), monitoring of cerebral blood oxygenation in patients with traumatic brain injury, neonatal patients, fetuses during late-stage labor, central venous oxygenation monitoring, and total hemoglobin concentration monitoring as well as hematoma detection and characterization. We developed and built optical parametric oscillator-based systems and multiwavelength, fiber-coupled highly compact, laser diode-based systems for optoacoustic imaging, monitoring, and sensing. To provide sufficient output pulse energy, a specially designed fiber-optic system was built and incorporated in ultrasensitive, wideband optoacoustic probes. We performed preclinical and clinical tests of the systems and the optoacoustic probes in backward mode for most of the applications and in forward mode for the breast cancer and cerebral applications. The high pulse energy and repetition rate allowed for rapid data acquisition with high signal-to-noise ratio from cerebral blood vessels, such as the superior sagittal sinus, central veins, and peripheral veins and arteries, as well as from intracranial hematomas. The optoacoustic systems were capable of automatic, real-time, continuous measurements of blood oxygenation in these blood vessels.
The Brain at High Altitude: Hypometabolism as a Defense against Chronic Hypoxia? (1994)

The brain of hypoxia-tolerant vertebrates is known to survive extreme limitations of oxygen in part because of very low rates of energy production and utilization. To assess if similar adaptations may be involved in humans during hypoxia adaptation over generational time, volunteer Quechua natives, indigenous to the high Andes between about 3,700 and 4,900 m altitude, served as subjects in positron emission tomographic measurements of brain regional glucose metabolic rates. Two metabolic states were analyzed: (a) the presumed normal (high altitude-adapted) state monitored as soon as possible after leaving the Andes and (b) the deacclimated state monitored after 3 weeks at low altitudes. Proton nuclear magnetic resonance spectroscopy studies of the Quechua brain found normal spectra, with no indication of any unusual lactate accumulation; in contrast, in hypoxia-tolerant species, a relatively large fraction of the glucose taken up by the brain is released as lactate. Positron emission tomographic measurements of [18F]2-deoxy-2-fluoro-D-glucose (FDG) uptake rates, quantified in 26 regions of the brain, indicated systematically lower region-by-region glucose metabolic rates in Quechuas than in lowlanders. The metabolic reductions were least pronounced in primitive brain structures (e.g., cerebellum) and most pronounced in regions classically associated with higher cortical functions (e.g., frontal cortex). These differences between Quechuas with lifetime exposure to hypobaric hypoxia and lowlanders, which seem to be expressed to some degree in most brain regions examined, may be the result of a defense adaptation against chronic hypoxia.
Nanocrystalline graphene at high temperatures: insight into nanoscale processes (2019)

During high temperature pyrolysis of polymer thin films, nanocrystalline graphene with a high defect density, active edges and various nanostructures is formed. The catalyst-free synthesis is based on the temperature assisted transformation of a polymer precursor. The processing conditions have a strong influence on the final thin film properties. However, the precise elemental processes that govern the polymer pyrolysis at high temperatures are unknown. By means of time resolved <i>in situ</i> transmission electron microscopy investigations we reveal that the reactivity of defects and unsaturated edges plays an integral role in the structural dynamics. Both mobile and stationary structures with varying size, shape and dynamics have been observed. During high temperature experiments, small graphene fragments (nanoflakes) are highly unstable and tend to lose atoms or small groups of atoms, while adjacent larger domains grow by addition of atoms, indicating an Ostwald-like ripening in these 2D materials, besides the mechanism of lateral merging of nanoflakes with edges. These processes are also observed in low-dose experiments with negligible electron beam influence. Based on energy barrier calculations, we propose several inherent temperature-driven mechanisms of atom rearrangement, partially involving catalyzing unsaturated sites. Our results show that the fundamentally different high temperature behavior and stability of nanocrystalline graphene in contrast to pristine graphene is caused by its reactive nature. The detailed analysis of the observed dynamics provides a pioneering overview of the relevant processes during ncg heating.
Paperclickers: Affordable solution for classroom response systems (2020)

Abstract We propose paperclickers, a low‐cost classroom response system requiring a single mobile device for the teacher and cards with printed codes for the students, which results in a low‐cost, easy‐to‐deploy solution that aims at broadening the adoption of active learning techniques in developing countries. We implemented paperclickers as a smartphone application, whose development history, with pitfalls and lessons learned, we describe in this paper. We also describe the results of the first round of usability tests we performed on the first prototype, indicating the feasibility of paperclickers, the opportunities for design improvement, and how they affected the current version of the software. A beta release of paperclickers is available for the public.
Supplementary Figure 2 from Down-regulation of Suppressor of Cytokine Signaling-3 Causes Prostate Cancer Cell Death through Activation of the Extrinsic and Intrinsic Apoptosis Pathways (2023)

Supplementary Figure 2 from Down-regulation of Suppressor of Cytokine Signaling-3 Causes Prostate Cancer Cell Death through Activation of the Extrinsic and Intrinsic Apoptosis Pathways
Improving osteoblast growth through BMP-7 short peptides (2007)

Osteoblasts are mononuclear cells that are responsible for bone formation and mineralization of an osteoid matrix. Osteoblasts arise when osteoprogenitor cells are induced to differentiate under the influence of growth factors, particularly bone morphogenetic proteins (BMPs). So BMPs are very important for the regeneration of bone and cartilage. Especially, BMP-2 and BMP-7 are the most commonly used growth factors to improve osteoblast functions. However, the precise receptor-binding region for promoting osteoblast growth in BMPs has not been identified. Many researchers try to use short peptides to improve the growth of osteoblasts instead of the entire BMP molecule. Here, we report that some short peptides, according to residues 101∽130 of the BMP-7 sequence, increase the growth of osteoblasts. As a result, peptide-b (KPSSAPTQLN) was known to increase the number of osteoblasts, as well as improve their shape.
Estimating Transformations for Regression via Additivity and Variance Stabilization (1988)

Abstract I propose a method for the nonparametric estimation of transformations for regression. It is much more flexible than the familiar Box-Cox procedure, allowing general smooth transformations of the variables, and is similar to the ACE (alternating conditional expectation) algorithm of Breiman and Friedman (1985). The ACE procedure uses scatterplot smoothers in an iterative fashion to find the maximally correlated transformations of the variables. Like ACE, my proposal can incorporate continuous, categorical, or periodic variables, or any mixture of these types. The method differs from ACE in that it uses a (nonparametric) variance-stabilizing transformation for the response variable. The technique seems to alleviate many of the anomalies that ACE suffers with regression data, including the inability to reproduce model transformations and sensitivity to the marginal distribution of the predictors. I provide several examples, including an analysis of the “brain and body weight” data and some data on telephone-call load. I also discuss the relationship of the proposed technique to the Box-Cox and ACE procedures. Efron's work on transformations provides some of the theoretical basis for the methodology.
Versatile padding schemes for joint signature and encryption (2004)

We propose several highly-practical and optimized constructions for joint signature and encryption primitives often referred to as <i>signcryption</i>. All our signcryption schemes, built directly from trapdoor permutations such as RSA, share features such as simplicity, efficiency, generality, near-optimal exact security, flexible and ad-hoc key management, key reuse for sending/receiving data, optimally-low message expansion, "backward" use for plain signature/encryption, long message and associated data support, the strongest-known qualitative security and, finally, complete compatibility with the PKCS#1 infrastructure.
Abstract 2973: Establishment of organoids and patient derived cancer cell lines from gastric cancer body fluids as preclinical models for personalized therapy (2021)

Abstract Gastric cancer (GC), the second leading cause of cancer-related deaths worldwide, is especially prevalent in Asian countries. Despite advances in therapeutics, GC patients with peritoneal metastasis is frequent and when ascites has developed, the prognosis is very poor. Also, the number of anticancer drugs successfully marketed is rare in GC. Therefore, a faithfully in vitro model that can test various drugs and perform patient-specific personalized therapy is needed. We isolated cancer cells from ascites or pleural fluids of gastric cancer patients and established 19 patient-derived organoids and matched patient-derived cancer cell lines (PDCC). Organoid success rate was 60.7 % while PDCC was about 28.5 %. The time required to establish organoids was 1-2 months, while PDCC was 3-4 months. Organoids showed various growth characteristics and morphology, which reflects the clinical behavior of the patients including adenocarcinoma or signet ring cell carcinoma. In addition, drug-sensitive to each organoid and matched PDCC were identified using various chemotherapeutics and targeted agents. Then, patients' clinical information and comparative analysis were performed, suggesting the potential sensitive drug to each patient. Currently, the genetic information of each organoid is ongoing with WES/RNA Seq, and the sensitivity and comparative analysis of the drug will be performed. Therefore, our results provide a potential infrastructure for personalized therapy by comprehensive analysis of the patient's genomic data and organoid/PDCC model. Citation Format: Sun Kyoung Kang, Hyun Joo Bae, Woo Sun Kwon, Tae Soo Kim, Sujin Lee, Sang Woo Cho, Hyun Cheol Chung, Sun Young Rha. Establishment of organoids and patient derived cancer cell lines from gastric cancer body fluids as preclinical models for personalized therapy [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2021; 2021 Apr 10-15 and May 17-21. Philadelphia (PA): AACR; Cancer Res 2021;81(13_Suppl):Abstract nr 2973.
Rate constant determination of the reaction of metastable atomic nitrogen(2D,2P) with nitrogen dioxide using moderated nuclear recoil atoms (1986)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTRate constant determination of the reaction of metastable atomic nitrogen(2D,2P) with nitrogen dioxide using moderated nuclear recoil atomsRen Iwata, Richard A. Ferrieri, and Alfred P. WolfCite this: J. Phys. Chem. 1986, 90, 25, 6722–6726Publication Date (Print):December 1, 1986Publication History Published online1 May 2002Published inissue 1 December 1986https://pubs.acs.org/doi/10.1021/j100283a027https://doi.org/10.1021/j100283a027research-articleACS PublicationsRequest reuse permissionsArticle Views65Altmetric-Citations11LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
P45 Forms a Complex with FADD and Promotes Neuronal Cell Survival Following Spinal Cord Injury (2013)

Fas-associated death domain (DD) adaptor (FADD), a member of the DD superfamily, contains both a DD and a death effector domain (DED) that are important in mediating FAS ligand-induced apoptotic signaling. P45 is a unique member of the DD superfamily in that it has a domain with sequence and structural characteristics of both DD and DED. We show that p45 forms a complex with FADD and diminishes Fas-FADD mediated death signaling. The DED of FADD is required for the complex formation with p45. Following spinal cord injury, transgenic mice over-expressing p45 exhibit increased neuronal survival, decreased retraction of corticospinal tract fibers and improved functional recovery. Understanding p45-mediated cellular and molecular mechanisms may provide insights into facilitating nerve regeneration in humans.
Chronic Stress Accelerates Atherosclerosis in the Apolipoprotein E Deficient Mouse (2003)

Conventional cardiovascular risk factors such as cholesterol and blood pressure do not account fully for variation in coronary heart disease suggesting the involvement of additional mechanisms. We have examined the effects of a chronic psychological stress protocol on the development of atherosclerosis in the apolipoprotein E knockout mouse. We observed a 3-fold increase in staining for atheroma accompanied by a 10-fold increase in corticosterone concentrations in mice stressed for 12 weeks. These data suggest that chronic mild stress can induce or accelerate the development of atherosclerosis.
A novel polymer for potential use in a trileaflet heart valve (2006)

A novel polyolefin, poly(styrene-b-isobutylene-b-styrene) (Quatromer), is being proposed as a viable polymer for use in trileaflet heart valves because of its oxidative stability. The current study was designed to assess the polymer's hemocompatibility and mechanical durability. Mechanical characterization included static tensile tests and dynamic tension-tension and bending fatigue tests, where the properties of isotropic and composite (polypropylene (PP) embedded) Quatromer specimens were compared with those of a polyurethane (PUR) approved for cardiovascular applications. It was found that by embedding PP fibers into the Quatromer matrix, the tensile and fatigue properties of the polymer could be improved, making them comparable, if not better than the PUR. The thrombotic potential of Quatromer was compared with the PUR, glutaraldehyde-fixed porcine valve material, and a positive and negative control by measuring platelet deposition with radiolabeled platelets in a parallel plate flow configuration. The porcine valve material was found to have significantly higher platelet deposition under all flow regimes, while no significant difference existed between Quatromer and PUR. In conclusion, Quatromer is shown to have suitable hemocompatibility and mechanical durability for use in polymer trileaflet heart valves, and fiber reinforcement can effectively be used to tailor the mechanical properties.
Towards ASR Based on Hierarchical Posterior-Based Keyword Recognition (2006)

The paper presents an alternative approach to automatic recognition of speech in which each targeted word is classified by a separate binary classifier against all other sounds. No time alignment is done. To build a recognizer for N words, N parallel binary classifiers are applied. The system first estimates uniformly sampled posterior probabilities of phoneme classes, followed by a second step in which a rather long sliding time window is applied to the phoneme posterior estimates and its content is classified by an artificial neural network to yield posterior probability of the keyword. On a small vocabulary ASR task, the system still does not reach the performance of the state-of-the-art system but its conceptual simplicity, the ease of adding new target words, and its inherent resistance to out-of-vocabulary sounds may prove significant advantage in many applications
Distributed Multiple Access Protocols and Real-Time Communication (1983)

In the past 10 years the field of distributed multiple access communication has developed into a major area of both practical and theoretical interest within the field of computer communications. The multiple access problem arises from the necessity of sharing a single communication channel among a community of distributed users. The distributed algorithm used by the stations to share the channel is known as the multiple access protocol. This paper examines the multiple access problem and various approaches towards its resolution. This survey first defines the multiple access problem and then presents the underlying issues and difficulties in multiple access communication. A taxonomy for multiple access protocols is then developed in order to characterize common approaches and to provide a framework in which these protocols can be compared and contrasted. Different proposed protocols are then described and discussed and aspects of their performance are examined The use of multiple access protocols for "real-time" or "time-constrained" communication applications, such as voice transmission, is examined next. Issues in real-time communication are identified and recent work in the design of real-time multiple access protocols is surveyed.
Real-time two-photon lithography in controlled flow to create a single-microparticle array and particle-cluster array for optofluidic imaging (2017)

Microarray technology provides an excellent platform for biomedical and biochemical research including basic scientific studies, drug discovery, and diagnostics. Here, we develop a novel method referred to as real-time two-photon lithography in a controlled flow in which femtosecond laser two-photon lithography is performed in situ in the sequential mode stopping and flowing the flow of liquid resin containing microparticles to achieve 100% trapping on a one-bead-to-one-trap basis. Polydisperse particles can be all trapped to form a desired array by freely designing trap structures, resulting in an unprecedentedly high capture efficiency of ∼100%. No persistent pressure is needed after trapping which reduces the complexity of the system. In addition, trapping of particle-cluster arrays with a controlled number of particles is also achieved via this method. The trapped particles inside the microchip are successfully applied as microlenses for high quality imaging. The present technology marks an essential step towards a versatile platform for the integration of bead-based assays and paves the way for developing innovative microfluidics, optofluidics, micro-optics and single-cell analysis devices.