gebhart/patrepeval huggingface dataset:
Algal biomass valorization for biofuel production and carbon sequestration: a review (2022)

Abstract The world is experiencing an energy crisis and environmental issues due to the depletion of fossil fuels and the continuous increase in carbon dioxide concentrations. Microalgal biofuels are produced using sunlight, water, and simple salt minerals. Their high growth rate, photosynthesis, and carbon dioxide sequestration capacity make them one of the most important biorefinery platforms. Furthermore, microalgae's ability to alter their metabolism in response to environmental stresses to produce relatively high levels of high-value compounds makes them a promising alternative to fossil fuels. As a result, microalgae can significantly contribute to long-term solutions to critical global issues such as the energy crisis and climate change. The environmental benefits of algal biofuel have been demonstrated by significant reductions in carbon dioxide, nitrogen oxide, and sulfur oxide emissions. Microalgae-derived biomass has the potential to generate a wide range of commercially important high-value compounds, novel materials, and feedstock for a variety of industries, including cosmetics, food, and feed. This review evaluates the potential of using microalgal biomass to produce a variety of bioenergy carriers, including biodiesel from stored lipids, alcohols from reserved carbohydrate fermentation, and hydrogen, syngas, methane, biochar and bio-oils via anaerobic digestion, pyrolysis, and gasification. Furthermore, the potential use of microalgal biomass in carbon sequestration routes as an atmospheric carbon removal approach is being evaluated. The cost of algal biofuel production is primarily determined by culturing (77%), harvesting (12%), and lipid extraction (7.9%). As a result, the choice of microalgal species and cultivation mode (autotrophic, heterotrophic, and mixotrophic) are important factors in controlling biomass and bioenergy production, as well as fuel properties. The simultaneous production of microalgal biomass in agricultural, municipal, or industrial wastewater is a low-cost option that could significantly reduce economic and environmental costs while also providing a valuable remediation service. Microalgae have also been proposed as a viable candidate for carbon dioxide capture from the atmosphere or an industrial point source. Microalgae can sequester 1.3 kg of carbon dioxide to produce 1 kg of biomass. Using potent microalgal strains in efficient design bioreactors for carbon dioxide sequestration is thus a challenge. Microalgae can theoretically use up to 9% of light energy to capture and convert 513 tons of carbon dioxide into 280 tons of dry biomass per hectare per year in open and closed cultures. Using an integrated microalgal bio-refinery to recover high-value-added products could reduce waste and create efficient biomass processing into bioenergy. To design an efficient atmospheric carbon removal system, algal biomass cultivation should be coupled with thermochemical technologies, such as pyrolysis.
Impedance Matching Probes for Wireless Applications (1995)

This work describes the motivation, technology, design, and performance of impedance matching probes that address the needs of wireless applications. The impedance matching solution can be implemented in two distinctly different technologies, air-coplanar and thin-film membrane. Impedance matched probes offer improved load-pull characterization of power, gain and efficiency, and accurate characterization of devices with non-standard impedances.
Novel simian foamy virus infections from multiple monkey species in women from the Democratic Republic of Congo (2012)

Our study documents SFV infection in rural DRC for the first time and identifies infections with novel SFV variants from Colobus and red-tailed monkeys. Unlike previous studies, women were not at lower risk for SFV infection in our population, providing opportunities for spread of SFV both horizontally and vertically. However, limited testing of close contacts of WB-positive persons did not identify human-to-human transmission. Combined with the broad behavioral risk and distribution of NHPs across DRC, our results suggest that SFV infection may have a wider geographic distribution within DRC. These results also reinforce the potential for an increased SFV prevalence throughout the forested regions of Africa where humans and simians co-exist. Our finding of endemic foci of SFV infection in DRC will facilitate longitudinal studies to determine the potential for person-to-person transmissibility and pathogenicity of these zoonotic retroviral infections.
Enhancing the vanadium redox flow battery efficiency by adjusting the electrode configuration (2020)

The vanadium redox flow battery (VRFB) is being investigated as one of the promising candidates for large-scale energy storage systems. In the present work, the role of electrode shape on a single VRFB cell performance has been studied through a 3D numerical model. The model accounts for the coupling between electrochemistry and fluid mechanic physics. Seven cases of electrode configurations at the same volume size (10 cm<sup>3</sup>) have been simulated to investigate the overall battery performance. Results from the simulation show that the configuration (case 7) has the best battery efficiency, while the worse one is (case 4) under the same operating conditions, e.g., 71.72% and 63.82%, respectively. Also, the ratio of output to input power for (case 7) is 0.72, while 0.63 for (case 4). In addition, there is an optimal flow rate for each case to get maximum battery efficiency, which means a balance between electrochemical reactions and pumping losses is required. Overall, adopting a thicker electrode (cases 2, 3 and 4) results in lower battery performance due to the poor voltage responses. One feature of the introduced model is its capability to predict the performance of most flow batteries cell configurations.
Bioprosthetic heart valves: the need for a quantum leap (2004)

More than 250,000 bioprosthetic heart valves are being implanted annually. Although the majority of recipients are elderly developed-world patients, the most urgent need for tissue valves is in younger patients, where rapid degeneration of contemporary prostheses remains a serious obstacle. After decades of empirical and mostly futile attempts to extend the longevity of tissue valve prostheses, new insights and solutions are on the horizon. Aetiologically, a shift of focus from mineralization to immune responses and inflammation emerges. On the development side, new engineering approaches to both selective extraction of tissue components and cross-links are increasingly defining the new direction. In order to dramatically improve the performance of bioprosthetic heart valves, these new developments need to lead to a broad consensus for a paradigm shift in a hitherto rather stagnant field of medical research.
[PP.25.43] CHANGES OF INTRINSIC STIFFNESS OF THE CAROTID ARTERIAL WALL DURING THE CARDIAC CYCLE MEASURED BY SHEAR WAVE ELASTOGRAPHY IN HYPERTENSIVES COMPARED TO NORMOTENSIVES (2017)

Objective: The question whether arterial stiffness in hypertension is increased solely because of increased arterial pressure is not solved. Because measurement of arterial stiffness is highly dependent on measurement of blood pressure (BP), the development of methods independent of BP is necessary for clarifying this question. Shear wave elastography (SWE, Supersonic Imagine, Aix-en-Provence, France) is an ultrasound technique which enables to quantitatively assess local tissue stiffness by remotely generating transient shear waves into the tissue (push mode) and tracking their propagation using a very fast sampling rate (up to 10 kHz). The elastic modulus of the material is directly related to the speed of the shear waves, with no need of BP. This method has never been tested against classical echotracking (Artlab, Esaote, Maastricht, NL) and carotid to femoral pulse wave velocity (cf-PWV, Sphygmocor, AtCor, Sydney, Australia). Design and method: We included 25 subjects, 14 normotensives (NT) and 11 essential hypertensives (HT), matched for age and sex. We compared SWE to echotracking and cf-PWV. We optimized SWE algorithms for carotid wall tracking and shear wave group velocity calculation for the anterior (a-SWV) and posterior wall (p-SWV). 8 ultrasonic pushes were triggered at intervals of 200 ms in order to study the variations of stiffness during the cardiac cycle. Results: p-SWV showed no association with carotid PWV, cf-PWV nor BP. Mean a-SWV over the cardiac cycle is strongly associated with carotid PWV measured by Echotracking (r = 0.56, p = 0.003) and cf-PWV (r = 0.66, p < 0.001). a-SWV strongly increases with BP level during the cardiac cycle (p < 10–6). Similar associations between a-SWV and BP were found in NT and HT although HT had higher values of a-SWV throughout all BP levels. However, when a common BP value (100 mmHg) was considered, no significant difference was found between NT and HT, therefore showing that the wall intrinsic material stiffness is not increased in HT. Conclusions: We have demonstrated with a method independent of BP that the increased arterial stiffness in HT is entirely due to the BP increase. SWE appears as a promising technique for assessing arterial stiffness.
Soft Microscopy: Strategies for Contrast Enhancement of Macromolecules (2020)

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Pervasive Surveillance and Privacy (2022)

The aim of this special issue is to discuss pervasive surveillance and privacy risks, surveillance detection approaches, surveillance and counterveillance, and privacy- enhancing approaches to thwart surveillance attempts. The accepted papers address a variety of topics, ranging from privacy preserving technologies to literature reviews to identify promising research directions.
Deep Convolutional Denoising of Low-Light Images (2017)

Poisson distribution is used for modeling noise in photon-limited imaging. While canonical examples include relatively exotic types of sensing like spectral imaging or astronomy, the problem is relevant to regular photography now more than ever due to the booming market for mobile cameras. Restricted form factor limits the amount of absorbed light, thus computational post-processing is called for. In this paper, we make use of the powerful framework of deep convolutional neural networks for Poisson denoising. We demonstrate how by training the same network with images having a specific peak value, our denoiser outperforms previous state-of-the-art by a large margin both visually and quantitatively. Being flexible and data-driven, our solution resolves the heavy ad hoc engineering used in previous methods and is an order of magnitude faster. We further show that by adding a reasonable prior on the class of the image being processed, another significant boost in performance is achieved.
ChemInform Abstract: THE USE OF THE 2,4‐DINITROPHENYL GROUP IN SUGAR CHEMISTRY RE‐EXAMINED (1981)

Abstract Die 2,4‐Dinitrophenylgruppe kann in verschiedene Positionen von Zuckern, einschließ‐ lich der anomeren Zentren, mittels des Reagenzes (VI) und DABCO (VII) eingeführt werden: Aus den Zuckerderivaten (Ia), (IIa), (IIIa) [oe/ß‐Anomerengemisch (AG.)], (IVa) (AG.) bzw. (Va) (AG.) werden so die Derivate (Ib), (IIb) bzw. (IIIb), (IVb), (Vb) (jeweils ausschließlich β‐Anomeres) erhalten.
Type‐safe casting (1998)

Many modern extensible systems, such as Java and the SPIN operating system, depend on type safety for memory protection. Unfortunately, current type-safe languages do not support systems programming well, because they do not give programmers the ability to deal with untyped data easily. In particular, they do not support the ability to cast between untyped data and language-level types. We describe a powerful, type-safe cast operator that helps programmers write low-level systems codes in type-safe languages. We have implemented this operator in Modula-3 for the SPIN operating system, and we give specific examples of how we use it in SPIN. © 1998 John Wiley & Sons, Ltd.
Synthesis, Growth, and Er<sup>3+</sup> Luminescence of Lanthanide Phosphate Nanoparticles. (2003)

Abstract For Abstract see ChemInform Abstract in Full Text.
Resolving the lineage relationship between malignant cells and vascular cells in glioblastomas (2022)

Glioblastoma multiforme (GBM), a highly malignant and heterogeneous brain tumor, contains various types of tumor and non-tumor cells. Whether GBM cells can trans-differentiate into non-neural cell types, including mural cells or endothelial cells (ECs), to support tumor growth and invasion remains controversial. Here we generated two genetic GBM models de novo in immunocompetent mouse brains, mimicking essential pathological and molecular features of human GBMs. Lineage-tracing and transplantation studies demonstrated that, although blood vessels in GBM brains underwent drastic remodeling, evidence of trans-differentiation of GBM cells into vascular cells was barely detected. Intriguingly, GBM cells could promiscuously express markers for mural cells during gliomagenesis. Furthermore, single-cell RNA sequencing showed that patterns of copy number variations (CNVs) of mural cells and ECs were distinct from those of GBM cells, indicating discrete origins of GBM cells and vascular components. Importantly, single-cell CNV analysis of human GBM specimens also suggested that GBM cells and vascular cells are likely separate lineages. Rather than expansion owing to trans-differentiation, vascular cell expanded by proliferation during tumorigenesis. Therefore, cross-lineage trans-differentiation of GBM cells is very unlikely to occur during gliomagenesis. Our findings advance understanding of cell lineage dynamics during gliomagenesis, and have implications for targeted treatment of GBMs.
PCD1, a novel gene containing PDZ and LIM domains, is overexpressed in several human cancers. (2000)

In an effort to discover novel genes differentially expressed in human pancreatic cancer, we have identified a gene named PCD1 (pancreatic cancer derived) that is up-regulated in pancreatic dysplasia and cancer relative to normal pancreatic ductal epithelium. We cloned the full length (4572 bp) of this gene, which encodes a novel protein of 1064 amino acids containing a PDZ domain and a LIM domain. An alternatively spliced form with a deletion of 30 bp in the coding region was also found. In situ hybridization results showed that PCD1 is highly expressed in a significant percentage of colon, breast, liver, lung, pancreas, stomach, and prostate tumor tissues but is expressed in very few normal tissues. Northern blot hybridization confirmed the overexpression of PCD1 in colon and breast tumor tissues and also showed strong expression of PCD1 in the heart as well as in HeLa cells. Real-time quantitative reverse transcription-PCR verified the overexpression of PCD1 in primary colon tumors or in liver metastases relative to normal colon tissues in five of eight patients. The PCD1 gene maps to human chromosome 13q21.33. Because of its high levels of expression in neoplastic tissues and the presence of both PDZ and LIM domains, we suggest that PCD1 may play an important role in cytoskeletal reorganization during carcinogenesis.
Effect of Superplasticizer Dosage on Workability and Strength Characteristics of Concrete (2016)

The use of chemical admixtures in concrete is a common solution to achieve full compaction particularly where reinforcement congestion and shortage of skilled workers. The past researchers have been underscored the use of chemical admixtures imparts the desirable properties to concrete in both fresh and hardened state. This paper has been made an attempt to study the influence of superplasticizer dose of 400ml, 600ml, 800ml, 1000ml and 1200ml/100 kg of cement on performance of Concrete. The experimental tests for fresh and hardened properties of concrete for three mixes of 30 MPa grade are studied and the results are compared with normal concrete. The tests considered for study are, slump test, slump loss, flow table and compressive strength test The results show that for the constant water cement ratio, increase of superplasticizer dose in properties of concrete leads to gain of good workability. Moreover, there is also increase in compressive strength than that of normal concrete mix.
Electromigration Oscillations Occurring in Ternary Electrolyte Systems with Complex Eigenmobilities, as Predicted by Theory and Ascertained by Capillary Electrophoresis (2009)

Chemical oscillations are driven by a gradient of chemical potential and can only develop in systems where the substances are far from chemical equilibrium. We have discovered a new analogous type of oscillations in ternary electrolyte mixtures, which we call electromigration oscillations. They appear in liquid solutions of electrolytes and are associated with the electromigration movement of ions when conducting an electric current. These electromigration oscillations are driven by the electric potential gradient, while the system can be close to chemical equilibrium. The unequivocal criterion for the instability of the electrolyte solution and its ability to oscillate is the existence of complex system eigenmobilities. We show how to calculate the system eigenmobilities by utilizing the linear theory of electromigration and how to identify the complex system eigenmobilities to predict electromigration oscillations. To experimentally prove these electromigration oscillations, we employ a commercially available instrument for capillary electrophoresis. The oscillations start a certain period of time after switching on the driving electric current. The axial concentration profiles of the electrolytes in the capillary attain a nearly periodic pattern with a spatial period in the range of 1-4 mm, with almost constant amplitude. This periodic pattern moves in the electric field with mobility that is equal to the real part of the complex eigenmobility pair. We have found several ternary oscillating electrolytes composed of a base and two acids, of which at least one has higher valence than one in absolute value. All the systems have three system eigenmobilities: one is real and close to zero, and the two others form the complex conjugate pair, the real part of which is far from zero.
Characterization of carbon structures produced by graphene self-assembly (2014)

Low-dimensional carbon-based materials, in particular two-dimensional graphenic carbon structures, have been produced from single-walled carbon nanotube disruption using high-shear mixing and/or treatments in sulfonitric acid mixtures at both room and high temperature. Among other two-dimensional graphenic carbon structures, colloidal dispersions of graphenic nanoflakes have been obtained. Different structural arrangements, resulting from the reorganization of carbon because of the disruption procedures applied, were observed through selected area electron diffraction (SAED) and through reflection high-energy electron diffraction (RHEED) analyses coupled to transmission and scanning electron microscopy observations. Such combined investigations in the real and reciprocal space provided structural information at the nanoscale on the clustering of graphene layers in nanoplatelets or/and on their assembly into highly ordered (single-crystal) nanosheets. Furthermore, a different carbon phase exhibiting an orthorhombic cell with Cmma symmetry has been detected by SAED and RHEED analyses. In addition, a variety of self-assemblies of hexagonal basal planes have been observed to occur as the result of their different rotational and/or translational stacking faults. Overall, the reported results contribute to define the conditions for a controlled self-assembly of graphene-based structures with tailored dimensions, which is an important technological challenge, as their structure at the nanoscale dramatically affects their electrical properties.
The future of male contraception: a fertile ground (2018)

The continued and rapid expansion of the Earth's population mandates the need for safe and effective measures of contraception. While a plethora of options exist for women, methods of contraception for the male partner are limited to condoms and vasectomy. The sequela of this discrepancy has led to the family planning burden falling disproportionately on the female partner. For the past several decades, extensive research has been undertaken exploring the feasibility of hormonal male contraception. This proposed method of contraception has focused on suppressing spermatogenesis by exploiting the hypothalamic-pituitary-gonadal (HPG) axis. Beginning with proof of concept studies in the early nineties, administration of testosterone in healthy male subjects has been shown to be an efficacious method of inducing sterility. Owing to ethnic differences in spermatogenesis suppression and the comparatively low rate of azoospermia in Caucasian men with androgen-only regimens, investigators have explored the addition of progestins to further enhance the efficacy of hormonal contraception. Though studies have revealed promise with androgen-progestin regimens, the lack of long-term studies has precluded the development of a marketable product. Recently, more research has been directed towards identifying non-hormonal alternatives to male contraception. These non-hormonal options have ranged from the development of devices facilitating reversible occlusion of the vas deferens lumen to medications disrupting various pathways in the process of spermatogenesis. Underlying the development of hormonal and non-hormonal strategies is the shared enthusiasm men and women have towards these male directed methods. The willingness of couples to pursue these alternatives combined with the global need to reduce the psychological and socioeconomic implications of unintended pregnancy ensures that research will continue to bring this goal to fruition.
Selective Localization of Hierarchically Assembled Particles to Plasma Membranes of Living Cells (2019)

Abstract Particles that preferentially partition to a specific cellular subunit, such as the nucleus, mitochondria, or the cytoskeleton, are of relevance to a number of applications, including drug delivery, genetic manipulation, or self‐assembly. Here, hierarchical assemblies of fully synthetic particles that selectively localize to the plasma membrane of mammalian cells are presented. A multimodal approach is used to create assemblies of polymer‐based carrier particles with amphiphilic gold nanoparticles immobilized on one hemisphere. These assemblies persist in the plasma membrane of cells for several days and undergo rearrangements and clustering, typically considered to be hallmarks of membrane‐bound receptors.
Cascade reactions for syntheses of heterocycles (2006)

Cascade reactions are useful method for the construction of polycyclic skeletons, which are important cores for biological activities. A variety of cascade reactions, carried out under multiple reaction conditions, such as pericyclic, polar, radical, and transition metal catalyzed reaction conditions, have been investigated. Novel methodologies, developed by us, and their applications are discussed.