gebhart/patrepeval huggingface dataset:
Assessing the overhead of authentication during SDN-enabled restoration of smart grid inter-substation communications (2018)

Since real-time and resilient recovery of link failures is crucial for power grid infrastructure to continue its services, emerging technologies such as Software Defined Networking (SDN) has started to be employed for such purposes. SDN switches can be remotely controlled to change their configurations by exploiting the wireless communication options. However, when wireless is to be used in Smart Grid communications, security and reliability become important issues due to the specific characteristics of wireless communications. This paper investigates the overhead of providing such services on wireless links when SDN is utilized. Specifically, we consider the establishment of authentication services when wireless back-up links (i.e., WiFi or LTE) are employed as a result of a reactive link failure detection mechanism. To the best of our knowledge, this work is the first to consider authentication of such an SDN-enabled Smart Grid inter-substation communication with WiFi and LTE. To be able to effectively evaluate the performance of this proposed SDN-enabled framework, we developed it in Mininet emulator. Since Mininet does not support the authentication services for WiFi or LTE, we proposed several novel extensions to Mininet by integrating it with ns-3 simulator that supports the LTE/WiFi protocol stacks. We conducted extensive experiments by considering a general application using Smart Grid Manufacturing Message Specification (MMS) standard to assess the recovery performance of the proposed secure SDN-enabled recovery system. The results show that when authentication and reliable protocols such as TCP are to be employed, the proposed framework can still meet the deadlines of 100 ms with WiFi while LTE misses only a few packets.
Effect of an Artificial RNA Marker on Gene Expression in <i>Escherichia coli</i> (2005)

Transcriptional analysis was used to examine the effect of a genomically encoded artificial RNA on Escherichia coli in rich and minimal media. Only the expression of a single gene, deoC, was unequivocally affected under both conditions. E. coli marker strains of this type may be useful in monitoring the fate and transport of bacteria in various applications.
Development of tilt servo system using 4-axis lens actuator for disk tilt compensation (1999)

High-Definition DVD 15 GB/side recording capacity is realized by using violet laser diodes, and it is expected to be the next generation optical disc. However, the shortening in the wavelength of laser diode and increase in recording density lead to a tighter margin for allowable disc tilt due to the wavefront aberration. Therefore, a tilt servo system using a 4-axis lens actuator has been developed. It controls the object lens not only in tracking and focusing directions but also in two axes tilt directions corresponding to disc tilt. This paper describes features of the tilt servo system and the experimental results of its tilt compensation effect.
Hyperspectral Image Super-resolution with Deep Priors and Degradation Model Inversion (2022)

To overcome inherent hardware limitations of hyperspectral imaging systems with respect to their spatial resolution, fusion-based hyperspectral image (HSI) super-resolution is attracting increasing attention. This technique aims to fuse a low-resolution (LR) HSI and a conventional high-resolution (HR) RGB image in order to obtain an HR HSI. Recently, deep learning architectures have been used to address the HSI super-resolution problem and have achieved remarkable performance. However, they ignore the degradation model even though this model has a clear physical interpretation and may contribute to improve the performance. We address this problem by proposing a method that, on the one hand, makes use of the linear degradation model in the data-fidelity term of the objective function and, on the other hand, utilizes the output of a convolutional neural network for designing a deep prior regularizer in spectral and spatial gradient domains. Experiments show the performance improvement achieved with this strategy.
Is There a Preferred Stroke Prevention Strategy for Diabetic Patients with Non-Valvular Atrial Fibrillation? Comparing Warfarin, Dabigatran and Rivaroxaban (2018)

In diabetic AF patients, dabigatran and rivaroxaban showed a superior or non-inferior effectiveness and safety profile compared with warfarin. Dabigatran was associated with a significantly lower risk of mortality than rivaroxaban.
Design of micron MOS switching devices (2007)

Summary form only only given, as follows. Modern photolithographic technology offers the capability of fabricating MOSFET devices of micron dimensions and less. It is by no means obvious that such small devices can be designed with suitable electrical characteristics for LSI switching applications. In this talk we will describe short-channel devices (L <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">eff</sub> ~ l μ) designed by scaling down larger devices with desirable electrical characteristics. Lateral and vertical dimensions, doping level, and operating voltages and currents are scaled in a self-consistent fashion. In this way small devices have been fabricated without the usual deleterious effects associated with short channels. The measured characteristics of these short-channel devices and the larger devices from which they were scaled will be compared. The scaling procedure helps to better understand the limitations of miniaturization of MOS devices. Significant problems are encountered when operating voltages become comparable to the band gap which cannot be scaled within the silicon technology. The subthreshold characteristic of the device then becomes an important consideration. [This reprint (and two more from 1973 and 1974) show the difference between conference and journal reporting in the 1970s. When the concept of scaling first saw the light of day at IEDM in 1972, only an abstract remained as an archive report. By 1973, the IEDM Digest provided a broader overview of Dennard's report. Dennard's 1974 explanation of scaling turned out to be the most cited article in the 51 year history of the JSSC, close to 700 times, according to the last count in 2005 by the independent citation report firm, Thomson ISI.]
Processing Speed Test (PST): A Self-Administered iPad®-Based Tool for Assessing MS-Related Cognitive Dysfunction (S33.001) (2014)

OBJECTIVE: To examine the relationship between performance on the Processing Speed Test (PST), an iPad®-based app for measuring cognition in MS, and self-reported fatigue, employment, and cognitive status. BACKGROUND: Cognitive dysfunction occurs in >50% of MS patients but is infrequently assessed in the clinic setting. The PST app is a self-administered test of information processing speed that simulates the technician-administered Symbol Digit Modalities Test (SDMT). The purpose of this study was to examine the validity of the PST in comparison to the SDMT. DESIGN/METHODS: Self-administered PST and technician-administered SDMT scores were derived from 51 MS patients representing a range of MS severity, and 40 age and gender-matched healthy controls (HC). Test-retest reliability, concurrent validity between PST and SDMT, sensitivity in distinguishing MS from HC participants, and relationship between PST and SDMT scores and self-reports of fatigue, work status, and cognitive performance were determined. RESULTS: We previously reported high levels of test-retest reliability and sensitivity for both the PST and SDMT; concurrent validity is also high, indicating the two measures are tapping comparable cognitive abilities. Scores on the PST and SDMT were significantly lower in unemployed MS patients compared to those working full- or part-time. On the NeuroQOL, a self-report measure of fatigue correlated significantly with PST (r=-0.34) and SDMT (r=-0.32), but neither PST nor SDMT correlated with two self-report cognitive measures. CONCLUSIONS: PST has favorable psychometric properties in comparison to SDMT and correlates equally well with SDMT in relationship to work status and fatigue. PST has several important advantages over SDMT: 1) cognitive performance data can be obtained without technician intervention, 2) unlike the SDMT, PST has multiple forms to minimize practice effects, and 3) additional measures (e.g., inter-response times and learning curves) can be computed that are not possible with the SDMT. Study Supported by: Novartis Pharmaceuticals and the National Multiple Sclerosis Society
Pragmatic Frequency Domain Equalization for Single Carrier with Offset Modulations (2013)

Offset signals can be designed to have reduced envelope fluctuations allowing high amplification efficiency. When combined with SC-FDE (Single-Carrier with Frequency-Domain Equalization) schemes, they become excellent candidates for broadband wireless systems with severe power constraints. However, the performance of these modulations with conventional FDE receivers is sub-par, even for receivers specifically designed for offset modulations. This is especially serious when large offset QAM (Quadrature Amplitude Modulation) constellations are used. In this paper we consider SC-FDE schemes combined with offset modulations and study the reason behind the poor performance of conventional FDE implementations. We also present pragmatic FDE receivers for offset modulations that have low complexity and excellent performance.
Possible involvement of protease inhibitor ras proteins in malignant transformation. (1988)

Based on our recent finding that human c-Ha-ras gene products (p21s) inhibit the activities of thiol proteinases, a possible new model for malignant transformation is proposed. The model involves a new concept that p21s can cause effects on the protein kinase activities of growth factor receptors by affecting down regulation of the receptors.
Molecular Layer Deposition of Nanoscale Organic Films for Nanoelectronics Applications (2014)

The development of new processes for depositing thin organic films has seen a renewed interest due to an increased demand for nanoelectronic devices. Tools for producing these devices, such as advanced lithographic patterning, often require ultrathin films with a high degree of compositional homogeneity. Molecular layer deposition (MLD) is a promising method for creating films with these qualities. By using an alternating sequence of self-saturating reactions, MLD can produce conformal films with a high degree of control over the composition and thickness. In a series of studies by our group, photoresist films were grown using MLD by incorporated acid-labile groups into a MLD-grown polyurea chain. The inclusion of photo acid generators was demonstrated both as a soaked-in additive as well as a polymer-bound reactive group. These films show potential as good photoresist materials, with some designs exhibiting sensitivities of 30 µC/cm 2 with 100 kV electron beam exposure, and a line resolution of sub-100 nm.
Iniciação à internet (2011)

A Iniciação à Internet é um texto introdutório destinado a quem se inicie no mundo da Internet. O objectivo do texto é que o leitor consiga navegar na Internet, encontrar a informação que pretende através das diversas formas disponíveis, e consiga construir conteúdo, publicá-lo e publicitá-lo, utilizando para tal os conhecimentos mínimos e rápidos. Não é dado ênfase a sites concretos, muito embora sejam sempre referenciados sites para as funcionalidades introduzidas.
Theoretical noise estimation in 3D X-ray cone-beam CT reconstruction (2010)

Many researchers have been studying on the noise properties and image quality influence on system performance for tomographic imaging in recent years. Most of the works are focused on 2D nuclear medicine imaging. Since X-ray CT dosage has been pushed to a lower level and 3D imaging has been a trend, it is necessary to study the performance of 3D X-ray CT systems. In this work, we presented a new theoretical estimation method for a critical noise property: covariance, of the classical FDK reconstructions for 3D X-ray CT. The method is easy to implement. The theory is validated by numerical MC simulation. Our results confirm that theoretical estimation of covariance and variance in CT image reconstruction match the MC result well. Hence, the propose method can exempt us from computationally expensive MC studies.
Mathematical Modeling of Sandstone Stimulation: A Critical Review of Available Models (2000)

Abstract This paper reviews previous work done on mathematical modeling of the chemical reactions between sandstone and mud acid, which is a mixture of HF and HCl acids. These models are lumped-parameter model, two-parameter model, four-parameter model, and detailed chemistry models. The models are compared with the experimental data at different flow rates. The lumped-parameter model simplifies the chemistry of the dissolution of sandstone minerals with mud acid. The two-parameter model predicts lab experiments at high flow rates only. Predictions based on the four-parameter model agreed with the experimental data over a wide range of flow rates. Detailed chemistry models have no advantage in predicting experimental data over the four-parameter model. In addition, detailed chemistry models fail to predict coreflood experiments at low acid injection flow rates.
A cooperative network at the nuclear envelope counteracts LINC-mediated forces during oogenesis in <i>C. elegans</i> (2023)

Oogenesis involves transduction of mechanical forces from the cytoskeleton to the nuclear envelope (NE). In <i>Caenorhabditis elegans</i>, oocyte nuclei lacking the single lamin protein LMN-1 are vulnerable to collapse under forces mediated through LINC (linker of nucleoskeleton and cytoskeleton) complexes. Here, we use cytological analysis and in vivo imaging to investigate the balance of forces that drive this collapse and protect oocyte nuclei. We also use a mechano-node-pore sensing device to directly measure the effect of genetic mutations on oocyte nuclear stiffness. We find that nuclear collapse is not a consequence of apoptosis. It is promoted by dynein, which induces polarization of a LINC complex composed of Sad1 and UNC-84 homology 1 (SUN-1) and ZYGote defective 12 (ZYG-12). Lamins contribute to oocyte nuclear stiffness and cooperate with other inner nuclear membrane proteins to distribute LINC complexes and protect nuclei from collapse. We speculate that a similar network may protect oocyte integrity during extended oocyte arrest in mammals.
A Robust System for Visual Pattern Recognition in Engineering Drawing Documents (2018)

In AEC (Architectural, Engineering and Constructional) domain, the architects use several types of drawing documents. These documents consist of various category of graphical objects and such objects can be classified based on their shape and curvature properties. Here, we have proposed a query enabled image searching system which can be used to locate objects in a set of documents. To achieve our goal, at-first we have identified a key point search window based on the inflection points of the contour of the object. Then, for each window we try to classify the curve segment into positive or negative class based on the curvature values. Then depending on the predicted class, we get the maxima or minima point on the contour. Now, we use these points as seed values (initial key points) to our feature detection mechanism. To extract the shape and/or curvature properties of the objects at different levels of scale and orientation, we have employed two feature extraction mechanisms. To get the local feature descriptor, we have introduced a neighborhood-based curvature extraction methodology and to consider the global shape of the object, Hu moments based shape descriptor of the object contour is computed. Finally, these two features are normalized, and their combined feature vector is used to compare and measure the similarity between the key points of two objects. We have also introduced a mechanism to identify the query object as a whole, when it consists of multiple overlapping contours for a single object. We have tested our system on a variety of AEC class of drawing documents and the results are quite encouraging. The proposed system will enable the users to locate similar objects inside a project consisting of hundreds of documents. Also, the method can be used for object hyperlinking with some alterations.
Cyberspace Chat: Post-operative Nausea and Vomiting Associated with Anesthesia During Hair Transplantation (2015)

1. John P. Cole, MD (john{at}forhair.com) 1. Alpharetta, Georgia, USA 2. Bradley R. Wolf, MD, FISHRS (wolf{at}wolfhair.com) 1. Cincinnati, Ohio, USA </br>![][1]</img> Mike Beehner began the string on the topic of post-operative nausea/vomiting: My patient today was an
Effects of Relaxin on Blood Pressure and the Release of Vasopressin and Oxytocin in Anesthetized Rats during Pregnancy and Lactation1 (1994)

The effects of porcine relaxin (pRXN) on arterial blood pressure and on the release of vasopressin (VP) and oxytocin (OT) were investigated in urethane-anesthetized rats at different stages of pregnancy and lactation. Acute i.v. pRXN (5 micrograms) caused a significant increase in systolic and diastolic blood pressure in pregnant and lactating rats. However, the pressor response was attenuated from Day 14 of pregnancy to Day 1 of lactation. The hormone had no effect on blood pressure in Day 16, Day 19, or Day 21 pregnant rats. At all stages of pregnancy and lactation, i.v. pRXN caused a significant increase in plasma VP concentrations. This response was attenuated in Day 19 and Day 21 pregnant and in Day 1 lactating rats. Intravenous pRXN also caused a significant, short-term increase in plasma OT in pregnant and lactating rats. The OT response to pRXN was attenuated on Day 16 of pregnancy, and pRXN had no effect on plasma OT in late-pregnant rats. The data in this study demonstrate that pRXN causes an increase in both arterial blood pressure and VP and OT release in anesthetized pregnant and lactating rats. However, these effects are either reduced or not observed in late-pregnant and early-lactating rats.
&lt;title&gt;Range-image segmentation, free-space determination, and position estimate for a mobile vehicle&lt;/title&gt; (1993)

Two processing methods using range data are shown to perform different navigation tasks for a mobile vehicle. The first, a low-level processing method based on mathematical morphology, computes in real time, the free space and is used for collision avoidance. A parallel between this method and polar histogram techniques is drawn. The second method, based on a hierarchical segmentation technique, can extract a multiple resolution description of the range data produced by the sensor. This segmentation is used to describe the immediate environment of the vehicle using simple geometrical primitives, refine the vehicle position estimate, and create a detailed representation of the immediate environment of the vehicle. Experimental results using the BIRIS range sensor are shown.
High-power, fiber-coupled stack arrays for pump applications (2008)

Here we present details of the design and performance of a family of compact, fiber-coupled, multi-bar, laser-diode stacks. The highest-power variant employs a pair of 6-bar stacks and a removable 400-&mu;m, 0.22 NA fiber to deliver >400 W at 50 A. The overall power conversion efficiency (PCE) near 976-nm exceeds 40% at 400 W in CW operation with an uncoated delivery fiber. The brightest variant reaches a power density near 800-kW/cm<sup>2</sup> at 976-nm through a 200-&mu;m, 0.22 NA fiber. Module variants have been built and characterized at multiple wavelengths between 780-nm and 980-nm. Applications for such modules include pumping of active fibers, pumping of rubidium vapor and direct material processing.
The immune adaptor MPYS/STING/MITA signals via multiple differentially regulated pathways (135.60) (2009)

Abstract MPYS, a.k.a. STING and MITA, is a newly described signaling adaptor that functions in both innate and adaptive immunity. MPYS transduces apoptotic death signals when aggregated on the B cell surface, but also plays an obligate role in the intracellular sensing of B-DNA and infectious agents. The basis of MPYS signal transduction is unclear. We report that MPYS signals by two distinct pathways. It associates via its juxtamembrane Box 1 and phosphotyrosine motifs with Tyk2 and STAT1, and utilizes these effectors in ISRE activation. Activation of IFNbeta occurs via MPYS association with and activation of TBK1 and IRF3, and is independent of VISA. MPYS (but not VISA) activation of IFNbeta expression is sensitive to LPS-induced TLR4-independent inhibition, but is positively cooperative with TLR signals. Thus MPYS activates multiple, uniquely regulated signaling pathways to mediate resistance to infection and regulation of adaptive immunity.
Potent Pyrimidine and Pyrrolopyrimidine Inhibitors of Testis‐Specific Serine/Threonine Kinase 2 (TSSK2) (2017)

Testis-specific serine/threonine kinase 2 (TSSK2) is an important target for reversible male contraception. A high-throughput screen of ≈17 000 compounds using a mobility shift assay identified two potent series of inhibitors having a pyrrolopyrimidine or pyrimidine core. The pyrrolopyrimidine 10 (IC<sub>50</sub> 22 nm; GSK2163632A) and the pyrimidine 17 (IC<sub>50</sub> 31 nm; ALK inhibitor 1) are the most potent TSSK2 inhibitors in these series, which contain the first sub-100 nanomolar inhibitors of any TSSK isoform reported, except for the broad kinase inhibitor staurosporine. The novel, potent pyrimidine TSSK2 inhibitor compound 19 (IC<sub>50</sub> 66 nm; 2-[[5-chloro-2-[2-methoxy-4-(1-methylpiperidin-4-yl)anilino]pyrimidin-4-yl]amino]-N-methylbenzenesulfonamide) lacks the potential for metabolic activation. Compound 19 had a potency rank order of TSSK1>TSSK2>TSSK3>TSSK6, indicating that potent dual inhibitors of TSSK1/2 can be identified, which may be required for a complete contraceptive effect. The future availability of a TSSK2 crystal structure will facilitate structure-based discovery of selective TSSK inhibitors from these pyrrolopyrimidine and pyrimidine scaffolds.
&lt;i&gt;Streptococcus thermophilus&lt;/i&gt; extends lifespan through activation of DAF-16-mediated antioxidant pathway in &lt;i&gt;Caenorhabditis elegans&lt;/i&gt; (2021)

<i>Streptococcus thermophilus</i> bacteria, which are widely used as fermented starter for dairy production, exert various beneficial health effects. Nevertheless, even though pro-longevity effects of various probiotics have been reported, no report has described <i>Streptococcus thermophilus</i> effects on longevity. This study was conducted to evaluate <i>Streptococcus thermophilus</i> effects on lifespan extension and to elucidate the <i>Streptococcus thermophilus</i>-mediated longevity mechanism using <i>Caenorhabditis elegans</i> worms as a model animal. They were fed standard food (<i>Escherichia coli</i> OP50) or <i>Streptococcus thermophilus</i> from the young adult stage. Feeding with <i>Streptococcus thermophilus</i>, compared to <i>Escherichia coli</i> OP50, to <i>Caenorhabditis elegans</i> extend the lifespan, reduced lipofuscin accumulation, and maintain vigorous locomotion. Feeding with <i>Streptococcus thermophilus</i> did not alter the worm growth curve or the offspring number, indicating that the <i>Streptococcus thermophilus</i>-mediated lifespan extension is not attributable to caloric restriction. The qRT-PCR data showed that <i>Streptococcus thermophilus</i> increased the expression of <i>daf-16</i> and some of its downstream antioxidant genes. Furthermore, the pro-longevity effects of <i>Streptococcus thermophilus</i> were decreased in loss-of-function mutant of <i>daf-16</i>. Results show that <i>Streptococcus thermophilus</i> extends the lifespan of <i>Caenorhabditis elegans</i> through DAF-16-mediated antioxidant pathway activation.