gebhart/patrepeval huggingface dataset:
Integrating Vehicle Slip and Yaw in Overarching Multi-Tiered Automated Vehicle Steering Control to Balance Path Following Accuracy, Gracefulness, and Safety (2022)

Balancing path following accuracy and error convergence with graceful motion in steering control is challenging due to the competing nature of these requirements, especially across a range of operating speeds and conditions. This paper demonstrates that an integrated multi-tiered steering controller considering the impact of slip on kinematic control, dynamic control, and steering actuator rate commands achieves accurate and graceful path following. This work is founded on multi-tiered sideslip and yaw-based models, which allow derivation of controllers considering error due to sideslip and the mapping between steering commands and graceful lateral motion. Observer based sideslip estimates are combined with heading error in the kinematic controller to provide feedforward slip compensation. Path following error is compensated by a continuous Variable Structure Controller (VSC) using speed-based path manifolds to balance graceful motion and error convergence. Resulting yaw rate commands are used by a backstepping dynamic controller to generate steering rate commands. A High Gain Observer (HGO) estimates sideslip and yaw rate for output feedback control. Stability analysis of the output feedback controller is provided, and peaking is resolved. The work focuses on lateral control alone so that the steering controller can be combined with other speed controllers. Field results provide comparisons to related approaches demonstrating gracefulness and accuracy in different complex scenarios with varied weather conditions and perturbations.
Revisiting the Design of Parallel Stream Joins on Trusted Execution Environments (2022)

The appealing properties of secure hardware solutions such as trusted execution environment (TEE) including low computational overhead, confidentiality guarantee, and reduced attack surface have prompted considerable interest in adopting them for secure stream processing applications. In this paper, we revisit the design of parallel stream join algorithms on multicore processors with TEEs. In particular, we conduct a series of profiling experiments to investigate the impact of alternative design choices to parallelize stream joins on TEE including: (1) execution approaches, (2) partitioning schemes, and (3) distributed scheduling strategies. From the profiling study, we observe three major high-performance impediments: (a) the computational overhead introduced with cryptographic primitives associated with page swapping operations, (b) the restrictive Enclave Page Cache (EPC) size that limits the supported amount of in-memory processing, and (c) the lack of vertical scalability to support the increasing workload often required for near real-time applications. Addressing these issues allowed us to design SecJoin, a more efficient parallel stream join algorithm that exploits modern scale-out architectures with TEEs rendering no trade-offs on security whilst optimizing performance. We present our model-driven parameterization of SecJoin and share our experimental results which have shown up to 4-folds of improvements in terms of throughput and latency.
Effects of elevating colonic propionate on liver fat content in overweight adults with non-alcoholic fatty liver disease: a pilot study (2015)

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Effect of seed replacement through front line demonstration of soybean, wheat & chickpea in black soils of Madhya Pradesh (2012)

An experiment was conducted under M.s. Swaminathan Research Foundation -O.S.U. - J.N. Krishi Vishwa Vidhyalaya, Jabalpur collaborative project on farmer's field at three villages of Narsinghpur block in Narsinghpur district of Madhya Pradesh during 2001–02 to 2004–05. Under this project Soybean, Wheat and Chickpea were selected for sowing the FLD's in farmers field. Total four quintals breeder seed of soybean and wheat each three and half quintals of chickpea crop were used. Due to these interventions like use of improved seed and production technoogy the percent increase of the yield over conventional farming were 53, 40, 45, 32 in soybean 38, 40, 46, 39 in wheat and 42, 43, 46, 42 in chickpea crop. There was significant growth of economic status of farmers in all three villages due to distribution and replacement of improved seed and technological methods. Therefore, present study clearly indicates the use of improved inputs with integration of chemical fertilizers with organic manures sustain higher productivity of crops.
Formal Enantioselective Michael Addition with Umpolung of Reactivity (2001)

By a sequence comprising asymmetric hydroboration, boron-zinc exchange, and transmetalation with copper, allylations, alkynylations, and allenylations of unsaturated ketals or acetals can be performed with good enantioselectivities (see scheme, (-)-IpcBH2 =(-)-isopinocampheylborane, TMS=Me3 Si). The products correspond to a formal Michael addition with inversion of polarity.
CMOS Latchup Process Features and Solutions – Bipolar and BiCMOS Technology (2007)

This chapter contains sections titled: CMOS Latchup in Bipolar and RF BiCMOS Technology Substrates – High-Resistance Substrates Subcollectors Alternative Isolation Concepts Trench Isolation (TI) Deep Trench Triple-Well and BiCMOS Processes Integration Heavily Doped Buried Layer Implant and BiCMOS Technology Summary and Closing Comments Problems References
The Effect of Intensity on 3-Dimensional Kinematics and Coordination in Front-Crawl Swimming (2015)

Swimming intensity has a significant impact on swimmers' segmental kinematics and interlimb coordination, with modifications being more evident after the point when AnT is reached. As competitive swimming events are conducted at high intensities (in which anaerobic metabolism becomes more prevalent), coaches should implement specific training series that lead swimmers to adapt their technique to the task constraints that exist in nonhomeostatic race conditions.
Exploring the photophysics and photocatalytic properties of platinum and palladium nanoparticles (2012)

Platinum and Palladium nanoparticles are important nanoscale materials for a variety of materials science and industrial applications. The presented research covers a broad spectrum of these unique nanoparticles, from their synthesis and characterization to their use in systems that examine their photophysical properties and as catalysts and photocatalysts. We developed a new synthetic method for producing well-defined platinum and palladium nanoparticles of less than 5 nm diameter. The nanoparticles are stabilized by long chain thioethers, which allow them to retain their stability in a variety of solvent environments. Stability and size control are critical to the application of these particles to experimental research in a variety of systems. After demonstrating the catalytic activity of these nanoparticles, we developed a method for linking them to magnetic cobalt ferrite nanoparticles. These linked particles were found to be highly recoverable when placed in a magnetic field, allowing for their reuse. In addition to traditional catalytic systems, platinum and palladium nanoparticles hold great potential as photocatalysts. We chose to study their use in two such systems. The first system explored involved utilizing platinum nanoparticles as charge transfer catalysts from titanium dioxide nanoparticles. We demonstrated the ability of this system for the degradation of an organic dye as well as for hydrogen production via water splitting, both under dark conditions. The final system explored involved studying the interaction between cadmium selenide quantum dots and palladium nanoparticles in solution. As a prelude to this research, we conducted an extensive study on the effects of stabilizing ligands on quantum dot fluorescence dynamics. We developed a model to define the dynamics of the dots based on changes in native ligand coverage upon sample dilution. These studies allowed us to take these effects into account before studying the interaction of the dots with palladium nanoparticles. Palladium nanoparticles were found to exhibit two distinct effects on quantum dot fluorescence in solution. At higher palladium concentrations, we observed a quenching of the quantum dot fluorescence and shortening of the lifetime, which was attributed to Fo¨rster energy transfer from the quantum dots to the nanoparticles. Low palladium concentrations exhibited opposite effects, which were attributed to enhanced absorption, similar to previously studied quantum dot -- gold nanoparticle systems. By fully studying these nanoparticles, from their synthesis and characterization to their use in various systems, we in turn developed a thorough understanding of their unique photophysical properties.
Legends to supplementary figures from Critical Role of STAT3 in IL-6–Mediated Drug Resistance in Human Neuroblastoma (2023)

&lt;p&gt;Legends to supplementary figures - PDF file 87K, Legends to supplementary figures 1 to 4&lt;/p&gt;
Reversible glycosidic switch for secure delivery of molecular nanocargos (2018)

Therapeutic drugs can leak from nanocarriers before reaching their cellular targets. Here we describe the concept of a chemical switch which responds to environmental conditions to alternate between a lipid-soluble state for efficient cargo loading and a water-soluble state for stable retention of cargos inside liposomes. A cue-responsive trigger allows release of the molecular cargo at specific cellular sites. We demonstrate the utility of a specific glycosidic switch for encapsulation of potent anticancer drugs and fluorescent compounds. Stable retention of drugs in liposomes allowed generation of high tumor/blood ratios of parental drug in tumors after enzymatic hydrolysis of the glycosidic switch in the lysosomes of cancer cells. Glycosidic switch liposomes could cure mice bearing human breast cancer tumors without significant weight loss. The chemical switch represents a general method to load and retain cargos inside liposomes, thereby offering new perspectives in engineering safe and effective liposomes for therapy and imaging.
ChemInform Abstract: Analysis of Active Site Distribution in ZSM‐5 Crystals by IR Microscopy. (1994)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Introduction to the Issue on Cooperative Signal Processing for Heterogeneous and Multi-Task Wireless Sensor Networks (2017)

The papers in this special section focus on the deployment of cooperative signal process for use in heterogeneous and multi-tasking wireless sensor networks. These devices operate on their own to solve a single or multiple signal processing tasks. In a wireless sensor network (WSN), devices that observe the same phenomenon collaborate to exploit spatial diversity and achieve an improved performance. However, traditional WSNs typically assume a homogeneous setting, in which each device is the same, and in which all the nodes cooperate to solve a single network-wide signal processing task.
Probing carbon isotope effects on the Raman spectra of graphene with different<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:mrow><mml:mmultiscripts><mml:mi mathvariant="normal">C</mml:mi><mml:mprescripts/><mml:none/><mml:mrow><mml:mn>13</mml:mn></mml:mrow></mml:mmultiscripts></mml:mrow></mml:math>concentrations (2015)

A resonance Raman study of graphene samples with different $^{13}\mathrm{C}$ isotopic concentrations and using different laser excitation energies is presented. The main Raman peaks ($D, G, {G}^{*}$, and $2D$) of graphene were measured and the dependence of their frequencies on the isotope atomic mass follows a simple harmonic oscillator relation. The ${G}^{*}$ and $2D$ double-resonance peak positions were measured as a function of the laser energy, and we observed that the slopes of the laser energy dependence are the same independently of isotope concentration. This result shows that isotopic substitution does not alter the electron and phonon dispersions near the $K$ point of the graphene Brillouin zone. From the linewidth of $G$ and $2D$ Raman peaks, we have also obtained a dependence of the phonon lifetime on the $^{13}\mathrm{C}$ isotope concentration.
25aB6-12 トランズモン型超伝導量子ビットの時間分解測定(量子エレクトロニクス(量子コンピューター・デコヒーレンス),領域1(原子・分子,量子エレクトロニクス,放射線物理)) (2013)

Combined delivery of specific interventions or services may yield greater improvements in child outcomes across different developmental domains. It is recommended that multiple support avenues in combination like improving food security and safe communities, as well as social protection grants, should be provided for vulnerable children to maximize the impact.
The Importance and Challenges of Identifying SARS-CoV-2 Reinfections (2020)

Reports of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) reinfection have raised important questions about the strength and durability of the immune response to primary infection, which are key factors in predicting the course of the pandemic. Identifying reinfection requires detecting the virus at two different time points and using viral genomic data to distinguish reinfection from persistent viral carriage. This process is hindered by challenges of logistics and capacity, such as banking samples from primary infection and performing viral genome sequencing. These challenges may help to explain why very few cases have been described to date. In addition, reinfection may be a rare phenomenon, but detailed prospective studies are needed to rigorously assess its frequency. To provide context for future investigations of SARS-CoV-2 reinfection, we review 16 cases that have been published to date or are available in preprint. Reinfection occurred across demographic spectra and in patients whose initial infections were both asymptomatic/mild and moderate/severe. For cases in which severity could be compared between episodes, half of reinfections were less severe, raising the possibility of partial immune protection. Although many patients had a positive total immunoglobulin or IgG result at the time of reinfection, very little examination of their immune response was performed. Further work is needed to elucidate the frequency, determinants, and consequences of SARS-CoV-2 reinfection. Establishing the necessary frameworks for surveillance and investigation will rely heavily on clinical laboratories and clinical investigators, and we propose several considerations to guide the medical community in identifying and characterizing SARS-CoV-2 reinfections.
Microstructure of lower bainite formed at large undercoolings below bainite start temperature (1996)

Metallographic observations of steel samples transformed isothermally to lower bainite at temperatures well below the bainite start temperature have revealed that it is possible for separately nucleated platelets to coalesce during prolonged growth. The circumstances conducive to the coalescence process are discussed, and a mechanism is proposed to explain why a bimodal size distribution of plate thickness is sometimes observed for lower bainite and martensite.MST/3370
High density electrical feedthrough fabricated by deep reactive ion etching of Pyrex glass (2002)

This paper reports a new fabrication technology of Pyrex glass with a fine pitch electrical feedthrough. Small through holes (40-60 /spl mu/m in diameter) in Pyrex glass plate have been fabricated using deep reactive ion etching in sulfur hexafluoride (SF/sub 6/) plasma. By filling the through holes with electroplated metal, the fine pitch electrical feedthrough in Pyrex glass plate becomes enable technology. Pyrex glass can be anodically bonded with silicon. Thus, our technology will be widely used for high density electrical feedthrough to the backside of a plate. The applications of the technology to micro probe array used for high density data storage and packaged devices are expected.
Preparation of BST thin films on Pt electrode on Si wafer with down-flow LSMCVD reactor (1996)

Abstract A novel type of down-flow LSMCVD (Liquid Source Mist CVD) reactor was developed to prepare a high dielectric BST thin film on Pt electrode on Si wafer. Barium acetate [Ba (OOCCH3)2], strontium acetate [Sr (OOCCH3)2], and titanium isoproxide [Ti (OC3H7 i )4] were used as metal sources. Metal sources were dissolved in acetic acid, 1-butanol, or 2-methoxyethanol. BST [Ba/(Ba + Sr) = 0.7] film annealed on Pt/Ti/SiO2/Si above 650°C was polycrystalline. BST film has a (110) preferred orientation with increasing temperature. Surface roughness of BST film and grain size increased with increasing temperature. The metal-oxygen bond was formed at 650°C as shown in the spectra of FTIR. The depth profiles of elements of BST thin films indicated a uniform composition throughout the film. BST films annealed at 750°C showed a dielectric constant and a tanδ of 390 (thickness: 150 nm) and 0.06 at a frequency of 100 kHz, respectively. The behavior of capacitance of the BST film with bias voltage showed paraelectric property. BST film annealed at 750°C had the leakage current density of 3.2 (μA/cm2) at a bias voltage of 2V.
Synthesis of Poly(&lt;em&gt;N&lt;/em&gt;-isopropylacrylamide) Janus Microhydrogels for Anisotropic Thermo-responsiveness and Organophilic/Hydrophilic Loading Capability (2016)

Janus microparticles are compartmentalized particles with differing molecular structures and/or functionality on each of their two sides. Because of this unique property, Janus microparticles have been recognized as a new class of materials, thereby attracting a great deal of attention from various research fields. The versatility of these microparticles has been exemplified through their uses as building blocks for self-assembly, electrically responsive actuators, emulsifiers for painting and cosmetics, and carriers for drug delivery. This study introduces a detailed protocol that explicitly describes a synthetic method for designing novel Janus microhydrogels composed of a single base material, poly(N-isopropylacrylamide) (PNIPAAm). Janus microdroplets are firstly generated via a hydrodynamic focusing microfluidic device (HFMD) based on the separation of a supersaturated aqueous NIPAAm monomer solution and subsequently polymerized through exposure to UV irradiation. The resulting Janus microhydrogels were found to be entirely composed of the same base material, featured an easily identifiable compartmentalized morphology, and exhibited anisotropic thermo-responsiveness and organophilic/hydrophilic loading capability. We believe that the proposed method introduces a novel hydrogel platform with the potential for advanced synthesis of multi-functional Janus microhydrogels.
Structural Basis for the Brilliant Colors of the Sapphirinid Copepods (2015)

Males of sapphirinid copepods use regularly alternating layers of hexagonal-shaped guanine crystals and cytoplasm to produce spectacular structural colors. In order to understand the mechanism by which the different colors are produced, we measured the reflectance of live individuals and then characterized the organization of the crystals and the cytoplasm layers in the same individuals using cryo-SEM. On the basis of these measurements, we calculated the expected reflectance spectra and found that they are strikingly similar to the measured ones. We show that variations in the cytoplasm layer thickness are mainly responsible for the different reflected colors and also that the copepod color strongly depends on the angular orientation relative to the incident light, which can account for its appearance and disappearance during spiral swimming in the natural habitat.
Development of On-Line Solid-Phase Extraction-Liquid Chromatography Coupled with Tandem Mass Spectrometry Method to Quantify Pharmaceutical, Glucuronide Conjugates and Metabolites in Water (2016)

International audience
Introns are cis effectors of the nonsense-codon-mediated reduction in nuclear mRNA abundance. (1994)

The translation of human triosephosphate isomerase (TPI) mRNA normally terminates at codon 249 within exon 7, the final exon. Frameshift and nonsense mutations of the type that cause translation to terminate prematurely at or upstream of codon 189 within exon 6 reduce the level of nuclear TPI mRNA to 20 to 30% of normal by a mechanism that is not a function of the distance of the nonsense codon from either the translation initiation or termination codon. In contrast, frameshift and nonsense mutations of another type that cause translation to terminate prematurely at or downstream of codon 208, also within exon 6, have no effect on the level of nuclear TPI mRNA. In this work, quantitations of RNA that derived from TPI alleles in which nonsense codons had been generated between codons 189 and 208 revealed that the boundary between the two types of nonsense codons resides between codons 192 and 195. The analysis of TPI gene insertions and deletions indicated that the positional feature differentiating the two types of nonsense codons is the distance of the nonsense codon upstream of intron 6. For example, the movement of intron 6 to a position downstream of its normal location resulted in a concomitant downstream movement of the boundary between the two types of nonsense codons. The analysis of intron 6 mutations indicated that the intron 6 effect is stipulated by the 88 nucleotides residing between the 5' and 3' splice sites. Since the deletion of intron 6 resulted in only partial abrogation of the nonsense codon-mediated reduction in the level of TPI mRNA, other sequences within TPI pre-mRNA must function in the effect. One of these sequences may be intron 2, since the deletion of intron 2 also resulted in partial abrogation of the effect. In experiments that switched introns 2 and 6, the replacement of intron 6 with intron 2 was of no consequence to the effect of a nonsense codon within either exon 1 or exon 6. In contrast, the replacement of intron 2 with intron 6 was inconsequential to the effect of a nonsense codon in exon 6 but resulted in partial abrogation of a nonsense codon in exon 1.
An Analysis of Rivet Die Design in Electromagnetic Riveting (1988)

This paper presents the findings of a numerical and experimental study of the quality of 7050-T73 aluminum rivets formed by an extremely fast electromagnetic riveting process. It is found that without careful design of the rivet forming die large strains are produced which cause crack formation in the rivet heads. By the use of finite element and experimental techniques, it is shown that control of the radial component of the flow of material in the rivet head is essential in avoiding crack formation. A rivet die design which is effective in producing high quality, crack free, rivets is proposed.
Supplementary Figure Legends 1-5 from Akt1 and Akt2 Play Distinct Roles in the Initiation and Metastatic Phases of Mammary Tumor Progression (2023)

Supplementary Figure Legends 1-5 from Akt1 and Akt2 Play Distinct Roles in the Initiation and Metastatic Phases of Mammary Tumor Progression