gebhart/patrepeval huggingface dataset:
Ensemble Machine-Learning Models for Accurate Prediction of Solar Irradiation in Bangladesh (2023)

Improved irradiance forecasting ensures precise solar power generation forecasts, resulting in smoother operation of the distribution grid. Empirical models are used to estimate irradiation using a wide range of data and specific national or regional parameters. In contrast, algorithms based on Artificial Intelligence (AI) are becoming increasingly popular and effective for estimating solar irradiance. Although there has been significant development in this area elsewhere, employing an AI model to investigate irradiance in Bangladesh is limited. This research forecasts solar radiation in Bangladesh using ensemble machine-learning models. The meteorological data collected from 32 stations contain maximum temperature, minimum temperature, total rain, humidity, sunshine, wind speed, cloud coverage, and irradiance. Ensemble machine-learning algorithms including Adaboost regression (ABR), gradient-boosting regression (GBR), random forest regression (RFR), and bagging regression (BR) are developed to predict solar irradiance. With the default parameters, the GBR provides the best performance as it has the lowest standard deviation of errors. Then, the important hyperparameters of the GRB are tuned with the grid-search algorithms to further improve the prediction accuracy. On the testing dataset, the optimized GBR has the highest coefficient of determination (R2) performance, with a value of 0.9995. The same approach also has the lowest root mean squared error (0.0007), mean absolute percentage error (0.0052), and mean squared logarithmic error (0.0001), implying superior performance. The absolute error of the prediction lies within a narrow range, indicating good performance. Overall, ensemble machine-learning models are an effective method for forecasting irradiance in Bangladesh. They can attain high accuracy and robustness and give significant information for the assessment of solar energy resources.
Chemoselective Oxidation of Secondary Alcohols Using a Ruthenium Phenylindenyl Complex (2013)

A straightforward catalytic alcohol oxidation procedure using the recently reported complex [RuCl(PPh3)2(3-phenylindenyl)] (1) with KHMDS as cocatalyst, in acetone as the oxidant, is reported. Complex 1 shows remarkable chemoselectivity in oxidizing secondary alcohols to ketones.
Application of a Bimetallic Treatment System (BTS) for PCB Removal from Older Structures on DoD Facilities (2010)

Abstract : This project demonstrated the efficacy of a Bimetallic Treatment System (BTS) to remove and rapidly degrade polychlorinated biphenyls (PCB) found in structural coatings. The BTS technology, which consists of elemental or zero-valent magnesium (ZVM) coated with a small amount of palladium in a solvent solution capable of hydrogen donation, has two functions: (1) to extract PCBs from weathered, decades-old coating material such as paint; and (2) to degrade the extracted PCBs. Results are presented for pre-demonstration laboratory testing and field testing conducted at: (1) the Vertical Integration Building (VIB), Cape Canaveral, Florida; and (2) Badger Army Ammunition Plant, Wisconsin. Variables evaluated in the demonstration include the substrates on which the PCB coatings have been applied (i.e., metal, concrete or wood); age of the coatings; adhesion, appearance: and substrate condition on removal of the BTS and PCB coating. Field testing included applying the treatment substrate to various surfaces with coatings containing PCBs and evaluating the removal of the PCBs from the surface and destruction of the PCB by the treatment substrate. The demonstration goal was to reach PCB concentrations below the Toxic Substances Control Act limit of 50 parts per million (ppm) in the paint on all structures tested.
COHO - Utilizing Waste Heat and Carbon Dioxide at Power Plants for Water Treatment (2017)

The COHO is a breakthrough water purification system that can concentrate challenging feed waters using carbon dioxide and low-grade heat. For this project, we studied feeds in a lab-scale system to simulate COHO’s potential to operate at coal- powered power plants. COHO proved successful at concentrating the highly scaling and challenging wastewaters derived from a power plant’s cooling towers and flue gas desulfurization units. We also found that COHO was successful at scrubbing carbon dioxide from flue gas mixtures. Thermal regeneration of the switchable polarity solvent forward osmosis draw solution ended up requiring higher temperatures than initially anticipated, but we also found that the draw solution could be polished via reverse osmosis. A techno-economic analysis indicates that installation of a COHO at a power plant for wastewater treatment would result in significant savings.
Relaxation of capillary-gravity waves due to contact line nonlinearity: A projection method (2021)

We present a physics-inspired mathematical model based on successive linear eigenmode projections to solve the relaxation of small-amplitude and two-dimensional viscous capillary-gravity waves with a phenomenological nonlinear contact line model. We show that each projection eventually induces a rapid loss of total energy in the liquid motion and contributes to its nonlinear damping.
Exploration of a virtual environment (2015)

This paper proposes an experimental protocol that aims to evaluate in a strictly comparable context tactile and tangible modalities for a virtual environment exploration on tablet. We propose four modalities: tactile interaction with sticks, classic tactile interaction, tangible interaction with a 1:2.5 scale factor and tangible interaction with a 1:5 scale factor. We hypothesize that the tangible interactions will provide users a better spatial representation of the virtual environment, with however, a difference depending on the scale factor. Moreover we interest on the subjective evaluation (usability and acceptability) of these modalities.
Predicting the Mechanical Properties of Organic Semiconductors Using Coarse-Grained Molecular Dynamics Simulations (2016)

The ability to predict the mechanical properties of organic semiconductors is of critical importance for roll-to-roll production and thermomechanical reliability of organic electronic devices. Here, we describe the use of coarse-grained molecular dynamics simulations to predict the density, tensile modulus, Poisson ratio, and glass transition temperature for poly(3-hexylthiophene) (P3HT) and its blend with C60. In particular, we show that the resolution of the coarse-grained model has a strong effect on the predicted properties. We find that a one-site model, in which each 3-hexylthiophene unit is represented by one coarse-grained bead, predicts significantly inaccurate values of density and tensile modulus. In contrast, a three-site model, with one coarse-grained bead for the thiophene ring and two for the hexyl chain, predicts values that are very close to experimental measurements (density = 0.955 g cm–3, tensile modulus = 1.23 GPa, Poisson ratio = 0.35, and glass transition temperature = 290 K). The model also correctly predicts the strain-induced alignment of chains as well as the vitrification of P3HT by C60 and the corresponding increase in the tensile modulus (tensile modulus = 1.92 GPa, glass transition temperature = 310 K). We also observe a decrease in the radius of gyration and the density of entanglements of the P3HT chains with the addition C60 which may contribute to the experimentally noted brittleness of the composite material. Although extension of the model to poly(3-alkylthiophenes) (P3ATs) containing side chains longer than hexyl groups—nonyl (N) and dodecyl (DD) groups—correctly predicts the trend of decreasing modulus with increasing length of the side chain measured experimentally, obtaining absolute agreement for P3NT and P3DDT could not be accomplished by a straightforward extension of the three-site coarse-grained model, indicating limited transferability of such models. Nevertheless, the accurate values obtained for P3HT and P3HT:C60 blends suggest that coarse graining is a valuable approach for predicting the thermomechanical properties of organic semiconductors of similar or more complex architectures.
Notch Signaling in Development, Tissue Homeostasis, and Disease (2017)

Notch signaling is an evolutionarily highly conserved signaling mechanism, but in contrast to signaling pathways such as Wnt, Sonic Hedgehog, and BMP/TGF-β, Notch signaling occurs via cell-cell communication, where transmembrane ligands on one cell activate transmembrane receptors on a juxtaposed cell. Originally discovered through mutations in Drosophila more than 100 yr ago, and with the first Notch gene cloned more than 30 yr ago, we are still gaining new insights into the broad effects of Notch signaling in organisms across the metazoan spectrum and its requirement for normal development of most organs in the body. In this review, we provide an overview of the Notch signaling mechanism at the molecular level and discuss how the pathway, which is architecturally quite simple, is able to engage in the control of cell fates in a broad variety of cell types. We discuss the current understanding of how Notch signaling can become derailed, either by direct mutations or by aberrant regulation, and the expanding spectrum of diseases and cancers that is a consequence of Notch dysregulation. Finally, we explore the emerging field of Notch in the control of tissue homeostasis, with examples from skin, liver, lung, intestine, and the vasculature.
CEBPA-dependent HK3 and KLF5 expression in primary AML and during AML differentiation (2014)

The basic leucine zipper transcription factor CCAAT/enhancer binding protein alpha (CEBPA) codes for a critical regulator during neutrophil differentiation. Aberrant expression or function of this protein contributes to the development of acute myeloid leukemia (AML). In this study, we identified two novel unrelated CEBPA target genes, the glycolytic enzyme hexokinase 3 (HK3) and the krüppel-like factor 5 (KLF5) transcription factor, by comparing gene profiles in two cohorts of CEBPA wild-type and mutant AML patients. In addition, we found CEBPA-dependent activation of HK3 and KLF5 transcription during all-trans retinoic acid (ATRA) mediated neutrophil differentiation of acute promyelocytic leukemia (APL) cells. Moreover, we observed direct regulation of HK3 by CEBPA, whereas our data suggest an indirect regulation of KLF5 by this transcription factor. Altogether, our data provide an explanation for low HK3 and KLF5 expression in particular AML subtype and establish these genes as novel CEBPA targets during neutrophil differentiation.
Root-Knot Nematodes Induce Cell Cycle Check Point Activation During Parasitism on Plant Hosts (2019)

International audience
Be your own cameraman (2014)

High-resolution panoramic video with a wide field-of-view is popular in many contexts. However, in many examples, like surveillance and sports, it is often desirable to zoom and pan into the generated video. A challenge in this respect is real-time support, but in this demo, we present an end-to-end real-time panorama system with interactive zoom and panning. Our system installed at Alfheim stadium, a Norwegian premier league soccer team, generates a cylindrical panorama from five 2K cameras live where the perspective is corrected in real-time when presented to the client. This gives a better and more natural zoom compared to existing systems using perspective panoramas and zoom operations using plain crop. Our experimental results indicate that virtual views can be generated far below the frame-rate threshold, i.e., on a GPU, the processing requirement per frame is about 10 milliseconds.
Mechanism of Formation of the Major Estradiol Product Ions Following Collisional Activation of the Molecular Anion in a Tandem Quadrupole Mass Spectrometer (2013)

The importance of the mass spectral product ion structure is highlighted in quantitative assays, which typically use multiple reaction monitoring (MRM), and in the discovery of novel metabolites. Estradiol is an important sex steroid whose quantitation and metabolite identification using tandem mass spectrometry has been widely employed in numerous clinical studies. Negative electrospray ionization tandem mass spectrometry of estradiol (E2) results in several product ions, including the abundant m/z 183 and 169. Although m/z 183 is one of the most abundant product ions used in many quantitative assays, the structure of m/z 183 has not been rigorously examined. We suggest a structure for m/z 183 and a mechanism of formation consistent with collision induced dissociation (CID) of E2 and several stable isotopes ([D4]-E2, [(13)C6]-E2, and [D1]-E2). An additional product ion from E2, namely m/z 169, has also been examined. MS(3) experiments indicated that both m/z 183 and m/z 169 originate from only E2 [M - H](-) m/z 271. These ions, m/z 183 and m/z 169, were also present in the collision induced decomposition mass spectra of other prominent estrogens, estrone (E1) and estriol (E3), indicating that these two product ions could be used to elucidate the estrogenic origin of novel metabolites. We propose two fragmentation schemes to explain the CID data and suggest a structure of m/z 183 and m/z 169 consistent with several isotopic variants and high resolution mass spectrometric measurements.
The apoptotic effect of hesperetin on human cervical cancer cells is mediated through cell cycle arrest, death receptor, and mitochondrial pathways (2012)

Hesperetin, a flavonoid from citrus fruits, has several bioactivities such as anti-inflammatory, antihypertensive, antiatherogenic effects. However, studies elucidating the role and the mechanism(s) of action of hesperetin in cervical cancer are sparse. In this study, we investigated the mechanism of the antiproliferative and apoptotic actions exerted by hesperetin on human cervical cancer SiHa cells. The viability of SiHa cells was evaluated using the MTT assay, apoptosis by acridine orange/ethidium bromide, propidium iodide, TUNEL assay, and Annexin V-Cy3, cell cycle distribution and mitochondrial transmembrane potential using flow cytometry, and apoptotic marker genes using quantitative real-time PCR. The treatment of SiHa cells with hesperetin (IC50, 650 μm) showed a marked concentration- and time-dependent inhibition of proliferation and induced the G2/M phase in a dose-dependent manner after 24 h. There was an attenuation of mitochondrial membrane potential with increased expression of caspase-3, caspase-8, caspase-9, p53, Bax, and Fas death receptor and its adaptor protein Fas-associated death domain-containing protein (FADD), indicating the participation of both death receptor- and mitochondria-related mechanisms. Furthermore, hesperetin-induced apoptosis was confirmed by TUNEL and Annexin V-Cy3. This study shows that hesperetin exhibits a potential anticancer activity against human cervical cancer cell lines in vitro through the reduction in cell viability and the induction of apoptosis. Altogether, these data sustain our contention that hesperetin has anticancer properties and merits further investigation as a potential therapeutic agent.
Agr Quorum Sensing influences the Wood-Ljungdahl pathway in Clostridium autoethanogenum (2022)

Acetogenic bacteria are capable of fermenting CO<sub>2</sub> and carbon monoxide containing waste-gases into a range of platform chemicals and fuels. Despite major advances in genetic engineering and improving these biocatalysts, several important physiological functions remain elusive. Among these is quorum sensing, a bacterial communication mechanism known to coordinate gene expression in response to cell population density. Two putative agr systems have been identified in the genome of Clostridium autoethanogenum suggesting bacterial communication via autoinducing signal molecules. Signal molecule-encoding agrD1 and agrD2 genes were targeted for in-frame deletion. During heterotrophic growth on fructose as a carbon and energy source, single deletions of either gene did not produce an observable phenotype. However, when both genes were simultaneously inactivated, final product concentrations in the double mutant shifted to a 1.5:1 ratio of ethanol:acetate, compared to a 0.2:1 ratio observed in the wild type control, making ethanol the dominant fermentation product. Moreover, CO<sub>2</sub> re-assimilation was also notably reduced in both hetero- and autotrophic growth conditions. These findings were supported through comparative proteomics, which showed lower expression of carbon monoxide dehydrogenase, formate dehydrogenase A and hydrogenases in the ∆agrD1∆agrD2 double mutant, but higher levels of putative alcohol and aldehyde dehydrogenases and bacterial micro-compartment proteins. These findings suggest that Agr quorum sensing, and by inference, cell density play a role in carbon resource management and use of the Wood-Ljungdahl pathway as an electron sink.
Design of S/X-Band Dual-Loop Shared-Aperture 2×2 Array Antenna (2022)

This article proposes the S/X band dual-loop shared-aperture 2 × 2 array antenna, which is constructed using a unit-cell having one Sband element stacked on 3 × 3 X-band elements. The unit-cell employs a coupled-fed dual-loop structure with a direct-feed pin on the upper loop to obtain the broadband matching characteristics and low manufacturing error. This radar configuration has the advantages of easy installation and low cost. In addition, the thin loop structure of the upper layer S-band element is optimized so that the S-band element has electromagnetic (EM) transparent characteristics in the X-band. The extended via cavity wall is also applied outside the nine Xband elements to block the mutual coupling effect among the X-band elements. To confirm the feasibility of the proposed array antenna, the beamforming performance and active reflection coefficient (ARC) characteristics of the fabricated array are examined in the S/X band.
Upgrading gasoline to high octane numbers using a zeolite-like metal–organic framework molecular sieve with <b>ana</b>-topology (2018)

Separation of paraffin isomers is of great importance in the refining industry because of their potential applications for energy efficiency, as reflected by their associated Research Octane Number (RON) values. Here, we report the synthesis of the first zeolite-like metal-organic framework (ZMOF) with ana topology that displays helicoidally/cylindrically-shaped channels with a pore-aperture size of ca. 3.8 × 6.2 Å. Markedly, such structural features offer potential for the selective separation of linear, and mono- and dibranched paraffins. Largely due to its tuned pore size and the presence of ions in the channels, ana-ZMOF possesses an excellent uniform charge density that allows the kinetic separation of n-pentane versus iso-pentane and n-butane vs. iso-butane, as well as the molecular exclusion of 2,2,4-trimethyl pentane.
A 0.05-mm<sup>2</sup> 2.91-nJ/Decision Keyword-Spotting (KWS) Chip Featuring an Always-Retention 5T-SRAM in 28-nm CMOS (2023)

This article reports a keyword-spotting (KWS) chip for voice-controlled devices. It features a number of techniques to enhance the performance, area, and power efficiencies: 1) a fast-sampling convolutional neural network (FS-CNN) that eliminates the power-hungry feature extractors and reduces the decision latency; 2) an always-retention 5T-SRAM that features word-voltage switches to reduce the leakage power and single bitline (BL) operation to halve the SRAM read power compared to the typical 6T-SRAM; and 3) a high-resolution sparsity-aware computing (HR-SAC) unit that enhances the precision and output swing of the multiply–accumulate (MAC) computation. Benchmarking with the state-of-the-art, our KWS chip prototyped in 28-nm CMOS scores a <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex-math notation="LaTeX">$&gt;$ </tex-math></inline-formula> 90% accuracy for the 11-class Google speech command dataset (GSCD) at 2.91 <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex-math notation="LaTeX">$\mu \text{W}$ </tex-math></inline-formula> , which corresponds to a 2.91-nJ energy/decision. The achieved latency is 2 ms/decision, and the core area is 0.05 <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex-math notation="LaTeX">${\mathrm{ mm}}^{2}$ </tex-math></inline-formula> , including the full KWS model.
Diffuse coplanar surface barrier discharge for treatments ofsurfaces (2012)

One of plasma sources operating at normal pressure is Diffuse
Coplanar Surface Barrier Discharge (DCSBD). The discharge can
modify many surfaces. The cleaning effect was observed on glass
and ITO and the modifications on polymers for example PMMA and
PEN. The water contact angle on surfaces was very significantly
reduced and the they were reasonable stable for applications.
Supplementary Figure 2 from Uracil–DNA Glycosylase Expression Determines Human Lung Cancer Cell Sensitivity to Pemetrexed (2023)

&lt;p&gt;PDF file - 575K, Cross resistance of pemetrexed resistant subline to other DNA damaging agents.&lt;/p&gt;
Stem cells and lung regeneration (2020)

The ability to replace defective cells in an airway with cells that can engraft, integrate, and restore a functional epithelium could potentially cure a number of lung diseases. Progress toward the development of strategies to regenerate the adult lung by either in vivo or ex vivo targeting of endogenous stem cells or pluripotent stem cell derivatives is limited by our fundamental lack of understanding of the mechanisms controlling human lung development, the precise identity and function of human lung stem and progenitor cell types, and the genetic and epigenetic control of human lung fate. In this review, we intend to discuss the known stem/progenitor cell populations, their relative differences between rodents and humans, their roles in chronic lung disease, and their therapeutic prospects. Additionally, we highlight the recent breakthroughs that have increased our understanding of these cell types. These advancements include novel lineage-traced animal models and single-cell RNA sequencing of human airway cells, which have provided critical information on the stem cell subtypes, transition states, identifying cell markers, and intricate pathways that commit a stem cell to differentiate or to maintain plasticity. As our capacity to model the human lung evolves, so will our understanding of lung regeneration and our ability to target endogenous stem cells as a therapeutic approach for lung disease.
Effects of chemical composition and test conditions on the dynamic tensile response of Zr-based metallic glasses (2017)

The effects of impact velocity and temperature on the dynamic mechanical behavior of two bulk metallic (BMG) alloys with slightly different elemental compositions (Zr55Cu30Ni5Al30 and Zr46Cu38Ag8Al38) have been investigated. Bullet-shaped samples were accelerated by a gas gun to speeds in the 400∼600m/s range and tested at both room temperature and 250°C. The samples impacted steel extrusion dies which subjected the bullets to high strains at relatively high strain-rates. The extruded fragments were subsequently soft recovered by using low density foams and examined by means of optical/scanning electron microscopy and differential scanning calorimetry. It was found that shear banding was the dictating mechanism responsible for the fracture of all BMGs. At room temperature, the Zr55Cu30Ni5Al30 alloy exhibited a higher resistance to fragmentation than the Zr46Cu38Ag8Al38 alloy. At 250°C, significant melting was observed in the recovered fragments of both alloys, which indicates that the BMG glassy structure undergoes a melting process and deformation likely occurs homogeneously.