gebhart/patrepeval huggingface dataset:
Band engineered tunnel oxides for improved TANOS-type flash program/erase with good retention and 100K cycle endurance (2009)

We demonstrate for the first time improved program, erase, and endurance for charge trap flash TaN-Al <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> O <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sub> -Si <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sub> N <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">4</sub> -ldquoTunnel-oxide (TO)rdquo-Si MOSFETs through band engineered tunnel oxides (BETO). Several high-K dielectrics (HfO <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> , HfSiO, Al <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> O <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sub> , Si <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sub> N <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">4</sub> ) and tunnel stack sequences (SiO <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> -high-k, SiO <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> -high-k-SiO <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> ) are compared. New results are as follows: SiO <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> /Al <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> O <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sub> (OA) BE-TO and SiO <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> /Si <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sub> N <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">4</sub> /SiO <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> (ONO) BE-TO DeltaVth windows improve >300% vs. standard SiO <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> -TO. Both OA and ONO stacks endure P/E cycles to at least 100 K cycles maintaining a window >4V. Results are consistent with a model based on high-k conduction/valence band offsets. Increased erase efficiency for BE-TO enables improved endurance without sacrificing P/E window due to lower P/E voltage stressing. These large, enduring windows are favorable for multi-level cell application and may extend TANOS flash beyond the 20 nm node.
Multislice input for 2D and 3D residual convolutional neural network noise reduction in CT (2023)

We conclude the that multislice input is an effective strategy for improving performance for 2D deep CNN denoising models. The pure 3D CNN model tends to have a better performance than the other models in terms of continuity across axial slices, but the difference was not significant compared with the 2D CNN model with the same number of slices as the input.
p21<sup>ras</sup> contributes to HIV‐1 activation in T‐cells (1992)

Activation of T-cells infected by HIV-1 results in activation of long terminal repeat (LTR)-dependent viral transcription and ultimately the production of infectious virus. Although full T-cell activation requires a complex series of intracellular signals, including protein kinase C activation, calcium mobilisation, and less-well defined lymphokine-induced signals, the HIV-1 LTR can be activated by subsets of these signals. We have studied the interaction of these signals in the human lymphoma line, Jurkat, in activation of the HIV-1 LTR. The HIV promoter was induced by IL-1 and phorbol ester activation of PKC but not by a calcium ionophore. The constitutively active form of Ha-ras could replace phorbol ester stimulation of the HIV promoter and of a synthetic promoter containing NF kappa B binding sites.
Service Composition for Mobile Personal Networks (2006)

Personalised networks (PN) introduce new mobility management challenges since individual devices participating in a PN may exhibit different mobility behaviour relative to one another and to human users. Mobility events may result in devices either leaving or joining the PN. In this paper we propose that PN mobility be managed by redirecting ongoing application data streams between endpoint devices in the PN. We describe a scheme to facilitate application level inter-device mobility by extending the PN to include composed network based adaptation services that adapt and reroute ongoing data streams to new endpoint devices. In order to cope with device heterogeneity and mobility, services are composed on demand and adapted in response to changes in the availability of endpoint devices. We analyse simulation results which show that our approach enables enhanced mobility handling over a range of conditions
Inorganic–Organic Nanocomposite Assembly Using Collagen as a Template and Sodium Tripolyphosphate as a Biomimetic Analog of Matrix Phosphoprotein (2011)

Nanocomposites created with polycarboxylic acid alone as a stabilization agent for prenucleation clusters-derived amorphous calcium phosphate exhibit non-periodic apatite deposition. In the present study, we report the use of inorganic polyphosphate as a biomimetic analog of matrix phosphoprotein for directing polyacrylic acid-stabilized amorphous nanoprecursor phases to assemble into periodic apatite-collagen nanocomposites. The sorption and desorption characteristics of sodium tripolyphosphate to type I collagen was examined. Periodic nanocomposite assembly with collagen as a template was demonstrated with TEM and SEM using a Portland cement-based resin composite and a phosphate-containing simulated body fluid. Apatite was detected within the collagen at 24 hours and became more distinct at 48 hours, with prenucleation clusters attaching to the collagen fibril surface during the initial infiltration stage. Apatite-collagen nanocomposites at 72 hours were heavily mineralized with periodically-arranged intrafibrillar apatite platelets. Defect-containing nanocomposites caused by desorption of TPP from collagen fibrils were observed in regions lacking the inorganic phase.
Groups Übergangsmetall-substituierte VB-Elementsysteme, 12 [1] Ein- und zweikernige Übergangsmetallkomplexe mit Dihalogenarseneinheiten / Transition Metal Substituted VB Element Systems, 12 [1] Mono-and Dinuclear Transition Metal Complexes with Dihalogenarsenic (1978)

The reaction of ASCl 3 with the transition metal anions [η 5 -C 5 H 5 (CO) 3 M] ⊖ (M = Cr, Mo, W) yields the arsenic transition metal complexes η 5 -C 5 H 5 (CO) 3 M-AsCl 2 , which readily form trans-η 5 -C 5 H 5 (CO) 2 LM-AsCl 2 in the presence of phosphorus donors [L = P(OCH 3 ) 3 , P(CH3)2C 6 H 5 ]. Addition of M(CO) 5 -groups on the trivalent arsenic occurs with THF · M′(CO) 5 (M′ = Cr, Mo) leading to the arsenic bridged dinuclear complexes η 5 -C 5 H 5 (CO) 3 Cr-AsCl 2 -M′(CO) 5. Controlled Cl/F-exchange at the bridged species can be achieved by use of AgBF 4 .
The risk of lymphoma may be increased by about fourfold in patients with inflammatory bowel disease treated with thiopurines. The increased risk could be a result of the medications, the severity of the underlying disease, or a combination of the two (2005)

T he benefits of the thiopurines, azathioprine (AZA), and 6-mercap- topurine (6-MP) in maintaining remission and corticosteroid sparing in inflammatory bowel disease (IBD) are beyond doubt. However, adverse events as well as benefits should always be considered when the effectiveness of any treatment is being evaluated. The ''short term'' side effects of thiopurines have been well documented and there have been a number of studies examin- ing the role of thiopurine methyltrans- ferase activity in predicting the risk of these side effects. In this issue of Gut, Kandiel and colleagues 1
Evaluation of Bordetella pertussis-specific immune responses after infection or after different vaccination programs in the framework of the FP7 Child-INNOVAC program. (2010)

info:eu-repo/semantics/nonPublished
Passive bistatic radar using digital video broadcasting terrestrial (DVB-T) receivers as general-purpose software-defined radio receivers (2018)

International audience
Effects of intraventricular methotrexate administration on Cuprizone-induced demyelination in mice (2013)

We previously showed that intrathecal administration of methotrexate slowed disability progression in multiple sclerosis (MS) patients with progressive disease. In general MS patients with progressive disease respond poorly to anti-inflammatory therapies. In order to better understand the mechanism by which methotrexate is protective in progressive MS, we analyzed its impact on the non-inflammatory cuprizone-induced demyelination model. When low-dose methotrexate was administered intracerebroventricularly it reduced demyelination and accumulation of GFAP+ reactive astrocytes in the corpus callosum. Administration of methotrexate after the withdrawal of cuprizone neither delayed remyelination nor influenced the number of astrocytes in the corpus callosum suggesting that methotrexate does not interfere with repair processes in the CNS. Moreover, methotrexate increased the expression of IGF1 in vitro and in vivo, a factor known to protect oligodendrocytes and limit the activation of astrocytes. Our studies show that methotrexate has an impact on pathogenic process in a demyelination model whose pathophysiological basis is not primarily related to inflammatory mechanisms, similar to neurodegenerative mechanisms associated with progressive MS. The pronounced inhibitory influence of methotrexate on the accumulation of astrocytes in the corpus callosum suggests that intrathecal methotrexate modulates astroglial activation in progressive MS possibly by promoting CNS production of IGF1.
TCM Zheng Classification and Clinical Trials (2013)

According to the traditional Chinese medicine (TCM) theory, TCM Zheng (or pattern, syndrome) is an analysis on disease presentation by TCM practitioners. Zheng classification (Bian Zheng) is a traditional diagnostic method to categorize patients' syndromes based on their presented conditions. Currently, combination of Zheng classification and biomedical diagnosis becomes a common model in TCM diagnostics in clinical practice. Clinical treatments of a patient rely on the classification of a specific TCM Zheng. This special issue collects articles describing the clinical trials with TCM Zheng classification, Zheng classification methodology from clinical data, systematic reviews on clinical studies using Zheng classification, and the clinical pharmacological evaluation on TCM interventions using the omics platforms as well as bioinformatics.
Systematic expression profiling of Dpr and DIP genes reveals cell surface codes in <i>Drosophila</i> larval motor and sensory neurons (2022)

In complex nervous systems, neurons must identify their correct partners to form synaptic connections. The prevailing model to ensure correct recognition posits that cell-surface proteins (CSPs) in individual neurons act as identification tags. Thus, knowing what cells express which CSPs would provide insights into neural development, synaptic connectivity, and nervous system evolution. Here, we investigated expression of Dpr and DIP genes, two CSP subfamilies belonging to the immunoglobulin superfamily, in Drosophila larval motor neurons (MNs), muscles, glia and sensory neurons (SNs) using a collection of GAL4 driver lines. We found that Dpr genes are more broadly expressed than DIP genes in MNs and SNs, and each examined neuron expresses a unique combination of Dpr and DIP genes. Interestingly, many Dpr and DIP genes are not robustly expressed, but are found instead in gradient and temporal expression patterns. In addition, the unique expression patterns of Dpr and DIP genes revealed three uncharacterized MNs. This study sets the stage for exploring the functions of Dpr and DIP genes in Drosophila MNs and SNs and provides genetic access to subsets of neurons.
5-Bromo-norborn-2-en-7-one derivatives as a carbon monoxide source for palladium catalyzed carbonylation reactions (2019)

Norbornenone (5b), obtained from the reaction of 2,5-dimethyl-3,4-diphenylcyclopentadienone dimer (3) with bromomaleic anhydride (4b), provides an excellent base-triggered source of carbon monoxide for palladium-catalysed carbonylation reactions. Aminocarbonylation, ketoamide synthesis, and Suzuki-Miyaura reactions of aryl iodides carried out in a two-chamber reaction vessel gave good to excellent yields of carbonylated products.
A theory for the electrophoretic separation of DNA in polymer solutions (1998)

We present a mathematical model of DNA capillary electrophoresis in polymer solutions based on nonentangling collisions between DNA and polymer molecules. Using videomicroscopy images of DNA migrating through polymer solutions, we propose a modified transient entanglement coupling mechanism for DNA separations that includes nonentangling DNA/polymer collisions. We show that a mathematical model based on individual nonentangling DNA/polymer collisions is able to predict the mobilities of DNA in solutions of low molecular mass polymer. We compare the model predictions to mobility data for separations of DNA in a range of concentrations for solutions of both hydroxypropylcellulose (Mw 100,000) and hydroxyethylcellulose (Mw 139,000). The model relies on one fitted parameter, the time constant for the interaction between the DNA and polymer molecules, which is based on the physical properties of DNA and polymers.
A 1-year follow-up study of dynamic magnetic resonance imaging in early rheumatoid arthritis reveals synovitis to be increased in shared epitope-positive patients and predictive of erosions at 1 year (2000)

These results show that dynamic MRI can be used to score synovitis objectively in early RA patients. Synovitis was greater in SE+ patients, suggesting an early genetic influence on joint inflammation, and was predictive for the development of erosions at 1 yr.
Biofabricated film with enzymatic and redox-capacitor functionalities to harvest and store electrons (2013)

Exciting opportunities in bioelectronics will be facilitated by materials that can bridge the chemical logic of biology and the digital logic of electronics. Here we report the fabrication of a dual functional hydrogel film that can harvest electrons from its chemical environment and store these electrons by switching the film's redox-state. The hydrogel scaffold was formed by the anodic deposition of the aminopolysaccharide chitosan. Electron-harvesting function was conferred by co-depositing the enzyme glucose dehydrogenase (GDH) with chitosan. GDH catalyzes the transfer of electrons from glucose to the soluble redox-shuttle NADP(+). Electron-storage function was conferred by the redox-active food phenolic chlorogenic acid (CA) that was enzymatically grafted to the chitosan scaffold using tyrosinase. The grafted CA undergoes redox-cycling reactions with NADPH resulting in the net transfer of electrons to the film where they are stored in the reduced state of CA. The individual and dual functionalities of these films were demonstrated experimentally. There are three general conclusions from this proof-of-concept study. First, enzymatically-grafted catecholic moieties confer redox-capacitor function to the chitosan scaffold. Second, biological materials (i.e. chitosan and CA) and mechanisms (i.e. tyrosinase-mediated grafting) allow the reagentless fabrication of functional films that should be environmentally-friendly, safe and potentially even edible. Finally, the film's ability to mediate the transfer of electrons from a biological metabolite to an electrode suggests an approach to bridge the chemical logic of biology with the digital logic of electronics.
Proteomic Screening of Anaerobically Regulated Promoters from Salmonella and Its Antitumor Applications (2011)

Solid tumors often contain hypoxic and necrotic areas that can be targeted by attenuated Salmonella typhimurium VNP20009 (VNP). We sought to develop a hypoxia- inducible promoter system based on the tumor-specific delivered strain VNP to confine expression of therapeutic gene specifically or selectively within the tumor microenvironment. A hypoxia-inducible promoter - adhE promoter was screened from the hypoxia-regulated endogenous proteins of Salmonella through two-dimensional gel electrophoresis and matrix-assisted laser desorption ionization-time-of-flight/time-of-flight MS-based proteomics approaches. The efficiency and specificity of the selected adhE promoter were validated first in both bacteria and animal tumor models. The adhE promoter could specifically drive GFP gene expression under hypoxia, but not under normoxia. Furthermore, luciferase reporter expression controlled by the system was also confined to the tumors. Finally, we investigated the anticancer efficacy of VNP delivering human endostatin controlled by our adhE promoter system in both murine melanoma and Lewis lung carcinoma models. Our results demonstrated that by the dual effects of tumoricidal and anti-angiogenic activities, the recombinant Salmonella strain could generate enhanced antitumor effects compared with those of unarmed VNP treatment or untreated control. The recombinant VNP could retard tumor growth significantly and extend survival of tumor-bearing mice by inducing more apoptosis and more severe necrosis as well as inhibiting blood vessel density within tumors. Therefore, VNP carrying the endostatin gene under our tumor-targeted expression system holds promise for the treatment of solid tumors.
1..25-Gb s/sup -1/ bidirectional multimode-fibre data link using a dual-purpose vertical-cavity laser &amp; detector (2002)

We demonstrate a high-speed bidirectional data communication link with simple multimode-fibre transceivers. The single-fiber link uses a vertical-cavity device that functions both as an efficient 850-nm laser source and resonant-cavity-enhanced avalanche photodetector. The receiver sensitivity is found to be better than -12 dBm at 1.25 Gb s/sup -1/ and error-free operation is observed for a 500-m half-duplex link at 1.25 Gb s/sup -1/.
Disruption of Individual Members of Arabidopsis Syntaxin Gene Families Indicates Each Has Essential Functions (2001)

Syntaxins are a large group of proteins found in all eukaryotes involved in the fusion of transport vesicles to target membranes. Twenty-four syntaxins grouped into 10 gene families are found in the model plant Arabidopsis thaliana, each group containing one to five paralogous members. The Arabidopsis SYP2 and SYP4 gene families contain three members each that share 60 to 80% protein sequence identity. Gene disruptions of the yeast (Saccharomyces cerevisiae) orthologs of the SYP2 and SYP4 gene families (Pep12p and Tlg2p, respectively) indicate that these syntaxins are not essential for growth in yeast. However, we have isolated and characterized gene disruptions in two genes from each family, finding that disruption of individual syntaxins from these families is lethal in the male gametophyte of Arabidopsis. Complementation of the syp21-1 gene disruption with its cognate transgene indicated that the lethality is linked to the loss of the single syntaxin gene. Thus, it is clear that each syntaxin in the SYP2 and SYP4 families serves an essential nonredundant function.
Differential power processing of photovoltaic systems for high energy capture and reduced cost (2017)

Differential power processing (DPP) module integrated converters are developed to mitigate the effects of the mismatch losses in series connected photovoltaic (PV) strings. This paper focuses on the configurations used in various DPP converter topologies by categorizing them into two main classifications: 1) Maximum power point tracking configurations and 2) voltage balancing configurations. The implementation of different control approaches on the DPP configurations is discussed and the components sizing used in the different DPP topologies are driven under different mismatching scenarios. Experimental results are presented for the ladder configuration to illustrate the need for developing new DPP configurations.
Optimizing the Antimicrobial Synergism of Melaleuca alternifolia (Tea Tree) Essential Oil Combinations for Application against Respiratory Related Pathogens (2023)

Antimicrobial research into the use of <i>Melaleuca alternifolia</i> essential oil has demonstrated broad-spectrum activity; however, much of the research published focuses on identifying the potential of this essential oil individually, rather than in combination for an enhanced antimicrobial effect. This study aimed to determine the antimicrobial activity of four essential oil combinations, all inclusive of <i>M. alternifolia</i>, against nine pathogens associated with the respiratory tract. The minimum inhibitory concentration assay was used to determine the antimicrobial activity of four essential oil combinations, <i>M. alternifolia</i> in combination with <i>Cupressus sempervirens, Origanum majorana, Myrtus communis</i>, and <i>Origanum vulgare</i> essential oils. The interactions between essential oil combinations were analyzed using isobolograms and SynergyFinder 2.0 software to visualize the synergistic potential at varied ratios. The antimicrobial activity of the different combinations of essential oils all demonstrated the ability to produce an enhanced antimicrobial effect compared to the essential oils when investigated independently. The findings of this study determined that isobolograms provide a more in-depth analysis of an essential oil combination interaction; however, the value of that interaction should be further quantified using computational modelling such as SynergyFinder. This study further supports the need for more studies where varied ratios of essential oils are investigated for antimicrobial potential.
An Inorganic Helix [Mn(IPG)(MeOH)]n[PF6]n[‡]: Structural and Magnetic Properties of asyn-anti Carboxylate-Bridged Manganese(II) Chain Involving a Tetradentate Ligand (1999)

The crystal structure of an infinite inorganic chain consisting of MnII and an N-centered tripodal ligand N,N-(2-pyridylmethyl)[(1-methylimidazol-2-yl)-methyl]glycinate is presented. It exhibits a chiral helical structure with a pitch of two monomeric units (each monomeric unit containing one Mn atom). Each manganese is connected to its neighbor through a carboxylate bridge in a syn-anti geometry. Around each manganese center, two carboxylates bind in a cis geometry. This peculiar bridging geometry (syn-anticis) provides a broken-line chain, running in a zig-zag manner along the b axis of the P21 space group. The magnetic properties have been investigated. They show a pseudo-2D magnetic structure, with one major pathway along the chain and an inter-chain minor one. The intrachain coupling is a weak antiferromagnetic interaction (J/k = –0.25). This low value is entirely consistent with the geometry of the bridge. The interchain coupling is a weaker antiferromagnetic coupling (J′/k = –0.11) and could be mediated through π-π interactions between pyridine and imidazole from two adjacent helixes.