gebhart/patrepeval huggingface dataset:
Regulation of the Alkane Hydroxylase CYP153 Gene in a Gram-Positive Alkane-Degrading Bacterium, Dietzia sp. Strain DQ12-45-1b (2015)

CYP153, one of the most common medium-chain n-alkane hydroxylases belonging to the cytochrome P450 superfamily, is widely expressed in n-alkane-degrading bacteria. CYP153 is also thought to cooperate with AlkB in degrading various n-alkanes. However, the mechanisms regulating the expression of the protein remain largely unknown. In this paper, we studied CYP153 gene transcription regulation by the potential AraC family regulator (CypR) located upstream of the CYP153 gene cluster in a broad-spectrum n-alkane-degrading Gram-positive bacterium, Dietzia sp. strain DQ12-45-1b. We first identified the transcriptional start site and the promoter of the CYP153 gene cluster. Sequence alignment of upstream regions of CYP153 gene clusters revealed high conservation in the -10 and -35 regions in Actinobacteria. Further analysis of the β-galactosidase activity in the CYP153 gene promoter-lacZ fusion cell indicated that the CYP153 gene promoter was induced by n-alkanes comprised of 8 to 14 carbon atoms, but not by derived decanol and decanic acid. Moreover, we constructed a cypR mutant strain and found that the CYP153 gene promoter activities and CYP153 gene transcriptional levels in the mutant strain were depressed compared with those in the wild-type strain in the presence of n-alkanes, suggesting that CypR served as an activator for the CYP153 gene promoter. By comparing CYP153 gene arrangements in Actinobacteria and Proteobacteria, we found that the AraC family regulator is ubiquitously located upstream of the CYP153 gene, suggesting its universal regulatory role in CYP153 gene transcription. We further hypothesize that the observed mode of CYP153 gene regulation is shared by many Actinobacteria.
Application of PM type DMPM in hybrid electric vehicle (2010)

This paper presents a new full hybrid system with a PM type DMPM using a new mechanism in the decoupling of the internal combustion engine (ICE) optimal working points and the power train output shaft operation points. In this paper, the working points of this system are explained. The comparison of system efficiencies is made. The results suggest that the system proposed can obtain the same or even higher efficiency than that of Toyota Hybrid System using high speed planetary gear set. The torque coupling and decoupling of the inner and outer motors of DMPM during the steady and start-stop transient states are analyzed. A control scheme is proposed. The research results are used to drive a 38kW/52kW PM type DMPM system loaded on a SUV of about 2700kg. The maximum speed of the SUV reaches 122.5km/h.
Capturing Cultural Differences between UK and Malaysian Drivers to Inform the Design of In-Vehicle Navigation Systems (2017)

Attending to cultural diversity is important for products and technology intended for global placement, such as automobiles, yet many products (and associated interfaces) lack genuine cultural differentiation. For example, in-vehicle navigation systems are typically identical in form and function across world markets, differing only in the local language and map database. To capture and explore culturally-salient design factors, we utilised a scenario-based design methodology, involving 6 experienced drivers from the UK and Malaysia. Participants were asked to portray their ideal navigation system interface designs – by drawing pictograms and devising accompanying spoken messages – to direct drivers along 3 prescribed routes in the UK, Malaysia and Japan. Routes were presented using video and paper maps, with the order of presentation counterbalanced between groups; participants were not told in advance from which country each route was derived. Proposed designs highlight differences at a country level, which are consequently interpreted from a cultural perspective. For example, Malaysian drivers included a higher density of navigational elements in their designs, particularly in their home environment, compared to UK drivers. Malaysian drivers also created more incremental designs, particularly on the approach to a manoeuvre, suggesting a desire for greater navigational support at this point in the journey. Landmarks were consistently incorporated in designs, but differences were noted in cultural salience. Additionally, the phrasing of instructions (e.g. “go straight on”), nomenclature for road elements (e.g. ‘roundabout’) and distance declaration conventions (e.g. units) differed at a country level. The findings can be used to inform the design of culturally-attuned in-vehicle navigation systems.
Theoretical and simulated performance for a novel frequency estimation technique (1993)

A low complexity, open-loop, discrete-time, delay-multiply-average (DMA) technique for estimating the frequency offset for digitally modulated MPSK signals is investigated. A nonlinearity is used to remove the MPSK modulation and generate the carrier component to be extracted. Theoretical and simulated performance results are presented and compared to the Cramer-Rao lower bound (CRLB) for the variance of the frequency estimation error. For all signal-to-noise ratios (SNR's) above threshold, it is shown that the CRLB can essentially be achieved with linear complexity.
Overload control in SIP servers: Evaluation and improvement (2010)

The Session Initiation Protocol (SIP) has gained momentum and is being widely used both in the Internet and Next Generation Telecommunications network as the core signaling protocol. SIP operation relies on SIP servers which are responsible for forwarding of SIP messages. It has been shown that the performance of SIP servers is largely degraded during overload conditions due to the built in message retransmission mechanism of SIP. This is an obstacle in wide deployment of SIP for a realistic situation. In this paper we propose a distributed and adaptive window based overload control algorithm, which controls the amount of calls that are forwarded to a downstream SIP server in an attempt to prevent it from being overloaded. Our scheme uses the call establishment delay as a measure of the amount of load on the downstream server and unlike other methods does not rely on explicit feedback. Using simulations we show that our proposed method performs better than a commonly used overload control algorithm and exhibits fast convergence and is stable.
An Analytical Method for Calculating Microstrip Transmission Line Parameters (1970)

When finite difference techniques are applied to the solution of coupled-line parameters for microstrip transmission lines, the computation times become prohibitively long. This paper describes an analytical method for calculating such parameters if TEM propagation is assumed. The method is applicable to a wide range of planar TEM mode transmission line calculations where the boundaries and dielectric interfaces are rectilinear. The accuracy of the analytical technique has been verified by experimental work on 10 dB and 6 dB coupled-line directional couplers and a parallel-coupled Cohn type 6 resonator filter.
A cold-cathode fluorescent lamp driver circuit with synchronous primary-side dimming control (1998)

A novel synchronous primary-side dimming control scheme is proposed and tested for a cold-cathode fluorescent lamp (CCFL) driver circuit for liquid crystal display (LCD) backlight illumination display applications. This new control scheme features high efficiency, even-dimming sensitive adjustment, even-brightness control for a two-lamp system, less lamp flickering problems, stable feedback control and simplicity. An analysis of the circuit is given, from which a design example is presented.
Improved Method for Confirmation of Identity of Aflatoxins B1 and M1 in Dairy Products and Animal Tissue Extracts (1981)

A method is described for confirming the identity of aflatoxins B1 and M1 in dairy products and liver extracts on a thin layer plate. Extracts and standards containing aflatoxins B1 and M1 are spotted on 10 x 10 cm plates, which are developed 2-dimensionally in mixtures of isopropanol-acetone-chloroform. After the first development, trifluoroacetic acid-hexane (1 + 4) is sprayed on that part of the plate containing the separated extract components and the underdeveloped standard spots of B1 and M1, and the plate is heated 6-8 min at 75 degrees C. Then the plate is developed in a second direction, and the reaction products of B1 and M1 with trifluoroacetic acid from the extract are compared with the same derivatives of the respective standards. The method has been used successfully on extracts of milk, cheese, and liver containing 0.1 ng B1 or M1/g and can be completed in 35-45 min.
ON ACCRETIVE BOUNDARY PROBLEMS OF THE SECOND ORDER (1965)

Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans the biological, physical, and social sciences.
Integrity testing of microfiltration membranes. (1984)

The diffusion test in combination with the BP test provides decisive information for the acceptance of a filter element in sterile filtration. The single point diffusion test as usually performed is capable of detecting a flaw of 5 to 10 μm in size for large area membrane filters. Because of the amount and variability of gas flow through large area membrane filters, flaws can be masked which have impact on filtrate quality. The detectability of such hidden flaws can be improved by the proposed Flow Ratio method, where test gas flow through the wetted membrane filter element is determined at two different challenge pressures. The Bubble Point test is capable of detecting oversize pores also in large area membrane filters provided that the BP is determined with highest sensitivity. Integrity tests can be performed at temperatures and in wetting agents different from what is specified by the membrane manufacturer provided that temperature can be maintained stable for the duration of the test and that changes in diffusion rate and BP are considered. Theoretical computations show that the minimum retention value which can be considered realistic is directly proportional to the water permeability of the filter element and proportional to the sensitivity of the diffusion test employed. Integrity tests performed from the upstream side of the filter system have the advantage of not interfering with the clean, sterile downstream side. They can substitute downstream volumetric methods provided their sensitivity is comparable. As the upstream pressure loss rate caused by gas loss through the filter element depends also on the size of the upstream volume of the filter system, pressure loss data should be converted to decisive filter dependent volumetric gas loss data. Even slight temperature changes cause significant pressure changes in the filter system. Thus the upstream integrity test must be capable of detecting such disturbances. In critical applications where the desired degree of integrity cannot be ensured by the integrity test method, two, equally rated filters should be used in series.
Toward a Task-driven Intelligent GUI Adaptation by Mixed-initiative (2020)

Adapting the user interface (UI) to the changing context of use is intended to support the interaction effectiveness and sustain UI usability. However, designing and/or processing UIs adaptation at design time does not encompass real situation requirements. Adaptation should have a cross-cutting and low-cost impact on software patterning and appearance with regard to the situation and the ambient-context. To meet this requirement, we present TADAP proposal for run-time adaptive and adaptable UI based user feedbacks and machine learning. It allows a task-driven adaptation of the user interface (UI) at runtime by mixed-initiative. The particularity of TADAP is the utilization of Machine Learning potential to support context-aware runtime adaptation within model-driven UI. Further, TADAP allows the UI adaptation by mixed-initiative (User and System) considering the user preferences (implicit and explicit) during an interaction. Such a mixed-initiative runtime UI-adaptation tool provides recommendations on how to personalize the UI. Further, it has the ability to track real-time users’ interventions and learn their preferences. Diverse tests were performed and showed TADAP as a promising initiative for intelligent model-driven UI adaptation.
Effect of Bisphosphonates on the Levels of Rankl and Opg in Gingival Crevicular Fluid of Patients With Periodontal Disease and Post-menopausal Osteoporosis. (2015)

The Receptor activator of nuclear factor-kappa B ligand (RANKL)/RANK/Osteoprotegerine (OPG) system has been proposed as essential for osteoclast biology and identified as key part in regulating the physiology and pathology of the skeletal system. The study of the RANKL/RANK/OPG system has increased the understanding of the mechanisms involved in the bone remodeling process, especially in postmenopausal osteoporosis and periodontal disease. Bisphosphonates have become the mainstay of the treatment and prevention of post-menopausal osteoporosis. They inhibit the formation and dissolution of calcium phosphate crystals in bone and also osteoclasts, thus reducing bone turnover.Current investigations relate osteoporosis with the appearance and progression of periodontal disease. Although the etiology of both is different, the bone loss present in both shares several characteristics. Thus, therapy used for osteoporosis can be considered of value in the treatment of periodontal disease. The aim of this study was to evaluate the levels of RANKL, OPG and their relationship in gingival crevicular fluid (GCF) in patients with periodontal disease and postmenopausal osteoporosis/ osteopenia in relation to consumption of bisphosphonates. We studied 66 periodontal active sites obtained from 17 post- menopausal women patients aged between 45-70 years old with osteoporosis/osteopenia and periodontal disease. GCF samples were collected using sterile filter paper strips. To determine the concentration of RANKL and OPG, a commercial ELISA assay was used. The values of RANKL, OPG and their ratio (RANKL/ OPG) were compared with Mann-Whitney U Test. The values of RANKL, OPG and their ratio obtained in patients with osteoporosis/osteopenia and periodontal disease with or without bisphosphonates treatment showed no differences. Bisphosphonates do not alter the concentration of RANKL and OPG and their ratio in the GCF of patients with osteoporosis/ osteopenia and periodontal disease, probably because these cytokines may not be the main target of bisphosphonates to inhibit bone resorption in periodontal disease.
Polycrystalline Silicon Thin Film Transistors (2010)

Abstract not Available.
Theory (Instantaneous Power Theory and Applications to Power Conditioning; Akagi, H. et al; 2007) [Book Review] (2007)

This new book presents a deep review of various power theories and shows how the instantaneous active and reactive power theory provides an important basic knowledge for understanding and designing active filters for power conditioning. The book consists of six chapters covering the following topics and more: instantaneous power theory; shunt active filters; hybrid and series active filters; and combined series and shunt power conditioners. The book is easy to read and each chapter ends with a summary and list of references. The book perfectly fills the gap on the power electronics book market. It is an extremely attractive reference book for research and development engineers who are interested in design of modern active power filters and conditioners as well as flexible ac transmission systems. It can also be recommended for advanced senior-level courses as well as for undergraduate courses.
Linguistic Harbingers of Betrayal: A Case Study on an Online Strategy Game (2015)

Vlad Niculae, Srijan Kumar, Jordan Boyd-Graber, Cristian Danescu-Niculescu-Mizil. Proceedings of the 53rd Annual Meeting of the Association for Computational Linguistics and the 7th International Joint Conference on Natural Language Processing (Volume 1: Long Papers). 2015.
Nonplatinum Topotecan Combinations Versus Topotecan Alone for Recurrent Ovarian Cancer: Results of a Phase III Study of the North-Eastern German Society of Gynecological Oncology Ovarian Cancer Study Group (2008)

Nonplatinum topotecan combinations do not provide a survival advantage over topotecan alone in women with relapsed ovarian cancer.
Contraception for HIV-infected women. (1997)

Decisions regarding the use of contraception for HIV-infected women are complicated by changing opinions regarding prevention and treatment. In addition, there is also interplay between the two risks involved: vertical HIV transmission in the event of pregnancy, and horizontal transmission to an uninfected partner. Unfortunately, the methods of contraception that have historically best protected against HIV transmission, such as condoms, have also been least effective in preventing pregnancy. Moreover, studies have shown that HIV-positive women who use a more effective method of contraception are less likely to also use a condom, even with an uninfected partner. While two different methods of contraception are advisable to deal with the two separate risk factors, it is still unclear which methods are safest and most effective.
Hemiplegic shoulder pain (HSP): Natural history and investigation of associated features (1996)

The prevalence of hemiplegic shoulder pain (HSP) and associated factors was studied in patients with a stroke followed for 6 months after discharge from hospital. A questionnaire was used to evaluate shoulder symptoms and an examination of the shoulder and arm was carried out three times over 6 months. A total of 108 patients were studied with a mean age of 71 years. Sixty-nine patients (63.8%) developed HSP at some time during the study period. The number with HSP was 39 at discharge from hospital, 59 at 8 weeks post-discharge and 36 at 6 months. Nine carers reported lifting the patient by pulling on the hemiplegic arm, even though six of them had received advice about correct lifting techniques. Reduced shoulder shrug was associated with HSP at all times and reduced pinch grip was also associated with HSP at discharge from hospital. Patients who required help with transfers were more likely to suffer with HSP. There was no difference in the prevalence of HSP in patients treated at the day hospital compared to those who received domiciliary physiotherapy. It is concluded that HSP is common after a stroke and the prevalence increases in the first weeks after discharge from hospital. Stroke patients and their carers need advice about correct handling of the hemiplegic arm, and more work is required to ensure that correct handling occurs after discharge in patients at high risk of this unpleasant complication.
Agent-based Automatic Camera Placement for Video Surveillance Systems (2010)

In this paper, we propose an optimal camera placement using agent-based simulation. To derive importance of space and to cover the space efficiently, we accomplished an agent-based simulation based on classification of space and pattern analysis of moving people. We developed an agent-based camera placement method considering camera performance as well as space priority extracted from path finding algorithms. We demonstrate that the method not only determinates the optimal number of cameras, but also coordinates the position and orientation of the cameras with considering the installation costs. To validate the method, we compare simulation results with videos of real materials and show experimental results simulated in a specific space.
Trajectories of Mediterranean Diet Adherence and Risk of Hypertension in China: Results from the CHNS Study, 1997–2011 (2018)

Evidence indicates that longitudinal changes in dietary patterns may predict variations in blood pressure (BP) and risk of incident hypertension. We aimed to identify distinct trajectories in the levels of Mediterranean diet adherence (MDA) in China and explore their association with BP levels and hypertension risk using the China Health and Nutrition Survey 1997⁻2011 data. Three levels of MDA were constructed. The trajectories in these levels were constructed using group-based trajectory modeling. A Cox proportional hazards model was used to measure the association between MDA trajectory groups and the risk of incident hypertension after adjusting for covariates. Finally, 6586 individuals were included. Six distinct MDA trajectory groups were identified: persistently low and gradual decline; rapidly increasing and stabilized; persistently moderate; slightly increasing, steady, and acutely descending; slightly decreasing and acutely elevated; and persistently high. The systolic BP and diastolic BP were significantly lower in trajectory groups with rapidly increasing and stabilized MDA; slightly increasing, steady, and acutely descending MDA; and persistently high MDA. Cox regression analysis showed that the risks of developing hypertension were relatively lower in the group with slightly increasing, steady, and acutely descending MDA (hazard ratio (HR) = 0.17, 95% confidence interval (CI): 0.09⁻0.32) and the group with rapidly increasing and stabilized MDA (HR = 0.32, 95% CI: 0.23⁻0.42), but the risk was the highest in the trajectory with persistently moderate MDA (HR = 0.96, 95% CI: 0.84⁻1.08). In conclusion, MDA in China was categorized into six distinct trajectory groups. BP was relatively lower in trajectory groups with initially high or increasing MDA levels. Greater MDA was significantly associated with a lower risk of developing hypertension.
Sequencing CONWIP flow-shops: Analysis and heuristics (2001)

In this paper, we address the backlog sequencing problem in a flow-shop controlled by a CONWIP production control system, with the objective to minimize the makespan. We characterize the problem and analyse its similarities and differences with the unconstrained permutation flow-shop problem. A comparison of some well-known flow-shop heuristics is carried out, and a simple and fast dispatching rule is proposed. Regarding the more simple and faster heuristics, the proposed dispatching rule outperforms those commonly used for the unconstrained permutation flow-shop problem.
Patterns and scaling properties in a ballistic deposition model (1993)

We study a ballistic deposition model in 1+1 dimensions in which the incident angles (the angles between the incident trajectories and the substrate) of incoming particles and randomly distributed in the range [\ensuremath{\theta},\ensuremath{\pi}-\ensuremath{\theta}]. We find a sharp morphological transition at a critical angle ${\mathrm{\ensuremath{\theta}}}_{\mathit{c}}$\ensuremath{\approxeq}10 \ifmmode^\circ\else\textdegree\fi{}. For \ensuremath{\theta}>${\mathrm{\ensuremath{\theta}}}_{\mathit{c}}$, the scaling properties of the interface are described by the Kardar-Parisi-Zhang equation. For \ensuremath{\theta}${\mathrm{\ensuremath{\theta}}}_{\mathit{c}}$, the shadowing effect leads to a very different morphology. We determine the scaling properties of this new universality class numerically and analytically.
Implementation of Template Matching Based ECG Compression Algorithm for Mobile Application (2013)

In this paper, a template based ECG compression algorithm for mobile device application is proposed and implemented.Adaptive threshold is applied for good R-peak detection accuracy.Template for PQ interval, QRS complex, ST interval is created.Only template code that closely matched with the input signal is saved. The determining factor for "closely matched" is based on the calculation of MSE value after comparing the template with each of the intervals (PQ interval, QRS complex and ST interval) with real time input ECG signal.The performance of algorithm is evaluated by using the Massachusetts Institute of Technology-Boston's Beth Israel Hospital Normal Sinus Rhythm Database and different sampling record. The highest compression ratio is 15.2:1. The accuracy of the R-peak detection is 100%.