gebhart/patrepeval huggingface dataset:
Umbilical and Uterine Artery Flow Velocity Waveforms in Pregnant Women With Systemic Lupus Erythematosus Treated With Aspirin and Glucocorticosteroids (1992)

Pregnancy in systemic lupus erythematosus (SLE) is at high risk to the mother and fetus. Impaired utero-placental perfusion may increase fetal loss and intrauterine growth retardation. We assessed the changes in impedance to blood flow in the umbilical and uterine arteries in five patients with SLE treated with low dose aspirin and corticosteroids, using Doppler ultrasound longitudinally throughout pregnancy. Blood flow velocity waveforms of the umbilical and uterine arteries were studied by transabdominal and transvaginal Doppler ultrasound, respectively. Resistance index (RI) was measured every two to four weeks from week 10 to term, and the values obtained were compared to those of normal pregnancies. All five patients delivered uneventfully. One neonate was delivered at 36 weeks (2550 g) and one neonate was growth retarded (1900 g at 38 weeks). Three women delivered at 39 weeks (3585 g, 2850 g, and 2800 g). Most umbilical artery RI values obtained throughout pregnancy were above the 95th percentile of normal pregnancies. The highest values of RI of the umbilical artery were assessed in the case of fetal growth retardation. However, most measurements of RI of the uterine artery were under the 95th percentile of normal. The improved pregnancy outcome in patients with SLE treated with aspirin and corticosteroids seems to correlate with their normal uterine artery flow velocity wave forms.
Mechanized large-area radiological surveillance (1991)

At the Hanford site, ground surfaces overlying old, inactive waste disposal sites, such as burial grounds, cribs, ponds, and ditches, became contaminated, mostly as a result of penetration into buried waste by deep-rooted vegetation, such as tumbleweeds. Surface stabilization of these contaminated surfaces was performed by adding up to a meter of soil to the sites and revegetating with shallow-rooted grasses, which discouraged the establishment and growth of deep-rooted vegetation. As the total size of the stabilized areas grew, it became apparent that the manual methods used for semiannual radiological surveys would soon become cost-prohibitive. In 1983, the Hanford engineering department was asked to develop a vehicle that could traverse the stabilized areas to perform environmental level surveys without damaging the newly planted vegetation. The resulting prototype surveillance system, called the mobile surface contamination monitor (MSCM), became operational for testing purposes in 1984.
Deformation of a two-dimensional drop at non-zero Reynolds number in time-periodic extensional flows: numerical simulation (2001)

The shape of a two-dimensional viscous drop deforming in several time-dependent flow fields, including that due to a potential vortex, has been studied. Vortex flow was approximated by linearizing the induced velocity field at the drop centre, giving rise to an extensional flow with rotating axes of stretching. A generalization of the potential vortex, a flow we have called rotating extensional flow , occurs when the frequency of revolution of the flow is varied independently of the shear rate. Drops subjected to this forcing flow exhibit an interesting resonance phenomenon. Finally we have studied drop deformation in an oscillatory extensional flow . Calculations were performed at small but non-zero Reynolds numbers using an ADI front-tracking/finite difference method. We investigate the effects of interfacial tension, periodicity, viscosity ratio, and Reynolds number on the drop dynamics. The simulation reveals interesting behaviour for steady stretching flows, as well as time-dependent flows. For a steady extensional flow, the drop deformation is found to be non-monotonic with time in its approach to an equilibrium value. At sufficiently high Reynolds numbers, the drop experiences multiple growth–collapse cycles, with possible axes reversal, before reaching a final shape. For a vortex flow, the long-time deformation reaches a steady value, and the drop attains a revolving steady elliptic shape. For rotating extensional flows as well as oscillatory extensional flows, the maximum value of deformation displays resonance with variation in parameters, first increasing and then decreasing with increasing interfacial tension or forcing frequency. A simple ODE model with proper forcing is offered to explain the observed phenomena.
Novel Synthesis of Pyridopyrimidine Diones (1986)

P h e n y l s u l p h o n y l o x y ) q u i n o l i n i m i d e ( I ) reacts with different nucleaphiles t o give 11-VIII.It was proved that the nucleophilic attack occurs at the m o r e electra-positive carbonyl group t o give only one product in good yields.Pyridopyrimidine derivatives possessing long lasting diuretic and selective n a trivertic activitiesZ and some of them having analgesic antiinflammatory and cen-3 tral nervous system depressing activities .In this w o r k , we have synthesized unreported pyrido[3,2-dlpyrimidine-2,4-diones through the reaction o f N-(phenylsul-phony1oxy)quinolinimide (I) with different nucleophiles.Ammonolysis of N-(phenylsulphonylaxy)quinolinimide(I) with dry ammonia a t r o o m temperature gives a mixture o f 2 -c a r b a m o y l -3 -p y r i d y l u r e a ( I 1 ) and 1H,3H-pyrido-[3,2-dlpyrimidine-2,s-dione(II1).Fusion of I1 gives I11 with evolution of ammonia in 98% yield.corn* 0 I I1 I11 0 Structure of I1 and I11 was confirmed on the basis of elemental analyses and spectroscopic data.The ' H n m r spectrum of I1 (DMSO, 250 MHz) shored the following signals: 6.67 (NH2 in the 3-position, 2H, br s), 7.45-7.50(HB, lH, d of d), 7.8 4 and 8.34 (NH2 in the 2-position , ZH, two br s), 8.13-8.16(HA, lH, d of d), 8.79-8.83(HC, lH, d of d) and 10.9 (NH, l H , s ) .Mass spectrum of I1 showed molecular 5 ion a t mlz 1 8 0 and the latter undergoes the fragmentation pathways ( a a n d b) as s h o w n i n S c h e m e 1.
Generation of coherent optical pulses (1977)

Get PDF Email Share Share with Facebook Tweet This Post on reddit Share with LinkedIn Add to CiteULike Add to Mendeley Add to BibSonomy Get Citation Copy Citation Text C. L. Hayes and L. M. Laughman, "Generation of coherent optical pulses," Appl. Opt. 16, 263-264 (1977) Export Citation BibTex Endnote (RIS) HTML Plain Text Citation alert Save article
X-ray powder diffraction analysis and initial Rietveld characterization of SmAlSi and SmAlGe (2004)

The structures of SmAlSi and SmAlGe were determined by the powder diffraction method. These compounds have a tetragonal structure of LaPtSi type, which is a ternary substitutional variant of α -ThSi 2 . Both prototype structures have the same extinction rules, and as a result, the choice of the structural type must be based on very careful examination of the peak intensities. This was done with the aid of a Rietveld refinement, which indicates a better fit of the LaPtSi structure.
Molecular Mechanisms of Target Recognition in an Innate Immune System: Interactions Among Factor H, C3b, and Target in the Alternative Pathway of Human Complement (2000)

In the alternative pathway of complement (APC) factor H is the primary control factor involved in discrimination between potential pathogens. The APC deposits C3b on possible Ags, and the interaction with factor H determines whether the initial C3b activates the APC. Factor H is composed of a linear array of 20 homologous short consensus repeats (SCR) domains with many functional sites. Three of these sites are involved in binding C3b and regulating complement activation; others bind to sialic acid and/or heparin and are responsible for host recognition. Using site-directed mutations we have examined the contributions of each of these sites to target discrimination and to functional activities of factor H. Decay acceleration by SCR1-4 of C3/C5 convertases bound to nonactivators was strongly dependent on SCR domains 11-15 and 16-20. Loss of these regions caused a 97% loss of activity, with SCR16-20 being the most critical (>90% loss). On APC activators the pattern of site usage was different and unique on each. On yeast, deletion of the 10 C-terminal domains (SCR11-20) had no effect on specific activity. On rabbit erythrocytes, this deletion caused loss of 75% of the specific activity. An examination of binding affinity to C3b on the four cell types demonstrated that factor H exhibits a unique pattern of SCR involvement on each cell. The results reveal a complex molecular mechanism of discrimination between microbes and host in this ancient innate defense system and help explain the different rates and intensities of APC activation on different biological particles.
Carvacrol Protects against Hepatic Steatosis in Mice Fed a High-Fat Diet by Enhancing SIRT1-AMPK Signaling (2013)

We investigated the protective effect of carvacrol against high-fat-diet-induced hepatic steatosis in mice and the potential underlying molecular mechanisms. Mice were fed a normal diet, high-fat diet, or carvacrol-supplemented high-fat diet for 10 weeks. Compared to mice fed the high-fat diet, those fed the carvacrol-supplemented diet showed significantly lower hepatic lipid levels and reduced plasma activities of alanine aminotransferase and aspartate aminotransferase and plasma concentrations of monocyte chemoattractant protein 1 and tumor necrosis factor α . Carvacrol decreased the expression of LXR α , SREBP1c, FAS, leptin, and CD36 genes and phosphorylation of S6 kinase 1 protein involved in lipogenesis, whereas it increased the expression of SIRT1 and CPT1 genes and phosphorylation of liver kinase B1, AMP-activated protein kinase, and acetyl-CoA carboxylase proteins involved in fatty acid oxidation in the liver of mice fed the high-fat diet. These results suggest that carvacrol prevents HFD-induced hepatic steatosis by activating SIRT1-AMPK signaling.
Alguns aspectos da biologia do serrador, <i>Oncideres dejeani </i>Thompson, 1868 (Coleoptera: Cerambycidae). (1996)

Realizou-se este trabalho objetivando determinar alguns parâmetros comparativos da biologia do serrador, Oncideres dejeani Thomson,1868 (Coleoptera: Cerambycidae) sobre aroeira preta, Lithraea brasiliensis L. March (Anacardiaceae) e pau de leite, Sebastiania brasiliensis Spreng. (Euphorbiaceae), em São Sepé - RS, durante o período 1989-1990. Mediu-se o comprimento e a largura do orifício de emergência dos adultos do serrador e, o comprimento e volume da galeria larval-pupal. O orifício de emergência do adulto de O. dejeani apresenta formato ovalado em pau de leite e quase circular em aroeira preta. A larva se desenvolve em galhos de vários diâmetros, independente da espécie de planta hospedeira, consome igual volume de madeira e constroi galeria de comprimento similar nas duas espécies botânicas estudadas.
Identification of host‐specific colonization factors of <i>Salmonella enterica</i> serovar Typhimurium (2004)

The severity of infections caused by Salmonella enterica serovar Typhimurium varies depending on the host species. Numerous virulence genes have been identified in S. Typhimurium, largely from studies in mice, but their roles in infections of other species remain unclear. In the most comprehensive survey of its kind, through the use of signature-tagged mutagenesis of S. Typhimurium we have identified mutants that were unable to colonize calf intestines, mutants unable to colonize chick intestines and mutants unable to colonize both species. The type three secretion systems encoded on Salmonella pathogenicity islands (SPIs) 1 and 2 were required for efficient colonization of cattle. However, disruption of these secretion systems only caused a minor defect in S. Typhimurium colonization of chicks. Transposon insertions in SPI-4 compromised S. Typhimurium colonization of cattle, but not chicks. This is the first data confirming a role for SPI-4 in pathogenesis. We have also been able to ascribe a role in colonization for cell surface polysaccharides, cell envelope proteins, and many 'housekeeping' genes and genes of unknown function. We conclude that S. Typhimurium uses different strategies to colonize calves and chicks. This has major implications for vaccine design.
Der Text und seine Medialisierung. Literatur- und Buchwissenschaft im Kontext der postmodernen Theoriediskussion (1999)

Mesurant la place de la science de la culture entre l'histoire de la societe et le deconstructionnisme caracteristiques du debat socio-politique sur les tendances du developpement culturel et textuel (Derrida, Foucault), l'A. examine les processus de la communication litteraire definis comme autant de structures fonctionnelles de la societe: la distribution, la production, la reception et la selection, participant a la mediatisation esthetique et economique du texte au-dela de toute rhetorique historique ou de toute determination socio-historique
Microwave‐Assisted Olefin Metathesis (2007)

Abstract The beneficial effect of microwave irradiation instead of classical thermal conditions in olefin metathesis reactions is illustrated through a series of literature examples of ring‐closing‐metathesis and cross‐metathesis reactions. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008)
Mucosal transport of Eimeria tenella in the cecum of the chicken. (1982)

A study of the early life history of Eimeria tenella with the electron microscope confirmed that sporozoites do not directly enter the enterocytes of the crypts, in which they develop, but are carried there by host cells. However, these cells are not macrophages, as previously thought, but intraepithelial lymphocytes. The evidence presented demonstrates that sporozoites first penetrate surface enterocytes and then enter intraepithelial lymphocytes that leave the epithelium, pass through the lamina propria and enter the crypts.
Complete deletion of the androgen receptor gene: definition of the null phenotype of the androgen insensitivity syndrome and determination of carrier status (1992)

The molecular basis of androgen insensitivity was investigated in a family with the complete form of the syndrome. Polymerase chain reaction amplification and Southern blot analysis of genomic DNA revealed a deletion of the entire androgen receptor (AR) gene in affected individuals. The carrier status of female members of this family was examined using a HindIII restriction fragment length polymorphism associated with the AR gene. Obligate carriers were hemizygous for one of the two alleles at this locus, while heterozygosity for the polymorphic alleles, implying the presence of two copies of the AR gene, indicated noncarrier status. This conclusion was supported by gene dosage studies using comparative densitometric analysis of Southern blots hybridized simultaneously with an AR cDNA probe and a control cDNA probe from an unrelated gene. Finally, the pattern of inheritance of another X-linked DNA polymorphism allowed us to conclude that the original mutation had occurred in the germ line of the maternal great-grandfather of the index patient. Although rare, complete deletion of the AR gene is of particular importance in terms of correlation between molecular defect and phenotype, as it represents the quintessential form of complete androgen insensitivity, the null phenotype.
Purinergic Signalling in Neuron–Glia Interactions (2006)

Neurons are delicate elements unable to withstand prolonged exposure to the many toxic factors that gain access to the CNS or which are made by activated leukocytes. The well-being of neurons and their functional properties are dependent on glial cells. Microglia have a unique role in this context because they are involved in both neuronal support and immunological defence. We now know that neuron-microglia communication is bidirectional: neurons and microglia continuously exchange messages and integrate information received from neighbouring cells. It is now generally accepted that purinergic signalling is a key pathway in this continuous flow of information in health and disease. Release of ATP from neurons directly modulates microglial cell function eliciting secretion of neurotrophic or, in some cases, neurotoxic factors that deeply affect neuronal physiology. Purinergic stimulation of microglia P2 receptors might in turn elicit a burst of ATP release that feeds back onto the neurons. Development of sophisticated techniques for the measurement of extracellular ATP now makes possible real-time measurement of ATP release into the pericellular space and allows validation of the purinergic hypothesis for neuron-microglia signalling.
Effects of battlefield display frames of reference on navigation tasks, spatial judgements, and change detection (2006)

This paper describes an experiment which illustrates the cause of 'cognitive tunnelling' as it affects information gathering and perception-based task performance in computer-generated terrain displays of varying frames of reference. Cognitive tunnelling refers to the effect where observers focus attention on information from specific areas of a display to the exclusion of information presented outside these areas. Previous research suggests that cognitive tunnelling is induced by more immersive or egocentric visual displays. Results from our preceding study suggested that an immersed split-screen display induces cognitive tunnelling and results in poorer information extraction and situation awareness than an exocentric display of the same information. The current study determined that failure of the observers to integrate information across the two views of the immersed display led to the cognitive tunnelling effect. Cognitive tunnelling was also affected by primacy of information initially presented within the larger egocentric view in the immersed display.
Edge Intelligence: On-Demand Deep Learning Model Co-Inference with Device-Edge Synergy (2018)

As the backbone technology of machine learning, deep neural networks (DNNs) have have quickly ascended to the spotlight. Running DNNs on resource-constrained mobile devices is, however, by no means trivial, since it incurs high performance and energy overhead. While offloading DNNs to the cloud for execution suffers unpredictable performance, due to the uncontrolled long wide-area network latency. To address these challenges, in this paper, we propose Edgent, a collaborative and on-demand DNN co-inference framework with device-edge synergy. Edgent pursues two design knobs: (1) DNN partitioning that adaptively partitions DNN computation between device and edge, in order to leverage hybrid computation resources in proximity for real-time DNN inference. (2) DNN right-sizing that accelerates DNN inference through early-exit at a proper intermediate DNN layer to further reduce the computation latency. The prototype implementation and extensive evaluations based on Raspberry Pi demonstrate Edgent's effectiveness in enabling on-demand low-latency edge intelligence.
Stripper foil mechanism for the K1200 superconducting cyclotron (2001)

The Coupled Cyclotron Facility at MSU comprises two superconducting cyclotrons, the K500 (injector) and the K1200 (booster). Both cyclotrons are of the compact design with three hills and three dees in the valleys. The beam from the K500 is injected in the K1200 and stripped to a high charge state inside one of the dees of the cyclotron. The stripper mechanism consists of 31 foil holders attached to a bicycle chain, mounted on a moving platter. A complicated design was necessary to fit all the hardware necessary to do foil exchange in the tight space inside the dee. Five different hydraulic cylinders move the foil to the stripping position, exchange foils within the stripper chain, and position the foils in the loading position. We describe in the paper the mechanical design as well as the control programs developed for it.
2,2′-Dihydroxybiphenyl-3,3′-dicarbaldehyde dioxime (2009)

The mol-ecule of the title compound, C(14)H(12)N(2)O(4), lies across a crystallographic inversion centre situated at the mid-point of the C-C intra-annular bond. The mol-ecule is not planar, the dihedral angle between the aromatic rings being 50.1 (1)°. The oxime group is in an E position with respect to the -OH group and forms an intra-molecular O-H⋯N hydrogen bond. In the crystal structure, inter-molecular O-H⋯O hydrogen bonds link mol-ecules into chains propagating along [001]. The crystal structure is further stabilized by inter-molecular stacking inter-actions between the rings [centroid-to-centroid distance = 3.93 (1) Å], resulting in layers parallel to the bc plane.
EFFECTS OF BUTYLATED HYDROXYANISOLE (BHA) AND BUTYLATED HYDROXYTOLUENE (BHT) ON GROWTH AND AFLATOXIN PRODUCTION OF <i>ASPERGILLUS FLAVUS</i> (1977)

Butylated hydroxyanisole (BHA) and butylated hydroxytoluene (BHT) were applied to six strains of toxigenic and six strains of non‐toxigenic Aspergillus flavus in a method similar to antibiotic susceptibility testing. The cultures were examined for growth inhibition, spore formation, pigmentation, and aflatoxin production. BHA (0.005–0.020 g per plate) had an inhibitory effect on growth and toxigenesis of the test organisms, while BHT (0.005–0.020 g per plate) had no visible inhibitory effects. Sporulation of the cultures had no direct relationship with toxigenesis in the presence of BHA. However, pigmentation of the mycelium is directly related to the intensity of fluorescence of the culture under UV. Heating of BHA did not reduce the inhibitory effect of the compound on A. flavus.
A 0.36V, 33.3µW 18-band ANSI S1.11 1/3-octave filter bank for digital hearing aids in 40nm CMOS (2013)

This paper presents an ultra-low-power filter bank design for digital hearing aids. A novel time borrow & local boost (TBLB) scheme for aggressive voltage over-scaling is proposed, which does not incur cycle penalty on the rescue of timing violations, and is thus suitable for hardwired ASIC. The measured power of the test chips with the straightforward filter implementation can outperform those with extensive algorithmic or numerical optimizations.
Changes in the Concentration and Composition of Human Brain Gangliosides with Aging (1983)

Ganglioside content and composition were studied in whole brains from 9 neurologically normal male individuals ranging from 25 to 85 years in age. The content of ganglioside-bound sialic acid decreased from 1,070 to 380 micrograms/g fresh tissue at 85 years. Ten individual ganglioside fractions were identified on high-performance thin-layer chromatography, seven of which were quantified. With age, ganglioside composition shifted to a more polar pattern due to an increase in the relative concentration of the more polar fractions GQ1b, GT1b and GD1b and a decrease in GD1a and GM1. Except for GQ1b, the absolute concentration of all gangliosides decreased with age. All changes were more pronounced in younger ages. Results are discussed in relation to structural changes occurring in the aging brain, and the involvement of gangliosides is suggested.
A framework for the automated drawing of data structure diagrams (1990)

Data structure diagrams are two-dimensional figures made up of lines that aim to pictorially indicate the interrelationships of the elements of a data structure. The various rules and factors of aesthetics that go into the way data structure diagrams are drawn are collected together. The various subjective factors are formulated into computable objectives and numeric parameters. These are distilled from a large number of data structure drawings found in various textbooks. The rules used have not reached a level of acceptance comparable to that of the relevant rules in engineering graphics. The internal architecture of a (sub)system that helps draw data structure diagrams is outlined.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>