gebhart/patrepeval huggingface dataset:
Automatic generation of performance models for distributed application systems. (1998)

Organizations have become increasingly dependent on computing systems to achieve their business goals. The performance of these systems in terms of response times and cost has a major impact on their effectiveness. To achieve openness and scalability, these systems have begun to rely on distributed environment technologies such as the Open Software Foundation's Distributed Computing Environment (DCE) and the Object Management Group's Common Object Request Broker Architecture (CORBA). The resulting systems are complex and have performance behaviour that can defy intuition. Predictive performance models and performance evaluation techniques are needed to help manage their behaviour. Predictive models allow the timely evaluation of the performance impact of many different application loads and alternative configurations. Unfortunately model building by hand can be time- consuming and error-prone. This paper describes techniques developed to help automate the construction of performance models for operational distributed application systems. It describes the information that is needed to automate model building, the infrastructure that supports the model building, and the methods used to obtain or estimate the required information. An example is given to illustrate the model-building process and the evaluation of several what-if scenarios for management that can be answered using the model.
Impact of Sodium and Sulfur Species on Agglomeration and Defluidization during Spouted Bed Gasification of South Australian Lignite (2015)

Transformations of inorganic elements during steam gasification of a high-sodium, high-sulfur lignite were investigated in a 77 mm i.d. spouted bed reactor. The role of sodium and sulfur in agglomeration and defluidization of the bed material is assessed by analysis of inorganics in the bed char, in cyclone dust, in any agglomerates formed, and in deposits formed at the gas inlet to the reactor. It was found that a sodium disilicate-quartz eutectic was the key species in causing stickiness of the surface of mineral particles within the coal. The present data indicate that sodium and silica from the coal are reacting to form sodium silicate species, which forms the “glue” causing solid ash particles to cohere, initiating particle growth and agglomeration. This finding agrees with a fundamental study conducted by other authors. Sodium–calcium–sulfur eutectics, which have been found by other authors to cause agglomeration for similar coals under combustion conditions in a fluidized bed, were only found to form near the steam–air inlet to the reactor and thus do not play a significant part in agglomerate chemistry under the reducing conditions which exist throughout the majority of the bed under gasification conditions.
Immunochemical Studies with Tomato Leaf Proteins (1958)

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Molecular Dynamics Simulation of Supercritical Spray Phenomena (2008)

Abstract : Results showed that the way the fluid-wall interaction is modeled in molecular dynamics simulations has a strong effect on the resultant simulation of liquid injection into a gas. It was found that modeling the wall as individual atoms (atomistic model) interacting with the fluid resulted in the fluid remaining in an injection tube absent any pressure or body force to force it into a gaseous region while a stochastically modeled diffusely reflecting wall with no attraction between the fluid and the wall resulted in the fluid being injected into the gas even in the absence of pressure or body forces. Since a non-atomistically modeled wall has reduced computational requirements compared to an atomistic wall, efforts centered on an examination of possible non-atomistic continuous fluid-wall interaction models that would not only correctly reproduce fluid thermodynamic properties such as pressure but would also reproduce the same fluid injection behavior as an atomistic wall model. Several non-atomistic fluid-wall models were examined in terms of their ability to correctly predict the fluid pressure in the injection tube over a range of fluid densities as well as their ability to reproduce atomistic wall injection behavior, but none were found able to reproduce atomistic wall behavior.
Hypervelocity Impact with Flow and Shock Penetration Through Fluid, Plastic, and Elastic Zones. (1967)

Density 2.0 gm/cc,Impacti~g at 7.5 km/sec..
A General Synthetic Strategy for Oxide-Supported Metal Nanoparticle Catalysts (2006)

Despite recent exciting progress in catalysis by supported gold nanoparticles, there remains the formidable challenge of preparing supported gold catalysts that collectively incorporate precise control over factors such as size and size-distribution of the gold nanoparticles, homogeneous dispersion of the particles on the support, and the ability to utilize a wide range of supports that profoundly affect catalytic performance. Here, we describe a synthetic methodology that achieves these goals. In this strategy, weak interface interactions evenly deposit presynthesized organic-capped metal nanoparticles on oxide supports. The homogeneous dispersion of nanoparticles on oxides is then locked in place, without aggregation, through careful calcination. The approach takes advantage of recent advances in the synthesis of metal and oxide nanomaterials and helps to bring together these two classes of materials for catalysis applications. An important feature is that the strategy allows metal nanoparticles to be well dispersed on a variety of oxides with few restrictions on their physical and chemical properties. Following this synthetic procedure, we have successfully developed efficient gold catalysts for green chemistry processes, such as the production of ethyl acetate from the selective oxidation of ethanol by oxygen at 100 degrees C.
A design method for a fault-tolerant multi-agent stabilizing system for DC microgrids with Constant Power Loads (2012)

It is known that DC-power systems containing Constant Power Loads (CPLs) could become unstable under some conditions. This instability phenomenon is due to the interaction between the network structure and the negative impedance created by the CPLs. To ensure the system stability, we propose in this paper a method which permits to design a fault-tolerant stabilizing system for a DC-microgrid with CPLs. First, it consists in the implementation of local stabilizing agents on the CPLs. Then, using a constrained optimization problem, a method to design the stabilizing system is proposed. It permits to consider many fault cases as system reconfiguration or agent failure. To illustrate the method, it is implemented on test bench and experimental results are given to confirm its efficacy.
<scp>n</scp>-3 Polyunsaturated fatty acids prevent the defect of insulin receptor signaling in muscle (2002)

A high-fat diet containing polyunsaturated fatty acids (PUFA: n-3 or n-6) given for 4 wk to 5-wk-old male Wistar rats induced a clear hyperglycemia (10.4 ± 0.001 mmol/l for n-6 rats and 10.1 ± 0.001 for n-3 rats) and hyperinsulinemia (6.6 ± 0.8 ng/ml for n-6 rats and 6.4 ± 1.3 for n-3 rats), signs of insulin resistance. In liver, both diets (n-3 and n-6) significantly reduced insulin receptor (IR) number, IR and IR substrate (IRS)-1 tyrosine phosphorylation, and phosphatidylinositol (PI) 3′-kinase activity. In contrast, in leg muscle, IR density, as determined by Western blotting, was not affected, whereas IR and IRS-1 tyrosine phosphorylation in response to insulin treatment was restored in animals fed with n-3 PUFA to normal; in n-6 PUFA, the phosphorylation was depressed, as evidenced by Western blot analysis using specific antibodies. In addition, PI 3′-kinase activity and GLUT-4 content in muscle were maintained at normal levels in rats fed with n-3 PUFA compared with rats fed a normal diet. In rats fed with n-6 PUFA, both PI 3′-kinase activity and GLUT-4 content were reduced. Furthermore, in adipose tissue and using RT-PCR, we show that both n-3 and n-6 PUFA led to slight or strong reductions in p85 expression, respectively, whereas GLUT-4 and leptin expression was depressed in n-6 rats. The expression was not affected in n-3 rats compared with control rats. In conclusion, a high-fat diet enriched in n-3 fatty acids maintained IR, IRS-1 tyrosine phosphorylation, and PI 3′-kinase activity and total GLUT-44 content in muscle but not in liver. A high-fat diet (n-3) partially altered the expression of p85 but not that of GLUT-4 and leptin mRNAs in adipose tissue.
Carcinoid of the ampulla of vater. Local resection or pancreaticoduodenectomy (1993)

Long-term survival is possible after local excision or pancreaticoduodenectomy.
Scintigraphic localization of ovarian dysfunction. (1988)

To assess the potential role of scintigraphy in the evaluation of clinically and biochemically suspect ovarian hyperandrogenism (HA), dexamethasone suppression 131I-6 beta-iodomethyl-19-norcholesterol (NP-59) scans were performed to characterize ovarian function in nine patients. Pelvic ultrasound and/or computed tomography (CT) identified anatomic abnormalities in the adnexal region in six women in whom there was discernible pelvic accumulation(s) of NP-59. In the remaining three patients testosterone levels were normal or only slightly elevated and the NP-59 scan did not demonstrate abnormal adrenal or pelvic uptake. CT and/or ultrasound studies failed to demonstrate an abnormality in the pelvis suggesting excessive peripheral conversion or abnormal end organ sensitivity of androgen precursors as potential etiologies of their HA. In three women with androgen secreting lipoid tumors of the ovary, unilateral, pelvic NP-59 activity was noted; these tumors were subsequently resected. Two women with bilateral pelvic NP-59 uptake were later shown to have hyperthecosis with markedly asymmetric and enlarged ovaries. In one woman the extent of asymmetric NP-59 uptake was anticipated by the asymmetry of ovarian vein androgen levels at selective venous catheterization. In another woman with markedly asymmetric polycystic ovary disease, intense focal uptake of NP-59 localized to the side of the anatomically abnormal, enlarged ovary. Thus, our preliminary study reviews our experience to date and suggests that NP-59 scintigraphy may be used to localize both tumorous and nontumorous ovarian dysfunction in states of HA and virilization.
BAFF Induces Tertiary Lymphoid Structures and Positions T Cells within the Glomeruli during Lupus Nephritis (2017)

Tissue-specific immune responses play an important role in the pathology of autoimmune diseases. In systemic lupus erythematosus, deposits of IgG-immune complexes and the activation of complement in the kidney have long been thought to promote inflammation and lupus nephritis. However, the events that localize cells in non-lymphoid tertiary organs and sustain tissue-specific immune responses remain undefined. In this manuscript, we show that BAFF promotes events leading to lupus nephritis. Using an inducible model of systemic lupus erythematosus, we found that passive transfer of antinucleosome IgG into AID<sup>-/-</sup>MRL/lpr mice elevated autoantibody levels and promoted lupus nephritis by inducing BAFF production in the kidneys, and the formation of renal tertiary lymphoid structures (TLSs). Reducing BAFF in vivo prevented the formation of TLSs and lupus nephritis; however, it did not reduce immune cell infiltrates, or the deposits of IgG and complement in the kidney. Mechanistically, lowering BAFF levels also diminished the number of T cells positioned inside the glomeruli and reduced inflammation. Thus, BAFF plays a previously unappreciated role in lupus nephritis by inducing renal TLSs and regulating the position of T cells within the glomeruli.
Soil–Ice Behavior in a Model Retaining Structure (1971)

Experimental creep data on model cylindrical retaining structures formed from two frozen soils, saturated Ottawa sand and Ontonagon (Sault Ste. Marie) clay, are presented. The sand–ice behavior in the model barrier is analyzed using a constitutive relationship which includes the state of stress, state of strain, time, and temperature. Displacement rates at the inner wall surface calculated according to the creep relationship agree with measured rates for properly chosen values of a parameter which modifies the contribution of the deviatoric stress component to the creep rate.The axial force observed at the sample ends provided information as to the soil–ice behavior during primary and secondary creep. For the sand–ice material this axial force did not reach its final value until steady-state creep was approximated. This indicates that Poisson's ratio may change depending on the stage or development of the creep deformations. This behavior was not observed for the frozen clay. The stress – strain – time behavior for the two soils differed considerably due to the greater amounts of unfrozen water in the frozen clay (about 50 %) as compared with the saturated Ottawa sand (little or none).
Fracture of a Retention Wire in an Atrial <i>J</i> Pacemaker Lead (1996)

Figure 1. A fracture of a retention wire in an atrial J pacemaker lead (model 330-801, Telectronics, Englewood, Colo.) was detected by chest radiography. The wire, which maintains the J shape of the lead, had fractured, and the distal fragment had migrated from the lead body. Both fragments, visible on the initial chest x-ray film taken at an oblique angle (Panel A, arrows), became more apparent when the image was enlarged (Panel B, arrows).
New Aliphatic Alcohol and (Z)-4-Coumaric Acid Glycosides from Acanthus ilicifolius (2003)

From the aerial parts of Acanthus ilicifolius, a new aliphatic alcohol glycoside (ilicifolioside C) and two new (Z)-4-coumaric acid glycosides, (Z)-4-coumaric acid 4-O-beta-D-glucopyranoside and (Z)-4-coumaric acid 4-O-beta-D-apiofuranosyl-(1"-->2')-O-beta-D-glucopyranoside were isolated. The structural elucidations were based on the analyses of spectroscopic data. Z-Form 4-coumaric acid glycosides were first isolated from plant.
Preliminary neuropsychological findings in individuals at high genetic risk for schizophrenia (2008)

These findings support the hypothesis that a common cognitive pattern exists across individuals with genetic risk that may later develop into a clear psychotic illness. Further longitudinal investigation with larger cohorts is crucial to understanding these findings.
Guidelines for establishing locus specific databases (2011)

Information about genetic variation has been collected for some 20 years into registries, known as locus specific databases (LSDBs), which nowadays often contain information in addition to the actual genetic variation. Several issues have to be taken into account when considering establishing and maintaining LSDBs and these have been discussed previously in a number of articles describing guidelines and recommendations. This information is widely scattered and, for a newcomer, it would be difficult to obtain the latest information and guidance. Here, a sequence of steps essential for establishing an LSDB is discussed together with guidelines for each step. Curators need to collect information from various sources, code it in systematic way, and distribute to the research and clinical communities. In doing this, ethical issues have to be taken into account. To facilitate integration of information to, for example, analyze genotype-phenotype correlations, systematic data representation using established nomenclatures, data models, and ontologies is essential. LSDB curation and maintenance comprises a number of tasks that can be managed by following logical steps. These resources are becoming ever more important and new curators are essential to ensure that we will have expertly curated databases for all disease-related genes in the near future.
Polarization singularities in the self-focusing of an elliptically polarized laser beam in an isotropic phase of cholesteric liquid crystal close to the temperature of phase transition (2020)

The work is devoted to the self-action of laser beams propagating in the isotropic phase of a cholesteric liquid crystal near the transition temperature to the mesophase in a wide range of parameter values characterizing the nonlocality of the nonlinear optical response of the medium, defocusing in the medium, the power of incident laser radiation and diffraction in the liquid crystal. The origin of the primary singularities of both polarization components of radiation in a wide range of parameters of radiation and the medium is investigated for different values of the parameter characterizing the nonlocality of nonlinear optical response in chiral medium. For each of the values, the visibility diagrams of the primary singularities of both polarization components are plotted depending on the parameters of the medium and radiation, and their asymmetry is found.
Original superconducting quantum interference device (SQUID) design and measurement technique for flux noise source localization in SQUID systems (2003)

We present an original method for studying the low frequency flux noise due to vortices in superconducting quantum interference device (SQUID) systems. We use two SQUIDs connected to the same washer in order to study the correlation of their outputs. A dedicated electronic system has been built so as to operate both SQUIDs at the same time. It was thus possible to distinguish fluctuations due to vortices located in the film far from the SQUID from fluctuations originating from vortices located close to the SQUID itself. In this article, the experimental setup is described and some preliminary noise measurements are presented.
Modeling of overhead transmission lines with segmented shield wires for signal attenuation calculation in power line carrier systems (2011)

This paper presents modeling methods for overhead transmission lines with segmented shield wires, as well as signal attenuation calculation for different coupling methods for use in power line carrier (PLC) systems. The purpose of this paper is to present a generalized method to model transmission lines with segmented shield wires, along with steps for signal attenuation calculation in the phase domain for different PLC coupling methods. Electromagnetic Transients Program (EMTP) simulation results for signal attenuation are provided for comparison with the generalized model calculation results.
The subcutaneous adipose tissue reservoir of functionally active stem cells is reduced in obese patients (2012)

It has been demonstrated that the adipose tissue, a highly functional metabolic tissue, is a reservoir of mesenchymal stem cells. The potential use of adipose-derived stem cells (ADSCs) from white adipose tissue (WAT) for organ repair and regeneration has been considered because of their obvious benefits in terms of accessibility and quantity of available sample. However, the functional capability of ADSCs from subjects with different adiposity has not been investigated. It has been our hypothesis that ADSCs from adipose tissue of patients with metabolic syndrome and high adiposity may be functionally impaired. We report that subcutaneous WAT stromal vascular fraction (SVF) from nonobese individuals had a significantly higher number of CD90+ cells than SVF from obese patients. The isolated ADSCs from WAT of obese patients had reduced differentiation potential and were less proangiogenic. Therefore, ADSCs in adipose tissue of obese patients have lower capacity for spontaneous or therapeutic repair than ADSCs from nonobese metabolically normal individuals.
A11990 Long-Term Exposure of PM2.5 Causes Hypertension by Impaired Renal D1 Receptor Mediated Sodium Excretion via Up-regulation of GRK4 Expression in SD rats (2018)

Objectives: Epidemiological evidence supports an important association between air pollution exposure and hypertension. However, the mechanisms are not clear. Methods: Na+-K+ ATPase activity, D1 receptor expression and phosphorylation and GRK4 expression were measured in renal proximal tubule (RPT) cells. Also, plasma reactive oxygen species (ROS), blood pressure and sodium excretion were tested in SD rats treated with or without PM2.5. Results: As we know that long-term exposure to PM2.5 causes hypertension and impairs renal sodium excretion due to lower D1 receptor expression and higher D1 receptor phosphorylation, accompanied with a higher GRK4 expression. PM2.5 increased basal and decreased D1 receptor mediated inhibitory effect on Na+-K+ ATPase activity, decreased D1 receptor expression and increased D1 receptor phosphorylation in RPT cells. The downregulation of D1 receptor expression and function might be due to a higher GRK4 expression after the exposure of RPT cells to PM2.5, since down-regulation of GRK4 by siRNA reversed the D1 receptor expression and function. Due to the role of ROS on D1 receptor dysfunction and its relationship with air pollution exposure, we determined plasma ROS, and found the levels higher in PM2.5 treated SD rats. Inhibition of ROS by tempol reduced blood pressure and increased sodium excretion in PM2.5 treated SD rats, accompanied by an increase in the low D1 receptor expression, and decreased the hyperphosphorylated D1 receptor and GRK4 expression. Conclusion: Our present study indicated that long-term exposure of PM2.5 increases blood pressure by decreasing D1 receptor expression and function; ROS, via regulation of GRK4 expression, plays an important role in the pathogenesis of PM2.5-induced hypertension.
BDD Based Synthesis of Symmetric Functions with Full Path-Delay Fault Testability. (2003)

A new technique for synthesizing totally symmetric Boolean functions is presented that achieves complete robust path delay fault testability. We apply BDDs for the synthesis of symmetric functions. Only one additional input and one inverter are needed to achieve 100% Path Delay Fault (PDF) testability. The size of the circuit is guaranteed to be at most quadratic in the number of inputs. The test vectors for any PDF can be generated in linear time. Experimental results underline the efficiency of the approach. In contrast to previous approaches, the technique can also be applied to multi-output functions.
ChemInform Abstract: 1,3‐Dipolar Cycloaddition of 2‐Diazoalkanes to Pyridazin‐3(2H)‐one Derivatives. The Formation of 3H‐Pyrazolo(3,4‐d)pyridazin‐4(5H)‐one and 3H‐Pyrazolo(3,4‐d)pyridazin‐7(6H)‐one Derivatives. (1991)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Optical properties and stress of ion-assisted aluminum nitride thin films (1992)

The optical properties and stress in thin films of aluminum nitride have been studied as a function of ion energy and the ion-to-vapor arrival ratio (J(i)/J(v)) for the N(2)(+) ion-assisted deposition of aluminum. The ion energy was varied between 75 and 1000 eV. The refractive index was found to depend on the ion energy and flux. The highest index was 2.10 at 633 nm. The films were found to be highly transparent over the wavelength region 275-800 nm. The films were found to be free of major oxide contamination, and x-ray photoelectron spectroscopy studies revealed the presence of excess nitrogen in films prepared at high J(i)/J(v) values. The film stress was also found to be related to the ion energy, and an anomalously high compressive stress of -5.0 GPa was found for 100-eV N(2)(+)-assisted depositions. By comparison, films prepared by magnetron deposition were found to have lower refractive indices (1.97-1 99, n633) and higher stress (-8 to -12 GPa) when deposited in pure nitrogen.