gebhart/patrepeval huggingface dataset:
The problem of proprietary dyes, with special reference to alamar blue, a proprietary dye revealed (2001)

No abstract available.
The changing professional practice of physician assistants: 1992 to 2000. (2004)

Enabling legislation for PAs has been enacted in all 50 states and the District of Columbia over a 3-decade period. A period of consolidation and convergence of statutes and policies over the 1990s suggests that American medicine has endorsed the role of PAs. In spite of these findings, almost one third of states continue to have limited or restricted statutes for PA practice, mostly in the area of reimbursement.
Simulation of the Alcohol-Slug Process Using the "Cell Model" (1964)

Abstract The similarity of the mechanism of miscible displacement to the functioning of packed columns has led to suggestions that the "theoretical plate" concept might be a useful mathematical model for the simulation of miscible displacement processes. Such a model would rest on the assumption that the porespace of a linear porous medium is equivalent to a certain number of "plates"or cells and that, in each cell, only a fraction of the fluid volume ismovable. During displacement, the movable volume from each cell moves on toeach succeeding cell, establishing equilibria with the respective stationary volumes. When two phases are present in the model, relative phase mobilities, as governed by viscosities and phase saturations, will affect the movable fractionin each cell. If, in addition, there is interphase transfer of material, the equilibrium condition for each cell is governed by the amounts and mutual solubilities of the components. While the procedure is quite general, thepresent study is confined to various ternary water-hydrocarbon-alcohol systems.To expedite computations, general mathematical relations were developed for thebinodal curves and tie lines. These were necessary to obtain the phase volumes and compositions for any over-all cell composition. Expressions for phasemobility ratios as functions of saturations were also used. The validity of the model has been demonstrated by comparisons of efflux histories for alcohol displacements of oil and water as obtained from the model and from laboratory experiments. Introduction It has been known for some time that a sufficient volume of certain lower alcohols will effectively displace all or most of the oil and water contacted in an oil-water porous medium system. As alcohols are considerably more expensive than equal volumes of recovered oil, an economically successful process requires that only a finite volume or slug of alcohol displace the oil and water.
[Autonomic nervous system adaptation during physical exercise]. (2001)

Physical exercise is a physiologic condition in which a variety of mechanisms and production/control systems combine and interact in order to accomplish the desired task (physical exercise) and preserve and/or restore body homeostasis. The autonomic nervous system provides a double response during exercise: at first a prevailing parasympathetic withdrawal followed, with the increase in duration and intensity of exercise, by a prevailing sympathetic activation. These modifications interact with the regulation of breathing, of body temperature, and of oxygen transport from the lungs to the body tissues through the modulation of the cardiac pump function and of the systemic and local vasoactivity and, at a tissue level, through the modulation of the local metabolism and the production of vasoactive and chemoactive substances. In the present review these aspects and the effects of physical training on the autonomic nervous system are examined in normal subjects and in patients with heart failure.
Gangrene of the Hand Following Intra-arterial Injection (1967)

THE INTRA-ARTERIAL injection of medications in the upper limb may result in serious impairment or loss of part of the extremity. When one reflects on the frequency and casualness with which medications are injected intravascularly into various parts of the upper limb, it is remarkable that there should be so few untoward incidents reported. The textbooks of pharmacology and anesthesiology comment to a varying degree on the complications associated with the intra-arterial injection of drugs. With the exception of thiopental sodium<sup>1-7</sup>and contrast media, there is little in the medical journals concerning these complications. A number of other compounds have been incriminated; for example, promazine HCl,<sup>8</sup>chlorpromazine HCl,<sup>9</sup>ether,<sup>10</sup>and mephenesin (Myanesin).<sup>11</sup>A number of reports attribute arterial thrombosis and gangrene to idiosyncrasy or local irritation.<sup>8,9,12,13</sup>It is more likely that these cases reflect the intraarterial injection of the drug. Reported here are three
Tip-Enhanced Raman Spectroscopy: Near-Fields Acting on a Few Molecules (2012)

Tip-enhanced Raman spectroscopy (TERS) is a very powerful variant of surface-enhanced Raman spectroscopy (SERS). In a sense, TERS overcomes most of the drawbacks of SERS but keeps its advantages, such as its high sensitivity. TERS offers the additional advantages of high spatial resolution, much beyond the Abbe limit, and the possibility to correlate TER and other scanning probe microscope images, i.e., to correlate topographic and chemical data. TERS finds application in a number of fields, such as surface science, material science, and biology. Single-molecule TERS has been observed even for TERS enhancements of "only" 10(6)-10(7). In this review, TERS enhancements are discussed in some detail, including a condensed overview of measured contrasts and estimated total enhancements. Finally, recent developments for TERS under ultrahigh vacuum conditions are presented, including TERS on a C(60) island with a diameter of a few tens of nanometers, deposited on a smooth Au(111) surface.
When birth comes early: Effects on nephrogenesis (2012)

Preterm birth (birth prior to 37 completed weeks of gestation) may occur at a time when the infant kidney is very immature and nephrogenesis is often ongoing. In autopsied preterm human kidneys and in a baboon model of preterm birth it has been shown that nephrogenesis continues after preterm birth, with a significant increase in the number of glomerular generations and number of nephrons formed within the kidney after birth. Of concern, however, morphologically abnormal glomeruli (with a cystic Bowman's space) are often observed; the abnormal glomeruli are only located in the outer renal cortex, suggesting that it is the recently formed glomeruli (perhaps those formed in the extra-uterine environment) that are affected. The proportion of abnormal glomeruli within the renal cortex differs between infants with some kidneys appearing normal whereas others are severely affected. This suggests that it may be haemodynamic factors and/or factors in the neonatal care of the infant that lead to the glomerular abnormalities. Indeed, the haemodynamic transition at birth where there is a marked increase in systemic blood pressure and renal blood flow are likely to lead to injury of glomerular capillaries, although further studies are required to elucidate this. In order to optimize renal health at the beginning of life in the preterm infant, it is imperative in future studies to gain an understanding of the causes of the glomerular abnormalities in the preterm neonate.
Structural Crashworthiness and Failure (1993)

Abstract : Failure in ductile material using finite element methods; modelling the process of failure in structures; criteria for the inelastic rupture of ductile metal beams subjected to large dynamic loads; strain localisation and fracture in metal sheets and thin walled structures; impact on metal tubes; indentation and perforation; composite strength and energy adsorption as an aspect of structural crash resistance; crash response of composite structures; dynamic compression of cellular structures and materials; elastic effects in the dynamic plastic response of structure; impact performance of aluminium structures, motorway impact attenuation devices: past, present and future; and grounding damage of ships
Novel preparation protocol for the expression and purification of recombinant staphylokinase (2008)

Staphylokinase (Sak), produced by lysogenic strains of Staphylococcus aureus, can convert plasminogen into its proteolytic form, plasmin, and thus is widely used to dissolve pathological clots in clinical applications. In the present paper, we report a novel approach to produce r-Sak (recombinant Sak) using an engineered Escherichia coli expression system. The expression plasmid was constructed by placing the Sak gene into the expression vector pET32(a), resulting in the expression of 35% fusion protein. Subsequently, a rapid and simple chromatographic procedure was developed for the large-scale purification of therapeutic-grade r-Sak from E. coli, which includes Ni(2+)-affinity chromatography, ultrafiltration and Q-Sepharose Fast Flow chromatography. This method led to the production of highly pure r-Sak (>99%), according to SDS/PAGE and HPLC analysis.
Ocular surface diseases and corneal refractive surgery (2014)

By understanding the mechanisms of postoperative dry eye as well as patient risk factors for dry eye, patient satisfaction and surgical outcomes can be maximized. Patients identified as having an increased risk for postoperative dry eye may benefit from surgical techniques such as small-incision lenticule extraction (SMILE) and femtosecond laser-assisted in-situ keratomileusis (LASIK). Employing well known therapies such as preserved and nonpreserved artificial tears, nutritional supplements, topical cyclosporins, punctal plugs and autologus serum as well as novel therapies such as insulin-like growth factor 1, neuropeptides and acupuncture could provide improve outcomes and, if started early, could allow more patients to be candidates for corneal refractive surgery.
Nbs1 potentiates ATP-driven DNA unwinding and endonuclease cleavage by the Mre11/Rad50 complex (1999)

The Nijmegen breakage syndrome gene product (Nbs1) was shown recently to associate in vivo with the Mre11 and Rad50 proteins, which play pivotal roles in eukaryotic DNA double-strand break repair, meiotic recombination, and telomere maintenance. We show in this work that the triple complex of recombinant Nbs1, Mre11, and Rad50 proteins binds cooperatively to DNA and forms a distinct protein-DNA species. The Mre11/Rad50/Nbs1 complex displays several enzymatic activities that are not seen without Nbs1, including partial unwinding of a DNA duplex and efficient cleavage of fully paired hairpins. Unwinding and hairpin cleavage are both increased by the presence of ATP. On nonhairpin DNA ends, ATP controls a switch in endonuclease specificity that allows Mre11/Rad50/Nbs1 to cleave a 3'-protruding strand at a double-/single-strand transition. Mutational analysis demonstrates that Rad50 is responsible for ATP binding by the complex, but the ATP-dependent activities are expressed only with Nbs1 present.
Concrete Strength in Structures (1968)

First Name is required invalid characters Last Name is required invalid characters Email Address is required Invalid Email Address Invalid Email Address
Investigating the Validity of Acoustic Spectrum as a Prediction Tool for Pump Cavitation (2015)

Cavitation in pumps causes destructive consequences; it must be detected and prevented. The aim of the present work is investigating the validity of sound spectrum as a prediction tool for pump cavitation. Results showed that; for the discrete frequencies of RF = 47.5 Hz, and BPF = 285 Hz and its second, third, and fourth harmonics of 570 Hz, 855 Hz, and 1140 Hz respectively; there are no great variations in the noise signal for the cavitation and non-cavitation conditions. For the discrete frequency of 147 Hz, there is also no great variation in the noise signal at this frequency. The only apparent result is that; the occurrence of cavitation results high energy noise signals at high frequencies from 1000 Hz to 10000 Hz. The absence of any discrete frequency to be monitored makes the sound spectrum not valid as a prediction tool for cavitation in the pumps.
Combining Spatial and Temporal Information for Gait Based Gender Classification (2010)

In this paper, we address the problem of gait based gender classification. The Gabor feature which is a new attempt for gait analysis, not only improves the robustness to the segmental noise, but also provides a feasible way to purge the additional influence factors like clothing and carrying condition changes before supervised learning. Furthermore, through the agency of Maximization of Mutual Information (MMI), the low dimensional discriminative representation is obtained as the Gabor-MMI feature. After that, gender related Gaussian Mixture Model-Hidden Markov Models (GMM-HMMs) are constructed for classification work. In this case, supervised learning reduces the dimension of parameter space, and significantly increases the gap between likelihoods of the gender models. In order to assess the performance of our proposed approach, we compare it with other methods on the standard CASIA Gait Databases (Dataset B). Experimental results demonstrate that our approach achieves better Correct Classification Rate (CCR) than the state of the art methods.
IV. ’Aμóρϕωτa, no. I.— on a case of superficial colour presented by a homogeneous liquid internally colourless (1845)

Abstract A certain variety of fluor spar, of a green colour, from Alston Moor, is well known to mineralogists by its curious property of exhibiting a superficial colour, differing much from its transmitted tint, being a fine blue of a peculiar and delicate aspect like the bloom on a plum, and like that bloom might perhaps be referred to a peculiar texture of the surface, the result of crystallization, were it not that it appears equally on a surface artificially cut and polished. Glasses also are manufactured which, by the agency of a delicate superficial film, consisting apparently of a dull green-coloured powder, and reflecting (or rather dispersing) a green light, exhibit a brownish red tint by transmission; chloride of sulphur, and the infusion of lignum nephriticum are particularized in some books as exhibiting different colours by transmitted and reflected light. As respects the chloride of sulphur, the statement is incorrect, and has originated in a misapprehension of its scale of absorbent action, which (as is the case with many dichromatic media) causes its hue to change from green to red by mere increase of thickness. In the infusion of lignum nephriticum, and in one other instance which has occurred to my notice, the reflected tint arises from suspended particles too minute, or too nearly of the specific gravity of the liquid, to be separated by subidence,the transmitted colour being that of the transparent liquid in which they float, and the particles themselves being opake. The case which I am about to describe is not precisely parallel to any of these, though far more striking than either. That of the fluor spar presents the closest analogy to it, though from what we know of the impracticability of obliterating the internal structure of mother-of-pearl by any artificial polish, the difference between the solid and fluid states of aggregation precludes any argument from that phenomenon to the one in question.
소셜 미디어와 학생의 도덕 발달 (2020)

윤리학과 도덕교육에서 지배적인 관점은 소셜 미디어 사용의 부정적 측면만을 강조할 뿐, 소셜 미디어의 전략적 사용을 통한 자기실현이나 사회 발전에의 기여와 같은 긍정적 측면을 상당히 무시했던 것이 사실이다. 또한, 우리는 소셜 미디어가 학생의 도덕 발달에 미치는 영향에 관한 세심한 분석은 생략한 채, 안전하고 책임 있고 윤리적인 사용만을 일방적으로 강조하여 왔다. 기존의 소셜 미디어 연구 문헌에서도 학생의 도덕 발달과 관련한 소셜 미디어의 잠재적인 영향에 대한 체계적인 분석은 매우 소홀하였다. 하지만, 소셜 미디어가 인지 기능, 공감 능력, 정체성, 나르시시즘, 시민 참여 등에 미치는 영향을 고려할 때, 우리는 소셜 미디어가 학생의 도덕 발달에 미치는 잠재력을 어느 정도 추론할 수 있다. 이에 이 논문에서는 소셜 미디어가 학생의 도덕 발달에 미치는 잠재적인 영향력을 문헌 분석을 통해 살펴보았다. 이 논문은 소셜 미디어가 학생의 도덕 발달에 미치는 영향을 도덕성의 3가지 구성 요소에 해당하는 도덕 인지, 도덕 정서, 도덕 행동의 측면에서 살펴보았다. 끝으로, 이 논문은 도덕교육의 새로운 어휘로서 디지털 시민성(digital citizenship)의 중요성을 제안하는 가운데, 소셜 미디어 관련 정책에서 보호/관리 패러다임과 육성/진흥 패러다임이 적절한 균형을 이루어야 한다는 사실을 강조하였다.
Limitation in the detection of Listeria monocytogenes in food in the presence of competing Listeria innocua (2007)

After the enrichment, the PCR detection is more convenient than the standard one as PCR detection is not compromised by other present microflora.
Use of Half-Normal Plots in Interpreting Factorial Two-Level Experiments (1959)

Plotting the empirical cumulative distribution of the usual set of orthogonal contrasts computed from a 2 p experiment on a special grid may aid in its criticism and interpretation. Bad values, heteroscedasticity, dependence of variance on mean, and some types of defective randomization, all leave characteristic stigmata. The halfnormal plot can be used to estimate the error standard deviation and to make judgments about the reality of the observed effects. An accompanying paper by A. Birnbaum gives some operating characteristics of these judgments. Examples are given of the use of half-normal plots in each of these ways.
The Frequency of Emotional and Behavioural Disturbance in an EBD School (2000)

The education of children with behavioural difficulties is under scrutiny from various quarters. The provision of specialised school environments is being questioned, at the same time as there is pressure to minimise the exclusion of disruptive pupils. This study looked at the rate of psychiatric disorder that was prevalent in a school for emotionally and behaviourally disordered (EBD) pupils, and found, using DSM III-R criteria, that 24% of the sample had depression, 11% had overanxiousness, and 70% had a diagnosis of Attention Deficit Disorder with Hyperactivity (ADHD). Educational attainment assessment showed that 75% had a reading age that was at least 2 years below their chronological age. These results suggest that such settings are dealing with a very disturbed group of youngsters.
Ultrasound-targeted microbubble destruction promotes proliferative vitreoretinopathy induced by RPE-J cells and platelet-rich plasma (2011)

Ultrasound-targeted microbubble destruction (UTMD) has been considered as a new approach to the gene therapy of proliferative vitreoretinopathy (PVR), but whether it affect the in vivo PVR model induction remains unknown. In this study, 90 Wistar rats were averagely divided into three groups according to the content of intravitreal injection: normal saline (Group 1), retinal pigmented epithelial -J cells and PRP (Groups 2 and 3). In Group 3, a condition of UTMD was used additionally on days 3 and 7 after injection. On days 14 and 28, the pathological changes of eye grounds were assessed, and the expression levels of transforming growth factor (TGF)-β2 and platelet-derived growth factor (PDGF)-BB were tested. In Group 3, proliferation in the eyes was significantly stronger and faster than that of Group 2 and the ratio of PVR was significantly higher than that of Group 2. The expression levels of TGF-β2 and PDGF-BB were significantly higher in Group 3 than in Group 2. These data suggested that UTMD promotes PVR induced by RPE-J cells and PRP which provide a new method for the development of rat PVR model. This also reminds us that the effects of UTMD should be taken into consideration when using UTMD as an approach to attenuate PVR.

	 

	Key words: Proliferative vitreoretinopathy, rat model, ultrasound-targeted microbubble destruction, retinal pigmented epithelial -J cells, platelet-rich plasma.
Congenital defects in newborn foals of mares treated for equine protozoal myeloencephalitis during pregnancy (1998)

Three weak, recumbent neonatal foals with skin lesions, including a thin wooly coat, were born to mares being treated for equine protozoal myeloencephalitis. Mares received sulfadiazine or sulfamethoxazole-trimethoprim, pyrimethamine, folic acid, and vitamin E orally. Foals were anemic, leukopenic, azotemic, hyponatremic, and hyperkalemic. Serum folate concentrations in the 3 foals and 2 mares were lower than those reported in the literature for clinically normal brood mares. Treatment was unsuccessful. For each foal, necropsy revealed lobulated kidneys with thin cortices and a pale medulla, and the spleen and thymus were small. Histologic examination revealed marked epidermal necrosis without inflammatory cells, thin renal cortices, renal tubular nephrosis, lymphoid aplasia, and bone marrow aplasia and hypoplasia. These observations indicate that oral administration of sulfonamides, 2,4-diaminopyrimidines (pyrimethamine with or without trimethoprim), and folic acid to mares during pregnancy is related to congenital defects in newborn foals.
Zeugen niet voor het eerst aanbinden in kraamstal (1989)

Zeugen, die in de kraamstal voor het eerst worden aangebonden werpen biggen die gemiddeld 50 gram lichter zijn.
Estimating the k-mer Coverage Frequencies in Genomic Datasets: A Comparative Assessment of the State-of-the-art (2018)

The results of this evaluation may serve as a roadmap to potential users and practitioners of streaming algorithms for estimating k-mer coverage frequencies, to assist them in identifying an appro-priate method. Such results analysis also help researchers to discover remaining open research ques-tions, effective combinations of existing techniques and possible avenues for future research.
Irreversible G2-M arrest and cytoskeletal reorganization induced by cytotoxic nucleoside analogues. (1998)

The mechanisms by which cytotoxic agents perturb the normal cell biology and cell cycle progression of cancer cells were explored using B16F10 cells genetically modified to express the Herpes Simplex Virus-thymidine kinase gene. Culture in the presence of the nucleoside analogue ganciclovir induced a profound morphological change that required entry of treated cells into S phase and was dependent on prenylated proteins such as those of the rho gene family. Cell cycle arrest occurred in late S phase or G2 phase due to the activation of the G2-M DNA damage checkpoint. This checkpoint control operated at the level of inhibition of the activity of Cdc2/cyclin B and occurred by two mechanisms: (a) p53-mediated up-regulation of p21CIP/WAF1 expression and its association with Cdc2/cyclin B; and (b) prevention of the dephosphorylation of tyrosine 15 of Cdc2. These events occurred in vitro and in vivo, and were shown to mediate bystander killing in this model. The mechanism of cell death seemed to be due to the irreversible cell cycle arrest at the G2-M checkpoint, rather than induction of apoptosis. These data link DNA damage checkpoints with cytoskeletal signaling pathways and the core cell cycle machinery and may represent a general mechanism of cytotoxicity of this class of nucleoside analogues.
Platform firmware resiliency guidelines (2018)

The Information Technology Laboratory (ITL) at the National Institute of Standards and Technology (NIST) promotes the U.S. economy and public welfare by providing technical leadership for the Nation's measurement and standards infrastructure. ITL develops tests, test methods, reference data, proof of concept implementations, and technical analyses to advance the development and productive use of information technology. ITL's
Milk and Tissue Lipid Composition After Feeding Cows Protected Polyunsaturated Fat for Two Years (1977)

The long-term effects of feeding Holstein cows plant lipids protected from microbial hydrogenation in the rumen were studied. Of particular interest were cow health and changes in fatty acid and cholesterol concentrations of milk and meat. Safflower oil-casein or safflower oil-casein treated with formaldehyde to impede microbial attack were fed to two groups of three cows as 10% of the concentrate ration for two lactations. Production of milk fat of cows fed the protected concentrate increased significantly. Linoleic acid of milk fat was twice normal, providing a polyunsaturated milk. Cholesterol of milk or meat did not increase even though cholesterol of blood plasma was higher in both groups fed safflower oil than in control cows. Cardiovascular systems showed no marked abnormalities and no differences that could be due to treatment. All cows maintained normal health and milk production throughout the experiment.