gebhart/patrepeval huggingface dataset:
Abstract 288: Secondary Prevention Following Coronary Artery Bypass Surgery: The Need For a Continuum of Care (2012)

Purpose: Sustained positive outcomes after coronary artery bypass grafting (CABG) requires risk factor modification and secondary prevention medications. This study assessed the influence of a multidisciplinary educational program on disease understanding, motivation to reduce cardiovascular risk, and secondary prevention medication prescribing following CABG. Methods: Using a prospective, randomized, controlled design, adults undergoing CABG completed surveys at discharge, 3 months, and 12 months, assessing disease understanding and motivation to reduce cardiovascular risk. Four to six weeks after CABG, intervention subjects completed an educational program involving group discussions and individual counseling with pharmacists, dietitians, and a cardiac rehabilitation nurses. The primary endpoint was a composite score of reduced risk factors, medication use among those eligible, and awareness of prescribed medications. Secondary endpoints evaluated survey scores and medication use rates. Wilcoxon Rank Sum and Chi Square tests compared data between specific time points. Generalized estimating equations and linear contrasts of the parameter estimates compared data at the three time points. Results: The final analysis included 98 subjects (I=49, C=49). The composite score was not different between groups (I=12.8±4.5 points, C=12.7±4.9 points, p=0.9405). Improvements were noted in understanding and motivation in the entire cohort, but these changes could not be attributed to our intervention. Medication use declined at 3 and 12 months after CABG without significant differences between the groups. Conclusions: Disease understanding, motivation to reduce risk, and medication use is robust at hospital discharge but declines with time and was not improved by our intervention. These findings are concerning and warrant further study.
Forward and Inverse Scattering of Surface Waves (2005)

A034 0-000 FORWARD AND INVERSE SCATTERING OF SURFACE WAVES Summary A. KASLILAR 1 C.D.RIYANTI 1 X.CAMPMAN 1 and G.C. HERMAN 2 1 Institute of Applied Mathematics Delft University of Technology P.O. Box 5031 2600 GA Delft The Netherlands. 2 Shell E&P The Netherlands. Surface waves can be used for imaging near surface layers since they are sensitive to near surface heterogeneities. We developed a method for imaging shallow subsurface heterogeneities and estimating their density contrast using scattered surface waves. We consider 3D elastodynamic scattering by heterogeneities in a laterally invariant layered embedding. We represent the scattered wavefield as a domain
Studies on Soybean Trypsin Inhibitors (1978)

Soybean inhibitor D-II is an inhibitor of bovine trypsin. Sequence analysis was carried out on the reduced and S-carboxymethylated protein by conventional methods to establish the complete amino acid sequence. The sequence of D-II indicated high homology with other legume inhibitors, but it was unique because of the occurrence of identical residues (arginine) at both of the reactive sites. This structure is thought to reflect that of a prototype double-headed inhibitor. The possible evolutionary process of the legume double-headed inhibitors is discussed on this basis. Comparison with another soybean inhibitor C-II suggested that a single methionine (C-II)-glutamine (D-II) replacement at the P2'position resulted in the loss of alpha-chymotrypsin inhibitory activity of D-II. The results of a hydrogen peroxide oxidation experiment on C-II supported this suggestion. The sequence of the amino-terminal 21 residues of inhibitor E-I was determined using a sequentor. It was shown that this inhibitor lacks the amino-terminal nine residues of D-II.
Clinical Features Observed in General Practice Associated With the Subsequent Diagnosis of Progressive Supranuclear Palsy (2021)

<b>Background:</b> Progressive supranuclear palsy (PSP) is a rare neurodegenerative disorder that is difficult for primary care physicians to recognize due to its progressive nature and similarities to other neurologic disorders. This case-control study aimed to identify clinical features observed in general practice associated with a subsequent diagnosis of PSP. <b>Methods:</b> We analyzed a de-identified dataset of 152 PSP cases and 3,122 matched controls from electronic medical records of general practices in Germany. We used a random forests algorithm based on machine learning techniques to identify clinical features (medical conditions and treatments received) associated with pre-diagnostic PSP without using an <i>a priori</i> hypothesis. We then assessed the relative effects of the features with the highest importance scores and generated multivariate models using clustered logistic regression analyses to identify a subset of clinical features associated with subsequent PSP diagnosis. <b>Results:</b> Using the random forests approach, we identified 21 clinical features associated with pre-diagnostic PSP (odds ratio ≥2.0 in univariate analyses). From these, we constructed a multivariate model comprising 9 clinical features with ~90% likelihood of identifying a subsequent PSP diagnosis. These features included known PSP symptoms, common misdiagnoses, and 2 novel associations, diabetes mellitus and cerebrovascular disease, which are possible modifiable risk factors for PSP. <b>Conclusion:</b> In this case-control study using data from electronic medical records, we identified 9 clinical features, including 2 previously unknown factors, associated with the pre-diagnostic stage of PSP. These may be used to facilitate recognition of PSP and reduce time to referral by primary care physicians.
Relation between DSIS and DSCQS for temporal and spatial video artifacts in a wireless home environment (2007)

To interpret the impressions of observers, it is necessary to understand the relationship between components that influence perceived video quality. This paper addresses the effect of assessment methodology on the subjective judgement for spatial and temporal impaired video material, caused by video adaptation methods that come into play when there is variable throughput of video material (I-Frame Delay and Signal-to-Noise Ratio scalability). Judgement strategies used are the double-stimulus continuous-quality scale (DSCQS) and the double stimulus impairment scale (DSIS). Results show no evidence for an influence of spatial artifacts on perceived video quality with the presented judgement strategies. Results for the influence of temporal artifacts are less easy to interpret, because it is not possible to distinguish whether the non-linear relation between DSIS and DSCQS appeared because of the temporal artifacts themselves or presented scene content.
Pre-transplant presence of antibodies to MICA and HLA class I or II are associated with an earlier onset of bronchiolitis obliterans syndrome in lung transplant recipients. (2012)

Previous reports using cell-based methods (CDC-AHG) suggest that the presence of pre-transplant HLA Class I and II antibodies are associated with worse survival following lung transplantation. Similarly, antibodies to major histocompatibility complex Class I chain-related gene A (MICA) have been associated with increased graft failure following kidney transplantation. Using highly sensitive solid phase assays, we sought to determine whether the pre-transplant presence of antibodies to MICA or HLA Class I or II predicted short or long-term lung allograft function. Pre-transplant sera screened for antibodies to MICA by Labscreen Single Antigen format and HLA by Luminex (n = 192) revealed antibody presence in 31 (16.1%) and 70 (36.4%) patients, respectively. HLA antibody presence correlated with increased bronchiolitis Obliterans syndrome (BOS)-1 development at 3 years [32.9% (23/70) vs. 18.9% (23/122), p = 0.03] while MICA antibodies correlated with BOS-2 development [32.3% (10/31) vs. 14.9% (24/161), p = 0.02]. The presence of HLA or MICA antibodies correlated with BOS-1 development [32.5% (26/81) vs.18.0% (20/111), p = 0.02] and BOS-2 [24.7% (20/81) vs. 12.6% (14/111), p = 0.02] at 3 years. We found no correlation between antibody presence and episodes of acute cellular rejection or overall survival. We conclude that the presence of pre-transplant HLA or MICA antibodies is associated with earlier BOS onset following lung transplantation.
INTRAVITREAL BEVACIZUMAB AS SUPPLEMENTAL TREATMENT OR MONOTHERAPY FOR SEVERE RETINOPATHY OF PREMATURITY (2011)

Intravitreal bevacizumab may serve as a supplemental therapeutic agent for severe laser-refractory retinopathy of prematurity or as monotherapy when media opacities preclude diode laser photocoagulation or the patient is too sick for lengthy laser treatment.
CO<sub>2</sub> Storage Capacity In Tertiary-Age Gulf Coast Coals (2009)

The Gulf Coast region contains a large, under-explored, Tertiary-age coal belt. These coals, deposited within the greater Wilcox Group cover an area stretching from southern Texas along the Gulf’s Margin, as far north as Arkansas and Tennessee, and as far east as the Florida panhandle. The Gulf Coast Tertiary Coals are deposited over an aerially extensive margin along the Northern Gulf Coast and achieve significant vertical thicknesses. Lower Wilcox coals may be present in as many as 5 to 10 seams, providing a net thickness of 15 to 25 feet when the individual seams are grouped together over a gross interval of hundreds of feet. These coals dip towards the Gulf of Mexico coastline and are found at depths of 1,000 feet to depths greater than 7,000 feet. The CO2 storage capacity of these coals is determined using adsorption isotherms from samples throughout the region. The Tertiary coal belt is divided into three sub-plays based on geologic and political boundaries. Each sub-play has unique coal properties used in the storage calculations. These properties include area, depth, thickness, and porosity and are used with the adsorption isotherms to estimate the overall CO2 storage capacity. The total CO2 storage capacity estimate of these coals ranges from 20 to 28 billion metric tons (380 to 540 trillion cubic feet).
Two cases of disseminated trichosporon beigelii infection treated with combination antifungal therapy (1990)

Two patients with acute leukemia in whom disseminated Trichosporon beigelii infection developed are reported. The T. beigelii infection developed in the first patient while he was receiving 5-fluorocytosine. He was treated with amphotericin B in addition to 5-fluorocytosine. Despite the continued antifungal therapy, multiple organs were invaded by the organisms at autopsy. The second patient was treated with miconazole and norfloxacin. Although this combination antifungal therapy seemed to be effective, this patient required splenectomy for cure of the infection.
Pseudomorphic In/sub 0.7/Ga/sub 0.3/As/In/sub 0.52/Al/sub 0.48/As HEMTs with super-flat interfaces fabricated on [411] A-oriented InP substrates (2002)

In this paper, we report the device fabrication and characteristics of 50-nm-gate pseudomorphic In/sub 0.7/Ga/sub 0.3/As/In/sub 0.52/Al/sub 0.48/As high electron mobility transistors (HEMTs) grown on a [411]A-oriented InP substrate by molecular beam epitaxy, which is the first report, to our knowledge, of HEMTs grown on any InP substrate except a conventional [100]-oriented InP substrate. The pseudomorphic HEMTs on the [411]A InP substrate showed a higher electron mobility than those on the [100] InP substrate at not only low temperatures but also room temperature. The [411]A HEMTs provided excellent DC and RF characteristics, showing a very high transconductance (1.1 S/mm) and one of the best cutoff frequencies (355 GHz) ever reported.
A method of utilizing lithium-induced nuclear reactions in the determination of carbon, nitrogen, and oxygen in thin films (1975)

A method of analysis of oxygen, nitrogen, and carbon in thin samples involves the detection of charged particles from nuclear reactions induced by a 7-MeV lithium-6 beam. The particle detection with a telescope counter near 0° takes full advantage of high exothermic reactions. The sensitivity is of the order of 10−3 μg/cm2. A preliminary study of the contaminants introduced during the sputtering of niobium is presented.
Experimental Investigation of Four Transmit Antenna Space-Time Block Codes (2006)

Space-time trellis and space-time block codes harness the effects of spatial diversity by taking advantage of multiple independently fading transmit and receive antenna paths between the transmitter and receiver. In this paper, we present experimental studies primarily on the performance of four transmit antenna space-time block codes which, although promising in simulations, need to be investigated in real-world wireless channels. Simulations often inaccurately model the wireless channel impulse response and other impairments such as interference, signalfading, multipath, phase noise, etc. Experimental results reveal an improvement in reliability by use of space-time block codes as predicted in simulations. However, the theoretical diversity gains promised in the simulations cannot be fully realized because of what is believed to be interference generated by other RF sources on the same 2.4GHz WLAN band on which the experiments were conducted.
Bright single InAs quantum dots at telecom wavelengths in site-selective InP nanowires (2017)

Non-classical light sources that can produce streams of correlated on-demand photons are a central building block for optics based quantum information technologies. There are numerous possible approaches for producing such a light source. One of the most promising is the solid-state single photon source based on a single quantum dot in III-V semiconductors. Utilizing a single InAs quantum dot in an InP nanowire, we previously demonstrated a bright and efficient source for single photons [1] and entangled photon pairs [2] that emits around 950 nm. In order to interface with telecom systems, single photon sources emitting at longer wavelengths are required. A few works have extended the emission to the telecom band using a single InAs/InP quantum dot in a micro-cavity [3-4]. However, improving the source brightness and the extraction efficiency remains a challenging task. In this contribution, by modifying the growth conditions and the pre-growth pattern for an InAs dot in an InP nanowire, we demonstrate a bright light source that emits in the telecom O-band, an important step towards the demonstration of a single photon source.
Bacterial Detection Using Unlabeled Phage Amplification and Mass Spectrometry through Structural and Nonstructural Phage Markers (2014)

According to the World Health Organization, food safety is an essential public health priority. In this context, we report a relevant proof of feasibility for the indirect specific detection of bacteria in food samples using unlabeled phage amplification coupled to ESI mass spectrometry analysis and illustrated with the model phage systems T4 and SPP1. High-resolving power mass spectrometry analysis (including bottom-up and top-down protein analysis) was used for the discovery of specific markers of phage infection. Structural components of the viral particle and nonstructural proteins encoded by the phage genome were identified. Then, targeted detection of these markers was performed on a triple quadrupole mass spectrometer operating in the selected reaction monitoring mode. E. coli at 1 × 10(5), 5 × 10(5), and 1 × 10(6) CFU/mL concentrations was successfully detected after only a 2 h infection time by monitoring phage T4 structural markers in Luria-Bertani broth, orange juice, and French bean stew ("cassoulet") matrices. Reproducible detection of nonstructural markers was also demonstrated, particularly when a high titer of input phages was required to achieve successful amplification. This strategy provides a highly time-effective and sensitive assay for bacterial detection.
Mechanism of Chromium(VI) Toxicity in Escherichia coli: Is Hydrogen Peroxide Essential in Cr(VI) Toxicity? (1995)

To investigate the role of hydrogen peroxide in Cr(VI) toxicity in vivo toward bacterial cells, we examined the effect of Cr(VI), hydrogen peroxide, sodium azide, and mannitol on the viability of Escherichia coli. Bacterial cells were incubated for 1 h with shaking in the presence of Cr(VI), hydrogen peroxide, sodium azide as catalase inhibitor, and/or mannitol as radical scavenger. The colony-forming ability and double-strand DNA degradation were examined. The viability assays revealed that Cr(VI) toxicity depended on hydroxyl radicals generated in the reaction involving hydrogen peroxide and chromium. Moreover, incubation of E. coli cells with 10 mM Cr(VI) and 3 mM hydrogen peroxide caused the degradation of double-strand DNA in vivo, which was suppressed by the addition of mannitol. These results indicated that hydroxyl radicals generated in the incubation degraded DNA of E. coli cells, resulting in cell death. In the absence of added hydrogen peroxide, the intracellular concentration of hydrogen peroxide in E. coli was low (below 1 microM). A catalase-defective strain incubated in the absence of added hydrogen peroxide remained fully viable after 1 h but showed decreased viability after prolonged incubation (4-8 h). The addition of mannitol suppressed this decrease, suggesting that hydroxyl radicals may be involved in the expression of Cr(VI) toxicity even without added hydrogen peroxide.
Antigenic stimulation with cytochrome P450 2J expressed in mouse hepatocellular carcinoma cells regulates host anti-tumour immunity (2009)

Cytochrome P450 2J subfamily (CYP2J) enzymes expressed in mouse hepatocellular carcinoma (HCC) cells were identified as an antigen recognized by specific CD4(+) T cells and the structure of its T cell epitope was determined by proteomics-based exploration. The major histocompatibility complex (MHC) class II binding peptides were isolated from I-A(k)/peptide complex of dendritic cells (DCs) loaded or unloaded with MIH-2 mouse HCC cells. MHC class II-binding peptides found in MIH-2-loaded DCs but not in unloaded DCs were determined by tandem mass spectrometric analysis. The peptide, consisting of amino acid 276-290 (DFIDAFLKEMTKYPE) of mouse CYP2J enzymes, was identified as an antigenic peptide presented in the context of MHC class II. Preventive treatment of mice with CYP2J peptide stimulated interferon (IFN)-gamma production of splenocytes and suppressed the growth of implanted CYP2J-positive MIH-2 cells but not CYP2J-negative murine bladder tumour cells. However, continuous treatment of MIH-2-bearing mice with CYP2J peptide significantly suppressed IFN-gamma production of splenocytes and accelerated the growth of implanted MIH-2 tumours in vivo. Increased frequencies of CD4(+)forkhead box P3 regulatory T cells and CD11b(+)Gr-1(+) myeloid suppressor cells were observed in splenocytes from the continuously immunized mice. These results indicate that antigenecity of CYP2J isoforms expressed in HCC cells activate host anti-tumour immunity at an initial stage of HCC, but suppress host anti-tumour immunity with excessive antigenic stimulation at an advanced stage.
Super-oscillatory Optical Needle for Heat Assisted Magnetic Recording (2013)

We demonstrate an alternative to plasmonic focusing, a super-oscillatory focusing lens capable of producing a 51nm spot for optical heating in heat assisted magnetic recording using a diode laser operating at 473 nm wavelength.
Development of a Sliding Plate Rheometer to Measure the High Frequency Viscoelastic Properties of Polymer Melts (2007)

Abstract A newly designed and constructed sliding plate rheometer is used to measure the high frequency (210 Hz) linear viscoelastic properties of two model polymers: polybutene (PB) and polydimethylsiloxane (PDMS). Using well-known rheological models, extrapolations of the viscoelastic measurements obtained on a rotational parallel plate rheometer to a frequency of 210 Hz are used to assess the performance of the high frequency sliding plate rheometer. Good agreement between the extrapolated and measured data demonstrates the ability of the sliding plate rheometer to measure the high frequency rheological properties of both Newtonian and shear-thinning materials.
Epidemiological evidence for metabolic programming in dairy cattle (2016)

In humans, there is evidence that metabolic diseases occurring in later life arise in utero as a result of programming of key endocrine systems during suboptimal intrauterine conditions. The process by which prenatal insults lead to permanent changes in tissue structure and function, and finally to low birthweight (BW), is known as developmental programming. Poor nutrition, environmental temperature, oxygen availability and overnutrition all have been shown to significantly affect intrauterine development. Because the placenta is the organ for communication between mother and fetus, placental insufficiency invariably affects embryonic development and health in later life. In order to optimise their income, dairy farmers inseminate their nulliparous heifers at adolescent age, and subsequently strive for calving intervals not longer than 380 days. Hence, heifers are still growing and multiparous animals are still yielding large quantities of milk while pregnant. Dairy cows heavily selected for milk yield have specific endocrinological characteristics, like low peripheral insulin levels and low peripheral insulin sensitivity, both contributing to safeguard glucose for milk production. The reverse of this advanced selection is the high incidence of a wide range of metabolic diseases. Evidence from epidemiological studies is now available demonstrating that milk yield during gestation and environmental factors, such as season of pregnancy and parturition, affect both the size and the intermediary metabolism of the neonatal calf. The latter suggests that further optimisation in terms of production, reproduction, general health and longevity in the dairy sector may be feasible by taking into account environmental factors occurring during pregnancy.
A New Approach for Simultaneous DEMS and EQCM: Electro‐oxidation of Adsorbed CO on Pt and Pt‐Ru (1999)

The combination of differential electrochemical mass spectrometry (DEMS) and electrochemical quartz crystal microbalance (EQCM) is possible by means of a new dual thin layer cell. Thus, simultaneous real‐time measurements of volatile products and deposited (or dissolved) species can be performed, which is demonstrated for CO‐adsorption and desorption processes on Pt and a Pt‐Ru alloy in sulfuric acid. In particular, it is shown that on a Pt‐Ru alloy, electrode anions are adsorbed even at 0 mV vs. reversible hydrogen electrode. © 1999 The Electrochemical Society. All rights reserved.
GROWTH AND TOTAL CONTENT OF PHYLLANTIN AND HYPOPHYLLANTIN IN GREEN MENIRAN (Phyllanthus niruri L.) AND RED MENIRAN (Phyllanthus urinaria L.) IN VARIOUS WAYS OF FERTILIZATION (2016)

The objective of this research was to identify the effects of various ways of fertilizer on growth and phyllantin contents and also hypophyllantin of two species Phyllanthus (Phyllanthus niruri L. and Phyllantus urinaria L.) The research was conducted at Lahan Penelitian IPB Babakan Sawah Baru, Bogor, West Java with an altitude of 250 m above sea level from February to May 2010. Experiment based on randomized block design (RBD)\nfactorial which divided in two factors. The first factor was about the fertilization (P) that consisted of soil (P0 = without fertilizer), manure (P1), fertilizer NPK (P2), manure + NPK fertilizer (P3). The second factor was two species of meniran (Phyllanthus) which consists of M1 = green meniran (Phyllanthus niruri L.) from Bangkalan\n(A6), M2 = green meniran (Phyllanthus niruri L.) from Gresik (A7), and M3 = red meniran (Phyllanthus urinaria\nL.) from Bangkalan (A13). The results said that to increase growth and achieve high biomass production; green meniran (Phyllantus niruri L.) accession (A6 and A7) need a combination of fertilizer manure + NPK. Green\nmeniran (A7) found to contain the highest amounts of phyllanthin (0.17% dry weight) and hypophyllantin (0.26%\ndry weight) with given of manure.