gebhart/patrepeval huggingface dataset:
Lipid-induced ordered conformation of some peptide hormones and bioactive oligopeptides: predominance of the helix over the .beta.-form (1982)

The conformation of several naturally occurring peptide hormones and bioactive oligopeptides in phospholipid solutions was studied by circular dichroism. Phosphatidylcholine induced a partial helix in human gastrin I at neutral pH, but phosphatidylserine did not unless the five consecutive glutamic acid residues in gastrin were protonated. Reduced somatostatin with two lysines and substance P with one arginine and one lysine were partially helical in phosphatidylserine, but not phosphatidylcholine, solution. Both lipids induced a helical conformation in glucagon and its COOH-terminal fragment (19-29) probably because the helical segment is primarily located at the uncharged COOH terminus. Thus, polypeptides with a helix-forming potential can have the helical conformation only when the peptides carry no charge or charges opposite to those on the polar head of the lipid. Renin substrate, which has potentials for the beta form and beta turn, seemed to form a mixture of the two conformations in phosphatidylserine solution. Angiotensin I with a strong probability for the beta form adopted the beta form in phosphatidylserine solution and sleep peptide with no structure-forming potential remained unordered in lipid solutions. The helix usually predominated over the beta form in lipid solutions if the peptide has potentials for both conformations. This could account for the preponderance of helices in bacteriorhodopsin of the purple membrane, which according to its amino acid sequence would have favored the beta form.
Purification to apparent homogeneity and partial characterization of rat liver UDP-glucose:glycoprotein glucosyltransferase. (1992)

The UDP-Glc:glycoprotein glucosyltransferase is a soluble protein of the endoplasmic reticulum that catalyzes the glucosylation of protein-linked, glucose-free, high mannose-type oligosaccharides. In vivo, the newly glucosylated compounds are immediately deglucosylated, presumably by glucosidase II. The glucosyltransferase has been purified to apparent homogeneity from rat liver. The enzyme appears to have a molecular weight of 150,000 and 270,000 under denaturing and native conditions, respectively. The pure enzyme shows an almost absolute requirement for Ca2+ ions and for UDP-Glc as sugar donor. The same as crude preparations, the pure enzyme synthesized Glc1 Man7-9GlcNAc2-protein from Man7-9GlcNAc2-protein. Denatured glycoproteins are glucosylated much more efficiently than native ones by the apparently homogeneous glucosyltransferase. Availability of the pure enzyme will allow testing the possible involvement of transient glucosylation of glycoproteins in the folding of glycoproteins and/or in the mechanism by which cells dispose of malfolded glycoproteins in the endoplasmic reticulum.
Measuring Domestic Violence in an Alcoholic Population (1986)

A survey of 107 adults receiving residential treatment for substance abuse was conducted, to determine characteristics of domestic violence in relationships. The survey incorporated instruments to measure the degree of substance abuse (the Michigan Alcoholism Screening Test or MAST) as well as types and frequencies of domestic violence (the Conflict Tactics Scale or CTS-N). Findings are then compared to a national study of 2143 normals (Straus, Gelles, & Steinmetz, 1980) to ascertain differences in domestic violence. Findings indicate that 83% of alcoholic subjects behaved violently in past relationships, compared to 28% of the normal population. Fifty-five percent of the alcoholics had been violent in a relationship during the past year, compared to 16% of the normals who were violent during that time. The findings also indicate that violence in alcoholic relationships is far more frequent and severe than in nonalcoholic relationships. The implications of these findings for clinical practice are discussed.
Block copolymers based on poly(vinylidene fluoride) (2015)

In de afgelopen decennia zijn de hardware afmetingen van elektronische apparatuur voor draagbare smartphones, laptops en camera’s steeds verder afgenomen, terwijl hun prestaties enorm zijn toegenomen. Om deze trend in de toekomst voort te zetten is er een noodzaak om alternatieve materialen te ontwikkelen. In dit onderzoek wordt gebruik gemaakt van het bijzondere karakter van blokcopolymeren om nieuwe materialen te ontwikkelen voor dataopslagapparatuur die is ingebouwd in de elektronische apparatuur die wij dagelijks gebruiken. Blokcopolymeren zijn grote moleculen opgebouwd uit twee verschillende polymeerblokken. Aangezien beide blokken niet mengbaar zijn (net zoals water en olie), zullen ze fasescheiden op de nanoschaal in domeinen met een hoge mate van ordening. De nauwkeurige zelforganisatie van blokcopolymeren – toegepast in dit onderzoek – is een handige manier om elektronische apparaten op te bouwen, omdat de moleculen spontaan geordende structuren vormen en de afmetingen en functionaliteit gemakkelijk kunnen worden aangepast. In dit onderzoek hebben we blokcopolymeren gemaakt waarin één van de blokken ferro-elektrisch is. Ferro-elektrische materialen kunnen zich bevinden in verschillende gepolariseerde toestanden ("1" en "0") en de polarisatie kan worden omgeschakeld met een elektrisch veld, waardoor het mogelijk is om data op te slaan. We hebben onze blokcopolymeren gebruikt om geordende ferro-elektrische nanoschuimen te produceren. Daarna hebben we het polymeerschuim opgevuld met magnetische verbindingen, wat leidde tot een multiferroïsch materiaal samengesteld uit ferro-elektrische en ferromagnetische domeinen. Mogelijke koppeling tussen de elektrische en magnetische eigenschappen geeft de mogelijkheid om data elektrisch te schrijven en magnetisch uit te lezen.
Reducing Tire Rolling Resistance to Save Fuel and Lower Emissions (2008)

<div class="htmlview paragraph">In a context of a renewable and sustainable progress in the automotive industry where fuel and respect for the environment are in the middle of all concerns, energy efficient tires could play a significant role in saving money, limiting greenhouse gases and contributing to reduced local pollution. Using simulation, this paper establishes a simple law to predict fuel savings between two tire configurations, which appear to be almost independent of the usage and which depend on the difference of rolling resistance coefficients, the actual weight of the vehicle and the fuel type. This approach has been evaluated in practice for passenger car tires fitted on one gasoline and one Diesel Midsize car by performing rolling resistance tests, coast down tests, fuel consumption tests at constant speed and emissions recorded on a test bench. Even more than just validating the fuel savings prediction law, the test results also show how low rolling resistance tires can help to decrease CO<sub>2</sub> emissions and local pollutants such as CO emissions for gasoline engines and NO<sub>x</sub> emissions for Diesel engines. This conclusion of simultaneous CO<sub>2</sub> and NO<sub>x</sub> reduction has also been proven at constant speed on a heavy duty vehicle equipped with a gas analyzer.</div>
Use of praziquantel in patients with schistosomiasis mansoni previously treated with oxamniquine and/or hycanthone: resistance of Schistosoma mansoni to schistosomicidal agents (1982)

Fourteen patients with active schistosomiasis mansoni in spite of previous treatment with oxamniquine and/or hycanthone were treated with praziquantel, single oral dose of 45 to 50 mg/kg body-weight. All underwent clinical, laboratory and electrocardiographic examination before and after treatment. Untoward effects (dizziness, drowziness, nausea and abdominal pain) were observed in ten. Laboratory findings disclosed no significant alteration and the electrocardiograms showed no abnormalities. Monthly follow-up examinations of 13 patients for six consecutive months showed parasitological cure in all. Before praziquantel treatment strains of Schistosoma mansoni were isolated from two patients, one treated three times with oxamniquine and the other with hycanthone once and oxamniquine twice. Progenies of these strains were maintained in Biomphalaria glabrata and mice. Groups of these infected mice were then treated with oxamniquine, hycanthone, niridazole and praziquantel and results compared with the BH strain maintained in our laboratory for many years. Schistosomicidal activity was assessed by the localization of worms in the portal vein system and oogram changes. Progenies from the strains isolated in this study were resistant to oxamniquine and hycanthone but sensitive to niridazole and praziquantel. The BH strain was sensitive to all four drugs. The serial runs of S. mansoni strains through intermediate and definitive hosts have not influenced their reactions to these schistosomicides.
Multitumor “Sausage” Blocks in Immunohistochemistry Simplified Method of Preparation, Practical Uses, and Roles in Quality Assurance (1991)

This report describes a simplified method for preparing multitumor sausage blocks (MTSBs) for use in immunohistochemical procedures. Rather than relying on previously processed paraffin blocks as a source of material, this procedure involves procuring tissue at the time of gross specimen examination. The tissue is processed along with routine surgical pathologic material, and the paraffinized samples are placed in "storage cassettes" for easy cataloging and storage. Thin strips are cut from the tissue in the "storage cassettes" and combined by dripping liquid paraffin onto them while they are rolled between the thumbs and forefingers, somewhat like making a cigarette. This results in a tissue "log." Transverse sections of the "log" are embedded in paraffin blocks and used as MTSBs. Practical uses of MTSBs are discussed, and their role in quality assurance is stressed.
HARP AND PIANO (1965)

Journal Article HARP AND PIANO Get access Ami, Ma'ayani, Concerto. Arrangement for harp and piano. ( Israel Music Institute, Tel Aviv, 1964, £1 10s.) O. E. O. E. Search for other works by this author on: Oxford Academic Google Scholar Music and Letters, Volume XLVI, Issue 4, October 1965, Pages 372-b–373, https://doi.org/10.1093/ml/XLVI.4.372-b Published: 01 October 1965
High speed test adapters in the functional test environment (2002)

Problems encountered in the design and operation of high-speed test adapters are discussed. The information presented addresses the problems associated with high-speed functional test fixtures, and the methods found for resolving them. Particular attention is given to adapter design requirements, electrical and mechanical considerations, and circuit board advantages.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Forecasting Charging Demand of Electric Vehicles Using Time-Series Models (2021)

This study compared the methods used to forecast increases in power consumption caused by the rising popularity of electric vehicles (EVs). An excellent model for each region was proposed using multiple scaled geographical datasets over two years. EV charging volumes are influenced by various factors, including the condition of a vehicle, the battery’s state-of-charge (SOC), and the distance to the destination. However, power suppliers cannot easily access this information due to privacy issues. Despite a lack of individual information, this study compared various modeling techniques, including trigonometric exponential smoothing state space (i.e., Trigonometric, Box–Cox, Auto-Regressive-Moving-Average (ARMA), Trend, and Seasonality (TBATS)), autoregressive integrated moving average (ARIMA), artificial neural networks (ANN), and long short-term memory (LSTM) modeling, based on past values and exogenous variables. The effect of exogenous variables was evaluated in macro- and micro-scale geographical areas, and the importance of historic data was verified. The basic statistics regarding the number of charging stations and the volume of charging in each region are expected to aid the formulation of a method that can be used by power suppliers.
Photo‐induced protein cross‐linking to 5S RNA and 28–5.8S RNA within rat‐liver 60S ribosomal subunits (1985)

Rat liver 60S ribosomal subunits were irradiated with 254-nm ultraviolet light (1.26 X 10(4) quanta/subunit), under conditions which preserved their functional activity. Cross-linked RNA-protein complexes were recovered after unreacted proteins had been removed by repeated acetic acid extractions. Proteins linked to the whole rRNA, to 5S RNA and to 28-5.8 S RNAs were identified by two-dimensional gel electrophoresis after RNA hydrolysis by ribonucleases T1 and A. Our results showed that numerous proteins interact with rRNAs (at least ten with 28-5.8 S RNA, eight with 5S RNA and among these three are common to both) and have been discussed in the light of all the available data.
[The impact of ecological pressing on tuberculosis and nonspecific lung diseases in the Astrakhan' region]. (1997)

The correlation analysis was used to examine the epidemiological indices of the morbidity of tuberculosis, pneumonia, chronic bronchitis, bronchial asthma, and lung cancer in the Astrakhan region in 1987-1994. The indices were compared with each other and with varying air, water, and soil levels of toxicants. The magnitude of the effects of pollutants on the incidence of respiratory diseases ranged from 61% (for tuberculosis) to 93.3% (for pneumonia). The effects of the water and soil concentrations of toxicants proved to be less insignificant, by varying from 28.7% in tuberculosis to 4.8% in lung cancer. The effects of toxicant levels on tuberculosis morbidity are 5 times less than those during fibrous-cavernous processes and twice less than in first detected tuberculosis at the stage of decay with bacterial isolation. The pollutants containing sulfur were found to adversely affect mainly patients with tuberculosis or lung cancer. The study makes it necessary to consider patients with the aforesaid diseases as the objects of ecological pressing that directly has impact on the course of diseases and their outcomes.
A comparison of keystroke dynamics techniques for user authentication (2015)

Recently, in the Internet, one of the most security vulnerabilities is a weak password setting. There are several ways to make the password harder to guess by increasing the number of characters, password complexity, or changing the password more often. However, using only passwords for authentication may not be enough because passwords can be written down or exposed to others easily. Therefore, several researchers are solving this problem by adding keystroke dynamics to a username or a password to strengthen the authentication process. In this work, three keystroke dynamics techniques, i.e. statistics using confidence interval, k-means clustering, and trajectory dissimilarity, are implemented and compared with the same dataset. The performance metric is accuracy. In addition, pseudocodes for the techniques are also presented. From the experiment, the trajectory dissimilarity technique gives the best accuracy at 96% among others.
Cloning and molecular characterization of the Δ6‐desaturase from two <i>Echium</i> plant species: Production of GLA by heterologous expression in yeast and tobacco (2002)

The synthesis of GLA (delta6,9,12-1-8:3) is carried out in a number of plant taxa by introducing a double bond at the delta6 position of its precursor, linoleic acid (delta9,12-18:2), through a reaction catalyzed by a delta6-desaturase enzyme. We have cloned genes encoding the delta6-desaturase (D6DES) from two different Macaronesian Echium species, E. pitardii and E. gentianoides (Boraginaceae), which are characterized by the accumulation of high amounts of GLA in their seeds. The Echium D6DES genes encode proteins of 438 amino acids bearing the prototypical cytochrome b(5) domain at the N-terminus. Cladistic analysis of desaturases from higher plants groups the Echium D6DES proteins together with other delta6-desaturases in a different cluster from that of the highly related delta8-desaturases. Expression analysis carried out in E. pitardii shows a positive correlation between the D6DES transcript level and GLA accumulation in different tissues of the plant. Although a ubiquitous expression in all organs is observed, the transcript is particularly abundant in developing fruits, whereas a much lower level is present in mature leaves. Functional characterization of the D6DES gene from E. gentianoides has been achieved by heterologous expression in tobacco plants and in the yeast Saccharomyces cerevisiae. In both cases, overexpression of the gene led to the synthesis of GLA. Biotechnological application of these results can be envisaged as an initial step toward the generation of transgenic oleaginous plants producing GLA.
Applications for Radio‐frequency Identification Technology in the Perioperative Setting (2014)

We implemented a two-year project to develop a security-gated management system for the perioperative setting using radio-frequency identification (RFID) technology to enhance the management efficiency of the OR. We installed RFID readers beside the entrances to the OR and changing areas to receive and process signals from the RFID tags that we sewed into surgical scrub attire and shoes. The system also required integrating automatic access control panels, computerized lockers, light-emitting diode (LED) information screens, wireless networks, and an information system. By doing this, we are able to control the flow of personnel and materials more effectively, reduce OR costs, optimize the registration and attire-changing process for personnel, and improve management efficiency. We also anticipate this system will improve patient safety by reducing the risk of surgical site infection. Application of security-gated management systems is an important and effective way to help ensure a clean, convenient, and safe management process to manage costs in the perioperative area and promote patient safety.
A needle type therapeutic system incorporating laser light and lumin for immunotherapy of cancer growing in deep organs (1996)

Lumin is a potent cell-activating agent and a photosensitizer characterized by absorption peaks at 670 nm and 770 nm. It has already been demonstrated that macrophase activity is enhanced greatly by lumin administration with laser light irradiation and that this method is useful in cancer immunotherapy. In this study, a new needle type therapeutic system was developed for the immunotherapy of cancer growing in deep human organs. A human lung cancer grafted onto nude mice was strongly cicatrized by collagen fibres about four weeks after the first treatment. The collagen fibres seemed to seal-off the tumor and prevent its growth with intense cicatrization. In addition, a high T/B cell ratio of lymphocytes was observed in the peripheral blood of the treated mice, although the thymus is congenitally absent from nude mice. These results demonstrated that the system is a reliable method for cancer treatment in deep organs without side effects and/or major surgical intervention.
All optical, high contrast absorptive modulation in an asymmetric Fabry–Perot étalon (1991)

We report a 27:1 switching contrast ratio with 2.5 mW of power in an asymmetric Fabry–Perot étalon. The modulation is achieved by optical saturation of the excitonic absorption profile of a 95 Å GaAs/AlGaAs multiple quantum well structure grown on a high-reflectivity dielectric stack mirror.
Structured Dirty Paper Coding with Known Interference Structure at Receiver (2006)

The Tomlinson-Harashima precoding is well known for dirty paper coding implementation. Despite its simplicity, THP suffers from a significant performance loss in the low SNR region due to modulo operations. In this paper, we propose new dirty paper precoding scheme by taking advantage of the known modulation structure of interference (e.g., BPSK and QPSK signals). The new method, termed structured DPC (SDPC), outperforms the regular THP with modest changes to the transmitter and receiver. For BPSK and QPSK cases investigated, the SDPC only suffers power loss, which is up to 1.25 dB compared with non-interference case, while the regular THP-based scalar dirty paper coding has a typical 4-5 dB capacity loss in the same low SNR regions
Orientalist Sociology and the Creation of Colonial Sexualities (2000)

In what Arjun Appadurai has dubbed the ‘colonial imaginary’ issues of femininity, and who possessed it, were of prime importance. An orientalizing sociology sought to distinguish, and indeed to fix, differences between metropolitan and indigenous women as a rhetoric of hierarchy which secured proper and western femininity to white women. One critical route which colonial commentators and authorities took to produce that knowledge was to measure women's proximity to the practice of prostitution, a means which permitted discussion and judgement of racialized sexualities as well as of proper models of feminine behaviour. This article will explore the ways in which the new sociology of the Victorian period, wielded in a colonial context, served to separate women through race-based ideas of sexual behaviour and sexual order. It will deal with British India in the nineteenth and early twentieth centuries.
Osmotic Reversal of Temperature Sensitivity in <i>Escherichia coli</i> (1973)

Forty temperature-sensitive mutants, unable to grow on tryptone or nutrient agar at 42 C, were isolated from Escherichia coli K-12. When 0.5% NaCl was added to the medium, 32 grew at the nonpermissive temperature. Several were tested with different amounts of NaCl added to tryptone broth; all grew best when the osmolality of the medium was between 400 and 1,000 milliosmolal. One of the mutants was studied in more detail. Sucrose, inositol, KCl, and MgCl(2), as well as NaCl, permitted growth at 42 C. Glycerol, however, had no effect. When shifted from 30 to 42 C without osmotic protection, the mutant stopped growing but did not lyse, die, or leak significant amounts of intracellular material. In a similar shift experiment, a second mutant leaked all of its trichloroacetic acid-soluble pools into the medium. The majority of the mutants were hypersensitive to certain antibiotics, indicating possible cell envelope defects.
Mean cell volumes of neutrophils and monocytes are promising markers of sepsis in elderly patients (2013)

MNV and MMV, which can be obtained easily using an automated blood analyzer, may be promising hematologic parameters for distinguishing elderly individuals with and without sepsis and may help clinicians in the diagnosis of sepsis.