gebhart/patrepeval huggingface dataset:
[Arterial hypertension. Prevention in infants with congenital urinary tract malformations]. (1992)

Eighty-nine newborns and infants with congenital urinary tract malformations were treated in the childrens' hospital of the Westfälische Wilhelms-University from 1986 to 1989. Twenty patients of this group (22.5%) developed severe hypertension requiring treatment within the first year of life. Mean age of diagnosis of hypertension was 5 months (range 0.5-12 months). Median values for blood pressure at time of diagnosis were 138 mmHg (range 120-170) for systolic and 92 mmHg (range 80-110) for diastolic values. Six patients showed characteristic symptoms for hypertension such as restlessness, sweating and sleep disorders. Plasma levels of renin were obtained in 12 of 20 patients. Five patients had raised plasma renin levels. All patients with a severe hypertension were treated with one to several antihypertensive drugs. Risk factors for the development of severe renal hypertension in early infancy are cystic renal malformation, vesico-ureteral reflux, obstructive uropathy and to our experience also short term percutaneous nephrostomy in obstructive uropathy in particular in connection with pyelonephritis. Hypertension can still appear after the successful surgical correction of urinary obstruction. We describe the group of patients with severe hypertension in our study group; diagnostic principles and our therapeutic approach are explained. We conclude that early diagnosis of severe hypertension and consecutive treatment are important in infants with congenital urinary malformations.
Joint Adaptive Redundancy and Partial Retransmission for Reliable Transmission in Wireless Sensor Networks (2008)

As a potentially competitive technique, erasure coding has been employed in wireless sensor networks (WSNs) to enhance transmission reliability. In this paper, to design a practical and efficient redundancy mechanism in WSNs, we firstly provide a theoretical study of packet delivery probability and average energy consumption for retransmission and redundancy mechanisms. The theoretical results indicate that in WSNs, the adaptive redundancy coding mechanism is more energy efficient than retransmission while keeping the same level of reliability in most scenarios. Then based on the mapping table and two basic design principles obtained from the theoretical analysis, we propose a reliable transport protocol ARRTP which combines the adaptive redundancy mechanism and partial retransmission. The simulation and trace-driven results both verify that when the loss probability varies from low to high, our protocol provides reliability with comparably lower energy consumption. Furthermore, compared with fixed redundancy degrees, the robustness of the adaptive mechanism are also evaluated.
Losses and Physiologic Requirements for Water and Electrolytes after Extensive Burns in Children (1961)

BURNS are among the most common accidental injuries of infants and children and, when extensive, have mortality rates in excess of 50 per cent. When the burned area involves more than 20 or 30 per cent of the body surface the acute trauma is usually associated with a period of hypotension and generalized circulatory disturbance characterized as a shocklike state. Subsequently, alteration of circulatory hemodynamics in such vital organs as the brain and kidneys, tendency for accumulation of fluids in the burned areas, seepage from the traumatized surface and secondary adjustments of the extracellular and intracellular fluids to both injury . . .
A Web-based Distance Learning System for Robotics (2004)

로봇 관련 강의에서 여러 가지 개념을 용이하게 이해하기 위한 다양한 자료가 아직 부족하고, 한정된 기자재로 인하여 로봇을 이용한 실험을 충분히 수행하지 못하고 있는 실정이다. 이를 해소하기 위하여 본 논문에서는 멀티미디어 콘텐츠와 3차원 로봇 시뮬레이터로 구성된 웹기반 로봇 원격 교육시스템을 개발하고자 한다. 학생은 웹상에 구성된 멀티미디어 콘텐츠를 이용하여 로봇과 관련된 개념을 용이하게 이해할 수 있으며, 3차원 로봇 시뮬레이터를 이용하여 가상 로봇 실험 및 실제 로봇과의 연동 실험을 수행할 수 있을 것이다. In robotics classes, various types of materials about robotics are still needed for helping students to understand concepts easily, and it is difficult for all students to perform actual experiments because of the lack of the real robots. In order to solve these problems, this paper develops a web-based distance learning system for robotics, which consists of multimedia content sand a 3-dimensional robot simulator. Students can easily get multimedia contents and understand concepts about robots. Also, they can use a 3-dimensional robot simulator to Perform virtual robot experiments and connection experiments with real robots.
Macellibacteroides fermentans gen. nov., sp. nov., a member of the family Porphyromonadaceae isolated from an upflow anaerobic filter treating abattoir wastewaters (2011)

A novel obligately anaerobic, non-spore-forming, rod-shaped mesophilic bacterium, which stained Gram-positive but showed the typical cell wall structure of Gram-negative bacteria, was isolated from an upflow anaerobic filter treating abattoir wastewaters in Tunisia. The strain, designated LIND7H(T), grew at 20-45 °C (optimum 35-40 °C) and at pH 5.0-8.5 (optimum pH 6.5-7.5). It did not require NaCl for growth, but was able to grow in the presence of up to 2 % NaCl. Sulfate, thiosulfate, elemental sulfur, sulfite, nitrate and nitrite were not used as terminal electron acceptors. Strain LIND7H(T) used cellobiose, glucose, lactose, mannose, maltose, peptone, rhamnose, raffinose, sucrose and xylose as electron donors. The main fermentation products from glucose metabolism were lactate, acetate, butyrate and isobutyrate. The predominant cellular fatty acids were anteiso-C(15 : 0), C(15 : 0), C(17 : 0) 2-OH and a summed feature consisting of C(18 : 2)ω6,9c and/or anteiso-C(18 : 0), and the major menaquinones were MK-9, MK-9(H(2)) and MK-10. The G+C content of the genomic DNA was 41.4 mol%. Although the closest phylogenetic relatives of strain LIND7H(T) were Parabacteroides merdae, Parabacteroides goldsteinii and Parabacteroides gordonii, analysis of the hsp60 gene sequence showed that strain LIND7H(T) was not a member of the genus Parabacteroides. On the basis of phylogenetic inference and phenotypic properties, strain LIND7H(T) ( = CCUG 60892(T) = DSM 23697(T) = JCM 16313(T)) is proposed as the type strain of a novel species in a new genus within the family Porphyromonadaceae, Macellibacteroides fermentans gen. nov., sp. nov.
Mice lacking the VIP gene show airway hyperresponsiveness and airway inflammation, partially reversible by VIP (2006)

The mechanisms leading to asthma, and those guarding against it, are yet to be fully defined. The neuropeptide VIP is a cotransmitter, together with nitric oxide (NO), of airway relaxation, and a modulator of immune and inflammatory responses. NO-storing molecules in the lung were recently shown to modulate airway reactivity and were proposed to have a protective role against the disease. We report here that mice with targeted deletion of the VIP gene spontaneously exhibit airway hyperresponsiveness to the cholinergic agonist methacholine as well as peribronchiolar and perivascular cellular infiltrates and increased levels of inflammatory cytokines in bronchoalveolar lavage fluid. Immunologic sensitization and challenge with ovalbumin generally enhanced the airway hyperresponsiveness and airway inflammation in all mice. Intraperitoneal administration of VIP over a 2-wk period in knockout mice virtually eliminated the airway hyperresponsiveness and reduced the airway inflammation in previously sensitized and challenged mice. The findings suggest that 1) VIP may be an important component of endogenous anti-asthma mechanisms, 2) deficiency of the VIP gene may predispose to asthma pathogenesis, and 3) treatment with VIP or a suitable agonist may offer potentially effective replacement therapy for this disease.
Relation of echocardiographic left ventricular mass and hypertrophy to persistent electrocardiographic left ventricular hypertropy in hypertensive patients: the LIFE study (2001)

Persistent ECG LVH between screening and LIFE study baseline identified patients with greater LV mass and a higher prevalence of echocardiographic LVH, suggesting that these patients may be at higher risk for subsequent morbid and mortal events.
Chronic cough caused by angiotensin converting enzyme inhibitors. (1990)

Physicians should suspect ACE inhibitors as the cause of cough in patients whose symptom begins soon after the institution of therapy with this class of drugs. This is particularly important in patients without a personal or family history of atopy, with normal physical findings, chest radiographs, and lung function tests. Rather than subjecting the patient to an extensive workup, substitution of a different antihypertensive agent is an inexpensive way to show whether the ACE inhibitor is the cause of the chronic cough.
Lung volume, pressure, flow, and density relationships during constant-flow ventilation in dogs (1993)

Lung volume changes during constant-flow ventilation (CFV) using cannulas in the main stem bronchi were examined in six beagle dogs. The increase in lung volume was found to depend mainly on the outflow resistance to gas flow in the trachea and tracheal tube. The resistance changed with gas flow, indicating that gas flow was transitional between laminar and turbulent flow (resistance varies; is directly proportional to flow1.5). There was a small pressure gradient between trachea and alveoli (1.1-1.3 cmH2O) that was independent of flow rate or gas velocity out of the CFV cannulas. This was attributed to momentum transfer from the gas jet from the CFV cannulas modified by friction between the gas jet and the airway wall.
VACCINATION OF GENETICALLY SUSCEPTIBLE MICE AGAINST CHRONIC INFECTION WITH <i>NEMATOSPIROIDES DUBIUS</i> USING PERTUSSIGEN AS ADJUVANT (1983)

The intestinal nematode Nematospiroides dubius persists for prolonged periods in mice after a single oral administration of infective larvae. After multiple administrations of larvae, some inbred mouse strains (termed 'resistant') develop the capacity to expel the majority of adult worms from the intestines. Other mouse strains such as CBA/H and C57BL/6 (and, in particular, males) are far more susceptible in that they expel few, if any, adult worms after repeated doses of larvae and may die with high worm burdens. One means to accelerate rejection of adult worms in a primary infection is to presensitize mice with a small number of living adult worms injected intraperitoneally. However, an impressive vaccination effect of ectopically implanted worms has only been demonstrated to date in resistant mouse strains. In this paper, success has been achieved in vaccinating genetically susceptible mice against chronic primary infection with N. dubius. Young male specific pathogen-free (SPF)-derived C57BL/6 mice demonstrate greater than 90% resistance after injection of adult worms but only when further injected with pertussigen from Bordetella pertussis as adjuvant. Accelerated rejection of adult worms appears to be the principal manifestation of resistance in vaccinated mice. A high degree of protection has also been obtained in recipients of pertussigen plus the supernatant of a crude worm extract equivalent to less than 10 adult worms per mouse. Although no information is available on the effector mechanisms responsible for worm rejection in vaccinated mice, pertussigen is known to increase both immediate and delayed type hypersensitivity responses and to increase tissue sensitivity to histamine. A strategy which sensitizes recipients such that a subsequent challenge infection is not sustained, and which is effective in highly susceptible hosts, opens the way to vaccination against chronic intestinal infections in those hosts most in need of protection.
Protein Modifications in the D 2 Protein of Photosystem II Affect Properties of the Q<sub>B</sub>/Herbicide-Binding Environment (1993)

The D2 protein contains an extended loop (the D-de loop) between helices D and de at the reducing side of photosystem II (PS II). Characterization of D2 mutants of the cyanobacterium Synechocystis sp. PCC 6803 has indicated that the length and amino acid composition of the D-de loop are not critical for basic PS II functions, although most of the residues in that region are conserved phylogenetically. Here we show using herbicide binding and electron-flow inhibition measurements that drastic modifications in the D-de loop of the D2 protein modify the interaction of some PS II-directed herbicides with their binding niche. The stability of (semi)-reduced QB in its binding pocket is altered in at least two of the mutants, as indicated by a shifted peak temperature of the thermoluminescence signal originating from charge recombination involving QB. These results suggest a close functional association between the D-de loop of the D2 protein and the QB/herbicide-binding environment, which is viewed as being coordinated mostly by residues of the D1 protein. This represents one of the first examples of modification of the QB/herbicide-binding domain by mutations in the D2 protein.
Prospective Calculation of Identification Power for Individual Genes in Analyses Controlling the False Discovery Rate (2012)

Recent work on prospective power and sample size calculations for analyses of high-dimension gene expression data that control the false discovery rate (FDR) focuses on the average power over all the truly nonnull hypotheses, or equivalently, the expected proportion of nonnull hypotheses rejected. Using another characterization of power, we adapt Efron's ([2007] Ann Stat 35:1351-1377) empirical Bayes approach to post hoc power calculation to develop a method for prospective calculation of the "identification power" for individual genes. This is the probability that a gene with a given true degree of association with clinical outcome or state will be included in a set within which the FDR is controlled at a specified level. An example calculation using proportional hazards regression highlights the effects of large numbers of genes with little or no association on the identification power for individual genes with substantial association.
Chloroplast biogenesis 76. Regulation of 4-vinyl reduction during conversion of divinyl Mg-protoporphyrin IX to monovinyl protochlorophyllide a is controlled by plastid membrane and stromal factors (1997)

Most of the chlorophyll (Chl) a of green plants is formed via two biosynthetic routes, namely the carboxylic divinyl and monovinyl chlorophyll biosynthetic routes. These two routes are linked by (4-vinyl) reductases that convert divinyl tetrapyrroles to monovinyl tetrapyrroles by reduction of the vinyl group at position four of the macrocycle to ethyl. The activities of these two routes are very sensitive to cell disruption. For example in barley leaves, cell disruption, a mandatory step during plastid isolation, results in partial inactivation of the carboxylic divinyl route. Investigations with subplastidic fractions revealed that the carboxylic divinyl and monovinyl biosynthetic routes were regulated by a delicate interaction that involved plastid membranes, stroma, and reduced pyridine nucleotides. While the monovinyl biosynthetic route was very active in isolated plastid membranes, activation of the divinyl biosynthetic route required the joint presence of plastid membranes and stroma. Contrary to expectation, activity of the carboxylic divinyl biosynthetic route was greatly enhanced by addition of NADPH to the lysing buffer used during plastid membranes and stroma preparation. NADPH in cooperation with the plastid stroma may play an important regulatory role during the biosynthesis of divinyl and monovinyl protochlorophyllide a.
ChemInform Abstract: Diastereo‐ and Enantioselective Synthesis of Densely Functionalized Cyclohexanones via Double Michael Addition of Curcumins with Nitroalkenes. (2012)

Abstract By using the most effective combination of an organocatalyst and a base, the title reaction is carried out for the first time.
The chemistry involved in the preparation of a paint pigment. An experiment for the freshman laboratory (1976)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe chemistry involved in the preparation of a paint pigment. An experiment for the freshman laboratoryTerri L. Daines and Karen W. Morse Cite this: J. Chem. Educ. 1976, 53, 2, 117Publication Date (Print):February 1, 1976Publication History Received3 August 2009Published online1 February 1976Published inissue 1 February 1976https://doi.org/10.1021/ed053p117Request reuse permissionsArticle Views1033Altmetric-Citations3LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (1 MB) Get e-Alertsclose Get e-Alerts
Monitoring morphological changes in an arid zone by spaceborne images and aerial photography between 1945 - 2009; the Yamin Plateau, Israel (2010)

This research focuses on a geomorphic mapping of the Yamin Plateau in southern Israel which is part of the YaminRotem Syncline and covers about 200 km. This area has been restricted since the 1950s and therefore, provides a unique opportunity to study undisturbed geomorphic processes. Nowadays, the national nuclear waste depository is located in this area accepting waste from industrial factories, research institutes and hospitals. This is the main reason why environmental processes are of major interest in terms of landform changes in space and time.
Effect of urea and other organic substances on the ultrasonic absorption of protein solutions (1971)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTEffect of urea and other organic substances on the ultrasonic absorption of protein solutionsRaoul Zana, Jacques Lang, and Christian TondreCite this: J. Phys. Chem. 1971, 75, 3, 374–379Publication Date (Print):February 1, 1971Publication History Published online1 May 2002Published inissue 1 February 1971https://doi.org/10.1021/j100673a014RIGHTS & PERMISSIONSArticle Views51Altmetric-Citations16LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (847 KB) Get e-Alerts
Elastase and Suppressor Active Peptide Activity following Burn Injury (1988)

Proteolytic enzyme activity following trauma and inflammation plays a key role in the pathophysiology of injury. The precise mechanisms involved in the induction of protease release has not been determined. We show here that sera from burn patients with greater than 40% TBSA have significantly elevated levels of active elastase which correspond with significantly increased levels of suppressor active peptide (SAP) and suppression of neutrophil chemotaxis. The elastase inhibitory capacity of serum from burned or blunt trauma patients was within normal range, suggesting that the primary elastase inhibitor, alpha-1-proteinase inhibitor, is functionally active. Additionally, granulocytes exposed to suppressor active peptide in vitro resulted in a markedly elevated release of elastase into the culture supernatants. These data suggest that the suppressor peptide is capable of not only suppressing immune function but is also a potent mediator for the induction of proteolytic enzyme release from leukocytes.
Modeling Uncertainties in Performance of Object Recognition 1 (2012)

Efficient probability modeling is indispensable for uncertainty quantification of the recognition data. If the model assumptions do not reflect the intrinsic nature of data and associated random variables, then a strong performance measure will most likely fail to come up with a correct match for recognition. In this paper we propose the probability models for two kinds of data obtained with two distinct goals of recognition: identification and discovery. We consider both frequentisi and Bayesian approaches for drawing inferences from the data.
Neuroendocrinology in Physiology and Medicine (2000)

The cover depicts a montage oftyrosine hydroxylase immunoreactive neurons labe led with fluorescent dye CY2 in the hypothalamic arcuate nucleus and their axon terminals in the median eminence.
Regulation of tumor cell apoptotic sensitivity during the cell cycle (Review). (2000)

Understanding how current chemotherapeutic modalities induce apoptosis is critical to designing better anti-cancer agents. This review is concerned with how pharmacological agents induce tumor cell apoptosis in a cell cycle-dependent manner. Recent experiments demonstrate that expression of several apoptotic regulatory proteins (such as Bcl-2, Bax, p53, and Survivin) are differentially regulated according to the phases of the cell cycle. This cell cycle-dependent regulation in turn contributes to increased drug sensitivity in different phases of the cell cycle. It is therefore likely that the cell cycle-dependent expression of cell death proteins plays a role in regulating chemosensitivity and apoptotic commitment of human tumor cells.