gebhart/patrepeval huggingface dataset:
The 20 GHz spacecraft IMPATT solid state transmitter (1986)

The engineering development of a solid-state transmitter amplifier operating in the 20-GHz frequency range is described. This effort involved a multitude of disciplines including IMPATT device development, circulator design, multiple-diode circuit design, and amplifier integration and test. The objective was to develop a transmitter amplifier demonstrating the feasibility of providing an efficient, reliable, lightweight solid-state transmitter to be flown on a 30 to 20 GHz communication demonstration satellite. The work was done under contract from NASA/Lewis Research Center for a period of three years. The result was the development of a GaAs IMPACT diode amplifier capable of an 11-W CW output power and a 2-dB bandwidth of 300 MHz. GaAs IMPATT diodes incorporating diamond heatsink and double-Read doping profile capable of 5.3-W CW oscillator output power and 15.5% efficiency were developed. Up to 19% efficiency was also observed for an output power level of 4.4 W. High performance circulators with a 0.2 dB inserting loss and bandwidth of 5 GHz have also been developed. These represent a significant advance in both device and power combiner circuit technologies in K-band frequencies.
Simultaneous On-chip Surface Plasmon Resonance Measurement of Disease Marker Protein and Small Metabolite Combined with Immuno- and Enzymatic Reactions (2008)

Abstract Disease marker protein and a correction marker were simultaneously measured with a portable surface plasmon resonance (SPR) system and PDMS microchannel. Two gold films in the microchannel were modified with antibody and redox polymer containing horseradish peroxidase (HRP). Creatininase, creatinase, and sarcosine oxidase were immobilized in the upstream. We could measure glycoprotein, transferrin (MW: 75 kDa) and creatinine (MW: 113) both by SPR angle shifts caused by immuno- and redox reactions, indicating that urinary transferrin concentration could be normalized with creatinine concentration by single injection.
<title>Optical Pattern Recognition And Classification Invariant To Selectable Pattern Features</title> (1979)

A coherent optical method of performing pattern recognition has been studied which is invariant to selectable pattern features. Two examples of pattern features frequently encountered in pattern recognition tasks are scale and rotation. A recognition scheme which is invariant to these features is able to detect an object independent of its size and angular orientation. In our case, the recognition scheme not only is invariant to these specific features, but can also be used to measure them.
Mechanical Hybrid System Comprising a Flywheel and CVT for Motorsport and Mainstream Automotive Applications (2009)

<div class="htmlview paragraph">Hybrid drivetrain systems focusing on Kinetic Energy Recovery Systems (KERS) will be introduced in Formula 1 for the 2009 season with the clear intent of directing technical developments in motorsport that will have an impact to the key issue of fuel efficiency in road cars.</div> <div class="htmlview paragraph">The 2009 season specification defines a system that can recover, store and reapply 400kJ of energy per lap at a maximum rate of 60kW. In order to promote technical development, neither the type of system (be it electrical, mechanical, hydraulic, etc.), the weight of the system nor the strategy for reapplication of the recovered energy has been defined.</div> <div class="htmlview paragraph">Flybrid Systems LLP have developed a mechanical KERS utilising a high speed carbon filament flywheel and a Torotrak full-toroidal traction drive Continuously Variable Transmission for use both within F1 and motorsport but also for mainstream automotive applications.</div> <div class="htmlview paragraph">This paper describes the Formula 1 system and the development of road car systems covering the energy storage requirements, system efficiencies, energy savings and hence performance improvements.</div>
Surface Energy and Wetting Behaviour of Plasma Etched Porous SiCOH Surfaces and Plasma Etch Residue Cleaning Solutions (2009)

The removal of plasma etch residues by wet cleaning is an alternative or additional process to plasma processes, which are known to degrade low-k and ultralow-k dielectric materials. Besides Cu/low-k compatibility wetting is an important issue for wet cleaning. Surface energy of solid and liquid is the key to understand the wetting behaviour. In this study we examined the energetic character of plasma etched/stripped solid surfaces, etch polymers and several cleaning solutions by contact angle measurements. The results show, that variations of the etching process can heavily change the energetic character of the solid. Calculating the surface energies of solid and liquid provides the possibility to make a prediction if a cleaning liquid will wet the surface which has to be cleaned.
Comparison of a human T-cell lymphotropic virus type I strain from cerebrospinal fluid of a Jamaican patient with tropical spastic paraparesis with a prototype human T-cell lymphotropic virus type I (enzyme-linked immunosorbent assay/Southern blotting/lmmunoblotting/dementia) (2016)

The isolation and characterization of a hu- man T-cell lymphotropic retrovirus related to human T-cell lymphotropic virus type I (HTLV-I) from cerebrospinal fluid of a Jamaican patient with tropical spastic paraparesis is de- scribed. The virus isolate is a typical type C retrovirus as seen by electron microscopy and is related to prototype HTLV-I isolated from patients with adult T-cell leukemia but is not identical to this prototype HTLV-I as seen by restriction enzyme mapping. Human T-cell lymphotropic virus type I (HTLV-I) has been shown to be the etiological agent of tropical spastic para- paresis (TSP) in several parts of the world. We have com- pared a strain isolated from the cerebrospinal fluid of a Jamaican TSP patient with a prototype HTLV-I isolated from a patient with adult T-cell leukemia (ATL), by restriction enzyme mapping. TSP is a neurological disorder characterized by paraparesis and spasticity of the lower limbs, which is sometimes associated with posterior column and superficial sensory change. Endemic TSP occurs in diverse geographical regions (1), and recently IgG antibodies to HTLV-I were found in several Caribbean islands (2-4), South America (3, 5, 6), the Seychelles islands (7), parts of Africa (8), and also in patients in the more temperate climate of southern Japan, where an identical syndrome called HTLV- I-associated myelopathy (HAM) has been described (9). HTLV-I is a type C retrovirus that is endemic in the Caribbean and southern Japan and has been isolated from patients with
Estimating Equations for Parameters in Means and Covariances of Multivariate Discrete and Continuous Responses (1991)

Generalized estimating equations are introduced in an ad hoc fashion for the covariance matrix of a multivariate response. These equations are to be solved jointly with score equations from a generalized linear model for mean parameters. A class of quadratic exponential models is used to develop joint estimating equations for mean and covariance parameters in a more systematic fashion, and proposals for the use of such equations are developed. Comments on the relative merits of the ad hoc and model-based approaches to estimation are given and a regression illustration with a bivariate response is provided.
Synthesis, Characterization and Stat3 Inhibitory Properties of the Prototypical Platinum(IV) Anticancer Drug, [PtCl<sub>3</sub>(NO<sub>2</sub>)(NH<sub>3</sub>)<sub>2</sub>] (CPA-7) (2008)

This paper describes a reinvestigation of the literature concerning the synthesis and structural characterization of the platinum(IV)-based anticancer drug known as CPA-7 and believed to be the compound fac-[PtCl3(NO2)(NH 3)2]. CPA-7 has previously been extensively investigated for its ability to control tumor cell growth by inhibition of Stat3 signaling, but very little information is available concerning its synthesis or spectroscopic properties. A reproducible synthetic route is shown to produce an active material which is characterized by IR and (1)H, (14)N, (15)N, and (195)Pt NMR spectroscopy, and single crystal X-ray crystallography. The freshly prepared drug is obtained as a single isomer which may in fact be fac- or mer-[PtCl3(NO2)(NH3)2], but recrystallization resulted in a disordered crystal containing approximately equal amounts of the two geometric isomers.
Traffic Signs Recognition for Detailed Digital Maps Development and Driver Assistance Systems (2010)

Digital maps are considered as an additional sensor in many of the new ADAS, but these systems usually require a higher level of accuracy and detail of the maps. Among the important information that the maps should contain are the road geometry and traffic signs. In the first case, it is interesting to use accurate and fast methods for measurement. In the paper, a method based on a datalog vehicle is used. Satellite positioning and inertial measurements systems data are combined and dynamic behavior of the vehicle body is corrected measuring the movements of the suspension system. On the other hand, the information provided by traffic signs and route-guidance signs is extremely important for safe and successful driving. An automatic system that is capable of extracting and identifying these signs automatically would help human drivers enormously; navigation would be easier, allowing them to concentrate on driving the vehicle. A Computer Vision System is used to recognize and classify the different families of traffic signs combining it with GPS information to develop detailed and accurate digital maps. This sign recognition can also be used for real time warnings to the driver. Some results of test carried out in real situations are shown.
Practical PCR genotyping protocols for Plasmodium vivax using Pvcs and Pvmsp1 (2005)

These results indicate that the genotyping protocols presented can be useful in the assessment of in vivo drug efficacy clinical trials conducted in endemic areas and for epidemiological studies of P. vivax infections.
A Double-Blind, Randomized, Dose-Response Study Investigating the Pharmacodynamic and Pharmacokinetic Properties of the Long-Acting Insulin Analog Detemir (2005)

This study shows that insulin detemir provides a flat and protracted pharmacodynamic profile.
Recovery of the hypoxic ventilatory drive of rats from the toxic effect of hyperbaric oxygen. (1992)

Hyperbaric oxygen (HBO) exposure reduces the hypoxic ventilatory drive (HVD), probably by damaging the carotid bodies. The recovery of the HVD from HBO exposure was studied. The HVD was calculated from whole body plethysmographic recordings of the ventilatory response to greater than 85% and 2% O2 in N2 mixtures. Five groups of rats were exposed to HBO for 9 h at pressures of 1.9, 2.0, 2.1, 2.2, and 2.4 ATA, respectively. Each rat underwent three control measurements on different days prior to HBO exposures and then at various intervals following the exposure. Postexposure HVD was reduced to 28% of control values in the high PO2s. Ninety percent recovery of pre-exposure HVD was evident by 12-48 h although in some animals exposed to relatively low PO2s (1.9 and 2.0 ATA) HVD stabilized at a level lower than 100%. The recovery of the HVD in percent during the first 4 d following exposure can be expressed as an exponential function of the time from the termination of HBO: HVD = 28 + 72(1 - exp-0.053t) (t in hours). This information may be of importance in cases of repeated exposures to HBO where one tries to avoid cumulative damage to the carotid bodies, and in the care of the poorly oxygenated patient after HBO treatment.
Manganese kinetics demonstrated double contrast in acute but not in chronic infarction in a mouse model of myocardial occlusion reperfusion (2011)

Manganese (Mn(2+)) is considered as a specific MRI contrast agent that enters viable cardiomyocytes through calcium pathways. Compared to extracellular gadolinium based contrast agents, it has the potential to assess cell viability. To date, only information from the washout phase after recirculation has been used for the detection and characterization of myocardial infarct. This study showed for the first time that in a mouse model of coronary occlusion-reperfusion, Mn(2+) wash-in kinetics are different at 24 h after surgery (acute infarction) than at eight days after surgery (chronic infarction). A fast but transient entry of Mn(2+) into the acute infarct area led to a double contrast between infarct and remote areas, whereas entry of Mn(2+) into the chronic infarct area remained reduced compared to remote regions during both wash-in and washout phases. The main hypothesis is that extracellular space is largely enhanced in acute infarction due to cell membrane rupture and interstitial edema, whereas scar tissue is densely composed of collagen fibers that reduce the distribution volume of free Mn(2+) ions. In addition to its ability to accurately depict the infarct area during the redistribution phase, Mn(2+) is also able to discriminate acute versus chronic injury by the observation of double-contrast kinetics in a mouse model of ischemia reperfusion.
Molecular control of surface film compositions via pulsed radio-frequency plasma deposition of perfluoropropylene oxide (1991)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTMolecular control of surface film compositions via pulsed radio-frequency plasma deposition of perfluoropropylene oxideCharles R. Savage, Richard B. Timmons, and Jacob W. LinCite this: Chem. Mater. 1991, 3, 4, 575–577Publication Date (Print):July 1, 1991Publication History Published online1 May 2002Published inissue 1 July 1991https://pubs.acs.org/doi/10.1021/cm00016a005https://doi.org/10.1021/cm00016a005research-articleACS PublicationsRequest reuse permissionsArticle Views255Altmetric-Citations99LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Using GPS to Calibrate Loran-C (1990)

Various techniques for using simultaneous Global Positioning System (GPS)/Loran data to estimate the propagation uncertainties that limit the absolute accuracy of Loran-C are discussed. Significant improvements in the absolute accuracy of Loran can be achieved with very simple calibrations. The absolute accuracy of Loran in the Gulf of Maine without calibration is presented. The maximum and RMS absolute errors are between 700 and 500 m, depending on the choice of land model. Simple calibrations greatly improve the absolute accuracy of Loran. As shown, if the land conductivities are fixed a priori and a single parameter is optimized, the maximum and RMS absolute errors fall to around 250 and 60 m, respectively. Alternatively, land can be treated as a single conductivity which can be adjusted to reduce offshore additional secondary phase factor errors. The performance of this practice is summarized in tables which show maximum and RMS errors of around 300 to 100 m, respectively. >
Simultaneous renal allograft nephrectomy and allotransplantation (1970)

Retransplantation after failure of the first kidney is now a common occurrence. Usually, nephrectomy is done first and retransplantation is performed later. Hume 1 advises waiting at least 30 to 40 days between removal of the first transplant and placement of the second. However, with increased reliance on leukocyte typing, 2 a cadaver kidney may become available which matches a patient who is in good clinical condition, but is undergoing either acute or chronic rejection of his homograft. This offers the opportunity for retransplantation at the time of removal of the rejected graft, which spares the patient an additional operation and can provide him with a matched graft. Especially in cases of rare phenotypes, a matched graft might not become available for a long time and, therefore, should be used whenever possible. Recently, we have performed two renal allograft nephrectomies and immediate retransplantation, with good graft survival up to six months.
An integrated CNM architecture for multi-layer networks with simple SLA monitoring and reporting mechanism (2002)

In order to support a service level assurance (SLA) mechanism and make it visible, this paper proposes an efficient and simple SLA mechanism by extending the legacy CNM (customer network management) concept suitable for multilayer networks.
Invasion of endothelial and epithelial cells by strains of<i>Porphyromonas gingivalis</i> (2000)

Porphyromonas gingivalis is a periodontal pathogen that may also be involved in the pathogenesis of coronary heart disease. This microorganism has the ability to invade several cell lines. In this study, 26 different strains of P. gingivalis were tested for invasion of human umbilical vein endothelial cells and KB cells, a human oral epidermoid cell line. Abilities to invade both cell lines by an individual strain were similar, and their invasion efficiencies could be assembled into four groups: high, moderate, low and non-invasive. Of the 26 strains, only P. gingivalis AJW4 was non-invasive. Since the fimbriae are implicated as having a key role in invasion by this species, the presence of fimbriae on strain AJW4 was investigated. Using polymerase chain reaction (PCR), strain AJW4 was found to contain the fimA gene. Sequence analysis revealed it to be type IV according to the typing scheme developed by Amano et al. Further, fimA is transcribed in this strain as demonstrated by reverse transcription PCR and is expressed on the cell surface as visualized by negative staining and electron microscopy. The adherence+invasion of strain AJW4 was 38.7% of the most invasive strain (strain 381). However, the CFU ml(-1) of strain AJW4 recovered from within cells was 2.9% of strain 381. Even though strains AJW4 and W50 have the same type IV fimbriae, strain AJW4 is 8.9-fold more adhesive yet is internalized 170-fold less. These data indicate that the invasion efficiency of P. gingivalis is variable among the different strains, and that the expression of FimA is not sufficient for invasion.
Waste treatment and disposal. Progress report, May-October 1963 (1964)

Progress is reported on developments in waste treatment and disposal in terms of: high-level-waste calcination; low-level-waste treatment; engineering, economics, and safety evaluation; disposal in deep wells; disposal in natural salt formations; Clinch River study; fundamental studies of minerals; and White Oak Creek basin study. (B.O.G.)
Boosting the network performance via traffic reshaping (2002)

Traffic reshaping and its impact on providing deterministic guarantees of timely data delivery in a packet-switched virtual-circuit fixed-packet network are investigated. Two types of traffic smoothing are considered: global reshaping (when traffic on all network connections is smoothed) and local reshaping (when the traffic specification is changed only for a single connection). The conditions when reshaping is beneficial are derived and the optimal values of traffic model parameters are obtained. In particular, it is shown that, when one tries to minimize end-to-end delay bounds for leaky bucket constrained traffic, the traffic either should be made constant bit rate (CBR) or should not be reshaped at all. It is proven that changing the leaky bucket specification to the dual leaky bucket specification is always able to yield better timeliness guarantees and utilisation of network resources. Finally, local reshaping for the dual leaky bucket model is studied.
A Novel Platform-System to Study the Effects of a Vestibular Prosthesis on Non-Human Primate Postural Control (2017)

For the several millions of vestibular loss sufferers nationwide, daily-living is severely affected in that common everyday tasks, such as getting out of bed at night, maintaining balance on a moving bus, or walking on an uneven surface, may cause loss of stability leading to falls and injury. Aside from loss of balance, blurred vision and vertigo (perceived spinning sensation) are also extremely debilitating in vestibular impaired individuals. For the investigation of implants and prostheses that are being developed towards implementation in humans, non-human primates are a key component. The purpose of our study was to implement a distinctive balance platform-system to investigate postural responses for moderate to severe vestibular loss and invasive vestibular prosthesis-assisted non-human primates (rhesus monkeys) for test balance conditions of various task-difficulty levels. Although the need for vestibular rehabilitative solutions is apparent, postural responses for a broad range of peripheral vestibular function, and for various stationary and moving support conditions, have not been systematically investigated. The measurement system used in this research was unique in that it allowed us to conduct animal experiments, not investigated previously; such experiments are necessary towards the development on an invasive vestibular prosthesis to be used in humans suffering from vestibular loss. Our platform-system facilitated the study of rhesus monkey posture for stationary support surface conditions (i.e., quiet stance and head turns; more versus fewer footplate cues and large versus small base-of-support) and for dynamic support surface conditions (i.e., pseudorandom roll-tilts of the support surface). Further, the platform-system was used to systematically study postural responses that will serve as baseline measures for future vestibular-focused human and non-human primate posture studies.
An anti-infective synthetic peptide with dual antimicrobial and immunomodulatory activities (2016)

Antibiotic-resistant infections are predicted to kill 10 million people per year by 2050, costing the global economy $100 trillion. Therefore, there is an urgent need to develop alternative technologies. We have engineered a synthetic peptide called clavanin-MO, derived from a marine tunicate antimicrobial peptide, which exhibits potent antimicrobial and immunomodulatory properties both in vitro and in vivo. The peptide effectively killed a panel of representative bacterial strains, including multidrug-resistant hospital isolates. Antimicrobial activity of the peptide was demonstrated in animal models, reducing bacterial counts by six orders of magnitude, and contributing to infection clearance. In addition, clavanin-MO was capable of modulating innate immunity by stimulating leukocyte recruitment to the site of infection, and production of immune mediators GM-CSF, IFN-γ and MCP-1, while suppressing an excessive and potentially harmful inflammatory response by increasing synthesis of anti-inflammatory cytokines such as IL-10 and repressing the levels of pro-inflammatory cytokines IL-12 and TNF-α. Finally, treatment with the peptide protected mice against otherwise lethal infections caused by both Gram-negative and -positive drug-resistant strains. The peptide presented here directly kills bacteria and further helps resolve infections through its immune modulatory properties. Peptide anti-infective therapeutics with combined antimicrobial and immunomodulatory properties represent a new approach to treat antibiotic-resistant infections.