gebhart/patrepeval huggingface dataset:
Specification of a coprocessor for efficient access of data structures (1992)

Most of todays applications are developed using high-level programming languages, which allow information to be represented as various types of data structures. However, the support provided by current architectures for accessing these types of data is very limited, Previous research proposed the use of an access coprocessor (AP). The authors define the access coprocessor instruction set, specify the access-execute processors synchronization protocols and illustrate the working of the system with three benchmark algorithms. Their results show that substantial speedup in program execution-time can be achieved by EP-AP concurrency and the use of special instructions by the AP to efficiently access data structures.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Green tea catechins inhibit VEGF‐induced angiogenesis <i>in vitro</i> through suppression of VE‐cadherin phosphorylation and inactivation of Akt molecule (2003)

Studies have indicated that the consumption of green tea is associated with a reduced risk of developing certain forms of cancer and angiogenesis. The mechanism of inhibition of angiogenesis by green tea or its catechins, however, has not been well-established. Vascular endothelial (VE)-cadherin, an adhesive molecule located at the site of intercellular contact, is involved in cell-cell recognition during vascular morphogenesis. The extracellular domain of VE-cadherin mediates initial cell adhesion, whereas the cytosolic tail binding with beta-catenin is required for interaction with the cytoskeleton and junctional strength. Therefore, the cadherin-catenin adhesion system is implicated in cell recognition, differentiation, growth and migration of capillary endothelium. Using tube formation of human microvascular endothelial cells (HMVEC) in culture as an in vitro model of angiogenesis, we reported that vascular endothelial growth factor (VEGF)-induced tube formation is inhibited by anti-VE-cadherin antibody and dose-dependently by green tea catechins. We also demonstrated here that inhibition of tube formation by epigallocatechin gallate (EGCG), one of the green tea catechins, is in part mediated through suppression of VE-cadherin tyrosine phosphorylation and inhibition of Akt activation during VEGF-induced tube formation. These findings indicate that VE-cadherin and Akt, known downstream proteins in VEGFR-2-mediated cascade, are the new-targeted proteins by which green tea catechins inhibit angiogenesis.
KMS, ETC. (2002)

A general form of the "Wick rotation", starting from imaginary-time Green functions of quantum-mechanical systems in thermal equilibrium at positive temperature, is established. Extending work of H. Araki, the rôle of the KMS condition and of an associated anti-unitary symmetry operation, the "modular conjugation", in constructing analytic continuations of Green functions from real- to imaginary times, and back, is clarified. The relationship between the KMS condition for the vacuum with respect to Lorentz boosts, on one hand, and the spin-statistics connection and the PCT theorem, on the other hand, in local, relativistic quantum field theory is recalled. General results on the reconstruction of local quantum theories in various non-trivial gravitational backgrounds from "Euclidian amplitudes" are presented. In particular, a general form of the KMS condition is proposed and applied, e.g., to the Unruh- and the Hawking effects.
Wireless communication link at 300 GHz with up to 160 GBit/s (2020)

We demonstrate a wireless communication link in the 300 GHz band with a maximum single channel data rate of 160 GHz achieved with QAM32 modulation at 32GBaud. To the best of our knowledge this is the highest data rate reported for a single channel in this frequency band. The system employs a broadband optoelectronic emitter (PIN-PD) and a heterodyne detector.
Role of Type III Effector Secretion during Bacterial Pathogenesis in Another Kingdom (2004)

Complex and sophisticated mechanisms of bacterial pathogenesis in plants, which have similarities to the mechanisms used by bacterial pathogens of mammals, such as Yersinia and Salmonella spp. ([19][1], [76][2]), have recently been identified. Mammalian and plant pathogens can use type III secretion
Change in T2* relaxation time of Hoffa fat pad correlates with histologic change in a rat anterior cruciate ligament transection model (2015)

The Hoffa fat pad (infrapatellar fat pad) is a source of post-traumatic anterior knee pain, and Hoffa disease is a syndrome leading to chronic inflammation of the fat pad. Herein, change in T2* relaxation time of the fat pad was measured in a rodent anterior cruciate ligament transection (ACLX) model in order to (i) examine the causal relationship of anterior cruciate ligament (ACL) deficiency and Hoffa disease and (ii) demonstrate the feasibility of using T2* as an imaging biomarker to monitor disease progression. Three groups of male Sprague Dawley rats (n = 6 each group), received either (i) no intervention; (ii) sham surgery at the right knee; or (iii) right ACLX. T2* relaxation time was measured and histology was examined in the Hoffa fat pad after surgery. At 13 and 18 weeks after surgery, T2* values were significantly higher in the right fat pad than the left (p < 0.001) and significantly higher in the ACLX group than the control and sham groups (p < 0.001). Histology showed fibrosis and degeneration of adipocytes in the right knees of the ACLX group. We conclude that ACL deficiency and Hoffa disease are causally related and that MRI T2* value can serve as an imaging biomarker of Hoffa disease progression.
Per Oral Endoscopic Myotomy (POEM) for Achalasia: Excellent Long-term Safety, Efficacy and Durability in a Large Single-center 4-year Series (2013)

Purpose: POEM is the first NOTES procedure that appears poised to replace its surgical counterpart, Heller myotomy. In 2009, we performed the first POEM outside of Japan and first worldwide by a gastroenterologist. This study reports POEM outcomes from our 4-year prospective series with mean follow-up of 12.5 months. This is the largest single operator series by a gastroenterologist worldwide, with likely the largest number of post POEM patients (pts) assessed by objective tests for emptying and reflux, and a large proportion of challenging pts. Methods: Prospective IRB study including achalasia pts ≥ 18 years old without contraindication to POEM. Primary outcome: decrease in the Eckardt score to ≤ 3. Secondary outcomes: Adverse events (AEs), post POEM lower esophageal sphincter (LES) pressure, reflux symptoms, pH study, timed barium. Results: 66 achalasia pts had POEM from 10/2009-4/2013. Mean age 52 (18-93), 11% >80 years, 42% prior treatment (tx) [4 pneumatic dilation (PD), 10 suboptimal balloon dilation, 11 Botox, 3 Heller], 11 sigmoid. Mean esophageal diameter 5.3 cm (2.1-13.5), 8 pts stage III (6-8 cm), 12 pts stage IV (>8 cm/sigmoidization), 17 (26%) with severe comorbidities (ASA class III). Clinical success in 97% (64/66), 96% (54/56), 96% (47/49), 93% (27/29) of pts with minimum follow-up of 1, 3, 6 and 12 months, respectively. Two early pts (#3, #5) had tx failure (score>3) and underwent “salvage” PD with excellent sustained results (score 1). Significant decreases in Eckardt score (7.9 to 0.2; P<0.0001) and LES pressure (42.5-15.4 mmHg; P<0.0001) in 56 pts with clinical success. 100% and >50% emptying at 5 minutes on timed barium in 22/26 and 25/26 pts, respectively. No significant AEs: No deaths, no aborted POEMs or conversions, no ICU stay, no hospital stay >5 days, no surgical or IR interventions, no blood transfusions, and no POEM related readmissions. Minor technical AEs: mucosal flap injury 18 (27%), pneumoperitoneum requiring needle decompression 7 (10%), 1 small pneumothorax due to inadvertent air insufflation managed conservatively without chest tube. Reflux symptoms: 58% none, 27% rarely, 4% few times/week, 11% daily; well controlled medically. On follow-up EGD, 10/33 (30%) had erosive esophagitis (EE), 12/33 (36%) positive pH study (including the 10 EE pts). Conclusion: At a mean follow-up of over a year, POEM remains safe and effective even with inclusion of significant numbers of pts with severe achalasia (stage III/IV), advanced age, severe comorbidities and prior failed tx. We report likely the largest number of POEM pts with objective reflux and emptying tests. In contrast to subjective assessments, on objective tests, GERD appears to be at least as common as after Heller myotomy with fundoplication. Disclosure - Stavros Stavropoulos ERBE honorarium and Boston Scientific honorarium
Guanosine inhibits hepatitis C virus replication and increases indel frequencies, associated with altered intracellular nucleotide pools (2020)

Abstract In the course of experiments aimed at deciphering the inhibition mechanism of mycophenolic acid and ribavirin in hepatitis C virus (HCV) infection, we observed an inhibitory effect of the nucleoside guanosine (Gua). Here, we report that Gua and not the other standard nucleosides inhibits HCV replication in human hepatoma cells. Gua did not directly inhibit the in vitro polymerase activity of NS5B, but it modified the intracellular levels of nucleoside di- and tri-phosphate (NDPs and NTPs), leading to deficient HCV RNA replication and reduction of infectious progeny virus production. Changes in the concentrations of NTP or NDP modified NS5B RNA polymerase activity in vitro , in particular de novo RNA synthesis and template switching. Furthermore, the Gua-mediated changes were associated with a significant increase in the number of indels in viral RNA, which may account for the reduction of the specific infectivity of the viral progeny, suggesting the presence of defective genomes. Thus, a proper NTP:NDP balance appears to be critical to ensure HCV polymerase fidelity and minimal production of defective genomes. Author summary Ribonucleoside metabolism is essential for replication of RNA viruses. In this article we describe the antiviral activity of the natural ribonucleoside guanosine (Gua). We demonstrate that hepatitis C virus (HCV) replication is inhibited in the presence of increasing concentrations of this ribonucleoside and that this inhibition does not occur as a consequence of a direct inhibition of HCV polymerase. Cells exposed to increasing concentrations of Gua show imbalances in the intracellular concentrations of nucleoside-diphosphates and triphosphates and as the virus is passaged in these cells, it accumulates mutations that reduce its infectivity and decimate its normal spreading capacity.
Histological response to stent graft therapy. (1996)

Aortic dilation was not observed at 1 year after stent graft placement within AADs with patent side branches despite microscopic evidence of thrombus recanalization. A collagen-rich and elastin-poor neointima incorporated the entire stent graft.
Soluble ICAM‐1 serum levels in multiple sclerosis and viral encephalitis (1993)

Intercellular adhesion molecule ICAM-1 has a crucial role in the induction of an immune response and is instrumental in migration of T cells into inflamed tissue. We studied soluble ICAM-1 concentrations in patients with multiple sclerosis (MS), viral encephalitis, and other immunologic diseases, and compared results with those in other noninflammatory, nondemyelinating neurologic disorders as well as in healthy controls. MS patients with clinically active disease or enhancing lesions on MRI had elevated serum levels of soluble ICAM-1. Concentrations of soluble ICAM-1 were also increased in some patients with viral encephalitis. These findings raise the possibility that circulating ICAM-1 serves as a marker of acute inflammatory events in the brain and add to evidence implicating this adhesion molecule in the pathogenesis of MS.
Re: Upper Urinary Tract Urothelial Carcinoma With Loco-Regional Nodal Metastases: Insights From the Upper Tract Urothelial Carcinoma Collaboration (2011)

No AccessJournal of UrologyAdult Urology1 Aug 2011Re: Upper Urinary Tract Urothelial Carcinoma With Loco-Regional Nodal Metastases: Insights From the Upper Tract Urothelial Carcinoma Collaboration Samir S. TanejaM.D. Samir S. TanejaSamir S. Taneja More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(11)60380-7AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "Re: Upper Urinary Tract Urothelial Carcinoma With Loco-Regional Nodal Metastases: Insights From the Upper Tract Urothelial Carcinoma Collaboration." The Journal of Urology, 186(2), p. 454 © 2011 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 186Issue 2August 2011Page: 454 Advertisement Copyright & Permissions© 2011 by American Urological Association Education and Research, Inc.MetricsAuthor Information Samir S. Taneja More articles by this author Expand All Advertisement PDF downloadLoading ...
ChemInform Abstract: Formation of Ordered, Nonreconstructed CdTe(111) Surfaces Electrochemically. Studies by LEED and Auger Electron Spectroscopy. (1991)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Les tombeaux des papes limousins d'Avignon (1956)

Beaulieu Michèle. Les tombeaux des papes limousins d'Avignon. In: Bulletin Monumental, tome 114, n°3, année 1956. pp. 221-222.
LDV Measurements of Unsteady Flow in a Turbine Rotor (2002)

V2 time-averaged and mass-averaged relative velocity at rotor exit plane (plane 44, axial distance ZRT / Cax,RT = 1.459) The unsteady flow field in an axial-flow turbine rotor under low Reynolds number condition (Reout,RT = 3.60×10) was investigated experimentally using a laser Doppler velocimetry (LDV) system. Detailed measurements of the time-dependent unsteady distributions of velocity, flow angle, turbulence intensity and Reynolds stress were carried out at design operating condition. The obtained data was analyzed in terms of both absolute (stationary) frame of reference and relative (rotating) frame of reference. The effect of stator wake and secondary vortices on the flow field inside the rotor passage was clearly determined. X pitch-wise distance ZRT axial distance from rotor leading edge ZST axial distance from stator leading edge θ flow angle measured from axial direction vx’vz’ velocity correlation (Reynolds stress) Subscripts Abs absolute flow or absolute frame of reference in stator or rotor inlet value out stator or rotor outlet value Rel relative flow or relative frame of reference RT rotor value ST stator value Nomenclature Introduction Cax axial chord length With the new generation of small-sized gas turbine engines, low Reynolds number flows have become increasingly important. Blade Reynolds numbers for the turbine stage of small-sized gas turbines can drop below 10. At these low Reynolds number conditions, the boundary layer is dominated by laminar flow and is susceptible to flow separation, which is associated with increased loss and reduced performance. Recently, a lot of studies focused on the characteristics of turbine Re Reynolds number t time TRT rotor passing period in absolute frame TST stator passing period in relative frame Tu turbulence intensity V velocity V1 time-averaged and mass-averaged absolute velocity at stator exit plane (plane 1, axial distance ZST / Cax,ST = 1.075) 1 American Institute of Aeronaut 32nd AIAA Fluid Dynamics Conference and Exhibit 24-26 June 2002, St. Louis, Missouri AIAA 2002-2742 Copyright © 2002 by the American Institute of Aeronautics and Astronautics, Inc. All rights reserved. Test Section
A Large Dynamic Chamber for Characterizing Particulate and VOC Emissions (1996)

A dynamic chamber (8 m3) was designed and constructed for the investigation of particulate emissions from appliances and office equipment and their impact on indoor air quality. The supply air incorporated high efficiency particle filters to provide a near-zero particle background in a low turbulence flow. The flow rate could be varied from 2 to 80 m3/min. For testing operating appliances, such as vacuum cleaners, the dimensions of the chamber were chosen to allow an operator to use an appliance over a floor area of about 2 m2. The need for low particle backgrounds dictated that the chamber be operated in an overpressure mode, so that all leaks were from the inside and would only affect the total flow measurements. The flow converges into an outlet tube 20 cm in diameter where velocity and concentration measurements could be made in multiple ports. The chamber was furnished with interior lights and electrical outlets. Recently, the chamber has been modified with carbon filters on the inlet to allow for sampling of volatile organic compounds (VOCs), such as from floor wax. The filters remove the VOC background to a level below that detectable by the sorbent cartridges/analysis system used for sampling. The chamber has even been pressed into service as a small cleanroom for some operations that required its unique characteristics. The chamber has been successfully operated in both a closed-loop mode and in an open loop mode. The main advantage of the closed loop mode is that the backgrounds can be reduced to zero more quickly, but the disadvantage is that humidity and carbon dioxide concentrations grow because they are not removed by the filters. The chamber flow has been measured with helium trace gas with an interior stirring fan and been found to exhibit well-mixed decay characteristics, but when it is operated without the mixing fan, there are other tracer measurements that indicate a less-than-well-mixed flow. Chamber flow modeling is necessary to convert measured concentrations into source strengths, which are themselves usable in other indoor air quality models. Mathematical deconvolution of the time-dependent concentrations has also proved useful. Examples of vacuum cleaner and powder carpet cleaner emissions are presented to illustrate the types of emissions that can be measured in the chamber.
Use of Multiple Causes in the Classification of Deaths from Cardiovascular-Renal Disease (1955)

Use of Multiple Causes in the Classification of Deaths from Cardiovascular-Renal Disease Louis Weiner, Marjorie T. Bellows, Grace H. McAvoy, and Eli V. Cohen CopyRight https://doi.org/10.2105/AJPH.45.4.492 Published Online: August 29, 2011
<i>exo</i> ‐ <i>cis</i> ‐Bicyclo[3.3.0]Octane‐2‐Carboxylic Acid (2003)

Abstract exo ‐ cis ‐Bicyclo[3.3.0]octane‐2‐carboxylic acid reactant: 325 g. (3.0 moles) of cis,cis ‐1,5‐cyclooctadiene solvent: 3 l. of chloroform intermediate: 2‐(trichloromethyl)bicyclo[3.3.0]octane product: exo ‐ cis ‐bicyclo[3.3.0]octane‐2‐carboxylic acid
Prevalence and Risk Factors of Chronic Hepatitis B and C Virus Infection in the Immigrant Populations of the Twin Cities Metro Area, Minnesota, United States (2017)

Introduction: HBI-Minnesota is a non-profit organization that provides free viral hepatitis testing, screening for metabolic risk factors, education and linkages to care for underserved communities. Methods: Between February 2016 and April 2017, HBI-Minnesota screened 624 individuals in the Twin Cities (St. Paul and Minneapolis) for hepatitis B virus (HBV) and hepatitis C virus (HCV) infections. Participants also underwent serum glucose and plasma cholesterol testing. Results: Mean age was 52 + 10 years. Majority (56%) were males, and 64% were foreign-born (17% Vietnam, 17% Laos, 8% Burma, 22% Africa, and 36% others). A total of 4.2% of participants had evidence of chronic HBV. A total of 43% had no evidence of immunity against HBV and should be vaccinated. A total of 1.4% have positive HCV antibody. Table-1 summarizes risk factors of positive HBV or HCV testing. Elevated fasting serum glucose (>110 mg/dL) was seen in 7.8%, while 12.3% had elevated total cholesterol (>190 mg/dL).Table: Table. HBI-Minnesota Screening for Liver Disease summary descriptives table by groups of ‘Hepatitis'Conclusion: HBV and HCV infections are prevalent in the immigrant populations in the Twin Cities Metro Area of Minnesota. Education about viral hepatitis testing and vaccination should be encouraged and supported.
Force Analysis and Characterization of Polymer Actuators (2006)

There has been an increasing interest in conducting polymers, especially polypyrrole (PPy), as potential actuators for many cutting edge applications including micromanipulation and biomedical devices. Their performance needs to be assessed in terms of force and displacement outputs before they can be employed in practical devices. As part of an ongoing project to develop a robotic gripper for micromanipulation/fabrication applications, this study focuses on (i) deriving a mathematical model to predict the force produced at the tip of a trilayer bending type PPy-based actuator under input voltages, and (ii) experimentally verifying the model. The model has been used to estimate the force produced by a robotic finger consisting of a PPy actuator and a rigid link. The results presented show a good agreement between the experimental and predicted forces for two actuators with the dimensions of (10 mm times 1 mm times 0.17 mm) and (5 mm times 1 mm times 0.17 mm) with driving voltages up to 0.8 V
[Posttraumatic pseudoaneurysm of the zygomatic area]. (1987)

A case of post-traumatic false aneurysm of a segment of the zygomato-malar artery is used as a basis for a discussion of this fairly rare complication of facial injuries and the complementarity of angiographic examinations and surgical exploration findings.
Asymmetric mode scattering in strongly coupled photonic crystal nanolasers (2016)

We investigate the basic mechanism of nonlinear mode competition in two semiconductor-coupled nanocavities operating in the laser regime. For this, we study energy transfer between bonding (in-phase) and anti-bonding (out-of-phase) modes of the system formed by two strongly coupled photonic crystal nanolasers. We experimentally observe mode switching from the blue-detuned to the red-detuned mode as the pump power is increased. A semi-classical description in terms of mean-field equations allows us to explain this phenomenon as stimulated scattering due to carrier population oscillations in the cavities at the mode splitting frequency. We predict such asymmetrical mode interaction to be universal in arrays of optically coupled semiconductor micro and nanocavities.
Longitudinal Study of CSF Biomarkers in Patients with Alzheimer's Disease (2009)

Tau and Abeta42 in CSF seem to reflect the underlying disease state in both early and late stages of AD. The slight increase in tau over time observed in the patients with AD is modest when compared to the relatively large difference in absolute tau levels between AD patients and controls. Therefore, these markers maintain their usefulness as state markers over time and might serve as surrogate markers for treatment efficacy in clinical trials.
Lack of Nucleotide Sequence Relationship Among the Temperate Bacteriophage SPO2, <i>Bacillus subtilis</i> , and Virulent Bacteriophages β3 and β22 (1970)

Radiolabeled phage SPO2 fragments were tested for the abiity to form interspecies deoxyribonucleic acid (DNA) duplexes with DNA from Bacillus subtilis and from phages beta3 and beta22. No reassociation, above control values, occurred between the DNA of phage SPO2 and that of its host or either of the virulent B. subtilis phages. It appears that extensive nucleotide sequence similarities between portions of host and phage DNA species are not necessary for the formation of the lysogenic state. The thermal elution profile of reassociated SPO2 DNA exhibited a normal distribution, indicating no heterogeneity in base composition. This differs from temperate enterophages whose DNA molecules contain regions of differing base composition.