gebhart/patrepeval huggingface dataset:
Single photon sources from InP based colloidal quantum dots (2017)

CdSe based colloidal quantum dots are extensively studied for a variety of applications including the single photon emission at room temperature [1, 2]. While the blinking has been considerably reduced in CdSe quantum dots, the purity of single photon emission has been elusive at higher intensities due to the contribution of multiple excitons. We observe that the newly synthesized Cd-free InP based quantum dots have similar optical properties to CdSe. The broader ensemble spectra of InP was earlier believed due to the broader single dots but our characterization on the InP/ZnSe prove the inhomogeneity by the presence of narrow single dot spectra. The single quantum dots also exhibit strong antibunching (g <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> (0)<0.02) at intensities below and above the saturation level proving the nature of single quantum emitter and a two-level system. InP/ZnSe core/shell quantum dot has a type I energy level structure where both the charge carriers are confined in the core itself. The strong antibunching reveals that the probability of radiative recombination with more than one exciton is very low. We believe the stronger Auger rate of 70 ps is the preferred route for the multiple excitons, ultimately emission coming only from the single exciton. The presence of faster Auger process was earlier thought to be responsible for the presence of dark states leading to more blinking in the emission of the quantum dots [2]. But our characterization results on this quantum dot are novel which show suppressed blinking and also strong antibunching due to the efficient Auger process at the same time.
Studies on Grinding and Combustion Properties of Woody Biomass (2003)

The purpose of the present research and development is to develop technology for converting biomass resources into energy economically and with high ecciciency-specifically, technology for co-firing of woody biomass and coal at existing coal-fired power plants, which currently have high CO_2 emission rates.
Effects of Ammonium Polyphosphates on Yield<sup>1</sup> and Chemical Composition of Irrigated Corn (1970)

Abstract Irrigated corn ( Zea mays L.) grown on Zn‐deficient, slightly acid Cass fine sandy loam suffered from increasingly severe Zn deficiency when 40 kg/ha P (80 lb/A P 2 O 5 ) was applied in a band to the side and below the seed. Zinc deficiency was corrected in the presence of the banded P when Zn was supplied at the rate of 11.2 kg Zn/ha as ZnSO 4 . Banded applications of ammonium polyphosphate (APP) in the presence of inadequate Zn tended to induce more severe Zn deficiencies than did similar applications of monoammonium phosphate (MAP). When adequate Zn was supplied, the two forms of P produced comparable plant growth responses and grain yields. Yield depressions noted with the use of banded APP without adequate Zn were associated with higher plant P contents than when the plants were supplied with MAP. High levels of plant P were concomitant with low levels of Zn in the plants. Banded applications of P resulted in higher plant concentrations of P than did broadcast P applications and induced more severe Zn deficiencies. When Zn was limiting, grain yields tended to decrease with increasing P concentrations in young plant tissues. In the presence of adequate Zn concentration of P in young plant tissues was positively correlated with grain yields.
A Feasibility Study of Using HPC Cloud Environment for Seismic Exploration (2015)

Summary Seismic applications require High Performance Computing (HPC) to simulate the dynamics of complex models. Not a long ago, companies, research institutes, and universities used to acquire clusters of computers to maintain them on-premise. Recently, cloud computing has become an alternative for a subset of HPC applications, including seismic. This poses a challenge to the end-users, who have to decide whether they should run their applications on their local clusters or burst them to a remote cloud provider. In this paper, we present a feasibility study of using cloud for seismic processing, comparing its performance with a default on-premise HPC cluster. For that, an architecture for FWI as a service on cloud is proposed and the paper discusses also the possible financial benefits of cloud. Results indicate that cloud can be an interesting alternative to boost on-premise HPC clusters. It achieves similar or even lower turnaround time in comparison to HPC clusters, avoiding queue waiting time.
The effect of drug therapy without volume replacement in experimental traumatic shock. Part I. Phenoxybenzamine and dopamine. (1975)

The effect of phenoxybenzamine and dopamine on the respiratory and metabolic changes in experimental traumatic shock was examined in 45 rabbits. Phenoxybenzamine caused a more effective release of the peripheral vasoconstriction than dopamine. The effect of these drugs without similar restoration of blood volume was unfavourable. This should be borne in mind when the use of these drugs is meditated in clinical work.
Cytokeratin 75 expression in central, centrifugal, cicatricial alopecia – new observations in normal and diseased hair follicles (2009)

K75 expression is closely associated with the process of desquamation of the IRS. This process occurs prematurely (below the isthmus) in many follicles from patients with, but not without, CCCA. K75 expression highlights premature desquamation of the IRS in CCCA, but may not be directly involved in disease pathogenesis.
RP463:  A Stabilized Technetium-99m Complex of a Hydrazino Nicotinamide Derivatized Chemotactic Peptide for Infection Imaging (1999)

A HYNIC-conjugated chemotactic peptide (fMLFK-HYNIC) was labeled with (99m)Tc using tricine and TPPTS as coligands. The combination of fMLFK-HYNIC, tricine, and TPPTS with (99m)Tc produced a ternary ligand complex [(99m)Tc(fMLFK-HYNIC)(tricine)(TPPTS)] (RP463). RP463 was synthesized either in two steps, in which the binary ligand complex [(99m)Tc(fMLFK-HYNIC)(tricine)(2)] (RP469) was formed first and then reacted with TPPTS, or in one step by direct reduction of [(99m)Tc]pertechnetate with stannous chloride in the presence of fMLFK-HYNIC, tricine, and TPPTS. The radiolabeling yield for RP463 was usually >/=90% using 10 microg of fMLFK-HYNIC and 100 mCi of [(99m)Tc]pertechnetate. Unlike RP469, which decomposed rapidly in the absence of excess tricine coligand, RP463 was stable in solution for at least 6 h. [(99)Tc]RP463 was prepared and characterized by HPLC and electrospray mass spectrometry. In an in vitro assay, [(99)Tc]RP463 showed an IC(50) of 2 nM against binding of [(3)H]fMLF to receptors on PMNs. [(99)Tc]RP463 also induces effectively the superoxide release of polymorphonuclear leukocytes (PMNs) with an EC(50) value of 0.2 +/- 0.2 nM. The localization of RP463 in the infection foci was assessed in a rabbit infection model. RP463 was cleared from the blood faster than RP469 and was excreted mainly through the renal system. As a result of rapid blood clearance and increased uptake, the target-to-background ratios continuously increased from 1.5 +/- 0.2 at 15 min postinjection to 7.5 +/- 0.4 at 4 h postinjection. Visualization of the infected area could be as early as 2 h. A transient decrease in white blood cell count of 35% was observed during the first 30 min after injection of the HPLC-purified RP463 in the infected rabbit. This suggests that future research in this area should focus on developing highly potent antagonists for chemotactic peptide receptor or other receptors on PMNs and monocytes.
The LD activity profiles of single and group-housed male and female flies. (2015)

<p>Male and female control flies (<i>w<sup>1118</sup>/+</i>) were aged, entrained and assayed between the ages of 1 to 4-weeks. Flies were assayed singly or in large group activity monitors (10 per vial) for 48 hours under standard 12-hr lights on, 12-hr lights off (<b>LD</b>) conditions. Yellow and black bars indicate day (8:00am to 8:00pm) and night (8:00pm to 8:00am) time periods, respectively. Activity is presented as an average per individual fly. (<b>A-B</b>) The average activity or actogram profiles of single-housed WT (<i>w<sup>1118</sup>/+</i>) male and female flies, between 1 to 4-weeks of age. (<b>C-D</b>) The average activity profiles of group-housed male and female from 1 to 4-weeks of age. (<b>E-F</b>) The average activity levels of group-housed male and female flies (per fly) during day (ZT0-12), night (ZT12-24) and mid-dark (ZT15-21) time periods. * P ≤ 0.05, ** P ≤ 0.01 and *** P ≤ 0.001. See <b><a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0132768#pone.0132768.s007" target="_blank">S2 Fig</a></b> and <b><a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0132768#pone.0132768.s007" target="_blank">S2 Table</a></b> for additional information.</p>
Membrane Bound IgG on Erythroblasts in Pure Red Cell Aplasia following Thymectomy (1976)

A case of pure red cell aplasia appearing 6 months following thymectomy is reported in a 43-year-old man. Immunofluorescence studies of the patient's bone marrow have demonstrated the presence of membrane-bound IgG on the majority of erythroblasts and some mature erythrocytes. It is suggested that the IgG represents anti-erythroid autoantibodies. The number of Ig-bearing lymphocytes in peripheral blood was decreased as was the level of immunoglobulins indicating a B-lymphocyte deficiency. T-lymphocyte functions were without remarks. The patient was initially treated with corticosteroids and oxymetholone. He responded well to this therapy but relapsed 9 month later. Cyclophosphamide treatment was started and followed by a complete haematologic remission.
Fluid mechanics for chemical engineers (1999)

1 Introduction Part I Preliminaries 2 Fluid Statics 3 The Balance Equation and the Mass Balance 4 The First Law of Thermodynamics Part II Flows which are Practically One-Dimensional or can be Treated as Such 5 Bernoulli's Equation 6 Fluid Friction in Steady One-Dimensional Flow 7 The Momentum Balance 8 One-Dimensional High-Velocity Gas Flow Part III Some Other Topics, Which can be Viewed by the Methods of One-Dimensional Fluid Mechanics 9 Model Studies, Dimensional Analysis, and Similitude 10 Pumps, Compressors, and Turbines 11 Flow Through Porous Media 12 Gas-Liquid Flow 13 Non-Newtonian Fluid Flow in Circular Pipes 14 Surface Forces Part IV Two- and Three-Dimensional Fluid Mechanics 15 Two- and Three-Dimensional Fluid Mechanics 16 Potential Flow 17 The Boundary Layer 18 Turbulence 19 Mixing 20 Computational Fluid Dynamics, (CFD) Appendix A Tables and Charts of Fluid Properties, Pipe Dimensions and Flows, and High-Velocity Gas Flows Appendix B Derivations and Proofs Appendix C Equations for Two- and Three-Dimensional Fluid Mechanics Appendix D Answers to Selected Problems
Acute Efficacy of ECT in the Treatment of Major Depression in the Old-Old (1999)

Despite a higher level of physical illness and cognitive impairment, even the oldest patients with severe major depression tolerate ECT in a manner similar to that for younger patients and demonstrate similar or better acute response.
Luminosity Function of Faint Globular Clusters in M87 (2006)

We present the luminosity function to very faint magnitudes for the globular clusters in M87, based on a 30 orbit \textit{Hubble Space Telescope (HST)} WFPC2 imaging program. The very deep images and corresponding improved false source rejection allow us to probe the mass function further beyond the turnover than has been done before. We compare our luminosity function to those that have been observed in the past, and confirm the similarity of the turnover luminosity between M87 and the Milky Way. We also find with high statistical significance that the M87 luminosity function is broader than that of the Milky Way. We discuss how determining the mass function of the cluster system to low masses can constrain theoretical models of the dynamical evolution of globular cluster systems. Our mass function is consistent with the dependence of mass loss on the initial cluster mass given by classical evaporation, and somewhat inconsistent with newer proposals that have a shallower mass dependence. In addition, the rate of mass loss is consistent with standard evaporation models, and not with the much higher rates proposed by some recent studies of very young cluster systems. We also find that the mass-size relation has very little slope, indicating that there is almost no increase in the size of a cluster with increasing mass.
Route selection for QoS over Mobile IP (2007)

Influenced by the availability of powerful portable computers, and the expansion of Internet-based services, consumers demand mobile Internet. This implies supporting user mobility while sustaining network connectivity which in turn requires more sophisticated routing methods than simple static Internet protocol. Routing optimization is critical for the efficiency of mobile Internet as it directly impacts resource utilization in the network. On the other hand, while connected to the Internet, users want to enjoy real-time services. Granting quality of service for real-time multimedia applications is one of the major concerns for Internet Service Providers. In the mobile Internet context, as a result of a signalling conflict, providing quality of service declines in presence of routing optimisation. This conflict must be resolved to achieve efficient resource utilization in the networks and provide quality of service for real-time Internet-based services. This thesis presents a solution for resolving the aforementioned conflict. Initially a set of requirements are established for a new solution. The fundamental idea is developed based on exercising routing optimization according to quality of service requirements and network conditions. A new protocol architecture for Mobile IP (MIP) is built based on a cross-layer design technique. This design implies that a new data flow collects the necessary parameters in the network. This data is passed to a new entity in the network layer of the MIP protocol stack that inter-connects IP, routing, mobility and resource reservation protocols. Based on network conditions and the quality of service requirements the optimal path is selected over which the resources are reserved for the duration of the connection. The new solution named MIP with Routing Optimization and QoS (MIP-ROQS) removes the signalling conflict and furthermore, results in increased network performance. Simulation of this solution demonstrates reduction in application end-to-end delay and delay variation, improved core network by reducing the amount of control traffic and dropped traffic and improved access network by reducing its delay. Moreover, we integrate Multi Protocol Label Switching (MPLS) architecture and MIP-ROQS to take advantage of MPLS labelling mechanism to label the optimal path selected by MIP-ROQS for the duration of a session. This integration makes IP-in-IP tunnelling in data forwarding redundant. MPLS is used to switch packets and label the optimal path over which the resources are reserved. Using this approach, the transmission delay, and packet processing overhead are further reduced.
Gene Delivery: Nano‐Self‐Assembly of Nucleic Acids Capable of Transfection without a Gene Carrier (Adv. Funct. Mater. 34/2015) (2015)

On page 5445, Y.-W. Won, D. A. Bull, and co-workers show that Zn2+ is able to assemble nucleic acids into a nanocluster that is capable of spontaneous internalization into cells. Zn2+ shows superior gene transfection efficiency among the three divalent metal ions tested. Various endocytosis mechanisms are involved in the cellular uptake of the Zn/DNA cluster.
Coherence and phase techniques applied to wind tunnel acoustics (1977)

Measurements have been made of coherence and phase spectra for the acoustic field in a subsonic wind tunnel. The data are interpreted in terms of simple analytical models for propagating and diffuse noise fields, including the presence of uncorrelated noise signals. It is found that low frequency noise propagates upstream and downstream from the fan, with the noise in the test section arriving in the upstream direction. High frequency sound appears to be generated in the test section and propagates upstream and downstream. In the low frequency range, the ratio of diffuse to propagating energy is about 8 for all locations in the test section, diffuser, and settling chamber; the value of the ratio increases with frequency. Further analysis is required to describe in better detail the effects of reverberation and incoherent sources in a duct-like environment.
An electrical test method for MEMS convective accelerometers: Development and evaluation (2011)

In this paper, an alternative test method for MEMS convective accelerometers is presented. It is first demonstrated that device sensitivity can be determined without the use of physical test stimuli by simple electrical measurements. Using a previously developed behavioral model that allows efficient Monte-Carlo simulations, we have established a good correlation between electrical test parameters and device sensitivity. Proposed test method is finally evaluated for different strategies that privilege yield, fault coverage or test efficiency.
Association of hyperhomocysteinemia with left ventricular dilatation and mass in human heart (2010)

Hyperhomocysteinemia appears to be, at least in part, involved in a disproportional LV dilatation, where the ensuing hypertrophy is not sufficient to compensate for the increased wall stress. A potential mechanism is the hyperhomocysteinemia associated increase in oxidative stress that favors muscle fiber slippage.
Cilansetron: a new serotonergic agent for the irritable bowel syndrome with diarrhoea (2005)

Cilansetron is a novel serotonin type-3 (5-hydroxytryptamine; 5-HT) receptor subtype 3 (5-HT(3)) receptor antagonist currently being evaluated for the treatment of female and male patients with irritable bowel syndrome with diarrhoea predominance (IBS-D). 5-HT(3) receptor antagonists such as cilansetron have been shown to affect gastrointestinal motility. Whether cilansetron affects visceral sensation independent of effects on visceral compliance remains controversial. Results from two large, randomised, double-blind, placebo-controlled, parallel-group Phase III clinical trials of cilansetron in patients with IBS-D have recently been presented in abstract form. These studies found that cilansetron was more effective than placebo at improving overall, as well as individual symptoms, including abdominal pain and diarrhoea in female and male IBS-D patients. The most commonly reported side effect with cilansetron has been constipation and, in general, the drug has been well tolerated in clinical trials. Although rare, the most concerning side effect observed with cilansetron has been suspected ischaemic colitis. The event rate for suspected ischaemic colitis associated with cilansetron from clinical trials is 3.77 per 1000 person years of exposure. This rate appears to be greater than that expected in the IBS population and similar to that observed with alosetron, another 5--HT(3) receptor antagonist. All of the cases of suspected ischaemic colitis reported with cilansetron have resolved without serious sequelae. How issues surrounding the safety of cilansetron will affect the approval process in various countries remains to be determined. However, the risk-benefit of cilansetron is likely to be most favourable in patients with IBS-D who have failed to respond to conventional medical therapies. A detailed risk management plan and post-marketing surveillance programme will be required should this drug become available for the treatment of patients with IBS-D.
Reliability and low-frequency noise measurements of InGaAsP multiple quantum well buried-heterostructure lasers (2002)

Analysis of low-frequency noise characteristics is used to investigate the behavior of gain-coupled buried-heterostructure lasers. Devices which exhibit threshold current degradation during electrical and thermal overstress, as well as stable devices, are examined. In addition to examining the magnitudes of the optical and electrical noise as functions of current and frequency, the correlation between the electrical and optical noise is examined. It is shown that unreliable lasers exhibited white electrical and optical noises with negative correlation between them at threshold while the reliable devices did not. While the root cause of these characteristic noise differences is as of yet unknown, the present results suggest the potential utility of noise measurements as a means of predicting laser reliability and the development of low-cost screening techniques.
An integrated <i>in silico</i> immuno-genetic analytical platform provides insights into COVID-19 serological and vaccine targets (2020)

ABSTRACT Background The COVID-19 pandemic, caused by the SARS-CoV-2 virus, has a major global health and socio-economic burden. It has instigated the mobilisation of resources into the development of control tools, such as diagnostics and vaccines. The poor performance of some diagnostic serological tools has emphasised the need for up to date immune-informatic analyses to inform the selection of viable targets for further study. This requires the integration and analysis of genetic and immunological data for SARS-CoV-2 and its homology with other human coronavirus species to understand cross-reactivity. Methods We have developed an online “immuno-analytics” resource to facilitate SARS-CoV-2 research, combining an extensive B/T-cell epitope mapping and prediction meta-analysis, and human CoV sequence homology mapping and protein database annotation, with an updated variant database and geospatial tracking for >7,800 non-synonymous mutation positions derived from >150,000 whole genome sequences. To demonstrate its utility, we present an integrated analysis of SARS-CoV-2 spike and nucleocapsid proteins, both being vaccine and serological diagnostic targets, including an analysis of changes in relevant mutation frequencies over time. Results Our analysis reveals that the nucleocapsid protein in its native form appears to be a sub-optimal target for use in serological diagnostic platforms. The most frequent mutations were the spike protein D614G and nsp12 L314P, which were common (>86%) across all the geographical regions. Some mutations in the spike protein (e.g. A222V and L18F) have increased in frequency in Europe during the latter half of 2020, detected using our automated algorithms. The tool also suggests that orf3a proteins may be a suitable alternative target for diagnostic serologic assays in a post-vaccine surveillance setting. Conclusions The immuno-analytics tool can be accessed online ( http://genomics.lshtm.ac.uk/immuno ) and will serve as a useful resource for biological discovery and surveillance in the fight against SARS-CoV-2. Further, the tool may be adapted to inform on biological targets in future outbreaks, including potential emerging human coronaviruses that spill over from animal hosts.