gebhart/patrepeval huggingface dataset:
THE ASSOCIATION OF PERIODIC PARALYSIS AND HYPERTHYROIDISM IN JAPAN (1957)

ALTHOUGH periodic paralysis is a rare disorder, its association with hyperthyroidism has been reported by several investigators (1–15). In reviewing the literature, it was found that only about 30 such cases have been reported from the United States and Europe, whereas more than 70 cases have been reported from Japan. Possibly the association of these two disorders is less rare in Japan. As the Japanese reports were all concerned with relatively small numbers of patients with hyperthyroidism, the incidence of the association of these two disorders in Japan could not be estimated. In order to obtain a fairly good estimate, the incidence of periodic paralysis among 6,333 cases of hyperthyroidism operated upon in three thyroid hospitals in Japan was studied. These hospitals were located in different parts of country—Noguchi Hospital in Beppu, Kyushu (southern part of Japan), Kuma Hospital in Kobe (central part of Japan) and Ito Hospital in Tokyo (eastern part of Japan), so the study provided data on a cross section of Japanese patient populations.
Imaging presentation of pancreatic neuroendocrine neoplasms (2018)

Pancreatic neuroendocrine neoplasms (P-NENs) are the second most common solid pancreatic neoplasms. P-NENs have a wide range of imaging features presentations and they can be detected with typical and atypical imaging presentations. Typical and atypical appearances can be explained by pathologic correlations. P-NENs are generally hypervascular lesions, showing a typical enhancement behavior after contrast media injection during imaging methods, but they could also have different imaging features, creating some difficulty in differential diagnosis. For this reason, radiologists should be aware of different imaging presentations of these neoplasms. Radiological evaluation has a critical role in P-NENs identification, characterization, and staging of these neoplasms, especially in those cases in which surgery is the treatment of choice. The present paper shows, indicating the underlying pathologic correlations, typical and atypical presentations of NENs. KEY POINTS: • P-NENs have a wide range of imaging features presentations, typical and atypical. • Pathology could help in better understanding the typical P-NENs appearance at imaging. • P-NENs are generally hypervascular lesions. • Radiological evaluation has a critical role in P-NENs identification and management. • Radiologists should know every type of different imaging presentation of P-NENs to better diagnose these kinds of lesions.
Laboratório de Vigilância Sanitária: segurança sanitária na história da saúde pública (2014)

Datas comemorativas de instituições e cidades são interpretações históricas e são motivo de homenagens, celebrações e, oportunamente, de reflexões críticas.1o de março de 1565 ou 20 de janeiro de 1567. As duas datas já foram marcos de celebração da cidade de São Sebastião do Rio de Janeiro. Entretanto, a partir de 1960, essa cidade instituiu o seu aniversário em março de 1565 e assim, está comemorando, neste ano de 2015, seus 450 anos.Pensando nas cidades e no desafio dos seus projetos civilizatórios, iniciamos este editorial da revista Visa em Debate, com essa analogia comemorativa. Destacamos o nosso labo-ratório de vigilância sanitária – o Instituto Nacional de Controle de Qualidade em Saúde, INCQS – e a perspectiva de, ao longo do próximo mês, abrirmos as festividades que ocorrerão durante todo o período, de setembro de 2015 até setembro de 2016, comemorando os 35 anos de sua fundação. Lembrando que é a instituição mantenedora dessa revista.PARABÉNS AO INCQS!
Depletion of topoisomerase II in isolated nuclei during a glucose-regulated stress response. (1989)

Conditions, such as anoxia or glucose starvation, which induce the glucose-regulated set of stress proteins also lead to resistance to adriamycin (J. Shen, C. Hughes, C. Chao, J. Cai, C. Bartels, T. Gessner, and J. Subjeck, Proc. Natl. Acad. Sci. USA 84:3278-3282, 1987) and etoposide. We report here that chronic anoxia, glucose starvation, 2-deoxyglucose, the calcium ionophore A23187, glucosamine, ethylene glycol-bis(beta-aminoethyl ether)-N,N,N',N'-tetraacetic acid (EGTA), and tunicamycin (all specific inducers of the glucose regulated system) lead to a rapid and selective depletion of topoisomerase II from isolated nuclei of Chinese hamster ovary cells. This effect precedes a decline in tritiated thymidine incorporation and a redistribution of cells from S into G1/G0. The depletion of the enzyme is not accompanied by a decline in mRNA levels. We have also examined the mutant Chinese hamster K12 cell line which is temperature sensitive for expression of glucose-regulated proteins. When nuclei were isolated from K12 cells incubated at the nonpermissive temperature, a loss of topoisomerase II was again observed in congruence with the expression of stress proteins and cellular resistance to etoposide. These changes were not obtained in parental Wg1A cells incubated at the same temperature. These studies indicate that topoisomerase II is highly sensitive to glucose-regulated stresses and that its depletion from the nucleus, with the associated changes in cell cycle parameters, may represent general characteristics of the glucose-regulated state. Since anoxia and glucose starvation can occur during tumor development, this pathway for expression of drug resistance may have clinical ramifications.
Agility through Information Sharing: Results Achieved in a Production Setting (1997)

As organizations seek to improve their competitive position by responding effectively to the increasing rate of change in the market place, the need for agile enterprises and agile manufacturing has come to the forefront In this paper we examine the essential role that informa tion sharing plays in enabling the agile manufacturing of complex products The principle goal of an agile manufacturing interface is to provide the information sharing infrastructure necessary to enable the formation of virtual organizations and to provide them with the robust DFx mechanisms they need in order to develop high quality products in a timely, cost effective manner Results achieved from the implementation of an agile manufacturing interface in a production environment are highlighted These results include a 10 x reduction in the cycle-time required to go from design to manufacturing set-up, and a reduction in the rework for complex Printed Circuit Assemblies of up to 80%
A Novel Multi-Exponential Function-based Companding Technique for Uniform Signal Compression over Channels with Limited Dynamic Range (2010)

A Novel Multi-Exponential Function-based Companding Technique for Uniform Signal Compression over Channels with Limited Dynamic Range Companding, as a variant of audio level compression, can help reduce the dynamic range of an audio signal. In analog (digital) systems, this can increase the signal-to-noise ratio (signal to quantization noise ratio) achieved during transmission. The μ-law algorithm that is primarily used in the digital telecommunication systems of North America and Japan, adapts a companding scheme that can expand small signals and compress large signals especially at the presence of high peak signals. In this paper, we present a novel multi-exponential companding function that can achieve more uniform compression on both large and small signals so that the relative signal strength over the time is preserved. That is, although larger signals may get considerably compressed, unlike μ-law algorithm, it is guaranteed that these signals after companding will definitely not be smaller than expanded signals that were originally small. Performance of the proposed algorithm is compared with μ-law using real audio signal, and results show that the proposed companding algorithm can achieve much smaller quantization errors with a modest increase in computation time.
Prostate-specific membrane antigen–directed nanoparticle targeting for extreme nearfield ablation of prostate cancer cells (2017)

Almost all biological therapeutic interventions cannot overcome neoplastic heterogeneity. Physical ablation therapy is immune to tumor heterogeneity, but nearby tissue damage is the limiting factor in delivering lethal doses. Multi-walled carbon nanotubes offer a number of unique properties: chemical stability, photonic properties including efficient light absorption, thermal conductivity, and extensive surface area availability for covalent chemical ligation. When combined together with a targeting moiety such as an antibody or small molecule, one can deliver highly localized temperature increases and cause extensive cellular damage. We have functionalized multi-walled carbon nanotubes by conjugating an antibody against prostate-specific membrane antigen. In our in vitro studies using prostate-specific membrane antigen-positive LNCaP prostate cancer cells, we have effectively demonstrated cell ablation of >80% with a single 30-s exposure to a 2.7-W, 532-nm laser for the first time without bulk heating. We also confirmed the specificity and selectivity of prostate-specific membrane antigen targeting by assessing prostate-specific membrane antigen-null PC3 cell lines under the same conditions (<10% cell ablation). This suggests that we can achieve an extreme nearfield cell ablation effect, thus restricting potential tissue damage when transferred to in vivo clinical applications. Developing this new platform will introduce novel approaches toward current therapeutic modalities and will usher in a new age of effective cancer treatment squarely addressing tumoral heterogeneity.
Scanning, standoff TDLAS leak imaging and quantification (2017)

This paper reports a novel quantitative gas plume imaging tool, based on active near-infrared Backscatter Tunable Diode Laser Absorption Spectroscopy (b-TDLAS) technology, designed for upstream natural gas leak applications. The new tool integrates low-cost laser sensors with video cameras to create a highly sensitive gas plume imager that also quantifies emission rate, all in a lightweight handheld ergonomic package. It is intended to serve as a lower-cost, higherperformance, enhanced functionality replacement for traditional passive non-quantitative mid-infrared Optical Gas Imagers (OGI) which are utilized by industry to comply with natural gas infrastructure Leak Detection and Repair (LDAR) requirements. It addresses the need for reliable, robust, low-cost sensors to detect and image methane leaks, <i>and to quantify leak emission rates</i>, focusing on inspections of upstream oil and gas operations, such as well pads, compressors, and gas plants. It provides: 1) Colorized quantified images of path-integrated methane concentration. The images depict methane plumes (otherwise invisible to the eye) actively interrogated by the laser beam overlaid on a visible camera image of the background. The detection sensitivity exceeds passive OGI, thus simplifying the manual task of leak detection and location; and 2) Data and algorithms for using the quantitative information gathered by the active detection technique to deduce plume flux (i.e. methane emission rate). This key capability will enable operators to prioritize leak repairs and thereby minimize the value of lost product, as well as to quantify and minimize greenhouse gas emissions, using a tool that meets EPA LDAR imaging equipment requirements.
Primary Carbon–Nitrogen Bond Scission and Methyl Dehydrogenation across a WW Multiple Bond (2010)

It takes two: A WW triple bond provides four electron equivalents to activate an amido CN bond and dehydrogenate a methyl group to produce a bridging methylidyne WV–WV complex (see picture: W green, C blue, N pink, O red, H black). Two detectable intermediates provide insight into this unusual sequence of bond ruptures.
Kinetic investigation on the curing of phenol-furfural resin by differential scanning calorimetry (1987)

Curing reactions of phenol-furfural (PFu) resin with hexamethylene tetramine (Hexa) have been studied by differential scanning calorimetry technique both dynamically as well as isothermally. The curing exotherms obtained have been analyzed to derive the kinetic parameters associated with the curing process. The effect of the concentration of hexa and the temperature on the curing characteristics have been investigated. The optimum concentration of hexa and the optimum temperature for curing are observed to be 12% and 160°C, respectively.
Josephson effect in an undergraduate laboratory (1978)

Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter Facebook Reddit LinkedIn Tools Icon Tools Reprints and Permissions Cite Icon Cite Search Site Citation G. Stroink, C. Purcell, B. Blackford; Josephson effect in an undergraduate laboratory. American Journal of Physics 1 April 1978; 46 (4): 424–425. https://doi.org/10.1119/1.11300 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAmerican Association of Physics TeachersAmerican Journal of Physics Search Advanced Search |Citation Search
Localization and Age-Related Changes in Cytochrome P450 Expression in APA Hamster Livers. (2000)

To establish the baseline data, age-related changes and the regional expression of the hepatic P450 isozymes in Syrian hamsters of the APA strain at 3, 6, 12, 18 months old were examined by immunological techniques. Immunohistochemical analysis of liver serial sections revealed that the midzonal and perivenous regions (zones 2 and 3, respectively) were stained with the anti-rat CYP1A1/2, 2B1/2 and 2E1 antibodies. These three antibodies most intensely stained the hepatocytes around the central vein. An anti-rat CYP3A2 staining section had a staining pattern with equally intense reactions in zones 2 and 3. On the other hand, CYP2C6, 2C11 and 4A1 were distributed diffusely throughout the hepatic acinus. There was no age-related difference in the expression pattern of any of the P450 isozymes examined. Total P450 content had a peak at 6 months of age and decreased to 60% of that level thereafter. Western-blot analysis revealed that the peak expressions of the isozymes detected with anti-rat CYP1A1/2, 2C6, 2E1 and 3A2 antibodies were observed in 6-month-old hamsters and declined in older ones. The CYP2B and 2C11 content reached the maximum at the age of 6 months and maintained almost the same level thereafter. The CYP4A level did not change from 3 to 6 months, and then declined to about 40% of the younger level at 12 and 18 months of age. These results suggest that the hepatic P450 isozymes of APA hamsters have region-specific expressions and most isozymes have their peaks of expression at 6 months of age, which differs from the patterns for rat P450.
Equivariant acyclic maps (1997)

In this paper we apply a recently developed new version of the Bredon-Illman cohomology theory to obtain an equivariant analogue of a result of Kan and Thurston, which implies that a connected CW-complex has the homotopy type of a space obtained by applying the plus construction of Quillen to certain Eilenberg-Mac Lane spaces.
Bundled hollow-optical fiber for delivery of 30-MW peak power Nd:YAG laser pulses (2006)

A bundled hollow waveguide, composed of 37 Ag-hollow fibers, was designed and fabricated to deliver high peak-power Q-Switched Nd:YAG laser pulses. The input end of the fibers are directly radiated by the laser beam without using a lens to remove an air-breakdown effect. Output peak-power up to 24 MW at the fundamental-mode was observed without any damages in the fibers. Output beam profiles from the waveguide were also examined and we observed no degradation in the beam quality at straight and bent positions.
Cannabis and Health (1977)

Book Review| February 01 1977 Cannabis and Health Cannabis and Health. J. D. P. GRAHAM. Academic PressLondon, New York and San Francisco 1976, pp. 481, £14.50 R. G. PERTWEE R. G. PERTWEE Search for other works by this author on: This Site PubMed Google Scholar Author and article information Publisher: Portland Press Ltd Online ISSN: 1470-8752 Print ISSN: 0300-5127 © 1977 Biochemical Society1977 Biochem Soc Trans (1977) 5 (1): 334–335. https://doi.org/10.1042/bst0050334a Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn Email Cite Icon Cite Get Permissions Citation R. G. PERTWEE; Cannabis and Health. Biochem Soc Trans 1 February 1977; 5 (1): 334–335. doi: https://doi.org/10.1042/bst0050334a Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsBiochemical Society Transactions Search Advanced Search This content is only available as a PDF. © 1977 Biochemical Society1977 Article PDF first page preview Close Modal You do not currently have access to this content.
Rumilly (Robert). — Histoire des Acadiens (1957)

Le Blant Robert. Rumilly (Robert). — Histoire des Acadiens. In: Revue d'histoire des colonies, tome 44, n°155, deuxième trimestre 1957. p. 251.
Correction to Ionically Gelled Alginate Foams: Physical Properties Controlled by Operational and Macromolecular Parameters (2013)

ADVERTISEMENT RETURN TO ISSUEPREVAddition/CorrectionORIGINAL ARTICLEThis notice is a correctionCorrection to Ionically Gelled Alginate Foams: Physical Properties Controlled by Operational and Macromolecular ParametersTherese Andersen*, Jan Egil Melvik, Olav Gåserød, Eben Alsberg, and Bjørn E. ChristensenCite this: Biomacromolecules 2013, 14, 5, 1710Publication Date (Web):April 12, 2013Publication History Published online12 April 2013Published inissue 13 May 2013https://pubs.acs.org/doi/10.1021/bm400411xhttps://doi.org/10.1021/bm400411xcorrectionACS PublicationsCopyright © 2013 American Chemical Society. This publication is available under these Terms of Use. Request reuse permissions This publication is free to access through this site. Learn MoreArticle Views355Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail PDF (728 KB) Get e-Alertsclose Get e-Alerts
The Performance of Toy Sunglasses and Children's Sunglasses (1985)

AbstractABSTRACT: Australian Standard 1067‐1983 deals with sunglasses. Sunglasses labelled as toys and not complying with dimension requirements in AS1067 are not covered by the standard. This paper deals with the compliance of children's sunglasses with the standard and compares the performance of children's sunglasses with those sold as toys. First, we could find no pair of sunglasses, toy or children's which met the standard. Second, the reasons for failure were similar in the two categories. Third, we suggest amendments to the requirements for children's sunglasses.Key words: SunglassesChildrenEye protection
Selective reductions. XV. Reaction of diborane in tetrahydrofuran with selected organic compounds containing representative functional groups (1970)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSelective reductions. XV. Reaction of diborane in tetrahydrofuran with selected organic compounds containing representative functional groupsHerbert Charles Brown, Peter Heim, and Nung Min YoonCite this: J. Am. Chem. Soc. 1970, 92, 6, 1637–1646Publication Date (Print):March 1, 1970Publication History Published online1 May 2002Published inissue 1 March 1970https://pubs.acs.org/doi/10.1021/ja00709a037https://doi.org/10.1021/ja00709a037research-articleACS PublicationsRequest reuse permissionsArticle Views1934Altmetric-Citations123LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Analysis of RAKE receiver in W-CDMA systems with downlink beamforming (2002)

This paper presents an analysis of a RAKE receiver in a W-CDMA downlink. The base station employs transmit beamforming, while each user employs R-finger RAKE receiver under selective fading channels. Spreading sequences are composed of Walsh codes and a common long code based on 3GPP standardization. We derive an exact expression for the instantaneous signal-to-interference-plus-noise ratio (SINR) at the output of the RAKE receiver. In the derivation process, the effect of spreading sequences, downlink beamforming, and the RAKE receiver are taken into account. Simulation examples for a 4-finger RAKE receiver are given to verify the derived expression. Our expression can be applied to evaluate transmit beamforming as well as to evaluate the performance of the RAKE receiver.