gebhart/patrepeval huggingface dataset:
A Review of Theoretical and Clinical lssues in Limb Apraxia (2000)

This paper was developed to review recent advances in the study of limb apraxia in order to further understand the nature of this disorder and possible approaches to its interventions. The following issues surrounding research on this area that are of theoretical relevance and practical importance were addressed: (1) a theoretical model that would guide research into limb apraxia; (2) assessment and analysis of error types involving observational descriptions of error patterns, manifestation of laterality effects of brain lesions, and kinematic analysis of spatio-temporal deficits; (3) the pathological significance of body part as objects (BPO) and its relationship with limb apraxia; and (4) remediation. Implications for future research and clinical practice are provided.
RAMAN SPECTROMETRY FOR DETECTION OF VENOUS AND ARTERIAL AIR EMBOLISM (1993)

Department of Anesthesia, Milton S. Hershey Medical Center, Penn State University College of Medicine, Hershey, Pa 17033
The Burns Unit in Copenhagen: I.<i>Principles of Treatment</i> (1968)

In the municipality of Copenhagen the treatment of burns has been centralized for more than 100 years, first in a dermatological department, later in a department of general surgery, and from 1961 in a separate Burns Unit. This Unit accommodates 16 patients. Its layout and staffing are described. The principle of treatment is exposure, before as well as after grafting, if done. The therapeutic procedure is described in detail, and the principles of general treatment, antibiotic and antishock therapy are reviewed. Up to 1964 major burns were treated by repeated excisions and grafting procedures. After 1964, total excision is performed on the 14th day postburn. During the same operation, all defects are covered with autografts, if necessary also with homografts. Energetic physiotherapy is employed, and the haemoglobin level is maintained by repeated transfusions.
Medical Castration Using the Investigational Oral GnRH Antagonist TAK-385 (Relugolix): Phase 1 Study in Healthy Males (2015)

Oral TAK-385 (40-180 mg/d) was well tolerated and effectively lowered testosterone in healthy men. Planned phase 2 doses in men with hormone-sensitive prostate cancer are 80 and 120 mg/d.
Continuous neonatal blood gas monitoring using a multiparameter intra-arterial sensor (1999)

Continuous MPIAS ABG monitoring is an exciting development, with the potential to reduce blood transfusions and improve ABG homeostasis.
Endogenous Anti-Inflammatory Very-Long-Chain Dicarboxylic Acids: Potential Chemopreventive Lipids (2018)

In a paradigm shift, cancer research efforts are being dedicated to the discovery of chemopreventive agents. The goal of this approach is to delay or prevent the progression of augmented cell division to established cancer. Research has focused on dietary supplements, drugs, and endogenous lipids that possess anti-inflammatory properties. We undertook a lipidomics analysis of potential endogenous anti-inflammatory/anti-proliferative lipids in human plasma. We performed high-resolution mass spectrometric lipidomics analyses of plasma samples from controls and patients with colorectal, kidney, pancreatic, glioblastoma, and breast cancers. We present evidence that endogenous very-long-chain dicarboxylic acids (VLCDCA) are anti-inflammatory lipids that possess chemopreventative properties. In a family of VLCDCAs, we characterized VLCDCA 28:4, which is decreased in the plasma of patients with colorectal, kidney, and pancreatic cancers. The structure of this biomarker was validated by derivatization strategies, synthesis of the analytical standard, and tandem mass spectrometry. Our data suggest that VLCDCA 28:4 may be a useful blood biomarker for a number of cancers and that resupplying this lipid, via a prodrug for example, may offer a new anti-inflammatory therapeutic strategy for delaying or preventing the progression of cancer and other inflammatory diseases.
Continuous validation of load test suites (2014)

Ultra-Large-Scale (ULS) systems face continuously evolving field workloads in terms of activated/disabled feature sets, varying usage patterns and changing deployment configurations. These evolving workloads often have a large impact, on the performance of a ULS system. Hence, continuous load testing is critical to ensuring the error-free operation of such systems. A common challenge facing performance analysts is to validate if a load test closely resembles the current field workloads. Such validation may be performed by comparing execution logs from the load test and the field. However, the size and unstructured nature of execution logs makes such a comparison unfeasible without automated support. In this paper, we propose an automated approach to validate whether a load test resembles the field workload and, if not, determines how they differ by compare execution logs from a load test and the field. Performance analysts can then update their load test cases to eliminate such differences, hence creating more realistic load test cases. We perform three case studies on two large systems: one open-source system and one enterprise system. Our approach identifies differences between load tests and the field with a precision of >75% compared to only >16% for the state-of-the-practice.
The Addition of 2-Oxido-2-cyclopenten-1-ylium to Some Olefins and Dienes in 2,2,2-Trifluoroethanol (2001)

The title reaction has been studied with 2-methoxypropene, (E)-cyclooctene, ethoxyethene, 1,3-cyclopentadiene, 3-methylenecyclohexene, styrene and isoprene as the olefinic substrates. This sequence is one of decreasing reactivity of the substrates towards 2-oxido-2-cyclopenten-1-ylium (1) if [4 + 3] cycloaddition (the prevailing reaction in the case of cyclopentadiene and isoprene) is ignored. This reactivity encompasses: (a) the formation of intermediate 1,5-dipoles, which in the majority of cases give rise to a multitude of products including many of higher molecular mass, and (b) two types of ene reactions, dubbed “ene-type 1” and “ene-type 2”. Type 1, in which the migrating hydrogen atom is abstracted from 1, is ubiquitous (except with 2-methoxypropene) but is always a minor reaction; type 2, in which the migrating hydrogen atom is transferred to 1, was encountered only in the cases of 3-methylenecyclohexene, in which it is a major reaction path, and isoprene. Both types were found to be slightly concerted. In this context, we observed an effect which we have dubbed “dipolar diversion of a concerted reaction”. In general, those substrates incapable of forming [4 + 3] cycloadducts gave complicated mixtures, with the exception of two compounds, which were found to give one predominant product with 1. The first of these is the trans-fixed 1,3-diene 3-methylenecyclohexene, which gave the ene-type 2 adduct 10d1, while the second is the most nucleophilic substrate, 2-methoxypropene, which gave a mixture of four adducts (two pairs of epimers), all of which gave the diketone 17 on hydrolysis.
[A relative bioavailability study of 2 oral formulations of omeprazole after their administration in repeated doses to healthy volunteers]. (1999)

To determine the relative bioavailability of Ulceral (study formula) with respect to Losec (reference standard formula) and establish their bioequivalence daily doses of 20 mg of omeprazole were given during 5 consecutive days to 24 healthy volunteers. No significant differences were observed in the area under the curve (AUC0-t), a parameter directly related to the inhibition of acid secretion induced by omeprazole. The confidence interval of 90% for the difference between the two formulations for AUC0-t was within the interval of acceptance (0.80-1.25). The confidence interval for the difference between the two formulations for Cmax were also within the range of acceptance (0.70-1.43). In relation to the time for achieving (Cmax (tmax), the difference between the two formulations and the confidence interval of 95% for the tmax was 0.75 (-0.5-1.75) h indicating that no significant differences were observed between the two treatments. This study confirms the bioequivalence of Ulceral with the standard reference formulation as well as the tolerability of the two formulae.
Evaluating Medication Adherence: Which Measure Is Right for Your Program? (2000)

OBJECTIVE:, Medication-adherence programs are increasingly important to managed care organizations. This review discusses the strengths and limitations of medication-adherence measurement techniques, including biological markers, pill counts, electronic monitoring devices, patient surveys, and prescription claims data. Specific tools for measuring med- ication adherence using prescription claims data are defined and demonstrat- ed. The process of selecting an appropri- ate tool is discussed.
DIVERSITY IN THE GENUS <i>SKELETONEMA</i> (BACILLARIOPHYCEAE): III. PHYLOGENETIC POSITION AND MORPHOLOGICAL VARIABILITY OF <i>SKELETONEMA COSTATUM</i> AND <i>SKELETONEMA GREVILLEI</i>, WITH THE DESCRIPTION OF <i>SKELETONEMA ARDENS</i> SP. NOV.<sup>1</sup> (2007)

Skeletonema costatum (Grev.) Cleve emend. Zingone et Sarno and S. grevillei Sarno et Zingone were known only from the type material collected from Hong Kong waters more than a century ago. Both species have now been collected as live material, and their morphology and phylogenetic position are investigated in this study. Eight Skeletonema strains isolated from Florida, USA; Uruguay; and Brazil are attributed to S. costatum , while one strain from Oman is ascribed to S. grevillei based on morphological similarity to the type material of these species. In addition, a new Skeletonema species, S. ardens Sarno et Zingone, is described for a strain from Singapore and two from northern Australian waters. Skeletonema ardens has terminal fultoportula processes ending in a tapered, undulate protrusion and long intercalary fultoportulae with 1:1 junctions. The rimoportula of terminal valves is located at the margin of the valve face. No major morphological variations were observed within S. grevillei and S. ardens along a salinity gradient, whereas in S. costatum , the processes shortened and the valves came into close contact at low salinities, as already described for S. subsalsum (Cleve) Bethge. Consistent with their morphology, Skeletonema costatum and Skeletonema subsalsum also had similar rDNA sequences. Skeletonema grevillei and S. ardens were distinct in the large subunit (LSU) phylogeny. Skeletonema ardens exhibited consistent intraspecific genetic differences in both the LSU and small subunit (SSU) rDNA.
Making hardmetal even harder with dispersed CBN (2007)

Researchers seeking ways to combine the best properties of hardmetals and cubic boron nitride have used a number of advanced techniques including spark plasma sintering, says Ken Brookes…
Experimental stability analysis of geotextile encapsulated-sand systems under wave-loading (2011)

Tese de Doutoramento. Engenharia Civil. Faculdade de Engenharia. Universidade do Porto. 2012
Modulation of lipid profile by fish oil and garlic combination. (1997)

Fish consumption has been shown to influence epidemiology of heart disease, and garlic has been shown to influence triglyceride levels. This study was undertaken to evaluate the effect of fish oil and garlic combinations as a dietary supplement on the lipid subfractions. Forty consecutive subjects with lipid profile abnormalities were enrolled in a single-blind, placebo-controlled crossover study. Each subject received placebo for 1 month and fish oil (1800 mg of eicosapentanoic acid [EPA] + 1200 mg of docosahexanoic acid) with garlic powder (1200 mg) capsules daily for 1 month. Lipid fractionation was performed prior to study initiation, after the placebo period, and after the intervention period. Subjects all had cholesterol levels > 200. Subjects were instructed to maintain their usual diets. Supplementation for 1 month resulted in an 11% decrease in cholesterol, a 34% decrease in triglyceride, and a 10% decrease in low-density lipoprotein (LDL) levels, as well as a 19% decrease in cholesterol/high-density lipoprotein (HDL) risk. Although not significant, there was a trend toward increase in HDL. There was no significant placebo effect. These results suggest that in addition to the known anticoagulant and antioxidant properties of both fish oil and garlic, the combination causes favorable shifts in the lipid subfractions within 1 month. Triglycerides are affected to the largest extent. The cholesterol lowering and improvement in lipid/HDL risk ratios suggests that these combinations may have antiatherosclerotic properties and may protect against the development of coronary artery disease.
Systematische Klärung der Begriffe und ihre Abgrenzung gegen verwandte und benachbarte Begriffe (1963)

Die dichtungstheoretischen Bemühungen der letzten 30 bis 40 Jahre, die einer deutlicheren Fixierung der Grundbegriffe galten, führten zwar noch nicht zu einer eindeutigen Definition der drei Bezeichnungen Stoff, Motiv, Symbol, doch immerhin zu einer umrißhaften Klärung. Stoff, Motiv und Symbol gelten als Komponenten des stofflich-inhaltlichen Strukturelements der Dichtung und stellen drei Stufen der Vergeistigung des vom Dichter angetroffenen oder ihm an Hand gegebenen Materials dar. Der Stoff kann zum Motiv konzentriert, das Motiv zum Symbol überhöht werden.
Privacy enhanced data management for an electronic identity system (2009)

The electronic identity (eID) is being positioned to be a basic tool for identification, authentication and authorization in application domains ranging from eCommerce in private sector to eGovernance in public sector. A practical and flexible eID should be usable in both a network-connected online setting as well as in conventional offline situations. While improving security of communication and enhancing access control to resources, eID schemes also have the potential to become a serious negative factor on user privacy rights. This paper discusses the specific issue of privacy protection in eID systems and considers a range of solutions that could be implemented in a privacy-enhanced eID system featuring both data access and data management.
DNA mismatch repair proficiency executing 5-fluorouracil cytotoxicity in colorectal cancer cells (2011)

5FdU as heteroduplex DNA in plasmid but not linear form triggered cytotoxicity in a MMR-dependent manner. Thus 5FU incorporated into DNA, separated from its effects on RNA, can be recognized by DNA MMR to trigger cell death.
Buccal midazolam for pediatric convulsive seizures: efficacy, safety, and patient acceptability (2013)

Prolonged seizures and status epilepticus are a common acute neurological presentation in pediatric practice. As a result, there is a need for effective and safe medications that can be delivered to convulsing children to effect rapid seizure termination both in hospital and community settings. The challenges of achieving intravenous access, particularly in young children, mandate alternative routes of administration for these drugs. Over the last ten years, midazolam delivered via the buccal mucosa has been demonstrated to be efficacious, safe, and acceptable to children and their caregivers, and a formulation has recently been licensed for use in Europe. The aim of this article is to review the clinical pharmacology with respect to these issues.
Archiving agents for the World Wide Web (2002)

The information available on the World Wide Web changes with incredible speed. New information is added and old information is altered. This means that a document which is important to a user accessing the Web may change, move or even disappear altogether. Described here is an autonomous agent, written in Java, which locally archives documents that are deemed important by the user. These locally archived documents are then available-quickly-when needed.
Mapping tRNA structure in solution using double-strand-specific ribonuclease V<sub>1</sub>from cobra venom (1981)

A method for mapping all base-paired stems in both elongation and initiator tRNAs is described using double-strand-specific ribonuclease V 1 from the venom of the cobra Naja naja oxiana . 32 p-end-labeled RNA is first partially digested with double-strand-specific V 1 nuclease under near physiological conditions, and the resultant fragments are then electrophoretically fractionated by size in adjacent lanes of a polyacrylamide gel run in 90% formamide. After autoradiography, the base-paired nucleotides are definitively located by comparing V 1 generated bands with fragments of known length produced by both Neurospora endonuclease and base-specific ribonucleases. Using the substrates yeast tRNA Phe and E. coli tRNA Met of known three-dimensional structure, we find V 1 nuclease to cleave entirely within every base-paired stem. Our studies also reveal that nuclease V 1 will digest paired nucleotides not hydrogen-bonded by standard Watson-Crick base-pairing. In yeast tRNA Phe cleavage of both wobble base-pairs and nucleotides involved in tertiary base-base hydrogen bonding is demonstrated.
Robust Shape Tracking With Multiple Models in Ultrasound Images (2008)

This paper addresses object tracking in ultrasound images using a robust multiple model tracker. The proposed tracker has the following features: 1) it uses multiple dynamic models to track the evolution of the object boundary, and 2) it models invalid observations (outliers), reducing their influence on the shape estimates. The problem considered in this paper is the tracking of the left ventricle which is known to be a challenging problem. The heart motion presents two phases (diastole and systole) with different dynamics, the multiple models used in this tracker try to solve this difficulty. In addition, ultrasound images are corrupted by strong multiplicative noise which prevents the use of standard deformable models. Robust estimation techniques are used to address this difficulty. The multiple model data association (MMDA) tracker proposed in this paper is based on a bank of nonlinear filters, organized in a tree structure. The algorithm determines which model is active at each instant of time and updates its state by propagating the probability distribution, using robust estimation techniques.
ELASTIN FIBERS IN SCAR TISSUE (1976)

Scar tissue, obtained from humans, was stained for elastin fibers by a new staining method. Elastin fibers were noted at sites where they must have been formed de novo. The morphology and the distribution of elastin in various types of scars are described. Practically no elastin was found in keloids.
The role of ethnography in interactive systems design (1995)

article The role of ethnography in interactive systems design Share on Authors: John Hughes Lancaster Univ., Lancaster, UK Lancaster Univ., Lancaster, UKView Profile , Val King Lancaster Univ., Lancaster, UK Lancaster Univ., Lancaster, UKView Profile , Tom Rodden Lancaster Univ., Lancaster, UK Lancaster Univ., Lancaster, UKView Profile , Hans Andersen Riso National Lab, Roskilde, Denmark Riso National Lab, Roskilde, DenmarkView Profile Authors Info & Claims InteractionsVolume 2Issue 2April 1995 pp 56–65https://doi.org/10.1145/205350.205358Online:01 April 1995Publication History 105citation4,033DownloadsMetricsTotal Citations105Total Downloads4,033Last 12 Months66Last 6 weeks7 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteGet Access
A microfluidic chaotic mixer using ferrofluid (2007)

A novel micromixer which utilizes chaotic mixing induced by ferrofluid actuation is developed. The micromixer is fabricated by a polydimethylsiloxane micromolding technique. The micromixer consists of a T-shaped main mixing channel and two parallel sub-channels that intersect the main channel. Oscillation of a couple of ferrofluid slugs in the sub-channels, induced by external permanent magnet actuation, generates chaotic advection in the main channel flow. To visualize the mixing, red fluorescent particles are supplied to one of the inlets of a T-shaped channel, and mixing flow is observed by a fluorescence microscope and an intensified CCD camera. The mixing experiments are performed with various ferrofluid perturbation frequencies and main stream flow velocities. The optimal mixing conditions determining the upper and lower limits of the most effective Strouhal numbers are found from the experimental results.
Measuring the absolute carrier-envelope phase of many-cycle laser fields (2010)

The carrier-envelope phase (CEP) of high-peak-power, many-cycle laser fields becomes a crucial parameter when such fields are used, in conjunction with polarization gating techniques, in isolated attosecond (asec) pulse generation. However, its measurement has not been achieved so far. We demonstrate a physical process sensitive to the CEP value of such fields and describe a method for its online shot-to-shot monitoring. This work paves the way for the exploitation of energetic isolated asec pulses in studies of nonlinear extreme ultraviolet (XUV) processes and XUV-pump--XUV-probe experiments with asec resolutions.
A Double‐threshold GARCH Model for the French Franc/Deutschmark exchange rate (2001)

This paper combines and generalises a number of recent time series models of daily exchange rate series by using a SETAR model which also allows the variance equation of a GARCH specification for the error terms to be drawn from more than one regime.An application of the model to the French Franc / Deutschmark exchange rate demonstrates that out-of-sample forecasts for the exchange rate volatility are also improved when the restriction that the data it is drawn from a single regime is removed.This result highlights the importance of considering both types of regime shift (i.e.thresholds in variance as well as in mean) when analysing financial time series.