gebhart/patrepeval huggingface dataset:
Milk-induced eczema is associated with the expansion of T cells expressing cutaneous lymphocyte antigen. (1995)

The extravasation of T cells at sites of inflammation is critically dependent on the activity of homing receptors (HR) involved in endothelial cell recognition and binding. Two such HR (the cutaneous lymphocyte antigen [CLA] and L-selectin) have been shown to be selectively involved in T cell migration to skin and peripheral lymph nodes, respectively. This study was designed to assess the relationship between the organ specificity of an allergic reaction to food and the expression of HR on T cells activated in vitro by the relevant food allergen. Peripheral blood mononuclear cells were isolated from seven milk allergic children with a history of eczema when exposed to milk. All patients had a positive prick skin test and double-blind placebo-controlled food challenge to milk. 10 children with either allergic eosinophilic gastroenteritis or milk-induced enterocolitis and 8 nonatopic adults served as controls. Five-parameter flow cytometry using monoclonal antibodies was used for detection of the specific HR on freshly isolated T cells versus T cell blasts induced by a 6-d incubation with casein, as compared with Candida albicans. After in vitro stimulation with casein, but not C. albicans, patients with milk allergy and atopic dermatitis had a significantly greater percentage of CLA+ T cells (P < 0.01) than controls with milk-induced enterocolitis, allergic eosinophilic gastroenteritis, or nonatopic healthy controls. In contrast, the percentage of L-selectin-expressing T cells did not differ significantly between these groups. These data suggest that after casein stimulation allergic patients with milk-induced skin disease have an expanded population of CLA+ T cells, as compared with nonatopics or allergic patients without skin involvement. We postulate that heterogeneity in the regulation of HR expression on antigen-specific T cells may play a role in determining sites of involvement in tissue-directed allergic responses.
Integrated optical add-drop multiplexer using thermally tunable microring resonators (2004)

We present a four channel optical add-drop multiplexer based on vertically coupled microring resonators fabricated in Si3N4/SiO2. The device with a Manhattan-like geometry has a footprint of 0.25 mm2 and can find application in metro-networks. The individual micro-resonators have a 50 μm radius and are thermally tunable over a 4 nm range. The maximum power consumption per ring is 0.5 W. Measurements show that each microring has a bandwidth >10 Gbit and can be thermally tuned in less than 1 ms. The measured on-off resonance in the drop ports of each micro-resonator is 10 dB.
Total solute extraction versus clearance in the evaluation of standard and short hemodialysis. (1989)

The authors compared the efficiency of standard HD (t = 240 minutes, Qb = 300 ml/min, Qd = 500 ml/min) with short HD (t = 150 minutes, Qb = 500 ml/min, Qd = 700 ml/min). The study was carried out in 11 patients in two sequential dialysis sessions, utilizing the same high surface area hollow fiber dialyzers, after a 2 day interdialytic period. With short HD, as expected, the clearance (Cl) of BUN, creatinine (Cr), and phosphates (P) was significantly higher than in standard HD:Cl BUN = 331 vs. 225, Cl Cr = 286 vs. 193, and Cl P = 231 vs. 176 ml/min. No significant difference in the total BUN extraction (measured on the total amount of exhausted dialysate) was found between the two techniques. As to Cr and P, despite higher Cl in short HD, the total extractions were significantly lower. In conclusion, in the evaluation of short HD efficiency, instantaneous Cl can be adequate for small molecules, while for larger solutes, other parameters, such as total extraction, must be considered.
Optimisations logicielles de la localite : le placement precis des donnees en memoire (1998)

Cette etude analyse l'impact des techniques de placement des donnees en memoire sur le taux d'echecs des caches et propose des methodes de placement pour des structures de donnees heterogenes. Dans une premiere partie, une classification des defauts de cache est proposee pour evaluer l'impact du placement des donnees sur le taux d'echecs des caches. Cette classification garde la philosophie du classement propose par m. D. Hill. Cependant, elle permet de montrer l'influence du placement des donnees sur le taux d'echecs. Un placement optimal permettrait d'eliminer les defauts de conflit ainsi qu'une partie des defauts de capacite des programmes. Une heuristique a donc ete developpee pour ameliorer le placement en memoire des scalaires independants. Pour cela, une methode de mesure de la localite des references entre deux donnees a ete mise au point. L'heuristique a ete appliquee sur des traces de programmes. Les resultats obtenus confirment qu'en ameliorant le placement memoire on peut eliminer une grande partie des defauts de capacite et de conflit. Cette heuristique ne peut cependant pas etre utilisee comme telle car il est rare que les programmes manipulent des scalaires sans aucune contraintes de placement. Il faut donc adapter des techniques de placement memoire a chaques types de donnees. Les programmeurs utilisent frequemment des structures de donnees allouees dynamiquement lorsqu'il faut manipuler un grand nombre de donnees. Nous proposons donc d'ameliorer le placement memoire de ce type de donnee en reorganisant les champs des structures et en entrelacant les champs de plusieurs instances en memoire. Pour faciliter l'entrelacement des instances, une librairie d'allocation specifique a ete developpee. La combinaison de ces optimisations permet d'obtenir des gains de performance significatifs en reduisant les taux d'echecs des caches.
Ca(2+)-regulated serine protease associated with the nuclear scaffold. (1992)

The nuclear scaffold (NS) is a proteinaceous network of orthogonally arrayed intermediate filament proteins, termed lamins, which is responsible for nuclear structure. Recent work has demonstrated that a subset of lamins A/C is proteolytically cleaved to produce an ATP-binding protein. This proteolytic cleavage is accomplished by a NS protease activity, which shows a considerable selectivity for lamins A/C and is stringently regulated by Ca2+ in vitro, suggesting that it might also participate in control of NS breakdown in various scenarios. Here, we identify the major NS protease as a novel serine protease with a predominantly chymotryptic-like substrate preference, and we show that even transient perturbations in cytosolic Ca2+ have significant effects on the NS protease activity. This NS protease activity shows extensive similarities to the multicatalytic proteinase complex. In addition to a potential role in control of NS breakdown at mitosis and/or under pathological conditions, this NS protease is also strategically located for other functions, such as inactivation of various oncogenic proteins or maturation-promoting factor.
Comparisons of laboratory and greenhouse indexes of nutrient availability in soils (1966)

Accurate indexes of the availability to plants of nutrients in soils are needed for comparisons of different chemical tests to determine which tests should be used in the laboratory for any given group of soils. This study was conducted to develop and improve techniques for obtaining such standard indexes of nutrient availability to plants. Emphasis was placed on: (a) treating the soil similarly (or uniformly) before testing in the greenhouse and laboratory and (b) avoiding treatments during the greenhouse cropping that might influence the availability of the soil nutrient being tested.\nThe greenhouse technique involved growing plants on undried samples of 24 different soils. Water was added directly to the soils during plant growth, but nutrients other than the one being tested were added by a method which minimized contact with the soil.
Outset of the Morphology of Nanostructured Silica Particles during Nucleation Followed by Ultrasmall-Angle X-ray Scattering (2016)

Nucleation and growth of SBA-15 silica nanostructured particles with well-defined morphologies has been followed with time by small-angle X-ray scattering (SAXS) and ultrasmall-angle X-ray scattering (USAXS), using synchrotron radiation. Three different morphologies have been compared: platelets, toroids, and rods. SEM observations of the particles confirm that two key physical parameters control the morphology: the temperature and the stirring of the solution. USAXS curves demonstrate that primary particles with a defined shape are present very early in the reaction mixture, immediately after a very fast nucleation step. This nucleation step is detected at 10 min (56 °C) or 15 min (50 °C) after the addition of the silica precursor. The main finding is that the USAXS signal is different for each type of morphology, and we demonstrate that the difference is related to the shape of the particles, showing characteristic form factors for the different morphologies (platelet, toroid, and rod). Moreover, the size of the mesocrystal domains is correlated directly with the particle dimensions and shape. When stirred, aggregation between primary particles is detected even after 12 min (56 °C). The platelet morphology is promoted by constant stirring of the solution, through an oriented aggregation step between primary particles. In contrast, toroids and rods are only stabilized under static conditions. However, for toroids, aggregation is detected almost immediately after nucleation.
Spatial behaviour of population density measurements and wall phenomena in a barium vapour laser (1994)

The barium vapour laser, as well as being a high average power source of near to mid-IR radiation, is also a useful test system for studying kinetics of metal vapour lasers. The barium atom and ion ground states have visible upward transitions of sufficient oscillator strength suitable for hook spectroscopy. In contrast, the more popular copper vapour laser requires broadband uv sources and detectors to access the copper ground state, and the copper ion density is impossible to measure by conventional techniques (absorption, emission, and anomalous dispersion spectroscopy). Hook studies of metal vapour lasers have been popular in the last ten years, however, there has been little work on spatially resolved density measurements, particularly of the ground state.
Leitfaden für den Unterricht in der anorganischen Chemie didaktisch bearbeitet. (1910)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTLeitfaden für den Unterricht in der anorganischen Chemie didaktisch bearbeitet.William McPhersonCite this: J. Am. Chem. Soc. 1910, 32, 11, 1534Publication Date (Print):November 1, 1910Publication History Published online1 May 2002Published inissue 1 November 1910https://pubs.acs.org/doi/10.1021/ja01929a019https://doi.org/10.1021/ja01929a019research-articleACS PublicationsRequest reuse permissionsArticle Views16Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Increased Proliferation of Neural Progenitor Cells but Reduced Survival of Newborn Cells in the Contralateral Hippocampus after Focal Cerebral Ischemia in Rats (2002)

Recent studies demonstrated that neurogenesis in the adult hippocampus increased after transient global ischemia; however, the molecular mechanism underlying increased neurogenesis after ischemia remains unclear. The finding that proliferation of progenitor cells occurred at least a week after ischemic insult suggests that the stimulus was not an ischemic insult to progenitor cells. To clarify whether focal ischemia increases the rate of neurogenesis in the remote area, the authors examined the contralateral hemisphere in rats subjected to permanent occlusion of the middle cerebral artery. In the subgranular zone of the hippocampal dentate gyrus, the numbers of bromodeoxyuridine (BrdU)-positive cells increased approximately sixfold 7 days after ischemia. In double immunofluorescence staining, more than 80% of newborn cells expressed Musashi1, a marker of neural stem/progenitor cells, but only approximately 10% of BrdU-positive cells expressed glial fibrillary acidic protein (GFAP), a marker of astrocytes. The number of BrdU-positive cells markedly decreased 28 days after BrdU administration after ischemia, but it was still elevated compared with that of sham-operated rats. In double immunofluorescence staining, 80% of newborn cells expressed NeuN, a marker of differentiated neurons, and 10% of BrdU-positive cells expressed GFAP. However, in the other areas of the contralateral hemisphere including the rostral subventricular zone, the number of BrdU-positive cells remained unchanged. These results showed that focal ischemia stimulated the proliferation of neuronal progenitor cells, but did not support survival of newborn cells in the contralateral hippocampus.
Ultrafast measurement of the optical properties of aluminum during shock-wave breakout (2001)

We have used high-resolution frequency domain interferometry to make ultrafast measurements of shock-induced changes in the optical properties of thin aluminum targets. Measurements with an 800 nm probe wavelength found an unexpected phase shift during a 4.65 GPa shock breakout. Further measurements at 400 nm associate this phase shift with the pressure dependence of the 1.5 eV interband transition in aluminum. Data taken at several angles of incidence allowed the separation of optical from material motion effects, yielding an effective complex index for the shocked material.
Role Of Macrophages On The Benefits Of O??G On Susceptibility To Infection Following Exercise Stress (2005)

Exhaustive exercise has been associated with increased risk for respiratory infection. Oat β-glucan (OβG), a soluble fiber with mild immunostimulant activity, can offset the decrease in macrophage (MΦ) antiviral resistance and increased risk of infection associated with exercise stress. PURPOSE To determine the role of lung MΦs on the benefits of OβG on susceptibility to infection following exercise stress. METHODS Exercise mice were run to fatigue on a treadmill for 3 consecutive days prior to infection. OβG was fed in the drinking water for 10 consecutive days prior to infection. Mice were administered 100μl of clodronate (Ex-H2O-CL2MDP, Ex-OβG-CL2MDP, Con-H2O-CL2MDP and Con-OβG-CL2MDP) or phosphate buffered saline (Ex-H2OPBS, Ex-OβG-PBS, Con-H2O-PBS and Con-OβG-PBS) encapsulated in liposomes, via an intra-nasal route on the 1st day of exercise and the 4th day following infection. MΦs ingest the liposomes and are killed by the clodronate through apoptosis. This procedure has previously been found to deplete approximately 75% of lung MΦs. Fifteen minutes following exercise or rest on the last day of training, mice were intranasally inoculated with HSV-1 (1.28 × 105 PFUs). They were monitored twice daily for morbidity, mortality and symptom severity for 21 days. RESULTS As we have previously shown, exercise increased morbidity, mortality and symptom severity versus control, and this increase was attenuated in OβG fed animals. MΦ depletion negated the beneficial effects of OβG. CONCLUSION These data suggest that MΦs play an important role in the mechanism whereby OβG exerts its beneficial effects on reducing susceptibility to infection following exhaustive exercise. Funded by the American College of Sports Medicine.
Early intervention at the stage of molecular relapse afterallogeneic haematopoietic stem cell transplantation (2009)

Early intervention at the stage of molecular relapse after
allogeneic haematopoietic stem cell transplantation
Power allocation analysis for dynamic power utility in cognitive radio systems (2015)

The focus of this paper is to investigate the fundamental limits of power allocation when taking into account a dynamic power pricing scheme. This paper proposes an optimal power allocation analysis for wireless systems when real time power pricing is available. We propose to minimize the total power consumption cost while ensuring minimum individual and total throughput limits. We consider different models for the power pricing function. Analytic solutions for the power allocation are derived for each model. The derived solutions are shown to be modified versions of the water-filling solution. Low-complexity algorithms are proposed for the resource allocation with each pricing model. Performance comparison and pricing effect are shown through simulations.
Enforcing the tolerance to noise of a quantum key distribution protocol with continuous variables (2007)

info:eu-repo/semantics/published
Evidence-based Approach to Interacting with Open Student Models (2007)

Research efforts focused on developing active are currently underway. Active reports are designed to foster communication among teachers, students, and parents by listening to all stakeholders, using assessment information to guide teaching and learning, and to reconcile potential conflicts. Open student models can handle different views of the student. These views support different kinds of assessment information coming from a variety of sources (e.g. results from summative and formative assessments). As teachers, students, and parents interact with open student models, assessment claims (e.g. students' self-assessment, systems' and teachers' assessment of student knowledge) may evolve from unsupported claims to evidence-based arguments. Paths on this evidentiary argument space are characterized by rich interactions among sources of evidence that may challenge personal claims and improve metacognitive skills. This paper (a) presents an evidence-based approach to interacting with open student models that builds on existing research on open student models, evidentiary arguments and evidence-centered design, (b) illustrates this approach in the context of an assessment-based learning environment called Math Intervention Module (MIM), and (c) reports on a study carried out with Algebra teachers/assessment specialists aimed at evaluating the feasibility of implementing this approach in real settings.
Equilibrium of Urea Synthesis. I. (1972)

Abstract A test of the equilibrium conversion of CO2 to urea was carried out using a batch autoclave. Some results different from those reported by Frèjacques were obtained, as was expected from the latest data on commercial urea plants. The equilibrium conversion reached its maximum value at about 195°C by 5–15% higher than that reported by Frèjacques. On the contrary, at temperatures above 200°C the value was lower, and falled rapidly with the raise of temperature. This phenomenon may be due to the mechanism of the equilibrium of urea synthesis, and not to the experimental method, as our sampling was made directly from the liquid phase. The equilibrium conversion, x, may be expressed with respect to NH3/CO2, a, H2O/CO2, b, and temperature, t, as (Remark: Graphics omitted.) Therefore, a limited conversion exists in the conventional urea process.
Interpretation of Ellipsometry Measurements Taken from Annealed Heavily Arsenic‐Implanted Silicon (1993)

Ellipsometry measurements taken from annealed arsenic‐implanted silicon substrates, and from the native oxides forming on these surfaces, are interpreted with the use of the ancillary techniques Auger electron spectroscopy (AES) and transmission electron microscopy (TEM). It is demonstrated that erroneous over estimates of initial and time‐evolved native oxide thicknesses are made by ellipsometry when common assumptions for bare undoped silicon surfaces are used. It is further shown that discrepancies between common interpretations of ellipsometric data and AES‐TEM can be reconciled by invoking a shift in substrate refractive index and extinction coefficient with increasing dopant dose.
Regional climate hindcast simulations within EURO-CORDEX: evaluation of a WRF multi-physics ensemble (2015)

Abstract. In the current work we present six hindcast WRF (Weather Research and Forecasting model) simulations for the EURO-CORDEX (European Coordinated Regional Climate Downscaling Experiment) domain with different configurations in microphysics, convection and radiation for the time period 1990–2008. All regional model simulations are forced by the ERA-Interim reanalysis and have the same spatial resolution (0.44°). These simulations are evaluated for surface temperature, precipitation, short- and longwave downward radiation at the surface and total cloud cover. The analysis of the WRF ensemble indicates systematic temperature and precipitation biases, which are linked to different physical mechanisms in the summer and winter seasons. Overestimation of total cloud cover and underestimation of downward shortwave radiation at the surface, mostly linked to the Grell–Devenyi convection and CAM (Community Atmosphere Model) radiation schemes, intensifies the negative bias in summer temperatures over northern Europe (max −2.5 °C). Conversely, a strong positive bias in downward shortwave radiation in summer over central (40–60%) and southern Europe mitigates the systematic cold bias over these regions, signifying a typical case of error compensation. Maximum winter cold biases are over northeastern Europe (−2.8 °C); this location suggests that land–atmosphere rather than cloud–radiation interactions are to blame. Precipitation is overestimated in summer by all model configurations, especially the higher quantiles which are associated with summertime deep cumulus convection. The largest precipitation biases are produced by the Kain–Fritsch convection scheme over the Mediterranean. Precipitation biases in winter are lower than those for summer in all model configurations (15–30%). The results of this study indicate the importance of evaluating not only the basic climatic parameters of interest for climate change applications (temperature and precipitation), but also other components of the energy and water cycle, in order to identify the sources of systematic biases, possible compensatory or masking mechanisms and suggest pathways for model improvement.
MUGENE : Approche combinée de génétique, de génomique et de biologie musculaire pour prédire la qualité de la viande bovine (2008)

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