gebhart/patrepeval huggingface dataset:
A Duration Analysis of Foreclosures to Sheriff Sales in Light of the Financial Crisis (2015)

The purpose of this paper is to address the efficiency of turning over homes that have gone into foreclosure. For the town of Muskego, Wisconsin, the number of homes going to foreclosure has decreased from the pinnacle of the housing crisis. Furthermore, the likelihood of a house going to sheriff sale after being foreclosed upon has gradually decreased from this point in time as well. This paper employs a probit model to determine the likelihood that a foreclosed home will go to sheriff sale compared to the reference years (2001-2004). From the initial stages of the housing crisis, homes in foreclosure were more likely to go to sheriff sale compared to the reference years, but this effect diminishes over time. Furthermore, a hazard model is implemented which confirms the results of the probit from a duration perspective.
Strategy for surveying the proteome using affinity proteomics and mass spectrometry (2009)

Antibody-based microarrays is a rapidly evolving technology that has gone from the first proof-of-concept studies to more demanding proteome profiling applications, during the last years. Miniaturized microarrays can be printed with large number of antibodies harbouring predetermined specificities, capable of targeting high- as well as low-abundant analytes in complex, nonfractionated proteomes. Consequently, the resolution of such proteome profiling efforts correlate directly to the number of antibodies included, which today is a key limiting factor. To overcome this bottleneck and to be able to perform in-depth global proteome surveys, we propose to interface affinity proteomics with MS-based read-out, as outlined in this technical perspective. Briefly, we have defined a range of peptide motifs, each motif being present in 5-100 different proteins. In this manner, 100 antibodies, binding 100 different motifs commonly distributed among different proteins, would potentially target a protein cluster of 10(4) individual molecules, i.e. around 50% of the nonredundant human proteome. Notably, these motif-specific antibodies would be directly applicable to any proteome in a specie independent manner and not biased towards abundant proteins or certain protein classes. The biological sample is digested, exposed to these immobilized antibodies, whereby motif-containing peptides are specifically captured, enriched and subsequently detected and identified using MS.
Reactions of coordinated ligands. XVII. Reactions between tris(ethylenediamine)nickel(II) ion and .alpha.-hydroxy ketones (1967)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTReactions of coordinated ligands. XVII. Reactions between tris(ethylenediamine)nickel(II) ion and .alpha.-hydroxy ketonesThomas E. MacDermott, Barbara E. Sewall, and Daryle H. BuschCite this: J. Am. Chem. Soc. 1967, 89, 23, 5784–5787Publication Date (Print):November 1, 1967Publication History Published online1 May 2002Published inissue 1 November 1967https://pubs.acs.org/doi/10.1021/ja00999a009https://doi.org/10.1021/ja00999a009research-articleACS PublicationsRequest reuse permissionsArticle Views301Altmetric-Citations4LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Shoot Regeneration in Root and Callus Cultures of Hypericum perforatum. (1992)

[in Japanese]
Isoform-Selective ATAD2 Chemical Probe with Novel Chemical Structure and Unusual Mode of Action (2017)

ATAD2 (ANCCA) is an epigenetic regulator and transcriptional cofactor, whose overexpression has been linked to the progress of various cancer types. Here, we report a DNA-encoded library screen leading to the discovery of BAY-850, a potent and isoform selective inhibitor that specifically induces ATAD2 bromodomain dimerization and prevents interactions with acetylated histones in vitro, as well as with chromatin in cells. These features qualify BAY-850 as a chemical probe to explore ATAD2 biology.
Complete Genome Sequence of Treponema paraluiscuniculi, Strain Cuniculi A: The Loss of Infectivity to Humans Is Associated with Genome Decay (2011)

Treponema paraluiscuniculi is the causative agent of rabbit venereal spirochetosis. It is not infectious to humans, although its genome structure is very closely related to other pathogenic Treponema species including Treponema pallidum subspecies pallidum, the etiological agent of syphilis. In this study, the genome sequence of Treponema paraluiscuniculi, strain Cuniculi A, was determined by a combination of several high-throughput sequencing strategies. Whereas the overall size (1,133,390 bp), arrangement, and gene content of the Cuniculi A genome closely resembled those of the T. pallidum genome, the T. paraluiscuniculi genome contained a markedly higher number of pseudogenes and gene fragments (51). In addition to pseudogenes, 33 divergent genes were also found in the T. paraluiscuniculi genome. A set of 32 (out of 84) affected genes encoded proteins of known or predicted function in the Nichols genome. These proteins included virulence factors, gene regulators and components of DNA repair and recombination. The majority (52 or 61.9%) of the Cuniculi A pseudogenes and divergent genes were of unknown function. Our results indicate that T. paraluiscuniculi has evolved from a T. pallidum-like ancestor and adapted to a specialized host-associated niche (rabbits) during loss of infectivity to humans. The genes that are inactivated or altered in T. paraluiscuniculi are candidates for virulence factors important in the infectivity and pathogenesis of T. pallidum subspecies.
A single barrier varactor quintupler at 170 GHz (1995)

InGaAs-InAlAs single-barrier varactor (SBV) diodes are tested as frequency quintuplers. The diodes were tested in a crossed-waveguide structure and provided output frequencies between 148 and 187 GHz. The highest observed flange-to-flange efficiency was 0.78% at an output frequency of 172 GHz. This is nearly four times greater than the best quintupler efficiency obtained for previous SBV varactors made from the GaAs-AlGaAs materials system.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
A composite microdose Adaptive Response (AR) and Bystander Effect (BE) model–application to low LET and high LET AR and BE data (2008)

The results of the model analysis is consistent with a premise that both Bystander damage and Adaptive Response radioprotection can occur in the same cell type, derived from the same cell species. The model provides an analytical tool to biophysically study the combined effects of BE and AR.
Edge-labeling using dictionary-based relaxation (1990)

An improved application of probabilistic relaxation to edge labeling is presented. The improvement derives from the use of a representation of the edge process that is internally consistent and which utilizes a more complex description of edge structure. The application uses a dictionary to represent permitted labelings of the entire context-conveying neighborhood of each pixel. Details are given of the dictionary approach and the related representation of the edge process. A comparison with other edge-postprocessing strategies is provided.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Etanercept, a soluble tumor necrosis factor receptor, palliates constitutional symptoms in patients with myelofibrosis with myeloid metaplasia: results of a pilot study (2002)

Patients with myelofibrosis with myeloid metaplasia (MMM) often experience debilitating constitutional symptoms such as drenching night sweats, profound fatigue, unexplained fevers, and unintentional weight loss. Tumor necrosis factor (TNF) contributes to organ fibrosis and hypercatabolic symptoms in a variety of disease states. We conducted an open-label pilot study of etanercept, a soluble TNF receptor, administered at a dose of 25 mg subcutaneously twice weekly for up to 24 weeks in 22 patients with MMM. Of 20 evaluable patients, 12 (60%) experienced an improvement in constitutional symptoms, and 4 (20%) had an objective response (improvement in peripheral cytopenias or spleen size). The degree of marrow fibrosis was unchanged, and only minor changes in overall marrow cellularity were observed. Toxicity was mild, with injection site reactions (20%) and minor infections (10%) as the most common side effects. One patient developed reversible pancytopenia. Etanercept may be useful for palliation of constitutional symptoms in MMM.
The Editor's Page (2001)

ADVERTISEMENT RETURN TO ISSUEEditorialNEXTThe Editor's PageDietmar SeyferthView Author Information EditorCite this: Organometallics 2001, 20, 8, 1487Publication Date (Web):April 9, 2001Publication History Published online9 April 2001Published inissue 1 April 2001https://pubs.acs.org/doi/10.1021/om010195zhttps://doi.org/10.1021/om010195zeditorialACS PublicationsCopyright © 2001 American Chemical Society. This publication is available under these Terms of Use. Request reuse permissions This publication is free to access through this site. Learn MoreArticle Views279Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail PDF (36 KB) Get e-AlertscloseSUBJECTS:Anions,Ligands,Liquids,Molecules,Organometallic compounds Get e-Alerts
Effect of sorghum flour composition and particle size on quality properties of gluten-free bread (2014)

White, food-grade sorghum was milled to flour of varying extraction rates (60%, 80%, and 100%) and pin-milled at different speeds (no pin-milling, low-speed, and high-speed) to create flours of both variable composition and particle size. Flours were characterized for flour composition, total starch content, particle size distribution, color, damaged starch, and water absorption. Bread was characterized for specific volume, crumb structure properties, and crumb firmness. Significant differences were found (P < 0.05) in the composition of sorghum flours of varying extraction rate, most notably for fiber and total starch contents. Flour particle size and starch damage were significantly impacted by extraction rate and speed of pin-milling. Water absorption increased significantly with increasing extraction rate and pin-milling speed. Breads produced from 60% extraction flour had significantly higher specific volumes, better crumb properties, and lower crumb firmness when compared with all other extractions and flour types. The specific volume of bread slices ranged from 2.01 mL/g (100% extraction, no pin-milling) to 2.54 mL/g (60% extraction, low-speed pin-milling), whereas the firmness ranged from 553.28 g (60% extraction, high-speed pin-milling) to 1096.26 g (commercial flour, no pin-milling). The bread characteristics were significantly impacted by flour properties, specifically particle size, starch damage, and fiber content (P < 0.05).
ChemInform Abstract: SOME REACTIONS OF POLYFLUOROALKYL ETHERS AND THE PREPARATION OF BIS(TRIFLUORVINYL) ETHER (1975)

Abstract Der dl‐ bzw. meso‐Bis(trifluoräthyl)äther (I) ergibt mit AlCl 3 und BCl 3 die chlorierten Produkte (II) und (III).
Reintroduction of H5N1 highly pathogenic avian influenza virus by migratory water birds, causing poultry outbreaks in the 2010–2011 winter season in Japan (2011)

H5N1 highly pathogenic avian influenza virus (HPAIV) was reintroduced and caused outbreaks in chickens in the 2010-2011 winter season in Japan, which had been free from highly pathogenic avian influenza (HPAI) since 2007 when HPAI outbreaks occurred and were controlled. On 14 October 2010 at Lake Ohnuma, Wakkanai, the northernmost part of Hokkaido, Japan, H5N1 HPAIVs were isolated from faecal samples of ducks flying from their nesting lakes in Siberia. Since then, in Japan, H5N1 HPAIVs have been isolated from 63 wild birds in 17 prefectures and caused HPAI outbreaks in 24 chicken farms in nine prefectures by the end of March in 2011. Each of these isolates was genetically closely related to the HPAIV isolates at Lake Ohnuma, and those in China, Mongolia, Russia and Korea, belonging to genetic clade 2.3.2.1. In addition, these isolates were genetically classified into three groups, suggesting that the viruses were transmitted by migratory water birds through at least three different routes from their northern territory to Japan. These isolates were antigenic variants, which is consistent with selection in poultry under the immunological pressure induced by vaccination. To prevent the perpetuation of viruses in the lakes where water birds nest in summer in Siberia, prompt eradication of HPAIVs in poultry is urgently needed in Asian countries where HPAI has not been controlled.
Recognising and Avoiding Water-Production Intervals Using Integrated Petrophysical Methods: A Case Study from the Piceance Basin, USA (2013)

Abstract A regionally extensive tight-gas accumulation in the Cretaeous age Mesa Verde Group of the Piceance Basin, Colorado, USA has been actively developed for over a decade. Daily production has increased from under 200 MMCFD in the year 2000 to over 1 BCFD currently. However, in some parts of the basin, the commercial development of the asset is challenged by water production. The tight gas reserves occur in a stacked, multi-sand system. It includes over 100 stacked reservoir targets distributed over approximately 5,000ft of formation vertically. Water can be produced from any of these targets geographically. Produced water can cause serious wellbore hydraulic issues and also increase water disposal cost. Therefore, recognizing and avoiding high water production zones before hydraulically fracturing is critical. A workflow for evaluating water-production risk has been developed. The workflow includes 1) deriving reservoir properties (porosity, water saturation, etc.) from open-hole and/or cased-hole logs, 2) calibrating the log measurements with a robust core-based, grain-size-dependent permeability prediction model, and 3) using water saturation in conjunction with permeability to evaluate the likelihood of low capillary or imbibed water for individual sands. This gives a qualitative analysis of water risk on a cross-plot of permeability versus permeability-water-saturation separation (k-Sw screening) with no water production risk (bound water) to high water production risk. The k-Sw screening concept has been verified with logs and production data from over 50 wells in the northern part of the basin. The workflow helped decrease water production thereby improving the economics of the tight gas play.
Impact of physical activity and performance on medical care costs among the Japanese elderly (2010)

This prospective study indicates that a higher level of PA is associated with lower medical care costs among the Japanese elderly irrespective of physical performance.
Inhibition of Src Kinases Combined with CD40 Ligand Blockade Prolongs Murine Cardiac Allograft Survival (2005)

The myeloid and B cell Src family kinases, Hck and Lyn, rather than the T cell Src kinase Lck, show the greatest increase in expression and total activity in rejecting allografts. Both rejected and long-surviving grafts show significant increases in SFK expression and acitivity.
Characterizing e-business workloads using fractal methods (2002)

Understanding the workload of Web and e-business sites is a fundamental step in sizing the IT infrastucture that supports these sites and in planning for their evolution so that Quality of Service (QoS) golas are met within cost constraints. This paper presents two approaches for characterzing e-business sessions: distace-based and fractal (session similarity). We apply both approaches to an actual e-business workload to understand what customers do, what navigational patterns they follow, and to identify groups of users that have similar behaviour. We also present the benefits and drawbacks of both approaches. The main contribution of this work is presentation of techniques that improve the process of workload characterization.
The Application of Multispectral Techniques to Analytical Electron Microscopy (1992)

The York multispectral analytical electron microscope (MULSAM) was the first instrument specifically designed to acquire and process multiple Auger, X-ray, backscattered electron, elastically scattered electron, scanning electron microscopy (SEM) and specimen absorption current images simultaneously. Analyzing combinations of these signals with multispectral correlation techniques yields more information than would normally be obtained by treating each image separately. This paper reports some of the multispectral methods we have investigated at York which may be of use to other workers. Included are (1) a method that corrects for beam current fluctuations during long acquisition runs which is based on the anti-correlation between SEM and specimen current images, (2) the classification of topography for crystalline specimens by correlation partitioning of backscattered electron images and (3) the enhancement of surface state contrast in multi spectral scanning tunneling microscopy (STM) images using the Hotelling transform. The last example is intended to demonstrate that these techniques can also be applied to other fields in microscopy.
The Measurement of Adiabatic Differential Magnetic Susceptibility Near 1° Absolute. The Heat Capacity of Gadolinium Phosphomolybdate Tridecahydrate from 0.17 to 4.7° Absolute (1941)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe Measurement of Adiabatic Differential Magnetic Susceptibility Near 1° Absolute. The Heat Capacity of Gadolinium Phosphomolybdate Tridecahydrate from 0.17 to 4.7° AbsoluteW. F. Giauque, J. W. Stout, C. J. Egan, and C. W. ClarkCite this: J. Am. Chem. Soc. 1941, 63, 2, 405–410Publication Date (Print):February 1, 1941Publication History Published online1 May 2002Published inissue 1 February 1941https://pubs.acs.org/doi/10.1021/ja01847a017https://doi.org/10.1021/ja01847a017research-articleACS PublicationsRequest reuse permissionsArticle Views49Altmetric-Citations9LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
<scp><i>GGPS1</i></scp>‐associated muscular dystrophy with and without hearing loss (2022)

Ultra-rare biallelic pathogenic variants in geranylgeranyl diphosphate synthase 1 (GGPS1) have recently been associated with muscular dystrophy/hearing loss/ovarian insufficiency syndrome. Here, we describe 11 affected individuals from four unpublished families with ultra-rare missense variants in GGPS1 and provide follow-up details from a previously reported family. Our cohort replicated most of the previously described clinical features of GGPS1 deficiency; however, hearing loss was present in only 46% of the individuals. This report consolidates the disease-causing role of biallelic variants in GGPS1 and demonstrates that hearing loss and ovarian insufficiency might be a variable feature of the GGPS1-associated muscular dystrophy.
Time Delay Estimation via Multichannel Cross-Correlation (2006)

Time delay estimation (TDE) in a reverberant acoustical environment is a very challenging and difficult problem. This paper tackles the problem by exploiting the redundant information provided by multiple microphone sensors. To do so, the multichannel crosscorrelation coefficient (MCCC) is re-derived, in a new way, to connect it to the well-known linear interpolation technique. Some interesting properties and bounds of MCCC are discussed, and a recursive algorithm is then introduced so that MCCC can be estimated and updated efficiently when new data snapshots are available. We then apply the MCCC to the TDE problem, resulting a multichannel cross-correlation algorithm that can be treated as a natural generalization of the generalized cross-correlation (GCC) TDE method to the multichannel case. It is shown that this method can take advantage of the redundancy provided by multiple microphone sensors to improve TDE against both reverberation and noise.
[Technical aspects of the surgery of atherosclerotic carotid stenoses]. (1993)

The aim of the present paper is to present a brief critical analysis of the technical aspects of surgery for atherosclerotic carotid stenoses, including reconstructive techniques, preoperative evaluation of neurologic risk and intraoperative monitoring and cerebral protection. Our present personal protocol is presented.