gebhart/patrepeval huggingface dataset:
Treatment-resistant depression. (2009)

Up to two thirds of patients with major unipolar depression will not respond to the first medication prescribed. Depression may be considered resistant to treatment when at least two trials with antidepressants from different pharmacologic classes (adequate in dose, duration, and compliance) fail to produce a significant clinical improvement. Evidence regarding the effectiveness of psychotherapy for treatment-resistant depression is limited. A recent high-quality trial found that patients who did not respond to citalopram and who received cognitive behavior therapy (with or without continued citalopram) had similar response and remission rates to those who received other medication regimens. Initial remission rates in that trial were 37 percent, and even after three additional trials of different drugs or cognitive behavior therapy, the cumulative remission rate was only 67 percent. In general, patients who require more treatment steps have higher relapse rates, and fewer than one half of patients achieve sustained remission. No treatment strategy appears to be better than another. Electroconvulsive therapy is effective as short-term therapy of treatment-resistant depression. There is no good-quality evidence that vagal nerve stimulation is an effective treatment for this condition.
Antiosteoporotic Effects of <i>Lactobacillus</i>-Fermented Soy Skim Milk on Bone Mineral Density and the Microstructure of Femoral Bone in Ovariectomized Mice (2011)

Osteoporosis is a major skeletal disease associated with loss of estrogen in postmenopausal women. In this study, Lactobacillus paracasei subsp. paracasei NTU 101 (NTU 101F) and Lactobacillus plantarum NTU 102 (NTU 102F) were used as starters to ferment soy skim milk. This was then used as a nutritional supplement for 8 weeks to ovariectomized (OVX) mice. This study reveals that soy skim milk fermented with lactobacilli can increase the contents of aglycone isoflavones, soluble calcium, and vitamin D(3). The trabecular bone volumes and trabecular number of the distal femur in mice fed NTU 101F increased by a factor of 1.48 and 1.74 compared with the OVX group. The bone network density and thickness of the distal metaphyseal trabecular in mice fed NTU 101F and Fosamax was significantly greater than that of OVX mice. These results suggest that fermented soy skim milk can attenuate bone loss in OVX mice and lower the risk of osteoporosis.
RimM and RbfA Are Essential for Efficient Processing of 16S rRNA in <i>Escherichia coli</i> (1998)

The trmD operon is located at 56.7 min on the genetic map of the Escherichia coli chromosome and contains the genes for ribosomal protein (r-protein) S16, a 21-kDa protein (RimM, formerly called 21K), the tRNA (m1G37)methyltransferase (TrmD), and r-protein L19, in that order. Previously, we have shown that strains from which the rimM gene has been deleted have a sevenfold-reduced growth rate and a reduced translational efficiency. The slow growth and translational deficiency were found to be partly suppressed by mutations in rpsM, which encodes r-protein S13. Further, the RimM protein was shown to have affinity for free ribosomal 30S subunits but not for 30S subunits in the 70S ribosomes. Here we have isolated several new suppressor mutations, most of which seem to be located close to or within the nusA operon at 68.9 min on the chromosome. For at least one of these mutations, increased expression of the ribosome binding factor RbfA is responsible for the suppression of the slow growth and translational deficiency of a deltarimM mutant. Further, the RimM and RbfA proteins were found to be essential for efficient processing of 16S rRNA.
The Clinical Laboratory: Testing the Complement System (1998)

Our current knowledge of the participation of complement in human disease and its biological importance in host defense is closely connected to progress in laboratory complement diagnosis. Although it is well documented that complement plays a decissive role in the pathogenesis of various diseases, it is somewhat surprising that achievements in complement research only find limited implementation in the clinic. Despite the presence of a broad spectrum of commercially available reagents, a comprehensive analysis of complement is still performed in only a few specialized laboratories. In most clinics, complement diagnosis is confined — as it was 20 years ago — to immunochemical determinations of C3 and C4, sometimes of factor B and C1 inhibitor (C1-INH), and is only occasionally extended to hemolytic titration of total functional activity (CH50). Rare, but clinically important complement deficiency states are thus frequently overlooked. The limited acceptance of complement assays as an essential part of laboratory diagnosis in various diseases may be explained by minor therapeutic consequences, due to the lack of reagents for specific pharmacologic intervention. Recent advances in the field of complement-directed therapy is expected to influence positively clinicians' opinion on the necessity for complement diagnosis. The management of patients with autoimmune diseases or adverse reactions to drugs and artificial surfaces or those at risk from trauma-related syndromes such as adult respiratory distress syndrome (ARDS) and multiple organ failure, benefits from early diagnosis. There is still a substantial need for laboratory parameters as early markers of deleterious clinical conditions. Longitudinal studies of patients are of advantage. The clinician can observe changes in the complement profile which may be indicative of activation resulting from disease activity or clinical intervention. The utility of complement diagnosis for monitoring of disease activity has been extensively demonstrated in cases of systemic lupus erythematosus (SLE) [12, 36, 86, 106], and elevated plasma levels of complement activation products have been shown to be of prognostic value in recognizing patients with impending transplant rejection [87] and trauma-induced adult respiratory distress syndrome and multiple organ failure [51, 178, 188]. A complete complement profile provides valuable information in diagnosing the various forms of hypocomplementemic glomerulonephritis and may substantially aid in the interpretation of findings in renal biopsies [60, 181].KeywordsSystemic Lupus ErythematosusComplement ActivationParoxysmal Nocturnal HemoglobinuriaAdult Respiratory Distress SyndromeHereditary AngioedemaThese keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
Classified transform coding of images using vector quantization (2003)

An adaptive image coding scheme, called classified transform vector quantization, is proposed. It efficiently exploits correlation in large image blocks by taking advantage of transform coding (TC) and vector quantization (VQ), while overcoming the suboptimalities of TC and avoiding the complexity obstacle of VQ. After local mean luminance values are removed in the spatial domain using two-stage interpolative VQ, the residual errors are encoded in the transform domain by means of perceptual block classification and adaptive subvector construction. This scheme avoids the use of scalar quantization of DC coefficients in the transform domain and yet substantially reduces the blocking effect that tends to arise at low bit rates. Good reconstructed images have been obtained at rates between 0.3 and 0.4 bits/pixel, depending on the nature of the test images. The technique also permits progressive image transmission and reproduces errorless images with compression of about 5.0 bits/pixel. Experimental results indicate that an efficient bit allocation in the coding process produces a substantial improvement in performance.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Review: <i>BODIE'S GOLD: Tall Tales & True History from a California Mining Town</i>, by Marguerite Sprague and <i>BODIE'S BOSS LAWMAN: The Frontier Odyssey of Constable John W. Kirgan</i>, by Bill Merrill and David Carle (2004)

Book Review| April 01 2004 Review: BODIE'S GOLD: Tall Tales & True History from a California Mining Town, by Marguerite Sprague and BODIE'S BOSS LAWMAN: The Frontier Odyssey of Constable John W. Kirgan, by Bill Merrill and David Carle BODIE'S GOLD: Tall Tales & True History from a California Mining TownMarguerite SpragueBODIE'S BOSS LAWMAN: The Frontier Odyssey of Constable John W. KirganBill MerrillDavid Carle Michael S. Green Michael S. Green Search for other works by this author on: This Site PubMed Google Scholar Southern California Quarterly (2004) 86 (1): 88–89. https://doi.org/10.2307/41172202 Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter LinkedIn Tools Icon Tools Cite Icon Cite Search Site Citation Michael S. Green; Review: BODIE'S GOLD: Tall Tales & True History from a California Mining Town, by Marguerite Sprague and BODIE'S BOSS LAWMAN: The Frontier Odyssey of Constable John W. Kirgan, by Bill Merrill and David Carle. Southern California Quarterly 1 April 2004; 86 (1): 88–89. doi: https://doi.org/10.2307/41172202 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentSouthern California Quarterly Search This content is only available via PDF. Copyright 2004 Historical Society of Southern California Article PDF first page preview Close Modal You do not currently have access to this content.
Comparison of the Reactivity of Platinum(II) and Platinum(0) Complexes with Iminophosphine and Phosphinocarbonyl Ligands (2011)

Iminophosphines 2-(PPh2)C6H4C(R)═NR′ (L) (R = H, Me; R′ = 2,6-Me2C6H3 or 2,6-Pri2C6H3) react with Pt(II) precursors to form chelated P,N complexes [PtLX2] (X = Me, Et, Cl), whereas with [Pt(C7H10)3] (C7H10 = norbornene) and other labile Pt(0) precursors coordination is via phosphorus and chelation is not observed. However, activation of the imine H or the methyl C–H bond of the ketoimine affords P,C metallacyclic hydride complexes [PtH(PPh2C6H4C═NR′)L] and [PtH(PPh2C6H4C(═NR′)CH2)L], respectively. Under more forcing conditions the ketoimine complex undergoes a second metalation reaction, forming cis- and trans-bis-P,C-metallacyclic complexes. By contrast, reaction of the phosphinocarbonyl ligands 2-(PPh2)C6H4C(R)═O (L′) (R = H, Me) with Pt(II) precursors always affords bis-monodentate complexes [PtL′2X2] initially. Where X = Me, methane elimination occurs, forming five- (R = H) or six- (R = Me) membered P,C metallacyclic complexes, [PtMe(PPh2C6H4CO)L′]. On heating, the second phosphinocarbonyl metalates, forming cis- and trans-bis-P,C-metallacyclic complexes. X-ray crystallography of the cis-metalla-β-diketone complex [Pt(PPh2C6H4CO)2] established the closeness of the carbonyl oxygen atoms, which readily capture H+ and other cations, forming stable complexes. These bis-chelate complexes also form readily from the reaction of the phosphinocarbonyls with [Pt(C7H10)3] via an intermediate norbornyl complex (R = H) or a 5,6-ring bis-chelate (R = Me) in which a hydride is transferred from one ketone to partially reduce the second ketone.
The analysis of multivariate longitudinal data: A review (2012)

Longitudinal experiments often involve multiple outcomes measured repeatedly within a set of study participants. While many questions can be answered by modeling the various outcomes separately, some questions can only be answered in a joint analysis of all of them. In this article, we will present a review of the many approaches proposed in the statistical literature. Four main model families will be presented, discussed and compared. Focus will be on presenting advantages and disadvantages of the different models rather than on the mathematical or computational details.
Advancing the capacity of phosphorescent white LED based visible light communication network (2015)

We propose to utilize pre-equalization circuit and receiver diversity technology to advancing the capacity of phosphorescent white LED based VLC system. An indoor and an outdoor VLC system have been experimentally demonstrated.
ChemInform Abstract: REACTION OF TRIFLUOROMETHYL HYPOFLUORITE WITH N‐SUBSTITUTED AZIRIDINES (1980)

Abstract Trifluormethylhypofluorid (II) lagert sich unter Ringöffnung an Aziridine (I) an.
Characterization of Reversed-Phase Liquid Chromatographic Stationary Phases Using Solvatochromism and Multivariate Curve Resolution (1999)

The solvatochromic method has been used to probe the solid/solution interface of bare silica and two modified silica surfacesphenyl bonded and C18 bondedin mobile-phase mixtures of methanol−water and acetonitrile−water. Spectral measurements of solvatochromic dye solutions in different mobile-phase compositions and of slurries wetted by these same solutions have been recorded and used to characterize the different solid/solution interfaces. Multivariate curve resolution has been employed to resolve the spectra collected into the contributions due to the different solvated species of the dye, i.e., those related to the dye associated with the stationary phase and those related to the dye solvated by the different species present in the mobile phase. Spectral profiles of the dyes solvated by a methanol−water complex in the presence of stationary phase have been resolved for the first time. Chromatographic capacity factors (k‘) have been measured, and they have complementary information about how the retention of the dye changes with the mobile-phase composition on the different silica surfaces. The validity of the spectral studies performed to characterize real chromatographic environments, which are usually under much higher pressures, has been investigated. In a wide range going from atmospheric pressure to values higher than 100 bar, no significant variations of the capacity factors were observed for the dyes used, and therefore, the information about retention mechanisms and solid/solution interface properties obtained from the spectral studies can be safely extrapolated to the real chromatographic systems. The results obtained indicate that the phenyl bonded silica shows a dipolarity/polarizability very similar to that of bare silica. For these two silica surfaces, the interactions of the dye and the stationary phase are independent of the mobile-phase composition. The C18 bonded silica has a significantly lower polar character and evidences two retention mechanisms depending upon the mobile-phase composition.
Highly Conductive and Ultrastretchable Electric Circuits from Covered Yarns and Silver Nanowires (2015)

Stretchable electronics, as a promising research frontier, has achieved progress in a variety of sophisticated applications. The realization of stretchable electronics frequently involves the demand for a stretchable conductor as an electrical circuit. However, it still remains a challenge to fabricate high-performance (working strain exceeding 200%) stretchable conductors. Here, we present for the first time a facile, cost-effective, and scalable method for manufacturing ultrastretchable composite fibers with a "twining spring" configuration: cotton fibers twining spirally around a polyurethane fiber. The composite fiber possesses a high conductivity up to 4018 S/cm, which remains as high as 688 S/cm at 500% tensile strain. In addition, the conductivity of the composite fiber (initial conductivity of 4018 S/cm) remains perfectly stable after 1000 bending events and levels off at 183 S/cm after 1000 cyclic stretching events of 200% strain. Stretchable LED arrays are integrated efficiently utilizing the composite fibers as a stretchable electric wiring system, demonstrating the potential applications in large-area stretchable electronics. The biocompatibility of the composite fiber is verified, opening up its prospects in the field of implantable devices. Our fabrication strategy is also versatile for the preparation of other specially functionalized composite fibers with superb stretchability.
Variable Impedance Transformer Models for use in Real-Time Security Analysis Functions (1983)

Traditional constant leakage reactance transformer models used in state estimation and load flow oriented real-time functions are not always appropriate for two-winding and three-winding transformers. In some cases the leakage reactance varies as much as fifty percent (50%) over the full transformer tap range. For three-winding transformers, the reactance for one of the legs of the model may change sign over the full transformer tap range. This paper presents the transformer models used for these variable leakage reactance transformers. Field state estimation results are included.
Design of a Clinical Knowledge Base for Heart Disease Detection (2007)

As people have interests in their health recently, development of medical domain application has been one of the most active research areas. One example of medical domain application is detection system for heart disease based on electrocardiogram (ECG) which records the electrical activity of the heart over time as wave form. However, detecting heart disease by using only ECG has some disadvantages, so detecting heart disease by using other resources is better way. In order to support detection system which uses several resources, knowledge of each resource domain should be defined. This research constructs knowledge base of ECG and heart disease using semantic web technology, proposes inference engine for heart disease detection, and implements prototype of this system.
Bridging the Gap between User Attributes and Service Policies with Attribute Mapping (2009)

People, companies, and public authorities can now have a strong online presence and a huge amount of interactions on the Internet, made possible by the impressive growth of the World Wide Web and of Web technologies. Many independent parties provide services and exchange information in a plural, dynamic, and open environment. This scenario, where interacting parties are often strangers, naturally brings to attribute based access control solutions, as traditional identity based systems are usually inadequate to large open environments. User attributes certified by external authorities, however, tend to be rather general purpose and to reflect a user point of view, thus they often do not coincide with the concepts that are relevant for the service. In this paper we propose a framework to decouple the user point of view and the service point of view on user attributes: following our model, the service access control policy can focus on the concepts that are relevant for the service logic, whereas a separate attribute mapping policy establishes the bridge between the two domains.
The Classification and Nomenclature of Viruses: Summary of Results of Meetings of the International Committee on Taxonomy of Viruses in Sendai, September 1984 (1986)

Meeting Reports/Abstracts| July 25 2008 The Classification and Nomenclature of Viruses: Summary of Results of Meetings of the International Committee on Taxonomy of Viruses in Sendai, September 1984 Subject Area: Further Areas F. Brown F. Brown President, International Committee on Taxonomy of Viruses Search for other works by this author on: This Site PubMed Google Scholar Intervirology (1986) 25 (3): 141–143. https://doi.org/10.1159/000149667 Article history Received: November 05 1985 Published Online: July 25 2008 Content Tools Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn Email Tools Icon Tools Get Permissions Cite Icon Cite Search Site Citation F. Brown; The Classification and Nomenclature of Viruses: Summary of Results of Meetings of the International Committee on Taxonomy of Viruses in Sendai, September 1984. Intervirology 1 March 1986; 25 (3): 141–143. https://doi.org/10.1159/000149667 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsIntervirology Search Advanced Search Article PDF first page preview Close Modal This content is only available via PDF. 1986Copyright / Drug Dosage / DisclaimerCopyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. You do not currently have access to this content.
Asymmetric induction in the cyclisation of o-allylphenol with chiral mercury(II) carboxylates. The effect of dimethyl sulphoxide (1973)

The reactions of o-allylphenol with mercury(II) salts of a range of chiral carboxylic acids, followed by reductive demercuration, give optically active 2,3-di-hydro-2-methylbenzofuran; optical yields are influenced by the addition of dimethyl sulphoxide (DMSO), the maximum effect occurring with 4 mol of DMSO per mol of carboxylate.
A Modified Round-Robin Load Balancing Algorithm Based on Content of Request (2018)

Cluster web servers emerged as a reliable and leading resource in internet infrastructure with the growing demands for web-based applications. The key point is to increase utilization of cluster web servers through an effective and fair load balancing strategy. In this paper, we proposed a new load balancing algorithm, which considers the load and performance information of nodes and the type of request to solve the problem of uneven distribution of load in cluster servers. Compared the common Round-Robin algorithm, the discussed method achieves a relatively optimum load balancing result.
花岗质深成岩体的分带性：—“分裂环状岩墙”假说（下） (1989)

矿物线理 这里还必须弄清早期火成线状排列与晚期构造发育之间的差异。 第一种矿物优选方位与析离体的形成及粘流有关。云母和钾长石巨晶产在析离体中或之上,并与之平行。 第二种矿物线理与其赋存的片理有关。其倾角一般很陡,有时能见到平行于应变椭球体
Dust devil formation (1972)

A review of the literature on observations of dust devils suggests that these whirls form like the rolling-up of a vertical vortex sheet when the stratification is slightly unstable. The linearized equations governing the stability of such flows are formulated. These are solved when the basic flow is a vertical vortex sheet in a fluid with uniform Brunt-Väisälä frequency. Also, the effects of a shear layer of finite width are considered. It is found how unstable stratification strongly intensifies the shear instability. Increase of stable stratification may decrease stability of some special disturbances.
Les sociétés pluri-professionnelles d'exercice confrontées à la responsabilité professionnelle, à l'assurance et à la déontologie (2020)

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