gebhart/patrepeval huggingface dataset:
The Determination of Micro Quantities of Isopropyl N-Phenylcarbamate (IPC) in Head Lettuce (1951)

Journal Article The Determination of Micro Quantities of Isopropyl N-Phenylcarbamate (IPC) in Head Lettuce Get access William E Bissinger, William E Bissinger Columbia-Southern Chemical Corporation, Barberton, Ohio Search for other works by this author on: Oxford Academic Google Scholar Robert H Fredenburg Robert H Fredenburg Columbia-Southern Chemical Corporation, Barberton, Ohio Search for other works by this author on: Oxford Academic Google Scholar Journal of Association of Official Agricultural Chemists, Volume 34, Issue 4, 1 November 1951, Pages 812–816, https://doi.org/10.1093/jaoac/34.4.812 Published: 08 February 2020
The 2.35 Å structure of the TenA homolog from<i>Pyrococcus furiosus</i>supports an enzymatic function in thiamine metabolism (2005)

TenA (transcriptional enhancer A) has been proposed to function as a transcriptional regulator based on observed changes in gene-expression patterns when overexpressed in Bacillus subtilis. However, studies of the distribution of proteins involved in thiamine biosynthesis in different fully sequenced genomes have suggested that TenA may be an enzyme involved in thiamine biosynthesis, with a function related to that of the ThiC protein. The crystal structure of PF1337, the TenA homolog from Pyrococcus furiosus, is presented here. The protomer comprises a bundle of alpha-helices with a similar tertiary structure and topology to that of human heme oxygenase-1, even though there is no significant sequence homology. A solvent-sequestered cavity lined by phylogenetically conserved residues is found at the core of this bundle in PF1337 and this cavity is observed to contain electron density for 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate, the product of the ThiC enzyme. In contrast, the modestly acidic surface of PF1337 shows minimal levels of sequence conservation and a dearth of the basic residues that are typically involved in DNA binding in transcription factors. Without significant conservation of its surface properties, TenA is unlikely to mediate functionally important protein-protein or protein-DNA interactions. Therefore, the crystal structure of PF1337 supports the hypothesis that TenA homologs have an indirect effect in altering gene-expression patterns and function instead as enzymes involved in thiamine metabolism.
Beyond the end of the line: Case reports of conversion from dextromoramide to other opiates within addiction maintenance treatment (2006)

Background: Interruption of supply of pharmaceutical opiates can cause major challenge to the continuity of management of opiate-dependent patients on maintenance treatment. Policy makers and practitioners need to learn lessons from the experiences of these occasional crises. Method: Through case report and clinical audit, we report on the opiate switch and dose conversion strategies with 14 patients previously receiving dextromoramide (Palfium®) as opiate addiction maintenance treatment. Results: Patients were switched to a wide range of different opiates, of which the most commonly-selected was morphine. Dose conversion ratios varied greatly between patients. Conclusion: Lessons need to be learnt from serendipitous experiments. In the absence of pre-existing guidance, great diversity of empirically derived practice occurred. Perhaps the most important lessons to be learnt are, first, that no rigid formula for conversion can be universally applied, second, that considerable between-subject variation will be observed and, third, that clinicians should consequently exercise increased caution with any existing tables being the beginning, and not the end, of the process of dose conversion.
Dysregulation of leukocyte gene expression in women with medication-refractory depression versus healthy non-depressed controls (2013)

These results support prior findings of dysregulation in immune genes, and provide preliminary evidence of dysregulation in purinergic and other ion channels in females with medication-refractory depression, and in transcription and growth factors in those with BPD. If replicated in future research examining protein levels as well as mRNA, these pathways could potentially be used to explore biological mechanisms of depression and to develop new drug targets.
Standardised PCR-based molecular epidemiology of tuberculosis (2007)

A population-based molecular epidemiology investigation has been undertaken to evaluate tuberculosis transmission and control in the Brussels-Capital Region (Belgium). All tuberculosis cases reported from January 2003 to December 2004 were investigated. In total, 536 Mycobacterium tuberculosis isolates (89% of culture-positive samples) were genotyped by the newly standardised 24 loci-based mycobacterial interspersed repetitive unit-variable number tandem-repeat typing, spoligotyping and IS6110 fingerprinting. Of all the patients, 30% were grouped based on strain clusters, suggesting a transmission index of 20%. An unsuspected outbreak entailing > or = 23 patients was evidenced by molecular typing analysis and confirmed by contact tracing. Foreign-born status accounted for 79% of the studied patients, including 37.9% illegal immigrants and asylum seekers. Among foreign-born patients, asylum seekers and illegal immigrants were significantly less abundant in strain clusters than settled residents. Tuberculosis in the Brussels-Capital Region is a bi-faceted problem, comprising both persisting recent transmission and "imported diseases". Molecular epidemiology based on real-time genotyping techniques has proven invaluable in better understanding tuberculosis transmission. However, it will most efficiently contribute to tuberculosis control when implemented in an integrated public health system.
Polarisierte Absorptionsspektren von Technetium(IV) und Rhenium(IV) in trigonalen Hexahalogenostannat(IV)-Einkristallen bei tiefer Temperatur / Polarized low temperature absorption spectra of technetium(IV) and rhenium(IV) in trigonal single crystals of hexahalogenostannates(IV) (1973)

Polarized absorption spectra of technetium(IV) and rhenium(IV) in trigonal single crystals of (C 2 H 5 NH 3 ) 2 [SnCl 6 ] and (C 2 H 5 NH 3 ) 2 [SnBr 6 ] have been measured in the range of 8000 to 2800 Å at 298 and 77 °K. The crystal point group is D 3d and the metal ions occupy sites of D 3d -symmetry too. The observed excited levels arise from both π 24 d 3 and π 23 d 4 configurations; the different temperature and polarisation dependence of d → d intra-shell and π → d metal reduction transitions is discussed. Experimental values of the parameters Dq (cubic) and υ (trigonal) are reported. The nephelauxetic ratio β 55 is evaluated from the 4 A 2g → 2 T 2g intrasubshell transitions. The electron transfer spectra suggest the optical electronegativity x opt = 2.3 for Tc(IV) and x opt = 2.1 for Re(IV).
Theoretical Research on the Reactive Power Compensation Converter (2015)

The article proposes a novel form of reactive power compensation converter, which adopts an inverter consisted of up and down symmetrical basic units and bidirectional switch. In this work, we have studied the working principle and operation characteristic of this circuit. According to the experimental results, this circuit has many superior performances, such as the output waveform traversing zero smoothly, the less waveform distortion and perfect stability of the frequency and magnitude.
ChemInform Abstract: COBALT(II) AND NICKEL(II) PERCHLORATE COMPLEXES WITH 2,6‐LUTIDINE N‐OXIDE (1977)

Abstract Beim Versuch, aus einer mit Triäthylorthoformiat dehydratisierten Lösung von Co(II)‐ oder Ni(II)‐perchlorat und Na‐tetraphenylborat mit einer sechsfach‐molaren Menge 2,6‐Lutidin‐N‐oxid Lutidin‐Komplexe als Tetraphenylborate zu isolieren, werden der funffach‐koordinierte Co(II)‐Komplex (I) und ein diamagnetisches Produkt der Zusammensetzung (II) erhalten.
Renal cortical and papillary blood flow in spontaneously hypertensive rats. (1988)

The present study examined whether an alteration in renal medullary hemodynamics is associated with the development of hypertension in the spontaneously hypertensive rat (SHR). The relationships between whole kidney, cortical and papillary blood flows, and renal perfusion pressure were compared in 3- to 5-, 6- to 9-, and 12- to 16-week-old SHR and Wistar-Kyoto rats (WKY). Cortical and papillary blood flows were similar in the different age groups of SHR and WKY over most of the range of perfusion pressure studied. Control papillary blood flows, determined at a renal perfusion pressure equal to the mean arterial pressure of each animal, were not significantly different in the 3- to 5- and 12- to 16-week-old SHR in comparison to values observed in age-matched WKY. In contrast, the control papillary blood flow was 30% lower in 6- to 9-week-old SHR in comparison to the value observed in WKY. Papillary blood flows were significantly less in all age groups of SHR than the corresponding flows measured in WKY when they were compared at equivalent renal perfusion pressures. These findings indicate that medullary vascular resistance is elevated even in very young SHR and suggest that alterations in vasa recta hemodynamics may participate in the development of hypertension by shifting the pressure-natriuresis relationship toward higher pressures.
Identification and characterization of polymorphisms at the HSA alpha1-acid glycoprotein (ORM*) gene locus in Caucasians (2002)

Human alpha1-acid glycoprotein (AGP) or orosomucoid (ORM) is a major acute phase protein that is thought to play a crucial role in maintaining homeostasis. Human AGP is the product of a cluster of at least two adjacent genes located on HSA chromosome 9. Using a range of restriction endonucleases we have investigated DNA variation at the locus encoding the AGP genes in a panel of healthy Caucasians. Polymorphisms were identified using BamHI, EcoRI, BglII, PvuII, HindIII, TaqI and MspI. Non-random associations were found between the BamHI, EcoRI, BglII RFLPs. The RFLPs detected with PvuII, TaqI and MspI were all located in exon 6 of both AGP genes. The duplication of an AGP gene was observed in 11% of the indiviuals studied and was in linkage disequilibrium with the TaqI RFLP. The identification and characterization of these polymorphisms will prove useful for other population and forensic studies.
Bimolecular and unimolecular contributions to the disparate self-chemical ionizations of <i>α</i>-Pinene and camphene isomers (2007)

The contributions of molecular and fragment ions toward the disparate self-chemical ionization (SCI) of alpha-pinene and camphene isomers were investigated. A kinetic model was constructed to predict the SCI outcomes for these two C(10)H(16) isomers. A major portion of the camphene molecular ions (isolated 500 ms after the 10 ms EI event at 24 eV) unimolecularly dissociated within 200 s of the ionization event. Conversely, under similar experimental conditions, the alpha-pinene molecular ions as well as the major fragment ions of alpha-pinene and camphene showed no unimolecular dissociation. The alpha-pinene and camphene molecular ions yielded product ions through two different reaction mechanisms (direct charge-transfer {CT} and indirect proton transfer {PT}). The isolated terpene fragment ions at m/z 93 and 121 reacted with their respective neutrals to produce [M + H](+). Proton affinity (PA) bracketing experiments, PA additivity schemes, and alkene PA versus adiabatic ionization energy (IE) linear correlation indicated that the PAs of camphene and alpha-pinene were comparable ( approximately 210 +/- 2 kcal x mol(-1)). The observed [M + H](+) SCI terpene ions were mainly the products of various fragment ion reactions.
Effects of lichen secondary metabolites on bacterial functions and biofilm formation (2008)

Long-living and slow growing lichens accumulate a diverse array of secondary metabolites in their symbiotic structures. These chemical products may participate in multiple functions of lichen biology, including defence against parasites. In fact, many previous studies showed various degrees of in vitro antibacterial effects of extracted secondary compounds pioneered by Burkholder et al. [1] and incorporation of lichen compounds as usnic acid into medical devices has been shown to inhibit bacterial biofilm formation on polymer surfaces [2]. However, further details are still unclear today and we have investigated the effect of some lichen compounds on biofilm formation looking for the interference with quorum sensing (QS) and influences on other bacterial functions. For this purpose we used highly purified lichen compounds and bacterial screening systems (Pseudomonas aeruginosa, Burkholderia cenocepacia, Vibrio fischeri and Chromobacterium violaceum). Initial studies focused on lactonic lichen compounds and revealed that protolichesterinic acid interferes with QS-systems of P. aeruginosa and B. cenocepacia. Vulpinic acid specifically inhibits production of the pigment violacein in Chromobacterium violaceum (also in Janthinobacterium), without effect on the QS-system. The potential utility of lichen compounds in bacterial biofilm regulation is highlighted.
Chain Segment Analysis (2015)

The work is aimed at a detailed analysis of impaired chain segments manufactured by welding and determining the cause of chain segment failure. The main interest was focused on the base material structure, the quality of weld joint, the heat treatment of the weldment, and the overall condition of the component after operating workload. The chain segments were investigated in terms of the microstructure by means of the light microscope, scanning electron microscope equipped with an energy dispersive microanalyser, and hardness measurement.
Scattering Transform for Matching Surgically Altered Face Images (2018)

The use of face as a biometric feature has been widely accepted and used in security and surveillance systems. Recent studies have made significant advancements to address various challenges in face recognition such as illumination, age, pose and disguise. Another important covariate is recognizing faces with pre-and-post facial plastic surgery. Facial plastic surgeries alter the geometry and texture of facial regions, the extent of which is dependent on both the number, and the type of surgeries performed. The increasing reach of plastic surgery and its expanding user base present an indispensable challenge that must be dealt with while devising robust face recognition systems. In this paper, we present Invariant Scattering transform based feature extraction to compute translation invariant representation at local and global levels that is stable against plastic surgery variations. The identification accuracy achieved by the proposed algorithm is over 97% at rank-10 on the IIITD plastic surgery face database.
Quantitation of dna damage in leukemia and solid tumor cells by flourescence enhancement assay. Abstr. (1980)

Herein, we developed a ligand-promoted Rh(III)-catalyzed C(sp<sup>3</sup>)-H thiolation of 8-methylquinolines. The effect of ligands on improving the activity of the catalytic centers has been studied in detail and proven to be significant. Various substituents are well tolerated under this reaction condition to provide potential precursors for organic synthesis. The mechanistic study suggests that the reaction may proceed through a five-membered rhodacycle intermediate via thiolation twice.
Detecting data races in Cilk programs that use locks (1998)

When two parallel threads holding no locks in common access the same memory location and at least one of the threads modifies the location, a "data race" occurs, which is usually a bug. This paper describes the algorithms and strategies used by a debugging tool, called the Nondeterminator-2, which checks for data races in programs coded in the Cilk multithreaded language. Like its predecessor, the Nondeterminator, which checks for simple "determinacy" races, the Nondeterminator-2 is a debugging tool, not a verifier, since it checks for data races only in the computation generated by a serial execution of the program on a given input.
Optical switching in nonlinear chiral distributed Bragg reflectors with defect layers: comment (2002)

We caution that the identification and subsequent replacement of an isotropic chiral medium with an electrically gyrotropic medium by Gilles and Tran [J. Opt. Soc. Am. B19, 630 (2002)] was premised on an incidental similarity. Although the subsequent results of Gilles and Tran reported in that paper are not affected, serious discrepancies would occur if their analysis were applied to different experimental geometries.
Small Noncytotoxic Carbon Nano‐Onions: First Covalent Functionalization with Biomolecules (2010)

Small carbon nano-onions (CNOs, 6-8 shells) were prepared in high yield and functionalized with carboxylic groups by chemical oxidation. After functionalization these nanostructures were soluble in aqueous solutions. 3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2 tetrazolium (MTS) tests showed excellent cytocompatibility of all CNOs analyzed at 30 and 300 microg mL(-1), so these carbon nanostructures can be safely used for biological applications. The first covalent functionalization of oxidized CNOs (ox-CNOs) with biomolecules, by using biotin-avidin interactions is reported here. Multilayers were prepared on a gold surface by layer-by-layer assembly and the process was monitored by surface plasmon resonance (SPR) spectroscopy and atomic force microscopy (AFM). Covalent binding of molecules to the short amine-terminated organosulfur monolayers was assessed by Fourier transform infrared spectroscopy using total attenuated reflactance mode (FT-IR/HATR).
An intelligent cooperative control system based on predictive fuzzy control (2004)

In this paper, we propose an intelligent control system which cooperates with human. This system gives power to reflect the will of the computer to human's operation. This system consists of predictive fuzzy controller and cooperation controller. The effectiveness of this system is confirmed by experiments that human operates a virtual vehicle.
N−H Insertion Reactions of Boc-Amino Acid Amides:  Solution- and Solid-Phase Synthesis of Pyrazinones and Pyrazines (2004)

A series of alpha-diazo-beta-ketoesters were reacted with Boc amino acid amides in the presence of rhodium octanoate catalyst. The resulting N-H insertion products were treated with acid, providing the 1,4-azine intermediates, which were oxidized by air to form the corresponding pyrazine-6-one products. The pyrazine-6-ones were further derivatized by N-alkylation or by conversion to the arylpyrazines using sequential bromination and Suzuki coupling reactions. [reaction: see text]
Production of Anhydrous Borax Using Microwave Heating (1995)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTProduction of Anhydrous Borax Using Microwave HeatingSidika Kocakusak, Juelide H. Koeroglu, Ekrem Ekinci, and Rasit TolunCite this: Ind. Eng. Chem. Res. 1995, 34, 3, 881–885Publication Date (Print):March 1, 1995Publication History Published online1 May 2002Published inissue 1 March 1995https://pubs.acs.org/doi/10.1021/ie00042a021https://doi.org/10.1021/ie00042a021research-articleACS PublicationsRequest reuse permissionsArticle Views198Altmetric-Citations6LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
ChemInform Abstract: Inhibitors of Cholesterol Biosynthesis. Part 4. trans‐6‐(2‐( Substituted‐quinolinyl)ethenyl/ethyl)tetrahydro‐4‐hydroxy‐2H‐pyran‐2‐ ones, a Novel Series of HMG‐CoA Reductase Inhibitors. (1991)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Postmeiotic Nuclear Behavior in Lentinus, Panus, and Neolentinus (1994)

We investigated nuclear behavior during basidiosporogenesis in Lentinus, Panus, and Neolentinus in an attempt to discover characters for taxonomic segregation of lentinoid-pleurotoid fungi. In Lentinus tigrinus and Panus lecomtei somatic hyphae are binucleate. Karyogamy and meiosis occur in the basidia, meiotic products migrate into spores and postmeiotic mitosis occurs; this is followed by back-migration of one nucleus from each spore into the basidium. Mature spores are consequently uninucleate and discharged basidia are quadrinucleate. In Neolentinus lepideus many somatic cells are multinucleate. Karyogamy, meiosis, and postmeiotic mitosis occur as in L. tigrinus and P. lecomtei, but there is no backmigration, mature spores are binucleate, and discharged basidia are anucleate. The patterns of nuclear behavior in L. tigrinus and P. lecomtei correspond to type C nuclear behavior as defined by Duncan and Galbraith, whereas that of Neolentinus corresponds to type D nuclear behavior. Lentinus and Panus cannot be distinguished on the basis of postmeiotic nuclear behavior, but both can be distinguished from Pleurotus which has been reported to have type A nuclear behavior sensu Duncan and Galbraith.
1-Chloro- and 1-Hydroxyphospholene-1-sulfides (1976)

A mixture of the two isomers of 1-chlorophospholene-1-oxide, obtained by a one-step, high-yield procedure reported previously 1 , upon reaction with P 4 S 10 was converted to a mixture of the two isomers of 1-chlorophospholene-1-sulfide which may be separated by spinning-band distillation. The thus obtained isomerically pure 1-chlorophospholene-1-sulfides were hydrolyzed to the corresponding 1-hydroxyphospholene-1-sulfides. These, as well as the precursor chloro compounds, were characterized by 1 H, 13 C, and 31 P NMR, mass spectrometry, and IR.
Purification, Characterization, and cDNA Cloning of a Galactose-specific C-Type Lectin from Drosophila melanogaster (1996)

We purified a lectin from a pupal extract of Drosophila melanogaster. This lectin agglutinated trypsinized and glutaraldehyde-fixed bovine red blood cells in the presence of calcium or magnesium. The hapten sugar of this lectin was galactose. The molecular mass of the intact lectin was determined to be 41 kDa, and it comprised 14- and 17-kDa subunits. The 17-kDa subunit was shown to be a glycosylated form of the 14-kDa subunit. Analysis of the cDNA for this lectin revealed that the 14-kDa subunit consists of 163 amino acid residues and contains all residues conserved in various C-type lectins. It was suggested that the Drosophila lectin and Sarcophaga lectin share some properties and function similarly in defense and development, but probably they are not structural homologues.