gebhart/patrepeval huggingface dataset:
Estrogen and progesterone together expand murine endometrial epithelial progenitor cells (2013)

Synchronous with massive shifts in reproductive hormones, the uterus and its lining the endometrium expand to accommodate a growing fetus during pregnancy. In the absence of an embryo the endometrium, composed of epithelium and stroma, undergoes numerous hormonally regulated cycles of breakdown and regeneration. The hormonally mediated regenerative capacity of the endometrium suggests that signals that govern the growth of endometrial progenitors must be regulated by estrogen and progesterone. Here, we report an antigenic profile for isolation of mouse endometrial epithelial progenitors. These cells are EpCAM(+) CD44(+) ITGA6(hi) Thy1(-) PECAM1(-) PTPRC(-) Ter119(-), comprise a minor subpopulation of total endometrial epithelia and possess a gene expression profile that is unique and different from other cells of the endometrium. The epithelial progenitors of the endometrium could regenerate in vivo, undergo multilineage differentiation and proliferate. We show that the number of endometrial epithelial progenitors is regulated by reproductive hormones. Coadministration of estrogen and progesterone dramatically expanded the endometrial epithelial progenitor cell pool. This effect was not observed when estrogen or progesterone was administered alone. Despite the remarkable sensitivity to hormonal signals, endometrial epithelial progenitors do not express estrogen or progesterone receptors. Therefore, their hormonal regulation must be mediated through paracrine signals resulting from binding of steroid hormones to the progenitor cell niche. Discovery of signaling defects in endometrial epithelial progenitors or their niche can lead to development of better therapies in diseases of the endometrium.
Fundamental physics on the JEM-EF - The Low Temperature Microgravity Physics Experiments Facility (2001)

The Low Temperature Microgravity Physics Experiments Facility (LTMPEF) takes advantage of the long-duration microgravity environment provided by the International Space Station and the payload accommodation of the Japanese Experiment Module's Exposed Facility (JEM-EF) to provide a NASA facility for fundamental physics research. Environmental factors influencing the quality of the experiments such as the vibration created within and by the Space Station, the charged-particle environment in low-Earth orbit, and the EMI environment will be discussed. Descriptions of the approved and candidate experiments will be presented as part of this presentation.
ChemInform Abstract: Chemistry of Coumarin Derivatives. Part 12. A Library of Pyranocoumarin Derivatives via a One‐Pot Three‐Component Hetero‐Diels—Alder Reaction. (2001)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
X-ray diffraction study of gadolinium stearate Langmuir-Blodgett films (2002)

The comparative structural studies of gadolinium stearate Langmuir-Blodgett films prepared with the use of two different subphases (aqueous solutions of gadolinium chloride and gadolinium acetate) have been performed by the methods of X-ray diffractometry. The films were applied onto single-crystal silicon substrates coated with a native-oxide layer either with the use of buffer molecular stearic-acid layers or without such layers. It was established that the films obtained with the use of gadolinium acetate and the preliminarily formed buffer layers are, in fact, single-phase Y-type films with highly ordered molecular structure, and the thickness of the bimolecular layer d = (51.3 ± 0.5) Å.
Inhibition of the neutrophil oxidative burst by sphingoid long-chain bases: role of protein kinase C in the activation of the burst (1986)

The neutrophil oxidative burst is triggered by a variety of both particulate (opsonized zymosan) and soluble agonists (formylmethionylleucylphenylalanine (FMLP), arachidonate, short-chained diacylglycerols (DAG) and phorbol myristate acetate (PMA)). The authors show that the long-chain lipid bases sphinganine and sphingosine block activation of the burst in human neutrophils. Inhibition is reversible, does not alter cell viability, and does not affect phagocytosis. The inhibition affects the activation mechanism rather than the NADPH-oxidase enzyme. The structural requirements for inhibition include a hydrophobic carbon chain and an amino-containing headgroup, and the naturally occurring erythro sphinganine was more potent than the threo isomer. Activation of the oxidative burst by a variety of agonists was blocked by the same concentration of sphinganine indicating a common inhibited step. The authors suggest that the common step is protein kinase C, as evidenced by the following: 1) long-chain bases inhibit PKC in a micelle reconstituted system, 2) PMA-induced phophorylation is inhibited by sphinganine, and 3) sphinganine competes with (/sup 3/H)-phorbol dibutyrate for its cytosolic receptor (i.e. protein kinase C). The authors suggest that sphingoid long-chain bases play a role in the cellular regulations.
Effects of heavy metals and other trace elements on the fermentative activity of the rumen microflora and growth of functionally important rumen bacteria (1978)

The inhibitory effects of high concentrations of essential and non-essential trace elements were tested on the rumen microflora using the rate of fermentation in vitro as the assay. The elements (and the concentration causing 50% inhibition) in decreasing order of toxicity were Hg2+ (20 microgram/ml), Cu2+ (21 microgram/ml), Cr6+ (70 microgram/ml), Se4+ (73 microgram/ml), Ni2+ (160 microgram/ml), Cd2+ (175 microgram/ml), As3+ (304 microgram/ml) and As5+ (1610 microgram/ml). The elements tested that were either weak or noninhibitory at concentrations greater than 400 microgram/ml included Zn2+, Cr2+, Fe2+, Mn2+, Pb2+, and Co2+. Methylmercury was as inhibitory as mercuric chloride to the fermentation. When the inhibitory effect of Cd2+ was tested on separated bacterial and protozoal fractions, it was more inhibitory to the bacteria. The inhibitory effects of trace elements were also determined for a number of axenic cultures of rumen bacteria. The bacteria which most frequently exhibited the greatest sensitivity were Bacteroides succinogenses, Ruminococcus albus, Bacteroides amylophilus, and Eubacterium ruminantium. Those often exhibiting intermediate sensitivities included Butyrivibrio fibrisolvens, Selenomonas ruminantium, and Megasphera elsdenii, while Streptococcus bovis was very refractory to all elements tested. Rumen fluid provided a modest protective effect for the bacteria.
Plant Disease Russell Stevens Fundamentals of Plant Pathology Daniel A. Roberts Carl W. Boothroyd (1974)

Journal Article Plant Disease; Fundamentals of Plant Pathology Get access Plant Disease, by Stevens Russell. The Ronald Press Co., New York, 1974, 459 p., illus., $11.95 (73-77863).Fundamentals of Plant Pathology, by Roberts Daniel A. Boothroyd Carl W.. W. H. Freeman and Co., San Francisco, Calif., 1972, 402 p., illus., $15.00 (77-169737). George L. McNew George L. McNew Boyce Thompson Institute, Yonkers, NY 10701 Search for other works by this author on: Oxford Academic Google Scholar BioScience, Volume 24, Issue 12, December 1974, Page 727, https://doi.org/10.2307/1297091 Published: 01 December 1974
Association of the <i>MC4R</i> V103I Polymorphism With the Metabolic Syndrome: The KORA Study (2008)

Our representative study of well-phenotyped Europeans is the first to describe the association of the MC4R V103I with the metabolic syndrome and with a nutrient-related phenotype. Our data support the idea that this polymorphism plays a role in appetite regulation that not only affects BMI, but also other features of the metabolic syndrome. It further establishes that the association of the MC4R V103I with obesity and related phenotypes is genuine.
Efficient irradiance normal mapping. (2010)

Figure 1: A typical game scene using standard light mapping (left) and irradiance normal mapping using the H-basis without (middle) and with (right) textured albedo. Irradiance normal mapping is a method to combine two popular techniques, light mapping and normal mapping, and is used in games such as Half-Life 2 or Halo 3. This combination allows using low-resolution light caching on surfaces with only a few coefficients which are evaluated by normal maps to render spatial high-frequency changes in the lighting. Though there are dedicated bases for this purpose such as the Half-Life 2 basis, higher order basis functions such as quadratic Spherical Harmonics are needed for an accurate representation. However, a full spherical basis is not needed since the irradiance is stored on the surface of a scene. In order to represent the irradiance signals efficiently, we propose a novel polynomial, hemispherically orthonormal basis function set that is specifically designed to carry a directional irradiance signal on the hemisphere and which makes optimal use of the number of coefficients. To compare our results with previous work, we analyze the relations and attributes of previously proposed basis systems and show that 6 coefficients are sufficient to accurately represent an irradiance signal on the hemisphere. To create the necessary irradiance signals, we use Spherical Harmonics as an intermediate basis due to their fast filtering capabilities.
Some Issues in the Design of an Extensible Operating System (1999)

Extensible operating systems are designed around the principle that the service and performance requirements of all applications cannot be met in advance by any operating system. Consequently, an extensible system strives to provide a dynamic software infrastructure which allows system interfaces and implementations to be adapted or replaced to best serve application demands. However, realizing this goal poses a number of unique problems which must be addressed. Foremost among these are:
Respiratory control in cytochrome oxidase vesicles is correlated with the rate of internal electron transfer (1992)

Cytochrome c oxidase, after reconstitution into phospholipid vesicles, displays respiratory control. This appears as an inhibition of substrate oxidation (cytochrome c) or reduction (O2) rates which, in the first few turnovers, can be largely removed upon addition of valinomycin, a specific K+ carrier. We report experiments designed to measure directly the internal electron transfer leading to the reduction of cytochrome a3/CuB, in the presence and the absence of a membrane potential. The results suggest that, after the complete oxidation and partial re-reduction of the protein, electron transfer to the binuclear site is valinomycin-sensitive, i.e. is inhibited by the membrane potential. The first-order rate constants calculated in the absence and presence of valinomycin were 0.5-0.6 and 5-6 s-1 respectively. Kinetic analysis of the reduction process is consistent with the conclusion that the membrane potential is below the critical threshold until the first electron is transferred to the cytochrome a3/CuB site. Furthermore, the respiratory control ratio obtained from the dependence of the internal electron transfer rate constant on valinomycin is always higher (by factor of 2) than that measured under turnover conditions either polarographically or spectrophotometrically. Two possible interpretations of this discrepancy are discussed.
The synthesis and optical characterization of well aligned ZnO nanorods using seed layer of Mn3O4 nanoparticles (2014)

In this study, vertically aligned ZnO nanorods were fabricated by hydrothermal growth method using manganese oxide Mn3O4 nanoparticles as a seed layer. X-ray diffraction and Raman studies have shown the nano meter size of Mn3O4 nanoparticles. ZnO nanorods were characterized by field emission scanning electron microscopy and X-ray diffraction techniques. The prepared ZnO nanorods are highly dense, uniform and verily aligned and possess good crystal quality. Photoluminescence analysis has demonstrated that the ZnO nanorods exhibit deep level emission in green region due to oxygen vacancy related emission and the orange/red region is resulted due to interstitial oxygen defects related emission. This method for the fabrication of well aligned ZnO nanorods can be adapted for the development of optoelectronic devices.
TGF-β3-induced Palatogenesis Requires Matrix Metalloproteinases (2001)

Cleft lip and palate syndromes are among the most common congenital malformations in humans. Mammalian palatogenesis is a complex process involving highly regulated interactions between epithelial and mesenchymal cells of the palate to permit correct positioning of the palatal shelves, the remodeling of the extracellular matrix (ECM), and subsequent fusion of the palatal shelves. Here we show that several matrix metalloproteinases (MMPs), including a cell membrane-associated MMP (MT1-MMP) and tissue inhibitor of metalloproteinase-2 (TIMP-2) were highly expressed by the medial edge epithelium (MEE). MMP-13 was expressed both in MEE and in adjacent mesenchyme, whereas gelatinase A (MMP-2) was expressed by mesenchymal cells neighboring the MEE. Transforming growth factor (TGF)-beta3-deficient mice, which suffer from clefting of the secondary palate, showed complete absence of TIMP-2 in the midline and expressed significantly lower levels of MMP-13 and slightly reduced levels of MMP-2. In concordance with these findings, MMP-13 expression was strongly induced by TGF-beta3 in palatal fibroblasts. Finally, palatal shelves from prefusion wild-type mouse embryos cultured in the presence of a synthetic inhibitor of MMPs or excess of TIMP-2 failed to fuse and MEE cells did not transdifferentiate, phenocopying the defect of the TGF-beta3-deficient mice. Our observations indicate for the first time that the proteolytic degradation of the ECM by MMPs is a necessary step for palatal fusion.
Evaluation of flow properties and rock microstructure in sandstones with a complex pore system using x-ray microcomputed tomography (2017)

Formation absolute permeability is the key reservoir parameter that indicates how efficient fluids flow to the wellbore through the formation pore network. It is important to understand the controls affecting pore-scale fluid flow. Complex tight microporous systems, as encountered in Middle Jurassic siliciclastic reservoirs of this study, render permeability prediction from logs challenging and result in a poor match with conventional core analysis (CCAL). Pore-scale permeability controls need to be addressed as part of the pre-testing petrophysical analysis, but not post-evaluation to be of value in exploration drilling. The objective of this study is to improve the permeability model for the Middle Jurassic succession in a representative well (termed “well A”). A proper evaluation of the pore structure porosity types and hydraulic tortuosity leads to better permeability estimates by adding constraints to the permeability model. X-ray micro CT-scan technology provides 3D high resolution images (2-5 microns) that resolve the 3D pore structure in rocks and enables us to quantify porosity and hydraulic tortuosity. Based in the comparison of six permeability models, the Kozeny-Carman model, which uses porosity, average grain size and hydraulic tortuosity to estimate permeability, proved to provide the most accurate petrophysical analysis. Modeling results show good agreement with well tests that indicate a tight formation, contrary to conventional core analysis that yielded permeability values an order of magnitude higher than permeability logs. Other data from thin section analyses and mercury injection capillary pressure (MICP) pore throat distributions support the modeling results. This study emphasizes the application of micro CT-scan technology in formation evaluation and the estimation of petrophysical input parameters for accurate permeability prediction in a timely and cost-effective manner. Presentation Date: Wednesday, September 27, 2017 Start Time: 2:15 PM Location: Exhibit Hall C, E-P Station 4 Presentation Type: EPOSTER
Transition metal hydroborate complexes. V. Crystal structure of tetrahydroboratobis(cyclopentadienyl)titanium(III) (1973)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTTransition metal hydroborate complexes. V. Crystal structure of tetrahydroboratobis(cyclopentadienyl)titanium(III)K. M. Melmed, D. Coucouvanis, and S. J. LippardCite this: Inorg. Chem. 1973, 12, 1, 232–236Publication Date (Print):January 1, 1973Publication History Published online1 May 2002Published inissue 1 January 1973https://doi.org/10.1021/ic50119a051RIGHTS & PERMISSIONSArticle Views159Altmetric-Citations66LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (685 KB) Get e-Alerts Get e-Alerts
Continuous preparation of cytocompatible poly(2-methacryloyloxyethyl phosphorylcholine) microcapsule for cell immobilization using microfluidics (2011)

We have studied the preparation of 2-methacryloyloxyethyl phosphorylcholine (MPC) polymer microcapsules as a carrier for living cells by two microfluidic methods as follows: (i) By photoinduced radical polymerization of MPC, the microcapsules with ca. 85 μm in the diameter were obtained, however, they had low mechanical strength to maintain their shape. (ii) By cross-linking of poly(MPC-co-n-butyl methacrylate-co-4-vinylphenyl boronic acid) (PMBV) and poly(vinyl alcohol) (PVA), oval-shaped capsules were obtained. Even the capsules were not spherical, the size of the capsules were uniformed. Resultant capsules had mechanical strength enough for maintaining their shape. Sedimentation of the capsules, leading to collapse and coalescence, was prevented by using silicone oil as collection medium. The capsules prepared by the cross-linking method would be suitable candidate for microsized cell carriers and cell culture vessels because the MPC polymers possess highly cytocompatibility.
A broadband microstrip to waveguide transition for FR4 multilayer PCBs up to 50 GHz. (2002)

A broadband microstrip-to-waveguide transition has been studied and tested for low-cost microwave circuits on FR4 multilayer boards having an internal thick metal plate (1). It is obtained, at first, milling a slot in a thick metal plate. Subsequently the PCB is built up, using standard PCB process, inserting the thick metal plate as the second layer. In this way the slot results filled with FR4 prepreg. A further simple milling process removes the lower layers up to the thick metal plate and creates a part of the waveguide transformer and an area for plate to metal housing connection. The transition integration in the multilayer is obtained just fixing the board on the metal housing which includes the rest of the transformer and the waveguide. Moreover, as the transition shows low sensitivity to manufacturing tolerances, the above process is characterised by high reliability and reproducibility.
High-T/sub c/ superconducting EuBa/sub 2/Cu/sub 3/O/sub y/ thin films and MgO and YAlO/sub 3/ for coplanar devices (1993)

The authors have studied the microwave properties of high-T/sub c/ superconducting EuBa/sub 2/Cu/sub 3/O/sub y/ (EBCO) films on MgO and YAlO/sub 3/ substrates with low dielectric constants ( in =10 and 16, respectively), and a low loss tangent (tan delta <10/sup -5/). Measurements of surface resistance R/sub s/ at 50 GHz in a cavity show that EBCO films exhibit low R/sub s/ values (77 K) of 2-10 m Omega . A microstructural study using transmission electron microscopy showed that crystal defects related to the in-plane misorientation are observed for films with higher R/sub s/ values. The R/sub s/ values of the patterned films were measured in a coplanar transmission line resonator. A typical value for patterned films was 28 mu Omega at 4 GHz and 28 K.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
A Highly Linear Broadband Variable Gain LNA for TV Applications (2007)

A broadband variable-gain low noise amplifier with triple output for TV tuners has been demonstrated in a 0.18 μm SiGe technology. The gain varies continuously from 27 dB to -28 dB and has better than 1 dB precision over a 1GHz bandwidth. At 27 dB gain the amplifier shows 6.5 dB NF, 82 dBmV OIP3 and 121 dBmV OIP2. OIP3 is above 73 dBmV down to -21 dB gain. With all three outputs enabled the circuit draws 170 mA from a 3.3V supply.
Chaetoglobins A and B, two unusual alkaloids from endophytic Chaetomium globosum culture (2008)

Chaetoglobins A (1) and B (2), two azaphilone alkaloid dimers with an unprecedented skeleton, were characterized from an endophytic fungus Chaetomium globosum with the former ascertained to be a significant cytotoxin valuable for anti-tumor drug discovery.
Mo<sub>6</sub>S<sub>8</sub>Electrochemical Transfer Junction for Selective Extraction of Co<sup>2+</sup>-Ions from Their Mixture with Ni<sup>2+</sup>-Ions (2013)

International audience
Using the web as an implicit training set (2005)

Recent work has shown that very large corpora can act as training data for NLP algorithms even without explicit labels. In this paper we show how the use of surface features and paraphrases in queries against search engines can be used to infer labels for structural ambiguity resolution tasks. Using unsupervised algorithms, we achieve 84% precision on PP-attachment and 80% on noun compound coordination.
Study of non-solitonic blue-green radiation generated in mm-long photonic crystal fibers (2006)

We demonstrate highly-efficient generation of green-blue light using 20-fs femtosecond laser pulses propagating in short highly-nonlinear photonic crystal fibres. Three 5-mm-long fibres with different zero dispersion wavelengths were pumped by Ti:Sapphire pulses centred around 800-nm, and the relevant spectral characteristics of the generated radiation were studied as a function of pulse energy and chirp. In addition to the non-solitonic green-blue light, a well-defined infrared peak was simultaneously observed that follows the same power and wavelength dependence found on the green-blue peak. This work shows that short photonic crystal fibres can be used as an efficient source of ultrashort blue-green pulses (and possibly near-IR pulses) since linear dispersion (and consequent temporal broadening) and absorption of fused silica are minimized when using short fibres.