gebhart/patrepeval huggingface dataset:
A Procedure for Robust Design: Minimizing Variations Caused by Noise Factors and Control Factors (1996)

In this paper, we introduce a small variation to current approaches broadly called Taguchi Robust Design Methods. In these methods, there are two broad categories of problems associated with simultaneously minimizing performance variations and bringing the mean on target, namely, Type I—minimizing variations in performance caused by variations in noise factors (uncontrollable parameters). Type II—minimizing variations in performance caused by variations in control factors (design variables). In this paper, we introduce a variation to the existing approaches to solve both types of problems. This variation embodies the integration of the Response Surface Methodology (RSM) with the compromise Decision Support Problem (DSP). Our approach is especially useful for design problems where there are no closed-form solutions and system performance is computationally expensive to evaluate. The design of a solar powered irrigation system is used as an example.
Developmental regulation of the gene for formate dehydrogenase in Neurospora crassa (1993)

We have isolated and characterized a gene, fdh, from Neurospora crassa which is developmentally regulated and which produces formate dehydrogenase activity when expressed in Escherichia coli. The gene is closely linked (less than 0.6 kb apart) to the leu-5 gene encoding mitochondrial leucyl-tRNA synthetase; the two genes are transcribed convergently from opposite strands. The expression patterns of these genes differ: fdh mRNA is found only during conidiation and early germination and is not detectable during mycelial growth, while leu-5 mRNA appears during germination and mycelial growth. The structure of the fdh gene was determined from the sequence of cDNA and genomic DNA clones and from mRNA mapping studies. The gene encodes a 375-amino-acid-long protein with sequence similarity to NAD-dependent dehydrogenases of the E. coli 3-phosphoglycerate dehydrogenase (serA gene product) subfamily. In particular, there is striking sequence similarity (52% identity) to formate dehydrogenase from Pseudomonas sp. strain 101. All of the residues thought to interact with NAD in the crystal structure of the Pseudomonas enzyme are conserved in the N. crassa enzyme. We have further shown that expression of the N. crassa gene in E. coli leads to the production of formate dehydrogenase activity, indicating that the N. crassa gene specifies a functional polypeptide.
[Retracted] A Deep Learning‐Based TE Method for MSs’ Mental Health Analysis (2022)

Teaching evaluation (TE) is of great significance in education and can judge the value and appropriateness of the curriculum, which is a distinguished part of the educational work. Compared with other courses focusing on imparting knowledge, mental health not only imparts psychological knowledge but also cultivates Marxism students' (MSs) ability to adjust psychology and maintain mental health. Therefore, the evaluation of this course has a special character. As the unity of scientific world outlook and values, Marxism can promote students' mental health. When assessing students' ability to maintain mental health, the influence of Marxism should be taken into account. In this study, we first established an evaluation index system in line with the actual mental health considering the influence of Marxism and put forward a deep memory network with prior information (PI-DMN) to realize the aspect-based sentiment analysis (ABSA) of the student evaluation text. Combined with students' scoring of the course, the sentiment analysis results are used as the input dataset of LSTM model to realize the TE of mental health course. The data analysis exposes that Marxism can promote mental health, and the empirical analysis reveals that the accuracy of TE can be improved by considering the sentiment analysis of comment texts and can also be improved to a certain extent after aspect labeling of the dataset.
THEORETICAL ASPECTS OF THE U.V. INACTIVATION OF PROTEINS CONTAINING DISULFIDE BONDS (1967)

ABSTRACT Equations are proposed for the estimation of quantum yields for cystine destruction and disulfide protein inactivation during u.v.‐irradiation in acidic and neutral solutions. The formulas permit a discussion of energy transfer from excited aromatic amino acids to cystines and/or of chemical reactions between excited tryptophans or tyrosines and cystines. The results are discussed with regard to general aspects of the photo‐biochemistry of enzymes.
Current status of large scale integration technology (1967)

Considerable progress has been made in large scale integration technology during the past year. Many of the goals, which were theoretical assumptions last year, are now well along the way to reality. Accomplishments range from basic materials processing improvements to systems architecture innovations. While this paper will concentrate on large scale integration technology achievements, we shall also focus some attention on progress in significant related areas.
A study of colour emotion and colour preference. Part I: Colour emotions for single colours (2004)

Abstract This article classifies colour emotions for single colours and develops colour‐science‐based colour emotion models. In a psychophysical experiment, 31 observers, including 14 British and 17 Chinese subjects assessed 20 colours on 10 colour‐emotion scales: warm–cool, heavy–light, modern–classical, clean–dirty, active–passive, hard–soft, tense–relaxed, fresh–stale, masculine–feminine, and like–dislike. Experimental results show no significant difference between male and female data, whereas different results were found between British and Chinese observers for the tense–relaxed and like–dislike scales. The factor analysis identified three colour‐emotion factors: colour activity, colour weight, and colour heat. The three factors agreed well with those found by Kobayashi and Sato et al. Four colour‐emotion models were developed, including warm–cool, heavy–light, active–passive, and hard–soft. These models were compared with those developed by Sato et al. and Xin and Cheng. The results show that for each colour emotion the models of the three studies agreed with each other, suggesting that the four colour emotions are culture‐independent across countries. © 2004 Wiley Periodicals, Inc. Col Res Appl, 29, 232–240, 2004; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/col.20010
Synthesis of 2-Substituted Benzothiazoles from 1-Iodo-2-nitrobenzenes by a Copper-Catalyzed One-Pot Three-Component Reaction (2013)

A novel method was developed for synthesizing 2-substituted 1,3-benzothiazoles through a copper-catalyzed, one-pot, three-component reaction of a 1-iodo-2-nitrobenzene with sodium sulfide and an aldehyde.
A Reliable Fusion Positioning Strategy for Land Vehicles in GPS-Denied Environments Based on Low-Cost Sensors (2016)

How to achieve reliable and accurate positioning performance using low-cost sensors is one of the main challenges for land vehicles. This paper proposes a novel fusion positioning strategy for land vehicles in GPS-denied environments, which enhances the positioning performance simultaneously from the sensor and methodology levels. It integrates multiple complementary low-cost sensors not only incorporating GPS and microelectromechanical-based inertial measurement unit, but also a “virtual” sensor, i.e., a sliding-mode observer (SMO). The SMO is first synthesized based on nonlinear vehicle dynamics model to estimate vehicle state information robustly. Then, a federated Kalman filter (FKF) is designed to fuse all sensor information, which can easily isolate and accommodate such sensor failures as GPS ones due to its decentralized filtering architecture. Further, a hybrid global estimator (HGE) is constructed by augmenting the FKF with a grey predictor, which has the advantages of dealing with the systems with uncertain or insufficient information. The HGE works in the update mode when there is no GPS failure, whereas it switches to the prediction mode in case of GPS outage to realize accurate and reliable positioning. The experimental results validate the effectiveness and reliability of the proposed strategy.
A Pro250Arg substitution in mouse Fgfr1 causes increased expression of Cbfa1 and premature fusion of calvarial sutures (2000)

Pfeiffer syndrome is a classic form of craniosynostosis that is caused by a proline-->arginine substitution at amino acid 252 (Pro252Arg) in fibroblast growth factor receptor 1 (FGFR1). Here we show that mice carrying a Pro250Arg mutation in Fgfr1, which is orthologous to the Pfeiffer syndrome mutation in humans, exhibit anterio-posteriorly shortened, laterally widened and vertically heightened neurocraniums. Analysis of the posterior and anterior frontal, sagittal and coronal sutures of early post-natal mutant mice revealed premature fusion. The sutures of mutant mice had accelerated osteoblast proliferation and increased expression of genes related to osteoblast differentiation, suggesting that bone formation at the sutures is locally increased in Pfeiffer syndrome. Of note, dramatically increased expression of core-binding transcription factor alpha subunit type 1 (Cbfa1) accompanied premature fusion, suggesting that Cbfa1 may be a downstream target of Fgf/Fgfr1 signals. This was confirmed in vitro, where we demonstrate that transfection with wild-type or mutant Fgfr1 induces Cbfa1 expression. The induced expression was also observed using Fgf ligands (Fgf2 and Fgf8). These studies provide direct genetic evidence that the Pro252Arg mutation in FGFR1 causes human Pfeiffer syndrome and uncovers a molecular mechanism in which Fgf/Fgfr1 signals regulate intramembraneous bone formation by modulating Cbfa1 expression.
A Study on Utilization Policy of Empty Classrooms in Elementary School (1995)

The primary purpose of this study is to suggest the policy for the effective utilization of empty classrooms in elementary school. The empty classroom in this study means the classroom that is not used now since the number of students decreases, but can be usable for other needs in future. The following results are obtained through this survey; 1) about forty percent of classrooms are empty classrooms, 2) the ratio of empty classrooms is higher in urban area than rural area, 3) the smaller the size of classroom is, the higher the ratio is, and 4) 56.5% of the schools have one to three empty classrooms and 30.0% have four to six empty classrooms. In conclusion it is suggested that 1) the reutilization plan of empty classrooms be established according to particular situation of each school, 2) the government develop the guidelines for reutilization and administrative procedures for renewal, 3) the reutilization plan be established from the view point of the quality improvement of schooling, and 4) the enlargement and rearranagemt of learning space be considerd when reutilization is planned.
A Neo-Reflective Wrist Pulse Oximeter (2014)

This paper relates to a genuine wrist pulse oximeter, which is a noninvasive medical device that can measure the pulse rate and oxygen saturation level in a person’s blood. The device is novel due to its innovative design. It is a new type of reflective oximeter, which has a concave structure for housing the optical source and sensor. The neo-reflective sensor module of the device is designed to send the sensor data to a nearby intelligent mobile phone using wireless data transmission. The pulse oximeter has been developed and calibrated, and the calibration curve was analyzed. The innovative design of this pulse oximeter would enable the user to wear the low-cost device on one wrist continuously throughout the day, without the inconvenience of a conventional finger pulse oximeter.
PURGING OF NATURAL SALT‐STOCK PICKLE FERMENTATIONS TO REDUCE BLOATER DAMAGE (1977)

ABSTRACT Efficient nitrogen‐purging systems were developed for maintaining low CO 2 concentrations in commercial salt‐stock pickle fermentations. The successful systems tested were those in which a gas diffuser with a very small pore size was used to purge the brine while the brine was being circulated. The use of these systems dramatically reduced the incidence of severe bloaters in salt‐stock pickles of large diameter. Specific recommendations are included for the design and use of a purging apparatus.
Protective effect of astaxanthin on human retinal pigment epithelial cells injured by hydrogen peroxide (2015)

AIM: To investigate the protective effect of astaxanthin(AST)on human retinal pigment epithelial(RPE)cells against oxidative damage induced by hydrogen peroxide(H<sub>2</sub>O<sub>2</sub>). METHODS:Human RPE cells were subcultured, cell activity was detected by MTT, rate of apoptosis was detected by flow cytometry and cell ultrastructure changes were observed under transmission electron microscope. RESULTS:MTT results showed that cell activity elevated to(53.66%±3.25% and 70.43%±2.38% after 10<sup>-8</sup>mol/L and 10<sup>-4</sup>mol/L AST treated. The difference had statistically significant(<i>P</i><0.05)compared with oxidative injury group(38.76%±3.74%). Flow cytometry results showed that the apoptosis rate of RPE cells decreased to 30.23%±1.91% and 12.58%±2.12% in AST pretreated group, the difference was significant(<i>P</i><0.05)compared with oxidative injury group(42.50%±1.94%); Electron microscopy showed that the morphology of cells gradually improved accompanied with the concentration of AST elevated. CONCLUSION:AST may inhibit hydrogen peroxide-induced apoptosis of RPE cells, it can provide reliable evidence for pursue effective medicine to prevent and treat retina injury.
An extractive supervised two-stage method for sentence compression (2010)

We present a new method that compresses sentences by removing words. In a first stage, it generates candidate compressions by removing branches from the source sentence’s dependency tree using a Maximum Entropy classifier. In a second stage, it chooses the best among the candidate compressions using a Support Vector Machine Regression model. Experimental results show that our method achieves state-of-the-art performance without requiring any manually written rules. 1
A case of granulomatous rosacea successfully treated with pimecrolimus cream (2008)

A 43-year-old male attended with lesions on his face that had been present for 3 months. On dermatological examination, multiple papules and pustules were seen on the forehead, nose, bilateral cheeks and lower eyelids. The patient used systemic clindamycin and doxycycline and topical benzoyl peroxide therapies, but the lesions did not regress. Routine laboratory tests were normal. Histopathological examination of the lesions confirmed the diagnosis of granulomatous rosacea. Pimecrolimus cream 1% was applied to the lesions. The regression of lesions began in the first month and complete improvement was observed at the end of the fourth month of therapy. Rosacea is a chronic, inflammatory skin disorder characterized by remissions and relapses. Although it is known that the disease is a treatable disorder, it may be resistant to standard therapies and there is a need for new therapy alternatives in some patients. We present a case of granulomatous rosacea successfully treated with pimecrolimus cream and believe that pimecrolimus may be a good alternative for the treatment of granulomatous rosacea.
Crystallographic Orientation of Zinc Oxide Films Deposited by Triode Sputtering (1969)

Zinc oxide films for thin film piezoelectric transducer applications have been deposited by triode sputtering onto gold film surfaces. Films sputtered under relatively hydrocarbon-free conditions showed the “normal” orientation with the c axis perpendicular to the substrate surface. The addition of hydrocarbon vapors to the sputtering gas at the beginning of the deposition resulted in films at least partly oriented with the c-axis parallel to the substrate surface, and the simultaneous application of a reverse bias to the substrate holder produced films essentially completely oriented with this parallel orientation. Under oblique deposition conditions the average c axis direction in the film plane was directed towards the target, yielding good piezoelectric shear mode transducers with a uniform polarization. It is suggested that the hydrocarbon vapors polymerize in the discharge, covering the substrate with an organic film on which zinc oxide grows with the parallel orientation, and that alignment of the c-axis in the oblique deposition arises from preferential growth of crystallites oriented with their c axis towards the target.
Security and Privacy in Decentralized Energy Trading Through Multi-Signatures, Blockchain and Anonymous Messaging Streams (2016)

Smart grids equipped with bi-directional communication flow are expected to provide more sophisticated consumption monitoring and energy trading. However, the issues related to the security and privacy of consumption and trading data present serious challenges. In this paper we address the problem of providing transaction security in decentralized smart grid energy trading without reliance on trusted third parties. We have implemented a proof-of-concept for decentralized energy trading system using blockchain technology, multi-signatures, and anonymous encrypted messaging streams, enabling peers to anonymously negotiate energy prices and securely perform trading transactions. We conducted case studies to perform security analysis and performance evaluation within the context of the elicited security and privacy requirements.
Evaluation of the Affirm Ambient Temperature Transport System for the Detection and Identification of <i>Trichomonas vaginalis</i> , <i>Gardnerella vaginalis</i> , and <i>Candida</i> Species from Vaginal Fluid Specimens (2001)

The objective of this study was to measure the performance of the Affirm Ambient Temperature Transport System (ATTS) over time and to estimate the length of time the system can preserve a vaginal specimen containing the three common organisms causing vaginitis: Trichomonas vaginalis, Candida species, and Gardnerella vaginalis (one of the causative agents of bacterial vaginosis). Women with symptoms of vaginitis presenting to one of three clinical centers were evaluated over a 4- to 8-week period. Four simultaneously obtained swabs were collected and tested by the Affirm VPIII assay at time zero with and without a preservative reagent, at 24 h with reagent, and at either 48 or 72 h with reagent. For each of the three organisms, Trichomonas, Gardnerella, and Candida, positivity at each time point was evaluated and compared to that at reference time zero with and without the ATTS. A total of 940 specimens were obtained from the three clinical sites. Eight hundred three were positive for one or more of the three organisms. Gardnerella had the highest overall positive rate (62%), followed by Candida with 18% and Trichomonas at 9%. The percent sensitivity versus control for Trichomonas ranged from 100% at time zero with and without reagent to 91% by 72 h. Gardnerella and Candida sensitivity remained at 100% for each time period. The Affirm VPIII ATTS system performed within 10% of the control swab (no transport reagent) at all four time points (0, 24, 48, and 72 h) for Trichomonas, Gardnerella, and Candida.
Attribute-Graph: A Graph Based Approach to Image Ranking (2015)

We propose a novel image representation, termed Attribute-Graph, to rank images by their semantic similarity to a given query image. An Attribute-Graph is an undirected fully connected graph, incorporating both local and global image characteristics. The graph nodes characterise objects as well as the overall scene context using mid-level semantic attributes, while the edges capture the object topology. We demonstrate the effectiveness of Attribute-Graphs by applying them to the problem of image ranking. We benchmark the performance of our algorithm on the 'rPascal' and 'rImageNet' datasets, which we have created in order to evaluate the ranking performance on complex queries containing multiple objects. Our experimental evaluation shows that modelling images as Attribute-Graphs results in improved ranking performance over existing techniques.
The Optimization Design of a Novel Slotted Microstrip Patch Antenna with Multi-Bands Using Adaptive Network-Based Fuzzy Inference System (2017)

This paper attempts to apply an adaptive network-based fuzzy inference system (ANFIS) for analysis of the resonant frequency of a single-layer single-patch microstrip rectangular patch antenna with two equal size slots which are placed on the patch in the form of parallel to resonance edges. The resonant frequency is calculated as the position of the slots is shifted from the right endpoint to the left endpoint on the patch between −4.2 mm ≤ Xslot ≤ 4.2 mm with the steps of 0.1 mm. The designed antenna is proposed for downlink of X band satellite, broadcasting satellite service, fixed-satellite service uplink, satellite (Earth-to-space), radio navigation, mobile-satellite (Earth-to-space), and KU band which can be achieved at the resonant frequencies of 7.2 GHz, 12.2 GHz, 14.6 GHz, 17.5 GHz and 19.3 GHz. Next, High Frequency Electromagnetic Field Simulation software (ANSYS HFSS) results for the prototype microstrip antenna are compared with the values obtained through ANFIS system. It can be concluded that the adaptive network-based fuzzy inference system in such designs can be conveniently used due to fuzzy system’s high approximation capability and much faster convergence rate. The best results for our ANFIS system can be obtained if Gaussian membership is used which leads to the mean absolute error of 1.4653.
Exenatide Sensitizes Insulin-Mediated Whole-Body Glucose Disposal and Promotes Uptake of Exogenous Glucose by the Liver (2008)

Exenatide directly stimulates glucose turnover by enhancing insulin-mediated whole-body glucose disposal and increasing hepatic uptake of exogenous glucose, contributing to its overall action to lower postprandial glucose excursions.
IgE‐mediated allergic reactions to fruit gums and investigation of cross‐reactivity between gelatine and modified gelatine‐containing products (1989)

A 32-year-old female reacted with a contact urticaria syndrome after eating 'gummy bears' (fruit gums). The reaction began in the oral mucosa and led to treatment on an inpatient basis. RAST measurements with allergen discs produced with gelatine and gelatine-containing products (among them 'gummy bears') demonstrated the presence of IgE antibodies in the serum of this patient. Proteins with molecular weights in the range of 40-120 kD were identified as the allergens in gelatine by using Western blot analysis. RAST inhibition showed cross-reactivity between gelatine, gelatine-containing products and the modified gelatine used in some plasma substitutes. Allergic reactions towards coloured fruit candies and 'gummy bears' may result from an IgE-mediated hypersensitivity towards gelatine. The long-known anaphylactoid reactions towards gelatine-containing plasma substitutes may, at least in part, be of an allergic nature.
Detection of Two New Variants of Soybean Kunitz Trypsin Inhibitor through Electrophoresis. (1996)

大豆の種子に含まれるKunitz型トリプシンインヒビター(SKTI)には電気泳動により識別される5種の多型(Tia,TibTic,欠失及び未命名)がある.TiaとTib型の間には8アミノ酸残基,TiaとTic型の間には1アミノ酸残基の違いがあることが知られているが,その中間が知られていない.本研究ではその中間型があるかどうかを知るため,電気泳動の移動度の僅かな違いが識別できるような電気泳動法を工夫し,日本の岩手県の62地点から採集した890ツルマメのサンプル(1991-1992年に採集)および173の日本及び中国の栽培品種を材料として(Tab1e1),Kunitz型トリプシンインヒビタータンパク質の電気泳動移動度の微小変異を示す多型性の有無について調査した.