gebhart/patrepeval huggingface dataset:
Simultaneous beam steering and null formation with coupled, nonlinear oscillator arrays (2005)

The ability of coupled, nonlinear oscillator arrays to produce simultaneous beam steering and null generation is presented. This technique, which extends the capabilities of such arrays to include interference suppression, is realized through a generalization of Steyskal's method of pattern nulling by phase perturbation. An illustrative example is provided.
Stationary Sequences and Random Fields (1985)

This book has a dual purpose. One of these is to present material which selec tively will be appropriate for a quarter or semester course in time series analysis and which will cover both the finite p
Sch 13521 In The Treatment Of Advanced Carcinoma Of The Prostate (1974)

No AccessJournal of Urology1 Jun 1974Sch 13521 In The Treatment Of Advanced Carcinoma Of The Prostate Bruce Stoliar, and David J. Albert Bruce StoliarBruce Stoliar More articles by this author , and David J. AlbertDavid J. Albert More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)60080-6AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail © 1974 by The American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetailsCited ByCrawford E, Schellhammer P, McLeod D, Moul J, Higano C, Shore N, Denis L, Iversen P, Eisenberger M and Labrie F (2018) Androgen Receptor Targeted Treatments of Prostate Cancer: 35 Years of Progress with AntiandrogensJournal of Urology, VOL. 200, NO. 5, (956-966), Online publication date: 1-Nov-2018.Decensi A, Boccardo F, Guarneri D, Positano N, Paoletti M, Costantini M, Martorana G and Giuliani L (2018) Monotherapy with Nilutamide, A Pure Nonsteroidal Antiandrogen, in Untreated Patients with Metastatic Carcinoma of the ProstateJournal of Urology, VOL. 146, NO. 2 Part 1, (377-381), Online publication date: 1-Aug-1991.Migliari R, Balzano S, Scarpa R, Campus G, Pintus C and Usai E (2018) Short Term Effects of Flutamide Administration on Hypothalamic-Pituitary-Testicular Axis in ManJournal of Urology, VOL. 139, NO. 3, (637-639), Online publication date: 1-Mar-1988.Sogani P and Whitmore W (2018) Experience with Flutamide in Previously Untreated Patients With Advanced Prostatic CancerJournal of Urology, VOL. 122, NO. 5, (640-643), Online publication date: 1-Nov-1979.Prout G, Irwin R, Kliman B, Daly J, Maclaughlin R and Griffin P (2018) Prostatic Cancer and Sch-13521: II. Histological Alterations and the Pituitary Gonadal AxisJournal of Urology, VOL. 113, NO. 6, (834-840), Online publication date: 1-Jun-1975.Caine M, Perlberg S and Gordon R (2018) The Treatment of Benign Prostatic Hypertrophy with Flutamide (SCH 13521): A Placebo-Controlled StudyJournal of Urology, VOL. 114, NO. 4, (564-568), Online publication date: 1-Oct-1975. Volume 111Issue 6June 1974Page: 803-807 Advertisement Copyright & Permissions© 1974 by The American Urological Association Education and Research, Inc.MetricsAuthor Information Bruce Stoliar More articles by this author David J. Albert More articles by this author Expand All Advertisement PDF DownloadLoading ...
American Indian Autobiography by H. David Bramble III (1990)

Reviews 255 Times. Libby Beaman may well have been ahead of her time in resisting 19th-century strictures on women; however, too much of this book reads as if it were written in the last year, not in the last century. TERRENCE COLE University of Alaska Fairbanks American Indian Autobiography. By H. David Bramble III. (Berkeley: Uni­ versity of California Press, 1988. 278 pages, $35.00.) This work presents an engaging, if troubling, argument about the evolu­ tion of Native American autobiography. Brumble begins with a key problem: is autobiography a Western genre? He believes that it is, and that it reflects a movement from tribal consciousness to self-consciousness—a progressive move­ ment. He examines early coup tales, and hunting and warfaring tales, and sees in them a lack of narrative connection, a lack of self-reflection, that one also finds in preliterate Greek and Egyptian societies. His central thesis is that the anthropologists’ forms of inquiry led the Indian interpreters who worked closely with them to evolve the first “true” Indian autobiographies because these Indians internalized the “why” format of Western thought, and devel­ oped a sense of self apart from tribally determined identity. For Brumble, Momaday’s Way to Rainy Mountain completes a cycle in which a now fully conscious, highly educated mixed-blood Kiowa man can transform the earlier narrative lapses and intense tribal consciousness into an artistic form. The hypothesis is interesting in its consideration of how knowing and expressing oneself change in relation to a dramatically different Other. What is naive in Brumble’s account isthe notion that oral forms are less sophisticated than literary ones, particularly in the context of performance, and that the movement towards autobiography is an evolution of “self” for Native Ameri­ cans. Just because the narrative connections we comprehend are not a part of an oral presentation does not mean that a person has no sense of self within community. Moreover, it could be said that those writing in an already estab­ lished literary form are less creative than those who, confronted by the new, struggle to express themselves in new ways. There is a surprising degree of ethnocentrism in American Indian Auto­ biography. There also is an assumption that the early male narrative forms are the forms, and that women’s stories are secondary. The attacks on fellow women scholars (Sands, Bataille, Underhill) are severe, and a major female writer is diminished as but an imitator of forms (Silko). The breadth of Brumble’s reading is impressive. His insights are far more narrow, highly judgmental, and misleading. ALANNA KATHLEEN BROWN Montana State University ...
A Heavy Duty Chlorine-Depolarized Cell (1948)

Chlorine can readily be activated electrochemically at carbon electrodes, these, in combination with conventional metal anodes, giving primary cells of high initial voltage (2.05–2.12 with zinc; 2.85–2.92 with magnesium) and good operating characteristics. Two chlorine‐depolarized reserve‐type cells are described, one of high capacity at moderate drain (6 amp. per sq. ft. [0.65 amp./dm.2]), the other designed for an exceedingly heavy discharge rate (75–150 amp. per sq. ft. [8–16 amp./dm.2]) for periods of only a few minutes.
Simulator X: A scalable and concurrent architecture for intelligent realtime interactive systems (2011)

This article presents a platform for software technology research in the area of intelligent Realtime Interactive Systems. Simulator X is targeted at Virtual Reality, Augmented Reality, Mixed Reality, and computer games. It provides a foundation and testbed for a variety of different application models. The current research architecture is based on the actor model to support fine grained concurrency and parallelism. Its design follows the minimize coupling and maximize cohesion software engineering principle. A distributed world state and execution scheme is combined with an object-centered world view based on an entity model. Entities conceptually aggregate properties internally represented by state variables. An asynchronous event mechanism allows intra- and interprocess communication between the simulation actors. An extensible world interface uses an ontology-based semantic annotation layer to provide a coherent world view of the resulting distributed world state and execution scheme to application developers. The world interface greatly simplifies configurability and the semantic layer provides a solid foundation for the integration of different Artificial Intelligence components. The current architecture is implemented in Scala using the Java virtual machine. This choice additionally fosters low-level scalability, portability, and reusability.
Durable Glass‐Ceramic Coatings for Foam Glass (2011)

This work describes the design and development of two new silica‐based glass‐ceramic coatings, suitable to be applied as slurries on a foam glass substrate. The coating process was optimized for both compositions, according to their sintering behavior. Scanning electron microscopy ( SEM ) observations and coefficient of thermal expansion ( CTE ) measurements revealed a good thermomechanical compatibility between the foam glass substrate and both coatings. The proposed coatings showed excellent chemical durability: no weight loss was observed after soaking in distilled water at 90°C for 16 days.
Microwave irradiation method for the synthesis of water-soluble CdSe nanoparticles with narrow photoluminescent emission in aqueous solution (2005)

Water-soluble CdSe nanoparticles with cubic phase and narrow photoluminescent emission have been synthesized in aqueous solution with the assistance of citric acid (CA) molecules by a microwave irradiation method. This synthesis process was so rapid that the CdSe nanoparticles were obtained within just a few minutes. The size and optical properties of the CdSe nanoparticles were well controlled by the CA molecules.
Antimalarial Activity of Multiple Dose and Single Dose Administration of Artocarpus Champeden Spreng. Stembark Extract on Plasmodium Berghei Infected Mice (2015)

Artocarpus champeden Spreng. (Moraceae) known as “cempedak”, was traditionally used for antimalarial remedies in Indonesia. Study to determine antimalarial activity of ethanol extract of cempedak stembark was carried out. Artocarpus champeden Ethanol Extract (ACEE) was administered twice per day (multiple dose) and once per day (single dose) orally. The study was carried out by modification method of the “4 Days Suppressive Test” originally described by Peter. The result showed that ACEE administered twice per day inhibited parasites growth (ED 0.19 mg/kg BW) higher than once per day (ED 6.0 mg/kg BW) and 10 mg/kg body weight of dose administrated twice per day was more effective than 100 mg/kg body weight once per day.
A Network Integration Approach for Drug-Target Interaction Prediction and Computational Drug Repositioning from Heterogeneous Information. (2017)

Abstract The emergence of large-scale genomic, chemical and pharmacological data provides new opportunities for drug discovery and repositioning. In this work, we develop a computational pipeline, called DTINet, to predict novel drug–target interactions from a constructed heterogeneous network, which integrates diverse drug-related information. DTINet focuses on learning a low-dimensional vector representation of features, which accurately explains the topological properties of individual nodes in the heterogeneous network, and then makes prediction based on these representations via a vector space projection scheme. DTINet achieves substantial performance improvement over other state-of-the-art methods for drug–target interaction prediction. Moreover, we experimentally validate the novel interactions between three drugs and the cyclooxygenase proteins predicted by DTINet, and demonstrate the new potential applications of these identified cyclooxygenase inhibitors in preventing inflammatory diseases. These results indicate that DTINet can provide a practically useful tool for integrating heterogeneous information to predict new drug–target interactions and repurpose existing drugs.
Epidermal growth factor receptor tyrosine kinase inhibitors (2004)

Activation of the epidermal growth factor receptor (EGFR) has been linked to tumour proliferation, invasion, metastasis and angiogenesis in epithelial tumours. Inhibitors of the EGFR have emerged as promising anticancer agents and two main approaches have been developed, humanised monoclonal antibodies and tyrosine kinase inhibitors. This review discusses the current status of EGFR tyrosine kinase inhibitors (EGFR-TKIs) that have entered clinical development. EGFR-TKIs are generally well tolerated and can sometimes produce impressive tumour regression in patients with advanced non-small-cell lung cancer. However, highly predictive or surrogate markers of activity have not been identified and there remains a need for translational research in their future development.
WALDIO: eliminating the filesystem journaling in resolving the journaling of journal anomaly (2015)

This work is dedicated to resolve the Journaling of Journal Anomaly in Android IO stack. We orchestrate SQLite and EXT4 filesystem so that SQLite's file-backed journaling activity can dispense with the expensive filesystem intervention, the journaling, without compromising the file integrity under unexpected filesystem failure. In storing the logs, we exploit the direct IO to suppress the filesystem interference. This work consists of three key ingredients: (i) Preallocation with Explicit Journaling, (ii) Header Embedding, and (iii) Group Synchronization. Preallocation with Explicit Journaling eliminates the filesystem journaling properly protecting the file meta-data against the unexpected system crash. We redesign the SQLite B-tree structure with Header Embedding to make it direct IO compatible and block IO friendly. With Group Synch, we minimize the synchronization overhead of direct IO and make the SQLite operation NAND Flash friendly. Combining the three technical ingredients, we develop a new journal mode in SQLite, the WALDIO. We implement it on the commercially available smartphone. WALDIO mode achieves 5.1× performance (insert/sec) against WAL mode which is the fastest journaling mode in SQLite. It yields 2.7× performance (inserts/ sec) against the LS-MVBT, the fastest SQLite journaling mode known to public. WALDIO mode achieves 7.4× performance (insert/sec) against WAL mode when it is relieved from the overhead of explicitly synchronizing individual log-commit operations. WALDIO mode reduces the IO volume to 1/6 compared against the WAL mode.
Evaluating I/O Scheduler in Virtual Machines for Mapreduce Application (2010)

This paper explores the relationship between I/O scheduling in a virtual machine monitor (VMM) and performance of Map Reduce applications running on the virtual machines (VMs). Traditionally, Map Reduce applications running on the virtual machines perform worse than on the physical machines due to competing for I/O. In this paper, we discuss the effect of I/O scheduling on performance of Map Reduce running on VMs. We present two strategies to improve the I/O scheduling and evaluate the performance through experiments. The results show that the strategies could reduce the percentage of I/O waiting and time consuming of Map Reduce applications effectively.
REPEATED TREATMENT WITH<i>S. AUREUS</i>SUPERANTIGENS EXPANDS THE SURVIVAL RATE OF EHRLICH ASCITES TUMOR BEARING MICE (2002)

The bacterial superantigen Staphylococcal enterotoxin-A (SEA), produced by some strains of Staphylococcus aureus, causes proliferation of cytotoxic T-lymphocytes and cytokine production in vivo. SEA has been shown to be highly efficient for antibody-targeted superantegen immunotherapy for different tumor models. A candidate B-cell superantigen that has received considerable attention these days is staphylococcal protein-A (PA). It has been shown to possess multiple immunological responses. The anti-tumor property of PA is well documented in the literature in various transplantable tumors of rats and mice. In the present study, we have shown that the T-cell superantigen SEA and B-cell superantigen PA induce immunomodulatory and anti-tumor activity which is strongly protentiated by PA + SEA co-administration. Combination treatment with PA and SEA prolongs the immune response in vivo, limits the development of immunological unresponsiveness and promotes maximum anti-tumor effects to tumor carrying animals, as compared with PA or SEA alone. The immune response after combined therapy is characterized by substantially augmented IFN-gamma, TNF-alpha, Nitric oxide and strong CTL activity. Our data demonstrate that combined PA + SEA therapy induces long-term survival of the animals, carrying the Ehrlich ascites tumor.
Effect of age on antibody responses after lung immunization. (1985)

The effects of age on the number of lymphoid cells producing specific IgM antibody (AFC) and the level of specific IgM, IgG, and IgA antibody after lung immunization were evaluated in groups of dogs 2 through 16 yr of age. A trend for lowered antibody responses in blood was observed with increasing age, and significantly lowered antibody responses were measured in lavage fluids from immunized lung lobes of older dogs. Statistical evaluations indicated that the lowered antibody responses in the lung were due in part to the reduced AFC and level of specific antibody in the blood. However, a less intense inflammatory response to antigen instilled into the lungs of older dogs also significantly contributed to the lowered antibody responses in their lungs. Additional studies are needed to determine if the loss of inflammation and antibody responses in the lungs of aged dogs increases their susceptibility to pulmonary infections.
Role of alveolar macrophage chemotaxis and phagocytosis in pulmonary clearance responses to inhaled particles: Comparisons among rodent species (1993)

Alveolar macrophages (AM) play an important role in clearing inhaled particles from the lung. The mechanisms through which macrophages identify particles that have been deposited in the alveolar regions is not well understood, although macrophage motility and phagocytic functions appear to be prerequisites for efficient clearance of inhaled materials. In previous studies, we assessed the mechanisms of macrophage-mediated clearance of inhaled particles using a rat model. In this regard, it appears that one mechanism by which rat alveolar macrophages are recruited to sites of particle or fiber deposition is through complement activation and consequent generation of chemotactic factors by the inhaled particulates. Whether this mechanism is operative in other rodent species remains an unanswered question. The current studies were undertaken to compare pulmonary clearance responses in several rodent species exposed to carbonyl iron (CI) particles. In vitro and in vivo pulmonary clearance responses were evaluated using one strain each of mouse, hamster, rat, and guinea pig. In vitro studies showed that hamster AM had the greatest phagocytic activity and that rat AM migrated best to complement-dependent chemotactic factors. Subsequently, groups of animals from each species were exposed to CI particles for 1 or 6 hr at aerosol concentrations of 100 mg/m3. Particle depositions patterns in the distal lung were nearly identical for all species, although enhanced numbers of CI particles were deposited on alveolar duct bifurcations of either rats or mice compared to hamsters, and particle deposition in guinea pigs was substantially lower. Time course studies showed that enhanced numbers of rat AM migrated to deposition sites and phagocytized particles, and this correlated with increased numbers and percentages of phagocytic macrophages recovered by lavage (P < 0.01). In vivo phagocytic rates were the lowest in the mouse, and this correlated with reduced phagocytic rates in vitro. It is concluded from these studies that the rat may be the most efficient rodent species in clearing inhaled iron particles. In addition, it is conceivable that hamster AM are recruited to sites of particle deposition by a noncomplement-mediated mechanism.
Use of an environment classification model (1993)

Various reference models have been proposed for the classification of features present in an integrated software engineering environment. Two such models are studied and a target system is mapped to the set of services present in these models. This system consisted of approximately 23000 lines of Pascal source code in 31 modules and provided tools for developing Pascal programs using either a syntax-directed editor or a line-oriented editor. In addition to describing the system, this mapping exercise provided additional feedback on the effectiveness of the two reference models used. The results of this mapping and comments on the effectiveness of the models are given. >
Joint optimization of number of clusterheads and spreading factor for network lifetime of low energy adaptive clustering hierarchy (2010)

Low energy adaptive clustering hierarchy (LEACH) is widely discussed, in the literature, for energy efficient data centric wireless sensor networks. Due to its seminal nature it has emerged as a benchmark for performance comparison. For uniform energy consumption of sensor nodes, it suggests rotation of the clusterhead role after a fixed duration, with probabilistic selection of sensor nodes as clusterheads for successive rounds. However, this probabilistic approach does not guarantee selection of equal number of nodes as clusterheads during different rounds. LEACH uses DS-SS to allow simultaneous data transmissions in different clusters. The variable number of clusterhead requires the spreading to be used to be more than that required with desired number of clusterheads. Enough amount of additional spreading is suggested to be used to avoid inter cluster interference. The optimum number of desired clusterhead is shown to be within 1 to 6% of total nodes. This makes it interesting to optimize the desired number of clusterheads and the spreading factor jointly for network lifetime, the most important performance metric used for evaluation, of LEACH. So, this paper presents the results of the optimization carried out through simulation, of LEACH, of different number of desired clusterheads and additional spreading required for its network lifetime.
Detecting Drivable Area for Self-driving Cars: An Unsupervised Approach (2017)

It has been well recognized that detecting drivable area is central to self-driving cars. Most of existing methods attempt to locate road surface by using lane line, thereby restricting to drivable area on which have a clear lane mark. This paper proposes an unsupervised approach for detecting drivable area utilizing both image data from a monocular camera and point cloud data from a 3D-LIDAR scanner. Our approach locates initial drivable areas based on a "direction ray map" obtained by image-LIDAR data fusion. Besides, a fusion of the feature level is also applied for more robust performance. Once the initial drivable areas are described by different features, the feature fusion problem is formulated as a Markov network and a belief propagation algorithm is developed to perform the model inference. Our approach is unsupervised and avoids common hypothesis, yet gets state-of-the-art results on ROAD-KITTI benchmark. Experiments show that our unsupervised approach is efficient and robust for detecting drivable area for self-driving cars.
Novel Integrin Antagonists Derived from Thrombospondins (2005)

Specific antagonists have been successfully developed for several different integrins. Clinical trials have been initiated to study therapeutic uses of these inhibitors in cancer, thrombosis, and inflammatory diseases. Most efforts to date have focused on the platelet integrin alphaIIbbeta3, endothelial alphavbeta3, and the leukocyte integrin alpha4beta1. However, the integrin family contains additional members with interesting tissue specificities and functional properties that could also be useful molecular targets for disease intervention. In many cases, specific recognition motifs for these integrins have not been identified, which has precluded development of specific antagonists. Our recent studies of thrombospondin-1 and thrombospondin-2 recognition by integrins have revealed novel motifs for alpha3beta1 and alpha6beta1 integrins as well as new motifs recognized by the well studied alpha4beta1 integrin. These three integrins play distinct roles in angiogenesis and its modulation by thrombospondins. This review will discuss recent insights into the specificities of alpha3beta1 and alpha6beta1 integrins, their functions in angiogenesis, and potential applications for antagonists of these integrins and of alpha4beta1 to control pathological angiogenesis and other diseases.