gebhart/patrepeval huggingface dataset:
Neurobehavioral phenotype observed in KBG syndrome caused by <i>ANKRD11</i> mutations (2012)

KBG syndrome is a rare disease characterized by typical facial dysmorphism, macrodontia of upper central incisors, skeletal abnormalities, and developmental delay. Recently, mutations in ANKRD11 gene have been identified in a subset of patients with KBG syndrome, while a contiguous gene deletion syndrome involving 16q24.3 region (including ANKRD11) was delineated in patients with facial dysmorphism, autism, intellectual disability, and brain abnormalities. Although numerous evidences point to a central causative role of ANKRD11 in the neurologic features of these patients, their neurocognitive and behavior phenotypes are still poorly characterized. Herein, we report the complete neurological and psychiatric features observed in two patients with KBG syndrome due to ANKRD11 mutations. Both patients show intellectual disabilities, severe impairment in communication skills, deficits in several aspects of executive functions and working memory and anxious traits. Their features are compared with those of previously reported patients with KBG syndrome aiding in the delineation of neurocognitive phenotype associated to ANKRD11 mutations.
Stimulation by Phagocytosis of the Deiodination of L-Thyroxine in Human Leukocytes (1972)

Intact human leukocytes actively deiodinate L-[(131)1] thyroxine, producing mainly inorganic (131)1 and chromatographically immobile (131)1-labeled origin material. When phagocytosis is induced, the deiodination is enhanced, a suggestion that deiodination in mediated by a peroxidase-hydrogen peroxide system. l-Thyroxine can serve as a source of iodine for iodination reactions within the leukocyte.
Enhanced challenge‐response set and secure usage scenarios for ordering‐based ring oscillator‐physical unclonable functions (2015)

The number of applicable challenge–response pairs (CRPs) in physical unclonable functions (PUFs) is critical especially for authentication protocols in security systems. Ideally, full read‐out of all CRPs should be infeasible and CRPs should be independent from each other for a highly secure system. CRP concept is not defined in ordering‐based ring oscillator (RO) PUFs presented in the literature. In this paper, the authors propose two methods for enhanced CRP set in ordering‐based RO‐PUFs and analyse their performance in terms of uniqueness and area efficiency. Next, they propose three secure usage scenarios based on enhanced CRP set methods, preventing the CRPs from leaking information about each other. With the proposed systems, 100% robust, area and power efficient and secure PUF structures with exponential number of CRPs become possible that are very convenient especially for authentication protocols.
Influence of Li-Ion Battery Models in the Sizing of Hybrid Storage Systems with Supercapacitors (2014)

This paper presents a comparative study of the influence of different aggregated electrical circuit battery models in the sizing process of a hybrid energy storage system (ESS), composed by Li-ion batteries and supercapacitors (SCs). The aim is to find the number of cells required to propel a certain vehicle over a predefined driving cycle. During this process, three battery models will be considered. The first consists in a linear static zeroeth order battery model over a restricted operating window. The second is a non-linear static model, while the third takes into account first- order dynamics of the battery. Simulation results demonstrate that the adoption of a more accurate battery model in the sizing of hybrid ESS's prevents over-sizing, leading to a reduction in the number of cells of up to 29%, and a cost decrease of up to 10%.
Improving the energy efficiency of conventional tumbler clothes drying systems (2001)

This paper discusses the drying processes of four different designs of household clothes tumbler dryer using electric power input. The relative advantages and disadvantages and the energy analyses of the dryers are presented. A parametric study was conducted to assess the effects of different variables on energy efficiency and specific moisture extraction rate. It is shown that the conventional tumbler dryer technology can be improved significantly by the use of heat-recovery heat exchangers. Copyright © 2001 John Wiley & Sons, Ltd.
Space-Charge Limit and Confinement in Particle Acceleration with High-Intensity Light Waves (1963)

Use of the strong electric fields from laser radiation to accelerate particles is complicated by many technical and theoretical problems. Effects of space charge in medium energy accelerators are examined, and the maximum current (proportional to the product of the wavelength and accelerating field) that can be accelerated using optical frequencies is calculated. The laser accelerator average current proves to be about 10-3 that of the microwave accelerator current, but the product of accelerator length and average current is about equal for the two types of accelerators. Due to the high field strength in optical accelerators, the equivalent d-c confinement force can be significant and may be used for particle beam confinement or for medium-energy beam acceleration. (auth)
Risk of Breast Cancer Among French-Canadian Women, Noncarriers of More Frequent<i>BRCA1/2</i>Mutations and Consumption of Total Energy, Coffee, and Alcohol (2009)

Although the connection between diet, lifestyle and hormones suggests that nutritional and lifestyle factors may exert an influence in the etiology of breast cancer, it is not clear whether these factors operate in the same way in women without BRCA gene mutations. A nested case-control study was conducted in a cohort of French-Canadian women, with 560 members involving 280 nongene carriers of mutated BRCA gene affected by breast cancer and 280 nonaffected and nongene carriers of mutated BRCA gene. A validated semi-quantitative food frequency questionnaire was used to ascertain dietary intake, and a core questionnaire, to gather information on lifestyle risk factors. Odds ratios (ORs) and 95% confidence intervals (CIs) were calculated in logistic regression models. It was found that energy intake >2,057 Kcal/day was significantly and positively related to breast cancer risk (OR = 2.54; 95% CI: 1.67-3.84; p = 0.01). Women who drank more than eight cups of coffee per day had an increased risk of breast cancer: OR = 1.40 (95% CI: 1.09-2.24; p = 0.03). Subjects who drank >9 g of alcohol (ethanol) per day had an increased risk of breast cancer: OR = 1.55 (95% CI: 1.02-2.37; p = 0.04). In addition, a positive and significant association was noted between the consumption of beer, wine and spirits, and breast cancer risk. The ORs were 1.34 (95% CI: 1.28-2.11; p = 0.04) for more than two bottles of beer per week, OR = 1.16 (95% CI: 1.08-2.58; p = 0.05) for >10 oz of wine per week and OR = 1.09 (95% CI: 1.02-2.08; p = 0.05) for >6 oz of spirit per week, respectively. Intakes of other nutrients and dietary components were not significantly associated with nongene carrier breast cancer risk. This study provides evidence that total energy intake, coffee, and alcohol consumption may play a role in breast cancer risk.
Cosine pattern synthesis for single and multiple main beam uniformly spaced linear arrays (1989)

The method of cosine pattern synthesis for single- and multiple-main-beam equispaced linear arrays is introduced. The cosine pattern function is characterized by the position of the main beam in the theta -domain and its half-power beamwidth. The Fourier series and Woodward-Lawson methods are applied to the special cases of single- or multiple-main-beam cosine pattern synthesis. The patterns produced by application of these classical shaped-beam synthesis methods can then be used as initial patterns for iterative and perturbational techniques. Examples are presented and discussed, including the use of multiple-main-beam cosine pattern synthesis to design a high-power, high-frequency, ground-based transmitter for the creation of an array of 'wireless' ionospheric dipoles.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
New Identity Management Scheme And Its Formal Analysis (2009)

As the Internet technology has developed rapidly, the number of identities (IDs) managed by each individual person has increased and various ID management technologies have been developed to assist users. However, most of these technologies are vulnerable to the existing hacking methods such as phishing attacks and key-logging. If the administrator-s password is exposed, an attacker can access the entire contents of the stolen user-s data files in other devices. To solve these problems, we propose here a new ID management scheme based on a Single Password Protocol. The paper presents the details of the new scheme as well as a formal analysis of the method using BAN Logic.
Improving Efficiency of a High Work Turbine Using Non-Axisymmetric Endwalls: Part II—Time-Resolved Flow Physics (2008)

This paper is the second part of a two part paper that reports on the improvement of efficiency of a one-and-half stage high work axial flow turbine. The first part covered the design of the endwall profiling as well as a comparison with steady probe data, this part covers the analysis of the time-resolved flow physics. The focus is on the time-resolved flow physics that lead to a total-to-total stage efficiency improvement of Δηtt = 1.0% ± 0.4%. The investigated geometry is a model of a high work (Δh/U2 = 2.36), axial shroudless HP turbine. The time-resolved measurements have been acquired upstream and downstream of the rotor using a Fast Response Aerodynamic Probe (FRAP). The paper contains a detailed analysis of the secondary flow field that is changed between the axisymmetric and the non-axisymmetric endwall profiling cases. The flowfield at exit of the first stator is improved considerably due to non-axisymmetric endwall profiling and results in reduced secondary flow and a reduction of loss at both hub and tip, as well as a reduced trailing shed vorticity. The rotor has reduced losses and a reduction of secondary flows mainly at the hub. At the rotor exit the flow field with non-axisymmetric endwalls is more homogenous due to the reduction of secondary flows in the two rows upstream of the measurement plane. This confirms that non-axisymmetric endwall profiling is an effective tool for reducing secondary losses in axial turbines. Using a frozen flow assumption the time-resolved data is used to estimate the axial velocity gradients, which are then used to evaluate the streamwise vorticity and dissipation. The non-axisymmetric endwall profiling of the first nozzle guide vane show reductions of dissipation and streamwise vorticity due to reduced trailing shed vorticity. This smaller vorticity explains the reduction of loss at mid-span, which is shown in the first part of the two part paper. This leads to the conclusion that non-axisymmetric endwall profiling also has the potential of reducing trailing shed vorticity.
Leed and Auger electron spectroscopy study of oxygen adsorption on tungsten /110/ (1971)

Previous studies indicate that gentian violet (GV), a triphenylmethane dye used in agriculture and human medicine, is a clastogen in vitro and a carcinogen in chronically exposed mice and rats. Data on its genotoxic activity, however, have been incomplete and partly contradictory. Mutagenesis and DNA damage experiments were conducted to re-evaluate the genotoxic potential of GV in both bacterial and mammalian cell systems. GV was mutagenic in Salmonella typhimurium tester strains TA97 and TA104, but there was little mutagenic activity detected in strains TA98 and TA100. A rat liver homogenate fraction (S9) tended to increase mutagenicity. The major microsomal metabolites of GV, pentamethylpararosaniline and N,N,N',N'-tetramethylpararosaniline were less mutagenic in TA97 and TA104, while N,N,N',N"-tetramethylpararosaniline was a weak mutagen in Salmonella. GV was not mutagenic in Chinese hamster ovary (CHO) cell strain CHO-K1-BH4, and was a questionable mutagen in CHO-AS52 cells. While GV produced DNA damage as measured by sedimentation of nucleotids derived from B6C3F1 mouse lymphocytes treated in vitro, no damage was found in lymphocytes isolated from mice dosed with GV. GV was also a weak producer of gene amplification in an SV40-transformed Chinese hamster cell line. The results indicate that GV is a point mutagen in bacteria; however, since similar exposure conditions produced weak mutagenic activity in mammalian cells, GV may be carcinogenic by virtue of its clastogenic activity.
Enhanced resistance of mice to Mycoplasma pulmonis-induced arthritis by administration of killed Corynebacterium parvum. (1981)

Inoculation of mice with Corynebacterium parvum 14 days before intraperitoneal inoculation of Mycoplasma pulmonis resulted in arthritis of significantly lesser magnitude than in control mice as measured both clinically and histologically. Mycoplasmas were isolated from the joints of mice inoculated with C. parvum less frequently than from control mice when the arthritis was maximal. Mycoplasmas were also isolated in smaller numbers from the blood and joints of mice pretreated with C. parvum within 2 hr after M. pulmonis inoculation. Complement-fixing antibody to M. pulmonis did not account for the differences observed. C. parvum given during an established mycoplasmal infection, although capable of enhancing elimination of M. pulmonis from the joints of infected mice, had no effect upon the arthritis as measured clinically or histologically. The results provide evidence that immunomodulators such as C. parvum are capable of enhancing elimination of mycoplasmas from the joints of infected mice prior to or after the induction of arthritis.
The instability of jets of arbitrary exit geometry (1995)

Abstract This paper describes a calculation technique to determine the linear instability characteristics of jets of arbitrary exit geometry. In particular, elliptic and rectangular jets are considered. The numerical procedure involves both a conformal transformation between the computational domain and the physical plane and a solution of the transformed stability equation in the computational domain. Modern, efficient, conformal mappings are used for both simply and doubly connected domains. The numerical solution is based on a hybrid finite difference/pseudospectral discretization of the stability equation. The technique is validated by comparison with previous stability calculations for circular and elliptic jets. Calculations are performed for the stability characteristics of elliptic and rectangular jets of aspect ratio 2:1. Growth rates, phase velocities, and pressure eigenfunctions are presented.
Spider web-inspired acoustic metamaterials (2016)

Spider silk is a remarkable example of bio-material with superior mechanical characteristics. Its multilevel structural organization of dragline and viscid silk leads to unusual and tunable properties, extensively studied from a quasi-static point of view. In this study, inspired by the Nephila spider orb web architecture, we propose a design for mechanical metamaterials based on its periodic repetition. We demonstrate that spider-web metamaterial structure plays an important role in the dynamic response and wave attenuation mechanisms. The capability of the resulting structure to inhibit elastic wave propagation in sub-wavelength frequency ranges is assessed, and parametric studies are performed to derive optimal configurations and constituent mechanical properties. The results show promise for the design of innovative lightweight structures for tunable vibration damping and impact protection, or the protection of large scale infrastructure such as suspended bridges.
Personalized Technology to Support Older Adults With and Without Cognitive Impairment Living at Home (2015)

Although persons with dementia (PWD) and their family caregivers need in-home support for common neuropsychiatric symptoms (NPS), few if any assistive technologies are available to help manage NPS. This implementation study tested the feasibility and adoption of a touch screen technology, the Companion, which delivers psychosocial, nondrug interventions to PWD in their home to address individual NPS and needs. Interventions were personalized and delivered in home for a minimum of 3 weeks. Postintervention measures indicated the technology was easy to use, significantly facilitated meaningful and positive engagement, and simplified caregivers' daily lives. Although intervention goals were met, caregivers had high expectations of their loved one's ability to regain independence. Care recipients used the system independently but were limited by cognitive and physical impairments. We conclude the Companion can help manage NPS and offer caregiver respite at home. These data provide important guidance for design and deployment of care technology for the home.
ChemInform Abstract: CONTRIBUTION OF LIPOPHYLICITY TO THE PERFORMANCE OF CROWN ETHERS. EFFECT OF BULK AND SHAPE OF THE LIPOPHYLIC SUBSTITUENTS (1983)

Abstract Octylbromid wird in Gegenwart von substituierten Kronenethern in Octyliodid umgewandelt.
Enhanced Epithelial-to-Mesenchymal Transition Associated with Lysosome Dysfunction in Podocytes: Role of p62/Sequestosome 1 as a Signaling Hub (2015)

The lack of phosphorylated p62 leads to a faster exit from cell mitosis, enhanced EMT associated with lysosome dysfunction may be attributed to accumulation of p62 and associated reduction of p62 phosphorylation.
Elf: computer automation and error correction for a microwave network analyzer (1988)

A microwave measurement system has been developed that combines a personal computer (PC) and an conventional vector network analyzer to yield a full complex-error-corrected automatic network analyzer. The system consists of a Hewlett-Packard HP 8410C network analyzer, an HP 8350B sweep oscillator, and an IBM PC. A program called Elf runs on the PC, performing calibration and measurement algorithms and providing a flexible, menu-oriented user interface. The system, when calibrated, achieves a worst-case measurement error vector of magnitude <or=0.02 for transmission and reflection coefficient measurements over the 2-12.4-GHz frequency range and has a measurement speed of three frequency points/s. Elf provides an inexpensive method for upgrading the HP 8410 to achieve the high accuracy of an automatic network analyzer.<<ETX>>
Magnetic order of FeCl3 and CoCl2 intercalated graphite (1984)

We have investigated by neutron diffraction the magnetic properties of first- and second-stage FeCl3 and CoCl2 graphite intercalation compounds. They can be considered as quasi-two-dimensional magnetic systems in which one can vary both the 3D magnetic coupling and the intralayer magnetic interactions. The FeCl3 compounds are Heisenberg systems in which we have found that strong 2D magnetic correlations develop below 40 K; in the first-stage compound, the 3D coupling is strong enough to allow a transition to a 3D order below 3.8 K. The in-plane order is always an incommensurate modulation. In the CoCl2 compounds we have observed on the contrary an antiferromagnetism along c axis with the moments in the layer plane. They are 2D X-Y systems with a Kosterlitz–Thouless transition in which however the 3D coupling plays an important role.
Human Papillomavirus Infection in HIV-1 Infected Women in Catalonia (Spain): Implications for Prevention of Cervical Cancer (2012)

The high prevalence of HPV infection and cervical lesions in the HIV-1-infected population in Catalonia, as well as the low coverage and frequency of screening in this group, means that better preventive efforts are necessary and should include vaccination against HPV, better accessibility to screening programs, training of health care professionals, and specific health education for HIV-1-infected women.
Synthesis of a Carbon Analogue of <i>N</i>-Acetylmannosamine via Acetolysis on a Relatively Stable Ozonide (2002)

After a 2-methylpropenyl group was added to a carbohydrate framework through regioselective opening of a glucose-derived epoxide, hydrolysis or acetolysis of the methyl glycoside in various derivatives was problematic. Ozonolysis of the olefin followed by brief treatment with dimethyl sulfide gave a mixture of diastereomeric ozonides that proved to be stable for weeks at room temperature. Acetolysis of these ozonides at low temperature allowed selective cleavage of the methyl glycoside in the presence of the 1,2,4-trioxolane as well as selective formation of the alpha-acetate.
Performance, Emissions and Exhaust-Gas Reforming of an Emulsified Fuel: A Comparative Study with Conventional Diesel Fuel (2009)

<div class="htmlview paragraph">The fuel reforming technology has been extensively investigated as a way to produce hydrogen on-board a vehicle that can be utilized in internal combustion engines, fuel cells and aftertreatment technologies. Maximization of H<sub>2</sub> production in the reforming process can be achieved when there is optimized water (steam) addition for the different reforming temperatures. A way to increase the already available water quantity on-board a vehicle (i.e. exhaust gas water content) is by using emulsified fuel (e.g. water-diesel blend). This study presents the effect of an emulsified diesel fuel (a blend of water and diesel fuel with an organic surfactant to make the mixture stable) on combustion in conjunction with exhaust gas assisted fuel reforming on a compression ignition engine. No engine modification was required to carry out these tests. The emulsified diesel fuel consisted of about 80% (mass basis) of conventional ultra low sulphur diesel (ULSD) fuel and fixed water content. Results are compared to those obtained with ULSD fuel based on a) engine performance, b) engine emissions, c) hydrogen production, and d) efficiency of the reforming process. A smoke reduction of about 30–55% throughout all the testing conditions was achieved with the emulsified fuel while the NOx emissions reduction was in the range of 10–50%. As expected, fuel consumption was increased, due to the reduced calorific value of the emulsified fuel, but no negative effect on the brake thermal efficiency was observed. In the fuel reforming process, hydrogen production showed a strong dependence on the steam-to-fuel (S/F) ratio.</div>
A Hemispherical Sparse Phased Array Design For Low Frequency Transcranial Focused Ultrasound Applications Without Skull-Specific Phase Aberration Correction (2006)

A sparse large‐element hemispherical phased array scheme was investigated for low frequency transcranial focused ultrasound applications without skull‐specific phase aberration correction. The simulated transcranial focused beams in brain from the randomly distributed sparse array elements (0.25 MHz, 125 mm radius of curvature, 250 mm diameter, 50% sparsity of 953 square elements of 10 mm spacing) could be steered without skull specific aberration correction at 0.25 MHz. The 28 foci were on average 1.7±1.2 mm shifted from their intended locations. The average −3 dB beam width and length were 3.3±1.2 mm and 6.3±2.2 mm, respectively. The sidelobe levels ranged from 28% to 62% of the peak pressure values. The focal beam was steerable 35 mm laterally away from the transducer center axis and 30 mm axially in the transducer center axis when the sidelobe pressure values were 50% of or less than the peak pressure values. This allows the array to be mechanically aimed to one quarter of the brain and then electronically steered. The sparse array design offers a tradeoff between the best beam steering range and the manageable number of elements for a practical clinical system.