gebhart/patrepeval huggingface dataset:
Transient expression of [D-Ala2] deltorphin I-like immunoreactivity in prenatal rat small intestine. (1994)

We studied the distribution of immunoreactive elements for [D-Ala2] deltorphin I (DADTI), a delta-opioid receptor ligand, in fetal and postnatal rat small intestine. DADTI-like immunoreactive cells were detected transiently on embryonic Days 20 and 21. Electron microscopic examination revealed that positive staining occurred in mucous epithelial cells, either mature goblet cells or undifferentiated cells containing only a few mucous granules. Positive immunoreaction products in mature goblet cells were confined in their apical cytoplasm to the luminal parts of mucous granule aggregates. The result suggests that a DADTI-like molecule(s) is synthesized in rat intestinal goblet cells and is secreted in a diacrine fashion into the intestinal lumen at a late fetal period. The molecule(s) thus secreted may be important for the intestine of rats just before birth, because DADTI-like immunopositive goblet cells are no longer seen at any postnatal period.
EVALUATION OF POLYMERS FOR IMPROVING CEMENT MORTARS --THE PRODUCTION, PERFORMANCE AND POTENTIAL OF POLYMERS IN CONCRETE. 5TH INTERNATIONAL CONGRESS ON POLYMERS, BRIGHTON, SEPTEMBER 24-27, 1987 (1988)

A repair programm starts with an evaluation of the damage, and progresses through selection of materials and methods, preparation of the deficient area, and application of the repair. If each of these steps is done correctly at the proper time, then a satisfactory repair will be obtained. Acrylic modified cement mortars combats successfully the short-comings of non modified mortars. There is no question that there is a very positive need for epoxides but very often the high quality is not required, or repairs with epoxide based products rupture due to the dissimilar coefficient of thermal expansion. Acrylic modified cement mortars bridge the cement-epoxy gap in performance and price and are excellent products for use in new constructions as well as in repair work.(a) for the covering abstract of this congress see IRRD 814075.
Materials reliability, 1999 programs and accomplishments (2000)

The Materials Reliability Division develops measurement technologies that enable the producers and users of materials to improve the quality and reliability of their products. Measurement technologies, and the associated materials science base, are developed for materials evaluation to assure reliable performance, for nondestructive evaluation to assure quality of finished materials and products, and for process control to improve the quality and consistency of materials.
Towards sustainable polymer chemistry with homogeneous metal-based catalysts (2013)

A qualitative approach to maximizing sustainability in polymer chemistry.
Novel Risk Scoring System With Preoperative Objective Parameters Gives a Good Prediction of 1-Year Mortality in Patients With a Left Ventricular Assist Device (2012)

The TVAD score can predict the prognosis after LVAD implantation much better than the previously known methods.
Mind the Gap: On the Relationship Between Automatically Measured and\n Self-Reported Productivity (2020)

To improve software developers' productivity has been the holy grail of\nsoftware engineering research. But before we can claim to have improved it, we\nmust first be able to measure productivity. This is far from trivial. In fact,\ntwo separate research lines on software engineers' productivity have co-existed\nalmost in complete isolation for a long time: automated product and process\nmeasures on the one hand and self-reported or perceived productivity on the\nother hand. In this article, we bridge the gap between the two with an\nempirical study of 81 software developers at Microsoft.\n
Regulation of the growth and development of sympathetic neurons in vivo. (1977)

The superior cervical ganglion (SCG) in the neonatal mouse and rat has been employed as a model system to study the regulation of ontogeny of presynaptic cholinergic nerves and postsynaptic adrenergic neurons. During postnatal development presynaptic choline acetyltransferase (ChAc) activity increases 30- to 40-fold, whereas postsynaptic tyrosine hydroxylase (T-OH) activity rises 6- to 8-fold. Transection of the presynaptic cholinergic nerves innervating the SCG prevents the normal development of T-OH activity and the normal accumulation of T-OH enzyme molecules in each postsynaptic neuron. The trans-synaptic regulation of T-OH development is apparently mediated by acetylcholine and postsynaptic depolarization, since pharmacologic ganglionic blockade also prevents normal maturation. Ganglion decentralization also prevents the normal maturation of adrenergic nerve terminals, and the development of end-organ innervation by SCG. Consequently, trans-synaptic factors regulate the ontogeny of adrenergic terminals as well as perikarya. Moreover, normal efferent as well as afferent connections are apparently required for sympathetic development, since removal of salivary glands and orbital contents, target organs of the SCG, in neonates also prevents T-OH development in the ganglia. The postsynaptic neuron contributes to the development of presynaptic cholinergic fibers in SCG. Selective destruction of adrenergic neurons in neonatal mice with either 6-hydroxydopamine or antiserum to nerve growth factor prevents the normal maturation of ChAc activity in presynaptic terminals of SCG. Thus, presynaptic and postsynaptic cells appear to exert reciprocal regulatory influences during ontogeny.
Driver classification and driving style recognition using inertial sensors (2013)

Currently there are many research focused on using smartphone as a data collection device. Many have shown its sensors ability to replace a lab test bed. These inertial sensors can be used to segment and classify driving events fairly accurately. In this research we explore the possibility of using the vehicle's inertial sensors from the CAN bus to build a profile of the driver to ultimately provide proper feedback to reduce the number of dangerous car maneuver. Braking and turning events are better at characterizing an individual compared to acceleration events. Histogramming the time-series values of the sensor data does not help performance. Furthermore, combining turning and braking events helps better differentiate between two similar drivers when using supervised learning techniques compared to separate events alone, albeit with anemic performance.
CAPSULAR POLYSACCHARIDES OF SERRATIA MARCESCENS (1965)

Four polysaccharides were isolated from the capsular layer of Serratia marcescens cells grown on a sucrose medium. In composition, electrophoretic behavior, and sedimentation in the ultracentrifuge, all were shown to be markedly different. Analytical data indicated that the polysaccharides were an acidic glucomannan (I), a rhamnoglucan (II), a glucoheptan (III), and a rhamnoheptoglucan (IV). In I, in addition to the main acidic component D-glucuronic acid, a small amount of guluronic acid was also identified. A relatively high protein or peptide content in the purified polysaccharides suggested that it was firmly bound to the carbohydrate structure; "bound" lipid consisting mainly of hydroxymyristic acid was also a part of the structure. Methylation studies established the main glycosidic linkages in I, II, and III. The capsular polysaccharides had properties similar to those of polysaccharides isolated from a culture filtrate of S. marcescens in an earlier study, and a possible relationship between these two groups of polysaccharides is discussed.
Development of a reliable and easy method for screening oenococcus carbohydrate consumption profile (2010)

International audience
<i>N</i>-Benzylbutanamides as New Potential Herbicides (1981)

Journal Article N-Benzylbutanamides as New Potential Herbicides Get access Osamu Kirino, Osamu Kirino Research Department, Pesticides Division, Sumitomo Chemical Co., Ltd., 4–2–1, Takatsukasa, Takarazuka, Hyogo 665, Japan Search for other works by this author on: Oxford Academic Google Scholar Kunihiko Furuzawa, Kunihiko Furuzawa Research Department, Pesticides Division, Sumitomo Chemical Co., Ltd., 4–2–1, Takatsukasa, Takarazuka, Hyogo 665, Japan Search for other works by this author on: Oxford Academic Google Scholar Hiroshi Matsumoto, Hiroshi Matsumoto Research Department, Pesticides Division, Sumitomo Chemical Co., Ltd., 4–2–1, Takatsukasa, Takarazuka, Hyogo 665, Japan Search for other works by this author on: Oxford Academic Google Scholar Naganori Hino, Naganori Hino Research Department, Pesticides Division, Sumitomo Chemical Co., Ltd., 4–2–1, Takatsukasa, Takarazuka, Hyogo 665, Japan Search for other works by this author on: Oxford Academic Google Scholar Akihiko Mine Akihiko Mine Research Department, Pesticides Division, Sumitomo Chemical Co., Ltd., 4–2–1, Takatsukasa, Takarazuka, Hyogo 665, Japan Search for other works by this author on: Oxford Academic Google Scholar Agricultural and Biological Chemistry, Volume 45, Issue 11, 1 November 1981, Pages 2669–2670, https://doi.org/10.1080/00021369.1981.10864948 Published: 01 November 1981 Article history Received: 26 August 1981 Published: 01 November 1981
Liquid chromatography/tandem mass spectrometry method for the simultaneous determination of olanzapine, risperidone, 9‐hydroxyrisperidone, clozapine, haloperidol and ziprasidone in rat plasma (2007)

A simple, sensitive and rapid liquid chromatography/electrospray ionization tandem mass spectrometry (LC/ESI-MS/MS) method was developed and validated for simultaneous quantification of olanzapine, clozapine, ziprasidone, haloperidol, risperidone, and its active metabolite 9-hydroxyrisperidone, in rat plasma using midazolam as internal standard (IS). The analytes were extracted from rat plasma using a single step liquid-liquid extraction technique. The compounds were separated on a Waters Atlantis dC-18 (30 mm x 2.1 mm i.d., 3 microm) column using a mobile phase of acetonitrile/5 mM ammonium formate (pH 6.1 adjusted with formic acid) with gradient elution. All of the analytes were detected in positive ion mode using multiple reaction monitoring (MRM). The method was validated and the specificity, linearity, lower limit of quantitation (LLOQ), precision, accuracy, recoveries and stability were determined. LLOQ was 0.1 ng/mL and correlation coefficient (R(2)) values for the linear range of 0.1-100 ng/mL were 0.997 or greater for all the analytes. The intra-day and inter-day precision and accuracy were better than 8.05%. The relative and absolute recovery was above 77% and matrix effects were low for all the analytes except for ziprasidone. This validated method has been successfully used to quantify the plasma concentration of the analytes after chronic treatment with antipsychotic drugs.
Four-wave-mixing based silicon integrated optical isolator with dynamic non-reciprocity (2017)

A silicon integrated optical isolator with dynamic non-reciprocity based on the four-wave-mixing nonlinear effect is proposed and experimentally demonstrated. Measurement results show that >17 dB isolation ratio and <12 dB insertion loss can be achieved.
Idaho National Engineering Laboratory In Situ Vitrification Project FY-91 progress report (1992)

The purpose of this report is to present an overview conducted under the In Situ Vitrification (ISV) Project at the Idaho National Engineering Laboratory (INEL) during the 1991 Fiscal Year. The report will concentrate on describing the activities being conducted by the ISV project at the INEL and the advances made in this project at the INEL and the advances made in this project during FY 1991. Because detailed descriptions of the ISV process are available elsewhere (Arrenholz et al. 1990, Callow et al. 1991a), this discussion will not be repeated here.
Monitoring minimal residual disease and controlling drug resistance in chronic myeloid leukaemia patients in treatment with imatinib as a guide to clinical management (2006)

Imatinib mesylate, binding to the inactive conformation of Bcr-Abl tyrosine kinase and suppressing the Ph chromosome positive clone, has revolutionized the treatment of chronic myeloid leukaemia (CML) patients. Given the high rates of clinical and cytogenetic remission achieved, the molecular monitoring of BCR-ABL transcript levels by RT-qPCR has become always more important to assess minimal residual disease. Recently, recommendations for harmonizing current methodologies for detecting and measuring BCR-ABL transcripts in CML patients have been suggested. Studies of imatinib-treated patients have determined that the BCR-ABL levels measured early in therapy may predict durable cytogenetic remission and in turn prolonged progression free-survival or acquisition of resistance. The major mechanism of imatinib resistance is clonal expansion of leukaemia cells with mutations in the Bcr-Abl fusion tyrosine kinase. The early reduction of such mutations may allow timely treatment intervention to prevent or overcome resistance. We review current trends in the management of chronic myeloid leukaemia patients undergoing treatment with tyrosine kinase inhibitors.
A Disruptive Receiver Architecture Dedicated to Software-Defined Radio (2008)

The next generation of mobile terminals is faced with the emergence of the software-defined radio (SDR) concept. The communication devices tend to provide various wireless services through a multi-functional, multi-mode and multi-standard terminal. The SDR concept aims at designing a re-configurable radio architecture accepting all cellular or noncellular standards working in the 0-5-GHz frequency range. Some technical challenges have to be solved in order to address this concept. Working in the digital domain may be a solution but the analog-to-digital conversion cannot be done at Radio Frequencies, at an acceptable resolution and at an acceptable level of power consumption. The idea proposed here was to interface an analog pre-processing circuit between the antenna and a digital signal processor to pre-condition the RF signal. It uses the principle of a fast Fourier transform to carry out basic functions with high accuracy in a low-cost technology like CMOS. This paper presents the design and the behavioral simulations of this analog discrete-time device which gives the hardware flexibility required for a cognitive radio component.
Solvating Insoluble Carbon Nanostructures by Molecular Dynamics (2013)

A full understanding of the mechanisms that lead to the dispersion of carbon nanotubes (CNTs) is still lacking. Computer simulations are a convenient tool to study the solvation of CNTs because they can give a microscopic picture of the process. Molecular dynamics simulation describes in detail the interface and morphology of molecules adsorbed on carbon surfaces and, more importantly, the interaction mechanisms that take place in different supramolecular aggregates such as in water, organic solvents and ionic liquid. Understanding the self-assembly mechanisms will guide further improvement of carbon nanostructure dispersion, sorting, and separation and facilitate the design of novel carbon-based nanomaterials. The most common method to separate nanotubes from their bundles is liquid phase exfoliation and stabilization of nanotubes. Such stabilization cannot occur unless the attractive inter-nanotube potential is balanced by a repulsive potential. Two main stabilization techniques include electrostatic stabilization and steric stabilization.
Eight-channel wavelength multiplexing with 200-GHz spacing using uncooled coaxial fiber Bragg grating external-cavity semiconductor laser module (2002)

As a low-cost light source for wavelength-division-multiplexing networks, the authors develop an uncooled coaxial fiber Bragg grating external-cavity semiconductor laser (FGL). To realize high-wavelength stability, an FGL structure is adopted, and to reduce the cost of light source itself, a coaxial pigtail module structure is selected. High-wavelength stabilities of 2 pm/mA and 12 pm/K against current and ambient temperature variation are realized. Using the FGLs, successive eight-channel wavelength multiplexing with 200-GHz spacing and with almost the same peak power is realized between -30/spl deg/C to 70/spl deg/C. For each channel, the wavelength difference from the corresponding ITU grid is only within /spl plusmn/0.1 nm at 25/spl deg/C.
On overfitting, generalization, and randomly expanded training sets (2000)

An algorithmic procedure is developed for the random expansion of a given training set to combat overfitting and improve the generalization ability of backpropagation trained multilayer perceptrons (MLPs). The training set is K-means clustered and locally most entropic colored Gaussian joint input-output probability density function (pdf) estimates are formed per cluster. The number of clusters is chosen such that the resulting overall colored Gaussian mixture exhibits minimum differential entropy upon global cross-validated shaping. Numerical studies on real data and synthetic data examples drawn from the literature illustrate and support these theoretical developments.
On a Marine Caddis-fly (Philanisus, Walker,=Anomalostoma, Brauer) from New Zealand. (1882)

On a Marine Caddis-fly (Philanisus, Walker,=Anomalostoma, Brauer) from New Zealand. Get access R. McLachlan, F.R.S., F.L.S. R. McLachlan, F.R.S., F.L.S. 1Hon. Memb. N.-Z. Institute. Search for other works by this author on: Oxford Academic Google Scholar Zoological Journal of the Linnean Society, Volume 16, Issue 94, July 1882, Pages 417–422, https://doi.org/10.1111/j.1096-3642.1882.tb02386.x Published: 23 December 2008
Electrooptic narrow linewidth wavelength tuning and intensity modulation of an erbium fiber ring laser (1996)

International audience
Frequency Comb Velocity Modulation Spectroscopy (2011)

Author Institution: JILA, National Institute of Standards and Technology and University of Colorado; Department of Physics, University of Colorado, Boulder, Colorado 80309-0440, USA
“Jack” (1940)

Journal Article “Jack” Get access Richard Hussey Richard Hussey Search for other works by this author on: Oxford Academic Google Scholar Notes and Queries, Volume 179, Issue 3, 20 July 1940, Page 51, https://doi.org/10.1093/nq/179.3.51a Published: 20 July 1940
Intramolecular reactions. Part VII. Cyclisation of aryl 3-chloropropyl sulphones (1968)

Aryl 3-chloropropyl sulphones react with potassium t-butoxide in t-butyl alcohol to give aryl cyclopropyl sulphones in high yields. The effects of substituents in the aromatic nucleus upon the rate of the reaction have been determined, and a rectilinear Hammett plot with ρ=+2·32 is obtained. Hydrogen atoms of the methylene group adjacent to the sulphonyl group are rapidly exchanged under basic conditions in deuteriated solvents, and the rate of cyclisation of 3-chloro-1,1-dideuteriopropyl p-tolyl sulphone in t-butyl [2H] alcohol is twice that of the isotopically normal sulphone in t-butyl [1H]alcohol. These results suggest that an intermediate carbanion is formed and that the ρ-value obtained for the reaction is a composite one which incorporates opposing effects upon the equilibrium concentration of the carbanion and its nucleophilicity in the subsequent ring-closure step. This finding is briefly discussed in relation to current views on cyclisation.
Stacking Sequence Optimizations of Composite Structures Using Fractal Branch and Bound Method. Optimization Problem Includes In-Plane and Out-of-Plane Lamination Parameters. (2003)

In the present study, a mechanism of fractal image of laminates on lamination parameters is discussed in detail, and a stacking sequence optimization method using the mechanism is proposed for complicated structures that include both of in-plane and out-of-plane lamination parameters. The new method employs branch and bound method for the optimizations of stacking sequences. For the estimation of the fractal branch of stacking sequences, the new method requires approximation of the objective function of the optimizations with quadratic polynomials using both in-plane and out-of-plane lamination parameters. The new method is applied to a stacking sequence optimization problem of a maximization of buckling load of a hat type stringer structure. The method gives successfully optimal stacking sequences in a short time.
Evaluation of Ultrafast CT Scanning of the Adult Abdomen (1989)

Various measures of image quality were compared from adult abdomen scans obtained with a subsecond computed tomographic (CT) scanner (Imatron Ultrafast C-100) and a conventional third-generation whole-body scanner (GE9800). Forty images from 13 patients scanned within 2 hours of each other on both scanners were evaluated with techniques standardized as much as possible for CT exposure factors and contrast enhancement. Two observers in consensus evaluated matched anatomic levels using standard window width and level settings. Each image was graded on a scale of 1 (worst) to 5 (best) for spatial resolution, image noise, and presence and type of artifacts. Overall image quality also was graded. Averaged scores were compared between the two scanners. In all categories, scores were slightly higher for the GE9800. However, the differences in spatial resolution, presence of artifacts, overall image quality were not significant using the sign test. There was a significant difference, in favor of the GE9800, in image noise. The types of artifacts differed; the GE9800 produced more motion artifacts from bowel and surgical clips and the Imatron C-100 produced more rib shadow artifacts projecting on the liver and spleen. While the GE9800 produced abdominal images of slightly superior quality in adults, the Imatron Ultrafast C-100 was shown to produce images suitable for routine abdominal imaging in adults.
A study of the short‐time variation and interrelationship of plasma hormone levels reflecting pituitary, adrenocortical and testicular function in fertile men (1981)

Using radioimmunoassay method, we have estimated the levels of cortisol (C), pregnenolone (delta 5P), 17-hydroxypregnenolone (17-OH-delta 5P), dehydroepiandrosterone (DHEA), 17-hydroxyprogesterone (17-OH-P), androstenedione (A), testosterone (T) and dihydrotestosterone (DHT) in peripheral plasma samples collected at short-time (15 min) intervals from 10 fertile men, during two 4-h periods (06.00 to 10.00 and 18.00 to 22.00). In addition, the levels of biologically active luteinizing hormone (LH) were measured by an in vitro bioassay method in 9 of the subjects. The levels of all steroids studied exhibited diurnal variation with higher levels during the morning and lower levels during the evening period. The cortisol and the delta 5-steroid levels also exhibited individual short-term episodic spikes during the 2 periods. No short-term variation was observed in the levels of 17-OH-P, A, T and DHT. Statistically significant correlations were found between the levels of C and those of the delta 5-steroids and A in most of the subjects. No correlation was found between the above steroid levels and those of 17-OH-P, T and DHT. Also the LH levels exhibited episodic spikes of 60 to 90 min duration, but no diurnal variation. When the LH levels were related to those of T found in the same samples or in samples withdrawn 15 to 810 min afterwards, a significant positive correlation was found on repeated occasions in 5 of the 9 subjects. No systematic negative correlation was found when the T levels were related to those of LH in the same sequential fashion. Whereas the positive correlations found between LH and T levels in some of the subjects might suggest that physiological changes in peripheral LH levels are instrumental in regulating T-secretion, the rather consistent lack of significant negative correlation between T and LH levels seems to favour the view that the release of LH is not modulated by peripheral testosterone levels alone.