gebhart/patrepeval huggingface dataset:
Formation and Dielectric Properties of Glass in the System As-Te (1965)

The regions of glass formation in the system As-Te, d.c. conduction and dielectric properties of glass obtained are investigated. Glasses are formed only by quenching. Measurements of the dielectric constant over 60 c/s to 3 Mc/s on glass show two sorts of separable dispersions. It is ascertained that one is due to the surface effect and the other due to the bulk effect. Activation energy derived from the temperature dependence of dielectric relaxation time in the latter, which is present at the higher frequencies, and that of d.c. conductivity are found to be equal. Moreover, ε0, dielectric constant at f→0 when only the relaxation phenomenon at the higher frequencies is taken into account, is considerably high and seems to be almost temperature independent. These facts suggest that the dispersion at the higher frequencies is caused by inhomogeneous structure in bulk.
[Delayed diagnosis or misdiagnosis of pulmonary tuberculosis: 458 cases clinical analysis]. (2004)

The reasons for delayed diagnosis or misdiagnosis are as follows: A careless attitude towards health condition by patients themselves; neglected bacteriological evidence or ignorance of tuberculosis by physicians.
Innovative Enzymatic Approach to Resolve Homogalacturonans Based on their Methylesterification Pattern (2012)

Three series of model homogalacturonans (HGs) covering a large range of degree of methylesterification (DM) were prepared by chemical and/or enzymatic means. Randomly demethylesterified HGs, HGs containing a few long demethylesterified galacturonic acid stretches, and HGs with numerous but short demethylesterified blocks were recovered. The analysis of the degradation products generated by the action of a purified pectin lyase allowed the definition of two new parameters, the degree of blockiness, and the absolute degree of blockiness of the highly methylesterified stretches (DBMe and DB(abs)Me, respectively). By combining this information with that obtained by the more traditional endopolygalacturonase digestion, the total proportion of degradable zones for a given DM was measured and was shown to permit a clear differentiation of the three types of HG series over a large range of DM. This double enzymatic approach will be of interest to discriminate industrial pectin samples exhibiting different functionalities and to evaluate pectin fine structure dynamics in vivo in the plant cell wall, where pectin plays a key mechanical role.
The 3D virtual environment online for real shopping (2015)

The development of information technology and Internet has led to rapidly progressed in e-commerce and online shopping, due to the convenience that they provide consumers. E-commerce and online shopping are still not able to fully replace onsite shopping. In contrast, conventional online shopping websites often cannot provide enough information about a product for the customer to make an informed decision before checkout. 3D virtual shopping environment show great potential for enhancing e-commerce systems and provide customers information about a product and real shopping environment. This paper presents a new type of e-commerce system, which obviously brings virtual environment online with an active 3D model that allows consumers to access products into real physical environments for user interaction. Such system with easy process can helps customers make better purchasing decisions that allows users to manipulate 3D virtual models online. The stores participate in the 3D virtual mall by communicating with a mall management. The 3D virtual mall allows shoppers to perform actions across multiple stores simultaneously such as viewing product availability. The mall management can authenticate clients on all stores participating in the 3D virtual mall while only requiring clients to provide authentication information once. 3D virtual shopping online mall convenient and easy process allow consumers directly buy goods or services from a seller in real-time, without an intermediary service, over the Internet. The virtual mall with an active 3D model is implemented by using 3D Language (VRML) and asp.net as the script language for shopping online pages
Synchronization Reveals Topological Scales in Complex Networks (2006)

We study the relationship between topological scales and dynamic time scales in complex networks. The analysis is based on the full dynamics towards synchronization of a system of coupled oscillators. In the synchronization process, modular structures corresponding to well-defined communities of nodes emerge in different time scales, ordered in a hierarchical way. The analysis also provides a useful connection between synchronization dynamics, complex networks topology, and spectral graph analysis.
Event Invitations in Privacy-Preserving DOSNs (2015)

Online Social Networks (OSNs) have an infamous history of privacy and security issues. One approach to avoid the massive collection of sensitive data of all users at a central point is a decentralized architecture. An event invitation feature – allowing a user to create an event and invite other users who then can confirm their attendance – is part of the standard functionality of OSNs. We formalize security and privacy properties of such a feature like allowing different types of information related to the event (e.g., how many people are invited/attending, who is invited/attending) to be shared with different groups of users (e.g., only invited/attending users). Implementing this feature in a Privacy-Preserving Decentralized Online Decentralized Online is non-trivial because there is no fully trusted broker to guarantee fairness to all parties involved. We propose a secure decentralized protocol for implementing this feature, using tools such as storage location indirection, ciphertext inferences and a disclose-secret-if-committed mechanism, derived from standard cryptographic primitives. The results can be applied in the context of Privacy-Preserving DOSNs, but might also be useful in other domains that need mechanisms for cooperation and coordination, e.g., Collaborative Working Environment and the corresponding collaborative-specific tools, i.e., groupware, or Computer-Supported Collaborative Learning.
Polarized Helper-T-Cell Responses against<i>Leishmania major</i>in the Absence of B Cells (1999)

B-cell-to-T-cell signaling can shape helper T (Th) cell responses. During infection with Leishmania major, Th response is critical in determining the outcome of disease. Resistance depends on the generation of a protective Th1 response, while susceptibility is mediated by the generation of a Th2 response. In this study, we determined whether B cells are required for the development of polarized Th1 and Th2 responses during infection with L. major. Mice lacking B cells due to disruption of the immunoglobulin M locus (microMT) were infected with L. major, and disease progression and Th cell development were assessed. On the genetically resistant C57BL background, both wild-type and microMT mice controlled the infection and mounted a Th1 response. On the genetically susceptible BALB/c background, both wild-type and microMT mice were susceptible to infection and generated Th2 responses. Thus, during L. major infection, neither direct antigen presentation or costimulation by B cells nor antibody-mediated effector functions are essential for the development of polarized Th responses.
A multi-paradigm layered architecture for synchronous distance learning (2002)

We define a layered multi-viewpoint structuring approach for the development of network-based distance learning (called telelearning) applications. The proposed approach covers the functional, architectural and technological views involved in such applications. We also identify three interaction levels: cooperation, coordination and communication and define generic functions related to each level for telelearning applications. We define MPLA, a multi-paradigm layered architecture that uses different technologies for implementation, integration and distribution of application's components. MPLA has been adopted to implement the CGTL (Co-operative Generic Tele-Learning) toolkit, usable for various synchronous collaborative groups.
Graph connectivity measures for unsupervised word sense disambiguation (2007)

Word sense disambiguation (WSD) has been a long-standing research objective for natural language processing. In this paper we are concerned with developing graph-based unsupervised algorithms for alleviating the data requirements for large scale WSD. Under this framework, finding the right sense for a given word amounts to identifying the most "important" node among the set of graph nodes representing its senses. We propose a variety of measures that analyze the connectivity of graph structures, thereby identifying the most relevant word senses. We assess their performance on standard datasets, and show that the best measures perform comparably to state-of-the-art.
An immunologic study on age-related macular degeneration. (1993)

Forty-one patients with age-related macular degeneration (AMD) were detected for serum autoantibodies against normal human retinal protein by means of Western immunoblot analysis. Twenty-seven out of the 41 patients showed positive response, with a rate of 66 per cent. The positive rate of anti-retinal antibody in the AMD patients was significantly higher than that in normal controls (18%) and in patients with other retinal diseases (24%) (p < 0.0005). These antiretinal antibodies from the AMD patients partly reacted with the retinal protein of molecular weight between 28 and 32 Kd, partly with Mr of 38 to 42 Kd, 48 to 52 Kd, 62 to 65 Kd or 110 to 130 Kd. Of them, the antiretinal antibody against the protein with Mr of 28 to 32 Kd in the AMD patients was higher than in normal controls (p < 0.05). Two or more antibodies were found in the serum from AMD patients, showing a significant difference between the patients and the controls (p < 0.005). The results indicated that in the occurrence of AMD and/or during its developing process there were inflammation and immunological response, involving antibodies against retinal proteins of various molecular weight.
IL-1β–specific recruitment of GCN5 histone acetyltransferase induces the release of PAF1 from chromatin for the de-repression of inflammatory response genes (2013)

To determine the functional specificity of inflammation, it is critical to orchestrate the timely activation and repression of inflammatory responses. Here, we explored the PAF1 (RNA polymerase II associated factor)-mediated signal- and locus-specific repression of genes induced through the pro-inflammatory cytokine interleukin (IL)-1β. Using microarray analysis, we identified the PAF1 target genes whose expression was further enhanced by PAF1 knockdown in IL-1β-stimulated HepG2 hepatocarcinomas. PAF1 bound near the transcription start sites of target genes and dissociated on stimulation. In PAF1-deficient cells, more elongating RNA polymerase II and acetylated histones were observed, although IL-1β-mediated activation and recruitment of nuclear factor κB (NF-κB) were not altered. Under basal conditions, PAF1 blocked histone acetyltransferase general control non-depressible 5 (GCN5)-mediated acetylation on H3K9 and H4K5 residues. On IL-1β stimulation, activated GCN5 discharged PAF1 from chromatin, allowing productive transcription to occur. PAF1 bound to histones but not to acetylated histones, and the chromatin-binding domain of PAF1 was essential for target gene repression. Moreover, IL-1β-induced cell migration was similarly controlled through counteraction between PAF1 and GCN5. These results suggest that the IL-1β signal-specific exchange of PAF1 and GCN5 on the target locus limits inappropriate gene induction and facilitates the timely activation of inflammatory responses.
High-Efficiency Optical Parametric Oscillator Based on Stimulated Brillouin Scattering Pulse Shaping (2019)

We present an optical parametric oscillator (OPO) that uses a pump pulse shape tailored by stimulated Brillouin scattering. The theoretical analysis is carried out for comparison between Gaussian pump and the step function pulse pump. The steep leading edge of the pulse helps minimize the buildup time of the OPO when applied to step function pulse. The study then focuses on obtaining step function pulse through stimulated Brillouin scattering pulse compression. With this control of the pump pulse's temporal shape, the experimental OPO energy conversion efficiency is 34.3%. Compared with an OPO pumped by a Gaussian-shaped pulse, the oscillation threshold is reduced and the energy conversion efficiency is improved by around 10%.
ZO-1 controls endothelial adherens junctions, cell–cell tension, angiogenesis, and barrier formation (2015)

Intercellular junctions are crucial for mechanotransduction, but whether tight junctions contribute to the regulation of cell-cell tension and adherens junctions is unknown. Here, we demonstrate that the tight junction protein ZO-1 regulates tension acting on VE-cadherin-based adherens junctions, cell migration, and barrier formation of primary endothelial cells, as well as angiogenesis in vitro and in vivo. ZO-1 depletion led to tight junction disruption, redistribution of active myosin II from junctions to stress fibers, reduced tension on VE-cadherin and loss of junctional mechanotransducers such as vinculin and PAK2, and induced vinculin dissociation from the α-catenin-VE-cadherin complex. Claudin-5 depletion only mimicked ZO-1 effects on barrier formation, whereas the effects on mechanotransducers were rescued by inhibition of ROCK and phenocopied by JAM-A, JACOP, or p114RhoGEF down-regulation. ZO-1 was required for junctional recruitment of JACOP, which, in turn, recruited p114RhoGEF. ZO-1 is thus a central regulator of VE-cadherin-dependent endothelial junctions that orchestrates the spatial actomyosin organization, tuning cell-cell tension, migration, angiogenesis, and barrier formation.
Trace Element Analytical Chemistry in the People's Republic of China (1983)

Trace Element Analytical Chemistry in the People's Republic of China was published in Volume 2 Proceedings of the Second International Workshop Neuherberg, Federal Republic of Germany, April 1982 on page 555.
Superblock FTL (2010)

In NAND flash-based storage systems, an intermediate software layer called a Flash Translation Layer (FTL) is usually employed to hide the erase-before-write characteristics of NAND flash memory. We propose a novel superblock-based FTL scheme, which combines a set of adjacent logical blocks into a superblock. In the proposed Superblock FTL, superblocks are mapped at coarse granularity, while pages inside the superblock are mapped freely at fine granularity to any location in several physical blocks. To reduce extra storage and flash memory operations, the fine-grain mapping information is stored in the spare area of NAND flash memory. This hybrid address translation scheme has the flexibility provided by fine-grain address translation, while reducing the memory overhead to the level of coarse-grain address translation. Our experimental results show that the proposed FTL scheme significantly outperforms previous block-mapped FTL schemes with roughly the same memory overhead.
Melanocytic tumors : a guide to diagnosis (1997)

Introduction and basic considerations common Nevi blue Nevi and related lesions Spitz and related Nevi histology of common forms of cutaneous melanoma variants of primary cutaneous melanoma that stimulates other melanocytic and non-melanocytic lesions metastatic melanoma characteristics that relate to prognosis techniques in the evaluation of metanocytic lesions (with a section by Sunita Bhuta) the diagnosis of melanocytic tumours an algorithm for the diagnosis of compound melanocytic tumours (located in the epidermis and subepidermal tissues) an algorithm for the diagnosis of melanocytic tumours in the dermis and/or subcutaneous tissues.
Cells and Membranes (2010)

Nanoindentation of biological cells and thin biomembranes has been demonstrated to be an effective means for measuring and understanding the mechanical behavior of these bio-entities with relatively small dimensions and unusual mechanical properties. Several new and variant indentation techniques have been developed recently. New solid mechanics models spanning multi-scale indentation deformation are constructed to analyze the force-displacement data so that the quantitative materials parameters can be found.
本德穹隆-沃思堡盆地巴尼特-古生界总油气系统的巴尼特页岩地质格架 (2007)

为了划定巴尼特页岩油气资源评价的两个地理区，本文描述了本德穹隆-沃思堡盆地巴尼特页岩和巴尼特-古生界总油气系统（TPS）的基本地质特征和有关标准。美国地质调查所对这两个地区（又称“评价单元”）进行评价后，预测巴尼特页岩约有26万亿立方英尺（平均值）待发现的技术可采天然气储量。 密西西比系巴尼特页岩是本德穹隆-沃思堡盆地古生界油气藏所产油气的主要源岩，也是得克萨斯州最重要的产气层。根据测井和商业数据库绘制的图件和石油地球化学分析结果，巴尼特页岩在本德穹隆-沃思堡盆地的大部分地区都富含有机质且达到了生烃的热成熟度条件。在与曼斯特（Muenster）穹隆毗邻的本德穹隆一沃思堡盆地东北部构造最深的地区，这套页岩的厚度超过了1000英尺（305米）而且有厚层灰岩互层，而向西其厚度在密西西比系查普尔（Chapped陆架上迅速减薄至几十英尺厚。 巴尼特-古生界TPS是在热成熟的巴尼特页岩有大量油气生成的范围划定的，而且这些油气分布于巴尼特页岩的非常规连续型油气藏内，同时也可以运移并聚集在许多常规的古生界碎屑岩-碳酸盐岩储层中。镜质体反射率（Ro）的测量值与目前的埋深几乎没有关联。巴尼特页岩的等Ro曲线和其所生成的烃类类型都表明这个地区曾发生过重要的抬升和侵蚀作用。另外，在沃希托冲断带前缘和米纳勒尔韦尔斯一纽瓦克东断层系统发生的热液事件也增强了这套页岩的热作用。 根据地层和热成熟度可将巴尼特页岩分为以下两个产气评价单元：（1）大范围的纽瓦克东裂缝遮挡连续型巴尼特页岩气评价单元，它含有一个最有利的产气区，其中的巴尼特页岩厚度较大（大于91米），位于热作用生气窗（Ro≥1．1％）内，其上、下都有致密不渗透的灰岩层。（2）扩大的�
Computational Complexity of Multiple Sequence Alignment with SP-Score (2001)

It is shown that the multiple alignment problem with SP-score is NP-hard for each scoring matrix in a broad class M that includes most scoring matrices actually used in biological applications. The problem remains NP-hard even if sequences can only be shifted relative to each other and no internal gaps are allowed. It is also shown that there is a scoring matrix M(0) such that the multiple alignment problem for M(0) is MAX-SNP-hard, regardless of whether or not internal gaps are allowed.
A modified refractometer method as a practical aid to the epidemiological investigation of disease in the neonatal ruminant (1975)

A refractometer method for use on the farm, by the practising veterinary surgeon, to allow estimation of immunoglobulin levels of neonatal calf and lamb plasma is described. The results show that a good correlation exists between values obtained by this method and those obtained by the standard zinc sulphate turbidity method.
NINTENDO SURGERY: Laparoscopic Techniques Increase in Popularity (1994)

Get PDF Email Share Share with Facebook Tweet This Post on reddit Share with LinkedIn Add to CiteULike Add to Mendeley Add to BibSonomy Get Citation Copy Citation Text MICHAEL THOMAS, "NINTENDO SURGERY: Laparoscopic Techniques Increase in Popularity," Optics & Photonics News 5(7), 6-7 (1994) Export Citation BibTex Endnote (RIS) HTML Plain Text Citation alert Save article
Coup d' il (2001)

Journal Article Coup d’œil Get access Steven Harris Steven Harris Search for other works by this author on: Oxford Academic Google Scholar Oxford Art Journal, Volume 24, Issue 1, 2001, Pages 89–111, https://doi.org/10.1093/oxartj/24.1.89 Published: 01 March 2001
Novel tyrosine-kinase inhibitors for the treatment of chronic myeloid leukemia: safety and efficacy (2018)

Chronic myeloid leukemia (CML) is characterized by a pathognomonic chromosomal translocation, which leads to the fusion of breakpoint cluster region (BCR) and Abelson leukemia virus 1 (ABL1) genes, generating an oncoprotein with deregulated tyrosine kinase activity. Areas covered: In the last two decades, BCR/ABL1 kinase has become the molecular target for tyrosine kinase inhibitors (TKIs), a class of drugs that impressively improved overall survival. Despite these results, a proportion of patients experiences resistance to TKIs and need to change treatment. Furthermore, TKIs are unable to eradicate leukemic stem cells, allowing the persistence of neoplastic clones. Therefore, there is still clinical need for new agents to overcome common resistance mechanisms to available drugs. This review explores the horizon of drugs actually under investigation for CML patients resistant to conventional treatment. Expert commentary: Radotinib is an ATP-competitive TKI that showed significant activity also in front-line setting and could find employment indications in CML. Asciminib, an allosteric ABL1 inhibitor, could demonstrate a higher capacity in overcoming common TKIs resistant mutations, including T315I, but clinical findings are needed. CML stem cell target will probably require new therapeutic strategies: combinations of several compounds acting with different mechanisms of action are actually under investigation.
Stability of A Surcharged Tunnel under the Effect of Pre-Loading on the Adjacent Braced Wall (2008)

When the ground is excavated adjacent to the existing tunnel, which is loaded by the surcharge on the ground surface, the tunnel stability would be very sensitive to the deformation of the ground induced by the horizontal displacement of braced wall. The stability of the existing surcharged tunnel could be controlled by pre-loading on the braced wall. In this paper, it was investigated, if it would be possible to keep the existing surcharged tunnel stable by preventing the horizontal displacement of a braced wall by imposing the pre-loading during the ground excavation. For this purpose, large scale model tests were performed in a scale 1/10 at the test pit which was 2.0m in width and 6.0m in height and 4.0m in length. Isotropic test ground was constructed homogeneously by wet sand. Model tunnel was constructed in the test ground. Surcharge was loaded on the ground surface above the tunnel. During the tests, the behavior of model tunnel and model braced wall was measured. Numerical analyses were also performed in the same condition as the tests. And their results were compared to that of the model tests. Consequently, the effect of a surcharge could be compensated by imposing the pre-loading on the braced wall. The existing tunnel and the braced wall could be kept stable by preventing the horizontal displacement of the braced wall through pre-loading, although the tunnel is surcharged.
The Effect of the Thermal Stress on Wellbore Stability (1998)

Abstract The thermal stress near the wellbore occurs because the temperature near the wellbore is changed by mud in well. The stress distribution near the wellbore is changed by the thermal stress, Eventually, the wellbore stability is affected. So, in this paper, first the integral equations of the thermal stress caused by varied temperature near the wellbore are derived from the thermoelastic theory. Then, the numerical computation is conducted for the thermal stress equations with the numerical results simulated for the temperature field near the hole. The plots of radius thermal stress distribution is obtained as a function of time. Further, the thermal stress is stacked with the pure mechanical stress near wellbore. Finally, the effect of the thermal stress on the wellbore stability is analyzed by use of the Mohr-Coulumb criterion for the any drilling condition and any time. The simulated result shows that the tangential and axial thermal stress on the holel formation interface may make the total effective stress to decrease on it below some point of section, and make the total effective stress to increase up some point. It is an important influence on the stress distribution near the wellbore. Therefore, the theories and simulated results in this paper have a guiding signification for the wellbore stability in the high temperature well and for the recovery of the production, such as the fracturing, injection, and thermal production. P. 85