gebhart/patrepeval huggingface dataset:
A hitherto unreported paramyxovirus of turkeys. (1979)

A newly isolated avian virus is described which was obtained from a flock of laying turkey hens with respiratory disease and accompanying egg production drop. Characterisation of the virus indicated it to be of the paramyxovirus group and to be related through antigenic crossing with Newcastle disease virus. Examination of turkey sera from five separate flocks indicated natural infection with the paramyxovirus to be relatively widespread. Experimental infection of turkeys produced only mild respiratory disease.
1.5 V 10-12.5 GHz integrated CMOS oscillators (2003)

As both wireless and optical communications systems move towards high-data-rate applications, high-frequency low-phase-noise oscillators are important building blocks in the receiver and transmitter design. CMOS oscillators with integrated inductors are therefore well suited for such applications. This paper describes two integrated CMOS LC oscillators designed for operation over 10 GHz. The first one is based on the ring-coupled quadrature VCO configuration with wide tuning range, while the other is a 4-stage ring oscillator using inductive load. Fabricated in a 0.25-/spl mu/m CMOS technology, both oscillators can operate from a single supply voltage as low as 1.5 V. The highest operating frequencies for the quadrature VCO and ring oscillator are 11 and 12.55 GHz, respectively.
Young, pregnant ... and pleased. (1999)

This article presents the factors associated with the increased risk of poor obstetric outcome. The incidence of pregnancy is certainly higher among young women who are achieving poorly in school or in care. Women under the age of 17 are often seen as being obstetrically at high risk. However the majority of studies on the physiology of teenage pregnancy found no correlation between age alone and poor obstetric outcome. The seemingly poor birth outcomes of teenage mothers appear to result largely from their adverse socioeconomic circumstances and not from young maternal age per se. Poverty poor nutrition and poor housing have all been shown to be associated with poor outcomes in pregnancy. Since pregnancy and childbearing have been matters of national concern a particular slant has consistently been adopted. The focus was on the quality of mothering and sex education. However this was opposed since what young people learn about sex at school will inevitably only be a fraction of what they actually assimilate about sex and sexuality. Peer group the media their immediate family and broader social and cultural influences will all have a part to play in how adolescents behave. This article also presents teenage adolescents experiences during their pregnancy.
The effect of short rotation desmodium distortum planted fallow on the productivity of ultisols in Centre Cameroon (2004)

In order to investigate the effect of short rotation Desmodium distortum planted fallow on maize grain yield and soil properties, an experiment was conducted over four consecutive years (1995-1998) at two locations (Minkoameyos in the humid forest zone and Ntui in the forest-savannah transition zone) in Centre Cameroon. The experimental design for each year was made of four replications and three treatments: i) Natural Fallow used as control (NF), ii) Desmodium Fallow (DF) and iii) Soybean (Glycine max) Rotation (SR). Maize (Zea mays) was used as plant test and was planted each year in the first cropping season (March-June) followed by each treatment from July to February. The analysis of variance and mean separation (Tukey's HSD) were used to evaluate the effects of treatments on maize yield and soil chemical properties at the end of the experiment. No treatment could produce relatively more than the first year of the experiment where maize yields were based on 7-8 year-old natural fallow in both sites. However, in Minkoameyos, there was a significant difference (p= 0.043) between the treatments in the fourth year. Desmodium plots out-yielded both natural fallow and soybean plots. In Ntui, there was a highly significant difference (p= 0.000) among treatments in the third and fourth years. Desmodium plots also outyielded both natural fallow and soybean plots; while natural fallow plots out-yielded soybean plots. The general trend of productivity was ranked as: DF> NF> SR. Apart from the available P that has shown a highly significant difference (p= 0.000) compared to the initial value and to other treatments, no other significant difference was noticed with other soil properties in both sites. However, the general trend is that most soil chemical properties tended to decrease excepted pH water and available phosphorus. The study has shown that, in forest-savannah–transition zone (Ntui), Desmodium distortum had highly significant effect on maize grain yield from the third year while in the forest zone (Minkoameyos), the effect of Desmodium was significant from the fourth year. This therefore, suggests that the Desmodium shrub has a potential for improving plant nutrient availability in these soils when used in short rotational fallow system.
3D Printed Tactile Learning Objects: Proof of Concept (2014)

Image-based learning objects produced today are primarily designed for the virtual world and are not easily accessible to blind or visually impaired students. The opportunity to 3D print images from disciplines such as anatomy, histology, cell biology, astronomy, and geology has opened new vistas for the construction of tactile learning objects made for the real world rather than the digital world. This paper provides a “proof of concept” for the idea of more widespread production of tactile learning objects mirroring the design of virtual learning objects, especially in STEM (science, technology, engineering, and math) disciplines where there is heavy use of images from microscopes, telescopes, and satellites. Evidence promoting the production of 3D printed braille is also provided. It is further suggested that many virtual learning objects may need to be redesigned using 3D printing so they may be made touchable for a more complete tactile learning experience.
Antispasmodic ortho-Substituted Phenoxyalkylamines (1966)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAntispasmodic ortho-Substituted PhenoxyalkylaminesK. Rubinstein, N. Elming, J. Fakstorp, K. Hermansen, J. G. A. Pedersen, and T. Natvig JacobsenCite this: J. Med. Chem. 1966, 9, 6, 804–809Publication Date (Print):November 1, 1966Publication History Published online1 May 2002Published inissue 1 November 1966https://pubs.acs.org/doi/10.1021/jm00324a002https://doi.org/10.1021/jm00324a002research-articleACS PublicationsRequest reuse permissionsArticle Views112Altmetric-Citations7LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
<i>MotifAnalyzer‐PDZ</i>: A computational program to investigate the evolution of PDZ‐binding target specificity (2019)

Recognition of short linear motifs (SLiMs) or peptides by proteins is an important component of many cellular processes. However, due to limited and degenerate binding motifs, prediction of cellular targets is challenging. In addition, many of these interactions are transient and of relatively low affinity. Here, we focus on one of the largest families of SLiM-binding domains in the human proteome, the PDZ domain. These domains bind the extreme C-terminus of target proteins, and are involved in many signaling and trafficking pathways. To predict endogenous targets of PDZ domains, we developed MotifAnalyzer-PDZ, a program that filters and compares all motif-satisfying sequences in any publicly available proteome. This approach enables us to determine possible PDZ binding targets in humans and other organisms. Using this program, we predicted and biochemically tested novel human PDZ targets by looking for strong sequence conservation in evolution. We also identified three C-terminal sequences in choanoflagellates that bind a choanoflagellate PDZ domain, the Monsiga brevicollis SHANK1 PDZ domain (mbSHANK1), with endogenously-relevant affinities, despite a lack of conservation with the targets of a homologous human PDZ domain, SHANK1. All three are predicted to be signaling proteins, with strong sequence homology to cytosolic and receptor tyrosine kinases. Finally, we analyzed and compared the positional amino acid enrichments in PDZ motif-satisfying sequences from over a dozen organisms. Overall, MotifAnalyzer-PDZ is a versatile program to investigate potential PDZ interactions. This proof-of-concept work is poised to enable similar types of analyses for other SLiM-binding domains (e.g., MotifAnalyzer-Kinase). MotifAnalyzer-PDZ is available at http://motifAnalyzerPDZ.cs.wwu.edu.
Synthesis and magnetic properties of Ni-Zn ferrite @polyaniline/epoxy composites for embedded inductor applications (2011)

The development of the electronic industry and electronic technology is proceeding in the direction of miniaturization and high frequency. The embedded passives technology, as a key technology in system-in-package mode, throws new light on improving the package of the passives. Much works have been done to develop embedded passives. For inductors, Ni-Zn ferrites with soft magnetic are ideal materials for preparing the magnetic composite materials. In this study, Ni-Zn ferrite was prepared by a chemical coprecipitation method, then was oxidative polymerization of aniline in aqueous solution and made the Ni <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">0.5</sub> Zn <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">0.5</sub> Fe <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> O <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">4</sub> @polyaniline (NZF@PANi) core-shell particles. The obtained particles were characterized by X-ray diffraction (XRD). The magnetic epoxy composites were fabricated by mixing the core-shell particles and epoxy resin matrix. The dielectric and magnetic properties of the composites were measured by impedance analyzer (Agilent E 4991 A: 1 MHz to 1 GHz). The initial complex permeability value obtained from the toroidal sample exhibit good frequency stability and the permeability loss was low. The permeability of the epoxy composite was rising from 1.4 to 2.2 with the mass fraction of the ferrite increasing in the composite from 3%-70%.
Design of Perforated Risers to Control Dewatering of Sedimentation Basins (1993)

Sedimentation basins intercept and detain storm runoff from earth disturbance sites to facilitate gravitational settling of suspended sediment. Designing sedimentation basins to control the period of dewatering is an important sediment removal efficiency consideration. A design and analysis procedure is derived which evaluates dewatering of perforated-riser controlled sedimentation basins. This development assumes the basins stage-storage relationship can be assumed to be linear in the water-storage zone. The theory is applied to three specific sedimentation basins, each with different degrees of nonlinearity of the stage-storage relationship. Actual dewatering of basins with linear or nearly linear stage-storage relationships is very well represented by the theory developed. Actual dewatering of basins with non-linear stage-storage relationships is slightly faster (up to 11% for the basin evaluated) than predicted using the theory developed herein.
Towards a Generalized Architecture for the Integration of Tools in LMSs (2009)

In this article we introduce the main components of a generalized architecture to facilitate the integration of tools in LMSs. This proposal tries to improve the reuse possibilities of the tools in e-learning systems. Reusability has been suggested as a key solution to reduce the high costs of the development of educational experiences in e-learning systems. Up to now, reutilization has focused mainly on the educational contents around metadata standards, contents formats, packaging systems, etc. However, educational practices usually involve tools to facilitate the communication, collaboration and work of students and teachers as well. This proposal is part of a wider solution based on the language PoEML, in which not only the possibility of the inclusion of tools in LMSs is considered, but also the management of its utilization.
Adsorption Coefficients of Eight Pesticides for Citrus Orchard Soils with Different Soil Organic Matter (2000)

This study was carried out to determine the adsorption characteristics of eight pesticides on thirty citrus orchard soil so soil samples were taken from nineteen soil series containing different fractions of organic carbon(Foc). The adsorption characteristics for eight pesticides fitted to Freundlich isotherms. The adsorption isotherms showed C-type for alachlor and chlorpyrifos, L-type for linuron and diniconazole. and S, C, and L-types for metribuzin, metolachlor, and alachlor with increasing Foc, respectively. In particular, the adsorption of chlorothalonil showed S, C, L, and H-types with increasing Foc. Distribution coefficient(Kd) values of metribuzin, metolachlor, and alachlor were below and increased linearly with Foc. Kd values of linuron, diuron and chlorothalonil increased exponentially to 60, 200, and , respectively and those of diniconazole and chlorpyrifos increased logarithmically. Kf value. Freundlich adsorption coefficiient, increased with Kd in the same manner with Kd. Furthermore, the linearity of Kf value was larger than that of Kd value.
Amantadine treatment following traumatic brain injury in children (2007)

The studies reviewed for this paper suggest that amantadine is clinically beneficial for children who have sustained head injuries. Double blind placebo controlled trials with larger sample sizes are needed to further substantiate these findings.
BIOCHEMICAL STUDIES ON ADENOVIRUS MULTIPLICATION, VI. PROPERTIES OF HIGHLY PURIFIED TUMORIGENIC HUMAN ADENOVIRUSES AND THEIR DNA's (1964)

Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans the biological, physical, and social sciences.
Interferon gamma rapidly induces in human monocytes a DNA-binding factor that recognizes the gamma response region within the promoter of the gene for the high-affinity Fc gamma receptor. (1992)

Interferon gamma (IFN-gamma) transcriptionally activates several early-response genes in monocytes that are important for the ultimate phenotype of the activated macrophage. One of these genes is the high-affinity Fc receptor for IgG (Fc gamma RI). Recently, Pearse et al. [Pearse, R.N., Feinman, R. & Ravetch, J. V. (1991) Proc. Natl. Acad. Sci. USA 88, 11305-11309] defined within the promoter region of the Fc gamma RI gene an element, the gamma response region, which was necessary for IFN-gamma-induced enhancement of Fc gamma RI. In this report we describe the induction by IFN-gamma of a DNA-binding factor, FcRF gamma (Fc gamma RI DNA-binding factor, IFN-gamma induced), that specifically recognizes the gamma response region element. Electrophoretic mobility shift assays (EMSAs) demonstrated the presence of FcRF gamma in human monocytes within 1 min after exposure to IFN-gamma. On EMSA, FcRF gamma consisted of two complexes termed FcRF gamma 1 and FcRF gamma 2. The nuclear concentration of FcRF gamma rapidly increased, peaked at 15 min, and then fell after 1-2 hr. Dose-response studies revealed (i) as little as 0.05 ng of IFN-gamma per ml induced FcRF gamma, (ii) maximum activation occurred at 1 ng/ml, and (iii) steady-state levels of Fc gamma RI mRNA closely paralleled that of FcRF gamma. Since FcRF gamma was activated in cells normally not expressing Fc gamma RI RNA, other regulatory mechanisms must control Fc gamma RI-restricted tissue expression. Activation of FcRF gamma by IFN-gamma was inhibited by pretreatment with 500 nM staurosporin and 25 microM phenyl arsine oxide. These data suggest that a kinase and possibly a phosphatase activity are required for IFN-gamma-induced signaling of FcRF gamma in monocytes.
Competitive Relationships Among Potato Production Areas in Northeastern America (2005)

Agribusiness
Static and Dynamic Study of the Performance of Multicast in Ad Hoc Networks Using ODMRP Protocol (2017)

An ad hoc network is a collection of wireless mobile nodes dynamically forming a temporary network without the use of any preexisting network infrastructure or centralized administration.On Demand Multicast Routing protocol (ODMRP) is a multicast routing protocol for mobile ad hoc networks.Its efficiency, simplicity, and robustness to mobility renders it one of the most widely used MANET multicast protocols.In this paper, our proposed scheme presents two different scenarios (static and dynamic) used to study the performance of ODMRP as a multicast routing protocol based on mesh topology and fmally concluded that protocol operates well in dynamic environment than in static one because the mobile node has a better packet delivery ratio than in static scenario.
A comparison of 13C nuclear magnetic resonance and 14C tracer studies of hepatic metabolism. (1981)

The gluconeogenic pathway from 13C-labeled substrates, each of which contained the 14C-labeled counterpart at a tracer level, has been followed in isolated rat liver cells and in isolated perfused mouse liver. The gluconeogenic flux from glycerol, the synthesis of glycogen, the stimulation of glycogenolysis by glucagon, the recycling of triacylglycerol, and an increase in pentose cycle activity under the influence of phenazine methosulfate were all observed directly in the 13C NMR spectra of perfused liver or isolated hepatocytes. The relative concentrations of 13C label at specific carbons measured by the NMR spectra under these conditions agreed closely with 14C isotopic distributions measured in extracts of the same doubly labeled samples for specific activities of greater than or equal to 3%. The label distributions measured by both methods were the same to within the experimental errors, which ranged from +/- 2% to +/- 7% in these experiments.
Effects of Organization-Public Relationship of Corporate Donation via SNS on Corporate image and Reputation (2017)

본 연구는 기업의 SNS 기반 기부활동에 참여한 SNS 이용자 228명을 대상으로 조직-공중관계성과 기업이미지 및 기업평판의 관계를 검토하였다. 이를 위해 SPSS 21 프로그램과 AMOS 21프로그램을 이용, 상관관계 분석과 신뢰도 분석, 그리고 구조모형분석을 실시하였다. 주요 결과를 제시하면 다음과 같다. 첫째, SNS 이용자의 조직-공중관계성과 기업이미지의 관계를 살펴본 결과, 조직-공중관계성은 기업이미지에 통계적으로 유의한 정(+)의 영향을 미치는 것으로 나타났다. 둘째, SNS 이용자의 조직-공중관계성과 기업평판의 관계를 살펴본 결과, 조직-공중관계성은 기업의 평판에 통계적으로 유의한 정(+)의 영향을 미치는 것으로 확인되었다. 셋째, SNS 이용자의 기업이미지와 기업평판의 관계를 살펴 본 결과, 기업이미지는 기업의 평판에 통계적으로 유의한 정(+)의 영향을 미치는 것으로 나타났다. 이상의 결과는 향후 기업의 소셜네트워크 기반 마케팅 전략을 구축하는데 기여할 것으로 판단된다.
THE INHIBITORY EFFECTS OF CUMIN ALDEHYDE ON AMYLOID FIBRILLATION AND CYTOTOXICITY OF ALPHA-SYNUCLEIN (2012)

Objective: Alpha-synuclein is a major component of protein plaques in synucleinopathies, particularly Parkinson’s disease. The purpose of this study is to assess the inhibitory effects of cuminaldehyde on the fibrillation of alpha-synuclein. Methods: Alpha-synuclein was expressed in Escherichia coli and subsequently purified. For the process of fibrillation, purified protein was incubated at 37 ◦ C and pH 7.2. Fibrillation was analyzed by the standard fibril methods. The effects of different concentrations of cuminaldehyde (20-500 μM) on alpha-synuclein fibrillation were studied by assessment of the cytotoxic effects of samples on the neuroblastoma cell line, SK-N-MC. To study the protein aggregation forms that were generated in the presence of cuminaldehyde, SDS resistance and induced fibrillation (seeding) methods were employed. For studying its specificity on alpha-synuclein, the effect of cuminaldehyde on lysozyme fibrillation was also examined. Results: We showed, for the first time, that cuminaldehyde inhibited fibrillation by more than 80%. The highest inhibition was observed at the ratio of 5-15 moles of drug to protein. The viability of the treated cells with inhibited proteins was more than 90%, whereas non-inhibited samples caused a decrease in viability by 50%. Inhibited samples were not resistant to SDS and they were unable to induce fibrillation. Cuminaldehyde did not inhibit lysozyme fibrillation. Conclusion: Cuminaldehyde inhibited fibrillation of alpha-synuclein which was accompanied by small amorphous aggregated particles of alpha synuclein. The inhibited protein samples did not induce aggregation. Thus, cuminaldehyde can be considered as a candidate to inhibit the formation of alpha-synuclein plaques.
Evidence that NMDA-dependent limbic neural plasticity in the right hemisphere mediates pharmacological stressor (FG-7142)-induced lasting increases in anxiety-like behavior (1998)

The findings of this study support the hypothesis that N-methyl-D-aspartate (NMDA) receptors mediate the initiation of long-term potentiation (LTP) and behavioral changes induced by the anxiogenic beta-carboline, FG-7142. Unlike previous work, this study examined the effects of FG-7142 on LTP of amygdala efferents in both hemispheres. 7-amino-phosphono-heptanoic acid (AP7), a competitive NMDA receptor blocker, given prior to administration of FG-7142, prevented LTP in amygdala efferent transmission to the medial hypothalamus and periacqueductal gray (PAG). When given FG-7142 alone, cats showed lasting behavioral changes accompanied by LTP in all pathways studied. Duration of LTP, and its relationship to behavioral change, depended on the pathway and the hemisphere of the pathway. Correlation and covariance analyses indicate that LTP in the left amygdalo-ventromedial hypothalamic pathway mediates initiation, but not maintenance, of increased defensiveness. This finding replicates previous work. A new finding is that increased local excitability in the right basal amygdala (reduced threshold for evoked response), and LTP in the right amygdalo-PAG pathway, may be important for maintenance of increases in defensive behavior. Furthermore, the effects of flumazenil, a benzodiazepine receptor antagonist, on behavior and physiology single out the importance of right amygdalo-PAG LTP as a critical mediator of increased defensiveness. Flumazenil reversed the increase in defensiveness produced by FG-7142 in a drug-dependent manner as described in Adamec (1998a). Moreover, flumazenil reversed LTP only in the right amygdalo-PAG pathway. The findings of the present study suggest that response to FG-7142 may be a useful model of the effects of traumatic stressors on limbic system function in anxiety, especially in view of the recent data in humans implicating right hemispheric function in persisting negative affective states.