gebhart/patrepeval huggingface dataset:
Downhill slopes look shallower from the edge (2009)

A dramatic failure of orientation constancy is documented in the perception of downhill slopes. Contrary to naïve expectation, steep downhill slopes look shallower from the edge than they do from back from the edge. Three experiments document and quantify this failure of constancy for real and virtual surfaces using a variety of dependent measures. Two additional studies document overestimation of both non-visually perceived head pitch and perceived gaze declination. A model of orientation constancy failure is fit to the data that combine exaggerations in perceived gaze declination with exaggerated scaling of perceived optical slant. These findings support a functional scale-expansion model of error in slope perception.
Noise Reduction Technique Through Bandwidth Switching for Switched-Capacitor Amplifier (2015)

The conventional switched-capacitor amplifier faces design tradeoffs between settling accuracy and noise, in that high settling accuracy demands wide bandwidth but at the sacrifice of noise performance. In fact settling accuracy and noise exhibit different time dependence, which can be exploited to optimize the overall performance. Settling accuracy is determined by average bandwidth in the whole amplification phase, whereas the output noise of interest is determined by the bandwidth near the end of the phase. The proposed amplifier divides the amplification phase into two sub-phases. The first sub-phase starts with high bandwidth and high slew rate to approach the final value quickly. In the second sub-phase, the bandwidth can be significantly reduced, achieving the target settling accuracy but with much lower noise. This division allows the settling accuracy, noise, slew rate, and DC gain to be designed independently. A test chip is fabricated in a 65 nm CMOS process and operates at 90 MS/s. Measurements demonstrate that the proposed amplifier achieves 45% noise power reduction in the amplification phase along with improved linearity and lower power consumption, when compared with the conventional amplifier.
All Melbourne Matters - Researching the Church in Melbourne (2009)

The Christian Research Association, together with the organisation 'Transforming Melbourne', has released a series of 32 reports on the churches and communities in greater Melbourne. The research utilised data from the 2006 National Church Life Survey (NCLS), additional supplementary surveys undertaken by Transforming Melbourne and the Christian Research Association, and the 2006 Australian Census of Population and Housing, along with special sections written by a variety of church leaders and other researchers. As part of the project two different types of reports were written: a Citywide Report looking at the greater Melbourne area as a whole and, extended reports on each of the 31 local government areas.
Epidermal growth factor receptor inhibitors in non-small cell lung cancer: current status and future perspectives (2012)

Two classes of epidermal growth factor receptor (EGFR) inhibitors are currently available for clinical use: tyrosine-kinase inhibitors (TKIs) and monoclonal antibodies. The introduction of pharmacological agents that are able to inhibit EGFR represents an important step in the management of patients with advanced non-small cell lung cancer (NSCLC), the leading cause of cancer death worldwide. The use of EGFR inhibitors has not only led to meaningful therapeutic gains for patients, but has also expanded our knowledge about the disease itself, as it is now recognized that activating mutations of EGFR play a pathogenetic role in NSCLC, especially in adenocarcinoma, patients who never smoked or former light smokers, females, and Asian individuals. Patients with NSCLC and one or more of these features are more likely to harbor tumors with EGFR mutations, and hence to respond to TKIs, than individuals without these features. Currently, TKIs are considered by many as the treatment of first choice in both the first- and second-line treatment of patients with clinical or molecular predictors of therapeutic benefit, and chemotherapy is a second option in these cases, especially when activating mutations of EGFR are present. Moreover, TKIs and anti-EGFR antibodies may be used in other settings, and their therapeutic role in NSCLC is clearly expanding. However, despite an initially successful treatment course, patients with advanced NSCLC eventually develop resistance to TKIs; and novel agents that hold promise for the future include irreversible EGFR inhibitors with activity against resistance-conferring EGFR mutations.
BERRY FRUITS AS A SOURCE OF BIOLOGICALLY ACTIVE COMPOUNDS: THE CASE OF LONICERA CAERULEA (2007)

The potential of L. caerulea berries to prevent chronic diseases such as diabetes mellitus, cardiovascular diseases and cancer seems to be related above all to their phenolic content.
The Partially Implantable Middle Ear Implant, Case Reports (2015)

The partially implantable middle ear implant (MEI) is clinically useful for bilateral deafness when it is applied to the mixed deafness with a bone conduction threshold of 20-40 dB. Two out of five successful cases are reported. It should be noted that 1.5 years have passed without changes for the first successful implantation. The next step for application of the MEI to more cases is discussed.
Monoclonal antibody--specific immobilization of platelet antigens (MAIPA): a new tool for the identification of platelet-reactive antibodies (1987)

The analysis of sera containing different platelet-reactive antibodies, eg, autoantibodies, platelet-specific alloantibodies like anti-PIA1, -PIA2, -Baka, and HLA antibodies, is still difficult. Recently, monoclonal antibodies against major platelet membrane constituents (glycoproteins IIb/IIIa and Ib and HLA class I molecule) have become available. In this report we describe a new assay that takes advantage of these highly specific reagents to investigate selectively platelet reactive antibodies against epitopes on different glycoproteins. The reliability and specificity of this assay is demonstrated with known platelet-reactive autoantibodies and alloantibodies (anti-PIA1, -Baka, -Pen). The discovery of a PIA2 antibody in a serum of a polytransfused patient underscores the efficiency of this technique. Possible applications of this assay are discussed in detail.
Analysis of Dust Losses in Photovoltaic Modules (2011)

The current government of Ethiopia has devised supply augmented and demand management strategies in order to reduce pressure on forests and the adverse impact of indoor air pollution.This paper tries to examine and understand the determinants of the speed of adoption of one of the demand side strategies, fuel saving technologies (Mirt and Lakech), in urban Ethiopia.The result of the duration analysis shows that income level is a significant factor in the adoption decision of the technologies.This indicates that households will not shift to other better sources of energy as their income increases, as postulated by the energy ladder hypothesis.Education is positively and significantly related to the speed of adoption of Mirt biomass cook stoves but its effect on adoption of Lakech charcoal stove is insignificant.Electric Mitad (substitute for Mirt injera stove) does not have any effect on the adoption of Mirt biomass cook stoves.However, ownership of Metal charcoal stove is negatively correlated with the adoption of Lakech charcoal stoves.This may suggest that there is a need to reconsider the promotion strategy given the better performance of Lakech charcoal stove over Metal charcoal stove.The implications of other covariates have also been discussed.
Multi-component chemical defense in seahares (Gastropoda:Opisthobranchia): antipredator compounds act as both honest and deceptive signals to multiple predator species (2002)

Thesis (Ph. D.)--University of Washington, 2002
High-resolution imaging of synaptic structure with a simple confocal microscope. (1989)

We describe a straightforward modification to a conventional fluorescence microscope that permits confocal fluorescence imaging of living and fixed biological material. The modified microscope has been used to examine the morphology of presynaptic terminals at the snake neuromuscular junction. Among our observations is the presence of two discrete compartments within each terminal bouton.
The Quantab strip in the measurement of urinary chloride and sodium concentrations. (1984)

The "Quantab" strip (Ames) measures chloride in fluids. For sodium chloride solutions and urine we found very good correlations between the Quantab reading and the chloride concentration as measured by chemical assay (r = 0.95 for chloride and r = 0.85 for sodium in urine). The strip gave reproducible results over the temperature range 4 to 37 degrees C. There was very little inter- and intra-observer variation in reading the strip. Although 10 to 23 min is required to complete the reaction, the strip reading is stable thereafter. We suggest that the strip could be useful in epidemiological studies of urinary sodium concentration and clinically in helping patients adhere to a low-salt diet.
IRITIS IN FOWLS (1940)

a few remarks concerning the question.Fowl paralysis was described by
Development of USDA-FSIS Method for Isolation of Listeria monocytogenesfrom Raw Meat and Poultry (1988)

A method was developed specifically to detect naturally occurring Listeria monocytogenes in meat because the traditional cold enrichment procedure was extremely slow and other procedures were ineffective. This method could identify beta-hemolytic Listeria colonies in 3-4 days. The use of a 2-stage enrichment, highly selective LPM agar, and a thin-layer horse blood agar plate for the detection of beta-hemolytic Listeria isolates are the important steps of this method. L. monocytogenes was recovered from 20 of 41 samples of frozen ground beef, 12 of 23 samples of pork sausage, and 7 of 22 samples of poultry. These results indicate that L. monocytogenes is common in raw meat and that this method is effective for its recovery.
Ensemble approach for time series analysis in demand forecasting: Ensemble learning (2017)

Demand forecasting for replenishment is one of the main issue for retail industry in terms of optimizing stocks, minimizing costs and also for reducing stock out problem. Better forecasting for demands, means maximizing sales and result with more revenue and profit for retailers. An other critical result of the stock out problem is of course dissatisfied customers and customer churn effect to retailers as well. Customers, in general do not wish to buy an equivalent product from different brands instead of their routine selections. There are of course many parameters which affect very seriously forecasting accuracy of consumer demands. For instance; seasonality, promotional effects, social events, new trends, unexpected crisis, terrorism, changes on weather conditions, commercial behavior of competitors at the market etc. In this study, new heuristic approach for ensemble methodology has been proved. It has been implemented in SOK Market. It is one of Turkey's hard discount retail chain with 4000 stores and replenishes 1500 SKUs to stores via 22 regional distribution centers. The results of this approach and how to take benefits of the powerful common minded demand forecasting in time series forecasting analysis have been showed.
Reduction and oxidation of annulenes (1984)

ADVERTISEMENT RETURN TO ISSUEPREVArticleReduction and oxidation of annulenesKlaus MuellenCite this: Chem. Rev. 1984, 84, 6, 603–646Publication Date (Print):December 1, 1984Publication History Published online1 May 2002Published inissue 1 December 1984https://pubs.acs.org/doi/10.1021/cr00064a006https://doi.org/10.1021/cr00064a006research-articleACS PublicationsRequest reuse permissionsArticle Views618Altmetric-Citations121LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Synthesis of 6-Phenanthridinones and Their Heterocyclic Analogues through Palladium-Catalyzed Sequential Aryl−Aryl and <i>N</i>-Aryl Coupling (2004)

[reaction: see text] 6-Phenanthridinones and their heterocyclic analogues were synthesized through a one-pot procedure based on consecutive Pd-catalyzed aryl-aryl and N-aryl coupling from iodoarenes ortho-substituted by electron-releasing substituents and amides of o-bromoarene- and heteroarenecarboxylic acids.
Innovation in Teacher Preparation: - Using Performance Expectations and Annotated Video to Facilitate Reflection. (2016)

CalStateTEACH (CST) is a California State University statewide, online, site-supported teacher preparation program that prepares candidates primarily for teaching in elementary school. Teacher candidates engage in academic work online and participate in field experiences at a local school each term. The program promotes innovation, technology integration, and reflection (Mishra, Koehler, & Henrikson, 2011) via the Observation Event (OE) in the clinical practice component of the program. Data collected over three terms in the program is used to monitor candidate progress. The OE is a lesson planning interface that was developed to give teacher candidates greater control over the classroom observation process by determining the lesson focus and pedagogical proficiency levels based on California Teaching Performance Expectations (TPE) (California Commission for Teacher Credentialing [CCTC], 2013). The 13 TPEs are skills a teacher candidate needs to develop by the end of a teachertraining program. These are grouped within the broad range of categories in the Standards for the Teaching Profession: Making Subject Matter Comprehensible to Learners, Assessing Student Learning, Engaging and Supporting Students in Learning, Planning Instruction and Designing Learning Experiences for Students, and Creating and Maintaining Effective Environments for Student Learning (CCTC, 2009). See Figure 1. Candidates begin preparing for the OE by completing a lesson plan and choosing two or three TPEs indicating which aspects of teaching they intend to demonstrate, providing a rationale for that expectation. The elements of the electronic lesson plan include a preconference self-evaluation rationale for proficiency level performance and a reflective video feedback loop for teacher candidates. In the preconference self-evaluation, candidates rank their pedagogical proficiency levels for the TPEs by selecting exploring, applying, proficient, or exemplary, and providing a rationale for the ranking. Faculty mentors provide feedback to the candidate on the lesson plan prior to observing the lesson.
Performance evaluation of half-bridge cascaded multilevel converters operated with multicarrier sinusoidal PWM techniques (2009)

High-power high-voltage power electronics systems with fully-controlled semiconductors can benefit from the development of modular solutions based on voltage-sourced building blocks. This paper offers a performance comparison of various multicarrier sinusoidal pulse width modulation (PWM) techniques for the control of the modular multilevel converter (MMC) based on the half-bridge capacitor cell. It is found that the PWM method can significantly affect the ripple of the capacitor free DC-bus, hence the selection of the carrier frequency and the multi-carrier PWM method is an important design question for the MMC topology. Simulation results for a three-phase rectifier-inverter system generated with the PSCAD/EMTDC software package are provided to support the theoretical considerations.
The Effect of Dydrogesterone on Premenstrual Symptoms:<i>A Double-blind, Randomized, Placebo-controlled Study in General Practice</i> (1988)

The effect of dydrogesterone on premenstrual symptoms was investigated in a double-blind, randomized, placebo-controlled study comprising 161 patients from unselected practice material. Dydrogesterone 10 mg twice daily from the 12th day until onset of the following menstrual period was compared with placebo throughout 3 cycles. No clinically relevant effect of dydrogesterone was found. There was an overall therapeutic effect in 52% of the patients on dydrogesterone, and in 44% of the placebo-treated patients. Therapeutic gain ranged between -7 and +23% (95% confidence limits). Type II error risk of failure to detect a therapeutic gain of 20% was 6%. A significant effect of dydrogesterone was found on decreased libido, and statistical significance was nearly achieved for the symptoms irritability and headache. The significant effect on libido can be attributed to mass significance.
COMPETITORS WANT TO GET A PIECE OF LIPITOR (2006)

RETURN TO ISSUEPREVNewsNEXTCOMPETITORS WANT TO GET A PIECE OF LIPITORBiocatalysis offers a variety of enantioselective routes to key chiral intermediates for the drugANN M. THAYERView Author Information C&EN HOUSTONCite this: Chem. Eng. News 2006, 84, 33, 26–27Publication Date (Print):August 14, 2006Publication History Published online14 November 2010Published inissue 14 August 2006https://pubs.acs.org/doi/10.1021/cen-v084n033.p026https://doi.org/10.1021/cen-v084n033.p026newsACS PublicationsCopyright © 2006 AMERICAN CHEMICAL SOCIETYArticle Views25Altmetric-Citations16LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options SUBJECTS:Biocatalysis Get e-Alerts
Optimum design for eddy current reduction in permanent magnet to prevent irreversible demagnetization (2007)

Irreversible demagnetization which occurs in permanent magnet (PM) due to high temperature is main issue in design of traction motor for hybrid electric vehicle. In order to prevent irreversible demagnetization, eddy current loss in PM should be minimized. This paper deals with the optimum design to reduce eddy current loss in PM. Indirect method is used to instead of direct calculation of eddy current loss which uses 3D transient magnetic field analysis. To estimate eddy current loss indirectly, magneto-static field analysis is employed and the obtained flux density variation in PM is used based on the fact that eddy current loss is proportional to square of flux density and frequency. Response surface methodology coupled with design of experiment is used for optimum design in the objective function of peak-peak value and total harmonic distortion of flux density variation in PM Motor design process ensuring minimum variation of flux density in PM is presented and a transient analysis is used for verification of optimum design.
고령자들의 심혈관계 질환 위험 요소와 운동참여 여부가 심혈관계 위험 요인, 건강도, 운동능력, 성인병 발병률 및 사망률에 미치는 영향 (2004)

김남익. 고령자들의 심혈관계 질환 위험 요소와 운동참여 여부가 심혈관계 위험 요인, 건강도, 운동능력, 성인병 발병률 및 사망률에 미치는 영향. 운동과학, 제13권 제2호, 151-166, 2004. 본 연구는 심혈관계 질환 위험요소와 운동 참여 여부가 10년 전과 후인 현재, 남여고령자들에 있어서 심혈관계 위험 요인, 건강도, 운동능력, 성인병의 발병률과 사망률 분포에 미치는 영향을 규명하는데 연구의 목적이 있다. 연구대상은 총 111명(남 55, 여 56)으로 운동 집단, 비활동 집단, CVD + 운동 집단, CVD + 비활동 집단으로 구분하여 심혈관계 위험 요인, 혈액검사, 신체구성, 폐기능, 심박수, 혈압, 산소소비량, 운동시간, 성인병 발병률 및 사망률을 측정하였다. 연구결과에 있어서, CVD 위험 요인은 남자가 심장기능, 여자는 체지방이 유의하게 추출되었다. 건강도 및 운동능력 평가는 운동 집단과 CVD + 운동 집단이 운동에 참여하지 않는 집단에 비해 우수한 결과를 보였으며, 질환 보유자라도 운동참여가 성인병으로의 발병율을 지연시키는 것으로 나타났다. 성인병의 발병률은 운동 참여 집단에 비해 심혈관계 질환이나 비활동집단이 높았으며, 발병 원인에 있어서는 혈청지질이 다른 질환에 비해 가장 빈도가 높았다. 사망률은 운동 참여 집단에 비해 비활동 집단이 높았고, 사망 원인으로 심장병이 높았으며, 사망자들의 생활습관 및 운동습관은 가족력, 카페인 섭취, 활동 정도가 유의성이 있는 것으로 나타났다. 결론적으로, 고령자들은 심전도 이상이나 혈압, 체지방률이 높으면, 성인병의 합병증과 함께 수명에 영향을 미칠 수 있는 것을 알 수 있다.
Amino Acid Contacts between Sigma 70 Domain 4 and the Transcription Activators RhaS and RhaR (2004)

The RhaS and RhaR proteins are transcription activators that respond to the availability of L-rhamnose and activate transcription of the operons in the Escherichia coli L-rhamnose catabolic regulon. RhaR activates transcription of rhaSR, and RhaS activates transcription of the operon that encodes the L-rhamnose catabolic enzymes, rhaBAD, as well as the operon that encodes the L-rhamnose transport protein, rhaT. RhaS is 30% identical to RhaR at the amino acid level, and both are members of the AraC/XylS family of transcription activators. The RhaS and RhaR binding sites overlap the -35 hexamers of the promoters they regulate, suggesting they may contact the sigma70 subunit of RNA polymerase as part of their mechanisms of transcription activation. In support of this hypothesis, our lab previously identified an interaction between RhaS residue D241 and sigma70 residue R599. In the present study, we first identified two positively charged amino acids in sigma70, K593 and R599, and three negatively charged amino acids in RhaR, D276, E284, and D285, that were important for RhaR-mediated transcription activation of the rhaSR operon. Using a genetic loss-of-contact approach we have obtained evidence for a specific contact between RhaR D276 and sigma70 R599. Finally, previous results from our lab separately showed that RhaS D250A and sigma70 K593A were defective at the rhaBAD promoter. Our genetic loss-of-contact analysis of these residues indicates that they identify a second site of contact between RhaS and sigma70.
Astaxanthin inhibits apoptosis in alveolar epithelial cells type <scp>II </scp><i>in vivo and in vitro</i> through the <scp>ROS</scp>‐dependent mitochondrial signalling pathway (2014)

Oxidative stress is an important molecular mechanism underlying lung fibrosis. The mitochondrion is a major organelle for oxidative stress in cells. Therefore, blocking the mitochondrial signalling pathway may be the best therapeutic manoeuver to ameliorate lung fibrosis. Astaxanthin (AST) is an excellent antioxidant, but no study has addressed the pathway of AST against pulmonary oxidative stress and free radicals by the mitochondrion-mediated signalling pathway. In this study, we investigated the antioxidative effects of AST against H2 O2 - or bleomycin (BLM)-induced mitochondrial dysfunction and reactive oxygen species (ROS) production in alveolar epithelial cells type II (AECs-II) in vivo and in vitro. Our data show that AST blocks H2 O2 - or BLM-induced ROS generation and dose-dependent apoptosis in AECs-II, as characterized by changes in cell and mitochondria morphology, translocation of apoptotic proteins, inhibition of cytochrome c (Cyt c) release, and the activation of caspase-9, caspase-3, Nrf-2 and other cytoprotective genes. These data suggest that AST inhibits apoptosis in AECs-II cells through the ROS-dependent mitochondrial signalling pathway and may be of potential therapeutic value in lung fibrosis treatment.