gebhart/patrepeval huggingface dataset:
Interferon aplha-2b and hydroxocobalamine in epidemic neuropathy (1995)

More than 40 000 cases of an epidemic neuropathy were reported in Cuba during 1993. Trial tested the combination of IFN alpha-2b and hydroxocobalamine. The rationale of its use in the epidemic neuropathy is based on the toxic hypothesis of the origin of the disease.
ChemInform Abstract: New Bellenamine Homologues Inhibiting Human Immunodeficiency Virus Type 1 Infectivity. (1996)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Ochratoxin A in Cow’s Milk and in Human Milk with Corresponding Human Blood Samples (1993)

A method for determining ochratoxin A in milk has been elaborated in which the sample was subjected to a liquid-liquid extraction step and then purified on a silica gel column packed in a Pasteur pipet. The purified samples were analyzed by ion-pair liquid chromatography with fluorescence detection. The detection and quantitation limits for determination of ochratoxin A in cow's milk were 10 and 40 ng ochratoxin A/L milk, respectively. The same limits were valid for the analysis of human milk. A total of 36 cow's milk and 40 human milk samples were analyzed. All samples were collected in Sweden. Ochratoxin A was found in 5 (14%) of the cow's milk samples (range 10-40 ng/mL) and in 23 (58%) of the human milk samples (range 10-40 ng/L). Blood samples were collected from the mothers who gave milk samples. A total of 39 samples were analyzed. All blood samples contained ochratoxin A in concentrations exceeding the quantitation limit (60 ng/L blood). The mean concentration of ochratoxin A in the samples was 167 ng/L blood (range 90-940 ng/L). The concentration of ochratoxin A in human milk was < or = 0.1 of that in the human blood.
Tritium labelling of ribonuclease by the gas‐exposure method, as improved by an electric discharge (1976)

Abstract When lyophilized samples of bovine pancreatic ribonuclease are exposed to tritium gas, the exchange process can be markedly improved by applying high frequency electric discharges. Labelling has been carried out for 5, 15 or 30 minutes periods. Labile radioactivity, was then removed by means of molecular sieving and repeated lyophilizations, the tritiated protein being submitted to further purification by ion‐exchange chromatography. The specific radioactivity of such purified samples is in the Curie/mmole range, and the biological activity of the enzyme remains well preserved. The distribution of tritium atoms among component aminoacids has been determined, after acid hydrolysis of the labelled protein.
A FPGA-based Parallel Architecture for Scalable High-Speed Packet Classification (2009)

Multi-field packet classification is a critical function that enables network routers to support a variety of applications such as firewall processing, quality of service differentiation, traffic billing, and other value added services. Explosive growth of Internet traffic requires the future packet classifiers be implemented in hardware. However, most of the existing packet classification algorithms need large amount of memory, which inhibits efficient hardware implementations. This paper exploits the modern FPGA technology and presents a partitioning-based parallel architecture for scalable and high-speed packet classification. We propose a coarse-grained independent sets algorithm and then combine it seamlessly with the cross-producting scheme. After partitioning the original rule set into several coarse-grained independent sets and applying the cross-producting scheme for the remaining rules, the memory requirement is dramatically reduced. Our FPGA implementation results show that our architecture can store 10 K real-life rules in a single state-of-the-art FPGA while consuming a small amount of on-chip resources. Post place and route results show that the design sustains 90 Gbps throughput for minimum size (40 bytes) packets, which is more than twice the current backbone network link rate.
Synthesis of Mononuclear Non-Heme Iron(III)-Hydroperoxo Complex as an Oxidative Catalyst (2006)

Mononuclear FeII complex [FeII(ppba)]2+ (ppba = (6-pivalamido-2-pyridylmethyl) (2-pyridylmethyl)tert-butylamine) (1) has been synthesized and structurally characterized. The addition of H2O2 (10eq) to an acetone solution of 1 at -78°C generated FeIIIPPBA-OOH species, accompanied by a color change from pale yellow to reddish purple, which showed an intense absorption band corresponding to LMCT band (HOO- to Fe) at 528 nm (ε = 1120 M-1cm-1). The ESR spectrum for FeIIIPPBA-OOH species (g// = 4.22, g⊥ = 7.70 in acetone at 77 K) was typical of a high-spin FeIII species, suggesting that the FeIIIPPBA-OOH species is maintained as a mononuclear complex in the solution state. The resonance Raman spectra, when H2 16O2 and H2 18O2 were used, exhibited intense bands characteristic to the O-O stretching vibrations at 880 cm-1 ν(16O-16O) and 824 cm-1 ν(18O-18O), respectively. These findings suggest that FeIIIPPBA-OOH species is [FeIII(ppba)(OOH)]2+ (2). In order to understand the catalytic reactivity of complex 2, oxidative reactions for some organic substrates by complex 2 were carried out in the presence of H2O2; thioanisole was oxidized to the corresponding sulfoxide and sulfone, respectively, and furthermore, cyclohexene was converted to cyclohexene oxide, cyclohexenol and cyclohexenone.
Monogalactosyldiacylglycerol Confers Fusogenicity to Liposomal Delivery Systems and Facilitates Targeting to Hepatocytes (1999)

Fusogenic liposomes typically rely on unsaturated phosphatidyleth-anolamines, usually dioleoylphosphatidylethanolamine (DOPE), to confer the ability to fuse with cell membranes and deliver drug intracellularly. Targeted fusogenic liposomes require an additional component to facilitate binding to, and internalization within, specific cell populations. This report examines the ability of the unsaturated galactolipid monogalactosyldiacylglycerol (MGDG) to replace DOPE in pH-sensitive fusogenic liposomes and to simultaneously confer enhanced binding to hepatocytes. Liposomes prepared using the pH-sensitive lipid N-succinylDOPE and either DOPE, MGDG or a non-fusogenic control galactolipid were compared for (i) propensity to undergo either pH-or calcium-induced membrane fusion; (ii) ability to deliver encapsulated gen-tamicin to infections of Salmonella typhimurium in murine macrophages; and (iii) binding and uptake into human hepatoma cells. Liposomes composed of MGDG/N-succinylDOPE were very similar to those of DOPE/N-succinyl-DOPE for both the fusion rate and final extent of fusion induced by lowered pH. In contrast, MGDG/N-succinylDOPE liposomes were substantially less susceptible than DOPE/N-succinylDOPE liposomes to fusion at physiological pH induced by addition of calcium. The ability of the MGDG/N-succinylDOPE formulation to deliver the membrane-impermeable antibiotic gentami-cin to infections of S. typhimurium in macrophages was equal or superior to that achieved by the DOPE/N-succinylDOPE preparation. The binding and uptake of MGDG/N-succinylDOPE liposomes into HepG2 hepatoma cells was 3.5-fold greater than that of the DOPE/N-succinylDOPE formulation and 7.6-fold greater than that of a galactolipid control preparation. Taken together, these data demonstrate the potential to achieve both fusogenicity and hepato-cyte targeting by the addition of a single component, MGDG, to liposomal drug delivery systems.
Expression of human leukotriene A<sub>4</sub> hydrolase cDNA in <i>Escherichia coli</i> (1988)

The cDNA clone encoding human leukotriene A4 hydrolase was inserted into a vector pUC9 and expressed in Escherichia coli as a fusion protein containing the first 10 amino acid residues derived from a vector. The leukotriene A4 hydrolase activity was recovered in the soluble fraction of the transformants. The purified enzyme showed kinetic properties similar to the native enzyme, including inactivation by the substrate and sulfhydryl-modifying reagents. The results demonstrate that a protein with an Mr of 70,000 was expressed in Escherichia coli with a full enzyme activity and structural fidelity. Acquisition of the expression system makes it feasible to elucidate the reaction mechanism of the enzyme.
Sustainable Operation of Arterial Networks (2017)

This report describes operational data analysis and modeling of arterial networks with signalized intersections as follows: The setup for data collection, analysis and simulation is presented in Section 2.1. Detailed analysis of collected signal phasing and traffic data is provided in section 2.2. Arterial traffic and platoon modeling is described in Section 2.3. Simulation results of the Rollins Park network is discussed in Section 2.4. Research conducted under this task is an important stepping stone for building a three-level information and control system for urban networks with high-density traffic. In this task researchers focused on elements of link-level information (signal phasing and timing (SPaT) estimation and prediction) and vehicle-level control (Adaptive Cruise Control (ACC) and Cooperative Adaptive Cruise Control (CACC)). In SPaT analysis researchers presented several novel algorithms to estimate the residual duration of a signal phase for a semi-actuated intersection. These algorithms predict the times for all future phase transitions, based on previous phase measurements and on the real time information that locates the current time within the current phase. With respect to the vehicle-level control, researchers analyzed sensitivity of intersection throughput to car following models and related parameters. The Improved Intelligent Driver Model (IIDM) was chosen for traffic simulation. Finally, researchers implemented the platoon model in Simulation of Urban MObility (SUMO) and tested it in simulation of scenarios on Rollins Park network.
Convergence-Accommodation Relationships (1960)

<h3>Introduction</h3> The purpose of this study is first to describe a simple test for studying the relationship between the stimulus to accommodation and the accommodative convergence at a fixed near distance, and second to illustrate by case reports the value of graphic analyses of this relationship in classifying oculomotor anomalies and in evaluating various forms of therapy. <h3>Previous Investigations</h3> The ophthalmological literature of 50 or more years ago includes papers describing the use of graphs to depict relationships between convergence and accommodation and amplitudes of relative fusional convergence and divergence. This early work has been reviewed by Morgan.<sup>1</sup> In recent years two simpler procedures have been used, particularly in research laboratories of physiological optics, to study the changes in convergence induced by changes in accommodation. In most cases only normal subjects without ocular symptoms have been studied. The two procedures may be designated as the variable-distance method and the
Three‐Dimensional Geometry of Nanometer‐Scale AlN Pits: A New Template for Quantum Dots? (2007)

The exact 3D geometry of nanometer-scale AlN pits is determined by Z-contrast imaging. The figure shows the 3D geometry of an AlN nano-pit and its corresponding GaN quantum dot. An atomic-resolution Z-contrast image is displayed in false color to clearly show the Z-contrast of the image, while the other panel displays a schematic 3D view.
Praktische Hinweise (1991)

Die Einführung neuer Systeme zum Einsatz in Rechtsbeziehungen privater und geschäftlicher Art, die zuvor auf andere Weise abgewickelt wurden, wird stets nur dann gelingen, wenn mit einer umfassenden Akzeptanz der betroffenen Personenkreise gerechnet werden darf. In Bereichen, in denen es bereits bisher auf eine aussagekräftige Unterschrift ankam, vornehmlich also im Vertrags- und Zahlungsbereich, wird dies vor allem dann der Fall sein, wenn das neue System ebenso verläßlich erscheint wie bisherige Arbeitsweisen und mit der Einführung des neuen Verfahrens darüberhinaus gewisse Funktionen verbunden sind, die das bisherige Verfahren nicht bieten kann -kurz, wenn es Vorteile aufweist, die seine eventuell vorhandenen Nachteile (und sei es nur die Tatsache, daß man sich mit Neuerungen erst vertraut machen muß) jedenfalls überwiegen. Im folgenden sei daher die Betonung einiger notwendiger Punkte erlaubt, die dem Leser mitunter trivial anmuten mögen, deren Beachtung bei Einführung der elektronischen Unterschrift aber nach Auffassung der Verfasser nicht übersehen werden sollte.
Consideration of the 'Burp' phenomenon in solid methane accounting for nonuniform distribution of irradiation defects (1997)

This paper focuses on an optional model of radical recombination in solid methane, apart from conventional theory. It shares the common property of two-order reactions, but accounts for local nonuniformitites of the objects involved (such as radical concentration, the track nature of energy deposition, and others). Accounting for local nonuniformity provides absolutely different results for the time dependence of the space-averaged concentration of radicals, both for the processes of their storage and 'burping', compared to the common approach; it also brings new conditions for the thermal instability of the methane slug under irradiation and gives a better understanding of most of the strange features of burp performances.
Tracking loop for fading dispersive channels (1990)

An optimum closed-loop symbol synchronizer operating over fading dispersive channels is developed. It is shown that the optimum tracking synchronizer is a multiplier that forms the product of the received signal and a filtered version of it, the filter impulse response is the first derivative with respect to time (or frequency) of the autocorrelation function of the signal part of the received waveform. It is proved that for small misalignment the control signal vector is an incrementally linear function of the error vector. For a Gaussian-shaped scattering function, a simple closed-loop structure is obtained and expressions for tracking error statistics are derived. The dependency of such statistics on the signal-to-noise ratio and on the spread of the channel is investigated.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Abstract 16167: A GWAS of EHR-Defined CAD Identifies Multiple Novel Loci Including the First 3 Loci on the X-Chromosome: The Million Veteran Program (2017)

Introduction: Genome wide association studies (GWAS) to date have identified 78 susceptibility loci for coronary artery disease (CAD). These loci explain a modest fraction of the heritability of CA...
ChemInform Abstract: Synthesis of the C‐Analogue of 2‐Acetylamino‐2‐deoxy‐β‐D‐glucopyranosyl L‐ and D‐Serine. (1998)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
COMPUTATIONAL AND EXPERIMENTAL MODELING OF SLURRY BUBBLE COLUMN REACTORS (2001)

This project is a collaborative effort between the University of Akron, Illinois Institute of Technology and two industries: UOP and Energy International. The tasks involve the development of transient two and three dimensional computer codes for slurry bubble column reactors, optimization, comparison to data, and measurement of input parameters, such as the viscosity and restitution coefficients. To understand turbulence, measurements were done in the riser with 530 micron glass beads using a PIV technique. This report summarizes the measurements and simulations completed as described in details in the attached paper, ''Computational and Experimental Modeling of Three-Phase Slurry-Bubble Column Reactor.'' The Particle Image Velocimetry method described elsewhere (Gidaspow and Huilin, 1996) was used to measure the axial and tangential velocities of the particles. This method was modified with the use of a rotating colored transparent disk. The velocity distributions obtained with this method shows that the distribution is close to Maxwellian. From the velocity measurements the normal and the shear stresses were computed. Also with the use of the CCD camera a technique was developed to measure the solids volume fraction. The granular temperature profile follows the solids volume fraction profile. As predicted by theory, the granular temperature is highest at the center of the tube. The normal stress in the direction of the flow is approximately 10 times larger than that in the tangential direction. The <{nu}{prime}{sub z}{nu}{prime}{sub z}> is lower at the center where the <{nu}{prime}{sub {theta}}{nu}{prime}{sub {theta}}> is higher at that point. The Reynolds shear stress was small, producing a restitution coefficient near unity. The normal Reynolds stress in the direction of flow is large due to the fact that it is produced by the large gradient of velocity in the direction of flow compared to the small gradient in the {theta} and r directions. The kinetic theory gives values of viscosity that agree with our previous measurements (Gidaspow, Wu and Mostofi, 1999). The values of viscosity obtained from pressure drop minus weight of bed measurements agree at the center of the tube.
Neural Network-Based Hyperspectral Algorithms (1999)

Abstract : The long-term goal of our effort is development of robust numerical inversion algorithms, which will retrieve inherent optical properties of the water column as well as depth, and bottom type information from remotely sensed hyperspectral data sets of littoral regions. We have two primary objectives; 1) using a combination of in-situ and model data of water column variables (IOP's, depth, bottom type, upwelling radiance, etc.) a neural network non-linear function approximation model will be used to establish the inverse relationship between upwelling surface radiance and the water column variables, 2) validate the resulting inversion algorithms with in-situ data and provide estimates of the error bounds associated with the inversion algorithm.
Template design and propagation gain for multipath UWB channels with per-path frequency-dependent distortion (2009)

Due to the large bandwidth allocation, Ultra-Wideband (UWB) channels exhibit frequency-dependent distortion of individual multipath components. This per-path distortion is particularly significant in outdoor UWB applications, where line-of-sight (LOS) or non-distorted reflected signals might not be available at the receiver, and the dominant propagation mechanisms involve shadowing (diffraction) or reflection by small objects (e.g. signs or lamp-posts). In this paper, a physical model is employed in the design of robust correlation receiver templates for outdoor single and multipath impulse radio channels characterized by per-path distortion. It is demonstrated that receivers which employ a set of partial derivatives templates are near-optimal in terms of energy capture while the simple transmit pulse template provides excellent complexity-performance trade-offs for most practical scenarios. Moreover, iterative receiver structures that maintain the energy capture in the presence of overlapping multipath components are investigated. Finally, a large gap between the propagation gains of the transmit pulses in the lower and upper bands of the FCC spectrum is characterized for several propagation mechanisms.
High-field Mössbauer studies of reduced protocatechuate 3,4-dioxygenase (1978)

We have studied the Mössbauer spectra of reduced protocatechuate 3,4-dioxygenase (3,4-PCase) from P. aeruginosa in the temperature range from 1.5 to 200 K in applied magnetic fields up to 55 kG. The entire data set was fitted to a spin Hamiltonian pertinent to the high-spin ferrous ion. By judiciously choosing the experimental conditions, the multiparameter problem could be solved rather unambigously. The iron sites of reduced 3,4-PCase are characterized by a negative zero-field splitting parameter D=−(6±1) cm−1 and a large rhombicity E/D=0.25±0.05. The data show clearly that the electric field gradient tensor is rotated relative to the zero-field splitting, suggesting a point symmetry of monoclinic or lower. The electronic spin relaxation rate, at 4.2 K, is slower than 107 s−1.
Targeting Epithelial-Mesenchymal Transition Phenotype for Gastro-Intestinal Cancer (2015)

Gastrointestinal (G-I) cancers are one of the most common malignant tumors worldwide. Symptoms relate to the organ affected in the G-I tract are non-specific, making early detection and effective treatment difficult to achieve. Epithelial-mesenchymal transition (EMT), a reversible and dynamical process, can disperse cells in embryos, form mesenchymal cells in injured tissues, and regulate embryonic stem cell differentiation. A variety of signaling molecules and distinct pathways are involved in the initiation and progression of EMT. Recent evidence has established that EMT may endow G-I cancer cells with the capacity to invade surrounding tissues, resist apoptosis, migrate to distant organs, and develop chemoresistance. Targeting these signaling molecules and pathways associated with EMT may provide clinicians with a new approach to the treatment of G-I malignancy.
Modeling and Measurement of H-Bot Kinematic Systems (2011)

INTRODUCTION Due to the ever increasing demand for high productivity which implies high dynamics at reduced costs additional efforts are required in the search for alternative structural designs. This leads to the permanent investigation of alternative machine concepts for the application in fields, where standard, serial concepts have been used so far. Even if alternative kinematics are already used as is the case of 3D pick and place applications, other parallel structures have to be studied in order to improve the system’s overall capabilities. In this paper a parallel kinematic structure called H-Bot has been investigated [1] and realized comprising modeling and measurement. The results of both areas of investigation are shown and discussed.
Test of a Power Transfer Model for Standardized Electrofishing (2003)

Abstract Standardization of electrofishing in waters with differing conductivities is critical when monitoring temporal and spatial differences in fish assemblages. We tested a model that can help improve the consistency of electrofishing by allowing control over the amount of power that is transferred to the fish. The primary objective was to verify, under controlled laboratory conditions, whether the model adequately described fish immobilization responses elicited with various electrical settings over a range of water conductivities. We found that the model accurately described empirical observations over conductivities ranging from 12 to 1,030 μS/cm for DC and various pulsed‐DC settings. Because the model requires knowledge of a fish's effective conductivity, an attribute that is likely to vary according to species, size, temperature, and other variables, a second objective was to gather available estimates of the effective conductivity of fish to examine the magnitude of variation and to assess whether in practical applications a standard effective conductivity value for fish may be assumed. We found that applying a standard fish effective conductivity of 115 μS/cm introduced relatively little error into the estimation of the peak power density required to immobilize fish with electrofishing. However, this standard was derived from few estimates of fish effective conductivity and a limited number of species; more estimates are needed to validate our working standard.
Premature Chromosome Condensation (PCC): Tools in chromosome and cytogenetic research (2013)

Deep insight on Premature Chromosome Condensation (PCC): Tools in chromosome and cytogenetic research.