gebhart/patrepeval huggingface dataset:
Effets de la maghémitisation des titanomagnétites sur les propriétés magnétiques des basaltes sous-marins : synthèse et résultats relatifs aux basaltes du Leg 51 (1983)

Les propriétés magnétiques des roches résultent essentiellement des effets combinés de la concentration, du chimisme et des dimensions de leurs minéraux magnétiques ; or ces effets s'interpénétrent dans le cas de la maghémitisation, car celle-ci entraîne systématiquement une diminution de la taille et éventuellement de la concentration des titanomagnétites. Les contradictions souvent observées dans les résultats antérieurs proviennent en partie de ce que les effets observés représentent en réalité la résultante des variations de ces trois paramètres. La présente étude tente de mettre en évidence les effets de la maghémitisation sur les propriétés magnétiques de basaltes d'âge Crétacé, indépendamment de la concentration et de la taille de leurs minéraux magnétiques. Les échantillons sont classés en deux groupes, selon la microstructure des minéraux magnétiques : les échantillons de «pillow » à grains essentiellement monodomaines (SD) et les échantillons d'«unité massive » à grains pseudomonodomaines (PSD) et polydomaines (MD). Les analyses thermomagnétiques et chimiques à la microsonde électronique montrent qu'indépendamment du type de roche, la composition chimique des titanomagnétites varie faiblement de 0,55 < x' < 0,65 et la teneur en éléments mineurs, Al et Mg, reste sensiblement constante. La plage des degrés d'oxydation est plus étendue et la maghémitisation généralement plus faible dans les échantillons d'unité massive (0,3 < z' < 0,9) que dans les pillows (0,7 < z' <1). Une fois mises en évidence, dans chacun des types de roche, les variations d'un échantillon à l'autre de la concentration et de la taille moyenne des titanomagnétites, les effets magnétiques de la maghémitisation peuvent se résumer comme suit. La maghémitisation entraîne une diminution régulière de l'aimantation spontanée, js, de la titanomagnétite et donc une décroissance de l'intensité de l'aimantation rémanente, Jr, de la roche. Bien qu'aucune variation claire de la susceptibilité ferrimagnétique, K, en fonction du degré d'oxydation ne ressorte des présents résultats, il semble que celle-ci augmente si les titanomagnétites ont des microstructures SD et diminue faiblement pour des grains MD. Inversement, la coercivité des grains SD diminue et celle des grains MD augmente avec la maghémitisation. Contrairement à toute attente, la viscosité magnétique des grains SD des pillows de cette étude reste négligeable, même lorsque l'oxydation est totale. La viscosité est toujours grande dans les unités massives mais aucune tendance n'apparaît. Il semble que la viscosité magnétique soit davantage contrôlée par la microstructure des minéraux magnétiques que par leur degré de maghémitisation.
Metropolitan area optical networks (2003)

Presented the requirements, architectures, and performance of optical MANs. We outlined our considerations about the evolution of metro area networks from SONET rings to transparent WDM rings. We also described the major transport impairments that the network designer should account for in transparent WDM MANs. A properly engineered network utilizing application-optimized components and fiber will enable the buildup of cost-effective metro/regional WDM optical networks that satisfy all the requirements and demands.
The role of cellular polysaccharides in the formation and stability of aerobic granules (2001)

It is expected that this study would provide useful information for better understanding the mechanisms of aerobic granulation.
Host defence peptides: antimicrobial and immunomodulatory activity and potential applications for tackling antibiotic-resistant infections (2009)

The rapidly increasing incidence of multidrug-resistant infections and the alarmingly low rate of discovery of conventional antibiotics create an urgent need for alternative strategies to treat bacterial infections. Host defence peptides are short cationic molecules produced by the immune systems of most multicellular organisms; they are a class of compounds being actively researched. In this review, we provide an overview of the antimicrobial and immunomodulatory activities of natural host defence peptides, and discuss strategies for creating artificial derivatives with improved biological and pharmacological properties, issues of microbial resistance, and challenges associated with their adaptation for clinical use. (Published: 24 February 2009)Citation: Emerging Health Threats Journal 2009, 2:e1.
The Effect of Silicone Oil on the Cornea (1985)

Intraocular silicone oil tamponade is being used with increasing frequency as an adjunct to conventional vitrectomy techniques in the treatment of proliferative vitreoretinopathy. When used in patients with aphakia, corneal decompensation is a common long-term complication. In this study, we evaluated the clinical and morphologic changes that occurred in the corneas of 14 rabbits and seven cats when the anterior chamber was filled with silicone oil. Within six days, wide-field specular microscopy showed a 40% reduction in endothelial density in the area of the silicone oil bubble in both groups. Progressive stromal thinning occurred in the rabbit cornea, with gradual development of a retrocorneal membrane at the junction of silicone-endothelial cell contact. In contrast, persistent stromal edema, peripheral vascularization, irregular plaques on the endothelium, and eventual epithelial ulceration and corneal thinning occurred in cat eyes.
The Roles of the Prosequence of Thermolysin in Enzyme Inhibition and Folding in Vitro (1996)

The zinc endopeptidase thermolysin (EC 3.4.24.27), an extracellular enzyme from Bacillus thermoproteolyticus, is synthesized as a preproprotein, with the prosequence (204 residues) being two-thirds the size of the mature enzyme (316 residues). This prosequence, expressed in and purified from Escherichia coli, inhibited thermolysin in vitro with an IC50 value of 14 nM. It also inhibited a closely related enzyme produced by Bacillus stearothermophillus, albeit with a 16-fold higher IC50 value (220 nM). The IC50 value for thermolysin inhibition was also increased 15-fold (210 nm) by a monoclonal antibody that recognizes an epitope close to, but not forming a part of, the active site. At a prosequence concentration of 5 microM a mammalian, thermolysin-like enzyme, neutral endopeptidase 24.11, was not inhibited. The prosequence appeared to act as a mixed, noncompetitive inhibitor of thermolysin activity, with a Ki value of 6 nM for its interaction with the enzyme alone and a Ki' value of 20 nM for its interaction with the enzyme-substrate complex. In addition, when thermolysin was denatured in 6 M guanidinium hydrochloride at acid pH and then brought to neutral pH by rapid dilution, the prosequence was found to facilitate the recovery of active enzyme in a stoichiometric manner.
An Improved Multi-Dimensional Storage Structure for Data Warehousing (2002)

As for physical data organization in data warehouse, there are mainly two kinds of methods, relational and multi-dimensional. These two methods have their own advantages and disadvantages, but as to improve the performance of OLAP (online analytical processing) query processing, the method of multi-dimensional array is superior. To solve the current problems in the method of multi-dimensional array, an improved multi-dimensional storage structure for data warehouse is proposed, and the concepts of logical storage and physical storage for data cube are given. According to this proposal, the original multi-dimensional data space is divided into many logical blocks, and a logical block is divided into many physical blocks. This multi-dimensional storage structure takes the characteristics of the large amount and highly sparse multi-dimensional array into consideration fully, and a new distributing and compressing method for the multi-dimensional array is adopted. These methods availably solve some efficiency problems of the aggregation query along with the inner level of the dimension and cube query, and dramatically improve the response time of the aggregation query. In particular, these methods also bring additional b9enefit for incremental maintenance of the multi-dimensional array.
Rough Set Approach for Group Evacuation Behavior Analysis in Passenger Transport Hub Area (2014)

Evacuation behavior analysis is deemed to be one aspect of evacuation planning. However, existing studies have not discussed group evacuation decision-making in the face of disagreement among decision makers. In this paper, rough set theory is applied to analyze group evacuation decision-making in passenger transport hub area with various groups including kin, lover, friend, colleague, and classmate. In the approach, improved tabu search-based attribute reduction is proposed to find the minimal subset of attributes required to fully describe the information of group evacuation decision-making, and value reduction algorithm based on knowledge granulation is used to generate rules of group evacuation decision-making. Cross-validation procedure is adopted to estimate the performance of rough set theory. Experimental results indicate that rough set theory has favorable performance. Thus, the proposed approach provides a new way for evacuation behavior analysis.
Long-term results of stem cell transplantation for MS (2011)

This study provides Class IV evidence that HSCT results in PFS rates of 25%. PFS rate was significantly better in patients with active MRI lesions; HSCT also resulted in a significant reduction in the number and volume of gadolinium-enhancing lesions on MRI.
Formation and hydrolysis of lactones of phenolic acids (1980)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTFormation and hydrolysis of lactones of phenolic acidsMichael Caswell and Gaston L. SchmirCite this: J. Am. Chem. Soc. 1980, 102, 14, 4815–4821Publication Date (Print):July 1, 1980Publication History Published online1 May 2002Published inissue 1 July 1980https://pubs.acs.org/doi/10.1021/ja00534a041https://doi.org/10.1021/ja00534a041research-articleACS PublicationsRequest reuse permissionsArticle Views889Altmetric-Citations36LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
Caffeine and Adenosine (2010)

Caffeine causes most of its biological effects via antagonizing all types of adenosine receptors (ARs): A1, A2A, A3, and A2B and, as does adenosine, exerts effects on neurons and glial cells of all brain areas. In consequence, caffeine, when acting as an AR antagonist, is doing the opposite of activation of adenosine receptors due to removal of endogenous adenosinergic tonus. Besides AR antagonism, xanthines, including caffeine, have other biological actions: they inhibit phosphodiesterases (PDEs) (e.g., PDE1, PDE4, PDE5), promote calcium release from intracellular stores, and interfere with GABA-A receptors. Caffeine, through antagonism of ARs, affects brain functions such as sleep, cognition, learning, and memory, and modifies brain dysfunctions and diseases: Alzheimer's disease, Parkinson's disease, Huntington's disease, Epilepsy, Pain/Migraine, Depression, Schizophrenia. In conclusion, targeting approaches that involve ARs will enhance the possibilities to correct brain dysfunctions, via the universally consumed substance that is caffeine.
Experimental study of a high blocking voltage power MOSFET with integrated input amplifier (1983)

Using a slight modification of the SIPMOS® (Siemens Power MOS) technology an integrated test structure has been realized containing a vertical power MOS transistor and an input amplifier. The input amplifier, hich greatly reduces the input capacitance, consists of a vertical n-channel transistor and a lateral p-channel transistor. By this way short switching times are possible even with high-ohmic drivers.
A class of active-RC filters with predictive characteristics (2002)

A class of analog continuous-time filters is introduced, having predictive properties for specified narrow-band signal models, such as low-order polynomials or sinusoids. Such filters are designed by using model transfer functions designed in the discrete-time domain. 2- to s-domain mapping is done using the inverse bilinear transformation. Predictive analog filters are implemented using active-RC structures. Several examples of constructed and measured prototypes are given, using the state-variable structure for biquads, and a single-op-amp structure for real poles and zeros.
Advanced Simulation of Droplet Microfluidics (2019)

The complexity of droplet microfluidics grows with the implementation of parallel processes and multiple functionalities on a single device. This poses a severe challenge to the engineer designing the corresponding microfluidic networks. In today’s design processes, the engineer relies on calculations, assumptions, simplifications, as well as his/her experiences and intuitions. To validate the obtained specification of the microfluidic network, usually a prototype is fabricated and physical experiments are conducted thus far. In case the design does not implement the desired functionality, this prototyping iteration is repeated—obviously resulting in an expensive and time-consuming design process. To avoid unnecessary debugging loops involving fabrication and testing, simulation methods could help to initially validate the specification of the microfluidic network before any prototype is fabricated. However, state-of-the-art simulation tools come with severe limitations, which prevent their utilization for practically relevant applications. More precisely, they are often not dedicated to droplet microfluidics, cannot handle the required physical phenomena, are not publicly available, and can hardly be extended. In this work, we present an advanced simulation approach for droplet microfluidics that addresses these shortcomings and, eventually, allows simulating practically relevant applications. To this end, we propose a simulation framework at the one-dimensional analysis model, which directly works on the specification of the design, supports essential physical phenomena, is publicly available, and is easy to extend. Evaluations and case studies demonstrate the benefits of the proposed simulator: While current state-of-the-art tools were not applicable for practically relevant microfluidic networks, the proposed simulator allows reducing the design time and costs, e.g., of a drug screening device from one person month and USD 1200, respectively, to just a fraction of that.
Data-aided frequency estimation for PSK signaling in frequency-selective fading (2001)

A new data-aided frequency estimator is introduced for phase-shift keying signals transmitted over frequency-selective fading channels. This estimator is developed based on a maximum likelihood criterion. It assumes the use of a special class of pilots, called near-i.i.d. (independent identically distributed) sequences, with impulsive fourth-order moments. With the help of such pilots, the proposed method can estimate frequency offsets without the need for channel information. The pilots of GSM and IS-136 mobile communication systems have been observed as being near-i.i.d., and statistical analysis indicates that the proposed estimate is almost unbiased if the pilot is near-i.i.d. The advantage of the proposed estimator over conventional methods is demonstrated via computer simulation.
77. von Braun's “diphenylcyclobutane derivative”: 6,6′-di-hydroxy-3,3,3′,3′-tertramethyl-1,1′-spirobi-indane and a related compound (1962)

R. F. Curtis, J. Chem. Soc., 1962, 415 DOI: 10.1039/JR9620000415
Preparation and reaction of tert-butyl trimethylsilyl carbonate and related compounds (1971)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPreparation and reaction of tert-butyl trimethylsilyl carbonate and related compoundsD. Stanley Tarbell and Yasusi YamamotoCite this: J. Org. Chem. 1971, 36, 20, 2954–2956Publication Date (Print):October 1, 1971Publication History Published online1 May 2002Published inissue 1 October 1971https://pubs.acs.org/doi/10.1021/jo00819a010https://doi.org/10.1021/jo00819a010research-articleACS PublicationsRequest reuse permissionsArticle Views373Altmetric-Citations14LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Methods for the Evaluation of Responses to Estrogen in Individual Cell Types or Regions of the Uterus (1984)

Nongenomic responses to estrogen and the genomic responses in the different uterine cell types can be dissociated selectively. The present report describes morphometric methods for the evaluation of estrogen-induced uterine edema and of genomic responses in individual cell types. The morphometric measurements of the genomic responses correlated with a classically accepted biochemical method of genomic response evaluation in the uterus (increase in RNA/DNA). Edema correlated with the classically accepted method of evaluation of uterine water imbibition, i.e., estrogen-induced increase in uterine wet weight 6 h after hormone administration.
Enzymatic addition of fluorescein- or biotin-riboUTP to oligonucleotides results in primers suitable for DNA sequencing and PCR. (1993)

An enzymatic, post-synthetic, non-isotopic modification of oligonucleotides giving primers that are substrates for chain elongation by DNA polymerases is described. It is shown that terminal deoxynucleotidyl transferase incorporates preferentially and almost exclusively a single fluorescein- or biotin-riboUTP at the 3' terminus of oligonucleotides. This one-step procedure, using readily available materials, permits an economical enzymatic labeling of oligonucleotides designed for fluorescence-based or solid-state DNA sequencing or PCR and offers a convenient alternative to chemical modification.
Large‐scale neurocognitive networks and distributed processing for attention, language, and memory (1990)

Cognition and comportment are subserved by interconnected neural networks that allow high-level computational architectures including parallel distributed processing. Cognitive problems are not resolved by a sequential and hierarchical progression toward predetermined goals but instead by a simultaneous and interactive consideration of multiple possibilities and constraints until a satisfactory fit is achieved. The resultant texture of mental activity is characterized by almost infinite richness and flexibility. According to this model, complex behavior is mapped at the level of multifocal neural systems rather than specific anatomical sites, giving rise to brain-behavior relationships that are both localized and distributed. Each network contains anatomically addressed channels for transferring information content and chemically addressed pathways for modulating behavioral tone. This approach provides a blueprint for reexploring the neurological foundations of attention, language, memory, and frontal lobe function.
Rates of removal and degradation of chylomicron remnants by isolated perfused rat liver. (1978)

Chylomicron remnants are removed intact by isolated perfused rat livers and their lipid components are metabolized by the liver (Biochim. Biophys. Acta 488: 464, 1977). The present study provides quantitative information regarding these processes. When the lipoprotein concentration of the perfusate was constant, the removal of chylomicron remnants increases lineraly for 17 min. The rate of remnant removal was a hyperbolic function of the perfusate's remnant concentration. The removal rate had aV max of 28microgram cholesterol per g liver per min and an apparent Km of 64 microgram cholesterol per ml perfusate. Feeding the liver donors a diet containing 1% cholesterol or 4% cholesterol and 1% cholic acid failed to alter the hepatic removal rate. The cholesteryl ester removed from the remnants was hydrolyzed at a rate that was a small fraction of the removal rate (about 0.5% of removed cholesteryl ester per min). The rate of cholesteryl ester hydrolysis did not appear to approach saturation in the range studied. Studies of the lysosomal cholesteryl ester hydrolase suggested that this enzyme was not responsible for limiting the initial rate of hydrolysis, raising the possibility that the degradation rate is determined by the movement of the removed remnant to the site of hydrolysis.
Technical Challenges for Wireless Instrument Networks - A Case Study with ZigBee (2007)

In this paper, the critical aspects of wireless instrument networks including energy efficiency, transmission range, radio frequency interference, packet error rate, and self healing capability have been discussed. An instrument network based on ZigBee has been set up for investigations. The network had a transmission range of up to 120 meters between the nodes under line-of-sight conditions. The range could be extended by multi-hop operations and utilizing self healing capabilities of the network. It is found that ZigBee based instrument networks are robust but susceptible to interference from other networks operating at the same ISM frequency band, such as WiFi and Bluetooth.
THE RELATION BETWEEN MUSIC AND PHONOLOGICAL PROCESSING IN NORMAL-READING CHILDREN AND CHILDREN WITH DYSLEXIA (2008)

PAST RESEARCH HAS SHOWN THAT MUSIC and language skills are related in normal-reading children as well as in children with dyslexia. In both an ongoing longitudinal study with normal-reading children and a pilot study with children with dyslexia, we found a strong relationship between musical discrimination abilities and language-related skills. In normal-reading children, musical discrimination predicted phonological and reading skills (Studies 1 and 2). These relationships were stronger in children with music training than in control children without music training. In children with dyslexia,musical discrimination predicted phonological skills, which in turn predicted reading abilities (Study 3). Furthermore, normal-reading children with music training surpassed both normal-reading controls and children with dyslexia in melodic discrimination. Controls also outperformed children with dyslexia (Study 4). Taken together, these findings suggest that a music intervention that strengthens the basic auditory music perception skills of children with dyslexia may also remediate some of their language deficits.