gebhart/patrepeval huggingface dataset:
Pressure dependence of associative substitution reactions of (dicarbonyl)(cyclopentadienyl)rhodium (1991)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPressure dependence of associative substitution reactions of (dicarbonyl)(cyclopentadienyl)rhodiumP. Vest, J. Anhaus, H. C. Bajaj, and Rudi. Van EldikCite this: Organometallics 1991, 10, 3, 818–819Publication Date (Print):March 27, 1991Publication History Published online1 May 2002Published inissue 27 March 1991https://pubs.acs.org/doi/10.1021/om00049a053https://doi.org/10.1021/om00049a053research-articleACS PublicationsRequest reuse permissionsArticle Views73Altmetric-Citations18LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Imaging topography and viscoelastic properties by constant depth atomic force microscopy (2016)

Identification of mechanical properties of cells is known to be an effective tool for medical diagnosis, and holds potential for future developments in treatment of various diseases. In this paper a novel method for identification of viscoelastic properties of a soft sample using atomic force microscopy in dynamic mode is presented. The estimation scheme is based on parameter identification of a lumped spring-damper system model. The estimator guarantees exponentially fast parameter convergence. The indentation depth of the tip into the sample must be constant for viscoelastic properties to be consistent during a scan. A depth controller is designed to keep the indentation constant by utilizing the online estimates of the sample spring constant and topography. Simulations show the effectiveness of the presented method.
SU-E-T-142: Effect of the Bone Heterogeneity On the Unflattened and Flattened Photon Beam Dosimetry: A Monte Carlo Comparison (2014)

Purpose: This study compared the dependence of depth dose on bone heterogeneity of unflattened photon beams to that of flattened beams. Monte Carlo simulations (the EGSnrc-based codes) were used to calculate depth doses in phantom with a bone layer in the buildup region of the 6 MV photon beams. Methods: Heterogeneous phantom containing a bone layer of 2 cm thick at a depth of 1 cm in water was irradiated by the unflattened and flattened 6 MV photon beams (field size = 10×10 cm2). Phase-space files of the photon beams based on the Varian TrueBeam linac were generated by the Geant4 and BEAMnrc codes, and verified by measurements. Depth doses were calculated using the DOSXYZnrc code with beam angles set to 0° and 30°. For dosimetric comparison, the above simulations were repeated in a water phantom using the same beam geometry with the bone layer replaced by water. Results: Our results showed that the beam output of unflattened photon beams was about 2.1 times larger than the flattened beams in water. Comparing the water phantom to the bone phantom, larger doses were found in water above and below the bone layer for both the unflattened and flattened photon beams. When both beams were turned 30°, the deviation of depth dose between the bone and water phantom became larger compared to that with beam angle equal to 0°. Dose ratio of the unflattened and flattened photon beams showed that the unflattened beam has larger depth dose in the buildup region compared to the flattened beam. Conclusion: Although the unflattened photon beam had different beam output and quality compared to the flattened, dose enhancements due to the bone scatter were found similar. However, we discovered that depth dose deviation due to the presence of bone was sensitive to the beam obliquity.
The porcine HapMap project: Genome-wide assessment of nucleotide diversity, haplotype diversity and footprints of selection in the pig (2010)

The Porcine HapMap Consortium The pig has a complex and long history of domestication and breed formation and has been domesticated independently multiple times and has likely experienced introgression of local Wild boar after the spread of agriculture. Using the Illumina GA sequencing platform thousand s of SNPs were identified in the porcine genome and used these to develop the Illumin porcine 60K iSelect Beadchip. This chip has enabled whole-genome characterization of linkage disequilibrium and haplotype structure in commercial and local breeds and comparison with the Wild boar. The chip has also allowed an investigation into whole-genome patterns of variation, including signatures of selection associated with domestication and breed formation as well as elucidating demographic events such as population bottlenecks, and providing insights into the complex origin of domesticated populations by examining patterns of haplotype sharing. Signatures of selection were also identified using Illumina short read sequences generated from pooled reduced representation libraries of different breeds and covering approximately 2% of the genome. Signals of positive selection were identified and a GO term/KEGG pathway enrichment analysis provided evidence for specific gene families under selection in domesticated pigs and Wild boar. Currently approximately 2,000 pigs were been genotyped with the porcine 60K beadchip, including approximatley 50 pig breeds, and about 20 different Wild boar populations distributed throughout Eurasia. In addition, museum and archeological samples were included to provide a wider insight into domestication and geographic history. Inclusion of a range of other Suidae as outgroup species, supported an estimation of ancestral alleles and the origin and relative age of the porcine SNPs.
High-power resonant measurements of piezoelectric materials: Importance of elastic nonlinearities (2001)

A resonance method for measuring the complex elastic and electromechanical properties of piezoelectric materials under high-power operational conditions has been developed. In this method, rectangular specimens are piezoelectrically driven into mechanical resonance. The displacement of the transverse resonance mode is measured as a function of frequency (f ) using an optical vibrometer method in conjunction with a frequency response analyzer. Due to the wide amplitude sensitivity range of the detection system, asymmetries in nonlinear resonance curves with mechanical damping can be accurately measured. The method has been applied to the study of Pb(Zr1−xTix)O3. Under resonant high-power drive, it has been found that electromechanical nonlinearities are due to elastic ones, as the elastic and electromechanical properties were both found to scale with the square of the strain amplitude. The temperature (T) and ac electric field (Eac) dependence of the mechanical quality factor Qm were also determined. Iso-Qm curves were constructed that can be used to predict performance criteria for high-power applications of piezoelectric materials.
Secretory immune response and clinical sequelae of Salmonella infection in a point source cohort. (1994)

To determine the kinetic isotypic serum and secretory immune response to Salmonella enteritidis in a cohort of individuals exposed to the organism in a single food source outbreak of dysentery. To determine the clinical outcome and immunogenetics of the exposed cohort and to correlate these features with the immune response.Following a single point source outbreak of Salmonella enteritidis, a cohort of dysenteric individuals were ascertained using a reactive arthritis screening questionnaire (QUEST). Serum and stimulated saliva samples were obtained at 6, 12, and 24 months following the outbreak of dysentery; examinations were conducted at the same time. Two unexposed control groups were ascertained: (1) general rheumatology clinic patients and (2) well nonarthritic family practice patients. An ELISA to determine quantitative IgA responses to Salmonella enteritidis lipopolysaccharide (LPS) was performed.Eleven of the 84 exposed individuals with dysentery developed reactive arthritis (ReA) of reactive enthesitis (ReE). There was a prolonged salivary IgA anti-LPS response in both the ReA/ReE and DYS (dysentery alone) patients compared with unexposed controls. A ratio of salivary IgA anti-LPS/serum IgA anti-LPS > 1 was associated with a good outcome (remission) of ReA, whereas a ratio < 1 was associated with chronic disease.There is a more prolonged humoral immune response to Salmonella LPS in exposed individuals than hitherto described. A risk factor in the prolongation of ReA is the inability to mount an appropriate specific salivary (secretory) immune response.
FAST POLARIZATION ANALYSIS BY NONLINEAR OPTICAL STOKES ELLIPSOMETERY (NOSE) (2007)

Author Institution: Department of Chemistry, Purdue University, Lafayette, Indiana 47907.
Primary Congenital Upper Eyelid Retraction in Infants and Children (2004)

Four infants with unilateral or bilateral eyelid retraction were examined. A full clinical evaluation revealed no ocular or systemic pathology. In all cases, clinical examination, thyroid function tests, and neuroimaging of the brain and orbits revealed no underlying disease process. The eyelid retraction did not change over the follow-up period of 2 to 6 years. Unilateral or bilateral eyelid retraction in infants and children may be an isolated clinical entity without an associated underlying disease.
Physicochemical properties of rice grain and starch from lines differing in amylose content and gelatinization temperature (1972)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPhysicochemical properties of rice grain and starch from lines differing in amylose content and gelatinization temperatureNgamchuen Kongseree and Bienvenido O. JulianoCite this: J. Agric. Food Chem. 1972, 20, 3, 714–718Publication Date (Print):May 1, 1972Publication History Published online1 May 2002Published inissue 1 May 1972https://pubs.acs.org/doi/10.1021/jf60181a020https://doi.org/10.1021/jf60181a020research-articleACS PublicationsRequest reuse permissionsArticle Views390Altmetric-Citations35LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Determination of relevant material behavior for use in stretchable electronics (2018)

Stretchable electronics getting more and more in focus for medical applications (e.g. skin wearable body-monitoring systems or sensitivs implants). Typically, electronic components and metal conductor paths are embedded in elastomeric substrates. These material combinations of highly elastic behavior of the substrate (strains up to ~ 150 %) and the relatively stiff metal components with a typical elastic stretchability (Cu <; 1 %) cause a problem regarding the mechanical reliability. The important factor for reliability assessment by FEM is not only the material properties of individual components, but also the behavior of metal-polymer interfaces. Accurate prediction of component behavior requires both, suitable material models and accurate material properties data. In this paper, we present our results of an adapted approach to assess material properties by mechanical test methods under plane stress conditions, under tensile loads and equi-biaxial tension experiments using an uniaxial testing machine. These results were used for the modelling of hyper-elastic material properties under multi-axial states of stress. This study is part of very important research to develop new simulation techniques and testing methods to be able to use hyper-elastic modelling approaches for industrial applications.
Study on biological activity of chitosan after radiation processing (2008)

In recent years there is a trend in industry to limit the usage of chemical compounds. Natural polymers are new promising materials that possess important properties like biodegrability or lack of toxicity. Radiation processing of natural occurring polymers is an area of current research for development of new applications. The aim of this study was to determine the impact of ionizing radiation modification on bioactivity of a natural polysaccharide. Chitosan with different molecular weights was investigated as a biostimulator - a biologically active substance that stimulates some growth processes in plants. Chitosan in solid state was irradiated with electron beam from an electron beam accelerator Elektronika 10-10 with a dose range from 50 to 300 kGy. The effects of irradiation on the molecular weight of chitosan were investigated by viscosity and GPC measurements. Non-irradiated and irradiated chitosan at concentrations 0.001, 0.01, 0.1 and 1 g/dm 3 were used for greenhouse tests of its activity for growth promotion of Salix viminalis L. var. gigantea plant. Uniform rooted cuttings (20 per combination) were selected for the test and cultivated in aerated hydroponics culture containing Hoagland's nutrient solutions plus respective amounts of chitosan. After six weeks of plant exposure to chitosan, data of selected parameters of plant growth were collected. In most cases, except the highest concentration, both forms of chitosan had stimulatory effect on leaf area, length of roots and of newly developed shoots. Also fresh and dry weights of these organs were greater in chitosan treated plants. The highest concentration of chitosan was stimula- tory only for a number of roots and newly developed shoots while for other parameters was inhibitory. In comparable concentrations the stimulatory effect was greater for chitosan irradiated in comparison with the non-irradiated one.
Polyharmonic Distortion modeling of RF BAW components (2015)

For the first time the Polyharmonic Distortion (PHD) model has been used to characterize the nonlinearities of Bulk Acoustic Wave (BAW) components. For that purpose a measurement setup has been developed by extending a nonlinear vector network analyzer with required external components enabling X-parameter measurements at high power levels. By discussion of selected components of the BAW resonator's PHD model and performing simulations in an RF design environment the importance of PHD model for improved BAW filter design has been demonstrated.
Stages of Embryonic Development of the Ice Goby (Shiro-uo), Leucopsarion petersii (1999)

A series of normal stages for the embryonic development of the ice goby (shiro-uo), Leucopsarion petersii, which belongs to the Perciformes, is described. Stages are based on morphological features, by utilizing the optical transparency of live embryos from the first cleavage to the hatching stage. Fertilized eggs were obtained by artificial insemination and normal embryogenesis was accomplished in a defined medium in plastic petri dishes at 19°C. Shiro-uo eggs were surrounded by a very thin and clear chorion and could be dechorionated with forceps very easily. Developmental stages were mostly comparable to those of other fish embryos described so far, but several differences were indicated, such as the third cleavage plane being horizontal, and that the length of the cleavage cycle increased gradually from the very early stages. Also, there were differences in the relative rates of organogenesis of the brain, eyes, otic vesicles, and somites when compared to the zebrafish and medaka.
Convection Enhanced Delivery of Optogenetic Adeno-associated Viral Vector to the Cortex of Rhesus Macaque Under Guidance of Online MRI Images (2019)

In non-human primate (NHP) optogenetics, infecting large cortical areas with viral vectors is often a difficult and time-consuming task. Here, we demonstrate the use of magnetic resonance (MR)-guided convection enhanced delivery (CED) of optogenetic viral vectors into primary somatosensory (S1) and motor (M1) cortices of macaques to obtain efficient, widespread cortical expression of light-sensitive ion channels. Adeno-associated viral (AAV) vectors encoding the red-shifted opsin C1V1 fused to yellow fluorescent protein (EYFP) were injected into the cortex of rhesus macaques under MR-guided CED. Three months post-infusion, epifluorescent imaging confirmed large regions of optogenetic expression (>130 mm<sup>2</sup>) in M1 and S1 in two macaques. Furthermore, we were able to record reliable light-evoked electrophysiology responses from the expressing areas using micro-electrocorticographic arrays. Later histological analysis and immunostaining against the reporter revealed widespread and dense optogenetic expression in M1 and S1 corresponding to the distribution indicated by epifluorescent imaging. This technique enables us to obtain expression across large areas of the cortex within a shorter period of time with minimal damage compared to the traditional techniques and can be an optimal approach for optogenetic viral delivery in large animals such as NHPs. This approach demonstrates great potential for network-level manipulation of neural circuits with cell-type specificity in animal models evolutionarily close to humans.
Ergosterol peroxide activates Foxo3-mediated cell death signaling by inhibiting AKT and c-Myc in human hepatocellular carcinoma cells (2016)

Sterols are the important active ingredients of fungal secondary metabolites to induce death of tumor cells. In our previous study, we found that ergosterol peroxide (5α, 8α-epidioxiergosta-6, 22-dien-3β-ol), purified from Ganoderma lucidum, induced human cancer cell death. Since the amount of purified ergosterol peroxide is not sufficient to perform in vivo experiments or apply clinically, we developed an approach to synthesize ergosterol peroxide chemically. After confirming the production of ergosterol peroxide, we examined the biological functions of the synthetic ergosterol peroxide. The results showed that ergosterol peroxide induced cell death and inhibited cell migration, cell cycle progression, and colony growth of human hepatocellular carcinoma cells. We further examined the mechanism associated with this effect and found that treatment with ergosterol peroxide increased the expression of Foxo3 mRNA and protein in HepG2 cells. The upstream signal proteins pAKT and c-Myc, which can inhibit Foxo3 functions, were clearly decreased in HepG2 cells treated with ergosterol peroxide. The levels of Puma and Bax, pro-apoptotic proteins, were effectively enhanced. Our results suggest that ergosterol peroxide stimulated Foxo3 activity by inhibiting pAKT and c-Myc and activating pro-apoptotic protein Puma and Bax to induce cancer cell death.
Effects of serotonin<sub>1</sub>-like receptor agonists on autonomic neurotransmission (1991)

Serotonin1A receptor agonists, 8-hydroxy-2-(di-n-propylamino)tetralin and 10-methyl-11-hydroxyaporphine, inhibited electrical stimulation-induced contraction of the guinea-pig ileum. These agonists also inhibited the pressor and tachycardiac responses to low frequency (0.25 Hz) but not to high frequency (2.0 Hz) electrical stimulation of the sympathetic nervous system in pithed rats. Serotonin1B receptor agonist RU 24969 inhibited pressor and tachycardiac responses to both low and high frequencies of stimulation in pithed rats. In the cat nictitating membrane, serotonin1A receptor agonists did not alter contractions elicited by electrical stimulation (0.1-3.0 Hz). Serotonin not only contracted the cat nictitating membrane but also facilitated contractile responses to low frequency (0.1-1.0 Hz) stimulation. The contractile effect of serotonin in the cat nictitating membrane was blunted by bretylium, methysergide, and ketanserin, but not by metoclopramide. The facilitatory effect of serotonin was antagonized by methysergide, but not by ketanserin, pindolol, propranolol, or metoclopramide. These results suggest that serotonin1A receptors modulate autonomic neurotransmission in the guinea-pig ileum and pithed rats, but not in the cat nictitating membrane. Serotonin contracts the cat nictitating mebrane via serotonin2 subtypes, while facilitating stimulated contractile responses through the serotonin1-like receptors.
Gelatin coacervate microcapsules containing sulphamerazine: Their preparation and the <i>in vitro</i> release of the drug (1968)

Abstract An improved method is described for the preparation of gelatin coacervate microcapsules containing sulphamerazine as a fine deflocculated powder. The factors which control both the coacervation step and the recovery of the microcapsules are discussed. The in vitro release of sulphamerazine from microcapsules of different wall thickness which had been hardened by formaldehyde under different conditions has been studied. The method of preparation gave a high percentage of encapsulated material in comparison with other recovery techniques.
Heavy Chain Variable Region Gene Utilization in Human Antibodies (1990)

We have sequenced by the polymerase chain reaction the heavy chain variable regions of over thirty human antibodies of defined specificity. The distribution of VH families in this group of antibodies is disproportionately skewed toward the recently discovered VH gene families. Within a family, there is also a disproportional use of individual gene segments. Numerous explanations for these imbalances are discussed.
Antioxidant Capacity and Lipid Characterization of Six Georgia-Grown Pomegranate Cultivars (2009)

Six pomegranate (Punica granatum) cultivars were investigated for their antioxidant capacity and lipid profile. Total polyphenols were determined according to the Folin-Ciocalteau method. Major organic acids and phenolic compounds were analyzed by RP-HPLC. Two in vitro antioxidant assays, ferric reducing antioxidant power and Trolox equivalent antioxidant capacity, were used to assess antioxidant capacity. Total lipid was extracted according to the Folch method, and fatty acid methyl esters were determined by GC. Tocopherols and phospholipids were identified and quantified by NP-HPLC using a fluorescence detector for tocopherols and an evaporative light scattering detector for phospholipid analysis. Phytosterols were analyzed by GC. The predominant organic acid was citric acid followed by malic acid. The peel fraction had the highest total hydrolyzable tannins content (4792.3-6894.8 mg/100 g of FW). Overall, the highest antioxidant capacity was found in leaves followed by peel, pulp, and seed. Pomegranate seed had an average lipid content of 19.2% with punicic acid as the predominant fatty acid. Pomegranate seed had high contents of alpha-tocopherol (161.2-170.1 mg/100 g) and gamma-tocopherol (80.2-92.8 mg/100 g).