gebhart/patrepeval huggingface dataset:
The lateral superjunction PSOI LIGBT and LDMOSFET (2012)

This paper presents a comparison between the superjunction LIGBT and the LDMOSFET in partial silicon-on-insulator (PSOI) technology in 0.18μm PSOI HV process. The superjunction drift region helps in achieving uniform electric field distribution in both structures but also contributes to the on-state current in the LIGBT. The superjunction LIGBT successfully achieves breakdown voltage (BV) of 210V with R <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">dson</inf> of 765mΩ.mm2. It exhibits reduced specific on-state resistance R <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">dson</inf> and higher saturation current (I <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">dsat</inf> ) for the same BV compared to a compatible lateral superjunction LDMOS in the same technology.
Operator interactions by the <i>Bacillus subtilis</i> arginine repressor/activator, AhrC: novel positioning and DNA‐mediated assembly of a transcriptional activator at catabolic sites (1997)

We have previously reported the initial characterization of a catabolic operator site (O[rocA]) for the Bacillus subtilis arginine repressor/activator protein AhrC. Here, we present the characterization by gel retardation and DNase I footprinting of both O(rocA) and a second catabolic operator site, O(rocD). Both operator sites encompass a single recognition site, an ARG box, located immediately upstream of the transcriptional start points, a unique positioning for a transcriptional activator protein. Although there is considerable sequence homology between the two catabolic operator sites, they vary significantly, around twofold, in their apparent affinities for the protein (K'd approximately 90 nM for O[rocA] and approximtaely 190nM for O[rocD]). This difference may result from the lower match to the ARG box consensus of the O(rocD) site. Both catabolic operators show evidence for co-operative binding with respect to protein concentration. Determination of the sequences of two AhrC catabolic operator sites, in combination with the three such biosynthetic sites, has allowed the derivation of an improved B. subtilis ARG box consensus sequence, CATGAATAAAAATg/tCAAg/t. This is not identical to the Escherichia coli consensus operator for the AhrC homologue, ArgR, which may explain the only partial cross-functioning of these proteins in vivo. The O(rocA) site is adjacent to a sharp, stable bend located 5' to the catabolic operator. Circular permutation analysis has been used to determine the relative angle of bend (approximately 50 degrees), its location and the effect of adding magnesium ions and/or AhrC protein. Protein binding increases the relative bend angle to approximately 85 degrees. Bending is shown to be associated with a number of A-tracts in the upstream sequence. However, altering the phasing of the A-tracts has little effect on the affinity for AhrC. Truncation and competition experiments have been used to investigate the possible role of sequences flanking the operator on affinity. Very surprisingly, the affinity of the O(rocA) site appears to increase in the presence of excess, specific competitor fragment, i.e. the system shows anti-competitive effects. Competition is restored at high molar excesses of specific fragment over the protein. We propose a novel model for the assembly of a higher affinity form of AhrC at operator sites that is consistent with both the apparent co-operativity of binding and the anti-competitive effects. These data suggest that the molecular interactions occurring between the prokaryotic arginine-regulatory proteins and their operators may be more complex than is generally appreciated.
ONR-NRL superconducting materials symposium. A forecast. Memorandum report (1979)

Partial contents include: Ternary Compounds; Granular Superconductors; Superconductivity in (Sn)x and its Halogen Derivative (SnBr0.4)x; Studies of CuCl at Elevated Pressures; Superconducting Properties of Hydride Systems; Thin Film Superconducting Materials Research; Synthesis of Superconducting Nb3Si using High Pressures; Synthesis of Unstable A-15 Compounds by Epitaxial Recrystallization of Ion Implanted Layers; and Sputtering of Nb3Si.
TRAUMATIC RUPTURE OF THE THORACIC AORTA (1954)

TRAUMATIC rupture of the thoracic aorta is rare, but even more unusual are reports of long survival with this lesion. Because of the long survival in this particular case and the possibility that some of these unfortunate patients may be saved, this paper is presented. One reason for the lack of knowledge concerning this lesion lies in the fact that most cases are diagnosed only at necropsy. The rapid state of shock and coma inwhich the patient remains until death, plus the concomitant severe injuries in other parts of the body, make the diagnosis during life very difficult. Strassmann<sup>1</sup>reports on 72 cases of traumatic aortic rupture from approximately 7,000 autopsies done from 1936 to 1942 at the Chief Medical Examiner's Office in New York City. In this series, 42 patients were less than 50 years old and except for the results of trauma showed no visible gross pathologic change
Cross reactive cellular immune responses in chickens previously exposed to low pathogenic avian influenza (2011)

Taken together these data extend the findings that cellular immunity, including CTL's, is cross reactive against heterologous isolates of AI and contribute to protection following infection.
Turbulence Model Behavior in Low Reynolds Number Regions of Aerodynamic Flowfields (2009)

The behaviors of the widely used Spalart-Allmaras and Menter shear-stress transport turbulence models at low Reynolds numbers and under conditions conducive to relaminarization are documented. The flows used in the investigation include 2-D zero-pressure-gradient flow over a flat plate from subsonic to hypersonic Mach numbers, 2-D airfoil flow from subsonic to supersonic Mach numbers, 2-D subsonic sink flow, and 3-D subsonic flow over an infinite swept wing (particularly its leading-edge region). Both models exhibit a range over which they behave transitionally even with inflow values set to cause immediate growth of the turbulence quantities, in the sense that the flow is neither laminar nor fully turbulent, but these behaviors are different: the shear-stress transport model typically has a well-defined transition location, whereas the Spalart-Allmaras model does not. Both models are predisposed to delayed activation of turbulence with increasing freestream Mach number. Also, both models can be made to achieve earlier activation of turbulence by increasing their freestream levels, but too high a level can disturb the turbulent solution behavior. The technique of maintaining freestream levels of turbulence without decay in the shear-stress transport model, introduced elsewhere, is shown here to be useful in reducing grid dependence of the model's transitional behavior. Both models are demonstrated to be incapable of predicting relaminarization; eddy viscosities remain weakly turbulent in accelerating or laterally strained boundary layers for which experiment and direct simulations indicate turbulence suppression. The main conclusion is that these models are intended for fully turbulent high Reynolds number computations, and using them for transitional (e.g., low Reynolds number) or relaminarizing flows is not appropriate. Competing models which fare better in these areas have not been identified.
Association between incident cancer and subsequent stroke (2014)

Incident cancer is associated with an increased short-term risk of stroke. This risk appears highest with lung, pancreatic, and colorectal cancers.
Evaluation and Management of Proteinuria and Nephrotic Syndrome in Children: Recommendations From a Pediatric Nephrology Panel Established at the National Kidney Foundation Conference on Proteinuria, Albuminuria, Risk, Assessment, Detection, and Elimination (PARADE) (2000)

These recommendations are intended to provide primary care physicians with a useful reference when they are faced with a young child or teenager who presents with proteinuria, whether this is mild and asymptomatic or more severe, leading to nephrotic syndrome.
A Patient with Lung Squamous Cell Carcinoma Presenting with Severe Cardiac Dysfunction Similar to Dilated Cardiomyopathy with Left Bundle Branch Block Induced by Myocardial Metastasis (2014)

A patient with severe cardiac dysfunction similar to dilated cardiomyopathy expired because of lung squamous cell carcinoma. He was admitted with respiratory failure and was diagnosed with congestive heart failure due to dilated cardiomyopathy based on the chest X-ray, electrocardiography, echocardiography, and coronary angiography. Chest computed tomography showed a mass shadow in the right lower lobe, and the patient was diagnosed with lung squamous cell carcinoma by bronchoscopy. The patient expired, and the autopsy revealed that a myocardial metastasis disrupted the cardiac-conduction system without dilated cardiomyopathy in myocytes. Left bundle branch block caused by myocardial metastasis presumably induced left cardiac dysfunction.
Growth kinetics and orientation dependence of dislocation loop, in electron irradiated aluminum (1973)

Abstract Quantitative studies show that the defect cluster production and growth rates, as a result of 200 kV electron irradiation of aluminum, are strongly influenced amongst several factors by crystal thickness, crystal orientation, impurity content and room temperature vacancy mobility. Strong evidence of vacancy mobility is obtained from the very low point defect retention ratio observed experimentally. Considerable insight into the defect production and retention process can be obtained by an analysis of the dislocation loop growth rate data according to models based on chemical reaction rate theory. As a result, the migration energy for free interstitials in aluminum is estimated to be 0.06 eV, while with strong interstitial-impurity binding the migration energy is 0.4 eV. Analysis of the electron irradiation data in aluminum suggests that interstitial-impurity binding controls defect cluster nucleation. Further evidence for this is obtained by comparing the surface denuded zone width calculated by assuming interstitial-impurity binding with that observed experimentally. Dislocation loop growth rates analyzed according to the kinetic models show that the surfaces influence the initial loop growth while bulk behavior is approached at a later state. There is considerable orientation dependence of damage observed between the <100> and <111> orientations. Maximum damage rates are observed at exact low index orientations with sharp drop offs by a factor of ∼ 3 when the crystal is tilted 3-5° away from these orientations.
Novel splicing mutation in the progranulin gene causing familial corticobasal syndrome (2006)

Corticobasal syndrome (CBS) is a rare cognitive and movement disorder characterized by asymmetric rigidity, apraxia, alien-limb phenomenon, cortical sensory loss, myoclonus, focal dystonia, and dementia. It occurs along the clinical spectrum of frontotemporal lobar degeneration (FTLD), which has recently been shown to segregate with truncating mutations in progranulin (PGRN), a multifunctional growth factor thought to promote neuronal survival. This study identifies a novel splice donor site mutation in the PGRN gene (IVS7+1G-->A) that segregates with CBS in a Canadian family of Chinese origin. We confirmed the absence of the mutant PGRN allele in the RT-PCR product which supports the model of haploinsufficiency for PGRN-linked disease. This report of mutation in the PGRN gene in CBS extends the evidence for genetic and phenotypic heterogeneity in FTLD spectrum disorders.
Total Synthesis of Longifolene (1964)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTTotal Synthesis of LongifoleneE. J. Corey, Masaji. Ohno, Rajat B. Mitra, and Paul A. VatakencherryCite this: J. Am. Chem. Soc. 1964, 86, 3, 478–485Publication Date (Print):February 1, 1964Publication History Published online1 May 2002Published inissue 1 February 1964https://pubs.acs.org/doi/10.1021/ja01057a039https://doi.org/10.1021/ja01057a039research-articleACS PublicationsRequest reuse permissionsArticle Views7053Altmetric-Citations146LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Experimental Infection of Humans with Filariae (1991)

This report summarizes the findings of the 17 published studies involving humans who have been experimentally infected with filarial parasites. Over the past 60 years, 45 individuals have been deliberately infected with Wuchereria bancrofti, Brugia malayi, Brugia pahangi, Loa loa, Mansonella perstans, Mansonella ozzardi, and/or Onchocerca volvulus. The findings from these experimental infections of humans have helped define microfilarial survival and periodicity within human hosts, the prepatent period for the causative agents of lymphatic filariasis, etiologic agents for particular clinical syndromes, immunologic and hematologic consequences of filarial infection, and the role of chemotherapeutic agents in the prevention and treatment of filarial infections.
Quasi-monolithic structures for spaceflight using hydroxide-catalysis bonding (2012)

Next generation space telescopes and interferometric missions will require stringent position and stability tolerances. To do this, these missions will require materials and bonding techniques with ever-increasing stability in order to make their measurements. As an example, the Laser Interferometer Space Antenna (LISA) will detect and observe gravitational waves in the 0.1 mHz to 1 Hz frequency range with strain sensitivities on the order of 10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">-21</sup> at its most sensitive frequency. To make these measurements, critical components such as the optical bench or telescope support structure will need to have path-length stabilities of better than 1 pm/√Hz. The baseline construction method for the LISA optical bench is to affix fused silica components to a Zerodur baseplate using hydroxide-catalysis bonding (HCB). HCB is a recently developed technique that allows the bonding of glasses, some metals, and silicon carbide with significant strength and stability with a bond thickness of less than a few micrometers. In addition, a wide range of surface profiles can be bonded using only a small amount of hydroxide solution. These characteristics make HCB ideal for adhering components in complex optical systems. In addition to being used to construct the LISA optical bench, the HCB technique shows great promise for constructing other structures such as hollow retroreflectors to be used for lunar laser ranging, or a visible nulling coronograph to be used for exoplanet detection. Here we present construction techniques that could be used to make an optical bench, hollow retroreflector, nulling coronograph, or other quasi-monolithic structures using HCB. In addition, we present dimensional stability results of an optical bench that was made using HCB, as well as HCB strength measurements.
Space Shuttle Flight Crew Spatial Orientation Survey Results (2012)

Based upon our results, long-duration missions may induce orientation problems that could have significant mission impacts.
Identification of molecules derived from human fibroblast feeder cells that support the proliferation of human embryonic stem cells (2010)

The majority of human embryonic stem cell lines depend on a feeder cell layer for continuous growth in vitro, so that they can remain in an undifferentiated state. Limited knowledge is available concerning the molecular mechanisms that underlie the capacity of feeder cells to support both the proliferation and pluripotency of these cells. Importantly, feeder cells generally lose their capacity to support human embryonic stem cell proliferation in vitro following long-term culture. In this study, we performed large-scale gene expression profiles of human foreskin fibroblasts during early, intermediate and late passages using a custom DNA microarray platform (NeuroStem 2.0 Chip). The microarray data was validated using RT-PCR and virtual SAGE analysis. Our comparative gene expression study identified a limited number of molecular targets potentially involved in the ability of human neonatal foreskin fibroblasts to serve as feeder cells for human embryonic stem cell cultures. Among these, the C-KIT, leptin and pigment epithelium-derived factor (PEDF) genes were the most interesting candidates.
Design and implementation of a privacy preserving electronic health record linkage tool in Chicago (2015)

Software that standardizes the assignment of a unique seeded hash identifier merged through an agreed upon third-party honest broker can enable large-scale secure linkage of EHR data for epidemiologic and public health research. The software algorithm can improve future epidemiologic research by providing more comprehensive data given that patients may make use of multiple healthcare systems.
A numerical investigation into key factors controlling hard rock excavation via electropulse stimulation (2020)

Electropulse stimulation provides an energy-efficient means of excavating hard rocks through repeated application of high voltage pulses to the rock surface. As such, it has the potential to confer significant advantages to mining and drilling operations for mineral and energy resources. Nevertheless, before these benefits can be realized, a better understanding of these processes is required to improve their deployment in the field. In this paper, we employ a recently developed model of the grain-scale processes involved in electropulse stimulation to examine excavation of hard rock under realistic operating conditions. To that end, we investigate the maximum applied voltage within ranges of 120–600 kV, to observe the onset of rock fragmentation. We further study the effect of grain size on rock breakage, by comparing fine (granodiorite) and coarse grained (granite) rocks. Lastly, the pore fluid salinity is investigated, since the electric conductivity of the pore fluid is shown to be a governing factor for the electrical conductivity of the modeled system. This study demonstrates that all investigated factors are crucial to the efficiency of rock fragmentation by electropulsing.
Transurethral coil embolization for the management of ureteroarterial fistula: a case report. (2004)

A 71-year-old woman who had undergone a total abdominal hysterectomy and pelvic irradiation for cervical cancer and fecal diversion for adhesive ileus was referred to us for a "left" ureteral stone and intermittent gross hematuria. Bilateral ureteral stents had been indwelled because of lower ureteral strictures for a long time. Hematuria continued after the removal of the ureteral stone, and she once went into hypovolemic shock at the time of exchange of the right ureteral catheter. Selective arteriography revealed a "right" ueteroarterial fistula. Endovascular management alone failed to resolve the fistula, but a subsequent transurethral metal coil embolization was effective, and the hematuria was relieved. She is still free from disease at 7-month followup. As far as we know, there has been no previous report of a transurethrally managed ureteroarterial fistula.
Ultrafast electronic spectroscopy for chemical analysis near liquid water interfaces: concepts and applications (2009)

Electron spectroscopy for chemical analysis (ESCA) being conceptually a photoelectron spectroscopy is established as a chemically specific probe mostly for surface analysis. Liquid phase ESCA for volatile liquids has become possible through the development of the liquid microjet technique in vacuum enabling the measurement of liquid interface photoelectron emission at the high vapor pressure of volatile liquids. Recently we have been able to add the dimension of time to the liquid interface ESCA technique employing high-harmonics soft X-ray and UV/near IR femtosecond pulses in combination with liquid water micro beams in vacuum. The concepts as well as technical details are outlined and several characteristic applications are highlighted.
Selective photolysis of the azido groups in 2,4-diazidopyridines (2000)

Selective photolysis of the α-azido group in 2,4-diazidopyridines has been determined by EPR spectroscopy and theoretically treated in terms of non-adiabatic photodissociation processes.
Modeling anthropomorphism in dynamic human arm movements (2010)

Human motor control has always acted as an inspiration in both robotic manipulator design and control. In this paper, a modeling approach of anthropomorphism in human arm movements during every-day life tasks is proposed. The approach is not limited to describing static postures of the human arm but is able to model posture transitions, in other words, dynamic arm movements. The method is based on a novel structure of a Dynamic Bayesian Network (DBN) that is constructed using motion capture data. The structure and parameters of the model are learnt from the motion capture data used for training. Once trained, the proposed model can generate new anthropomorphic arm motions. These motions are then used for controlling an anthropomorphic robot arm, while a measure of anthropomorphism is defined and utilized for assessing resulted motion profiles.
Biochemical Studies on Microorganisms. XVII (1949)

The authors previously isolated 12 kinds of soil bacteria which could metabolize benzoic acid or its derivatives and examined their metabolic activities. In the present experiment, the authors isolated further kinds of soil bacteria possessing metabolic activities different from the former 12. Comparative studies on the metabolism of these bacteria were made with benzoic, p-hydroxybenzoic, salicylic, m-hydroxybenzoic, anisic, piperonylic. p-nitrobenzoic, phenylacetic, cinnamic, o-coumaric and dl-mandelic acids. Some bacteria metabolized p-methoxycinnamic acid.
Production de radicaux libres par réaction entre le diéthyl-zinc et des composés peroxydes (1975)

La réaction entre le diéthyl-zinc et les peroxydes est étudiée du point de vue chimique : elle est violente avec l’hydro- peroxyde de cumyle ou les peroxydes de diacyle, mais modérée avec le peroxyde de dicumyle. Outre l’hydrolyse observée dans le cas de l’hydroperoxyde, la réaction conduit à la formation d'éthane, de composés alcoxy, et de butane en quantité variable selon la nature du peroxyde. La technique de piégeage de radicaux par un composé nitroso met en évidence la présence de radicaux éthyles quelles que soient les conditions expérimentales; on peut observer aussi des radicaux alcoxyles ou acyloxyles en présence d’excès de peroxyde. Des schémas réactionnels sont proposés pour rendre compte de ces résultats.