gebhart/patrepeval huggingface dataset:
Pentoxifylline Alleviates Cardiac Ischemia and Dysfunction Following Experimental Angina in Insulin Resistance (2014)

We have previously shown that pentoxifylline (PTX) protects from vascular complications associated with insulin resistance (IR). Here, we investigated the protective effect of PTX against cardiac ischemia and dysfunction following experimental angina in IR. IR, along with its accompanying cardiac dysfunction, was induced in rats by a high-fructose (10% in drinking water) high-fat diet for 12 weeks. PTX was administered daily (30 mg⋅kg(-1)) during the last 4 weeks of the study. Experimental angina was induced by isoproterenol (10 µg⋅kg(-1)) administered by intravenous injection. Both before (baseline) and after the experimental angina, cardiac contractility was assessed by continuous recording in anesthetized rats via a microtip catheter inserted in the left ventricle, and cardiac conductivity was determined by a surface electrocardiograph. Serum glucose, insulin, tumor necrosis factor-α (TNFα), and adiponectin levels and lipid profile were also determined. Feeding the rats a high-fructose high-fat diet produced IR, as evidenced by significant hyperinsulinemia and hyperglycemia, and PTX administration did not affect this IR. When subjected to experimental angina, IR hearts were less resistant to the ischemia following induction of angina (reflected by the large ST height depression) compared with controls, and PTX completely prevented the excessive ST height depression in IR animals. In addition, left ventricular pressure development was largely attenuated during and after induction of angina in IR animals compared with controls. PTX administration prevented the excessive attenuation in ventricular pressure development in IR animals. IR was associated with elevated levels of the inflammatory cytokine TNFα, whereas PTX treatment elevated the serum level of the anti-inflammatory cytokine adiponectin. PTX alleviates cardiac ischemia and dysfunction following experimental angina in IR directly through inhibition of the low-grade inflammation that accompanies IR.
Song of the Compassionate Echoes in UN ＂Reflecting Confucius Analects Choral＂ in UNESCO HQ (2013)

Song of Compassionate--Reflecting Confucius Analects Choral(hereinafter referred to as the Choral) was jointly hosted by China’s Permanent Mission to UNESCO and China Literature and Arts Foundation,supported by China Classic Culture Communication and Exchange Committee,assisted by China Cultural Center in Paris,
Temperature Dependence of Fluorescence and Photoisomerization in Symmetric Carbocyanines.Influence of Medium Viscosity and Molecular Structure (1994)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTTemperature Dependence of Fluorescence and Photoisomerization in Symmetric Carbocyanines.Influence of Medium Viscosity and Molecular StructurePedro F. Aramendia, R. Martin Negri, and Enrique San RomanCite this: J. Phys. Chem. 1994, 98, 12, 3165–3173Publication Date (Print):March 1, 1994Publication History Published online1 May 2002Published inissue 1 March 1994https://pubs.acs.org/doi/10.1021/j100063a020https://doi.org/10.1021/j100063a020research-articleACS PublicationsRequest reuse permissionsArticle Views1385Altmetric-Citations165LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Real time sensor fusion for autonomous underwater imaging in 3D (2002)

In this paper a method that enables real-time visual and acoustical processing for 3D imaging is presented. This can be used for 3D-mapping of objects and environments, inspection and/or tracking or a "lock and hold" function for an autonomous underwater vehicle (AUV). The described method gives a framework for real-time 3D information processing and modelling. It makes monitoring of 3D features easy and speeds up higher level algorithms. In underwater vision there is no single sensor that can give solutions to all perceptual problems that may arise. There is a need for data from several sensors to f.x. obtain the desired accuracy and range. The sonar has good range properties but may often have poor angular resolution. On the other hand the camera has poor depth-measurements capabilities and a rather limited sensor-range, but it has good resolution and is able to detect non-structural properties of the observed object such at colour, paint etc. An important property of this method is the fact that the raw-data from the sensors are processed on the fly. The relevant information extracted from the raw-data are organised in a 3D structure. This gives a better signal to noise ratio input to subsequent algorithms. The idea has been investigated with success for the 3D sonar case. In this method there is a close integration between the sensors which is applied before the modelling, matching or identification of objects, making real-time 3D processing feasible at a low hardware cost.
Temperature Insensitive All-Fiber Compact Polarization-Maintaining Photonic Crystal Fiber Based Interferometer and Its Applications in Fiber Sensors (2010)

A novel temperature insensitive all-fiber compact polarization-maintaining photonic crystal fiber (PMPCF) based interferometer was presented. The coupling between the PMPCF and single mode fiber (SMF) was investigated experimentally and analytically. With an all-fiber compact SMF-PMPCF-SMF structure, the cladding modes propagating in the PMPCF can be effectively excited by finely core-offsetting one splice between the PMPCF and SMF. With the increase of the core-offset, the interference depth of the interference pattern enlarges accordingly. Under a suitable core-offset, the PMPCF based interferometer with high interference depth can be obtained. Moreover, it is temperature insensitive due to its ultra-low thermal characteristics. We also demonstrated its applications in strain and refractive index measurement. The sensors have the advantages of small size, simple and compact all fiber structure, high sensitivity, and temperature insensitiveness.
Ultrasensitive and Selective Colorimetric DNA Detection by Nicking Endonuclease Assisted Nanoparticle Amplification (2009)

One–two punch: Single stranded DNA sequences can be detected by nicking endonuclease assisted nanoparticle amplification (see picture). The detection system offers a colorimetric detection limit of 0.5 fmol within hours for selected oligonucleotides. Detection of DNA sequences with a single base mismatch or different lengths is also demonstrated. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
The benefit of mass eradication of <i>Helicobacter pylori</i> infection: a community-based study of gastric cancer prevention (2012)

Population-based eradication of H pylori infection has led to a significant reduction in gastric atrophy at the expense of increased oesophagitis. The ultimate benefit in reducing gastric cancer incidence and its mortality should be validated by a further long-term follow-up.
Design and Analysis of a Process for Melt Casting Metallic Fuel Pins Incorporating Volatile Actinides (2004)

After considering the heating mechanisms, casting issues, crucible design and issues related to the mass transport of americium, an ISM system was selected for melting the feedstock and casting fuel pins containing high vapor pressure actinides (americium). The finite element commercial software (FIDAP) was used to simulate the induction melting process and the casting process. Phase change is considered both in the heating and in the solidification process. Various factors and properties are studied, such as boundary conditions and initial conditions, output current, frequency of the current, main dimensions of the system, mold preheating temperature, heat transfer coefficient and mold material. As shown in simulated results, several conclusions can be drawn:\n• The design of the system has great impact on the induction melting process. In order to obtain high heat efficiency, the coils group number can be designed as many as possible and the coils are located as near to the crucible as possible.\n• The induction melting process is sensitive to the electrical factors and properties (Current density; frequency and output power). Through the control of these values we can control the melting process. The thermal properties of the feedstock and the crucible material are also important in the heating process.\n• A direct IH has a much higher efficiency than an indirect IH. In order to form the “skull”, a low temperature and good thermal conductivity of the coolant is necessary.\n• A VOF-Solidification process can be “divided” to a filling process and a solidification process and be studied respectively, especially for a case of low convective heat transfer coefficient value.\n• A constant filling pressure is expected rather than a constant velocity in the casting process.\n• Mold material, mold preheated temperature, inlet pressure, and heat transfer coefficient have relative large effects to the casting process.
Identification of a set of genes involved in the biosynthesis of the aminonucleoside moiety of antibiotic A201A from <i>Streptomyces capreolus</i> (2002)

A novel cosmid (pABC6.5) whose DNA insert from Streptomyces capreolus, the A201A antibiotic producer, overlaps the inserts of the previously reported pCAR11 and pCAR13 cosmids, has been isolated. These two latter cosmids were known to contain the aminonucleoside antibiotic A201A resistance determinants ard2 and ard1, respectively. Together, these three cosmids have permitted the identification of a DNA stretch of 19 kb between ard1 and ard2, which should comprise a large region of a putative A201A biosynthetic (ata) gene cluster. The sequence of the 7 kb upstream of ard1 towards ard2 reveals seven consecutive open reading frames: ataP3, ataP5, ataP4, ataP10, ataP7, ata12 and ataPKS1. Except for the last two, their deduced products present high similarities to an identical number of counterparts from the pur cluster of Streptomyces alboniger that were either known or proposed to be implicated in the biosynthesis of the N6,N6-dimethyl-3'-amino-3'-deoxyadenosine moiety of puromycin. Because A201A contains this chemical moiety, these ataP genes are most likely implicated in its biosynthesis. Accordingly, the ataP4, ataP5 and ataP10 genes complemented specific puromycin nonproducing Deltapur4, Deltapur5 and Deltapur10 mutants of S. alboniger, respectively. Amino acid sequence comparisons suggest that ata12 and ataPKS1 could be implicated in the biosynthesis of the d-rhamnose and alpha-p-coumaric acid moieties of A201A. Further sequencing of 2 kb of DNA downstream of ard1 has disclosed a region which might contain one end of the ata cluster.
A Comprehensive Orientation Program for Incoming Sixth Graders (1989)

might their children with a student in our sixth grade at the intermediate school. Experience has shown that one of the most successful techniques is to actually have the fifth graders spend a day with us, following sixth grade schedules. They are brought to the building, assigned a partner who travels with them all day so that they get the true sense of being an intermediate school student.
Increased epithelial cell proliferation in the colon of patients with acromegaly. (1996)

To gain insight into the possible physiological mechanisms responsible for the increased incidence of colonic neoplasms in patients with acromegaly, a prospective cohort study was carried out in 30 patients with acromegaly, a prospective cohort study was carried out in 30 patients with acromegaly. Seven patients had newly diagnosed acromegaly and 23 were studied during follow-up. Serum growth hormone and insulin-like growth factor-1 (IGF-1) were determined on two separate occasions. During diagnostic endoscopy, mucosal biopsies were obtained for immunohistochemical determination of sigmoidal epithelial cell proliferation, expressed as labeling index (LI). Duodenal and fecal bile acid analyses were performed using gas-liquid chromatography. Results were compared with normal ranges of the laboratory. An increased overall LI was found in 54% of the patients. Increased LI of the luminal, middle, and basal crypt compartments was found in 11, 64, and 28%, respectively. Similarly, comparisons of the mean +/- SEM of the overall LI and the LI of the middle and basal compartments between acromegalic patients and a control group showed overall LI 10.0 +/- 0.8% versus 5.7 +/- 0.6% (P < 0.001), middle LI 12.1 +/- 1.2% versus 5.0 +/- 0.6% (P < 0.001), and basal LI 17.1 +/- 1.3% versus 10.8 +/- 1.3% (P < 0.01). Duodenal and fecal bile acid proportions were within the normal ranges of the laboratory. There was a positive correlation between growth hormone and overall LI (r = 0.55, P < 0.01) by least square regression analysis. There was no correlation between duodenal bile acid composition and hormone levels. The proportion of secondary bile acids in feces correlated with growth hormone (r = 0.55, P < 0.05) as well as with IGF-1 (r = 0.59, P < 0.05). With multiple regression analyses, only a relation between overall LI and IGF-1 (P = 0.007) remained to hold true. Increased epithelial cell proliferation, most probably due to a direct stimulatory effect of especially IGF-1, contributes to the increased risk of colonic neoplasms in acromegaly.
Near‐Infrared Absorbing Polymeric Nanoparticles as a Versatile Drug Carrier for Cancer Combination Therapy (2013)

Abstract Poly(3,4‐ethylenedioxythiophene):poly(4‐styrenesulfonate) (PEDOT:PSS) nanoparticles, after being coated with polyethylene glycol (PEG), are used as a drug carrier to load various types of aromatic therapeutic molecules, including chemotherapy drugs doxorubicin (DOX) and SN38, as well as a photodynamic agent chlorin e6 (Ce6), through π – π stacking and hydrophobic interaction. Interesting functionalities of PEDOT:PSS‐PEG as an unique versatile drug delivery platform are discovered. Firstly, for water‐insoluble drugs such as SN38, the loading on PEDOT:PSS‐PEG dramatically enhances its water solubility, while maintaining its cytotoxicity to cancer cells. Secondly, the delivery of Ce6 by PEDOT:PSS‐PEG is able to remarkably accelerate the cellular uptake of Ce6 molecules, and thus offers improved photodynamic therapeutic efficacy. Using DOX‐loaded PEDOT:PSS‐PEG as the model system, it is demonstrated that the photothermal effect of PEDOT:PSS‐PEG can be utilized to promote the delivery of this chemotherapeutic agent, achieving a combined photothermal‐ and chemotherapy with an obvious synergistic cancer killing effect. Moreover, it is also shown that multiple types of therapeutic agents could be simultaneously loaded on PEDOT:PSS‐PEG nanoparticles and delivered into cancer cells. This work highlights the great potential of NIR‐absorbing polymeric nanoparticles as multifunctional drug carriers for potential cancer combination therapy with high efficacy.
Copper Electrowinning using Segmented Intercell Bars for Improved Current Distribution (2002)

The most widely used technology for obtaining pure copper (>99.999% Cu) from copper oxide ores is LIX-SX-EW (Leaching – Solvent Extraction – Electrowinning). In the EW step, the maximum current that can be applied is partially limited by the possibility of the formation of short circuits. The Walker configuration, despite its apparent robustness and simplicity, exhibits high dispersion of the electrode currents. This paper reviews the current distribution phenomena and proposes a Whitehead based configuration implemented with a multicircuit intercell bar to force the current balance. This arrangement drives the current through more balanced resistance circuits despite intrinsic process parameter deviations. A more even current distribution produces cathodes capable of complying with tighter standards improving chemical and physical cathode quality parameters. Also, the proposed configuration can decrease the probability of short circuit formation allowing operation at higher current densities. Finally, use of the proposed electrical arrangement makes possible the continuous measurement of the flow of current in each electrode using current sensors. This allows for the early detection/correction of short circuits and continuous monitoring of the current distribution in the whole cellhouse.
Rear Side Passivated and Locally Contacted Solar Cells with Laser Diffused Selective Emitter (2012)

For an improved solar cell performance rear side passivation and local contacts in combination with a laser diffused selective emitter were developed and cell efficiencies up to 19.5% were reached. Several fundamental physical impacts of major importance, such as the light trapping behaviour because of specific surface preparations, the resulting passivation performance, the interaction of emitter and rear surface recombination currents, were investi-gated. In the first test runs in a production environment average solar cell efficiencies of 18.6% and best cell efficiencies of 19.0% were successfully achieved under non-adapted production conditions.
Dysregulation of redox‐state‐regulating enzymes in melanocytic skin tumours and the surrounding microenvironment (2015)

Redox-regulating enzymes have the potential to serve as novel prognostic factors and targeting them may offer new therapeutic options in malignant melanoma.
Psychosocial Impact of C282Y Mutation Testing for Hemochromatosis (2001)

The aim of this study was to investigate the psychological effects of genetic testing for hemochromatosis. Study participants included cases discovered through a population screening study in 5211 voluntary blood donors (n = 25) and patients referred for diagnostic evaluation for hemochromatosis (n = 117). Participants completed questionnaires (Spielberger State-Trait Anxiety Index, Medical Outcomes Survey Short Form 36) before and after genetic testing. A subset of participants from the screening study was also interviewed 1 year after testing (Feelings About Test Results Measure). Additional questions included data on insurance applications, time off from work, and family issues. Anxiety significantly decreased in homozygotes and heterozygotes after genetic testing and remained constant in C282Y mutation-negative cases. Vitality and physical composite scores improved after genetic testing. There were no significant deleterious psychological effects of genetic testing on anxiety and on mental and physical health status. There were no negative effects discovered on insurance or time off work. This study has not demonstrated deleterious effects of genetic testing for hemochromatosis on anxiety, mental health and physical health status, insurance, or time off from work. Genetic testing for hemochromatosis is well accepted and should not be discouraged on the basis of potential adverse psychosocial effects.
Kim Moodie : Recent Work (1999)

Catalogue to accompany an exhibition of Moodie’s recent paintings, prints and drawings (1996-1999). Curator J. Patten exposes “the ambivalent nature and rhizomatous structure” of the artist’s production, discussing the themes of knowledge and written language, colonialism, conquest domination, carnival, human folly, the grotesque, the spritual/material and low /high culture. The author also examines Moodie’s vision, his personal universe and working methods, while describing the skin-like surfaces accentuated through the repetition of imagery and inclusion of objects such as rose petals. List of works. Biographical notes. 4 bibl. ref.
Rat kidney glutathione S-transferase 1 subunits have C-terminal truncations (1996)

Cytosolic glutathione S-transferases (GSTs) from rat kidneys were purified by a combination of glutathione and S-hexylglutathione affinity columns. The isolated GSTs were subjected to reverse-phase HPLC and electrospray MS analysis. The major GST isoenzymes expressed in kidney are subunits 1, 2, 7 and 8. GST 1',3 and 4 are expressed in minor amounts. GST 10 is barely detectable in the male kidney cytosol. The molecular masses of these rat kidney GST subunits were determined by MS. The values obtained for subunits 1', 2, 3, 4, 7, 8 and 10 are identical with those obtained for rat liver GSTs. Rat kidney GST 1 consists of three polypeptides, with molecular masses of 25517, 25372 and 24982 Da. Results from peptide mapping, MS and amino-acid-sequencing analyses indicate that the major components were generated by deleting the C-terminal phenylalanine (24982 Da) and the C-terminal IFKF tetrapeptide (25372 Da) from the GST 1 subunit, respectively. The 1-chloro-2,4-dinitrobenzene-conjugating and peroxidase activities of kidney GST 1 are substantially lower than for its counterpart from rat liver. In addition, rat kidney GST 1 has an arginine and a valine residue at positions 151 and 207 respectively. The results are in contradiction with the SWISS-PROT and GenBank rat liver GST 1 cDNA-sequencing data, which give a lysine and a methionine at the corresponding positions. Further analyses indicate that rat liver GST 1 also has a C-terminal phenylalanine deletion, and an arginine and a valine residue at positions 151 and 207 respectively. However, the C-terminal-tetrapeptide-deleted form was not observed for rat liver GST 1.
A High Efficiency Data Compression Scheme Based on Deletion of Bit-plain in Wireless Multimedia Sensor Networks (2013)

최근 무선 센서 네트워크는 멀티미디어 센서 모듈 기반의 고품질의 모니터링에 대한 요구가 증가하고 있다. 그러나 멀티미디어 데이터는 크기가 매우 크므로 데이터 전송 과정에서 특정 노드에 과도한 에너지 소모를 야기하여 전체 네트워크 수명이 감소하는 문제점이 있다. 이러한 문제점을 고려하여, 본 논문에서는 무선 멀티미디어 센서 네트워크에서 고효율 데이터 압축 기법을 제안한다. 제안하는 기법에서는 멀티미디어 데이터의 특성을 고려한 낮은 순위 비트 데이터 삭제 기반의 1단계 압축 및 중국인의 나머지 정리기반의 2단계 압축으로 구성된 다중 압축을 수행함으로써 데이터 크기를 감소시킨다. 제안하는 기법의 우수성을 보이기 위해 시뮬레이션을 통해 기존 압축기법과 성능을 비교한다. 성능평가 결과, 제안하는 기법은 기존 압축 기법에 비해 데이터 전송률이 평균 약 55% 감소하였으며, 노드 생존율은 16% 증가하였다. In recent years, the demands of multimedia data in wireless sensor networks have been significantly increased for the high-quality environment monitoring applications that utilize sensor nodes. However, since the amount of multimedia data is very large, the network lifetime is significantly reduced due to excessive energy consumption on particular nodes. To overcome this problem, in this paper, we propose a high efficiency data compression scheme in wireless multimedia sensor networks. The proposed scheme reduces the packet size by a multiple compression technique that consists of primary compression that deletes the lower priority bits considering characteristics of multimedia data and secondary compression based on Chinese Remainder Theorem. To show the superiority of our scheme, we compare it with the existing compression scheme. Our experimental results show that our proposed scheme reduces the amount of transmitted data by about 55% and increases network lifetime by about 16% over the existing scheme on average.