gebhart/patrepeval huggingface dataset:
A Determinative Scheme for the Fluorescent Plant Pathogenic Pseudomonads (1966)

S ummary . The differential value of 15 characteristics was studied for the determination of plant pathogens in the fluorescent group of the genus Pseudomonas. All but 2 of the 161 pathogenic cultures and the 15 nonpathogenic cultures examined could be placed in one of 5 groups on the basis of tests for: oxidase, potato soft rot, arginine dihydrolase, levan production and a hypersensitivity reaction in tobacco leaves. Tests for production of acid from sucrose, nitrate reductase and a lipase for margarine were useful as subsidiary determinants. Aesculin hydrolysis, gelatinase and tyrosinase tests, and the production of a blue fluorescent pigment were of little or no value at the group level, and hydrolysis of Tween 80 and the catalase reaction had no differential value. With the exception of Ps. tolaaii and two cultures of questionable pathogenicity, the pathogens studied could be separated readily from the few nonpathogens studied. A determinative scheme for plant pathogenic fluorescent pseudomonads is proposed to serve until the taxonomy of the group is better understood.
Multimodal Transfer Deep Learning with Applications in Audio-Visual Recognition (2014)

We propose a transfer deep learning (TDL) framework that can transfer the knowledge obtained from a single-modal neural network to a network with a different modality. Specifically, we show that we can leverage speech data to fine-tune the network trained for video recognition, given an initial set of audio-video parallel dataset within the same semantics. Our approach first learns the analogy-preserving embeddings between the abstract representations learned from intermediate layers of each network, allowing for semantics-level transfer between the source and target modalities. We then apply our neural network operation that fine-tunes the target network with the additional knowledge transferred from the source network, while keeping the topology of the target network unchanged. While we present an audio-visual recognition task as an application of our approach, our framework is flexible and thus can work with any multimodal dataset, or with any already-existing deep networks that share the common underlying semantics. In this work in progress report, we aim to provide comprehensive results of different configurations of the proposed approach on two widely used audio-visual datasets, and we discuss potential applications of the proposed approach.
L'obligation de vigilance à l'égard des atteintes à l'environnement (2011)

National audience
Perspectives of innovation development viewed by russian scientific and technical elite (2011)

The author highlights the problem of modernization of Russian society and gives an attempt to look at it through the eyes of those whose professional activity is directly connected to the production of new knowledge and creation of modern high technologies – representatives of scientific and technical elite of Russia. The article investigates the current state of Russia`s scientific potential, social base for modernization (groups and social strata which could become the driving force of the transition to the new model of development), the influence of different government structures on the modernization potential; factors that could improve the situation in Russian science and return its leading positions. The analysis is based on the assessment given by 170 experts that hold the leading positions in different spheres related to high technologies.
Characterization of an efficient high-gain Raman amplifier (1982)

Raman amplifiers have several important applications, such as efficient conversion of laser frequency, pulse compression, and brightness enhancement. We investigated in detail characteristics of a Raman amplifier which uses methane gas pumped by KrF laser radiation at 248.5 nm. A high-quality Stokes beam was generated and amplified in an amplifier with a large Fresnel number, efficiently depleting pump beams of poor spatial quality. This system has a potential for scaling up to energies needed for laser fusion experiments.
Past, present, and future of Bcr-Abl inhibitors: from chemical development to clinical efficacy (2018)

Bcr-Abl inhibitors paved the way of targeted therapy epoch. Imatinib was the first tyrosine kinase inhibitor to be discovered with high specificity for Bcr-Abl protein resulting from t(9, 22)-derived Philadelphia chromosome. Although the specific targeting of that oncoprotein, several Bcr-Abl-dependent and Bcr-Abl-independent mechanisms of resistance to imatinib arose after becoming first-line therapy in chronic myelogenous leukemia (CML) treatment.Consequently, new specific drugs, namely dasatinib, nilotinib, bosutinib, and ponatinib, were rationally designed and approved for clinic to override resistances. Imatinib fine mechanisms of action had been elucidated to rationally develop those second- and third-generation inhibitors. Crystallographic and structure-activity relationship analysis, jointly to clinical data, were pivotal to shed light on this topic. More recently, preclinical evidence on bafetinib, rebastinib, tozasertib, danusertib, HG-7-85-01, GNF-2, and 1,3,4-thiadiazole derivatives lay promising foundations for better inhibitors to be approved for clinic in the near future.Notably, structural mechanisms of action and drug design exemplified by Bcr-Abl inhibitors have broad relevance to both break through resistances in CML treatment and develop inhibitors against other kinases as targeted chemotherapeutics.
Natural killer cell neoplasms (2008)

Abstract Natural killer (NK) cell tumors are an uncommon and heterogeneous group of disorders. The World Health Organization (WHO) classified mature NK cell neoplasms into 2 types: 1) extranodal NK cell lymphoma, nasal type and 2) aggressive NK cell leukemia. The mature NK cell tumors are prevalent in Asia and Central and South America. These tumors show polymorphic neoplastic infiltrate with angioinvasion and/or angiodestruction, cytoplasmic azurophilic granules, CD2‐positive (CD2 + )/CD3‐negative (CD3 − )/cCD3ε + /CD56 + phenotype, and strong association with Epstein‐Barr virus (EBV). Loss of chromosomes 6q, 11q, 13q, and 17p are recurrent aberrations. Although blastic NK cell lymphoma, currently referred to as CD4 + /CD56 + hematodermic neoplasm, also was included in the NK cell lymphoma category in the WHO classification scheme, existing evidence indicates a plasmacytoid dendritic cell derivation as opposed to an NK cell origin. Recently, rare cases of CD56 + immature lymphoid tumors have been reported in the literature. These tumors are characterized by blastic appearance, CD3 − /CD4 − /CD56 + /CD13 − /CD33 − phenotype, T‐cell receptor and immunoglobulin genes in germline configuration, and no evidence of EBV, suggesting a true immature NK cell derivation. For this article, the authors reviewed the recent concepts and progress in clinicopathologic features, pathogenesis, genetic characteristics, diagnosis, differential diagnosis, treatment approaches, and outcomes of all subtypes of NK cell neoplasms. Cancer 2008. © 2008 American Cancer Society.
Synthesis of α-Amino Amides via <i>N</i>,<i>O</i>-Acetals Derived from Weinreb Amides (2009)

An easy and straightforward synthesis of alpha-amino amides via a base-mediated rearrangement of modified Weinreb amides into N,O-acetals is presented. Subsequent arylation, alkylation, alkenylation, or alkynylation of this intermediate affords the corresponding alpha-amino amides in excellent yields. Furthermore, a more generalized protocol for the alpha-arylation of Weinreb amides lacking an alpha-amino moiety is also discussed.
Evolutionary Selection Growth: Towards Template‐Insensitive Preparation of Single‐Crystal Layers (2012)

A method for growth of large-area, selectively defined, single-crystal semiconductor material on an amorphous template has been demonstrated. In two steps, the degrees of freedom in crystal orientation have been reduced by the principle of evolutionary selection, starting with the deposition of a textured aluminum nitride seed on SiO2, and the longitudinal growth of gallium nitride single crystals. This concept enables the integration of semiconductor materials with a new range of substrates. As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
Initial on-orbit results from the Compact Environmental Anomaly Sensor (CEASE) (2001)

The Compact Environmental Anomaly Sensor (CEASE) is an instrument designed to provide real-time space environment hazard warnings to the host spacecraft. In this paper, we report on the first year of on-orbit operation of this instrument and describe its performance with particular emphasis on its engineering, hazard-warning function.
Diazepam Attenuates Morphine Antinociception Test‐Dependently in Mice (1990)

The influence of diazepam on the antinociceptive effect of morphine was studied using four different nociceptive tests in mice. In the tail flick test, diazepam induced a dose-dependent reduction of the morphine effect, with an almost total reversed morphine effect following diazepam 2 mg/kg. The effect could not be explained by altered tail skin temperature or pharmacokinetic changes. Diazepam 1 mg/kg and higher induced sedation and significantly impaired the performance in a rotarod test, a dose of 0.5 mg/kg diazepam was therefore used in the other nociceptive tests. This dose of diazepam significantly attenuated the antinociceptive effect of morphine in the constant temperature hot plate test and the tail flick test. In the increasing temperature hot plate test and in the formalin test, no effect of diazepam on the nociceptive effect of morphine was observed. The results indicate that diazepam antagonizes the effect of morphine dependent upon the test employed. No antagonism could be observed in tests with a long-lasting stimulus, and a response integration probably at a rather high level in the CNS. In the two tests showing antagonism, the stimulus is more short-lasting, and at least for the tail flick test, the integration takes place at a lower level in the CNS.
Experimental investigation of a 2.5 centimeter diameter Kaufman microthruster (1973)

A 2.5-centimeter-diameter Kaufman electron bombardment microthruster was fabricated and tested. The microthruster design was based on the 15-centimeter-diameter SERT 2 and 5-centimeter-diameter Lewis experimental thruster designs. The microthruster with a two-grid system, operating at a net accelerating potential of 600 volts and an accelerator potential of 500 volts, produced a calculated 445 micronewton thrust when it was run with a 9-milliampere beam current. A glass grid was initially used in testing. Later a two-grid system was successfully incorporated. Both the propellant utilization efficiency and the total power efficiency were lower than for large-size advanced thrusters, as expected; but they were sufficiently high that 2.5-centimeter thrusters show promise for future space applications. Total power of the microthruster with an assumed 7-watt hollow-cathode neutralizer was less than 30 watts at a thrust level of 445 micronewton (100 Nu LBf). The hollow cathode was operated at zero tip heater power for power requirement tests.
Elongation factor Tu as a control gene for mRNA analysis of lung development and other differentiation and growth regulated systems (1993)

The analysis of steady state mRNA levels in cells or tissues that are undergoing growth and developmental changes can be problematic due to the lack of invariant control genes.Direct staining of agarose gels for 18s and 28s ribosomal RNAs is often used to control for loading errors.This approach does not control for transfer and hybridization artifacts.Several genes including actin, GAPDH, and B2 microglobulin have been used successfully as control genes.However, these genes are not always suitable controls when growth state is changing or limited
Processing and Properties of Natural Fiber-Reinforced Polymer Composite (2012)

A novel low cost polymer composite using brown grass flower broom reinforcement is prepared. The prepared polymer composite has the lowest porosity, homogeneous surface structure, and the greatest interface bonding. From the physico-mechanical characterization such as: hardness measurement, density measurement, void fraction or porosity measurement, and flexural strength measurement, it is found that the prepared composite is of light weight and high strength. Again, from dielectric behaviour of this polymer composite, it is found that this material has an efficiency that is considered as a high valued marketable product. As the composite is made using bio-materials from local resources, its cost is less compared to other polymer composites available today.
Studies of the leukemic cell associated antigen(s) in mice with myeloid leukemia (Graffi), using the immunoperoxidase techniques. (1979)

Theodore Roosevelt thanks J. A. Lindell for sending him a copy of a paper. Roosevelt found it very entertaining.
Differential Processing of Neuropeptides Influences<i>Drosophila</i>Heart Rate (1999)

Peptides that play critical physiological roles are often encoded in precursors that contain several structurally-related gene products. Differential processing of a precursor by cell-specific processing enzymes can yield multiple messengers with diverse distributions and activities. We have reported the isolation of SDNFMRFamide, DPKQDFMRFamide, and TPAEDFMRFamide from adult Drosophila melanogaster. The peptides are encoded in the FMRFamide gene and have a common C-terminal FMRFamide but different N-terminal extensions. In order to investigate the processing of the FMRFamide polypeptide protein precursor, we generated antisera to distinguish among the structurally-related neuropeptides. Utilizing a triple-label immunofluorescent protocol, we mapped the distribution of the peptides. Each peptide has a unique, non-overlapping cellular expression pattern in neural tissue suggesting that the precursor is differentially processed. In order to identify a biological activity of the peptides, we established an in vivo heart rate assay. SDNFMRFamide decreases heart rate but DPKQDFMRFamide and TPAEDFMRFamide do not, indicating that the N-terminal residues are critical for this activity. SDNFMRFamide immunoreactivity is present in the aorta, implying that SDNFMRFamide acts locally to affect heart rate; DPKQDFMRFamide and TPAEDFMRFamide antisera do not stain cardiac tissue. Our data support the conclusion that Drosophila contains cell-specific proteolytic enzymes to differentially process a polypeptide protein precursor resulting in unique expression patterns of structurally-related, yet functionally distinct neuropeptides.
Investigation of qualitative methods for diagnosis of poor bit performance using surface drilling parameters (2002)

Bit performance in deep shale when using water-based mud is typically poor. This study is part of a larger research project to improve that performance entitled "Automated Rig Controls for Improved Drilling Costs." The objective of the project is diagnosis of changes in drill bit performance to provide a logical basis for automating draw works control, maximizing bit performance, and reducing drilling costs. The specific goal of this study is a means to diagnose bit performance, specifically to identify bit balling and lithology changes, using real-time drilling data. The research began by identifying symptoms relating to specific causes of bit performance changes based on previously published research. Four published and six additional new potential parameters were identified for evaluation. Laboratory data was analyzed from both single cutter and full-scale tests to evaluate which diagnostic measures best indicated the causes of different or changing performance. Five of the diagnostic parameters were selected for further evaluation. An example set of field data was acquired that included both surface records of operational parameters and an electric log of the formations in a 2600 foot interval. Rate of penetration was estimated using Lubinski's method. Three published and two new diagnostic parameters were calculated for the entire interval. The sign, magnitude, and trend of these diagnostic parameters were compared to the changes evident in the data to establish the relationship between each diagnostic parameter, the lithology, and whether the bit was balled or drilling efficiently. As a result, a method for defining baseline values of each parameter, identifying lithology, and determining whether the severity of bit balling is constant, being reduced, or increasing is proposed and demonstrated. This method can potentially provide a basis for operational changes to improve bit performance, to help detect lithology changes, and to delineate bed boundaries more accurately.
<title>Automatic tracking of linear features on SPOT images using dynamic programming</title> (1999)

Detection of geographic elements on images is important in the perspective of adding new elements in geographic databases which are sometimes old and so, some elements are not represented. Our goal is to look for linear features like roads, rivers or railways on SPOT images with a resolution of 10 meters. Several methods allow this detection to be realized and may be classified in three categories: (1) Detection operators: the best known is the DUDA Road Operator which determine the belonging degree of a pixel to a linear feature from several 5 X 5 filters. Results are often unsatisfactory. It exists too the Infinite Size Exponential Filter (ISEF), which is a derivative filter and allows edge, valley or roof profile to be found on the image. It can be utilized as an additional information for others methods. (2) Structural tracking: from a starting point, an analysis in several directions is performed to determine the best next point (features may be: homogeneity of radiometry, contrast with environment, ...). From this new point and with an updated direction, the process goes on. Difficulty of these methods is the consideration of occlusions (bridges, tunnels, dense vegetation, ...). (3) Dynamic programming: F* algorithm and snakes are the best known. They allow a path with a minimal cost to be found in a search window. Occlusions are not a problem but two points or more near the searched linear feature must be known to define the window. The method described below is a mixture of structural tracking and dynamic programming (F* algorithm).
On some aspects of power system stabilizer blocking logic (2011)

This paper summarizes and discusses operational cases where the PSS blocking should be activated and also presents a different scenario in which the PSS should be blocked. More specifically, the paper is concerned with the operation of the PSS of a generator which is part of a power system experiencing a frequency stability problem caused by a severe real power unbalance. The paper discusses in detail the impact of the slow, but large-magnitude system frequency variations on the operation of PSS structures, which use the frequency signal for the synthesis of the stabilizing signal. It is demonstrated that under some circumstances PSS blocking during a frequency instability incident might not be an acceptable option. To address this case, a new PSS operational logic, referred to as `PSS de-sensitizing' is proposed. It is shown that with the PSS de-sensitizing it is possible to operate the PSS during all operational conditions without compromising the small-signal stability of the power system. The discussion is exemplified by realistic examples inspired by field experience.
Target tracking by neural network maneuver detection and input estimation (2002)

Although the Kalman filter is a powerful linear estimator for a continuous random process, it may fail to converge in the presence of sharp measurement discontinuities which may be caused by clutter or sudden target maneuvers. On the other hand, conventional models for the detection and compensation of target maneuvers are primarily based on a linear mapping of the innovation process onto an artificial noise process which is used to further adjust the covariance matrices of the Kalman filter. The nonlinear mapping capabilities of trained neural networks are employed to generate an estimate of the input noise through parallel processing of the Doppler information, the innovation process, and heading change estimate of a maneuvering target in clutter. It is shown that a neural network in conjunction with the Kalman filter can better resolve the bias caused by target maneuvers.
Hexahapto-chromium complexes of graphene: a theoretical study (2014)

Newly reported density functional M11-L is employed to elucidate the coordination of chromium fragments with oligoacenes as the model of graphene.
Luminescence properties of phosphors based on Tb3Al5O12 (TbAG) terbium-aluminum garnet (2009)

The processes of excitation energy transfer in phosphors based on single-crystal Tb3Al5O12:Ce (TbAG:Ce) and Tb3Al5O12:Ce,Eu (TbAG:Ce,Eu) garnet films have been investigated. These films are considered to be promising materials for screens for X-ray images and luminescence converters of blue LED radiation. The conditions for excitation energy transfer from the matrix (Tb3+ cations) to Ce3+ and Eu3+ ions in TbAG:Ce and TbAG:Ce,Eu phosphors have been analyzed in detail. It is established that a cascade process of excitation energy transfer from Tb3+ ions to Ce3+ and Eu3+ ions and from Ce3+ ions to Eu3+ ions is implemented in TbAG:Ce,Eu via dipole-dipole interaction and through the Tb3+ cation sublattice.
A modification of the mixing length approach to turbulent transport (1986)

It is known that the usual development of the mixing length approach to the transport of a passive physical quantity in a turbulent fluid is only valid if the proportional change in concentration of the quantity over a mixing length l is small. In the present paper we formulate a modification of the theory which is not subject to this constraint and proceed to apply it to various cases of interest. The results obtained can differ substantially from those given by the usual approach when the above criterion for the validity of the latter is not satisfied.
SI ME PERMITEN HABLAR (1979)

CON EL OBJETIVO DE LOGRAR LA INTEGRACION LATINOAMERICANA A TRAVES DE LA PALABRA, SUSANA ALEXANDER SE PRESENTA CON EL RECITAL SI ME PERMITEN HABLAR, EN VARIOS AUDITORIOS DE LA UNAM, EL ULTIMO HASTA EL MOMENTO FUE EL JUS SEMPER LOQUITUR DE LA FACULTAD DE DERECHO (FD). LA HISTORIA LATINOAMERICANA ES SENCILLA, SEGUN PALABRAS DE LA RECITADORA, CULTURAS GRANDES, DESCUBRIMIENTOS, UNA VIOLENTA CONQUISTA, MEZCLA DE RAZAS Y AMERICA SIGUE SIENDO TIERRA DE CRIOLLOS, MESTIZOS Y CONQUISTADORES. CON RESPECTO A LA ACTUACION EXPLICO QUE EL ARTISTA DEBE APROVECHAR EL MEDIO ESCENICO EN EL QUE ACTUA PARA PODER DAR UN MENSAJE POSITIVO AL PUBLICO, PORQUE ELLOS SE REFLEJAN EN NOSOTROS COMO EN UN ESPEJO. LAS PRESENTACIONES SON COORDINADAS POR LA DIRECCION GENERAL DE ACTIVIDADES SOCIOCULTURALES.