gebhart/patrepeval huggingface dataset:
ChemInform Abstract: Reaction of Dichlorocarbene with Some Organo‐Phosphorus Compounds in Low Coordination States (1993)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Identification of Optimal Control Compartments for Serial Near-Infrared Spectroscopy Assessment of Lower Extremity Compartmental Perfusion (2013)

Near-infrared spectroscopy (NIRS) has shown promise in detecting ischemic changes in acute compartment syndrome. The objectives of this study were to 1) assess the correlation in NIRS values between upper and lower extremity control sites for bilateral lower extremity trauma and 2) investigate the effect of skin pigmentation on NIRS values. Forty-four volunteers (14 male, 30 female) were monitored over separate 1-hour sessions. NIRS leads were placed over leg and upper extremity compartments. Colorimeters were used to document skin pigmentation. NIRS values between corresponding contralateral compartments were extremely well correlated (r = 0.76-0.90). Upper extremity NIRS values were correlated to leg values in the following order: volar (r = 0.65-0.71), dorsal (r = 0.36-0.60), and deltoid (r = 0.42-0.51). A negative correlation was observed between melanin and NIRS values. Analogous leg compartments are the optimal site of control for each other. The volar forearm may be the best upper extremity control. Skin pigmentation may affect absolute NIRS values.
Corrosion-Resistant, High-Strength Clad Metal System for Hydraulic Brake Line Tubing (1972)

<div class="htmlview paragraph">A new clad metal system has been developed as a material for hydraulic brake line tubing. The material consists of a 1008 LCS/304 SS/1008 LCS composite in the ratio 45%/10%/45%. Laboratory experimental tests, accelerated life tests, and field tests were performed on brake tubing formed from this material. The results show that the brazed and ternecoat low-carbon steel/stainless steel/low-carbon steel tubing has excellent corrosion resistance and high mechanical strength. The results are compared with those obtained with conventional brazed and ternecoat LCS brake tubing.</div>
Lysogenization by bacteriophage lambda. II. Identification of genes involved in the multiplicity dependent processes. (1974)

Summary We previously showed that, under conditions of rapid exponential growth, lysogenization of E. coli cells by phage λ requires that the cell is infected by at least 2 phages able to replicate their DNA, or 3 or 4 phages unable to replicate their DNA [ref. 4]. Since genes dealing with prophage integration appear not to be involved in these multiplicity dependent processes, a determination was made as to whether more than one copy of the genes involved in repressor synthesis or its activation are needed for lysogenization. The complementation patterns which we obtained indicate multiplicity effects involving gene cII (and, perhaps, cIII) in lysogenization by both phage able or unable to replicate. In the former case, we propose that cII protein (and, perhaps, cIII) both induces repressor synthesis and inhibits phage DNA replication. In lysogenization by phage unable to replicate, the data suggest that the expression of early phage genes and repressor synthesis in the course of lysogenization are mutually exclusive processes which do not take place on the same phage chromosome.
Identifying patients for blood conservation strategies (2002)

A simple algorithm using type of operation and haemoglobin concentration was effective in identifying patients likely to need perioperative homologous blood transfusion.
ChemInform Abstract: Dimeric Products from the Base‐Catalyzed Condensation of Benzaldehyde with 2,3‐Dihydro‐1H‐inden‐1‐one or 2‐(Phenylmethylene)‐2,3‐dihydro‐1H‐ inden‐1‐one. (1997)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Proportional Integral Observer Used in Recovery Design (1992)

The contribution of this paper is to formulate a design problem for Proportional Integral (PI) observer which facilitate their use in recovery design. It is shown that the PI-observes make it possible to obtain time recovery, i.e. exact recovery for t → ∞. An Loop Transfer Recovery (LTR) design metiod based on LQG design is derived which make it possible to obtain both time recovery and frequency-domain (normal) recovery at the same time. An example demonstrates this facility.
<i>N</i>-Alkylation of Amino Acid Esters Using Sodium Triacetoxyborohydride (1996)

Abstract N-Alkylation of amino acid esters by reductive amination using sodium cyanoborohydride may often be problematic. Sodium triacetoxyborohydride was found to be a convenient reagent for this transformation. This methodology was employed to alkylate various amino acid methyl esters.
Liquid fuels from the hydropyrolysis of biomass (1982)

A process designed to produce principally liquid fuel from Hawaiian biomass has been completed recently. This system consists of short residence-time pyrolysis of solids, entrained in a hydrogen atmosphere. This technique, which has been extensively developed at IGT for conversion of lignite, is termed HYFLEX. Following reaction at about 1100/sup 0/F (595/sup 0/C) and 200 psig (1.4 MPa), char and liquids are separated from the reactor outlet gas. Since fuel gas is not a desirable product at the location contemplated, the remaining gas is reformed with steam for production of a high-hydrogen-content gas which is recycled to the HYFLEX reactor. Bench-scale experiments were conducted with eucalyptus wood and leucaena wood feeds to establish data for process design. This paper describes the results of the wood tests and their comparison with similar data on peat. (JMT)
Structural Motif of the GCN4 DNA Binding Domain Characterized by Affinity Cleaving (1990)

The NH2-terminal locations of a dimer containing the DNA binding domain of the yeast transcriptional activator GCN4 have been mapped on the binding sites 5′-CTGACTAAT-3′ and 5′-ATGACTCTT-3′. Affinity cleaving was effected by synthetic GCN4 proteins with Fe⋅EDTA moieties at the NH 2 -terminus. Analysis of the DNA cleavage patterns for dimers of the Fe⋅EDTA-proteins corresponding to GCN4 residues 222 to 281 and 226 to 281 revealed that the NH 2 -termini were in the major groove nine to ten base pairs apart and were symmetrically displaced four to five base pairs from the central C of the recognition site. This result is consistent with the Y-shaped scissor grip-leucine zipper model recently proposed for a class of DNA binding proteins important in the regulation of gene expression.
Evaluation of data communication requirements for common demand response models (2015)

Demand response (DR) management is one of the key applications of future energy systems. Most of the corresponding models and algorithms require data communication between different smart grid network components to work efficiently. In this paper, 31 contributions from literature are evaluated with respect to their data communication requirements. Although the analyzed proposals on DR models do not specify detailed requirements on network architecture, communication protocols, or Quality of Service, our analysis has clearly shown which links are mandatory for all models. It has also been shown on which network parts measures to ensure security and privacy have to be implemented, especially when specific DR algorithms are used. DR proposals which function with a minimum of data communication could be identified.
Organic Chemistry and Medicinal Chemistry Based on .ALPHA.-Hydroxy-.BETA.-amino Acids (2005)

α-Hydroxy-β-amino acids are well known as inhibitory machinery for the development of protease inhibitors. In our ongoing efforts to develop effective aspartic protease inhibitors such as HIV-1 protease, malaria plasmepsin and human β-secretase inhibitors, the α-hydroxy-β-amino acids are also the critical core structures. In addition, the unique structure of these amino acids, in which three different functional groups, i.e. amino, hydroxyl and carboxyl groups, are located on the two adjacent asymmetric carbon atoms, also has interesting features to create new functional molecules useful in both organic chemistry and medicinal chemistry. In this article, organic and medicinal chemical applications based on the chemistry of α-hydroxy-β-amino acids will be presented, including 1) byproduction of homobislactone during the carboxyl group activation of N-protected-α-hydroxy-β-amino acids, 2) development of α-hydroxy-β-amino acid derived new solid-supported Evans' chiral auxiliary for asymmetric synthesis, 3) development of a novel and efficient method for the synthesis of difficult sequence-containing peptides, and 4) O-N intramolecular acyl migration of α-hydroxy-β-amino acids for the development of water-soluble prodrugs of taxoids (isotaxoids).
Disulfide bonding controls the processing of retroviral envelope glycoproteins. (1991)

The mitogenic membrane glycoprotein (gp55) encoded by Friend erythroleukemia virus is inefficiently processed from the rough endoplasmic reticulum (RER) and only 3-5% reaches plasma membranes. Because this processed component (gp55P) contains larger and more complex oligosaccharides, it can be separated from RER gp55. In nonreducing conditions, gp55P is a unique disulfide-bonded dimer, whereas RER gp55 consists of monomers and dimers with diverse intrachain and interchain disulfide bonds. This suggests that gp55 folds heterogeneously and that only one homodimer is competent for export from the RER. Pulse-chase analyses of gp55 components labeled with radioactive amino acids indicated that formation of diverse disulfide-bonded components occurred within minutes of polypeptide synthesis and that malfolded components did not later isomerize to generate dimers competent for export from the RER. Chemical studies suggested that all 12 cysteines of gp55 were oxidized within 5 min after synthesis of the protein. In contrast, the envelope glycoprotein precursor (gPr90) encoded by a replication-competent murine leukemia virus folds more homogeneously, and it is then processed and cleaved to form an extracellular glycoprotein gp70 plus a transmembrane protein p15E. The fully processed glycoprotein contains an unoxidized cysteine sulfhydryl that isomerizes reversibly with a disulfide bond that links gp70 to p15E. Consequently, only a proportion of gp70 and p15E is disulfide-bonded, and dissociation occurs when the environment becomes even slightly reducing. The gp55 glycoprotein appears to be an extreme example of protein malfolding associated with imprecise and irreversible disulfide bonding. We discuss evidence that folding inefficiencies are common for retroviral proteins that have newly evolving pathogenic functions.
The Adapter Protein ZIP Binds Grb14 and Regulates Its Inhibitory Action on Insulin Signaling by Recruiting Protein Kinase Cζ (2002)

Grb14 is a member of the Grb7 family of adapters and acts as a negative regulator of insulin-mediated signaling. Here we found that the protein kinase Czeta (PKCzeta) interacting protein, ZIP, interacted with Grb14. Coimmunoprecipitation experiments demonstrated that ZIP bound to both Grb14 and PKCzeta, thereby acting as a link in the assembly of a PKCzeta-ZIP-Grb14 heterotrimeric complex. Mapping studies indicated that ZIP interacted through its ZZ zinc finger domain with the phosphorylated insulin receptor interacting region (PIR) of Grb14. PKCzeta phosphorylated Grb14 under in vitro conditions and in CHO-IR cells as demonstrated by in vivo labeling experiments. Furthermore, Grb14 phosphorylation was increased under insulin stimulation, suggesting that the PKCzeta-ZIP-Grb14 complex is involved in insulin signaling. The PIR of Grb14, which also interacts with the catalytic domain of the insulin receptor (IR) and inhibits its activity, was preferentially phosphorylated by PKCzeta. Interestingly, the phosphorylation of Grb14 by PKCzeta increased its inhibitory effect on IR tyrosine kinase activity in vitro. The role of ZIP and Grb14 in insulin signaling was further investigated in vivo in Xenopus laevis oocytes. In this model, ZIP potentiated the inhibitory action of Grb14 on insulin-induced oocyte maturation. Importantly, this effect required the recruitment of PKCzeta and the phosphorylation of Grb14, providing in vivo evidences for a regulation of Grb14-inhibitory action by ZIP and PKCzeta. Together, these results suggest that Grb14, ZIP, and PKCzeta participate in a new feedback pathway of insulin signaling.
Beyond device mobility (2008)

Users, application services, single files and files collections, computers, detachable memory, distributed network storage -- this is far from being the comprehensive list of thinkable today networked objects. More importantly, all of these objects can be mobile on their own or in any combination and independently of each other. The technology around information distribution, sharing, and retrieval drives towards new businesses, use cases and life styles whereas mobility plays an ever increasing role. Does current Internet architecture ready for that? Doubtfully not! This talk aims at discussing challenges around highly distributed and highly dynamic networking environment demanding generic support for mobility and session management.
Longitudinal Circumferential Vibrations of Magnetostrictive Rings (1951)

Abstract : An experimental investigation of the longitudinal circumferential vibrations of magnetostrictive rings is the subject of this report. Two methods of exciting several orders of these modes of vibration by means of magnetostriction are described. Sensitivity curves and radiation patterns of experimental transducers operating in these modes are presented.
Compact, Rugged Temperature Recorder (1982)

Solid-state temperature recorder is compact, lightweight, and rugged. Records 2,048 temperature readings over period of up to nearly a year and retains them at least another 4 months using batteries. Battery-operated recorder has no moving parts--is completely solid-state electronic.
Enhancing SDN security by device fingerprinting (2017)

Software-defined Networking (SDN) provides an increased flexibility and cost savings by separating the data from the control plane. Despite these benefits, this separation also results in a greater attack surface as new devices and protocols are deployed. OpenFlow is one of these protocols and enables the communication between the switch and the controller. Ideally this connection takes place over an encrypted TLS channel, but as this feature is marked optional, it is not supported by all devices. This allows an attacker to eavesdrop and alter the communication, hence resulting in a comprised network. In this work, we demonstrate a new approach for authentication based on device fingerprinting to enhance the security in scenarios, where cryptographic mechanisms are unavailable.
Reading newspaper text (2002)

The authors describe a method for segmenting a newspaper page image into labeled macro components (blocks) and recognizing the content. Connected component analysis is used to segment a newspaper image into several rectangular blocks and to filter connected components into character and noncharacter components. Textural analysis is then used to classify the remaining noncharacter components into graphics and photographs. Experimental results indicate that these techniques work very well.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
A New Total Synthesis of Oxyterihanine (1987)

Abstraet4xyterihanine (I), a phenolic benzo[clphenanthridine alkaloid, was efficiently synthesized from the corresponding protoberberine 4 through C6-N bond cleavage and subsequent cyclization v i a the acetal ( 1 2 ) .
Assessment of Normal Variability in Peripheral Blood Gene Expression (2002)

Peripheral blood is representative of many systemic processes and is an ideal sample for expression profiling of diseases that have no known or accessible lesion. Peripheral blood is a complex mixture of cell types and some differences in peripheral blood gene expression may reflect the timing of sample collection rather than an underlying disease process. For this reason, it is important to assess study design factors that may cause variability in gene expression not related to what is being analyzed. Variation in the gene expression of circulating peripheral blood mononuclear cells (PBMCs) from three healthy volunteers sampled three times one day each week for one month was examined for 1,176 genes printed on filter arrays. Less than 1% of the genes showed any variation in expression that was related to the time of collection, and none of the changes were noted in more than one individual. These results suggest that observed variation was due to experimental variability.
Ink-dependent <italic>n</italic>-factors for the Yule-Nielsen modified spectral Neugebauer model (2010)

Different inks may have different mechanical and/or optical properties. Existing Yule-Nielsen modified Neugebauer spectral prediction models assume however that the inks forming a color halftone behave similarly, i.e. that a single n-factor can model the lateral propagation of light within the paper as well as non-uniformities of the ink dot thickness profiles. However, if the inks have very different optical or mechanical properties, each ink may be separately modeled with its specific n-factor. In order to predict the reflection spectrum of such color halftones, we extend the ink spreading enhanced Yule-Nielsen modified spectral Neugebauer (EYNSN) model by calculating for each halftone an optimal n-factor as an average of the ink specific n-factors weighted by a parabolic function of the ink surface coverages. We compare the prediction accuracies of the standard EYNSN model where each halftone is predicted by making use of one global n-factor with the predictions accuracies of the extended EYNSN model where each halftone is predicted with its corresponding optimal n-factor derived from the individual ink-specific n-factors. For inks having very different optical and/or mechanical properties, we observe an improvement of the prediction accuracies.
Celecoxib, a Cyclooxygenase-2 Inhibitor, Reduces Neointimal Hyperplasia Through Inhibition of Akt Signaling (2004)

Celecoxib is a potential inhibitor of neointimal formation by blocking injury-induced Akt activation. These findings suggest a potential use for celecoxib in the prevention of restenosis after angioplasty.
Clinical implications of the "Multicenter Automatic Defibrillator Implantation Trial" (MADIT) (1997)

Efficacious therapy for chronic coronary patients, known to be at high risk of sudden arrhythmic death, has been a long-lasting challenge for cardiologists. The "Multicenter Automatic Defibrillator Implantation Trial" (MADIT) has demonstrated in a prospective, randomized trial that such patients achieve 54% better survival (p < or = 0.009) when treated with implantable defibrillators (ICDs) compared to conventional pharmaceutical therapy-primarily amiodarone. The identification of these patients is well-defined, and patients with previous myocardial infarction fitting the appropriate risk profile as defined by MADIT (ejection.fraction < or = 0.35), non-sustained ventricular tachycardia should seriously be considered for prophylactic ICD implantation.
Managing Information for Mass Fatality Identification: Gene Code Forensics and the World Trade Center Disaster (2003)

Gene Codes established five goals: Identify individual remains Reunify partial remains so that they can be returned to families Collect and warehouse meta-data for administrative review of reference samples (antemortem victim materials, such as toothbrushes, razors etc.) Track samples among collaborating laboratories Create an information management system to report metrics and make problem resolution proposals to supervisors at the New York City Office of Chief Medical Examiner (OCME)
Equilibrium protection studies of the interaction of bovine glutamate dehydrogenase with purine nucleotide effectors (1975)

<P>Abstract copyright UK Data Service and data collection copyright owner.</P>The <i>Scottish Social Attitudes</i> (SSA) survey was launched by ScotCen Social Research (formerly the Scottish Centre for Social Research) in 1999, following the advent of devolution. Based on annual rounds of interviews of between 1,200 to 1,500 people drawn using probability sampling (based on a stratified, clustered sample), it aims to facilitate the study of public opinion and inform the development of public policy in Scotland, similar to the <i>British Social Attitudes</i> (BSA) series (held at the Archive under GN 33168). The SSA survey has been conducted annually each year since 1999, with the exception of 2008. The survey has a modular structure. In any one year it typically contains three to five modules, each containing 40 questions. Funding for its first two years came from the Economic and Social Research Council, while from 2001 onwards different bodies have funded individual modules each year. These bodies have included the Economic and Social Research Council, the Scottish Government and various charitable and grant awarding bodies, such as the Nuffield Foundation and Leverhulme Trust. <br> <br> Further information on the SSA and links to publications may be found on the ScotCen Social Research <a href="https://natcen.ac.uk/search?series%5B43%5D=43" title="Scottish Social Attitudes" target="_blank">Scottish Social Attitudes</a> webpages.<br> <br>
Chemistry, Biological and Pharmacological Properties of Medicinal Plants from the Americas (2018)

Lessons from natural medicines application of LC/MS and LC/NMR in the search for new bioactive compounds from plants of the Americas the quest for new biologically active natural products pharmacochemistry of new compounds from South American plant bioassay methods useful for activity-guided isolation of natural product cancer chemopreventive agents biodiversity conservation and drug development in Suriname antimicrobial activities of phytochemicals from British Columbian medicinal plants bioactive compounds from Panamanian plants bioactive natural products of medicinal and agrochemical interest from selected Mexican medicinal plants the Brazilian folk medicine programme to validate medicinal plants - a topic in new antihypersensitive drug research recent developments in the chemistry and pharmacology of boldo and boldine metabolic engineering - a strategy to improve plant secondary metabolite production.