gebhart/patrepeval huggingface dataset:
A nyaki ütőerek dissectiója – 19 eset retrospektív elemzése (2019)

Cervical artery dissection is a common cause of stroke in young adults. It might occur shortly after a forceful neck trauma or a minor injury. However, spontaneous dissection is also common, which is associated with genetic, anatomical or environmental risk factors. Cervical artery dissection can produce a broad spectrum of clinical presentation varying from local symptoms to focal neurological deficits determined by the arterial territory involved. Early recognition is important since immediate initiation of treatment can significantly improve patient outcomes. While clinical features may raise suspicion for dissection, the diagnosis has to be confirmed by neuroimaging findings. The purpose of this paper is to give an overview on cervical (carotid and vertebral) artery dissections while presenting 19 cases. During three years, we evaluated the clinical features, risk factors, diagnostic and therapeutic procedures of these patients admitted with extracranial artery dissection. The prognosis of the disease can vary, 42% of our patients became asymptomatic. Orv Hetil. 2019; 160(22): 861-868.
[Atypical case of bronchial carcinoid]. (1997)

This article illustrates problems in diagnosis and treatment of an atypical form of bronchial carcinoid. We described the case of a 49-year old man, exposed to granite dust and noise for 25 years who had suffered from frequent bronchitis inflammations and pneumonias for 5 years prior to the diagnosis. He was admitted to our clinic because of supposed occupational nature of hearing deficiency. Although a pneumoconiosis was excluded before the admission, we found clinical and X-ray features of the right lung emphysema with medium restrictive ventilation disturbances. Bronchoscopy was performed because of "bright" right lung and ventilation disturbances and it showed presence of the carcinoid. Unusual in this case were tiny anamnestical findings (mild dyspnea attacks after physical effort or nervousness) plus increasing frequency of reported from the childhood bronchitis and pneumonias and uncharacteristic "bright" right lung in X-ray. Therapeutical difficulties resulted from atypical histological form of the tumor, its diameter, polypous-infiltrative character, and inconvenient localization. In spite of late diagnosis of carcinoid and significant acceleration of respiratory decompensation symptoms after the diagnosis the attempt of surgical therapy was appropriate but unsuccessful. After the operation the patient was suffering long lasting lowering of arterial pressure (what was corrected with catecholamine infusions) probably as a result of serotonin secretion. However it was not established because of technical reasons.
What is cardiac distress and how should we measure it? (2018)

After cardiac events, rates of depression and anxiety of 20–30% have been reported, along with elevated rates of post-traumatic stress disorder and higher rates of suicide. As unresolved negative affect is associated with greater morbidity and mortality, attempts have been made to understand the complexity of emotional and psychological responses to cardiac events. Although many studies purport to measure ‘cardiac distress’, they are often limited by adopting a definition of distress as depression plus anxiety. Following the lead of the oncology and diabetes fields in the development of condition-specific distress measures, this article argues for a multidimensional approach to cardiac distress and its measurement; it builds on the concept of the ‘cardiac blues’, to show the importance of understanding and measuring how this transient phenomenon of adjustment can become a persistent negative state which challenges the ability to cope with living after a cardiac event.
Requirement of the calcineurin subunit gene <i>canB2</i> for indirect flight muscle formation in <i>Drosophila</i> (2003)

Calcineurin is a calcium-activated protein phosphatase involved in multiple aspects of cardiac and skeletal muscle development and disease. Genes encoding calcineurin subunit proteins are highly conserved among animal species. Toward the goal of identifying new calcineurin-interacting loci that function in myogenic processes, we expressed an activated form of mouse calcineurin A in Drosophila and screened for suppressors of the phosphatase-induced lethality. Here, we demonstrate that a mutation in the canB2 gene, which encodes a regulatory subunit of Drosophila calcineurin, can suppress a pupal developmental arrest phenotype to adult viability. As canB2 is an essential gene and rare homozygous escapers are flightless, we further analyzed canB2 expression and function in pupae and adults. The gene is expressed in the forming indirect flight muscles and central nervous system during pupal development. A canA gene is comparably expressed in these tissues. Consistent with the observed muscle expression, canB2 mutants exhibit severe defects in the organization of their indirect flight muscles, a phenotype that is likely caused by muscle hypercontractility. Together, these findings demonstrate a vital role for the phosphatase in this specific facet of Drosophila myogenesis and show conserved fly and vertebrate calcineurin genes contribute prominently to fundamental processes of muscle formation and function.
Evaluation of the standardization needs of microgrids technology (2015)

Microgrid has played a crucial role in solving problems caused by integration of distributed generation and therefore be comes an effective and efficient means for promoting renewable energy utilization and improving power supply reliability. This paper summarizes the key technologies and standardization needs for microgrid development and applications, based on the market needs and industry status. Some key features of a microgrid that distinguish it from traditional power grid and smart grid are de scribed. After review of the relevant activities currently under going in IEEE and IEC, recommendations for microgrid standardization based on the existing work are proposed.
BACE1 Overexpression Regulates Amyloid Precursor Protein Cleavage and Interaction with the ShcA Adapter (2004)

The amyloid precursor protein (APP) is a cell surface protein with a large extracellular N-terminal domain, a single transmembrane segment, and a short cytoplasmic tail. Its location and structural features are characteristic of a receptor for signal transduction. Yet, the physiological function of APP is unclear, although it is well documented that APP's proteolytic processing, through the formation of membrane-bound C-terminal fragments (CTFs) and of beta-amyloid peptides, likely influences the development of Alzheimer's disease (AD). There is evidence that BACE1 is the enzyme responsible for beta-site cleavage of the APP and for the generation of CTFs. BACE1 expression is upregulated in AD brain, and we have recently shown in human brain and in vitro that BACE product CTFs, when phosphorylated in tyrosine residues, interact with the adaptor proteins ShcA and Grb2, which usually are involved in signal transduction pathways. We investigated the interaction between ShcA, APP, and CTFs in the H4 human cell line that overexpresses BACE1 to clarify the significance of such interactions in vitro and for AD generation. Our result show that the APP, CTF, and ShcA interaction is induced only upon overexpression of BACE1 either transiently or in stable cell lines. In particular, although BACE1 drives the formation of C99 and C89 CTFs, only C99 interacts with the ShcA adaptor protein. Therefore, our data suggest that BACE1 activity influences APP processing and its intracellular signaling through the ShcA adaptor protein.
Managing bronze beetle <i>Eucolaspis brunnea</i> in organic apple orchards (2006)

Bronze beetle (Eucolaspsis brunnea) is threatening the viability of New Zealands organic apple industry This study investigated the efficacy of organic insecticides against bronze beetle trialled adult emergence traps measured fruit damage caused by adult feeding and sampled larvae in the soil Laboratory bioassays of ten organically acceptable insecticides failed to identify an effective product to control adult bronze beetle Emergence trapping on two orchards showed that bronze beetle emergence peaked during November Bronze beetle damage on cv Royal Gala apples was highly variable among the 12 orchards surveyed and ranged from 2 to 43 immediately before harvest Royal Gala apples had much more damage when inspected in field bins than cv Braeburn apples Soil sampling suggested that most bronze beetle larvae are found 51150 mm below the soil surface during autumn
Chemistry of heterocyclic compounds series. Part 141. Synthesis and characterization of novel palladium(II) cyclometalated complexes of 2-vinylpyridine derivatives (1990)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTChemistry of heterocyclic compounds series. Part 141. Synthesis and characterization of novel palladium(II) cyclometalated complexes of 2-vinylpyridine derivativesGeorge R. Newkome, Kevin J. Theriot, Barry K. Cheskin, David W. Evans, and Gregory R. BakerCite this: Organometallics 1990, 9, 5, 1375–1379Publication Date (Print):May 1, 1990Publication History Published online1 May 2002Published inissue 1 May 1990https://pubs.acs.org/doi/10.1021/om00119a003https://doi.org/10.1021/om00119a003research-articleACS PublicationsRequest reuse permissionsArticle Views237Altmetric-Citations24LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
High temperature automotive application: A study on fine pitch Au and Cu WB integrity vs. Ni thickness of Ni/Pd/Au bond pad on C90 low k wafer technology (2010)

For high temperature automotive application, IC products are required to pass stringent high temperature storage stress test (e.g. 5000hrs at 150 deg C), hence requires reliable wire bonds. Such requirement is especially challenging with fine pitch Au & Cu wire bond (e.g. bond pad pitch < 70um and bonded ball diameter < 58um), more-so on low k wafer technology with bond-over-active requirement.
Variation in carbon content and size in developing fruit of Actinidia deliciosa genotypes (2010)

This study identifies the developmental processes contributing to variation in green-fleshed kiwifruit (Actinidia deliciosa (A. Chev.) C.F. Liang et A.R. Ferguson var. deliciosa) fruit dry matter content (DM) and fresh weight (FW) by comparing genotypes with either high or low final DM. Results are compared with the model for fruit development, the tomato (Solanum lycopersicum L.). Differences in final composition were attributable to a higher rate of starch accumulation from 70 days after anthesis in high DM genotypes, with no other consistent differences in accumulation of soluble sugars or organic acids. High DM genotypes had 70% higher starch content and differed from low DM genotypes in the allocation of carbon between storage and other components. DM was negatively correlated with final fruit FW only in high DM genotypes, whereas starch was a constant proportion of dry weight (DW), suggesting a dilution effect rather than an interaction between fruit size and carbohydrate metabolism. Compared with tomato, the organic acids, particularly quinic acid, contributed more to estimated osmotic pressure during growth in FW than the soluble sugars, regardless of final composition or size. Seed mass per unit FW was highest in high DM genotypes, suggesting a previously unrecognised role for kiwifruit seeds in accumulation of carbohydrate by the pericarp. Anatomical comparisons also identified a role for differences in the packing of the two principal cell types, with an increased frequency of the larger cell type correlated with reduced DM. These genotypes demonstrate that kiwifruit differs from tomato in the role of starch as the principal stored carbohydrate, the reduced importance of dilution by growth in FW and the more minor role of the sugars compared with the organic acids during fruit development.
High-quality three-dimensional analysis for the morphological investigation of human fetal heart in the first and early second trimester (2009)

<sec><st>Background</st> To investigate the structure of the ex-vivo fetal heart a high-quality imaging modality is vital because its size, especially in early gestation, is too small to manipulate by hand. High resolution episcopic microscopy &lpar;HREM&rpar; is a new method for high-quality 3D reconstruction of fetal specimens. 3D images are created by the automatic capturing of over 1000 perfectly aligned tomographic slices. We report the preliminary results of HREM in human fetal hearts. <fig loc="float" id="HRT95S1htjun09toc2ab34f01"><no>Abstract 034 Figure 1.</no><link locator="34-f01"></fig> <fig loc="float" id="HRT95S1htjun09toc2ab34f02"><no>Abstract 034 Figure 2.</no><link locator="34-f02"></fig> </sec><sec><st>Methods</st> Following ethical approval, we collected heart tissue from singleton pregnancies who underwent surgical termination of pregnancy from 6 to 18 weeks. The hearts were embedded into plastic resin before automatic sectioning and digital capturing to create 3D images. </sec><sec><st>Results</st> We retrieved 36 fetal hearts &lpar;9–17 weeks of postmenstrual gestation&rpar; from 120 attempted collections. Twelve samples have been processed so far. It has been possible to create high-quality 3D images of the fetal heart &lpar;figs 1 and 2&rpar;. There were four morphological features characteristic of first/early second trimester human heart compared with the mouse or later human hearts. The atrial appendages are more prominent and the great arterial walls are thickened compared with the second trimester human heart. The ventricular arrangement is more spiral and coronary arteries are more prominent in the human compared with the same stage of the mouse heart. </sec><sec><st>Conclusions</st> HREM can produce detailed morphological 3D images of the human fetal heart in the first trimester. This technique may be useful in the assessment of hearts that develop abnormally during the maturation phase such as hypoplastic left or right heart syndrome. </sec>
Wire-Guide Manipulator For Automated Welding (1994)

Compact motor drive positions guide for welding filler wire. Drive part of automated wire feeder in partly or fully automated welding system. Drive unit contains three parallel subunits. Rotations of lead screws in three subunits coordinated to obtain desired motions in three degrees of freedom. Suitable for both variable-polarity plasma arc welding and gas/tungsten arc welding.
Asymmetric Synthesis of (−)-Anatoxin-a via an Asymmetric Cyclization Using a New Ligand for Pd-Catalyzed Alkylations (1999)

Palladium-catalyzed asymmetric allylic alkylations have been explored in the context of medium-sized ring substrates, intramolecular vs intermolecular processes involving attack on a formally meso π-allyl intermediate in the desymmetrization, and the presence of electron-withdrawing groups on the cationic π-allylpalladium intermediate. The synthesis of anatoxin-a, also known as the “very fast death factor”, raises all of these questions. Ligands derived from trans-1,2-diaminocyclohexane and 2-diphenylphosphinobenzoic acid effect asymmetric alkylations with an allyl substrate bearing an electron-withdrawing group. On the other hand, a new type of ligand wherein the diamine is derivatized with both 2-diphenylphosphinobenzoic acid and 2-picolinic acid was required to effect asymmetric cyclization to form the 9-azabicyclo[4.2.1]non-2-ene system. A total synthesis of anatoxin-a from 5-hydroxy-1,8-nonadiene employing a metathesis reaction to form the cycloheptene and a palladium-catalyzed asymmetric cyclization to form the bicyclic ring system is achieved in 15% overall yield.
The Origin and Development of the Upper Lateral Incisor and Premaxilla in Normal and Cleft Lip/Palate Monkeys Induced With Cyclophosphamide (2000)

Understanding the origin of the lateral incisor (the tooth closest to the cleft) and the shift after its formation provides clues to high incidence of malformations and ectopia of this incisor in cleft patients.
Synthesis of amino-sugar disaccharides (1966)

K. Heyns, R. Harrison, K. Propp and H. Paulsen, Chem. Commun. (London), 1966, 671 DOI: 10.1039/C19660000671
Absent Pulmonary Valve: Echocardiographic Features (1997)

Congenital absence of the pulmonary valve, a rare anomaly, is characterized by absent or rudimentary pulmonary valve, often with annular stenosis, and aneurysmal dilatation of the pulmonary arteries. This defect is most commonly an accompaniment of tetralogy of Fallot but occasionally occurs alone. Four patients with this abnormality were examined by two-dimensional echocardiography at the Mayo Clinic. Doppler echocardiography provided hemodynamic assessment of the magnitude of outflow obstruction and valve regurgitation. The two-dimensional echocardiographic and Doppler features of absent or rudimentary pulmonary valve provided diagnostic information sufficient to proceed directly to surgical correction.
Applicability of a clinical scoring criteria for disease severity of ß-thalassemia/hemoglobin E in Indonesia (2018)

Background: β-thalassemia/HbE presents with a variety of clinical symptoms, from asymptomatic to severe, requiring routine transfusion. However, there is currently no agreed classification system to stratify patients based on clinical severity of β-thalassemia/HbE in the Indonesian population. Thailand has already established a classification system, and this study aimed to identify the applicability of the Thailand clinical scoring criteria to determine the severity of β-thalassemia/HbE in the Indonesian population.Methods: This descriptive study was conducted by evaluating patients with β-thalassemia/HbE, who were classified into mild, moderate, or severe groups based on the Thailand clinical scoring criteria.Results: A total of 293 subjects with β-thalassemia/HbE were included. Based on this clinical scoring criteria, it was found that only 21.5% of patients were classified as mild, and the remaining 35.5% and 44% were classified as moderate and severe respectively. Approximately 68.2% of the subjects in the severe group received transfusion at <4 years old, while only 10% of those in the mild group were transfused at the same age. In the mild group, only 10% of the subjects underwent routine transfusion, compared to 98.4% of the subjects in the severe group. In addition, only 27% of the subjects in the mild group showed stunted growth, while that in the moderate and severe groups were 54.5% and 86.8%, respectively.Conclusion: Thailand clinical scoring criteria is able to determine the severity of Indonesia thalassemia patient which needs further management, i.e. transfusion and observation of stunted growth. This scoring system will help provide the provision of the most ideal management for the groups of patients based on their requirements.
Managing digital images with SEM viewer<sup>™</sup> (1994)

In 1992 Millipore's Corporate SEM Lab made the transition from conventional analog recording of images to digital acquisition and archival. Commonly requested images could be easily and reliably retrieved, without significant loss of image quality or resolution. In theory, digital images could be sent over a network to desktop PC's for review, (rather than producing hard copy of all images). Using established wide area network system, the scope of incorporating digital images significantly broadened. A significant barrier appeared in that the images were acquired using two different hardware/software packages, by two different SEMs (ISI DS130-C and ElectroScan ESEM). Although both generate TIFF images the "flavors" are somewhat different. The TIFF formats were incompatible because the tags used for magnification, micron bar, and descriptor line data were different. As a result, only the image itself generated from one program could be read by the other program, as with all available TIFF readers. Our dilemma was how to enable a single program to recognize and display all necessary information i.e., magnification, descriptor line, and the micron bar with the image.
LeProT1, a Transporter for Proline, Glycine Betaine, and g-Amino Butyric Acid in Tomato Pollen (1999)

Rainer Schwacke, Silke Grallath, Kevin E. Breitkreuz, Elke Stransky, Harald Stransky, Wolf B. Frommer, Doris Rentsch, LeProT1, a Transporter for Proline, Glycine Betaine, and γ-Amino Butyric Acid in Tomato Pollen, The Plant Cell, Vol. 11, No. 3 (Mar., 1999), pp. 377-391
Model reduction and energy function analysis of power systems using singular perturbation techniques (1986)

This paper reviews some recent results in applying singular perturbation theory to obtain simplified power system models for stability analysis and control design. The topics include synchronous machine modeling, slow coherency and dynamic equivalencing of large power networks, and transient stability analysis using direct methods. The objective is to introduce power system engineers to singular perturbation methods as a tool for providing additional insights into power system dynamics of different time scales and for analytically deriving reduced models.