gebhart/patrepeval huggingface dataset:
Behavior modeling of object-oriented distributed systems (2002)

The object oriented approach has emerged as the dominant perspective of software engineering research. Object oriented models provide a powerful tool for specifying requirements and developing solutions of real world problems. Although a wide variety of constructs have been proposed in the literature for object oriented modeling, there has not been much work on extending these models for distributed applications. The paper identifies the requirements and issues of modeling the behavior of an object oriented distributed system and presents an analysis of the behavior modeling techniques. We propose a unifying framework called hierarchical sequences of events, for distributed behavior modeling. Our approach is to investigate the requirements of distributed applications and enrich existing object oriented models with structural end behavior modeling primitives and constructs for distributed systems. More specifically, we identify new attributes and properties of individual objects and extend the existing event based behavior modeling constructs to accommodate the modeling requirements of distributed systems.
Robust Detection of Corners and Corner-line Links in Images (2010)

We define corner points in an image as the intersections among detected straight line segments, and propose an algorithm that detects corners from such a definition. Our corner detection algorithm CLDC then makes use of the LDC (Line Detection using Contours) algorithm from, which outputs the list of all detected line segments together with their endpoints. Each line segment is extended in a post-processing step. CLDC (Corners from LDC) then finds corners in O((n + I)log n) time, where n and I are the number of endpoints the intersections of line segments, respectively. Detected corners are linked via line segments that define them. Such an output of the corner detection algorithm is a novel concept. The algorithm is comparable in time complexity with other algorithms, while providing more information about the line segments in the image. CLDC is robust to image transformations, such as rotation and translations. Our CLDC is compared to some existing algorithm, and its advantages are demonstrated.
QBROKAGE: A Genetic Approach for QoS Cloud Brokering (2014)

The broad diffusion of Cloud Computing has fostered the proliferation of a large number of cloud computing providers. The need of Cloud Brokers arises for helping consumers in discovering, considering and comparing services with different capabilities and offered by different providers. Also, consuming services exposed by different providers, when possible, may alleviate the vendor lock-in. While it can be straightforward to choose the best provider when deploying small and homogeneous applications, things get harder if the size and complexity of applications grow up. In this paper we propose a genetic approach for Cloud Brokering, focusing on finding Infrastructure-as-a-Service (IaaS) resources for satisfying Quality of Service (QoS) requirements of applications. We performed a set of experiments with an implementation of such broker. Results show that our broker can find near-optimal solutions even when dealing with hundreds of providers, trying at the same time to mitigate the vendor lock-in.
Transforming Growth Factor-β (TGFβ) Receptors I/II Differentially Regulate TGFβ1 and IGF-Binding Protein-3 Mitogenic Effects in the Human Placenta (2010)

Maternal IGFs regulate cytotrophoblast proliferation and, thereby, placental growth and function. IGF bioavailability is controlled by IGF-binding proteins (IGFBPs); in placenta, IGFBP-3 is particularly abundant. In other systems, IGFBP-3 can regulate cellular events independently of IGFs; these effects are thought to be mediated by TGFbeta receptors (TbetaR). We have examined IGFBP-3 regulation of IGF-dependent and -independent cytotrophoblast proliferation in first-trimester placental explants and the role of TbetaRII in mediating these effects. In the presence of IGFBP-3 (50 nm), IGF-induced (10 nm) proliferation (monitored by immunohistochemical analysis of Ki67 expression and bromodeoxyuridine incorporation) was significantly reduced (P < 0.05). IGFBP-3 also reduced basal proliferation independently of IGF receptor signaling. Immunohistochemical analysis demonstrated that TGFbeta signaling molecules [TGFbeta receptor I (TbetaRI), TbetaRII, TbetaRV, Smad-2, and ERK] are expressed in syncytium and/or cytotrophoblast. TGFbeta1 (10 ng/ml) enhanced cytotrophoblast proliferation and activated both Smad-2 and ERK-1/2, whereas IGFBP-3 activated only Smad-2. The function of both TGFbeta1 and IGFBP-3 was attenuated by a TbetaRII function-blocking antibody and by small interfering RNA-mediated knockdown of TbetaRII (P < 0.05); this was accompanied by a reduction in Smad-2 activation. This study demonstrates that both TGFbeta1 and IGFBP-3 signal through TbetaRI/II to influence human cytotrophoblast proliferation. However, downstream pathways are distinct, because IGFBP-3 acts only through Smad-2, whereas TGFbeta1 also phosphorylates ERK, resulting in opposite effects on cytotrophoblast proliferation. The effects of maternal growth signals on placental growth and function therefore depend on the balance of ligands, receptors, and signaling molecules at the syncytiotrophoblast surface. Therapeutic manipulation of this balance might offer a strategy to optimize placental development and pregnancy outcome.
Supersonic jet epitaxy of single crystalline cubic SiC thin films on Si substrates from t-Butyldimethylsilane (1998)

Cubic SiC thin films have been grown by supersonic jet epitaxy (SJE) using the single molecular precursor t-butyldimethylsilane (TBDMS), (CH3)3C–SiH(CH3)2. Single crystal cubic SiC thin films were grown on both carburized and uncarburized Si(100) at a temperature of 830°C. Highly oriented cubic SiC(111) thin films were obtained on carburized and uncarburized Si(111) substrates at 830°C. This growth temperature is much lower than conventional CVD growth temperatures. It is believed that this is the first report of SiC growth using t-butyldimethylsilane.
Characteristics of <i>Agrobacterium tumefaciens</i> Auxotrophic Mutant Infectivity (1966)

Lippincott, Barbara B. (Northwestern University, Evanston, Ill.), and James A. Lippincott. Characteristics of Agrobacterium tumefaciens auxotrophic mutant infectivity. J. Bacteriol. 92:937-945. 166.-Mutants of Agrobacterium tumefaciens auxotrophic for adenine, methionine, or asparagine are less infectious than the wild-type strain B6 from which they were derived and show increased infectivity on pinto bean leaves when the specific compounds required for growth of the mutants are added to the infected leaf. Reversion to a prototrophic form of nutrition is accompanied by increased infectivity. Tumors initiated by these auxotrophic mutants are shown to arise only at large wound sites where nutritional conditions may be less restricting. The data indicate that, after inoculation, the bacteria pass through a phase in which host-supplied nutrients are utilized for the production of one or more factors necessary for successful tumor initiation.
A Mutual Remote Password Authentication Scheme Based on the RSA System of Smart Card (2004)

This paper presents a mutual remote password authentication scheme based on the RSA system of smart card. Compared with other schemes, such as ChangLiao Scheme and so on, this scheme has some important merits which include: (1) clients can freely choose their passwords; (2) it provides mutual authentication between the client and the server; (3) while it is based on the RSA system, its realization is simple and reliable.
Ovulation Induction in Polycystic Ovary Syndrome (2010)

These guidelines have been reviewed and approved by the Reproductive Endocrinology and Infertility Committee of the SOGC.
Improving CC-NUMA performance using Instruction-based Prediction (1999)

We propose Instruction-based Prediction as a means to optimize directory based cache coherent NUMA shared memory. Instruction-based prediction is based on observing the behavior of load and store instructions in relation to coherent events and predicting their future behavior. Although this technique is well established in the uniprocessor world, it has not been widely applied for optimizing transparent shared memory. Typically, in this environment, prediction is based on data block access history (address based prediction) in the form of adaptive cache coherence protocols. The advantage of instruction-based prediction is that it requires few hardware resources in the form of small prediction structures per node to match (or exceed) the performance of address based prediction. To show the potential of instruction-based prediction we propose and evaluate three different optimizations: i) a migratory sharing optimization, ii) a wide sharing optimization, and iii) a producer consumer optimization based on speculative execution. With execution driven simulation and a set of nine benchmarks we show that i) for the first two optimizations, instruction-based prediction, using few predictor entries per node, outpaces address based schemes, and (ii) for the producer consumer optimization which uses speculative execution, low mis speculation rates show promise for performance improvements.
A low cost configuration management database using commercial off the shelf (COTS) open database compliant (ODBC) software [for active array measurement test bed] (1999)

A sophisticated low-cost Configuration Management Database (CMD) has been developed for the Active Array Measurement Test Bed (AAMTB) at the Crane Division, Naval Surface Warfare Center, Crane Indiana. By choosing three flexible COTS programs that feature object-oriented models, a common programming language, and ODBC compliance, the software development and project cost was minimized. This paper describes how the database provides recording and retrieval of comprehensive hardware and software configurations of measurement test scans. Details of our database structure, including its advantages and limitations are also presented.
Are Companies Actually Using Secure Development Life Cycles? (2010)

As threats to applications have increased, developers have begun including security in their software design. Secure development life cycles are methodologies for accomplishing this, but are companies actually using SDLs?
Organocatalytic regioselective Michael additions of cyclic enones via asymmetric phase transfer catalysis (2006)

Cyclohexanone and cycloheptanone can be enantioselectively functionalized in the 3-position with up to 92% ee and 87% ee, respectively, by the base-promoted dimerization of the corresponding enones using 3,4,5-tribenzyloxybenzyl cinchoninium bromide, as a new effective catalyst.
Reaction of carbethoxynitrene with allenes (1975)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTReaction of carbethoxynitrene with allenesElena M. Bingham and John C. GilbertCite this: J. Org. Chem. 1975, 40, 2, 224–228Publication Date (Print):January 1, 1975Publication History Published online1 May 2002Published inissue 1 January 1975https://pubs.acs.org/doi/10.1021/jo00890a016https://doi.org/10.1021/jo00890a016research-articleACS PublicationsRequest reuse permissionsArticle Views226Altmetric-Citations35LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
From the past to the future of therapeutic orthoses for upper limbs rehabilitation (2018)

Introduction The expansion of assistive technologies has been increasing significantly, involving almost all the daily activities, performed by disabled people. One of the highlights to be mentioned is the robotic orthoses, which are being used to amplify movements, to replace amputated limbs, and for a variety of rehabilitation therapies, among others. This study aims to present a review about upper limbs’ orthoses, discussing their weaknesses, potentialities, and pointing out for future perspectives under the motor rehabilitation. Methods For this research, it had been identified 161 papers, based on the bibliographic bases from IEEE and Science Direct, which were filtered by the keywords orthoses, hand, upper-limbs and technology. After the appropriate exclusions, 22 papers were analyzed. Results This review indicates that most of the orthoses have been developed for rehabilitation therapies to be employed by people who have suffered stroke, cerebral palsy or spinal cord injury. This research summarized that the upper limbs movements are effectively produced by electric or pneumatic actuators, having a variety of degrees of freedom. Conclusion This review has shown that, although there are many orthoses styles, ranging from electric to pneumatic actuators; also there are some technical restrictions that prevent their use by most people. However, upper limb orthoses seem to be a great solution for the rehabilitation of people who have suffered a stroke.
[Conditionally replicative adenoviruses: a second wind for cancer gene therapy]. (2003)

Cancer gene therapy has offered many hopes but its first use in humans revealed some pitfalls and at least three main problems: lack of efficacy and specificity of current vectors to deliver therapeutic genes, poor diffusion of the therapeutic effects inside the tumor (absence of bystander effect), poor distribution of the vectors injected inside the tissue. To address some of these issues, several teams have developed tumor selective replicating adenoviruses, some of them being already in the clinic. First results are promising but complementary studies are needed to define if these agents will take place in the therapeutic armentorium against cancer.
Separate compilation in CHIPSY (1989)

This paper describes a practical implementation scheme for separate compilation of strongly typed high-level languages. The scheme provides full inter-module type checking, while limiting the problems of “big inhale” and most redundant recompilations by employing smart recompilation at reasonable cost. It also provides type-safe link-time substitution of module variants.
A Multilayered Audiovisual Streaming System Using the Network Bandwidth Adaptation and the Two-Phase Synchronization (2009)

Synchronous audiovisual streaming and playout are two of the major issues in the multimedia communication network. However, the past corresponding researches of media synchronization mainly focused on the mono-quality and single-layer (nonscalable) audiovisual data. To overcome challenges of ubiquitous multimedia streaming, a scalable audiovisual coder that can provide flexible scalabilities and adaptive streaming control to adapt to complicated network situations are both required. This paper proposes a multilayered audiovisual streaming scheme to deliver layered audiovisual data synchronously, which is called ML-AVSS. Fine-granular scalability (FGS) and bit-sliced arithmetic coding (BSAC) techniques are used to segment video and audio data into one base-layer and multiple enhancement-layer bitstreams. With advantages of audiovisual layer coding, a de-jitter procedure, a conditional retransmission mechanism and a playout synchronization mechanism are designed to transmit hybrid multilayered audiovisual bitstreams in consideration of the result of a network bandwidth adaptation and the distinct decoding time-complexity. Experimental results show that the proposed ML-AVSS is a feasible streaming scheme to overcome challenges of ubiquitous multimedia streaming, e.g., constrained channel bandwidth, quality degradation, unsmooth playout, etc.
Hybrid Molecular Materials Based on Covalently Linked Inorganic Polyoxometalates and Organic Conjugated Systems We thank the University of Missouri-Kansas City and Research Corporation for supporting this work. (2001)

The Mo≡N bond is conjugated with the organic segment in the novel molecular organic-inorganic hybrid materials that have been obtained by Pd-catalyzed coupling of an iodo-functionalized hexamolybdate anion and an alkyne (see scheme; Ar=4-methylphenyl,3-5-di(tert-butyl)phenyl). The interaction between the polyoxometalate cluster and the organic conjugated system is particularly apparent from the strong red-shifted absorption in the UV/Vis spectrum.
StyA1 and StyA2B from <i>Rhodococcus opacus</i> 1CP: a Multifunctional Styrene Monooxygenase System (2010)

Two-component flavoprotein monooxygenases are emerging biocatalysts that generally consist of a monooxygenase and a reductase component. Here we show that Rhodococcus opacus 1CP encodes a multifunctional enantioselective flavoprotein monooxygenase system composed of a single styrene monooxygenase (SMO) (StyA1) and another styrene monooxygenase fused to an NADH-flavin oxidoreductase (StyA2B). StyA1 and StyA2B convert styrene and chemical analogues to the corresponding epoxides at the expense of FADH2 provided from StyA2B. The StyA1/StyA2B system presents the highest monooxygenase activity in an equimolar ratio of StyA1 and StyA2B, indicating (transient) protein complex formation. StyA1 is also active when FADH2 is supplied by StyB from Pseudomonas sp. VLB120 or PheA2 from Rhodococcus opacus 1CP. However, in both cases the reductase produces an excess of FADH2, resulting in a high waste of NADH. The epoxidation rate of StyA1 heavily depends on the type of reductase. This supports that the FADH2-induced activation of StyA1 requires interprotein communication. We conclude that the StyA1/StyA2B system represents a novel type of multifunctional flavoprotein monooxygenase. Its unique mechanism of cofactor utilization provides new opportunities for biotechnological applications and is highly relevant from a structural and evolutionary point of view.
All through the night (2001)

It was non-stop action when Victoria Reading shadowed a hospital night co-ordinator
Neurochemical and receptor theories of depression. (1989)

The neurochemical and receptor theories relate depression to deficient neurotransmission at critical sites in the brain. While this concept has generated a number of theories of depression over the years, the research findings do not fully support any single theory in its entirety. Several issues thus remain controversial or inconclusive. For instance, the monoamine deficit theory is supported by low urinary MHPG in some forms of bipolar, but not unipolar depression. Cerebrospinal fluid MHPG and 5-HIAA studies are inconclusive. Amine metabolite research is also limited in scope because the information derived pertains to pre-synaptic and synaptic events and ignores post-synaptic events. Receptor research, which includes study of both pre-and post-synaptic sites, suggests supersensitivity of Beta-adrenergic receptors in depression. But this research is criticized because it is mostly animal based. Also, the findings of low melatonin in depression contradict the supersensitivity-hypothesis. Abnormally low post-synaptic alpha-2 adrenoceptors is indicated by findings of an attenuated GH response to clonidine. But abnormality of pre-synaptic alpha-2 adrenoceptor functions has not been demonstrated conclusively. Recent findings in depression suggest a dysregulation in the dynamic and interactive relationship between neurotransmitters and receptors. Accordingly, a comprehensive view of the abnormalities of the various neurotransmitter systems in depression requires studies which investigate pre- and post-synaptic events simultaneously, preferably during illness and remission.
Bluetooth enables in-door mobile location services (2004)

Several technologies can be applied to enable mobile location services, but most of them suffer from limited accuracy and availability. GPS can solve the problem of determining the location of users in most outdoor situations, but an end-user position inside a building cannot be pinpointed. Other mobile location techniques can also provide the user's position, but the accuracy is rather low. In order to improve the accuracy and make location-based services really attractive, existing approaches must be supplemented by new technologies. Wireless short-range technologies like Bluetooth could be candidates for solving these problems. This paper shows that Bluetooth can act as a key enabler of mobile location services in an in-door environment. The advantage of Bluetooth technology is, that it can provide rather precise location data inside a building or hotspot area, while the Bluetooth terminal is connected to the network. Hence, the users are able to obtain more detailed guidance and information on their sites of interest such as department stores, airports and other public areas.
Transforming Standard Process Models to Decentralized Autonomous Entities. (2010)

Abstract. Today, in state of the art process engine architectures, pro-cess models are executed by a central orchestrator (i.e. one per process). There are however a lot of drawbacks in using a central orchestrator, including a single point of failure and performance degradation. Decen-tralization algorithms that distribute the workload of the central orches-trator exist, but the result still suffers from a tight coupling between the different decentralized orchestrators and therefore has a decreased scalability. In this paper, we show practical transformations to decen-tralize a process model into autonomous, independent process engines. This solves the fundamental problems of the classical decentralization al-gorithms, increases the availability of the global process flow and makes it easier to re-specify and redeploy process models. 1
Seen Elsewhere (1984)

“Seen Elsewhere” consists of digests of articles on the application and implementation of management science seen in other publications. —“Achieving the potential of decision support systems” (Journal of Business Strategy, Vol. 3, No. 3, Winter 1983, pp. 84–90) by William R. King (University of Pittsburgh).