gebhart/patrepeval huggingface dataset:
Potencial antimicrobiano e alelopático das amidas isoladas do extrato das raízes de Ottonia martiana Miq. (2006)

<abstract language="eng">Two amides, piperovatine and isopiperlonguminine, were isolated from the roots of Ottonia martiana Miq., a herbaceous shrub commonly used in folk medicine in the treatment of toothache. The crude extract (CE) and isolated compounds were submitted to bioautography and allelopathic assay. The bioautograms allowed the detection of compounds with antibacterial activity and the identification of the bioactive substance piperovatine. The CE and amides exhibited an allelopathic effect on Lactuca sativa (lettuce) seedling growth but did not affect the seeds' germinability.
New perfluoropolyether soft segment containing polyurethanes (1995)

Abstract New segmented polyurethanes (FPU) with perfluoropolyether (PFPE) blocks have been synthesized by a two‐step process. In the first step, a fluorinated isocyanate end‐capped prepolymer has been obtained by reaction of a fluorinated macrodiol with alicyclic diisocyanates in the presence of solvent. The following chain extension has been carried out by reaction of the prepolymer with short hydrogenated polyols giving a polymeric matrix. Tensile properties, dynamical–mechanical (DMA), and calorimetric (DSC) analyses have been evaluated, and relationships between chemical structure and final properties are established. These polymers show unusual low‐temperature elastomeric behavior, due to the low glass transition ( T g ) of the continuous fluorinated phase. In general, with respect to traditional polyurethanes (HPU), thermal stability and chemical resistance are strongly improved by the effect of the highly inert fluorinated chains. © 1995 John Wiley & Sons, Inc.
<title>Bridge monitoring by fiber optic deformation sensors: design, emplacement, and results</title> (1996)

In 1995, our laboratory fitted a highway bridge near Lausanne (Switzerland) with low- coherence fiber optic deformation sensors. The engineers, who had designed the steel-concrete composite bridge, were interested in the strain distribution inside the concrete slab and in the effects induced by the concrete shrinkage. More than 30 fiber optic deformation sensors, a few vibrating string deformation sensors, thermoelectric couples as well as resistive strain gages were installed in the concrete deck and on the steel girders of this bridge. Three phases of the bridge life were monitored: concreting and thermal shrinkage, load test with heavy trucks and long term deformations. This contribution presents the fiber optic sensor design, the installation technique and the preliminary results obtained on this bridge.
Studies on the intramolecular addition of vinyl nitrenes to olefins (1978)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTStudies on the intramolecular addition of vinyl nitrenes to olefinsAlbert Padwa and Per H. J. CarlsenCite this: J. Org. Chem. 1978, 43, 10, 2029–2037Publication Date (Print):May 1, 1978Publication History Published online1 May 2002Published inissue 1 May 1978https://pubs.acs.org/doi/10.1021/jo00404a042https://doi.org/10.1021/jo00404a042research-articleACS PublicationsRequest reuse permissionsArticle Views377Altmetric-Citations30LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Temporal effects of cell adhesion on mechanical characteristics of the single chondrocyte (2002)

Cell adhesion to material surfaces is a fundamental phenomenon in tissue response to implanted devices, and an important consideration in tissue engineering. For example, elucidation of phenomena associated with adhesion of chondrocytes to biomaterials is critical in addressing the difficult problem of articular cartilage regeneration. The first objective of this study was to measure the mechanical adhesiveness characteristics of individual rabbit articular chondrocytes as a function of seeding time to provide further understanding of the cell adhesion process. The second objective was to quantify the force required to separate the plasma membrane from the underlying cytoskeleton as a function of seeding time. After culturing chondrocytes on glass coverslips for 1, 2, 4, 6 h, two biomechanical tests were performed on single chondrocytes: (i) mechanical adhesiveness measurement by the cytodetacher; and (ii) plasma membrane tether formation force measurement by optical tweezers. Cell mechanical adhesiveness increased from 231+/-149 Pa at 1 h to 1085+/-211 Pa at 6 h. The cell contact area with the substrata increased from 161+/-52 microm(2) at 1 h to 369+/-105 microm(2) at 6 h. The tether formation force increased from 232+/-23 pN at 1 h to 591+/-17 pN at 6 h. Moreover, fluorescence staining by rhodamine-phalloidin demonstrated the process of actin spreading within the cytoskeleton from 0.5 to 6 h and allowed for measurement of cell height which was found to decrease from 12.3+/-2.9 microm at 0.5 h to 6.2+/-0.9 microm at 6 h.
Study on High Speed Machining (9) (1956)

It was reported by the previous papers that the tool-chip contact area is a controlling factor in metal machining. One of the most typical examples of this effect is revealed in high speed machining.The main object of this experiment is to find out the reason why the machining characteristics are such improved that the shear angle and chip thickness ratio increase, and the cutting force decreases generally, when cutting speed is raised up. By such a special type of machining test that the shear angle was always kept constant, it was proved that the shear strain in the shear plane is localized into a narrow zone as the cutting speed increases. This is because that the plastic deformation in the shear zone occurs more adiabatically at higher cutting speeds as C. Zener made it sure in his punch test of rather plastic materials. Anyhow this tendency makes the tool-chip contact area smaller at higher cutting speeds, which results into a larger shear angle, that is, better machining characteristics, to balance the cutting force on the rake face, according to the theory described by the previous reports.Here also so called the coefficient of friction in metal cutting has been proved to be a poor index of the machining characteristics, whereas the tool-chip contact area has been demonstrated to play a very important role in the mechanism of high speed machining as well as for the analysis of general metal machining.
On Flat versus Hierarchical Classification in Large-Scale Taxonomies (2012)

International audience
Enhanced ablation efficiency for silicon by femtosecond laser microprocessing with GHz bursts in MHz bursts(BiBurst) (2021)

Abstract Ultrashort laser pulses confine material processing to the laser-irradiated area by suppressing heat diffusion, resulting in precise ablation in diverse materials. However, challenges occur when high speed material removal and higher ablation efficiencies are required. Ultrafast burst mode laser ablation has been proposed as a successful method to overcome these limitations. Following this approach, we studied the influence of combining GHz bursts in MHz bursts, known as BiBurst mode, on ablation efficiency of silicon. BiBurst mode used in this study consists of multiple bursts happening at a repetition rate of 64 MHz, each of which contains multiple pulses with a repetition rate of 5 GHz. The obtained results show differences between BiBurst mode and conventional single pulse mode laser ablation, with a remarkable increase in ablation efficiency for the BiBurst mode, which under optimal conditions can ablate a volume 4.5 times larger than the single pulse mode ablation while delivering the same total energy in the process.
Spectrophotometric Determination of the Stabilities of Ethylenediamine tetraacetate Chelates (1953)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSpectrophotometric Determination of the Stabilities of Ethylenediamine tetraacetate ChelatesVincent L. Hughes and Arthur E. MartellCite this: J. Phys. Chem. 1953, 57, 7, 694–699Publication Date (Print):July 1, 1953Publication History Published online1 May 2002Published inissue 1 July 1953https://pubs.acs.org/doi/10.1021/j150508a022https://doi.org/10.1021/j150508a022research-articleACS PublicationsRequest reuse permissionsArticle Views126Altmetric-Citations19LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
An MDL approach to the climate segmentation problem (2010)

This paper proposes an information theory approach to estimate the number of changepoints and their locations in a climatic time series. A model is introduced that has an unknown number of changepoints and allows for series autocorrelations, periodic dynamics, and a mean shift at each changepoint time. An objective function gauging the number of changepoints and their locations, based on a minimum description length (MDL) information criterion, is derived. A genetic algorithm is then developed to optimize the objective function. The methods are applied in the analysis of a century of monthly temperatures from Tuscaloosa, Alabama.
The bromodomain protein GTE6 controls leaf development in <i>Arabidopsis</i> by histone acetylation at <i>ASYMMETRIC LEAVES1</i> (2005)

The transition from the juvenile to the mature phase during vegetative development in plants is characterized by changes in leaf shape. We show that GENERAL TRANSCRIPTION FACTOR GROUP E6 (GTE6) regulates differences in leaf patterning between juvenile and mature leaves in Arabidopsis. GTE6 encodes a novel small bromodomain-containing protein unique to plants. Mutations in GTE6 disrupt the formation of elliptical leaf laminae in mature leaves, whereas overexpression of GTE6 resulted in elongated juvenile leaves. GTE6 positively regulates the expression of ASYMMETRIC LEAVES1 (AS1), which encodes a myb-domain protein that controls proximodistal patterning of leaves. Using chromatin immunoprecipitation (ChIP) assays, we show that GTE6 is associated with the promoter and the start of the transcribed region of AS1 and up-regulates expression of AS1 through acetylation of histones H3 and H4. Genetic studies demonstrated that AS1 is epistatic to GTE6, indicating that GTE6 regulates AS1 during leaf morphogenesis. Chromatin remodeling at AS1 is a key regulatory mechanism in leaf development, which ensures the continual production of mature leaves following juvenile-adult transition, thereby maintaining the identity of the mature vegetative phase.
Aryl Sulfides and Sulfones Containing the Diethylaminoethyl Group (1945)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAryl Sulfides and Sulfones Containing the Diethylaminoethyl GroupB. Puetzer and A. R. SurreyCite this: J. Am. Chem. Soc. 1945, 67, 2, 343–344Publication Date (Print):February 1, 1945Publication History Published online1 May 2002Published inissue 1 February 1945https://pubs.acs.org/doi/10.1021/ja01218a507https://doi.org/10.1021/ja01218a507research-articleACS PublicationsRequest reuse permissionsArticle Views25Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Evaluation of tamoxifen as a therapy to augment alpha-1-antitrypsin concentrations in Z homozygous alpha-1-antitrypsin-deficient subjects. (1987)

Tamoxifen, an agent that binds to intracytoplasmic estrogen receptors, was evaluated as a possible means of increasing alpha-1-antitrypsin (alpha 1AT) synthesis and/or secretion and thus alpha 1AT serum levels in subjects with the homozygous form of alpha 1AT deficiency. Administration of tamoxifen (10 mg twice daily) to 30 Z homozygotes for a 30-day period was not associated with adverse reactions. However, although serum alpha 1AT levels increased significantly (p less than 0.03), the increase was minor (average pretreatment levels, 32 +/- 1 mg/dl; levels at 30 days of therapy, 35 +/- 1 mg/dl) and far below the "threshold" level of 80 mg/dl considered "protective" against an increased risk for emphysema. Thus, while the concept that increasing alpha 1AT synthesis and/or secretion is a rational goal for treating the Z homozygous form of alpha 1AT deficiency, tamoxifen will not be useful in this regard.
Paranasal Sinus Masses of Rocky Mountain Bighorn Sheep (<i>Ovis canadensis canadensis</i>) (2010)

This article describes 10 cases of paranasal sinus masses in Rocky Mountain bighorn sheep (Ovis canadensis canadensis). Among 21 bighorns that were examined from 11 herds in Colorado, 10 individuals (48%) from 4 herds (36%) had masses arising from the paranasal sinuses. Affected animals included 9 of 17 females (53%) and 1 of 4 males (25%), ranging in age from approximately 2 years to greater than 10 years. Defining gross features of these masses included unilateral or bilateral diffuse thickening of the respiratory lining of the maxillary and/or frontal sinuses, with abundant seromucinous exudate in the affected sinus cavities. Defining histologic features of these masses included chronic inflammation and proliferation of mesenchymal and epithelial cells of the mucosa and submucosa. Epithelial changes included hyperplasia of mucosal epithelium, hyperplasia of submucosal glands and ducts, and neoplasia (adenocarcinoma). Mesenchymal changes included submucosal myxedema, submucosal fibroplasia/fibrosis, bone destruction, and neoplasia (myxomatous fibroma). Specific immunohistochemistry and polymerase chain reaction for Jaagsiekte sheep retrovirus and enzootic nasal tumor virus were performed with negative results.
Sleeve Insertion and Collagen Coating Improve Nerve Regeneration Through Vein Conduits (1993)

Vein grafts have been used as conduits for nerve regeneration in both research protocols and clinical situations. Results to date are encouraging. This study investigated several variations in the vein graft model in an attempt to enhance peripheral nerve regeneration. Results showed that the jugular vein, with an improved suture technique made possible by its larger diameter, is superior to the femoral vein as a conduit for regeneration of the sciatic nerve in the rat. The larger diameter of the jugular vein and its lack of valves provided less hinderance to regenerating axons. Results also showed that coating the luminal epithelium of the jugular vein with type I collagen gel greatly improved regeneration.
Fetal responses to asphyxia (2003)

For most of the twentieth century the concept of perinatal brain damage centered around cerebral palsy and intrapartum asphyxia. It is only in the last 20 years that this view has been seriously challenged by clinical and epidemiological studies which have demonstrated that approximately 70–90% or more of cerebral palsy is unrelated to intrapartum events. Many term infants who subsequently develop cerebral palsy are believed to have sustained asphyxial events in midgestation. In some cases, prenatal injury may lead to chronically abnormal heart rate tracings, and impaired ability to adapt to labor which may be confounded with an acute event.
Fused InGaAs-Si avalanche photodiodes with low-noise performances (2002)

A fused InGaAs-Si avalanche photodiode (APD) with a low excess noise factor of 2.3 at a gain of 20 is reported. This corresponds to a k factor of 0.02 for the silicon avalanche region. Dark current density as low as 0.04 mA/cm/sup 2/ at -5 V and 0.6 mA/cm/sup 2/ at a gain of 10 are measured; a small thermal coefficient, 0.09%//spl deg/C, of the breakdown voltage is observed for this APD.
Carotid Plaque Echolucency Increases the Risk of Stroke in Carotid Stenting (2004)

Carotid plaque echolucency, as measured by GSM < or =25, increases the risk of stroke in CAS. The inclusion of echolucency measured as GSM in the planning of any endovascular procedure of carotid lesions allows stratification of patients at different risks of complications in CAS.
Detection of quiescent phases in echocardiography data using non-linear filtering and boundary detection (2012)

In order to detect the quasi-stationary states of the heart within a cardiac cycle from echocardiography data, we present an algorithm that uses non-linear filtering and boundary detection. The non-linear filtering algorithm involves anisotropic diffusion to remove the speckle noise from the data and to smoothen the homogeneous regions while preserving the edges. Following this, we perform binary thresholding and boundary detection, and observe the positional changes in the region of interest. From a series of echocardiography images, we derived the regions of cardiac quiescence, which we then plotted on the electrocardiograph (ECG) R-R interval. It is observed that the quiescence occurs in the diastolic region of the ECG signal, but the position and length of quiescence varies across multiple cardiac cycles for the same individual.
Nucleotide sequence of the Escherichia coli motB gene and site-limited incorporation of its product into the cytoplasmic membrane (1986)

The motB gene product of Escherichia coli is an integral membrane protein required for rotation of the flagellar motor. We have determined the nucleotide sequence of the motB region and find that it contains an open reading frame of 924 nucleotides which we ascribe to the motB gene. The predicted amino acid sequence of the gene product is 308 residues long and indicates an amphipathic protein with one major hydrophobic region, about 22 residues long, near the N terminus. There is no consensus signal sequence. We postulate that the protein has a short N-terminal region in the cytoplasm, an anchoring region in the membrane consisting of two spanning segments, and a large cytoplasmic C-terminal domain. By placing motB under control of the tryptophan operon promoter of Serratia marcescens, we have succeeded in overproducing the MotB protein. Under these conditions, the majority of MotB was found in the cytoplasm, indicating that the membrane has a limited capacity to incorporate the protein. We conclude that insertion of MotB into the membrane requires the presence of other more hydrophobic components, possibly including the MotA protein or other components of the flagellar motor. The results further reinforce the concept that the total flagellar motor consists of more than just the basal body.
Semisynthetic Analogues of an Enzymically Active Complex Formed between Two Overlapping Fragments of Staphylococcal Nuclease (1971)

Abstract It has been shown previously that a cyanogen bromide fragment of staphylococcal nuclease (149 residues) containing the COOH-terminal portion of the molecule (residues 99 to 149) can undergo noncovalent interaction with a product of limited trypsin digestion of nuclease (residues 1 to 126) to yield a complex with approximately 10% the enzymic activity of the native protein. The two interacting fragments, when alone in solution, appear to be essentially structureless while the active complex exhibits much of the ordered structure of nuclease itself. The studies reported here have investigated, in a qualitative manner, the minimum structural requirements of the (99-149) fragment for productive complementation. The single tryptophan residue of nuclease, at position 140, may be replaced with phenylalanine and the fragment may be shortened at the NH2 terminus to the region of residues 116 to 117 and at the COOH terminus to position 140 without elimination of capacity to support the formation of a complex with at least partial activity.
Low-frequency noise measurements on AlGaAs/GaAs resonant tunnel diodes (1989)

An experimental apparatus and procedure using noise measurement techniques in order to identify conduction mechanisms in resonant tunnel diodes (RTDs) due to defect-assisted tunneling is developed. The theory of noise measurements is discussed as the basis for the appropriate modeling of RTD noise data. Nonlinear and linear algorithms are developed to model these data and simulation test results are presented. Equipment target specifications are outlined and a functional equipment setup and procedure are also discussed. Sample results of a RTD noise measurement and of a determination of activation energy and capture cross section are presented.
Political Culture and Corruption Issues in State Politics: A New Measure of Corruption Issues and a Test of Relationships to Political Culture (2016)

To what extent does variation in political culture influence the number and types of corruption issues arising in U.S. states? Drawing upon Daniel Elazar’s enduring typology of American political subcultures and using a new news-based measure of corruption issues, we find that political culture remains a “sticky” deep determinant of the distribution of corruption issues across states. Unlike previous empirical studies we do not treat political culture as a set of consensus values, but rather emphasize tensions that can arise when multiple political cultures coexist in a state. Our findings are of interest not only with respect to the enduring role of culture itself, but also in terms of how it might help us understand the growing number of actions that are legal, yet still seen by many as corrupt.