gebhart/patrepeval huggingface dataset:
Triblock copolymer based thermoplastic elastomeric gels of a large service temperature range: preparation and characterization (1997)

Abstract Poly(methyl methacrylate)‐ block ‐polybutadiene‐ block ‐poly(methyl methacrylate) (MBM) triblock copolymers and their hydrogenated counterparts with poly(ethylene‐ co ‐1,2‐butylene) midblock (MEBM) were swollen by an aliphatic oil of high boiling point which is a selective solvent for the central block. Thermoreversible gels are accordingly formed by both MBM and MEBM copolymers above a critical polymer content ( Cr ), which depends on the nature of the midblock and not on the copolymer molecular weight, at least in the investigated range. Cr has been found to be 5 wt.‐% for an MBM block copolymer and 2 wt.‐% for MEBM copolymers of various molecular weights. Gels of MEBM triblock copolymers exhibit interesting mechanical properties, such as high elongation at break (up to 870%) and high tensile strength (32 kPa). The most interesting feature of the MEBM gels is an upper service temperature as high as 170°C, thus more than 100°C higher than the value (47°C) reported for gels of an SEBS copolymer (S = polystyrene) of comparable molecular weight (100000) and composition (ca. 30 wt.‐% hard block). The morphology of MEBM gels was studied by scanning electron microscopy (SEM) and found to be cocontinuous in case of a gel containing 20 wt.‐% copolymer.
deacetylation of the glucocorticoid receptor enables NF-κB suppression (2006)

Glucocorticoids are the most effective antiinfl ammatory agents for the treatment of chronic infl ammatory diseases even though some diseases, such as chronic obstructive pulmonary disease (COPD), are relatively glucocorticoid insensitive. However, the molecular mechanism of this glucocorticoid insensitivity remains uncertain. We show that a defect of glucocorticoid receptor (GR) deacetylation caused by impaired histone deacetylase (HDAC) 2 induces glucocorticoid insensitivity toward nuclear factor (NF)-�� B–mediated gene expression. Specifi c knockdown of HDAC2 by RNA interference resulted in reduced sensitivity to dexamethasone suppression of interleukin 1�� –induced granulocyte/macrophage colony-stimulating factor production. Loss of HDAC2 did not reduce GR nuclear translocation, GR binding to glucocorticoid response element (GRE) on DNA, or GR-induced DNA or gene induction but inhibited the association between GR and NF-�� B. GR becomes acetylated after ligand binding, and HDAC2-mediated GR deacetylation enables GR binding to the NF-�� B complex. Sitedirected mutagenesis of K494 and K495 reduced GR acetylation, and the ability to repress NF-�� B–dependent gene expression becomes insensitive to histone deacetylase inhibition. In conclusion, we show that overexpression of HDAC2 in glucocorticoid-insensitive alveolar macrophages from patients with COPD is able to restore glucocorticoid sensitivity. Thus, reduction of HDAC2 plays a critical role in glucocorticoid insensitivity in repressing NF-�� B– mediated, but not GRE-mediated, gene expression.
New therapeutic approach to heart failure due to myocardial infarction based on targeting growth hormone-releasing hormone receptor (2015)

Treatment with GHRH agonists appears to reduce the inflammatory responses post-MI and may consequently improve mechanisms of healing and cardiac remodeling by regulating pathways involved in fibrosis, apoptosis and cardiac repair. Patients with cardiac dysfunction could benefit from treatment with novel GHRH agonists.
Differential form of the collision integral for a relativistic plasma (1987)

A differential formulation for the Beliaev and Budker relativistic collision integral is presented. This permits the rapid numerical evaluation of the collision integral. The decomposition into spherical harmonics allows the collision operator to be expressed in terms of one-dimensional integrals for simple background distributions. This is useful in carrying out analytical work. It also provides a convenient method for calculating the boundary conditions for the potentials. 6 refs.
New method for determination of the parameters of a channel waveguide (1992)

A new method for the determination of the parameters of channel integrated optical waveguides is proposed. This method is based on measuring the spectral transmission of a system comprising the investigated waveguide and single-mode fiber waveguides, which are brought into contact with the channel waveguide. The results are reported of an investigation of two channel waveguides formed in glass by a variety of methods and characterized by different refractive index profiles. The proposed method is found to be suitable for determination of the parameters of the refractive index profile of the investigated channel waveguides.
Evolution and Survival of Quantum Entanglement (2009)

Abstract : Theoretical foundations for methods to preserve quantum entanglement are explored and explained. These engage modifications and extensions and improvements of Markovian and perturbative and near-resonant approximations.
On the Formation of the Aerosols of Dimethyl Phthalate (1967)

過飽和蒸気の凝縮によるエーロゾルの生成機構を研究するため,フタル酸ジメチル(DMP)を試料として実験を行ない,エーロゾルの重量濃度,粒径とその分布および粒子数濃度におよぼすエーロゾル発生器の温度(110°～150℃),キャリヤーガスの流速(1.0～5.0l/min)などの影響を検討してつぎの結果を得た。重量濃度は,(1)一定流速下では温度とともに指数関数的に増大し,(2)一定温度下ではある流速において極大値を示すが,(3)流速依存性は高温ほど大きい。また,粒径は,(1)温度とともに増大し,(2)流速が増大すると逆に滅少するが,粒子数濃度は流速とともに増加する。単分散性は150℃, 2.Ol/min の条件下でもっともよい。
ChemInform Abstract: Four New Microginins, Linear Peptides from the Cyanobacterium Microcystis aeruginosa. (1999)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Exploiting PUF Models for Error Free Response Generation (2017)

Physical unclonable functions (PUF) extract secrets from randomness inherent in manufacturing processes. PUFs are utilized for basic cryptographic tasks such as authentication and key generation, and more recently, to realize key exchange and bit commitment requiring a large number of error free responses from a strong PUF. We propose an approach to eliminate the need to implement expensive on-chip error correction logic implementation and the associated helper data storage to reconcile naturally noisy PUF responses. In particular, we exploit a statistical model of an Arbiter PUF (APUF) constructed under the nominal operating condition during the challenge response enrollment phase by a trusted party to judiciously select challenges that yield error-free responses even across a wide operating conditions, specifically, a $ \pm 20\% $ supply voltage variation and a $ 40^{\crc} $ temperature variation. We validate our approach using measurements from two APUF datasets. Experimental results indicate that large number of error-free responses can be generated on demand under worst-case when PUF response error rate is up to 16.68\%.
Dissection of the mechanisms of immune injury in rheumatoid arthritis, using total lymphoid irradiation (1988)

Eleven patients with intractable rheumatoid arthritis were treated with total lymphoid irradiation. After radiotherapy, there was a marked decrease in the number and function of peripheral blood helper/inducer (Leu-3+) T lymphocytes, in the spontaneous secretion of interleukin-1 by synovial biopsy specimens, and in the activity of the joint disease. In contrast, levels of IgM, IgA, and IgG rheumatoid factors and C3 concentrations in blood and synovial fluid samples did not change significantly after therapy with total lymphoid irradiation.
Call Pickup Examples in SIP (2007)

This document walks through various examples and flows for
implementing call operations in SIP telephony. It focuses on
distributing as much processing as possible in the user agents in
accordance with the philosophy of end-point controlled call-control
(EPCC). Various difficulties in implementing pickup are
discussed, and further suggestions and discussion are solicited.
Hysterectomy, menopause, and estrogen use preceding Parkinson's disease: An exploratory case‐control study (2001)

We studied the association of Parkinson's disease (PD) with type of menopause (natural or surgical), age at menopause, and postmenopausal estrogen replacement therapy using a case-control design. We used the medical records-linkage system of the Rochester Epidemiology Project to identify 72 women who developed PD in Olmsted County, MN, during the twenty years 1976-1995. Each incident case was matched by age (+/- 1 year) to a general population control subject. We collected exposure data through review of the complete medical records of cases and control subjects in the system. PD cases had undergone hysterectomy (with or without unilateral oophorectomy) significantly more often than control subjects (odds ratio [OR] = 3.36; 95% confidence interval [CI] = 1.05-10.77). In addition, PD cases had experienced early menopause (< or = 46 years) more commonly than control subjects (OR = 2.18; 95% CI = 0.88-5.39). Finally, PD cases had used estrogens orally or parenterally for at least 6 months after menopause less frequently (8%) than control subjects (14%; OR = 0.47; 95% CI = 0.12-1.85). However, the findings for early menopause and estrogen replacement therapy were not statistically significant. Despite the limited sample size of this exploratory study, we hypothesize that there is an increased risk of PD in conditions causing an early reduction in endogenous estrogen. This hypothesis needs to be confirmed in a larger study.
Telescope-Performance Reciprocity for Propagation in a Turbulent Medium (1972)

Get PDF Email Share Share with Facebook Tweet This Post on reddit Share with LinkedIn Add to CiteULike Add to Mendeley Add to BibSonomy Get Citation Copy Citation Text D. L. Fried and H. T. Yura, "Telescope-Performance Reciprocity for Propagation in a Turbulent Medium," J. Opt. Soc. Am. 62, 600-602 (1972) Export Citation BibTex Endnote (RIS) HTML Plain Text Citation alert Save article
The hexose specificity of hexokinase in brain from various species (1957)

Research Article| October 01 1957 The hexose specificity of hexokinase in brain from various species Margaret Kerly; Margaret Kerly 1Department of Biochemistry, University College London Search for other works by this author on: This Site PubMed Google Scholar D. H. Leaback D. H. Leaback 1Department of Biochemistry, University College London Search for other works by this author on: This Site PubMed Google Scholar Biochem J (1957) 67 (2): 250–252. https://doi.org/10.1042/bj0670250 Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn MailTo Cite Icon Cite Get Permissions Citation Margaret Kerly, D. H. Leaback; The hexose specificity of hexokinase in brain from various species. Biochem J 1 October 1957; 67 (2): 250–252. doi: https://doi.org/10.1042/bj0670250 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsBiochemical Journal Search Advanced Search This content is only available as a PDF. © 1957 CAMBRIDGE UNIVERSITY PRESS1957 Article PDF first page preview Close Modal You do not currently have access to this content.
Derivatization of biomass-derived 5-(hydroxymethyl)furfural through heterogeneous NHC oxidative catalysis. (2019)

The biomass-derived 5-(hydroxymethyl)furfural (HMF) represents a promising platform chemical owing to its sustainability and functional groups availability for further transformations.1\nIn the present work, we propose the application of the oxidative system composed by a heterogeneous triazolium pre-catalyst, iron(II) phthalocyanine and air for the selective conversion of 5-hydroxymethylfurfural (HMF) into the added-value 5-hydroxymethyl-2-furancarboxylic acid (HMFCA) and corresponding ester, thioester and amide derivatives.2 HMF reactivity was investigated via two different synthetic routes: a one-pot two-step process through a polyester oligomer intermediate (poly-HMF, Mw = 389-1258) and a direct coupling. Both strategies allow efficient access to 5-HMF derivatives with good yields and efficient catalyst recycle.
Substrate Temperature Measurement during Ion Implantation (1975)

A quantitative estimation of the substrate temperature rise in situ during ion implantation is performed using a wide range infrared thermometer. The accuracy of the measurement is within ±3°C. The ion implantation is carried out on a silica glass wafer and the temperature rise is measured for He+, B+, N+, N+2, P+ and BF+2 ion species. The higher the implant power is, the higher becomes the substrate temperature, and an implant power of 6 W/cm2 raises the substrate temperature to 730°C. The mass dependence of the temperature rise is observed, and is explained by the electrical and nuclear stopping power of the substrate.
Nuclear myxovirus-resistance protein Mx is a minor histocompatibility antigen. (1990)

Minor histocompatibility antigens (MiHAgs) cause slow-to-rapid organ transplant rejection by immunocompetent hosts and mild-to-severe graft-versus-host reactions in immunosuppressed hosts. MiHAgs are allelic forms of major histocompatibility complex (MHC) class I-restricted self-antigens recognized by cytotoxic T cells and usually are defined immunogenetically. Although structurally not identified as yet, it is assumed that MiHAgs are internal cell antigens that are processed and then presented by MHC class I proteins similar to viral antigens. To define a MiHAg both molecularly and functionally, we took advantage of the allelic difference of the structurally characterized intracellular myxovirus-resistance protein (Mx) and investigated its antigenicity. Skin grafts from congenic Mx+ mice carrying the functional Mx1 gene were rejected by mice lacking a functional Mx1 gene (Mx- mice). In parallel, cytotoxic MHC class I-restricted effector T cells specific for Mx protein and the H-2Kk antigen (but not for several other allelic H-2 antigens) were strongly induced in Mx- mice immunized with spleen cells from interferon-treated Mx+ mice. These data show that allelic forms of cell internal proteins presented by MHC class I may act as MiHAgs.
Micropatterning of proteins using dewetting (2006)

The ability to control protein and cell positioning on a microscopic scale is crucial in many biomedical and bioengineering applications, such as tissue engineering and development of biosensors. We propose here a novel micro-patterning technique that does not require templates, molds or stencils and is based on patterning polymer films bilayers by dewetting processes, followed by the selective adsorption of proteins from buffer solutions. Evidence is obtained by fluorescence microscopy and atomic force microscopy (AFM) that proteins adsorb preferentially on isolated bio-adhesive micro-patches in a protein-resistant background. The surface density of proteins inside the adhesive islands can be tailored by varying the concentration of the protein solutions employed. Furthermore, the method can also easily produce inverse patterns, containing non-fouling islands in a protein-adhesive matrix. The produced micropatterned substrates should prove useful to studies in biosensor and bioassay development and as substrates to study growth and motility in cell cultures.
Very fast methodology for the simulation of CMOS combinatorial circuits including noise (2008)

The noise immunity of digital CMOS designs is considered as one of the reasons for its huge success. However, low power design has become necessary to cope with the power demand and shrinking device sizes. At the same time, the electromagnetic compatibility requirements have become more and more stringent, with the result that Electromagnetic Interference (EMI) can be considered as a serious noise source for future digital designs. In this paper, the effects of EMI on digital combinational logic is discussed, and a model for the immunity of digital circuits is proposed.
Skull Base Surgery of the Temporal Bone (2010)

Objectives: The aim of this study was to review major temporal bone cases performed by one surgeon, and to highlight pitfalls and progress in the surgical management of previously "unresectable" neoplasms.
Relations entre grandeurs microscopiques et macroscopiques pour un solide avec changement de phase irréversible (1992)

On étudie la caractérisation du comportement global du matériau à partir de la connaissance des propriétés locales de ses composants élastiques ou élastoplastiques. On fait l'hypothèse que l'un des matériaux constitutifs peut se transformer en un second composant, de manière irréversible, ce changement de phase n'étant dû qu'à un critère exprimé sur les grandeurs mécaniques.
Effects of neoadjuvant trastuzumab, pertuzumab and palbociclib on Ki67 in HER2 and ER-positive breast cancer (2022)

The crosstalk between estrogen and HER2 receptors and cell-cycle regulation sustains resistance to endocrine therapy of HER2- and hormone receptor-positive breast cancer. We earlier reported that women with HER2 and ER-positive breast cancer receiving neoadjuvant dual HER2-block and palbociclib in the NA-PHER2 trial had Ki67 decrease and 27% pathological complete responses (pCR). We extended NA-PHER2 to Cohort B using dual HER2-block and palbociclib without fulvestrant and report here Ki67 drops at week-2 (mean change -25.7), at surgery (after 16 weeks, mean change -9.5), high objective response (88.5%) and pCR (19.2%). In Cohort C [Ki67 > 20% and HER2<sub>low</sub> (IHC 1+/2+ without gene amplification)], women also received fulvestrant, had dramatic Ki67 drop at week 2 (-29.5) persisting at surgery (-19.3), and objective responses in 78.3%. In view of the favorable tolerability and of the efficacy-predictive value of Ki67 drop at week-2, the chemotherapy-free approach of NA-PHER2 deserves further investigation in HER2 and ER-positive breast cancer. The trial is registered with ClinicalTrials.gov, number NCT02530424.
Coke Formation on Pt/ZrO<sub>2</sub>/Al<sub>2</sub>O<sub>3</sub> Catalysts during CH<sub>4</sub> Reforming with CO<sub>2</sub> (2002)

The CO2 reforming of methane was studied over Pt supported on Al2O3, ZrO2, and x % ZrO2/Al2O3 (1 ≤ x ≤ 20 wt %). The Pt/Al2O3 deactivated very quickly during 20 h onstream at 1073 K and a CH4/CO2 ratio of 1:1, while the catalysts with a ZrO2 content above 5 wt % presented improved stability during 60 h. Temperature-programmed oxidation studies showed that the amount of carbon on Pt/Al2O3 is much larger than that on zirconia-containing catalysts. Deactivation is attributed to carbon formation surrounding the metal−support perimeter. The high stability of zirconia-based catalysts is probably due to strong Pt−Zrn+ interactions, which reduce carbon formation during the reaction by promoting CO2 dissociation. High ratios of CH4/CO2 were also used in an attempt to accelerate deactivation, but even under these severe deactivation conditions, the catalyst with 10 wt % ZrO2 exhibited excellent stability.
ChemInform Abstract: Ring‐Expansion by a Wittig‐Prévost Sequence. (1986)

Abstract The tetralones (I) are converted to the methylene derivatives (II), which then react with silver nitrate, iodine, and methanol to produce the ring expansion products (III); (IV) and (V) are obtained as by‐products.
New Fluorination Reactions of Ammonium Bifluoride (1990)

This paper describes a novel route for the production of low‐oxygen‐containing fluorozirconate glasses. The process involves the use of a hitherto unknown solid‐state chemical reaction between ammonium bifluoride and specific anhydrous and hydrated metal fluoride salts. The products are defined as ammonium fluoride–metal fluoride complexes. The kinetics of their formation and subsequent dissociation were followed by thermogravimetric analysis. It was observed that these complexes decompose with the evolution of HF above temperatures at which ammonium bifluoride decomposes and where its supply may be exhausted. These materials have been used to melt fluorozirconate glasses. The oxygen contents of these glasses have been dramatically reduced to approximately 10 ppm. The glass stability, as defined by the lack of devitrification on reheating, also appears to increase with a lowering of the oxygen content. This implies that the mechanism of nucleation and growth is predominantly heterogeneous and not homogeneous nucleation. Furthermore, the production of long lengths of crystal‐free fluoride fibers for transcontinental optical communication systems appears to be a realistic goal, especially if the heterogeneities can be eliminated.
Immunohistochemical Analysis of the Microanatomy of Primate Ovary (1996)

The ovary is a complex organ composed of cells of diverse lineages. Therefore, in this study we examined whether immunolocalization of various cytoskeletal, epithelial, immune-cell, and neural-associated proteins can differentiate various cells in the baboon and human ovaries. Surface epithelial cells exhibited immunoreactivity for cytokeratin and desmin, however, they did not immunostain for other epithelial markers such as carcinoembryonic antigen or epithelial membrane antigen. Smooth muscle actin was distributed apically whereas vimentin was localized basally in these cells. Ova exhibited strong immunoreactivity for S-100, Leu-M1, and neurofilament and did not show immunoreactivity for epithelial and cytoskeletal proteins. In antral follicles and theca cells, and after formation of corpus luteum, both granulosa and theca cells expressed immunoreactivity for vimentin. Cytokeratins were absent in the preantral and antral follicles. However, atresia and development of apoptosis was associated with expression of immunoreactive cytokeratins in atretic follicles. Development of corpus luteum led to major changes in the immunophenotype of follicular cells. The mere presence of immunoreactivity for cytokeratin and a strong immunoreactivity for desmin in the luteinized granulosa and not in the theca cells allowed discrimination of these cells from each other and from their ancestral cells. Proliferating cell nuclear antigen was present in various ovarian cells except for ovum. The distinct patterns of expression of cytoskeletal, epithelial, and neural-associated proteins in various cells of the ovary facilitates their identification and discrimination.
Effect of turpentine treatment on hemorheological parameters in rats (1991)

The effect of subcutaneous treatment of turpentine on hemorheological parameters was studied ex vivo in rats. A dose-response study (0.2 to 5 ml/kg) was performed on a series of parameters: whole blood apparent viscosity, plasma viscosity, plasma fibrinogen content, total plasma protein, hematocrit, erythrocyte aggregation and filterability. Significant alterations of all hemorheological parameters were observed 24 hrs after the turpentine treatment except for erythrocyte filterability and hematocrit values. In most cases, these alterations were significant (p<0.01) for doses higher than 0.3 ml/kg, with a maximum effect usually observed for a dose ≥ 1 ml/kg. These hemorheological alterations were still present 48 hrs after turpentine treatment and in the same order of magnitude. Thus, the present study demonstrated for the first time that turpentine treatment induced significant alterations of hemorheological parameters in dose-dependent manner, probably via an increase in plasma protein components.