gebhart/patrepeval huggingface dataset:
Fluorescence turn-on detection of Sn<sup>2+</sup> in live eukaryotic and prokaryotic cells (2014)

Sn(2+) is usually added to toothpaste to prevent dental plaque and oral disease. However, studies of its physiological role and bacteriostatic mechanism are restricted by the lack of versatile Sn(2+) detection methods applicable to live cells, including Streptococcus mutans. Here we report two Sn(2+) fluorescent probes containing a rhodamine B derivative as a fluorophore, linked via the amide moiety to N,N-bis(2-hydroxyethyl)ethylenediamine (R1) and tert-butyl carbazate group (R2), respectively. These probes can selectively chelate Sn(2+) and show marked fluorescence enhancement due to the ring open reaction of rhodamine induced by Sn(2+) chelation. The probes have high sensitivity and selectivity for Sn(2+) in the presence of various relevant metal ions. Particularly, both R1 and R2 can target lysosomes, and R2 can probe Sn concentrations in lysosomes with rather acidic microenvironment. Furthermore, these two probes have low toxicity and can be used as imaging probes for monitoring Sn(2+) not only in live KB cells (eukaryotic) but also in Streptococcus mutans cells (prokaryotic), which is a useful tool to study the physiological function of Sn(2+) in biological systems.
Research of AODV routing protocol based on link availability prediction (2008)

The AODV routing protocol could not adapt to high dynamic topology change well. According to extend the AODV routing algorithm by the link availability prediction, the nodes selected the most stable path to route based on the power of received packets and the link continuous availability time, and started the route maintenance in advance before the link broken. The simulation results demonstrate that the improved AODV routing protocol increased the packet deliv- ery ratio and decreases the average end-to-end delay, and the reliability of the routing protocol is strengthened.
Descendent clipping and filtering for cubic metric reduction in OFDM systems (2013)

The cubic metric (CM) is being regarded as a more accurate metric for envelope fluctuations of orthogonal frequency division multiplexing (OFDM) signals than peak‐to‐average power ratio (PAPR). Iterative clipping and filtering (ICF) is a simple and efficient technique for PAPR reduction. However, analysis shows that it cannot achieve sufficient CM reduction due to the difference between the two metrics. Proposed is a new technique called descendent clipping and filtering (DCF) for CM reduction. Unlike ICF, DCF introduces a new parameter termed descent factor to improve its performance. Simulation results show that DCF can achieve better performance with only one iteration than ICF with multiple iterations
Piloted simulation of NextGen time-based taxi clearances and tailored departures (2009)

This paper describes the results of a medium-fidelity piloted flight deck simulation of future surface operations. Sixteen commercial transport pilots conducted time-based taxi-out operations at DFW airport under two next generation airspace (NextGen) implementations. In the limited NextGen implementation, time-based operations were defined by providing a taxi clearance with a commanded average speed to the pilot. In the advanced NextGen implementation, advanced avionics allowed for time-based taxi operations to be conducted with speed error-nulling algorithms and arrival time information. Results indicated that the Advanced NextGen implementation substantially improved pilots' ability to arrive at airport traffic flow points at the required time. An additional ldquotailored departurerdquo (i.e., NextGen 4-D departure) clearance verification task assessed the impact of time-based taxi on the departure phase of flight. Results indicated that time-based taxi operations in general, and specifically the advanced NextGen implementation, might add to pilot workload during taxi out. Future research regarding the assessment and the impact of time-based taxi operations is required.
FURTHER STUDIES ON THE NEUROGENIC CONTROL OF THE ESTROUS CYCLE BY UTERINE DISTENTION<sup>1</sup> (1955)

THE mechanism by which the corpus luteum is caused to persist following fertilization in mammals which ovulate spontaneously during each reproductive cycle and which do not show pseudopregnancy following cervical stimulation is not known. The effects of uterine distention and the apparent importance of the uterine afferent nerve supply on the regulation of the estrous cycle of the ewe have been observed by Moore and Nalbandov (1953). They have shown that a foreign body introduced into the sheep uterus during the early luteal phase of the estrous cycle causes a marked decrease in the mean length of the estrous cycle. This phenomenon is dependent upon the nerve supply to the distended area of the uterine horn. Similarly Huston and Nalbandov (1953) and van Tienhoven (1953) have shown that oviducal stimulation may alter the qualitative and quantitative gondadotrophin secretion in the chicken.
Organisation of Indoor Navigation data from a data query perspective (2010)

Indoor Navigation is becoming a more and more important topic. It is a key tool for the integration of disabled people into environments which they are not familiar with. With this paper we want to address the problem of indoor navigation being much more complex than outdoor navigation with a thorough modelling of queries which a indoor navigation GIS database shall be able to answer quickly and present an organisation of indoor navigation data tailored to scalable and flexible indoor navigation.
Enhancing antibody folding and secretion by tailoring the Saccharomyces cerevisiae endoplasmic reticulum (2016)

Engineering protein folding in vivo is a major task for biopharmaceuticals production in yeast and needs to be optimized at several levels. By rational strain design and high-throughput screening applications we were able to increase the specific secreted antibody yields of S. cerevisiae up to 10-fold, providing a promising strain for further process optimization and platform development for antibody production.
Fabrication and SERS Performances of Metal/Si and Metal/ZnO Nanosensors: A Review (2019)

Surface-enhanced Raman scattering (SERS) sensors are very powerful analytical tools for the highly sensitive detection of chemical and biological molecules. Substantial efforts have been devoted to the design of a great number of hybrid SERS substrates such as silicon or zinc oxide nanosystems coated with gold/silver nanoparticles. By comparison with the SERS sensors based on Au and Ag nanoparticles/nanostructures, higher enhancement factors and excellent reproducibilities are achieved with hybrid SERS nanosensors. This enhancement can be due to the appearance of hotspots located at the interface between the metal (Au/Ag) and the semiconducting substrates. Thus, in this last decade, great advances in the domain of hybrid SERS nanosensors have occurred. In this short review, the recent advances of these hybrid metal-coated semiconducting nanostructures as SERS sensors of chemical and biological molecules are presented.
Acidic fibroblast growth factor gene 5′ non‐coding exon and flanking region from hamster DDT1 cells: Identification of the promoter region and transcriptional regulation by testosterone and aFGF protein (1993)

Abstract Selected clones of Syrian hamster DDT1‐MF2 cells are responsive to testosterone for growth. Heparin binding growth factor 1 (HBGF‐1) or acidic fibroblast growth factor (aFGF) can replace testosterone (T) in the stimulation of growth in these cells. This phenomena is correlated with testosterone's ability to elevate aFGF mRNA two‐ to threefold in DDT1 cells. To better understand the possible mechanisms of regulation of aFGF mRNA by steroids and other growth factors, we isolated the aFGF 5′ non‐coding exon and its flanking region from a EMBL3 DDT1 genomic library, using a 5′ non‐coding exon 69 bp DDT1 aFGF cDNA probe. Clones spanning 30 kb of genomic DNA were isolated. After restriction mapping and DNA sequence analysis, the clones were shown to contain all of the 5′ non‐coding exon included in the cDNA and approximately 10 kb of 5′ flanking region. RNase protection and primer extension assays confirmed that the 5′ non‐coding exon is included in the DDT1 aFGF mRNA and that a major transcription start site is approximately 136 bp upstream of the 5′ non‐coding splice junction of this exon. The 5′ flanking region DNA was inserted into pBLCAT3 reporter gene and transfected into DDT1 cells. Chloramphenicol acetyltransferase (CAT) assays demonstrated that there are promoter elements in the −1645/−392 and −392/+131 regions of the aFGF gene in the context of DDT1 cells. NIH 3T3 cells, on the other hand, show no CAT activity with these aFGF‐CAT plasmids. CAT assays also demonstrated that addition of testosterone (T) or aFGF to DDT1 cells increased CAT activity threefold. This activity was mapped to −1645 to −4 bp region of this DDT1 aFGF gene promoter. © 1993 Wiley‐Liss, Inc.
The cDNA and protein sequences of human lactate dehydrogenase B (1987)

Human lactate dehydrogenase B (LDH-B) cDNA was isolated and sequenced. The LDH-B cDNA insert consists of the protein-coding sequence (999 bp), the 5' (54 bp) and 3' (203 bp) non-coding regions, and the poly(A) tail (50 bp). The predicted sequence of 333 amino acid residues was confirmed by amino acid composition and/or sequence analyses of a total of 185 (56%) residues from tryptic peptides of human LDH-B protein. The nucleotide and amino acid sequences of the human LDH-B coding region show 68% and 75% homologies respectively with those of the human LDH-A. The peptide map and amino acid composition data have been deposited as Supplementary Publication SUP 50139 (7 pages) at the British Library Lending Division, Boston Spa, Wetherby, West Yorkshire LS23 7BQ, U.K., from whom copies are available on prepayment [see Biochem. J. (1987) 241, 5].
Nucleophilic-Substitution Reactions in Benzo[C][1,8]Naphthyridines (1986)

The reactions of 1-chloro-3-methyl-6-(p- methylphenoxy ) benzo [c][1,8] naphthyridine with a variety of nucleophiles are reported. The relative reactivity of the 1- and 6-positions depends on the nucleophile and reaction conditions. Anilines, and alkyl and aryl thioxides react at position 1, alkylamines and alkoxide at position 6, and acidified alcohol at both 1 and 6. Some possible reasons for these positional reactivities are discussed.
Environment-friendly Trivalent Chromate Treatment for Zn Electroplating (2006)

Hexavalent chromium passivation, as very effective anti-corrosion method, can not be used in the field of surface treatment for metal, any more. Throughout the world, this regulations which was applied to automotive industries will be extended to all industries including electronics industries in the near future. Therefore a new anti-corrosion method should be estab- lished without delay, and trivalent chromium passivation as an alternatives replace the hexavalent chromium passivation for the time being. This paper gives an overview of the currently available trivalent chromium passivation processes, and then it attempts to give an insight to develop a more effective trivalent chromium conversion coating process for possible sub- stitution of the hexavalent chromium passivation process.
The use of magnetostrictive film transducers in the measurement of elastic moduli and ultrasonic attenuation of solids (1992)

The authors describe a novel method and apparatus for measuring the elastic moduli and ultrasonic attenuation of small samples (millimeter dimensions) over a wide temperature range. In the most general case, a nonmagnetic sample is coated with a thin film of a magnetostrictive material (e.g., nickel or iron-cobalt alloy). This film performs both as a driving transducer and as a receiving transducer. An alternating magnetic field of variable frequency generates a periodic stress in the film and drives the sample into mechanical resonances. The permeability of the film changes when the sample is resonating and allows the detection of the resonances. The operation of the system and the mathematical procedures to deduce the elastic moduli and ultrasonic attenuation from the measured resonance spectra are exemplified with measurements on amorphous Ni80P20 in the temperature range of 80–520 K.
Electronics in the driving seat (1978)

Have you ever dreamed of owning a wonder car, with touch buttons for everything, including the gear shift? Well £32 620 will buy you the Aston Martin Lagonda, which boasts two microprocessors and a total of about 48 touch buttons for you to play with while you are stuck in a London traffic jam
Synthesis of Novel Acetylenic Cyclophanes with Helical Chirality:  Potential New Structures for Liquid Crystals (2000)

The synthesis of a series of novel acetylenic cyclophanes is described. X-ray crystallographic analysis of the core structure revealed a twisted conformation with helical chirality. Preliminary results suggest that these cyclophanes, with appropriate functionality, have the potential to act as unique liquid crystalline materials.
Synthesis of cationic styrene-acrylic acid ester copolymer emulsion for paper sizing (2016)

Surface sizing is an effective way to increase paper's water-resistance and printability. The purpose of this study was to study synthesis process to develop an efficient cationic styrene-acrylic acid ester emulsion (SAE) for the surface sizing of paper. Dimethylaminoethyl methacrylate methyl chloride (DMC) was used as the cationic monomer, and cationic starch or native starch was used as the emulsion stabilizer to copolymerize with styrene and butyl acrylate. The results indicated that the SAE synthesized with cationic starch and DMC had a high cationic charge density and a high DMC conversion rate. Paper sized with the cationic SAE had higher surface strength and lower Cobb value than the paper sized with other surface sizing agents such as, anionic SAE, and cationic or oxidized starch. Scanning electron micrographs revealed that the paper sized with a combination of oxidized starch and cationic SAE had smoother surface morphology when compared to the paper sized with oxidized starch alone, or with oxidized starch and anionic SAE.
ORGANIC PHOTOVOLTAIC CELLS: HISTORY, PRINCIPLE AND TECHNIQUES (2008)

In this review we present an overview of the different solar cells families. After recalling shortly the specificities of materials, the band structure, the electronic properties and the charge separation process in materials are shortly described. Then the new solar cell concepts are presented. Plastic solar cells consist either of two layers or a homogeneous mixture of two materials. One of them - either an dye or a semiconducting polymer - donates the electrons. The other component serves as the electron acceptor. Principies of these multi-layers and bulk heterojunctions are presented and discussed. Then some typical examples are presented, showing the fast evolution of the cells performances. Finally, a specific attention is devoted to the interfaces electrodes/organics. Indeed recent results show that, at least in the case of multi-layers cells, the introduction of thin buffer layers at the interfaces cathode/organic acceptor and/or anode/organic donor, can strongly improve the efficiency of the solar cells. About the interface acceptor/cathode, we report the influence of an exciton-blocking layer and/or an A1203 thin layer on the efficiency of CuPc/C60 based photovoltaic cells. The presence, or not, of a thin A1203 layer depends on the encapsulating process of the devices. In the case of glass/ITO/CuPc/C60/Al cells, the presence of an A1203 thin layer at the interface organic acceptor/aluminium increases strongly the open circuit voltage of the cells but decreases slightly their short circuit current and fill factor. In the case of glass/ITO/CuPc/C60/Alq3/Al cells, the open circuit voltage is systematically higher than without Alq3. However, in that case, the presence of A1203 does not improve significantly the cell performances. All these results are discussed in terms of series and shunt resistance values related to possible oxygen contamination and covalent action with the Al films. The effectiveness of these different phenomena depends on the presence, or not, of Alq3 and/or A1203 layers. About the interface anode/organic donor, it is shown that an ultra thin metallic film improves significantly the short circuit current and the cell performances. The anode in plastic solar cells, which is a transparent conductive oxide (TCO), is usually an indium tin oxide film (ITO). Indeed, when a ZnO anode is used, cells performances are far from those achieved with ITO. However, strong improvement of the cells efficiency is encountered when an ultra thin buffer layer is introduced between the ZnO and the film. The presence of this ultra thin buffer layer at the surface of the TCO allows decreasing the performance difference between the cells using ITO and those using ZnO. More generally such ultra thin buffer layer improves the solar cells performances
Omega‐3 Fatty Acids and PPAR<i>γ</i> in Cancer (2008)

Omega-3 (or n-3) polyunsaturated fatty acids (PUFAs) and their metabolites are natural ligands for peroxisome proliferator receptor activator (PPAR)gamma and, due to the effects of PPARgamma on cell proliferation, survival, and differentiation, are potential anticancer agents. Dietary intake of omega-3 PUFAs has been associated with a reduced risk of certain cancers in human populations and in animal models. In vitro studies have shown that omega-3 PUFAs inhibit cell proliferation and induce apoptosis in cancer cells through various pathways but one of which involves PPARgamma activation. The differential activation of PPARgamma and PPARgamma-regulated genes by specific dietary fatty acids may be central to their distinct roles in cancer. This review summarizes studies relating PUFAs to PPARgamma and cancer and offers a new paradigm relating an n-3 PUFA through PPARgamma to the expression of the cell surface proteoglycan, syndecan-1, and to the death of cancer cells.
Identification and quantification of pyridoxine .beta.-glucoside as a major form of vitamin B6 in plant-derived foods (1987)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTIdentification and quantification of pyridoxine .beta.-glucoside as a major form of vitamin B6 in plant-derived foodsJesse F. Gregory III and Steven L. InkCite this: J. Agric. Food Chem. 1987, 35, 1, 76–82Publication Date (Print):January 1, 1987Publication History Published online1 May 2002Published inissue 1 January 1987https://pubs.acs.org/doi/10.1021/jf00073a018https://doi.org/10.1021/jf00073a018research-articleACS PublicationsRequest reuse permissionsArticle Views294Altmetric-Citations77LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
VMBooter (2014)

Infrastructure as a Service (IaaS) Cloud is emerging as a popular utility computing model in which computational resources like processor, memory, storage etc. are provided on demand. Virtual Machines (VMs) are used to provide on demand virtualized resources. Several VMs may run parallely on a physical machine depending on the demand. VM placement and VM resource allocation are two important problems in an infrastructure cloud. In such systems, performance interference may become a mutual problem between a VM which is booting and a VM which is coexisting, thus affecting the boot-time of a VM as well as response time of the coexisting VMs. The work presented here studies the impact of computational resources available on boot-time of a VM. Our experiments suggest to add a special server known as VMBooter inside an infrastructure cloud. Experimental results have shown considerable improvement in VM boot-time with lowering down the impact of performance interference on coexisting VMs with the help of VM migration.
Effect of surfactants on the antibacterial activity of preservatives. (1991)

Antibacterial activities of methyl-p-hydroxybenzoate, phenoxyethanol and chlorocresol against Pseudomonas aeruginosa were evaluated in the presence of varying concentrations of Tween 80. Below cmc level, the bactericidal activities increased with decrease in the surface tension values of Tween 80 solutions and with interfacial tension values of Tween 80 solution/liquid paraffin systems. Linear relationships were found to exist between the concentrations of each preservative required to reduce the microbial population by a factor 10(3) within 48 hours and the values of surface tension and interfacial tension respectively. Reduction in surface tension and interfacial tension would have increased the adsorption and uptake of preservatives by bacterial cells thereby killing the cells at a faster rate. Concentrations of Tween 80 above cmc also enhanced the antibacterial activities of these preservatives. This was attributed to the increase in the permeability of bacterial membranes to preservatives.
Brain Aging and Midlife Tofu Consumption (2000)

In this population, higher midlife tofu consumption was independently associated with indicators of cognitive impairment and brain atrophy in late life.
Effects of aliasing on numerical integration. (2005)

During the course of processing acceleration data from mechanical systems it is often desirable to integrate the data to obtain velocity or displacement waveforms. However, those who have attempted these operations may be painfully aware that the integrated records often yield unrealistic residual values. This is true whether the data has been obtained experimentally or through numerical simulation such as Runge-Kutta integration or the explicit finite element method. In the case of experimentally obtained data, the integration errors are usually blamed on accelerometer zero shift or amplifier saturation. In the case of simulation data, incorrect integrations are often incorrectly blamed on the integration algorithm itself. This work demonstrates that seemingly small aliased content can cause appreciable errors in the integrated waveforms and explores the unavoidable source of aliasing in both experiment and simulation-the sampling operation. Numerical analysts are often puzzled as to why the integrated acceleration from their simulation does not match the displacement output from the same simulation. This work shows that these strange results can be caused by aliasing induced by interpolation of the model output during sampling regularization.
State Monitor for Lithium-ion Power Battery Pack (2010)

Management technology for the lithium-ion traction batteries is the key research point for electric vehicles (EV). The states of temperature, current, single voltage, state of charge (SOC) and state of energy (SOE) should be acquired and evaluated timely. This paper has designed a battery state monitor system for the EV batteries based on LabView. Combined with the Extended Kalman Filter (EKF) of the optimal estimation theory and system parameter identify method, evaluate the SOC and SOE for lithium-ion batteries. The experiment results indicate that the EKF method is suitable for estimating the states of batteries, the virtual instrument technology could provide multiple message of the batteries.