gebhart/patrepeval huggingface dataset:
An experimental investigation on Lagrangian correlations of small-scale turbulence at low Reynolds number (2007)

Lagrangian auto- and cross-correlation functions of the rate of strain s 2 , enstrophy ω 2 , their respective production terms − s ij s jk s ki and ω i ω j s ij , and material derivatives, D s 2 /D t and Dω 2 /D t are estimated using experimental results obtained through three-dimensional particle tracking velocimetry (three-dimensional-PTV) in homogeneous turbulence at Re λ =50. The autocorrelation functions are used to estimate the Lagrangian time scales of different quantities, while the cross-correlation functions are used to clarify some aspects of the interaction mechanisms between vorticity ω and the rate of strain tensor s ij , that are responsible for the statistically stationary, in the Eulerian sense, levels of enstrophy and rate of strain in homogeneous turbulent flow. Results show that at the Reynolds number of the experiment these quantities exhibit different time scales, varying from the relatively long time scale of ω 2 to the relatively shorter time scales of s 2 , ω i ω j s ij and − s ij s jk s ki . Cross-correlation functions suggest that the dynamics of enstrophy and strain, in this flow, is driven by a set of different-time-scale processes that depend on the local magnitudes of s 2 and ω 2 . In particular, there are indications that, in a statistical sense, (i) strain production anticipates enstrophy production in low-strain–low-enstrophy regions (ii) strain production and enstrophy production display high correlation in high-strain–high-enstrophy regions, (iii) vorticity dampening in high-enstrophy regions is associated with weak correlations between − s ij s jk s ki and s 2 and between − s ij s jk s ki and D s 2 /D t , in addition to a marked anti-correlation between ω i ω j s ij and D s 2 /D t . Vorticity dampening in high-enstrophy regions is thus related to the decay of s 2 and its production term, − s ij s jk s ki .
Serum Prolactin Levels in Lactating Rats after Suckling or Exposure to Ether (1972)

Prolactin was measured by radioimmunoassay (RIA) in blood samples withdrawn through chronic intracardiac cannulas from undisturbed lactating mother rats after isolation from their pups for 6.5–12hr. Each mother was then caged with 6 of her pups for suckling or placed in an ether jar for 6 min. Additional blood samples for RIA were withdrawn at various times during and after suckling or treatment with ether. Plasma prolactin levels remained very low in mothers caring for their pups unless suckling occurred. With the onset of suckling, the plasma prolactin levels rose rapidly after a latency of 4 min to values elevated 14–fold within IS min. On the other hand, ether “stress” caused a 2–fold increase beginning 1–2 min after exposure and reaching its maximum by 4 min. The results suggest that suckling and ether “stress” trigger the release of prolactin by different mechanisms. (Endocrinology 91: 49, 1972)
Polarimetric SAR Interferometry with a Passive Polarimetric Micro-Satellite Concept (2002)

This paper proposes a spaceborne SAR mission consisting of a bi-static SAR configuration for estimation of the global vegetation biomass. The bi-static SAR configuration is based on a master satellite (transmitter) and on two or more receiver-only SAR satellites. The master satellite consists of an existing or planed SAR satellite (preferably in L-Band) with dual or full polarimetric capabilities. The receiver-only satellites have a dual polarized antenna and are positioned behind or ahead the master satellite, allowing single-pass fully polarimetric SAR interferometry. This innovative technique is used for reliable estimation of vegetation height on a global basis, which is offering a main input for the estimation of the global terrestrial biomass. The expected accuracy of the biomass estimation is compatible with the requirements posed by the Kyoto Protocol for the monitoring of carbon sinks as well as for ecological process modeling, forest inventory, and predictive modeling in hydrology.
Abstract 11237: Expression of Mitochondrial, Contractile, and Calcium Regulatory Proteins is Altered in Patients with Atrial Fibrillation (2021)

Introduction: Atrial fibrillation (AF) increases energy demand for contractile and electrical activity. Changes in left atrial (LA) protein expression of AF patients are poorly characterized. Hypothesis: Mitochondrial protein expression in patients with AF is altered in an attempt to meet increased energy demand. Methods: LA appendage tissue was obtained from 198 patients undergoing Maze surgery. At the time of surgery, 80 were in sinus rhythm (SR) (50 paroxysmal AF, 30 persistent AF) and 118 in AF (65 persistent AF, 53 permanent AF). Protein content was assessed by mass spectrometry and 2539 proteins were identified. Results: In AF compared to SR, 257 proteins were differentially expressed (q<0.05); 44 of 62 mitochondrial proteins detected (MitoCarta 3.0) were increased. KEGG pathway analysis revealed Oxidative Phosphorylation was increased (p=1.01E-3) in AF, including 17 subunits of the electron transport chain (A). The Hypertrophic Cardiomyopathy pathway was decreased (p=1.01E-03). Expression of ryanodine receptor, and troponin and tropomyosin subunits decreased, but tropomyosin 4 and myosin heavy chain 9 and 10 increased (B), providing evidence of changes in myofibrillar and calcium regulatory proteins in AF. Among 39 putative AF risk genes detectable at the protein level, 8 were altered in AF (C). The Tricarboxylic Acid Cycle KEGG pathway was decreased (p=2.55E-3) in patients with permanent compared to persistent AF, with no significant changes in other cellular pathways or protein expression of putative AF risk genes. Conclusions: In one of the largest proteomic datasets in human LA to date, we find that expression of proteins in metabolic, myofibrillar, and calcium regulation pathways is altered in patients with AF. Additional metabolic changes were detected with progression to permanent AF. These data identify proteins that are altered in patients with AF providing insight into cellular pathways that may be targeted for AF prevention and therapy.
Microtubule-associated protein tau as a therapeutic target in Alzheimer's disease (2014)

In our opinion, inhibition of abnormal hyperphosphorylation of tau is the most rational therapeutic target. Therapeutic approaches include restoration of the activity of protein phosphatase-2A, which is the major regulator of tau phosphorylation and the activity of which is compromised in AD brain, inhibition of one or more tau protein kinases which include GSK-3β, cyclin-dependent protein kinase-5, dual-specificity tyrosine phosphorylated-regulated kinase 1A, Ca(2+)/calmodulin-activated protein kinase II and casein kinase I, enhancement of O-GlcNAcylation of tau, and tau immunization.
Sobre la nutrición del Eucaliptus Globulus en el suroeste de España (1968)

19 paginas, 7 figuras, 5 tablas, 8 referencias.-- La publicacion se encuentra en la Seccion IV: Otros cultivos.-- El II Coloquio Europeo y Mediterraneo se celebro en Sevilla.
Prime–boost immunization with poxvirus or adenovirus vectors as a strategy to develop a protective vaccine for HIV-1 (2010)

Challenges in the development of an effective HIV-1 vaccine are myriad with significant hurdles posed by viral diversity, the lack of a human correlate of protection and difficulty in creating immunogens capable of eliciting broadly neutralizing antibodies. The implicit requirement for novel approaches to these problems has resulted in vaccine candidates designed to elicit cellular and/or humoral immune responses, to include recombinant DNA, viral and bacterial vectors, and subunit proteins. Here, we review data from clinical studies primarily of poxvirus and adenovirus vector vaccines, used in a heterologous prime-boost combination strategy. Currently, this strategy appears to hold the most promise for an effective vaccine based on results from immunogenicity testing and nonhuman primate challenge models, as well as the modest efficacy recently observed in the Thai prime-boost trial.
On characterizing and learning some classes of read-once functions (1989)

This thesis examines some classes of read-once functions. A read-once function is a boolean function that can be expressed as a read-once formula. A read-once formula is a boolean formula over the basis (AND, OR, NOT) in which each variable occurs exactly once. The thesis has two main parts.
In the first part, we introduce a generalization of the read-once property. We say that a function f is read-once on a subset Z of its inputs if f can be written as a formula in which every variable in Z occurs at most once. We present a simple necessary and sufficient condition for f to be read-once on Z. It has been shown that a monotone function f is read-once (on all its inputs) if and only if for every minterm S and for every maxterm T of f, $\vert S\bigcap T\vert=1$. We consider the natural generalization of this condition to the case of functions that are read-once on Z: for every minterm S and for every maxterm T of f, $\vert S\bigcap T\bigcap Z\vert\leq1$. We show that this generalized condition is necessary but not sufficient. We then present a class of functions of which the generalized condition is both necessary and sufficient.
The second part of the thesis addresses problems in computational learning theory. We present a polynomial time algorithm for exactly learning monotone read-once formulas with membership queries. Using this algorithm as a subroutine, we show a polynomial time algorithm for exactly learning unrestricted read-once formulas with membership and equivalence queries. Unrestricted read-once formulas cannot be learned with membership or equivalence queries alone, so this algorithm uses a minimal set of query types. We generalize the algorithm to show that other classes of unate formulas, such as the class of unate DNF formulas, can also be exactly learned in polynomial time using membership and equivalence queries.
Finally, we present results on the complexity of search and decision problems involving read-once functions.
ChemInform Abstract: Efficient Synthesis of New Benzocyclobutenic Phenethylamines, e.g. (IV) , (VI). (1993)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
SIGecom job market candidate profiles 2017 (2016)

This is the second annual collection of profiles of the junior faculty job market candidates of the SIGecom community. The twenty four candidates for 2017 are listed alphabetically and indexed by research areas that define the interests of the community. The candidates can be contacted individually or via the moderated mailing list ecom-candidates2017@acm.org.
Impact of pore topology and crystal thickness of nanosponge zeolites on the hydroconversion of ethylbenzene (2016)

Gas-phase hydroconversion of ethylbenzene was investigated using *MRE, MFI and MTW-type zeolite nanosponges with a hydrogenating component (Pt/Al<sub>2</sub>O<sub>3</sub>). Spacious channel interconnections in MFI was concluded to remarkably impact product selectivity compared to *MRE and MTW.
Electrically detected electron nuclear double resonance in 4H-SiC bipolar junction transistors (2019)

We demonstrate high signal-to-noise electrically detected electron-nuclear double resonance measurements on fully processed bipolar junction transistors at room temperature. This work indicates that the unparalleled analytical power of electron-nuclear double resonance in the identification of paramagnetic point defects can be exploited in the study of defects within fully functional solid-state electronic devices.
ChemInform Abstract: CHEMISTRY OF HIGHER ORDER, MIXED ORGANOCUPRATES. 3. REACTIONS OF α,β‐UNSATURATED KETONES (1983)

Abstract Kupfer(I)‐cyanid‐Komplexe wie (II) reagieren mit α,β‐ungesättigten Ketonen zu gesättigten β‐substituierten Ketonen.
Design of wideband microstrip array antennas using the coupled lines (2002)

A variety of single layer wideband microstrip antenna designs (e.g., parasitic structure, embedding slot, reactive loading, etc.) have been reported. The wideband impedance matching technique can also increase the bandwidth of microstrip antenna on a single layer, but this technique has a complicated design procedure and the disadvantage of increasing the coplanar size of the antenna due to the wideband impedance matching section. If the wideband impedance matching technique is applied to antenna arrays, the enlargement of coplanar size can be overcome by the inherent space between the array elements. In this article, we present two different designs of wideband microstrip array antennas using the coupled lines that are a kind of wideband impedance matching technique and are adequate for array antennas. Antenna designs and details of the experimental results are described and discussed.
Intermediate Purity Factor VIII by the Thaw-Siphon Cryoprecipitate Procedure (1979)

The procedure begins with the separation of a 220 ml plasma donation into a plastic pack fitted with an internal siphon tube, which is an extension of the external tube connected to the satellite pack. The tube is arranged in an L-shaped configuration with one section aligned along the side edge of the pack, and the continuation along the bottom edge of the pack; the latter has perforations at regular intervals. The donation is frozen as a flat slab at -40°C, and is, subsequently, thawed in an upright position in a 3–5°C water bath, with continual siphoning of thawed phase into the attached satellite pack. This proceeds for 40-50 minutes, when the frozen mass has reduced to a matrix, 5-10 ml in volume, of essentially pure ice trapping the cryoprecipitate. Citrate saline is introduced to dissolve the cryoprecipitate. The procedure has been characterized by measurements of conductivity and protein, in eluant fractions, whilst investigation of the product for Factor VIIIC, total protein and fibrinogen, give respectively 150 u, 350 mg and 125 mg, i.e. 0.43u/mg protein.
Sonar resolution-based environment mapping (2002)

Ultrasonic range sensors are used to obtain the information required for collision-free navigation of a mobile robot in a semi-structured or unstructured environment. A set of range readings from a ring of sonars are correlated to acquire a 2D map of the robot's environment. The map is continuously enhanced via novel matching and update algorithms as new data are collected while the robot is in motion. The algorithm utilizes confidence measures that are directly obtained from the sonar's resolution or accuracy. There are no additional modeling assumptions and the approach is robust. The algorithms are experimentally tested on the Nomad 200 mobile robot and Nomad's Cognos Software Development Package.
Mammalian Target of Rapamycin Repression by 3,3′-Diindolylmethane Inhibits Invasion and Angiogenesis in Platelet-Derived Growth Factor-D–Overexpressing PC3 Cells (2008)

Platelet-derived growth factor-D (PDGF-D) is a newly recognized growth factor known to regulate many cellular processes, including cell proliferation, transformation, invasion, and angiogenesis. Recent studies have shown that PDGF-D and its cognate receptor PDGFR-beta are expressed in prostate tumor tissues, suggesting that PDGF-D might play an important role in the development and progression of prostate cancer. However, the biological role of PDGF-D in tumorigenesis remains elusive. In this study, we found that PDGF-D-overexpressing PC3 cells (PC3 cells stably transfected with PDGF-D cDNA and referred to as PC3 PDGF-D) exhibited a rapid growth rate and enhanced cell invasion that was associated with the activation of mammalian target of rapamycin (mTOR) and reduced Akt activity. Rapamycin repressed mTOR activity and concomitantly resulted in the activation of Akt, which could attenuate the therapeutic effects of mTOR inhibitors. In contrast, B-DIM (BR-DIM from Bioresponse, Inc.; a chemopreventive agent) significantly inhibited both mTOR and Akt in PC3 PDGF-D cells, which were correlated with decreased cell proliferation and invasion. Moreover, conditioned medium from PC3 PDGF-D cells significantly increased the tube formation of human umbilical vein endothelial cells, which was inhibited by B-DIM treatment concomitant with reduced full-length and active form of PDGF-D. Our results suggest that B-DIM could serve as a novel and efficient chemopreventive and/or therapeutic agent by inactivation of both mTOR and Akt activity in PDGF-D-overexpressing prostate cancer.
20-HETE promotes glucose-stimulated insulin secretion in an autocrine manner through FFAR1 (2018)

The long-chain fatty acid receptor FFAR1 is highly expressed in pancreatic β-cells. Synthetic FFAR1 agonists can be used as antidiabetic drugs to promote glucose-stimulated insulin secretion (GSIS). However, the physiological role of FFAR1 in β-cells remains poorly understood. Here we show that 20-HETE activates FFAR1 and promotes GSIS via FFAR1 with higher potency and efficacy than dietary fatty acids such as palmitic, linoleic, and α-linolenic acid. Murine and human β-cells produce 20-HETE, and the ω-hydroxylase-mediated formation and release of 20-HETE is strongly stimulated by glucose. Pharmacological inhibition of 20-HETE formation and blockade of FFAR1 in islets inhibits GSIS. In islets from type-2 diabetic humans and mice, glucose-stimulated 20-HETE formation and 20-HETE-dependent stimulation of GSIS are strongly reduced. We show that 20-HETE is an FFAR1 agonist, which functions as an autocrine positive feed-forward regulator of GSIS, and that a reduced glucose-induced 20-HETE formation contributes to inefficient GSIS in type-2 diabetes.
Feminist Pedagogy in Our Classrooms and Our Communities (2016)

Please click the links below to view more information about each presentation. “‘The Feminist History Your Momma Never Taught You’ and its Necessary Inclusion in WGS Intro Classes” Katherine E. Ayers, Virginia Polytechnic Institute and State University “#TheStandardsAren'tEnough: Feminist Pedagogy and Teaching Intersectional Feminist Texts in the High School Classroom" Justine D. Chew, University of North Carolina at Wilmington “The US Community College as "Stepping Stone" to Opportunity for Asian/Asian American Women” Suchitra Samanta, Virginia Polytechnic Institute and State University “Intersectional Action-Learning: A Framework for Queer Capacity Building” Jayke A. Hamill, University of North Carolina at Greensboro
AIDS in Africa: A Manual for Physicians (1992)

The first reported AIDS cases in Africa occurred in central Africa in 1982. AIDS is rapidly spreading among the population living there as well as among populations in southern and western Africa. The AIDS pandemic is overtaxing an already burdened health system in sub-Saharan African countries. WHO has put together this manual so health workers in Africa could have a reliable source of current information in this new and rapidly expanding field. The manuals introduction discusses the public health and social significance of AIDS and provides some HIV seroprevalence rate (e.g. <1-20% of the general population 27-88% of female prostitutes in some cities). The manual next covers the etiology and pathogenesis of AIDS the human immunodeficiency virus (HIV) being the causative agent. Chapter 3 reviews the epidemiology of HIV infection and AIDS including an historical review of AIDS in Africa and transmission. Clinical manifestations of acute retroviral illness and asymptomatic and symptomatic HIV infection are delineated in Chapter 4. Opportunistic infections (fungal parasitic bacterial and viral infections) Kaposis sarcoma and lymphoma make up Chapter 5. Considerable information exists in Chapter 6 on HIV infection in children. Chapter 7 reviews clinical and laboratory diagnoses of HIV infection and AIDS. The most involved chapter in the manual is Chapter 8 which provides guidance on the management of HIV/AIDS patients. Counseling and psychosocial support is covered in Chapter 9. The manual concludes with a chapter on the prevention and control of HIV/AIDS. The annexes include the CDC 1987 revision of the case definition for AIDS for surveillance purposes and the CDC classification system for HIV infection.
High Quality On-Chip Long Annular Josephson Junction Clock Source for Digital Superconducting Electronics (2005)

We have developed clock sources for rapid single flux quantum (RSFQ) digital circuits using high-quality long Josephson junction (LJJ) resonant oscillators of annular geometry. Being a topologically closed system and unperturbed by reflections from boundaries and collisions among the fluxons (flux quanta), the annular LJJ oscillator has demonstrated a high quality factor. The novel design of an annular junction clock that allows easier interface with RSFQ circuitry has been realized. Magnetic fluxons are inserted into an annular LJJ by local injection of current into the control line of the junction. This technique resolves the long-standing problem of achieving superior stability of the fluxon state for application as a clock source. The linewidth of the phase-locked clock source is measured as low as 24 Hz relative to a reference oscillator at 40 GHz. The cycle-to-cycle jitter was measured to be 9 fs at a frequency of 36 GHz, or 0.04% of the clock period which is in good agreement with theoretical estimation.
Local Anesthetic Microcapsules. (1981)

Abstract : Three kilograms of poly-L(-)lactide has been synthesized for this contract and for Contract No. DAMD 17-80-C-0093. This polymer has a viscosity (R.S.V.) of 1.19 dl/g, a molecular weight (MWw) of 45,700 and a polydispersity of 2.14. Materials from a previous contract was used for preliminary experiments. Both lidocaine (HC1) and etidocaine (HC1) have been successfully micro-encapsulated using the Wurster coating process. Samples were taken at 10, 20, 30, 40, and 50% polymer loading (60% also for etidocaine). These samples were sieved and various size fractions were analyzed for drug release. Large microcapsules containing 50% lidocaine are required to delivery drug in vitro at the target rate (e.g. 150-212 micrometer deliver 36% in 1 hour, 54% in 2 hours, 72% in 4 hours, and 82% in 6 hours). Etidocaine microcapsules deliver 17% in 1 hour, 24% in 2 hours, 39% in 4 hours, and 48% in 6 hours). Appropriate samples are being stored for stability testing. Microcapsules from a previous program were used to develop animal model studies. Both lidocaine and etidocaine an be measured in blood by gas chromatography. Tactile response was measured after subcutaneous implantation of lidocaine crystals (neat) and microcapsules.
ChemInform Abstract: Synthesis and Characterization of Tetramethylammonium Trifluorosulfate. (2011)

Abstract (Me 4 N)[SO 2 F 3 ], the first example of a [SO 2 F 3 ] ‐ salt, is prepared by condensing SO 2 F 2 and MeCN at ‐196 °C into a quartz ampule containing Me 4 NF, followed by warming to room temperature (ultrasonic bath, a few hours, ≈100% yield).
The Role of Alanine and Serine in Hepatic Gluconeogenesis (1972)

Journal Article The Role of Alanine and Serine in Hepatic Gluconeogenesis Get access Eiji ISHIKAWA, Eiji ISHIKAWA The Division of Protein Metabolism, Institute for Protein Research, Osaka UniversitySuita, Osaka Search for other works by this author on: Oxford Academic PubMed Google Scholar Tadaomi AIKAWA, Tadaomi AIKAWA The Division of Protein Metabolism, Institute for Protein Research, Osaka UniversitySuita, Osaka Search for other works by this author on: Oxford Academic PubMed Google Scholar Hisako MATSUTAKA Hisako MATSUTAKA The Division of Protein Metabolism, Institute for Protein Research, Osaka UniversitySuita, Osaka Search for other works by this author on: Oxford Academic PubMed Google Scholar The Journal of Biochemistry, Volume 71, Issue 6, June 1972, Pages 1093–1095, https://doi.org/10.1093/oxfordjournals.jbchem.a129861 Published: 01 June 1972 Article history Received: 10 January 1972 Published: 01 June 1972