gebhart/patrepeval huggingface dataset:
Cotton/silk blends on cotton spinning process (2004)

After raw silk reeling in the silk industry, there remains 20-25% waste. This short silk fiber waste could be blended with other fibers, such as cotton fibers, to develop a new yarn with some new functional properties. Generally, there are three types of silk waste - inferior knobs, filature gum waste, and pierced cocoon - which correspond respectively with the outer, middle, and mixed layer of the cocoon. In this work, a complete study of blending is carried out in order to understand the influence of blending factors, which are the important parameters cited by Hamilton et al. (1958) for the blended yam. The blending type in the spinning process, the silk waste types, and the silk content has affected on the silk/cotton blended yam characterization. The distinctive properties of silk give to the blended yam a higher tenacity and better evenness.
A Novel Motif in HIV-1 Nef That Regulates MIP-1β Chemokine Release in Macrophages (2010)

All primate lentiviruses encode Nef, an accessory protein that is important for viral pathogenicity in vivo. Lentiviral Nef proteins regulate the release of chemokines (MIP-1 alpha/beta) from infected macrophages, thereby enhancing virus dissemination (S. Swingler, A. Mann, J. Jacque, B. Brichacek, V. G. Sasseville, K. Williams, A. A. Lackner, E. N. Janoff, R. Wang, D. Fisher, and M. Stevenson, Nat. Med. 5:997-1003, 1999). In the current study, we have identified a novel domain within Nef (K(92)EK) that is required for Nef-dependent MIP-1beta production by infected macrophages. Mutations in this domain abrogated MIP-1beta induction but did not affect other Nef-ascribed activities, such as CD4 or major histocompatibility complex (MHC) class Iota downregulation. This further underscores Nef as a modular protein with genetically separable activities that may contribute to its role in viral replication and pathogenicity.
Adenosquamous carcinoma, a rare and unknown tumor (2018)

Introduction: Adenosquamous carcinoma (ASC) of the head and neck is a rare malignant tumor, with one hundred cases diagnosed so far in the literature. Observation: A 66 years old female patient had a ASC of the right posterior floor of the mouth with a classification T1N0M0. Treatment consisted of surgical management and active surveillance. Discussion: Through this case report, we present this type of tumor and we discuss the main differential diagnosis from a clinical and histological point of view. Conclusion: This entity was described for the first time in 1968 by Gerughty. The CAS is defined by the World Health Organization as “a tumor of the upper respiratory tract, with two distinct squamous and glandular components.” The CAS is considered as an aggressive tumor with a redoubtable prognosis should not be ignored.
Information to authors. Presentation of articles (1994)

The instructions below are separated into three categories. Sciences et Techniques Educatives publisher would be grateful to authors for respecting these indications. In your article, the length of this abstract may attain a dozen lines written in italic Times size 9. An abstract in French must be joined.
Biphasic Chemistry Utilising Ionic Liquids (2005)

Biphasic and multiphasic processes have emerged as effective methods to reduce the amount of volatile organic solvents used in the manufacture of chemicals. In this article some of the research conducted in my laboratory in this domain utilizing ionic liquids is described. Other dimensions to our research interests in ionic liquids are also discussed including their conversion to porous nanomaterials.
MUVOT - ESTABLISHING AN INTERNATIONAL VOCATIONAL TRAINING PROGRAM ON THE TOPIC OF MEASUREMENT UNCERTAINTY (2013)

Measurement results represent important information, which are necessary for evaluating and improving the quality of manufactured products and to control manufacturing processes. Furthermore, they build the basis for numerous decisions in the field of quality management, process and production automation or product development and design.\nKnowledge about the acquisition, evaluation and interpretation of measurement data as well as an understanding of the relevant influences on those measurement results are essential for employees working in the field of manufacturing metrology. Measurement results are always afflicted with deviations, due to a variety of causes. It follows that in order to assign a value to the reliability and quality of a measurement result its uncertainty must be determined and considered. However, employees in the field of quality management or metrology are often not familiar with methods for determination and interpretation of measurement uncertainty, because appropriate opportunities for training are missing in current vocational education.\nThis need has led to the creation of the European project MUVoT, which will create a course for advanced vocational training in determining measurement uncertainty. The training course is based on a blended learning concept, combining self-dependent learning via a web-based platform and face-to-face workshops. This allows the adaption of individual knowledge and skills by self-controlled learning of abstract contents whilst the exercises enable the practical application of typical methods, which are generally considered as quite complex by many employees, and thus assure correct understanding. The featured Blended Learning concept facilitates the integration of the training into a workplace setting, thus the idea of Lifelong Learning is promoted in new fields of application. The curriculum and training concept for this newly developed training program have been designed such that the course can be applied internationally. To facilitate this, a harmonized scheme for course structure and contents has been defined albeit with inherent flexibility, allowing the adaptation to specific constraints.
Catalytic Activity of the SH2 Domain of Human pp60c-src; Evidence from NMR, Mass Spectrometry, Site-Directed Mutagenesis and Kinetic Studies for an Inherent Phosphatase Activity (1995)

During solution structural studies it was apparent that the human recombinant pp60c-src SH2 domain (srcSH2, residues 144-249) possessed an inherent phosphatase (Pase) activity. Complexes of U[13C,15N]srcSH2 with unlabeled Ac-pYEEIE (I) were examined using 31P and 1H-detected isotope filtered NMR methods. The presence of a high-affinity complex in equimolar solutions of I and U[13C, 15N]-srcSH2 was demonstrated by chemical shift perturbations, line broadening, and the observation of intermolecular nuclear Overhauser effects from the pY and Ile side-chain protons of I to protons on amino acid residues present in the binding pocket of srcSH2. Solutions containing excess I relative to srcSH2 revealed a slow hydrolysis of I to produce Ac-YEEIE and inorganic phosphate. The hydrolysis rate determined from NMR and HPLC-electrospray ionization mass spectrometry data at 30 degrees C for solutions containing excess I was 0.002-0.003 h-1. srcSH2 also catalyzed the hydrolysis of p-nitrophenyl phosphate (pNPP). Isoelectric focusing gels of a number of mutant srcSH2s demonstrated that this activity comigrated with srcSH2. Km, kcat, and kcat/Km were 3.7 +/- 0.4 mM, 3.1 +/- 0.2 x 10(-2) min-1, and 8.4 +/- 0.4 M-1 min-1, respectively, toward pNPP. The C188A mutant of the srcSH2 domain displayed 15% of the activity displayed by wild-type srcSH2, demonstrating that this residue is not absolutely required for activity. Two additional mutations in the known pY binding site, R178K and R158K, also resulted in decreased pNPPase activity, suggesting that the activity resides in or near this site. The inhibitor profile and pH dependence suggest that this is a novel protein Pase activity.(ABSTRACT TRUNCATED AT 250 WORDS)
Temporal Evolution of Coronagraphic Dynamic Range and Constraints on Companions to Vega (2006)

The major obstacle to the direct detection of companions to nearby stars is the overwhelming brightness of the host star. Current instruments employing the combination of adaptive optics (AO) and coronagraphy can typically detect objects within 2'' of the star that are 10^{4-5} times fainter. Correlated speckle noise is one of the biggest obstacles limiting such high-contrast imaging. We have obtained a series of 284 8 s, AO-corrected, coronagraphically occulted H-band images of the star Vega at the 3.63 m AEOS telescope located on Haleakala, Hawaii. This dataset is unique for studying the temporal behavior of speckle noise, and represents the first time such a study on highly corrected _coronagraphic_ AO images has been carried out in a quantitative way. We find the speckle pattern to be highly stable in both position and time in our data. This is due to the fact that the AO system corrects disturbances to the stellar wave front at the level where the instrumental wave front errors dominate. Because of this, we find that our detection limit is not significantly improved simply with increased exposure time alone. However, we are able to improve our dynamic range by 1.5-2 magnitudes through subtraction of static/quasi-static speckles in two rotating frames: the telescope pupil frame and the deformable mirror frame. Furthermore, from our data, we are able to constrain the mass of any purported companion to Vega to be less than 45 M_J at 8 AU and less than 30 M_J at 16 AU, radii not previously probed at these sensitivities.
Ultrastructural and Biochemical Evaluation of Adrenal Medullary Hyperplasia and Pheochromocytoma in Aged Bulls (1981)

Pheochromocytomas and adrenal medullary hyperplasia were investigated ultrastructurally and by assaying catecholamines in tissue and urine. Three of seven bulls had concomitant thyroid C-cell neoplasms and normal parathyroid glands. Pheochromocytomas were either bilateral or unilateral, and were composed of large chromaffin cells predominantly in the storage phase of the secretory cycle. Two pheochromocytomas were composed of cells with ultrastructural characteristics of the epinephrine-secreting type and contained round secretory granules of low electron density. The norepinephrine-secreting type of chromaffin cell predominated in one pheochromocytoma and had storage granules with an electron-dense, eccentric core and a wide submembranous space. Two pheochromocytomas were composed of a mixture of epinephrine- and norepinephrine-secreting cells. Adrenal medullary hyperplasia in four bulls consisted of multinodular or diffuse areas of hyperchromatic chromaffin cells that were non-encapsulated, and compressed adjacent cortical tissue. Tissue and urinary concentrations of norepinephrine were increased in bulls with adrenal medullary hyperplasia or pheochromocytoma, but urinary vanillylmandelic acid and unconjugated epinephrine levels were not different from those of control bulls with a normal adrenal medulla.
Cyclosporin Inhibits Cardiomegaly in the Conditional, Cardiac GCaMP2 Mice (2006)

Mice expressing the Ca2+ sensor protein GCaMP2 in cardiac myocytes under the control of a doxocycline -regulated αMHC promoter (ccGC2 mice) develop cardiomegaly by 14 weeks. As the transgene consists of a calmodulin – eGFP chimeric protein, we performed initial experiments to examine the mechanism(s) underlying the development of cardiac hypertrophy. Previous observations suggest that the overexpression of calmodulin can lead to hypertrophic cardiomyopathy (Gruver et al Endocrin 1993), suggesting a possible activation of the calcineurin/nFAT pathway (Dong et al Cardio Res 2003, Molkentin et al Cell 1998). We examined whether inhibiting the activation of this pathway prevented GCaMP2 dependent development of cardiac hypertrophy. Beginning at post natal day 7, wildtype and ccGC2 litter mate controls were injected with either vehicle only or cyclosporin (10–20mg/kg) twice daily for two weeks. Mice were euthanized at 3 weeks of age, at which time heart and body weight were measured. The heart to body weight ratio in 3 week old ccGC2 mice injected with vehicle was 15% greater than vehicle injected wildtype mice or ccGC2 mice injected with cyclosporin A (5.8 ± 0.2 n=5; 5.1 ± 0.2 n=5; 5.2 ± 0.1 n=7 p < 0.02, respectively). Cardiomegaly was inhibited in ccGC2 mice injected with cyclosporin A when compared to cyclosporin A injected wildtype litter mate controls (5.2 ± 0.1 n=7; 5.3 ± 0.1 n=6, respectively). These data suggest that GCaMP2 transgene expression produces cardiac hypertrophy through stimulation of of calcineurin pathway. As the transgene is temporally regulated, ccGC2 mice may be useful in examining the signaling processes leading to the development of cardiomegaly in adult mice. Values are ± SE. NIH grants HL45239 and DK58795.
Muon Spin Rotation Studies of Spin Dynamics at Avoided Level Crossings in<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:msub><mml:mi>LiY</mml:mi><mml:mn>0.998</mml:mn></mml:msub><mml:msub><mml:mi>Ho</mml:mi><mml:mn>0.002</mml:mn></mml:msub><mml:msub><mml:mi mathvariant="normal">F</mml:mi><mml:mn>4</mml:mn></mml:msub></mml:math> (2007)

We have studied the Ho3+ spin dynamics for LiY0.998Ho0.002F4 via the positive muon (mu+) transverse field depolarization rate lambdaTF as a function of temperature and magnetic field. We find sharp minima in lambdaTF(H) at fields for which the Ho3+ ion system has field-induced (avoided) level crossings. The reduction scales with calculated level repulsions, suggesting that mu+ depolarization by slow fluctuations of nonresonant Ho3+ spin states is partly suppressed when resonant tunneling opens new fluctuation channels at frequencies much greater than the muon precession frequency.
The influence of antiserotonergic agents on the action of dopaminergic drugs. (1977)

The effect of drugs blocking serotonin receptors: cyproheptadine, methysergide, and methergoline, and of serotonin synthesis inhibitor, p-chlorophenylalanine on the stereotyped behavior and number of rearings of the rats receiving apomorphine, amphetamine, nomifensine and 1,3-dimethyl-5-aminoadamantane was investigated. The blockade of serotonin receptors potentiates behavioral effects of dopamine agonists. It is concluded that central serotonin may play an inhibitory role, antagonistic to that of catecholamines.
The Role of Inflammatory Mediators in the Mechanism of the Host Immune Response Induced by Ischemia-Reperfusion Injury (2000)

Our previous study suggested that inflammatory mediators released due to IRI lead to host's immune response by upregulating MHC II in the host's peripheral T lymphocytes. This study hypothesized the role of platelet-activating factor (PAF) in the mechanism of induced MHC II upregulation due to IRI on peripheral T lymphocytes. The objectives of this study were to investigate the role of PAF in the induction of host immune reactivity and the protective effect of PAF-antagonist TCV-309 in combination with prostaglandin E1 (PGE1) against the host's immune response caused by IRI. Thirty female domestic swine were divided into three groups. Group A (6 donors, 6 recipients) had no pharmacological intervention. Group B (6 donors, 6 recipients) was the experimental group treated with TCV-309 + PGE1. Group C underwent sham operation. The ex vivo preservation time for groups A and B was 4 hr at 4 degrees C. To detect the changes in MHC II expression on T cells due to IRI, blood samples were collected before reperfusion (baseline level), 1, 2, and 3 days post-reperfusion. Two-colour flow cytometry analysis (FACS) was used to study MHC II-DR-beta expression in peripheral T lymphocytes. Swine anti-MHC II and anti-CD3 antibodies were used for this purpose. The FACS analyses demonstrated that in group A, there was a significant increase (p < 0.05) in MHC II intensity on peripheral T lymphocytes on day 2 post-reperfusion. By the third day post-reperfusion, MHC intensity had a tendency to decrease but did not reached the baseline level. In group B and C, however, there was no significant change in the level of MHC II in T lymphocytes at any of the post-reperfusion times. In group A, the number of CD3+MHC+ T lymphocytes significantly decreased (p < 0.05) by one day post-reperfusion and remained at this level until the third day post-reperfusion. In groups B and C, no significant change in the number of CD3+MHC+ T cells was observed. The results of this study suggested that the release of inflammatory mediators (e.g. PAF) due to IRI played a role in the mechanism of IRI-induced host's immune response. The results also suggested that the combination of TCV-309 + PGE1 could reduce this immune response.
Expression of the activation marker urokinase plasminogen-activator receptor in cultured human central nervous system microglia (1996)

The ability of microglia to migrate through central nervous system (CNS) tissue requires proteolytic degradation of components of the extracellular matrix. Urokinase plasminogen activator (uPA), when bound to its cell surface receptor (uPAR), is an active cell surface protease. uPAR expression has been associated with cell activation. Cultured human microglia express surface uPAR. uPAR expression was found to be associated predominately with spindle- or bipolarshaped microglia. The addition of lipopolysaccharide (LPS) to microglial cultures enhanced the proportion of uPAR expression and shifted cell morphology to the elongated spindle or bipolar shape. When microglia were examined immediately ex vivo, uPAR surface expression could not be detected. Similarly, uPAR transcripts detected by reverse transcription-polymerase chain reaction techniques were found in cultured, but not ex vivo, microglia. Microglia isolated from a patient with multiple sclerosis (MS) displayed a large amount of uPAR+ cells. These cells were predominantly spindle or bipolar in nature. These findings suggest that uPAR surface expression is associated with microglial activation. Surface expression of uPAR and associated cell surface protease activity may provide a mechanism for microglial migration and may be important in the pathophysiology of MS.
Study of potassium DPAL operation in pulsed and CW mode (2014)

This paper presents the results of our experiments on development of the efficient hydrocarbon free Diode Pumped Alkali Laser based on potassium vapor buffered by He gas at 600 Torr. We studied the performance of this laser operating in pulsed mode with pulses up to 5 ms long at different pulse energies and cell temperatures. A slope efficiency of more than 50% was demonstrated with total optical efficiency about 30% for the pump pulses with duration about 30 μs. For the longer pump pulses the DPAL efficiency degraded in time with a characteristic time in the range from 0.5 ms to 4.5 ms depending on the pump pulse energy and cell temperature. The recorded spectrum of the side fluorescence indicates that multi-photon excitation, energy pooling collisions and ionization may be strong candidates for explaining the observed performance degradation.
The Use of Autografts for Vertebral Body Replacement of the Thoracic and Lumbar Spine (1985)

Thirty-seven patients with fractures of the thoracic or lumbar spine underwent anterior corpectomy (partial or complete) and vertebral body replacement for either destructive lesions from tumor or infection (13 patients) or trauma (24 patients). The vertebral bodies were replaced using either rib (12 patients) or tricortical iliac crest (25 patients) autografts. The Dunn device was utilized in conjunction with the autografts in 19 patients. Posterior stabilization was used in five patients; three prior to anterior stabilization and two after anterior stabilization. Within 2 weeks of the operative procedure, all patients began walking or sitting. Of the 37 patients, 21 with incomplete neurologic deficits improved, and 10 of those went onto complete recovery. Of the 27 patients who have been followed for a minimum of 1 year, 25 have obtained solid fusions, one developed a pseudarthrosis that required regrafting, and one had a delayed union prior to death from metastatic disease. There were two deaths in the immediate postoperative period and three deaths in the first six postoperative wounds due to metastatic disease. The purpose of this study is to present a consecutive series of patients who have undergone corpectomy and vertebral body replacement as well as to define the adequacy of stabilization.
EMTP Model of Anti-Earthquake Building Stroked by Lightning (2006)

This paper models an anti earthquake building during lightning stroke to the building. The transient voltages due to lightning of modeled building at the connection point between the building and ground base are investigated to study the effect of the connection wire between the building and grounding base of the building. Lightning current was injected into the vertical pillar A top of the building. The transient voltages due to lightning at the top of the building at vertical pillar A with roof connection and vertical pillar A with first floor connection were observed and discussed. The modeling for different cases and discussion show good results, and agree with the physical meaning of real cases. The maximum voltage at first floor depends on pillars base grounding resistance and connection wires. The effect of varying connection wire inductance for different grounding resistance on first floor maximum voltage show that as the connection wire inductance increases, the first floor maximum voltage increases.
<i>In vivo</i>analysis of plant pre-mRNA splicing using an autonomously replicating vector (1991)

In this paper, we demonstrate that an autonomously replicating plant expression vector can be used for analysis of pre-mRNA splicing determinants in intact dicot cells. This vector system relies on the Agrobacterium-mediated transfection of leaf discs with the A component of the geminivirus tomato golden mosaic virus (TGMV). Insertion of intron sequences between viral promoter and terminator sequences results in the production of high levels of pre-mRNA transcripts that are effectively and accurately spliced in vivo. Introns from the soybean B-conglycinin gene are spliced at greater than 95% efficiency indicating that the high expression levels of precursor RNA do not exceed the intron splicing capacity of these cells. Introns from the pea and wheat rbcS genes are spliced at 85% and 73% efficiency, respectively, indicating that tobacco leaf disc nuclei are capable of effectively and accurately processing particular dicot and monocot introns. Inclusion of a dicot intron in an engineered construct results in a five-fold enhancement of the level of mRNA stably expressed in dicot nuclei.
Prescreening Evaluation of a Brush-Based Faecal Immunochemical Test for Haemoglobin (2003)

InSure is as sensitive and specific as FlexSure OBT for faecal haemoglobin. The novel stool-sampling method of InSure allows discrimination between normals and classes of neoplasia, and is highly preferred. The brush-sampling faecal immunochemical test InSure should now be evaluated in a screening population.
Chapter 6. Interactions involving aquo ions (1971)

D. R. Rosseinsky, Annu. Rep. Prog. Chem., Sect. A. Gen. Phys and Inorg. Chem., 1971, 68, 81 DOI: 10.1039/GR9716800081
The synthesis of phthalocyanines containing both nitrile and non-peripheral alkyl or alkoxy side-chains (2003)

The synthesis of a number of phthalocyanines containing four or eight peripheral nitrile groups in addition to eight non-peripheral alkyl or alkoxyl side-chains is described. These materials are derived from the tetracyano- and tricyano-benzene derivatives prepared by the Rosenmund von Braun reaction of 1,2,4,5-tetrabromo-3,6-didodecylbenzene or 1,2,4,5-tetrabromo-3,6-hexyloxybenzene. Attempts to polymerise 1,2,4,5-tetracyano-3,5-didodecylbenzene to form a soluble polyphthalocyanine derivative failed.