gebhart/patrepeval huggingface dataset:
The Adaptation of Two Human Coronavirus Strains (OC38 and OC43) to Growth in Cell Monolayers (1970)

SummaryTwo human coronaviruses, strains OC38 and OC43, were successfully adapted to growth in tissue culture monolayers. The adapted strains produced a cytopathic effect in primary rhesus or vervet monkey kidney and in BSC-1 cell monolayers. The adaptation described will facilitate further investigations of the structure of coronaviruses.
Suppression of Nonlinear Rotary Slosh Dynamics using the SLS Adaptive Augmenting Control System Demonstration on a Quadcopter Testbed (2019)

Liquid propellant makes up a significant portion of the total weight for large launch vehicles such as Saturn V, Space Shuttle, and the Space Launch System. Careful attention must be given to the influence of fuel slosh motion on the stability of the vehicle in the design of the Flight Control System (FCS). Historically, there have been instances where a poorly designed FCS in addition to a lack of passive damping have caused the slosh mass to drive the launch vehicle unstable. The dynamics behind controlling a quadcopter/hanging mass configuration is analogous to that of controlling the attitude of a rocket with a single propellant tank. The quadcopter/hanging mass configuration offers a reasonably accurate platform for assessing the real-time effectiveness of the SLS Adaptive Augmenting Controller in suppressing slosh instability. Flight test experiments were carried out at the NASA Langley Research Center's Autonomy Incubator. During both simulation and flight test, the hanging mass was intentionally made unstable and the adaptive algorithm successfully suppressed the instability as expected.
Structural and optical characterization of wurtzite Al 0.8 In 0.2 N thin films grown by low temperature magnetron sputter epitaxy (2006)

Single-crystal ternary wurtzite Al<sub>0.8</sub>In<sub>0.2</sub>N thin films were grown epitaxially onto lattice-matched (111)-oriented Ti<sub>0.2</sub>Zr<sub>0.8</sub>N seedlayers. The epilayers were grown onto single-crystal MgO (111) substrates by magnetron sputter epitaxy (MSE) using reactive direct current magnetron sputtering in an N<sub>2</sub> discharge under ultra-high-vacuum conditions. The growth temperatures ranged from 20 to 700 <sup>o</sup>C. Low-energy ion-assisted growth conditions, enhancing the epitaxy, were achieved by applying a negative substrate potential of 15-45 V. Film compositions and lattice parameters were determined using Rutherford Backscattering Spectroscopy (RBS) and High-Resolution X-ray diffraction (XRD), respectively. Cross-sectional High-Resolution Electron Microscopy of the interface regions verified the epitaxy and the crystallinity of the films. XRD ω-rocking scans of the Al<sub>0.8</sub>In<sub>0.2</sub>N 0002-peak showed full-width-at-half-maximum values of ~2400 arcs, indicating a high structural quality of the films. Opto-electronical properties were studied by cathodoluminescence at temperatures between 5 and 293 K. Luminescence was observed at wavelengths as short as 248 nm, corresponding to an energy of 5.0 eV. These results point towards the feasibility of metastable Al<sub>0.8</sub>In<sub>0.2</sub>N solid solutions as an active luminous material in opto-electronics. It also shows that MSE-grown Al<sub>0.8</sub>In<sub>0.2</sub>N can be an excellent choice for lattice-matched GaN heterostructures, with a resulting energy band-gap difference enabling strong charge carrier confinement. In addition to these new and original results, a brief review of the present work on Al(<sub>1-x</sub>)In<sub>x</sub>N growth at Linkoeping University is presented.
Abstract 2461: Low Thromboembolism and Pump Thrombosis Potential of the HeartMate II (HM) LVAD (2007)

Introduction: The HM continuous flow LVAD has been shown to have good reliability and an excellent safety profile when used as a bridge to transplantation (BTT). Initially, there were concerns that the continuous flow and design of the HM might pre-dispose patients to thromboembolic events or pump thrombosis and therefore oral anticoagulation with coumadin was recommended. Our study evaluates the risk of thromboembolism and pump thrombosis related to the degree of anticoagulation as reflected by the International Normalized Ratio (INR). Methods: We evaluated all patients enrolled in the HM BTT pivotal trial from 1 to 6 months post-implant in order to eliminate perioperative events unrelated to anticoagulation. All patients were on aspirin and some also on persantine. An INR was measured monthly per protocol. Each individual INR sample from each time interval was assigned to ranges of INR values. Adverse events analyzed were ischemic (I) and hemorrhagic (H) stroke, pump thrombosis (T), and GI bleeding (G). Patients with adverse events were associated with the most recent INR at the start of the time interval. Results: The median duration of support for 189 patients was 132 days (range: 1–672 days) (cumulative: 96.9 patient years). There were 7 (3.7 %) patients with thrombotic events and 11 (5.8 %) patients with hemorrhagic events. The only pump thrombosis occurred with an INR > 2.5 (0.5 %). Conclusions: The rates of thromboembolism, including stroke and pump thrombosis appear to be low with the HM as BTT. The thrombotic events appear to be offset by an equivalent number of hemorrhagic events. There appears to be no correlation between the degree of anticoagulation with warfarin, as reflected by the INR, and the frequency of thrombotic or hemorrhagic events. Therefore, particularly in patients having recurrent episodes of bleeding, the risk of lowering the target INR appears to be small.
Cold storage of rat skeletal muscle free flaps and pre-ischemic perfusion with modified UW solution (2000)

We used the rat medial gastrocnemius free flap, based on a pedicle of the femoral artery and vein, in order to test the tolerance of skeletal muscle to cold ischemia-reperfusion (IR) injury, and to determine whether tolerance can be enhanced by pre-ischemic perfusion with tissue/organ preservation solutions. Muscle flaps (n = 6 per group) were subjected to variable periods of cold storage (0, 1, 2, 3, or 4 days) and 24-h normothermic reperfusion. Muscle viability, as determined by nitroblue tetrazolium (NBT) histochemical staining of viable mitochondria and supported by histological examination, was 100%, 26%, 11%, 4%, and 1%, respectively. Using 24-h cold storage/24-h reperfusion as the experimental conditions, groups of muscle flaps (n = 5 per group) were perfused immediately before cold storage with either modified, colloid-free University of Wisconsin (UW) solution, a solution described by Kohout et al. (Br J Plast Surg 1995;48:132-144) or normal saline. Perfusion with modified UW solution or Kohout's solution increased survival to 33% (P < 0.05) and 28% (not statistically significant), respectively, compared with the 19% viability of separate groups of nonperfused or saline-perfused controls. These findings indicate that cold-stored skeletal muscle is highly susceptible to cold IR injury and that the viability can be increased by prior perfusion with a tissue preservation solution such as modified UW solution.
Distributed dynamic-strain sensing based on brillouin optical correlation domain analysis (2009)

We study the influence of the integral time constant of signal processing in a modified Brillouin optical correlation domain analysis system to the interrogated strain. The synchronization control of the microwave synthesizer, the function generator and data acquisition enables 5-Hz entire distributed sensing with a capability of detecting 2-Hz distributed dynamic strain.
Damping characterisation of aluminium containing interconnected wire reinforcement using a novel frequency domain based method (2003)

In this study, an aluminium alloy, AA 1050, was reinforced with an interconnected, axisymmetrical, galvanised iron wire preform. The composite was synthesised using a conventional casting technique followed by hot extrusion. The composite was tested in a free - free type suspended beam arrangement, coupled with circle fit approach to determine damping characteristics. This testing method is based on classical vibration theory, by which the geometry and material properties of the metal matrix composites are related to the resonant frequency and structural damping of the test specimen. Using the fact that the ratio of the vibration response to the applied force fits to a circle in the Argand plane for each resonant frequency of the test specimen, the damping factor and natural frequency is predicted accurately for the test specimen. To demonstrate the accuracy of the test method, test results of a pure aluminium sample are compared against results from other test methods from published literature. Results of this study show that addition of about 5% of interconnected reinforcement increases the overall damping capacity of the aluminium matrix by ~ 17%. An attempt is made to correlate the increase in damping with the reinforcement associated microstructure variation of the aluminium matrix.
EFFECTS OF ELECTRICAL SYSTEM UNDERFREQUENCY TRANSIENTS ON PRESSURIZED WATER REACTORS. (1972)

High-schoolers (n=298) completed surveys describing the frequency and importance of mother and father communication about 20 different sex-related topics. There were four domains of sex-related topics: Development and Societal Concerns, Sexual Safety, Experiencing Sex, and Solitary Sexual Activity. Adolescents reported infrequent communication which varied by domain and gender of parent and teen. When communication occurred, it was most frequently about the first two domains. Mothers were reported as more frequent communicators about sexuality than fathers and girls received more communication than boys. Young people rated parental communication about sexuality as unimportant, with findings that paralleled those for frequency. Examination of the match between frequency and perceived importance of parental communication revealed more matches than mismatches. Almost all matches resulted from responses indicating low frequency and little importance. Most mismatches reflected a perception of insufficient rather than excessive parental communication about sexuality. It is argued that we need to consider the relative importance given to parental communication, as well as its frequency, if parents are to be effective communicators.
The structure of the blue luminescent δ-phase of tris(8-hydroxyquinoline)aluminium(<scp>iii</scp>) (Alq<sub>3</sub>) (2002)

The existence of the facial isomer in the delta-phase of Alq3 is proven by X-ray structural analysis, revealing that both the different molecular structure and the weaker overlap of the pi-orbitals of hydroxyquinoline ligands belonging to neighboring Alq3 molecules as compared to other phases (alpha, beta) are likely to be the origin of the significantly different optical properties of delta-Alq3.
Determination of the function of the internal branch of the superior laryngeal nerve after thyroidectomy (2007)

Although most patients report significant difficulty swallowing after thyroidectomy, the sensory nerve to the laryngopharynx remains intact and is not at risk during thyroid surgery.
Protamine Sulfate Inhibition of Serum-Induced Mitogenic Responses: Differential Effects on Normal and Neoplastic Cells<xref ref-type="fn" rid="FN2">2</xref> (1984)

Protamine sulfate reversibly inhibits serum-induced mitogenic stimulation of several nontransformed and neoplastic cell types in vitro. Fifty percent inhibition was induced by approximately 120-150 micrograms protamine sulfate/ml. Cells were affected directly, and inhibition depended on the duration of cell exposure. Heparin, chondroitin sulfate, heparan sulfate, and dextran sulfate neutralized protamine sulfate effects during the early stages of treatment. Nontransformed cells [bovine aortic endothelial cells, adult human gingival fibroblasts (strains 423 and 1101), fetal rat skin (strain 921-K) and muscle fibroblasts] required longer exposure to induce inhibition than did neoplastic cells [rat 3-methylcholanthrene-induced fibrosarcoma cell lines (MCA-6 and MCA-9), a macrophage-like cell line (NCTC-3749), Walker 256 rat carcinoma cells (ATCC-CCL-38), rat Morris hepatoma cells (ATCC-CCL-144), murine melanoma cells (B16), and rat bladder squamous cell carcinoma cells (804-G)]. Other polycationic compounds, including histone type VIII-S, poly-L-lysine, poly-L-arginine, and protamine (free base), were also effective inhibitors, whereas the basic proteins cytochrome c and lysozyme had no effect. Poly-L-histidine, poly-L-glutamic acid, poly-L-aspartic acid, and dextran blue also had no inhibitory effect.
Analysis of Berkovich Nanoindentation Loading Curves in SiC and SiO2 Materials (2007)

On two SiC ceramics and a standard fused silica specimen, depth-sensing indentation tests with a Berkovich indenter were carried out at several peak loads. The loading part of the load-displacement curves were statistically analyzed and it was shown that the loading exponent of the relation P ∝ hn was lower than the expected value of 2 in most of the cases. Factors affecting the loading exponent have been considered and evaluated. It was demonstrated that their effect was minimal on the fitting results.
Mechanism and stereochemical considerations in the reaction of some arylserine derivatives with thionyl chloride (1969)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTMechanism and stereochemical considerations in the reaction of some arylserine derivatives with thionyl chlorideSeemon H. Pines, Matthew A. Kozlowski, and Sandor KaradyCite this: J. Org. Chem. 1969, 34, 6, 1621–1627Publication Date (Print):June 1, 1969Publication History Published online1 May 2002Published inissue 1 June 1969https://pubs.acs.org/doi/10.1021/jo01258a019https://doi.org/10.1021/jo01258a019research-articleACS PublicationsRequest reuse permissionsArticle Views289Altmetric-Citations12LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Blocking autophagy to prevent parasite differentiation: A possible new strategy for fighting parasitic infections? (2008)

The genome of Trypanosoma cruzi was surveyed for autophagy-related genes. We have identified all the essential genes except for the Atg12 conjugation system and demonstrated functionality of the putative ATG4 and ATG8 homologs. TcAtg4.1 was primarily involved in the proteolytic processing of TcAtg8.1, the ATG8-homolog that was found to be localized to autophagosomal membranes during starvation. Autophagy was also found to be strongly upregulated during differentiation between developmental stages, a process that is essential for the propagation of the parasite. Based on our work, new strategies for treatment of Chagas disease, a chronic debilitating condition still without suitable chemotherapy, can be envisioned.
<i>In</i> <i>situ</i> real time studies of the formation of polycrystalline silicon films on glass grown by a layer-by-layer technique (1995)

The effect of atomic hydrogen on thin deposited layers of amorphous silicon was studied. Amorphous silicon layers less than 10 nm thick were first deposited from fluorinated precursors. These layers were then exposed to an atomic hydrogen flux. The amorphous layers quickly relaxed to a crystalline structure. Thick films of high crystalline content were prepared through sequential repetition of the deposition and hydrogen exposure process (layer-by-layer technique). The relaxation process was studied by real time in situ ellipsometry and infrared measurements. The relationship between substrate temperature, amorphous layer thickness, hydrogen exposure time, and structure was determined. A new model in which hydrogen acts to ‘‘liquify’’ the subsurface region by breaking Si–Si bonds is suggested. From the ‘‘liquidlike’’ state the subsurface relaxes to its most thermodynamically stable constituents; during relaxation, crystalline silicon is formed with effluence of SiH4, SiFxH4−x, and SiF4 vapors.
A Character Size Optimization Technique for Throughput Enhancement of Character Projection Lithography (2006)

We propose a character size optimization technique to enhance the throughput of maskless lithography as well as photomask manufacture. The number of electron beam shots to draw the patterns of circuits is a dominant factor in the manufacture time and the cost for devices. Our technique is capable of drastically reducing them by optimizing the size of characters, which are the patterns to project and are placed on CP masks. Experimental results show that our technique reduced 72.0% of EB shots in the best case, comparing with the ad hoc character sizing
An enhanced and embedded GNU radio flow (2014)

This paper presents a Zynq capable version of GNU Radio - an open-source rapid radio deployment tool - with an enhanced flow that utilizes the processing capability of FPGAs. This work features TFlow - an FPGA back-end compilation accelerator for instant FPGA assembly. The Xilinx Zynq FPGA architecture integrates the FPGA fabric and CPU onto a single chip, which eliminates the need for a controlling host computer; thus, providing a single, portable, low-power, embedded platform. By exploiting the computational advantages of FPGAs in the GNU Radio flow, a larger class of software defined radios can be implemented. Once the FPGA is programmed with a design, modules can be parameterized to realize an even larger class of applications and further solidify the concept of rapid assembly of software defined radios.
Facile N-O bond cleavages of amine oxides (1968)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTFacile N-O bond cleavages of amine oxidesAlain Ahond, Adrien Cave, Christiane Kan-Fan, Henri Philippe Husson, Jacques De Rostolan, and Pierre PotierCite this: J. Am. Chem. Soc. 1968, 90, 20, 5622–5623Publication Date (Print):September 1, 1968Publication History Published online1 May 2002Published inissue 1 September 1968https://pubs.acs.org/doi/10.1021/ja01022a063https://doi.org/10.1021/ja01022a063research-articleACS PublicationsRequest reuse permissionsArticle Views1304Altmetric-Citations84LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Persistence of staphylococcal cell-wall components in inflammatory sites may be due to the modulation by sulphated polyelectrolytes of autolytic wall enzymes: a working hypothesis. (1985)

The interaction of leucocytes with Staphylococcus aureus results in killing of the bacterial cells, but large portions of the bacterial cell walls persist apparently phagocytic cells for long periods. The mechanisms of biodegradation of staphylococci by leucocyte factors have shown that degradation of cell walls in vitro may be the result of the activation, by leucocyte kationic proteins, of the bacterial autolytic wall enzymes that are responsible for degrading the cell walls from within. This process is markedly inhibited by sulphated polysaccharides like dextran sulphate, by heparin, or by polyanetholesulfonate (liquoid). These anionic polyelectrolytes have also been shown to inhibit the lysis of staphylococci treated with bacteriolytic concentrations of penicillin G. Staphylococci injected intraarticularly into the knee joint of rats underwent massive plasmolysis, but structures compatible with cell walls (peptidoglycan) persisted within macrophages in the inflammatory sites, for long periods. It is postulated that the inability of leucocytes to degrade staphylococcal cell-wall components may be the result of the interference, by anionic polyelectrolytes likely to accumulate in the inflammatory sites, with the activation of the autolytic systems. Alternatively, anionic polyelectrolytes may coat the bacterial cells and interfere with the binding of the autolytic enzymes with their corresponding substrates.
Structural basis of myosin motility (1996)

C-209 nicotinamide 1ing ofNADPH. The diphospho b1idge and adenosine portion ofNADPH was clearly bound to those complexes in typical fashion, but the density for the nicotinamide ring was not visible. That portion of the cofactor was disordered but appeared to extended into solvent, being displaced from its normal binding site by the inhibitor. The width ofthe bindin cleft of C. albicans DHFR was significantly larger (1.3-2.0 A) th;n the conesponding dimensions of human DHFR and may be a feature that is exploited by the 5-arylthioquinazoline inhibitors. C. albicans DHFR crystallized in space group P2 1 with two molecules in the asymmetric unit. Final structures had R-factors of 0.155-0.199 at resolution values of 1.6-1.85 A.
Novel Orbital Ordering Induced by Anisotropic Stress in a Manganite Thin Film (2006)

A novel structure of orbital ordering is found in a Nd0.5Sr0.5MnO3 thin film, which exhibits a clear first-order transition, by synchrotron x-ray diffraction measurements. Lattice parameters vary drastically at the metal-insulator transition at 170 K (= T(MI)), and superlattice reflections appear below 140 K (= T(CO)). The electronic structure between T(MI) and T(CO) is identified as A-type antiferromagnetic with a d(x2-y2) ferro-orbital ordering. The new type of antiferro-orbital ordering characterized by the wave vector (1/4 1/4 1/2) in cubic notation emerges below T(CO). The accommodation of the large lattice distortion at the first-order phase transition and the appearance of the novel orbital ordering are brought about by the anisotropy in the substrate, a new parameter for the phase control.
Spatio-Temporal Chirped Amplification for avoiding spectral modifications in ultra-short Petawatt lasers Pulse (2011)

Amplification of large bandwidth pulses in a spatio-temporal configuration is demonstrated at 28 mJ for avoiding spectral shifting in high energy power amplifiers in CPA laser chain. Application to hundreds joules pulses will be discussed.