gebhart/patrepeval huggingface dataset:
Activation of GABA<sub>A</sub> receptors containing the α4 subunit by GABA and pentobarbital (2004)

The activation properties of GABA(A) receptors containing alpha4beta2gamma2 and alpha4beta2delta subunits were examined in the presence of GABA or pentobarbital. The receptors were expressed transiently in HEK 293 cells, and the electrophysiological experiments were carried out using cell-attached single-channel patch clamp or whole-cell macroscopic recordings. The data show that GABA is a stronger activator of alpha4beta2gamma2 receptors than alpha4beta2delta receptors. Single-channel clusters were recorded from alpha4beta2gamma2 receptors in the presence of 10-5000 microm GABA. The maximal intracluster open probability was 0.35, with a half-maximal response elicited by 32 microm GABA. Simultaneous kinetic analysis of single-channel currents obtained at various GABA concentrations yields a channel opening rate constant of 250 s(-1), and a K(D) of 20 microm. In contrast, only isolated openings were observed in the presence of GABA for the alpha4beta2delta receptor. Pentobarbital was a strong activator of both alpha4beta2gamma2 and alpha4beta2delta receptors. The maximal cluster open probability, recorded in the presence of 100 microm pentobarbital, was 0.7. At higher pentobarbital concentrations, the cluster open probability was reduced, probably due to channel block. The results from single-channel experiments were confirmed by macroscopic recordings from HEK cells in the presence of GABA or pentobarbital.
Over-expression of sucrose phosphate synthase in Arabidopsis thaliana results in increased foliar sucrose/starch ratios and favours decreased foliar carbohydrate accumulation in plants after prolonged growth with CO2 enrichment (1998)

Arabidopsis thaliana ecotype Columbia was transformed with a maize sucrose phosphate synthase (SPS) cDNA under the control of the promoter for the small subunit of ribulose-1,5-bisphosphate carboxylase from tobacco (rbcS). The effects of SPS over-expression were compared in plants of the T2 and T3 generations grown either in air or with CO2 enrichment (700 μl l−1) for either 4 or 10 weeks. Maximal extractable foliar SPS activities were three times those of the untransformed controls in the highest rbcS-SPS expressing line. In untransformed Arabidopsis leaves SPS activity was not subject to light/dark regulation, but was modified by incubation with either the inhibitor, orthophosphate, or the activator, mannose. Photosynthesis (Amax) values were similar in all lines grown in air. After 10 weeks of CO2 enrichment a decrease in Amax in the untransformed controls, but not in the high SPS expressors, was observed. There was a strong correlation between the sucrose-tostarch ratio of the leaves and their SPS activity in both growth conditions. The total foliar carbohydrate contents of 4-week-old plants was similar in all lines whether plants were grown in air or with CO2 enrichment. After 10 weeks growth the leaves of the high rbcS-SPS expressors accumulated much less total carbohydrate than untransformed control leaves in both growth conditions. It was concluded that SPS overexpression causes increased foliar sucrose/starch ratios in Arabidopsis leaves and favours decreased foliar carbohydrate contents when plants are grown for long periods with CO2 enrichment.
Wind Turbine Fault Detection Using a Denoising Autoencoder With Temporal Information (2017)

Data-driven approaches have gained increasing interests in the fault detection of wind turbines (WTs) due to the difficulty in system modeling and the availability of sensor data. However, the nonlinearity of WTs, uncertainty of disturbances and measurement noise, and temporal dependence in time-series data still pose grand challenges to effective fault detection. To this end, this paper proposes a new fault detector based on a recently developed unsupervised learning method, denoising autoencoder (DAE), which offers the learning of robust nonlinear representations from data against noise and input fluctuation. A DAE is used to build a robust multivariate reconstruction model on raw time-series data from multiple sensors, and then, the reconstruction error of the DAE trained with normal data is analyzed for fault detection. In addition, we apply the sliding-window technique to consider temporal information inherent in time-series data by including the current and past information within a small time window. A key advantage of the proposed approach is the ability to capture the nonlinear correlations among multiple sensor variables and the temporal dependence of each sensor variable simultaneously, which significantly enhanced the fault detection performance. Simulated data from a generic WT benchmark and field supervisory control and data acquisition data from a real wind farm are used to evaluate the proposed approach. The results of two case studies demonstrate the effectiveness and advantages of our proposed approach.
A template-based approach to XML parsing in C++ (2003)

Add XML support to your project with the Apache Software Foundation's Xerces parser and some C++ code.
Transmission type color filter incorporating a silver film based etalon (2010)

Transmission type color filters based on a thin film Ag-SiO(2)-Ag etalon were built on a quartz substrate, enabling the infrared suppressed transmission and large effective area. They were designed by taking into account the influence of the dispersion characteristics and the thickness of the silver metal. Three different color filters were devised: The cavity length for the red, green and blue filter was 160 nm, 130 nm, and 100 nm respectively, while the metal layer was fixed at 25 nm. The observed spectral pass band was centered at 650 nm, 555 nm, and 480 nm for the red, green, and blue device; the corresponding bandwidth was about 120 nm, 100 nm, and 120 nm; and the peak transmission was all ~60%. For the oblique light incidence the angular dependence of the peak relative transmission was measured to be approximately 1%/degree. The spectral response of the device was also analyzed for two different polarizations as the tilt angle varied up to 12(o), and it was found to be hardly polarization dependent. Finally, as for the positional dependence the relative transmission and the center wavelength were found to vary within 10% and 5 nm respectively over an effective area of 4x4 cm(2).
[Hospital and environment: waste disposal]. (2003)

Like all production units, hospitals produce waste and are responsible for waste disposal. Hospital waste is particular due to the environmental risks involved, particularly concerning infection, effluents, and radionucleide contamination. Management plans are required to meet environmental, hygiene and regulatory obligations and to define reference waste products. The first step is to optimize waste sorting, with proper definition of the different categories, adequate containers (collection stations, color-coded sacks), waste circuits, intermediate then central storage areas, and finally transfer to an incineration unit. Volume and delay to elimination must be carefully controlled. Elimination of drugs and related products is a second aspect: packaging, perfusion pouches, tubing, radiopharmaceutic agents. These later products are managed with non-sealed sources whose elimination depends on the radioactive period, requiring selective sorting and specific holding areas while radioactivity declines. Elimination of urine and excreta containing anti-cancer drugs or intravesical drugs, particularly coming from protected rooms using radioactive iodine is another aspect. There is also a marginal flow of unused or expired drugs. For a health establishment, elimination of drugs is not included as part of waste disposal. This requires establishing a specific circuit with selective sorting and carefully applied safety regulations. Market orders for collecting and handling hospital wastes must be implemented in compliance with the rules of Public Health Tenders.
Effect of Sinecatechins on HPV-Activated Cell Growth and Induction of Apoptosis. (2012)

Sinecatechins demonstrated growth inhibitory potential in all four human papillomavirus-infected tumor cell lines, which may be attributed to the induction of apoptosis, mediated by cell cycle deregulation. In addition, this antiproliferative effect may contribute to the overall cancer-preventative function and possible direct antiviral activity of sinecatechins that may contribute to external genital and perianal warts clearance.
Assessment of dust explosions in the sugar industry with regard to screening technology (2017)

The prevention of dust explosions is a necessary treatment to ensure the safe operation of sugar plants worldwide. Especially in the field of screening technology only few mistakes can lead to hazardous process conditions. This paper discusses the principles of sugar dust explosions with special focus on their formation. An example is given to show possible threats which can occur during production. Advices for choosing suitable process parameters and equipment are given. A professional dust control is key to decrease the risk of dust explosions.
An Image Processing Based Visual Compensation System for Vision Defects (2009)

This paper is dedicated to develop an integrated portable aiding system for the visually impaired, such as color blindness, low vision, or visual field defects. First, individual visual model, including the effective visual field, color response, and contrast sensitivity, for each user can be evaluated by the proposed test method first. Then the input video sequence can be adjusted accordingly to fit each user's visual model hence to compensate their perceptual defects. In combination with head mounted micro displays, it is shown that the proposed visual auxiliary system can improve their visual awareness of the surroundings and enhance their visual perception effectively.
Improving Accuracy for 3D RFID Localization (2012)

Radio Frequency Identification (RFID) becomes a prevalent labeling and localizing technique in the recent years. Deploying indoor RFID localization systems facilitates many applications. Previous approaches, however, are most based on 2D design and cannot provide 3D location information. The lack of one-dimensional information may lead 2D-based systems to inaccurate localization. In this paper, we develop an indoor 3D RFID localization system based on active tag array. In particular, we employ the geometric mean to filter the explicit 3D location information with high accuracy. The experimental results show that our system is efficient in tracking objects and improving the localization accuracy.
Ribonucleic acids in different tea fungus beverages (2003)

In human nutrition, nucleic acids have to be balanced and limited up to 2 g/day because purines are degraded to urate, and excessive production of urate is a cause of gout which primarily affects adult males. Tea fungus beverage is a well known drink with high nutritional value and certain curative effects. Its benefits have been proved in a number of studies but it is still necessary to examine some potential harmful effects of this beverage. The aim of this paper was to investigate content of ribonucleic acids (RNA) produced during tea fungus fermentation on a usual substrate sweetened black tea, and on Jerusalem artichoke tubers (J.A.T) extract using method by Munro and Fleck (1966). pH, ribonucleic acids and also the production of proteins that affect purity of nucleic acids preparations were monitored. A higher value of RNA has been noticed in J.A.T. beverage (0.57 mg/ml) and with observation of usual daily dose of the beverage it is completely safe and useful one.
Spatial spectrum of a general family of self-similar arrays (1987)

We describe the structure factors of a fairly general family of self-similar deterministic arrays (fractals). These are constructed recursively by an inflation method which imitates real physical processes where large clusters are grown from smaller entities. An algebraic approach is used to describe the behavior of the structure factors in the limit of arbitrarily large objects. These structure factors exhibit several scaling properties which reflect the self-similarity of the direct space arrays.
Introspective analysis (2014)

Context-sensitivity is the primary approach for adding more precision to a points-to analysis, while hopefully also maintaining scalability. An oft-reported problem with context-sensitive analyses, however, is that they are bi-modal: either the analysis is precise enough that it manipulates only manageable sets of data, and thus scales impressively well, or the analysis gets quickly derailed at the first sign of imprecision and becomes orders-of-magnitude more expensive than would be expected given the program's size. There is currently no approach that makes precise context-sensitive analyses (of any flavor: call-site-, object-, or type-sensitive) scale across the board at a level comparable to that of a context-insensitive analysis. To address this issue, we propose introspective analysis: a technique for uniformly scaling context-sensitive analysis by eliminating its performance-detrimental behavior, at a small precision expense. Introspective analysis consists of a common adaptivity pattern: first perform a context-insensitive analysis, then use the results to selectively refine (i.e., analyze context-sensitively) program elements that will not cause explosion in the running time or space. The technical challenge is to appropriately identify such program elements. We show that a simple but principled approach can be remarkably effective, achieving scalability (often with dramatic speedup) for benchmarks previously completely out-of-reach for deep context-sensitive analyses.
Mapping the Membrane Topology and Extracellular Ligand Binding Domains of the Retinol Binding Protein Receptor (2008)

STRA6 is a multitransmembrane domain protein not homologous to any other proteins with known function. It functions as the high-affinity receptor for plasma retinol binding protein (RBP) and mediates cellular uptake of vitamin A from the vitamin A-RBP complex. Consistent with the diverse roles of vitamin A and the wide tissue expression pattern of STRA6, mutations in STRA6 are associated with severe pathological phenotypes in humans. The structural basis for STRA6's biochemical function is unknown. Although computer programs predict 11 transmembrane domains for STRA6, its topology has never been studied experimentally. Elucidating the transmembrane topology of STRA6 is critical for understanding its structure and function. By inserting an epitope tag into all possible extracellular and intracellular domains of STRA6, we systematically analyzed the accessibility of each tag on the surface of live cells, the accessibility of each tag in permeabilized cells, and the effect of each tag on RBP binding and STRA6-mediated vitamin A uptake from the vitamin A-RBP complex. In addition, we used a new lysine accessibility technique combining cell-surface biotinylation and tandem-affinity purification to study a region of the protein not revealed by the epitope tagging method. These studies not only revealed STRA6's extracellular, transmembrane, and intracellular domains but also implicated extracellular regions of STRA6 in RBP binding.
Die and let live: leaf senescence contributes to plant survival under drought stress (2004)

Leaf senescence is a highly regulated physiological process that leads to leaf death and is, as such, the last developmental stage of the leaf. Plant aging and environmental stresses may induce the process of senescence. Here we will focus on the role of leaf senescence in field-grown plants as a response to adverse climatic conditions and, more specifically, on how it contributes to plant survival under drought stress. Drought induces several responses in plants including leaf senescence, which plays a major role in the survival of several species. Drought-induced leaf senescence contributes to nutrient remobilisation during stress, thus allowing the rest of the plant (i.e. the youngest leaves, fruits or flowers) to benefit from the nutrients accumulated during the life span of the leaf. In addition, drought-induced leaf senescence, especially when accompanied by leaf abscission, avoids large losses through transpiration, thus contributing to the maintenance of a favourable water balance of the whole plant. Drought-induced leaf senescence occurs gradually and is characterised by specific macroscopic, cellular, biochemical and molecular changes. Leaf yellowing (i.e. chlorophyll degradation) and specific changes in cell ultrastructure (e.g. chromatin condensation, thylakoid swelling, plastoglobuli accumulation), metabolism (e.g.protein degradation, lipid peroxidation) and gene expression occur during leaf senescence in drought-stressed plants. Cytokinins and ABA have been shown to be involved in the regulation of drought-induced leaf senescence, although the possible role of other plant hormones should not be excluded. Reactive oxygen species, whose concentrations increase during drought-induced leaf senescence, are also known to be regulators of this process. The complex mechanisms of regulation of leaf senescence in drought-stressed plants are discussed, and attention is drawn to those aspects that still require investigation.
INFLUENCE OF SOME MINERAL NUTRIENTS FOR CHILLING TOLERANCE ON CUCUMBER SEEDLINGS UNDER PROTECTED CULTIVATION CONDITION (1999)

ISHS International Symposium Greenhouse Management for Better Yield & Quality in Mild Winter Climates INFLUENCE OF SOME MINERAL NUTRIENTS FOR CHILLING TOLERANCE ON CUCUMBER SEEDLINGS UNDER PROTECTED CULTIVATION CONDITION
The altered tumoricidal capacity of macrophages isolated from tumor-bearing mice is related to reduce expression of the inducible nitric oxide synthase gene. (1996)

Nitric oxide (NO) is a major effector molecule in the destruction of tumor cells by activated macrophages. However, in many cases, developing neoplasms appear to be capable of impairing steps in the complex process leading to NO production as a means of avoiding immune destruction. After activation with lipopolysaccharide (LPS), peritoneal-elicited macrophages (PEM) from mice bearing mammary tumors display alterations in their ability to lyse tumor cells due to reduced production of NO. In contrast, when these same cells are stimulated with LPS in combination with interferon gamma (IFN-gamma), they are able to produce NO and lyse targets at normal levels. Since tumor-associated macrophages are intimately associated with the cells of the developing tumor, their ability to produce NO and lyse tumor targets is likely to be more relevant to controlling tumor growth. This population of macrophages exhibited a more profound inability to produce NO and lyse targets and, unlike the PEM, was not able to upregulate these functions even when treated with combinations of LPS and IFN-gamma. Northern and Western blots revealed that inducible nitric oxide synthase (iNOS) mRNA and protein levels correlated directly with the ability of each macrophage population to produce NO, and the levels of these macromolecules were altered sufficiently in tumor bearers' macrophages to account for the diminished NO production described. These results indicate that a spatial gradient of suppression of macrophage cytolytic activity and iNOS expression exists in mammary tumor-bearing mice, whereby macrophages from within the tumor exhibit a more pronounced suppression than the more distally located PEM. This suppression may be due to proximity of the macrophages to the developing tumor, macrophage maturational state, or both.
Pavement Surface Macrotexture Measurement and Applications (2003)

Different techniques for measuring pavement surface macrotexture and their application in pavement management are discussed. The main applications of surface macrotexture are to measure the frictional properties of the pavement surface and to detect hot-mix asphalt (HMA) construction segregation or nonuniformity. Since surface macro-texture can be measured quite efficiently using noncontact technologies and provides important information regarding pavement safety and HMA construction quality, this parameter may be included in the quality assurance or control procedures. Correlations between different measuring devices were investigated utilizing different HMA wearing surfaces. Excellent correlation was found between the circular track meter and sand patch measurements. In addition, the macrotexture determined using a laser profiler correlates well with that determined with sand patch measurements. Consistent with previous studies, it was found that the skid number gradient with speed is inversely proportional to the pavement macrotexture. However, there was a noticeable difference in speed dependency when smooth and ribbed tires were used. Oscillations in the percent normalized gradient with time due to seasonal variations were also observed. Macrotexture measurements hold great promise as tools to detect and quantify segregation for quality assurance purposes. A standard construction specification was proposed in a recent NCHRP study. However, the equation proposed for computing the nonsegregated estimated (mean) texture depth could not be applied to the mixes studied. An alternative equation has been proposed, which estimates the surface macrotexture using the mix nominal maximum size and voids in the mineral aggregate. The study was based on the mixes used at the Virginia Smart Road. Further investigation using other mixes is recommended.
Ozone Degradation of Ink Jet Photoquality Images (2004)

Digital images can now be printed using a range of printer technologies. These include thermal transfer (D2T2), electrophotography, and ink jet, all of which are capable of producing photographic-like prints. There has been much interest in the environmental stability of digital images created by the different printer technologies as the overall picture quality comes closer to that of traditional silver halide photographs. The durability properties of images from a range of desktop ink jet printers have been investigated and a comparison of dye and pigment-based ink systems has also been undertaken. Some of the factors that influence the image stability of photographic-like prints produced by ink jet printers are considered. This paper reports on the influence of gas fading or ozone stability of digital images printed onto ink jet photopapers. In particular the stability of dye based inks on microporous media has been investigated. The major influences on the image properties are discussed and the importance of the ink/media interactions are considered. The environment of the colorant was found to have a significant influence on the durability of the image. Much of the research activity in ink jet has focused on attempting to solve durability issues in order to bridge the gap with silver halide photographic images.
A perceptual metric for production testing (2004)

This paper describes a perceptually-based image comparison process that can be used to tell when images are perceptually identical even though they contain some numerical differences. The technique has shown much utility in the production testing of rendering software.