gebhart/patrepeval huggingface dataset:
Feasibility of using saltcedar as a filler in injection-molded polyethylene composites (2009)

Saltcedar (Tamarix ramosissima) was investigated for use as a filler in wood-plastic composites (WPCs).The mineral content, water-soluble extractive content, and thermal stability of saltcedar flour were compared with those of a commercial pine wood flour.The wood flours were compounded with plastic, and the viscosities of the composite melts containing the two species were compared.Injectionmolded composites produced from the compounded material were evaluated for mechanical performance and weatherability.Saltcedar flour had more minerals and water-soluble extractives than pine flour, which resulted in lower thermal stability, but also lower melt viscosity when compounded with high-density polyethylene.Injection-molded WPCs made from unextracted saltcedar performed similarly to those made from pine in accelerated weathering tests, but their mechanical properties were generally lower.The flexural modulus of elasticity increased when extracted wood flour was used, especially for the saltcedar composites.However, color stability and flexural strength changed little.Producing WPCs from these composites is possible, although economically feasible applications that use the advantageous properties of these species and that can tolerate or address the less desirable ones need to be identified and demonstrated.
COX-2, Cell Proliferation and PMA in Head-and-Neck Cancer Cells (2009)

Phorbol 12-myristate 13-acetate (PMA) affects a variety of cell processes, including proliferation and differentiation. In most normal cell types, PMA enhances proliferation by a protein kinase C (PKC)- dependent mechanism, while the proliferation of cancer cell lines is inhibited by PMA. PMA has been shown to induce cyclooxygenase-2 (COX-2) production in many cell lines. We examined the effect of PMA on functions of induced COX-2 on proliferation of head-and-neck UMSCC-22B cancer cells. PMA was found to inhibit head-and-neck cancer cell proliferation in a cell viability assay and to induce apoptosis. Abundance of p21 protein and p53 in these cells was increased by PMA treatment. The phorbol ester increased p21 expression in 22B cells through the classical PKC pathway and independently of activation of p53. In addition, PMA increased expression of COX-2 in a time-dependent, PKC-requiring manner. COX-2 siRNA increased abundance of both p53 and p21 in 22B cells and importantly potentiated the anti-proliferative effect of PMA. Confocal microscopy revealed that PMA increased nuclear accumulation of COX-2, but not COX-1, and that COX-2 formed complexes with p53, p21 and the coactivator, p300. Chromatin immunoprecipitation showed that nuclear fraction COX-2 and p53 bound to the promoter region of p21. PMA did not significantly increase PGE2 levels in cultured medium of 22B cells, but did increase by 13-fold the levels of PGE2 in the medium of immortalized normal (293T) cells. In conclusion, our results show that PMA inhibits cell proliferation in head-and-neck cancer cells by a mechanism that is potentiated by COX-2 siRNA. The latter results in an increase of p53 and p21 in PMA-treated cancer cells. In the absence of its siRNA, COX-2 is increased in PMAexposed cancer cells and becomes a nucleoprotein, where it complexes with p53 and p21. Thus, the antiproliferative activity of PMA in 22B cells is moderated by concurrent induction by PMA of COX-2 accumulation; this moderation may be due to reduction by COX-2 of availability of p21 and p53 in the nucleus. Keywords: Phorbol ester, protein kinase C, p53, p21, cyclooxygenases, head and neck cancer cells
A goat mortality study in the southern North Island (1988)

A study was undertaken to indicate the importance of different causes of death in goats and to investigate the management factors which influence these problems. Over a 15 month period, 324 dead goats were received from 67 farms in the Horowhenua, Wairarapa, Wanganui and Wellington regions. Although a wide range of diseases was encountered in the study, the major causes of mortality could be divided into 4 groups: problems directly related to management, microbial diseases, nematode parasitism, and trace element related deficiencies and toxicities. The highest proportion of deaths related directly to management problems and included deaths from hypothermia, mismothering, premature birth, ruminal acidosis, pregnancy toxaemia, trauma, and plant and chemical toxicities. In larger flocks, microbial diseases including Pasteurella pneumonia and yersiniosis were major problems. Deaths from nematode parasitism were predominantly observed in goats 12 months of age and older. White muscle disease (selenium/vitamin E deficiency) was the major trace element deficiency causing death in goats. The influence of factors including age of goat, flock size and management practices on the major causes of death are discussed.
Feasibility study of ultrasonic/sonic flowmeters for coal slurries (1976)

An analysis of sonic techniques for flow measurement in coal slurries shows that operation of a transmission type flowmeter is feasible for a range of one meter at a frequency range of 32.5 kHz to 400 kHz and a range of ten centimeters at a frequency range of 325 kHz to 1 MHz using the sonar equation as the measure of performance. Slurries with moderate concentrations of 10 to 30 percent solids by volume and particle size of 100 microns are assumed. Based on this assumption, the attenuation constant, the transmission loss, the directional gain, the source level and the processing gain for the transmission type flowmeter are determined.
Aktiver Sauerstoff auf einem Au/TiO<sub>2</sub>‐Katalysator – Bildung, Stabilität und Aktivität für die CO‐Oxidation (2011)

In bester Lage: Aktiver Sauerstoff für die CO-Oxidation über Au/TiO2-Katalysatoren ist eine sehr stabile Sauerstoffspezies, deren Bildung leicht und kaum aktiviert ist. Es handelt sich dabei um Oberflächengittersauerstoff am Rand der Au-TiO2-Grenzfläche, der durch die Au-Nanopartikel aktiviert ist. Bei höheren Temperaturen können wegen thermisch aktivierter Oberflächendiffusion von OGitter und Leerstellen auch weiter entfernte Spezies an der Reaktion teilnehmen.
Purification and Characterization of Three Chitosanase Activities from <i>Bacillus megaterium</i> P1 (1990)

Bacillus megaterium P1, a bacterial strain capable of hydrolyzing chitosan, was isolated from soil samples. Chitosan-degrading activity was induced by chitosan but not by its constituent d-glucosamine. Extracellular secretion of chitosanase reached levels corresponding to 1 U/ml under optimal conditions. Three chitosan-degrading proteins (chitosanases A, B, and C) were purified to homogeneity. Chitosanase A (43 kilodaltons) was highly specific for chitosan and represented the major chitosan-hydrolyzing species. Chitosanases B (39.5 kilodaltons) and C (22 kilodaltons) corresponded to minor activities and possessed comparable specific activities toward chitosan, chitin, and cellulose. Chitosanase A was active from pH 4.5 to 6.5 and was stable on the basis of activity up to 45 degrees C. The optimum temperature for enzymatic chitosan hydrolysis was 50 degrees C. Kinetic studies on chitosanase A suggest that the enzyme is substrate inhibited. The apparent K(m) and V(max) determined at 22 degrees C and pH 5.6 were 0.8 mg/ml and 280 U/mg, respectively. End products of chitosan hydrolysis by each of the three chitosanases were identified as glucosamine oligomers, similar to those obtained for previously reported chitosanase digestions.
Assessment of penile erection methods in rhesus macaques to model pharmacokinetics of antiretroviral drugs and penile infection with simian immunodeficiency virus (2016)

Rectal electrostimulation treatment elicits transient but consistent penile erections in macaques. High rigidity following RES treatment demonstrates increased blood flow and may provide a functional model for penile PK evaluations and possibly simian immunodeficiency virus (SIV) transmission under erect conditions.
Novel immunoglobulin binding proteins (1992)

Conference Article| August 01 1992 Novel immunoglobulin binding proteins MICHAEL G. GORE; MICHAEL G. GORE 1Department of Biochemistry, SERC Centre for Molecular Recognition, School of Biological Sciences, Bassett Crescent East, University of Southampton, Southampton, SO9 3TU Search for other works by this author on: This Site PubMed Google Scholar ANDREW G. POPPLEWELL; ANDREW G. POPPLEWELL 1Department of Biochemistry, SERC Centre for Molecular Recognition, School of Biological Sciences, Bassett Crescent East, University of Southampton, Southampton, SO9 3TU Search for other works by this author on: This Site PubMed Google Scholar WILLIAM F. FERRIS; WILLIAM F. FERRIS 1Department of Biochemistry, SERC Centre for Molecular Recognition, School of Biological Sciences, Bassett Crescent East, University of Southampton, Southampton, SO9 3TU Search for other works by this author on: This Site PubMed Google Scholar MICHAEL SCAWEN; MICHAEL SCAWEN +PHLS, Centre for Applied Microbiology and Research, Porton, Salisbury, Wiltshire, SP4 OJG. Search for other works by this author on: This Site PubMed Google Scholar TONY ATKINSON TONY ATKINSON 1Department of Biochemistry, SERC Centre for Molecular Recognition, School of Biological Sciences, Bassett Crescent East, University of Southampton, Southampton, SO9 3TU Search for other works by this author on: This Site PubMed Google Scholar Biochem Soc Trans (1992) 20 (3): 289S. https://doi.org/10.1042/bst020289s Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn MailTo Cite Icon Cite Get Permissions Citation MICHAEL G. GORE, ANDREW G. POPPLEWELL, WILLIAM F. FERRIS, MICHAEL SCAWEN, TONY ATKINSON; Novel immunoglobulin binding proteins. Biochem Soc Trans 1 August 1992; 20 (3): 289S. doi: https://doi.org/10.1042/bst020289s Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsBiochemical Society Transactions Search Advanced Search This content is only available as a PDF. © 1992 Biochemical Society1992 Article PDF first page preview Close Modal You do not currently have access to this content.
Down-Regulation of Sprouty2 in Non–Small Cell Lung Cancer Contributes to Tumor Malignancy via Extracellular Signal-Regulated Kinase Pathway-Dependent and -Independent Mechanisms (2007)

Sprouty (Spry) proteins function as inhibitors of receptor tyrosine kinase signaling mainly by interfering with the Ras/Raf/mitogen-activated protein kinase cascade, a pathway known to be frequently deregulated in human non-small cell lung cancer (NSCLC). In this study, we show a consistently lowered Spry2 expression in NSCLC when compared with the corresponding normal lung epithelium. Based on these findings, we investigated the influence of Spry2 expression on the malignant phenotype of NSCLC cells. Ectopic expression of Spry2 antagonized mitogen-activated protein kinase activity and inhibited cell migration in cell lines homozygous for K-Ras wild type, whereas in NSCLC cells expressing mutated K-Ras, Spry2 failed to diminish extracellular signal-regulated kinase (ERK) phosphorylation. Nonetheless, Spry2 significantly reduced cell proliferation in all investigated cell lines and blocked tumor formation in mice. Accordingly, a Spry2 mutant unable to inhibit ERK phosphorylation reduced cell proliferation significantly but less pronounced compared with the wild-type protein. Therefore, we conclude that Spry2 interferes with ERK phosphorylation and another yet unidentified pathway. Our results suggest that Spry2 plays a role as tumor suppressor in NSCLC by antagonizing receptor tyrosine kinase-induced signaling at different levels, indicating feasibility for the usage of Spry in targeted gene therapy of NSCLC.
Synthesis of Nucleoside Di- and Triphosphates and Dinucleoside Polyphosphates with <i>cyclo</i>Sal-Nucleotides (2009)

A new and efficient method for the synthesis of nucleoside di- and triphosphates as well as dinucleoside polyphosphates (Np(n)N') is described. 5-Acceptor-substituted (5-nitro and 5-chloro) cycloSal-nucleotides are used as starting material that were reacted with a variety of phosphate nucleophiles as pyrophosphate or nucleotides to the corresponding products in short times and very good yields. After consumption of the starting cycloSal-phosphate triester, first the protecting groups were cleaved and finally the products were isolated after RP-column chromatography. Examples are shown for all five pyrimidine and purine bases found in natural nucleosides as well as one non-natural pyrimidine base to prove that the method can be applied generally.
CNFET-Based High Throughput SIMD Architecture (2017)

Carbon nanotube field effect transistor (CNFET), using the carbon nanotubes (CNTs) as the material for conducting, is a promising alternative of CMOS technology to overcome the “power wall” issue. Recently, a microprocessor solely based on CNFETs was fabricated and demonstrated, which is a big step forward to the industrial practice. However, CNFETs are inherently subject to much larger process variation or manufacturing defects; thereby it may cause significant design cost to build high performance processors. This is exacerbated in the large register file (RF) architectures widely used in single instruction multiple data (SIMD) architectures, e.g., general public utilities style processors, where the number of critical paths are multiplied by the SIMD width and thread count. In this paper, we seek cost-effective approaches to address the issues by judiciously exploiting the strong asymmetric spatial correlation in the variation unique to the CNFET fabrication process. This paper presents a microarchitectural model to characterize CNFET delay variation and malfunction, under which we show that the RF organizations coupled with the architectural schemes are critical to the performance and power consumption of the SIMD processor. Therefore, we propose several architectural techniques to mitigate the performance degradation and the impact of CNT metallization, leveraging the distinctive CNFET characteristics and the unique features in the SIMD processors. Experimental results verify the effectiveness of the proposed techniques and demonstrate the great opportunity offered by this new device technology.
Synthesis of 1-phosphacycloalkene phosphorus-metal(CO)5 complexes (M = Cr, W) by intramolecular phospha-Wittig reactions (1991)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSynthesis of 1-phosphacycloalkene phosphorus-metal(CO)5 complexes (M = Cr, W) by intramolecular phospha-Wittig reactionsAngela Marinetti, Pascal Le Floch, and Francois MatheyCite this: Organometallics 1991, 10, 4, 1190–1195Publication Date (Print):April 1, 1991Publication History Published online1 May 2002Published inissue 1 April 1991https://pubs.acs.org/doi/10.1021/om00050a061https://doi.org/10.1021/om00050a061research-articleACS PublicationsRequest reuse permissionsArticle Views105Altmetric-Citations17LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Stable Carbonium Ions. XXIX.<sup>1</sup> The Reaction of Alkyl (Acyl) Sulfinylamines and Isocyanates (Thioisocyanates) with Nitrosonium Salts. New Deaminative Formations of Carbonium (Oxocarbonium) Ions (1966)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTStable Carbonium Ions. XXIX.1 The Reaction of Alkyl (Acyl) Sulfinylamines and Isocyanates (Thioisocyanates) with Nitrosonium Salts. New Deaminative Formations of Carbonium (Oxocarbonium) IonsGeorge A. Olah, Norman Friedman, J. Martin Bollinger, and Joachim LukasCite this: J. Am. Chem. Soc. 1966, 88, 22, 5328–5330Publication Date (Print):November 1, 1966Publication History Published online1 May 2002Published inissue 1 November 1966https://pubs.acs.org/doi/10.1021/ja00974a057https://doi.org/10.1021/ja00974a057research-articleACS PublicationsRequest reuse permissionsArticle Views226Altmetric-Citations29LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Development of a portable underwater light (1972)

This paper discusses the development of a unique portable underwater light which is rugged, shock-resistant, and is suitable for continuous use in air or underwater. The light is designed for general area illumination either underwater or on the surface. The light assembly consists of a 10,000 lumen tungsten-halogen lamp, a heat treated globe, a heat-sinked fixture, and a cable reel with appropriate electrical connections. When operated in air the fixture stabilizes at a temperature of approximately 850 degrees F, and it may be immersed in cold water while in operation without damage. The fixture will withstand static pressure in excess of 2000 PSI.
How to avoid excitation of parasitic modes in MW-class gyrotrons? (2008)

Megawatt-class, millimeter-wave gyrotrons for plasma heating in controlled fusion reactors operate either in very long pulses or in continuous-wave regimes. Therefore, to handle ohmic losses of microwave power in the cavity walls, these gyrotrons are designed for operation at high-order modes with a very dense frequency spectrum. In such conditions, to provide excitation of the desired mode and then its high-efficiency operation, it is necessary to carefully analyze the gyrotron start-up scenario. All gyrotrons operate either with diode or triode-type magnetron electron guns. Although it is simpler for users to operate with gyrotrons having diode-type guns, in such gyrotrons the excitation of a lower frequency parasitic mode prior to excitation of the desired mode is practically unavoidable. Therefore, even when the desired mode is excited later, when the beam voltage approaches its nominal value, there is a time interval during which the gyrotron generates MW-level radiation of the parasitic mode which can destroy many plasma diagnostics tools in tokamaks and stellarators. Our simulations show that when the voltage rise is short enough this excitation of parasitic modes can be avoided. It is also shown that in gyrotrons with triode-type electron guns it is even much simpler to avoid this parasitic mode excitation. To do this one can use one high-voltage supply with a slowly growing beam voltage but utilize for the mod-anode, which can be treated as a currentless electrode, another supply providing fast voltage rise.
Declines in Birth Weight and Fetal Growth Independent of Gestational Length (2013)

I.
ChemInform Abstract: Heterocyclic β‐Enamino Esters. Part 39. Synthesis of <sup>1</sup>H‐Pyrazolo[3,4‐d]pyrimidines. (1986)

Abstract Die Ester (I) sowie die daraus zugänglichen Hydrazide (VI) dienen als Ausgangsverbindungen für die Darstellung der Titelverbindungen (V), (VIII), (IX), (XI) und (XIV).
Utilization of open-source high availability middleware in next generation telecom services (2009)

High availability is a renowned property of telecom systems. It is the ability to provide continuous and uninterrupted service regardless of hardware or software failures. Implementation of such property comes at great price in terms of time consumption and expenses. Nowadays such expensive practice is no longer acceptable and thus, we explored a possibility of using an open-source high availability solution for building of next generation telecom service. In this paper, we present a prototype system built using an open-source high availability solution, discuss the challenges we addressed and show relevant performance and availability characteristics.
Birds Of The Guadalupe Mountain Region Of Western Texas (1940)

Rising from the desert floor amid Mesquite, cactus, and Grease Bush, Guadalupe Peak has the distinction of being the highest point in the big state of Texas -reaching an altitude of 8758 feet above sea level. There, among its high ridges and escarpments in the heart of a Texas desert plain, one finds a beautiful Canadian Transition Zone forest. Dense stands of conifers -Western Yellow Pine and Douglas Fir -along with oaks and maples, combine to make the area a biotic community quite unlike the remainder of Texas.
Iterative Threshold Decoding Without Interleaving (2003)

In this paper, a novel iterative error control technique based on the threshold decoding algorithm and new convolutional self-doubly orthogonal codes is proposed. It differs from parallel concatenated Turbo decoding as it uses a single convolutional en- coder, a single decoder and hence no interleaver, neither at the en- coding nor at the decoding. Decoding is performed iteratively using a single threshold decoder at each iteration thereby providing good tradeoff between complexity, latency and error performance.
Effects of 1‐Methyl‐3‐propyl‐7‐butylxanthine (MPBX) on Idarubicin‐induced Antitumor Activity and Bone Marrow Suppression (2000)

The effects of 1-methyl-3-propyl-7-butylxanthine (MPBX), a xanthine derivative, on idarubicin (IDA)-induced antitumor activity against P388 leukemia cells (P388) and bone marrow suppression were examined. In P388 tumor-bearing mice, the combination of MPBX with IDA increased the antitumor activity of IDA. The IDA concentration in the tumors in the MPBX combination group increased by 2.0-fold compared to the level in the IDA-alone group. On the other hand, as regards IDA-induced bone marrow suppression, the combination of MPBX with IDA reduced the decrease in the bone marrow cell number by 30% compared to that in the IDA-alone group. In addition, the IDA concentration in the bone marrow cells was decreased by the combination of MPBX with IDA. An in vitro experiment showed that MPBX facilitated IDA influx and suppressed IDA efflux in P388 cells. In conclusion, the combination of MPBX with IDA increased the antitumor activity and decreased the bone marrow suppression. Therefore, we expect that the combination of MPBX with IDA will be useful for leukemia chemotherapy.