gebhart/patrepeval huggingface dataset:
Organic/inorganic hybrid materials : symposium held April 13-17, 1998, San Francisco, California, U.S.A. (1998)

In principle, if one can control processing to achieve the highest homogeneity, then it should be possible to obtain exceptional control of a material's reproducibility, predictability and tailorability. Over the past 30 years, tremendous investments of time, energy and resources have been made to learn to control materials properties at the atomic scale using chemical processing methods. Successes in chemical processing are now being extended to the next length scales (1-1000nm) to produce nanocomposite or organic/inorganic hybrid materials. Recent exceptional advances in hybrid materials synthesis, characterization and processing suggest that this area will occupy scientists and engineers for at least as long a period, and prompted this collection of inter-disciplinary research papers. Topics include: molecular and nanocomposite hybrid synthesis, processing and characterization; porous materials produced by hybrid processing methods; hybrid materials that exhibit optical, electronic, catalytic or physical properties; and new methods of characterizing these materials.
Immune Reconstitution of the CD4 T‐Cell Compartment in HIV Infection (2001)

This chapter reviews the major quantitative, qualitative, and functional characteristics of CD4 T-cell reconstitution together with its limitations and the new insights that recently developed flow cytometry methods have brought to the understanding of such CD4 T-cell reconstitution.
ChemInform Abstract: Synthesis auf Naphthoquinone Antibiotics by Intramolecular Alkyne Cycloaddition to Carbene‐Chromium Complexes. (1986)

Abstract Ausgehend von der intermolekularen Alkin‐ Carben‐Cyclisierung zwischen (I) und (II) lassen sich auf dem beschriebenen Weg die Pyrane (VII) und (VIII) synthetisieren, die nach bekannten Verfahren in Nanaomycin A (IXa) übergeführt werden können.
Highly oriented poly(di‐<i>n</i>‐alkylsilylene) films on oriented PTFE substrates (1993)

Highly oriented polysilylene layers have potential applications in electrophotography, nonlinear optics, display fabrication, and microlithography. The preparation of such layers by crystallization on a highly oriented PTFE substrate is reported, and their assessment by optical birefringence, electron diffraction and dichroic infrared experiments described. Why this orientation technique works is not yet clear, especially as it can be applied to poly(di‐ n ‐alkylsilylen)s with different crystal structures. Several possible underlying mechanisms are discussed.
Specificity of Delayed Cutaneous Hypersensitivity Reactions to Extracts of Human Tumor Cells2 (1978)

The specificity of numerous extracts used for delayed cutaneous hypersensitivity (OCH) testing of cancer patients was evaluated. Tests were performed with crude preparations (hypotonic membrane preparations and 3-M KCI extracts) and with Sephadex and gradient polyacrylamide gel electrophoresis (PAGE) fractions prepared from tumors and from tissue culture (TC) cell lines derived from breast cancer and Ewing's sarcoma. The reactivity and specificity of individual extracts varied considerably. Some extracts were quite reactive and showed diseaserelated specificity; i.e., patients with tumors similar to the extract source were more reactive in OCH testing to some types of extracts than were patients with dissimilar tumors. Other extracts produced skin reactions in patients with various tumors or were poorly reactive. Comparative testing between KCI extracts of cells from the pleural effusion of a Ewing's sarcoma patient and of cells from the TC line derived from these pleural effusion cells showed similar reactivity in patients with Ewing's sarcoma. Of patients tested with KCI extracts of the fresh tumors, 88% were reactive compared with 75% of patients tested with KCI extracts of the tissue-cultured tumor cells; 64% of patients tested simultaneously with KCI extracts of the fresh and tissue-cultured tumors were reactive to both. Sephadex fraction II from a metastatic malignant melanoma elicited many OCH reactions but discriminated poorly between breast cancer and melanoma patients. In contrast, gradient PAGE fractions of a primary breast tumor and of MCF-7 cells, a TC line derived from breast cancer, elicited a breast cancer-related pattern of reactivity. PAGE region 2a of the primary breast tumor and of MCF-7, which gave the best discrimination of all the regions tested, was reactive in 86 and 69% of breast cancer patients, respectively, and in 29 and 28% of patients with other types of neoplasms, respectively. A particularly pure separation of MCF-7 PAGE region 2b1-3 gave positive OCH reactions in 58% of breast cancer patients and in none of 16 patients with cancers of other sites. This study indicated that OCH testing may be useful in the detection of cellmediated immunity to tumor-associated antigens on both fresh tumors and on TC derived from tumors. However, for potential clinical use, a careful examination of the reactivity and specificity of each extract and possibly separation by physicochemical means of tumor-associated antigens from cross-reacting antigens or nonspecific materials seem necessary.
Oxime Coupling of Active Site Inhibited Factor Seven with a Nonvolatile, Water-Soluble Fluorine-18 Labeled Aldehyde (2019)

A nonvolatile fluorine-18 aldehyde prosthetic group was developed from [<sup>18</sup>F]SFB, and used for site-specific labeling of active site inhibited factor VII (FVIIai). FVIIai has a high affinity for tissue factor (TF), a transmembrane protein involved in angiogenesis, proliferation, cell migration, and survival of cancer cells. A hydroxylamine N-glycan modified FVIIai (FVIIai-ONH<sub>2</sub>) was used for oxime coupling with the aldehyde [<sup>18</sup>F]2 under mild and optimized conditions in an isolated RCY of 4.7 ± 0.9%, and a synthesis time of 267 ± 5 min (from EOB). Retained binding and specificity of the resulting [<sup>18</sup>F]FVIIai to TF was shown in vitro. TF-expression imaging capability was evaluated by in vivo PET/CT imaging in a pancreatic human xenograft cancer mouse model. The conjugate showed exceptional stability in plasma (>95% at 4 h) and a binding fraction of 90%. In vivo PET/CT imaging showed a mean tumor uptake of 3.8 ± 0.2% ID/g at 4 h post-injection, a comparable uptake in liver and kidneys, and low uptake in normal tissues. In conclusion, FVIIai was labeled with fluorine-18 at the N-glycan chain without affecting TF binding. In vitro specificity and a good in vivo imaging contrast at 4 h postinjection was demonstrated.
A Program to Limit Donor Exposures to Neonates Undergoing Extracorporeal Membrane Oxygenation (1994)

We conclude that the changes in blood bank component selection and management as well as physician practice were effective in substantially reducing ECMO-related transfusion volumes and the resulting donor exposures.
Classification of modulation modes using time-frequency methods (1999)

This paper proposes a new technique for feature extraction of modulated signals which is based on a pattern recognition approach. The new algorithm uses the cross Margenau-Hill distribution, autoregressive modeling, and amplitude variations to detect phase shifts, frequency shifts, and amplitude shifts, respectively. Our method is capable of classifying PSK2, PSK4, PSK8, PSK16, FSK2, FSK4, QAM8 and OOK signals. Unlike most of the existing decision-theoretic approaches, no explicit a priori information is required by our algorithm. Consequently, the method is suitable for application in a general noncooperative environment. Furthermore, our approach is computationally inexpensive. Simulation results on both synthetic and "real world" short-wave signals show that our approach is robust against noise up to a signal-to-noise ratio (SNR) of approximately 10 dB. A success rate greater than 94 percent is obtained.
Method of Laser‐induced Breakdown Detection and Application Examples (2004)

The Laser‐induced Breakdown Detection is a rather novel and highly sensitive method for the non‐invasive determination of both the concentration and the number‐weighted mean diameter of nanoparticles (colloids) in liquids. Compared to other methods the limit of detection is lower by several orders of magnitude. Their high surface to masse ratio results in a large sorption capacity that on the one hand offers great technical possibilities, on the other hand colloidal transport of pollutants can be a serious environmental problem.
Serum Protein S-100 Predicts Clinical Outcome in Patients with Melanoma Treated with Adjuvant Interferon – Comparison with Tyrosinase RT-PCR (2005)

S-100 > or =0.15 microg/l and a positive RT-PCR during adjuvant interferon therapy indicate a high risk of death in resected melanoma patients. S-100 determination has a higher positive predictive value than RT-PCR, while tyrosinase RT-PCR adds prognostic information in patients with S-100 <0.15 microg/l.
Optimal Pilot and Payload Power Control in Single-Cell Massive MIMO Systems (2016)

This paper considers the jointly optimal pilot and data power allocation in single-cell uplink massive multiple-input-multiple-output systems. Using the spectral efficiency (SE) as performance metric and setting a total energy budget per coherence interval, the power control is formulated as optimization problems for two different objective functions: the weighted minimum SE among the users and the weighted sum SE. A closed form solution for the optimal length of the pilot sequence is derived. The optimal power control policy for the former problem is found by solving a simple equation with a single variable. Utilizing the special structure arising from imperfect channel estimation, a convex reformulation is found to solve the latter problem to global optimality in polynomial time. The gain of the optimal joint power control is theoretically justified, and is proved to be large in the low-SNR regime. Simulation results also show the advantage of optimizing the power control over both pilot and data power, as compared to the cases of using full power and of only optimizing the data powers as done in previous work.
2.6-GHz RF inductive power delivery for contactless on-wafer characterization (2008)

This paper presents the critical components of a contactless IC testing infrastructure to power on-chip characterization circuits. This includes an inductively-coupled, contactless power delivery system implemented on a 90nm CMOS technology using 150μm times 150μm on-chip and off-chip spiral inductors, low loss rectifiers and on-chip voltage regulators to create a constant and repeatable 1-V, 8.5-mW DC source. We present the measured process variation of ring oscillator test circuits in contrast to the on-chip voltage source variation to demonstrate the feasibility of process variation analysis using this system.
FIB∕SEM Structural Analysis Of Through-Silicon-Vias (2011)

Different milling strategies for the structural analysis of through‐silicon‐vias with a dualbeam focused ion beam/scanning electron microscope are discussed. Particular attention is given to methods to reduce the analysis time and to minimize the curtaining artifacts.
GUÍA DE LA CALIDAD PARA EL REGISTRO DE VACUNAS TERAPÉUTICAS CONTRA EL CÁNCER (2007)

<p align="justify"><span style="font-size: x-small; font-family: Times_New_Roman083.313;">El registro de los productos biofarmacéuticos constituye una actividad muy compleja caracterizada por un largo tiempo que puede durar entre 15 y 20 años durante el cual se van acumulando las evidencias a través de estudios, ensayos y documentaciones que avalan lo transcurrido durante la I + D y debe responder a las diferentes exigencias regulatorias que pueden existir o existirán en la agencia, donde se desee registrar el medicamento. Es esta problemática que se aborda y como solución se plantea una guía de calidad para lograr el registro de vacunas terapéuticas contra el cáncer en cualquier mercado del mundo.</span></p>
Regioselective reduction of maleimide and citraconimide derivatives: general preparation of 5-hydroxy-1,5-dihydropyrrol-2-one (2002)

NaBH4 reduction of citraconimide derivatives regioselectively afforded 5-hydroxy-4-methyl-1,5-dihydropyrrol-2-ones, whereas NaBH4–CeCl3 or DIBAL-H reduction gave 5-hydroxy-3-methyl-1,5-dihydropyrrol-2-ones.
Primary Peritoneal Epithelioid Hemangioendothelioma (2006)

Epithelioid hemangioendothelioma is an uncommon malignant vascular tumor of intermediate grade that occurs in a variety of organs and soft tissues. Diagnosis of epithelioid hemangioendothelioma is often complicated by the rarity of the tumor, and because the tumor shares many morphologic features with other peritoneal neoplasms. This report presents 3 cases of epithelioid hemangioendotheliomas arising as primary tumors of the peritoneum and reviews 7 previously reported cases to establish the demographic, clinical, morphologic, immunohistochemical, and ultrastructural features of this neoplasm. These cases demonstrate that the light microscopic features are very similar to epithelioid hemangioendothelioma arising at more conventional sites, such as the liver, that immunohistochemical analysis provides a reliable approach for confirming or establishing the diagnosis, and that at least one endothelial marker (either CD31, CD34, or factor VIII) should be positive for a definitive diagnosis. This series identifies the characteristics of peritoneal epithelioid hemangioendothelioma that can be reliably used for diagnosis.
Emerging paradigms and questions on pro-angiogenic bone marrow-derived myelomonocytic cells (2011)

Cancer-related inflammation has emerged in recent years as a major event contributing to tumor angiogenesis, tumor progression and metastasis formation. Bone marrow-derived and inflammatory cells promote tumor angiogenesis by providing endothelial progenitor cells that differentiate into mature endothelial cells, and by secreting pro-angiogenic factors and remodeling the extracellular matrix to stimulate angiogenesis though paracrine mechanisms. Several bone marrow-derived myelonomocytic cells, including monocytes and macrophages, have been identified and characterized by several laboratories in recent years. While the central role of these cells in promoting tumor angiogenesis, tumor progression and metastasis is nowadays well established, many questions remain open and new ones are emerging. These include the relationship between their phenotype and function, the mechanisms of pro-angiogenic programming, their contribution to resistance to anti-angiogenic treatments and to metastasis and their potential clinical use as biomarkers of angiogenesis and anti-angiogenic therapies. Here, we will review phenotypical and functional aspects of bone marrow-derived myelonomocytic cells and discuss some of the current outstanding questions.
Ethyl Thioglycosides of D-Mannose and D-Galactose and a New Synthesis of Styracitol (1949)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTEthyl Thioglycosides of D-Mannose and D-Galactose and a New Synthesis of StyracitolJosef. Fried and Doris E. WalzCite this: J. Am. Chem. Soc. 1949, 71, 1, 140–143Publication Date (Print):January 1, 1949Publication History Published online1 May 2002Published inissue 1 January 1949https://pubs.acs.org/doi/10.1021/ja01169a038https://doi.org/10.1021/ja01169a038research-articleACS PublicationsRequest reuse permissionsArticle Views325Altmetric-Citations62LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
<title>Structural dynamic health monitoring of adaptive CFRP structures</title> (1999)

The DLR Institute of Structural Mechanics is engaged in the construction and optimization of adaptive structures for aerospace and terrestrial applications. Due to the FFS- Project, one of the recent works of the Institute is the reduction of buffet induced vibration loads at a fin. The construction of modern aircrafts is influenced b the increasing use of fiber composites. They have more specific stiffness and strength properties than metals. On the other hand the layered structure leads to new kinds of damages like delaminations. In the fin interface there are actuators and sensors integrated. Therefore the fin is connected with a controller. For the extension of this adaptive system towards an on-line tool for health monitoring this controller can be used as an identifier of the structure's modal parameters. The most promising procedure is based on MX filters. These filters constitute the filter coefficients from which a fast transformation procedure extracts the modal parameters. The changes of these parameters are related to the location and extent of the damage. So when using the already integrate controller for system identification, one can have a low-cost on-line damage detection for dynamic adaptive structures. First off-line test at CFRP plates have shown the ability to detect delaminations.
Pronounced effect of caprylocaproyl macrogolglycerides on nasal absorption of IS-159, a peptide serotonin 1B/1D-receptor agonist (2000)

2% caprylocaproyl macrogolglyceride markedly increased the absorption of IS-159 through the nasal mucosa and elicited only mild irritant effects.
Convenient Method for the Construction of Quinoline Skeletons from <i>N</i>-Methylarylamines via <i>N</i>-(<i>t</i>-Butyldioxymethyl)arylamines (2002)

Construction of quinoline skeletons can be performed by the ruthenium-catalyzed oxidation of N-methyl-N-alkylanilines with t-butyl hydroperoxide followed by treatment with olefins in the presence of titanium tetrachloride.
Hereditary muscular hypertrophy in cattle is associated with a reduced myocardial contractility (1994)

info:eu-repo/semantics/published
Effect of Chemical Oxidation on the Self-Assembly of Organometallic Block Copolymers (2005)

The thermodynamic interactions in poly(styrene-block-ferrocenyldimethylsilane) and poly(isoprene-block-ferrocenyldimethylsilane) copolymers were systematically tuned by oxidation of the ferrocene moieties with silver nitrate. Small-angle X-ray scattering experiments show that oxidizing 8% of the ferrocene moieties lowers the order-disorder transition temperature of the copolymers by as much as 40 degrees C.
The Right Approach to Right of Way Engineering (2016)

Many steps are necessary to prepare the proper documents for right of way engineering. In this session we will discuss the steps and procedures required to be in compliance with INDOT statutes, including LRS electronic submittals.
Is It Science Yet?: Intelligent Design Creationism and the Constitution (2005)

On several occasions during the last eighty years, states have attempted to either prohibit the teaching of evolution in public school science classes or counter the teaching of evolution with mandatory references to the religious doctrine of creationism. The Supreme Court struck down examples of the first two generations of these statutes, holding that they violated the Establishment Clause of the First Amendment. A third generation of creationist legislation is now being proposed. Under this new generation of creationism legislation, science teachers would present so-called “intelligent design” theory as an alternative to evolution. Intelligent design theory asserts that a supernatural intelligence intervened in the natural world to dictate the nature and ordering of all biological species, which do not evolve from lower-to higher-order beings. This article considers whether these intelligent design creationism proposals can survive constitutional scrutiny. The authors analyze the religious, philosophical, and scientific details of intelligent design theory, and assess these details in light of the constitutional doctrine developed by the Court in its previous creationism decisions. The Article discusses several factors that pose problems for intelligent design theory, including the absence of objective scientific support for intelligent design, evidence of strong links between intelligent design and religious doctrine, the use of intelligent design to limit the dissemination of scientific theories that are perceived as contradicting religious teachings, and the fact that the irreducible core of intelligent design theory is what the Court has called the “manifestly religious concept of a God or Supreme Being. Based on these details, the authors conclude that intelligent design theory cannot survive scrutiny under the constitutional framework used by the Court to invalidate earlier creationism mandates.
High-resolution fast ion microscopy of single whole biological cells (2016)

High-resolution microscopy techniques have become an essential tool in both biological and biomedical sciences, enabling the visualization of biological processes at cellular and subcellular levels. For many years, these imaging techniques utilized conventional optical microscopes including those with confocal facilities. However, the spatial resolutions achieved were largely limited to around 200 nm, as determined by the diffraction of light. To overcome this diffraction barrier, considerable scientific and technological effort has resulted in the development of super-resolution optical-based techniques, scanning probe microscopies, and also techniques utilizing charged particles (e.g., energetic electrons and ions) or high-energy photons (e.g., X-ray), which exhibit much shorter de Broglie wavelengths. Among the charged particle techniques, those utilizing mega-electron-volt (MeV) ion beams appear to have unique advantages primarily because MeV ions can penetrate through several microns of biological tissue (e.g., whole cells) with little deflection in their trajectories, and hence spatial resolutions are maintained while traversing the sample. Recently, we have witnessed the significant development of MeV ion beam focusing systems in reducing beam dimensions well below 100 nm, such that single whole cell imaging at 20 nm spatial resolutions is now possible. In this review, two super resolution imaging modalities that utilize MeV highly focused ion beams are discussed: Scanning Transmission Ion Microscopy (STIM), which images the areal density of cells and gives an insight into the cellular structure, and Proton/Helium-ion Induced Fluorescence Microcopy (P/HeIFM), which images the fluorescence emission of fluorescent markers and probes used as labels within the cells. This review hopes to demonstrate the potential of MeV ion microscopy, which is still in its infancy, and describe the simultaneous use of STIM and P/HeIFM as a new and powerful multifaceted technology.