gebhart/patrepeval huggingface dataset:
Grid ID Management based on Distributed Agents using SPML (2006)

The Grid is a kind of computational infrastructures that interconnect high performance resources (e.g. super computer, mass storage, specialized experimental device) which are geologically distributed. Everyone can use the Grid network as a single system. To connect each resource with the Grid and provide service to every user who requires the resource, the Grid middleware should be installed. The most popular middleware is the Globus toolkit and GSI (Grid Security Infrastructure) takes charge the security part in the Globus toolkit. GSI is based on the PKI (Public Key Infrastructure) and supports certificate-based mutual authentication, SSO (Single Sign-On) using X. 509 proxy certificate and simple access control using Grid-map. However GSI is hard to manage the Grid account identifier and to process authentication or authorization management on each resource manually. This paper proposes agents-based distributed management architecture for the Grid environment. An administrator could maintain identical policies for resource at single point. SPML (Service Provisioning Markup Language) also enables the administrator to express various tasks and to support the extensibility. Proposed scheme utilizes central server only to manage the resources' policy, and maintains every policy in each resource. Therefore proposed scheme avoids SPF (Single Point of Failure) problem while running the Grid.
Chromite ore processing residue in Hudson County, New Jersey. (1991)

Chromite ore processing residue occurs at over 130 sites in Hudson County, New Jersey. Many of these sites are in urban residential areas. This waste is a result of 70 years of chromate and bichromate chemical manufacturing. At least 15% of the sites contain total chromium concentrations greater than 10,000 mg/kg, with hexavalent content ranging from about 1 to 50%. Continuing leaching of this waste results in yellow-colored surface water runoff and yellow deposits on the soil surface and inside basement walls. The chemistry, environmental fate, health effects, and human exposure potentials for this waste are described.
Separation and sorting of cells in microsystems using physical principles (2015)

In the last decade, microfabrication techniques have been combined with microfluidics and applied to cell biology. Utilizing such new techniques, various cell studies have been performed for the research of stem cells, immune cells, cancer, neurons, etc. Among the various biological applications of microtechnology-based platforms, cell separation technology has been highly regarded in biological and clinical fields for sorting different types of cells, finding circulating tumor cells (CTCs), and blood cell separation, amongst other things. Many cell separation methods have been created using various physical principles. Representatively, these include hydrodynamic, acoustic, dielectrophoretic, magnetic, optical, and filtering methods. In this review, each of these methods will be introduced, and their physical principles and sample applications described. Each physical principle has its own advantages and disadvantages. The engineers who design the systems and the biologists who use them should understand the pros and cons of each method or principle, to broaden the use of microsystems for cell separation. Continuous development of microsystems for cell separation will lead to new opportunities for diagnosing CTCs and cancer metastasis, as well as other elements in the bloodstream.
Iron and ferritin contents and distribution in human alveolar macrophages. (1988)

Previous investigations have shown that alveolar macrophages from cigarette smokers contain more iron than do macrophages obtained from nonsmokers. To localize intracellular iron and to help assess its potential for participation in the production of hydroxyl radicals, macrophages were fractionated and the ferritin and iron contents were measured in various cell fractions. Alveolar macrophages from seven smokers and six nonsmokers were lysed by nitrogen cavitation and centrifuged, first at 500 g and then at 11,000 g. Measured by radio-immunoassay, the total cellular ferritin was 133.8 +/- 33.2 ng and 782.0 +/- 177.8 ng per 1 x 10(6) macrophages (mean +/- SEM, p less than 0.01) obtained from nonsmokers and smokers, respectively. The total cellular iron contents were 7.5 +/- 0.6 nmol and 27.6 +/- 4.8 nmol per 1 x 10(6) macrophages (p less than 0.02) obtained from nonsmokers and smokers, respectively. The accumulation of iron by smokers' alveolar macrophages correlated with the number of cigarettes that had been smoked. Forty-two percent of the iron but only 9% of the ferritin was contained in the pellet obtained from centrifugation at 500 g. The pellet from the second centrifugation contained approximately 33% of the iron and 5% of the ferritin. The supernatant resulting from the second centrifugation contained 25% of the iron and 85% of the ferritin. Cigarette smoking did not appear to alter the intracellular distribution of either iron or ferritin. The ferritin content of bronchoalveolar lavage fluid was 0.10 +/- 0.04 micrograms/mg and 0.90 +/- 0.18 micrograms/mg albumin for nonsmokers and smokers, respectively (p less than 0.01).(ABSTRACT TRUNCATED AT 250 WORDS)
An Improved Approach to Accurately Model Shallow B and  BF 2 Implants in Silicon (1989)

In this paper, an improved modeling approach is described for simulating as‐implanted boron impurity profiles for B+and implants into single‐crystal silicon. This method uses the sum of two Pearson distribution functions to account for the nonchanneling and channeling components of the implant distribution. The ratio of the two Pearson functions varies with dose, which accounts for the change in the degree of channeling with dose. This modeling approach has been compared with experimentally measured SIMS profiles for a wide range of energies and doses for shallow B+ and implants. The excellent agreement indicates that this method offers a large improvement in simulation capability for B+ and implants. In addition, this method should be applicable to accurately model other impurities which have channeling tendencies.
SpliceAid: a database of experimental RNA target motifs bound by splicing proteins in humans (2009)

SpliceAid database is freely accessible at http://www.introni.it/splicing.html.
Human recombinant IL-4 suppresses the induction of human IL-2 induced lymphokine activated killer (LAK) activity. (1988)

The effect of recombinant human interleukin 4 (rhIL-4) on the induction in vitro of human lymphokine activated killer cell (LAK) activity was investigated. Peripheral blood mononuclear cells (PBMC) from normal healthy donors were incubated for 4 days with or without recombinant human interleukin-2 (rhIL-2) in the presence or absence of rhIL-4. LAK activity was measured against the NK-resistant colon adenocarcinoma cell line SW742, and NK mediated cytotoxicity was determined using NK sensitive K562 cells. Unlike previous reports using mouse effector cells, rhIL-4 neither induced LAK activity nor augmented the cytotoxic response induced by rhIL-2. In four out of six experiments there was a significant reduction of rhIL-2 induced LAK in the presence of rhIL-4, accompanied by a reduction of Tac antigen expression by rhIL-2 activated cells. Recombinant hIL-4 failed to influence the effector phase of the activated PBMC against SW742 or K562 targets.
When the Gypsies Come (1996)

Jeanne M. Burger, RN, MS,staff/charge nurse in coronary/medical ICU at Parkview Memorial Hospital in Ft. Wayne, Indiana, is an instructor for the RNBS program at Indiana Wesleyan University. She is on the board for a homeless shelter and has taught swimming for eighteen years.
On the performance of Flying Ad Hoc Networks (FANETs) utilizing near space high altitude platforms (HAPs) (2013)

High altitude platforms (HAPs) and Flying Ad Hoc Networks (FANETs) are some of the most promising technologies for both military and civilian near space wireless networks. HAP systems usually reside on stratospheric altitudes up to 25 km and have the advantages of flexible deployment, wide area coverage and line-of-sight propagation, compared to ground or satellite based systems. Also Unmanned Air Vehicles (UAVs) have the ability for persistent flight over periods of days to weeks which cannot be achieved by manned aircrafts. Thus, utilization of FANETs in conjunction with HAP stations would present numerous advantages over traditional networking. However one of the most challenging issue for FANETs is the awareness of the locations of the neighboring UAVs. It is vital for FANET scenarios in the sense of reliability, security and collision avoidance. In this study we investigate how HAP&FANET architectures can be usefully employed in such scenarios. We propose a Medium Access Control (MAC) protocol which we name as Location Oriented Directional MAC (LODMAC) protocol. LODMAC successfully handles the neighbor discovery and data transmission in parallel with the help of directional antennas. Also we present the capacity gain of LODMAC protocol which verify that it is a good alternative for HAP&FANET based scenarios.
A dynamic simulation of a two‐phase anaerobic digestion system for solid wastes (1987)

In this article, a two-phase system for the digestion of wastes with a high solid content is simulated. The solids are charged to the hydrolyzer and then leachate recirculation is activated until biodegradation is nearly complete. Several parameters are tested, namely moisture, leachate recirculation flow rate, and hydrolyzer-methanizer volume ratio. The results show that recirculation rate is an important parameter subject to optimization, with optimal values corresponding to hydrolyzer hydraulic retention times below 1 day. The quantity of recirculating water must be the highest possible. As a consequence, the organic load to the methanizer is reduced, making thus possible the use of a smaller methanizer volume.
Studies of Methemoglobin Concentrations of Three Human Erythrocyte Genotypes (Hb AA, Hb AS, and Hb SS) in the Presence of Five Antimalarial Drugs (2009)

Malaria remains the world's most devastating human parasitic infection. Our goal was to assess the capacity of increasing concentrations of five antimalarial drugs (Fansidar concentration in the presence of 0.2 g%, 0.4 g%, 0.6 g% and 0.8 g% (w/v) of the five antimalarial drugs. Results: The five antimalarial drugs showed a concentration dependent variability to cause the elevation of plasma methemoglobin concentration in the three genotypes. Specifically, Coartem TM , exhibited the highest propensity to elevate plasma methemoglobin concentration. However, the other four antimalarial drugs showed a statistically significant (P<0.05) but minimal effect to cause elevation of plasma methemoglobin concentration. For instance, with Hb AS blood sample and at drug concentration of 0.8g%, methaemoglobin concentrations (percentage) 0f 3.03±1.82, 2.65±0.45, 6.41±1.21, and 3.02±0.98 were obtained for halfan, quinine, coartem and chloroquine phosphate, respectively. The control value was 2.17±1.82% of methemoglobin. Conclusion: The oxidative potentials of these four antimalarial drugs and their metabolites in the red cells did not overwhelm the erythrocyte methemoglobin reducing capacity that could elicit the presentation in vitro toxic
Will QT Dispersion Play a Role in Clinical Decision‐Making? (1996)

(1) Dispersion of QT intervals is the difference between the longest and the shortest QT interval in the ECG. Owing to the relative ease of measurement and the perceived need for new markers of arrhythmogenicity, the method has attracted the interest of clinical investigators but has not reached the level of practical utility. (2) It is postulated that to pass the test of practical utility, the method must meet the following criteria: (a) standardization; (b) establishment of normal values; (c) established sensitivity and/or specificity for diagnosis and/or prognosis; and (d) uniqueness of relevant information. (3) Analysis of the data from the literature suggests that standardization of the method and the range of normal values have not been established, and that the method lacks specificity for separating healthy persons from patients with heart disease. (4) Large values, such as average QT dispersion > 65 msec, have been found predominantly in patients with serious, life-threatening ventricular tachyarrhythmias, and the largest values, i.e., > 110 msec in patients with congenital long QT syndrome. (5) The prognostic value of QT dispersion has been disputed, and the uniqueness of the relevant information has not been tested. (6) It is concluded that the acceptance of QT dispersion as a useful test in practice faces manifold and serious obstacles. It remains to be established whether these obstacles are insurmountable.
Efficient fair queueing using deficit round robin (1995)

Fair queuing is a technique that allows each flow passing through a network device to have a fair share of network resources. Previous schemes for fair queuing that achieved nearly perfect fairness were expensive to implement: specifically, the work required to process a packet in these schemes was O ( log ( n )), where n is the number of active flows. This is expensive at high speeds. On the other hand, cheaper approximations of fair queuing that have been reported in the literature exhibit unfair behavior. In this paper, we describe a new approximation of fair queuing, that we call Deficit Round Robin . Our scheme achieves nearly perfect fairness in terms of throughput, requires only O (1) work to process a packet, and is simple enough to implement in hardware. Deficit Round Robin is also applicable to other scheduling problems where servicing cannot be broken up into smaller units, and to distributed queues.
Analysis of the Chemical constituents of Stevia rebaudiana and its sweetness (2012)

Extraction and separation of the products from Stevia rebaudiana obtained through an industrial process afforded five purified compounds using silica gel column chromatography,reversed-phase Sephadex LH-20,ODS-A and MCI-GEL chromatography.Identification of by TLC,MS and NMR showed that the five purified compounds were 6-hydroxy-11-(β-D-glucopyranosyl)-2-cyclododecanone(Ⅰ),rebaudioside A(Ⅱ),rebaudioside B(Ⅲ),rebaudioside M(Ⅳ),and glucose(Ⅴ).The monomer I was a new compound.In silico prediction software was used to predict the sweetness of compounds Ⅰ,Ⅱ,Ⅲ and Ⅳ.Their sweetness values were predicted to be 113.6,225.0,325.0,and 29.4 times larger than sugar,respectively.
Reducing Multiple Object Motion Planning to Graph Searching (1986)

The motion planning problem for multiple objects is studied where an object is a 2-dimensional region whose sides are line segments parallel to the axes of ${\bf R}^2 $ and translations are the only motions allowed. Towards this end we analyze the structure of configuration space, the space of points that correspond to positions of the objects. In particular, we consider CONNECTED, the set of all points in configuration space that correspond to configurations of the objects where the objects form one connected component. We show that CONNECTED consists of faces of various dimensions such that if there is a path in CONNECTED between two 0-dimensional faces (vertices) of CONNECTED then there is a path between them along 1-dimensional faces (edges) of CONNECTED. It is known that if there is a motion between two configurations of CONNECTED then there is a path in CONNECTED between the configurations. Thus the existence of a motion between two vertices of CONNECTED implies a motion corresponding to a path along edges of CONNECTED. Hence the motion planning problem is reduced from a search of a high dimensional space to a graph searching problem. From this result it is shown that motion planning for rectangles in a rectangular boundary is in PSPACE. Since it is known that the problem is PSPACE-hard, we conclude it is a PSPACE-complete problem.
Comparison of Three Members of the Cysteine-rich Protein Family Reveals Functional Conservation and Divergent Patterns of Gene Expression (1997)

Members of the cysteine-rich protein (CRP) family are evolutionarily conserved proteins that have been implicated in the processes of cell proliferation and differentiation. In particular, one CRP family member has been shown to be an essential regulator of cardiac and skeletal muscle development. Each of the three vertebrate CRP isoforms characterized to date is composed of two copies of the zinc-binding LIM domain with associated glycine-rich repeats. In this study, we have addressed the biological significance of the CRP multigene family by comparing the subcellular distributions, biochemical properties, and expression patterns of CRP1, CRP2, and CRP3/MLP. Our data reveal that all three CRP family members, when expressed in adherent fibroblasts, associate specifically with the actin cytoskeleton. Moreover, all three CRP isoforms are capable of interacting with the cytoskeletal proteins alpha-actinin and zyxin. Together, these observations suggest that CRP family members may exhibit overlapping cellular functions. Differences between the three CRPs are evident in their protein expression patterns in chick embryos. CRP1 expression is detected in a variety of organs enriched in smooth muscle. CRP2 is restricted to arteries and fibroblasts. CRP3/MLP is dominant in organs enriched in striated muscle. CRP isoform expression is also developmentally regulated in the chick. Our findings suggest that the three CRP family members perform similar functions in different muscle derivatives. The demonstration that all members of the CRP family are associated with cytoskeletal components that have been implicated in the assembly and organization of filamentous actin suggests that CRPs contribute to muscle cell differentiation via effects on cytoarchitecture.
Next generation manufacturing execution system (mes) enabling fully integrated fab automation in 300mm technology development and manufacturing (2005)

After a three year development and integration effort, Intel has successfully implemented a next generation MES system (referred to as MES300 henceforth this paper) in its state-of-the-art Technology Development fab DID, Oregon. MES300 provides integration of all MES functionality in an extensible framework based architecture, thereby enabling delivery of an active, fab event driven suite of capabilities. The new system provides flexibility in modeling and executing technology development in an automated fab operations environment, thereby delivering world-class information turns crucial for rapid process development. In addition, the new system enables fully automated fab operations for efficient high-volume manufacturing. MES300 is currently being simultaneously deployed in two other 300 mm high-volume manufacturing fabs as part of the 65 nm process technology transfer. This paper will include the following sections: (a) 300 mm automation drivers; (b) 300 mm technology and manufacturing requirements, legacy MES system deficiencies; (c) key elements of the next generation MES architecture implemented at Intel; (d) brief review of system design, development, test and deployment strategy; (e) sample of key capabilities delivered to date in DID/65 nm generation.; and (f) look-ahead on how MES300 is being leveraged to delivering industry leading automation capabilities in the next couple of year
Dissecting the Membrane Binding and Insertion Kinetics of a pHLIP Peptide (2008)

When it is bound to lipid bilayers, the conformation and location of the membrane pH (low) insertion peptide (pHLIP) depend on pH. This unique feature allows us to explicitly measure the kinetics leading to different membrane-bound states of pHLIP using a model membrane and stopped-flow technique. Our results show that the membrane association kinetics of pHLIP are multiexponential and are consistent with a parallel membrane interaction mechanism. Interestingly, our results also show that the overall rate at which the membrane-inserted state is formed is almost identical to that of formation of the surface-bound state, while prebinding slows the rate of peptide insertion.
Anti-oxidant effects of cinnamon (Cinnamomum verum) bark and greater cardamom (Amomum subulatum) seeds in rats fed high fat diet. (1999)

In order to gain insight into the antioxidant effect of cinnamon (Cinnamomum verum; Lauraceae) and cardamom (Amomum subulatum; Zingiberaceae) hepatic and cardiac antioxidant enzymes, glutathione (GSH) content and lipid conjugated dienes were studied in rats fed high fat diet along with cinnamon or cardamom. The antioxidant enzyme activities were found to be significantly enhanced whereas GSH content was markedly restored in rats fed a fat diet with spices. In addition, these spices partially counteracted increase in lipid conjugated dienes and hydroperoxides, the primary products of lipid peroxidation. Thus, it appears that these spices exert antioxidant protection through their ability to activate the antioxidant enzymes.
The epidemiology of multiple births (1999)

On the basis of MEDLINE and manual searches, we examined the main papers in the English literature regarding risk factors for spontaneous (i.e. not related to fertility drug use) multiple births. The constant frequency of monozygotic (MZ) pregnancies over time and in different geographical areas suggests that the determination of MZ twins is largely unchanged over time, and that a genetic mechanism may have a role. In contrast, temporal and geographical trends observed in dizygotic (DZ) pregnancies suggest that environmental factors play a role in determining this condition. At present, maternal age and hereditary components are the best-defined determinants for spontaneous multiple births.
Antifungal Activity of Lemon Grass Oil and Lemon Grass Oil Cream (1996)

Lemon grass oil was extracted by steam distillation of wilted leaves of lemon grass (Cymbopogon citratus (DC.) Stapf.) cultivated in Thailand. The minimum inhibitory concentration (MIC) and minimum lethal concentration (MLC) of this oil and citral against 35 clinical isolates of 4 dermatophytes (Trichophyton mentagrophytes, T. rubrum, Epidermophyton floccosum, and Microsporum gypseum) were determined by agar dilution method. It was found that the MIC and MLC of lemon grass oil were higher than those of citral. The most resistant strain was M. gypseum followed by T. rubrum, T. mentagrophytes and E. floccosum, respectively. The mode of action of lemon grass oil and citral were proven to be fungicidal. The comparative study of the efficacy of cream containing four different concentrations (1.5%, 2%, 2.5% and 3%) of lemon grass oil was performed in vitro by hole diffusion assay. The 2.5% lemon grass oil was demonstrated to be the minimum concentration for preparation of an antifungal cream for subsequent clinical study.
Reborn from the Ashes: Turning Organic Molecules to Antimicrobial Carbon Quantum Dots (2017)

Using polyamines as the initial organic raw material and by applying simple pyrolysis methods, super cationic carbon quantum dots (CQDs) can easily be made. Since polyamines are natural products and the synthesis procedure is green, these polyamine-derived CQDs display low toxicity and high biocompatibility but possess high antibacterial activity. In addition, polyamine-derived CQDs display other unique properties, such as facilitation of wound healing and passage through the tight junction, which make them a very promising bactericide in future clinical applications.