gebhart/patrepeval huggingface dataset:
Preparation of Cationic Dinuclear Hydrido Complexes of Ruthenium, Rhodium, and Iridium with Bridging Thiolato Ligands and Their Reactions with Nitrosobenzene (1999)

A series of cationic dinuclear hydrido complexes with bridging thiolato ligands [CpMH(&mgr;-SPr(i))(2)MCp][OTf] (4, M = Ru; 6a, M = Rh; 7a, M = Ir; Cp = eta(5)-C(5)Me(5), OTf = OSO(2)CF(3)) were synthesized by treatment of the corresponding chloro complexes [CpRuCl(&mgr;-SPr(i))(2)Ru(OH(2))Cp][OTf] (1) or [CpM(&mgr;-Cl)(&mgr;-SPr(i))(2)MCp][OTf] (2, M = Rh; 3, M = Ir) with HSiEt(3). The dirhodium and diiridium complexes 6 and 7 have been shown to possess a bridging hydrido ligand by crystallographic analysis, while the diruthenium complex 4 is proposed to have a terminal hydrido ligand that undergoes facile migration between the two ruthenium centers in solution. Complexes 4, 6a, and 7a reacted with nitrosobenzene to give the paramagnetic dinuclear nitrosobenzene complexes [CpM(&mgr;-PhNO)(&mgr;-SPr(i))(2)MCp](+) (M = Ru, Rh, Ir) along with azoxybenzene. The molecular structures of the three nitrosobenzene complexes have been determined by X-ray diffraction study to reveal that in each case nitrosobenzene acts as a &mgr;-eta(1):eta(1)-N,O ligand. Judging from the molecular structures and the ESR spectra, the unpaired electron is considered to be located mainly on the nitrosobenzene ligand, at least in the diruthenium and dirhodium complexes. On the other hand, complex 2 reacted with nitrosobenzene to give the incomplete cubane-type trinuclear cluster [(CpRh)(3)(&mgr;-Cl)(2)(&mgr;(3)-S)(&mgr;-SPr(i))](+), whose molecular structure has also been determined crystallographically.
Mycophenolate Mofetil for Induction and Maintenance of Remission in Microscopic Polyangiitis with Mild to Moderate Renal Involvement—A Prospective, Open-Label Pilot Trial (2010)

MMF represents an alternative to CYC for induction and maintenance of remission in patients with MPO-ANCA-associated MPA with mild to moderate renal disease.
A Comparison of Ligament Tensions Between Intra- and Extra-Articular Measurement in Anterior Cruciate Ligament Reconstruction (2015)

Anterior cruciate ligament (ACL) reconstruction is one of the treatments of ACL injuries. In the surgery, the reconstructed ligament should be properly tensioned to provide a normal ligament behavior. However, the ligament tension has been measured with an extra-articular technique in past studies, while the intra-articular ligament tension is still unknown. The purpose of this study is to compare the ligament tensions between intra- and extra-articular measurements in the ACL reconstruction. Intra-articular measurement employs a micro-force sensor designed with a width and thickness same as those of the reconstructed ligament. This study performed two experiments (i.e., sensor accuracy and cadaveric study). In the sensor accuracy experiment, the accuracy of the sensor was about 3% until an applied force of 100 N. In the cadaveric study, the results of the intra- and extra-articular measurement tensions were 13.6±3.9 N and 18.7±1.3 N ( n = 6), respectively. The significant difference in student t-test (p-value was 0.026) between the intra- and extra- articular measurements was observed. The bending angle and friction between the graft and bone tunnel, and the shape of the intra-articular edge of tibial bone tunnel affected the intra-articular measurement in ACL reconstruction.
Displasia septóptica (síndrome de Morsier): a propósito de un caso (2008)

It is an infrequent disease and its causation is uncertain, although the predominant hypothesis suggests a genetic foundation. The mechanism by which it is transmitted by inheritance is unknown. The age of the mother is characteristically low; it is known that over half the children affected by this condition were born to mothers below the age of 20. It may be accompanied by liver damage and it is essential to establish a diagnosis and treatment as early as possible. Prognosis is general favourable.
Pemimpin transformasional di lembaga pendidikan Islam (2010)

Pemimpin transformasional di lembaga pendidikan Islam fokus pada transformasi personal dan pada akhirnya transformasi lembaga. Ia memerdekakan mereka dari sikap inkonsisten, pesimis, mengeluh dan lainnya yang menghambat transformasi personal. Ia menggerakkan mereka dengan memenangkan hati, pikiran, emosi dan spiritualitas, menjauh dari cara-cara penguasaan dan merekayasa karena kemerdekaan menjadi visinya. Kelebihan buku ini adalah pembahasannya yang tuntas mulai dari dasar-dasar teoritik sampai contoh praktiknya yang dilengkapi dengan beberapa skema teoritik dan strategi penerapannya. Buku ini juga dapat diterapkan oleh Anda pemimpin organisasi apapun, dan bisa menjadi bacaan dosen, guru, dan mahasiswa dan pecinta keilmuan.
Aberrant Aggregation Behavior in Cationic Gemini Surfactants Investigated by Surface Tension, Interfacial Tension, and Fluorescence Methods (1999)

Bis(quaternary ammonium halide) surfactants (gemini surfactants) having, variously, diethyl ether, monohydroxypropyl, and dihydroxybutyl spacer groups have been investigated by surface tension, interfacial tension, and steady-state fluorescence techniques. The critical micelle concentration (cmc) and area per molecule (Amin) are shown to deviate from the expected patterns of behavior as the number of carbon atoms in the alkyl chain (n) increases beyond a certain maximum. This aberrant behavior is observed at the hydrocarbon/water as well as the aqueous/air interface. The unexpected values of the physicochemical parameters at long alkyl chain length have been interpreted on the basis of a concentration region in which submicellar or multilayer structures are forming. Fluorescence measurements provide confirmation of cmc values by an alternative technique. Comparison of the fluorescence emission maxima profiles of the gemini surfactants with those of their monoquaternary analogues demonstrates that there is a continuously changing shape with change in n for the geminis, whereas the profiles for nongeminis are invariant. Long-chain geminis exhibit a gradually sloping sigmoidal profile, indicating a variety of environments experienced by pyrene-3-carboxaldehyde between the totally aqueous environment at low surfactant concentration and the hydrophobic (entirely micellar) environment at high surfactant concentration. The large variation in the polarity of the probe environment between these two extremes may be attributed to the formation of submicellar structures.
Operational Characteristics of Four Commercially Available Personal Cooling Vests (1997)

Personal thermoregulatory systems which provide chest cooling are used in the industrial and aerospace environments to alleviate thermal stress. However, little information is available regarding the physiologic and circulatory changes produced by routine operation of these systems. The objectives of this study were to compare the effectiveness of two passive and two active cooling vests, and to measure the body temperature and circulatory changes produced by each cooling vest configuration. The MicroClimate Systems and the Life Enhancement Tech(LET) lightweight liquid cooling vests, the Steele Vest and LET's Zipper Front Garment were used to cool the chest region of 11 male and 10 female subjects (25 to 55 yr.) in this study. Calf, forearm and finger blood flows were measured using a tetrapolar impedance rheograph. The subjects, seated in an upright position at normal room temperature (approx.21 C), were tested for 60 min. with the cooling system operated at its maximum cooling capacity. Blood flows were recorded continuously using a computer data acquisition system with a sampling frequency of 250 Hz. Oral, right and left ear temperatures and cooling system parameters were logged manually every 5 min. Arm, leg, chest and rectal temperatures; heart rate; respiration; and an activity index were recorded continuously on a URI Inc. Biolog ambulatory monitor. In general, the male and female subjects' rectal and ear temperature responses to cooling were similar for all vest configurations tested. Oral temperatures during the recovery period were significantly (P<0.05) lower than during the control period, approx.0.2 - 0.5 C, for both men and women wearing any of the four different garments. The corresponding car temperatures were significantly (P<0.05) decreased approx.0.2 - 0.3 C by the end of the recovery period. Compared to the control period, no significant differences were found in rectal temperatures during cooling and recovery periods. These results show that all vest configurations elicit a similar thermal response in both male and female subject groups. However, subject population variance was rather large and may have masked differences between the vests. One vest may prove more effective than another for a given individual, and experience is the only means of determining this.
The ability of Salmonella typhimurium to produce the siderophore enterobactin is not a virulence factor in mouse typhoid (1985)

One of the nonspecific defense mechanisms of higher animals is their ability to limit iron availability to infecting bacteria. Thus it has been argued that all pathogenic bacteria must have special mechanisms to obtain iron in the host environment. Salmonella typhimurium is known to produce a siderophore, enterobactin, with which it can obtain iron from host transferrin. Previous studies have indicated that the production of this molecule is necessary for the ability of intraperitoneally injected. S. typhimurium cells to cause mouse typhoid, a largely intracellular infection. We have reexamined this finding with wild-type S. typhimurium and isogenic strains carrying the nonenterobactin-producing mutation ent-1 or ent-7. Our findings demonstrate that, although enterobactin production is necessary for growth in normal mouse serum, it does not affect the ability of S. typhimurium to cause mouse typhoid. Based on these findings and published results of other investigators on the role of siderophores in intracellular pathogens, a more comprehensive investigation of the importance of siderophores in intracellular infections may be warranted.
<title>Compact Z-pinch EUV source for photolithography</title> (2001)

According to Sematech International's analysis extreme ultraviolet (EUV) photolithography is one of the most promising approaches for next generation lithography (NGL). The insertion point of NGL is likely at the 50 nm node. To establish EUV lithography all basic technologies have to be developed t material suppliers, source suppliers, coating manufacturers, optics, lens and tool manufacturers, mask houses, pellicle manufacturers and resist suppliers over the next years. To achieve the required throughput in production various concepts of EUV sources are currently under investigation. Here we discuss new results of design studies on gas discharge Z-pinch sources. Form the EUV source 1 W output power at 100 Hz repetition rate could be obtained in continuous operation. Pulse energy stability is 4% (sigma). In burst operation repetition rate of up to 400 Hz is possible with the current design.
A Phosphotransferase Activity of the<i>Bacillus subtilis</i>Sporulation Protein Spo0F That Employs Phosphoramidate Substrates (1996)

Transient phosphorylation at an aspartate residue on the Spo0F protein is a central step in the phosphorelay signal transduction pathway controlling sporulation in Bacilli. The response regulator Spo0F-P is stable to hydrolysis (t1/2 > 24 h at 23 degrees C in the absence of Mg2+), allowing the use of nondenaturing PAGE to separate the phosphorylated and non-phosphorylated forms of Spo0F. Using this novel assay, phosphoramidate containing compounds were found to specifically phosphorylate Spo0F, a reaction that requires the presence of a divalent metal, but mixed phosphate-carboxylate compounds did not act as phospho donors. Rapid hydrolysis of Spo0F-P generated with phosphoramidate by proteins downstream in the phosphorelay (Spo0B and Spo0A) is consistent with phosphorylation at the active site of Spo0F. The initial rate of Spo0F-P formation from phosphoramidate displays Michaelis-Menten kinetics, providing evidence for the proposal that response regulators, such as Spo0F, function as phosphoryl transferase enzymes (McCleary et al., 1993). The results establish that Spo0F functions as a phosphoryl transferase that uses exclusively a phosphoramidate rather than an acyl phosphate as substrate during autophosphorylation.
A 1-Watt Ku-band power amplifier in SiGe with 37.5% PAE (2016)

This paper demonstrates a 1-Watt output power amplifier MMIC operating from 13.5GHz to 14.5GHz (Ku-band). The power amplifier employs an on-chip integrated 16-way in-phase output current combiner to achieve the required output power. Implemented in a 0.25-μm SiGe:C BiCMOS technology, the power amplifier achieves a power-added efficiency of 37.5% at 14.1GHz with greater than 35.5% across the band of interest.
Critical Target and Dose and Dose-Rate Responses for the Induction of Chromosomal Instability by Ionizing Radiation (1999)

To investigate the critical target, dose response and dose-rate response for the induction of chromosomal instability by ionizing radiation, bromodeoxyuridine (BrdU)-substituted and unsubstituted GM10115 cells were exposed to a range of doses (0.1-10 Gy) and different dose rates (0.092-17.45 Gy min(-1)). The status of chromosomal stability was determined by fluorescence in situ hybridization approximately 20 generations after irradiation in clonal populations derived from single progenitor cells surviving acute exposure. Overall, nearly 700 individual clones representing over 140,000 metaphases were analyzed. In cells unsubstituted with BrdU, a dose response was found, where the probability of observing delayed chromosomal instability in any given clone was 3% per gray of X rays. For cells substituted with 25-66% BrdU, however, a dose response was observed only at low doses (<1.0 Gy); at higher doses (>1.0 Gy), the incidence of chromosomal instability leveled off. There was an increase in the frequency and complexity of chromosomal instability per unit dose compared to cells unsubstituted with BrdU. The frequency of chromosomal instability appeared to saturate around approximately 30%, an effect which occurred at much lower doses in the presence of BrdU. Changing the gamma-ray dose rate by a factor of 190 (0.092 to 17.45 Gy min(-1)) produced no significant differences in the frequency of chromosomal instability. The enhancement of chromosomal instability promoted by the presence of the BrdU argues that DNA comprises at least one of the critical targets important for the induction of this end point of genomic instability.
Further studies on a novel class of genetic variants of the L1210 cell with increased folate analogue transport inward. Transport properties of a new variant, evidence for increased levels of a specific transport protein, and its partial characterization following affinity labeling. (1988)

Studies are reported on the characterization of a new isolate within a novel class of variants of the L1210 cell exhibiting markedly increased transport inward of folate analogues. This variant (L1210/R83), which was selected in the presence of the antifolate metoprine, exhibited a 40-fold increase in [3H]aminopterin influx compared to parental cells and a modest (4-5-fold) increase in [3H]aminopterin efflux. The increase in influx was associated with a comparable increase in influx Vmax for the one-carbon, reduced folate transport system and the same increase in the amount of specific binding of [3H]aminopterin on the cell surface. Values for influx Km for [3H]aminopterin and specificity for various folate structures were unchanged. The alteration in influx Vmax and more rapid efflux accounted for the different level of intracellular exchangeable level of drug at steady state in this variant compared with parental L1210 cells. Otherwise, membrane potential was unchanged. The N-hydroxysuccinimide ester of [3H]aminopterin was used to covalently label the specific binding protein for folate compounds in the plasma membrane of variant and parental L1210 cells. Incorporation of label into this protein was stable under a variety of conditions and accounted for 97 and 52% of total cellular labeling, respectively, for membrane derived from R83 and parental L1210 cells at a reagent concentration of 20 nM. Specific affinity labeling on the surface of parental and variant cells was decreased in the presence of aminopterin, methotrexate, or 5-formyltetrahydrofolate, but not in the presence of folic acid. Also, [3H]aminopterin influx in these cells was inhibited by the N-hydroxysuccinimide ester of aminopterin or methotrexate, but not the N-hydroxysuccinimide ester of folic acid. These findings, in addition to the increased affinity labeling of this variant, which corresponds to the increase in influx of [3H] aminopterin also seen, appears to identify the affinity labeled protein as a component of the "classical" one-carbon, reduced folate transport system in these cells. The affinity labeled protein from each cell type was solubilized in sodium dodecyl sulfate or extracted in detergent in the presence of proteinase inhibitors and was found to elute from Sephacryl S-300 and migrate during sodium dodecyl sulfate-polyacrylamide gel electrophoresis as a single peak of Mr = 45,000-48,000. Recovery of labeled binding protein in these fractions from R83 variant cells was approximately 40 times greater than that from parental cells.(ABSTRACT TRUNCATED AT 400 WORDS)
Prospective study of early detection of pharyngeal superficial carcinoma with the narrowband imaging laryngoscope (2008)

The NBI laryngoscope may play an important role in the diagnosis and treatment of superficial carcinoma in the oropharynx and hypopharynx.
Photochemical Identification of the Binding Region for (S)-Semotiadil on Sodium Channels: Comparison with That for (R)-Semotiadil on Skeletal Muscle Calcium Channel (2003)

To clarify the recognition site of (S)-semotiadil in the Na+ channels,\nwe employed photoaffinity labeling with (S)-[3H]-D51-4700, an azidophenyl\nderivative of (S)-semotiadil, to Na+ channel preparations from rat brains and\nporcine hearts, and the results were compared with those by (R)-enantiomer to\nskeletal muscle Ca2+ channel. Protease-digestion of the photolabeled Na+ channels\nfollowed by quantitative immunoprecipitation assay using a site-directed\nantibody, revealed that 10- and 13- kDa fargments of brain and cardiac Na+\nchannels, respectively, were located within the regions including IVS6. These\nregions are corresponding to the 8.3 kDa fragment photolabled by (R)-[3H]-D51-\n4700 in the skeletal muscle Ca2+ channel. Interestingly, however, the\nphotoincorporation of (S)-[3H]-D51-4700 into the Na+ channel was 2-3 times\nhigher than that of (R)-isomer; and visa versa in the Ca2+ channels.
Analyzing the potential benefits of CDN augmentation strategies for internet video workloads (2013)

Video viewership over the Internet is rising rapidly, and market predictions suggest that video will comprise over 90\% of Internet traffic in the next few years. At the same time, there have been signs that the Content Delivery Network (CDN) infrastructure is being stressed by ever-increasing amounts of video traffic. To meet these growing demands, the CDN infrastructure must be designed, provisioned and managed appropriately. Federated telco-CDNs and hybrid P2P-CDNs are two content delivery infrastructure designs that have gained significant industry attention recently. We observed several user access patterns that have important implications to these two designs in our unique dataset consisting of 30 million video sessions spanning around two months of video viewership from two large Internet video providers. These include partial interest in content, regional interests, temporal shift in peak load and patterns in evolution of interest. We analyze the impact of our findings on these two designs by performing a large scale measurement study. Surprisingly, we find significant amount of synchronous viewing behavior for Video On Demand (VOD) content, which makes hybrid P2P-CDN approach feasible for VOD and suggest new strategies for CDNs to reduce their infrastructure costs. We also find that federation can significantly reduce telco-CDN provisioning costs by as much as 95%.
James' Parents, [1872] August [n.d.] (1872)

full date listed as [1872, 5] August; Jobe dates this as 8-14-72; repository information indicates this is the MWJ letter of August [5]
Assessment of Sexual Function and Attitudes in Female Patients With Functional Bowel Disorders (2014)

Introduction: There is limited empirical consideration of the sexual health effects in pelvic floor disorders for women, especially impacting sexuality. Addressing sexual function domains affected by chronic constipation (CC) and fecal incontinence (FI) may improve a patient’s quality of life, relationships, and better prepare physicians to address social aspects of functional bowel disorders. Examine the relationships between CC, FI and sexual dysfunction related to patients’ attitude toward sharing their sexual health history in a medical setting. Methods: A sub-analysis of a cross-sectional study of 445 adult female patients in gynecology, urology, and gastroenterology clinics at a tertiary referral health system from January 2014 through June 2014. Sixty-five (77% female, mean age =43, and 66% white) women with CC or FI that were referred for anorectal manometry (ARM) were included. All questionnaires included demographics, questions about sexual health, and the female sexual function index (FSFI). An abnormal FSFI was defined as a cumulative score ≤26.55, with higher scores indicating better sexual function. Comparisons of sample proportions and function indices were performed using Pearson’s chi square test, independent t-tests, and generalized linear models. Results: Women undergoing ARM for CC or FI had a mean total FSFSI score of 13.16 vs. the general sample mean 18.30 (p=.003). The FSFI domain scores of ARM patients were significantly lower than the general sample for desire, arousal, lubrication, and satisfaction (Table 1). Patients with FI were significantly more likely than those with CC to provide their sexual health history by filling out a form (35% vs. 13.9%) as opposed to with their ob/gyn or urologist in person (40% vs. 52.8%) (p= 0.035).Table 1Conclusion: Sexual dysfunction was more common in women affected by CC and FI than the general sample of adult women in gynecology, urology and gastroenterology clinics. Results suggest that functional bowel disorders do not uniformly affect the sexual lives and attitudes of women. This should be taken into consideration during patient/physician interaction and medical treatment. Further investigation between the relationship between pelvic floor disorders and sexual dysfunction is warranted.
The impact of HIV/AIDS on labour productivity in Kenya (2004)

These results provide empirical estimates of the impact of HIV/AIDS on labour productivity. As workers often bring unrecorded 'helpers', actual differences may be greater. Decreased attendance and output may put sick workers in jeopardy of losing their jobs and impose financial burdens on employers.
Location of the Bacillus subtilis temperate bacteriophage phi 105 attP attachment site (1986)

Chromosomal DNAs of lysogens of phi 105 and phi 105 DI:1t were digested with restriction enzymes EcoRI and HpaI and were probed with nick-translated mature phi 105 DNA. Altered bacteriophage-specific bands in the lysogens were detected, indicating that the phage integrates into the host chromosome at a single site, probably via a Campbell-type circular intermediate. The phage attachment site is centrally located in the phage genome and lies between the phage immunity region and the nonessential deletable region of phi 105.