gebhart/patrepeval huggingface dataset:
Meteorological and Oceanographic Observations on I. N. S. INVESTIGA TOR (March-ApriI1952) (1954)

This paper describes the observations taken on I.N.S. Investigator, during the ship's last survey season in the Andaman Islands, The work done during the voyage was (a) measurement of temperature, density and salinity in the surface waters of the Arabian Sea and Bay of Bengal, and (b) measurement of the humidity wind gradient in the lower layers of the atmosphere above the sea. The observations of salinity during the voyage have been compared with the earlier work of Sewell (1938). In addition, attempts have been made to estimate evaporation from the observations of humidity gradient. The wind observations have also been analysed to see what agreement they give with Rossby's earlier results.
A Review of Occupational Therapy Research and Development Activity in Scotland, Northern Ireland and Wales (2013)

Introduction: A review was undertaken of the College of Occupational Therapists' 2002 scoping study of occupational therapy research and development activity in Scotland, Northern Ireland and Wales in order to assess the developments in infrastructure supporting occupational therapy research, to highlight opportunities available to occupational therapists and to identify how the College could best support members' research activities. Method: Within each nation, a literature review and focus group were undertaken. A feature of the research was the opportunity for a student occupational therapist from each country to be involved as co-researcher. Findings: The findings revealed a considerable investment and increase in research capacity developments in all three countries, recognising the need to develop the evidence base to underpin occupational therapy interventions. Barriers to progressing research activity included time and research topic prioritisation, and workplace cultures that did not promote research-related activities. The College of Occupational Therapists was considered to have a key role in influencing policy directions and the launch of the United Kingdom Occupational Therapy Research Foundation was viewed as an opportunity to support occupation-focused research and capacity development. Conclusion: Significant progress reflects the investment in research infrastructure, although further effort is needed to change cultural impacts.
Partial indexing for nonuniform data distributions in relational DBMS's (1994)

It is well known that the effectiveness of relational database systems is greatly dependent on the efficiency of the data access strategies. For this reason, much work has been devoted to the development of new access techniques, supported by adequate access structures such as the B/sup +/trees. The effectiveness of the B/sup +/tree also depends on the data distribution characteristics; in particular, poor performance results when the data show strong key value distribution unbalancing. The aim of this paper is to present the partial index: a new access structure that is useful in such cases of unbalancing, as an alternative to the B/sup +/tree unclustered indexes. The access structures are built in the physical design phase, and at execution (or compilation) time, the optimizer chooses the most efficient access path. Thus, integration of the partial indexing technique in the design and in the optimization process are also described.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Notes- Preparation of Crystalline Diphenyldiazomethane (1959)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTNotes- Preparation of Crystalline DiphenyldiazomethaneJ MillerCite this: J. Org. Chem. 1959, 24, 4, 560–561Publication Date (Print):April 1, 1959Publication History Published online9 July 2003Published inissue 1 April 1959https://pubs.acs.org/doi/10.1021/jo01086a603https://doi.org/10.1021/jo01086a603research-articleACS PublicationsRequest reuse permissionsArticle Views1122Altmetric-Citations155LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Estimation of apparent thermal conductivity of carrot purée during freezing using inverse problem (2009)

Summary This article presents an inverse problem to determine the apparent thermal conductivity of carrot purée during the freezing process. The heat diffusion equation with the enthalpy model is solved to estimate the thermal conductivity. A modern meta‐heuristic of evolutionary computation field called Differential Evolution (DE) is applied for the solution of inverse problem. Experiments were performed to estimate the thermal conductivity of the carrot purée as a function of temperature, using two piecewise functions. A best least square fitting between the experimental and predicted temperature curves during freezing conditions is obtained using DE. Statistical analysis are considered with Gaussian error of 0.05 and zero mean showing than the results for one piecewise function are more stable than with another piecewise function. Good agreement between the reported and estimated temperature curves was obtained. The apparent thermal conductivity was observed to decrease asymptotically with temperature in the range [−40 °C, 0 °C] and stay approximately a constant value for temperatures bigger than 0 °C.
Expression of human a-L-fucosyltransferase gene homologs in monkey kidney COS cells and modification of potential fucosyltransferase acceptor substrates by an endogenous glycosidase (1999)

Previous investigations on the monkey kidney COS cell line demonstrated the weak expression of fucosylated cell surface antigens and presence of endogenous fucosyltransferase activities in cell extracts. RT-PCR analyses have now revealed expression of five homologs of human fucosyltransferase genes, FUT1, FUT4, FUT5, FUT7, and FUT8, in COS cell mRNA. The enzyme in COS cell extracts acting on unsialylated Type 2 structures is closely similar in its properties to the alpha1,3-fucosyltransferase encoded by human FUT4 gene and does not resemble the product of the FUT5 gene. Although FUT1 is expressed in the COS cell mRNA, it has not been possible to demonstrate alpha1,2-fucosyltransferase activity in cell extracts but the presence of Le(y) and blood-group A antigenic determinants on the cell surface imply the formation of H-precursor structures at some stage. The most strongly expressed fucosyltransferase in the COS cells is the alpha1,6-enzyme transferring fucose to the innermost N -acetylglucosamine unit in N -glycan chains; this enzyme is similar in its properties to the product of the human FUT8 gene. The enzymes resembling the human FUT4 and FUT8 gene products both had pH optima of 7.0 and were resistant to 10 mM NEM. The incorporation of fucose into asialo-fetuin was optimal at 5.5 and was inhibited by 10 mM NEM. This result initially suggested the presence of a third fucosyltransferase expressed in the COS cells but we have now shown that triantennary N- glycans with terminal nonreducing galactose units, similar to those present in asialo-fetuin, are modified by a weak endogenous beta-galactosidase in the COS cell extracts and thereby rendered suitable substrates for the alpha1,6-fucosyltransferase.
Insights into the Structure, Function, and Ligand Discovery of the Large Neutral Amino Acid Transporter 1, LAT1 (2018)

The large neutral amino acid transporter 1 (LAT1, or SLC7A5) is a sodium- and pH-independent transporter, which supplies essential amino acids (e.g., leucine, phenylalanine) to cells. It plays an important role at the Blood⁻Brain Barrier (BBB) where it facilitates the transport of thyroid hormones, pharmaceuticals (e.g., l-DOPA, gabapentin), and metabolites into the brain. Moreover, its expression is highly upregulated in various types of human cancer that are characterized by an intense demand for amino acids for growth and proliferation. Therefore, LAT1 is believed to be an important drug target for cancer treatment. With the crystallization of the arginine/agmatine antiporter (AdiC) from <i>Escherichia Coli</i>, numerous homology models of LAT1 have been built to elucidate the substrate binding site, ligand⁻transporter interaction, and structure⁻function relationship. The use of these models in combination with molecular docking and experimental testing has identified novel chemotypes of ligands of LAT1. Here, we highlight the structure, function, transport mechanism, and homology modeling of LAT1. Additionally, results from structure⁻function studies performed on LAT1 are addressed, which have enhanced our knowledge of the mechanism of substrate binding and translocation. This is followed by a discussion on ligand- and structure-based approaches, with an emphasis on elucidating the molecular basis of LAT1 inhibition. Finally, we provide an exhaustive summary of different LAT1 inhibitors that have been identified so far, including the recently discovered irreversible covalent inhibitors.
Automatic extraction of 3‐D seismic horizons (1983)

PreviousNext No AccessSEG Technical Program Expanded Abstracts 1983Automatic extraction of 3‐D seismic horizonsAuthors: N. KeskesPh. ZaccagninoD. RetherP. MermeyN. KeskesINRIA, Ph. ZaccagninoELF Aquitaine, France, D. RetherELF Aquitaine, France, and P. MermeyELF Aquitaine, Francehttps://doi.org/10.1190/1.1893729 SectionsAboutPDF/ePub ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinked InRedditEmail Permalink: https://doi.org/10.1190/1.1893729FiguresReferencesRelatedDetailsCited ByInteractive seismic interpretation with piecewise global energy minimizationSeismic attributes — A historical perspectiveGEOPHYSICS, Vol. 70, No. 5Horizon picking in 3D seismic data volumesMachine Vision and Applications, Vol. 15, No. 4Horizon Picking in 3D Seismic Images24 June 2003 SEG Technical Program Expanded Abstracts 1983ISSN (print):1052-3812 ISSN (online):1949-4645Copyright: 1983 Pages: 646 publication data© 1983 Copyright © 1983 Society of Exploration GeophysicistsPublisher:Society of Exploration Geophysicists HistoryPublished: 24 Mar 2005 CITATION INFORMATION N. Keskes, Ph. Zaccagnino, D. Rether, and P. Mermey, (1983), "Automatic extraction of 3‐D seismic horizons," SEG Technical Program Expanded Abstracts : 557-559. https://doi.org/10.1190/1.1893729 Plain-Language Summary PDF DownloadLoading ...
Mechanisms of Neuroinflammation (2017)

"Mechanisms of Neuroinflammation" book explains how the neuronal cells become swollen at the moment of the blood-brain barrier disruption and how they lose their immunological isolation. A cascade of cytokines and immune cells from the bloodstream enters the nervous system, inflaming neurons and activating the glia. This produces a neuroinflammatory process that can generate different neurodegenerative diseases. Better understanding of mechanisms that are activated at the time when the damage to the brain occurs could lead to the development of suitable therapies that revert the neuronal inflammation and thus prevent further damage to the nervous system.
Vacuum ultraviolet excitation of large water clusters (1994)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTVacuum ultraviolet excitation of large water clustersM. Ahmed, C. J. Apps, C. Hughes, and J. C. WhiteheadCite this: J. Phys. Chem. 1994, 98, 48, 12530–12534Publication Date (Print):December 1, 1994Publication History Published online1 May 2002Published inissue 1 December 1994https://pubs.acs.org/doi/10.1021/j100099a015https://doi.org/10.1021/j100099a015research-articleACS PublicationsRequest reuse permissionsArticle Views235Altmetric-Citations17LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
CANopen通信协议——标准化对于制造商、系统集成商和买家来说是一个有利条件 (2008)

多年来这种实时可用的CAN（控制器局域网）协议在汽车行业已经证明了它的物有所值。同时它的低成本和鲁棒性较强的物理层也使得这种协议对于工业网络具备吸引性。基于CAN协议的CANopen高层协议是特别针对工业嵌入式网络而开发出来的。
Effect of double vacuum bagging (DVB) in quickstep processing on the properties of 977‐2A carbon/epoxy composites (2013)

An aerospace grade prepreg 977‐2A carbon/epoxy composite was processed using traditional oven/autoclave and relatively new technique, Quickstep (QS). The manufacturer's recommended autoclave cure cycle was employed for oven/autoclave processing while due to greater flexibility to control the cure cycle temperature in order to manipulate the resin viscosity, several cure cycles were employed for Quickstep processing. Optimization methodology and effect of these cure schedules and their comparison with traditional oven/autoclave curing is presented in previously published article. However, in order to reduce the total cycle time of QS AD (QS‐60) cure schedule, an attempt was made to facilitate the excess resin to squeeze out during QS‐35 and QS‐45 cure. This attempt was based on the incorporation of double vacuum bagging (DVB) technique into Quickstep processing. Statistical analysis was performed to investigate any effect of DVB in Quickstep processing and it was observed that incorporation of DVB in Quickstep processing is not found to be significantly effective, however, it is believed that small resin rich patches of QS‐45 cured panels can be removed with controlled application of external pressure using DVB. POLYM. COMPOS., 34:942–952, 2013. © 2013 Society of Plastics Engineers
A P2P Network Based Architecture for Web Service (2007)

As a typical example of the SOA (service oriented architecture), Web service has been applied in e-business, e-government and many other fields as for its encapsulated, loosely coupled, dynamic binding, etc. mechanism. However, the mechanism of service publishing and discovery with centralized architecture, such as UDDI, restricts the reliability and scalability of the environment as the services and resources on the web are fast emerging. Using P2P technique is a good solution. This paper discusses an architecture of Web service publishing, discovery and invocation based on P2P, which makes the UDDI registry decentralized. Besides, a concept of WSB (Web service broker) is put forward to make the service invocation transparent between the two paradigms-Web service and P2P.
A Fuzzy Logic Controller for a Trafc Junction (1977)

Work done on the implementation of a fuzzy logic controller in a single intersection of two one-way streets is presented. The model of the intersection is described and validated, and the use of the theory of fuzzy sets in constructing a controller based on linguistic control instructions is introduced. The results obtained from the implementation of the fuzzy logic controller are tabulated against those corresponding to a conventional effective vehicle-actuated controller. With the performance criterion being the average delay of vehicles, it is shown that the use of a fuzzy logic controller results in a better performance.
A unified method for segmentation and edge detection using graph theory (2005)

Methods of image segmentation and edge detection based on graph theoretic representations of images are described. The image is mapped onto a weighted graph and, from this graph, spanning trees are used to describe regions and edges in the image. Edge detection is shown to be a dual problem to segmentation. Two methods are developed for both segmentation and edge detection, providing four related techniques. The simpler method uses the Shortest Spanning Tree (SST) to partition the graph and to form a segmentation or edge detection. The second method applies the first method recursively to incorporate global pictorial information into the graph, removing many problems of the simpler method and of other pixel-linking algorithms. An important property of the segmentation and edge detection methods is that image features may be described in a hierarchical way.
The shoot apical meristem: the dynamics of a stable structure (2002)

The shoot apical meristem (SAM) is a group of proliferating, embryonic-type cells that generates the aerial parts of the plant. SAMs are highly organized and stable structures that can function for years or even centuries. This is in apparent contradiction to the behaviour of their constituent cells, which continuously proliferate and differentiate. To reconcile the dynamic nature of the cells with the stability of the overall system the existence of elaborate signalling networks has been proposed. This is supported by recent work suggesting that the exchange of signals between cells, rather than a rigidly predetermined genetic program, is required for the establishment and functioning of an organized meristem. Together these interactions form a stable network, set up during embryogenesis, that assures the coordination of cell behaviour throughout development. Besides meristem-specific signalling cascades such as the CLAVATA receptor kinase pathway, which controls meristem size, these interactions involve plant hormones. In particular, cytokinins and auxins are implicated in the maintenance of meristem identity and phyllotaxis, respectively.
Time Course of Sleep-related Breathing Disorders in First-Ever Stroke or Transient Ischemic Attack (2000)

To investigate the prevalence and behavior of sleep-related breathing disorders (SRBDs) associated with a first-ever stroke or transient ischemic attack (TIA), we prospectively studied 161 consecutive patients admitted to our stroke unit. Complete neurological assessment was performed to determine parenchymatous and vascular localization of the neurological lesion. Stroke subtype was categorized as TIA, ischemic (IS), or hemorrhagic (HS). A portable respiratory recording (PRR) study was performed within 48-72 h after admission (acute phase), and subsequently after 3 mo (stable phase). During the acute phase, 116 patients (71.4%) had an apnea-hypopnea index (AHI) > 10 events/h and 45 (28%) had an AHI > 30. No relationships were found between sleep-related respiratory events and the topographical parenchymatous location of the neurological lesion or vascular involvement. Cheyne-Stokes breathing (CSB) was observed in 42 cases (26.1%). There were no significant differences in SRBD according to the stroke subtype except for the central apnea index (CAI). During the stable phase a second PRR was performed in 86 patients: 53 of 86 had an AHI > 10 and 17 of 86 had an AHI > 30. The AHI and CAI were significantly lower than those in the acute phase (16.9 +/- 13.8 versus 22.4 +/- 17.3 and 3.3 +/- 7.6 versus 6.2 +/- 10.2, respectively) (p < 0.05) while the obstructive apnea index (OAI) remained unchanged. CSB was observed in 6 of 86 patients. The prevalence of SRBD in patients with first-ever stroke or TIA is higher than expected from the available epidemiological data in our country. No correlation was found between neurological location and the presence or type of SRBD. Obstructive events seem to be a condition prior to the neurological disease whereas central events and CSB could be its consequence.
Molecular Characterization of a <i>Brucella</i> Species Large DNA Fragment Deleted in <i>Brucella abortus</i> Strains: Evidence for a Locus Involved in the Synthesis of a Polysaccharide (1999)

A Brucella melitensis 16M DNA fragment of 17,119 bp, which contains a large region deleted in B. abortus strains and DNA flanking one side of the deletion, has been characterized. In addition to the previously identified omp31 gene, 14 hypothetical genes have been identified in the B. melitensis fragment, most of them showing homology to genes involved in the synthesis of a polysaccharide. Considering that 10 of the 15 genes are missing in B. abortus and that all the polysaccharides described in the Brucella genus (lipopolysaccharide, native hapten, and polysaccharide B) have been detected in all the species, it seems likely that the genes described here might be part of a cluster for the synthesis of a novel Brucella polysaccharide. Several polysaccharides have been identified as important virulence factors, and the discovery of a novel polysaccharide in the brucellae which is probably not synthesized in B. abortus might be interesting for a better understanding of the pathogenicity and host preference differences observed between the Brucella species. However, the possibility that the genes described in this paper no longer encode the synthesis of a polysaccharide cannot be excluded. Brucellae belong to the alpha-2 subdivision of the class Proteobacteria, which includes other microorganisms living in association with eucaryotic cells, some of them synthesizing extracellular polysaccharides involved in the interaction with the host cell. The genes described in this paper might be a remnant of the common ancestor of the alpha-2 subdivision of the class Proteobacteria, and the brucellae might have lost such extracellular polysaccharide during evolution if it was not necessary for survival or for establishment of the infectious process. Nevertheless, further studies are necessary to identify the entire DNA fragment missing in B. abortus strains and to elucidate the mechanism responsible for such deletion, since only 9,948 bp of the deletion was present in the sequenced B. melitensis DNA fragment.