gebhart/patrepeval huggingface dataset:
Reconstruction of the proximal humerus after wide resection of tumours (2002)

In 45 patients we assessed the functional results and complications for three different reconstructive procedures after resection of primary tumors of the proximal humerus. An osteoarticular allograft was used in 11, a clavicula pro humero operation in 15 and a tumour prosthesis in 19. The glenoid was resected with the proximal humerus in 25 patients. The axillary nerve was resected in 42 patients. The complication rate was lowest after reconstruction with a tumour prosthesis. The clavicula pro humero operation resulted in the most revisions. Cumulative survival rates for all the reconstructive procedures were similar. At follow-up at two years the functional results for the three reconstructive procedures were the same with a mean functional rating of 79% (Musculoskeletal Tumor Society). Excision of the glenoid had no influence on the functional result. Our findings indicate that the use of a tumour prosthesis is the most reliable limb-salvage procedure for the proximal humerus. The clavicula pro humero is an appropriate procedure if a prosthesis cannot be used.
Synthese und Reaktionen von 6‐Hydroxyimino‐tetrahydro‐1,3,4‐thiadiazin‐2‐thionen (1973)

Abstract Aus aliphatischen Hydrazinen, Schwefelkohlenstoff und ω‐Nitrostyrolen werden die 6‐Hydroxyimino‐tetrahydro‐1,3,4‐thiadiazin‐2‐thione 7 und 15a – p hergestellt. Einige Reaktionen dieser neuen Verbindungsklasse werden beschrieben und die Spektren diskutiert.
A Dual Grain Hit-Miss Detector for Large Die-Stacked DRAM Caches (2013)

Die-Stacked DRAM caches offer the promise of improved performance and reduced energy by capturing a larger fraction of an application's working set than on-die SRAM caches. However, given that their latency is only 50% lower than that of main memory, DRAM caches considerably increase latency for misses. They also incur a significant energy overhead for remote lookups in snoop-based multi-socket systems. Ideally, it would be possible to detect in advance that a request will miss in the DRAM cache and thus selectively bypass it. This work proposes a “dual grain filter” which successfully predicts whether an access is a hit or a miss in most cases. Experimental results with commercial and scientific workloads show that a 158KB dual-grain filter can correctly predict data block residency for 85% of all accesses to a 256MB DRAM cache. As a result, average off-die latency with our filter is within 8% of that possible with a perfectly accurate filter, which is impractical to implement.
Insights into dolphin sonar discrimination capabilities from broadband sonar discrimination experiments with human subjects (1983)

A wide variety of dolphin sonar discrimination experiments have been conducted, yet little is known as to the cues utilized by dolphins in making fine target discriminations. Hammer and Au [J. Acoust. Soc. Am. 68, 1285–1293 (1980)] found a correlation between dolphin discrimination capabilities and the matched filter response of the target echoes. Sonar discrimination experiments have also been conducted with human subjects using the same targets employed in the Hammer and Au and other dolphin experiments. When digital recordings made of the target echoes ensonfied with a dolphinlike signal were played back at a slower rate to subjects, humans could make fine target discriminations under controlled laboratory conditions about as well as dolphins under less controlled conditions. Most of the cues reported by human subjects can be described by time-domain echo-features. The results of several dolphin sonar and human listening experiments will be discussed along with the target echo characteristics.
Gas Turbine Inlet Air Filtration in Marine Environments: Part I — Marine Aerosols and Equipment for Their Control (1980)

The chief mechanisms by which salt is introduced into marine air are examined, and the quantity and character of the salt are related to environmental conditions, height above the sea, and distance inland from the shore. Characteristics of commercially available moisture separators are described, and statistical descriptions of salt levels are calculated for representative applications.
Flow and changes in appearance (1996)

An important, largely unexplored area of computer image generation is the simulation of weathering and its effects on appearance. Weathering results from the interaction of the environment with the materials in the world. The flow of water is one of the most pervasive and important natural forces involved in the weathering of materials, producing a distinctive set of patterns of washes and stains. This paper presents an intuitive phenomenological model for the flow of water over surfaces that is capable of generating such changes in appearance.
High Speed Signal Transmission using Through-Si Vias and Coplanar Waveguides in a 3D IC Test Structure (2013)

High frequency signal transmission through silicon substrates is critical for 3D heterogeneous integration. This paper presented fabrication, testing, and simulation of high-frequency interconnects based on through-silicon vias (TSVs) and coplanar waveguides (CPWs) for stacked 3D integrated circuits (3D ICs). Our simulation results showed that adding ground TSVs can improve signal transmission by 6× at 50GHz. We further investigated signal/ground TSV (1SXG) configurations for high-bandwidth signal transmission links. Scattering parameter measurements of fabricated 1SXG TSV structures for frequencies from 100MHz to 50GHz show low insertion loss (S21 less than −1dB up to 50GHz) and return loss (S11 lower than −15dB). These results indicate that these vertical interconnects exhibit good performance for high speed signal transmission. To understand the RF signal transmission in 3D interconnects, we used full wave electromagnetic simulation to investigate the electromagnetic field distribution associated with the ground TSV placement. We observed that the ground TSVs induced substantial overall field confinement, consistent with the experimental observation of improved signal transmission. Simulations also provided design guidance with respect to the substrate conductivity's impact on EM confinement and signal transmission.
Analysis of Human Cytomegalovirus-Encoded MicroRNA Activity during Infection (2009)

MicroRNAs (miRNAs) are expressed in a wide variety of organisms, ranging from plants to animals, and are key posttranscriptional regulators of gene expression. Virally encoded miRNAs are unique in that they could potentially target both viral and host genes. Indeed, we have previously demonstrated that a human cytomegalovirus (HCMV)-encoded miRNA, miR-UL112, downregulates the expression of a host immune gene, MICB. Remarkably, it was shown that the same miRNA also downregulates immediate-early viral genes and that its ectopic expression resulted in reduced viral replication and viral titers. The targets for most of the viral miRNAs, and hence their functions, are still unknown. Here we demonstrate that miR-UL112 also targets the UL114 gene, and we present evidence that the reduction of UL114 by miR-UL112 reduces its activity as uracil DNA glycosylase but only minimally affects virus growth. In addition, we show that two additional HCMV-encoded miRNAs, miR-US25-1 and miR-US25-2, reduce the viral replication and DNA synthesis not only of HCMV but also of other viruses, suggesting that these two miRNAs target cellular genes that are essential for virus growth. Thus, we suggest that in addition to miR-UL112, two additional HCMV miRNAs control the life cycle of the virus.
Light metal hydrides and superconductivity (1991)

We have investigated theoretically the electronic properties of a number of light metal hydrides, a class of materials which have been recently proposed as a good candidate for high temperature superconductivity. An attempt has also been made to synthesize some of the relevant chemical precursors of such compounds with the idea of preparing pure samples suitable for physical analysis. In this report we describe the methods and the results of a systematic study of the electronic band structure of a number of selected light metal hydrides. The theoretical technique employed is a self consistent procedure based on the linear augmented plane wave method and the local density approximation. We have performed calculations for the cases of LiH, LiBeH{sub 3} and LiMgH{sub 3}. The latter had not been previously studied. We find that when the divalent ions, (Be or Mg), are located at the cube centers of a direct perovskite structure, both LiBeH{sub 3} and LiMgH{sub 3} behave as semiconductors. On the other hand when the Li atoms are located at the cubic centers of the corresponding inverted perovskites the two materials display an interesting metallic character. The effects on the band structure of hydrostatic pressure is also briefly discussed. Ourmore » findings indicate that it is conceivable that suitable light metal hydrides can be found which will display metallic properties and ultimately superconductivity. The need for reliable methods for the synthesis of these compounds has yet to be satisfied and presents a challenge for the future. 37 refs., 13 figs., 1 tab.« less
Activation of Fc receptor-bearing lymphocytes by immune complexes. II. Killer lymphocytes mediate Fc ligand-induced lymphokine production. (1981)

Cells that participate in immune complex-induced production of leukocyte migration inhibitory factor (LIF) activity can be concentrated in a population making up 2-4% of human peripheral blood lymphocytes in which greater than 90% of the cells are active in a single cell antibody-dependent cellular cytotoxicity assay. When so concentrated, such killer (K) cell preparations are as efficient in producing LIF activity as mitogen activated T lymphocytes. Other Fc receptor (FcR)-bearing lymphocytes, including natural killer (NK) cells, do not produce measurable LIF activity when incubated with immune complexes (additional evidence that the K and NK cells among ligands to the FcR of the appropriate lymphocytes, possibly without need for exogenous receptor bridging, is the only requirement for their activation to immune complex-induced lymphokine production (ICLP). It is probable that ICLP by K cells palays a role in antibody-mediated effector functions in vivo.
Luminescence decay of ruthenium(II) complexes adsorbed on metal oxide powders in vacuo: energy gap dependence of the electron-transfer rate (1988)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTLuminescence decay of ruthenium(II) complexes adsorbed on metal oxide powders in vacuo: energy gap dependence of the electron-transfer rateK. Hashimoto, M. Hiramoto, A. B. P. Lever, and T. SakataCite this: J. Phys. Chem. 1988, 92, 5, 1016–1018Publication Date (Print):March 1, 1988Publication History Published online1 May 2002Published inissue 1 March 1988https://pubs.acs.org/doi/10.1021/j100316a005https://doi.org/10.1021/j100316a005research-articleACS PublicationsRequest reuse permissionsArticle Views194Altmetric-Citations61LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Hypothalamic-Pituitary Functions in Patients with Idiopathic Pituitary Dwarfism (1975)

To investigate hypothalamic-pituitary functions and the primary site of the lesion in idiopathic pituitary dwarfism, various pituitary function tests, especially the pituitary hormone responses to the hypophysiotropic hormones were studied in 23 patients with idiopathic pituitary dwarfism. A few cases showed slight responses of GH to GH stimulation tests. Gonadotropin deficiencies were most frequently noted among pituitary hormones. The basal levels and the responses of plasma LH and FSH to LH-RH test were diminished markedly in all of the cases except in 5 cases with isolated GH deficiency. Responses of LH and FSH to LH-RH improved markedly after a long term administration of LH-RH for a period of one month in 2 patients with gonadotropin deficiency. As to TSH axis, half of the cases accompanied hypothyroidism. However, the responses of TSH to TRH were normal in all of the cases regardless of the thyroid function. The basal levels and the responses of plasma cortisol and 11-deoxycortisol to the rapid metopirone test were also impaired in about half of the cases. Basal levels of plasma prolactin were normal in all of the cases and the responses of prolactin to TRH were normal in cases with normal thyroid function, but slightly delayed in cases with hypothyroidism. It is concluded from the above observations that the incidences of various pituitary hormone deficiencies were quite high in this disorder and hypophysiotropic hormone deficiencies may cause pituitary hormone deficiencies. Therefore, it is suggested that the primary site of the lesion in this disorder might be at the hypothalamus.
Rapid Photorealistic Blendshape Modeling from RGB-D Sensors (2016)

Creating and animating realistic 3D human faces is an important element of virtual reality, video games, and other areas that involve interactive 3D graphics. In this paper, we propose a system to generate photorealistic 3D blendshape-based face models automatically using only a single consumer RGB-D sensor. The capture and processing requires no artistic expertise to operate, takes 15 seconds to capture and generate a single facial expression, and approximately 1 minute of processing time per expression to transform it into a blendshape model. Our main contributions include a complete end-to-end pipeline for capturing and generating photorealistic blendshape models automatically and a registration method that solves dense correspondences between two face scans by utilizing facial landmarks detection and optical flows. We demonstrate the effectiveness of the proposed method by capturing different human subjects with a variety of sensors and puppeteering their 3D faces with real-time facial performance retargeting. The rapid nature of our method allows for just-in-time construction of a digital face. To that end, we also integrated our pipeline with a virtual reality facial performance capture system that allows dynamic embodiment of the generated faces despite partial occlusion of the user's real face by the head-mounted display.
Predictable crestal bone remodelling around two porous‐coated titanium alloy dental implant designs. A radiographic study in dogs. (1994)

We have previously suggested that altering the height of the porous-coat segment of a partially porous-coated TiAl6V4 endosseous dental implant would affect the degree of crestal bone loss occurring during implant function by changing the patterns of stress transfer. This conclusion arose from the analysis of data from several different experiments and lacked a direct intra-animal comparison. In the present study we have compared two implant designs varying only in the extent to which they were porous-coated. With one design (type A) the coronal 1.8 mm of the implant root had a machined surface while the remainder of its length was porous-coated with TiAl6V4 beads. The other design (type B) had all but the coronal-most 0.75 mm porous-coated. Two implants of each type were placed in each of 4 dogs and the sites allowed to heal for 4 weeks before re-entry and prosthesis attachment. Monthly the implant-supported bridges were removed and radiographs exposed of each implant using a special film holder connected separately to each implant. These radiographs were analyzed for crestal bone loss using both direct visual and computer-assisted techniques. The results showed that bone remodelled to the machined surface-to-porous coat junction for type B implants and achieved a steady state by 12 weeks of function, whereas a longer time was required to achieve this state with type A implants. Significantly more bone loss occurred with the type A design, and this difference was detectable as early as after the first month of function.
Comparison of Generic to Disease-Specific Quality-of-Life Measures in Patients With Irritable Bowel Syndrome (2014)

Introduction: IBS is one of the most common illnesses gastroenterologists (GEs) encounter. Because it lacks a reliable biomarker, treatment goals emphasize optimizing quality of life (QOL) which in patients seen in tertiary care clinics is significantly impaired (Lackner et al., 2006). Current guidelines suggest routine assessment of QOL in all patients, and recommend initiating treatment when QOL is found to be diminished (ACG, 2009). While a number of QOL measures have been used with IBS patients, their focus and intent differ. Generic measures (e.g., SF-12) yield a global QOL index designed to compare the health status of IBS patients to those with other medical conditions. Disease-specific measures (e.g., IBS-QOL), on the other hand, assess the specific physical and emotional limitations associated with IBS. Comparison studies of the psychometric value of generic and disease specific measures are needed to assess their potential clinical utility (Patrick and Deyo, 1989). Aim: To document the relative magnitude of associations between health outcomes important to IBS and different QOL measures used for IBS patients. Methods: As part of pre-treatment baseline assessment of an NIH trial, 283 Rome III diagnosed IBS patients (F, 80%; M age=41) without comorbid GI disease completed the SF-12, Irritable Bowel Syndrome QOL (IBSQOL), IBS Symptom Severity Scale (IBS-SSS), Brief Symptom Inventory (BSI, distress), abdominal pain intensity scale, IBS Health Care Use Inventory, and SOMS-7 (somatization). Results: The physical well being scale of the SF-12 (PCS SF12) and IBSQOL were significantly associated with somatization, distress, IBS-SSS, abdominal pain, and frequency of health care use (p’s <0.05). In most cases, the strength of the associations was not statistically different between the 2 QOL measures. The strength of the association between the SF-12 PCS and health care use (r=-0.27) was significantly greater than with IBSQOL (r = -0.15, p <0.05). The magnitude of the relationship between the IBSQOL and BSI was significantly greater (r=-0.47) than with PCS SF-12 (r=-0.32). However, the differences in the associations between BSI and both IBSQOL and mental wellbeing scale of the SF-12 (MCS SF-12) were statistically nonsignificant (rs=0.47 vs. 0.55). Conclusion: Generally speaking, both the IBSQOL and SF-12 PCS are so similarly correlated with health outcomes that their joint administration is unlikely to yield incremental value for GEs in busy clinical settings. If GEs plan to adopt a single measure for gauging QOL practices where multiple GI disorders are treated, the SF-12 would be an appropriate measure although it may underestimate to some extent the magnitude of illness burden (i.e., IBS symptom severity, distress). Support: NIH Grant # DK77738.
Let-7i-5p represses brite adipocyte function in mice and humans (2016)

In response to cold or β3-adrenoreceptor stimulation brown adipose tissue (BAT) promotes non-shivering thermogenesis, leading to energy dissipation. BAT has long been thought to be absent or scarce in adult humans. The recent discovery of thermogenic brite/beige adipocytes has opened the way to development of novel innovative strategies to combat overweight/obesity and associated diseases. Thus it is of great interest to identify regulatory factors that govern the brite adipogenic program. Here, we carried out global microRNA (miRNA) expression profiling on human adipocytes to identify miRNAs that are regulated upon the conversion from white to brite adipocytes. Among the miRNAs that were differentially expressed, we found that Let-7i-5p was down regulated in brite adipocytes. A detailed analysis of the Let-7i-5p levels showed an inverse expression of UCP1 in murine and human brite adipocytes both in vivo and in vitro. Functional studies with Let-7i-5p mimic in human brite adipocytes in vitro revealed a decrease in the expression of UCP1 and in the oxygen consumption rate. Moreover, the Let-7i-5p mimic when injected into murine sub-cutaneous white adipose tissue inhibited partially β3-adrenergic activation of the browning process. These results suggest that the miRNAs Let-7i-5p participates in the recruitment and the function of brite adipocytes.
Stability of Carotene and Vitamin A in Dry Mixtures (1951)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTStability of Carotene and Vitamin A in Dry MixturesMonroe E. Wall and Edward G. KelleyCite this: Ind. Eng. Chem. 1951, 43, 5, 1146–1150Publication Date (Print):May 1, 1951Publication History Published online1 May 2002Published inissue 1 May 1951https://pubs.acs.org/doi/10.1021/ie50497a043https://doi.org/10.1021/ie50497a043research-articleACS PublicationsRequest reuse permissionsArticle Views40Altmetric-Citations5LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Microsuspension Polymerization of Vinyl Chloride / Mikrosuspensionspolymerisation von Vinylchloridi (1987)

Article Microsuspension Polymerization of Vinyl Chloride / Mikrosuspensionspolymerisation von Vinylchloridi was published on July 1, 1987 in the journal Tenside Surfactants Detergents (volume 24, issue 4).
Multimedia Broadcast/Multicast Service (MBMS) (2008)

This chapter contains sections titled: MBMS Overview MBMS Architecture MBMS Services Performance of MBMS References
<title>Iterative correction of holographic lenses</title> (1994)

Holographic optical lens elements (HOEs) are volume grating in thick material such as dichromated gelatine (DCG) which suffer from the wavelength mismatch between the recording process and the practical application e.g., at laser diode wavelengths. Wavelength mismatch between recording and reconstruction is caused by the fact that the best recording materials are sensitive only in the blue region of the spectrum. The advantage of volume gratings (thickness 13 micrometers ) is the large angle of deflection of the first diffraction order with a high diffraction efficiency. An optimized recording geometry using only spherical wave fronts allows on the one hand for the elimination of one of the third order aberrations (predominantly: astigmatism) or on the other hand for the fulfillment of the Bragg condition. To optimize the properties of holographic optical lens elements with one aspheric recording wave a kind of iterative procedure for the manufacturing is proposed. Each iteration consists of three different steps.