gebhart/patrepeval huggingface dataset:
Personal digital assistants as cognitive aids for high school students with autism: Results of a community-based trial (2010)

Objective: The purpose of this study was to examine the efficacy of personal digital assistants (PDAs) as task management tools in a sample of transition-age high school students with autism. Method: The group included twenty-two high school students selected from locales across the Commonwealth of Virginia, all of whom carry a diagnosis of autism and exhibit difficulties in performing everyday tasks due to cognitive-behavioral problems. Participants were trained by an occupational therapist to use PDAs as task management tools and participants and their parents completed self-assessments of occupational performance (using the Canadian Occupational Performance Measure (COPM)) before training and eight weeks after training concluded. At the post-assessment, PDAs were examined for recorded appointments and other entries, as evidence of participants’ usage, and participants were asked to demonstrate programming the PDA for reminder alarms and other functions, as a measure of their retention of training. Results: Eight weeks after completion of training, the group demonstrated statistically significant improvement on COPM occupational performance and satisfaction with occupational performance scores, all PDA calendars showed reminder alarms scheduled for each day of the week across the eight week post-training period and all participants demonstrated the ability to respond to reminder alarms appropriately. Also, eight weeks after training, most participants (18 of 22 or 82%) were able to program device software, as trained, demonstrating retention of training and suggesting everyday use of the device. All participants attested to everyday device use and said that the device had improved their independence in performing functional activities. Conclusion: A brief training intervention utilizing PDAs as cognitive aids is associated with improved self-ratings of performance and satisfaction in everyday life tasks among a group of high school students with autism. This group also demonstrated retention of training when reassessed eight weeks later, and their devices showed calendar entries across the eight weeks that suggest everyday use.
The MYC-Associated Protein CDCA7 Is Phosphorylated by AKT To Regulate MYC-Dependent Apoptosis and Transformation (2012)

Cell division control protein A7 (CDCA7) is a recently identified target of MYC-dependent transcriptional regulation. We have discovered that CDCA7 associates with MYC and that this association is modulated in a phosphorylation-dependent manner. The prosurvival kinase AKT phosphorylates CDCA7 at threonine 163, promoting binding to 14-3-3, dissociation from MYC, and sequestration to the cytoplasm. Upon serum withdrawal, induction of CDCA7 expression in the presence of MYC sensitized cells to apoptosis, whereas CDCA7 knockdown reduced MYC-dependent apoptosis. The transformation of fibroblasts by MYC was reduced by coexpression of CDCA7, while the non-MYC-interacting protein Δ(156-187)-CDCA7 largely inhibited MYC-induced transformation. These studies provide insight into a new mechanism by which AKT signaling to CDCA7 could alter MYC-dependent growth and transformation, contributing to tumorigenesis.
A new user similarity model to improve the accuracy of collaborative filtering (2013)

Collaborative filtering has become one of the most used approaches to provide personalized services for users. The key of this approach is to find similar users or items using user-item rating matrix so that the system can show recommendations for users. However, most approaches related to this approach are based on similarity algorithms, such as cosine, Pearson correlation coefficient, and mean squared difference. These methods are not much effective, especially in the cold user conditions. This paper presents a new user similarity model to improve the recommendation performance when only few ratings are available to calculate the similarities for each user. The model not only considers the local context information of user ratings, but also the global preference of user behavior. Experiments on three real data sets are implemented and compared with many state-of-the-art similarity measures. The results show the superiority of the new similarity model in recommended performance.
Substituent effects on the reactivity of triarylimidazolyl free radicals toward tris(2-methyl-4-diethylaminophenyl) methane (1971)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSubstituent effects on the reactivity of triarylimidazolyl free radicals toward tris(2-methyl-4-diethylaminophenyl) methaneRobert L. CohenCite this: J. Org. Chem. 1971, 36, 16, 2280–2284Publication Date (Print):August 1, 1971Publication History Published online1 May 2002Published inissue 1 August 1971https://pubs.acs.org/doi/10.1021/jo00815a018https://doi.org/10.1021/jo00815a018research-articleACS PublicationsRequest reuse permissionsArticle Views379Altmetric-Citations39LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Analysis of the cyclic short-term variation of indoor power line channels (2006)

The purpose of this paper is to analyze the properties of indoor power line communications channels when they are used for broadband transmission. It will be shown that these channels exhibit a short-term variation, due to the fact that high-frequency parameters of electrical devices depend on the instantaneous amplitude of mains voltage. This phenomenon leads to a channel model proposal based on a linear periodically time-varying system and cyclostationary random noise. A measurement system, designed to capture these time variations in real power networks, and some of the most significant results obtained with it, are presented. In addition, a statistical analysis of the measurements performed in several indoor power line scenarios is included, so that the relevance of time variations in actual channels can be evaluated.
Caloric restriction augments brain glutamic acid decarboxylase‐65 and ‐67 expression (2004)

The ketogenic diet is a very low-carbohydrate, high-fat diet used to treat refractory epilepsy. We hypothesized that this diet may act by increasing expression of glutamic acid decarboxylase (GAD), the rate-limiting enzyme in gamma-aminobutyric acid (GABA) synthesis. Thus, we evaluated brain GAD levels in a well-established, seizure-suppressing, rodent model of the ketogenic diet. Because the diet is most effective when administered with a modest ( approximately 10%) calorie restriction, we studied three groups of animals: rats fed ad libitum standard rat chow (Ad lib-Std); calorie-restricted standard chow (CR-Std); and an isocaloric, calorie-restricted ketogenic diet (CR-Ket). We found that GAD67 mRNA was significantly increased in the inferior and superior colliculi and cerebellar cortex in both CR diet groups compared with control (e.g., by 45% in the superior colliculus and by 71% in the cerebellar cortex; P <.001). GAD65 mRNA was selectively increased in the superior colliculus and temporal cortex in both CR-Std and CR-Ket diet groups compared with ad lib controls. The only apparent CR-Ket-specific effect was a 30% increase in GAD67 mRNA in the striatum (P =.03). Enhanced GAD immunoreactivity was detected in parallel with the mRNA changes. These data clearly show that calorie restriction increases brain GAD65 and -67 expression in several brain regions, independent of ketogenic effects. These observations may explain why caloric restriction improves the efficacy of the ketogenic diet in treating epilepsy and suggest that diet modification might be useful in treatment of a number of brain disorders characterized by impaired GAD or GABA activity.
[The toxicity variation of organic extracts in drinking water treatment processes]. (2001)

Source water samples and outlet water samples from different treatment processes of the Beijing Ninth Water Works were concentrated in situ with XAD-2 filled columns. GC-MS analysis and toxic assessment including acute toxicity evaluation by luminescent bacterium bioassay(Q67 strains) and mutagenicity assessment by Ames test(TA98 and TA100 strains with and without S9 addition) were conducted on these samples. The results showed that prechlorination caused the direct and indirect frame shift mutagenicity as well as indirect base pair substitute mutagenicity. Addition of coagulant may increase the base pair substitute mutagenic effects greatly. Sand and coal filtration and granular activated carbon filtration could effectively remove most of the formed mutagens. The rechlorination do not obviously increase the mutagenic effects. No mutagenic effect was observed in tap water. Acute toxicity showed the same variation with that of mutagenicity during the treatment processes. Sample from flocculation treatment process was found to be the most toxic sample. Results of GC-MS analysis showed that water in this plant was not contaminated by PCB. Concentrations of toluene, naphthalene and phenol increased in flocculation treatment process and in tap water. However, the concentrations of these substances were at the level of microgram/L, therefore, were not high enough to cause mutagenicity.
VLSI architecture for low power motion estimation using high data access reuse (2003)

This paper presents a new VLSI architecture of the motion estimation in MPEG-2. Previously various full search block matching algorithms (BMA) and architectures using systolic array have been proposed for motion estimation. However, the architectures have inefficiently a large number of external memory access. Our new architecture efficiently reuses data to decrease external memory accesses and saves the computational time by using a parallel algorithm.
Cholesteric states of micellar solutions (1978)

The effects of optically active compounds on amphiphilic nematics are reported. The following systems have been studied : (1) caesium decylsulphate, decanol, water plus tartaric acid ; (2) ammonium decylsulphate, ammonium sulphate, decanol, water plus brucine sulphate ; and (3) decylammonium chloride, water plus cholesterol. Phase transitions to cholesteric states are induced by the optically active compounds in all systems. Brucine sulphate has the highest twisting power ; tartaric acid the lowest. The results are analysed on the basis of intermolecular interactions and an explanation is proposed for the observed differences in twisting power.
Stimulated Maximum Likelihood Estimation of Continuous Time Stochastic Volatility Models (2009)

In this paper we develop and implement a method for maximum simulated likelihood estimation of the continuous time stochastic volatility model with the constant elasticity of volatility. The approach do not require observations on option prices nor volatility. To integrate out latent volatility from the joint density of return and volatility, a modified efficient importance sampling technique is used after the continuous time model is approximated using the Euler-Maruyama scheme. The Monte Carlo studies show that the method works well and the empirical applications illustrate usefulness of the method. Empirical results provide strong evidence against the Heston model.
Streptomyces somaliensis mediated green synthesis of silver nanoparticles (2015)

Objective(s): The development of reliable and ecofriendly process for the synthesis of nano-metals is an important aspect in the field of nanotechnology. Nano-metals are a special group of materials with broad area of applications. Materials and Methods: In this study, extracellular synthesis of silver nanoparticles (SNPs) performed by use of the gram positive soil Streptomycetes. Streptomycetes isolated from rice fields of Guilan Province, Iran (5 isolates). Initial characterization of SNPs was performed by visual change color. To determine the bacterium taxonomical identity, its colonies characterized morphologically by use of scanning electron microscope. The PCR molecular analysis of active isolate represented its identity partially. In this regard, 16S rDNA of isolate G was amplified using universal bacterial primers FD1 and RP2. The PCR products were purified and sequenced. Sequence analysis of 16S rDNA was then conducted using NCBI GenBank database using BLAST. Also SNPs were characterized by, transmission electron microscopy (TEM) and X-ray diffraction spectroscopy (XRD). Results: From all 5 collected Streptomyces somaliensis isolates, isolate G showed highest extracellular synthesis of SNPs via in vitro. SNPs were formed immediately by the addition of (AgNO3) solution (1 mM). UV-visible spectrophotometry for measuring surface plasmon resonance showed a single absorption peak at 450 nm, which confirmed the presence of SNPs. TEM revealed the extracellular formation of spherical silver nanoparticles in the size range of 5-35 nm. Conclusions: The biological approach for the synthesis of metal nanoparticles offers an environmentally benign alternative to the traditional chemical and physical synthesis methods. So, a simple, environmentally friendly and cost-effective method has been developed to synthesize AgNPs using Streptomycetes.
After-Heater Furnace for Verneuil Crystal Growing Technique (1965)

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Ancient cultures and migration to the Americas (2005)

Back in the old days, say about three years ago, we had a pretty compelling scenario for the peopling of the Americas. We believed the first Americans came out of northeast Asia during the latest Pleistocene, crossing the Bering land bridge into Alaska during a period of lowered sea level. For a time the massive North American ice sheets blocked their way south, but after the Laurentide and Cordilleran glaciers melted, back say 12,000 years ago, a group or groups of these hunters sped south through the newly opened "Ice-Free" Corridor between them (Wright, 1991). Once they reached the unglaciated lower 48 states, they radiated out across the length and breadth of North America with what appears to be archaeologically breathtaking speed (e.g. Haynes, 1964, 1992).(Meltzer (2001: 27))
Effects of streptozotocin treatment in growth hormone (GH) and GH antagonist transgenic mice (1995)

To investigate GH's role in diabetic end organ damage, experimental diabetes was induced with streptozotocin (STZ) in bovine GH (bGH) or bGH antagonist transgenic mice and in their nontransgenic (NTG) litter mates. Body growth, blood glucose, serum insulin-like growth factor-I levels, liver GH receptor (GHR) binding, and kidney histology of these animals were evaluated. After administration of multiple low doses of STZ, 90% of the mice developed hyperglycemia. The diabetic animals, especially those expressing GH and GH antagonist transgenes, demonstrated retarded body growth and reduced insulin-like growth factor-I levels when compared with their nondiabetic litter mates. Kidney histology revealed severe glomerulosclerosis in diabetic and nondiabetic bGH transgenic mice. Diabetic NTG mice exhibited moderate kidney lesions. Diabetic bGH antagonist transgenic mice possessed normal glomeruli indistinguishable from those seen in nondiabetic NTG mice. GHR-binding assays revealed that liver GHR-binding sites were significantly reduced in diabetic NTG mice and transgenic dwarf mice when compared with their nondiabetic controls. Conversely, liver GHR-binding ability was significantly increased in bGH transgenic mice as compared with their NTG littermates and remained high during diabetes. It is concluded that transgenic mice that express a GH antagonist are protected from diabetes and or GH-induced nephropathy.
Channel estimation and compensation for preamble-assisted DAPSK transmission in digital mobile radio system (2001)

This paper presents a novel channel estimation and compensation technique, combining fading estimation and frequency offset estimation, for preamble-assisted differentially encoded amplitude- and phase-shift keying (DAPSK) transmission in a digital mobile radio system. The received preamble symbols are used to estimate the combined distortions caused by multipath fading and frequency offset. The detected data symbols as well as preamble symbols are used to enhance the accuracy of the estimation process. The combined distortions can be compensated in the data symbols at the same time. The storage-delay time of the estimation process is only several symbols long. A series of computer simulations have been carried out to investigate the bit error rate performance of the preamble-assisted 16-DAPSK signals with uncertain frequency offset in the frequency-nonselective and frequency-selective Rayleigh fading channels.
Human machine interactions with future flight deck and air traffic control systems (2017)

The attainable accuracy and dependency of modern aircraft is quite superior to that of older technologies, but solving one problem often creates new and unexpected flaws in the modified or new design. Time pressure can hurry the crews and increase the likelihood of human errors when ‘instructing’ the aircraft. The modern aircraft clearly are less noisy and technologies are still improving, so a main problem will be to accommodate the traffic as the absolute number of flights will increase. The progression in air traffic control is generally considered to have fallen behind the state of the art of modern aircraft and major improvements are needed. Datalink communication can involve computer-computer interfacing as well as air-ground human operator communications. Pilot can request route changes, ask for information etc. while the controller can detect possible conflicts in the future and provide the aircraft with instructions.
UNISPACER ARTHROPLASTY OF THE KNEE (2005)

Background: The operative treatment of medial compartment knee arthritis is controversial. The purpose of the present study was to report the experience of a single surgeon with the UniSpacer arthroplasty for the treatment of isolated medial compartment arthritis of the knee. Methods: From April 2002 through November 2002, thirty-seven UniSpacer arthroplasties were performed in thirty-four patients for the treatment of arthritis that primarily involved the medial compartment of the knee. The Ahlbäck radiographic evaluation scale was used to grade the severity of arthritis; the mean preoperative score was 2.6 points for the medial compartment and 0.5 point for both the lateral and patellofemoral compartments. The study group included eighteen women (nineteen knees) and sixteen men (eighteen knees) who had a mean age of fifty-five years (range, forty-two to seventy-five years) at the time of surgery. Twelve patients had had a previous arthroscopic meniscectomy. The mean preoperative Knee Society function score was 60 points (range, 40 to 80 points), and the mean preoperative Knee Society objective score was 62 points (range, 40 to 76 points). Results: After a mean duration of follow-up of twenty-six months (range, twenty-four to twenty-nine months), there were no excellent, ten good, fifteen fair, and twelve poor results. The mean postoperative total function score was 69 points (range, 40 to 82 points), and the mean Knee Society objective score was 72 points (range, 45 to 88 points). Six of the twelve poor results were in knees that had dislocation of the UniSpacer. All twelve knees were revised to a total knee arthroplasty. Conclusions: On the basis of this experience, we do not recommend UniSpacer arthroplasty for the treatment of degenerative arthritis of the medial compartment of the knee. Level of Evidence: Therapeutic Level IV. See Instructions to Authors for a complete description of levels of evidence.
Aggregation and deposition of engineered TiO<sub>2</sub>nanoparticles in natural fresh and brackish waters (2011)

The use and thus environmental release potential of metal-based nanoparticles have rapidly increased. Due to their size-dependent new properties, the fate and effect of nanomaterial may differ from those of the conventional form of corresponding material. The agglomeration and sedimentation were studied by spiking the TiO2-P25 particles in natural fresh and brackish water samples. The natural waters were determined for conductivity, pH, salinity, total organic carbon, turbidity, common nutrients and trace elements. The hydrodynamic diameter and concentration of TiO2-P25 particle dispersions were monitored by using a dynamic light scattering and a spectrophotometer, respectively. The experiments were performed at two particle concentrations 100 mg/l and 1 mg/l (10 mg/l for deposition studies). The aggregation rates in brackish waters were clearly higher in higher initial concentration and the sedimentation of aggregates decreased the TiO2 concentration down to 20% and 80% of initial higher and lower concentrations, respectively. One fresh water sample favoured the destabilisation of TiO2-P25 particles whereas another fresh water sample stabilised the TiO2 particle dispersion. The aggregation had a strong dependence on the particle concentration. High ionic content of brackish water probably explains the formation of aggregates, whereas organic substances and pH may account for the different agglomeration behaviour in fresh waters.
Time, space and the commodity-form (2010)

Consumer Culture Reborn focuses on consumption as the point at which economy and culture combine. The book draws the often polarised discourses of political economy and cultural studies closer together in a historical context as a means of understanding our social situations as we approach the end of the millenium. Taking as its central theme the ability of the capitalist mode of production to transform the material and social world which sustains it, the book focuses on some of the ways in which this transformational impulse has altered the means by which ordinary people reproduce their life and their patterns of life. Neither a history book, nor simply a book of theory, Consumer Culture Reborn fuses elements of economic, social and cultural theory in an historical perspective.
Combination of Geomechanical Modelling and Tomography to Resolve Severe Velocity Variations Below Rugose Seafloor (2012)

Seismic imaging and depth-velocity modelling below a seafloor with complex topography are always challenging. The problems are caused by two types of lateral velocity variations: (1) contrast between the water and sediments and (2) velocity variations within shallow sediments created by the variable water depth. Geomechanical effects contribute to velocity variations in shallow sediments. Variable water depth always creates some variations in overburden pressure and variable pressure changes seismic velocities. We propose a new version of tomographic inversion that is focused (constrained) to recover these types of geomechanical (compaction driven) velocity anomalies associated with rugose seafloor. Applied together with geomechanical modelling and standard seismic tomography it helps to solve the strongest and most complicated water bottom related velocity anomalies. Synthetic and real data examples illustrate how this combination works.