gebhart/patrepeval huggingface dataset:
Analysis of the role of Y1494 in α6β4 integrin-mediated breast carcinoma progression. (2007)

AACR Annual Meeting-- Apr 14-18, 2007; Los Angeles, CA

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The α6β4 integrin is a cell surface adhesion receptor for the laminin family of extracellular matrix proteins and has been implicated in promoting tumor progression and metastasis. Although some progress has been made in understanding how the α6β4 integrin contributes to carcinoma progression, we still know relatively little about the mechanisms by which this integrin receptor regulates tumor cell invasion and survival. We previously identified a tyrosine residue, Y1494, in the β4 cytoplasmic domain that is required for the ability of the α6β4 integrin to promote breast carcinoma cell invasion and survival. To examine further the contribution of Y1494 to tumor progression, we examined MDA-MB-435 breast carcinoma cells expressing either wildtype-β4 or Y1494F mutant-β4 for their ability to form colonies in both soft agar and Matrigel. Cells expressing the wildtype-β4 subunit formed colonies of a similar size and number in soft agar when compared with MDA-MB-435 cells that had been transfected with vector alone. In contrast, cells expressing the mutant Y1494F-β4 subunit were significantly impaired in their ability to grow in soft agar assays. Although all of the cell lines grew as colonies in Matrigel, only cells expressing the wildtype-β4 subunit were invasive. Taken together, these results suggest a vital role for Y1494 in α6β4-mediated anchorage independent growth and invasion. To assess the impact of Y1494 on tumor growth and metastasis, cells expressing wildtype and Y1494F mutant β4 were injected orthotopically into the mammary fat pad of immuno-compromised mice. All of the mice injected with cells expressing either vector or wildtype-β4 developed tumors. However, only 10% of the mice injected with cells expressing the Y1494F mutant-β4 subunit developed tumors. We are currently investigating the mechanism by which Y1494 positively contributes to the function of the α6β4 integrin. Our preliminary results reveal a role for Y1494 in the α6β4-dependent activation of the Erk1/2 MAPKs. (Supported by Susan G. Komen Foundation and the American Cancer Society)
Studies on Flavorous Substances in Soy (1953)

The flavorous substances in the first steam distillate of Soy-cake, of which the boiling point is below 75°, were studied, and some mercaptane and its mercaptal were identified, besides acetaldehyde, propionaldehyde, n- and isobutyraldehyde and is oval eraldehyde. According to the elementary analysis of continued distillate, d. p. of Hg-salt and color-re actions, those S-compounds are supposed to be methylmercaptane and isobutyraldehyde dimethylmercaptal or allylmercaptane.
Effect of Hot-band Annealing Condition on Secondary Recrystallization in Grain-oriented 2.3%Si-1.7%Mn Steel. (2000)

The effect of hot-band annealing temperature on secondary recrystallization was investigated using the hot-rolled steel sheets containing ultra-low C–2.3%Si–1.7%Mn-0.01%sol.Al of 2.3 mm thickness. The followings were found.When the hot-bands doesn't recrystallize after the hot-band annealing at 600 and 625°C, secondary recrystallization of the {110}<001> orientation mixed with the {211}k011l orientation forms. This is because the {110}k001l orientation density is too weak in the primary recrystallization texture. That also occurs when the inhibitor is too weak in the secondary recrystallization stage. Fully recrystallized hot-band after annealing at 700°C leads to no secondary recrystallization. The reason is that very coarse primary recrystallized grains at the center layer prevent secondary recrystallization. Secondary recrystallization of the {110}<001> orientation evolves completely when only near surface layer but not the center layer of the hot-band recrystallize after the hot-band annealing at 650 and 675°C. The reason is because amount of {110}<001> component in the primary texture, the inhibitor intensity and the primary matrix grain size structure are satisfied.
Linear Chain Compounds of Molybdenum(II) Acetate Linked by Pyrazine, 4,4′-Bipyridine, and 1,4-Diazabicyclo[2.2.2]octane (1995)

Abstract A series of linear-chain complexes of molybdenum(II) acetate linked by bidentate bridging ligands, [Mo2(O2CCH3)4L]n (L = pyrazine (pyz), 4,4′ -bipyridine (4,4′-bpy), and 1,4-diazabicyclo[2.2.2]octane (dabco)), have been prepared, and their crystal structures determined by an X-ray diffraction method. It has been shown that the relatively weak coordinations of the bridging ligands at the axial positions of Mo2(O2CCH3)4 (Mo–N = 2.619 (8)—2.658(6) Å) can effectively control the arrangement of the dimer units to give chain structures with good linearities. No significant interactions between the dimer units have been observed.
Globalization of Innovative Capabilities in the Late-industrializing Context: Evidence from Local Firms and TNC Subsidiaries in Brazil (2006)

This chapter seeks to contribute to the debate on the issues of globalization of firm-level innovative technological capability and industrial strategy in the late-industrializing context. Although these issues have been examined since the early 1970s in the late-industrializing literature, it becomes increasingly important today as globalization and trade liberalization gather pace and some developing countries and areas are coping well, while others are being left further behind (Lall, 2004). Thus, it is important to know the extent to which some developing countries and/or areas are really responding to such phenomena. There are two additional reasons for addressing these issues here.KeywordsForeign Direct InvestmentInnovative ActivityTechnological CapabilityLocal FirmExport PerformanceThese keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
(-)-.EPSILON.-Viniferin and related oligostilbenes from Carex pumila Thunb. (Cyperaceae). (1990)

Since e-viniferin (1) was first isolated as a phytoalexin of grapevine (Vitis vinifera, Vitaceae) leaves,1* it has been isolated from the bark of Vatica affinis (Dipterocarpaceae)2) and from seeds of Scirpus maritimus (Cyperaceae).3) (-)-e-Viniferin (la) and related oligostilbenes have also been isolated from the Carex species (Cyp-
Stochastic Frequency Masking to Improve Super-Resolution and Denoising Networks (2020)

Super-resolution and denoising are ill-posed yet fundamental image restoration tasks. In blind settings, the degradation kernel or the noise level are unknown. This makes restoration even more challenging, notably for learning-based methods, as they tend to overfit to the degradation seen during training. We present an analysis, in the frequency domain, of degradation-kernel overfitting in super-resolution and introduce a conditional learning perspective that extends to both super-resolution and denoising. Building on our formulation, we propose a stochastic frequency masking of images used in training to regularize the networks and address the overfitting problem. Our technique improves state-of-the-art methods on blind super-resolution with different synthetic kernels, real super-resolution, blind Gaussian denoising, and real-image denoising.
Time to end the routine testing of growth hormone and cortisol on hypoglycaemia screens? (2009)

We prospectively studied 124 consecutive hypoglycaemia screens performed on children attending our emergency department over a 27-month period (March 2006 to May 2008). In keeping with most other paediatric services in the UK, we routinely collect a number of samples to permit investigation of low blood sugar, including metabolic investigations, and a random cortisol and growth hormone. Most of these patients have an intercurrent illness and are subsequently thought to have had an episode of “physiological hypoglycaemia”. There is a paucity of published data examining how cortisol and growth hormone respond to hypoglycaemia and no previous work looking at …
Determination of Specific Gravity of Pigments (1948)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTDetermination of Specific Gravity of PigmentsW. W. Ewing and R. N. RhodaCite this: Anal. Chem. 1948, 20, 8, 743–745Publication Date (Print):August 13, 1948Publication History Published online1 May 2002Published inissue 13 August 1948https://pubs.acs.org/doi/10.1021/ac60020a018https://doi.org/10.1021/ac60020a018research-articleACS PublicationsRequest reuse permissionsArticle Views52Altmetric-Citations2LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
A low temperature process for phosphorous doped ZnO nanorods via a combination of hydrothermal and spin-on dopant methods (2013)

We demonstrate the fabrication of solution based low temperature-processed p-type ZnO NRs doped with phosphorous by using a spin-on-dopant method coupled with a hydrothermal process. We confirmed the incorporation of phosphorous dopants into a ZnO crystal by analyzing SIMS profiles, together with the evolution of the photoluminescence spectra. It is further revealed that the electrical properties of the p-type ZnO/n-type Si heterojunction diode exhibited good rectifying behavior, confirming that p-type ZnO NRs were successfully formed. In addition, we demonstrate that a piezoelectric nanogenerator with p-type ZnO NRs made on a glass substrate shows large enough power to drive polymer dispersed liquid crystal displays.
Characterization of Extracellular Dopamine Clearance in the Medial Prefrontal Cortex: Role of Monoamine Uptake and Monoamine Oxidase Inhibition (2001)

In vitro rotating disk electrode (RDE) voltammetry and in vivo microdialysis were used to characterize dopamine clearance in the rat medial prefrontal cortex (mPFC). RDE studies indicate that inhibition by cocaine, specific inhibitors of the dopamine transporter (DAT) and norepinephrine transporter (NET), and low Na + produced a 50–70% decrease in the velocity of dopamine clearance. Addition of the monoamine (MAO) inhibitors, l -deprenyl, clorgyline, pargyline, or in vivo nialamide produced 30–50% inhibition. Combined effects of uptake inhibitors with l -deprenyl on dopamine clearance were additive (up to 99% inhibition), suggesting that at least two mechanisms may contribute to dopamine clearance. Dopamine measured extracellularly 5 min after exogenous dopamine addition to incubation mixtures revealed that most conditions of DAT/NET inhibition did not produce elevated dopamine levels above controls. Inhibition of MAO produced elevated dopamine levels only after long-term, but not short-term, incubation in vitro . Short-term incubation of l -deprenyl combined with DAT and NET uptake inhibitors increased dopamine above control levels, consistent with more than one mechanism of dopamine clearance. Local infusion of pargyline (100 or 300 μ m ) into the mPFC or striatum via microdialysis produced more pronounced and immediate increases in mPFC dopamine levels compared with striatum. Furthermore, dopamine elevation in the mPFC was not accompanied by a decrease in the dopamine metabolites, 3,4-dihydroxyphenylacetic acid and homovanillic acid, as found in the striatum. These findings may have revealed a unique mechanism of mPFC dopamine clearance and therefore contribute to the understanding of multiple behaviors that involve mPFC dopamine transmission, such as schizophrenia, drug abuse, and working memory function.
Development of a modular single-axis slider for high precision positioning applications (2012)

Conference Name: 15th International Conference on Machine Design and Production, UMTIK 2012
Results of the Stable Microgravity Vibration Isolation Flight Experiment (1996)

This paper presents an overview of the STABLE microgravity isolation system developed and successfully flight tested in October 1995. A description of the hardware design and operational principles is given. A sample of the measured flight data is presented, including an evaluation of attenuation performance provided by the actively controlled electromagnetic isolation system. Preliminary analyses of flight data show that the acceleration environment aboard STABLE's isolated platform was attenuated by a factor of more than 25 between 0.1 and 100 Hz. STABLE was developed under a cooperative agreement between National Aeronautics and Space Administration, Marshall Space Flight Center, and McDonnell Douglas Aerospace. The flight hardware was designed, fabricated, integrated, tested, and delivered to the Cape during a five month period.
An IR spectroscopic study of acid centers on the surface of Al, Zr silica gels (2009)

Acid centers of Al, Zr silica gels with approximately equal aluminum ion contents (∼2.4% Al2O3) and various concentrations of Zr ions were studied by IR spectroscopy using the deuteroacetonitrile molecule as a probe. The surface of such samples was found to contain Lewis acid centers of two types, coordination unsaturated (I) silicon and (II) zirconium ions. An increase in the content of zirconium ions was accompanied by a decrease in the intensity of the 2328 cm−1 band in the IR spectra. This band was characteristic of interaction of CD3CN with Lewis acid centers of type I. The suggestion was made that this was caused by a decrease in the accessibility of coordination unsaturated silicon ions to CD3CN molecules.
Pressure-induced collapsed-tetragonal phase in<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:mrow><mml:msub><mml:mi>SrCo</mml:mi><mml:mn>2</mml:mn></mml:msub><mml:msub><mml:mi>As</mml:mi><mml:mn>2</mml:mn></mml:msub></mml:mrow></mml:math> (2015)

We present high-energy x-ray diffraction data under applied pressures up to $p=29\phantom{\rule{0.16em}{0ex}}\mathrm{GPa}$, neutron diffraction measurements up to $p=1.1\phantom{\rule{0.16em}{0ex}}\mathrm{GPa}$, and electrical resistance measurements up to $p=5.9\phantom{\rule{0.16em}{0ex}}\mathrm{GPa}$, on ${\mathrm{SrCo}}_{2}{\mathrm{As}}_{2}$. Our x-ray diffraction data demonstrate that there is a first-order transition between the tetragonal (T) and collapsed-tetragonal (cT) phases, with an onset above approximately 6 GPa at $T=7\phantom{\rule{0.16em}{0ex}}\mathrm{K}$. The pressure for the onset of the cT phase and the range of coexistence between the T and cT phases appears to be nearly temperature independent. The compressibility along the $a$ axis is the same for the T and cT phases, whereas, along the $c$ axis, the cT phase is significantly stiffer, which may be due to the formation of an As-As bond in the cT phase. Our resistivity measurements found no evidence of superconductivity in ${\mathrm{SrCo}}_{2}{\mathrm{As}}_{2}$ for $p\ensuremath{\le}5.9$ GPa and $T\ensuremath{\ge}1.8$ K. The resistivity data also show signatures consistent with a pressure-induced phase transition for $p \ensuremath{\gtrsim}5.5$ GPa. Single-crystal neutron diffraction measurements performed up to 1.1 GPa in the T phase found no evidence of stripe-type or A-type antiferromagnetic ordering down to 10 K. Spin-polarized total-energy calculations demonstrate that the cT phase is the stable phase at high pressure with a $\frac{c}{a}$ ratio of 2.54. Furthermore, these calculations indicate that the cT phase of ${\mathrm{SrCo}}_{2}{\mathrm{As}}_{2}$ should manifest either A-type antiferromagnetic or ferromagnetic order.
DNA and protein applications of near-infrared dyes (2002)

The near-infrared region of the spectrum (650-1100 nm) offers distinct advantages over the traditional UV/vis region for spectroscopic measurements. In the past, the lack of commercially available equipment capable of working in the near infrared limited the utility of near-infrared techniques. However, since the advent of photodiodes and semiconductor lasers, much progress has been made in the development of near-infrared techniques. This paper discusses the use of near-infrared dyes used in DNA and protein applications.
Effect of Short Term Graded Withdrawal of Nasal Continuous Positive Airway Pressure on Systemic Blood Pressure in Patients with Obstructive Sleep Apnoea (1996)

It is debated whether obstructive sleep apnoea (OSA) is a significant independent risk factor for sustained hypertension or cardiovascular morbidity and mortality. In an attempt to avoid the problem of confounding variables we have investigated whether withdrawing nasal continuous positive airway pressure (NCPAP) from patients with OSA for different proportions of the night leads to a subsequent rise in their morning blood pressures. Six patients with treated OSA had their NCPAP automatically varied between 3 cms H2O and a therapeutic pressure over 5 successive nights. The proportion of therapeutic NCPAP given was kept constant over the 5 nights and blood pressure measured the morning after the 5th night. Each patient had 5 different levels of sleep disruption, from no therapeutic NCPAP at all, through to 100% NCPAP. The nocturnal consequences of these different proportions of NCPAP were quantified both by oximetry and by a new EEG analysis that provides an objective estimate of the periodicity (fluctuations in the EEG depth) of the time course seen in patients with OSA. Increasing degrees of nocturnal hypoxic dipping and EEG periodicity were positively correlated with the subsequent morning systolic and diastolic blood pressures (p < 0.02). About 20% of the variance in systolic and diastolic blood pressure could be accounted for by the amount of either hypoxic dipping or EEG periodicity. The results of this study suggest that acute changes in awake blood pressure can be caused by sleep apnoea. It agrees with other data suggesting that OSA can have an independent influence on morning BP, but that this effect may have worn off by the afternoon and evening. Some of the discrepancies between the numerous studies in this area may be due to the timing of blood pressure measurements.
Algorithmes d'amincissement d'images sur machines parallèles (1993)

Le theme de ce memoire est l'etude de la parallelisation d'algorithmes de traitement d'images. Une operation particuliere du traitement d'images est retenue et etudiee en detail. Les algorithmes existants sont compares et analyses. L'etude de cette operation est ensuite reprise sous l'angle du parallelisme. La procedure retenue est celle d'amincissement d'image (ou thinning). Cette operation est basee sur la definition d'un descripteur de forme donnee par h. Blum en 64. Nous abordons ce sujet par le biais de l'algorithmique parallele. La programmation de machines paralleles a memoire distribuee et a usage general est notre modele de reference. De nouveaux outils de parallelisation, ainsi que de nouveaux algorithmes paralleles sont proposes. Une etude de la complexite sequentielle et parallele du probleme est proposee
Single-electron tunnel junction array (1989)

The authors have carried out an analysis of statics and dynamics of uniform one-dimensional arrays of ultrasmall tunnel junctions. The correlated single-electron tunneling in the junctions of the array results in its behavior qualitatively similar to that of the Josephson transmission line. In particular, external electric fields applied to the array edges can inject single-electron-charged solitons into the array interior. Shape of such soliton and character of its interactions with other solitons and the array edges are very similar to those of the Josephson vortices (sine-Gordon solitons) in the Josephson transmission line. Under certain conditions, a coherent motion of the soliton train along the array is possible, resulting in generation of narrowband SET oscillations with frequency f/sub s/ = /e where is the dc current flowing along the array.
EvolTrack: improving design evolution awareness in software development (2010)

Abstract Software differs from most manufactured products because it is intangible. This characteristic makes it difficult to detect, control, and understand how it evolves. This paper presents an approach based on software visualization that can detect and externalize design evolution made in a software project during its initial development or at any further phase. By using this approach, a developer can be aware of the current state of the software as a whole and can additionally verify if the current design, also called emerging design, is evolving according to the team expectations and leader guidance, preventing problems caused by misunderstandings of the expected software solution. The approach was evaluated with free/open source software (FOSS) projects. The results indicate that the approach behaves as expected when applied to real software development projects, with minor performance bottlenecks.
Ku-Band Cross-Coupled Ceramic SIW Filter Using a Novel Electric Cross-Coupling (2015)

International audience
LPE Growth of In<sub>1-x</sub>Ga<sub>x</sub>As<sub>1-y</sub>P<sub>y</sub> on GaAs<sub>0.7</sub>P<sub>0.3</sub> (1986)

Various In 1- x Ga x As 1- y P y epitaxial crystals with mirror-like surfaces were grown on GaAs 0.7 P 0.3 substrates by LPE employing the two-phase-solution technique. The arsenic atomic fraction in the melt ( X As l ) first increased with increasing X Ga l , but decreased above an X Ga l value of 0.03, while the solid As composition (1- y ) increased monotonically. This somewhat strange behavior is explained as an increase in the As segregation coefficient with the increase in the As or Ga solid composition ( x or 1- y ), which results from the large value of the GaAs fusion temperature.
Binary mask optimization for forward lithography based on boundary layer model in coherent systems: erratum (2009)

Get PDF Email Share Share with Facebook Tweet This Post on reddit Share with LinkedIn Add to CiteULike Add to Mendeley Add to BibSonomy Get Citation Copy Citation Text Xu Ma and Gonzalo R. Arce, "Binary mask optimization for forward lithography based on boundary layer model in coherent systems: erratum," J. Opt. Soc. Am. A 27, 82-84 (2010) Export Citation BibTex Endnote (RIS) HTML Plain Text Citation alert Save article
Complete characterizations of the subdifferential of convex integral functions II: Qualification conditions, conjugate and sequential formulae (2018)

This work provides formulae for the $\epsilon$-subdifferential of the integral functional given by the following expression \begin{equation*} 
I_f (x):=\int\limits_T f(t,x) d\mu(t) \end{equation*} where $(T,\Sigma,\mu)$ is a complete $\sigma$-finite measure space, the nominal data $f:T\times X\to \overline{\mathbb{R}}$ is a convex normal integrand and the space $X$ is a locally convex topological space. This paper is a direct continuation of [19]. Here we focus our attention on present simplifications of the formulae previously established in the mentioned paper under the qualification condition given by the continuity of $I_f$ and the nominal data $f_t'$s. Formulae for the conjugate and sequential representation of the subdifferential of the integral function $I_f$ are also presented.