gebhart/patrepeval huggingface dataset:
Optical limiting properties of neutral nickel dithiolenes (1999)

Wide applications of lasers have stimulated a great interest in development of optical limiting devices. These devices can be used to protect optical sensor form laser-induced damage because their transmission is high when they are exposed to low-power laser light, and their transmission becomes low when irradiated by intense laser beams. Here we report such a device based on nonlinear optical effects in two neutral nickel complexes with multi-sulfur 1,2 dithiolene ligands, 1 and 2. The limiting device consisted of a focusing setup and a 1-mm-thick cell, which contained a benzene solution of one of the complexes. THe limiting properties were investigated by both nanosecond and picosecond laser pulses. At 532 nm, the limiting thresholds of complexes 1 and 2 measured by the picosecond laser pulses. At 532 nm, the limiting threshold of complexes 1 and 2 measured by the picosecond laser pluses with a focusing geometry were determined to be approximately 0.3 J/cm<SUP>2</SUP>. The linear absorption spectra of the to complexes also indicated that their limiting response should cover the visible and near-IR region. All these result show their limiting performance is superior to the limiting effecting C<SUB>60</SUB>. Picosecond time-resolved pump-probe and Z-scan experiments revealed that the observed limiting effects should originate from excited-state absorption and refraction.
Transient Heat Transfer by Free Convection from a Vertical Flat Plate : Contribution to the Siegel's Analysis (1960)

We propose both an improvement of accuracy and a specification of effects of Prandtl numbers for Siegel's analysis on the transient free convection from a vertical flat plate of infinite width and finite length, which is initially at the ambient temperature in a quiescent fluid and is suddenly raised to a uniform higher temperature. The precise solutions for velocity and temperature profiles of differential equations for the initial stage of motion are obtained for any Prandtl numbers and also confirmed to be extremely the good approximation for steady state. As we use the above-mentioned solutions to obtain solutions to the time-dependent free convection equations of momentum and energy in an integral form, it will be expected that the present solutions hold a good accuracy for times, at which the purely one-dimensional heat transfer is terminated and the steady flow is established as a function of position along the plate.
Seroepidemiology of dengue and other arboviruses in a natural population of toque macaques (<i>Macaca sinica</i>) at Polonnaruwa, Sri Lanka (1993)

A seroepidemiological study of arboviruses infecting 115 wild toque macaques (Macaca sinica) at Polonnaruwa, Sri Lanka showed a high prevalence of antibodies to dengue and Lumbo viruses. There was low seroprevalence of Chandipura (2/115) and Batai (1/115) virus antibodies, but no seropositivity to Chikungunya or Sindbis. There was no serological evidence of infection by Japanese encephalitis (JE) virus in spite of large human epidemics in the study area, indicating that toque macaques are unlikely to be an epidemiologically relevant host in the maintenance cycle of JE virus.
ChemInform Abstract: Non‐Metathesis Ruthenium‐Catalyzed C—C Bond Formation (2001)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
<b>SIGMOISIDE E: A NEW ANTIBACTERIAL TRITERPENOID SAPONIN FROM <i>ERYTHRINA SIGMOIDEA</i> (HUA)</b> (2007)

Chemical analysis of the stem bark of Erythrina sigmoidea (Leguminoseae) yielded two known isoflavones, 6,8-diprenylgenisteine (3) and warangalone (4) as well as a new triterpenoid saponin designated sigmoiside E (1). Its structure was established by chemical and spectroscopic means as 16-O-β-D-galactopyranosyl maniladiol (1). Sigmoiside E exhibited antibacterial activity against gram-negative bacteria. KEY WORDS: Erythrina sigmoidea, Stem bark, Triterpenoid, Saponin, Isoflavone, Leguminoseae Bull. Chem. Soc. Ethiop. 2007, 21(3), 373-378.
Antimycoplasmal activities of the speudomonic acids and structure-activity relationships of monic acid A derivatives. (1988)

The antimycoplasmal activities of the pseudomonic acids isolated from Pseudomonas fluorescens NCIB 10586 are reported. Structure-activity relationships of a variety of ester, amide and thiol ester derivatives of the nucleus, monic acid A, are described. Enhanced antimycoplasmal activity is reported for a number of monic acid A esters and the most potent derivative, m-nitrobenzyl monate A, is a 100-fold more active against Mycoplasma hyopneumoniae than pseudomonic acid A.
Caged Mono- and Divalent Ligands for Light-Assisted Disruption of PDZ Domain-Mediated Interactions (2013)

We report a general method for light-assisted control of interactions of PDZ domain binding motifs with their cognate domains by the incorporation of a photolabile caging group onto the essential C-terminal carboxylate binding determinant of the motif. The strategy was implemented and validated for both simple monovalent and biomimetic divalent ligands, which have recently been established as powerful tools for acute perturbation of native PDZ domain-dependent interactions in live cells.
Microwave-Material Interaction in Oxide Ceramics with Different Additives (2006)

A systematic study upon microwave (2.45 GHz frequency) and conventional heating (resistance heating furnace) was undertaken on porosity, grain growth and densification of commercial grade Al2O3-ceramics doped with MgO (aliovalent doping), with ZrO2 (grain boundary pinning) and with additives promoting elongated grain growth (LaAlO 3 and La2O3, AlPO4). Processes accompanied by a strong non-equilibrium situation, e.g., dissolution, segregation, vacancy formation, are influenced by the presence of the microwave field during heat treatment, visible on microstructure differences of microwave as compared to conventionally sintered samples. Regular grain growth is almost not affected by the microwave field, but the on-set of exaggerated grain growth and pore coalescence is delayed and occurs at higher density as compared to conventional sintering. Such microstructure differences seem to be more pronounced if the surface to volume ratio of the samples is low, therefore volumetric heating has a larger contribution to transport phenomena as compared to small samples.
Native-oxide-defined coupled-stripe Al<i>x</i>Ga1−<i>x</i>As-GaAs quantum well heterostructure lasers (1991)

Data are presented on the continuous-wave (cw) room-temperature (300 K) operation of multiple stripe AlxGa1−xAs-GaAs quantum well heterostructure (QWH) laser arrays defined with native oxide contact masking. Use of the native AlxGa1−xAs(x≳0.7) oxide allows the fabrication of high-performance devices without depositing foreign oxide or dielectric layers (SiO2 or Si3N4). Arrays of ten 5-μm-wide emitters on 7 μm centers are coupled and operate at powers as high as 300 mW per facet, or at wider stripe spacing (5 μm emitters on 10 μm centers) as high as 400 mW per facet. These data indicate that current blocking layers of native oxide, formed from AlxGa1−xAs with H2O vapor in N2 carrier gas (400 °C, 3 h), can be used in the construction of high-power multiple stripe QWH arrays with excellent performance characteristics.
Immediate and Long-Term Outcomes of Reperfusion Therapy in Patients With Cancer (2021)

In patients with active cancer, reperfusion therapy showed similar adverse events and short-term outcomes to that of other groups. While long-term prognosis was worse in the active cancer group than the nonactive cancer groups, not negligible number of patients had good functional outcomes, especially those with determined stroke mechanisms.
Cardiovascular Magnetic Resonance: Established and Emerging Applications (2004)

BASICSPhysics of MRI-Basic Principles, F.H. Epstein and J.R. BrookemanMR Contrast Agent Basics, R.M. Wiesskoff and P. CaravanCardiac Magnetic Resonance Spectroscopy, S. NeubauerQuantitative Image Analysis, N.F. OsmanReal-time CMR and Parallel Imaging, D.K. SodicksonCORONARY ARTERY DISEASE AND MYOCARDIAL CONSEQUENCESMyocardial Function and Stress Imaging , E. NagelCMR of Myocardial Perfusion, J. SchwitterCMR of Myocardial Viability, A. Wagner, H. Mahrholdt, L. Thompson, U. Sechtem, R.J.M. Kim, and R.M. JuddCoronary Magnetic Resonance Angiography, D. Li and V. DeshpandeSTRUCTURAL HEART DISEASECMR Evaluation of Cardiac Valvular Disease, C.H. Scott, V.A. Ferrari, and C.H. LorenzCMR in Congenital Heart Disease, M.A. FogelCMR in Cardiomyopathy, S.K. Prasad and D.J. PennellCMR of Cardiac Masses and Thrombi, C.M. Bove and C.M. KramerCMR of Pericardial Disease, D. Bluemke and G. SzarfSYSTEMIC ARTERIAL DISEASEContrast-enhanced Magnetic Resonance Angiography, J.H. Maki, M.K. Knopp, and M.R. PrinceCMR of Aortic Disease, J.C. Carr and J.P. FinnCMR Atherothrombotic Plaque Imaging, Z.A. Fayad, V. Fuster, and R.P. ChoudhuryTransesophageal CMR of the Aorta, S. Gautman, W.P. Warren, and J.A.C. LimaCMR in the Assessment of Pulmonary Hypertension, H.V. Dihn, J.P. Goldman, and M. PoonINTERVENTIONAL CMRInternal Coils in CMR, E. AtalarThe Cardiovascular Interventional MRI Suite: Design Considerations, M.A. Guttman, R.J. Lederman, and E.R. McveighEarly Experience with Combined CMR and X-ray Suites, O.M. Weber, M. Saeed, A.J. Martin, P. Moore, R. Higashida, S. Schalla, T. Kuehne, R. Lee, and C.B. HiggensMRI-guided Cardiovascular Intervention, X. Yang and A.C. LardoMRI-guided Drug and Cell Injection Therapies for Heart Disease, A.J. Dick, V.K. Raman, M.A. Guttman, D.C. Peters, E.R. McVeigh, R.J. LedermanMRI-guided Interventional Electrophysiology, A.C. Lardo, T. Dickfeld, and H. HalperinEMERGING CMR APPLICATIONSMRI of Angiogenesis, J.D. Pearlmann, L. Gao, and M. SimonsMolecular Imaging, G.M. Lanza, S.D. Caruthers, and S.A. WicklineHigh-field CMR, M. StuberCMR CLINICAL LABORATORY AND ECONOMICSAn Introduction to CMR for Technologists, C.R. ComeauHow to Set Up a CMR Laboratory and Program, S. Frohwein, A. Yegin, V. Fuster, and Z.A. FayadDeveloping Cost-effective Strategies for CMR, L.J. Shaw and T.J. RobertsonIndex
Narrow linewidth, high speed, AlInGaAs, strained MQW, 1.55 μm, DFB laser diodes (2002)

Extremely narrow linewidth (⩽100 kHz), DFB laser diodes using an optimized strain-compensated eight quantum well AlInGaAs active region with 20 GHz f/sub -3dB/ are presented.
NUMERICAL SOLUTION OF FUEL-ELEMENT THERMAL-STRESS PROBLEMS (1960)

In developing a method of numerical analysis for the solution of thermal- stress problems special emphasis was given to fuel elements with internal coolant channels. Numerical techniques ior reducing the partial differential equation system te a form suitable for numerical solution and a new iteratlve method of solving large systems of linear algebraic equations were employed. Computer codes were devised to obtain the numerical solution of the thermal-stress problems and were used to obtain numerical results for single-hole and seven-hole hexagonal elements and plate-type elements. Comparisons were made between analytical results and numerical results for the case of t:.ie simple annulus shape. (auth)
Short‐term studies on the in vivo metabolism of<i>N</i>‐oxides of nicotine in rats (1986)

This study was designed to examine the in vivo reduction of the N-oxidation products of nicotine metabolism in rats. Male Fischer-344 rats were divided into one control and three experimental groups (n = 20). Each treatment group received either 0.02% trans-nicotine N'-oxide, 0.02% cis-nicotine N'-oxide, or 0.02% nicotine N,N'-dioxide in drinking water for 3 wk. After 7 d of metabolite administration, plasma nicotine levels in the trans-nicotine N'-oxide group rose to twice that of the cis-nicotine N'-oxide or nicotine N,N'-dioxide group. Plasma cotinine [1-methyl-5-(3-pyridinyl)-2-pyrrolidinone] concentrations reached maximum levels during wk 1 in the cis-nicotine N'-oxide and nicotine N,N'-dioxide groups but continued to increase for another 7 d in the trans-nicotine N'-oxide group. At d 15 and again at d 21, rats from each group (n = 10) were placed in metabolism chambers and given 50 ml tap water over a 24-h period. Analysis of urine obtained from a metabolism-chamber study conducted after 15 d of consumption revealed concentrations of nicotine in the trans-nicotine N'-oxide group that were 3 times higher than cis-nicotine N'-oxide-treated animals. Urinary cotinine levels were similar in all three groups. Results from a second chamber study (d 21) showed similar urinary nicotine and cotinine values in all treatment groups. Plasma total triiodothyronine (TT3) concentrations were reduced in all treatment groups during the first week. Plasma total thyronine (TT4) concentrations were reduced (p less than 0.05) in the trans-nicotine N'-oxide and cis-nicotine N'-oxide treatment groups during the first week. Plasma total thyronine (TT4) concentrations cis-nicotine N'-oxide is presented. An analytical method for separation of nicotine, cotinine, and cis- and trans-nicotine N'-oxide, as well as cis- and trans-nicotine N,N'-dioxide, is also outlined.
Photoelectrochemical Performance of Anatase TiO[sub 2] Thin Films Deposited by Self-Limiting Growth Techniques (2010)

Anatase photoanodes were deposited by self-limiting growth techniques at low temperature. The optical bandgap and flatband voltage of the as-deposited films agree with the values obtained from single crystal anatase. The donor density could be increased by both UV illumination and cathodic polarization in acidic solutions. Improvements in photocurrent scaled closely with changes in carrier concentration, with over 20-fold enhancements observed over the as-deposited films. The threshold potential for hydrogen intercalation was −0.6 V vs Ag/AgCl. At this level the carrier concentration could be manipulated with no change in optical transmission. At lower potentials irreversible changes are observed which are attributed to the reduction of the underlying indium tin oxide contact. In contrast, no changes were observed when fluorinated tin oxide was used as the contact layer.
ChemInform Abstract: SYNTH. VON (+‐)‐FUMARICIN UND SEINES DIASTEREOMEREN (1970)

Abstract Das Brom‐indanon (I) wird durch katalytische Hydrierung debromiert und mit Isopentylnitrit in das Ketoxim‐Keton (II) übergeführt.
Behavioral and Physiological Effects of Ethanol in High‐Risk and Control Children: A Pilot Study (1983)

Blood and breath acetaldehyde levels were measured following ethanol ingestion (0.5 ml/kg) In 11 boys familially at risk for alcoholism and 11 age‐matched controls. No significant differences were found between groups for acetaldehyde, objective, or subjective measures of intoxicatlon. Previous reports of acetaldehyde as a marker of risk for aloholism were not confined. Baseline behavioral state predicted response to alcohol. Children tended to have a subjective response in a direction opposite from the baseline mood state.
In vitro cytotoxicity of carbon nanoparticlesagainst Hep G 32 cells (2011)

The aim of the present study was to evaluate the in vitro toxicity of two multi wall carbon nanotubes (MWCNT) on human hepatocytes (Hep G 32 cell lines). The toxic effects of carbon nanoparticles were analyzed after 48 h of incubation with Hep G 32 cells using MTT assay and also estimated the levels of LDH (that is leakage into the media). The results of the LDH estimation demonstrated that exposure of multi wall carbon nanotubes to hepatocytes (Hep G 32) for 48 h resulted in concentration-dependent increase in LDH leakage and exhibited a significant (p < 0.05) cytotoxicity at 3-50 μg/ml. Incubation of carbon nanotubes with liver cells produced a dose dependent inhibition of growth of the cells. The TC<sub>50</sub> or IC<sub>50</sub> values (toxic concentration 50 i.e. concentration of particles inducing 50 %cell mortality) of two nanoparticles were found in the range of 36.99-37.15 μg/ml, which were less than that of quartz (known toxic agent, 39.85 μg/ml), indicating the toxic nature of carbon nanoparticles
Some observations on the formation of diamond from glassy carbon (1978)

Glassy carbon preheated at 2000°C was exposed under 90 kb and 65 kb at high temperatures in order to elucidate the processes of the graphitization and the formation of diamond from the carbon with the characteristic bond nature under high pressure and temperature conditions. In the present work, the process of the diamond formation as the stable phase was followed by the X-ray diffraction method and the scanning electron microscopic observation. The diamond well developed with the {111} face was found to form on a graphite grain, which had been grown as a meta-stable phase under high pressures and temperatures.
Prolactin Regulation of Islet-Derived INS-1 Cells: Characteristics and Immunocytochemical Analysis of STAT5 Translocation* (1997)

The major changes in pancreatic islet function during pregnancy and after exposure to lactogens are an increase in beta-cell proliferation and enhanced insulin secretion. In this study we examined INS-1 cells as a potential model for further inquiry into PRL signaling in beta-cells. Proliferation of beta-cells, insulin secretion, and quantitative immunocytochemical analysis of STAT5 translocation were studied. PRL treatment of INS-1 cells resulted in a 2- to 4-fold increase in cell proliferation compared to that in the control group. In contrast, there was no effect of PRL treatment on HIT cell proliferation and only a very small effect on RIN cell proliferation. A significant effect on INS-1 cell proliferation was observed at 10 ng/ml and reached a maximum at 200 ng/ml. PRL treatment resulted in enhanced insulin secretion from INS-1 cells. There was a time-dependent increase in insulin secretion, which when corrected for cell number was 1.5-fold greater in the PRL-treated cells. The effects of PRL on cell division and insulin secretion were glucose dependent. The presence of the JAK family of tyrosine kinases and the transcription factor STAT5 in INS-1 cells was examined by immunocytochemical techniques. Although all members of the JAK family of kinases were detected, the staining intensity of JAK-2 was noticeably more intense. Initial studies of STAT5 translocation were performed using PRL-dependent Nb2 lymphoma cells, in which PRL treatment resulted in a nearly complete translocation of cytoplasmic STAT5 to the nucleus. Under control conditions there was a near-equal fluorescence intensity of STAT5 staining in the nucleus and cytoplasm of INS-1 cells. PRL treatment resulted in a time-dependent increase in STAT5 staining in the nucleus, with a corresponding decrease in the cytoplasm. The STAT5 staining intensity in the nucleus remained elevated for the duration of PRL treatment. This effect was reversible upon removal of PRL from the medium. Besides PRL, both GH and FBS induced a similar translocation of STAT5 to the nucleus. Although present in RIN cells, no detectable changes in STAT5 were observed in RIN cells after exposure to PRL, GH, or FBS. INS-1 cells should provide a good model for further inquiry into the intracellular signaling pathways used by PRL and how these events alter islet function.
EXPERIMENTAL STUDY OF BUBBLE DYNAMICS DURING NUCLEATE FLOW BOILING ON HORIZONTAL AND VERTICAL SURFACES (2014)

Knowledge of the physical mechanisms governing bubble dynamics and two-phase heat transfer is required to develop mechanistic models and to accurately predict and scale the performance of two-phase systems in reduced gravity environments. To better understand the effect of the magnitude of gravity on flow boiling, especially the dynamics of single bubbles under different levels of bulk liquid velocity, surface orientation at earth normal gravity and contact angle effects were studied in this work. A microfabricated nucleation site (10 mm in diameter) at the center of a flat heating surface was used to generate bubbles. Silicon and aluminum were used as substrate materials, with static contact angles of 56° and 19°, respectively, and water as the test liquid. Bulk liquid velocities ranged from 0 to 0.25 m/s, for horizontal and vertical surface orientations, in upflow conditions. Bulk liquid temperature was set close to saturation temperature, with bulk liquid subcooling less than 1°C, and wall superheat was maintained between 5.0°C and 6.0°C. The experimental results for bubble growth, departure diameter and time for departure, bubble sliding distance and velocity, bubble lift-off diameter and time for lift-off, and bubble base diameter are reported for vertical and horizontal orientations, as the system variables were varied parametrically. It is found that irrespective of orientation and contact angle, departure and lift-off diameters decrease with increase in bulk liquid velocity. At a given velocity, departure diameter decreases with increase in the component of gravity parallel to the heater surface. For a given bulk liquid velocity, increase in contact angle results in increase in bubble departure and lift-off diameters, for all orientations. For given conditions, bubble lift-off diameter increases with decrease in the component of gravity normal to the heater surface. The effect of gravity on lift-off diameter is reduced at high liquid bulk velocities. For given orientation and flow velocity, sliding distance decreases monotonically with decrease in contact angle. The bubble velocity at lift-off increases with increase in flow velocity and increase in the component of gravity parallel to heater surface.
Characterization of α-(1→3) branched oligosaccharides synthesized by acceptor reaction with the extracellular glucosyltransferases from L. Mesenteroides NRRL B-742 (1992)

International audience
Impact of Behavior Genetics on Medicine and Society (2008)

Understanding the role of genes in human behavior will impact both medicine and society, but not always in the manner expected. Knowledge about behavioral genes can be used for the good, for example by improving psychiatric diagnoses, developing new drugs to treat mental illnesses, and dispelling harmful myths about certain types of human variation. However, the same sort of information could be used to discriminate against people, to provide quick fixes for social problems, or to support eugenics. How we use the new knowledge about molecular behavior genetics will depend on the legal, ethical and social policies that we develop.To watch Dr. Hamer's presentation, please see the "Google Video posting.":http://video.google.com/videoplay?docid=-9036771709057660539&hl=en To watch the deliberative discussion concluding the Symposium after this last presentation, please see the "Google Video posting.":http://video.google.com/videoplay?docid=-4540711705005631053&hl=en
Cybr, a cytokine-inducible protein that binds cytohesin-1 and regulates its activity (2002)

Cytokines regulate lymphocyte development and differentiation, but precisely how they control these processes is still poorly understood. By using microarray technology to detect cytokine-induced genes, we identified a cDNA encoding Cybr, which was increased markedly in cells incubated with IL-2 and IL-12. The mRNA was most abundant in hematopoietic cells and tissues. The predicted amino acid sequence is similar to that of GRP-1-associated protein (GRASP), a recently identified retinoic acid-induced cytohesin-binding protein. Physical interaction, dependent on the coiled-coil domains of Cybr and cytohesin-1, was demonstrated by coimmunoprecipitation of the overexpressed proteins from 293T cells. Cytohesin-1, in addition to its role in cell adhesion, is a guanine nucleotide-exchange protein activator of ARF GTPases. Acceleration of guanosine 5prime prime or minute-O-(thiotriphosphate) binding to ARF by cytohesin-1 in vitro was enhanced by Cybr. Because the binding protein modified activation of ADP ribosylation factor by cytohesin-1, we designate this cytokine-inducible protein Cybr (cytohesin binder and regulator).