gebhart/patrepeval huggingface dataset:
Large-Volume Plasma Device with Internally Mounted Face-Type Planar Microwave Launchers for Low-Temperature Sterilization (2015)

In this study, large-volume microwave excited surface-wave and volume-wave plasmas were investigated for low temperature sterilization of medical instrument. The two planar microwave launchers, each supported by a 1.5-kW magnetron, were face-to-face installed inside the vacuum chamber of plasma device for homogeneous sterilization. The spatial distributions of plasma discharges in the surface-wave and volume-wave modes were characterized under various discharge conditions using single or double microwave launchers of the experimental setup. The electron density increased to about twice in the case of double launchers as compared to single launcher without any microwave interference between two launchers. With this plasma setup, we confirmed the successful inactivation of Tyvek-wrapped spore-forming bacteria at temperatures less than 70°C and within 70 to 80 min with time-modulated surface-wave and volume-wave plasma, respectively.
Assessment of the Thickness Variation and Surface Roughness of Aqueous Film Coated Tablets Using a Light-Section Microscope (1995)

The Light-Section Microscope measures the thickness and surface roughness of transparent film coats without contacting them. It enables the determination of tablet film coat thickness at different regions on a tablet surface and analysis of coat thickness variation. Examination of aqueous film coated tablets using a Light-Section Microscope has shown that the coat application conditions can influence the film density and thickness, film thickness variation and film coat surface roughness. Coat application conditions which give rise to smoother surfaces are shown to produce more dense, thinner coats which may exhibit a more even thickness on smooth substrates but larger variations in film thickness on rough substrates. The potential for film thickness and surface roughness to vary at different positions on the substrate surface has also been demonstrated, with film coats tending to be smoother and thinner at the periphery of tablet faces.
ChemInform Abstract: PROTON TRANSFER FROM HETEROCYCLIC COMPOUNDS. PART 7. PURINE‐CONTAINING DRUGS (1980)

Abstract Die Geschwindigkeitskonstanten für die C(8)‐Detritiierung pseudoerster Ordnung der Titelverbindungen (I)‐(III) bei 85°C betragen (0.14‐344)·10 ‐5 /s, wobei die Werte mit steigender Acitität z.B. für (I) in den 3 pH‐Bereichen unter 4,4‐9 und über 10 unterschiedlich stark zunehmen.
<title>Modeling of laminar e-beam source for SCALPEL</title> (1999)

The SCALPEL e-beam lithography tool requires an extremely uniform e-beam to illuminate the Mask. To meet this requirement, the SCALPEL POL tool source cathode operates in the temperature limited mode. In this mode, all cathode irregularities are imaged at the Mask plane due to the high DOF of the gun immersion objective. We have studied the possibility of Mask illumination with a laminar e-beam having its virtual source located beyond the immersion objective DOF. In this case, using a positively biased Wehnelt, one can obtain a laminar e-beam that provides high emittance and low brightness illumination, while also yielding an efficient in- gun correction of beam properties.
MOLECULAR STRUCTURE AND PHYSICAL BEHAVIOR OF POLYMERS. Progress Report No. 8, May 1, 1962-July 31, 1962 (1962)

Crosslinked polyethylene films were prepared by gamma irradiation of molten linear polyethylene in vacuo. Various degrees of orientation were imposed by stretching testpieces to fixed lengths in the molten state. The dependence of the tensile stress upon temperature was then determined over the temperature range 150 to 110 deg C. The tensile stress at constant length decreased markedly as crystallization developed. The temperature of incipient crystallization, marked by the onset of the stress reduction, increased with the imposed extension. At a lower temperature, which did not depend significantly on the degree of extension, the tensile stress began to rise sharply with further cooling. This is attributed to the growth of folded chain crystals. Studies were also made on the isomerization reactions of polystyryl lithium in benzene solution. It was found that, after several hours at 75 deg C, an amount of lithium hydride was formed corresponding to 50% of the original organolithium content. This agrees with the mechanism proposed for the case of polystyryl sodium in tetrahydrofuran. (auth)
Guide to MS605 Anita Lee Blair papers (2018)

An educator, lecturer, political activist, and state legislator, Anita Lee Blair (1916-2011) advocated for safety and accident prevention, disability and women’s rights, and transparency and accessibility in government. The Anita Lee Blair papers date 1944-2011, bulk 1946-1953. Types of records include photographs, correspondence, clippings, publications, scrapbooks, books, and other printed materials. Arranged in three series (Biographical Information, Safety Lecturer Career, and Legislative and Political Career), these papers document Blair’s life and career as a Texas state legislator and as a freelance safety lecturer.
Presurgical Finite Element Analysis from Routine Computed Tomography Studies for Craniofacial Distraction: II. An Engineering Prediction Model for Gradual Correction of Asymmetric Skull Deformities (1998)

Finite element analysis from routine computed tomography studies (CT/FEA) allows clinicians to predict the mechanical and anatomic consequences of specific distraction systems before human application. A realistic three-dimensional CT/FEA engineering model of an actual plagiocephalic infant with unicoronal synostosis was developed using 4215 parabolic triangular shell elements and intracranial pressure conditions ranging from 10 to 20 mmHg. The completed finite element analysis model was used to predict the anatomic outcome of multiaxial distraction delivered by hypothetical patterns of rod and node distraction units. The predictions for the various patterns of distraction units were also compared quantitatively with respect to force, stress, strain, and intracranial volume. Best anatomic corrections were achieved with bilateral patterns of distraction units that simultaneously elongated the ipsilateral cranium and shortened the contralateral cranium. Greatest strain levels were experienced within the osteotomy callus, greatest stress levels at the appliance anchorage sites, and the greatest rod force at the ipsilateral lower coronal position.
Physiological Response to Submaximal Isometric Contractions of the Paravertebral Muscles (1999)

At a threshold intramuscular pressure of 30-40 mm Hg during muscle contraction, oxygenation in the paravertebral muscles is significantly reduced. The effect of further increase in intramuscular pressure on tissue oxygenation over time may be compensated for by an increase in blood pressure and heart rate. Surface electromyogram amplitudes and intramuscular pressure can be used as indicators of paravertebral muscle force.
Perturbation technique for laser-induced thermal response with thermal radiation boundary conditions (1990)

Closed form analytic solutions of uansient thermal response in materials simultaneously receiving laser irradiation and thermally re-radiating energy is impossible because of boundary condition non-linearity. Therefore, this problem must either be solved computationally to the desired accuracy, or by neglecting the surface thermal re-radiation. This paper presents a combined perturbation theoryLaplace transform technique to determine approximate analytic solutions for constant properties without neglecting the thermal radiative boundary condition and applies these solutions to laser-driven material thermal response. Dimensional analysis identifies the important non-dimensional parameters governing general solution behavior and characteristics. These non-dimensional parameters uniquely define the perturbation solution behavior and characteristics, in particular accuracy limitations since this is an approximate analytic technique. Proper application of the perturbation solutions to thin wall and semi-infinite wall analysis cases and to a wide variety of high heat flux target materials is discussed. In general, the thermal re-radiation significantly enhances a given material's capability to survive high laser flux impingement due to the significant cooling effect at high temperatures. The perturbation solutions accurately quantify this material response enhancement, thereby better establishing a material's actual thermal response under realistic laser flux impingement conditions (i.e., accounting for thermal reradiation) due to increased first-order accuracy. i
Multiple forms of fructose diphosphate aldolase in mammalian tissues. (1966)

Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans the biological, physical, and social sciences.
Multiple Symmetric Lipomatosis Presenting with Bilateral Brachial Plexopathy (2015)

Multiple symmetric lipomatosis (MSL), also called Madelung's disease, is a rare disease characterized by the growth of nonencapsulated masses of adipose tissue. Herein we report on a case of bilateral brachial plexopathy caused by extensive lipoma associated with MSL.
A large-signal SOI MOSFET model including dynamic self-heating based on small-signal model parameters (1999)

A new technique for a large-signal SOI MOSFET model with self-heating is proposed, based on thermal and electrical parameters extracted by fitting a small-signal model to measured s-parameters. A thermal derivative approach is developed to calculate the thermal resistance when the isothermal dc drain conductance is extracted from small-signal fitting. The thermal resistance is used to convert the measured dc current-voltage (I-V) characteristics containing the self-heating effects to the isothermal I-V characteristics needed for the large-signal model. Large-signal pulse and sinusoidal input signals are used to verify the model by measurement, and shown to reproduce the observed large-signal behavior of the devices with great accuracy, especially when two or more thermal time constants are used.
Cook over IP: Adapting TCP for Cordless Kitchen Appliances (2018)

Cordless kitchens are the next big step in Smart Kitchens that are enabled by the Internet of Things (IoT) paradigm. The appliances in a cordless kitchen are powered by inductive power sources (PTx) that are integrated into kitchen counter-tops. The appliance and the PTx exchange control information using a near-field communication (NFC) channel. These appliances currently do not have Internet connectivity to enable smart cooking and control of the appliance from smartphones. Embedding a WiFi radio powered by batteries on the appliance is undesirable as batteries require recharging or replacement, and also increase the cost of the appliance. Therefore, we propose to connect the PTx to Internet and exploit the NFC channel for tunneling Internet traffic to the appliances. Due to the heavy magnetic fields induced by the PTx, this NFC channel has to be time-slotted, which is unique to the cordless kitchen appliances. This introduces many challenges on the communication, as the low data rates and high latencies of the NFC channel are aggravated by the slotting of the NFC channel. We focus on the TCP protocol as it is the most widely used transport protocol on the Internet. The performance of TCP is severely affected due to the time-slotted NFC channel. We identify two major problems that occur when TCP/IP is tunneled over the time-slotted NFC channel, namely spurious retransmissions of the TCP packets and packet drops at the NFC interface. Since most of the TCP/IP sessions in this environment are short, relying on TCP's natural course to adapt to long delays is not viable. To solve these, we propose a method to determine optimal TCP retransmission timeout values, and a channel sensing mechanism to avoid packet drops. In addition, we perform a detailed analysis to study the influence of parameters such as the contention window size, maximum segment size and NFC bit error rates. We implement and evaluate the solutions on a cordless kitchen testbed. We find that the proposed solutions almost completely eliminate the spurious retransmissions and packet drops. Furthermore, we achieve up to 53% lower end-to-end latency at 24 kbps in the NFC time-slotted mode.
Cyclophosphamide, vincristine, adriamycin, and DTIC (CYVADIC) combination chemotherapy for the treatment of advanced sarcomas. (1980)

One hundred and forty adult patients with advanced sarcomas (125 soft tissue and 15 bone) were treated with a combination chemotherapy regimen consisting of cyclophosphamide, vincristine, Adriamycin, and DTIC (CYVADIC). There were 21 (15%) complete and 45 (32%) partial responders, with an overall response rate of 47%. The response rate was 50% (17% complete) for patients with soft tissue sarcomas compared with 20% (none complete) for patients with bone sarcomas. The median duration of response was 9.5 months (range, 1-40+ months) for complete responders and 7 months (range, 1-31 months) for partial responders. The median time to achieve response was 9 weeks and the median number of courses of therapy to response was three. The median survival time was 16 months for responders compared with 7 months for nonresponders (P = 0.001). The most responsive tumor types were neurofibrosarcoma, rhabdomyosarcoma, leiomyosarcoma, fibrosarcoma, and angiosarcoma. Pulmonary and soft tissue metastases were more responsive than bone and liver metastases. CYVADIC toxicity was predominantly limited to myelosuppression, vomiting, fever of unknown origin, and neuropathy. CYVADIC is an effective combination chemotherapy regimen in the treatment of advanced sarcomas.
Serum levels of a human lung tumor-associated antigen using an improved radioimmunoassay. (1983)

A human lung tumor-associated antigen, previously purified to apparent homogeneity from an extract of a small cell tumor, was radioiodinated with Bolton-Hunter reagent for use in a competitive protein-binding radioimmunoassay. A panel of 215 sera was assembled from normal individuals and pretreatment patients with lung cancer, benign lung disease, and nonlung cancers, and lung tumor antigen in each was quantitated using the radioimmunoassay. The mean of normals was 0.92 +/- 0.43 (S.D.) microgram/ml (n = 88), and values greater than 2 standard deviations above the mean (1.78 micrograms/ml) were considered positive. Positive rates in lung cancers of the following histological types were found: adenocarcinoma, 60% (9 of 15); squamous cell, 42% (13 of 31); large cell, 17% (3 of 18); and small cell, 19% (3 of 16). In addition, 13% (3 of 23) of other cancers, 0% (0 of 24) of benign lung disease, and 2% (2 of 88) of normals were positive. Approximately one-third of Stage 1 patients in the squamous cell and adenocarcinoma groups were positive while two-thirds of patients with more advanced Stage III disease in these categories showed elevations.
Current-controlled group delay using a semiconductor Fabry–Perot amplifier (2004)

We present a demonstration of a current-controlled group delay using a semiconductor waveguide Fabry–Perot optical amplifier operated in reflection. Current injection allows us to tune the resonant wavelength as well as provide the gain required for all-pass reflection, which leads to group delay tunability with relatively small power variation. We show very good agreement between our experimental data and theoretical results, which are analogous to waveguide-coupled active ring resonators.
Recombinant Thermostable AP Exonuclease from Thermoanaerobacter tengcongensis: Cloning, Expression, Purification, Properties and PCR Application (2013)

Apurinic/apyrimidinic (AP) sites in DNA are considered to be highly mutagenic and must be corrected to preserve genetic integrity, especially at high temperatures. The gene encoding a homologue of AP exonuclease was cloned from the thermophilic anaerobic bacterium Thermoanaerobacter tengcongensis and transformed into Escherichia coli. The protein product showed high identity (80%) to human Ape1 nuclease, whereas to E. coli exonuclease III - 78%. This is the first prokaryotic AP nuclease that exhibits such high identity to human Ape1 nuclease. The very high expression level (57% of total soluble proteins) of fully active and soluble His6-tagged Tte AP enzyme with His6-tag on C-terminal end was obtained in Escherichia coli Rosetta (DE3) pLysS. The active enzyme was purified up to 98% homogeneity in one chromatographic step using metal-affinity chromatography on Ni(2+)-IDA-Sepharose resin. The yield was 90 mg (14000 kU) of pure His6-tagged Tte AP (153 kU/mg) from 1 liter of culture. The optimal conditions of Tte AP endo-, exonuclease and 3'-nuclease activity were investigated using fluorescein labeled dsDNA with inserted AP sites and ssDNA. Optimal Tte AP endonuclease activity was observed at 70-75 degrees C, pH 8.0 and at low Mg2+ concentration (0.5 mM). Higher Mg2+ concentration (> 1 mM) enhanced 3'-5' exonuclease activity and at Mg2+ concentration > 2.0 mM 3' nuclease activity was observed. Because of the endonuclease activity of Tte AP exonuclease, the enzyme was applied in PCR amplification of long DNA templates. Tte AP exonuclease eliminated AP-sites in DNA template and improved the efficiency of DNA amplification.
Isospin Effect on Pre-Scission Particle Emission (2003)

The isospin effect of particle emission for fissioning isobaric sources of 212Tl, 212Po and 212Fr and for isotopic sources of 189,202,212Po are explored in the framework of the Smoluchowski equation. The multiplicity of emitted particles shows a strong dependence on the isospin of the fission sources. Similar results are also observed for light fissioning isobaric sources of 110Tc, 110Pd and 110In and for isotopic sources of 110,117,124In. This indicates that the effect of isospin on the emission of particles is independent of the size of the fissioning system. It has been found with the increase of the isospin of heavy fissioning systems, the emission of charged particles is not sensitive to the viscosity strength. In addition, an Er isotopic chain is used to study the effects of isospin on pre-scission particle emission for various mass-asymmetric fission processes with a statistical model modified to include dissipation effects in fission. Calculations show that with the increase of the isospin of the Er nucleus, neutron emission increases, while the multiplicities of protons and α particles decrease. Again, we note that when the isospin in the fissioning system reaches a certain value, light charged particle multiplicities are no longer dependent on the fission time scale, which means that for systems of very high isospin, protons and α particles cannot be employed as probes of dissipation in fission.
Pharmacokinetic Equivalence of a Levothyroxine Sodium Soft Capsule Manufactured Using the New Food and Drug Administration Potency Guidelines in Healthy Volunteers Under Fasting Conditions (2011)

The levothyroxine soft capsule formulated with the stricter new potency guideline set forward by the Food and Drug Administration met equivalence criteria in terms of rate and extent of exposure under fasting conditions to the reference tablet formulation. Clinical doses of the capsule formulation can be given using any combination of the commercialized strengths.
Industry assessment of MINOS mine-monitoring system (1987)

This report describes the installation and operation of a computer-based belt-monitoring and control system at the Barnes and Tucker Coal Co. Mine No. 20 in Ebensburg, PA. The system installed was the National Coal Board's Mine Operating System (MINOS) coal transport monitoring and control system. The program objective was to document (1) the installation requirements for a conveyor control system, (2) the operating experience with the system, and (3) the impact of monitoring and control on mine operation.
A Concept of Idiopathic Scoliosis Deformities as Imperfect Torsion(s) (1999)

Scoliosis is a complex three-dimensional deformity. With continued improvement in spinal implant design, the options for corrective load application have increased. Visualization of the scoliosis deformity as a torsion or torsions, similar to an elongated helical line, and integration of this visualization with current deformity classification have proven useful in developing instrumentation sequences addressing scoliosis as a three-dimensional deformity. These instrumentation sequences, which have been evolving since 1989, have been applied in more than 150 patients who show improved deformity correction without serious complications.
Progressive restriction of antigen binding by human foetal thymus lymphocytes. (1976)

The proportion of foetal thymus lymphocytes (FTL) that binds the bacterial antigens beta-galactosidase and flagellin is high in early foetal life. Binding of beta-galactosidase, and the response by FTL in mixed lymphocyte culture falls during gestation. Some FTL bound both antigens, suggesting that immature lymphocytes are not fully restricted in their capacity to recognize antigens. Such findings have been reported in foetal lymphocytes from other species. We suggest that cellular diversity may partly be generated by progressive restriction of antigen recognition by individual lymphocytes, which may result from progressive stabilization of genetic repression during lymphocyte multiplication.
Designing F# Libraries (2015)

This book deals with F#, a functional-first language situated in a broader context of software construction and engineering. As an expert F# programmer, you need more than knowledge of the F# language; you also need to wisely use a range of software-engineering tools and methodologies to build software that is truly valuable for the situation in which it’s deployed. The previous chapter touched on some important tools. This final chapter will look at some of the methodological issues related to F# library design, including the following:
Lipase catalyzed synthesis of silicone polyesters (2009)

Immobilized Candida antarctica lipase B (CALB) was successfully employed as a catalyst to synthesize silicone aromatic polyesters by the transesterification of dimethyl terephthalate with alpha,omega-bis(hydroxyalkyl)-terminated poly(dimethylsiloxane) in toluene under mild reaction conditions.