gebhart/patrepeval huggingface dataset:
A high-Q tunable micromechanical capacitor with movable dielectric for RF applications (2002)

A high-Q, tunable, micromechanical capacitor has been realized using an IC-compatible, electroplated-metal surface micromachining technology and demonstrated with quality (Q-) factors in excess of 290-the highest reported to date for on-chip tunable capacitors at frequencies near 1 GHz. The key feature in this design that makes possible such high on-chip Q is the method for capacitive tuning, which in this design is based on moving the dielectric between the capacitor plates, rather than moving the plates themselves, as done in previous designs. One version of this design achieves a measured Q of 291 at 1 GHz (C=1.21 pF) with a tuning range of 7.7% over 10 V of control voltage, and an expected self-resonant frequency (SRF) of 19 GHz. In another design, with a wider tuning range of 40% over 10 V, a Q of 218 is achieved at 1 GHz (C=1.14 pF).
Plasma Apelin is Lower in Patients with Elevated LDL-Cholesterol (2007)

Hypercholesterolemia is a major risk factor for atherosclerosis. Dysregulation of adipokines contribute to atherosclerotic diseases. Apelin has recently been shown to be secreted by the adipose tissue in association with hyperinsulinemia and inflammation. We searched plasma apelin levels in patients with elevated low density lipoprotein (LDL)-cholesterol having no additional disorder. Thirty-three patients with hypercholesterolemia and 50 age-, sex-, and body mass index-matched healthy controls were evaluated for their apelin, adiponectin and high sensitivity C-reactive protein (hsCRP) levels, and homeostasis model assessment (HOMA) indexes. Plasma apelin-12 and adiponectin were determined by ELISA and RIA, respectively. Plasma apelin levels were lower in patients with elevated LDL-cholesterol compared to healthy controls (p<0.001). Plasma adiponectin concentration was also lower in the dyslipidemic patients (p<0.001). hsCRP levels were similar in the two groups. Fasting plasma glucose was normal in both groups. HOMA indexes in the dyslipidemic group were higher than the controls (p=0.005). A mild to moderate negative correlation with HOMA and positive correlation with high density lipoprotein cholesterol of apelin was found in the dyslipidemic group. Plasma apelin is decreased in non-obese, non-diabetic and normotensive patients with elevated LDL-cholesterol. Low apelin levels in hypercholesterolemia seem associated with insulin resistance, which needs to be investigated in larger populations as well as in other atherosclerotic conditions.
Reversible Carbon Monoxide Binding and Inhibition at the Active Site of the Fe-Only Hydrogenase (2000)

Carbon monoxide binding and inhibition have been investigated by electron paramagnetic resonance (EPR) spectroscopy in solution and in crystals of structurally described states of the Fe-only hydrogenase (CpI) from Clostridium pasteurianum. Simulation of the EPR spectrum of the as-isolated state indicates that the main component of the EPR spectrum consists of the oxidized state of the "H cluster" and components due to reduced accessory FeS clusters. Addition of carbon monoxide to CpI in the presence of dithionite results in the inhibition of hydrogen evolution activity, and a characteristic axial EPR signal [g(eff(1)), g(eff(2)), and g(eff(3)) = 2.0725, 2.0061, and 2.0061, respectively] was observed. Hydrogen evolution activity was restored by successive sparging with hydrogen and argon and resulted in samples that exhibited the native oxidized EPR signature that could be converted to the reduced form upon addition of sodium dithionite and hydrogen. To examine the relationship between the spectroscopically defined states of CpI and those observed structurally by X-ray crystallography, we have examined the CpI crystals using EPR spectroscopy. EPR spectra of the crystals in the CO-bound state exhibit the previously described axial signal associated with CO binding. The results indicate that the addition of carbon monoxide to CpI results in a single reversible carbon monoxide-bound species characterized by loss of enzyme activity and the distinctive axial EPR signal.
Modeling and design of a ultraviolet disinfection reactor for air recirculation systems (2010)

It is well established that many pathogenic microorganisms can reside in water. Similarly, many microbial pathogens can be suspended in air. However, disinfection processes for air are generally not as well developed as those for water. In situations involving groups of people in confined space, such as class rooms, surgery rooms, and airplane cabins, a shared air space provides opportunities for disease transmission. To reduce the danger of infections transmitted from one person to another, the addition of UV treatment in an air recirculation system may be employed. With this in mind, the primary goal of this research was to evaluate and develop an effective UV disinfection system for a recirculating air system. The specific focus will be an aircraft cabin air; however, it is expected that the principles that govern the design of this system will extend to other applications. This objective was met by first developing biodosimetry for evaluating reactor efficiency. A second step in the process of developing this system was to examine various reactor/systems by numerical modeling. Laboratory experiments involved measurements of UV dose-response behavior for several airborne microorganisms. These experiments involved a range of non-pathogenic microorganisms as surrogates for airborne microbial pathogens; Bacillus subtilis spores and coliphage MS2. These microorganisms were grown in pure cultures, and were selected to mimic the range of characteristics that represent airborne pathogens in confined space. UV dose-response behavior of these microorganisms was measured as a function of relative humidity. Various reactor geometries were evaluated by a process of numerical prototyping, which involved the combined application of computational fluid dynamics (CFD) and radiation intensity (I) field models. The effects of UV-based treatment on microbial air quality were also examined mathematically. The objective of this modeling effort was to develop a reactor system that satisfies the constraints imposed by an aircraft cabin environment. The feasible reactor system for aircraft cabin recirculation system was designed in this effort, based on the power and space requirements needed to deliver germicidal UV doses that are likely to be effective for control of airborne pathogenic microorganisms. Designed reactors may be used in other applications for air recirculation system.
Sister chromatid exchange induction by diaziquone in human and mouse lymphocytes following both in vivo and in vitro exposures. (1988)

Diaziquone (AZQ) (NSC 182986), a lipid-soluble benzoquinone derivative currently being tested as an experimental chemotherapeutic agent, was used to treat mouse and human peripheral blood lymphocytes (PBLs) to determine its genotoxic potential by examination of sister chromatid exchange (SCE) induction. In vitro exposure to AZQ caused a linear increase in SCE in both mouse and human PBLs, with mouse PBLs being about twice as sensitive as the human cells. The lowest in vitro concentration found to induce a significant effect on SCE frequency was 0.3 micrograms/ml in mice and 1.0 micrograms/ml in human PBLs. Mice exposed by either i.p. or i.v. injection showed similar dose-related linear increases in SCE frequencies in their PBLs. After i.v. administration of AZQ, splenocytes from treated mice showed approximately the same SCE frequency as found in the PBLs. In general, AZQ caused a slowing of cell cycling in vivo while giving inconsistent responses in vitro. AZQ did cause a dose-related decrease in the number of recoverable mononuclear lymphocytes in mice treated in vivo. Contrary to the in vitro studies, comparison of SCE responses in mice with those previously observed in brain tumor patients undergoing chemotherapy with AZQ (Kligerman et al., Cancer Res., 47: 631-635, 1987) revealed AZQ was a much more potent SCE inducer in humans than in mice.
Flexible spike timing of layer 5 neurons during dynamic beta oscillation shifts in rat prefrontal cortex (2009)

Human brain oscillations occur in different frequency bands that have been linked to different behaviours and cognitive processes. Even within specific frequency bands such as the beta- (14-30 Hz) or gamma-band (30-100 Hz), oscillations fluctuate in frequency and amplitude. Such frequency fluctuations most probably reflect changing states of neuronal network activity, as brain oscillations arise from the correlated synchronized activity of large numbers of neurons. However, the neuronal mechanisms governing the dynamic nature of amplitude and frequency fluctuations within frequency bands remain elusive. Here we show that in acute slices of rat prefrontal cortex (PFC), carbachol-induced oscillations in the beta-band show frequency and amplitude fluctuations. Fast and slow non-harmonic frequencies are distributed differentially over superficial and deep cortical layers, with fast frequencies being present in layer 3, while layer 6 only showed slow oscillation frequencies. Layer 5 pyramidal cells and interneurons experience both fast and slow frequencies and they time their spiking with respect to the dominant frequency. Frequency and phase information is encoded and relayed in the layer 5 network through timed excitatory and inhibitory synaptic transmission. Our data indicate that frequency fluctuations in the beta-band reflect synchronized activity in different cortical subnetworks, that both influence spike timing of output layer 5 neurons. Thus, amplitude and frequency fluctuations within frequency bands may reflect activity in distinct cortical neuronal subnetworks that may process information in a parallel fashion.
Pd(II) and Pt(II) Complexes of 2-Phenyl- and 2-Benzyl‐imidazoline: Synthesis, Structural Characterization, DNA Modification and in vitro Antileukaemic Activity (1997)

In this paper we describe the synthesis and chemical characterization of three new Pd(II)–imidazoline complexes: [PdCl2 (C6H5–CH2–C3H5N2)2] (2), [PdCl(SEt2) (C6H4-C3H5N2)] (5) and [Pd(C6H4-C3H5N2) (μ-Br)]2 (6). We have also analyzed the DNA modifications and in vitro antileukaemic activity of these compounds and of their previously reported analogs [Pd Cl2 (C6H5–C3H5N2)2] (1), [Pd (C6H4–C3H5N2) (μ-OAc)]2 (3), [Pd (C6H4–C3H5N2) (μ-Cl)]2 (4) and [Pt(C6H4–C3H5N2)(μ-Cl] (7). All these compounds modify the DNA secondary structure since they alter the melting temperature (Tm) of the DNA. Circular dichroism spectra indicated, moreover, that compounds 3, 5 and 6 induced higher modification on the double helix than compounds 1, 2 and 4. While compounds 1, 2 and 5 seem to induce slight changes in the electrophoretic mobility of the open and covalently closed circular forms of pUC8 DNA at high ri (input molar ratio of Pd or Pt to nucleotides), compounds 3, 6 and 7 do not modify at any ri the tertiary structure of the plasmid DNA. Antileukaemic tests suggest that compounds 1, 4 and 7 exhibit important cytotoxic activity since their IC50 values against HL-60 human leukaemic cells were below 10 μg ml−1. © 1997 John Wiley & Sons, Ltd.
A Hardware Accelerator for Context-Based Adaptive Binary Arithmetic Decoding in H.264/AVC (2005)

We propose a hardware accelerator for context-based adaptive binary arithmetic decoding (CABAC) in H.264/AVC. We also propose an efficient memory system for easy integration with other components such as motion compensation and IDCT. We develop an efficient finite state machine so that our design can generate one bit every 2 to 3 clock cycles. Experimental result with FPGA prototyping shows that our design is sufficient to decode main profile CIF video streams at 30 fps.
Absatz (1994)

Die Großhandelsgesellschaft ABC Leuchten mbH, München, Absatz verfügt gemäß ihrem Organisationsplan über eine Abteilung Marketing „Absatz“ und eine Abteilung „Marketing“.
Reducing the Diameters of Computer Networks (1986)

We discuss three methods of reducing the diameters of computer networks by adding additional processor to processor links under the constraint that no more than one I/O port be added to each processor. This is equivalent to adding edges to a given graph under the constraint that the degree of any node be increased, at most, by one.
Automated classification of gastric neoplasms in endoscopic images using a convolutional neural network (2019)

The evaluated deep-learning models have the potential for clinical application in classifying gastric cancer or neoplasm on endoscopic white-light images.
Programmed cell death (apoptosis) and response to anti-cancer drugs (1994)

Programmed cell death (apoptosis) is a conserved, natural mechanism for the removal of redundant and unwanted cells during normal development. This article reviews the evidence that apoptosis may also control the response of tumor cells to treatment with cytostatic drugs. Whereas most clinically used anti-cancer drugs can activate late events of apoptosis (DNA degradation and morphological changes) there are differences in essential signalling pathways between pharmacological cell death and the physiological induction of an active suicide programme. However, deregulation of normally integrated cell cycle progression appears a central signalling event in most forms of apoptosis, linking cell cycle control, DNA repair and cell death. Whether apoptosis is the cause or the consequence of drug-induced cell death remains to be established.
Piezoelectricity of chiral polymeric fiber and its application in biomedical engineering (2008)

Poly-L-lactic acid (PLLA), which is a type of chiral polymer, exhibits a high shear piezoelectric constant. To realize a higher shear piezoelectric constant, we spun PLLA resin into fibers. We succeeded in controlling the piezoelectric motion of a PLLA fiber by applying a dc voltage and ac voltage, similar to the control of a piezoelectric actuator. On the basis of this experimental result, we designed a catheter using a PLLA fiber (PLLA fiber catheter) and tweezers using a pair of PLLA fibers (PLLA fiber tweezers), controlled by adjusting the applied voltage. Then, using the PLLA fiber tweezers or catheter, we successfully picked up and removed small samples, such as a thrombosis in a blood vessel.
Equity Market Integration and Portfolio Decisions: A Study of NASDAQ USA and MSCI Emerging Markets Asia Indexes (2021)

This article studies market integration among the MSCI Emerging Markets Asia Index and the NASDAQ Composite Index for the United States of America (USA) with respect to the 2008 Global Financial Crisis. The study uses a three-level methodology based on short-term integration, long-term integration, and portfolio decisions. The correlation and Granger causality find short-term integration among the majority of the markets. According to the results of the cointegration test and value-at-risk (VAR) analysis, long-term integration exists among the markets in the post–Global Financial Crisis period. The outcome of the portfolio risk-return analysis indicates that investors have many portfolio options where investment diversification can yield better returns and lower levels of risk compared to investing only in the Indian market. Investors can make portfolio diversification decisions based on the integration among markets. Investors can generate better Sharpe ratios with diversification in both the pre-crisis and post-crisis periods. The government and policymakers can apply this information to draft decisions on monetary and economic policies. In addition, multinational companies can design their investment policies after considering integration among their markets. <b>TOPICS:</b>Mutual funds/passive investing/indexing, statistical methods, emerging markets, VAR and use of alternative risk measures of trading risk <b>Key Findings</b> ▪ The markets have become more integrated after the Global Financial Crisis. ▪ Investment in an international market is better than investing only in the home market. ▪ Investors can diversify their funds to other markets as the diversification can result in a better Sharpe ratio.
A language-driven tool for fault injection in distributed systems (2005)

In a network consisting of several thousands computers, the occurrence of faults is unavoidable. Being able to test the behavior of a distributed program in an environment where we can control the faults (such as the crash of a process) is an important feature that matters in the deployment of reliable programs. In this paper, we present FAIL (for FAult Injection Language), a language that permits to elaborate complex fault scenarios in a simple way, while relieving the user from writing low level code. Besides, it is possible to construct probabilistic scenarios (for average quantitative tests) or deterministic and reproducible scenarios (for studying the application's behavior in particular cases). We also present FCI, the FAIL cluster implementation, that consists of a compiler, a runtime library and a middleware platform for software fault injection in distributed applications. FCI is able to interface with numerous programming languages without requiring the modification of their source code, and the preliminary tests that we conducted show that its effective impact at runtime is low.
Dissociation of the ribulosebisphosphate-carboxylase large-subunit binding protein into dissimilar subunits (1987)

The ribulosebisphosphate-carboxylase large-subunit binding protein from Pisum sativum chloroplasts is an oligomer of two types of subunit with the composition alpha 6 beta 6. These two subunits are immunologically distinct, show different partial protease digestion patterns and have different amino-terminal sequences. Leaves of Hordeum vulgare also contain an oligomeric binding protein composed of equal amounts of two types of subunit. Treatment of either P. sativum stromal extracts or purified binding protein with ATP and Mg2+ ions causes the dissociation of the oligomeric form of the binding protein to the monomeric subunits. This effect is highly specific for ATP since CTP, UTP, GTP, ADP, AMP, cyclic AMP, NADPH and pyrophosphate do not cause dissociation.
Corning and cocaine: the advent of spinal anaesthesia (2009)

The inception of spinal anaesthesia can be traced to James Leonard Corning, a New York neurologist who inadvertently administered cocaine spinal anaesthesia in 1885. In 1898 August Karl Gustav Bier, a German surgeon, pioneered the successful use of operative spinal anaesthesia in lower limb surgery. Early spinal anaesthesia was fraught with complications but through advances in aseptic technique, anaesthetic agents and equipment, the seminal work of Corning and Bier has evolved into a widely established anaesthetic modality.
CASA real-time multi-Doppler retrieval system (2007)

Doppler synthesis of 3D wind products is of great practical importance to observing and understanding severe weather features such as tornadoes and microbursts. It becomes very effective for severe weather events if this modeling can be performed in real-time. A real-time multi-Doppler retrieval system forms an important product of modern weather radar networks. Challenging constraints exists between computing performance, high data resolution, and other quality issues. This Thesis describes the implementation of the operational Real-time Multi-Doppler Retrieval System (R-MDRS) of the Center for Collaborative Adaptive Sensing of the Atmosphere Engineering Research Center (CASA ERC). The R-MDRS is seamlessly integrated into CASA's Distributed Collaborative Adaptive Sensing (DCAS) operational framework and exhibit robust performance that strikes balance between high resolution and real-time processing speeds. A detailed technical description of the CASA R-MDRS implementation is given, including design approach that builds around two core components of the tool: interpolation to a common grid and Doppler synthesis. The R-MDRS generates 3D Wind products in step with network scanning modes and has been effective at detecting convective cells and tornadic activities. Data from 2009 and 2010 weather events are presented and analyzed for evaluating processing time as well as factors that effect data accuracy. These factors include Dual-Doppler candidate pair selection, advection correction, and variations in wind calculation techniques.
Leukosialin (CD43) behavior during adhesion of human monocytic THP-1 cells to red blood cells (1997)

To understand the modulation and the behavior of glycocalyx elements during adhesion, we explored one of its components, the CD43 molecule, on human monocytic THP-1 cells exposed to cytokine stimulation and its redistribution during heterotypic adhesion to opsonized erythrocytes. First we demonstrated by immunofluorescence and immunoprecipitation that CD43 is dys-sialylated in monocytic THP-1 cells stimulated by interferon-gamma (IFN-gamma) and tumor necrosis factor alpha (TNF-alpha) and stimulation increased correlated to heterotypic adhesion. CD43 anti-adhesive effect seemed to be related to sialic acid moeties because an increase in adhesion was also induced by sialidase treatment and by monoclonal antibodies recognizing sialic acid-dependent epitopes on CD43. Second, a redistribution of CD43 molecules was observed after adhesion, resulting in the exclusion of CD43 molecules from contact areas as demonstrated by immunofluorescence and by ultrastructural immunogold localization. We therefore demonstrated in monocytic THP-1 cells that some glycocalyx molecules can be modulated by cytokines and redistributed during adhesion. These results support the concept that CD43 can regulate cell interactions.
Communications - Alkyl Derivatives of Manganese Carbonyl (1957)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCommunications - Alkyl Derivatives of Manganese CarbonylRex Closson, John Kozikowski, and T. CoffieldCite this: J. Org. Chem. 1957, 22, 5, 598Publication Date (Print):May 1, 1957Publication History Published online1 May 2002Published inissue 1 May 1957https://pubs.acs.org/doi/10.1021/jo01356a024https://doi.org/10.1021/jo01356a024research-articleACS PublicationsRequest reuse permissionsArticle Views436Altmetric-Citations98LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Distribution of Plasmid Sequences in Avian and Mammalian Strains of Chlamydia psittaci (1988)

Plasmid DNA from an avian strain of Chlamydia psittaci was purified and estimated to be 7.9 kb in size using restriction endonuclease analysis. A 5.9 kb fragment of this plasmid was cloned, mapped and used to screen a range of chlamydial strains. Hybridizing DNA was absent from ovine abortion and arthritis isolates and also from the Cal 10 strain but related sequences were detected in C. psittaci strains of feline pneumonitis, guinea-pig inclusion conjunctivitis, ovine conjunctivitis and C. trachomatis serovar L2. The plasmid DNA from the feline strain was shown to have a distinct restriction endonuclease profile. Similar plasmid sequences were detected in all avian isolates tested: thus the clone may have a useful diagnostic role for the detection of the pathogen in its natural host and in zoonotic episodes.