gebhart/patrepeval huggingface dataset:
Highly selective enantiomer differentiation in intramolecular cyclopropanation reactions of racemic secondary allylic diazoacetates. (1995)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTHighly selective enantiomer differentiation in intramolecular cyclopropanation reactions of racemic secondary allylic diazoacetates.Michael P. Doyle, Alexey B. Dyatkin, Alexey V. Kalinin, Daniel A. Ruppar, Stephen F. Martin, Mark R. Spaller, and Spiros LirasCite this: J. Am. Chem. Soc. 1995, 117, 44, 11021–11022Publication Date (Print):November 1, 1995Publication History Published online1 May 2002Published inissue 1 November 1995https://pubs.acs.org/doi/10.1021/ja00149a031https://doi.org/10.1021/ja00149a031research-articleACS PublicationsRequest reuse permissionsArticle Views646Altmetric-Citations83LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (2)»Supporting Information Supporting Information Get e-Alerts
Penetrating Injuries of the Heart (1983)

This 2-year retrospective study of penetrating heart injury comprises 125 hospitalized patients (HP) (stab wounds) and 407 who died before arrival (DBA) (23 bullet, 384 stab wounds). The cardiac penetration sites were related approximately to the location of the entrance wound. The incidence of injury to respective intrapericardial structures related to their anatomic vulnerability; coronary artery transection was uncommon, however. Aortic lacerations caused rapid death (93% were DBA), followed by those breaching the left ventricle; atrial wounds comprised a greater proportion in HP than DBA series. Cardiac tamponade was more than twice as common in HP than DBA cases. Above all traditional signs, a high index of suspicion was an essential element in diagnosing heart injury; all such cases underwent thoracotomy without delay. Mortality results were: 14.4% for operating theater (OT) and 87.5% for emergency room (ER) thoracotomies. Prognosis amongst HP was worst for aortic (60% mortality) and best with right ventricular injury (7.5%). A 'salvage rate' of 17.1% overall, or 17.9% for stab wounds, was recorded.
ChemInform Abstract: Pd‐Arylurea Complexes for the Heck Arylation of Crotonic and Cinnamic Substrates. (2013)

Abstract The catalyst system shows an unusual preference for deactivated, electron‐rich aryl iodides.
The Mechanism of Jet Disintegration (1949)

Abstract : An attempt was made to develop a theory about the mechanism of jet disintegration in order to derive mathematical relations for computing droplet sizes produced by insecticide spray equipment. The most important value for calculating the droplet sizes resulting from the disintegration of a liquid jet is the wave length originating in the liquid jet as a consequence of its instability.
A Putative Mammalian RNA Helicase with an Arginine-Serine-rich Domain Colocalizes with a Splicing Factor (1995)

We have cloned a rat cDNA whose deduced primary structure yields a protein of 117.4 kDa. Because this protein contains RNA helicase consensus motifs, among them a "DEAD" box, we have termed it HEL117 (for helicase of 117.4 kDa). Besides the helicase consensus motifs, HEL117 contains an arginine-serine (RS)-rich domain, which occurs in some proteins involved in RNA splicing. Moreover, the COOH-terminal region of 78 residues of HEL117 is 38.5% identical and 59% similar to the COOH-terminal region of a yeast PRP5 protein that is involved in RNA splicing. Rabbit antibodies generated against a synthetic peptide of HEL117 identified a single polypeptide not only in rat cells but also in cells of other mammals as well as chicken. The antibodies revealed a finely punctate and speckled intranuclear staining in immunofluorescence microscopy. A monoclonal antibody against a human splicing factor containing an RS domain (SC35) showed, in double immunofluorescence microscopy, largely overlapping staining consistent with HEL117 being involved in RNA splicing.
Vehicle Lateral Dynamics Stabilization Using Active Suspension (2008)

The paper deals with the investigation of active nonlinear suspension control in order to stabilize the lateral vehicle\nmotion in similar way as systems like ESP do. The lateral stabilization of vehicle based on braking forces can\nbe alternatively provided by the different setting of suspension forces. The basis of this control is the nonlinear\nproperty of the tyres. The vehicle has at least four wheels and it gives one or more redundant vertical forces that\ncan be used for the different distribution of vertical suspension forces in such a way that resulting lateral and/or\nlongitudinal forces create the required correction moment for lateral dynamic vehicle stabilization.
Intracerebral hematoma from aneurysm rupture (2003)

Intraparenchymal hematoma in association with SAH does not differ significantly from those patients without associated hematomas. We therefore recommend aggressive clot evacuation and aneurysm obliteration.
Eating Behaviors and Dietary Changes in Patients With Dementia (2016)

Individuals with dementia frequently develop serious feeding difficulties and changes in eating and dietary habits. The changes may be secondary to cognitive impairment or apraxia, or the result of insufficient caregiving, or the consequence of metabolic or neurochemical abnormalities occurring as part of the dementing process.
Intelligent User Interface of Smartphones for On-vehicle Information Devices (2014)

The current technological trend in automotive navigation systems is toward “Display Audio” systems connected to a smartphone. However, there are some issues stemming from the differing life cycles of on-vehicle information devices and smartphones. Therefore, we expect that Display Audio will result in simple I/O devices connected via smartphones and a car-based network (e.g., Controller Area Network). However, there are numerous situations when it is necessary for a driver to easily and safely operate on-vehicle information devices. In this paper, we first discuss various types of on-vehicle information devices, and their intended use in driving situations. Second, we discuss the relation of those situations to various on-vehicle information applications. Third, we propose a simple user interface (UI) for connecting on-vehicle information devices. To conclude, we discuss the UI for on-vehicle information devices, based on context-aware technologies.
Magnetic Resonance Imaging in a Patient with Soft Tissue Sarcoma of the Leg (1985)

A patient with a high grade malignant fibrous histiocytoma of the leg is presented. Staging studies included a 99mTc diphosphonate bone scan, an arteriogram, a computed tomogram (CT) and a proton (1H) magnetic resonance imaging (MRI) study. By manipulating imaging parameters to enhance contrast between normal and neoplastic tissues, the latter technique more accurately delineated the extent of the soft tissue sarcoma than the other imaging modalities. Although spatial resolution of MRI is inferior to that of CT, it is likely that MRI will provide important information relative to surgical staging and preoperative planning that is not available from current imaging techniques.
Transport to the vacuole: receptors and trans elements (1998)

Most proteins that are synthesized on membranebound ribosomes are transported through the Golgi and reach the trans-Golgi network to be sorted for delivery to various cellular destinations, including the vacuole. Sorting involves a recognition of proteins by receptors and the assembly of cytosol-oriented coat structures that package cargo into vesicles. Vesicle trafficking is regulated by specific membrane-bound and soluble proteins. Several components of the secretory machinery have recently been identified in plants and are described in this review. Ongoing and future research will characterize features of the secretory pathway specific to plants which, because of the multiplicity of vacuole types, provide a more complex paradigm than the better described mammalian and yeast systems.
Scalable, distributed data structures for internet service construction (2000)

This paper presents a new persistent data management layer designed to simplify cluster-based Internet service construction. This self-managing layer, called a distributed data structure (DDS), presents a conventional single-site data structure interface to service authors, but partitions and replicates the data across a cluster. We have designed and implemented a distributed hash table DDS that has properties necessary for Internet services (incremental scaling of throughput and data capacity, fault tolerance and high availability, high concurrency, consistency, and durability). The hash table uses two-phase commits to present a coherent view of its data across all cluster nodes, allowing any node to service any task. We show that the distributed hash table simplifies Internet service construction by decoupling service-specific logic from the complexities of persistent, consistent state management, and by allowing services to inherit the necessary service properties from the DDS rather than having to implement the properties themselves. We have scaled the hash table to a 128 node cluster, 1 terabyte of storage, and an in-core read throughput of 61,432 operations/s and write throughput of 13,582 operations/s.
Stereoretentive Palladium‐Catalyzed Arylation, Alkenylation, and Alkynylation of 1‐Thiosugars and Thiols Using Aminobiphenyl Palladacycle Precatalyst at Room Temperature (2015)

A general and efficient protocol for the palladium-catalyzed functionalization of mono- and polyglycosyl thiols by using the palladacycle precatalyst G3-XantPhos was developed. The C-S bond-forming reaction was achieved rapidly at room temperature with various functionalized (hetero)aryl-, alkenyl-, and alkynyl halides. The functional group tolerance on the electrophilic partner is typically high and anomer selectivities of thioglycosides are high in all cases studied. New sulfur nucleophiles such as thiophenols, alkythiols, and thioaminoacids (cysteine) were also successfully coupled to lead to the most general and practical method yet reported for the functionalization of thiols.
Differential x-ray phase contrast imaging using a shearing interferometer (2002)

An x-ray interferometer has been developed that uses two transmission phase gratings to analyze wave front distortions in the hard x-ray range. The interferometer is insensitive to mechanical drift and vibrations, and it is tunable over a wide range of photon energies. This setup was used for differential phase contrast imaging of low-absorbing test objects. We obtained micrographs with moiré fringes of good visibility, which revealed the local phase shift gradient caused by the objects. A comparison with numerically simulated images indicates that quantitative analysis of unknown phase objects is possible.
Special issue from the 20th International Symposium on Alcohol Fuels (ISAF 2013): alcohol fuels enabling sustainable future development (2013)

This Editorial introduces a special issue from the 20th International Symposium on Alcohol Fuels (ISAF 2013) on alcohol fuels enabling sustainable future development.
Wrinkle dependency on web roller slip (1995)

The shear forces in a web introduced from an untrammed roller create wrinkles that are affected by web twisting or slipping on the upstream roller. The web span bounded between the untrammed and upstream rollers behaves like a beam when bending in the web plane (2). If the bending stresses exceed the capacity of the friction forces holding the web on the upstream roller, strain will migrate over the roller transferring a portion of the moment to the upstream span. A model is presented that predicts the onset of moment transfer based on equilibrium equations for a beam in bending, and web roller traction.
Influence of Nozzle geometry on spray shape, particle size, spray velocity and Air entrainment of high pressure Diesel spray (2010)

International audience
Update: Meta-analysis of Overall Risk for Lymphoma with Immunomodulators for Inflammatory Bowel Disease (2010)

Purpose: Inflammatory bowel disease (IBD) treatment includes azathioprine (AZA) and 6-mercaptopurine (6-MP), which have been implicated in increasing the risk of lymphoma approximately fourfold (Kandiel 2005 PMID: 16009685). One major limitation of this study was that referral data was combined with one population based study. The risk of lymphoma in referral centers may be artifically inflated due to sicker patients with more comorbidities (Ang 2006 PMID 16531538). Recently, an updated examination of the UK GPRD database (Armstrong 2010 PMID: 20104215) has been published. Here we updated our previous meta-analysis (Kotlyar, J Clin Onc 28, 2010 [suppl; abstr e18517]) with Armstrong, and directly compare referral center data with population based data to assess if referral bias is operant, and to assess overall risk. Methods: We searched MEDLINE for: “lymphoproliferative and thiopurines”; and “azathioprine and lymphoma”. Included citations were cohort studies examining IBD (ulcerative colitis and Crohn's disease), evaluated cancer as an outcome, and pts. received AZA and/or 6-MP. Pooled standardized incidence ratios (SIRs) and 95% confidence intervals (CIs) were estimated by summing observed and expected cases of lymphoma. Cases involving methotrexate treatment in Van Domselaar were excluded. CIs assumed a Poisson distribution. To examine for heterogeneity, the deviance statistic from Poisson regression models was examined. Results: There were 418 citations, and 412 were excluded. Two studies (Korelitz and Kinlen) were obtained from references from Kandiel 2005, and Lewis 2001 was replaced by Armstrong 2010 as data were also from the GPRD database. In referral centers (n=6), the SIR=4.66. (95% CI: 2.60-7.70). In population studies (n=2), the SIR=4.36 (95% CI: 2.69-6.67). Overall the SIR was=4.48 (95% CI: 3.13-6.20). Data from referral centers showed significant heterogeneity (p=0.047), with one study having a very high SIR and one study not observing any lymphomas. Other data showed no significant heterogeneity. There was also no significant difference between the SIRs of the two groups (p=0.84). Conclusion: Patients with IBD who are treated with thiopurines have approximately a 4- to 5-fold increased risk of lymphoma as compared to the general population. The estimated magnitude of this increased risk is similar in studies from referral centers and in population-based studies. Disclosure: Dr Lichtenstein: Abbott Corporation Consultant Alaven Consultant Bristol-Myers Squibb Research Centocor, Inc. Consultant, Research Elan Consultant Ferring Consultant, Research Millenium Pharmaceuticals Consultant Proctor and Gamble Consultant, Research Prometheus Laboratories, Inc. Consultant, Research Salix Pharmaceuticals Consultant, Research Schering-Plough Corporation Consultant Shire Pharmaceuticals Consultant, Research UCB Consultant, Research Wyeth Consultant All others: No conflict of interest.Table: [1167] Meta-analysis of Standardized Incidence Ratios (SIR)
Comparison of Intervention Technologies for Reducing Escherichia coli 0 157:H7 on Beef Cuts and Trimmings (2003)

This study evaluated the decontamination efficacy of water (W; 250 or 55°C), 2% acetic acid (M), 0.00 I % acidified chlorine (AC), 2% lactic acid (LA; 55°C), 0.02% acidified sodium chlorite (ASC), 0.5% cetylpyridinium chloride (CPC), 1% lactoferricin B (LB), and 0.02% peroxyacetic acid (PAA) on Escherichia coli 0 157:H7 when applied to fresh beef carcass tissue (BCT) surfaces (40 ern) and lean tissue pieces (LTP; 300 g). Samples were inoculated with a five-strain composite of E. coli 0 157:H7 and then immersed in the treatment solutions for 30 s. Viable cell counts were enumerated by plating on sorbitol MacConkey (SMAC) agar. Overall, CPC was most effective (P < 0.05) and reduced bacterial populations by 4.8 log CFU/cm2 and 2.1 log CFU/g on BCT and LTp, respectively. Of the treatments commonly used by industry, LA was the most effective (P < 0.05),as it reduced pathogen populations by 3.3 log CFU/cm2 and 1.3 log CFU/g on BCT and LTp, respectively. Additionally,ASC,AA, PAA, LB,AC and W reduced pathogen populations when plated on SMAC by 1.9, 1.6, 1.4,0.7, 0.4 and 1.2 log CFU/cm2, when applied to BCT, while corresponding reductions following the above treatment applications to LTP were 1.8, 1.1, 1.0, 0.4,0.5 and 0.3 log CFU/g, respectively. Results from this study indicated that LA and ASC were the most effective pathogen decontamination solutions currently approved for commercial use, Information regarding the antibacterial efficacy of decontamination solutions should prove beneficial to industry personnel as a means of improving microbiological quality as well as potentially improving the quality of non-intact beef tissue.
Improvement of vitamin B <sub>12</sub> status with <i>Spirulina</i> supplementation in Wistar rats validated through functional and circulatory markers (2019)

Spirulina evaluated as a source of vitamin B<sub>12</sub> through the modulation of vitamin B<sub>12</sub> deficiency mediated physiological and biochemical changes in experimental animals. The B<sub>12</sub> deficient male weanling Wistar rats were fed with Spirulina-supplemented diet for 10 weeks. An increase in urinary methylmalonic acid (22.70 ± 4.08 µmol/moles of creatinine) and plasma homocysteine (16.55 ± 0.48 µmol/L) levels in the B<sub>12</sub> deficient group was observed, while these were equal to control in the Spirulina fed group (8.71 ± 0.48 µmol/mol of creatinine and 6.88 ± 1.18 µmol/L, respectively). The vitamin B<sub>12</sub> levels in serum (874.27 ± 89.69), plasma (615.53 ± 26.5 pg/ml), kidney (10.19 ± 1.066 ng/g), and liver tissues (6.37 ± 0.62 ng/g) in the Spirulina fed group were similar to control. Severe atrophic changes in the testes and altered tissue architecture in lung and spleen as seen in the B<sub>12</sub> deficient group were normalized in the Spirulina fed group. The study validates that Spirulina can improve the vitamin B<sub>12</sub> status. PRACTICAL APPLICATIONS: The present study showed that the supplementation of Spirulina in the diet of vitamin B<sub>12</sub> deficient rats leads to the normalization of vitamin B<sub>12</sub> deficiency-induced circulatory and functional biomarkers along with biochemical and histological changes. Vegetarian sources for vitamin B<sub>12</sub> are limited and the results presented here provide scientific validation for the use of Spirulina as a potential vegetarian source of bioavailable vitamin B<sub>12</sub> .
Optimization of Axial Enrichment and Gadolinia Distributions for BWR Fuel under Control Rod Programming, (II) (1992)

A method has been developed for optimizing the axial enrichment and gadolinia distributions for the reload BWR fuel under control rod programming. The problem was to minimize the enrichment requirement subject to the criticality and axial power peaking constraints. The optimization technique was based on the successive linear programming method, each linear programming problem being solved by a goal programming algorithm. A rapid and practically accurate core neutronics model, named the modified one-dimensional core model, was developed to describe the batch-averaged burnup behavior of the reload fuel. A core burnup simulation algorithm, employing a burnup-power-void iteration, was also developed to calculate the rigorous equilibrium cycle performance. This method was applied to the optimization of axial two- and 24-region fuels for demonstrative purposes. The optimal solutions for both fuels have proved the optimality of what is called burnup shape optimization spectral shift. For the two-region fuel with a practical power peaking of 1.4, the enrichment distribution was nearly uniform, because a bottom-peaked burnup shape flattens the axial power shape. Optimization of the 24-region fuel has shown a potential improvement in BWR fuel cycle economics, which will guide future advancement in BWR fuel designs.
Comparison of Gynecologic History and Laboratory Results in HIV-Positive Women With CD4+ Lymphocyte Counts Between 200 and 500 Cells/μl and Below 100 Cells/μl (1999)

Gynecologic complications are common among HIV-seropositive women with CD4+ lymphocyte counts < 500 cells/microl and are more common and severe among those with more advanced immunosuppression.
River Analyzer for Chlorotriazines with a Direct Optical Immunosensor (1999)

An optical immunosensor coupled to a FIA system was evaluated to monitor chlorotriazine pesticides in river water samples. The assay is based on a solid-phase fluorescence immunoassay with immobilized analyte derivative and free, fluorescence-labeled anti-atrazine or anti-simazine antibodies. The response of the immunoprobe in the presence of cross-reactants structurally similar to atrazine (simazine, deisopropylatrazine, and deethylatrazine) was studied. Limits of detection for atrazine and simazine varied between 0.06 and 0.2 μg L-1, depending if Milli-Q water or river water samples were used. Monitoring of river water samples in the Ebre area (Tarragona, Spain) during 3 months was carried out. Eighteen measurements were carried out, and only eight samples could be detected with simazine and atrazine levels ranging from 0.18 to 1 μg L-1. The results obtained with the immunosensor were validated by chromatographic techniques. The 50-mL water samples were preconcentrated by on-line solid-phase extraction (SPE) followed by liquid chromatography−atmospheric pressure chemical ionization−mass spectrometry (LC−APCI−MS). In this way, unequivocal confirmation of the environmental levels of the Ebre samples was accomplished. This RIver ANAlyzer (RIANA) with an optical immunosensor can be applied for the monitoring of chlorotriazines in river water samples with a total analysis time of 15 min. No false positive was detected.
Rational Electrolyte Modification of n ‐ CdSe /  (  [ KFe (  CN  ) 6 ] 3 −  / 2 −  )  Photoelectrochemistry (1992)

Cyanide effects on photoelectrochemical cells (PECs) result in the highest solar to electrical conversion efficiency for a PEC. We report that appropriate solution modification stabilizes not only photoelectrode, but also the photoelectrolyte, against decomposition. We also investigate a suggestion that a substantial fraction of this efficiency and 26% of the observed photocurrent was due to a "virtual battery" resulting from electrochemical discharge of cyanide, rather than the photoinduced oxidation of ferrocyanide. This battery effect is not observed at either Pt or PEC systems, and results supporting that effect are simple artifacts of the experimental configuration in that study.
ChemInform Abstract: Synthesis and Reactivity of Pyrrolo(1,2‐a)quinoxalines. Crystal Structure and AM1 Calculation. (1995)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.