gebhart/patrepeval huggingface dataset:
Reaktionen des Diphenylphosphanoxids mit Organodiboranen(6) – Struktur einer zwitterionischen –POB– ‐Verbindung<sup>1)</sup> (1987)

Abstract Aus Diphenylphosphanoxid (C 6 H 5 ) 2 P(O)H ( 1 ) erhält man mit aktiviertem Triethylboran ( 2a *) das Derivat (C 6 H 5 ) 2 POB(C 2 H 5 ) 2 ( 3′a ). Aus 3′a sind mit Tetraalkyldiboranen(6) (R 2 BH) 2 [RC 2 H 5 : ( 4a ) 2 ; RC 3 H 7 : ( 4b ) 2 ] die BH 3 ‐Additionsverbindungen (C 6 H 5 ) 2 P(BH 3 )OBR 2 [RC 2 H 5 : 3′a –BH 3 ], [(C 6 H 5 ) 2 P(BH 3 )‐O] 2 BR [RC 2 H 5 : 5a –(BH 3 ) 2 ] und [(C 6 H 5 ) 2 P(BH 3 )O] 3 B [ 6 –(BH 3 ) 3 ] zugänglich. Bis(9‐borabicyclo[3.3.1]nona) ( 4c ) 2 und 1 reagieren unter Bildung von (C 6 H 5 )POBC 8 H 14 ( 3′c ) oder 3′c – 4c und (C 6 H 5 PH–HBC 8 H 14 ( 7 – 4c ). Das kristallisierte zwitterionische (C 6 H 5 ) 2 P(H)OB[OP(BH 3 )‐
The Total Synthesis of Cedrol and Cedrene (1955)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe Total Synthesis of Cedrol and CedreneGilbert Stork and Frank H. Clarke Jr.Cite this: J. Am. Chem. Soc. 1955, 77, 4, 1072–1073Publication Date (Print):February 1, 1955Publication History Published online1 May 2002Published inissue 1 February 1955https://pubs.acs.org/doi/10.1021/ja01609a104https://doi.org/10.1021/ja01609a104research-articleACS PublicationsRequest reuse permissionsArticle Views906Altmetric-Citations45LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Practical considerations on color image enhancement using homomorphic filtering (1997)

We present a study concerning the practical possibilities of using the homomorphic filtering for color image enhancement. Two of the most popular color models, RGB and C-Y (color difference), are employed and the results are comparatively discussed. The homomorphic filtering has proven to be a viable tool for both color models considered.
A ratiometric sensor for DNA based on a dual emission Ru(dppz) light-switch complex (2017)

Herein we describe the DNA binding properties of two new water-soluble ruthenium complexes; experimental and computational data reveal that both complexes display dual emission from MLCT and LLCT excited states. The interaction of the new complexes with DNA was also investigated. Although one of the complexes only binds DNA though groove binding, the second complex has separate ligands capable of groove binding and intercalation. Nevertheless, it was found that both complexes interact with duplex DNA with high affinity. DNA induced distinctive changes in the emission of the complexes; although the groove binding complex only displays a modest increase in emission on binding, the complex that contains the intercalating Ru<sup>II</sup>(dppz) moiety displays a large increase in MLCT-based emission on DNA binding while emission from the LLCT excited state is unaffected. This means that the complex functions as the first ratiometric sensor for DNA.
Large low field magnetoresistance in La0.67Sr0.33MnO3 nanowire devices (2011)

Large low field magnetoresistance (LFMR) of about 28% is observed in La0.67Sr0.33MnO3 nanowires with 80 nm in diameter at T=300 K. A gradual decrease in the LFMR has been found with increase in wire diameter. The LFMR drops to zero for wires above 280 nm in diameter. The nanowires are grown by means of electrospinning process and exhibit distorted orthorhombic crystal structure. The large LFMR is considered as a grain boundary effect as observed in several perovskite systems. The large LFMR observed in these manganites with reduced dimensions may be useful for room temperature device applications.
Infection with Human Immunodeficiency Virus in the Hospital (1986)

Infection with the human immunodeficiency virus (HIV) (formerly HTLV-III/LAV) is transmitted by sexual contact, by blood and blood products, and perinatally. There is no evidence for casual transmission. The risk to health care workers is low but appropriate infection control precautions should be taken. Specimens should be transported to the laboratory in plastic bags labeled with an easily recognized biohazard warning. Placing patients in private rooms is unnecessary unless a patient has an additional illness that requires such an arrangement. Disinfection, sterilization, housekeeping, and waste management must be done according to recommended guidelines. Asymptomatic hospital personnel with HIV antibody can safely engage in direct patient care. Routine HIV serologic screening of personnel or patients is not recommended. Counseling and HIV antibody testing should be offered to pregnant high-risk women. Laboratories that process specimens potentially containing HIV virus should adhere to maximum containment procedures. An intensive and continuing educational program on the epidemiology of HIV infection and appropriate infection control practice is recommended.
[Analgesia and renal insufficiency]. (2008)

Chronic kidney disease (CKD) prevalence increases with population aging and makes drugs prescription more difficult. Only a few studies have reported drug dosing adjustment in CKD patients, even in the important field of pain management. We propose an algorithm based on the current literature that helps in selecting right analgesic according to the degree of renal failure. Drug dosing adjustment of the most usually used analgesics (acetaminophen, nonsteroidal anti-inflammatory drugs and opioids) is discussed.
An element of the BK virus enhancer required for DNA replication (1989)

The human papovavirus BK virus contains three 68-base-pair (bp) repeats that act as transcriptional enhancers. An analysis of plasmids containing the BK virus origin revealed that sequences within the 68-bp enhancer are required for DNA replication as well as transcription of the early promoter in COS-1 cells. Origins with a single 68-bp repeat replicated as efficiently as did those with three repeats when transfected into COS-1 cells. Replication did not occur in the absence of enhancer sequences and could not be restored by distal placement of enhancers to enhancerless origins. However, as with simian virus 40, replication in vitro was not dependent on the presence of any enhancer sequences. Deletion analysis showed that replication of BK virus origins was dependent on the presence of the first 21 bp of the enhancer contiguous with the A-T-rich stretch of the origin. This 21-bp element is referred to as the rep element. Although in combination with rep the remaining 47 bp of the enhancer appear to increase replication by two- to fivefold, they alone are not sufficient to support replication. Deletions or insertions in the enhancer which did not alter the rep element had no major effect on replication. Site-directed mutagenesis of the Sp1-like site within the rep element, the NF1 site present in the enhancer, or the NF1 site in adjacent late-side sequences each reduced transcription by two- to fivefold, but had no effect on replication, suggesting that replication and transcription can be uncoupled.
Direct Comparison of Three Isotopic Release Microtoxicity Assays as Measures of Cell-Mediated Immunity to Gross Virus-Induced Lymphomas in Rats (1977)

Three isotopic release microtoxicity assays--[125I]5-iodo-2'-deoxyuridine release assay (IRA), 51Cr release assay (CRA), and [3H]proline release assay (PRA)--have been utilized to measure cell-mediated immunity to (C58NT)D, a Gross virus-induced lymphoma in rats. These studies were designed so that all three assays were done under physical conditions as comparable as possible between the assays. A considerable difference was noted in the ability of one or another target cell to function well in each assay. The tissue culture line of (C58NT)D proved an excellent target cell in the long-term assays, whereas the ascites line was inadequate in these same long-term assays. The monolayer Gross virus-induced tumor cell line ERTh/G was resistant to lysis in the short-term CRA but functioned well in the long-term assays. The autologous and thymus cell controls utilized in these studies were reasonably neutral baseline controls for the evaluation of both normal and immune activity. Although all three assays were capable of measuring both natural and immune activity in this systemthe PRA appeared more sensitive at 24 hours and the IRA at 48 hours, whereas the CRA activity with these target cells was only useful in the short-term assays.
Methodology to retrieve and assess the accuracy of atmospheric temperature profiles at the pixel level using satellite sounder data (1994)

In this paper, we present the first of a two part discussion to improve the specification of atmospheric transmission calculations using a new methodology to reduce the uncertainty in pixel-level temperature profiles derived from meteorological satellite sounder data. Temperature profiles are examined first, since these data are used to derive the moisture content of the atmosphere. Our results show that the uncertainty in the specification of temperature profiles, for pixel level retrievals of meteorological satellite sounder data, can be assessed using knowledge on the accuracy of the initial-guess to a physical relaxation algorithm.
DLTS method using a single temperature scanning (1981)

A method of DLTS with only one temperature raising is described and discussed. It allows to obtain the activation energy of deep trap emission probability not only from detached DLTS responses but also from partially superimposed responses. Besides it is shown that reducing the overlapping of such responses is possible. A simple and low-cost experimental arrangement is set up. Une procédure d'exploitation de la DLTS à une seule remontée de température est décrite et discutée. Elle permet d'obtenir l'énergie d'activation de la probabilité d'émission des pièges profonds non seulement pour des réponses DLTS isolées, mais aussi pour des réponses partiellement superposées. On montre d'ailleurs qu'il est possible de diminuer le recouvrement de telles réponses. Un montage expérimental simple et relativeèment peu couteux est proposé.
Le Dernier des hommes. DVD (1924)

Grâce a l'admiration de ses voisins pour son bel uniforme, un vieux portier d'hotel se prend pour une sorte de prince. Mute sans menagement au gardiennage des toilettes, sa livree lui est retiree...
Corrélation d'images volumiques : quelles limites à la résolution spatiale? (2011)

National audience
Viral and cellular factors underlying neuropathogenesis in HIV associated neurocognitive disorders (HAND) (2014)

As the HIV-1 epidemic enters its fourth decade, HIV-1 associated neurological disorders (HAND) continue to be a major concern in the infected population, despite the widespread use of anti-retroviral therapy. Advancing age and increased life expectancy of the HIV-1 infected population have been shown to increase the risk of cognitive dysfunction. Over the past 10 years, there has been a significant progress in our understanding of the mechanisms and the risk factors involved in the development of HAND. Key events that lead up to neuronal damage in HIV-1 infected individuals can be categorized based on the interaction of HIV-1 with the various cell types, including but not limited to macrophages, brain endothelial cells, microglia, astrocytes and the neurons. This review attempts to decipher these interactions, beginning with HIV-1 infection of macrophages and ultimately resulting in the release of neurotoxic viral and host products. These include: interaction with endothelial cells, resulting in the impairment of the blood brain barrier; interaction with the astrocytes, leading to metabolic and neurotransmitter imbalance; interactions with resident immune cells in the brain, leading to release of toxic cytokines and chemokines. We also review the mechanisms underlying neuronal damage caused by the factors mentioned above. We have attempted to bring together recent findings in these areas to help appreciate the viral and host factors that bring about neurological dysfunction. In addition, we review host factors and viral genotypic differences that affect phenotypic pathological outcomes, as well as recent advances in treatment options to specifically address the neurotoxic mechanisms in play.
Inflammatory bowel disease: is it really just another break in the wall?: Figure 1 (2006)

Although the critical factors necessary for IBD pathogenesis remain mysterious, interest in the potential role of defective epithelial barrier function continues to grow. New insight into the mechanisms responsible for barrier dysfunction in IBD may lead to understanding its contribution to disease development and progression.
Spatula: Efficient cross-camera video analytics on large camera networks (2020)

Cameras are deployed at scale with the purpose of searching and tracking objects of interest (e.g., a suspected person) through the camera network on live videos. Such cross-camera analytics is data and compute intensive, whose costs grow with the number of cameras and time. We present Spatula, a cost-efficient system that enables scaling cross-camera analytics on edge compute boxes to large camera networks by leveraging the spatial and temporal cross-camera correlations. While such correlations have been used in computer vision community, Spatula uses them to drastically reduce the communication and computation costs by pruning search space of a query identity (e.g., ignoring frames not correlated with the query identity’s current position). Spatula provides the first system substrate on which cross-camera analytics applications can be built to efficiently harness the cross-camera correlations that are abundant in large camera deployments. Spatula reduces compute load by $8.3\times$ on an 8-camera dataset, and by $23\times-86\times$ on two datasets with hundreds of cameras (simulated from real vehicle/pedestrian traces). We have also implemented Spatula on a testbed of 5 AWS DeepLens cameras.
Turbulent premixed combustion in a boundary layer (1984)

Abstract The turbulent boundary layer arising from the injection of cold reactants into a hot product stream is studied theoretically. By treating the rate of growth of the boundary layer as a small parameter and by assuming power law variations of global features of the layer the equations of a Reynolds stress closure are reduced to similarity form. A combination of the aerothermochemical model of premixed turbulent combustion due to Bray-Moss-Libby and standard models for pressure fluctuations and dissipation results in a closed set of equations which are solved numerically. The predictions are compared with available experimental data.
Is Consumer Electronics Redesigning Our Cars?: Challenges of Integrated Technologies for Sensing, Computing, and Storage (2018)

This article critically analyzes the trends and limits of integrated technologies for sensing, computing, and data storage when devices and systems originally developed for consumer electronics (CE) are used for self-driving cars. Some hints, supported by theoretical analysis and experimental work, are provided to overcome the issues of inertial sensors, micromirrors for lidar scanners, car data/program memory, and computing platforms.
Loss of a Protein Phosphatase 2A Regulatory Subunit (Cdc55p) Elicits Improper Regulation of Swe1p Degradation (2000)

CDC55 encodes a Saccharomyces cerevisiaeprotein phosphatase 2A (PP2A) regulatory subunit.cdc55-null cells growing at low temperature exhibit a failure of cytokinesis and produce abnormally elongated buds, butcdc55-null cells producing the cyclin-dependent kinase Cdc28-Y19F, which is unable to be inhibited by Y19 phosphorylation, show a loss of the abnormal morphology. Furthermore,cdc55-null cells exhibit a hyperphosphorylation of Y19. For these reasons, we have examined in wild-type and cdc55-null cells the levels and activities of the kinase (Swe1p) and phosphatase (Mih1p) that normally regulate the extent of Cdc28 Y19 phosphorylation. We find that Mih1p levels are comparable in the two strains, and an estimate of the in vivo and in vitro phosphatase activity of this enzyme in the two cell types indicates no marked differences. By contrast, while Swe1p levels are similar in unsynchronized and S-phase-arrested wild-type and cdc55-null cells, Swe1 kinase is found at elevated levels in mitosis-arrestedcdc55-null cells. This excess Swe1p incdc55-null cells is the result of ectopic stabilization of this protein during G2 and M, thereby accounting for the accumulation of Swe1p in mitosis-arrested cells. We also present evidence indicating that, in cdc55-null cells, misregulated PP2A phosphatase activity is the cause of both the ectopic stabilization of Swe1p and the production of the morphologically abnormal phenotype.
ChemInform Abstract: Synthesis and Properties of Bitetraselenafulvalene. (1999)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
TRANSPLANTATION ANTIGEN LEVELS IN THE EARLY MOUSE EMBRYO (1964)

Embryo cell transplantation antigens have been measured by the titration of isoantisera absorbed with allogeneic embryo cells, using a microcytotoxic test. H-2 antigens appear and increase in 9-day embryos at approximately equal rates in two of the three strains examined; results with a third strain suggest the possibility of strain-dependence of transplantation antigen development. The cells of 9-day mouse embryos are considerably less antigenic than adult lymphoid cells.
Gradient semi-interpenetrating polymer networks based on polyurethane and poly(2-hydroxyethyl methacrylate) for biomedical applications (2012)

Gradient semi-interpenetrating polymer networks (gradient semi-IPNs) as well as the traditional semi-interpenetrating polymer networks (semi-IPNs) were synthesized using polyurethane (PU) and poly(2-hydroxyethyl methacrylate) (PHEMA). The materials were characterized with respect to thermodynamic miscibility, NIR imaging, mechanical properties and morphological structure by tapping mode atomic force microscopy (TM AFM). The positive values of Gibbs free energy indicated that polymeric systems were thermodynamically immiscible. The dynamic mechanical analysis as well as TM AFM demonstrated that the systems under investigation were two-phase systems with incomplete phase separation. The gradient semi-IPNs were shown to have unique mechanical properties dependent on the composition and on the degree of microphase separation. The ability to create a layer of biocompatible polymer, such as PHEMA, at the surface, or create nanostructured surface consisting of nanodomains of different polymeric compositions, and engineer the improvements in the mechanical properties of the materials through the use of gradient systems should allow the creation of novel materials for biomedical application through the optimisation of mechanical properties, surface chemistry and biological properties.
Four-fold concentration of sucrose in sugarcane juice through energy efficient forward osmosis using sea bittern as draw solution (2015)

Clarified sugarcane juice was efficiently dewatered through the spontaneous process of Forward Osmosis (FO) employing sea bittern as draw solution.
Evaluation of school children at high risk for fragile X syndrome utilizing buccal cell FMR‐1 testing (1994)

We describe a pilot project utilizing saliva to identify the FMR-1 mutation in high-risk special education students from four public school districts in Colorado. The program included presentations to special education teachers regarding fragile X syndrome, parental consent for testing, completion of a behavior checklist by the teachers, identification of special education students at high risk for fragile X syndrome, subsequent brief examination of face and hands, collection of a saliva sample by either Gatorade swish or brushing of the inside of the cheek, and analysis for the FMR-1 mutation by PCR. Equivocal samples were studied by direct DNA testing using Southern blot analysis, and abnormal results were confirmed by a blood analysis for the FMR-1 mutation. Mutant individuals received genetic counseling and medical and educational assessments to optimize treatment and intervention. This pilot project was met with enthusiasm by the schools. Of the first 439 students evaluated, 68% were male with an average age of 7.75 years; 13% were mentally retarded or autistic. Most students referred for the evaluation were learning disabled (51%) and/or had an Attention Deficit Hyperactivity Disorder (ADHD) (35%). The overall prevalence of the FMR-1 mutation was 5 of 439 or 1.1%. This relatively low yield is probably due to the high number of non-retarded but learning disabled students tested. Of the mentally retarded patients tested, 3.5% were positive for the FMR-1 mutation; however, of the non-retarded or learning disabled patients, only 0.79% were FMR-1 positive.(ABSTRACT TRUNCATED AT 250 WORDS)
Abstract 14914: Sex-Related Differences in Aortic Stenosis: Pre-operative Hemodynamics and Correlates of Aortic Valve Weight (2014)

Introduction: Valve weight in calcific aortic stenosis (AS) is thought to be mostly secondary to calcification and female sex is associated with less calcium burden. Contemporary data describing sex-related differences in pre-operative clinical characteristics, hemodynamics, and postoperative aortic valve weight (AVW) are scarce.

Hypothesis: AVW will correlate well with CT calcium score and female sex will be associated with lower AVW even after correction for anthropomorphic and clinical factors.

Methods: Postoperative AVW was measured in 1090 consecutive patients (692 male, 398 female) with AS.

Results: Women were slightly older (74±11 vs 73±10 years, p=0.04), had more hypertension (79% vs 73%, p=0.04), slightly higher NYHA functional class (2.64±0.71 vs 2.51±0.72, p=0.004), and less coronary artery disease (39% vs 54%, p<0.0001). Women had higher ejection fraction (63±10 vs 59±12, p<0.0001) and smaller aortic valve area (0.80±0.19 vs 0.91±0.18 cm2, p<0.0001), but had a similar indexed valve area (0.44±0.09 vs 0.44±0.10 cm2/m2, p=0.49) and mean gradient (51±15 vs 49±14 mm Hg, p=0.10). In 142 patients, CT aortic valve calcium score correlated well with AVW (r=0.80, p<0.0001) and was lower in women compared to men (2400±1170 AU vs 3557±1616, p<0.0001). Univariate and multivariate discriminators of AVW can be found in table 1.

Conclusions: CT coronary calcium scoring correlates well with AVW and the major correlates of increased AVW are male sex, bicuspid valve, and increased left ventricular outflow tract size. Despite a similar severity of AS, women had less aortic valve calcium and lower AVW compared to men even after correction for other confounding variables. This may be related to a greater degree of aortic valve fibrosis than calcification in women and/or varying adaptability to AS in men versus women. Examination of potential sex-related differences in the pathophysiology of AS may be helpful in elucidating potential non-surgical targets to treat AS.

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