gebhart/patrepeval huggingface dataset:
Inter- and multi- professional (1999)

Inter-professional education and multi-professional education are both high on the NHS's agenda. For me it says we have much to learn alongside, with and from our health care colleagues. And they have much to learn from us. It is important that the recipients of this ‘inter’ and ‘multi’ learning are taught by the most expert and/or appropriate person. I would be happy to have an endoscopy performed on me by an expert endoscopy nurse, but I want that nurse trained in the necessary skills by a medical consultant. The nurse after all is providing the same level of care that I should expect from the doctor. His/her competence and accountability will be judged at the medical level.
A trial construction of a secondary electron multiplier with ring-shaped dynodes (1989)

A box-grid type of secondary electron multiplier with ring-shaped dynodes has been constructed. In this multiplier, since the area of the later dynode becomes larger, output current shows no saturation by the space-charge effect at high current (70 μA).
Dose- (and Time-) Dependent Blockade of Pregnancy in Sprague-Dawley Rats Administered Ammonium Dinitramide in Drinking Water (1996)

Ammonium dinitramide (ADN) is a class 1.1 explosive oxidizer that can be used in solid rocket propellant mixtures and explosives. A 90-day general toxicity/ reproductive screen performed on this compound at doses of 162, 103, 29, and 0.0 mg ADN/kg/day resulted in a treatment-related adverse effect on litter production. Incidences of animals producing litters (1/11, 3/12, 12/12, and 11/12, respectively) and mean numbers of pups per litter (7, 7, 16, and 15, respectively) both were statistically significantly less than controls. In a follow-up study, mated dams treated with ADN at the same doses and examined at gestation days (GDs) 10 and 20 showed an effect in fetus loss similar to that seen in the reproductive screen. A pre- versus postimplantation dosing regimen indicated that implantation is vulnerable to ADN effects during the preimplantation period (GDs 1-3). No implantation sites were found in the rats treated with 2000 mg ADN/L drinking water (target dose of 160 mg ADN/kg/day) during GDs 1-3. Numbers of implantation sites found in the rats treated during GDs 4-8 were similar to those found in the control group. The pituitary was not identified specifically in this study as the site of primary action, but serum progesterone was reduced by 27%, which may have resulted in reduced fertility.
Reduction of Selenite and Detoxification of Elemental Selenium by the Phototrophic Bacterium <i>Rhodospirillum rubrum</i> (1999)

The effect of selenite on growth kinetics, the ability of cultures to reduce selenite, and the mechanism of detoxification of selenium were investigated by using Rhodospirillum rubrum. Anoxic photosynthetic cultures were able to completely reduce as much as 1. 5 mM selenite, whereas in aerobic cultures a 0.5 mM selenite concentration was only reduced to about 0.375 mM. The presence of selenite in the culture medium strongly affected cell division. In the presence of a selenite concentration of 1.5 mM cultures reached final cell densities that were only about 15% of the control final cell density. The cell density remained nearly constant during the stationary phase for all of the selenite concentrations tested, showing that the cells were not severely damaged by the presence of selenite or elemental selenium. Particles containing elemental selenium were observed in the cytoplasm, which led to an increase in the buoyant density of the cells. Interestingly, the change in the buoyant density was reversed after selenite reduction was complete; the buoyant density of the cells returned to the buoyant density of the control cells. This demonstrated that R. rubrum expels elemental selenium across the plasma membrane and the cell wall. Accordingly, electron-dense particles were more numerous in the cells during the reduction phase than after the reduction phase.
Gallium-arsenide electro-optic modulators. (1966)

Electro-optic modulators for IR region 0.9 to 16 microns constructed by using large single crystals of high resistivity gallium arsenide
Development of Diagnosis System for Hub Bearing Fault in Driving Vehicle (2011)

In this paper, we propose effective diagnosis algorithm for hub bearing fault in driving vehicle using acceleration signal and wheel speed signal measured in hub bearing unit or knuckle. This algorithm consists of differential, envelope and power spectrum method. We developed diagnosis system for realizing proposed algorithm. This system consists of input device including acceleration sensor and wheel speed sensor, calculation device using Digital Signal Processor (DSP) and display device using Personal Digital Assistant (PDA). Using this diagnosis system, a driver can see hub bearing fault(flaking) from the vibration in driving vehicle. With early repairing, he can keep good ride feeling and prevent accident of vehicle resulting from hub bearing fault.
Evidence of exotoxin secretion of <i><scp>P</scp>iscirickettsia salmonis</i>, the causative agent of piscirickettsiosis (2013)

Piscirickettsia salmonis is the aetiological agent of piscirickettsiosis, a disease which affects a variety of teleost species and that is particularly severe in salmonid fish. Bacterial-free supernatants, obtained from cultures of three isolates of Piscirickettsia salmonis, were inoculated in Atlantic salmon, Salmo salar L., and in three continuous cell lines in an effort to determine the presence of secretion of extracellular products (ECPs) by this microorganism. Although steatosis was found in some liver samples, no mortalities or clinical signs occurred in the inoculated fish. Clear cytotoxicity was observed after inoculation in the cell lines CHSE-214 and ASK, derived from salmonid tissues, but not in MDBK, which is of mammalian origin. The degree of cytotoxicity of the ECPs was different among the P. salmonis isolates tested. The isolate that evidenced the highest cytotoxicity in its ECPs exhibited only an intermediate virulence level after challenging fish with bacterial suspensions of the three P. salmonis isolates. Almost complete inhibition of the cytotoxic activity of ECPs was seen after proteinase K treatment, indicating their peptidic nature, and a total preclusion of the cytotoxicity was shown after their incubation at 50 °C for 30 min. Results show that P. salmonis can produce ECPs and at least some of them are thermolabile exotoxins that probably play a role in the pathogenesis of piscirickettsiosis.
Checksum-based loss differentiation (2003)

In a wireless environment the common transport protocol assumption that all packet losses are due to congestion no longer holds true. If the transport protocols react identically to both congestion and non-congestion related losses, performance will degrade. To avoid this performance problem, transport protocols must be able to differentiate between losses that are due to congestion and losses that are due to wireless link errors. Suitable congestion avoidance behavior can then be applied as appropriate. This paper overviews previous work on loss differentiation, and proposes a checksum-based scheme. The proposed scheme reuses the checksums already available at various layers in the receiver end-host protocol stack. It is an end-to-end solution for the case where the lossy link is the last hop. Header decoding, data integrity and other issues related to the implementation of our checksum-based scheme are also discussed.
Options in Gas Turbine Power Augmentation Using Inlet Air Chilling (1990)

Gas Turbine Power Augmentation in a Cogeneration Plant using inlet air chilling is investigated. Options include absorption chillers, mechanical (electric driven) chillers, thermal energy storage. Motive energy for the chillers is steam from the gas turbine exhaust or electrical energy for mechanical chillers. Chilled water distribution in the inlet air system is described. Overall economics of the power augmentation benefits is investigated.
Ki67 Changes Identify Worse Outcomes in Residual Breast Cancer Tumors After Neoadjuvant Chemotherapy (2018)

This study evaluates the change in Ki67 percentage before and after neoadjuvant chemotherapy (NAC) and its relationship with survival outcomes in patients with breast cancer who did not achieve complete pathological response (pCR). These patients, a heterogeneous group with diverse prognoses that cannot be treated using a single algorithm, pose a challenge to clinicians. This study identified a subgroup of these patients with a poor prognosis, those with luminal B-like tumors without a Ki67 decrease after NAC, thus justifying the introduction of new therapeutic strategies for patients who already present a favorable prognosis (luminal B-like with Ki67 decrease).
Bone marrow mesenchymal stem cells induce division arrest anergy of activated T cells (2005)

It has been shown that mesenchymal stem cells (MSCs) induce T cells to become unresponsive. We characterized the phenotype of these T cells by dissecting the effect of MSCs on T-cell activation, proliferation, and effector function. For this purpose, an in vitro murine model was used in which T-cell responses were generated against the male HY minor histocompatibility antigen. In the presence of MSCs, the expression of early activation markers CD25 and CD69 was unaffected but interferon-gamma (IFN-gamma) production was reduced. The inhibitory effect of MSCs was directed mainly at the level of cell proliferation. Analysis of the cell cycle showed that T cells, stimulated in the presence of MSCs, were arrested at the G1 phase. At the molecular level, cyclin D2 expression was profoundly inhibited, whereas p27(kip1) was up-regulated. When MSCs were removed from the cultures and restimulated with the cognate peptide, T cells produced IFN-gamma but failed to proliferate. The addition of exogenous interleukin-2 (IL-2) did not restore proliferation. MSCs did not preferentially target any T-cell subset, and the inhibition was also extended to B cells. MSC-mediated inhibition induces an unresponsive T-cell profile that is fully consistent with that observed in division arrest anergy.
Museo d'Arte Contemporanea a Stoccarda (1991)

Bleeding is a rare but fatal complication after radiotherapy for nasoparyngeal carcinoma (NPC). In this article, we report an NPC case treated with radiotherapy complicated with bleeding of the common carotid artery(CCA). A 44-year-old man with NPC was treated with external radiotherapy 19 years ago, and a second course of treatment to the same field was administrated because of local nasoparyngeal recurrence 4 years ago. The patient was admitted to our hospital for massive bleeding. Conservative therapy including routine medication, blood transfusion and local compression showed almost no effect. Emergency carotid angiography revealed bleeding from the left CCA, and a self-expanding covered stent was deployed through percutaneous transluminal femoral approach. After the placement of the covered stent, angiography showed the bleeding was successfully controlled. So self-expanding covered stenting may be a safe, effective and minimal-invasive option for bleeding of the carotid artery. Long-term follow-up is required for further evaluation.
A new class of resonant antennas (1991)

A new class of wire antennas called meander antennas is introduced as possible elements for size reduction. Efficiency is affected only by the ohmic losses in the wire, and cross polarization is negligible. An increase in the number of meander sections introduces less size reduction in return for an improved bandwidth. These antennas can be used to reduce the size of existing wire antennas such as Yagi-Uda antennas and log-periodic dipole arrays. A size reduction in the resonant length typically from 25-40% is obtained. More size reduction is obtained by decreasing the radius of the wire or increasing the separation of the folded arms.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Exhaled Nitric Oxide Concentrations during Treatment of Wheezing Exacerbation in Infants and Young Children (1999)

While it is known that exhaled nitric oxide (ENO) is increased in adults and school children with asthma exacerbation probably as an expression of disease activity, no studies have investigated whether this phenomenon also occurs in infants and young children with recurrent wheeze exacerbation. We measured ENO in 13 young children (mean age 20.2 mo) with recurrent wheeze (Group 1) during an acute episode and after 5 d of oral prednisone therapy. ENO was measured also in nine healthy control subjects (Group 2) (mean age 16.9 mo) and in six children with a first-time viral wheezy episode (Group 3) (mean age 11 mo). To measure ENO, infants inhaled NO-free air via a face mask from a reservoir and, through a nonrebreathing valve, exhaled in a collecting bag that was analyzed by chemiluminescence. To address the question of whether the levels of ENO collected in the bag are a reflection of the pulmonary airway, ENO determinations were performed in two healthy infants before and after tracheal intubation for elective surgery. During the acute episode of wheezing the mean (+/- SEM) value of ENO in children with recurrent wheeze (Group 1) was 14.1 +/- 1.8 ppb, almost threefold higher than in healthy control subjects (5.6 +/- 0.5 ppb, p < 0.001). After steroid therapy we found a mean fall of 52% in ENO (5.9 +/- 0.7 ppb, p < 0.01) compared with baseline values. ENO values measured before and after intubation in two infants were 6 ppb and 5 ppb in one child and 7 ppb and 6 ppb in the other one. The mean value of ENO of children with first-time wheeze (Group 3) was 8.3 +/- 1.3 ppb, significantly lower (p < 0.05) than the value of children with recurrent wheeze (Group 1). In conclusion, we describe a method to measure ENO in young children and show that infants with recurrent wheeze have elevated levels of ENO during exacerbation that rapidly decrease after steroid therapy. This suggests that, in these children, airway inflammation could be present at a very early stage.
تعزيز إتقان الصفات الفوق المقطعية عند متعلمي اللغة الإنجليزية كلغة أجنبية عن طريق الأغاني الإنجليزي (2022)

تهدف الدراسة الحالية الى الاستخدام التداولي و الادائي للأغاني الإنجليزية في تدريس الصفات الفوق المقطعية لللغة الإنجليزية لطلاب اللغة الإنجليزية كلغة أجنبية. في الواقع ، نمط النبري لللغة الإنجليزية غالبًا ما يعسر مهمة تدريس الصفات الفوق المقطعية. من بين التقنيات التي قد يلجأ إليها مدرس اللغة الإنجليزية كلغة أجنبية من أجل تخطي هذه الصعوبة هي استخدام الأغاني الإنجليزية أثناء تدريس الصفات الفوق المقطعية. و من أجل تبيان الفكرة السالفة الذكر، تم إجراء اختبارين لـ 30 طالب ليسانس تخصص الغة الإنجليزية وذلك بجامعة مستغانم. حيث يتضمن الاختبار الأول إنتاج جمل عادية للتحقق من تطبيق النير في الجملة. بينما يتضمن الاختبار الثاني الاستماع إلى أغنية إنجليزية وإعادة إصدار بعض مقاطعها. كما تشير نتائج الدراسة إلى أن استخدام الأغاني الإنجليزية يساعد متعلمي اللغة الإنجليزية كلغة أجنبية على تعزيز إتقانهم للصفات الفوق المقطعية للغة الإنجليزية لأن الإيقاع الموسيقي للأغاني يساعد المتعلمين في تعيين ثم إتقان الصفات الفوق المقطعية
A Structural Hypothesis for the Transition between Bent and Extended Conformations of the Leukocyte β2 Integrins (2007)

Integrins mediate cell adhesion in response to activation signals that trigger conformational changes within their ectodomain. It is thought that a compact bent conformation of the molecule represents its physiological low affinity state and extended conformations its active state. We have determined the structure of two integrin fragments of the beta2 subunit. The first structure, consisting of the plexin-semaphorin-integrin domain, hybrid, integrin-epidermal growth factor 1 (I-EGF1), and I-EGF2 domains (PHE2), showed an L-shaped conformation with the bend located between the I-EGF1 and I-EGF2 domains. The second structure, which includes, in addition, the I-EGF3 domain, showed an extended conformation. The major reorientation of I-EGF2 with respect to the other domains in the two structures is accompanied by a change of torsion angle of the disulfide bond between Cys(461)-Cys(492) by 180 degrees and the conversion of a short alpha-helix (residues Ser(468)-Cys(475)) into a flexible coil. Based on the PHE2 structure, we introduced a disulfide bond between the plexin-semaphorin-integrin domain and I-EGF2 domains in the beta2 subunit. The resultant alphaLbeta2 integrin (leukocyte function-associated antigen-1) variant was locked in a bent state and could not be detected with the monoclonal antibody KIM127 in Mg(2+)/EGTA. However, it retained the binding activity to ICAM-1. These results provide a structural hypothesis for our understanding of the transition between the resting and active states of leukocyte function-associated antigen-1.
Arterial pressure measurement: Is the envelope curve of the oscillometric method influenced by arterial stiffness? (2007)

Measurement of peripheral arterial pressure using the oscillometric method is commonly used by professionals as well as by patients in their homes. This non invasive automatic method is fast, efficient and the required equipment is affordable with a low cost. The measurement method consists of obtaining parameters from a calibrated decreasing curve that is modulated by heart beats witch appear when arterial pressure reaches the cuff pressure. Diastolic, mean and systolic pressures are obtained calculating particular instants from the heart beats envelope curve. In this article we analyze the envelope of this amplified curve to find out if its morphology is related to arterial stiffness in patients. We found, in 33 volunteers, that the envelope waveform width correlates to systolic pressure (r=0.4, p<0.05), to pulse pressure (r=0.6, p<0.05) and to pulse pressure normalized to systolic pressure (r=0.6, p<0.05). We believe that the morphology of the heart beats envelope curve obtained with the oscillometric method for peripheral pressure measurement depends on arterial stiffness and can be used to enhance pressure measurements.
La révolution multiculturelle (2000)

La guerre est vraisemblablement apparue très tôt dans la vie sociale, avant la dernière glaciation sans doute, même si nous ne pouvons le prouver. Déjà devenue endémique dans certaines régions il y a 15 000 ans approximativement, elle va bouleverser l’économie en y ajoutant les effets de la prédation interhumaine. Les prémices de l’agriculture sont perceptibles dès avant la dernière glaciation, et toutes les composantes de la vie paysanne ont été expérimentées des milliers d’années avant le passage à l’agriculture et à l’élevage. L’économie de guerre s’amplifiant encore après l’arrivée du paysan, ce seront les guerriers qui inventeront l’État.
REVIEWS (1961)

Journal Article REVIEWS Get access Saint Peter and the Popes. By MICHAEL WINTER. Pp. vi+236. Baltimore: Helicon Press; London: Darton, Longman & Todd, 1960. 25S. H. BENEDICT GREEN H. BENEDICT GREEN Search for other works by this author on: Oxford Academic Google Scholar The Journal of Theological Studies, Volume XII, Issue 2, October 1961, Pages 355–356, https://doi.org/10.1093/jts/XII.2.355 Published: 01 October 1961
Relationships between IGF-I and Weight Z Score, BMI, Tricipital Skin-Fold Thickness, Type of Feeding in Healthy Infants in the First 5 Months of Life (2005)

These results show that the IGF-I serum concentration is higher in FF infants. The observed association between IGF-I and Z score for weight, BMI, tricipital skin-fold thickness confirms the effect of different infant feeding on body size.
Comparison of Oven-drying Methods for Determination of Moisture Content in Feed Ingredients (2014)

An accurate assessment of moisture content in feed ingredients is important because moisture influences the nutritional evaluation of feedstuffs. The objective of this study was to evaluate various methods for moisture content determination. In Exp. 1, the weight loss on drying (LOD) of corn, soybean meal (SBM), distillers dried grains with solubles (DDGS), whey permeate, whey powder, spray-dried porcine plasma (SDPP), fish meal, and a mixed diet of these 7 ingredients were measured by oven drying at 135°C for 2 h. Additionally, the samples were dried at 105°C for 3, 6, 9, 12, or 15 h. The LOD contents of the DDGS, whey permeate, and whey powder measured by drying at 135°C for 2 h were greater than the values measured by drying at 105°C for 3 h (p<0.05). All samples except SDPP (p = 0.70) dried at 105°C for 6, 9, 12, or 15 h caused more LOD compared with the samples dried for at 105°C for 3 h (p<0.05). The LOD contents of the individual ingredients were additive when dried at 105°C regardless of drying time. In Exp. 2, moisture contents of corn, SBM, wheat, whey permeate, whey powder, lactose, and 2 sources of DDGS (DDGS1 and DDGS2) were measured by the Karl Fischer method, oven drying at 135°C for 2 h, and oven drying at 125°C, 115°C, 105°C, or 95°C for increasing drying time from 1 to 24 h. Drying samples at 135°C for 2 h resulted in higher moisture content in whey permeate (7.5% vs 3.0%), whey powder (7.7% vs 3.8%), DDGS1 (11.4% vs 7.5%), and DDGS2 (13.1% vs 8.8%) compared with the Karl Fischer method (p<0.05). Whey permeate and whey powder were considerably darkened as the drying time increased. In conclusion, drying samples at 135°C for 2 h is not appropriate for determining the moisture content in whey permeate, whey powder, or DDGS as well as the mixed diet containing these ingredients. The oven-drying method at 105°C for 5 to 6 h appears to be appropriate for whey permeate and whey powder, and at 105°C for 2 to 3 h for DDGS.
The lipid-linked oligosaccharide donor specificities of Trypanosoma brucei oligosaccharyltransferases (2012)

We recently presented a model for site-specific protein N-glycosylation in Trypanosoma brucei whereby the TbSTT3A oligosaccharyltransferase (OST) first selectively transfers biantennary Man(5)GlcNAc(2) from the lipid-linked oligosaccharide (LLO) donor Man(5)GlcNAc(2)-PP-Dol to N-glycosylation sequons in acidic to neutral peptide sequences and TbSTT3B selectively transfers triantennary Man(9)GlcNAc(2) to any remaining sequons. In this paper, we investigate the specificities of the two OSTs for their preferred LLO donors by glycotyping the variant surface glycoprotein (VSG) synthesized by bloodstream-form T. brucei TbALG12 null mutants. The TbALG12 gene encodes the α1-6-mannosyltransferase that converts Man(7)GlcNAc(2)-PP-Dol to Man(8)GlcNAc(2)-PP-Dol. The VSG synthesized by the TbALG12 null mutant in the presence and the absence of α-mannosidase inhibitors was characterized by electrospray mass spectrometry both intact and as pronase glycopetides. The results show that TbSTT3A is able to transfer Man(7)GlcNAc(2) as well as Man(5)GlcNAc(2) to its preferred acidic glycosylation site at Asn263 and that, in the absence of Man(9)GlcNAc(2)-PP-Dol, TbSTT3B transfers both Man(7)GlcNAc(2) and Man(5)GlcNAc(2) to the remaining site at Asn428, albeit with low efficiency. These data suggest that the preferences of TbSTT3A and TbSTT3B for their LLO donors are based on the c-branch of the Man(9)GlcNAc(2) oligosaccharide, such that the presence of the c-branch prevents recognition and/or transfer by TbSTT3A, whereas the presence of the c-branch enhances recognition and/or transfer by TbSTT3B.
Traumatic brachiocephalic artery pseudoaneurysm following penetrating injury on the contralateral side (2012)

Introduction: Trauma to the brachiocephalic artery is uncommon, but is associated with significant morbidity and mortality. The development of pseudoaneurysm following both penetrating and blunt trauma have been well documented, mostly in the setting of blunt trauma. Case Report: A highly unusual case of a patient who developed a pseudoaneurysm of the brachiocephalic artery on the side contralateral to the side of the original penetrating injury has been reported. Conclusion: Pseudoaneurysm of the brachiocephalic artery following penetrating neck injury in the contralateral side is exceeding rare. It may remain symptomatic and present long after the initial injury. Clinician must have a high index of suspicion for such potentially serious injury.