gebhart/patrepeval huggingface dataset:
Low-voltage low-power controllable preamplifier for electret microphones (1993)

A low-voltage low-power analog controllable preamplifier for electret microphones is discussed. It has been designed for a single supply voltage of 1.0 V, whereas its average power consumption amounts to some tens of microwatts. A DC current controls its gain directly into decibels. The design meets specifications concerning accuracy, bandwidth, and noise properties suitable for most applications in portable telephone equipment, portable transceivers, and hearing aids. Much attention has been paid to the dynamic range of the input signal, noise, and offset properties. The circuit has been realized in a semicustom IC process. Simulation and measurement data of the most important properties are presented.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Clinically relevant positive controls validate the use of serial FACS analysis, and video endoscopy in two murine adoptive transfer models of colitis (HUM1P.315) (2015)

Abstract The adoptive transfer of naïve TH cells into immunodeficient mice is one of the best characterized immunological models of chronic colitis (CC). Traditional disease severity endpoints of weight loss and histopathology are often misleading since colitis may occur in the absence of weight loss, mice may not engraft, and weight loss and colitis may respond independently to established or experimental treatment. To overcome these limitations, we analyzed peripheral blood to track engraftment, and performed serial endoscopies to assess onset and severity of CC in two murine models of adoptive transfer-induced colitis: naive T cells from C57Bl/6J males sorted as either CD4+, CD45RBHIGH (FACS), or CD4+, CD44-, CD62L+ (negative magnetic separation) were injected IP into RAG2-/- males. Onset of colitis corresponded with the onset of weight loss, and day 14 peripheral blood CD4+ counts correlated well with both final weight loss (R2=0.74) and final endoscopy score (R2=0.79), indicating that day 14 CD4+ count was a reliable predictor of disease severity. Treatment with anti-TNFα had little effect on terminal weight loss, but significantly affected endoscopy score (2.0±0.15 vs. 1.1±0.14 at day 49 on a scale of 0-3). Together these observations suggest that endoscopy is a useful addition to weight change as a complete readout for assessing in-life disease severity in these models.
DNA binding activity of NtrC from <i>Rhizobium</i> grown on different nitrogen sources (1994)

The DNA‐binding activity of the NtrC protein can be demonstrated in gel retardation assays with concentrated protein extracts of Rhizobium etli . Using extracts from either the wild type or a ntrC mutant strain and an antiserum raised against the NtrC protein, we demonstrate specific binding of NtrC to the upstream regulatory region of the glnII gene, where two putative NtrC‐binding sites are present. KNO 3 ‐grown bacteria contain less NtrC protein and more NtrC‐binding activity than NH 4 Cl‐grown bacteria, thus showing that with this protocol it is possible to detect changes in NtrC‐binding activity. The advantages of this assay system in comparison with that using pure proteins is discussed.
A new photo-Fries rearrangement of methyl aryl oxalates (1972)

T. Inoue, Y. Shigemitsu and Y. Odaira, J. Chem. Soc., Chem. Commun., 1972, 668 DOI: 10.1039/C39720000668
NAND Circuits (1999)

Abstract The sections in this article are Digital Logic Background NAND Circuit Technologies NAND Characteristics Applications Current Research in Logic Circuits Conclusions
From Molecular Shape to Potent Bioactive Agents I: Bioisosteric Replacement of Molecular Fragments (2008)

Ligand-based virtual screening: By means of shape- and pharmacophore-based virtual screening, a potent PPARα-selective activator was identified from a large compound collection with minimal experimental effort. This compound represents a scaffold-hop from known PPAR agonists and provides proof-of-concept for a novel ligand-based virtual screening approach. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
The 66 kDa component of yeast SF1, stimulatory factor I, is hsp6O (1992)

DNA polymerase epsilon stimulatory factor I (SFI) has been shown to contain three peptides, p66, p37 and p13. Two of these components have been identified. The p66 gene was cloned by using a p66 antibody to screen a lambda gt11 library. A portion of the gene was sequenced and confirmed to encode p66 by the presence of protein sequence corresponding to that of p66 tryptic peptides. The gene was identified as HSP60 by a homology search of GenBank. Tryptic peptides of p37 were sequenced and identified as belonging to yeast translation initiation factor 4A by a homology search of PIR. The HSP60 gene maps to chromosome XII.
Feline urethral plugs. Etiology and pathophysiology. (1996)

Feline urethral plugs commonly are composed of large quantities of matrix mixed with minerals (especially struvite). However, some urethral plugs are composed primarily of matrix, some consist of sloughed tissue, blood, and/or inflammatory reactants, and a few are composed primarily of aggregates of crystalline minerals. The formation of matrix-crystalline urethral plugs may be analogous to the preparation of fruit jello.
Big Data Analytics and Network Calculus Enabling Intelligent Management of Autonomous Vehicles in a Smart City (2018)

Artificial intelligence (AI) and big data analytics enable autonomous vehicles (AVs) to dramatically change future intelligent transportation in smart cities. AVs are envisaged to evolve to a service rather than a product in the future. To provide best user experience of such services, three primary factors, namely, waiting time, travel time, and supply of AV services, are taken into consideration in a multiobjective optimization. Conventional optimization of services relies on traffic flow analysis over a queuing network model. However, due to the mobility of vehicles and the transfer uncertainty of road networks, the queuing network analysis is too complicated and practically intractable. For accuracy and convenient processing, network calculus (NC) is extended to model the queueing problem in this paper. The optimal number of available AVs can be identified by guaranteeing the waiting time of customers. The satisfaction of AV services can be viewed as a supply and demand problem, and optimized by bipartite graph matching. In order to reduce the average travel time, especially for rush hours with heavy traffic, we further propose a new online AVs fleet management scheme with congestion control for smart cities. It is shown that the intelligent management of AV fleet can be efficiently achieved, outperforming the cases of traditional vehicles. NC-assisted AI enables an efficient intelligent transportation paradigm in smart cities, while achieving substantial energy saving.
Molecular controlled semiconductor devices (2008)

Two-dimensional arrangements of molecules can show remarkable cooperative electronic effects. Such effects can serve to couple molecular properties with semiconductor devices and to achieve direct electronic sensing of chemical and physical processes via electrostatic effects, i.e., without transfer of charge or matter between the locus of sensing and that of detection.
Influence of human tryptophan hydroxylase 2 N‐ and C‐terminus on enzymatic activity and oligomerization (2007)

Tryptophan hydroxylase (TPH) catalyses the first and rate limiting step in the biosynthesis of the neurotransmitter serotonin. There are two TPH isoenzymes in humans, encoded by two different genes: TPH1 and the recently described TPH2. We have expressed both human enzymes and various deletion mutants of TPH2 (DeltaN44, DeltaC17, DeltaC19, DeltaC51) in COS7 cells. TPH1 and 2 displayed different kinetic properties with a lower K(m) value of TPH1. Removal of 44 amino acids from the N-terminus of TPH2 resulted in a 3-4-fold increased V(max), which indicates a strong inhibitory function of this part on the enzymes activity. TPH1 and 2 were able to form homooligomers and also heterooligomers with each other. The different deletion mutants (DeltaC17, DeltaC19 and DeltaC51), which lack the putative C-terminal leucine zipper tetramerization domain, existed as monomeric enzymes. While short deletions (DeltaC17 and DeltaC19) hardly changed V(max) values, the DeltaC51 mutant lost 99% of TPH activity. These data identify a region between the C-terminal oligomerization domain and the catalytic domain, which is indispensable for TPH2 activity.
Colchicine myopathy in a patient with familial Mediterranean fever and normal renal function (2003)

Introduction Patients with familial Mediterranean fever (FMF) routinely take large daily doses of colchicine to both prevent and abort acute attacks (1,2) and to reduce the risk of developing amyloidosis (3). Unfortunately, colchicine can also cause a number of toxic side effects, including neuromyopathy. Almost all cases of colchicine neuromyopathy previously described have been associated with renal insufficiency (4). We report the first case of biopsy-confirmed myopathy due to chronic colchicine administration in an adult with FMF and normal renal function.
Comparison of O-(2-18F-fluoroethyl)-L-tyrosine PET and 3-123I-iodo-alpha-methyl-L-tyrosine SPECT in brain tumors. (2004)

The significant correlation of the TBRs of (18)F-FET and (123)I-IMT indicates that clinical experiences of brain tumor diagnostics with (123)I-IMT SPECT might be valid for (18)F-FET PET although substantial differences of the physiologic behavior were identified in extracerebral tissue. As (18)F-FET PET allows improved discrimination of anatomic structures and the tumor-to-brain contrast was significantly superior compared with (123)I-IMT SPECT scans, the results are encouraging for further evaluation of (18)F-FET for imaging brain tumors.
Rapid computation of Fourier texture descriptors (1977)

Computer vision systems based on general purpose computers often need efficient texture description algorithms. One common method is to calculate two-dimensional discrete Fourier transforms over windowed regions of the light intensity matrix. Although these methods described in the literature are based on the fast Fourier transform algorithm, the computation time is still too high to permit the description of texture for as many windows as are needed for good segmentation. When a set of transforms over a window at every position of the matrix is needed, an efficient method can be used. It saves information computed for previous windows and uses it to reduce the effort expended on the current window. For a window N x N and an image matrix M x M, the time complexity is reduced from 0(N2M2logN) to 0(N2M2). This complexity cannot be beaten by any nonparallel algorithm. I.
0462 Use of a Transformed ECG signal to Detect Respiratory Effort During Apnea (2019)

Apneas can be incorrectly classified as central using respiratory inductance plethysmography (RIP) effort belts. Use of chest wall EMG to detect respiratory effort (inspiratory EMG bursts) during apnea can provide complementary information about effort and improve apnea classification. However, not all sleep centers use chest wall EMG and the signal does not always exhibit inspiratory bursts. The purpose of this study was to evaluate the ability of a transformed electrocardiographic signal (TECG) recorded using standard ECG electrode placement to detect inspiratory bursts from the underlying surface chest wall electromyographic (EMG) activity and the utility of the transformed signal for apnea classification compared to uncalibrated RIP belts. Part 1: 250 consecutive adult studies without regard to respiratory events were retrospectively reviewed. The ECG signal was transformed with high pass filtering and viewed with increased sensitivity and channel clipping (TECG-FC) to determine the fraction of studies with inspiratory burst visualization as compared to chest wall EMG (right thorax). Part 2: 445 consecutive studies were reviewed to select 40 with ≥ 10 obstructive and ≥ 10 mixed or central apneas (clinical scoring). Five obstructive and 5 central or mixed apneas were randomly selected from each study. A blinded scorer classified the apneas using either RIP or a transformed ECG signal (TECG-FB) using high pass filtering and QRS blanking. The agreement between the two classifications was determined by kappa analysis. Part 1: Inspiratory burst visualization was noted in the TECG-FC and chest wall EMG signals in 83% and 71% of the studies (P < 0.05). Part 2: The percentage agreement between RIP and TECG-FB classification was 89.5%, the kappa statistic was 0.83 (95% CI 0.79 to 0.87) and interclass correlation was 0.83 showing good agreement. Using RIP bands 116 apneas were classified as central. Of these 18 (15.5%) were classified as obstructive or mixed by the transformed ECG signals. A transformed ECG signal can exhibit inspiratory bursts in a high proportion of patients and is potentially useful for detecting respiratory effort and apnea classification. None
Modèle et simulations numériques de la proparation acoustique non-linéaire dans les conduits (1997)

cote interne IRCAM: Msallam97a
Thermal and metabolic responses of coastal Eskimos during a cold night (1962)

Metabolic and thermal studies were conducted at night at Pangnirtung, N.W.T., on a group of ten Eskimo hunters from Cumberland Sound, Baffin Island, and on three white controls, to compare their reactions to cold (5 ± 1 C) with that of other racial groups. Cumberland Sound Eskimos maintained a resting metabolism that was elevated, according to DuBois standards, during sleep on warm nights. This elevation was not found in hospitalized men who had been living for an average of 6 months in Edmonton, Alberta. During exposure to moderate cold, the Cumberland Sound Eskimos and white controls had an elevated metabolism, shivering, and a disturbed sleep. Peripheral temperatures were maintained at a higher level in Eskimos than in whites. Because of the absence of marked physiological differences between Eskimos and whites, it is concluded that the principal adaptation of these Eskimos to their climate is technological. Submitted on June 4, 1962
Stabilisation of BCG vaccines. (1996)

Aquired resistance against tuberculosis depends on the survival, multiplication and persistence of BCG in the host organs. Therefore, the viability and stabilisation during storage of BCG vaccine constitute a major attribute for good immunogenicity. Different factors which influence BCG viability have been studied. Among the more important ones it was found that a very large number of viable bacilli are killed when vaccine is manufactured in the conventional way by ball milling the surface-grown bacillary mass. The dispersed deep-grow BCG offers the advantage that all bacilli are live in the fresh suspension before stabilisation procedures are applied. Two procedures of stabilisation have been used, freezing and freeze-drying. Preservation by resuspending BCG in different cryoprotective solutions has been followed by storage at low temperatures. Complete survival is obtained when this vaccine was frozen in glycerol solutions and stored for many years at -70 degrees C. Freeze-drying killed more than 50% of the live bacilli in the fresh suspension; the remaining freeze-dried live bacilli were preserved at -30 degrees C for 20 years or at 4 degrees C for at least one year. They also resist exposure to 37 degrees C for one month. Nevertheless, most of the BCG bacilli in freeze-dried vaccines are dead. In conclusion the best BCG viability is obtained with young dispersed-grown bacilli by both freezing and freeze-drying. Freezing is a good method of stabilisation for research purposes or cancer immunotherapy, and freeze-drying for BCG vaccination campaings in tuberculosis prevention. However, BCG stabilisation still needs improvement.
Light rays and waves on geodesic lenses (2018)

Starting from well-known absolute instruments for perfect imaging, we introduce a type of rotational-symmetrical compact closed manifolds, namely geodesic lenses. We demonstrate that light rays confined on geodesic lenses are closed trajectories. While for optical waves, the spectrum of geodesic lens is (at least approximately) degenerate and equidistant with numerical methods. Based on this property, we show a periodical evolution of optical waves and quantum waves on geodesic lenses. Moreover, we fabricate two geodesic lenses in sub-micrometer scale, where curved light rays are observed with high accurate precision. Our results may offer a new platform to investigate light propagation on curved surfaces.
Discrete sliding mode control with fuzzy adaptive reaching law on 6-PRRS parallel robot (2006)

Applying distributed control strategy, a discrete sliding mode controller (DSMC) with fuzzy adaptive reaching law is proposed to tracking the trajectory of 6-PRRS parallel robot. The detailed design procedure of the DSMC system with fuzzy adaptive reaching law is presented. The disturbances prediction, which guarantees the stability of the control system, is developed In order to attenuate the chattering phenomena, reaching law is actively tuned according fuzzy rule. Simulation study has been carried out to evaluate the performance of the proposed controller, and the results showed that the proposed controller has achieved a performance with minimum reaching time and smooth control actions. In addition, the results have also proven the effectiveness and robustness of the trajectory tracking of parallel robot characterized under disturbances and parameter uncertainties
Electromagnetic Environmental Effects Compendium (1993)

This report summarizes the electromagnetic environmental effects (E3) program of the U.S. Army Communications-Electronics Command (CECOM). The report includes background information on CECOM's role in the Army E3 program, presents the approach used to identify the electromagnetic environment, summarizes E3 criteria (i.e., the CECOM model electromagnetic environment), and provides a sample E3 assessment. The report also discusses electromagnetic trends and their implications. Electromagnetic Environment Effects(E3), Electromagnetic Environment(EME), Electromagnetic Interference(EMI), Electromagnetic Compatability (EMC), Electromagnetic criteria/techniques.
RNase H overproduction allows the expression of stress-induced genes in the absence of topoisomerase I (2003)

Induction of stress proteins in response to heat shock was found to be reduced significantly in Escherichia coli with DeltatopA mutation. RNase H overexpression in the DeltatopA mutant partially restored the sigma(32)-dependent induction of stress genes in response to high temperature and ethanol. The presence of overexpressed RNase H also improved the survival rate of the DeltatopA mutant after high temperature and oxidative challenges. Topoisomerase I is likely required during stress response for preventing accumulation of transcription-driven hypernegative supercoiling and R-loop formation at induced stress genes loci.
Heterogeneity, Segmental and Hydrogen Bond Dynamics, and Aging of Supramolecular Self-Healing Rubber (2013)

In recent years, self-healing materials have attracted increasing attention due to their potentially spontaneous self-repairing ability after mechanical damage. Here, we focus on a supramolecular self-healing rubber based on fatty acids following the work of Leibler and co-workers. We study the heterogeneous network structure and hydrogen bond dynamics as well as its significant aging properties using several experimental techniques. NMR experiments reveal that the rubber is basically a two-component system, with a ∼85% fraction of material rich in hydrogen-bonded structures and associated aliphatic moieties, undergoing a glass transition just below ambient temperature, and the other one being comprised of more mobile aliphatic chains. Changes in the IR bands corresponding to the NH bending and CO stretching vibrations show that water in the rubber not only takes the role of a plasticizer, reducing the glass transition temperature of the main component, but also is involved in changes of the hydrogen-bonding network. On the basis of shear rheology experiments and proton low-field NMR, we deduce that the rubber undergoes irreversible chemical cross-linking reactions at temperatures above 110 °C, going along with a weakening of its self-healing ability.
Optimum Combining in Dual-Hop AF Relaying for Maximum Spectral Efficiency in the Presence of Co-Channel Interference (2015)

The performance of optimum combining (OC) in amplify-and-forward (AF) relaying systems in the presence of co-channel interference (CCI) is analyzed using a tight approximation for the signal-to-interference-plus-noise ratio (SINR) at the destination. Two types of relaying protocols are studied, all-relay transmission with OC and best-relay transmission with OC. When CCI is present only at the destination, both relaying protocols achieve diversity gains up to M when interferer powers are scaled with the source and the relay powers, where M is the number of relays. Best-relay transmission with OC maximizes the spectral efficiency as each communication consumes only two time slots.
Uptake of Individual Amino Acids by the Human Brain (1973)

SummaryIndividual plasma amino acids were determined in simultaneously drawn arterial and jugular venous blood samples obtained from healthy postabsorptive subjects. Consistently positive A-V differences were observed for virtually all amino acids, indicating a net uptake of essential and nonessential amino acids by the brain in intact man.The authors are grateful to Chester Meyers for skillful technical assistance.
Uplink capacity of MIMO cellular systems with multicell processing (2008)

Multiple antennas are known to increase the link throughput by providing a multiplexing gain which scales with the number of antennas. Especially in cellular systems, multiple antennas can be exploited to achieve higher rates without the need for additional base station (BS) sites. In this direction, this paper investigates the multi-antenna capacity scaling in a cellular system which employs multicell processing (hyper-receiver). The model under investigation is a MIMO Gaussian cellular multiple-access channel (GCMAC) over a planar cellular array in the presence of power-law path loss and flat fading. Furthermore, the considered cellular model overcomes the assumption of user collocation utilized by previous models by incorporating uniformly distributed user terminals (UTs). The asymptotic eigenvalue distribution (a.e.d.) of the covariance channel matrix is calculated based on free-probabilistic arguments. In this context, we evaluate the effect of multiple BS/UT antennas on the optimal sum-rate capacity by considering a variable-density cellular system. Finally, the analytical results are interpreted in the context of a typical real-world macrocellular scenario.
Photolysis of isoeugenol (1977)

Photolysis of isoeugenol leads to E-Z isomerization, solvent addition, and the formation of dehydro-dimers.
On the Mortality Arising from Abdominal Hernia: With Suggestions for its Diminution (1868)

tality in support of some favourite sanitary measure, or in opposition to some dreaded reform, by those who may not yet have proved the falla- cies of sanitary statistics, or who do not perceive how small may be the bearing of any particular act or neglect upon the variations of a, general death-rate; or, again, who forget that the same figures in different places, and in populations differing as to age, class, and occupation, may represent totally different standards of health, vigour, and longevity.