gebhart/patrepeval huggingface dataset:
Interpretation of Gravity Data using 3D Euler Deconvolution, Tilt Angle, Horizontal Tilt Angle and Source Edge Approximation of the North-West Himalaya (2016)

The collision of the Indian plate and the Eurasian plate created shortening and imbrications with thrusting and faulting which influences northward tectonic movement. This plate movement has divided the Himalaya into four parts, viz. Outer Himalaya, Lesser Himalaya, Greater Himalaya, and Tethys Himalaya. The crystalline basement rock plays an imperative role for structural and tectonic association. The study has been carried out near Rishikesh-Badrinath neighborhood in the northwestern part of the Himalayan girdle with multifarious tectonic set up with thrusted and faulted geological setting. In this study area, 3D Euler deconvolution, horizontal gradient analysis, tilt angle (TILT) and horizontal tilt angle (TDX) analysis have been carried out using gravity data to delineate the subsurface geology and heterogeneity in the northwestern part of Himalaya. The Euler depth solutions suggest the source depth of about 12 km and various derivative analyses suggest the trend of the delineation thrust-fault boundaries along with the dip and strike direction in the study area.
Children's Voices: A Review of the Literature Pertinent to Looked‐After Children's Views of Mental Health Services (2007)

Service-user involvement is an essential component of mental health service provision. This review aims to synthesise literature that has attempted to elicit children's experiences of mental health services with particular reference to looked-after children. The review is limited to qualitative research with study inclusion based on a synthesis of good quality criteria. Identification of gaps in the literature, directions for further research and implications for service developments are discussed.
Binding of the Thyroid Hormone Receptor to a Negative Element in the Basal Growth Hormone Promoter Is Associated with Histone Acetylation (2003)

Nuclear thyroid hormone receptors (TRs) act as ligand-dependent activators, but paradoxically unliganded TRs can increase transcription of promoters containing negative response elements (nTRE), and hormone binding represses this activation. The rat growth hormone (GH) promoter contains a positive TRE and a nTRE. Ligand-dependent negative regulation mediated by the nTRE could play an important physiological role in restricting GH gene expression in non-pituitary cells that express TRs. With chromatin immunoprecipitation assays, we show here that the nTRE is responsible for binding of TR to the promoter in non-pituitary HeLa cells and that this element also governs transactivation by the unoccupied receptor and repression by triiodothyronine. Occupancy of the promoter by TR is concomitant with appearance of acetylated histone H3, and triiodothyronine causes release of the receptor as well as disappearance of the acetylated histone from the promoter. Although the nTRE overlaps the TATA box, the receptor does not exclude binding of TATA-binding protein, but could rather facilitate formation of the preinitiation complex. Furthermore, the proximal GH promoter is synergistically stimulated by unliganded TR and TATA-binding protein, whereas the ligand represses this cooperation. Constitutive receptor activity and synergism with TATA-binding protein require binding of corepressors. Furthermore, inhibitors of histone deacetylases enhance promoter activation by the unliganded receptor and reduce triiodothyronine-dependent repression, whereas expression of HDAC1 reverses promoter stimulation. This suggests that partitioning of histone acetylases and deacetylases between the receptors and basal transcription factors could be involved in regulation of the basal GH promoter by TRs.
α-Synuclein in Cerebrospinal Fluid of Alzheimer's Disease and Mild Cognitive Impairment (2013)

In addition to amyloid-β (Aβ) and tau, α-synuclein, best known for its role in Parkinson's disease (PD), has been suggested to be involved in cognition and pathogenesis of Alzheimer's disease (AD). We investigate the potential of α-synuclein in cerebrospinal fluid (CSF) as a biomarker of cognitive decline in AD, and its prodromal phase, mild cognitive impairment (MCI). Using an established, sensitive Luminex assay, we measured α-synuclein levels in the CSF of a cohort of close to 400 healthy control, MCI, and AD subjects obtained from the Alzheimer's Disease Neuroimaging Initiative (ADNI) and factored in APOE genotype in data analysis. CSF α-synuclein levels were significantly higher in the MCI (p = 0.005) and AD (p < 0.001) groups, compared to controls. However, receiver operating characteristic (ROC) curve analysis suggests that CSF α-synuclein level on its own only offered modest sensitivity (65%) and specificity (74%) as a diagnostic marker of AD, with an area under the curve (AUC) value of 0.719 for AD versus controls. The effect of APOE genotype, if any, was quite subtle. However, there was a significant correlation between α-synuclein and cognition (p = 0.001), with increased α-synuclein levels associated with decreased Mini-Mental State Exam scores. Our results support a role for α-synuclein even in MCI, the early phase of AD, in addition to being a potential contributor in MCI and AD diagnosis or monitoring of disease progression.
Growth and juvenile development of Uca maracoani Latreille 1802-1803 in laboratory conditions (Crustacea, Decapoda, Brachyura, Ocypodidae). (2008)

The life cycle of decapod crustaceans can be classified into three distinct morphological phases: larval, juvenile and adult. Despite its recognized importance, studies of the juvenile phase have been neglected. The present Study aimed to analyze the growth of juveniles from a single population of Uca maracoani under laboratory conditions, and also to describe the morphological differentiation of pleopods in each sex. Megalopae and juvenile crabs or U. maracoani obtained on a Mud beach at Jabaquara, Paraty, on the southern coast of the state of Rio de Janeiro (Brazil), were reared in the laboratory. The specimens were checked daily for molts and deaths. The carapace widths (CW) of intact exuviae and dead individuals were measured under a stereoscopic microscope provided with a micrometer rule. These data allowed the definition of a growth equation as well as the stages related to the beginning of pleopod development, which begins when females reach 3.0 mill CW (6th juvenile developmental stage), similar to the sizes reported for other species of the genus. In males, however, pleopods appear when the crabs reach 3.5 mm CW, equivalent to the 7th developmental stage. This difference may be related to differential growth between sexes. It also may be a consequence of laboratory rearing, or may represent an actual feature of the species.
Treatment of Primary Pulmonary Aspergillosis: An Assessment of the Evidence (2016)

<i>Aspergillus</i> spp. are a group of filamentous molds that were first described due to a perceived similarity to an aspergillum, or liturgical device used to sprinkle holy water, when viewed under a microscope. Although commonly inhaled due to their ubiquitous nature within the environment, an invasive fungal infection (IFI) is a rare outcome that is often reserved for those patients who are immunocompromised. Given the potential for significant morbidity and mortality within this patient population from IFI due to <i>Aspergillus</i> spp., along with the rise in the use of therapies that confer immunosuppression, there is an increasing need for appropriate initial clinical suspicion leading to accurate diagnosis and effective treatment. Voriconazole remains the first line agent for therapy; however, the use of polyenes, novel triazole agents, or voriconazole in combination with an echinocandin may also be utilized. Consideration as to which particular agent and for what duration should be made in the individual context for each patient based upon underlying immunosuppression, comorbidities, and overall tolerance of therapy.
New Technology Architecture and Research Hotspot of Blockchain in 2020 (2020)

Blockchain technology is bringing new changes to the global financial landscape and immeasurable potential power for economic development in this new era. We believe that the development of blockchain technology has huge prospects, and it is necessary to sort out the current status of blockchain technology. Based on the synthesis of domestic and foreign research, this paper combines the development of blockchain in China in recent years, summarizes the current status of the architecture of blockchain technology, reviews its development and predicts its future development.
Treatment for agenesis of maxillary lateral incisors: a systematic review (2013)

There is no scientific evidence for any of the three most common types of treatment for agenesis of the maxillary lateral incisors. RCTs into this issue are still necessary.
Isolation of 4-hydroxy-2-(hydroxymethyl)-5-methyl-3(2H)furanone from sugar amino acid reaction mixtures (1987)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTIsolation of 4-hydroxy-2-(hydroxymethyl)-5-methyl-3(2H)furanone from sugar amino acid reaction mixturesJosef Hiebl, Franz Ledl, and Theodor SeverinCite this: J. Agric. Food Chem. 1987, 35, 6, 990–993Publication Date (Print):November 1, 1987Publication History Published online1 May 2002Published inissue 1 November 1987https://pubs.acs.org/doi/10.1021/jf00078a031https://doi.org/10.1021/jf00078a031research-articleACS PublicationsRequest reuse permissionsArticle Views159Altmetric-Citations18LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
MRI-based radiomics model for preoperative prediction of 5-year survival in patients with hepatocellular carcinoma (2020)

This radiomics model is a valid method to predict 5-year survival in patients with HCC and may be used to identify patients for clinical trials of perioperative therapies and for additional surveillance.
EFFECT OF DIETARY SILICON AND ALUMINUM ON SILICON AND ALUMINUM LEVELS IN RAT BRAIN (1987)

This preliminary study was undertaken to investigate the effect of dietary silicon and aluminum on levels of these elements in brain. Two ages of rats, 22 day and 10 month, were assigned to 1 of 4 diets: 1) low silicon; 2) low silicon plus aluminum; 3) silicon supplemented; and 4) silicon supplemented plus aluminum. Rats were 23 and 28 months old upon termination of the experiment. Twelve brain regions were analyzed for silicon and aluminum. Regional variations in silicon, which were independent of dietary silicon supplementation, suggest that silicon may be an essential element in brain. Aluminum supplementation decreased the silicon content in selected brain regions, including those thought to be involved in Alzheimer disease. A relationship has been established between silicon, aluminum and age. In 23-month rats, aluminum supplementation did not increase brain aluminum content. By contrast, in 28-month rats, aluminum supplementation of the low silicon diet increased brain aluminum content in most regions. No increase occurred in silicon supplemented groups of the same age. Dietary silicon supplementation thus appeared to be protective against aluminum accumulation in aging brain.
Relationship Between Independent Sitting Balance and Side of Hemiparesis (1986)

We conducted a retrospective chart audit of initial physical therapy evaluations to determine the incidence of sitting imbalance and its relationship to the side of weakness in hemiparetic patients. A review of the records of 105 patients revealed that the left side was predominantly affected in 52 patients and the right side in 53 patients. Age, time since onset, and proportion of men and women did not differ between the left and right hemiparetic patients. Most patients (81.0%) could sit independently, but 32.7% of those with left-sided weakness and 5.7% of those with right-sided weakness could not. A chi-square analysis revealed a significant relationship between the side of weakness and independent sitting balance (p less than .001). The phi-square test revealed the strength of this relationship to be .12. Patients with left hemiparesis are more likely to have difficulty with independent sitting than patients with right hemiparesis, which may affect their progress in rehabilitation.
Revisiting co-processing for hash joins on the coupled CPU-GPU architecture (2013)

Query co-processing on graphics processors (GPUs) has become an effective means to improve the performance of main memory databases. However, the relatively low bandwidth and high latency of the PCI-e bus are usually bottleneck issues for co-processing. Recently, coupled CPU-GPU architectures have received a lot of attention, e.g. AMD APUs with the CPU and the GPU integrated into a single chip. That opens up new opportunities for optimizing query co-processing. In this paper, we experimentally revisit hash joins, one of the most important join algorithms for main memory databases, on a coupled CPU-GPU architecture. Particularly, we study the fine-grained co-processing mechanisms on hash joins with and without partitioning. The co-processing outlines an interesting design space. We extend existing cost models to automatically guide decisions on the design space. Our experimental results on a recent AMD APU show that (1) the coupled architecture enables fine-grained co-processing and cache reuses, which are inefficient on discrete CPU-GPU architectures; (2) the cost model can automatically guide the design and tuning knobs in the design space; (3) fine-grained co-processing achieves up to 53%, 35% and 28% performance improvement over CPU-only, GPU-only and conventional CPU-GPU co-processing, respectively. We believe that the insights and implications from this study are initial yet important for further research on query co-processing on coupled CPU-GPU architectures.
[A portable heart rate histogram recorder]. (1977)

The experiment in question required required adult participants (with and without DCD) to walk up to and through differently sized apertures. The apertures were scaled to the shoulder width of the participants and were: 0.9, 1.1, 1.3, 1.5, 1.7, 1.9 and 2.1 times shoulder width. Movement was measured using a VICON system and by attaching marking on the left and right acroniom process and on C7. A number of different variables were measured during the approach and passage through the aperture. These included, walking speed, shoulder rotation while passing through the aperture and medio-lateral trunk movement during the approach. The full methods and the data are described in: (TBA once the paper is published) During everyday life we walk around busy environments, negotiating stationary and moving obstacles. This is usually performed effortlessly but actually involves complex skills to visually monitor the environment and control body movements. For individuals with coordination difficulties this presents a real challenge and can have a negative impact on safe participation at school or work and in everyday life. This project will consider several aspects of obstacle avoidance and navigation in children and adults with and without Developmental Coordination Disorder (DCD). DCD is characterized by everyday motor problems in the absence of sensory, intellectual or neurological impairment. The condition occurs in almost 2% of children and usually continues into adulthood. Primarily the project will focus on locomotion while negotiating a gap/aperture between obstacles such as that created by a doorway or parked cars. Such a task has both a perceptual element and a motor element. We plan to consider the perceptual element both in isolation and within a movement context. Finally the project will consider navigation of unpredictable or changing environments. The proposed research will further our understanding of the mechanisms underlying DCD and thereby assist in planning more effective interventions to support motor learning.
Organic dye photocatalyzed α-oxyamination through irradiation with visible light (2010)

Rose Bengal, an organic dye, was used as a visible light photocatalyst to investigate novel α-oxyamination reactions between 1,3-dicarbonyl compounds and a free radical (TEMPO). Compounds that are difficult to obtain such as quaternary fluorinated compounds were synthesized using this method. This visible light photocatalytic reaction can also be performed in water.
Synthesis and Aldol Reactivity of <i>O</i>- and <i>C</i>-Enolate Complexes of Nickel (2003)

The often facile C-/O-tautomerization of transition metal enolates is severely hindered in the cyclic Ni complexes 1 and 2, allowing the study of their individual reactivities. At room temperature only the O-bound tautomer, 2, reacts with aldehydes, giving rise to the corresponding addition products.
Phrases that signal workplace hierarchy (2012)

Hierarchy fundamentally shapes how we act at work. In this paper, we explore the relationship between the words people write in workplace email and the rank of the email's recipient. Using the Enron corpus as a dataset, we perform a close study of the words and phrases people send to those above them in the corporate hierarchy versus those at the same level or lower. We find that certain words and phrases are strong predictors. For example, "thought you would" strongly suggests that the recipient outranks the sender, while "let's discuss" implies the opposite. We also find that the phrases people write to their bosses do not demonstrate cognitive processes as often as the ones they write to others. We conclude this paper by interpreting our results and announcing the release of the predictive phrases as a public dataset, perhaps enabling a new class of status-aware applications.
Cerebrovascular Reactivity Impairment after Sport-Induced Concussion (2011)

These data suggest that normal CVR responses may be disrupted in the days immediately after occurrence of mTBI. Transcranial Doppler ultrasonography combined with expired gas measurements provides a useful method for assessing CVR impairment after mTBI. Further research, including serial monitoring after mTBI and analysis of CVR response to exercise, is warranted before any firm conclusions can be drawn.
[Change in the dependence of lymphocyte reactivity to phytomitogens on endogenous hormonal factors in experimental bacterial lesion of the prostate]. (1979)

The relationship between the blast lymphocyte transformation response (BLTR) to PHA P, Con A, PWM and 11-hydroxycorticosteroids (I) and the testosterone (II) levels in the blood plasma and the excretion of 17-ketosteroids with the urine were studied in 11 dogs with experimental urogenous prostatitis, provoked by Staphylococcus aureus, isolated from a patient with chronic prostatitis. Multiple correlation between the BLTR and hormonal factors was noted before the experiment. It was disturbed in a month and restored 2 months after the beginning of the experiment. Before the studies the relationships were mainly realized by direct correlation with 1 and 2 months after the experiment--due to the negative correlation with II. A homeostatic nature of the hormone lymphoid relationship with respect to 11-hydroxy-corticosteroids is suggested.
Rapid Quantification of Hepatitis B Virus DNA by Automated Sample Preparation and Real-Time PCR (2004)

Monitoring of hepatitis B virus (HBV) DNA in serum by molecular methods has become the standard for assessment of the replicative activity of HBV. Several molecular assays for the detection and quantification of HBV DNA have been described. However, they usually lack automated sample preparation. Moreover, those assays, which are based on PCR, are limited by a short dynamic range (2 to 3 log units). In the present study, the use of RealArt HBV LC PCR Reagents in conjunction with automated extraction on the COBAS AMPLIPREP analyzer was evaluated. Members of an HBV proficiency program panel were tested; linearity, interassay, and intra-assay variations were determined. The performance of the assay in a routine clinical laboratory was evaluated with a total of 117 clinical specimens. When members of the HBV proficiency program panel were tested by the new molecular assay, the results were found to be within +/-0.5 log unit of the results obtained by reference laboratories. Determination of linearity resulted in a quasilinear curve over more than 6 log units. The interassay variation of the RealArt HBV LC PCR Reagents by use of the automated sample preparation protocol ranged from 16 to 73%, and the intra-assay variation ranged from 9 to 40%. When clinical samples were tested by the new assay with the automated sample preparation protocol and the results were compared with those obtained by the COBAS AMPLICOR HBV MONITOR Test with manual sample preparation, the results for 76% of all samples with positive results by both tests were found to be within +/-0.5 log unit and the results for another 18% were found to be within between 0.5 and 1.0 log unit. In conclusion, the real-time PCR assay with automated sample preparation proved to be suitable for the routine molecular laboratory and required less hands-on time.
Reducing Aberrations in Rotating-Prism Compensators for Nonintermittent Motion Pictures (1952)

Optical compensators of the rotating-plate principle are widely used for their simplicity in motion picture equipment of various types. Despite many attempts, little improvement of their optical performance has been achieved. Some competent proposals to this aim and their optical limitations are briefly discussed. A novel type of compound compensator is theoretically investigated, utilizing two refracting “plates” whose indexes are respectively greater and less than one. It is shown how such a device can be practically realized and what requirements exist for the selection of suitable optical materials. Inasmuch as materials available at present permit the aberrations to be reduced by more than a factor of five, the proposed compound compensator seems to promise substantial improvement within practical reach.
Decision Making Model Supporting Emergency Medical Care (2009)

Accuracy in a pre-hospital trauma triage plays a critical role in reducing trauma mortality in a way that appropriately chooses a patient with severe injuries. Although various triage criteria have been devised and tested, there is no computer-based system developed that helps ambulance teams can make a decision in an appropriate manner. This research proposes to develop Expert Helper, an expert system which provides a user-friendly environment for the paramedics to decide whether patient to be posted to Critical Care Medical Centers (CCMC).