gebhart/patrepeval huggingface dataset:
8‐METHOXYPSORALEN PLUS UVA INDUCES THE 72 kDa HEAT SHOCK PROTEIN IN ORGAN‐CULTURED NORMAL HUMAN SKIN (1993)

The proteins induced by heat and other stressors, called heat shock proteins (HSP) or stress proteins, are considered to play a general role in protection from cellular injury. Exposure to UVA (320-400 nm) following application of 8-methoxypsoralen (8-MOP), termed PUVA is commonly used in the field of dermatology. In order to understand the induction of HSP in PUVA-treated human skin, indirect immunofluorescence using a monoclonal antibody specific for the 72 kDa HSP (HSP 72) was carried out in organ-cultured normal human skin that was treated with PUVA. When the organ-cultured skin was treated at 37 degrees for 1 h with 8-MOP at a final concentration of 10 or 100 micrograms/mL and exposed to UVA (51.3 kJ/m2), nuclear immunofluorescence of HSP 72 was detected in the epidermal cells 12 h after UVA irradiation. In contrast, the induction of HSP 72 was not detected either by UVA irradiation or 8-MOP treatment. These results suggest that PUVA treatment is one of the stressors for human skin, and DNA damage caused by PUVA induces HSP 72.
Characterization of Cotton-Polyester Blends by Electron Spectroscopy (ESCA) (1976)

Electron spectroscopy for chemical analyses (ESCA) was used to determine the percentage composition of cotton/polyester blend fabrics. The ratio of the C 1s /O 1s signal strengths was directly related to the composition of the blend. Additionally C 1a and O 1a peak shapes and full widths at half height varied as the amount of cotton in the blend changed.
Inhibitory Activity of Asarum sieboldii against Wood Rot Fungi on Traditional Paper, Hanji (2017)

Background: To investigate the possibility of using Asarum sieboldii as an environment-friendly fumigant for protecting organic cultural heritages, the inhibitory effect of A. sieboldii extract against wood rot fungi on Hanji was examined.Methods and Results: The physical, optical, and morphological properties of Hanji inoculated with Trametes versicolor and Tyromyces palustris, and exposed to the n-hexane fraction of A. sieboldii extract, were measured. The physical properties were expressed as weight loss, zero-span tensile strength and viscosity and the optical properties were depicted by luminance and chromaticity (L, a, and b). The results showed that, the n-hexane fraction of A. sieboldii extract inhibited the growth of fungi on Hanji, and preserved its condition. At a concentration of 25 ㎎, the n-hexane fraction of A. sieboldii extract maintained zero-span tensile strength, increased viscosity, and restricted discoloration of Hanji. It also was confirmed that the weight of fungi infested Hanji exposed to the extract did not decrease. Scanning electron microscopic images revealed that the spores and hyphae of T. versicolor and T. palustris were not present on Hanji during treatment with 25 ㎎ of the n-hexane fraction of A. sieboldii extract.Conclusions: These results indicate that the n-hexane fraction of A. sieboldii extract by virtue of its antifungal effectiveness may help in preserving Korean paper cultural heritages, including Hanji.
Design of Frameworks with Mixed Triangular and Octahedral Building Blocks Exemplified by the Structure of [Zn<sub>4</sub>O(TCA)<sub>2</sub>] Having the Pyrite Topology (2003)

Topologisches Lehrstück: Oktaedrische Bausteine (basische Zinkacetat-Template) bauen mit dreieckigen Bausteinen (Tricarbonsäuren) die anorganisch-organische Architektur MOF-150 auf (siehe Bild, links), die der Pyritstruktur (rechts) topologisch entspricht. Die Durchdringung zweier unabhängiger Gitter ergibt die erste vollständig verkettete Struktur mit gemischter Koordination. Entscheidend dafür sind die selbstdualen Eigenschaften der Pyritstruktur (TCA=4,4′,4′′-Tricarboxytriphenylamin).
Effect of implant drill characteristics on heat generation in osteotomy sites: a pilot study (2010)

Within the limitations of this pilot study, the observations herein suggest that reduction in contact area between the drill and bone reduces heat induction. Further studies to optimize drill/bone contact dimensions are needed.
Planning-based visual programming system for sequence control (2002)

The paper presents a planning based visual programming system for sequence control program specification design (VIPS/S-SFCD). VIPS/S-SFCD features an example based programming technique in which designers specify the initial states and goal states of machines using visual representations, and a planning method that infers machine actions and generates the control program specifications. This method is based on the state space model and has the scope to make the searches on the model efficient. We used the planner of VIPS/S-SFCD to experimentally generate control program specifications for actually existing steel plants. The experimental results showed that the quality of control program specifications generated by VIPS/S-SFCD was the same as the ones generated by a design specialist, and the time required for designing control programs was much shorter. According to our experiments, VLPS/S-SFCD can reduce the design time of control programs to 1/3.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Coping as a Multisystem Construct Associated With Pathways Mediating HIV-Relevant Immune Function and Disease Progression (2008)

We review psychoneuroimmunological research linking coping with HIV disease progression and its indicators, as well as with viral and host factors that may mediate or contribute to HIV progression. Our perspective on coping broadly encompasses the attempts of multiple mental and biological systems to adapt to changing internal and environmental conditions and to reestablish homeostasis. Accordingly, we discuss studies within four dimensions of coping: cognitive (appraisals, expectancies, and explanatory style), emotional (the Type C coping pattern and related constructs), active-passive strategies and behavior patterns, and physiological (autonomic reactivity and recovery). Finally, we present a model that integrates key studies linking coping with HIV prognostic indicators and clinical disease progression. Based on empirical evidence, the model suggests plausible mechanisms by which coping may be connected to HIV progression/antiprogression factors and immunopathogenesis to affect HIV clinical progression.
ChemInform Abstract: AETHINYLIERUNG VON 1,2‐O‐ISOPROPYLIDEN‐ALPHA‐D‐XYLO‐PENTODIALDOSE‐DERIVATEN, EINE SYNTHESE VON URONSAEUREN (1971)

Abstract Einwirkung von Formaldehyd/Natriumperjiodat auf 1,2‐O‐Isopropyliden‐α‐D‐glucofuranose (I) ergibt ein Gemisch aus dem Dimeren (II) und der 3,5‐O‐Methylen‐Verbindung (III) (Gesamtausbeute 59%).
ChemInform Abstract: UNTERSUCHUNGEN AN HETEROCYCLEN 12. MITT. TRICHLOR‐6‐CYAN‐PYRIMIDIN (1970)

Abstract Das Nitropyrimidin (I) reagiert mit Phosphorylchlorid in Gegenwart von Diäthylanilin (II) unerwarteterweise zum Trichlor‐cyanderivat (III) (30% Ausbeute), dem Amid (IV) (19,5%) und wenig der Anilinoverbindung (V) (0,5%).
Dual voltage source inverter topology extending machine operating range (2012)

Field weakening operation of an electrical machine is a conventional method to extend the angular velocity range of a system above the peak output voltage of the inverter. A downside, however, is that an increased reactive current is required that creates losses but no output torque. A dual voltage source inverter topology is proposed, capable of driving an electrical machine without weakening its field in an extended speed range. For this purpose, a second inverter fed by a capacitor only is connected to the open-end side of the machine windings. Charging the floating capacitors is realized by adding an AC zero sequence current to the regular machine currents. The operating principles of the presented topology are demonstrated, showing their possible advantages when driving an electrical machine. Simulation results confirm the proposed ideas.
Patella Fracture During Rehabilitation After Bone-Patellar Tendon-Bone Anterior Cruciate Ligament Reconstruction: 2 Case Reports (2009)

During rehabilitation following ACL reconstruction using BPTB autograft, clinicians should consider the need to balance the sometimes-competing goals of improving quadriceps strength while providing protection to the healing graft, minimization of patellofemoral pain, and protection of the patellar donor site.
ChemInform Abstract: From Intermolecular Alcohol Additions on a Double Bond to Electrocyclizations of Non‐Activated γ,δ‐Unsaturated Alcohols: An Easy Synthesis of Tetrahydrofurans. (1997)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Quantative Analysis of Yttrium in Steel by Solution Spectrographic Analysis (1965)

In order to carry out the quantative analysis yttrium in steel, a spectrographic method was applied. The solution technique with a rotating disk electrode was used, because solid standard samples for the spectrographic analysis of yttrium were not prepared and the use chipped samples was intended.Using the Carl-Zeiss QU 24 spectrograph, effects of discharge conditions, dissolving acids (HCl, HNO3, H2SO4) and electrodes (graphite, Cu) on the sensitivity and precision of the yttrium spectral line were studied.The result showed the optimum analytical condition to be as follows:(This article is not displayable. Please see full text pdf.) The reproducibility of the solution method was 3.9% in terms of the coefficient of variance in the range from 0.01%Y to 0.7%Y.The Ti content is necessary to be less than 0.01%, because Y 3242.3 Å is affected by Ti 3242.0 Å.If the Ti content is more than 0.01%, another line pair Fe 3659.5/Y 3664.6 can be applied. In this case, however, the reproducibility is worse in some measure than that of Fe 3205.4/Y 3242.3.Then, as solid steel samples which contain yttrium were obtained, the content of yttrium was determined by the solution spectrographic method mentioned above and then direct excitation method of solid steel was studied by using those samples for standardization.It was found that the same excitation conditions with those of the solution spectrographic method was also available favorably in this case, and the sensitivity and precision were almost same to those of the solution spectrographic method.
A machine independent WCET predictor for microcontrollers and DSPs [worst case execution time] (2002)

This paper describes a method for analyzing and predicting the timing properties of a program fragment. The paper first presents a language implemented to describe a processor's architecture and a static worst case execution time (WCET) estimation method is then presented. The timing analysis starts by compiling a processor's architecture program followed by the disassembling of the program fragment. The assembler program is then decomposed into basic blocks and a call graph is generated. These data are later used to evaluate the pipeline hazards and cache miss that penalize the real-time performance. Finally, some experimental results of using the developed tool to predict the WCET of code segments with some Intel microcontrollers are presented.
Electrically Switchable Organic Surface Plasmon Source (2008)

Get PDF Email Share Share with Facebook Tweet This Post on reddit Share with LinkedIn Add to CiteULike Add to Mendeley Add to BibSonomy Get Citation Copy Citation Text D. M. Koller, A. Hohenau, H. Ditlbacher, N. Galler, F. R. Aussenegg, A. Leitner, J. R. Krenn, and E. J. W. List, "Electrically switchable organic surface plasmon source," in Frontiers in Optics 2008/Laser Science XXIV/Plasmonics and Metamaterials/Optical Fabrication and Testing, OSA Technical Digest (CD) (Optica Publishing Group, 2008), paper MThD2. Export Citation BibTex Endnote (RIS) HTML Plain Text Citation alert Save article
Studies of advanced fuel injection concepts for diesel engines. (Reannouncement with new availability information) (1989)

A shock tube apparatus developed for the study of diesel injector performance is introduced. The results of preliminary tests of a common rail system`s electronically controlled, accumulator type injectors, adopted as representative of the state-of-the-art in this technology, are reported. Salient features of advanced concepts, designed to minimize the formation of particulates, are presented. Our studies are based on the premise that the demand for the elimination of harmful emissions can be met by controlling combustion in engines, so that the formation of pollutants is significantly reduced. For diesel engines this means principally the inhibition in the production of particulates. In principle it should be possible to accomplish this by executing the process of combustion in such a wavy that the action of diffusion flames - the mode of the process that takes place today, as a rule, in diesel engines - is effectively curbed down, whereas, in the absence of their stabilizing influence, the system is controlled by external, electronically monitored means.
Metallic and atomic approximations at the Schottky barrier interfaces (1984)

Stimulated by the work of Zur, McGill, and Smith (ZMS), we have undertaken a broad examination of the ‘‘potential normalization’’ conditions at the metal–semiconductor interface. We have made calculations using a metallic approximation and the model of Bardeen. Strong overall agreement is found with the results of ZMS; however, the details depend on the specific parameters used in the calculations. In particular, parameters were identified which give different pinning positions on n- and p-type semiconductor materials. Experimentally, Cs is found to be in strong disagreement with any ‘‘metallic’’ approximation at the interface; rather, it is shown that the experimental and theoretical understanding of Cs on solids indicates that an atomic model for the last atomic layer of Cs (with some fixed charge due to the induced Cs atomic dipole at the interface) is a more appropriate approximation than the metallic approximation used by ZMS and ourselves. Experimental results for thick noble metals (Au, Cu, and Ag) deposited in situ on clean GaAs(110) formed by cleaving in UHV are reported. These give a pinning position at the donor level as do properly analyzed PES measurements on thin (sub- to full-monolayer) deposits of noble metals on GaAs. An atomic explanation based on the large electron affinity of the noble metals is suggested and this is related to the interfacial chemistry. In contrast, significant differences are found between the thin and thick pinning positions of Al on GaAs in general agreement with the metallic approximations of ZMS and ourselves.
Interleukin-1β Transfer across the Blood–Brain Barrier in the Ovine Fetus (2015)

Pro-inflammatory cytokines contribute to hypoxic-ischemic brain injury. Blood-brain barrier (BBB) dysfunction represents an important component of hypoxic-ischemic brain injury in the fetus. Hypoxic-ischemic injury could accentuate systemic cytokine transfer across the fetal BBB. There has been considerable conjecture suggesting that systemic cytokines could cross the BBB during the perinatal period. Nonetheless, evidence to support this contention is sparse. We hypothesized that ischemia-reperfusion increases the transfer of systemic interleukin-1β (IL-1β) across the BBB in the fetus. Ovine fetuses at 127 days of gestation were studied 4 hours after 30 minutes of bilateral carotid artery occlusion and compared with a nonischemic group. Recombinant ovine IL-1β protein was expressed from an IL-1β pGEX-2 T vector in E. coli BL-21 cells and purified. The BBB function was quantified in 12 brain regions using a blood-to-brain transfer constant with intravenous (125)I-radiolabeled IL-1β ((125)I-IL-1β). Interleukin-1β crossed the intact BBB in nonischemic fetuses. Blood-to-brain transport of (125)I-IL-1β was higher (P<0.05) across brain regions in fetuses exposed to ischemia-reperfusion than nonischemic fetuses. We conclude that systemic IL-1β crosses the intact fetal BBB, and that ischemia-reperfusion increases transfer of this cytokine across the fetal BBB. Therefore, altered BBB function after hypoxia-ischemia facilitates entry of systemic cytokines into the brain of the fetus.
Genotype???phenotype associations for common CYP3A4 and CYP3A5 variants in the basal and induced metabolism of midazolam in European- and African-American men and women (2003)

CYP3A activity in adults varies between individuals and it has been suggested that this has a genetic basis, possibly related to variant alleles in CYP3A4 and CYP3A5 genes. Accordingly, genotype-phenotype associations were investigated under constitutive and induced conditions. Midazolam's systemic and oral clearances, and the erythromycin breath test (ERBT) were determined in 57 healthy subjects: 23 (11 men, 12 women) European- and 34 (14 men, 20 women) African-Americans. Studies were undertaken in the basal state and after 14-15 days pretreatment with rifampin. DNA was characterized for the common polymorphisms CYP3A4*1B, CYP3A5*3, CYP3A5*6 and CYP3A5*7 by direct sequencing, and for exon 21 and exon 26 variants of MDR1 by allele-specific, real-time polymerase chain reaction. In 95% of subjects, the basal systemic clearance of midazolam was unimodally distributed and variability was less than four-fold whereas, in 98% of the study population, oral clearance varied five-fold. No population or sex-related differences were apparent. Similar findings were observed with the ERBT. Rifampin pretreatment markedly increased the systemic (two-fold) and oral clearance (16-fold) of midazolam, and the ERBT (two-fold) but the variabilities were unchanged. No associations were noted between these phenotypic measures and any of the studied genotypes, except for oral clearance and its fold-increase after rifampin. These were related to the presence of CYP3A4*1B and the inversely linked CYP3A5*3 polymorphism, with the extent of induction being approximately 50% greater in CYP3A5*3 homozygotes compared to wild-type subjects. In most healthy subjects, variability in intestinal and hepatic CYP3A activity, using midazolam as an in-vivo probe, is modest and common polymorphisms in CYP3A4 and CYP3A5 do not appear to have important functional significance.
Elevation of KL-6, a lung epithelial cell marker, in plasma and epithelial lining fluid in acute respiratory distress syndrome (2004)

KL-6 is a pulmonary epithelial mucin more prominently expressed on the surface membrane of alveolar type II cells when these cells are proliferating, stimulated, and/or injured. We hypothesized that high levels of KL-6 in epithelial lining fluid and plasma would reflect the severity of lung injury in patients with acute lung injury (ALI). Epithelial lining fluid was obtained at onset (day 0) and day 1 of acute respiratory distress syndrome (ARDS)/ALI by bronchoscopic microsampling procedure in 35 patients. On day 0, KL-6 and albumin concentrations in epithelial lining fluid were significantly higher than in normal controls (P < 0.001), and the concentrations of KL-6 in epithelial lining fluid (P < 0.002) and in plasma (P < 0.0001) were higher in nonsurvivors than in survivors of ALI/ARDS. These observations were corroborated by the immunohistochemical localization of KL-6 protein expression in the lungs of nonsurvivors with ALI and KL-6 secretion from cultured human alveolar type II cells stimulated by proinflammatory cytokines. Because injury to distal lung epithelial cells, including alveolar type II cells, is important in the pathogenesis of ALI, the elevation of KL-6 concentrations in plasma and epithelial lining fluid could be valuable indicators for poor prognosis in clinical ALI.
New Methods and Reagents in Organic Synthesis. 68. Reaction of Thioketones with Lithium Trimethylsilyldiazomethane (1987)

Reaction of thioketones w i t h l i t h i u m t r i m e t h y l s i l y l d i a z o m e t h a n e sffords alkynes, vinylsilanes.1.2.3-thiadiarolines.o r 1.2.3-thiadiazoles depending upon substrates and reaction solvents.W e have already demonstrated t h a t the l i t h i u m s a l t of trimethylsllyldiazomethane (TMSC(Li)N2), a useful [C-N-N] azole synthon.' smoothly reacts v i t h thiocarbonyl compounds such as thionoesters.dithioesters, and carbon d i s v l f i d e t o g i v e %substituted 1.2.3-thiadia~ales.~We now r e p o r t the r e a c t i o n o f t h i o k e t o n e s 1 w i t h TMSC(Li)N2, w h i c h gives v a r i o u s p r o d u c t s 2-5 depending upon substrates and reaction solvents (Scheme 1). R y / R+ Me,SiC(Li)N, 8 I
Antagonistic Effect of Toll-Like Receptor Signaling and Bacterial Infections on Transplantation Tolerance (2009)

The induction of donor-specific tolerance remains a major goal in the field of transplantation immunology. Therapies that target costimulatory molecules can induce tolerance to heart and pancreatic islet allografts in mouse models, but fail to do so after transplantation of skin or intestinal allografts. We have proposed that organs colonized by commensal bacteria such as skin, lung, and intestine may be resistant to such therapies as a result of bacterial translocation at the time of transplantation, which may promote antigen-presenting cell maturation and the production of proinflammatory cytokines, consequently enhancing responses of alloreactive T cells. Our results indicate that the inability to sense signaling by most toll-like receptors (TLRs), as well as by interleukin-1R and -18R, as a result of genetic ablation of myeloid differentiation factor 88 promotes the acceptance of skin allografts. Conversely, TLR signals and infections by a model bacterium, Listeria monocytogenes (LM), at the time of transplantation can prevent the induction of transplantation tolerance. The effects of the TLR9 agonist CpG are myeloid differentiation factor 88-dependent, whereas the prorejection capacity of LM depends on the intracellular sensing of LM and the production of type I interferon. Therefore, transiently targeting these innate, proinflammatory pathways may have therapeutic value to promote transplantation tolerance.
Long-term Death Rates, West Nile Virus Epidemic, Israel, 2000 (2005)

We studied the 2-year death rate of 246 adults discharged from hospital after experiencing acute West Nile Virus infection in Israel during 2000. The age- and sex-adjusted death rates were significantly higher than in the general population. This excess was greater for men. Significant adverse prognostic factors were age, male sex, diabetes mellitus, and dementia.