gebhart/patrepeval huggingface dataset:
Glycosynaptic microdomains controlling tumor cell phenotype through alteration of cell growth, adhesion, and motility (2009)

Glycosphingolipids (GSLs) GM3 (NeuAcalpha3Galbeta4Glcbeta1Cer) and GM2 (GalNAcbeta4[NeuAcalpha3]Galbeta4Glcbeta1Cer) inhibit (i) cell growth through inhibition of tyrosine kinase associated with growth factor receptor (GFR), (ii) cell adhesion/motility through inhibition of integrin-dependent signaling via Src kinases, or (iii) both cell growth and motility by blocking "cross-talk" between integrins and GFRs. These inhibitory effects are enhanced when GM3 or GM2 are in complex with specific tetraspanins (TSPs) (CD9, CD81, CD82). Processes (i)-(iii) occur through specific organization of GSLs with key molecules (TSPs, caveolins, GFRs, integrins) in the glycosynaptic microdomain. Some of these processes are shared with epithelial-mesenchymal transition induced by TGFbeta or under hypoxia, particularly that associated with cancer progression.
3D reconstruction and measurement of indoor object using stereo camera (2011)

This paper implements a study of 3D reconstruction and measurement of indoor objects using binocular stereo camera. First, SIFT feature are extracted from both images and the matching points are found. RANSAC method is applied to eliminate wrong matching points. Second, two stereo images are rectified and generated disparity mapping. Finally, the depth mapping and 3D information of each pixel are derived. This method is applied to reconstruct and measure the true object in indoor environment.
Valuation, Optimal Asset Allocation and Retirement Incentives of Pension Plans (1997)

Journal Article Valuation, Optimal Asset Allocation and Retirement Incentives of Pension Plans Get access Suresh Sundaresan, Suresh Sundaresan Columbia University Address all correspondence to Suresh Sundaresan, Graduate School of Business. Columbia University, New York, NY 10027. Search for other works by this author on: Oxford Academic Google Scholar Fernando Zapatero Fernando Zapatero Centre de Investigacion Economica, ITAM Search for other works by this author on: Oxford Academic Google Scholar The Review of Financial Studies, Volume 10, Issue 3, July 1997, Pages 631–660, https://doi.org/10.1093/rfs/10.3.631 Published: 03 April 2015
Characterization of Blood‐Group‐H‐Active Ceramide Tetrasaccharide from Hog‐Stomach Mucosa (1974)

A fucose‐containing ceramide tetrasaccharide exhibiting blood‐group‐H activity was isolated from a lipid extract of hog stomach mucosa by column fractionations on DEAE‐cellulose and Florisil followed by purification on thin‐layer plates. By partial acid hydrolysis, sequential degradation with specific glycosidases and methylation analysis, the structure of this glycolipid was identified as: Fucα1 →, 2Galα1 → 3Galβ1 → 4Glc1 → 1Cer; where Fuc = fucose; Gal = glucose; Gal = glucose and Cer = ceramide.
What Happens to Spo<sub>2</sub>During Air Medical Crew Intubations? (2006)

Documentation of crew-recorded peri-ETI SpO2 nadir is a useful and practical prehospital data point.
Outer membrane nanovesicles of gram-negative bacteria Aeromonas hydrophila and Aeromonas salmonicida (2011)

Aeromonas hydrophila and A. salmonicida grown in pure cultures were found to secrete extracellular membrane nanovesicles into the environment. Outer membrane nanovesicle preparations were isolated by differential centrifugation and ultrafiltration and visualized by transmission electron microscopy applying the negative staining technique. Membrane nanovesicle size (10–300 nm) and ultrastructure were determined. The vesicles were especially numerous around bacteria at the edge of small colonies. The process of the vesicle budding off the bacterial cell was observed. On ultrathin sections of rat intestine, outer membrane nanovesicles were revealed among bacterial aggregates of various species of parietal microorganisms. Short chains of such vesicles were also detected inside the glycocalyx between the microvilli of the apical surface of the intestine epitheliocytes. On the basis of the results, together with the literature data, the secretion of the outer membrane nanovesicles by pathogenic gram-negative bacteria, such as A. hydrophila and A. salmonicida, is proposed as a possible mechanism of pathogenesis leading to the host disease, as well as a means for cellular interactions both within the prokaryote population and between the bacteria and the host organism.
J. Vialatoux, La morale de Kant, Coll. "Initiation Philosophique", n°22, Paris, P.U.F., 1956. (1960)

info:eu-repo/semantics/published
Ontological Pathfinding (2016)

Recent years have seen a drastic rise in the construction of web-scale knowledge bases (e.g., Freebase, YAGO, DBPedia). These knowledge bases store structured information about real-world people, places, organizations, etc. However, due to limitations of human knowledge and information extraction algorithms, these knowledge bases are still far from complete. In this paper, we study the problem of mining first-order inference rules to facilitate knowledge expansion. We propose the Ontological Pathfinding algorithm (OP) that scales to web-scale knowledge bases via a series of parallelization and optimization techniques: a relational knowledge base model to apply inference rules in batches, a new rule mining algorithm that parallelizes the join queries, a novel partitioning algorithm to break the mining tasks into smaller independent sub-tasks, and a pruning strategy to eliminate unsound and resource-consuming rules before applying them. Combining these techniques, we develop the first rule mining system that scales to Freebase, the largest public knowledge base with 112 million entities and 388 million facts. We mine 36,625 inference rules in 34 hours; no existing approach achieves this scale.
Regulation of cytokine release from mononuclear cells by the iron- binding protein lactoferrin (1992)

The iron-binding protein lactoferrin (Lf) is a constituent of neutrophil secondary granules and is discharged into the surrounding medium when neutrophils are activated. Lf released from neutrophils phagocytosing opsonized particles inhibits proliferation of mixed lymphocyte cultures (MLC) and has also been shown to inhibit granulopoiesis, suppress antibody production, and regulate natural killer cell activity. All of these processes are controlled by cytokines, suggesting that Lf may modulate immune responses by inhibiting cytokine activity. When MLC were cultured in round-bottomed wells to crowd the cells together, Lf, 50% saturated with iron, inhibited both proliferation and interleukin-2 (IL-2) release into the supernatants. Inhibition was concentration-dependent and lost at concentrations of Lf greater than 10(-12) mol/L. Lf at 10(-10) mol/L inhibited release of tumor necrosis factor-alpha (TNF) and interleukin-1 beta (IL-1) into MLC supernatants, as well as inhibiting IL-2 release. TNF in the supernatant was significantly reduced at 5 and 24 hours, becoming less and losing significance by 72 hours. IL-1 in the supernatant was not significantly reduced at 5 and 24 hours, becoming significant at 48 and 72 hours. IL-2 was significantly reduced at 48 and 72 hours and followed the same time course as proliferation. Inhibition was blocked by specific antiserum to Lf, but not by a preimmune serum. Lf, 10(-10) mol/L, also inhibited the production of TNF (49.15% +/- 7.98%; n = 10, P = .032) and IL-1 (42.67% +/- 6.72%; n = 6, P = .032) from endotoxin-stimulated mononuclear cells. As with MLC, inhibition was dose-dependent and abrogated by specific antiserum. Lf did not block the biological action of TNF, IL-1, or IL-2 in specific assays using cytokine-sensitive cell lines. These data suggest that Lf, released from activated neutrophils, acts as a negative feedback mechanism to prevent recruitment and activation of leukocytes in sites of inflammation.
Discrete Fourier transform using summation by parts (2005)

An algorithm for evaluating the Discrete Fourier Transform (DFT) at particular output frequency is derived using a technique called summation by parts (SBP). This technique is shown to reduce the number of multiplications and the number of bits per multiplicative coefficient needed to implement the DFT. For many transform lengths, only two one-bit multiplications or simple memory shifts are needed to implement the DFT. When the DFT length is prime, a SBP algorithm designed for a fixed output frequency index can be used to evaluate the DFT at any other non-zero output frequency index simply by appropriately changing the order of the input sequence.
Continuous Cocurrent Extraction of Milk Fat by Supercritical Carbon Dioxide (1994)

Performance of a continuous cocurrent supercritical fluid extraction column for processing of anhydrous milk fat (AMF) was determined. The extract loading increased and the extraction yield decreased as the superficial velocity of AMF increased. The maximum solubility of AMF in at 4/3,500 psig was 0.0195g/g. The increase of the carbon dioxide density enhanced the solubility of milk fat and decreased the cholesterol concentration in the extract. Three operation conditions, such as recycle , reflux, and temperature gradient of extraction column, were tested. More short-chain fatty acvids were extracted by the reflux operation . Longchain fatty acids and thehighest ratio fo long-chain unsaturated to saturated fatty acids were also obtained in the raffinate phase with refluex.
Coexistence analysis of asynchronous digital subscriber lines with different sampling rate and carrier frequency spacing (2014)

G.fast is the next-generation digital subscriber line (DSL) technology targeting bit-rates of up to 1 Gbps. Very high speed digital subscriber line 2 (VDSL2) is the the latest DSL technology delivering bit-rates of up to 100 Mbps. Replacement of VDSL2 by G.fast modems will be gradual, which implies coexistence of these two systems. G.fast and VDSL2 use different symbol durations, carrier frequency spacings, and sampling rates, which results in inter-carrier and inter-symbol interference (ICSI). We derive an analytical model of ICSI capturing these differences in modulation. Furthermore, through simulations we show that for particular network topologies coexistence of the two systems results in significant bit-rate losses compared to an interference-free scenario.
근린생활시설의 운영유형에 따른 열원방식별 에너지사용량 비교분석 (2016)

To reduce the energy consumptions in buildings, the government of South Korea, and the Korea District Heating Corporation have recommended the adoption of gas engine-driven heat pump (GHP) using natural gas, and district heating and cooling. Analyzed in the present study are the operation times for each purpose of use regarding various operation types of neighborhood living facility through field surveys. The energy consumptions for each heat source, and by the purpose of use were comparatively analyzed through EnergyPlus. As a result, the annual energy consumption of an FCU-type (fan coil unit type) district heating and cooling was lower than the annual energy consumption of the GHP. Therefore, it was concluded that the neighborhood living facilities with various operation types are more suited by the FCU-type district heating and cooling system.
A gem-Effect in the Addition of 2,4-Dinitrobenzenesulfenyl Chloride to γ,δ-Unsaturated Acids (1954)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTA gem-Effect in the Addition of 2,4-Dinitrobenzenesulfenyl Chloride to γ,δ-Unsaturated AcidsMarcello De Moura CamposCite this: J. Am. Chem. Soc. 1954, 76, 17, 4480–4481Publication Date (Print):September 1, 1954Publication History Published online1 May 2002Published inissue 1 September 1954https://pubs.acs.org/doi/10.1021/ja01646a065https://doi.org/10.1021/ja01646a065research-articleACS PublicationsRequest reuse permissionsArticle Views46Altmetric-Citations14LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Protection from autoimmune diabetes by adjuvant therapy non‐obese diabetic mouse: The role of interleukin‐4 and interleukin‐10 (1997)

Insulin-dependent diabetes mellitus (IDDM) is an autoimmune disease that is characterized by the destruction of insulin-producing beta-cells in the pancreatic islets. A single administration of CFA prevents clinical hyperglycaemia in non-obese diabetic (NOD) mice. We have previously shown that CFA administration does not eliminate insulitis in the pancreas of the treated animals, but diverts the disease process from a destructive to a non-destructive pathway. We provide evidence that this phenomenon may be under cytokine control. Neutralizing monoclonal antibodies against IL-4 and IL-10 were injected, singularly or in combination, into CFA-treated NOD mice. Antibody treatment did not lead to the development of overt diabetes; however, a marked impairment of glucose tolerance was shown in about one half of the mice treated with a combination of the two antibodies at the end of the study. This functional abnormality correlated with the histological loss of pancreatic islet tissue. These studies suggest a role for IL-4 and IL-10 in CFA-induced protection from diabetes in the NOD mouse. They also suggest that, in this animal model, the nature of the autoimmune response to islet tissue (either destructive or non-destructive) may reflect the relative proportion of Th1- and Th2-type cytokines produced in the lesions.
Discriminant malware distance learning on structural information for automated malware classification (2013)

The voluminous malware variants that appear in the Internet have posed severe threats to its security. In this work, we explore techniques that can automatically classify malware variants into their corresponding families. We present a generic framework that extracts structural information from malware programs as attributed function call graphs, in which rich malware features are encoded as attributes at the function level. Our framework further learns discriminant malware distance metrics that evaluate the similarity between the attributed function call graphs of two malware programs. To combine various types of malware attributes, our method adaptively learns the confidence level associated with the classification capability of each attribute type and then adopts an ensemble of classifiers for automated malware classification. We evaluate our approach with a number of Windows-based malware instances belonging to 11 families, and experimental results show that our automated malware classification method is able to achieve high classification accuracy.
ConfluxDB (2014)

Lazy replication with snapshot isolation (SI) has emerged as a popular choice for distributed databases. However, lazy replication often requires execution of update transactions at one (master) site so that it is relatively easy for a total SI order to be determined for consistent installation of updates in the lazily replicated system. We propose a set of techniques that support update transaction execution over multiple partitioned sites, thereby allowing the master to scale. Our techniques determine a total SI order for update transactions over multiple master sites without requiring global coordination in the distributed system, and ensure that updates are installed in this order at all sites to provide consistent and scalable replication with SI. We present ConfluxDB, a PostgreSQL-based implementation of our techniques, and demonstrate its effectiveness through experimental evaluation.
Measurement of Quality of Experience of Video-on-Demand Services: A Survey (2015)

Video-on-demand streaming services have gained popularity over the past few years. An increase in the speed of the access networks has also led to a larger number of users watching videos online. Online video streaming traffic is estimated to further increase from the current value of 57% to 69% by 2017, Cisco, 2014. In order to retain the existing users and attract new users, service providers attempt to satisfy the user's expectations and provide a satisfactory viewing experience. The first step toward providing a satisfactory service is to be able to quantify the users' perception of the current service level. Quality of experience (QoE) is a quality metric that provides a holistic measure of the users' perception of the quality. In this survey, we first present a tutorial overview of the popular video streaming techniques deployed for stored videos, followed by identifying various metrics that could be used to quantify the QoE for video streaming services; finally, we present a comprehensive survey of the literature on various tools and measurement methodologies that have been proposed to measure or predict the QoE of online video streaming services.
Effect of Oral Administration Involving a Probiotic Strain of Lactobacillus reuteri on Pro-Inflammatory Cytokine Response in Patients with Chronic Periodontitis (2014)

This study aimed at evaluation of pro-inflammatory cytokine response (TNF-α, IL-1β and IL-17) in patients with chronic periodontitis administered per os with a probiotic strain of Lactobacillus reuteri. In the 38 adult patients with moderate chronic periodontitis, professional cleaning of teeth was performed. Two weeks after performing the oral hygienization procedures, clinical examination permitted to distinguish a group of 24 patients (Group 1) in whom treatment with probiotic tablets containing L. reuteri strain, producing hydrogen peroxide (Prodentis), was conducted. In the remaining 14 patients, no probiotic tablet treatment was applied (the control group; Group 2). From all patients in two terms, gingival crevicular fluid (GCF) was sampled from all periodontal pockets. Estimation of TNF-α, IL-lβ and IL-17 in GCF was performed using the ELISA method. After completion of the therapy with probiotic tablets, 18 (75%) of the patients of Group 1 have manifested a significant decrease in levels of studied pro-inflammatory cytokines (TNF-α, IL-1β and IL-17). In parallel, we have detected an improvement of clinical indices [sulcus bleeding index (SBI), periodontal probing depth (PPD), clinical attachment level (CAL)]. At individuals of Group 2 levels of studies, pro-inflammatory cytokines and clinical indices (SBI, PPD, CAL) were significantly higher than in Group 1. Results obtained in this study indicate that application of oral treatment with tablets containing probiotic strain of L. reuteri induces in most patients with chronic periodontitis a significant reduction of pro-inflammatory cytokine response and improvement of clinical parameters (SBI, PPD, CAL). Therefore, such an effect may result in a reduced activity of the morbid process.
Biochemical characterization of rat colonic mucins secreted in response to Entamoeba histolytica (1992)

Invasion of the colonic mucosa by Entamoeba histolytica trophozoites is preceded by colonic mucus depletion. The aim of our studies was to determine whether E. histolytica caused a differential secretion of mucin species in a rat colonic loop model. Mucus secretion in response to amoebae was followed by release of acid-precipitable 3H-glucosamine metabolically labelled glycoproteins and in vitro labelling of glycoprotein secretion with NaB3H4. The secretory response consisted of high-Mr goblet cell mucins and an increase in the secretion of low-Mr nonmucin glycoproteins as determined by Sepharose 4B column chromatography. High-Mr mucins subfractionated by Cellex-E (ECTEOLA) ion-exchange chromatography demonstrated a minor neutral and a major acidic mucin (greater than 98%) species. Marked differences between the neutral and acidic mucin species were indicated by immunogenicity and amino acid compositions. Thin-section histochemistry of rat colons confirmed secretion of neutral and acidic mucins in response to E. histolytica and demonstrated secretory activity from goblet cells from both the crypts and interglandular epithelium. E. histolytica mucus secretagogue activity was generalized and may function to deplete the host's protective mucus layer, facilitating invasion by the parasites.
A 368 × 184 Optical Under-Display Fingerprint Sensor With Global Shutter and High-Dynamic-Range Operation (2020)

This study proposes a 368 ×184 optical under-display fingerprint sensor designed and prototyped using 0.11-μm CIS technology. The prototype sensor with global shutter operation and an ADC-embedded in an 8-pixel configuration features low noise, low-power consumption, fast response time, and a smaller signal processing circuit area. Two sets of memory (184 × 92 bytes) are also embedded in the pixel array to save external memory cost. A dynamic range of 126 dB is achieved with 8-segment auto exposure and dark level adjustment with programmable gain control. The prototype fingerprint sensor was successfully embedded in a mobile phone for functional verification, and the power consumption was only 25 mW with a 3.3 V supply voltage. The sensor has a chip size of 9.74 mm ×4.6 mm, a resolution of 1154 dpi, and a sensing area of 73%.
A practical analysis of EAP authentication methods (2010)

In the context of a growing concern for data security, network access control has become an important part of every network security system. The purpose of this paper is to provide a comparison between different EAP Methods that can be used with IEEE 802.1x, Port Based Network Access Control, standard as a means of protecting a computer network against unauthorized access. Three of the most common methods, EAP-MD5, EAP-TLS and PEAP, are compared with regard to time and packet performance both between each other and against a default situation, with no access control in place. The factors considered, authentication and reauthentication time, packet loss during reconnection and throughput are measured in a specially designed test environment using test equipment capable of accurate measurement of time in the range of milliseconds and constant high rate traffic generation.
Skew variability in 3-D ICs with multiple clock domains (2011)

The effect of process variations on the clock skew in three dimensional (3-D) circuits with multiple clock domains is investigated. In 3-D ICs, the combined effect of inter-die and intra-die process variations should be considered in the design of clock distribution networks. A statistical clock skew model incorporating spatially correlated intra-die process variations is employed to describe this effect. The clock skew is shown to change in different ways with the allocation of the clock domains within the 3-D circuit. Various schemes to assign the clock domains are investigated. Different scenarios of inter-die and intra-die process variations and an intra-die spatial correlation model are applied to these schemes. An approach where each physical plane corresponds to a single clock domain is shown to be inferior to other clocking schemes for specific variation scenarios. Tradeoffs between the number of clock domains within a physical plane and the number of planes a clock tree spans are discussed and related design guidelines are offered.