gebhart/patrepeval huggingface dataset:
The <i>Pseudomonas aeruginosa</i> Flagellar Cap Protein, FliD, Is Responsible for Mucin Adhesion (1998)

Mucin-specific adhesion of Pseudomonas aeruginosa plays an important role in the initial colonization of this organism in the airways of cystic fibrosis patients. We report here that the flagellar cap protein, FliD, participates in this adhesion process. A polar chromosomal insertional mutation in the P. aeruginosa fliD gene made this organism nonadhesive to mucin in an in vitro mucin adhesion assay. The adhesive phenotype was restored by providing the fliD gene alone on a multicopy plasmid, suggesting involvement of this gene in mucin adhesion of P. aeruginosa. Further supporting this observation, the in vitro competition experiments demonstrated that purified FliD protein inhibited the mucin adhesion of nonpiliated P. aeruginosa PAK-NP, while the same concentrations of PilA and FlaG proteins of P. aeruginosa were ineffective in this function. The regulation of the fliD gene was studied and was found to be unique in that the transcription of the fliD gene was independent of the flagellar sigma factor sigma28. Consistent with this finding, no sigma28 binding sequence could be identified in the fliD promoter region. The results of the beta-galactosidase assays suggest that the fliD gene in P. aeruginosa is regulated by the newly described transcriptional regulator FleQ and the alternate sigma factor sigma54 (RpoN).
Hierarchically Porous Silica with Ordered Mesostructure from Confinement Self-Assembly in Skeleton Scaffolds (2009)

Hierarchically porous silica materials have been synthesized through a confinement self-assembly approach in the skeletal scaffolds of commercial polyurethane (PU) foams. Macroporous/mesoporous silica materials with a well-ordered two-dimensional (2-D) hexagonal (p6mm) mesostructure have been synthesized in an acidic solution using tetraethoxysilane as a precursor, triblock copolymer Pluronic P123 as a mesostructural template, and PU foams with three-dimensional (3-D) interconnecting strut networks as a macrostructure scaffold. By controlling the volume ratio of the cast silica sol to the PU foam scaffolds, hierarchically porous silica monoliths with various macropore structures can be obtained. The porous silica monoliths can be disassembled into uniform polyhedron-like particles. The porous silica polyhedrons exhibit macropores 100−500 μm in diameter, adjustable uniform mesopores (6.5−9.3 nm in diameter), high surface areas (340−780 m2/g), and large pore volumes (0.48−1.16 cm3/g). The resulting macroporous/mesoporous silica polyhedrons show an excellent adsorption and remove capability of Microcystin-LR in wastewater.
Comparative Value of Prostaglandin E1 and Papaverine in Treatment of Erectile Failure: Double-Blind Crossover Study among Egyptian Patients (1992)

In a double-blind, crossover designation penile intracavernous prostaglandin E1 and papaverine hydrochloride were compared in regard to effectiveness and safety in 52 patients investigated and treated for sexual erectile dysfunction. In evidence of the reliable effectiveness, prostaglandin E1 (20 micrograms/ml.) induced significant positive erectile response in 42 of 52 patients (81%). This rate reached 100% with neurogenic, hyperprolactinemic and/or psychogenic impotence. However, with papaverine hydrochloride (30 mg./ml.) and exclusively in cases of vasculogenic (most probably arteriogenic) impotence, negative erectile response was revealed as absent erection in 6 of 52 patients (11.5%) and nonrigid tumescence in 13 (25%) versus 2 (3.8%) and 8 (15.4%), respectively, with prostaglandin E1. Moreover, with prostaglandin E1 the regional pain was tolerable and transient, and the positive erectile response was not attended by priapism even in patients who formerly had priapism with papaverine hydrochloride. However, presently with prostaglandin E1 the relatively higher cost and shorter expiration period would probably limit its diagnostic and therapeutic use in Egypt, and probably in other developing countries.
Semantic description, discovery and integration for the Internet of Things (2015)

To share and publish the domain knowledge of IoT objects, the development of a semantic IoT model based directory system that manages meta-data and relationships of IoT objects is required. Many researches focus on static relationships between IoT objects. However, because complex relationships between various resources change with time in an IoT environment, an efficient method for updating the meta-data is required. Thus, we propose an IoT-DS as the IoT directory that supports semantic description, discovery, and integration of IoT objects. Firstly, we introduce a semantic IoT component model to establish a shared conceptualization. Secondly, we present general cases of relationships to efficiently interact between IoT-DS and IoT objects. Thirdly, we construct IoT-DS as a Web portal. Finally, we verify in our evaluation study that the query processing time and communication workload imposed by the proposed approach are reduced.
Thermal image processing using neural network (2005)

This paper proposes a thermal image processing system that consists of a small, lightweight noncooled thermal image sensor, a thermal image pre-processor, and a structured neural network. This system can measure precisely the position and posture of occupants from feature data using a low-resolution thermal image captured in the polar coordinate system. This thermal image processing system is expected to develop into an image processing system that will be built in various household electric appliances that utilize the information on the occupants of a room.
Controlled propagation of locally excited vortex dynamics in linear nanomagnet arrays (2010)

The ability to propagate local electromagnetic excitation in a medium with spatially modulated physical properties is important for fundamental science and also for applications in photonic, phononic and magnonic crystals. Here, we present a controlled propagation of locally excited magnetic vortex dynamics through a linear array of nanomagnetic discs by controlling the polarization, chirality and shape of the discs. The control is based upon the magnetostatic interaction between the nanodiscs, mediated by the magnetic side charges generated by the gyrating vortices. The magnitude and sign of the side charges and their separation depend strongly on the magnetic ground states of the vortices, including the core polarization and the chirality. We find that the transmission of peak amplitude and velocity of propagation of the excitation along the array is optimized for identical core polarization and chirality of the nanodiscs with geometric asymmetry. More than seven times increase in the transmitted amplitude is observed in the optimized structure as opposed to the non-optimized structure, which is also found to be robust to defects.
Anti-ulcer drugs in antisecretory doses for "cytoprotection" in arthritic patients? (1986)

Gastric injury and dyspepsia are major side-effects of acetylsalicylic acid (ASA) or most non-steroidal anti-inflammatory drugs (NSADs) which cause either gastric ulcerations or gastroduodenal erosions. There is only a limited number of trials in which the possibility of preventing or treating gastric lesions due to those drugs have been studied in man. This paper reviews trials in which H2-receptor antagonists, pirenzepine and prostaglandins have been investigated. - Pirenzepine given in antisecretory doses seems to improve gastrointestinal symptoms induced by ASA or NSADs. Cimetidine and misoprostol might prevent fecal blood loss. Gastroduodenal lesions might be prevented by pirenzepine, misoprostol and enprostil. It might be possible that cimetidine or ranitidine heal NSAD-induced peptic ulcers better than placebo in arthritic patients who stop the ingestion of NSADs. - All over the results of the cited trials are inconclusive, since the number of patients studied were too small and the design of almost all trials was incomparable. Furthermore, all cited studies do not correspond to Robert's concept of "cytoprotection", since H2-blockers, pirenzepine and prostaglandins have been applied in antisecretory doses in man.
Genome-Wide Identification of WOX Gene Family and Expression Analysis during Rejuvenational Rhizogenesis in Walnut (Juglans regia L.) (2019)

Rejuvenation is an efficient approach used in the cuttings of trees and horticultural crops, to improve their rooting ability, especially in difficult-to-root trees. WOX gene family members are involved in cell-fate transformation through balancing the maintenance and proliferation of the stem cells. However, there are no reports about the WOX gene family in Walnut (Juglans regia L.) and its relationship between rejuvenation and adventitious roots formation (ARF). Here, a genome-wide identification of JrWOX genes and their physical and chemical properties, phylogeny, and expression profiles in different organs and during rejuvenation-induced ARF is reported. The phenotype and histology characteristics of mature and rejuvenated cuttings (Mc and Rc) are also observed. In this study, 12 genes were identified and clustered into three groups based on phylogenetics, special domains, and conserved motifs. The gene structures and conserved motifs were relatively conserved, while the 12 sequences of the JrWOXs domain were diversified. Gene expression in root, stem, leaf, female flower, immature fruit, and zygotic embryo revealed that the expression levels of JrWOX4a, JrWOX4b, JrWOX5, JrWOX11, and JrWOX13 in the root were significantly higher than those of other JrWOXs, while only the expression of JrWOX11 was exclusive to the root organ. Additionally, rejuvenation treatment significantly induced almost all JrWOX genes, except JrWOX4a, JrWOX4b, and JrWOX13 (Rc 0 vs. Mc 0). During the ARF process, the transcripts of JrWOX11 and JrWOX5 were consecutively increased on a significance level; in contrast, the transcription levels of the other JrWOXs decreased or changed insignificantly. The phenotype and histology observation indicate that rejuvenation treatment made the base of the stem expand and reduced the thickness and density of sclerenchyma between the cortex and phloem. This might provide the conditions for the formation of new meristem niches. The results provided insight into the JrWOX genes’ general characteristics and their roles in rejuvenation-induced ARF.
Can the Boat People Assert a Right to Remain in Asylum (1980)

World political reaction to the Southeast Asian refugee crisis has not asserted the refugees' human rights under international law. As a result, most of the refugees lack security from forcible return to the conditions they fled. They would have that security if the world powers act instead to implement non-refoulement, an established moral principle that arguably has attained the status of customary international law.
Computer assisted intervention surgery planning and navigation for percutaneous microwave ablation of lung cancer (2011)

Microwave ablation is a promising option in lung cancer therapy. However, it's rarely used in percutaneous lung cancer therapy compared to liver cancer, because the presence of a large amount of air within the lung creates significant back shadowing artifacts that preclude adequate delineation of anatomic details on sonography. To utilize microwave ablation in malignant lung tumor therapy, we developed a novel percutaneous intervention surgery navigation system (CAINS-I), which capitalizes on using computer assisted technology to help lung cancer patients whose condition are not amenable to surgical resection, sonographic guidance and intraoperative CT surgery. In these surgeries, preoperative CT images with patient respiration state are first acquired, which are then visualized using GPU-accelerated volume rendering. The optimal surgery trajectories are then planned based on 3D thermal field computation and surgery simulation in the surgery planning software. During the surgery, the patient breath is control by a portable volume ventilator system which could limit the movement and displacement of the tumor. Then the microwave probe is punctured into the tumor according to the dynamic respiratory state and the tumor is ablated by microwave energy. After the surgery, postoperative CT are acquired and compared to the preoperative CT, and the surgery is evaluated by compare preoperative and postoperative CT images. The development of this technique represented an advance from the traditional ways for lung cancer therapy and significantly extends the indications of microwave ablation.
Point‐of‐care method for total white cell count: an evaluation of the <i>HemoCue WBC</i> device (2008)

Point-of-care testing (POCT) is becoming an important adjunct to haematology laboratory practice. An important component of the blood count is the total white cell count (WBC). Previously, this required laborious microscopic cell counting, but it can now be performed by means of automation; however, in many under-resourced countries, costly automated counters are only available in very few central hospitals. Moreover, neither method is practical in most POCT situations. The HemoCue WBC has been developed as a simplified alternative method, consisting of a reagent pre-loaded disposable cuvette together with basic image analysis technology. This report describes an assessment of its utility. The WBC of 500 routine blood samples from the hospital were tested in parallel by the HemoCue WBC and by a reference analyser to assess accuracy and utility of the former. The tests included precision, linearity, type of blood sample and anticoagulant and potential interfering substances in blood specimens. In the tests for accuracy, 192 of the 200 showed percentage difference from the NEQAS reference of <10% whilst the remaining eight samples differed by <12%, thus meeting the requirements of Clinical laboratory improvement amendments (CLIA)-88 regulations. Of the samples tested with potential interfering substances only those with >2% normoblasts or reticulocytosis showed significant differences from the reference measurements. The HemoCue WBC is reliable for WBC counts within the analytical range of 0.4-30.0 x 10(9)/l, except in samples where there are significant numbers of normoblasts or reticulocytes. It is simple to use and provides a valuable advance in the facilities available for POCT in haematology.
The accelerator-driven thorium reactor power station (2011)

Aker Solutions conceptually designed the accelerator-driven thorium reactor 600 MWe power station, an accelerator-driven, thorium-fuelled, lead-cooled fast reactor. Project objectives were to demonstrate the technical feasibility of the design to ensure a viable product. Aims were to apply established technology where possible, minimising research and development requirements, develop and protect intellectual property and align with Generation IV strategy. A business case demonstrates economic and market potential to stakeholders, and partners are being pursued to take the project through to successful completion. Thorium is an attractive alternative to uranium fuel, being more abundant and avoiding the need for enrichment. Additionally the accelerator-driven thorium reactor can burn waste actinides generated in uranium-fuelled reactors, providing sustainable energy for future civilisation. Choosing a sub-critical accelerator-driven system provides safe operating margins for the thorium fuel cycle. The proposed reactivity coefficient of 0·995 allows selection of an industrial-scale accelerator with commercial benefits which led to a novel solution for measurement and control of reactivity.
Diamond growth rates (1971)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTDiamond growth ratesR. H. Wentorf Jr.Cite this: J. Phys. Chem. 1971, 75, 12, 1833–1837Publication Date (Print):June 1, 1971Publication History Published online1 May 2002Published inissue 1 June 1971https://pubs.acs.org/doi/10.1021/j100681a013https://doi.org/10.1021/j100681a013research-articleACS PublicationsRequest reuse permissionsArticle Views961Altmetric-Citations190LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Factors Affecting IL-1-Mediated Collagen Metabolism By Fibroblasts and the Pathogenesis of Periodontal Disease: A Review of the Literature (1997)

Fibroblasts have been studied extensively for their contribution to connective tissue destruction in diseases where the metabolism of extracellular matrix components plays an essential part in their pathogenesis. A considerable dissolution, especially of collagen fibrils, is a well-known characteristic of the periodontal ligament and the gingival connective tissue in microbial-induced periodontal disease. Fibroblasts, responsible for the assembly of the extracellular matrix, are capable of responding directly to oral microbial challenges or indirectly, following activation of the host immune response, and can alter the composition of connective tissue in several ways: synthesis of inflammatory mediators, their receptors and antagonists; fibroblast proliferation; collagen synthesis; phagocytosis of collagen fibrils; and synthesis of proteolytic enzymes, including matrix metalloproteinases and their corresponding inhibitors. The contributions of these cellular fibroblastic properties to the pathogenesis of periodontal disease are reviewed in the context of the cytokine, interleukin-1, as the inflammatory regulator.
All-optical, ultra-wideband microwave I/Q mixer and image-reject frequency down-converter (2017)

An all-optical and ultra-wideband microwave in-phase/quadrature (I/Q) mixer, based on a dual-parallel Mach-Zehnder modulator and a wavelength division multiplexer, is proposed. Due to the simultaneous frequency down-conversion and 360-deg tunable phase shifting in the optical domain, the proposed I/Q mixer has the advantages of high conversion gain and excellent quadrature phase balance (<±1.3 deg⁡) with a wide operating frequency from 10 to 40 GHz. Assisted by an analog or digital intermediate-frequency quadrature coupler, an image-reject frequency down-converter is then implemented, with an image rejection exceeding 50 dB over the working band.
Income prediction via support vector machine (2005)

Principal component analysis and support vector machine methods are employed to generate and evaluate income prediction data based on the Current Population Survey provided by the U.S. Census Bureau. A detailed statistical study targeted for relevant feature selection is found to increase efficiency and even improve classification accuracy. A systematic study is performed on the influence of this statistical narrowing on the grid parameter search, training time, accuracy, and number of support vectors. Accuracy values as high as 84%, when compared against a test population, are obtained with a reduced set of parameters while the computational time is reduced by 60%. Tailoring computational methods around specific real data sets is critical in designing powerful algorithms.
Copula based prediction models: an application to an aortic regurgitation study (2007)

Copula-based prediction modeling is demonstrated to be an appropriate alternative to the conventional correlation-based prediction modeling since the correlation-based prediction models are not appropriate to model the dependence in populations with asymmetrical tails. Proposed copula-based prediction model has been validated using the independent bootstrap samples.
OMA DM‐based remote software fault management for mobile devices (2009)

Abstract Mobile devices (e.g. mobile handsets or PDAs) have gained much functionality and intelligence with the growth of mobile network technologies and the increased use of mobile services. As a consequence, mobile devices have become more complex and many related problems have occurred. Specifically, sudden rebooting and freezing problems caused by software faults decrease the availability of the mobile device and cause inconvenience to end‐users. To solve such problems, academia and industry have focused on Open Mobile Alliance (OMA) Device Management (DM); this method is the international de facto standard for mobile device management. In this paper, we propose a software fault management method to remotely determine and correct problems of mobile devices based on OMA DM. We present a definition of management objects and a method to collect them from mobile devices using the OMA DM protocol. We also present a method for debugging and correcting software faults using the collected information. Finally, we present a prototype implementation and performance evaluation to validate our proposed method. Results of the performance evaluation show that our proposed method is efficient and scalable in regard to network traffic overhead and response time. Copyright © 2009 John Wiley & Sons, Ltd.
A Modular System Oriented to the Design of Versatile Knowledge Bases for Chatbots (2012)

The paper illustrates a system that implements a framework, which is oriented to the development of a modular knowledge base for a conversational agent. This solution improves the flexibility of intelligent conversational agents in managing conversations. The modularity of the system grants a concurrent and synergic use of different knowledge representation techniques. According to this choice, it is possible to use the most adequate methodology for managing a conversation for a specific domain, taking into account particular features of the dialogue or the user behavior. We illustrate the implementation of a proof-of-concept prototype: a set of modules exploiting different knowledge representation methodologies and capable of managing different conversation features has been developed. Each module is automatically triggered through a component, named corpus callosum, that selects in real time the most adequate chatbot knowledge module to activate.
The ommaya reservoir.Newly recognized complications and recommendations for insertion and use (1978)

Two of 27 patients treated with intraventricular chemotherapy via an Ommaya reservoir developed unusual life-threatening complications attributable to the reservoir. In one patient treated for meningeal Burkitt's lymphoma, the cause of death was a large mass of tumor cells growing around the cannula. Also the tip of the cannula was found in the contralateral cerebral peduncle. In the other patient, the tip of the cannula apparently perforated the ventricular wall postoperatively and migrated into the contralateral thalamus. In both cases evidence for methotrexate-associated leukoencephalopathy was present at autopsy. Based on the experience with these two patients, we offer specific recommendations for reservoir insertion and use.