gebhart/patrepeval huggingface dataset:
Poster: Discovering Code Dependencies by Harnessing Developer's Activity (2015)

Monitoring software developer's interactions in an integrated development environment is sought for revealing new information about developers and developed software. In this paper we present an approach for identifying potential source code dependencies solely from interaction data. We identify three kinds of potential dependencies and additionally assign them to developer's activity as well, to reveal detailed task-related connections in the source code. Interaction data as a source allow us to identify these candidates for dependencies even for dynamically typed programming languages, or across multiple languages in the source code. After first evaluations and positive results we continue with collecting data in professional environment of Web developers, and evaluating our approach.
Mass spectrometry in grape and wine chemistry. Part I: Polyphenols (2003)

Mass spectrometry, had and still has, a very important role for research and quality control in the viticulture and enology field, and its analytical power is relevant for structural studies on aroma and polyphenolic compounds. Polyphenols are responsible for the taste and color of wine, and confer astringency and structure to the beverage. The knowledge of the anthocyanic structure is very important to predict the aging attitude of wine, and to attempt to resolve problems about color stability. Moreover, polyphenols are the main compounds related to the benefits of wine consumption in the diet, because of their properties in the treatment of circulatory disorders such as capillary fragility, peripheral chronic venous insufficiency, and microangiopathy of the retina. Liquid Chromatography-Mass Spectrometry (LC-MS) techniques are nowadays the best analytical approach to study polyphenols in grape extracts and wine, and are the most effective tool in the study of the structure of anthocyanins. The MS/MS approach is a very powerful tool that permits anthocyanin aglycone and sugar moiety characterization. LC-MS allows the characterization of complex structures of grape polyphenols, such as procyanidins, proanthocyanidins, prodelphinidins, and tannins, and provides experimental evidence for structures that were previously only hypothesized. The matrix-assisted-laser-desorption-ionization-time-of-flight (MALDI-TOF) technique is suitable to determine the presence of molecules of higher molecular weight with high accuracy, and it has been applied with success to study procyanidin oligomers up to heptamers in the reflectron mode, and up to nonamers in the linear mode. The levels of resveratrol in wine, an important polyphenol well-known for its beneficial effects, have been determined by SPME and LC-MS, and the former approach led to the best results in terms of sensitivity.
Substrate Composition and the Effect of ε-Aminocaproic Acid on Tissue Plasminogen Activator and Urokinase-induced Fibrinolysis (1974)

Summary The influence of variations in substrate composition on the biphasic pattern of inhibition by e-aminocaproic acid (EACA) of urokinase-induced fibrinolysis, first observed on bovine plasminogen-rich fibrin, was studied using a fibrin clot lysis time assay. Different species of fibrinogen and plasminogen or plasmin were used. Preparations of different degrees of purification were compared at varying concentrations. The behavior of urokinase was compared with that of a porcine tissue plasminogen activator. Variations in the conditions of the assay greatly influenced the results. The concentration of fibrinogen had a particularly marked influence. At increased fibrinogen concentrations the biphasic response of urokinase was enhanced and a weak biphasic effect was also produced by the tissue activator which usually yields a uniformly increasing inhibition curve. The phase of fibrinolysis enhancement produced by urokinase with genuine plasminogen substrates occurs at substrate concentrations and EACA levels present in patients treated with EACA. The observed variations may explain discordant findings reported by various investigators.
Utilisation of Substrates During Tethered Flight with and without Lift Generation in the African Fruit Beetle <i>Pachnoda Sinuata</i> (Cetoniinae) (1998)

We have investigated the pattern of metabolic changes during tethered flight with and without lift generation in the African fruit beetle Pachnoda sinuata. Two distinct metabolic phases occur during lift-generating flight. The first phase is characterised by a high rate of oxygen consumption and a rapid change in proline and alanine levels in the haemolymph and flight muscles and in glycogen level in the flight muscles. Carbohydrates are released from the fat body into the haemolymph. These carbohydrates are oxidised during the second phase. Changes in proline and alanine levels in the haemolymph and flight muscles and in glycogen level in the flight muscles are minor during the second phase and the rate of oxygen consumption is reduced. During lift-generating flight, metabolic changes are rapid. Proline concentrations in the haemolymph and flight muscles fall dramatically during the first 30 s of flight, while alanine concentrations rise concomitantly. While haemolymph concentrations of proline and alanine remain virtually unchanged thereafter, further changes in the levels of these amino acids occur in the flight muscles during 5 min of flight. The initial levels of the two amino acids in the flight muscles are re-established over 1 h of rest following a 5 min flight, while this process takes longer in the haemolymph. The concentration of haemolymph carbohydrates increases during the first 30 s of flight and declines thereafter during 5 min of flight. The pre-flight levels are restored after 1 h of subsequent rest. The stores of glycogen in the flight muscles are rapidly diminished during the first 10 s of flight and decrease at a lower rate during further flight lasting up to 5 min. A subsequent 1 h of rest is sufficient almost to restore pre-flight levels. Haemolymph lipid levels are slightly but significantly increased during 11 min of flight and after 1 h of subsequent rest. During flight without lift production, the metabolic changes are considerably slower and beetles fly approximately seven times longer than during lift-generating flight. Resting basalar (BM), dorso-ventral (DVM) and dorso-longitudinal (DLM) flight muscles show no differences in levels of proline, alanine and glycogen. After different periods of flight, during which lift and wing loading were minimised, the DVM was found to have the highest level of proline after 5 min of flight. Levels of alanine in the DVM were lower than in the DLM. There was no evidence to suggest that different flight muscles are specialised for either proline or carbohydrate utilisation. Proline and carbohydrates participate equally in supplying energy to the flight muscles during lift-generating flight. The contribution to the energy supply by the flight muscles is 54 %, while that of the haemolymph is 46 %.
The Langevin Hull: Constant Pressure and Temperature Dynamics for Nonperiodic Systems (2011)

We have developed a new isobaric-isothermal (NPT) algorithm which applies an external pressure to the facets comprising the convex hull surrounding the system. A Langevin thermostat is also applied to the facets to mimic contact with an external heat bath. This new method, the "Langevin Hull", can handle heterogeneous mixtures of materials with different compressibilities. These systems are problematic for traditional affine transform methods. The Langevin Hull does not suffer from the edge effects of boundary potential methods, and allows realistic treatment of both external pressure and thermal conductivity due to the presence of an implicit solvent. We apply this method to several different systems including bare metal nanoparticles, nanoparticles in an explicit solvent, as well as clusters of liquid water. The predicted mechanical properties of these systems are in good agreement with experimental data and previous simulation work.
Calcipotriene/betamethasone in the treatment of psoriasis: a review article (2009)

Plaque-type psoriasis is a chronic and immune-mediated skin disease affecting approximately 1-3% of the Caucasian population. Most cases are of mild or moderate severity and benefit from local treatment that represents the mainstay therapy. Topical corticosteroids and vitamin D(3) analogues remain the option of choice. Optimization of these treatments is made by the combination of calcipotriene and betamethasone dipropionate. This formulation combines the keratinocyte differentiation and antiproliferative action of the vitamin D(3) analogues with the anti-inflammatory effect of steroids enhancing effectiveness while reducing the side-effect profile of the single topical agent. In this article, we highlight the advantages of the association of calcipotriene and betamethasone in the treatment of localized plaque-type, scalp and nail psoriasis.
Joint cartilage degradation : basic and clinical aspects (1993)

The structure and function of articular cartilage matrices, C. Anthony Poole heterogeneity of articular chondrocytes and cartilage matrix, Margaret B. Aydelotte and Klaus E. Kuettner growth plate structure and function, Ernst B. Hunziker extracellular matrix of cartilage - collagen, Richard Mayne and Randolph G. Brewton extracellular matrix of cartilage - proteoglycans, Peter J. Neame extracellular matrix of cartilage - glycoproteins, Rose S. Fife and Kenneth D. Brandth role of endogenous proteinases in the degradation of cartilage matrix, Hideaki Nagase and J. Frederick Woessner Jr role of physical and mechanical agents in degrading the matrix, C.H. Evans and T.D. Brown role of crystal deposition in matrix degradation, Herman S. Cheung and Lawrence M. Ryan methods for evaluating mechanisms of cartilage breakdown, A. Robin Poole et al articular cartilage organ cultures in vitro models of matrix hemeostasis, resorption or repair, Teresa I. Morales degradation of articular cartilage in culture - regulatory factors, Mary B. Goldring animal models of osteoarthritis, Nancy Burton-Wurster et al cartilage degradation in animal models of inflammatory joint disease, Robert A. Greenwald pathological cartilage degradation in human arthritides , Robert A. Reife et al immune responses to cartilage proteoglycans in inflammatory animal models and human diseases, Tibor T. Gland et al pharmacological control of cartilage degradation in osteoarthritis, Gene Di Pasquale modulation of cartilage degradation in arthritic diseases by therapeutic agents, Jean-Pierre Pelletier et al prospects for medical intervention in cartilage repair, David Hamerman.
The Unity of «Something Out There» (1990)

Link Viktor. The Unity of «Something Out There». In: Journal of the Short Story in English / Les Cahiers de la Nouvelle, n°15, 1990. A Special Nadine Gordimer Issue. pp. 31-40.
A NOTE ON SENSE-DATA AND DEPTH PERCEPTION (1971)

A NOTE ON SENSE-DATA AND DEPTH PERCEPTION Get access ROBERT G. MEYERS ROBERT G. MEYERS State University of New YorkAlbany Search for other works by this author on: Oxford Academic Google Scholar Mind, Volume LXXX, Issue 319, July 1971, Pages 437–440, https://doi.org/10.1093/mind/LXXX.319.437 Published: 01 July 1971
Analyzing Software Artifacts through Singular Value Decomposition to Guide Development Decisions (2007)

During development, programming teams will produce numerous types of software development artifacts. A software development artifact is an intermediate or final product that is the result or by-product of software development. Hidden relationships and structures within a software system can be illuminated through singular value decomposition using software development artifacts, and these relationships can be leveraged to help guide software development questions regarding the interactions among software files. The goal of this research is to build and investigate a framework called Software Development Artifact Analysis (SDAA) that uses software development artifacts to illuminate underlying relationships within a system. SDAA provides guidelines for selecting and gathering software development artifacts, discovering relationships, and then leveraging the insights gained through the analysis of those relationships. We use singular value decomposition (SVD) to generate the relationships from a matrix of software development artifact metrics. In this research, we use SDAA to create three SVD-based software development analysis techniques: an impact analysis technique, a regression test prioritization technique,
5-Aminoisoquinolinone, a novel inhibitor of poly(adenosine disphosphate-ribose) polymerase, reduces microvascular liver injury but not mortality rate after hepatic ischemia-reperfusion* (2004)

PARP inhibition with 5-AIQ during hepatic ischemia-reperfusion attenuates microvascular injury and reduces the extent of necrotic/apoptotic cell damage but does not protect from oxidative injury and does not improve postoperative survival rate.
Investigation on adaptive wing structure based on shape memory polymer composite hinge (2007)

This paper describes the design and investigation of the SMP composite hinge and the morphing wing structure. The SMP composite hinge was based on SMP and carbon fiber fabric. The twisting recoverability of it was investigated by heating and then cooling repeatedly above and below the Tg. The twisting recoverability characterized by the twisting angle. Results show that the SMP composite hinge have good shape recoverability, Recovery time has a great influence on the twisting recoverability. The twisting recovery ratio became large with the increment of recovery time. The morphing wing can changes shape for different tasks. For the advantages of great recovery force and stable performances, we adopt SMP composite hinge as actuator to apply into the structure of the wing which can realize draw back wings to change sweep angle according to the speed and other requirements of military airplanes. Finally, a series of simulations and experiments are performed to investigate the deformations of morphing wings have been performed successfully. It can be seen that the sweep angle change became large with the increment of initial angle. The area reduction became large with the increment of initial angle, but after 75° the area reduction became smaller and smaller. The deformations of the triangle wing became large with the increment of temperature. The area and the sweep angle of wings can be controlled by adjusting the stimulate temperature and the initial twisting angle of shape memory polymer composite hinge.
Global Perspectives on Peer Sex Education for College Students (2013)

According to the World Health Organization, sexually transmitted diseases and infections continue to be a public health problem across the globe, with most infected persons being between the ages of 15 and 49. A large percentage of those affected by AIDS are 15-24 year olds, an age group which includes college students. Peer sex education is being espoused by non-governmental organizations and administrators as a viable solution to this problem. Peer education strategies and approaches to evaluation differ across programs. Some programs report increased efficacy for educators and trainees while other programs report increases in knowledge and changes in attitudes. Perceptions of peer education and resulting benefits vary based on cultural perspectives. Developers of peer education programs need to critically deconstruct current models and customize programs for particular settings, as demonstrated in several programs. Further research is needed on the effects of peer education on the educator and cultural implications.
Expression of plasminogen activator inhibitors 1 and 2 in lung cancer and their role in tumor progression. (1999)

The plasminogen activator cascade initiated by urokinase type plasminogen activator (u-PA) is involved in extracellular matrix degradation during the tumor invasion process. The plasminogen activator inhibitors 1 (PAI-1) and 2 (PAI-2) are two specific inhibitors of u-PA. We hypothesized that the balance between u-PA and its two inhibitors could be disrupted to favor plasminogen activation during lung cancer progression. Using immunohistochemistry, we analyzed the pattern of expression of u-PA, PAI-1, and PAI-2 in non-small cell lung carcinomas (NSCLC) and neuroendocrine (NE) lung tumors. u-PA and PAI-1 were both detected in stromal fibroblasts and in tumor cells. In 84 NSCLCs, their epithelial expression was strongly correlated and linked to the presence of node metastasis (P = 0.008), whereas their coexpression in fibroblasts was associated with larger tumor size (P = 0.04) and advanced stages (P = 0.009). In 72 NE tumors, u-PA and PAI-1 were more frequently expressed in fibroblasts in high-grade NE tumors (SCLC and large cell NE tumors) than in low- and intermediate-grade tumors (typical and atypical carcinoids). Comparison of in situ hybridization and immunohistochemistry in 14 cases showed that PAI-1 was consistently expressed by stromal fibroblasts, although the protein was also localized in tumor cells. In contrast, the expression of PAI-2 was restricted to fibroblasts and correlated with the absence of nodal involvement (P = 0.005). Considering NE tumors, the frequency of PAI-2 expression decreased along the NE spectrum from typical carcinoids to SCLCs. These data suggest that PAI-lacts in synergy with u-PA to favor tumor invasion process and connotes aggressivity, in contrast with PAI-2, which may block u-PA-mediated proteolysis and is inversely correlated with tumor progression.
Toxicity and drug interactions of levamisole. (1980)

Clinical signs and lesions of levamisole toxicosis include: nausea, vomiting, increased salivation, frequent urination and defecation, colic, dizziness, headache, muscle tremors, ataxia, anxiety, hyperesthesia with irritability, clonic convulsions, depression, rapid respiration, dyspnea, prostration, collapse, hemorrhages in the subepicardium and thalamus, enteritis, hepatic degeneration and necrosis, and splenic congestion. Most of these signs and lesions are similar to those observed in nicotine poisoning. Levamisole causes vasopressor and panting effects which are blocked by ganglionic blocking agents hexamethonium and mecamylamine but are not blocked by atropine. The vasopressor effect of levamisole is blocked by alpha-adrenergic antagonists phentolamine and dibenamine; however, the respiratory effect of levamisole is not affected by these alpha-adrenergic antagonists. Repeated IV injections of levamisole cause a tachyphylactic response. With levamisole-induced tachyphylaxis, the effects of other ganglionic stimulants dimethylpiperazinium and nicotine are also abolished. Levamisole causes an electroencephalographic arousal which is antagonized by atropine sulfate and mecamylamine. There is also a structural similarity of levamisole to nicotine. These studies suggest that levamisole is a nicotine-like compound. Possible treatment of levamisole poisoning is discussed. Drug interactions of levamisole with organophosphates and anthelmintics, eg, pyrantel, methyridine, and diethylcarbamazine, are also discussed.
Loop Overhead Reduction Techniques for Coarse Grained Reconfigurable Architectures (2017)

Due to their flexibility and high performance, Coarse Grained Reconfigurable Array (CGRA) are a topic of increasing research interest. However, CGRAs also have the potential to achieve very high energy efficiency in comparison to other reconfigurable architectures when hardware optimizations are applied. Some of these optimizations are common for more traditional processors but can also lead to large efficiency gains for reconfigurable architectures. This paper investigates three hardware based loop optimization techniques that can significantly improve the energy efficiency of CGRAs. The three techniques are evaluated on processing kernels from the image processing domain as well as an industrial computer vision application. Energy consumption and area estimates are obtained using a CGRA synthesized with a commercial 40nm library. For the three applied techniques (zero-overhead loop accelerator, single-cycle loop support, and loop buffers) the simulation results show overall energy gains of 6.8% for zero-overhead loop support, 13.2% for ZOLA combined with single-cycle loop support and 18.3% for a combination of all optimizations.
Macrophage migration inhibitory factor: a potential therapeutic target for rheumatoid arthritis (2016)

Macrophage migration inhibitory factor (MIF) is originally identified in the culture medium of activated T lymphocytes as a soluble factor that inhibits the random migration of macrophages. MIF is now recognized as a multipotent cytokine involved in the regulation of immune and inf lammatory responses. In rheumatoid arthritis (RA), MIF promotes inf lammatory responses by inducing proinflammatory cytokines and tissue-degrading molecules, promoting the proliferation and survival of synovial fibroblasts, stimulating neutrophil chemotaxis, and regulating angiogenesis and osteoclast differentiation. Expression of MIF in synovial tissue and synovial fluid levels of MIF are elevated in RA patients. Specifically, MIF levels correlate with RA disease activity and high levels are associated with bone erosion. In animal models of RA, the genetic and therapeutic inhibition of MIF has been shown to control inflammation and bone destruction. Based on the role of MIF in RA pathogenesis, small molecular inhibitors targeting it or its receptor pathways could provide a new therapeutic option for RA patients.
VELOCITY ANALYSIS OF M13 BY MAXIMUM LIKELIHOOD METHOD (1992)

We present new approach to analysis of velocity data of globular clusters. Maximum likelihood method is applied to get model parameters such as central potential, anisotropy radius, and total mass fractions in each mass class. This method can avoid problems in conventional binning method of chi-square. We utilize three velocity components, one from line of sight radial velocity and two from proper motion data. In our simplified scheme we adopt 3 mass-component model with unseen high mass stars, intermediate visible stars, and low mass dark remnants. Likelihood values are obtained for 124 stars in M13 for various model parameters. Our preferred model shows central potential of and anisotropy radius with 7 core radius. And it suggests non-negligible amount of unseen high mass stars and considerable amount of dark remnants in M13.
The technical reviews of Ligeti Piano Etude No.4 Fanfares (2015)

Ligeti’s etude Fanfares extends the technical skills demanded of the modern pianist and many incorporate completely new techniques. This etude, which was composed around 1985 consists of some of the most technically demanding issues composed for the piano in the last decades of the 20th century. Through the study of this work the pianist is pushed in new directions as Ligeti extends the limits of the pianistic borders.

	Key words: Ligeti, Piano Etudes, Piano Performance Techniques, Fanfares, Polyrhythm.
Synthesis and molecular structure of vanadium(III) dithiolate complexes: a new class of alkene polymerization catalysts (1999)

The synthesis and catalytic activity in ethylene polymerization of new vanadium complexes of 2,2′-oxydiethanethiolate [O(CH2CH2S)22–] are described; the complexes [V(µ-DIPP)2{O(CH2CH2S)2}Li(MeCN)2] and [V(DIPP){O(CH2CH2S)2}(py)] [DIPP = (OC6H3Pri2-2,6)–] have been structurally characterized.
[Establishment and initial evaluation of health scale of traditional Chinese medicine]. (2007)

Viewing from some TCM concepts and basic characteristics of health, assimilating the operationalization concerning thinking and procedure of modern scientific research, the pilot form of Health Scale of TCM--initial health scale of TCM (iHSTCM) based upon TCM theory was developed. From November 2002 to January 2003, the domain, facets and items of HSTCM were finally established by analyzing the data from a survey of 652 persons in Guangzhou City using iHSTCM. In conclusion, the HSTCM has its theoretical ratio-nality and is applicable. It could be further applied in TCM clinical practice.