gebhart/patrepeval huggingface dataset:
Characterization of the murine T cell receptor for IgE (Fc <i>epsilon</i> RII). Demonstration of shared and unshared epitopes with the B cell Fc <i>epsilon</i> RII. (1988)

Antigenic relationships between the low affinity Fc epsilon R present on murine B and T lymphocytes were studied. A rat mAb (B3B4) and two polyclonal antisera produced by immunizing with the murine B lymphocyte Fc epsilon RII were examined for their ability to inhibit binding of IgE to murine B or T lymphocytes, using an IgE-specific rosette assay. One polyclonal antiserum (goat-anti-mouse Fc epsilon R) inhibited binding of IgE to both B and T lymphocytes, whereas another polyclonal antiserum (rabbit-anti-mouse Fc epsilon R) and the rat mAb inhibited the binding of IgE to B lymphocytes but did not influence the binding of IgE to T lymphocytes. When lymphocytes were surface labeled with 125I, 49-kDa and 38-kDa IgE-binding proteins were immunoprecipitated from B lymphocyte lysates by B3B4 and from B and T lymphocyte lysates by the goat antiserum. Taken together, these results suggest that the Fc epsilon R present on murine B and T lymphocytes are structurally related receptors that share some, but not all, epitopes.
新形式ガスタービン燃焼器の研究(第4報,鈍頭部冷却法と燃焼器特性) (1977)

通商産業省工業技術院の主宰する大型工業技術研究開発制度に基づいた「航空機用ジェットエンジンの研究開発」に関連して,低公害で,高性能な燃焼器の研究開発を進めている。ここに報告する新形式燃焼器は,燃焼室外に設けたダクト中の気流に燃料を供給し,その気流微粒化作用による混合気形成をはかる,通称「AS形」のものである。本報告では,特に内筒鈍頭部の耐久性を検討する目的で,鈍頭部構造として膜冷却法を採用したセクタ形燃焼器につき,その燃焼器特性に及ぼす影響,冷却の効果,および排気特性などについて実験的研究を行った。この結果,鈍頭部に膜冷却構造を採用しても本形式の効果を十分に発揮させることができ,かつ,耐久性も十分なものにできることが判明した。
ChemInform Abstract: Visible Light‐Driven and Chloroperoxidase‐Catalyzed Oxygenation Reactions. (2010)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Object detection and segmentation on a hierarchical region-based image representation (2010)

In this paper we present a general framework for object detection and segmentation. Using a bottom-up unsupervised merging algorithm, a region-based hierarchy that represents the image at different resolution levels is created. Next, top-down, object class knowledge is used to select and combine regions from the hierarchy, in order to define the exact object shape. We illustrate the usefulness of the approach with four different object classes: sky, caption text, traffic signs and faces.
Validation of pedestrian impactor testing upon hybrid vehicle front end profile (2014)

A large number of pedestrians are killed in traffic accidents each year and majority of these fatalities are caused by head injuries and leading to permanent damage. This paper presents the development of a hybrid vehicle front end profile and its validation against head and leg impactors. The vehicle model is represented by a simple vehicle hybrid front end profile consisting of multi body and finite element segments. Four piecewise vehicle parts validation is performed namely the windshield, cowl, hood and bumper. An adult headform obtained from TNO is used to impact the windshield, cowl and hood using the given conditions to study the head injury. Similarly, the hybrid vehicle profile is made to impact the TNO legform to assess the lower limb injuries. The injury criteria are represented in their various forms and the simulation results were compared with the experimental values. A good correlation was achieved.
Improved <i>A Posteriori</i> Speech Presence Probability Estimation Based on a Likelihood Ratio With Fixed Priors (2008)

In this paper, we present an improved estimator for the speech presence probability at each time-frequency point in the short-time Fourier transform domain. In contrast to existing approaches, this estimator does not rely on an adaptively estimated and thus signal-dependent a priori signal-to-noise ratio estimate. It therefore decouples the estimation of the speech presence probability from the estimation of the clean speech spectral coefficients in a speech enhancement task. Using both a fixed a priori signal-to-noise ratio and a fixed prior probability of speech presence, the proposed a posteriori speech presence probability estimator achieves probabilities close to zero for speech absence and probabilities close to one for speech presence. While state-of-the-art speech presence probability estimators use adaptive prior probabilities and signal-to-noise ratio estimates, we argue that these quantities should reflect true a priori information that shall not depend on the observed signal. We present a detection theoretic framework for determining the fixed a priori signal-to-noise ratio. The proposed estimator is conceptually simple and yields a better tradeoff between speech distortion and noise leakage than state-of-the-art estimators.
Engineering of graphene/epoxy nanocomposites with improved distribution of graphene nanosheets for advanced piezo-resistive mechanical sensing (2016)

Conductive nanostructured composites combining an epoxy and graphene have been explored for application as high-performance piezo-resistive mechanical sensor.
Reactions of B-Norcholesterol (1956)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTReactions of B-NorcholesterolWilliam G. Dauben and Gerhard J. FonkenCite this: J. Am. Chem. Soc. 1956, 78, 18, 4736–4743Publication Date (Print):September 1, 1956Publication History Published online1 May 2002Published inissue 1 September 1956https://pubs.acs.org/doi/10.1021/ja01599a055https://doi.org/10.1021/ja01599a055research-articleACS PublicationsRequest reuse permissionsArticle Views97Altmetric-Citations27LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
ChemInform Abstract: KIJANIMICIN. 1. STRUCTURES OF THE INDIVIDUAL SUGAR COMPONENTS (1981)

Abstract Aus dem Hydrolysat von Kijanimicin in 0.5 Nmethanolischem HCl (25°C) wurden die Didesoxy‐L‐ribopyranoside (I) (neu) und (II) sowie zwei anomere L‐ribo‐Hexofuranoside und O‐β‐D‐Kijanosyl‐(l ‐ 17)‐kijanolid isoliert, dessen Hydrolyse in 5 N HCl bei 65°C die neuen Nitro‐Zucker α‐ und β‐D‐Kijanosid (III) ergab (Strukturzuschreibungen nach den 1 H‐ und 13 C‐NMR‐Spektren, für (III) auch nach den Massenspektren).
The Enhancing Effects of Amastatin, Phosphoramidon and Captopril on the Potency of [Met5]-Enkephal n in Rat Vas Deferens (1986)

The enkephalin-inactivating enzymes in rat vas deferens were studied by using the relatively specific inhibitor of each enzyme. The results showed that the rat vas deferens, like the other three preparations, guinea-pig ileum, mouse vas deferens and striatal membranes of guinea-pig brain, which had been investigated previously, contained three distinct enkephalin-hydrolyzing peptidases. Additionally, the enkephalin-hydrolyzing aminopeptidase, endopeptidase-24.11 and peptidyl dipeptidase A in rat vas deferens were found to be inhibited maximally with 1 microM of amastatin, 1 microM of phosphoramidon and 1 microM of captopril, respectively. In contrast to these three enzymes, both L-tyrosyl-L-tyrosine-sensitive dipeptidyl aminopeptidase and D-phenylalanine-sensitive carboxypeptidase were suggested not to be involved significantly in the inactivation of exogenously given enkephalin in rat vas deferens. The characteristics of the enkephalin-degradative enzymes in rat vas deferens were discussed in terms of their similarities to and differences from those in the other preparations.
Minimally invasive recording of His bundle potentials using a gastro-thoracic electrode system configuration (2002)

An important research initiative has allowed for the first time the basis of the Wellens protocol to be performed with a specially developed hexapolar gastro-oesophageal electrode (GOE) device. However, to maximize this new clinical procedure the addition of non-invasive His bundle potentials (HBP) detection will allow complete electro-physiological studies to be performed without the use of transvenous catheterisation and X-ray screening procedures. Thus, we have investigated a new method of HBP detection by using our GOE device. The novel lead configuration used here was between a high impedance chest electrode pad and the end tip electrode of the GOE device. This lead system configuration was combined with an optimized front-end ECG amplification and filtering, a high-resolution digitization at 16-bit, 4 kHz, and a particular SAECG processing technique. In a clinical trial, in four out of eight patients, successful detection of the HBP was observed. Detected HBP amplitude ranged between 1 and 3 /spl mu/V over a background noise (rms) ranging between 0.1 and 0.5 /spl mu/V as measured in the PR interval.
Interfacial free energy, surface excess, and stability of macroemulsions (1988)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTInterfacial free energy, surface excess, and stability of macroemulsionsEli RuckensteinCite this: Langmuir 1988, 4, 6, 1318–1321Publication Date (Print):November 1, 1988Publication History Published online1 May 2002Published inissue 1 November 1988https://pubs.acs.org/doi/10.1021/la00084a020https://doi.org/10.1021/la00084a020research-articleACS PublicationsRequest reuse permissionsArticle Views237Altmetric-Citations11LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Caspase activity and apoptotic markers in ejaculated human sperm (2002)

The objectives of this study were to determine if human ejaculated sperm exhibit active caspases and if caspase-dependent apoptosis markers are identifiable. Sperm from fertile donors and infertile patients were examined after gradient separation into leukocyte-free fractions of high and low motility. Sperm were evaluated for motion parameters, morphology, caspase activation, and apoptosis markers including phosphatidylserine (PS) translocation (annexin V binding) and DNA fragmentation (TUNEL). Active caspase-3 was detected by immunofluorescent microscopy in a small proportion of sperm in situ, in fractions of high and low motility sperm of patients and donors, but low motility fractions had significantly higher numbers of positive sperm. Immunoblot analysis detected inactive procaspase-3 (32 kDa) in all fractions of low sperm motility from patients and donors, while active caspase-3 (17 kDa) was only detected by immunoblotting in a limited number of low motility fractions from patients and in even fewer fractions from donors. Caspase enzymatic activity, as measured using the fluorogenic substrate DEVD-afc, was higher in patients than in donors in both low and high motility fractions. Annexin V staining and DNA fragmentation were detected in a proportion of sperm, with a higher frequency in the low motility fractions. A significant positive correlation between in-situ active caspase-3 in the sperm midpiece and DNA fragmentation was observed in the low motility fractions of patients, suggesting that caspase-dependent apoptotic mechanisms could originate in the cytoplasmic droplet or within mitochondria and function in the nucleus. These data suggest that in some ejaculated sperm populations, caspases are present and may function to increase PS translocation and DNA fragmentation.
Towards Control of Magnetic Fluids in Patients: Directing Therapeutic Nanoparticles to Disease Locations (2012)

This article describes a range of results, from passive magnet design to optimal feedback control of a distributed ferrofluid. Representing magnetic forces as the gradient of a magnetic energy allowed design and demonstration, in animal experiments, of a simple open-loop two-magnet system to inject nanoparticles into the inner ear. Then a petri-dish test bed was used to develop and test optimal closed-loop manipulation of a single ferrofluid droplet.The demonstrated algorithms exploited the quadratic dependence of the magnetic forces on control inputs while accounting for magnet time delays and spatial discontinuities in the optimal control. All dimensional parameters were reduced to three essential nondimensional numbers, and ferrofluid behavior was mapped across the entire feasible drug delivery parameter space.
On the Discretization of Spatially Continuous Systems with Quadratic and Cubic Nonlinearities. (1998)

Methods for the study of weakly nonlinear continuous(distributed parameter)systems are discussed.Approximate solution procedures treating reduced-order models of systems with quadratic and cubic nonlinearities obtained with the Galerkin procedure are constrasted with direct application of the method of multiple scales to the governing partial-differential equations and boundary conditions.By means of several examples and an experiment, it is shown that low-order reduced models of nonlinear continuous systems can lead to erroneous results.A method for producing reduced-order models that overcome the shortcomings of the Galerkin procedure is discussed.Treatment of these models yields results in agreement with those obtained experimentally and those obtained by directly attacking the continuous system.Convergence of the reduced-order models as the order increases is also discussed.
Analysis of the polycycllic aromatic hydrocarbon content of airborne particulate pollutants in a Søderberg paste plant (1977)

A method of enrichment and separation of polycyclic aromatic hydrocarbons (PAH) in air samples is described. Airborne particulate samples from the work atmosphere of a Soderberg carbon-paste plant were collected on glass fiber and Acropor filters using high volume samplers. The filters were Soxhlet-extracted using cyclohexane and extractable matter was subject to a liquid/liquid separation. The PAH-fraction was concentrated and separated on a gas chromatographic system with the possibility of mass spectrometric identification. More than 40 PAH compounds and some heterocyclic compounds having from 3-6 rings have been separated and identified. Quantitative determinations show that some of the PAH-components are 2-3 decades more abundant than recently reported data from urban air samples. The results are presented as a PAH-profile. It is suggested that the PAH-profile may be a characteristic of the process involved. Furthermore, the profile has a potential use of the profile in evaluating potentially hazardous risk of the PAH's.
Guillain-Barr� syndrome accompanied by central nervous system lupus in a patient with juvenile rheumatoid arthritis (2001)

We describe a 17-year-old female with juvenile rheumatoid arthritis accompanied by Guillain-Barré syndrome (GBS) during the course of central nervous system (CNS) lupus. She initially developed CNS lupus, including headache and convulsion. A high-signal area in a magnetic resonance scan of her brain with T2-weighted images was noted, and her cerebrospinal fluid exhibited increased levels of IgG and interleukin-6. Eighteen days after the onset of CNS lupus, polyneuropathy in the lower extremities developed, and a diagnosis of GBS was made. No obvious preceding infections in the upper respiratory or gastrointestinal systems were noted before the onset of GBS, indicating that GBS might be part of the symptoms of CNS lupus.
Longitudinally Pumped By Several Laser Diode Bars 1-khz Q-switched ND:YAG Laser with Nonlinear Frequency Conversion (1998)

The usage of compact diode-pumped nanosecond pulse length, mJ energy and kHz repetition frequency range QCW lasers seems to be very prospective for such applications as micromachinery, spectroscopy, photolithography, color laser displays, etc. Application areas could be sufficiently extended if the near IR laser output could be efficiently converted into the visible and UV spectral ranges 1 (see also Lambda Physik product data: StarLine laser) Assuming the typical Q-switched Nd:YAG laser optical conversion efficiency (at 1064 nm) of about 20 - 30% (with respect to absorbed pump power at 808 nm) one can estimate the required peak pump power incident to the gam crystal (at 300-μs pulses) being in the range of from tens to hundreds of Watt. The corresponding average pump power should be of the order of tens of Watt (at duty cycle of about 20 - 30%). Meaning thermal loading, this level is permissible for end pump layout, which is preferable from a view point of laser conversion efficiency and beam quality. The required pump power for such a laser can be provided by several high power laser diode bars (LDBs), but there is a problem of a proper beam shaping to provide circular symmetrical and tight focusing of a pump light into laser crystal. One of the ways of laser diode bar combining and shaping was reported earlier 2 . In this paper we describe a QCW Nd.YAG laser of the IR, visible and UV ranges, using the modification of mentioned pump technique. It should be also noted that this technique is especially valuable for lasing at quasi 3-level 946-nm neodymium transition.
Synthesis of N‐Substituted γ‐Methylene γ‐Lactams. (2006)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Safety and Immunogenicity of SARS-CoV-2 mRNA-1273 Vaccine in Older Adults (2020)

In this small study involving older adults, adverse events associated with the mRNA-1273 vaccine were mainly mild or moderate. The 100-μg dose induced higher binding- and neutralizing-antibody titers than the 25-μg dose, which supports the use of the 100-μg dose in a phase 3 vaccine trial. (Funded by the National Institute of Allergy and Infectious Diseases and others; mRNA-1273 Study ClinicalTrials.gov number, NCT04283461.).
Optimised surfacelet transform based approach for video denoising (2016)

Video denoising systems aims at the removal of noise within each frames. Most of the video denoising systems employ spatial filtering, wavelet decomposition or by utilizing the temporal coherence by motion estimation. Unfortunately, these denoising systems distorts edges, lines and curves. The drawbacks of temporal correlation based schemes are that they suffer due to aperture problems in optical flow and lighting variations. Surfacelet transform is a potent tool for the processing of multidimensional data. Video signals can be treated as a type of 3D signal and therefore can be represented using surfacelet transform which preserves the edge information and visual quality. In the proposed system, the advantages of surfacelet transform were consolidated with Artificial Bee Colony optimization technique for threshold optimization. The denoised video sequences delivered extraordinary results in terms of peak signal to noise ratio(PSNR) and structural similarity(SSIM) index.
A High-Throughput VLSI Architecture for Hard and Soft SC-FDMA MIMO Detectors (2015)

This paper introduces a novel low-complexity multiple-input multiple-output (MIMO) detector tailored for single-carrier frequency division-multiple access (SC-FDMA) systems, suitable for efficient hardware implementations. The proposed detector starts with an initial estimate of the transmitted signal based on a minimum mean square error (MMSE) detector. Subsequently, it recognizes less reliable symbols for which more candidates in the constellation are browsed to improve the initial estimate. An efficient high-throughput VLSI architecture is also introduced achieving a superior performance compared to the conventional MMSE detectors with less than 28% added complexity. The performance of the proposed design is close to the existing maximum likelihood post-detection processing (ML-PDP) scheme, while resulting in a significantly lower complexity, i.e., 4.5×10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> and 7×10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">4</sup> times fewer Euclidean distance (ED) calculations in the 16-QAM and 64-QAM schemes, respectively. The proposed design for the 16-QAM scheme is fabricated in a 0.13 μm CMOS technology and fully tested, achieving a 1.332 Gbps throughput, reporting the first fabricated design for SC-FDMA MIMO detectors to-date. A soft version of the proposed architecture is also introduced, which is customized for coded systems.
THE USE OF A NEW APPARATUS FOR THE PROLONGED ADMINISTRATION OF ARTIFICIAL RESPIRATION (1929)

A number of patients have come under our observation who have shown intercostal paralysis and considerable weakness of the diaphragm early in the paralytic stage of anterior poliomyelitis; yet the accessory muscles and the diaphragm have been able to support sufficient respiratory movement to keep the patient alive until, in the course of a few days, the paralyzed intercostal muscles began to improve and the patient went on to almost complete recovery. Although this is not the usual termination of these cases, it occurs often enough to stimulate the desire to give all patients with respiratory paralysis this opportunity to recover normal breathing by maintaining artificial respiration over a period of hours, or even days. <h3>LIMITATIONS OF PRESENT METHODS OF PROLONGING LIFE</h3> The means of prolonging life in these patients are limited to the available methods of applying artificial respiration. Of these, the manual methods are not adapted to prolonged
Thermolyse von Oxazolin‐5‐onen, X. 3‐Imidazoline und Δ<sup>3</sup>‐Tetrahydropyrimidine durch Thermolyse von 3‐Oxazolin‐5‐onen aus <i>N</i>‐Acyldipeptiden (1980)

Abstract Die Thermolyse von 2‐(Acylaminomethyl)‐3‐oxazolin‐5‐onen ( 3a – g ) führt unter Eliminierung von CO 2 zu Nitril‐yliden, welche nach innermolekularer Protonenübertragung zu 3‐Imidazolinen 4a – g cyclisieren. Analog liefert das 2‐(Acylaminoethyl)‐Derivat 3h ein Δ 3 ‐Tetrahydropyrimidin 5h . Die Oxazolinone 3 sind aus N ‐Acyldipeptiden 1 leicht zugänglich. Die Temperaturabhängigkeit der 1 H‐NMR‐Spektren von 4 wird diskutiert.