gebhart/patrepeval huggingface dataset:
The complete nucleotide sequences of cDNA clones coding for human myosin light chains 1 and 3 (1987)

Journal Article The complete nucleotide sequences of cDNA clones coding for human myosin light chains 1 and 3 Get access Ulla Seidel, Ulla Seidel Department of Toxicology, Medical School, University of HamburgGrindelallee 117, 2000 Hamburg 13 Search for other works by this author on: Oxford Academic PubMed Google Scholar Eva Bober, Eva Bober §Institut fur Humangenetik, Universität Hamburg2000 Hamburg, FRG Search for other works by this author on: Oxford Academic PubMed Google Scholar Barbara Winter, Barbara Winter +Department of Biochemistry, National Cancer InstituteBethesda, MD, USA Search for other works by this author on: Oxford Academic PubMed Google Scholar Susan Lenz, Susan Lenz Department of Toxicology, Medical School, University of HamburgGrindelallee 117, 2000 Hamburg 13 Search for other works by this author on: Oxford Academic PubMed Google Scholar Peter Lohse, Peter Lohse Department of Toxicology, Medical School, University of HamburgGrindelallee 117, 2000 Hamburg 13 Search for other works by this author on: Oxford Academic PubMed Google Scholar H.H. Arnold H.H. Arnold * Department of Toxicology, Medical School, University of HamburgGrindelallee 117, 2000 Hamburg 13 * To whom correspondence should be addressed Search for other works by this author on: Oxford Academic PubMed Google Scholar Nucleic Acids Research, Volume 15, Issue 12, 25 June 1987, Page 4989, https://doi.org/10.1093/nar/15.12.4989 Published: 25 June 1987
[A meta-analysis on combined effects of benzene series and noise exposure on hearing]. (2012)

噪声主要对听觉系统有特异的损伤作用,且在我国也开展了大量关于噪声对工人听力影响的流行病学调查研究.在许多工作场所,噪声不是唯一的职业病危害因素,噪声与其他职业病危害因素往往同时存在,其中单独苯系物暴露或与噪声相互作用造成职业性听力损失越来越引起大家的关注,但是,不同研究所得出的结论受时间、地区、研究的样本量等因素的限制,误差较大.因此,本文中我们收集1990至2011年关于苯系物与噪声联合暴露对听力影响的文献进行Meta分析,以探讨苯系物是否可加重噪声对听力的影响,为今后苯系物噪声联合暴露状况下劳动者听力保护研究提供依据。
Recovery from total intravenous anaesthesia. Propofol versus midazolam‐flumazenil (1990)

The aim of this study was to compare recovery assessed with the Newman, deletion af a's and postbox tests after total intravenous anaesthsia for procedures lasting more than 90 min, with either propofol (PPF) or midazolam (MDZ), reversed or not by flumazenil (FMZ). Thirty patients scheduled for peripheral surgery were randomly allocated to 3 groups of 10, receiving by continuous infusion until the end of surgery either PPF (n = 10) or MDZ (n = 20) combined with alfentanil. FMZ was administered thereafter to 10 patients receiving MDZ until they opened their eyes on command or to a maximum dose of 1 mg. Recovery tests were performed 45, 90 and 180 min after the end of anaesthesia. Results were analysed with non-parametric tests. Recovery scores were significantly better in the PPF group at all times, reaching control values at 180 min for the three first tests. FMZ reversal did not improve the scores compared to those resulting from MDZ alone. This study provides further data in favour of PPF as far as rapid and complete recovery is concerned. The efficiency of FMZ is incomplete and only transient when administered in a single dose.
Inline fiber optic power sensor featuring a variable tap ratio based on a tightly focused femtosecond laser inscription (2018)

We propose and demonstrate an inline fiber optic power sensor (IFPS) resorting to an embedded waveguide tap, which is formed to traverse across the cladding and core of a standard single-mode fiber. The tap was produced via a single-step inscription based on the femtosecond laser direct-writing method. A tightly focused pulsed laser beam has been particularly exploited to suppress the elongation along the laser propagation direction, thereby improving the cross-sectional symmetry of the created tap waveguide. The fabricated fiber optic tap has been stably combined with a photodiode via a compact package. The achieved tap ratio could be tuned from 1.0% to 5.9% at the wavelength of 1550 nm by adjusting the applied laser power, while the induced excess loss was kept below 0.6 dB. The proposed IFPS will be highly suitable for real-time power monitoring in a variety of applications, including optical communication networks and systems.
Study of object detection based on Faster R-CNN (2017)

Faster R-CNN (R corresponds to “Region”) which combined the RPN network and the Fast R-CNN network is one of the best ways to object detection of R-CNN series based on deep learning. The proposal obtained by RPN is directly connected to the ROI Pooling layer, which is a framework for CNN to achieve end-to-end object detection. The feasibility of Faster R-CNN implementation of ResNet101 network and PVANET network is discussed based on the implementation of Faster R-CNN in VGG16 network. Different Faster R-CNN models can be obtained by training with deep learning framework of Caffe. A better model can be obtained by comparing the experimental results using mean average precision (mAP) as an evaluation index. Numerical results show that Faster R-CNN trained by PVANET network obtained the highest mAP.
Transient supply clamp with a variable RC time constant (2005)

This paper summarizes several basic supply clamping techniques and presents an innovative transient clamp circuit that makes use of some properties of a variable voltage clamp. This circuit varies its RC time constant dependent upon whether or not the integrated circuit (IC) is mounted on a printed circuit (PC) board. If the IC is mounted the time constant of the transient clamp is set very short so it will not interfere in the normal operation of the device. However, if the IC is free standing the RC time constant is set much longer to ensure the clamp will stay on long enough to discharge the entire ESD pulse should the need arise. This clamp circuit was used as a component in the electrostatic discharge (ESD) protection network for an analog intermediate frequency (IF) limiter IC. Human Body Model (HBM) ESD levels increased from less then 300 volts to greater then 2000 volts due to the addition of this protection network.
Effect of Lactobacillus acidophilus supernatants on body weight and leptin expression in rats (2008)

This study demonstrates that direct administration of LS into rat CNS leads to a decrease in body weight of rats and an increase in the expression of leptin in specific areas of the brain and retroperitoneal adipose tissue.
Design and Synthesis of Reactive Aramid Nanostructures for Advanced Nanocomposites with Tailored Morphology and Properties. (2013)

The higher strength-to-weight ratios of nanocomposites have made them novel materials to replace metals in applications requiring high material performance. Nanofiller-reinforced polymer nanocomposites are formed primarily through dispersing strong and stiff nanoparticles in various polymeric matrices, and much of the recent work on nanocomposite mechanics only focuses on improving the reinforcement phase. The design of high-performance nanocomposites, however, also requires polymeric matrices with superior mechanical properties and versatile techniques to tailor these matrices. Suitable polymeric nanoscale building blocks for advanced composite matrices can be prepared from conventionally strong materials. In this dissertation, a high performance polymer poly-paraphenylene terephtalamide, better known as Kevlar or aramid polymer, is employed as a matrix material in the form of nanoscale building blocks for nanocomposites. The synthesis of reactive aramid nanoscale structures has addressed the limitations in the field of synthetic nanocomposites, which has traditionally relied on a set of polymeric building blocks with low reactivity and of limited variability. Reactive nanoscale aramid structures are created to bond with various moieties to form aramid networks with tailored nanostructures, morphologies, and mechanical properties. Stable dispersions of nanoscale Kevlar fibers were first obtained through deprotonating macroscale, commercial Kevlar yarns. The high-aspect-ratio aramid nanofibers were then functionalized to improve their reactivity for bonding by surface treating with phosphoric acid (PA). The PA hydrolysis treatment resulted in two aramid building block nanostructures: nanofibers or nanosheets, depending on the treatment extent. Thirdly, the reactive aramid nanostructures were used as polymeric building blocks that can form strong interactions with citrate-stabilized gold nanoparticles (AuNPs). The resulting Kevlar/gold nanocomposites have an optimized combination of stiffness, strength and strain to failure owing to the reinforcement effect of the metal particles (i.e. AuNPs) through their bonding with the aramid matrix. A structure-property relationship was obtained to systematically tailor and optimize the mechanical properties of these advanced aramid composites. These results are the first demonstration of the possibility for aramid nanoscale fibers to form versatile nanosized building blocks that can then be conjugated to fabricate composite structures involving materials previously thought to be impossible to use, and thus creating a new generation of nanostructured aramd materials.
The relationship between valence and chills in music: A corpus analysis (2020)

Chills experienced in response to music listening have been linked to both happiness and sadness expressed by music. To investigate these conflicting effects of valence on chills, we conducted a computational analysis on a corpus of 988 tracks previously reported to elicit chills, by comparing them with a control set of tracks matched by artist, duration, and popularity. We analysed track-level audio features obtained with the Spotify Web API across the two sets of tracks, resulting in confirmatory findings that tracks which cause chills were sadder than matched tracks, and exploratory findings that they were also slower, less intense, and more instrumental than matched tracks on average. We also found that the audio characteristics of chills tracks were related to the direction and magnitude of the difference in valence between the two sets of tracks. We discuss these results in light of the current literature on valence and chills in music, provide a new interpretation in terms of personality correlates of musical preference, and review the advantages and limitations of our computational approach.
Security Enhancement for Watermarking Technique Using Content based Image Segmentation (2007)

Devising new methods for watermarking with high robustness capabilities is still a challenging research problem. Most of the already proposed schemes suffer from some drawbacks. These proposed algorithms are robust for some range of attacks, but not most of them. As an example, they can not sustain in front of rotation or cropping. This work is a continuation of our works reported in [1-2]. The paper combines both techniques in [1] and [2] to propose a novel watermarking method for data hiding in media signal operating in the frequency domain using content based image segmentation with security enhancing technique. Such watermarking methods present additional advantages over the published watermarking schemes in terms of detection and recovery from geometric attacks, and with better security characteristics.
Seed Source and Quality Influence Germination in Purple Coneflower [Echinacea purpurea (L.) Moench.] (1994)

Six seed lots of purple coneflower were purchased from four commercial seed sources and evaluated for germination in either light or darkness in combination with two temperature regimes (constant 27C vs. alternating 30C for 8 hours and 20C for 16 hours). Seed lot differences accounted for the majority of variation, with two seed lots exhibiting high (81% to 91%) germination and the remaining seed lots having 39% to 66% germination. There was no effect of light on germination, regardless of the seed lot. However, alternating temperatures improved germination in one of the low-germination seed lots. Seed size and inflorescence position did not affect seed germination. Seed harvested at physiological maturity (maximum seed dry weight), but before drying had occurred, had a higher germination percentage than seeds harvested after desiccation, and they maintained a higher germination percentage even after 1 year in storage.
Robot navigation in dense human crowds: Statistical models and experimental studies of human–robot cooperation (2015)

We consider the problem of navigating a mobile robot through dense human crowds. We begin by exploring a fundamental impediment to classical motion planning algorithms called the “freezing robot problem”: once the environment surpasses a certain level of dynamic complexity, the planner decides that all forward paths are unsafe, and the robot freezes in place (or performs unnecessary maneuvers) to avoid collisions. We argue that this problem can be avoided if the robot anticipates human cooperation, and accordingly we develop interacting Gaussian processes, a prediction density that captures cooperative collision avoidance, and a “multiple goal” extension that models the goal-driven nature of human decision making. We validate this model with an empirical study of robot navigation in dense human crowds (488 runs), specifically testing how cooperation models effect navigation performance. The multiple goal interacting Gaussian processes algorithm performs comparably with human teleoperators in crowd densities nearing 0.8 humans/m 2 , while a state-of-the-art non-cooperative planner exhibits unsafe behavior more than three times as often as the multiple goal extension, and twice as often as the basic interacting Gaussian process approach. Furthermore, a reactive planner based on the widely used dynamic window approach proves insufficient for crowd densities above 0.55 people/m 2 . We also show that our non-cooperative planner or our reactive planner capture the salient characteristics of nearly any dynamic navigation algorithm. Based on these experimental results and theoretical observations, we conclude that a cooperation model is critical for safe and efficient robot navigation in dense human crowds.
A Load-Balancing Routing Considering Power Conservation in Wireless Ad Hoc Networks (2006)

Of existing ad-hoc protocols, on-demand routing protocol is suitable to wireless networks that have frequent mobility of nodes. Besides, when network is stable, data is transmitted after choosing shortest path without any consideration of any particular node's traffic, and then traffic is concentrated on a particular node, which raises the problem of delay of transmission and huge energy consuming. In this paper, load-balancing routing method, which considers power conversation, is suggested. The proposed method improves (complements) the function of router discovery by adding energy factor to the existing DSR (dynamic source routing)
Bringing in the Reader (2001)

Much of the literature concerning participant relationships in academic writing has discussed features that project the stance, identity, or credibility of the writer, rather than examining how writers engage with readers. In contrast, this article focuses on strategies that presuppose the active role of addressees, examining six key ways that writers seek explicitly to establish the presence of their readers in the discourse. Based on an analysis of 240 published research articles from eight disciplines and insider informant interviews, the author examines the dialogic nature of persuasion in research writing through the ways writers (a) address readers directly using inclusive or second person pronouns and interjections and (b) position them with questions, directives, and references to shared knowledge. The analysis underlines the importance of audience engagement in academic argument and provides insights into how the discoursal preferences of disciplinary communities rhetorically construct readers.
Inflammatory Bowel Disease and Smoking (2004)

The relationship between smoking behavior and inflammatory bowel disease (IBD) is complex. While Crohn's disease (CD) is associated with smoking and smoking has detrimental effects on the clinical course of the disease, ulcerative colitis (UC) is largely a disease of nonsmokers and former smokers. Furthermore, cigarette smoking may even result in a beneficial influence on the course of ulcerative colitis. The potential mechanisms involved in this dual relationship include changes in humoral and cellular immunity, cytokine and eicosanoid levels, gut motility, permeability, and blood flow, colonic mucus, and oxygen free radicals. Nicotine is assumed to be the active moiety. The differential therapeutic consequences comprise the cessation of smoking in CD and, so far, clinical trials using nicotine in different forms of application for UC. In this article, we review the relationship between cigarette smoking and IBD, considering epidemiological, pathogenetic, and clinical aspects.
MANDATORY AEI TAGGING (1991)

This article discusses automatic equipment identification (AEI) technology and the aspects to be examined before it is accepted by railroad systems universally. To become universal, means that freight cars must be transponder-tagged and that the tagging must be mandatory, without exception. The Association of American Railroads has AEI standards in place, based on technology developed by Amtech and licensed to a number of other suppliers. Areas looked at include the following: implementation of AEI; cost/benefit analysis; rectifying the previous bad image AEI created; AAR's proposed mandatory tagging; where AEI stands now; and Union Pacific's plan for tagging its entire fleet.
Characterization of the platelet aggregation inducer and inhibitor from Echis carinatus snake venom. (1985)

Echis carinatus venom was separated into twenty fractions by means of ultrafiltration and CM-Sephadex C-50 column chromatography. Fraction II possessed inhibitory activity on the aggregation of washed rabbit platelets and fraction XII possessed the procoagulant and platelet aggregation-inducing activity. Both were further purified by gel filtration on a Sephacryl S-200 column. The purified aggregation inducer was a glycoprotein with procoagulant activity 10-12-times that of the crude venom. It possessed proteinase and amidase but was devoid of esterase activity. The molecular weight was 16 000, and it contained 8.7% of neutral sugar. The isoelectric point was pH 7.6. The purified aggregation inhibitor was a single peptide chain with a molecular weight of 6800 and contained 22.1% of neutral sugar. The isoelectric point was pH 4.8. It was devoid of any enzymatic activity of the crude venom. The IC50 was about 10 micrograms/ml on the thrombin-induced platelet aggregation. The inhibitory activity was fully retained after the treatment of the venom aggregation inhibitor with neuraminidase, but was completely destroyed by sodium metaperiodate. Upon heat treatment at 90 degrees C, the venom aggregation inhibitor was heat stable at pH 5.5 for 4 h, but was completely destroyed after 2 h at pH 8.9 and retained about 50% of its inhibitory activity of the control at pH 7.2 for 4 h. The venom aggregation inhibitor decreased the elasticity of the whole blood clot, and this effect was related to its inhibitory action on platelet aggregation instead of blood coagulation.
Changes in protein and nucleic acid synthesis in rat gastric mucosa after pentagastrin. (1977)

The trophic effects of gastrin on gastrointestinal tissues have been shown to be physiologically important. This study was designed to investigate the sequence of changes in macromolecular synthesis in the rat gastric mucosa following a single dose of pentagastrin. The earliest response was an increase at 1-2 h of poly (A) messenger RNA (mRNA). This increase dropped after 4 h but remained slightly elevated even 12 h after pentagastrin. By 6 h there was a large increase in protein synthesis that lasted until 12 h. Accompanying this rise in protein synthesis was a large increase in ribosomal (rRNA) and transfer RNA (tRNA), which peaked at 12 h. The changes in both fractions of RNA and protein were over by 18 h. No significant increase in secreted protein was noted, but there was a slight, transient decrease at 1 h. Pentagastrin stimulated all forms of RNA, but the largest increase was seen in the rRNA fraction. After multiple doses, parallel increases in rRNA and tRNA were seen. The stimulation of protein synthesis could be abolished by actinomycin D, and was, therefore, RNA dependent.
Functional characteristics of in vivo induced neutrophils after differentiation therapy of acute promyelocytic leukemia with all-trans-retinoic acid (1994)

The authors describe the functional capabilities of in vivo induced neutrophils from a patient with acute promyelocytic leukemia (French-American-British M3v) treated with differentiation therapy using all-trans-retinoic acid (45 mg.m-2.day-1). The induced neutrophils from the leukemic clone appeared in the blood 7 days after therapy. Normal neutrophils, presumably derived from nonclonal normal hematopoiesis, appeared 15 days after the initiation of therapy. The induced neutrophils were separated from normal neutrophils by density gradient centrifugation. Their origin was established by fluorescence in situ hybridization. The induced neutrophils were morphologically atypical but stained for myeloperoxidase (Sudan black B) and AS-D chloroacetate esterase and were negative for alpha-naphthyl butyrate esterase. Induced neutrophils were functionally mature, showing nitroblue tetrazolium reduction in 72% of the cells compared with 84% in the normal neutrophil fraction. Both the rate and total killing of Staphylococcus aureus (American Type Culture Collection Strain 25923) were normal in both neutrophil fractions. Random locomotion was equivalent and within the normal reference range in both fractions; however, using the under-agarose technique, induced neutrophils showed a minor chemotactic defect in response to both n-formyl-methionyl-leucyl-phenylalanine (score 292, normal 338-868) and complement-derived chemotactic factors (score 420, normal 457-1408). At autopsy, induced neutrophils infiltrated necrotic myocardial tissue, suggesting a normal response to inflammatory stimuli.
FASTRAD 3.2: Radiation Shielding Tool with a New Monte Carlo Module (2011)

FASTRAD <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">®</sup> is a complete engineering software developed for 3D radiation shielding analyses. A new Monte Carlo module, including forward and reverse methods, performs particle transport and dosimetry for space environment.
Identifying dispersed epigenomic domains from ChIP-Seq data (2011)

RSEG, including source code and documentation, is freely available at http://smithlab.cmb.usc.edu/histone/rseg/.
PERSPECTIVE: Evolutionary biology and the avoidance of antimicrobial resistance (2009)

Evolutionary biologists have largely left the search for solutions to the drug resistance crisis to biomedical scientists, physicians, veterinarians and public health specialists. We believe this is because the vast majority of professional evolutionary biologists consider the evolutionary science of drug resistance to be conceptually uninteresting. Using malaria as case study, we argue that it is not. We review examples of evolutionary thinking that challenge various fallacies dominating antimalarial therapy, and discuss open problems that need evolutionary insight. These problems are unlikely to be resolved by biomedical scientists ungrounded in evolutionary biology. Involvement by evolutionary biologists in the science of drug resistance requires no intellectual compromises: the problems are as conceptually challenging as they are important.