gebhart/patrepeval huggingface dataset:
GCSR laser frequency drift compensation using optimized current waveform on one single electrode (2005)

In this paper we present a new method to compensate the whole frequency deviation due to thermal drift during wavelength switching for a semiconductor laser based on launching a distorted current pulse just on one of the tuning electrodes of the laser. We experimentally confirm its efficiency compared with the time constant technique.
Pulmonary Function in Obese Persons12 (1958)

The purpose of this paper is to report a study of lung function in extremely obese persons. In 1936, Kerr and Lagen (2) called attention to the fact that some obese persons develop dyspnea, cya- nosis, polycythemia, and cardiac failure. They thought that these signs and symptoms developed because of mechanical interference with ventilation, especially movement of the diaphragm. Sieker, Estes, Kelser and McIntosh (3) reported studies in four obese patients and postulated a cardiorespiratory syndrome peculiar to obese per- sons and characterized by somnolence, Cheyne-Stokes respirations, intermittent cyanosis, and polycythemia. At the same time that Sieker and his associates were working on this problem, Auchincloss, Cook and Renzetti (4) and Weil and Prasad (5) observed a peculiar type of polycy- themia associated with obesity. Most of the in- vestigators previously mentioned have reported additional patients characterized by obesity, hypoxemia, polycythemia and alveolar hypoventilation (6-9), and they have been joined by others (10-18). Burwell, Robin, Whaley and Bickel- mann (12) have given the picturesque name "Pickwickian Syndrome" to this combination of signs and symptoms.
Conditioned Media Obtained from a Human Mastocytosis Cell Strain Induce Mast Cells Expressing Chymase but not Tryptase from Human Progenitors (1997)

Human mast cells (MC) were derived from umbilical cord blood and bone marrow progenitors cultured in the presence of a conditioned medium from a human mastocytosis cell strain and recombinant human kit ligand (rhKL). KL induced MC of predominantly two immunophenotypes, MC(T) and MC(TC). In contrast, the conditioned medium induced MC subtypes MC(TC) and a third subtype, MC(C), positive for chymase but negative for tryptase. This study clearly demonstrates that a third type of MC, MC(C), can be induced in vitro from normal human progenitors.
Comparison between permutation and coarse-grained entropy approaches for the assessment of short-term complexity of heart period variability (2014)

The study compares permutation and coarse-grained entropy approaches for the assessment of short-term complexity of the cardiovascular control from heart period (HP) variability recordings. Approaches were applied to simulations and to HP variability series recorded during complete vagal blockade obtained via administration of a high dose of atropine (AT). Differences between the estimated complexity indexes derived from both simulations and real data indicated that permutation entropy has a larger sensitivity to noise than coarse-grained entropy. We recommend caution in applying permutation entropy in presence of short HP variability series characterized by a low signal-to-noise ratio such as after complete vagal blockade induced by AT.
Analysis of microsatellites by direct blotting electrophoresis and chemiluminescence detection (1995)

We describe a fast and reliable method for the nonradioactive analysis of microsatellites. For three dinucleotide repeats within the cystic fibrosis transmembrane conductance regulator (CFTR) gene, the separation of polymerase chain reaction (PCR) products generated with biotinylated primers on a direct blotting electrophoresis system and subsequent chemiluminescence detection is shown. In direct blotting electrophoresis, the separation of DNA fragments depended linearly on size. The reproducible resolution allowed reliable assignment of allele lengths to a given signal. The nonradioactive detection protocol was advantageous compared to radioactive methods: samples could be analyzed within one day due to the fast signal development by 3-(4-methoxyspiro[1,2-dioxetane-3,2'-(5'- chloro)tricyclo[3.3.1.1.3,7]decan]-4-yl)phenylphosphate disodium salt (CSPD). Variation of exposure times enabled differentiation between major bands and byproducts of comparable intensity that are due to the slippage of the Taq polymerase during PCR amplification.
Evolution of Acetic Acid Bacteria During Fermentation and Storage of Wine (1984)

Acetic acid bacteria were present at all stages of wine making, from the mature grape through vinification to conservation. A succession of Gluconobacter oxydans, Acetobacter pasteurianus, and Acetobacter aceti during the course of these stages was noted. Low levels of A. aceti remained in the wine; they exhibited rapid proliferation on short exposure of the wine to air and caused significant increases in the concentration of acetic acid. Higher temperature of wine storage and higher wine pH favored the development and metabolism of these species.
Cover Requirement and Stability of Horizontally Bent Buried Pipelines (2012)

A method of calculating soil cover requirements for horizontally bent buried pipelines is described. In sequence, the results of a comprehensive three-dimensional finite element analysis are used to develop regression models for two dependent variables: maximum allowed temperature change and minimum overburden height. Other variables considered include the pipe diameter and thickness, the radius and angle of the bend, the internal pressure, the fluid specific weight, and the material used. Relationships among the different variables are determined. Finally, the results are checked with respect to several buckling modes to consider elastic instability conditions.
De quelques problèmes relatifs à l'application en Belgique de l'immunité des agents diplomatiques (1967)

info:eu-repo/semantics/published
Temporary occipital fixation in young children with severe cervical-thoracic spinal deformity (2017)

OBJECTIVE The long-term effects of instrumentation and fusion of the occipital-cervical-thoracic spine on spinal growth in young children are poorly understood. To mitigate the effects of this surgery on the growing pediatric spine, the authors report a novel technique used in 4 children with severe cervical-thoracic instability. These patients underwent instrumentation from the occiput to the upper thoracic region for stabilization, but without bone graft at the craniovertebral junction (CVJ). Subsequent surgery was then performed to remove the occipital instrumentation, thereby allowing further growth and increased motion across the CVJ. METHODS Three very young children (15, 30, and 30 months old) underwent occipital to thoracic posterior segmental instrumentation due to cervical or upper thoracic dislocation, progressive kyphosis, and myelopathy. The fourth child (10 years old) underwent similar instrumentation for progressive cervical-thoracic scoliosis. Bone graft was placed at and distal to C-2 only. After follow-up CT scans demonstrated posterior arthrodesis without unintended fusion from the occiput to C-2, 3 patients underwent removal of the occipital instrumentation. RESULTS Follow-up cervical spine flexion/extension radiographs demonstrated partial restoration of motion at the CVJ. One patient has not had the occipital instrumentation removed yet, because only 4 months have elapsed since her operation. CONCLUSIONS Temporary fixation to the occiput provides increased biomechanical stability for spinal stabilization in young children, without permanently eliminating motion and growth at the CVJ. This technique can be considered in children who require longer instrumentation constructs for temporary stabilization, but who only need fusion in more limited areas where spinal instability exists.
A new sulphur-containing macrocyclic sexadentate ligand: 12,13,26,27-tetrahydrotetrabenzo[e,i,o,s,][1,4,11,14,7,18]-tetrathiadiazacycloeicosine (1968)

L. F. Lindoy and D. H. Busch, Chem. Commun. (London), 1968, 1589 DOI: 10.1039/C19680001589
Effect of mode of filler addition on the dynamic mechanical properties of epoxidized natural rubber‐<i>cis</i>‐1,4‐polybutadiene rubber blend (1993)

Abstract The effect of different modes of filler addition on dynamic mechanical properties of 50/50 blends of epoxidized natural rubber (ENR) and cis ‐1,4‐polybutadiene rubber (BR) has been studied. The present study is confined to the systems that have fillers alone to reduce complexities due to the presence of other compounding ingredients and vulcanization. The effects of both carbon black and silica filler have been investigated. The mode of filler addition was found to have a profound influence on the loss tangent (tan δ) peak height, its spread, and the storage modulus, E′ value. The tendency of the filler to adhere predominantly to one of the phases depends on the mode of filler addition and the processing history rather than the individual component polarity or viscosity. © 1993 John Wiley & Sons, Inc.
NKG2A Inhibits Invariant NKT Cell Activation in Hepatic Injury (2009)

Activation of invariant NKT (iNKT) cells in the liver is generally regarded as the critical step for Con A-induced hepatitis, and the role of NK cell receptors for iNKT cell activation is still controversial. In this study we show that blockade of the NKG2A-mediated inhibitory signal with antagonistic anti-NKG2A/C/E mAb (20d5) aggravated Con A-induced hepatitis in wild-type, Fas ligand (FasL)-mutant gld, and IL-4-deficient mice even with NK cell and CD8 T cell depletion, but not in perforin-, IFN-gamma-, or IFN-gamma- and perforin-deficient mice. Consistently, 20d5 pretreatment augmented serum IFN-gamma levels and perforin-dependent cytotoxicity of liver mononuclear cells following Con A injection, but not their FasL/Fas-dependent cytotoxicity. However, blockade of NKG2A-mediated signals during the cytotoxicity effector phase did not augment cytotoxic activity. Activated iNKT cells promptly disappeared after Con A injection, whereas NK1(-) iNKT cells, which preferentially expressed CD94/NKG2A, predominantly remained in the liver. Pretreatment with 20d5 appeared to facilitate disappearance of iNKT cells, particularly NK1(-) iNKT cells. Moreover, Con A-induced and alpha-galactosylceramide-induced hepatic injury was very severe in CD94/NKG2A-deficient DBA/2J mice compared with CD94/NKG2A-intact DBA/2JJcl mice. Overall, these results indicated that a NKG2A-mediated signal negatively regulates iNKT cell activation and hepatic injury.
Reflective navigation: individual behaviors and group behaviors (2004)

An approach to motion planning among moving obstacles is presented, whereby obstacles are modeled as intelligent decision-making agents. The decision-making processes of the obstacles are assumed to be similar to that of the mobile robot. A probabilistic extension to the velocity obstacle approach is used as a means for navigation and modeling uncertainty about the moving obstacles' decisions.
502. Oxidations of organic compounds by cobaltic salts. Part VI. Kinetic and product studies of the oxidations of some carboxylic acids (1965)

A. A. Clifford and W. A. Waters, J. Chem. Soc., 1965, 2796 DOI: 10.1039/JR9650002796
Treatment of ulcerative colitis with mesalazine, prednisolon and azathioprine in a pregnant patient complicated by a primary cytomegalovirus infection (1998)

European Journal of Gastroenterology & Hepatology: December 1998 - Volume 10 - Issue 12 - p A93
Software and hardware architectures for secure computing systems (2009)

Intrusion detection, which refers to the detection of illegal attempts at accessing and manipulating a computing system, is an essential protection mechanism for any computing platform. Despite its importance, currently deployed intrusion detection systems (IDSs) tend to be conservative, incomplete, or impose too much computational overhead. Moreover, IDSs have limited adaptability and extensibility in the face of ever-increasing attack sophistication. 
This thesis describes a novel approach to the problem of intrusion detection and prevention. The approach is built on the realization that a critical requirement for intrusion detection is the ability to observe an appropriate ensemble of features or behaviors, which is often not available or apparent until after the malicious code has executed. The approach proposed in this thesis leverages the “benefit of hindsight” offered by isolation techniques, such as virtualization, in order to execute a program in isolation, irrespective of its code origin, data destination, and control transfers; thus, capturing the program’s complete behavioral model. This is especially attractive when both benign and compromised executions display very similar behavior, which is an inevitable trend as attacks and attackers become more and more sophisticated. 
The thesis also introduces an extension of the proposed IDS approach in the context of embedded systems. Embedded systems are becoming increasingly complex and are being deployed on physically insecure networks, which exposes them to the same risks facing general-purpose systems. This calls for new approaches and design methodologies that consider security as a primary objective in the embedded system design process. 
In addition to intrusion detection, the thesis explores how to enhance the hardware and software architecture of embedded computing platforms to make them more secure. 
The thesis also presents a technique to augment the software stack of an embedded device with a software implementation of the trusted platform module (TPM), and evaluates the imposed energy and run-time overheads. It shows how to accelerate the TPM functionality through a combination of design (choice of cryptographic algorithms), software, and hardware optimizations. Hardware optimizations are already widely used for embedded systems in various forms, including customized hardware, co-processors, and dedicated processors. Along this line of hardware/software co-design, the thesis also proposes architectures to accelerate robust biometric algorithms on embedded devices. 
In summary, this thesis introduces new intrusion detection techniques for both general-purpose and embedded computing systems. It also contributes to the area of design of secure embedded systems.
Insights on the Facet Specific Adsorption of Amino Acids and Peptides toward Platinum (2013)

Engineering shape-controlled bionanomaterials requires comprehensive understanding of interactions between biomolecules and inorganic surfaces. We explore the origin of facet-selective binding of peptides adsorbed onto Pt(100) and Pt(111) crystallographic planes. Using molecular dynamics simulations, we show that upon adsorption the peptides adopt a predictable conformation. We compute the binding energies of the amino acids constituting two adhesion peptides for Pt, S7, and T7 and demonstrate that peptides' surface recognition behavior that makes them unique among populations originates from differential adsorption of their building blocks. We find that the degree of peptide binding is mainly due to polar amino acids and the molecular architecture of the peptides close to the Pt facets. Our analysis is a first step in the prediction of enhanced affinity between inorganic materials and a peptides, toward the synthesis of novel nanomaterials with programmable shape, structure, and properties.
Amperomitric Titration of Mercury(II) with Tetraphenylarsonium Chloride (1957)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAmperomitric Titration of Mercury(II) with Tetraphenylarsonium ChlorideOscar. Menis, R. G. Ball, and D. L. ManningCite this: Anal. Chem. 1957, 29, 2, 245–248Publication Date (Print):February 1, 1957Publication History Published online1 May 2002Published inissue 1 February 1957https://doi.org/10.1021/ac60122a020RIGHTS & PERMISSIONSArticle Views26Altmetric-Citations5LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (499 KB) Get e-Alerts Get e-Alerts
PRECOCIOUS METAMORPHOSIS AND MOULTING DEFICIENCIES INDUCED BY AN ANTI‐JH COMPOUND, FMEV IN THE FALL WEBWORM, <i>HYPHANTRIA CUNEA</i> (1983)

Fluoromevalonate (FMev, ZR‐3516) known as an inhibitor of JH biosynthesis was topically applied in 0.1 to 50 μg/specimen doses to the 3rd, 4th, and 5th instar caterpillars of Hyphantria cunea Drury. The anti‐JH compound induced 3 main types of specific responses: 1) precocious metamorphosis, 2) inhibition of ecdysis, and 3) prolongation of larval development. Precocious pupation was accompanied by behavioural events typical of normal pupation. Third and 4th instar larvae metamorphosed prematurely mostly with the intervention of an intercalary larval instar. The 5th instar exhibited the highest sensitivity to the anti‐JH agent. Within each larval stage the freshly moulted insects proved to be the most susceptible to FMev. Afterwards, the incidence of morphogenetic reaction gradually decreased with age. In another fraction of Hyphantria larvae not responding with precocious pupation, FMev evoked varying degrees of ecdysial disturbance which always resulted in the death of caterpillars. In most cases the anti‐JH compound inhibited the premature pupal moult, too, and these affected insects died as tanned pharate pupae. A complete or partial “rescue” from the effects of FMev was elicited, if simultaneously or subsequently, a single topical dose of a JH analogue, hydroprene was also administered. M. R. Abo‐Elgar, Monoufia Univ., Shibin El‐Kom, Egypt, on occasion of his 60th birthday. ZUSAMMENFASSUNG Induktion verfrühter Metamorphose und gehemmter Häutung durch FMev, eine Verbindung mit Anti‐Juvenilhormon‐ Wirkung beim amerikanischen weissen Bärenspinner , Hyphantria cunea
Modification of Ni-YSZ Surface with High Carbon Tolerance Using GDC Nanoparticles (2017)

The Ni surface supported by YSZ substrate was modified by GDC nanoparticles of several tens of nanometers in size. The GDC nanoparticles were prepared by pulsed laser deposition (PLD) technique on the network-shaped Ni prepared on YSZ substrate. Carbon deposition experiment was carried out for the samples by exposing to dry 5% CH4-Ar mixture at 800 oC. Carbon deposition was suppressed on the Ni/YSZ surface modified by GDC nanoparticles, whereas severe carbon deposition was observed on Ni without GDC nanoparticles. The modification of Ni surface using GDC nanoparticles is a good approach to suppress the carbon deposition behavior for the Ni/YSZ anode for SOFCs.
Absorption, distribution, metabolism and excretion (ADME) of the ALK inhibitor alectinib: results from an absolute bioavailability and mass balance study in healthy subjects (2016)

1. Alectinib is a highly selective, central nervous system-active small molecule anaplastic lymphoma kinase inhibitor. 2. The absolute bioavailability, metabolism, excretion and pharmacokinetics of alectinib were studied in a two-period single-sequence crossover study. A 50 μg radiolabelled intravenous microdose of alectinib was co-administered with a single 600 mg oral dose of alectinib in the first period, and a single 600 mg/67 μCi oral dose of radiolabelled alectinib was administered in the second period to six healthy male subjects. 3. The absolute bioavailability of alectinib was moderate at 36.9%. Geometric mean clearance was 34.5 L/h, volume of distribution was 475 L and the hepatic extraction ratio was low (0.14). 4. Near-complete recovery of administered radioactivity was achieved within 168 h post-dose (98.2%) with excretion predominantly in faeces (97.8%) and negligible excretion in urine (0.456%). Alectinib and its major active metabolite, M4, were the main components in plasma, accounting for 76% of total plasma radioactivity. In faeces, 84% of dose was excreted as unchanged alectinib with metabolites M4, M1a/b and M6 contributing to 5.8%, 7.2% and 0.2% of dose, respectively. 5. This novel study design characterised the full absorption, distribution, metabolism and excretion properties in each subject, providing insight into alectinib absorption and disposition in humans.
L’école de Fontenay-le-Fleury (Seine-et-Oise) sous l’ancien régime (1714) (1891)

Thénard J. F. L’école de Fontenay-le-Fleury (Seine-et-Oise) sous l’ancien régime (1714). In: La revue pédagogique, tome 18, Janvier-Juin 1891. pp. 543-548.
Insulin-like growth factor I (rhIGF-I) as a therapeutic agent for hyperinsulinemic insulin-resistant diabetes mellitus (1995)

Insulin resistance is one of the major underlying abnormalities in NIDDM, however, its pathophysiologic mechanisms are not well understood. Many clues about the mechanisms of insulin action have come from patients with the most severe forms of insulin resistance, including those with genetic abnormalities in the insulin signal transduction cascade. We used rhIGF-I as a probe to differentiate insulin and IGF-I action and to study the therapeutic potential of IGF in states of insulin resistance. To date, we have studied six subjects with varying phenotypes of severe insulin resistance but without mutations in the insulin receptor itself. All subjects underwent baseline physiologic monitoring to quantitate carbohydrate tolerance, insulin secretion, and insulin action prior to receiving rhIGF-I at 100 micrograms/kg body wt s.c. bid for 1 month with interval testing of glycemic control and insulin sensitivity. None of the six subjects noted significant side effects from the rhIGF-I. Four of the six subjects had overt diabetes during control testing; three of these subjects demonstrated normalization of fasting and postprandial blood glucose concentrations during rhIGF-I administration on no other therapy. In the fourth patient, insulin requirements and fasting hypertriglyceridemia decreased without improvement in glycemic control. The two subjects with normal glucose tolerance (two sisters with congenital lipodystrophy) maintained normal glucose tolerance at dramatically lower insulin levels and had a dramatic reduction in triglyceride levels. The efficacy of IGF-I continued to increase over the duration of the study.(ABSTRACT TRUNCATED AT 250 WORDS)
HISTOCHEMICAL STUDIES ON CUTANEOUS LEIOMYOMATOSIS. II: DEHYDROGENASES, HYDROLASES AND PHOSVHORYLASE. (1964)

Journal Article HISTOCHEMICAL STUDIES ON CUTANEOUS LEIOMYOMATOSIS. II: DEHYDROGENASES, HYDROLASES AND PHOSVHORYLASE. Get access M. NIEMI, M. NIEMI Department of Pathology Search for other works by this author on: Oxford Academic Google Scholar E. LEVONEN, E. LEVONEN Department of Forensic Medicine Search for other works by this author on: Oxford Academic Google Scholar K.K. MUSTAKALLIO K.K. MUSTAKALLIO Department of Dermatology, University of Helsinki, Snellmaninkatu 14, Helsinki, Finland Search for other works by this author on: Oxford Academic Google Scholar British Journal of Dermatology, Volume 76, Issue 7, 1 July 1964, Pages 341–345, https://doi.org/10.1111/j.1365-2133.1964.tb14539.x Published: 01 July 1964