In vitro toxicity indicators (1994)

Contributors. Preface. Perspectives: Cellular and Molecular Pathobiology of Reversible and Irreversible Injury, B.F. Trump and I.K. Berezesky. Molecular Mechanisms of Toxic Cell Death: An Overview, P. Nicotera and S. Orrenius. Membrane Lipid Peroxidation: Cellular Mechanisms and Toxicological Implications, L. Ernster and P. Hochstein. Membrane Integrity and Function: Enzyme Leakage as an Indicator of Cytotoxicity in Cultured Cells, A.A. Welder and D. Acosta. Cellular K+, V. Kefalas and N.H. Stacey. Morphological and Biochemical Investigations on Plasma Membrane Blebbing During Cell Injury, G. Bellomo, F. Mirabelli, M. Vairetti, F. Iosi, and W. Malorni. Morphological Evaluation of Gap Junctional Intercellular Communication, J.E. Klaunig and T.K. Baker. Fluorescence Microscopic Examination of Cytoskeletal Elements, I.-N. Chou, W. Li, and G.B. Zamansky. Energy Coupled Na+ Cotransport, S.M. Ford. Renal Organic Ion Transport, C.E. Groves, H.V. Sheevers, and S.J. McGuinness. Endoplasmic Reticulum Calcium Pump, L. Moore. Energy Metabolism: Measurement of Oxygen Consumption, R.G. Schnellmann. ATP and Other Energetic Parameters as Indicators of Cell Injury, Y. Park, T.Y. Aw, and D.P. Jones. Evaluation of Glucose Metabolism in Vitro: Altered Competence of Intermediary Metabolism as an Index of Hepatotoxicity, M.J. Olson. DNA-Related Indices: Quantitation of DNA by Fluorometry, S.R. Gallagher and Z. Rymaszewski. Techniques for Measuring Cell Proliferation, F. Dolbeare and M. Vanderlaan. Nuclease P1-Enhanced 32P-Postlabeling Assay for Aromatic Carcinogen-DNA Adducts, M.V. Reddy and K. Randerath. Genomic Hypomethylation, V.L. Wilson. DNA Degradation: Double-Strand Breaks, A.H. Wyllie, M.J. Arends, R.M. Hogg, and A. Nunn. Genotypic Mutation Analysis by RFLP/PCR, F. Aguilar and P. Cerutti. Functional Indices: Gluconeogenesis in Liver Cells, R.G. Knowles and C.I. Pogson. Measurement of Protein Synthesis, M.J. Meredith. Measuring Collagen Synthesis, W.J. Lindblad. Measurement of Macrophage Phagocytosis Using a Sheep Red Blood Cell Assay, G.L. Finch. Biochemical Indices: Cell Function Studies Using Fluorescent Ca2+ Indicators, A.P. Thomas. Ca2+-Bioluminescent Indicators, A.B. Borle. Measurement of Receptor-Activated Accumulation of Inositol Phosphates as an Index of Phospholipase C Activity, S.B. Shears. Covalent Binding to Proteins, S.D. Nelson. Glutathione, Oxidized Glutathione, and Mixed Disulfides in Biological Samples, E.P. Gallagher, T.J. Kavanagh, and D.L Eaton. Lipid Peroxidation: Thiobarbituric Acid Assay Reactants, S.D. Aust. Volatile Hydrocarbons, H. Kappus. Electronically Excited State Formation, E. Cadenas, C. Giulivi, F. Ursini, and A. Boveris. Spectrophotometric Detection of Lipid-Conjugated Dienes, E.A. Glende, Jr., and R.O. Recknagel. Quantitation of Conjugated Dienes by a Dieles-Alder Reaction, D.A.G. Mickle. Quantitation of Conjugated Dienes by Second-Derivative UV Spectroscopy, F.P. Corongiu, S. Banni, and B. Lombardi. Specialized Techniques: A Centrifuge Filtration Separation of Cells, and the Measurement of Constituents, D.J. Reed. Flow Cytometry, J.D. Laskin and D.L. Laskin. Single-Cell Microscopic Techniques for Studying Toxic Injury, J.J. Lemasters, A.-L. Nieminen, E. Chacon, J.M. Bond, I. Harper, J.M. Reece, and B. Herman. Measurement of Macrophage and Neutrophil Chemotaxis, D.L. Laskin. Two-Dimensional Electrophoresis as Applied to Problems of in Vitro and in Vivo Toxicology, N.L. Anderson, R. Esquer-Blasco, and N.G. Anderson. Index.