gebhart/patrepeval huggingface dataset:
Role of epitope density in the induction of immunity and tolerance with thymus‐independent antigens. II. Studies with 2,4‐dinitrophenyl conjugates <i>in vivo</i> (1975)

Abstract The immunogenicity and tolerogenicity of 2,4‐dinitrophenyl (DNP) conjugates of levan, type 3 pneumococcal polysaccharide (SIII), dextran B512 and dextran B 1299 with different levels of substitution were assessed in vivo . It was confirmed that, as in vitro , conjugates with low epitope density are solely immunogenic for B μ cells, whereas higher density conjugates are both immunogenic and tolerogenic according to dosage. The maximal anti‐DNP plaque‐forming cell responses attainable varied by 2 log 10 according to the carrier, being greatest with dextrans and least with SIII. The effect of the carrier on immunogenicity was not attributable to B cells responding to it, as concurrent tolerization by either free polysaccharide or the conjugate itself was without effect. Optimal immunization was succeeded by varying degrees of responsiveness (“exhaustion”) which was greatest with the more immunogenic conjugates. In contrast, reduction of tolerizing dose by cyclophosphamide suppression was only a feature of more highly substituted conjugates.
Robust Control of Steam Turbine System Speed Using Improved IMC Tuned PID Controller (2012)

Abstract This papers explains the method of obtaining proportional, integral and derivative (PID) parameters for singe loop control of turbine speed control system by approximating the feedback form of an IMC controller with elimination of higher order terms in the controller form to classical PID form for Robust operation. The IMC has single tuning parameter to adjust the performance and robustness of the controller. The proposed method is the efficient in set-point tracking and disturbance rejection and controlling the overshoot, stability and dynamics of the speed control of turbine. The results obtained in simulated environment implemented in LabVIEW show the improvement in the performance compared to PID tuning using convention techniques like Ziegler-Nicholas (Z-N) rules and tuning technique proposed by Y. Lee et.al.
Active buffering plus compressed migration (2002)

Scientific simulations running on parallel platforms output intermediate data periodically, typically moving the output to a remote machine for visualization. Due to the large data size and slow network, improvements in output and migration performance can significantly reduce simulation turnaround time. In this paper, we propose a novel simulation execution environment that integrates active buffering and compressed migration to hide and reduce the cost of output and migration. Our implementation removes previous shortcomings of active buffering and of compressed migration, and our experiments with real world data sets show that integrating the two techniques brings comparable application-visible I/O performance and much more flexibility compared to compressed migration without active buffering. The performance advantage will increase with slower-to-write file formats such as HDF.
No pasaràn, Album souvenir. (2004)

Ce texte est une retranscription littérale de la narration du film No pasarán, album souvenir de Henri-François Imbert, © Libre cours 2003, dont sont également extraites les images présentées dans ce numéro de Multitudes.
Modeling and Control of Turbocharged SI and DI Engines (2007)

A component based modeling methodology for turbocharged engines is described and applied. Several component models are compiled and reviewed. In addition new models are developed for the compressor efficiency, compressor flow, and turbine flow. Two application examples are finally given where the modeling methodology and the component models have been used. The applications are, firstly, observer design and air/fuel ratio control of SI engines and, secondly, control design of DI engines with VGT and EGR.
The Ethnic Restaurateur (2016)

<JATS1:p>Academic discussions of ethnic food have tended to focus on the attitudes of consumers, rather than the creators and producers. In this ground-breaking new book, Krishnendu Ray reverses this trend by exploring the culinary world from the perspective of the ethnic restaurateur.</JATS1:p> <JATS1:p>Focusing on New York City, he examines the lived experience, work, memories, and aspirations of immigrants working in the food industry. He shows how migrants become established in new places, creating a taste of home and playing a key role in influencing food cultures as a result of transactions between producers, consumers and commentators.</JATS1:p> <JATS1:p>Based on extensive interviews with immigrant restaurateurs and students, chefs and alumni at the Culinary Institute of America, ethnographic observation at immigrant eateries and haute institutional kitchens as well as historical sources such as the US census, newspaper coverage of restaurants, reviews, menus, recipes, and guidebooks, Ray reveals changing tastes in a major American city between the late 19th and through the 20th century.</JATS1:p> <JATS1:p>Written by one of the most outstanding scholars in the field, The Ethnic Restaurateur is an essential read for students and academics in food studies, culinary arts, sociology, urban studies and indeed anyone interested in popular culture and cooking in the United States.</JATS1:p>
FenceBook a Geofencing based Advertisements Application Using Android (2016)

Geo-fencing (geofencing) is a great feature in a software program that uses Global Positioning System (GPS) or radio frequency identification (RFID) to define the geographical boundaries feature. Actually geofence is a virtual barrier. Geofencing is an innovative technology, an online marketplace for proactive contextual services that allows users to easily find interesting services, can easily subscribe to it and to allow providers offer their services for a variety of applications such as electronic toll collection, contextual advertising or tourist information systems, even without additional infrastructure. The main objective of this research was to understand how the use of spatial data can improve advertising performance for customers. Tracking systems and monitoring, based on global navigation services by satellite, and include geofencing function, could also contribute to the exact location of an institution or company and increase sales and business perspective efficiently. Instead of large billboards they can now advertise on smartphones which is economically and accurately tested. Therefore, we have developed a concept for a market that offers geofence, which can be applied by all and increase the use and integration of proactive services based on location in everyday life.
Preoperative imaging of colorectal carcinoma with 111In-labeled anticarcinoembryonic antigen monoclonal antibody. (1986)

Patients with primary, recurrent, or metastatic colorectal adenocarcinoma were given injections of 200 micrograms of anticarcinoembryonic antigen (CEA) monoclonal antibody labeled with 2 mCi of 111In (Indacea). Patients were imaged at 24 and 48 h. Celiotomy was performed on 40 patients between 3 and 17 days post-Indacea injection. Of 16 primary tumors, 11 (69%) were imaged. Of six extrahepatic recurrences, none was imaged. Intrahepatic metastases were visualized as negative images in 10 of 24 (42%) patients. On the basis of the activity in tissue expressed as a percentage of the total radioactive dose per kg injected into the patient (% ID/kg), extrahepatic tumors that were imaged using Indacea had a significant uptake of radiolabel in the tumor [5.99 +/- 0.91% ID/kg (SE)] and in the associated normal mesenteric lymph nodes (12.0 +/- 2.4% ID/kg). The CEA content of these tumors was high (13.3 +/- 4.7 micrograms/g), and, histologically, the CEA was located primarily apically or intraluminally. Intrahepatic tumor imaging correlated only with tumor size. The greatest Indacea uptake was seen in normal liver (22.1 +/- 3.2% ID/kg). Low Indacea uptake was seen in fat (0.21 +/- 0.05% ID/kg) and bowel wall (1.11 +/- 0.17% ID/kg). In conclusion, Indacea imaging of colorectal carcinoma is specific for high concentrations of accessible CEA in CEA-bearing tumors or in lymph nodes draining these tumors. The successful clinical use of monoclonal antibodies for tumor imaging and therapy will require careful selection of patients for a number of antigen-related parameters including antigen content and distribution in tumors. This information will only come from careful correlation between image results and tissue analysis. High uptake by normal liver tissue is the major unresolved problem with labeled antibody imaging.
A low power carry select adder with reduced area (2002)

A carry-select adder can be implemented by using single ripple carry adder and an add-one circuit instead of using dual ripple-carry adders. This paper proposes a new add-one circuit using the first zero finding circuit and multiplexers to reduce the area and power with no speed penalty. For bit length n=64, this new carry-select adder requires 38 percent fewer transistors than the dual ripple-carry carry-select adder and 29 percent fewer transistors than Chang's carry-select adder using single ripple carry adder. This new 64b adder has 3.45 ns delay time at 2.5 V power supply using a 0.25 um CMOS technology.
Leveraging Frequency-Dependent Kernel and DIP-Based Clustering for Robust Speech Activity Detection in Naturalistic Audio Streams (2018)

Speech activity detection (SAD) is front-end in most speech systems, e.g., speaker verification, speech recognition etc. Supervised SAD typically leverages machine learning models trained on annotated data. For applications like zero-resource speech processing and NIST-OpenSAT-2017 public safety communications task, it might not be feasible to collect SAD annotations. SAD is challenging for naturalistic audio streams containing multiple noise-sources simultaneously. We propose a novel frequency-dependent kernel (FDK) based SAD features. FDK provides enhanced spectral decomposition from which several statistical descriptors are derived. FDK statistical descriptors are combined by principal component analysis into one-dimensional FDK-SAD features. We further proposed two decision backends: First, variable model-size Gaussian mixture model (VMGMM); and second, Hartigan dip-based robust feature clustering. While VMGMM is a model-based approach, the DipSAD is nonparametric. We used both backends for comparative evaluations in two phases: first, standalone SAD performance; and second, the effect of SAD on text-dependent speaker verification using RedDots data. The NIST-OpenSAD-2015 and NIST-OpenSAT-2017 corpora are used for standalone SAD evaluations. We establish two Center for Robust Speech Systems (CRSS) corpora namely CRSS-PLTL-II and CRSS long-duration naturalistic noise corpus. The CRSS corpora facilitate standalone SAD evaluations on naturalistic audio streams. We performed comparative studies of the proposed approaches with multiple baselines including SohnSAD, rSAD, semisupervised Gaussian mixture model, and Gammatone spectrogram features.
Two years of Early Start Denver Model reduces cognitive and language impairments in very young children with autism spectrum disorders (2010)

1 Abstracted from: Dawson, G., Rogers, S., Munson, J., Smith, M., Winter, J., Greenson, J., Donaldson, A., & Varley, J. (2010). Randomized, controlled trial of an intervention for toddlers with autism: The Early Start Denver Model. Pediatrics, 125, 17–23. Source of funding and disclosure of interest: The study was supported by a grant from National Institute of Mental Health; Sally Rogers and Geraldine Dawson are authors of Early Start Denver Model for Young Children with Autism, from which they receive royalties. The authors alone are responsible for the content and writing of the paper.
Cooling by Time Reversal of Atomic Matter Waves (2008)

We propose an experimental scheme which allows us to realized approximate time reversal of matter waves for ultracold atoms in the regime of quantum chaos. We show that a significant fraction of the atoms return back to their original state, being at the same time cooled down by several orders of magnitude. We give a theoretical description of this effect supported by extensive numerical simulations. The proposed scheme can be implemented with existing experimental setups.
Randomized comparison of operator radiation exposure during coronary angiography and intervention by radial or femoral approach (2005)

Controversial data have been published on the amount of radiation exposure during radial coronary procedures. We hypothesized that in the current era, high-volume operators with optimal technique would not be exposed to higher radiation doses during radial procedures. A total of 297 patients undergoing cardiac catheterization (195 elective diagnostic coronary angiograms and 102 elective coronary interventions) were prospectively assigned in a random fashion to the radial access (RA) or femoral access (FA). All procedures were performed by the same operator with vast experience in radial procedures and standard measures for radiation protection were used. Operator radiation exposure was measured with an electronic radiation dosimeter attached to the breast pocket of the operator on the outside of the lead apron and estimates of the ambient dose equivalent were derived. For coronary angiograms, fluoroscopy time (2.8 +/- 2.1 vs. 1.7 +/- 1.4 min; P < 0.001) and dose-area product (15.1 +/- 8.4 vs. 13.1 +/- 8.5 Gy x cm(2); P < 0.05) were increased by 18% and 15%, respectively, for RA vs. FA. Operator radiation exposure was 100% higher for the RA compared to the FA (64 +/- 55 vs. 32 +/- 39 microSv; P < 0.001). For coronary interventions, fluoroscopy time (11.4 +/- 8.4 vs. 10.4 +/- 6.8 min; P = NS) and dose-area product (46.3 +/- 28.7 vs. 51.0 +/- 29.4 Gy x cm(2); P = NS) for RA and FA were not statistically different. However, operator radiation exposure was increased by 51% for the RA compared to the FA (166 +/- 188 vs. 110 +/- 115 microSv; P < 0.05). This study demonstrates that the radial approach is burdened with a 100% increase in operator radiation exposure during diagnostic coronary catheterization procedures and a 50% increase during coronary interventions, provided that no special devices for radiation protection are used. Measurements of radiation dose, such as fluoroscopy time and dose-area product, substantially underestimate the disproportionate rise in radiation exposure. Special precautions are warranted to improve radiation protection during invasive coronary procedures via the radial approach.
A Chronology of Thermal Ink-Jet Structures (1996)

Over the past dozen years, thermal inkjet (TIJ) pens have become one of the largest businesses based on micromachining technology. The basic functioning of an inkjet pen is discussed and four generations of mircostructures from the leading manufacturer are examined. Future trends are analyzed including nozzle count and drop volume.
[Antioxidant effect on the growth of Saccharopolyspora erythraea and biosynthesis of erythromycins]. (2005)

Oxidative stress in the mycelium of submerged culture of S. erythraea, an organism producing erythromycins, was observed. The stress could be eliminated by addition of antioxidants, such as butyloxyanisole, alpha-tocopherol, cytochrome C to the culture. In the presence of the antioxidants the mycelium lysis decreased, the level of the decrease being higher in the medium preferably containing carbohydrates vs. the medium mainly containing lipids (soybean oil). The antioxidants had no specific effect on the biosynthesis of erythromycins.
A tale of two markets: employer expectations of information professionals in Australia and the United States of America (2005)

This paper reports the findings of an exploratory study of 395 library job advertisements in Australia and the USA from August to October 2004. To investigate similarities and differences between the two countries' data we conducted a content analysis and co-word analysis of professional job ads from academic, public and special libraries. Interpersonal Skills, Behavioural Characteristics, and responsiveness to a changeable Environment were identified as critical requirements in both countries.
An in vivo assessment of the influence of needle gauges on endodontic irrigation flow rate (2016)

Needle gauge has significant influence on endodontic irrigation flow rate.
Differential Activation of the <i>tcpPH</i> Promoter by AphB Determines Biotype Specificity of Virulence Gene Expression in <i>Vibrio cholerae</i> (2000)

Vibrio cholerae strains of the classical biotype express the genes encoding cholera toxin (CT) and toxin-coregulated pilus (TCP) under a variety of environmental conditions in vitro, whereas El Tor biotype strains express these genes only under specialized culture conditions. We show here that a single base-pair difference at positions -65 and -66 of the classical and El Tor tcpPH promoters, respectively, is responsible for the differential regulation of virulence gene expression in these two disease-causing biotypes. Analysis of tcpP-lacZ fusions in both V. cholerae and Escherichia coli indicated that transcriptional activation of the El Tor tcpPH promoter by the LysR regulator AphB was significantly reduced relative to that of the classical promoter. Reciprocal exchange of the tcpPH promoter between the two biotypes in V. cholerae showed that the ability to activate the transcription of tcpPH is not dependent on the biotype of the strain per se but on the tcpPH promoter itself. Classical and El Tor tcpP-lacZ promoter chimeras in E. coli localized the region responsible for the differential activation of tcpPH by AphB to within 75 bp of the transcriptional start site. Individual base-pair changes within this region showed that the presence of either an A or a G at position -65 or -66 conferred the classical or El Tor, respectively, pattern of tcpPH activation by AphB. Reciprocal exchange of these base pairs between biotypes in V. cholerae switched the biotype-specific pattern of expression of tcpPH as well as the production of CT and TCP in response to environmental stimuli.
Very high cycle fatigue of engineering materials : A literature review (2009)

Many engineering components reach a finite fatigue life well above 109 load cycles. Some examples of such components are found in airplanes, automobiles or high speed trains. For some materials the fatigue failures have lately been found to occur well after 107 load cycles, namely in the Very High Cycle Fatigue (VHCF) range. This finding contradicted the established concept of fatigue limit for these materials, which postulates that having sustained 107 load cycles the material is capable of enduring an infinite number of cycles provided that the service conditions are unchanged. With the development of modern ultrasonic fatigue testing equipment it became possible to experimentally establish VHCF behaviour of various materials. For most of them the existence of the fatigue limit at 107 load cycles has been proved wrong and their fatigue strength continues to decrease with increasing number of load cycles. This report describes very long life fatigue properties of most commonly used engineering materials including aluminium, titanium, nickel alloys and various types of steel.
Supplementing corn-soybean meal diets with microbial phytase maximizes phytate phosphorus utilization by weanling pigs1 (1993)

Two experiments were conducted with crossbred weanling pigs to determine the optimal dietary supplement of Aspergillus niger phytase activity to a low-P, corn-soybean meal basal diet (BD). In Exp. 1, 50 pigs (7.61 ± .56 kg BW) received the BD supplemented with 750, 1,050, 1,250, or 1,350 phytase units (PU)/g, or .21% P as mono-dibasic calcium phosphate (MDCaP) for 4 wk. In Exp. 2, 12 pigs (6.39 ± .74 kg BW) were individually housed in metabolism cages and received BD, BD plus the optimal phytase activity (1,200 PU/g), or BD plus .21% P as MDCaP for 2 wk. In Exp. 1, additions of phytase > 1,050 PU/g of BD did not improve ADG, ADFI, gain/feed, or plasma AP activity. Quadratic relationships between dietary phytase activity and these measures were found and their stationary points were at approximately 1,200 PU/g of BD. Estimated maximum responses of these measures in pigs fed phytase were ≥ 90% compared with MDCaP. Pigs fed 1,250 PU/g of BD maintained normal plasma P and Ca concentrations. In Exp. 2, pigs that received 1,200 PU/g of BD utilized dietary P more effectively (P < .05) than pigs fed the BD or the BD plus MDCaP. Although they consumed 44% less P per day, these pigs retained only 7% less P than pigs that received MDCaP. One thousand units of phytase activity supported retention of 1.1 mg of P from the BD, and this level of phytase supplementation was equivalent in effect to .91 mg of P from MDCaP.(ABSTRACT TRUNCATED AT 250 WORDS)
A review of spatial reasoning and interaction for real-world robotics (2017)

Truly universal helper robots capable of coping with unknown, unstructured environments must be capable of spatial reasoning, i.e. establishing geometric relations between objects and locations, expressing those in terms understandable by humans. It is therefore desirable that spatial and semantic environment representations are tightly interlinked. 3D robotic mapping and the generation of consistent metric representations of space are highly useful for navigation and exploration, but they do not capture symbol-level information about the environment. This is, however, essential for reasoning, and enables interaction via natural language, which is arguably the most common and natural communication channel used and understood by humans. This article presents a review of research in three major fields relevant for this discussion of spatial reasoning and interaction. Firstly, dialogue systems are an integral part of modern approaches to situated human–robot interaction. Secondly, interactive robots must be equipped with environment representations and reasoning methods that are suitable for both navigation and task fulfillment, as well as for interaction with human partners. Thirdly, at the interface between these domains are systems that ground language in systemic environment representation and which allow the integration of information from natural language descriptions into robotic maps. For each of these areas, important approaches are outlined and relations between the fields are highlighted, and challenging applications as well as open problems are discussed.
Genome-wide identification of differentially expressed genes under water deficit stress in upland cotton (Gossypium hirsutum L.) (2012)

In this study, we detected differentially expressed transcript derived fragments from water deficit stressed root and leaf tissues in tetraploid cotton and provided their gene ontology, functional/biological distribution, and possible roles of gene duplication. This discovery demonstrates complex mechanisms involved with polyploid cotton's transcriptome response to naturally occurring field water deficit stress. The genes identified in this study will provide candidate targets to manipulate the water use characteristics of cotton at the molecular level.