gebhart/patrepeval huggingface dataset:
Regression analysis of gait parameters and mobility measures in a healthy cohort for subject-specific normative values (2018)

Normalization of gait parameters and mobility measures through linear regression models augment the capability to compare subjects with varying anthropometric measurements.
Epoxy-Resin Seals for GM Counter Construction (1961)

First Page
Iridoid glycosides and insect feeding preferences: gypsy moths (Lymantria dispar, Lymantriidae) and buckeyes (Junonia coenia, Nymphalidae) (1989)

Abstract. 1. The effect of increasing concentrations of an iridoid glycoside, catalposide, was tested on a generalist and an adapted specialist lepidopteran, using artificial diets. 2. Two strains of the gypsy moth, Lymantria dispar (L.) (Lymantriidae), were tested. Larvae of a wild strain showed a negative dose‐dependent response to increasing concentrations of catalposide (up to 7.2% dry weight), while a laboratory strain showed no such pattern. Choice tests using the laboratory strain showed that these larvae often preferred diets relatively low in catalposide over those with higher concentrations. 3. In contrast, larvae of the iridoid glycoside specialist, the buckeye, Junonia coenia Hübner (Nymphalidae), showed a positive dose‐dependent response and grew better on diets with higher doses of catalposide. 4. We tested whether the improved growth of J. coenia at higher concentrations of catalposide may have been due to extra glucose yielded by hydrolysis of catalposide. Larvae were fed increasing doses of glucose equivalent to the amount potentially obtained by hydrolysing the quantities of catalposide used in the previous experiment. However, added glucose did not effect growth, suggesting that increased growth at higher catalposide concentrations was due to increased feeding rates.
Effect of SeO2 on telomerase activity in human lung carcinoma cell line GLC-82 (2003)

Objective: To observe the effect of inhibition of telomerase activity by selenium dioxide (SeO2) on lung carcinoma cell line GLC-82. Methods: TRAP-PCR-ELISA was used to study the changes of telomerase activity in human pulmonary adenocarcinoma cell line GLC-82 treated by SeO2 at the different concentrations (3, 10, 30 µmol/L) and for different times (24, 48, and 72 h). Results: SeO2 inhibited the telomerase activity of GLC-82 at the different concentrations after treatment of 24, 48 and 72 h. Conclusion: SeO2 inhibits from telomerase activity of human lung carcinoma line GLC-82. The effect of inhibition is dose-dependant and time-dependant.
Adopting a Modular Schedule? (1968)

A man who has fathered a modular schedule for his school discusses some of the characteristic labor pains and suggests how they can be moder ated.
Über zweistufige Redoxsysteme, XXX. Spektroskopische und elektrochemische Eigenschaften <i>N</i>‐substituierter 1,4‐Dihydro‐4,4‐dimethylpyridine (1982)

Abstract Das anomale Verhalten der N ‐Substituenten R = CO 2 C 2 H 5 und besonders R = CN im Redoxsystem 1 wird anhand der z. T. neu dargestellten 1,4‐Dihydropyridine 2 als Modelle für 1 RED untersucht. Es zeigen sich keine Besonderheiten, so daß die spezifischen Effekte in 1 den höheren Oxidationsstufen zuzuschreiben sind.
U.S.-China Trade Warâ€™s Impact on Taiwanâ€™s Exports of Major Goods and Export Amount to Major Countries/Regions (2020)

Taiwan is an export-oriented island economy. Because foreign trade plays a significant role in the countryâ€™s economic development, the current U.S.-China trade conflict has greatly affected it as well as global economic and trade development. This study thus used Financial and Trade Statistics data of the Ministry of Finance, Taiwan, R.O.C (2020) and analyzed the major export categories of Taiwan and export amounts of major countries/regions in 2018 and 2019 to explore the impact of the U.S.-China trade war. According to the analysis results, conclusions and relevant specific suggestions are put forward for the government and industry as a reference.Â Â JEL classification numbers: F14, F18.Â Keywords: U.S.-China Trade War, Export, Island Economy.
Design and implement a safe method for isolating memory based on Xen cloud environment (2016)

In view of the present cloud security problem which has been becoming one of the major obstacles hindering the development of the cloud increasingly, put forward a kind of technology implementation of memory security isolation based on Xen. And based on the Xen virtual machine monitor system, analysis the implementation approach of memory virtualization in the model, using Xen virtualization system memory's super calls and authorization table mechanism, design the security memory isolation system with the basics of virtual machine manager internal implementation of access control module (ACM). Experiments show that the system can effectively isolate the memory data between different customer domain OS illegal access.
Impotence Is Not Always Psychogenic (1980)

The concept that impotence is psychogenic in 95% of cases is reconsidered. Screening serum testosterone levels of 105 consecutive patients with impotence showed that 37 patients had previously unsuspected disorders of the hypothalamic-pituitary-gonadal axis. Twenty patients had hypogonadotropic-hypogonadism, seven had hypergonadotropic-hypogonadism, eight had hyperprolactinemia, and two had occult hyperthyroidism. Once the specific defect was defined, appropriate therapy was instituted, and potency was restored in 33 patients. Screening serum testosterone levels is useful in identifying hypothalamic-pituitary-gonadal dysfunction in patients with impotence.
Development of a Nested PCR for Detection of <i>Cryptococcus neoformans</i> in Cerebrospinal Fluid (1998)

We report the development of a nested-PCR-based assay for the detection of Cryptococcus neoformans in cerebrospinal fluid. The specificity and sensitivity of the test were assessed. The technique was then applied to 40 cerebrospinal fluid samples. We obtained positive reactions for all 21 clinical samples from patients who had been previously diagnosed as having cryptococcal meningitis by conventional techniques and negative reactions for all 19 negative controls. Nested PCR is here compared with other diagnostic methods currently used in patients' follow-up exams during anticryptococcal therapy.
TGFβ induced FoxP3+ regulatory cells prevent Th1 mediated colitis in vivo (2004)

Loss of immune tolerance is a key feature at the basis of many autoimmune human diseases such as IBDs. Tolerance is achieved through both central deletion of self reactive T cells and the peripheral control of potentially autoaggressive effector cells by means of specialized regulatory cells. A subgroup of these regulatory cells, characterized by the constitutive expression of CD25, GITR and CTLA–4, have been recently found to express the transcription factor FoxP3, being responsible for the regulatory phenotype of these cells.
The Role of Ventromedial Prefrontal Cortex in the Recovery of Extinguished Fear (2000)

Conditioned fear responses to a tone paired with footshock extinguish when the tone is presented repeatedly in the absence of shock. Rather than erase the tone-shock association, extinction is thought to involve new learning accompanied by inhibition of conditioned responding. Despite much interest in extinction from a clinical perspective, little is known about the neural circuits that are involved. Although the prefrontal cortex has a well established role in the inhibition of inappropriate behaviors, previous reports have disagreed as to the role of the ventromedial prefrontal cortex (vmPFC) in extinction. We have reexamined the effects of electrolytic vmPFC lesions made before training on the acquisition, extinction, and recovery of conditioned fear responses in a 2 d experiment. On Day 1 vmPFC lesions had no effect on acquisition or extinction of conditioned freezing and suppression of bar pressing. On Day 2 sham rats recovered only 27% of their acquired freezing, whereas vmPFC-lesioned rats recovered 86%, which was indistinguishable from a control group that never received extinction. The high recovery in lesioned rats could not be attributed to decreased motivation or altered sensitivity to footshock. vmPFC lesions that spared the caudal infralimbic (IL) nucleus had no effect. Thus, the vmPFC (particularly the IL nucleus) is not necessary for expression of extinction, but it is necessary for the recall of extinction learning after a long delay. These data suggest a role of the vmPFC in consolidation of extinction learning or the recall of contexts in which extinction took place.
Wireless EEG signals based Neuromarketing system using Fast Fourier Transform (FFT) (2014)

This work aims to identify the most preferred brand on automotive in Malaysia through wireless EEG signals. A group of four major vehicle brand advertisements such as Toyota, Audi, Proton and Suzuki is considered on this work. An advertisement (video) of above said brands were used to simulate the subjects (9 male and 3 female with age range of 22–24 years) and the brain signal responses for the stimuli were collected using 14 channel wireless Emotiv headset with a sampling frequency of 128 Hz. The acquired signals are preprocessed using 4th order Butterworth band pass filter with a cut off frequency of 0.5 Hz–60 Hz and smoothed using Surface Laplacian filter. The alpha frequency band (8 Hz–13 Hz) of EEG signal information has been extracted using the Butterworth 4th order filter. The frequency spectrum of Alpha band is obtained through Fast Fourier Transform (FFT) to extract three statistical features such as power spectral density (PSD), spectral energy (SE) and spectral centroid (SC) from the EEG signals. Extracted features on all the subjects over four different advertisement stimuli are used to develop the feature vector. This feature vector is further given to a two non-linear classifiers namely K Nearest Neighbor (KNN) and Probabilistic Neural Network (PNN) for classifying the subject intention on advertisements. This present experimental results indicate that, the subjects are mostly inspired on Toyota brand vehicles compared to other brands. The maximum mean classification rate of 96.62% is achieved using PSD feature and PNN classifier.
Selection and binding of peptides to human transporters associated with antigen processing and rat cim-a and -b (1996)

Cytotoxic T lymphocytes recognize antigenic peptides presented by MHC class I molecules. The peptides are generated in the cytosol by proteasomes, and probably also other proteases, and are then translocated into the endoplasmic reticulum (ER) lumen. The transporters associated with Ag processing (TAP) are key molecules for transporting peptides from the cytosol to the lumen of the ER. Using semipermeabilized cells, TAP-dependent peptide translocation was demonstrated, and the selectivity of peptide translocation was based on the carboxyl-terminal amino acid of peptides. We have examined peptide binding proteins in the ER membrane and the selection of peptides for binding to TAP by using a panel of peptides of different sequences and carboxyl-termini as well as peptides containing D amino acids. Peptides bound to TAP molecules in the absence of ATP. The presence of ATP induced binding of peptides to two additional membrane proteins (58 and 43 kDa). The selection of peptides by TAP molecules was based on peptide sequence and the carboxyl-terminal amino acid. Peptides containing D amino acid did not bind to TAP molecules. Rat cim-a and -b selected peptides differently, and selection was not only dependent on the carboxyl-terminal residue of the peptide, but included an influence of the peptide sequence. The different off-rates after peptide binding to TAP, indicated a dual binding step of peptide to TAP. ATP regulated the off-rate of peptides at a high affinity binding step. Our results demonstrate that the binding of peptides to TAP molecules is specific and most likely involves a multiple step pathway.
Multiple-mode resonance bands in periodically nonuniform conductor-backed coplanar waveguides (2003)

The full-wave spectral-domain technique is developed to investigate the characteristics of periodically nonuniform MIC transmission lines. The Floquet's theorem is employed to express all the field quantities in terms of the spatial harmonics, so that the boundary-value problem of a periodically nonuniform transmission line can be treated similarly to that of the uniform one. The Galerkin's method in the Fourier-spectral domain with a set of appropriate basis functions is used to obtain the numerical results for the characteristics of the sinusoidal-shaped coplanar waveguides with/without backside ground. The multiple resonance bands produced by the dominant mode as well as the higher-order modes in these periodic structures are exploited theoretically and experimentally.
Tribological behaviour of self-lubricating materials at high temperatures (2017)

Self-lubricating materials are becoming more widespread in fields like metal forming or power generation due to the inability to use conventional lubricants in high-temperature (HT) applications. In an effort to summarise the progress done in this field, a detailed literature review has been carried out, ranging from micron-thickness thin films to hardfacings and bulk materials, and classified by the reported solid lubricants. Moreover, the most-cited deposition techniques have been reviewed for each lubricant class in addition to their advantages and limitations. HT friction and wear data for self-lubricating materials have also been examined in order to identify effective lubrication ranges and general trends in their tribological behaviour, which is expected to be useful for researchers interested in this field. Finally, several apparent research gaps have been described, with suggestions for new experimental work that could lead to the development of new high-temperature self-lubricating materials.
Aramburu y la dignidad. (2012)

Las grandes obras del escritor han apuntado siempre a salvaguardar el valor del individuo frente a la ideologia.
Cartilage degradation in knee osteoarthritis patients with elevated levels of urinary collagen type II C-telopeptide fragments (2000)

peer reviewed
Historical Spectrum Sensing Data Mining for Cognitive Radio Enabled Vehicular Ad-Hoc Networks (2015)

In vehicular ad-hoc network (VANET), the reliability of communication is associated with driving safety. However, research shows that the safety-message transmission in VANET may be congested under some urgent communication cases. More spectrum resource is an effective way to solve transmission congestion. Hence, we introduce cognitive radio (CR) enabled VANET (CR-VANET), where CR device can detect possible idle spectrum for VANET communications and assist to timely broadcast safety-message. Given high-speed mobility of vehicles and dynamically-changing availability of channels, a novel prediction algorithm is proposed to pick out the channel with the greatest probability of availability, which can meet the quality of service (QoS) requirement of urgent communications and effectively avoid conflict with licensed users. Specifically, the spatiotemporal correlations among historical spectrum sensing data are exploited to form prior knowledge of channel availability probability, and Bayesian inference is used to derive posterior probability of channel availability. Comparing with other spectrum detection methods, the proposed algorithm has more than 8 percent detection performance improvement at false alarm probability 0.2, and thus can avoid access conflict with licensed users dramatically. Furthermore, the proposed algorithm always has larger packet reception probability (PRP) and lower transmission delay compared with conventional VANET broadcasting. Hence, the proposed algorithm can improve reliability of safety-message transmission and enhance driving safety significantly.
Active distribution power system with multi‐terminal DC links (2016)

A fast power restoration operational scheme and relevant stabilising control is proposed for active distribution power systems with multi‐terminal DC network in replacement of the conventional normal open switches. A nine‐feeder benchmark distribution power system is established with a four‐terminal medium power DC system injected. The proposed power restoration scheme is based on the coordination among distributed control among relays, load switches, voltage source converters and autonomous operation of multi‐terminal DC system. A DC stabiliser is proposed with virtual impedance method to damp out potential oscillation caused by constant power load terminals. The proposed system and controls are validated by frequency domain state‐space model and time‐domain case study with Matlab/Simulink.
UV-Light Exposed Prion Protein Fails to Form Amyloid Fibrils (2008)

Amyloid fibril formation involves three steps; structural perturbation, nucleation and elongation. We have investigated amyloidogenesis using prion protein as a model system and UV-light as a structural perturbant. We find that UV-exposed prion protein fails to form amyloid fibrils. Interestingly, if provided with pre-formed fibrils as seeds, UV-exposed prion protein formed amyloid fibrils albeit with slightly different morphology. Atomic force microscopy and electron microscopic studies clearly show the formation of fibrils under these conditions. Circular dichroism study shows loss in helicity in UV-exposed protein. UV-exposed prion protein fails to form amyloid fibrils. However, it remains competent for fibril extension, suggesting that UV-exposure results in loss of nucleating capability. This work opens up possibility of segregating nucleation and elongation step of amyloidogenesis, facilitating screening of new drug candidates for specifically inhibiting either of these processes. In addition, the work also highlights the importance of light-induced structural and functional alterations which are important in protein based therapeutics.
Application of X-ray computed tomography to soil science: A literature review (2008)

The study of the spatial configuration of soil, in its complexity, requires an understanding of the interrelations and interactions between the diverse soil constituents, at various levels of organization. Investigations of the spatial arrangement of the mineral and organic components of soil have benefited from the development of techniques for structural analysis. X-ray computed tomography (CT) is a non-destructive and non-invasive technique that has been successfully used for three-dimensional (3D) examination of soil. Valuable information has been obtained by the application of CT for the description and quantitative measurements of soil structure elements, especially of soil pores and pore network features. In many studies, X-ray CT has been used to investigate the hydro-physical characteristics of the soil, in a functional and temporal manner. A dynamic approach has also been utilized in the evaluation of the biotic factor influence on soil. The analysis of soil solid phases, by X-ray CT, has been challenging due to the similar X-ray attenuation of different solid constituents. However, the use of multiple X-ray energy levels has facilitated the discrimination of minerals in soil. The aim of this review and synthesis is to offer a perspective on the major issues related to application of the technique, general attempted solutions and possible directions in the utilization of X-ray CT in soil research. Relevant scanning parameters, procedures for CT image reconstruction, algorithms for the quantification of soil characteristics and results are presented for each type of application. Key words: X-ray computed tomography, energy level, spatial resolution, segmentation, soil mineral and organic constituents, soil physical and hydro-physical properties, soil biota
A technique for localized heating in tissue: an adjunct to tumor therapy. (1976)

Increasing evidence of the beneficial effects of hyperthermia in the treatment of tumors, particularly when combined with radiation therapy or chemotherapy, has created the need for practical methods of localizing heat in arbitrary tissue volumes. Heating superficial transplanted animal tumors in hot-water baths has been of considerable importance in research, but the method has very limited clinical application. Microwave diathermy and ultrasound diathermy are capable of greater penetration than external conduction heating, but are also generally limited to the heating of superficial tissue volumes. A more direct method for localized tissue heating is proposed: localized electric current fields produced with carefully specified electrode configurations. This technique, although often quite invasive, offers the possibility of heat localization in almost any treatment volume specified by the therapist. Variations in electrical and thermal properties of tissues can be exploited to improve the architecture of the treatment plan. Several electrode configurations are illustrated. Limitations of the technique are discussed.
A soft decision 16-QAM demodulation algorithm for multipath affected DCB-T systems (2005)

In 1998, the United Kingdom started the world's first commercial digital terrestrial television service. The system used was the European digital video broadcast-terrestrial (DVB-T) but due to technological constraints at the time, the system chosen was the 2K system - a system that uses 1705 carriers to convey the digital television services through a hostile terrestrial environment. Today, these constraints are no longer applicable but in order to maintain backwards compatibility to the older set top boxes, the 2K system is still used. The 2K system has the disadvantage of excluding the possibility of employing a single frequency network (SFN) - something that can help minimize the required bandwidth for television services. This paper demonstrates an observed phenomenon that explains why DVB-T fails to meet the required BER criteria and also shows how this phenomenon can be used in a computationally inexpensive technique for estimating the relative path attenuation of a multipath signal and how it can be used to estimate the parameters required for a soft decision QAM demapper.
β‐Klotho sustains postnatal Gn <scp>RH</scp> biology and spins the thread of puberty (2017)

Hypogonadotropic hypogonadism is a syndrome found to be isolated (IHH) or associated with anosmia, corresponding to the Kallmann syndrome (KS). It comprises a defect in gonadotropin-releasing hormone (GnRH) secretion and absent or delayed puberty. Genetic causes have been identified with a high genetic heterogeneity. Fibroblast growth factor receptor 1 (FGFR1), a tyrosine kinase receptor, was one of the first genes whose mutations were identified as causative in KS FGFR1 is responsible for the formation of the GnRH neuron system. Studying patients has not only allowed the identification of new etiologies for this syndrome but also helped to unravel the signaling pathways involved in the development of GnRH neurons and in GnRH control and function. The FGF21/FGFR1/Klotho B (KLB) signaling pathway mediates the response to starvation and other metabolic stresses. Preventing reproduction during nutritional deprivation is an adaptive process that is essential for the survival of species. In this work, Xu <i>et al</i> (2017), using a candidate gene approach, provide a description of the essential role played by this pathway in GnRH biology and in the pathogenesis of IHH and KS They establish a novel link between metabolism and reproduction in humans.