gebhart/patrepeval huggingface dataset:
Statistic Replacement of Lanthanide Ions in Bis‐salicylatoborate Coordination Polymers for the Deliberate Control of the Luminescence Chromaticity (2021)

Based on the strand-like coordination polymer (CP) type <sup>1</sup> <sub>∞</sub> [Ln(BSB)<sub>3</sub> (py)<sub>2</sub> ], [BSB]<sup>-</sup> =bis-salicylatoborate anion, mixed Eu/Tb-containing compounds of the constitution <sup>1</sup> <sub>∞</sub> [Eu<sub>x</sub> Tb<sub>1-x</sub> (BSB)<sub>3</sub> (py)<sub>2</sub> ] were synthesised ionothermally for a phase width of (x=0.25-0.75) and characterized regarding structure and optical properties. Previously, known only for other lanthanides, the mixed 1D-Eu/Tb-CPs show excellent options for statistic replacement of the Ln-cations during synthesis yielding solid solutions. The products are highly luminescent, with the chromaticity being a direct function of the amount of the respective Ln-ions. Corresponding to an overall addition of emission intensities, the green Tb<sup>3+</sup> emission and the red Eu<sup>3+</sup> emission allow for a chromaticity control that also includes yellow emission. Control of the luminescence colour renders them suitable examples of the versatility of statistic replacement of metal ions in coordination chemistry. In addition, crystallization of [EMIm]<sub>2</sub> [YCl<sub>5</sub> (py)] illuminates possible other products of the ionothermal reactions of [EMIm][BSB] with LnCl<sub>3</sub> constituted by components not being part of the main CPs.
A genomic analysis of Philadelphia chromosome-negative AML arising in patients with CML (2016)

Chronic myelogenous leukemia (CML) is characterized by the Philadelphia chromosome, an acquired clonal abnormality resulting from translocation of chromosomes 9 and 22, and the generation of the BCR-ABL fusion oncogene. The development of tyrosine kinase inhibitors (TKIs) has revolutionized the treatment of CML, as TKI therapy leads to inhibition of BCR-ABL activity, suppression of the BCR-ABL-containing clone and restoration of normal hematopoiesis in the vast majority of cases.
Study of Hydrogenolytic Cleavage of Peptide-Resin Benzyl Ester Bonds for Synthesis of Protected Fragments of the Human Leukocyte Interferon (1983)

Three Roe-protected fragments of the human leukocyte interferon, LeIFA, have been synthesized: I, BOC LeIFA (99-105) (BOC-Val-Ile-Gln-Gly-Val-Gly-Val); II, BOC Lei FA (116-119) (BOC-Ile-Leu-Ala-Val); III, BOC LeIFA (123-126) (BOC-Phe-Gln-Arg(Tos)-Ile). The presence of the Boc-group was desired so that these peptides could serve as intermediates in fragment condensation toward larger segments of interferon. To achieve these intermediates, a study was desirable on three methods of cleavage of the benzyl ester-polymer bonds. It was found that hydrogenolysis with hydrogen and palla­dium generated in situ was distinctly superior to transfer hydrogenation with ammonium formate or cyclohexene. An effective swelling of the peptide-resin to allow penetration of palladium acetate into the matrix and mobility of the peptide chains on the resin to expose the bonzyl ester bond to hydrogenolysis appear to be essential conditions for the best cleavage.
REGLEMENTATION ET NORMALISATION IN "PREMIER CONGRES INTERNATIONAL SUR LA VISION ET LA SECURITE ROUTIERE" (1975)

SESSION VII REGLEMENTATION ET NORMALISATION INTERNATIONAL RECOMMENDED STANDARDS FOR THE MEDICAL EXAMINATION OF DRIVERS WILL BE REVIEWED, AND A SURVEY OF NATIONAL REGULATIONS WILL BE PRESENTED, PARTICULARLY THE VARYING STANDARDS FOR VISION WILL BE OBSERVED M.ANDRASON (SWEDEN). CONDITIONS EXIGEES PAR LA REGLEMENTATION EN VIGUEUR, DANS LE DOMAINE DE LA VISION M.DUBARRY (FRANCE). LES GRAVES LACUNES DES CONTROLES D'APTITUDE J.BLUM,DAHAN,COUSTOU (FRANCE). PROBLEME DER ANFORDERUNGEN AN DAS SEHVERMOGEN IM STRASSENVERKEHR E.HEINSIUS (R.F.A.). VISUAL TRAITS IN RELATION TO DRIVER LICENSING REQUIREMENTS H.W.HOFSTETTER (U.S.A.). APTITUDE VISUELLE ET PERMIS DE CONDUIRE REGLEMENTATION EN VIGUEUR, NOTAMMENT DANS LA COMMUNAUTE EUROPEENNE M.BELICARD (FRANCE). EXIGENCES VISUELLES APPLICABLES AUX CONDUCTEURS F.ALONZO MARTINEZ (ESPAGNE). DER SEHTEST FUR KRAFTFAHRER BEIM TUV HANNOVER-EIM BEITRAG ZUR STANDARDISIERUNG VON KRAFTFAHRER SEHTESTEN W.WINCKLER (R.F.A.). SEHTESTUNG. DAS MITTEL, UM MANGEL DES SEHVERMOGENS ZU ERFASSEN G.GUILINO (RFA). VOIR FICHE GENERALE DIRR NO 105324
Addition of Arylboronic Acids to Arylpropargyl Alcohols en Route to Indenes and Quinolines (2011)

A regio- and stereoselective rhodium-catalyzed synthesis of trisubstituted allylic alcohols is described. The utility of these synthons is demonstrated in a convenient synthesis of indenes and quinolines.
THE DROUGHT MONITOR (2002)

The Drought Monitor was started in spring 1999 in response to a need for improved information about the status of drought across the United States. It serves as an example of interagency cooperation in a time of limited resources. The Drought Monitor process also illustrates the creative use of Internet technologies to disseminate authoritative information about drought and to receive regional and local input that is in turn incorporated into the product. This paper describes the Drought Monitor and the interactive process through which it is created.
Contrasting Response of Lung Parenchymal Cells to Instilled TNF α and IFN γ: The Inducibility of Specific Cell ICAM-1 In Vivo (1996)

Induction of intercellular adhesion molecule-1 (ICAM-1) by proinflammatory cytokines during inflammation plays an important role in regulating polymorphonuclear neutrophil (PMN) migration and localization. In this report, we examined the effects of tumor necrosis factor-alpha (TNF alpha) and interferon-gamma (IFN gamma) on specific lung cell expression of ICAM-1 in vivo and the accompanying morphological changes. Balb-c mice were treated with phosphate-buffered saline (PBS) alone or with PBS containing 5 micrograms TNF alpha or IFN gamma through intranasal instillation. Twenty-four hours after treatment, their lungs were processed for immunoblot analysis and electron microscope immunocytochemistry. In the normal lung, the ICAM-1 level is high on type I alveolar epithelial cells, medium on arterial and venous endothelial cells, low on type II epithelial cells and capillary endothelium, and not detectable on bronchial epithelium. Topical treatment of the lung with either TNF alpha or IFN gamma induced a 50-60% increase in total lung and alveolar ICAM-1. A dramatic increase of alveolar type II cell surface ICAM-1 was observed (> 20-fold). Both cytokines caused 2-3-fold higher ICAM-1 expression on capillary endothelial cells and a 40% increase of ICAM-1 on alveolar type I cells that was not uniform. However, due to the large total surface area of type I epithelium, type I cells contribute 70-86% of total alveolar septal ICAM-1 and > 90% of alveolar surface ICAM-1 in either treated or normal mouse lungs. Increased ICAM-1 expression was also observed on nonparenchymal endothelial and epithelial cells. Margination and sequestration of PMN in cytokine-treated lungs were observed by histologic examination, measurements of total lung myloperoxidase activity, and number of neutrophils recovered in bronchoalveolar lavage fluid. These results showed that TNF alpha and IFN gamma induce ICAM-1 expression and infiltration of neutrophils in the lung. The response of specific lung cells in terms of induction of ICAM-1 in response to cytokine stimulation varied significantly, particularly between type I and type II epithelial cells.
Synthesis of two useful, enantiomerically pure derivatives of (S)-4-hydroxy-2-cyclohexenone (1989)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSynthesis of two useful, enantiomerically pure derivatives of (S)-4-hydroxy-2-cyclohexenoneJames E. Audia, Louise Boisvert, Arthur D. Patten, Anabella Villalobos, and Samuel J. DanishefskyCite this: J. Org. Chem. 1989, 54, 15, 3738–3740Publication Date (Print):July 1, 1989Publication History Published online1 May 2002Published inissue 1 July 1989https://pubs.acs.org/doi/10.1021/jo00276a043https://doi.org/10.1021/jo00276a043research-articleACS PublicationsRequest reuse permissionsArticle Views3240Altmetric-Citations121LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
<title>Vision system for deriving 3D gripping information for a robot</title> (1994)

This paper describes a 3D vision system that allows the derivation of gripping information for a robot. Its capabilities are demonstrated in a benchmark that consisted in the task of clearing cafeteria trays. The system can handle a fair number of objects with substantial mutual occlusion. The objects can be transparent and specularly reflecting. In order to guarantee true 3D object recognition the system used three cameras. Two of these take `skylines' of the tray with dishes and cutlery pieces on it from the side, and a third camera takes a gray-level image from above. A ROI in each of the skyline contours pertaining to the highest object is analyzed, and features are extracted. Information from all three images is combined in a rule-based evidence accumulation scheme to determine the identity of the object in focus. The same features that voted for this object also allow the determination of its position and orientation. Finally the gripping points are calculated, depending on object, pose, and approach direction.
Comparative studies of temperature dependence of G-band peak in single walled carbon nanotube and highly oriented pyrolytic graphite (2005)

Thermal stability and temperature-dependent properties of carbon nanotubes are very important for the fabrication of carbon nanotube-based devices. High purity of carbon nanotube matrix was achieved by sieving through Anatop filters. The temperature dependence of G-band in single-wall-carbon-nanotubes matrices and highly oriented pyrolytic graphite is investigated. It was found that the former had significantly higher magnitude of temperature coefficient (−0.044cm−1∕K) compared to the latter (−0.031cm−1∕K). A hypothesis is proposed based on their structural differences in C–C bonds for explaining this variation.
Carex radiata (Wahlenb.) Small (2002)

https://thekeep.eiu.edu/herbarium_specimens_byname/10671/thumbnail.jpg
Ketene Acetals. XXVIII. The Dehalogenation of α,α-Dibromoacetals. Isopropenylketene Diethylacetal (1952)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTKetene Acetals. XXVIII. The Dehalogenation of α,α-Dibromoacetals. Isopropenylketene DiethylacetalS. M. McElvain and Leo R. MorrisCite this: J. Am. Chem. Soc. 1952, 74, 10, 2657–2662Publication Date (Print):May 1, 1952Publication History Published online1 May 2002Published inissue 1 May 1952https://pubs.acs.org/doi/10.1021/ja01130a056https://doi.org/10.1021/ja01130a056research-articleACS PublicationsRequest reuse permissionsArticle Views193Altmetric-Citations22LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Serum cystatin C as a marker of glomerular filtration rate (2001)

Division of Renal Diseases, Brown University School of Medicine, Rhode Island and The Miriam Hospitals, Providence, Rhode Island, USA Correspondence to Professor Lance D. Dworkin, Director, Division of Renal Diseases, Brown University School of Medicine, Rhode Island Hospital, 593 Eddy Street, Providence, RI 02903, USA. Tel: +1 401 444 6844; fax: +1 401 444 6849; e-mail: [email protected] Abbreviation GFR: glomerular filtration rate
Quantification of MicroCT Image Intensity and Nanoparticle Concentration in Agarose Gel (2012)

In recent years, magnetic nanoparticle hyperthermia has attracted a lot of attentions in cancer treatment due to its ability to confine heat within the tumor with minimal collateral thermal damage to the surrounding healthy tissue.1–4 The success of the treatment using magnetic nanoparticles depends on careful planning of the heating duration and achieved temperature elevations. It has been demonstrated by previous research that the generated volumetric heat generation rate or Specific Absorption Rate (SAR) should be proportional to the nanoparticle concentration distribution in the tumors. The difficulty encountered by bioengineers is that the nanoparticle concentration distribution is often unknown, since the tissue is opaque. Recently, high-resolution microCT imaging technique has been used to visualize magnetic nanoparticle distribution in tumors. MicroCT has been shown to generate detailed 3-D density variations induced by nanoparticle depositions in both tissue-equivalent gels and tumor tissues.5–6 However, experimental studies are still needed to quantify the relationship between the microCT pixel index number shown in the scanned images and the actual nanoparticle concentrations.
Investigation of the Relationship between Whole-Wafer Strength and Control of Its Edge Engineering (2009)

Silicon wafer breakage has become a major concern for all semiconductor fabrication lines because it is brittle, and thus high stresses are easily induced in its manufacture. The production cost of devices significantly increases even for a breakage loss of a few percent if wafers are broken near completion. Even wafer breakage near the beginning of the process is significant. In this investigation, we develop a brand new approach to reducing breakage by using a charge-coupled device (CCD) to capture the cross-section image of the wafer at its edge; the data measured at the edge can be used to determine overall wafer strength. Analysis of the image of the wafer edge is used to characterize silicon strength, and a simple drop test is conducted to elucidate wafer failure, improving our understanding of the accumulation of stress in the wafer bulk before failure. We also describe many of the improvements that have resulted in the virtual elimination of wafer breakage due to unidentified causes. Our analysis gives the optimal front size (B1), edge widths (A1,A2), and bevel angle (θ) for the edge profiles of wafers to prevent wafer breakage. Briefly, when a suitable material and suitable process control approaches are utilized, silicon wafer breakage can be prevented. This is the first investigation providing evidence that whole-wafer strength is an important issue. We present a physical model to explain why wafer fracture has become an increasingly serious problem as the diameter of wafers has increased. The control of wafer edge geometry has been demonstrated to be an effective means of protecting wafers with large diameters against breakage. This model reveals that the breakage rate of wafers can be reduced by controlling the uniformity of the differences between the front size and the rear edge widths during the wafer manufacturing process.
Modeling and experimental realization of modelocked VECSEL producing high power sub-100 fs pulses (2018)

A microscopic many-body theory driven design and optimization supports the experimental demonstration of sub-100 fs pulse duration directly from a semiconductor laser. A passively modelocked vertical external cavity surface emitting laser producing a pulse duration of 95 fs at a central wavelength of 1025 nm is demonstrated. The semiconductor gain and absorber structures used in the experiment are numerically optimized by modelling the pulse formation dynamic of the system. The resulting structure design is described in detail and the physical limitations in terms of pulse duration and power are discussed. Using a ring cavity geometry, a stable colliding pulse modelocking regime with an output power of 90 mW per beam at a repetition rate of 2.2 GHz is demonstrated. The output pulses are thoroughly characterized and are in good agreement with our predictive model.
ChemInform Abstract: SILYL VARIATION OF N‐AMIDOALKYLATION (1983)

Abstract In den N‐Trimethylsilylderivaten (I), (IV) oder (VI) Iäßt sich die Trimethylsilylgruppe durch Umsetzung mit N‐(′hlormethylamiden gegen den Amidomethylrest austauschen.
Shelf Stable Egg-Based Products Processed By Ultra High Pressure Technology (2008)

Abstract : The U.S. Army and Marine Corps are in search of more satisfactory shelf stable, egg-based breakfast entry for group or individual military rations. The provision of combat ration egg products with a fresh, familiar home-style taste, especially as breakfast food, has been a significant challenge for the military, as commercial retort processing typically results in foods with undesirable flavors, greenish-grey discoloration, and detrimental changes in texture and syneresis. In this project, High Pressure Thermal Sterilization (HP/TS), also known as pressure assisted thermal processing (PATP), is presented as an alternative to commercial sterilization techniques, as a promising approach to providing commercially sterile precooked egg products that can be stored at room temperature. The team focused on identifying the effect of HP/TS conditions on commercial and modified egg patty formulations. Two processing strategies were initially proposed for egg-based product commercial sterilization: a) to facilitate FDA approval, a standard thermal sterilization treatment at process temperature 121 C accelerated by the application of 700MPa with holding time 3 min was evaluated; b) thermal HP/TS treatment using lower temperature than in a) with increased holding time. Furthermore, inactivation studies, incubation tests, packaging identification, and compression heating studies gave a deeper understanding of the process.
Homeostatic regulation of sleep in a genetic model of depression in the mouse : Effects of muscarinic and 5HT1a receptor activation. (2006)

International audience
Sphingolipid base metabolism. Stereospecific uptake of proton in the enzymatic conversion of sphinganine 1-phosphate to ethanolamine 1-phosphate. (1976)

D-erythro-(2S, 3R)-Sphinganine 1-phosphate was incubated with rat liver microsomes in the presence of tritiated water. [3H]Ethanolamine 1-phosphate was isolated and converted, through a combination of enzymatic and chemical reactions, to [3H]glycine. The labeled glycine was incubated with D-amino acid oxidase, an enzyme which, in the catalysis of the conversion of glycine to glyoxylic acid, specifically removes the hydrogen in the S configuration at carbon atom 2 of glycine. Essentially complete retention of the labeled hydrogen occurred upon conversion to glyoxylic acid. The combined results indicate that the conversion of D-erythro-(2S,3R)-sphinganine 1-phosphate to palmitaldehyde and ethanolamine 1-phosphate, catalyzed by sphinganine-1-phosphate lyase of rat liver microsomes, proceeds with the stereospecific incorporation of 1 atom of solvent hydrogen into the R configuration of ethanolamine 1-phosphate.
Fetuin-A Correlates with Cortical Demyelination and is a CSF Biomarker of Disease Activity in Progressive MS (P5.214) (2015)

OBJECTIVE: To investigate whether CSF Fetuin-A levels are a biomarker of disease activity in progressive MS. BACKGROUND: Disease activity in progressive MS is assessed by clinical findings or changes in MRI. However, these measures are not always objective and disease worsening often does not correlate with MRI findings in progressive MS. CSF Fetuin-A has been identified as a biomarker for disease activity in MS, showing significantly elevated levels in patients with active disease. Decreased CSF Fetuin-A levels also correlated with therapeutic response to natalizumab. Our previous studies have shown upregulated Fetuin-A expression in white matter demyelination and in neighboring grey matter in MS brain tissue. In this study, we specifically investigated CSF Fetuin-A levels in patients with progressive MS and examined Fetuin-A expression in grey matter demyelination thought to be a key feature of progressive MS. DESIGN/METHODS: Fetuin-A levels were measured by ELISA in CSF from secondary progressive (n=75) and primary progressive (n=40) MS patients. Disease activity was determined by clinical examination, change in EDSS, and MRI changes over a period of 24 months. To investigate Fetuin-A in MS grey matter, 66 cortical lesions were identified in 46 post-mortem MS brain tissue samples. Cortical lesions were characterized by immunohistochemistry for PLP and Fetuin-A. RESULTS: CSF Fetuin-A was significantly elevated progressive patients with active disease, compared to patients with inactive disease. Furthermore, only 3[percnt] of progressive patients with active disease had change in MRI, whereas 84[percnt] showed elevated CSF Fetuin-A. Neuronal expression of Fetuin-A was increased in 62[percnt] of cortical lesions, where it correlated with a loss of PLP. Increased Fetuin-A positivity occurred most frequently in Type III and IV subpial lesions (72[percnt] and 75[percnt], respectively). CONCLUSIONS: Our results indicate that Fetuin-A represents a quantifiable CSF biomarker of disease activity that appears to correlate with grey matter pathology in MS.
Localization of distinct reflections in rooms using spherical microphone array eigenbeam processing (2012)

This paper presents an experimental and comparative study of several spherical microphone array eigenbeam (EB) processing techniques for localization of early reflections in room acoustic environments, which is a relevant research topic in both audio signal processing and room acoustics. This paper focuses on steered beamformer-based and subspace-based localization techniques implemented in the spherical EB domain, including the plane-wave decomposition, eigenbeam delay and sum, eigenbeam minimum variance distortionless response, eigenbeam multiple signal classification (EB-MUSIC), and eigenbeam estimation of signal parameters via rotational invariance techniques (EB-ESPRIT) methods. The directions of arrival of the original sound source and the associated reflection signals in acoustic environments are estimated from acoustic maps of the rooms, which are obtained using a spherical microphone array. The EB-domain-based frequency smoothing and white noise gain control techniques are derived and employed to improve the performance and robustness of reflection localization. The applicability of the presented methods in practice is confirmed by experiments carried out in real rooms.