gebhart/patrepeval huggingface dataset:
[Calcium-transporting systems and calcium regulation in cardiomyocytes]. (2001)

The review systematizes and analyzes recent data about the role of different Ca(2+)-transport mechanisms in the regulation of Ca2+ metabolism and functional activity of the cardiomyocytes. During the cardiac action potential, Ca2+ enters the cardiomyocytes through sarcolemmal L-type calcium channels and via the Na+/Ca2+ exchange. This Ca2+ activates the release of additional Ca2+ from the sarcoplasmic reticulum. The sum of calcium from sarcolemmal influxes and sarcoplasmic release produces contractile effect. For the occurrence of relaxation, Ca2+ remove from the cytoplasm by three mechanisms, namely, sarcoplasmic Ca2+ pump, Na+/Ca2+ exchange and sarcolemmal Ca2+ pump. In this review, the structural and functional properties of the Ca2+ transport systems in the sarcolemmal membranes, sarcoplasmic reticulum and mitochondria are discussed. In addition alterations in regulation of intracellular calcium by activation of beta- and alpha-adrenergic receptors are consider.
Periodical Records on Punched Cards at AERE Library, Harwell (1969)

The periodical and serial publications for the main library at AERE and for its eighteen divisional libraries are all purchased, processed and catalogued centrally by the acquisition and cataloguing section of the main library. At present the number of titles of periodicals and serial publications being received is 1, 875. Many titles are also received in multiple copies. For effective administrative control up‐to‐date listings of the current periodical subscriptions of the divisional libraries are required annually in addition to lists of periodicals obtained through each supplier. The majority of titles purchased are ordered through one main agent, with the exception of those purchased directly from H.M. Stationery Office. A smaller proportion of titles is presented, and a very few purchased, for various reasons, direct from the publisher.
Fatigue Testing of Drillpipe (1994)

Summary Twenty-nine tests in air and 27 tests in a 3.5% NaCl solution were conducted to test the fatigue strength of Grade E 4.5-in.-OD, 16.6-lbm/ft [114-mm-OD, 24.7-kg/m] drillpipe. The effects of stress range, mean stress, corrosion, and upset geometry were tested on the drillpipe body alone and on specimens that included the tool joint, upset, and drillpipe body. Stress range and mean stress effects were significant in noncorrosive and corrosive environments. The effect of upset geometry was minimal on an external upset compared with that on an internal/external upset. Among the specimens that failed, grinding marks on the drillpipe surface, which occurred during inspection at the mill, caused failure of about 60% of the specimens. Grinding created a notch effect and induced a detrimental residual-stress pattern on the pipe surface, which decreased drillpipe fatigue life. API guidelines for cumulative fatigue of Range 2 drillpipe were evaluated in light of these experimental test results and were found to be unsafe for drilling in noncorrosive conditions and possibly too conservative for corrosive conditions.
Enhanced repellency of binary mixtures of <i>Zanthoxylum piperitum</i> pericarp steam distillate or <i>Zanthoxylum armatum</i> seed oil constituents and <i>Calophyllum inophyllum</i> nut oil and their aerosols to <i>Stomoxys calcitrans</i> (2010)

Mixtures formulated from ZP-SD, ZA-SO or bioactive constituents and CI-NO could be useful as potential repellents for the control of stable fly populations in light of global efforts to reduce the level of highly toxic synthetic repellents.
Brain Uptake of a Zidovudine Prodrug after Nasal Administration of Solid Lipid Microparticles (2014)

Our previous results demonstrated that a prodrug obtained by the conjugation of the antiretroviral drug zidovudine (AZT) with ursodeoxycholic acid (UDCA) represents a potential carrier for AZT in the central nervous system, thus possibly increasing AZT efficiency as an anti-HIV drug. Based on these results and in order to enhance AZT brain targeting, the present study focuses on solid lipid microparticles (SLMs) as a carrier system for the nasal administration of UDCA-AZT prodrug. SLMs were produced by the hot emulsion technique, using tristearin and stearic acid as lipidic carriers, whose mean diameters were 16 and 7 μm, respectively. SLMs were of spherical shape, and their prodrug loading was 0.57 ± 0.03% (w/w, tristearin based) and 1.84 ± 0.02% (w/w, stearic acid based). The tristearin SLMs were able to control the prodrug release, whereas the stearic acid SLMs induced a significant increase of the dissolution rate of the free prodrug. The free prodrug was rapidly hydrolyzed in rat liver homogenates with a half-life of 2.7 ± 0.14 min (process completed within 30 min). The tristearin SLMs markedly enhanced the stability of the prodrug (75% of the prodrug still present after 30 min), whereas the stabilization effect of the stearic acid SLMs was lower (14% of the prodrug still present after 30 min). No AZT and UDCA-AZT were detected in the rat cerebrospinal fluid (CSF) after an intravenous prodrug administration (200 μg). Conversely, the nasal administration of stearic acid based SLMs induced the uptake of the prodrug in the CSF, demonstrating the existence of a direct nose-CNS pathway. In the presence of chitosan, the CSF prodrug uptake increased six times, up to 1.5 μg/mL within 150 min after nasal administration. The loaded SLMs appear therefore as a promising nasal formulation for selective zidovudine brain uptake.
Effect of Ni<sup>2+</sup> on Chromium Electrodeposition in Cr(III) Plating Bath (2010)

A small amount of nickel ions is added to trivalent chromium chloride plating bath to study effect of Ni ions on trivalent chromium electrodeposition. The obtained Cr-Ni alloy coatings and Cr coatings are characterized by means of EDS and SEM. Cathodic polarization curves of trivalent chromium chloride plating bath show that right amount of Ni ions contained in bath make the LSV more positive, exerting a catalytic effect on electrodeposition of Cr ( ) ions. EDS results of the obtained coatings also demonstrate the catalytic effect of Ni ions on trivalent chromium electrodeposition. Analysis of SEM indicate that the surface morphology of coatings obtained from Cr( ) bath containing 0.03g/L Ni2+ bath are similar to the ones obtained from pure Cr( ) ions bath.
Assessing Consumer Fraud Risk in Insurance Claims: An Unsupervised Learning Technique Using Discrete and Continuous Predictor Variables (2009)

We present an unsupervised learning method for classifying consumer insurance claims according to their suspiciousness of fraud versus nonfraud. The predictor variables contained within a claim file that are used in this analysis can be binary, ordinal categorical, or continuous variates. They are constructed such that the ordinal position of the response to the predictor variable bears a monotonic relationship with the fraud suspicion of the claim. Thus, although no individual variable is of itself assumed to be determinative of fraud, each of the individual variables gives a hint or indication as to the suspiciousness of fraud for the overall claim file. The presented method statistically concatenates the totality of these hints to make an overall assessment of the ranking of fraud risk for the claim files without using any a priori fraud-classified or labeled subset of data. We first present a scoring method for the predictor variables that puts all the variables (whether binary red flag indicators, ordinal categorical variables with different categories of possible response values, or continuous variables) onto a common 1 to 1 scale for comparison and further use. This allows us to aggregate variables with disparate numbers of potential values. We next show how to concatenate the individual variables and obtain a measure of variable worth for fraud detection, and then how to obtain an overall holistic claim file suspicion value capable of being used to rank the claim files for determining which claims to pay and the order in which to investigate claims further for fraud. The proposed method provides three useful outputs not usually available with other unsupervised methods: (1) an ordinal measure of overall claim file fraud suspicion level, (2) a measure of the importance of each individual predictor variable in determining the overall suspicion levels of claims, and (3) a classification function capable of being applied to existing claims as well as new incoming claims. The overall claim file score is also available to be correlated with exogenous variables such as claimant demographics or high volume physician or lawyer involvement. We illustrate that the incorporation of continuous variables in their continuous form helps classification and that the method has internal and external validity via empirical analysis of real data sets. A detailed application to automobile bodily injury fraud detection is presented.
Access control management of the cloud service platform (2014)

One of the design goals of the Cloud Service Platform was to help application developers to create their applications easier by providing reusable service components in the form of web services, such as, RESTful web services or web services based on SOAP. The Cloud Service Platform is designed to target to the communication and collaboration domain so that it provides service components having functionalities such as Email, short messaging, file cloud, third-party call, wiki, and etc. Therefore application developers can utilize these service functionalities by requesting the resources using HTTP methods outside the Cloud Service Platform (CSP). Therefore, the access to service components plugged into the CSP should be managed and the authorization process for the requesting applications is needed. We specify the relationship between applications and service components using service key, which is the unique identifier for an application and a service component. In addition, we define additional HTTP headers for authorization of the requesting application and utilize these headers for access control to service components. In this paper, we introduce the Cloud Service Platform and describe the mechanism of the access control management for service components on the Cloud Service Platform.
Solvent- and Catalyst-Free Microwave-Assisted Decarboxylation of Malonic Acid Derivatives (2017)

It has been found that microwave assisted decarboxylation of malonic acid derivatives can be achieved under solvent-free and catalyst free conditions. This new method produces the corresponding carboxylic acid in a pure manner and with a high yield in a very short reaction time: 3 - 10 min. In general terms, the condition under which this reaction is carried out accelerates the decarboxylation significantly of a series of disubstituted malonic acid derivatives, and makes this new process efficient, easy and environmentally friendly.
Optimize cloud computations using edge computing (2017)

The IoT devices captures data and sends it to Cloud for computation but data transfer process from IoT device to Cloud can take lot of time if volume of data is large. Therefore, it makes sense to process captured data locally at IoT edge node to avoid latency. In Edge Computing, the Gateway stores data and perform computations along with traffic aggregation and routing. While Edge analytics allows pre-processing and filtering of the data closer to where it's being created but the data which falls within normal range can be stored in low cost IoT storage and abnormal readings will be sent to Data Lake or in-memory database. Edge Computing will boost traditional Cloud computing model with service nodes placed at the network edges. It will help traditional data center cloud models by reducing latency and increased bandwidth. In future computation and data processing power will slowly shift towards edge devices like sensors, drones, driverless cars etc. Playing augmented reality, 3D video games, content-based video analysis is a challenge on mobile phone due to limited processing power and battery life. Realtime analysis of massive sensor data is needed in industries like manufacturing, mining, transportation to detect anomalies and send alerts. Therefore, Edge Computing and Cloud computing are likely to follow more of a hybrid approach and complement each other. This paper talks about Edge computing architecture, computational offloading approaches, Edge Computing challenges and benefits etc.
Índice do Volume 97 (2016)

Este indice refere-se as materias do volume 96 (numeros 245, 246 e 247) da Revista Brasileira de Estudos Pedagogicos. Divide-se em tres partes, de acordo com os diferentes pontos de acesso: Assuntos, Autores e Titulos.
A queuing model for service selection of multi-classes QoS-aware Web services (2005)

The initial specifications of Web services cope with the issues of service publishing and service discovery but not with the issue of service selection. Service discovery, handled by UDDI and WSDL, alone is not sufficient to find the most appropriate server that can deliver customers' required quality of service (QoS). In this paper, we consider a broker-based approach to provide QoS support in Web services and deal with the selection issue. The broker may implement various selection policies that can range from static policies to dynamic ones, which take into account the current state of servers. Besides, servers may deliver different levels of service to their customers. We model this QoS broker-based scheme by a multi-class queuing model and we study its performance with a probabilistic splitting policy for server selection.
ARTIFICIAL CULTURE TECHNIQUES FOR REARING LARVAE OF THE CHALCIDOID PARASITE, <i>BRACHYMERIA INTERMEDIA</i> (1980)

The respiration of pupae of Trichoplusia ni decreased considerably following parasitization by the chalcidoid Brachymeria intermedia. Furthermore, the process of host tissue development appeared to be arrested within 48 hr indicating that this parasite quickly kills the host insect. The rate of oxygen consumption of parasitized pupae corresponded well with the observed development of the parasite. Parasite larvae fed actively and grew on conventional defined artificial media and larval development was completed on several diets of variable composition. However, following the elimination of the meconium most individuals died as prepupae. Few pupae were obtained and no adults emerged. Survival appeared to correlate with the observable protein content of developing larvae and possible factors influencing further development were discussed. RÉSUMÉ ETUDES PRELIMINAIRES SUR LE DEVELOPPEMENT DE TECHNIQUES D'ELEVAGES ARTIFICIELS DU CHALCIDIEN PARASITOIDE , BRACHYMERIA INTERMEDIA NEES La respiration des chrysalides de Trichoplusia ni diminue brutalement après attaque par Brachymeria intermedia. De plus, le développement des tissus de l'hôte paraît être arreté en 48 h, montrant que ce parasite tue rapidement l'insecte hôte. Le taux de consommation de la nymphe parasitée correspond bien au développement observé du parasite. Les larves du parasite consomment activement et croissent sur substrat artificiel conventionnel et le développement larvaire est complet sur différents régimes de compositions variables. Cependant, à la suite de l'élimination du méconium, la plupart des individus meurent en prénymphes. Quelques nymphes sont obtenues mais aucun adulte n'émerge. La survie paraît liée à la teneur mesurable de proteïnes de la larve en développement; des facteurs pouvant influer sur le développement ultérieurs sont discutés.
Amniotic fluid volumes in pregnant diabetics during the last trimester. A comparative study using ultrasound and PAH dilution. (1982)

Amniotic fluid was measured by ultrasound and PAH dilution technique in 15 insulin-dependent diabetics during the last trimester of pregnancy. Total uterine volume and fetal volume were estimated by ultrasound. The amniotic fluid volume was obtained by subtracting fetal volume and approximated values for placental volume obtained from the literature from the total uterine volume. The mean amniotic fluid volume determined by ultrasound was 1261 ml (range 278-3563). The mean amniotic fluid volume determined by PAH dilution was 1264 ml (range 344-3852). The values for amniotic fluid determined by these two methods were closely correlated (r = 0.96).
Access as a means of configuring cooperative interfaces (1993)

The emergence of CSCW has seen the development of a number of applications which simultaneously present a number of interfaces to a community of users. Limited consideration has been given to the provision of facilities that support the configuration and tailoring of these cooperative user interfaces.
Design of a monochromatizing wedge decelerator for therapeutic positron emitting light ion beams (2011)

Design of a monochromatizing wedge decelerator for therapeutic positron emitting light ion beams
Das Vokalsystem (1972)

Das dt. Phonemsystem erlaubt es, einigermaßen klar zwischen Vokalen und Konsonanten zu unterscheiden als zwei Mengen, die sich gegenseitig ausschließen.
A foreground biased depth map refinement method for DIBR view synthesis (2012)

The performance of view synthesis using depth image based rendering (DIBR) highly depends on the accuracy of depth map. Inaccurate boundary alignment between texture image and depth map especially for large depth discontinuities always cause annoying artifacts in disocclusion regions of the synthesized view. Pre-filtering approach and reliability-based approach have been proposed to tackle this problem. However, pre-filtering approach blurs the depth map with drawback of degradation of the depth map and may also cause distortion in non-hole region. Reliability-based approach uses reliable warping information from other views to fill up holes and is not suitable for the view synthesis with single texture video such as video-plus-depth based DIBR applications. This paper presents a simple and efficient depth map preprocessing method with use of texture edge information to refine depth pixels around the large depth discontinuities. The refined depth map can make the whole texture edge pixels assigned with foreground depth values. It can significantly improve the quality of the synthesized view by avoiding incorrect use of foreground texture information in hole filling. The experimental results show the proposed method achieves superior performance for view synthesis by DIBR especially for large baseline.
Evaluation and Extension of the Flutter-Margin Method for Flight Flutter Prediction (1993)

For a binary flutter the so-called flutter-margin method is a good way of extrapolating from subcritical flight test data to estimate the flutter speed; the best estimates are obtained with a linear extrapolation. Good estimates of the flutter speed can be obtained from data at speeds as low as 50% of the flutter speed. The flutter-margin is*shown to be relatively insensitive to errors in the damping measurements, but is very sensitive to errors in frequency measurements. It does not give good predictions of the flutter speed when the instability is dominated by a single degree-of-freedom mechanism. A new form of flutter-margin has been developed for a trinary flutter, which also varies in a sensibly linear manner with dynamic pressure; it is also relatively insensitive to errors in damping, but is very sensitive to errors in frequency.
Low-Intensity Extracorporeal Shock Wave Therapy Promotes Bladder Regeneration and Improves Overactive Bladder Induced by Ovarian Hormone Deficiency from Rat Animal Model to Human Clinical Trial (2021)

Postmenopausal women with ovary hormone deficiency (OHD) are subject to overactive bladder (OAB) symptoms. The present study attempted to elucidate whether low-intensity extracorporeal shock wave therapy (LiESWT) alters bladder angiogenesis, decreases inflammatory response, and ameliorates bladder hyperactivity to influence bladder function in OHD-induced OAB in human clinical trial and rat model. The ovariectomized (OVX) for 12 months Sprague-Dawley rat model mimicking the physiological condition of menopause was utilized to induce OAB and assess the potential therapeutic mechanism of LiESWT (0.12 mJ/mm<sup>2</sup>, 300 pulses, and 3 pulses/second). The randomized, single-blinded clinical trial was enrolled 58 participants to investigate the therapeutic efficacy of LiESWT (0.25 mJ/mm<sup>2</sup>, 3000 pulses, 3 pulses/second) on postmenopausal women with OAB. The results revealed that 8 weeks' LiESWT inhibited interstitial fibrosis, promoted cell proliferation, enhanced angiogenesis protein expression, and elevated the protein phosphorylation of ErK1/2, P38, and Akt, leading to decreased urinary frequency, nocturia, urgency, urgency incontinence, and post-voided residual urine volume, but increased voided urine volume and the maximal flow rate of postmenopausal participants. In conclusion, LiESWT attenuated inflammatory responses, increased angiogenesis, and promoted proliferation and differentiation, thereby improved OAB symptoms, thereafter promoting social activity and the quality of life of postmenopausal participants.
Mechanisms of blood pressure reduction by prolonged activation of the baroreflex (2009)

Recent technological advances have made the activation of the afferent limb of the baroreflex a viable therapeutic approach for lowering blood pressure. Experimental studies demonstrate sustained reductions in blood pressure in response to electrical baroreflex activation and initial results from clinical trials using device-based therapy for drug-resistant hypertension are promising. Although theoretically obvious at first glance, the mechanisms involved in the blood pressure lowering effect of baroreflex activation elude precise quantification, and experiments designed to investigate them invariably challenge preconceived notions and even dogmas. This paper is a brief overview of our current understanding of these mechanisms.
Mast Cell Function (2014)

Since first described by Paul Ehrlich in 1878, mast cells have been mostly viewed as effectors of allergy. It has been only in the past two decades that mast cells have gained recognition for their involvement in other physiological and pathological processes. Mast cells have a widespread distribution and are found predominantly at the interface between the host and the external environment. Mast cell maturation, phenotype and function are a direct consequence of the local microenvironment and have a marked influence on their ability to specifically recognize and respond to various stimuli through the release of an array of biologically active mediators. These features enable mast cells to act as both first responders in harmful situations as well as to respond to changes in their environment by communicating with a variety of other cells implicated in physiological and immunological responses. Therefore, the critical role of mast cells in both innate and adaptive immunity, including immune tolerance, has gained increased prominence. Conversely, mast cell dysfunction has pointed to these cells as the main offenders in several chronic allergic/inflammatory disorders, cancer and autoimmune diseases. This review summarizes the current knowledge of mast cell function in both normal and pathological conditions with regards to their regulation, phenotype and role.