gebhart/patrepeval huggingface dataset:
Incorporation of 4′-C-aminomethyl-2′-O-methylthymidine into DNA by thermophilic DNA polymerases (2012)

The dual modified nucleotide 4'-C-aminomethyl-2'-O-methylthymidine 5'-triphosphate was synthesized and enzymatically incorporated into DNA by the thermophilic DNA polymerases Pfu and Therminator III. The dual ribose modification imparted increased exonuclease resistance to DNA compared to the well-known 2'-O-methyl modification.
Molecular cloning of a possible excretion protein of<i>Vibrio cholerae</i> (1985)

The gene for a Vibrio cholerae protein of about kDa (kilodalton) has been cloned and its location within the 1.9-kb cloned DNA fragment determined by transposon insertion and deletion analyses. The proteins encoded within the various plasmids have been analyzed in Escherichia coli K-12 minicells. The 25-kDa protein when expressed in E. coli K-12 allows the release of the periplasmic deoxyribonuclease. It is a minor protein suggesting that the release of DNase is not an artefact due to membrane damage. It is possible that this protein functions as part of an excretion system. Results with transposon Tn1725 insertions suggest that it contains a termination site in one orientation and a promoter in the other.
A long uniform taper applied to an all-fiber Tm3+ doped double-clad fiber laser (2010)

A long uniform taper fabricated on a large mode area Tm3+-doped double-clad fiber laser, which was clad-pumped by a laser diode (LD), was found to be an effective wavelength filter while improving the output beam quality and narrowing the line-width significantly. The long uniform taper was fabricated directly on the multi-mode Tm3+-doped fiber by heating and stretching method, and located several centimeters before the output fiber end. By slightly bending the taper section, the output laser spectrum was left with only one peak with a line-width less than 0.5 nm, compared to the multi-peak spectrum with a 5 nm line-width before tapering, indicating that the multi-mode fiber could produce quasi-single wavelength output with a long uniform taper. The beam quality factor M 2 declined from 6.6 to 2.6 compared. Only a slight decrease in slope efficiency, from 19.2 to 17.5%, was observed. The main output wavelength had a blue shift of 8 nm.
Transcranial Doppler: An Overview of its Clinical Applications (2000)

Routine transcranial Doppler (TCD) ultrasound examination of the intracranial arteries was demonstrated to be possible in 1982. One fact that has to be constantly kept in mind when utilizing TCD is that the value obtained for a particular artery is the velocity of blood flowing through the vessel, and unless the diameter of that vessel is established by some other means it is not possible to determine the actual blood flow. Thus TCD is primarily a technique for measuring relative changes in flow. The utility of the technique is now well established for a number of different disease processes.
Mode mixing in fiber optic oximeter (1990)

Most catheter based oximeters use optical fiber to deliver two M more colors of light to the blood and collect the reflected lights with another optical fiber. Oxygen saturation of the blood is calculated from intensity of the returned lights. The coupling efficiency of this type of two-fiber sensor depends on the separation of fibers, the numerical aperture (NA) of the fibers, and the launching condition of lights from LED's to the transmission fiber. A micro-optical integrator was designed to combine outputs from two LED's into a multimode step-index fiber pig-tail through a high NA microball lens. The mismatch in the modes of propagation between red and IR lights was corrected by looping and sine-wave bending the fiber before it was coupled to an NA limiting GRIN lens, which also serves as an exit window. A far-field scan of two lights shows these two lights have spatial overlap of 92% or better. The overlap at the tip of the catheter, after it was coupled to the mode mixing pig-tail, is better than 98%. The addition of this simple method of mode-mixing has improved the overlap by nearly 30% and has substantially improved the accuracy of the oximeter, especially when in vitro calibration is used before taking the measurement in blood.
A Nonlinear Model Predictive Control scheme for cooperative manipulation with singularity and collision avoidance (2017)

This paper addresses the problem of cooperative transportation of an object rigidly grasped by N robotic agents. In particular, we propose a Nonlinear Model Predictive Control (NMPC) scheme that guarantees the navigation of the object to a desired pose in a bounded workspace with obstacles, while complying with certain input saturations of the agents. Moreover, the proposed methodology ensures that the agents do not collide with each other or with the workspace obstacles as well as that they do not pass through singular configurations. The feasibility and convergence analysis of the NMPC are explicitly provided. Finally, simulation results illustrate the validity and efficiency of the proposed method.
Ocular Complication of PhotoDerm VL Therapy for Facial Port-Wine Stain (2003)

BACKGROUND A case of focal damage to the iris with distortion of the pupil secondary to PhotoDerm therapy in a 2-year-old boy is reported. OBJECTIVE To study ocular complication of photoDerm VL therapy for facial port-wine stain. METHODS Observatory case report. RESULTS PhotoDerm VL therapy may damage ocular tissues. CONCLUSION Appropriate protection during the procedure is essential.
Tissue‐engineered skin substitutes: from <i>in vitro</i> constructs to <i>in vivo</i> applications (2004)

The field of skin tissue engineering is a paradigm for the various efforts towards the reconstruction of other tissues and organ substitutes. As skin replacement, this biotechnological approach has evolved from simple cultured autologous epidermal sheets to more complex bilayered cutaneous substitutes. The various types of such substitutes are herein presented with their intended use. However, two integrative characteristics are analysed more specifically because of their critical role: neovascularization and re-innervation. Furthermore, the in vitro use of these various skin substitutes has shed light on various physiological and pathological phenomena. Thus, not only the in vivo application of these skin substitutes as grafts, but also their in vitro value as skin models, are presented.
Flank or belly nosing in weaned pigs (2001)

Objective: To examine growth rate of pigs that engaged in, or were the recipients of, flank or belly nosing. Methods: Data was collected from 332 weaned pigs during a 6-week period after they were weaned at 16 to 18 days of age. Sixteen pens of pigs were observed for nosing activity during the first 16 days postweaning, and associated skin lesions and growth rate throughout the entire 6 weeks in the nursery were recorded. Results: Nosing activity was not observed until 3 days postweaning and peaked in number of pigs involved and duration of activity about 1 week after weaning. Nearly half of all pigs were observed performing some flank- or belly-nosing activity. Pigs that nosed were more likely to become the smallest pigs, although initial weight did not differ between pigs that nosed and those that didn’t. In this study, sexes were housed separately, and no difference between gilts and barrows was detected in amount of nosing activity, measured either by number of days observed nosing or total seconds observed nosing. However, barrows had more skin lesions caused by nosing than did gilts. Implications: Although flank or belly nosing is esthetically annoying to animal caretakers, it did not slow the growth rate of recipients. However, there was confounding of effect, since the most rapidly growing pigs were the most attractive targets for the perpetrators. While being a recipient of belly nosing did not affect growth, being a perpetrator was strongly associated with a reduction in growth rate.
Non-intrusive object introspection in C++: architecture and application (1998)

We describe the design and implementation of system architecture to support object introspection in C++. In this system, information is collected by parsing class declarations, and used to build a supporting environment for object introspection. Our approach is nonintrusive because it requires no change to the original class declarations and libraries, and it guarantees compatibility between objects before and after the addition of introspective capability. This is critical if one wants to integrate third-party class libraries, which are often supplied as black boxes and allow no modification, into highly dynamic applications. We show two applications: automatic I/O support for C++ objects; and an interactive exercise of dynamically loaded C++ class libraries.
Real-time motion estimation based on event-based vision sensor (2014)

Fast and efficient motion estimation is essential for a number of applications including the gesture-based user interface (UI) for portable devices like smart phones. In this paper, we propose a highly efficient method that can estimate four degree of freedom (DOF) motional components of a moving object based on an event-based vision sensor, the dynamic vision sensor (DVS). The proposed method finds informative events occurred at edges and estimates their velocities for global motion analysis. We will also describe a novel method to correct the aperture problem in the motion estimation.
Focus and accent in a Dutch text-to-speech system (1989)

In this paper we discuss an algorithm for the assignment of pitch accent positions in text-to-speech conversion. The algorithm is closely modeled on current linguistic accounts of accent placement, and assumes a surface syntactic analysis of the input. It comprises a small number of heuristic rules for determining which phrases of a sentence are to be focussed upon; the exact location of a pitch accent within a focussed phrase is determined mainly on the basis of the syntactic relations holding between the elements of the phrase. A perceptual evaluation experiment showed that the algorithm proposed here leads to improved subjective speech quality as compared to a naive algorithm which accents all and only content words.
Safety and immunological responses to human mesenchymal stem cell therapy in difficult-to-treat HIV-1-infected patients (2013)

umbilical cord-MSC transfusions are well tolerated and can efficiently improve host immune reconstitution in INRs, suggesting that such treatments may be used as a novel immunotherapeutic approach to reversing immune deficiency in HIV-1-infected INRs (ClinicalTrials.gov identifier: NCT01213186).
Study report on Northeast Asian labor force resource (2002)

With the constant development of the economic globalization and grouping of the regional economy, with the development of liberalization of investment and trade, the reasonable development and utilization of the labor force will be further developed among countries and regions. Especially in the era of knowledge economy, as the carrier of knowledge and source of knowledge innovation, human resources have already become the most important force in economic development and have received more and more attention from all countries. In Northeast Asia, the economic development level of various countries has enormous differences. Along with the development of investment, trade and exploration of resources, the complementary advantage of labor resource is turning into realistic economic development power progressively. The development and utilization of the labor force is becoming an important field of international cooperation. This report probes into the state of the Northeast Asian regional labor force resource, current obstacle; in the development and utilization of the labor force resource, and the future regional cooperation mode of the labor force resource in Northeast Asia.
A high CMRR, high resolution bio-ASIC for ECG signals (2016)

A High CMRR, High-resolution signal processing bio-ASIC circuit for wireless and wearable systems is presented. The chip consists of High CMRR Instrumentation Amplifier (IA) integrated with high accuracy pipeline ADC. The bio-ASIC front-end is built using current balance IA circuit followed by high pass and low pass filters. A High resolution, wide dynamic range, integrated Pipeline ADC allows input swing of ±1V. The ASIC is fabricated in 0.13μm CMOS process technology. The measured CMRR and integrated input referred noise of the circuit is 176dB at 150Hz and 4.5μν over the bandwidth of 0.1-150Hz. The Input Common Mode Range (ICMR) is 0-1.65V and the dynamic range is ±5mV. The ADC offers ENOB of 12.8 at 6 MSPS sampling speed & ± 0.75LSB of differential nonlinearity. The power consumption of the Instrumentation amplifier circuit is 33μW with a 3.3V supply.
Organic acids from fresh California strawberries (1975)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTOrganic acids from fresh California strawberriesCynthia J. Mussinan and John P. WalradtCite this: J. Agric. Food Chem. 1975, 23, 3, 482–484Publication Date (Print):May 1, 1975Publication History Published online1 May 2002Published inissue 1 May 1975https://pubs.acs.org/doi/10.1021/jf60199a018https://doi.org/10.1021/jf60199a018research-articleACS PublicationsRequest reuse permissionsArticle Views146Altmetric-Citations13LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
ITERATION-FREE FRACTAL CODING FOR IMAGE COMPRESSION USING GENETIC ALGORITHM (2008)

An iteration-free fractal coding for image compression is proposed using genetic algorithm (GA) with elitist model. The proposed methodology reduces the coding process time by minimizing intensive computations. The proposed technique utilizes the GA, which greatly decreases the search space for finding the self-similarities in the given image. The performance of the proposed method is compared with the iteration-free fractal-based image coding using vector quantization method for both single block and Quad tree partition on benchmark images for parameters such as image quality and coding time. It is observed that the proposed method achieves excellent performance in image quality with reduction in computing time.
An improved search algorithm using incremental knowledge for continuous speech recognition (1993)

A search algorithm that incrementally makes effective use of detailed sources of knowledge is proposed. The algorithm incrementally applies all available acoustic and linguistic information in three search phases. Phase one is a left-to-right Viterbi beam search that produces word end times and scores using right context between-word models with a bigram language model. Phase two, guided by results from phase one, is a right-to-left Viterbi beam search that produces word begin times and scores based on left context between-word models. Phase three is an A* search that combines the results of phases one and two with a long-distance language model. The objective is to maximize the recognition accuracy with a minimal increase in computational cost. With the decomposed, incremental, search algorithm, it is shown that early use of detailed acoustic models can significantly reduce the recognition error rate with a negligible increase in computational cost. It is demonstrated that the early use of detailed knowledge can improve the word error bound by at least 22% for large-vocabulary, speaker-independent, continuous speech recognition.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Maize developmental mutants (1982)

Among a large collection of maize defective kernel mutants 14 were identified that have embryos lacking leaf primordia at maturity. These are a type of developmental mutant; all are single-gene recessive mutants in which both the endosperm and the embryo are defective and all are lethal because their mature kernels fail to germinate. Five of the mutants are ailelic and located on chromosome arm is, while four other mutants are located on 1L, 3L, 4L, and 5L. The five allelic mutants are blocked at the proembryo stage, two other mutants are blocked at the transition stage, four at points intermediate between the transition and the coleoptilar stages, and one at the coleoptilar stage of embryo development. The other two developmental mutants produce embryos that range from the transition to the coleoptilar stage at maturity. One additional defective kernel mutant ranges from the coieoptilar stage to stage 1 (first leaf primordium) and two other mutants reach stage 1 or later by maturity. Endosperm-embryo interaction of 11 defective kernel mutants, Including nine developmental mutants (five are allelic), was examined by observing embryo development and germination capacity of mature kernels containing genetically normal endosperm and genetically mutant embryos as well as kernels containing the reciprocai arrangement. In all cases a normal endosperm failed to rescue a mutant embryo. When the endosperm was mutant and the embryo was normal, in all cases the embryos formed primordia and germinated; in eight cases (including five that are alleiic) more or less normal seedlings were produced, in one case the seedlings were weak, and in two cases the seedlings were lethal. It appears that for these mutants it is the genotype of the embryo that determines its developmental fate and its capacity to germinate but that a mutant endosperm can, in some instances, impair seedling growth. The developmental mutants offer promise for studying the genetic regulation of plant embryo development.
The Comparison Of High-intensity Interval Exercise Vs. Continuous Moderate-intensity Exercise On C1q/tnf-related Protein-9 Expression And Flow-mediated Vasodilation In Obese Individuals (2018)

PURPOSE: A recent novel adipocytokine, C1q/TNF-related protein-9 (CTRP9), has been shown to increase activation of endothelial nitric oxide synthase and reduce vasoconstrictors (e.g., endothelin-1). In addition, CTRP9 may play a compensatory role in obesity-related endothelial dysfunction. Although there is limited information regarding exercise-mediated CTRP9, high-intensity interval exercise (HIIE) has been shown to be as or more effective than continuous moderate-intensity exercise (CME) in improving indicators of endothelial function (e.g., brachial artery flow-mediated dilation [BAFMD]). Therefore, the purpose of this study was to investigate the effect of acute HIIE vs. CME on serum CTRP9 and BAFMD responses in obese individuals. METHODS: Sixteen young male subjects (9 obese and 7 normal-weight) participated in a counterbalanced and caloric equated experiment: HIIE (30 minutes, 4 intervals of 4 minutes at 80-90% of VO2max with 3 minutes rest between intervals) and CME (38 minutes at 50-60% VO2max). Serum CTRP9 and BAFMD, were measured prior to, immediately following exercise, and 1 hour and 2 hours into recovery. RESULTS: The concentration of serum CTRP9 was significantly increased immediately following acute HIIE and CME in both obese and normal-weight groups (p = 0.003). Furthermore, both significant treatment by time and group by time interactions for BAFMD were observed following both exercise protocols (p = 0.018; p = 0.009; respectively), with a greater CME-induced BAFMD response at 2 hours into recovery in obese compared to normal-weight subjects. Additionally, a positive correlation in percent change (baseline to peak value) between CTRP9 and BAFMD was found following acute CME (r = 0.589, p = 0.016). CONCLUSIONS: Acute HIIE is as effective as CME to upregulate CTRP9 expression in both obese and normal-weight individuals, although CTRP9 may potentially improve CME-mediated BAFMD. The novel results from this study provide a foundation for additional examination of the mechanisms of exercise-mediated CTRP9 on endothelial function.
De novo nonreciprocal translocation 1;8 confirmed by fluorescent in situ hybridization (1995)

Constitutional nonreciprocal translocations are extremely rare, and even their existence is controversial. We report on a newborn infant with a de novo nonreciprocal translocation between chromosomes 1 and 8 resulting in 1q42.3 deletion syndrome. Fluorescent in situ hybridization with whole chromosome paints confirmed the conventional cytogenetic diagnosis.
Wireless interrogation of antenna sensor to detect hidden cracks (2012)

Recently, we have validated that microstrip antenna can detect sub-millimeter crack growth. The wireless interrogation of the antenna sensor under line-of-sight illumination of an interrogation antenna has also been demonstrated. In this paper, we present a wireless interrogation technique that is out of the line-of-sight of the interrogation antenna. This technique enables detecting and monitoring crack propagation between a lap joint or in any other case where a crack is hidden between two parts of a structure. Implementation of the sensor and the wireless interrogation unit using commercially available microwave components is presented in detail. The experimental results confirmed the capability of this technique to wirelessly interrogate the antenna sensor. In addition to crack propagation detection, this technique can also be used to monitor compressive forces between two faying surfaces of a lap joint structure.
NPH4, a Conditional Modulator of Auxin-Dependent Differential Growth Responses in Arabidopsis (1998)

Although sessile in nature, plants are able to use a number of mechanisms to modify their morphology in response to changing environmental conditions. Differential growth is one such mechanism. Despite its importance in plant development, little is known about the molecular events regulating the establishment of differential growth. Here we report analyses of the nph4 (nonphototropic hypocotyl) mutants of Arabidopsis that suggest that the NPH4 protein plays a central role in the modulation of auxin-dependent differential growth. Results from physiological studies demonstrate that NPH4 activity is conditionally required for a number of differential growth responses, including phototropism, gravitropism, phytochrome-dependent hypocotyl curvature, apical hook maintenance, and abaxial/adaxial leaf-blade expansion. The nph4 mutants exhibited auxin resistance and severely impaired auxin-dependent gene expression, indicating that the defects associated with differential growth likely arise because of altered auxin responsiveness. Moreover, the auxin signaling events mediating phototropism are genetically correlated with the abundance of the NPH4 protein.
Prognostic Indicators of Unilateral Vocal Fold Paralysis (2008)

This study confirms that LEMG is a clinically useful tool that can offer prognostic information for UVFP especially if it is done at least 2 months after symptom onset.