gebhart/patrepeval huggingface dataset:
A Closed-Loop System for Examining Psychophysiological Measures for Adaptive Task Allocation (2000)

A closed-loop system was evaluated for its efficacy in using psychophysiological indexes to moderate workload. Participants were asked to perform either 1 or 3 tasks from the Multiattribute Task Battery and complete the NASA Task Load Index after each trial. An electroencephalogram (EEG) was sampled continuously while they performed the tasks, and an EEG index (beta/alpha plus theta) was derived. The system made allocation decisions as a function of the level of operator engagement based on the value of the EEG index. The results of the study demonstrated that it was possible to moderate an operator's level of engagement through a closed-loop system driven by the operator's own EEG. In addition, the system had a significant impact on behavioral, subjective, and psychophysiological correlates of workload as task load increased. The theoretical and practical implications of these results for adaptive automation are discussed.
Electromagnetic Design of a Superconducting Twin Axis Cavity (2017)

The twin-axis cavity is a new kind of rf superconducting cavity that consists of two parallel beam pipes, which can accelerate or decelerate two spatially separated beams in the same cavity. This configuration is particularly effective for high-current beams with low-energy electrons that will be used for bunched beam cooling of high-energy protons or ions. The new cavity geometry was designed to create a uniform accelerating or decelerating fields for both beams by utilizing a TM110 dipole mode. This paper presents the design rf optimization of a 1497 MHz twin-axis single-cell cavity, which is currently under fabrication.
Generation of flat-top focussed beams for percussion drilling of ceramic and metal (2002)

In most laser micro-machining applications using copper vapour lasers, the system is configured for near-diffraction limited beam quality. This enables the beam to be tightly focussed to very small spot sizes and can be used for drilling very small holes or trepanning larger ones. The focused spot has a gaussian-like profile. In this paper a new laser system is presented that has a flat-top beam when focused. This has many advantages over gaussian beams when applied to percussion drilling and certain other applications. This system has demonstrated high speed percussion drilling of high quality 100 micron diameter holes in metals. We also report high speed (&gt;200 holes/sec) percussion drilling in green sheet ceramic. The new laser system is a compact copper vapour laser (CVL) master-oscillator power-amplifier (MOPA) incorporating telescopic beam expansion in a high-gain double-pass amplifier. By configuring an oscillator for low coherence output and using a multimode optical fibre between the oscillator and a double-pass amplifier, high power (up to 34W) low divergence output beams having well defined flat-top far field beam profiles have been produced. This scheme generates a flat-top far-field beam profile by control of the spatial coherence of a flat-top near-field beam rather than the usual techniques of producing flattened gaussian beams from coherent gaussian beams. The output of such a MOPA has also demonstrated high power (34W average power, 80kW peak power) damage-free transmission through 100 micron core diameter optical fibres. This is of significant interest to system integrators and for certain applications.
Numerical Investigation for Net Enhancement in Thermal-Hydraulic Performance of Compact Fin-Tube Heat Exchangers with Vortex Generators (2008)

Systematic numerical simulations are carried out for a steady-state, laminar and constant-property air flow through a passage of a compact fin-tube heat exchanger specified with a constant wall temperature distribution and a uniform inlet velocity profile. A pair of delta winglet-type vortex generators (VGs) is punched out of the plain fin surface near the tube as a heat transfer enhancement device. A variety of VG configurations are investigated and their effects on the thermal-hydraulic (heat transfer) performance of the compact fin-tube heat exchanger are presented in terms of the Colburn factor j and the friction factor f for a specific Reynolds number (Re=400). In addition, the highest net enhancement in the thermal-hydraulic performance, defined as the ratio of the heat transfer enhancement to the pressure loss penalty, is sought. It is found that a moderate degree of the upstream shifting and the spanwise shifting of VG toward the tube contribute to the net enhancement. Nearly 9% of the net enhancement is achieved with an optimum configuration investigated presently.
Using a visible BI to construct lean manufacturing within big data (2015)

There are several factors to influence effectiveness of manufacturing. People productivity is one of very important factor that helps to construct lean manufacturing that provides profit of company. We separate operators' work hour into effective productivity and non-effective productivity to point out opportunity to improve productivity without heavy invest. Through constructed visible people loading with BI (Business Intelligent) software analysis system using existing KPI (Key performance Index), we can see whole picture of actual factory runs. Benchmark, resource leverage and re-organize job become possible and precise by visible chart within those huge data. Several truly opportunities and effective activities will be discussed as below that exposure by visible BI; most of them was executed and help us to improve at least 30% people productivity without extra heavy invest.
Upregulation of renin-angiotensin system and downregulation of kallikrein in obstructive nephropathy (1993)

The purpose of this study was to delineate the effects of prolonged (1 and 5 wk) unilateral ureteral obstruction (UUO) on the intrarenal renin-angiotensin and kallikrein-kinin systems in the rat. Systolic blood pressure (SBP) and plasma angiotensin (ANG) II levels were significantly higher at 1 and 5 wk of obstruction than in sham-operated groups. Also, plasma renin activity and ANG I levels were elevated at 1 wk (P < 0.05), and plasma angiotensin-converting enzyme (ACE)-kininase II activity was elevated at 5 wk (P < 0.05). Blockade of ANG II receptors with losartan (Dup 753) prevented the rise in SBP after UUO and normalized SBP in chronically hypertensive UUO rats. Renin mRNA levels and ANG II content were elevated in the obstructed kidneys at 1 and 5 wk compared with sham-operated kidneys (P < 0.05). ACE-kininase II activity was elevated in both the obstructed and contralateral kidneys at 5 wk compared with sham-operated kidneys (P < 0.05). In marked contrast to renin, total immunoreactive kallikrein contents and tissue kallikrein mRNA levels in the obstructed kidneys were reduced to 25% of sham-operated kidneys both at 1 and 5 wk (P < 0.001). The results indicate that urinary obstruction activates renin and suppresses kallikrein gene expression. Activation of ACE-kininase II by UUO also serves to enhance intrarenal ANG II generation and kinin degradation. The results implicate ANG II overproduction and kinin deficiency in the pathogenesis of UUO-induced hypertension and intrarenal vasoconstriction.
Essential Aspects of Space Suit Operating Pressure Trade-Off (1994)

<div class="htmlview paragraph">The operating pressure value is one of the principal considerations for trade-off analysis of the space suit enclosure and the individual life support subsystem (LSS). From the physiological point of view, the same level of pressure in the suit and space vehicle reflects the best solution. Current Russian space vehicles and orbiting stations use the “Earth atmosphere”. A suit operating pressure at such a level would result in complicated and technically unreasonable designs. Improved mobility of the pressurized suit and enhanced performance characteristics of the LSS can be offered with the minimized positive pressure.</div> <div class="htmlview paragraph">However, the minimized suit pressure concept leads to the increased risk of crewmember decompression sickness. Therefore, the suit operating pressure selection calls for a trade-off of physiological tolerances of the crewmember versus technical feasibility of this or that solution as principal considerations.</div> <div class="htmlview paragraph">The paper reviews the effect of the suit operating pressure on certain technical characteristics of a space suit, in particular, mobility, amount of oxygen available to compensate for leakage, mass and strength as well as on metabolic rate. The paper reviews also physiological criteria which affect the selection of the suit operating pressure. Based on the presented information, recommendations are given as to the trade selection of the suit operating pressure.</div>
Apoptosis and Angiotensin II: Yet Another Renal Regulatory System? (2001)

Apoptosis plays a key role in the regulation of normal renal structure and kidney remodeling in various renal diseases. Angiotensin II plays a prominent role in renal injury through its receptor subtypes, the type 1 (AT1) receptor and the type 2 (AT2) receptor, which involve different molecular mechanisms. In addition to its haemodynamic actions, angiotensin II induces apoptosis. Angiotensin II also increases proliferation in the kidney. A close correlation between renal cell proliferation and apoptosis has been shown in renal diseases as well as in the angiotensin II infusion model. Angiotensin induces upregulation of p53 and other pro-apoptotic proteins. Recent studies suggest that both AT1 and AT2 receptors influence the apoptotic process in the kidney. These apoptotic effects of angiotensin II should be considered as representing another regulatory mechanism that may modulate the balance between cell growth and proliferation within the kidney.
TEMPERATURE RESPONSES TO MONOAMINES AND AN INHIBITOR OF MAO INJECTED INTO THE CEREBRAL VENTRICLES OF RATS (1967)

The effects on body temperature of noradrenaline, adrenaline and 5-hydroxytryptamine (5-HT), when injected into the cerebral ventricles vary in different species. For instance, the two catecholamines lower body temperature in cats, dogs and monkeys, raise it in rabbits and sheep, and have no effect on goats and oxen. On the other hand, 5-HT raises temperature in cats, dogs and monkeys, has a weak and inconsistent hypothermic effect in rabbits and sheep, and produces pronounced hypothermia in goats and oxen (von
Recovery of Anoikis in Src-Transformed Cells and Human Breast Carcinoma Cells by Restoration of the SIRPα1/SHP-2 Signaling System (2010)

Src kinase dysregulation contributes to cancer progression but mechanistic understanding for this contribution remains incomplete. Signal regulatory protein α1 (SIRPα1) is a tumor suppressor that is constitutively suppressed in v-Src-transformed cells, where restoration of SIRPα1 expression inhibits anchorage-independent growth. In this study, we investigated the role of the protein tyrosine phosphatase-2 (SHP-2) in SIRPα1 activity. SHP-2 suppression resulted in a blockade of SIRPα1-mediated inhibition of anchorage-independent growth. Notably, we found that SIRPα1 did not act in v-Src-transformed cells by triggering cell growth arrest but by eliciting a suspension-selective apoptosis (anoikis), and that SHP-2 was required for this effect. Furthermore, we found that SHP-2 was crucial for recovery of stress fiber and focal contact formation by SIRPα1 in v-Src-transformed cells. Finally, we found that SIRPα1/SHP-2 signaling regulates anoikis in human breast carcinoma cells with activated c-Src. Taken together, our findings define SHP-2 as an essential component of tumor suppression and anoikis mediated by SIRPα1 in human breast carcinoma cells as well as in v-Src-transformed cells.
Dynamic Equilibrium of a Supramolecular Dimeric Rhomboid and Trimeric Hexagon and Determination of Its Thermodynamic Constants (2003)

A supramolecular dimeric rhomboid and its trimeric counterpart, a hexagon, are generated by design via the directional bonding methodology of self-assembly. The different-sized supramolecular macrocycles formed by Pt-coordination undergo a concentration- and temperature-dependent dynamic equilibrium. The two structures are characterized by multinuclear NMR and ESI-MS. Extensive study of the dynamic equilibrium of the two species in solution is performed to obtain its thermodynamic properties. By varying the ionic strength, mu, of the solutions, the true thermodynamic equilibrium constant, K, is determined at each experimental temperature (K(253) = 36 +/- 7, K(273) = 18 +/- 6, K(293) = 10 +/- 3, K(313) = 9 +/- 2, K(333) = 5 +/- 2, and K(353) = 3.0 +/- 0.2). By applying these values of true K at the respective temperatures to the van't Hoff equation extended with the entropy term, the standard enthalpy and entropy changes are determined for the equilibrium: with Delta H degrees = -18 +/- 1 kJ mol(-1) and Delta S degrees = -43 +/- 4 J mol(-1) K(-1), respectively, for the forward reaction (rhomboid to hexagon) of the equilibrium. The rhomboid is selectively crystallized, and its crystal structure is determined by X-ray diffraction. The structure reveals a significant amount of porosity as well as distortion of the rhomboid from planarity, leading to channels that can be observed from two viewing positions of the packing.
Rapid precipitation in an Al<sub>0.5</sub>CrFeCoNiCu high entropy alloy (2015)

The effect of cooling rate on the microstructural evolution of Al 0.5 CrFeCoNiCu has been studied using differential scanning calorimetry and scanning electron microscopy. As cast Al 0.5 CrFeCoNiCu contained three phases; Cr–Fe–Co–Ni solid solution dendrites, Cu rich interdendritic material and L1 2 precipitates. During cooling at rates between 10 and 50°C min −1 , an additional exothermic event, at ∼1010°C, was observed in the heat flow curves. Microstructural examination after cooling revealed the presence of two distinct populations of intragranular precipitates not present in the as cast material. Energy dispersive X-ray spectroscopy indicated that Cu rich precipitates formed within the dendrites, while a Cr–Fe–Co rich phase formed in the interdendritic constituent. Precipitation during cooling at rates approaching 1°C s −1 indicates that the diffusion kinetics of Al 0.5 CrFeCoNiCu is not, as previously suggested, sluggish.
Polycistronic transcripts in trypanosomes and their accumulation during heat shock: evidence for a precursor role in mRNA synthesis. (1988)

Maturation of mRNA precursors in trypanosomes involves an apparent trans splicing event in which a 39-nucleotide miniexon sequence, common to all trypanosome mRNAs, is joined to the 5' end of a protein-coding exon. We demonstrate that the processing machinery responsible for the maturation of tubulin mRNA precursors in Trypanosoma brucei can be disrupted by heat shock. This results in an accumulation of polycistronic RNA species and a decrease in the abundance of branched splicing intermediates. At normal temperatures, tubulin polycistronic transcripts were also detected and were shown in pulse-chase experiments to be abundantly synthesized and very rapidly turned over. These results, combined with results of the heat shock experiments, suggest that these polycistronic transcripts are the precursors of the (monocistronic) tubulin mRNAs of trypanosomes.
Effect of Intranasal Reovirus Infection on Antibacterial Activity of Mouse Lung (1969)

Journal Article Effect of Intranasal Reovirus Infection on Antibacterial Activity of Mouse Lung Get access Jerome O. Klein, Jerome O. Klein From the Thorndike Memorial and Channing Laboratories, Second and Fourth (Harvard) Medical and Pediatric Services, Boston City Hospital; and the Departments of Medicine and Pediatrics, Harvard Medical School, Boston, Massachusetts Search for other works by this author on: Oxford Academic PubMed Google Scholar Gareth M. Green, Gareth M. Green From the Thorndike Memorial and Channing Laboratories, Second and Fourth (Harvard) Medical and Pediatric Services, Boston City Hospital; and the Departments of Medicine and Pediatrics, Harvard Medical School, Boston, Massachusetts Search for other works by this author on: Oxford Academic PubMed Google Scholar Jeremiah G. Tilles, Jeremiah G. Tilles From the Thorndike Memorial and Channing Laboratories, Second and Fourth (Harvard) Medical and Pediatric Services, Boston City Hospital; and the Departments of Medicine and Pediatrics, Harvard Medical School, Boston, Massachusetts Search for other works by this author on: Oxford Academic PubMed Google Scholar Edward H. Kass, Edward H. Kass From the Thorndike Memorial and Channing Laboratories, Second and Fourth (Harvard) Medical and Pediatric Services, Boston City Hospital; and the Departments of Medicine and Pediatrics, Harvard Medical School, Boston, Massachusetts Search for other works by this author on: Oxford Academic PubMed Google Scholar Maxwell Finland Maxwell Finland From the Thorndike Memorial and Channing Laboratories, Second and Fourth (Harvard) Medical and Pediatric Services, Boston City Hospital; and the Departments of Medicine and Pediatrics, Harvard Medical School, Boston, Massachusetts Search for other works by this author on: Oxford Academic PubMed Google Scholar The Journal of Infectious Diseases, Volume 119, Issue 1, January 1969, Pages 43–50, https://doi.org/10.1093/infdis/119.1.43 Published: 01 January 1969 Article history Received: 09 July 1968 Published: 01 January 1969
Reactions of the Ion Pair [Os(NH3)6]3+.cntdot.[Fe(CN)6]3- (1995)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTReactions of the Ion Pair [Os(NH3)6]3+.cntdot.[Fe(CN)6]3-Vassiliki G. Poulopoulou and Henry TaubeCite this: Inorg. Chem. 1995, 34, 6, 1299–1301Publication Date (Print):March 1, 1995Publication History Published online1 May 2002Published inissue 1 March 1995https://pubs.acs.org/doi/10.1021/ic00110a001https://doi.org/10.1021/ic00110a001research-articleACS PublicationsRequest reuse permissionsArticle Views45Altmetric-Citations3LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Rara vez está indicada una conización de cérvix mediante LEEP para resolver discrepancias de dos niveles (2008)

Objetivo. Entre las indicaciones actuales para practicar conización de cérvix está la resolución de crepancias dos niveles entre los resultados citológicos e tológicos. tamos de determinar la utilidad de la conización iante asa con electrocauterio (LEEP) para resolver discrepancias dos niveles. Métodos. Se llevó a cabo una revisión rospectiva obada por el comité de ética de las historias iacute;nicas de as las mujeres a las que se había recomendado una LEEP s detectar discrepancias entre un resultado citológico de ión escamosa intraepitelial de alto grado que había ivado el envío de la paciente y un resultado histológico mal o de neoplasia cervical intraepitelial (CIN) 1 en una psia colposcópica posterior; los casos diagnosticados de 2 se excluyeron del estudio. Los análisis estadísticos se realizaron con el software SAS 9 (SAS Institute, Inc., Cary, NC). Los resultados se consideraron significativos con un valor de p igual o inferior a 0,05. Resultados. A 59 pacientes se les había practicado una LEEP para resolver discrepancias de dos niveles entre los resultados citológicos e histológicos. A 27 pacientes se les practicó una segunda exéresis con asa del endocervix o conización mediante LEEP. De las pacientes con un resultado normal en la biopsia de cérvix y un resultado citológico de alto grado,10 (29%) de 34 presentaban resultados histológicos normales, en la LEEP, y 14 (41%) de 34 presentaban CIN 3; 16 (64%) de 25 pacientes con un resultado citológico de alto grado y un resultado de CIN 1 en la biopsia presentaban CIN 3, según lo indicado en la LEEP. En comparación con las pacientes con un resultado normal en la biopsia inicial de cérvix, aquellas con un resultado de CIN 1 en la biopsia inicial tenían más probabilidades de tener un resultado de CIN 3 en la LEEP (p = 0,08). A 27 de 59 pacientes se les había practicado una conización mediante LEEP; una de 27 presentaba un resultado de CIN 3 en el segundo paso, endocervical, del asa. Este caso se asoció con una CIN 3 identificada en el primer paso, ectocervical, del asa con márgenes positivos. El segundo paso del asa endocervical en la conización mediante LEEP no permitió demostrar la presencia de CIN en el 96% de los casos (p < 0,0001). Las pacientes con un resultado normal o de CIN 1 en el primer paso del asa obtuvieron un resultado normal en el segundo paso en el 100% de los casos. Conclusiones. Rara vez está indicada una conización mediante LEEP para la evaluación de una discrepancia de dos niveles. En este sentido, está justificada la realización de un estudio aleatorizado para analizar esta cuestión. ▪
Caudal mediastinal node lymph flow in sheep after histamine or endotoxin infusions (1990)

To determine whether intrathoracic nonpulmonary structures (caudal mediastinal node or esophagus) are reputed to affect lung lymph dynamics, we studied anesthetized, open-thorax, prone, ventilated sheep in which all lung afferent lymphatics to the caudal mediastinal node were eliminated. When we increased left atrial pressure by 20 cmH2O in four sheep, there was no effect on caudal mediastinal node efferent lymph flow or protein concentration, thus providing the completeness of the surgical preparation. In four sheep, intravenous histamine infusions (3 micrograms base.kg-1.min-1) had no effect on caudal mediastinal node lymph flow or protein concentration. In seven sheep with intact lung lymphatics, Escherichia coli endotoxin infusion (1 microgram/kg over 20 min) increased lymph flow with high lymph protein concentration during the late phase (2-6 h). In seven sheep, after all lung lymphatic afferents had been cut, endotoxin did not affect caudal mediastinal node lymph flow, although lymph protein concentration was decreased in the early 0-2 h, "hypertensive") phase. We conclude that at the concentrations tested, which are those regularly used in sheep lung experiments, the effects of histamine and endotoxin on caudal mediastinal node lymph flow and protein concentration are limited to the lung.
Space storable propellant acquisition system (1974)

Surface tension propellant acquisition concepts for an advanced spacecraft propulsion system having a 10-year mission capability were investigated. Surface tension systems were specified because they were shown to be the best propellant acquisition technique for various interplanetery spacecraft in a prior study. A variety of surface tension concepts for accomplishing propellant acquisition were formulated for the baseline space storable propulsion module and Jupiter Orbiter mission. Analyses and evaluations were then conducted on each candidate concept to assess fabricability, performance capability, and spacecraft compatibility. A comparative evaluation of the results showed the Fruhof-class of low-g surface tension systems to be preferred for these interplanetary applications.