gebhart/patrepeval huggingface dataset:
High levels of factor IX increase the risk of venous thrombosis (2000)

Elevated plasma levels of factor VIII (> 150 IU/dL) are an important risk factor for deep vein thrombosis (DVT). Factor VIII is the cofactor of factor IXa in the activation of factor X. The risk of thrombosis in individuals with an elevated factor IX level is unknown. This study investigated the role of elevated factor IX levels in the development of DVT. We compared 426 patients with a first objectively diagnosed episode of DVT with 473 population controls. This study was part of a large population-based case-control study on risk factors for venous thrombosis, the Leiden Thrombophilia Study (LETS). Using the 90th percentile measured in control subjects (P(90) = 129 U/dL) as a cutoff point for factor IX levels, we found a 2- to 3-fold increased risk for individuals who have factor IX levels above 129 U/dL compared with individuals having factor IX levels below this cutoff point. This risk was not affected by adjustment for possible confounders (age, sex, oral contraceptive use, and high levels of factor VIII, XI, and vitamin K-dependent proteins). After exclusion of individuals with known genetic disorders, we still found an odds ratio (OR) of 2.5 (95% confidence interval [CI]: 1.6-3.9). The risk was higher in women (OR: 2.6, CI: 1.6-4.3) than in men (OR: 1.9, CI: 1.0-3.6) and appeared highest in the group of premenopausal women not using oral contraceptives (OR: 12.4, CI: 3.3-47.2). These results show that an elevated level of factor IX is a common risk factor for DVT. (Blood. 2000;95:3678-3682)
Some Pattern Recognition Challenges in Data-Intensive Astronomy (2006)

We review some of the recent developments and challenges posed by the data analysis in modern digital sky surveys, which are representative of the information-rich astronomy in the context of virtual observatory. Illustrative examples include the problems of an automated star-galaxy classification in complex and heterogeneous panoramic imaging data sets, and an automated, iterative, dynamical classification of transient events detected in synoptic sky surveys. These problems offer good opportunities for productive collaborations between astronomers and applied computer scientists and statisticians, and are representative of the kind of challenges now present in all data-intensive fields. We discuss briefly some emergent types of scalable scientific data analysis systems with a broad applicability
The Biosynthesis of a Disialylganglioside by Galactosyltransferase from Rat Brain Tissue (1972)

Abstract An enzymatic method for the preparation of ceramide-Glc-Gal(NeuAc)2-GalNAc (Gd2) from ceramide-Glc-Gal-(NeuAc)2-GalNAc-Gal (Gd1b) is described. Gd2, prepared in this manner, is an acceptor of galactose from UDP-Gal when incubated with a particulate subcellular fraction from rat brain to form Gd1b. This reaction was studied and compared with an analogous reaction for the synthesis of ceramide-Glc-Gal(NeuAc)-GalNAc-Gal (Gm1) using ceramide-Glc-Gal(NeuAc)-GalNAc (Gm2) as acceptor of galactose. The results obtained in this comparative study suggest that Gd2 is an intermediate in the pathway of synthesis of Gd1b. Furthermore, the transfer of galactose in the two reactions appears to be catalyzed by the same enzyme.
Abstract 73: Effect Of A Lifestyle Improvement Program Using Cardiac Rehabilitation Resources On Metabolic Syndrome Components (2012)

Objective We studied the effect of a lifestyle therapy program using the resources already available in a cardiac rehabilitation setting for patients at risk for metabolic syndrome (MetS). Methods We created a six-week cardiometabolic program (CMP) using facilities and resources of a cardiac rehabilitation setting. The CMP included a minimum of 6 once-a-week 60 min sessions consisting of exercise training and nutrition instruction, in addition to 6 once-a-week 60 min group behavioral modification classes following the LEARN program. We also assessed the outcomes in 239 patients (pts) who had at either obesity or hyperglycemia: 58 pts had enrolled and completed the CMP, 58 pts had signed up for the CMP but either never attended or dropped out early (Control 1) and had follow-up data, and 123 pts had not signed up for the CMP but had been seen in the outpatient preventive cardiology practice at the Mayo Clinic (Control 2). We compared changes in components of the MetS from baseline to six weeks (for the CMP group) and at 6 months for all pts. Results Of 187 people who signed up for the CMP, only 62 completed the program and from those, 58 gave authorization to use their clinical data in research. Of the 125 that never attended or dropped out early, 58 had follow-up data. Clinical characteristics of the CMP, Control 1, and Control 2 groups and improvement in each of the outcome measures are shown in the Table. In the CMP group, there was a significant improvement at 6 weeks in waist circumference, weight, diastolic blood pressure and total cholesterol. At 6 months the fasting glucose had also significantly improved. In contrast, improvements in Control 1 and Control 2 were modest at best. See Table. When comparing the 6 month changes in the CMP and Control 1, those in the CMP had more pronounced weight loss (-4.5±5 kg vs -0.14±6 kg, p<0.001); decrease in systolic blood pressure (-1.1±17 mmHg vs +9.6±20 mmHg, p=0.004); and decrease in diastolic blood pressure (-4.6±11 mmHg vs +3.4±15 mmHg, p=0.0017). Similarly, comparing CMP vs Control 2, a significantly greater drop in body weight (-4.5±5 kg vs -0.9±3 kg, p<0.001) and in diastolic blood pressure (-4.6±11 mmHg vs -0.7±9 mmHg, p=0.0202) was noted in the CMP. The change in the number of MetS components per patient dropped significantly, favoring the CMP group compared with the control groups. Conclusion A lifestyle therapy program for patients at risk for MetS can be implemented using existing resources of a cardiac rehabilitation program, although enrollment and completion rates are low. Such a program, however, is effective at improving cardiometabolic outcomes in individuals at risk for MetS.
Monte Carlo Simulation of Partially Confined Flexible Polymers (2002)

We have studied conformational properties of flexible polymers partially confined to narrow pores of different size using configurational biased Monte Carlo simulations under athermal conditions. The asphericity of the chain has been studied as a function of its center of mass position along the pore axis and as a function of the degree of penetration, or fraction of confined segments. The asphericity passes through a maximum well before all segments are located inside the pore. Rather than deforming gradually, we find that at intermediate penetration degrees, where the center of mass is within distances of approximately one radius of gyration away from the pore entry, the chain part inside the pore stretches out considerably while the remaining part outside the pore is coillike (“flower conformations”). When the center of mass is located further inside the pore, this strong chain extension along the pore axis diminishes, and the average conformation becomes that of a deformed coil. Introduction of weakly attractive monomer−wall interactions does not affect these observations significantly.
N-acetoxy-2-acetylaminofluorene induced unscheduled DNA synthesis of granulopoietic precursor cells in chronic myeloid leukemia (1980)

Studies on N-acetoxy-2-acetylaminofluorene (NA-AAF) induced unscheduled DNA synthesis (UDS) of granulopoietic cells were performed in patients with chronic myeloid leukemia (CML). Sequential studies were carried out in some patients. Both biochemical and autoradiographic methods demonstrated that [3H]dT was incorporated into nonreplicating DNA of immature granulopoietic cells after NA-AAF damage and the 2 methods significantly correlated to each other (r = 0.63, n = 19). NA-AAF induced DNA synthesis was lower for myeloblasts than promyelocytes and myelocytes. Biochemically determined NA-AAF induced UDS was higher for immature granulopoietic cells in blood than in marrow. Sequential studies on granulopoietic blood cells suggested that phases of accelerated leukocytosis in CML can be preceded by increases of NA-AAF induced UDS. Whether increases in NA-AAF induced UDS relates to an amplification of repair enzymatic capacity closely correlated to the cellular replication capacity, or whether it reflects an increased sensitivity to DNA damage induction and the consequences thereof, was not resolved in this study. Nevertheless these results are consistent with the hypothesis that increases in NA-AAF induced UDS signal the evolution during chronic phase CML of cell populations of increasing malignancy which escape growth control.
High Dose Integrating Chemical Dosimeters The radiolysis of aqueous sodium oxalate solutions. EUR 3914.1. (1968)

The radiolytic decomposition of aqueous 0.1 N, 0.2 N and 0.4 N sodium oxalate solutions was studied using 2 MV electrons from a van de Graafi accelerator.High dose rates (0.2 10 e rad/sec) were achieved and conversions of the starting material of higher than 99 % finally obtained.For the 0.4 solution a 0.5 reaction order was established for the oxalate decrease up to 300 IO 6 rad total absorption.Also for the 0.1 and 0.2 solutions the same reaction order was observed when irradiating up to 225 10 rad absorption.
Effects of Floral Scents and Their Dietary Experiences on the Feeding Preference in the Blowfly, Phormia regina (2015)

The flowers of different plant species have diverse scents with varied chemical compositions. Hence, every floral scent does not uniformly affect insect feeding preferences. The blowfly, Phormia regina, is a nectar feeder, and when a fly feeds on flower nectar, its olfactory organs, antennae, and maxillary palps are exposed to the scent. Generally, feeding preference is influenced by food flavor, which relies on both taste and odor. Therefore, the flies perceive the sweet taste of nectar and the particular scent of the flower simultaneously, and this olfactory information affects their feeding preference. Here, we show that the floral scents of 50 plant species have various effects on their sucrose feeding motivation, which was evaluated using the proboscis extension reflex (PER). Those floral scents were first categorized into three groups, based on their effects on the PER threshold sucrose concentration, which indicates whether a fly innately dislikes, ignores, or likes the target scent. Moreover, memory of olfactory experience with those floral scents during sugar feeding influenced the PER threshold. After feeding on sucrose solutions flavored with floral scents for 5 days, the scents did not consistently show the previously observed effects. Considering such empirical effects of scents on the PER threshold, we categorized the effects of the 50 tested floral scents on feeding preference into 16 of all possible 27 theoretical types. We then conducted the same experiments with flies whose antennae or maxillary palps were ablated prior to PER test in a fly group naïve to floral scents and prior to the olfactory experience during sugar feeding in the other fly group in order to test how these organs were involved in the effect of the floral scent. The results suggested that olfactory inputs through these organs play different roles in forming or modifying feeding preferences. Thus, our study contributes to an understanding of underlying mechanisms associated with the convergent processing of olfactory inputs with taste information, which affects feeding preference or appetite.
Nanoimprinted long-range surface plasmon polariton waveguide components (2006)

We report on the fabrication by nanoimprint lithography (NIL) and performance of metal stripe waveguides embedded in a polymer, capable of supporting long-range surface plasmon polariton (LRSPP) propagation.
ChemInform Abstract: The Influence of Interstitial Hydrogen, Carbon and Nitrogen Atoms on the Yttrium Hyperfine Field in Y2Fe17 and Y2Co17 (1991)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Effects of biodynamic coupling on the human operator model (1990)

Describing function models of the human operator in manual tracking tasks developed so far, have essentially been restricted to a static cockpit environment using fixed based simulators. This paper addresses the problem whether, and how, the response of the human operator and his associated describing function are influenced by cockpit motion induced by his own control commands. It is suggested, that the motion induced biodynamic stick feedthrough affecting the inner kinesthetic control loop, can be interpreted as a modification of the dynamics of the controlled vehicle. By assuming that the crossover model remains valid under conditions of vehicle motion, an extended analytical model of the human operator describing function is derived. Computer simulation of this analytical model provides reference characteristics of the describing function and remnant noise. A validation of this model, accomplished by extensive dynamical tests on a moving base simulator is described. The excellent match of the analytical and experimental characteristics obtained both in magnitude and shape substantiates the notion of the extended human operator model and suggests that it may contribute to improved overall pilot-aircraft system design.
Giant sigmoidal diverticulum (1978)

We present new results for three problems dealing with a set $\\mathcal{P}$ of $n$ convex constant-complexity fat polyhedra in 3-space. (i) We describe a data structure for vertical ray shooting in $\\mathcal{P}$ that has $O(\\log^2 n)$ query time and uses $O(n\\log^2 n)$ storage. (ii) We give an algorithm to compute in $O(n\\log^3 n)$ time a depth order on $\\mathcal{P}$ if it exists. (iii) We give an algorithm to verify in $O(n\\log^3 n)$ time whether a given order on $\\mathcal{P}$ is a valid depth order. All three results improve on previous results.
An Outbreak of Postoperative Gram‐Negative Bacterial Endophthalmitis Associated with Contaminated Trypan Blue Ophthalmic Solution (2009)

We report 6 cases of postsurgical endophthalmitis due to gram-negative bacteria associated with contaminated trypan blue dye from a compounding pharmacy. Unopened trypan blue syringes yielded Pseudomonas aeruginosa and Burkholderia cepacia complex on culture, with pulsed-field gel electrophoresis patterns indistinguishable from patient isolates. Contamination of compounded medications should be considered when investigating outbreaks of postoperative endophthalmitis.
Field repeatability in frequency diverse imaging (2016)

We consider multi-static imaging systems composed of frequency-diverse transmitting antenna arrays (or apertures). In these frequency diverse imaging modalities, accurate near-field characterization of the antennas is vital to achieving imaging. It is shown that considerable simplification in system characterization can be achieved without compromising the image quality when planar cavity antennas are used, because their radiation characteristics can be manufacture repeatable. In contrast, it is also demonstrated that the increased complexity of antennas utilizing sub-wavelength elements significantly reduces fabrication tolerances, making it necessary to characterize the metamaterial apertures individually.
Synthesis and Anti-Acetylcholinesterase Activity of Some 5-Substituted 1-Methyl-1 <i>H</i> -1,2,4-triazol-3-yl Methanesulfonates (1997)

5-Chloro-1-methyl-1,2-dihydro-3 H -1,2,4-triazol-3-one (12) and N -isopropyl-2-methyl-5-oxo-2,5-dihydro-1 H 1,2,4triazole3-sulfonamide (14) have been prepared from 1-methyl-5-thioxo-1,2,4-triazolidin-3-one (7) and converted into the methanesulfonate esters (15) and (16). The anti-acetylcholinesterase and insecticidal activities of (15) and (16) have been compared with those of the known 5-isobutylthio-1-methyl-1 H -1,2,4-triazol-3-yl methanesulfontate (4).
The spectrum of trebly-ionized bromine, Br IV (1934)

Vacuum spark and discharge-tube spectra of bromine have been investigated over a wide range. Many of the triplets and singlets involving the terms due to 4p, 5s, 4d, sp3 and 5p configurations have been identified. From the present work the classifications made by S. C. Deb appear to be incorrect. The deepest term 4p3P0, which equals 404892 cm.-1, yields an ionization potential of about 50 volts for the trebly-ionized atom of bromine.
A Similar Incidence of Transient Neurologic Symptoms After Spinal Anesthesia with 2% and 5% Lidocaine (1996)

Recent reports suggest that transient neurologic symptoms are common after spinal anesthesia with 5% lidocaine. To determine whether reducing the anesthetic concentration might decrease the incidence of symptoms, 50 ASA class I or II patients undergoing brief gynecologic procedures under spinal anesthesia were randomly allocated to receive 1 mg/kg of either 5% or 2% lidocaine in 7.5% glucose. Patients were evaluated on the first postoperative day by an anesthesiologist who was unaware of the solution administered or the details of the anesthetic procedure. Symptoms suggestive of transient radicular irritation were observed in 8 patients (32%) receiving 5% lidocaine, and in 10 patients (40%) receiving 2% lidocaine (NS). These results confirm our previous findings that transient neurologic symptoms may occur in up to one third of the patients receiving 5% lidocaine, and indicate that a modest reduction in lidocaine concentration does not reduce risk.
PERFORMANCE AND DESIGN STANDARDS FOR CONTROL WEIRS: AN INVESTIGATION OF DISCHARGE THROUGH SLOTTED WEIRS. FINAL REPORT (1993)

An experimental investigation of the hydraulic performance of notch weirs and orifices used for flow control is reported. Of concern is the effect that various aspects of the construction of these structures may have on discharge characteristics. In particular, the effect of finite crest breadth and very narrow widths has been examined. Various weir and orifice models typical of those found in practice have been tested in a recirculating flow facility. The results of these experiments have been presented in the form of empirical design equations along with recommendations for design standards. Analytical methods for assessing pond performance are discussed.
Modeling of test structures for efficient online defect monitoring using a digital tester (2002)

A novel methodology for digital measuring procedures and digital data analysis is presented in order to evaluate an online process control and defect monitoring. That can be done by manufacturing test chips side by side with standard chips and measuring them with the same measuring equipment-the digital tester. To achieve a fast and effective (efficient) measuring procedure and data analysis test structures will be modeled in geometry-graphs, neighborhood-graphs and connection-graphs.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Removal of trace chlorinated organic compounds by activated carbon and fixed-film bacteria (1982)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTRemoval of trace chlorinated organic compounds by activated carbon and fixed-film bacteriaEdward J. Bouwer and Perry L. McCartyCite this: Environ. Sci. Technol. 1982, 16, 12, 836–843Publication Date (Print):December 1, 1982Publication History Published online1 May 2002Published inissue 1 December 1982https://pubs.acs.org/doi/10.1021/es00106a003https://doi.org/10.1021/es00106a003research-articleACS PublicationsRequest reuse permissionsArticle Views498Altmetric-Citations81LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
On the influence of laser defocusing in Selective Laser Melting of 316L (2018)

Despite its many benefits, Selective Laser Melting's (SLM) relatively low productivity compared to deposition-based additive manufacturing techniques is a major drawback. Increasing the laser beam diameter improves SLM's build rate, but causes loss of precision. The aim of this study is to investigate laser beam focus shift, or “defocus”, using a dynamic focusing unit, in order to increase the laser spot size. When applied to the SLM process, focus shift can be integrated into a “hull-core” strategy. This involves scanning the core with a high productivity parameter set using defocus while enabling return to the focused smaller spot size position for hull scanning. To assess the process stability, single line scans were made from 316L stainless steel powder. The consolidated melt pool morphology was analyzed and correlated with the process parameters comprising laser power, scanning speed and defocus distance. In order to link the melt pool morphology with the heat input, Volumetric Energy Density, Normalized Enthalpy and Rosenthal equation were considered. The suitability of using the Normalized Enthalpy as a design parameter to predict the melt pool depth and Rosenthal equation to predict its width was highlighted. This study shows that within a single laser setup, implementing defocus can lead to a potential productivity increase by 840%, i.e. to 18.8 mm3/s.
Research on electrostatic monitoring technology for aero-engine gas path (2010)

Advanced monitoring tools must have the ability to monitor, diagnose and predict different aspects in order to achieve the overall health management of aero-engine. Electrostatic monitoring technology, as a method for improving the PUM capabilities of aero-engine, is presented in this paper. Firstly, the background, research and development status of electrostatic monitoring technology are introduced in brief Then, the key issues of electrostatic monitoring technology for aero-engine gas path, including basic principle, sensor technology, signal feature extraction and knowledge acquisition model, are proposed. Lastly, the challenges of electrostatic monitoring technology facing under the background of launching the large aircraft program plan in China are listed in the paper.