gebhart/patrepeval huggingface dataset:
Cyclodepsipeptides from Beauveria bassiana. Part 3. The isolation of beauverolides Ba, Ca, Ja, and Ka (1980)

Beauverolides Ja and Ka are shown to be the cyclotetradepsipeptides cyclo-[3-hydroxy-4-methyloctanoyl-L-tryptophyl-L-phenylalanyl-D-alloisoleucyl] and the 3-hydroxy-4-methyldecanoyl homologue, respectively. Pairs of beauverolides differing only in the hydroxy-acid residue are readily separated by high-pressure liquid chromatography and beauverolides Ba and Ca have been isolated using this technique.
Enhanced plasmon-loss emission along Al[011] chains upon heating (1991)

The Mg K\ensuremath{\alpha}--excited Al 2s core line and the subsequent inelastic plasmon-loss peaks have been measured as a function of temperature in an angle-resolved photoemission experiment. Along the [011] direction and along a lower-symmetry direction of an Al(001) crystal, the plasmon frequency decreases with increasing temperature, which is explained with the thermal expansion of Al. In contrast to the elastic Al 2s line, the plasmon peak intensities along [011] increase upon heating. This anomaly is interpreted as evidence for a temperature-induced destruction of the defocusing along high-density atomic chains.
SACS—Self-maintaining database of antibody crystal structure information (2002)

Summary of Antibody Crystal Structures (SACS), a self-maintaining web-site containing summary information on antibody structures in the PDB, is described. Mirrored PDB data are processed automatically using a Make-based system to identify new antibody structures. The PDB header records and sequence data are then parsed to identify a number of features of the structure and the data are stored using eXtensible Markup Language (XML). eXtensible Stylesheet Language: Transformations (XSLT), a new style sheet language for XML, is used to generate Hypertext Markup Language (HTML) pages containing either a one-line summary of every structure or a more detailed page describing a single antibody.
Assignment of the NAD-dependent deacetylase sirtuin 5 gene <i>(SIRT5)</i> to human chromosome band 6p23 by in situ hybridization (2006)

Sirtuin 5 (SIRT5) is a nicotinamide adenine dinucleotide (NAD+)-dependent deacetylase and belongs to the Silent information regulator 2 (Sir2) family of sirtuin histone deacetylases (HDACs), which play a central role in epigenetic gene silencing, DNA repair and recombination, cell-cycle, microtubule organization, and in the regulation of aging. We have isolated and characterized the human SIRT5 genomic sequence, which spans a region of 28,182 bp and which has one single genomic locus. Human SIRT5 consists of eight exons and is found in two isoforms, which encode a 310 aa and a 299 aa protein, respectively. Human SIRT5 is most predominantly expressed in heart muscle cells and in lymphoblasts. Fluorescence in situ hybridization analysis localized the human SIRT5 gene to chromosome 6p23.
Host range of Polymyxa betae Keskin strains in rhizomania-infested soils of sugar beet fields in Japan. (1986)

Host range of Polymyxa sp. isolated from various plants grown in rhizomania-infested soils of three different localities in Hokkaido was compared. Among 108 species of plants belonging to 23 families tested, 12 plants belonging to Chenopodiaceae, Amaranthaceae and Portulacaceae were infected with the fungus. The other 20 families including Gramineae were not infected. All isolates of Polymyxa sp. were identified as Polymyxa betae Keskin on the basis of their host range and morphological characteristics. The host range of the isolates was found to be limited to the family of the original host. Among the Chenopodiaceous isolates, that from sugar beet did not infect Chenopodium album, and those from C. album did not infect sugar beet. These P. betae isolates could be divided into several formae speciales; Amaranthus retroflexus isolates were identified as P. betae Keskin f. sp. amaranthi Barr, for the Portulaca oleracea isolates a new forma specialis P. betae Keskin f. sp. portulacae was proposed. Although sugar beet isolates and C. album isolates should be divided into different formae speciales, respectively, the classification of these isolates should await comparison with the Canadian isolate from C. album. From these results it is suggested that sugar beet isolates of P. betae which have a high infectivity to Beta vulgaris are associated with the incidence of rhizomania of sugar beet whereas the other two formae speciales and C. album isolates may not be involved.
Internet & World Wide Web How to Program (1999)

Internet & World Wide Web How to Program, 5/e is appropriate for both introductory and intermediate-level client-side and server-side programming courses. The book is also suitable for professionals who want to update their skills with the latest Internet and web programming technologies. Internet and World Wide Web How to Program, 5e introduces students with little or no programming experience to the exciting world of Web-Based applications. This new edition focuses on HTML5 and the related technologies in its ecosystem, diving into the exciting new features of HTML5, CSS3, the latest edition of JavaScript (ECMAScript 5) and HTML5 canvas. At the heart of the book is the Deitel signature live-code approachconcepts are presented in the context of complete working HTML5 documents, CSS3 stylesheets, JavaScript scripts, XML documents, programs and database files, rather than in code snippets. Each complete code example is accompanied by live sample executions.The Deitels focus on popular key technologies that will help readers build Internet- and web-based applications that interact with other applications and with databases. These form the basis of the kinds of enterprise-level, networked applications that are popular in industry today. After mastering the material in this book, readers will be well prepared to build real-world, industrial strength, Web-based applications.
Interaction of lithium with graphene: An<i>ab initio</i>study (2004)

The interaction potential of a $\mathrm{Li}$ atom with a graphene layer is calculated using the local density approximation to the density functional theory. Two configurations corresponding to different separations between $\mathrm{Li}$ in neighboring supercells were considered to determine the effect of $\mathrm{Li}\text{\ensuremath{-}}\mathrm{Li}$ interaction on the binding of $\mathrm{Li}$ to graphene. The equilibrium position of $\mathrm{Li}$ is not affected by the $\mathrm{Li}\text{\ensuremath{-}}\mathrm{Li}$ interaction and remains the same in both cases. It is equal to $3.1\phantom{\rule{0.3em}{0ex}}\mathrm{a.u.}$ above graphene with the $\mathrm{Li}$ at the center of a hexagonal ring formed by the carbon atoms. However, the binding energies differ substantially in the two configurations. The binding energy of $\mathrm{Li}$ is $0.934\phantom{\rule{0.3em}{0ex}}\mathrm{eV}$ in configuration A when the $\mathrm{Li}\text{\ensuremath{-}}\mathrm{Li}$ separation in adjacent supercells is $9.22\phantom{\rule{0.3em}{0ex}}\mathrm{a.u.}$ The binding energy is $1.598\phantom{\rule{0.3em}{0ex}}\mathrm{eV}$ in configuration B corresponding to a separation $18.45\phantom{\rule{0.3em}{0ex}}\mathrm{a.u.}$ between adjacent $\mathrm{Li}$ atoms. There is substantial charge transfer from both lithium and carbon atoms (including those that do not surround the lithium) to a region between the $\mathrm{Li}$ and graphene at the minimum energy configuration. The interaction potential for both configurations can be fitted to a sum of a screened Yukawa potential and a linear superposition of power-law functions of type ${r}^{\ensuremath{-}n}$, where $n$ is an integer. The density functional theory underestimates the attractive contribution of dispersion forces for large separations. The attractive interaction potential calculated for $\mathrm{Li}$ positions much greater than the equilibrium distance from graphene may therefore need to be corrected.
In-situ exploration of Mars using rover systems (2000)

This paper will describe a NASA/JPL rover system that has been focused on developing technologies required for the in-situ exploration of Mars. In particular, JPL has been developing a class of rovers that carrry significant payloads that address geological exploration and discovery along with the ability to acquire samples from soils and rocks.
Phenolphthalol (1952)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPhenolphthalolMax H. HubacherCite this: J. Am. Chem. Soc. 1952, 74, 20, 5216–5217Publication Date (Print):October 1, 1952Publication History Published online1 May 2002Published inissue 1 October 1952https://pubs.acs.org/doi/10.1021/ja01140a511https://doi.org/10.1021/ja01140a511research-articleACS PublicationsRequest reuse permissionsArticle Views75Altmetric-Citations3LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Optimal experimental design for in vitro studies with ELF magnetic fields (1990)

An experimental arrangement is described that maximized the dosimetric information that can be obtained during in vitro studies with ELF magnetic fields. The arrangement enables researchers to distinguish between a purely magnetic-field effect and one that also involves the electric fields and currents induced by the magnetic field.
Molecular diversity of sphingolipid signalling (1997)

Sphingolipid breakdown products are now being recognized to play a dual role in cellular signalling, acting as intracellular as well as extracellular signalling molecules. Both types of action may even be found with one sphingolipid species. The recent demonstration of G protein-coupled receptors with high affinity for sphingosine 1-phosphate and sphingosylphosphorylcholine has been followed by the discovery of several novel sphingolipid actions, such as regulation of heart rate, oxidative burst, neurite retraction or platelet activation. Ligand profiles and concentration-response relationships suggest the existence of putative sphingolipid receptor subtypes. Against this background, several observations on supposed sphingolipid second messenger actions deserve a new evaluation.
Thermal acceptor formation in nitrogen-doped silicon (1991)

The nitrogen-doped Czochralski (CZ) silicon crystals were grown in a nitrogen atmosphere under reduced pressure. The results show that the resistivity of n-type N-doped silicon increases rapidly with annealing time above 700 °C, but that of p-type N-doped CZ silicon decreases rapidly under the same conditions. It is suggested that thermal acceptors (TA) are formed in N-doped silicon. The concentration of thermal acceptor can reach to 1×1014 atom/cm3. The higher the annealing temperature, the longer the time for the maximum thermal acceptor concentration to appear. Nitrogen and oxygen impurities play important roles for generating the thermal acceptor. It is postulated that the thermal acceptor is a kind of Si-O-N complex.
MODELING HUMAN INTERACTION TO DESIGN A HUMAN-COMPUTER DIALOG SYSTEM (2008)

This article presents the Cogni-CISMeF project, which aims at improving the health information search engine CISMeF, by including a conversational agent that interacts with the user in natural language. To study the cognitive processes involved during information search, a bottom-up methodology was adopted. An experiment has been set up to obtain human dialogs related to such searches. The analysis of these dialogs underlines the establishment of a common ground and accommodation effects to the user. A model of artificial agent is proposed, that guides the user by proposing examples, assistance and choices.
BayesPeak—an R package for analysing ChIP-seq data (2011)

Available as part of BioConductor version 2.6. URL: http://bioconductor.org/packages/release/bioc/html/BayesPeak.html.
Catheter-Related Interventions to Prevent Peritonitis in Peritoneal Dialysis (2004)

As many as 15 to 50% of end-stage kidney disease patients are on peritoneal dialysis (PD), but peritonitis limits its more widespread use. Several PD catheter-related interventions (catheter designs, surgical insertion approaches, and connection methods) have been purported to reduce the risk of peritonitis in PD. The goal was to assess the trial evidence supporting their use. The Cochrane CENTRAL Registry, MEDLINE, EMBASE, and reference lists were searched for randomized trials of catheter types and related interventions in PD. Two reviewers extracted data on the rates of peritonitis and exit-site/tunnel infection, catheter removal/replacement, technique failure, and all-cause mortality. Analysis was by a random effects model, and results are expressed as relative risk and 95% confidence intervals. Thirty-seven eligible trials (2822 patients) were identified: eight of surgical strategies of catheter insertion, eight of straight versus coiled catheters, 10 of Y-set versus conventional spike systems, four of Y-set versus double-bag systems, and seven of other interventions. Despite the large total number of patients, few trials covered the same interventions, small numbers of patients were enrolled in each trial, and the methodologic quality was suboptimal. Y-set and twin-bag systems were superior to conventional spike systems (seven trials, 485 patients; relative risk, 0.64; 95% confidence intervals 0.53 to 0.77), and no other catheter-related intervention was demonstrated to prevent peritonitis in PD. This systematic review demonstrates that of all catheter-related interventions designed to prevent peritonitis in PD, only disconnect (twin-bag and Y-set) systems have been proved to be effective (compared with conventional spike systems). Despite the importance of PD as a renal replacement therapy modality and the large number of patients who receive it, it is still not known whether any particular PD catheter designs, implantation techniques, or modalities are effective, given the limitations of available trials.
Theory of parametric frequency down conversion of light (1985)

A theoretical study is made of the process in which incident pump photons that interact with a nonlinear medium (such as a crystal lacking inversion symmetry) are spontaneously split into lower-frequency signal and idler photons. The down-converted fields are quantized and described by a continuum of modes, a subset of which interacts with each photodetector. It is shown that when two ideal photodetectors are appropriately located so that they receive the conjugate signal and idler photons, then the joint probability of two-photon detection by the two detectors can equal the single-photon detection probability. The time correlation between the two detected photons is shown to be limited either by the resolving time of the detectors, or by the bandwidth of the down-converted light, and to be independent of the coherence time of the pump field or of the length of the nonlinear medium. These conclusions are compared with the results of recent experiments.
GLOSSÁRIO DE EPIDEMIOLOGIA (1956)

The author discusses the need of having a glossary of epidemiologic terms, in order to reach uniformity in nomenclaturc. He points out the advantages that would result, bearing in mind that the establishment of such terms and their meaning at National Congresses would be convenient, and it would then be possible to adopt them ali over Brazil. He suggests also that glossaries for other branches of Public Health should be prepared. We would have, then, a dictionary, of great use to our Public Health workers. Finally, the author presents a list of the chief terms used in Epidemiology, nearly two hundred, classified in alphabetical order, with their respective meanings, synonyms, and examples.
Role of Insulin-Induced Reactive Oxygen Species in the Insulin Signaling Pathway (2005)

Oxidants, including hydrogen peroxide (H2O2), have been recognized for years to mimic insulin action on glucose transport in adipose cells. Early studies also demonstrated the complementary finding that H2O2 was elaborated during treatment of cells with insulin, suggesting that cellular H2O2 generation was integral to insulin signaling. Recently, reactive oxygen species elicited by various hormones and growth factors have been shown to affect signal transduction pathways in various cell types. We recently reported that insulin-stimulated H2O2 modulates proximal and distal insulin signaling, at least in part through the oxidative inhibition of protein tyrosine phosphatases (PTPases) that negatively regulate the insulin action pathway. Nox4, a homologue in the family of NADPH oxidase catalytic subunits, was found to be prominently expressed in insulin-sensitive cells. By various molecular approaches, Nox4 was shown to mediate insulin-stimulated H2O2 generation and impact the insulin signaling cascade. Overexpression of Nox4 also significantly reversed the inhibition of insulin-stimulated receptor tyrosine phosphorylation by PTP1B, a widely expressed PTPase implicated in the negative regulation of insulin signaling, by inhibiting its catalytic activity. These recent studies have provided insight into Nox4 as a novel molecular link between insulin-stimulated reactive oxygen species and mechanisms involved in their modulation of insulin signal transduction.
(INVITED) Recent advances in ultraviolet persistent phosphors (2019)

Phosphors with the ultraviolet (UV) persistent luminescence (PersL) may have potential applications such as photo-catalysis, anti-counterfeiting, water disinfecting and photochemistry. Up to now, no more than 20 UV PersL phosphors have been discovered, and no reviews of these UV PersL phosphors and the development in this field have been reported. For this regard, we present an overview of the known UV PersL materials and their PersL properties and list all possible challenges. We wish that this review could offer new inspirations for the following development of persistent luminescence in UV ranges and related applications.
[Cerebral thrombophlebitis, sural phlebitis, pulmonary embolisms and protein S deficiencies]. (1996)

The authors report about a patient with thrombosis of the transverse and sigmoid sinus who also suffered from multiple pulmonary embolism and deep leg vein thrombosis. The etiologic factor was a deficiency of the free (unbounded) and total protein S. The cerebral sinus thrombosis was diagnosed by MRI and angio-MRI. The first 4 weeks the patient was treated with heparin and later with phen-procoumon. The plasma protein S serves as a cofactor for protein C and plays an important role in the anticoagulation. Deficiencies of these proteins are either hereditary with an autosomal dominant trait or acquired in patients with severe hepatic diseases and coagulation disorders.
Wavelength-Dependent Photolysis of Glyoxal in the 290−420 nm Region (2003)

We have studied the gas-phase photolysis of glyoxal, (CHO)2, at 10 nm intervals in the 290−420 nm region by using dye laser photolysis coupled with cavity ring-down spectroscopy. Absorption cross sections of glyoxal have been measured. The HCO radical is its photodissociation product. The dependence of the HCO quantum yield on photodissociation wavelength, glyoxal pressure, and nitrogen buffer gas pressure has been determined. The HCO yields decrease with increasing glyoxal pressure in the 1−8 Torr range, owing to the increasing HCO radical reactions at higher glyoxal pressures and quenching by ground-state glyoxal. After separation of the contribution of HCO radical reactions, the aldehyde pressure quenching effect was still observed in the 320−420 nm region, and this effect increased with increasing wavelength. The HCO radical yields (all λ) and the ratios of quenching to unimolecular decay rate constants of excited glyoxal (λ ≥ 320 nm) are given. The peak HCO yield is 2.01 ± 0.08 (error quoted only includes 1σ measurement uncertainty) at 390 nm, consistent with the occurrence of the (HCO)2 + hν → 2HCO channel. The HCO radical yields are around 1.56 ± 0.22 in the 320−370 nm region, indicating the simultaneous occurrence of (HCO)2 + hν → 2HCO and (HCO)2 + hν → HCO + H + CO channels. The HCO radical yields are 0.50 ± 0.01, 0.68 ± 0.02, and 0.84 ± 0.07 at 290, 300, and 310 nm, respectively, which may suggest the opening of an additional photolysis channel at higher photon energies. The dependence of the HCO quantum yield on nitrogen buffer gas pressure was examined between 10 and 400 Torr. The HCO radical yields are independent of nitrogen pressure in the 290−370 nm range, but they decrease with increasing nitrogen pressure in the 380−420 nm region. A comparison of the wavelength-dependent HCO radical yields with results obtained from previous dynamics and quenching studies provides insight into the mechanism of glyoxal photodissociation as a function of wavelength.
Miniaturisierte Instrumente aus Nickel-Titan-Legierungen für die minimal invasive Therapie (2000)

gische Eingriffe in den Bereichen der endoskopischen Neurochirurgie, der Urologie, der interventionellen Kardiologie und der Gynakologie werden in absehbarer Zeit extrem miniaturisierte Operationsinstrumentarien benotigt, welche mit den derzeit verfugbaren feinwerktechnischen Methoden nicht mehr gefertigt werden konnen. Immer haufiger muss heutzutage ein chirurgischer Eingriff in schwer erreichbaren Bereichen bzw. in sehr engen oder „raumlosen“ Lumina des menschlichen Korpers vorgenommen werden. Wunschenswert sind daher Instrumente mit geringen Ausenabmessungen, die dennoch sicher zum Operationssitus vorgefuhrt und vor Ort sicher bedient werden konnen. Kleinste Greifund Schneidinstrumente konnen auf der Basis von superelastischen Nickel-Titan-Legierungen (NiTi) realisiert werden [1]. Am IMT wurde ein Fertigungsverfahren entwickelt und optimiert mit dem die Herstellung von NiTi-Mikroinstrumenten moglich ist. Dazu werden mit der μEDM-Technik (Mikroerodiertechnik) die benotigten Mikrostrukturen der Instrumente in dunne NiTi-Drahte, -Rohrchen und -Plattchen hineingearbeitet. Die ursprunglich im Rahmen des BMBF-Verbundprojektes MINOP (Mikrosystemtechnik zum Einsatz in der minimal invasiven neurochirurgischen Operationstechnik; Forderkennzeichen 13 MV 0323) entwickelten Mikroinstrumente [2, 3] wurden zwischenzeitlich gemeinsam mit medizinischen Partnern fur neue Einsatzgebiete weiterentwickelt, da in den oben genannten Fachdisziplinen verschiedene Formen von starren oder flexiblen miniaturisierten Instrumenten zum Greifen, Schneiden, Saugen/Spulen sowie zum Fuhren von Hilfsund Zusatzinstrumenten benotigt werden. Der vorliegende Bericht gibt den Stand der beendeten FuE-Arbeiten wieder und stellt ruckblickend die Fertigung und mogliche medizinische Einsatzgebiete fur miniaturisierte Instrumente vor.