gebhart/patrepeval huggingface dataset:
Designing broadcasting algorithms in the postal model for message-passing systems (1992)

Article Free Access Share on Designing broadcasting algorithms in the postal model for message-passing systems Authors: Amotz Bar-Noy View Profile , Shlomo Kipnis View Profile Authors Info & Claims SPAA '92: Proceedings of the fourth annual ACM symposium on Parallel algorithms and architecturesJune 1992 Pages 13–22https://doi.org/10.1145/140901.140903Published:01 June 1992Publication History 76citation498DownloadsMetricsTotal Citations76Total Downloads498Last 12 Months26Last 6 weeks2 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteeReaderPDF
NetMod: A Design Tool for Large-Scale Heterogeneous Campus Networks (1990)

The Network Modeling Tool (NetMod) uses simple analytical models to provide the designers of large interconnected local area networks with an in-depth analysis of the potential performance of these systems. This tool can be used in either a university, industrial, or governmental campus networking environment consisting of thousands of computer sites. NetMod is implemented with a combination of the easy-to-use Macintosh software packages HyperCard and Excel. The objectives of NetMod, the analytical models, and the user interface are described in detail along with its application to an actual campus-wide network. 1 1. Introduction The Network Modeling Tool (NetMod) assists the development of an in-depth understanding of the performance of state-of-the-art local area network (LAN) technologies in either a university, industrial, or government campus networking environment consisting of thousands of computer sites. A principal application of the tool is to help the campus network design...
Synergistic Activation of NFAT by HIV-1 Nef and the Ras/MAPK Pathway (2000)

Nef is a lentiviral protein involved in pathogenesis of AIDS, but its molecular mechanisms of action remain incompletely understood. Here we report a novel effect of Nef on lymphocyte signaling, which is mediated via a T cell receptor (TCR)-independent contribution of Nef to induction of nuclear factor of activated T cells (NFAT), a transcription factor that plays a central role in coordinating T cell activation. Expression of Nef did not significantly alter the basal level of NFAT activity in Jurkat cells nor the increased activity following T cell receptor stimulation by anti-CD3 or anti-CD3 + anti-CD28. We also mimicked NFAT induction by TCR triggering by simultaneous activation of the Ras and calcium signaling pathways with phorbol 12-myristate 13-acetate and ionomycin, respectively. Strikingly, whereas activation of either of these pathways individually did not induce NFAT activity in control cells, in Nef-expressing cells phorbol 12-myristate 13-acetate treatment alone resulted in a 100-fold increase in NFAT-directed gene expression. Experiments with different dominant negative mutant signaling proteins, inhibitory chemicals, and Lck-deficient Jurkat cells revealed that this effect was mediated via activation of calcineurin by Nef-induced changes in calcium metabolism, but was independent of TCR-associated signaling events. This ability of Nef to substitute for triggering of the calcium pathway in induction of NFAT could promote activation of human immunodeficiency virus (HIV)-infected T cells in response to stimuli mediated via TCR or other cell surface receptors under conditions when activation of Ras rather than calcium signaling would otherwise predominate.
DNA modifications in the mammalian brain (2014)

DNA methylation is a crucial epigenetic mark in mammalian development, genomic imprinting, X-inactivation, chromosomal stability and suppressing parasitic DNA elements. DNA methylation in neurons has also been suggested to play important roles for mammalian neuronal functions, and learning and memory. In this review, we first summarize recent discoveries and fundamental principles of DNA modifications in the general epigenetics field. We then describe the profiles of different DNA modifications in the mammalian brain genome. Finally, we discuss roles of DNA modifications in mammalian brain development and function.
Études post-génomiques de la spermatogénèse chez les mammifères (2008)

L’infertilite constitue une preoccupation de sante grandissante : En Europe environ quinze pour cent des couples connaissent des problemes de fertilite et, dans pres d’un cas sur deux, l’hypofertilite est d’origine masculine et son etiologie demeure inconnue. Mes travaux de these ont consiste a etudier la spermatogenese des mammiferes, essentiellement chez les rongeurs mais aussi chez l’homme, par des approches relevant de la post-genomique. Au cours d’une premiere etude plusieurs milliers de genes presentant des variations d’expression au cours de la differenciation des cellules germinales mâles chez la souris, le rat, et l’homme, ont ete identifies. Parmi ces genes, 888 sont conserves chez les trois especes et presentent des profils d’expression egalement conserves au cours de l’evolution, suggerant des fonctions importantes au cours de la gametogenese mâle. Dans une seconde etude, 123 proteines presentant de fortes variation d’expression au cours de la differenciation de ces cellules germinales ont pu etre identifiees chez le rat, et sont autant de marqueurs potentiels de la spermatogenese normale chez l’homme. La comparaison de ces donnees chez le rat permet par ailleurs d’apprehender l’etude des regulations post-transcriptionnelles necessaires a la formation des gametes mâles. La meconnaissance actuelle de la physiopathologie testiculaire s’explique notamment par la limite meme des connaissances du fonctionnement normal du testicule humain. Les resultats obtenus au cours de ma these sont de nature a donner une impulsion decisive dans nos connaissances des genes regulant la differenciation des cellules germinales mâles.
<b>The Synthesis of a Heptadecapeptide Possessing Adrenocorticotropic, Melanotropic and Lipolytic Activities</b> (1962)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe Synthesis of a Heptadecapeptide Possessing Adrenocorticotropic, Melanotropic and Lipolytic ActivitiesChoh Hao. Li, David. Chung, Janakiraman. Ramachandran, and Boris. GorupCite this: J. Am. Chem. Soc. 1962, 84, 12, 2460–2462Publication Date (Print):June 1, 1962Publication History Published online1 May 2002Published inissue 1 June 1962https://pubs.acs.org/doi/10.1021/ja00871a046https://doi.org/10.1021/ja00871a046research-articleACS PublicationsRequest reuse permissionsArticle Views42Altmetric-Citations25LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Notizen: Electric Field Dependence of the Ionization Threshold of Benzene and the Benzene-Argon Complex (1981)

The ionization potential measured as a threshold to photoionization for benzene and the benzene-argon com­plex is shown to be a strong function of the applied electric field required to detect the ionization event. The ionization potential is lowered by moderate electric fields and the field dependence is found to be the same for the bare molecule and its Van der Waals complex. The data can be fitted with a square root dependence on the electric field and this shows that large molecules behave like atoms at the ionization threshold.
Nonlinear optical endoscopy (2010)

Ever since researchers realised that microscopy based on nonlinear optical effects can provide information that is blind to conventional linear techniques, applying nonlinear optical imaging to in vivo medical diagnosis in humans has been the ultimate goal. The development of nonlinear optical endoscopy that permits imaging under conditions in which a conventional nonlinear optical microscope cannot be used is the primary method to extend applications of nonlinear optical microscopy toward this goal. Fibreoptic approaches that allow for remote delivery and collection in a minimally invasive manner are normally used in nonlinear optical endoscopy. In Chapter 4, a compact nonlinear optical microscope based on a single-mode fibre (SMF) coupler to replace complicated bulk optics was described.
Japan Implantable Devices in Coronary Artery Disease (JID‐CAD) study design (2014)

In this report, we discuss the current clinical situation of appropriate therapy, and how it is influenced by catheter ablation and revascularization therapy in patients with CAD.
Isolation of an Unidentified Agent from the Respiratory Tract of Chickens (1960)

A relatively stable filterable virus, not previously described, which hemagglutinated red blood cells of chickens, was isolated from the tracheae of birds suffering from an unusually severe outbreak of infectious laryngotracheitis. The latter disease concealed the infection caused by the new hemagglutinating agent, which was shown to cause, by itself, a mild and transient illness in susceptible chickens. Preliminary studies indicate that the new agent may be a new entity of the myxovirus group.
Synthesis of nitrosothioureas. 15N N.m.r. evidence for the formation of thionitrosyl compounds in the nitrosation of thioureas (1981)

Nitrosothioureas may be prepared by treatment of thioureas with NaNO2 in 0·1 N HCl at –5 °C by direct N-nitrosation whereas 15N n.m.r. studies at –10 °C which employed specifically 15N-enriched compounds revealed the intermediacy of a thionitrosyl compound under more acidic conditions which gave the urea by hydrolysis.
Comparison of marker types and map assumptions using Markov chain Monte Carlo-based linkage analysis of COGA data (2005)

We performed multipoint linkage analysis of the electrophysiological trait ECB21 on chromosome 4 in the full pedigrees provided by the Collaborative Study on the Genetics of Alcoholism (COGA). Three Markov chain Monte Carlo (MCMC)-based approaches were applied to the provided and re-estimated genetic maps and to five different marker panels consisting of microsatellite (STRP) and/or SNP markers at various densities. We found evidence of linkage near the GABRB1 STRP using all methods, maps, and marker panels. Difficulties encountered with SNP panels included convergence problems and demanding computations.
Biosynthesis of Oleoside-, 10-Hydroxyoleoside- and Ligustaloside-Type Glucosides from Secologanin. (1999)

A biosynthetic pathway from secologanin to oleoside-, 10-hydroxyoleoside- and ligustaloside-type secoiridoid glucosides was examined by feeding experiments in which the respective C-8 stereoisomers of [8-3H]-8, 10-epoxyse cologanin and [8-3H]-8, 10-epoxysecoxyloganin as well as [carbomethoxy-2H3]secologanin were administered separately to three oleaceous plants. The results showed that (8S)-8, 10-epoxysecologanin was an intermediate between the secologanin and secoiridoid glucosides of the three types.
Micrometer scale magnetization of neodymium magnet for integrated magnetic MEMS (2016)

In order to fabricate integrated magnetic MEMS devices containing complex micro-magnetic circuits, a micrometer scale magnetization technique for magnet substrates is required. Miniaturization of the magnetization pattern generated by pulse magnetization is limited due to heat resistance and the arrangement of the micro-coils. In this paper, we discuss a micro-magnetization method utilizing weakening of the magnetic coercivity by laser assisted heating. The heat conduction paths in the magnet substrate and the conditions used for the laser assisted heating for realizing particular designed magnetization patterns were examined. Finally, stripe and chessboard magnetization patterns on neodymium magnet substrates were experimentally tested and evaluated.
Role of <i>Escherichia Coli</i> Histone‐Like Nucleoid‐Structuring Protein in Bacterial Metabolism and Stress Response (1997)

The histone-like nucleoid-structuring protein, H-NS, is a major bacterial chromatin component which influences DNA structure and gene expression. Mutations in hns, the structural gene of H-NS protein, have been shown to result in highly pleiotropic effects in Escherichia coli cells. In this study, we have initiated an index of the proteins whose synthesis is, directly or indirectly regulated by H-NS. Using two-dimensional gel electrophoresis, we have examined the global changes in gene expression which occured in an hns background compared with its wild-type parent. In addition, we analysed the effects of mutations in two other genes i.e. lrp and pta, which are also involved in global regulatory pathways. Although these comparative analyses revealed several common differences, thus suggesting possible interactions between these regulatory mechanisms, i.e. H-NS, Lrp (leucine-responsive regulatory protein) and acetylphosphate, the most extensive modifications occurred in an hns mutant. Among the polypeptides whose level of synthesis was specifically altered in an hns mutant, several corresponded to H-NS targets previously identified by classical selection methods. Moreover, the present study allows us to characterize several H-NS targets, which were identified either by comparison with the E. coli two-dimensional reference maps or by microsequencing procedure. Many of these newly identified polypeptides are involved in adaptation of E. coli cells to environmental challenges, and one of them could be involved in bacterial virulence. Finally, synthesis of several proteins belonging to the heat-shock regulon, more particularly molecular chaperones, was induced in an hns mutant.
A Functional Technique for Decomposing the Complexity of Requirements Analysis (1981)

Abstract : This paper is based on an 'operational' approach to requirements specification for embedded systems, in which a requirements specification is an executable model of the proposed system interacting with its environment. The operational model is described in terms of asynchronously interacting digital processes. This paper addresses directly the question: How can such specifications for complex systems be developed? The proposed technique exploits an identification of intuitively recognizable system functions with processes in the formal specification of that system, so that its process structure can be determined during early analysis. Since the formal language supports incremental development of a specification, one process at a time, the requirements analyst can then elaborate the requirements one function at a time. Since the elaboration of each function entails quite a number of decisions, significant decomposition of complexity is achieved. The technique is illustrated within the domain of process-control systems, but its extensibility to other applications is argued. The specifications produced are good with respect to several important criteria, including modifiability and representation of performance constraints.
Synthèses et caractérisations structurales de complexes perchlorato et triflato anhydres de praseodyme(III) (1994)

The syntheses of Pr(ClO 4 ) 3 , Pr(OTf) 3 (OTf = CF 3 SO 3 ), Pr(ClO 4 ) 3 •Cl 2 O 6 , and NO 2 Pr(ClO 4 ) 4 are described. Vibrational spectroscopy, X-ray powder diffraction, and EXAFS (for Pr(ClO 4 ) 3 ) are used to characterize the structure of the complexes. [ClO 4 ] and [OTf] appear as tridentate in Pr(ClO 4 ) 3 and Pr(OTf) 3 and Pr is 9-coordinated. In Pr(ClO 4 ) 3 •Cl 2 O 6 , chlorine trioxide is included in the lattice of Pr(ClO 4 ) 3 and shows the ionic ↔ covalent equilibrium. In NO 2 Pr(ClO 4 ) 4 , Pr(ClO 4 ) 4 − retains the structure of Pr(ClO 4 ) 3 , the extra [ClO 4 ] is weakly bonded to Pr • Pr(ClO 4 ) 3 crystallizes in the monoclinic system (P2 1 /m), a = 8.608; b = 11.827; c = 7.416 Å; β = 106.29°, and V = 724.79 Å 3 . Distances Pr—O = 2.51 Å and Pr—Cl = 3.90 Å are determined by EXAFS. Strong fluorescence phenomena are observed when Pr(ClO 4 ) 3 is excited with the 488 nm line of an ionized Ar laser.
Abiotic Reductive Dechlorination of Chlorinated Ethylenes by Iron-Bearing Soil Minerals. 2. Green Rust (2002)

Abiotic reductive dechlorination of chlorinated ethylenes by the sulfate form of green rust (GR(SO4)) was examined in batch reactors. Dechlorination kinetics were described by a modified Langmuir-Hinshelwood model. The rate constant for reductive dechlorination of chlorinated ethylenes at reactive GR(SO4) surfaces was in the range of 0.592 (+/-4.4%) to 1.59 (+/-6.3%) day(-1). The specific reductive capacity of GR(SO4) for target organics was in the range of 9.86 (+/-10.1%) to 18.0 (+/-4.3%) microM/g and sorption coefficient was in the range of 0.53 (+/-2.4%) to 1.22 (+/-4.3%) mM(-1). Surface area-normalized pseudo-first-order initial rate constants for chlorinated ethylenes by GR(SO4) were 3.4 to 8.2 times greater than those by pyrite. Chlorinated ethylenes were mainly transformed to acetylene, and no detectable amounts of chlorinated intermediates were observed. The rate constants for the reductive dechlorination of trichloroethylene (TCE) increased as pH increased (6.8 to 10.1) but were independent of solid concentration and initial TCE concentration. Magnetite and/or maghemite were produced by the oxidation of GR(SO4) by TCE. These findings are relevant to the understanding of the role of abiotic reductive dechlorination during natural attenuation in environments that contain GR(SO4).
ChemInform Abstract: Crystal Engineering and Solid State Chemistry of Some β‐ Nitrostyrenes (1992)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Evolutionary relationships in the cucumoviruses: nucleotide sequence of tomato aspermy virus RNA 1 (1991)

RNA 1 of the V strain of tomato aspermy virus (TAV) consists of 3410 nucleotides and contains one open reading frame (ORF) of 2982 nucleotides, resembling RNA 1 of cucumber mosaic virus (CMV) strains Q and Fny (68% and 66% identical, respectively) and of brome mosaic virus (BMV) (41% identical). In comparisons between amino acid sequences, three conserved regions (N-terminal, C-terminal and central) between TAV and each CMV were found. The N- and C-terminal regions were also conserved with BMV, and contained, respectively, consensus motifs for methyltransferases and for nucleic acid helicases. The 5' and 3' non-coding sequences were highly similar to those of TAV RNA 2. When the sequences for the genomic RNAs of the V and C strains of TAV, and of their encoded products, are compared with those reported for CMV strains representing either subgroup I (Fny-CMV) or subgroup II (Q-CMV) of CMV, it was found that the different virus-encoded proteins are conserved differently between these three viruses. Also, the divergence between TAV and both CMV subgroups has proceeded at different rates for the different ORFs. On the whole, the divergence between TAV and CMV is of the same order as that found between CMV subgroups I and II, which suggests that TAV, Q-CMV and Fny-CMV could be considered as representing three equivalent subgroups of a taxonomic entity.
A Walsh-Hadamard Transform LSI for Speech Recognition (1982)

Abstract- Speech recognition systems are coming to a practical stage thanks to the recent progress of the semiconductor technology. We have developed a low cost speaker-dependent speech recognition unit using Walsh-Hadamard transform (WIT). A WHT LSI has been developed to reduce the cost and the space of the recognition unit, and a high rate of recognition has been obtained. The speech recognition algorithm and the LSI are described in this paper.
Onset of a Propagating Self-Sustained Spin Reversal Front in a Magnetic System (2013)

The energy released in a magnetic material by reversing spins as they relax toward equilibrium can lead to a dynamical instability that ignites self-sustained rapid relaxation along a deflagration front that propagates at a constant subsonic speed. Using a trigger heat pulse and transverse and longitudinal magnetic fields, we investigate and control the crossover between thermally driven magnetic relaxation and magnetic deflagration in single crystals of Mn(12)-acetate.
Frequency of Concurrent Autoimmune Disorders in Patients With Autoimmune Hepatitis (2008)

The nature, but not the frequency, of CAID was shown to vary in AIH-1 and AIH-2. In subjects with AIH-1, CAID was linked to older subjects and to the presence of antinuclear antibody. No predisposition to CAID was associated to HLA-DRB1*04 or DDB4*01 alleles. The observed lower frequency of CAID could be attributed to the lower age of disease onset in Brazilians and to differences in HLA-encoded susceptibility to AIH-1 observed in South America.
Electronic structure, properties, and phase stability of inorganic crystals: A pseudopotential plane-wave study (2000)

Recent developments in density functional theory (DFT) methods applicable to studies of large periodic systems are outlined. During the past three decades, DFT has become an essential part of computational materials science, addressing problems in materials design and processing. The theory allows us to interpret experimental data and to generate property data (such as binding energies of molecules on surfaces) for known materials, and also serves as an aid in the search for and design of novel materials and processes. A number of algorithmic implementations are currently being used, including ultrasoft pseudopotentials, efficient iterative schemes for solving the one-electron DFT equations, and computationally efficient codes for massively parallel computers. The first part of this article provides an overview of plane-wave pseudopotential DFT methods. Their capabilities are subsequently illustrated by examples including the prediction of crystal structures, the study of the compressibility of minerals, and applications to pressure-induced phase transitions. Future theoretical and computational developments are expected to lead to improved accuracy and to treatment of larger systems with a higher computational efficiency. © 2000 John Wiley & Sons, Inc. Int J Quant Chem 77: 895–910, 2000