gebhart/patrepeval huggingface dataset:
Intrathoracic extramedullary hematopoiesis simulating posterior mediastinal mass--report of a case in patient with beta-thalassemia intermedia. (1991)

Intrathoracic involvement of the extramedullary hematopoiesis is a rare condition. It is usually found in patients with thalassemia or hereditary spherocytosis. In the literature, only 79 cases have been reported. Here, in Taiwan, a 22 year-old female patient of beta-thalassemia intermedia presented with posterior mediastinal mass proved as an intrathoracic extramedullary hematopoiesis by thoracoscopic biopsy was reported.
Regulation of APG14 Expression by the GATA-type Transcription Factor Gln3p (2001)

Gln3p is a nitrogen catabolite repression-sensitive GATA-type transcription factor. Its nuclear accumulation was recently shown to be under the control of TOR signaling. Gln3p normally resides in the cytoplasm. When cells are starved from nitrogen nutrients or treated with rapamycin, however, Gln3p becomes translocated into the nucleus, thereby activating the expression of genes involved in nitrogen utilization and transport. To identify other genes under the control of Gln3p, we searched for the Gln3p-binding GATAA motifs within 500 base pairs of the promoter sequences upstream of the yeast open reading frames in the Saccharomyces Genome Database. APG14, a gene essential for autophagy, was found to have the most GATAA motifs. We show that nitrogen starvation or rapamycin treatment rapidly causes a more than 20-fold induction of APG14. The expression of APG14 is dependent on Gln3p; deletion of Gln3p severely reduced its induction by rapamycin, whereas depletion of Ure2p caused its constitutive expression. However, overexpression of APG14 led to only a slight increase in autophagy in nitrogen-rich medium. Therefore, these results define a signaling cascade leading to the expression of APG14 in response to the availability of nitrogen nutrients and suggest that the regulated expression of APG14 contributes to but is not sufficient for the control of autophagy.
MIPS RISC architecture (1988)

1. RISC Architecture: An Overview. 2. MIPS Processor Architecture Overview. 3. CPU Instruction Set Summary. 4. Memory Management System. 5. Caches. 6. Exception Processing. 7. FPU Overview. 8. FPU Instruction Set Summary and Instruction Pipeline. 9. Floating Point Exceptions. Appendixes. Index.
Towards model-based design support for distributed user interfaces (2004)

User Interface design has been evolving for years to keep pace with different emerging technologies that effect human-computer interaction. Formal techniques for command-line interfaces, Drag-and-drop User Interface creation for Graphical User Interfaces and Model-Based Interface Design for Multi-Device User Interfaces are a few examples of this evolution. Nowadays communication channels between devices are getting faster, more reliable and will be omnipresent in a matter of time. Human interaction will no longer be about interaction with one device, but involves interacting with a network of devices cooperating as a set of <i>interaction resources.</i> Based on well-known concepts from distributed systems and model-based User Interface Design we develop a model for <i>distributed user interfaces.</i> One missing piece is support for distributed interfaces in the models used during the design of user interfaces. We will discuss how Dygimes, a testbed for model-based user interface development, provides support for distributed user interfaces. User mobility is a key issue, since mostly ubiquitous environments will benefit of distributed User Interfaces. In every respect location transparency plays an important role for human-device and device-device interaction.
Polygyny in the Northern Saw-whet Owl (1989)

Description de deux cas de polygynie chez Aegolius acadicus. La polygynie est basee sur le fait que le mâle nourrit plusieurs femelles ou les jeunes de celles-ci
Introduction Changing patterns of health professional governance (2008)

Abstract Across many countries, professional governance is under the spotlight of health policy makers and subject to public debate. This book provides new data and geopolitical perspectives in the debate over how to govern healthcare. It sets out to highlight new international directions and the significance of national contexts for the changing health workforce based on complex sets of cultural and institutional regulatory patterns. One central goal of the new health policies that are emerging is accountability and control of professionals, which in turn calls for tighter regulation and new forms of professional development. This chapter describes the changing context of professional governance, researching the changing international governance in healthcare, new health policies remaking state-professions-citizens relationships, professional development and the structure of the book.
MG53 is a double-edged sword for human diseases. (2016)

Mitsugumin 53 (MG53), also named Trim72, is a multi-functional TRIM-family protein, which is abundantly expressed in cardiac and skeletal muscle. It has been shown that MG53 not only plays important physiological roles but also acts as a crucial pathogenic factor of various diseases. First, MG53 preserves cardiac and skeletal muscle integrity via facilitating plasma membrane repair. Second, MG53 is essentially involved in cardiac ischemic preconditioning and postconditioning by activating PI3K-Akt-GSK3β and ERK1/2 cell survival signaling pathways. Moreover, systemic delivery of recombinant MG53 is able to abolish mechanic or ischemia-reperfusion (I/R)-induced injury of multiple organs, including heart, skeletal muscle, lung, kidney and skin. Importantly, MG53 acts as an E3 ligase to mediate the degradation of insulin receptor and insulin receptor substrate-1, and subsequently induces insulin resistance and metabolic diseases such as type-2 diabetes and its cardiovascular complications. In addition, MG53 negatively regulates myogenesis. As a potential therapeutic target of human diseases, multiple facets of MG53 biological function and mechanisms of action should be taken into the consideration to maximize its beneficial effects and minimize potential side-effects. Here in this review, we intend to comprehensively summarize the current progresses on the biological functions of MG53, focusing on its clinical value as a therapeutic target.
Fenfluramine and Parkinson's Disease (1977)

<h3>To the Editor.—</h3> Beasley et al (<i>Arch Neurol</i>34:255, 1977) reported that fenfluramine hydrochloride did not alter extrapyramidal signs in parkinsonian patients and concluded that "serotonin-active drugs afford no significant therapeutic benefit to patients with this disorder." They gave fenfluramine on the assumption that it would enhance serotoninergic neurotransmission by inhibiting the reuptake of serotonin or by directly stimulating postsynaptic serotonin receptors. I contend that the action of fenfluramine is too complex to permit the conclusion they reached. In contrast to agents that act simply to inhibit serotonin reuptake (fluoxetine, chlorimipramine) or to a serotonin-receptor stimulant (quipazine), which cause no change or a slight increase in serotonin concentration,<sup>1,2</sup>fenfluramine markedly decreases serotonin concentration in rat brain.<sup>3,4</sup>This decrease probably results mainly from inhibition of serotonin synthesis. Fenfluramine resembles<i>P</i>-chloroamphetamine in causing a long-lasting decrease in tryptophan hydroxylase,<sup>3</sup>the rate-limiting enzyme in serotonin
Prevention and treatment of oral mucositis following cancer chemotherapy. (1998)

The administration of many chemotherapy regimens may be complicated by toxicities that limit clinicians' abilities to deliver the most effective doses of active agents. Oral mucositis remains the dose-limiting toxicity of a variety of chemotherapeutic regimens and may result in significant morbidity, impaired nutrition, treatment delays, and dose reductions. In this report, the mechanisms of both direct and indirect stomatotoxicity are reviewed and efforts are made to help identify patient-related and treatment-related factors that predispose patients to oral mucositis. Last, various approaches to prevent and treat chemotherapy-induced mucositis are reviewed.
Idiom processing in schizophrenia: Literal implausibility saves the day for idiom priming. (2002)

Schizophrenia patients have difficulty processing nonliteral forms of discourse such as idiomatic expressions. We hypothesized that schizophrenia patients would show impaired idiom processing for literally plausible idioms (e.g., kick the bucket) but not for literally implausible idioms (e.g., be on cloud nine). Thirty-two patients and 36 controls listened to sentences containing literally plausible and implausible idioms and made lexical decisions about idiom-related or literal-related targets. Schizophrenia patients showed reduced priming for literally plausible idioms but intact priming for literally implausible idioms compared with controls. Both groups showed evidence of literal word priming. These results are consistent with the notion that schizophrenia patients make normal use of context under conditions that minimize the need for controlled processing.
In Vitro Binding Capacity of Various Fiber Sources for Magnesium, Zinc, and Copper (1995)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTIn Vitro Binding Capacity of Various Fiber Sources for Magnesium, Zinc, and CopperAhmed Idouraine, Bibi Z. Hassani, Saffiatu S. Claye, and Charles W. WeberCite this: J. Agric. Food Chem. 1995, 43, 6, 1580–1584Publication Date (Print):June 1, 1995Publication History Published online1 May 2002Published inissue 1 June 1995https://pubs.acs.org/doi/10.1021/jf00054a031https://doi.org/10.1021/jf00054a031research-articleACS PublicationsRequest reuse permissionsArticle Views154Altmetric-Citations25LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
ChemInform Abstract: Synthesis of Pyrrolizidines and l‐Oxapyrrolizidines from Proline. (1986)

Abstract Die Autoren geben einen tabellarischen Überblick über ihre Ergebnisse bezüglich der Synthesen heterocyclischer Verbindungen durch Decarboxylierung von Aminosäuren.
A abrangência do sinal wireless e o uso de aplicativos em dispositivos móveis para o transporte público em Ribeirão Preto-SP (2019)

O trabalho analisa os pontos de parada de ônibus e terminais na área de cobertura do programa de acesso wireless Ribeirão Digital, na cidade de Ribeirão Preto. Foi considerado um raio de cobertura de 100 m para captar o sinal sem fio em cada ponto de parada na região de abrangência. O mesmo procedimento de detecção de cobertura via wireless foi reproduzido em 3 smart cities brasileiras (São Paulo, Curitiba e Porto Alegre) e os respectivos pontos de parada de ônibus e terminais. Os programas de acesso ao wireless das cidades estudadas não estão relacionados à mobilidade urbana e suas facilidades de utilização de aplicativos para transportes. A pesquisa buscou relacionar serviços de transporte e comunicação a fim de conhecer a correlação das partes e mostrar um cenário no qual é necessário haver políticas de direcionamento dos sistemas de transportes para um perfil mais inteligente e sustentável.
Data communications and distributed networks (1987)

Overview of a data communications network data communications systems operations major components in a data communications sytem software and data bases transmission impairments data link controls/line protocols digital transmission distributed network architectures remote procedure calls local area netwoorks managing distributed systems design considerations.
Arginine metabolism in Saccharomyces cerevisiae: subcellular localization of the enzymes (1978)

Subcellular localization of enzymes of arginine metabolism in Saccharomyces cerevisiae was studied by partial fractionation and stepwise homogenization of spheroplast lysates. These enzymes could clearly be divided into two groups. The first group comprised the five enzymes of the acetylated compound cycle, i.e., acetylglutamate synthase, acetylglutamate kinase, acetylglutamyl-phosphate reductase, acetylornithine aminotransferase, and acetylornithine-glutamate acetyltransferase. These enzymes were exclusively particulate. Comparison with citrate synthase and cytochrome oxidase, and results from isopycnic gradient analysis, suggested that these enzymes were associated with the mitochondria. By contrast, enzymatic activities going from ornithine to arginine, i.e., arginine pathway-specific carbamoylphosphate synthetase, ornithine carbamoyltransferase, argininosuccinate synthetase, and argininosuccinate lyase, and the two first catabolic enzymes, arginase and ornithine aminotransferase, were in the "soluble" fraction of the cell.
Infected-Host-Cell Repertoire and Cellular Response in the Lung following Inhalation of<i>Francisella tularensis</i>Schu S4, LVS, or U112 (2008)

Francisella tularensis causes systemic disease in humans and other mammals, with high morbidity and mortality associated with inhalation-acquired infection. F. tularensis is a facultative intracellular pathogen, but the scope and significance of cell types infected during disease is unknown. Using flow cytometry, we identified and quantified infected-cell types and assessed the impact of infection on cell populations following inhalation of F. tularensis strains U112, LVS, and Schu S4. Initially, alveolar macrophages comprised over 70% of Schu S4- and LVS-infected cells, whereas approximately 51% and 27% of U112-infected cells were alveolar macrophages and neutrophils, respectively. After 3 days, roughly half of Schu S4- and LVS- and nearly 80% of U112-infected cells were neutrophils. All strains infected CD11b(high) macrophages, dendritic cells, monocytes, and alveolar type II cells throughout infection. Macrophage, monocyte, and dendritic-cell populations were reduced during U112 infection but not Schu S4 or LVS infection. These results demonstrate directly that F. tularensis is a promiscuous intracellular pathogen in the lung that invades and replicates within cell types ranging from migratory immune cells to structural tissue cells. However, the proportions of cell types infected and the cellular immune response evoked by the human pathogenic strain Schu S4 differ from those of the human avirulent U112.
Work in progress - Measuring the ROI&gt;inf&lt;time&gt;/inf&lt;for Static Analysis (2006)

Static analysis is one method that offers potential for reducing errors in delivered software. Static analysis is currently used to discover buffer overflows and mathematical errors, as well as verifying compliance with documented programming standards. Static analysis is routinely used in safety critical software applications within the avionics and automotive industries. Outside of these applications, static analysis is not a routinely taught method for software development. This paper intends to provide a quantitative measure for evaluating the effectiveness of static analysis as well as presenting results from an academic environment
Conventional and Non-Conventional Yeasts in Beer Production (2018)

The quality of beer relies on the activity of fermenting yeasts, not only for their good fermentation yield-efficiency, but also for their influence on beer aroma, since most of the aromatic compounds are intermediate metabolites and by-products of yeast metabolism. Beer production is a traditional process, in which Saccharomyces is the sole microbial component, and any deviation is considered a flaw. However, nowadays the brewing sector is faced with an increasing demand for innovative products, and it is diffusing the use of uncharacterized autochthonous starter cultures, spontaneous fermentation, or non-Saccharomyces starters, which leads to the production of distinctive and unusual products. Attempts to obtain products with more complex sensory characteristics have led one to prospect for non-conventional yeasts, i.e., non-Saccharomyces yeasts. These generally are characterized by low fermentation yields and are more sensitive to ethanol stress, but they provide a distinctive aroma and flavor. Furthermore, non-conventional yeasts can be used for the production of low-alcohol/non-alcoholic and light beers. This review aims to present the main findings about the role of traditional and non-conventional yeasts in brewing, demonstrating the wide choice of available yeasts, which represents a new biotechnological approach with which to target the characteristics of beer and to produce different or even totally new beer styles.
Floating absolute risk: An alternative to relative risk in survival and case‐control analysis avoiding an arbitrary reference group (1991)

We discuss the problem of describing multiple group comparisons in survival analysis using the Cox model, and in matched case-control studies. The standard method of comparing the risk in each group with a baseline group is unsatisfactory because the standard errors and confidence limits relate to correlated parameters, all dependent on precision within the baseline group. We describe the construction of standard errors for the parameters of all groups, without the need to select a baseline group. These standard errors can be regarded as relating to roughly independent parameters, so that groups can be compared efficiently without knowledge of the covariances. The method should assist in graphical presentation of relative risks, and in the combination of results from published studies. Two examples are presented.
A strategy for selecting optimal vergence pose and calibration patterns for stereo-vision calibration (2015)

The usage of stereo-vision in Automobile, Automation, machine-vision, Infotainment etc. is growing these days enormously day by day. To design a stereo-vision camera, we need to know optimal vergence pose between two cameras as well as number of stereo-pairs required for calibration so that stereo-vision can yield dense disparity map, precise 3D reconstruction, higher stereo-calibration accuracy as well as lower calibration time. This paper addresses these problems of stereo-vision prior to calibration by selecting optimal vergence pose between two cameras and optimal number of stereo-calibration pattern pairs for calibration. To estimate optimal vergence pose, a set of virtual stereo-calibrations patterns are generated by varying Euler angles and it is observed that stereo-reprojection error decreases as Roll angle reduces and exhibits mirror image property and is less sensitive to the variations in Yaw and Pitch. Also to estimate the optimal number of stereo-calibration pattern pairs, an epipolar constraint error was used in eliminating redundant pairs thereby reducing stereo-calibration time and lower stereo-reprojection error.
From Web press to Web pressure (1997)

Article From Web press to Web pressure: multimedia representations and multimedia publishing Share on Authors: Victoria Bellotti Apple Research Labs, 1 Infinite Loop, MS: 301-4A, Cupertino, CA Apple Research Labs, 1 Infinite Loop, MS: 301-4A, Cupertino, CAView Profile , Yvonne Rogers Apple Research Labs & Sussex University, Brighton BN1 9QH, UK Apple Research Labs & Sussex University, Brighton BN1 9QH, UKView Profile Authors Info & Claims CHI '97: Proceedings of the ACM SIGCHI Conference on Human factors in computing systemsMarch 1997 Pages 279–286https://doi.org/10.1145/258549.258755Online:27 March 1997Publication History 39citation859DownloadsMetricsTotal Citations39Total Downloads859Last 12 Months13Last 6 weeks1 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteGet Access
Protein Synthesis Using <i>S</i>-Alkyl Thioester of Partially Protected Peptide Segments. Synthesis of DNA-Binding Protein of <i>Bacillus stearothermophilus</i> (1992)

Abstract Using partially protected peptide thioesters as building blocks, we synthesized HU-type DNA-binding protein of Bacillus stearothermophilus. Four peptide segments, Boc–[Lys(Boc)3]–HBs(1–15)–SCH2CH2CONH2, iNoc–[Lys(Boc)18,19,23,38]–HBs(16–39)–SCH2CH2CONH2, iNoc–[Lys(Boc)41,59]–HBs(40–60)–SCH2CH2CONH2, [Lys(Boc)75,80,83,86,90]–HBs(61–90) were prepared using peptides obtained by a solid-phase method. A partially protected peptide thioester was condensed to a peptide with a free amino group by converting the thioester to the corresponding active ester in the presence of silver ions and N-hydroxysuccinimide. Finally, highly pure synthetic HBs(1–90) was obtained.
Recent Head Damage Awards (1961)

Head trauma is responsible for more litigation than any other single bodily mechanical damage. Belli ranks brain injuries second only to the back and spine in producing permanent and crippling disabilities.
Geographical evolution of the CTX-M -lactamase an update (2007)

The CTX-M- type extended spectrum -lactamases (ESBLs) that preferentially hydrolyze cefotaxime are emerging globally and comprise of more than 50 enzymes. The emergence of novel CTX-M - lactamases in several countries is noted as opposed to the transfer of established CTX-M genes from one country to another, suggestive of a de novo dissemination of CTX-M genes.
Embedded cryptographic hardware : design & security (2005)

Compact and Efficient Encryption/Decryption Module for FPGA Implementation of AES PAX: A Datapath-Scalable Minimalist Cryptographic Processor For Mobile Devices Architectural Design Features of a Programmable High Throughput AES Coprocessor Power-Analysis Attack on an ASIC AES Implementation On the Importance of Protecting c in SFLASH against Side Channel Attacks Resistance Against Power and Timing Attacks: An Evaluation of Two Clock-less Implementations of the AES Modular Multiplication: Methods and Hardware A Design of Basis-Independent Bit-Parallel Multipliers Reducing the Complexity of Modular Multiplication by Modification of One Operand Special Hyperelliptic Curve Cryptosystems of Genus Two: Efficient Arithmetic and Fast Implementation A Generic Coprocessor For Elliptic Curve Scalar Multiplication on Hardware Hyperelliptic Curve Cryptosystem: What is the Best Parallel Hardware Architecture? Permutation Operations in Block Ciphers Streaming Encryption for a Secure Wavelength and Time Domain Hopped Optical Network Bibliography Index.