gebhart/patrepeval huggingface dataset:
Scale adaptive visual tracking with latent SVM (2014)

A scale adaptive visual tracking algorithm based on the latent support vector machine (SVM) is proposed. The location of the object to be tracked is predicted by scanning all possible candidate locations and the scale is treated as a latent variable. With the predicted location, the latent SVM is optimised by a coordinate descent approach that optimises the latent variable and SVM parameters in an iterative manner. The separation of location and scale searching makes the tracker less likely to drift. Experimental results on test video sequences demonstrate that the proposed approach shows better accuracy than several state‐of‐the‐art visual tracking algorithms.
Non-metallic inclusions in steels – origin and control (2018)

Non-metallic inclusions (NMIs) play a key role in many important properties of steel, influencing both processing and application of steel products. In this work, the current understanding of the origin and classification of NMIs is reviewed, highlighting the dramatic development of the last decades. This includes the discussion of the thermodynamics of inclusion formation and the current knowledge on the effects of melt shop processing variable on NMIs composition, amount and size distribution. The development of inclusion engineering – tailoring the process to obtain the desired NMIs is highlighted and the development in selected areas – tire cord, springs and bearing steels as well as prevention of nozzle clogging – is used to illustrate this development. The promising field of “oxide metallurgy” is also discussed in the context of inclusion engineering. Finally, the difficulties in meaningfully characterizing and quantifying NMIs are briefly commented. In summary it is concluded that inclusion control in steels has evolved significantly in the last decades. This is due to the progress in understanding the interplay between thermodynamics, steel and slag chemical composition as well as melt shop processing. This made possible the tailoring of non-metallic inclusions via processing, to optimize steel properties. Nonetheless, some important problems remain and must still be solved to improve inclusion control and optimization.
A Hybrid Semantic Item Model for Recipe Search by Example (2010)

As a necessary part of our daily life, choose what dishes to cook that is a problem and troubles many people every day. In recent years, there has been a proliferation of multimedia recipe data on the Web 2.0 communities. To assist people to navigate and search on from large amounts of recipes, a suitable recipe model is crucial and indispensable. However, recipes have some distinct characteristics that conventional data models are inadequate to represent them for such data. For example, it is unreasonable and insufficient to measure how similar the cooking procedures of two dishes are only through text descriptions and/or their extracted terms. The main reason is that this raw data (or low-level features extracted from the raw data, e.g. term for text, color for image) do not map to the high-level semantics readily. In this paper, we argue that a recipe model should be semantic-based and behavior-oriented, preferably with domain knowledge support. A hybrid semantic item (HSI) model is next presented for addressing this problem. Based on HSI model, we devise a corresponding approach for recipe search by example. The experiment on our multimedia recipe retrieval system demonstrates that our HSI approach outperforms baseline methods.
Multimodal affective driver interfaces for future cars (2002)

In this paper, we uncover a new potential application for multimedia technologies: car interfaces for enhanced driver's safety. We also describe the experiment we conducted in order to map certain physiological signals (galvanic skin response, heart beat, and temperature) to certain emotions (Neutral, Anger, Fear, Sadness, and Frustration). We demonstrate the results we gained and describe how we use these results to our Multimodal Affective Driver Interface for the drivers of the future cars.
The effects of synthetic glucagon fragments on glucose-6-phosphate dehydrogenase. II. (1979)

The glucagon fragment H-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr-OH (positions 22-29) was synthesized by a conventional method. Two glucagon fragments, H-His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-OH (positions 1-14) and the octapeptide fragment synthesized in this study were tested for inhibitory activity towards glucose-6-phosphate dehydrogenase. The octapeptide (positions 22-29) inhibited glucose-6-phosphate dehydrogenase activity by 18% at a concentration of 0.5 mg/ml.
Privacy preserving data mining for social networks (2014)

Advances in technology have made it possible to collect personal and professional data about individuals and the connections between them, such as their email correspondence and friendships on the internet. Many agencies and researchers who have collected such social network data often have a compelling interest in allowing others to analyze the data. However, in many cases the social network data describes relationships that are private and sharing the data for analysis can result in unacceptable disclosures. Online Social Networks, such as Facebook, are increasingly utilized by many users today. These networks allow users to publish details about themselves and to connect to their friends. Most of the information revealed inside these networks is not private. Yet it is possible to use learning algorithms on released data to predict private information from public information. This paper focuses on the problem of private information leakage from the information present on the social networks. The main topic of the presented effort is the representation of the cause-effect relationships within social network data by the application of the soft computing technique of fuzzy Inference Systems. Also, sanitization techniques that could be used in various situations are suggested and effectiveness of these sanitization techniques is analyzed.
Prolonged, granulocyte–macrophage colony-stimulating factor-dependent, neutrophil survival following rheumatoid synovial fibroblast activation by IL-17 and TNFalpha (2008)

The increased number of neutrophils with an extended lifespan found in the rheumatoid synovial microenvironment is partly accounted for by IL-17 and TNFalpha activation of synovial fibroblasts. TH17-expressing T cells within the rheumatoid synovium are likely to contribute significantly to this effect.
Molecular Characterization of PDGFR‐<i>α</i>/PDGF‐A and c‐KIT/SCF in Gliosarcomas (2005)

Gliosarcomas are rare and poorly characterized malignant brain tumors that exhibit a biphasic tissue pattern with areas of gliomatous and sarcomatous differentiation. These tumors are histological variants of glioblastoma, displaying a similar genetic profile and dismal prognosis. Up-regulation of PDGFR subfamily of tyrosine kinase members, PDGFR-alpha and c-Kit, and their intracellular effectors RAS/RAF/MAPK has a crucial role in the cancer development. In addition, signal transduction mediated by activating mutations of c-Kit and PDGFR can be effectively blocked by specific tyrosine kinase inhibitors, such as Imatinib mesylate. The aim of this study was to characterize the molecular alterations of PDGFR signaling in gliosarcomas. Six cases were analyzed by immunohistochemistry for the expression of PDGFR-alpha, c-Kit and their ligands PDGF-A and SCF, respectively. The cases were further evaluated for the presence of activating mutations of PDGFR-alpha (exons 12 and 18) and c-kit (exons 9, 11, 13, and 17), as well as B-RAF (exons 11 and 15). Expression of PDGF-A was found in all cases and co-expression of PDGFR-alpha was observed in three cases. Four cases showed expression of SCF, and c-Kit was observed only in one case that also expressed SCF. Generally, immunoreaction predominates in the glial component. The mutational analysis of PDGFR-alpha showed the presence of an IVS17-50insT intronic insertion in two cases, one of them also with a 2472C > T silent mutation; this silent mutation was also found in another case. Glioma cell line analysis of IVS17-50insT insertion showed no influence on PDGFR-alpha gene splicing. No mutations were detected in c-kit and B-RAF oncogenes. Our results indicate that activating mutations of PDGFR-alpha, c-kit and B-RAF are absent in gliosarcomas. Nevertheless, the presence of a PDGFR-a/PDGFA and c-Kit/SCF autocrine/paracrine stimulation loop in a proportion of cases, supports the potential role of specific tyrosine kinase inhibitors in the treatment of gliosarcomas.
A systematic comparison of combination DMARD therapy and tumour necrosis inhibitor therapy with methotrexate in patients with early rheumatoid arthritis (2009)

In early active RA, both combination DMARDs and TNF/MTX are more effective than MTX monotherapy. DMARD and TNF/MTX combinations had equal efficacy on ACR response, withdrawals for inefficacy, disability and erosive progression. There is an apparent advantage for TNF/MTX combinations in the effect on toxicity with fewer consequent patients. We conclude that there is strong evidence in favour of combination treatment for RA but there is still uncertainty about which regimen is preferable.
Optical, chemical and mechanical modifications induced by ion implantation on glass surfaces (1982)

Abstract Soda-lime glasses have been implanted with 50 keV Az ions. Modifications induced on the glass surface have been studied as a function of implanted dose, with particular regard to optical, chemical and mechanical properties. Optical measurements indicate a reduction of the refractive index, connected to the surface sodium content. The sodium profile has been measured using the Na23(p, α)Ne20 nuclear reaction. An improvement of the mechanical resistance has been observed at low implantation dose, together with a change of the chemical durability. An expansion of glass has been observed by S.E.M. and interpherometric microscopy for 80 keV implantation energy.
Thermodynamic stability and electronic structure of η-Ni6Nb(Al,Ti) from first principles (2014)

First principles calculations in combination with special quasirandom structures are used to investigate the thermodynamic stability and electronic structure of a partially ordered hexagonal phase with chemistry Ni6Nb(Al,Ti) observed in Allvac 718Plus. The results agree with the experimental observations by confirming the structural stability of the alloy over a wide range of compositions. At finite temperature, vibrational and configurational contributions to the free energy stabilize a competing orthorhombic phase, which is shown to become energetically favourable for high Ti concentrations.
A graphical query language for object-oriented data models (2002)

A graphical, functional query language, called Tabletalk, which can be used for a variety of object-oriented data models is described. Tabletalk expresses queries as mosaics, where spatial juxtaposition encodes the application of the functional combinators. Tabletalk is presented as a user-oriented and generic interface for object-oriented data models.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Effektivität intramuskulär verabreichten Cytosin-Arabinosids bei der ambulanten Behandlung von Kindern mit akuter Leukämie in Remission (1980)

Investigation was done in children with acute leukemia in complete hematological remission. It was tested whether out-patient treatment by intramuscular administration of arabinosylcytosine (Ara-C) may obviate the continuous intravenous Ara-C regimen. Every therapy cycle lasted 5 days. Changes in peripheral blood cell counts after 5 days of continuous intravenous. Ara-C infusion against 5 days of intramuscular Ara-C application given every 12 h were tested. 129 cycles of intramuscular application and 11 cycles of intravenous application were evaluated. Evaluation was done by the Friedmanntest. There was a significant decrease in blood cell counts after intramuscular Ara-C treatment. When administered intramuscularly during the first cycle Ara-C was effective for at least 3 weeks, whereas after repeated cycles the decline of blood cells was only demonstrable for 14 days. A comparison of the effect between intravenous and intramuscular routes revealed similar results. No local side effects were noted when Ara-C was given intramuscularly.
Advanced FDM systems technologies (1993)

Frequency-division multiplexing (FDM) and frequency reuse (FR) technologies provide the means for realizing large-size high-bit-rate optical networks. New optical components have been recently developed for realizing this possibility. One of these components is a fast tunable laser1 using a single tuning current to access a set of equally spaced frequencies. In addition, the laser can be randomly switched among these frequencies in a few nanoseconds. Figure 1 shows the tuning curve of such a laser. As important, the same combination of frequencies can be obtained from a large number of identical lasers fabricated simultaneously. This greatly simplifies the implementation of FDM networks based on tunable transmitters and frequency routing.2
Phytochemicals in the Control of Human Appetite and Body Weight (2010)

Since obesity has grown to epidemic proportions, its effective management is a very important clinical issue. Despite the great amount of scientific effort that has been put into understanding the mechanisms that lead to overconsumption and overweight, at the moment very few approaches to weight management are effective in the long term. On the other hand, modern society is also affected by the growing incidence of eating disorders on the other side of the spectrum such as anorexia and bulimia nervosa which are equally difficult to treat. This review will try to summarise the main findings available in the literature regarding the effect of plants or plant extracts (phytochemicals) on human appetite and body weight. The majority of plant extracts are not single compounds but rather a mixture of different molecules, therefore their mechanism of action usually targets several systems. In addition, since some cellular receptors tend to be widely distributed, sometimes a single molecule can have a widespread effect. This review will attempt to describe the main phytochemicals that have been suggested to affect the homeostatic mechanisms that influence intake and body weight. Clinical data will be summarised and scientific evidence will be reviewed.
State-of-the-Art Overview on Data Mining in Power Systems (2006)

This paper presents an overview on applications of data mining to power systems. DM plays an important role to extract rules or knowledge through database. Power systems have complicated characteristics due to the nonlinearity. To grasp the nonlinear relationship between input and output variables, the data mining techniques help power system operators to smooth power system operation and planning. In this paper, they are overviewed from a standpoint of methodologies and applications
Theaflavins from Black Tea, Especially Theaflavin-3-gallate, Reduce the Incorporation of Cholesterol into Mixed Micelles (2008)

Tea is one of the most widely consumed beverages in the world and may be associated with reduced heart disease rates. Theaflavins, which are formed in the production of black tea, have been suggested being responsible for the blood-cholesterol-lowering (BCL) effects of tea. We hypothesized that the effect of theaflavins on BCL could be through interference in the formation of dietary mixed micelles, which could result in reduced intestinal cholesterol absorption. Micelles were produced by mixing oleic acid, bile acids, lyso-phosphatidylcholine, and cholesterol. Theaflavin-treated micelles/particles were analyzed using electron microscopy (cryo-TEM), high-performance liquid chromatography (HPLC) analysis, and light-scattering particle size measurements. A dose-dependent inhibitory effect of theaflavins on the incorporation of (14)C-labeled cholesterol into micelles and a theaflavin-dependent increase in particle size was found. These particles consisted of insoluble large multilamellar vesicles with onion-like structures. Ultracentrifugation and HPLC analysis revealed that the pellets contained mainly theaflavin-3-gallate, while the remaining theaflavins were found to be present in the supernatant. Using purified theaflavin subtypes confirmed that mainly theaflavin-3-gallate is responsible for multilamellar vesicle formation. These results show that theaflavins can play a role in decreased intestinal cholesterol absorption via inhibition of micelle formation.
Atlas-Based Fuzzy Connectedness Segmentation and Intensity Nonuniformity Correction Applied to Brain MRI (2006)

A framework that combines atlas registration, fuzzy connectedness (FC) segmentation, and parametric bias field correction (PABIC) is proposed for the automatic segmentation of brain magnetic resonance imaging (MRI). First, the atlas is registered onto the MRI to initialize the following FC segmentation. Original techniques are proposed to estimate necessary initial parameters of FC segmentation. Further, the result of the FC segmentation is utilized to initialize a following PABIC algorithm. Finally, we re-apply the FC technique on the PABIC corrected MRI to get the final segmentation. Thus, we avoid expert human intervention and provide a fully automatic method for brain MRI segmentation. Experiments on both simulated and real MRI images demonstrate the validity of the method, as well as the limitation of the method. Being a fully automatic method, it is expected to find wide applications, such as three-dimensional visualization, radiation therapy planning, and medical database construction.
Caffeine Overdose with Rhabdomyolysis and Hypokalaemia (2007)

Caffeine, a normal content of various beverages and over the counter medications, taken in higher doses can cause serious toxicity. Complications like rhabdomyolysis and acute renal failure, which are life threatening, are reversible if diagnosed early and treated appropriately. Caffeine toxicity can also cause serious hypokalaemia, which needs prompt correction. Here we present a patient with caffeine toxicity complicated by rhabdomyolysis and acute renal failure who made a complete recovery.
Treatment of acute otitis media: a controlled study of 142 children. (1970)

Results of the use of ampicillin, penicillin G and symptomatic therapy in the treatment of acute otitis media in 142 children were compared. Antibiotic therapy conveyed significant benefit. No major differences were observed between penicillin and ampicillin, except in the age group under 3 years where ampicillin was associated with the best results. Ampicillin appears to be the drug of choice. Its superiority over symptomatic therapy was statistically significant. Long-term sequelae were not observed in any of the three treatment groups. The relative merits of erythromycin and ampicillin require further study.
Therapeutic Suppression of Nonsense Mutation: An Emerging Target in Multiple Diseases and Thrombotic Disorders (2017)

Nonsense mutations contribute to approximately 10-30% of the total human inherited diseases via disruption of protein translation. If any of the three termination codons (UGA, UAG and UAA) emerges prematurely [known as premature termination codon (PTC)] before the natural canonical stop codon, truncated nonfunctional proteins or proteins with deleterious loss or gain-of-function activities are synthesized, followed by the development of nonsense mutation-mediated diseases. In the past decade, PTC-associated diseases captured much attention in biomedical research, especially as molecular therapeutic targets via nonsense suppression (i.e. translational readthrough) regimens. In this review, we highlighted different treatment strategies of PTC targeting readthrough therapeutics including the use of aminoglycosides, ataluren (formerly known as PTC124), suppressor tRNAs, nonsense-mediated mRNA decay, pseudouridylation and CRISPR/Cas9 system to treat PTC-mediated diseases. In addition, as thrombotic disorders are a group of disease with major burdens worldwide, 19 potential genes containing a total of 705 PTCs that cause 21 thrombotic disorders have been listed based on the data reanalysis from the 'GeneCards® - Human Gene Database' and 'Human Gene Mutation Database' (HGMD®). These PTC-containing genes can be potential targets amenable for different readthrough therapeutic strategies in the future.
A Microinjector Free of Satellite Drops and Characterization of the Ejected Droplets (1998)

Abstract This paper presents the droplet characteristics of a newly developed thermally driven microinjector, which uses asymmetric bubbles to increase the injection frequency significantly. Through special heater and chamber design, bubbles are generated to surround the nozzle in such a way to cut off the droplet tail and eliminate satellite droplets. Visualization systems are developed to verify the droplet ejection free of satellite droplets and to characterize the ejection and trajectory. A simple Stokes-flow model is also used to estimate the droplet ejection trajectory.
Engineering nanofibers for a novel intradermal vaccination method for whooping cough (2010)

Current delivery systems for vaccines present major logistical problems when large populations need to be vaccinated within a short time period, such as in the case of a pandemic. An efficient and effective method for pandemic vaccination is the driving force of the research performed by our group. The proposed alternative vaccination technique consists of a self-administrable patch made of electrospun nanofibers, where antigens and adjuvants are imbedded during the electrospinning process. This allows large quantities of immunogens to be encapsulated within the nanofibrous mat. This abstract describes the use of the electrospinning technique for the development of a new intradermal delivery system for biologically functional pertussis toxin (PT) to effectively vaccinate against whooping cough. The functional PT was immobilized within highly hygroscopic polyvinyl pyrrolidone (PVP) nanofibers. To establish the efficiency of the technique to immobilize biologically functional PT, prepared patches were incubated with Chinese Hamster Ovary (CHO, K1) cells. The cellular assay measures the degree of clumping of the natively attached CHO cells upon exposure to biologically functional PT. The simultaneous incubation of diluted stock and electrospun PT allowed for a direct comparison of functional PT concentration. This study has reproducibly demonstrated that approximately 80% of the total PT added to the polymer solution was successfully incorporated into the electrospun mat, and maintained biological functionality.