gebhart/patrepeval huggingface dataset:
Synthesis of ring-substituted derivatives of cyclopentadienyl tricarbonyl complexes of molybdenum and tungsten (1980)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSynthesis of ring-substituted derivatives of cyclopentadienyl tricarbonyl complexes of molybdenum and tungstenA. Chaloyard and N. El MurrCite this: Inorg. Chem. 1980, 19, 11, 3217–3220Publication Date (Print):November 1, 1980Publication History Published online1 May 2002Published inissue 1 November 1980https://pubs.acs.org/doi/10.1021/ic50213a003https://doi.org/10.1021/ic50213a003research-articleACS PublicationsRequest reuse permissionsArticle Views166Altmetric-Citations18LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Theory of Electronic States and Transport in Graded Mixed Semiconductors (1969)

Semiconductors which are slowly graded in composition can be shown to have position-dependent band gaps and position-dependent effective masses, describable in terms of an effective Hamiltonian in an effective-mass equation. The effective Hamiltonian previously obtained is, in the present work, rendered Hermitian. Electronic minority-carrier transport for graded systems is described in terms of an effective field which includes the electrostatic field plus a term in the gradient of the band edge and another in the gradient of the effective mass. The local radiative-recombination lifetime and local density of states for inhomogeneous semiconductors are discussed. The equation for the excess minority-carrier concentration in an inhomogeneous semiconductor is deduced and is found to differ from that in an homogeneous system, by the effective field replacing the electric field, by the position dependences of lifetime and mobility, and by terms in the mobility gradient. Some phenomena specific to graded mixed semiconductors are considered on the basis of the theoretical analysis.
A first principles study of water dissociation on small copper clusters (2010)

Water dissociation on copper is one of the rate-limiting steps in the water-gas-shift (WGS) reaction. Copper atoms dispersed evenly from freshly made catalyst segregate to form clusters under the WGS operating conditions. Using density functional theory, we have examined water adsorption and dissociation on the smallest stable 3-dimensional copper cluster, Cu(7). Water molecules are adsorbed on the cluster sequentially until full saturation at which no direct water-copper contact is sterically possible. The adsorption is driven mainly by the overlap between the p-orbital of O atom occupied by the lone pair and the 3d-orbitals of copper, from which a fractional charge is promoted to the 4s-orbital to accommodate the charge transfer from water. Water dissociation on the Cu(7) cluster was investigated at both low and high water coverage. It was found that water dissociation into OH and H is exothermic but is inherently a high temperature process at low coverage. At high coverage, the reaction becomes more exothermic with fast kinetics. In both cases, water can catalyze the reaction. It was found that direct dissociation of the OH species is endothermic with a significantly higher barrier at both low and high coverage. However, the OH species can readily react with another adjacent hydroxyl group to form an O adatom and water molecule. Our studies indicate that the basic chemical properties of water dissociative chemisorption may not change significantly with the size of small copper clusters. Similarities between water dissociation on copper clusters and on copper crystalline surfaces are discussed.
A NEW PERSONALIZED LEARNING PATH GENERATION METHOD: ACO-MAP (2014)

Personalized curriculum sequencing is an important issue to achieve learning goal especially in e-learning systems. The main challenge of the traditional teaching system is providing courses suitable to different learners with different knowledge background. Therefore, many researchers developed adaptive learning path systems in order to promote the effectiveness and performance of learning process. Furthermore, an optimal adaptive learning path can help the learners in reducing the cognitive overload and disorientation. In this paper, a novel two stages adaptive learning path algorithm, which is called ACO-Map is proposed. Discovering groups of learners according to their knowledge patterns is performed based on the results of pre-test, in first stage. Then in second stage ant colony optimization as a metaheuristic method is applied to find a learning path based on Ausubel Meaningful Learning Theory. The investigation emphasizes the association between the learning content and the knowledge level of each learner in adaptive learning. The output of this algorithm is an adaptive learning path for each group of learners according to their needs.
A calibration-free 800MHz fractional-N digital PLL with embedded TDC (2010)

An 800 MHz digital PLL with its TDC embedded within the DVCO is implemented in 65 nm CMOS and occupies 0.027 mm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> . The design requires no calibration and achieves the fractional-N operation without a multi-modulus feedback divider. To further improve the TDC linearity, mismatch filtering is used to achieve a DNL of less than 3.5% of LSB.
Distribution and Organoleptic Impact of Ethyl 3-Hydroxybutanoate Enantiomers in Wine (2015)

Enantiomers of ethyl 3-hydroxybutanoate were assayed in 87 commercial wines from various vintages and origins, using chiral gas chromatography (β-cyclodextrin). Generally, ethyl 3-hydroxybutanoate levels were higher in red than in white wines of the same age. The average S/R enantiomeric ratio of this compound in red wine was approximately 75:25 (± 13), with an average total concentration of ∼ 450 (± 150) μg/L. In red wines, R-form levels increased gradually during aging, but no variations were observed in S-form concentrations. To our knowledge, no previous research had determined the enantiomeric distribution of this compound in wine. The olfactory threshold of the S-form in dilute alcohol solution was 21 mg/L, one-third that of the R-form: 63 mg/L. The S- and R-forms had different aromatic nuances. The olfactory threshold of their mixture (85:15, m/m) was 14 mg/L, indicating a simple additive effect in this binary mixture. Furthermore, the concentrations found in red wines were considerably below the olfactory threshold under the same experimental conditions. Sensory analysis revealed that ethyl 3-hydroxybutanoate (S/R, 85:15, m/m) had an enhancing effect on the perception of fruity aromas in the matrices studied. Sensory profiles highlighted the contribution of ethyl 3-hydroxybutanoate to red-berry and fresh-fruit descriptors, despite its subthreshold concentrations.
Apigenin inhibits UVA-induced cytotoxicity in vitro and prevents signs of skin aging in vivo (2016)

Apigenin (4',5,7-trihydroxyflavone) is a flavone that has been reported to have anti-inflammatory, antioxidant and anti-carcinogenic properties. In this study, we investigated the protective effects of apigenin on skin and found that, in experiments using cells, apigenin restored the viability of normal human dermal fibroblasts (nHDFs), which had been decreased by exposure to ultraviolet (UV) radiation in the UVA range. Using a senescence-associated (SA)-β-gal assay, we also demonstrate that apigenin protects against the UVA-induced senescence of nHDFs. Furthermore, we found that apigenin decreased the expression of the collagenase, matrix metalloproteinase (MMP)-1, in UVA-irradiated nHDFs. UVA, which has been previously identified as a photoaging-inducing factor, has been shown to induce MMP-1 expression. The elevated expression of MMP-1 impairs the collagen matrix, leading to the loss of elasticity and skin dryness. Therefore, we examined the clinical efficacy of apigenin on aged skin, using an apigenin‑containing cream for clinical application. Specifically, we measured dermal density, skin elasticity and the length of fine wrinkles in subjects treated with apigenin cream or the control cream without apigenin. Additionally, we investigated the effects of the apigenin-containing cream on skin texture, moisture and transepidermal water loss (TEWL). From these experiments, we found that the apigenin‑containing cream increased dermal density and elasticity, and reduced fine wrinkle length. It also improved skin evenness, moisture content and TEWL. These results clearly demonstrate the biological effects of apigenin, demonstrating both its cellular and clinical efficacy, and suggest that this compound holds promise as an anti-aging cosmetic ingredient.
CO2 capture using monoethanolamine solutions : development and validation of a process model based on the SAFT-VR equation of state (2013)

The development of a predictive model for an absorber-desorber process for the separation of carbon dioxide (CO2) from a gas stream using an aqueous alkanolamine solution as a solvent is presented. Post-combustion carbon dioxide capture by absorption with aqueous amine solvents is likely to play an important role in climate change mitigation, by helping to reduce a significant fraction of CO2 emissions from fossil fuel power plants. There are, however, a number of concerns with the large scale deployment of this technology, including energy requirements, solvent degradation and the environmental and health impact resulting from a potential loss of solvent and solvent degradation products. Modelling studies can play an invaluable and complementary role in addressing some of these issues, including the choice of solvent and operating conditions that yield optimal performance. The model presented here incorporates state-of-the-art SAFT-VR thermodynamics into a rate-based process model. A characteristic of the proposed approach is that all the reactions are treated within a thermodynamic description, assuming chemical equilibrium throughout. This greatly reduces the amount of experimental data required to model the behaviour of the absorber. Furthermore, in contrast with many treatments of reactive systems of this type, no enhancement factor is used in the process model. The absorber-desorber process model is implemented in the gPROMS software platform and validated using published pilot plant experimental data for the removal of CO2 from an air and CO2 stream using monoethanolamine (MEA) solutions. A scaling of the diffusivity in the liquid phase, that is found to be transferable to different operating conditions, is proposed. Reliable predictions are obtained for the temperature and composition profiles in the gas and liquid phases, including a good description of the temperature bulge which sometimes appears along the height of the absorber column. The same transferable model is used to describe both the absorber and the desorber columns. The influence of key parameters of the model for different operating conditions is assessed through a sensitivity analysis. The model developed in this study is applied to simulate a complete amine-based carbon capture absorber-desorber process. Given the relatively simple modelling of the solvent/CO2 interactions, in which the reactions are treated implicitly through a physical approach, the proposed model lends itself well to the investigation of other solvents.
Face to Face (1977)

Following graduation from Manhattan College with a Bachelor of Civil Engrg. degree and graduate studies in sanitary engineering at Virginia Polytechnic Inst. & State Univ., James J. Corbalis Jr. began what was to become a notable career in the water‐supply f ield. His first employment was with Wiley& Wilson, Consulting Engineers, in Lynchburg, Va., as a design engineer. He later became a sanitation of f icer for the Virginia State Dept. of Health, followed by a position as sanitary engineer for the County of Fairfax (Virginia.) During WWII he served as an ensign with the US Navy, Civil Engrg. corps. After being discharged, he became a Consulting engineer for the Fairfax County Planning Com., then sanitary engineer for the County of Fairfax, and later engineer‐director for the City of Alexandria San. Auth. He presently is engineer‐director for the Fairfax County Water Auth. Mr. Corbalis has a long list of professional affiliations which include: certified professional engr. (Civil), Virginia; honorary member, AWWA; diplomate, American Academy of Envir. Engrs.; member and past President, Virginia Soc. of Professional Engrs.; member and pastdirector. Natl. Soc. of Professional Engrs.; member and past chairman, Virginia Sect., AWWA; member and past President, Virginia Water Pollution Control Assn.; and member and past President, Virginia Water Pollution Control Assn.; and member and past President, Virginia Water and Sewer Auths. Assn. He is also a member of the Interstate Com. on the Potomac River Basin, and a member of the Technical Advisory Com., Water Resources Planning Bd., Metropolitan Washington Council of Governments. In the following article, AWWA Exec. Dir. Eric Johnson questions Mr. Corbalis about the Fairfax County Water Auth. covering such topics as the formation of the authority, discussion of their Operations, water rights, rate setting, public relations efforts, and labor‐management relations.
Sentinel lymph node identification in breast cancer patients. (2002)

In agreement with previous studies, our results showed that sentinel lymph node radioguided biopsy is a simple and reliable method for predicting axillary lymph nodes status and for avoiding axillary dissection in early breast cancer patients with sentinel node free of metastases.
Training Neural Networks Without Gradients: A Scalable ADMM Approach (2016)

With the growing importance of large network models and enormous training datasets, GPUs have become increasingly necessary to train neural networks. This is largely because conventional optimization algorithms rely on stochastic gradient methods that don't scale well to large numbers of cores in a cluster setting. Furthermore, the convergence of all gradient methods, including batch methods, suffers from common problems like saturation effects, poor conditioning, and saddle points. This paper explores an unconventional training method that uses alternating direction methods and Bregman iteration to train networks without gradient descent steps. The proposed method reduces the network training problem to a sequence of minimization sub-steps that can each be solved globally in closed form. The proposed method is advantageous because it avoids many of the caveats that make gradient methods slow on highly non-convex problems. The method exhibits strong scaling in the distributed setting, yielding linear speedups even when split over thousands of cores.
Preparation and characterization of novel elastin‐like polypeptide‐collagen composites (2013)

Collagen-based biomaterials suffer from poor mechanical properties and rapid degradation. Elastin-like polypeptides (ELPs) possess good biocompatibility and have unique solution properties that allow them to coacervate above a critical temperature. The objective of this research was to prepare a series of freeze dried ELP-collagen composite scaffolds as a proof of concept. Combination of ELP and collagen has the potential to produce composite structures with varying strengths. Four different composite structures were prepared by varying the ratio of ELP to collagen. Increased ELP content in the scaffolds appears to have reduced the residual water content based on Fourier transformed infrared spectroscopy and differential scanning calorimetry. Scanning electron microscopy images of ELP-collagen composites showed a three-dimensional, open porous structure with the formation of characteristic aggregates of ELP. The mechanical testing experiments showed that the elastic modulus, tensile strength, and toughness of ELP-collagen scaffolds were significantly greater than neat collagen scaffolds. The improved mechanical properties were attributed to a homogeneous network structure with additional reinforcement coming from the ELP aggregates. Our study confirms that ELP-collagen composites with superior physical and mechanical properties compared to collagen scaffolds can be produced. Further optimization of design parameters will allow producing ELP-collagen composites for specific biomedical applications.
The Structure and Bonding of Cyclopentadienylthallium and Bis-cyclopentadienylmagnesium (1958)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe Structure and Bonding of Cyclopentadienylthallium and Bis-cyclopentadienylmagnesiumF. A. Cotton and L. T. ReynoldsCite this: J. Am. Chem. Soc. 1958, 80, 2, 269–273Publication Date (Print):January 1, 1958Publication History Published online1 May 2002Published inissue 1 January 1958https://pubs.acs.org/doi/10.1021/ja01535a004https://doi.org/10.1021/ja01535a004research-articleACS PublicationsRequest reuse permissionsArticle Views388Altmetric-Citations74LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
[Construction of a cDNA library of Schistosoma japonicum]. (1990)

The template mRNA was extracted from Schistosoma japonicum. The first strand of cDNA was synthesized by AMV-reverse transcriptase. The second strand cDNA was first digested by RNase H to remove mRNA and was then synthesized by AMV-reverse transcriptase, T4-DNA polymerase. Sizing of cDNA was applied on a NACS column to remove small fragments of less than 1 kb. Homopolymeric tailing of vector (pUC18) was done with dGTP and DNA terminal transferase and tailing of the cDNA with dCTP was carried out under the same conditions. After annealing, the plasmids with cDNA were transformed into E. coli MC1061. The efficiency of cloning was about 10(4)/micrograms mRNA with 30% of the transformants having the inserts of cDNA (Figs. 1-2).
WHEY PROTEIN CONCENTRATES IN A PROCESSED MEAT LOAF (1980)

ABSTRACT Processed meat loaves were prepared with dry whey, and ultrafiltrated whey protein concentrates containing 18.7% (WPC‐1520) and 32.5% (WPC‐3035) protein, along with a control containing nonfat dry milk (NDM). Binding strength; as measured by Instron shear, and tenderness, as evaluated by a taste panel, of the NDM and three whey treatments were not different. A taste panel, using the triangle test, could not differentiate the NDM and WPC‐1520 (P > 0.05), but did differentiate all other comparisons (P < 0.05). Higher sensory panel ratings for flavor were given to samples containing dry whey (P < 0.05), possibly because of flavor enhancement resulting from the high level of lactose contributed by dry whey. Similarly more desirable juiciness ratings by the panel given to samples containing WPC‐3035 (P<0.05) may possibly be attributed to the water‐binding characteristics of the high levels of whey protein.
Intensive Care — is it Possible in a Private Hospital? (1984)

Although sophisticated intensive care units have become universal in major public hospitals in Australia, this complex and expensive form of patient care is usually not available in independent private hospitals. Such a unit was recently established in a large private hospital which had expanded its facilities to encourage major surgery and its admission policies to include complex specialist medical problems. The unit's organisation included an appropriate physical area, comprehensive equipment, skilled nursing staff, resident medical staff, accredited medical specialists, and a common set of policies and protocols. In its first 12 months, the unit had 301 admissions, 82% of whom were surgical. Unit mortality was 3.3% and hospital mortality 6%. Patients were similar in age and sex distribution to those admitted to an intensive care unit in a public hospital but their numbers, type of illness, duration of admission and mortality differed. Despite the feasibility of establishing a sophisticated intensive care unit in a private hospital, there were potential problems related to staffing (especially insufficient numbers of trained nurses), funding (especially inadequacy of hospital and medical insurance and unavailability of many drugs on the Government's Schedule of Pharmaceutical Benefits) and relations with medical staff outside the unit.
A Phase II Trial of Cardioprotection with Cardioxane (ICRF-187) in Patients with Advanced Breast Cancer Receiving 5-Fluorouracil, Doxorubicin and Cyclophosphamide (1995)

From January 1991 to August 1993, 237 women with metastatic breast cancer were recruited into a multicentric phase II clinical trial designed to assess the cardioprotective activity of Cardioxane (ICRF-187). All patients were treated with 5-fluorouracil 500 mg/m2, doxorubicin 50 mg/m2, cyclophosphamide 500 mg/m2 (FDC) and Cardioxane 1000 mg/m2, in cycles repeated every 3-4 weeks. Cardiac functions were assessed at baseline by physical examination, ECG, and resting ultrasound left ventricle ejection fraction (LVEF). The same tests were repeated regularly after the 3rd, 6th, 8th cycle and every additional 100 mg/m2 of doxorubicin. At the end of the study there were 212 evaluable patients. Prior to analysis, patients were stratified according to the presence of cardiac risks at study entry. One hundred thirty-three patients (63%) bore one or more cardiac risks. The average total cumulative dose of doxorubicin administered to the group was 311 mg/m2 (range: 200-900 mg/m2). Overall response (CR + PR) was 49.5% (105/212), with 12% of patients entering complete remission. General toxicity (WHO grading) was mild and tolerable; no excessive myelosuppression or related symptoms were observed. Three patients from the risk group experienced cardiotoxicity, with an LVEF fall below 45%, and had to be removed from the study. Another 3 patients (1 from the risk group) were removed from the study due to clinically documented congestive heart failure after 200, 300 and 400 mg/m2 of doxorubicin. In our study, Cardioxane (ICRF-187) did not influence the antitumor efficacy of FDC chemotherapy, nor did concomitant administration of Cardioxane and chemotherapy result in any other or severer toxicity than that already known for this regimen. Finally, the observation that 51% of patients with preexisting cardiac risks received doxorubicin at dose range of 450-900 mg/m2 without significant clinical or laboratory signs of cardiotoxicity supports the evidence that Cardioxane provided cardiac protection offering the possibility of longer doxorubicin chemotherapy.