gebhart/patrepeval huggingface dataset:
Whispering gallery mode resonance on an elliptical dielectric cylinder (1995)

Abstract With a view to application to millimeter wave integrated circuits, we analyze theoretically resonance characteristics of a whispering gallery mode (W.G. mode) propagating along a circumference of an elliptical dielectric cylinder. A wave equation is derived in an elliptic coordinate system and an eigenvalue equation includes Mathieu functions with a large order is obtained. Since this eigenvalue equation is an infinite dimensional determinant, we introduce a new technique to solve the eigenvalue equation. In this determinant, we pay our attention to diagonal elements that affect mainly resonance order. By means of this approach, it becomes possible to estimate a number of approximate terms of the eigenvalue equation to keep an accuracy of a resonance frequency constant even if an eccentricity of the ellipse is increased, namely the ellipse is flatter. It is also possible to find numerically the resonance frequency and electric field distribution of the W.G. mode for the elliptical cylinders with various eccentricity.
Measurement of Linear Dependence and Feedback Between Multiple Time Series (1982)

Abstract Measures of linear dependence and feedback for multiple time series are defined. The measure of linear dependence is the sum of the measure of linear feedback from the first series to the second, linear feedback from the second to the first, and instantaneous linear feedback. The measures are nonnegative, and zero only when feedback (causality) of the relevant type is absent. The measures of linear feedback from one series to another can be additively decomposed by frequency. A readily usable theory of inference for all of these measures and their decompositions is described; the computations involved are modest.
Regulation of small intestinal Na-P<sub>i</sub>type IIb cotransporter by dietary phosphate intake (1999)

Dietary restriction of phosphate is a well-known stimulator (acting indirectly via vitamin D(3)) of small intestinal apical Na-P(i) cotransport. In the present study, we document by Western blots and immunohistochemistry that, in mice, a low-P(i) diet given for several days leads (in parallel to a stimulation of Na-P(i) cotransport) to an increase of the abundance of the type IIb Na-P(i) cotransporter in the brush-border membrane of mouse enterocytes. Similar results were also obtained by an injection of cholecalciferol. The abundance of the type IIb transcript was investigated by Northern blots. These results indicated that the amount of the type IIb transcript was not changed by either low-P(i) diet or cholecalciferol. It is concluded that stimulation of intestinal Na-P(i) cotransport by low-P(i) diet and vitamin D(3) can be explained by an increased amount of type IIb Na-P(i) cotransporters in the brush-border membrane and that augmentation of type IIb Na-P(i) cotransporters is not related to an increased rate of transcription of the type IIb gene.
Endotracheal cuff undersizing diagnosed by computed tomography: Case report (2021)

We herein report a case in which the trachea could be completely sealed only when the cuff pressure reached 100 cmH<sub>2</sub>O. An excessive cross-sectional area of the trachea is a rare phenomenon, but we believe that our case will be helpful for clinicians who encounter similar situations.
Nutrients, age and cognitive function (1998)

Many nutrients or indices of nutritional status are associated with cognitive functioning, although the size of the effects on cognitive performance may be small. Results from recent studies, however, seem consistently to indicate that supplementation with beta-carotene and alpha-tocopherol, substances that promote antioxidant vitamins A and E, respectively, can be beneficial to cognitive function in elderly people. Folate rather than vitamin B12 appears to be associated with cognitive functioning. Furthermore the daily intake of ginkgo biloba extract can enhance cognitive performance and has been proved to delay cognitive decline in dementia. A proper dietary composition with regard to the ratio of carbohydrates to proteins, as well as the inclusion of sufficient micronutrients, seems to be favourable in the maintenance of cognitive function in the elderly. Glucose can enhance cognitive function, but a rapid decline of glucose levels may impair cognitive function or may induce feelings of lack of energy. Low doses of caffeine may also enhance cognitive function, although most studies on caffeine and cognition, as with studies on glucose and cognition, have not been carried out in elderly individuals. The effects of nutritional supplements are modest but do not seem to be very different from those of medicinal or investigational cognition-enhancing or anti-dementia drugs.
Numerical and Experimental Investigation of Flow Field in A 330MW Opposed Firing Boiler (2002)

In this paper, the flow field in opposed firing boiler is numerically simulated by means of k e two equations model. The simulation results indicate that the opposed firing way in this kind of boiler solves efficiently the problem of the temperature deviation at the furnace exit, which decreases greatly the possibility of tube rupture of the superheater and reheater in horizontal flueway due to exceedingly high temperature compared with that of the tangentially fired furnace. And the numerical results represent the experimental ones well. Figs 5, table 1 and refs 5.
Emodin inhibits migration and invasion of MHCC-97H human hepatocellular carcinoma cells (2016)

Emodin, an anthraquinone derivative from the root and rhizome of <i>Rheum palmatum</i> L., was found to have antitumor effects in different types of cancer by regulating multi-molecular targets. The aim of the present study was to explore the effect of emodin on the migration and invasion of MHCC-97H human hepatocellular carcinoma cells and the underlying molecular mechanisms. Firstly, it was demonstrated that emodin can inhibit cell proliferation and induce apoptosis of cells in a time- and dose-dependent manner, using a MTT assay and flow cytometry, respectively. However, when emodin concentration was <50 µmol/l, it had little effect on the inhibition of proliferation or the induction of apoptosis. Then, it was observed that emodin can significantly suppress cell migration and invasion with a treatment dose <50 µmol/l compared with the control (P<0.05), which was not attributed to a decrease in cell number. Further study demonstrated that emodin significantly suppressed the expression levels of matrix metalloproteinase (MMP)-2 and MMP-9 compared with the control, which may be mediated by the activation of the p38 mitogen-activated protein kinases (MAPK) signaling pathway and suppression of extracellular signal regulated kinase (ERK)/MAPK and phosphatidylinositol 3-kinase/Akt signaling pathways. Therefore, the present study, for the first time, used MHCC-97H cells, which have the high potential of malignant invasion, to demonstrate that emodin may inhibit cell migration and invasion.
Reactions of Vitamin E with Peroxides. II. Reaction of Benzoyl Peroxide with d-α-Tocopherol in Alcohols<sup>*</sup> (1965)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTReactions of Vitamin E with Peroxides. II. Reaction of Benzoyl Peroxide with d-α-Tocopherol in Alcohols*C. T. Goodhue and H. A. RisleyCite this: Biochemistry 1965, 4, 5, 854–858Publication Date (Print):May 1, 1965Publication History Published online1 May 2002Published inissue 1 May 1965https://pubs.acs.org/doi/10.1021/bi00881a009https://doi.org/10.1021/bi00881a009research-articleACS PublicationsRequest reuse permissionsArticle Views153Altmetric-Citations21LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Two-Color STED Imaging of Synapses in Living Brain Slices (2012)

STED microscopy is a novel fluorescence microscopy technique that breaks the classic diffraction barrier of optical microscopy. It offers the chance to investigate dynamic processes inside living cells with a spatial resolution well below 100 nm, possibly even down to a few nanometers, essentially without forgoing the benefits of conventional light microscopy, such as labeling specificity, sensitivity, and contrast. STED microscopy has already been exploited for several important neurobiological experiments. Given the tremendous potential as a transforming technology, it is important to understand how it works, and what its scope and limitations are. Here, we present a primer on STED microscopy, its basic principles and practical implementation, presenting a how-to guide on building and operating a STED microscope.
Sequences and a new code with spectral nulls at rational submultiples of the symbol frequency (1993)

Auxiliary pilot tone insertion, used for positioning the servo of magnetic or optical disk recorders, requires codes that give rise to a spectral null at an arbitrary frequency. Sequences with asymetrical runlength constraints containing spectral nulls at rational submultiples of the symbol frequency are investigated. A sufficient condition for spectral nulls at rational submultiples of the symbol frequency is given in terms of a simple runlength requirement. A new code with rate=1/3 is presented with spectral nulls at the normalized symbol frequencies 1/4, 1/2, and 3/4.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
The oncogene<i>EVI1</i>enhances transcriptional and biological responses of human myeloid cells to<i>all-trans</i>retinoic acid (2014)

The product of the ecotropic virus integration site 1 (EVI1) gene, whose overexpression is associated with a poor prognosis in myeloid leukemias and some epithelial tumors, regulates gene transcription both through direct DNA binding and through modulation of the activity of other sequence specific transcription factors. Previous results from our laboratory have shown that EVI1 influenced transcription regulation in response to the myeloid differentiation inducing agent, all-trans retinoic acid (ATRA), in a dual manner: it enhanced ATRA induced transcription of the RARβ gene, but repressed the ATRA induction of the EVI1 gene itself. In the present study, we asked whether EVI1 would modulate the ATRA regulation of a larger number of genes, as well as biological responses to this agent, in human myeloid cells. U937 and HL-60 cells ectopically expressing EVI1 through retroviral transduction were subjected to microarray based gene expression analysis, and to assays measuring cellular proliferation, differentiation, and apoptosis. These experiments showed that EVI1 modulated the ATRA response of several dozens of genes, and in fact reinforced it in the vast majority of cases. A particularly strong synergy between EVI1 and ATRA was observed for GDF15, which codes for a member of the TGF-β superfamily of cytokines. In line with the gene expression results, EVI1 enhanced cell cycle arrest, differentiation, and apoptosis in response to ATRA, and knockdown of GDF15 counteracted some of these effects. The potential clinical implications of these findings are discussed.
Chronic obstructive pulmonary disease exacerbations: latest evidence and clinical implications (2014)

Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortality worldwide and results in an economic and social burden that is both substantial and increasing. The natural history of COPD is punctuated by exacerbations which have major short- and long-term implications on the patient and healthcare system. Evidence-based guidelines stipulate that early detection and prompt treatment of exacerbations are essential to ensure optimal outcomes and to reduce the burden of COPD. Several factors can identify populations at risk of exacerbations. Implementing prevention measures in patients at risk is a major goal in the management of COPD.
Self-Assembled Carbohydrate-Stabilized Ceramic Nanoparticles for the Parenteral Delivery of Insulin (2000)

The insulin-bearing aquasomes were fabricated by first preparing the nanosize calcium phosphate dihydrate core. The calcium phosphate dihydrate core was prepared by colloidal precipitation and sonication of disodium hydrogen phosphate solution and calcium chloride solution at low temperature. This core was coated with cellobiose, pyridoxal-5-phosphate, or trehalose under sonication and was further loaded with the drug at low temperature by a partial adsorption mechanism. The prepared systems were characterized for size, shape, size distribution, drug loading efficiency, and in vivo performance. The in vivo performance of the formulated aquasome was compared with standard porcine insulin solution, and better results were observed compared to insulin solution.
Localized EM and photonic jets from non‐spherical and non‐symmetrical dielectric mesoscale objects: Brief review (2015)

The interest to mesoscale dielectric objects, whose effective dimensions are comparable with the incident radiation wavelength, is caused by their unique ability to modify the spatial structure of the incident wave in the specific manner and to produce a highly localized intensive optical flux (“photonic jet”) with the subwavelength spatial resolution. In the current paper we brief review the modern state‐of‐the‐art of main principles of the photonic jet formation by non‐spherical and non‐symmetrical dielectric mesoscale particles both in transmitting and reflection mode. A deeper understanding of the photonic jet is nevertheless needed to fully exploit the potential performance of nano‐ and micro‐ dielectric mesoscale objects as diffractive components at different wavebands. image
Impact of Elevated Atmospheric Carbon Dioxide and Water Deficit on Flower Development and Pyrethrin Accumulation in Pyrethrum (2015)

Crop responses in a changing climate reflect the interplay among rising temperature, changing rainfall patterns and increasing atmospheric Carbon dioxide (CO2) concentrations. Exposure of plants to elevated atmospheric CO2 not only induces the changes in primary metabolism, but also leads to complex alterations in secondary metabolism. Elevated CO2 could delay the onset of water deficit and counterbalance negative effects of water deficit on plant growth by increasing water use efficiency. Pyrethrum (Tanacetum cinerariifolium) is commercially grown for extraction of pyrethrin in the achenes of the flower heads. Pyrethrin is classified as terpenoid and widely used as a natural insecticide. The response of pyrethrum, a perennial crop producing important secondary metabolites, to climate change is not known. In this experiment, plants were subjected to two water treatments (well-watered and water deficit) at two atmospheric CO2 concentrations (ambient CO2: 390 ppm and elevated CO2: 700 ppm). Watering treatments were applied throughout the flowering period, until physiological maturity of flowers. Selected growth, yield, phenological and physiological traits were measured to understand the effects of elevated atmospheric CO2 and water deficit on flower development and pyrethrin accumulation. The results of this experiment showed that exposure to elevated atmospheric CO2 throughout the flowering period, significantly increased flower yield and pyrethrin yield per plant (Figure. 1) at physiological maturity due to the production of more flowers. Elevated CO2 treatments significantly increased the rate of flower development resulting in shorter flowering period and lower pyrethrin yield per flower compared to ambient CO2 treatments. Exposure to water deficit during the post-anthesis period significantly reduced flower yield and total pyrethrin yield compared to well-watered treatments. The interaction of water deficit with elevated atmospheric CO2 increased the rate of flower development resulting in shorter flowering period and lower pyrethrin yield. Adequate soil moisture for flower development increased the rate and duration of pyrethrin accumulation resulting in higher pyrethrin yield per flower.
[Risk factors and prevention of postmenopausal osteoporosis]. (1995)

Preventing postmenopausal bone loss and osteoporotic fractures (vertebral crush fractures and femoral neck fractures) is an important challenge for the next decades. This goal should be achieved by developing screening strategies and deploying established preventive measures. The risk assessment is currently based on densitometric measurements of bone mass and knowledge of risk factors for low bone mass and/or exaggerated bone loss. Hormone replacement therapy is the only well established treatment for preventing osteoporotic fractures. Therefore, it should be recommended to many women. It is important to associate a progesterone derivative with the oestrogen, to exclude patients with breast cancer history and to ensure a follow up by a gynaecologist. Alternative regimens could be useful in patients with low acceptance or contraindication to oestrogens. The long term antifracture efficacy of these molecules remains to be determined, and they have yet, at least in France, no marketing authorization for this purpose.
Synchrotron radiation circular dichroism spectroscopy of proteins and applications in structural and functional genomics (2005)

The technique of Synchrotron Radiation Circular Dichroism (SRCD) spectroscopy and its advantages over conventional circular dichroism spectroscopy are described in this tutorial review, as well as recent applications of the technique in structural and functional genomics. Circular dichroism (CD) spectroscopy is a well-established method in biological chemistry and structural biology, but its utility can be limited by the low flux of the light source in the far ultraviolet and vacuum ultraviolet wavelength regions in conventional CD instruments. The development of synchrotron radiation circular dichroism (SRCD), using the intense light of a synchrotron beam, has greatly expanded the utility of the method, especially as a tool for both structural and functional genomics. These applications take advantage of the enhanced features of SRCD relative to conventional CD: the ability to measure lower wavelength data containing more electronic transitions and hence more structural information, the higher signal-to-noise hence requiring smaller samples, the higher intensity enabling measurements in absorbing buffers and in the presence of lipids and detergents, and the ability to do faster measurements enabling high throughput and time-resolved spectroscopy.This article discusses recent developments in SRCD instrumentation, software, sample preparation and methods of analyses, with particular emphasis on their applications to the study of proteins. These advances have led to new applications in structural genomics (SG), including the potential for fold recognition as a means of target selection and the examination of membrane proteins, a class of proteins usually excluded from SG programmes. Other SG uses include detection of macromolecular interactions as a screen for complex formation, and examination of glycoproteins and sugar components. In functional genomics (FG) new applications include screening for ligand binding as a means of identifying function, and examination of structural differences in mutant proteins as a means of gaining insight into function.
BlueID: Enabling robust in-car localization and on-demand personalization using Bluetooth (2017)

Connected car has become one of the fastest growing segments in the IoT market. A key feature of connected car solutions is personalization. An advanced solution shall be able to enable complete personalization for each seat automatically. This paper presents the design and implementation of BlueID - a framework for robust in-car localization and on-demand personalization using Bluetooth Low Energy (BLE) beacons. BlueID identifies a user based on the user's mobile device and characterizes each seat using signals received from a pre-installed BLE beacon array. BlueID features a machine learning engine that can robustly distinguish seats in the presence of various environment and system dynamics such as varied antenna sensitivities and multiple seat occupants. To enable on-demand use cases, BlueID employs a connected car cloud platform to store each vehicle's seat prediction model and each user's personalization profile. The prediction model and the user's personalization profile are retrieved to personalize the environment where the user sits when the user enters the vehicle. We have implemented a prototype of BlueID and evaluated it through extensive experiments. The results show that BlueID achieves satisfactory in-car localization performance with average position accuracy over 98%.
The complexity of DNA (1997)

This article includes Supplementary Material available from the authors upon request or via the Internet at http://www.interscience.wiley.com/jpages/1076-2787/suppmat/3/v3.33.html Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
Terrain following and terrain avoidance algorithms (1989)

The purpose of terrain following (TF) for military aircraft is to use the protection from enemy sight afforded by terrain masking. A usual requirement is to remain as close as possible above a given distance, the 'set clearance height', from the ground. Conventionally a forward looking terrain following radar (TFR) is used to provide range and angle information of points on the ground for processing into a TF pitch plane command. A problem with using a TRF for implementing TF is that it is far from covert. The author considers the application of terrain referenced navigation systems (TRN) for guidance. These techniques improve the accuracy of the aircraft primary dead reckoning system, typically an inertial navigation system, by using additional information obtained from radar altimeter returns and a stored digital terrain map.