gebhart/patrepeval huggingface dataset:
Combined interferon-alpha 2, rimantadine hydrochloride, and ribavirin inhibition of influenza virus replication in vitro (1984)

Recombinant DNA-produced human interferon-alpha 2 inhibited the replication of influenza A and B viruses in primary rhesus monkey kidney cells (RMK). Human interferon-alpha 2 interacted additively or synergistically with rimantadine hydrochloride or ribavirin in reducing the yield of clinical isolates of either H3N2 or H1N1 subtype influenza A viruses. The combination of human interferon-alpha 2 and ribavirin also inhibited the replication of an influenza B virus to a greater extent than either single agent. In addition to drug concentration, the virus inoculum and duration of culture were important variables in determining the degree of inhibition. Single drugs or combinations did not significantly inhibit the growth of uninfected RMK cells, which indicated that the observed interactions with respect to antiviral activity were not due to cell cytotoxicity.
Mydriatic Effectiveness of Dilute Combinations of Phenylephrine and Tropicamide (1982)

The effects of two solutions, each consisting of a combination of tropicamide and phenylephrine at lower than conventional concentrations, were studied in 79 students at Pacific University College of Optometry. Clinically effective diameters (CED's), measured when the eye was illuminated for direct ophthalmoscopy, were followed for 90 min after mydriatic instillation. Intraocular pressure (IOP), systolic arterial blood pressure (sBP), and the systolic BP/IOP ratio were also monitored for 90 min. Both combination A (0.25% tropicamide + 1.25% phenylephrine) and combination B (0.125% tropicamide + 2.0% phenylephrine) produced CED's as large as produced by 0.5% tropicamide in the opposite eye. By combining a low concentration of a sympathomimetic with a parasympatholytic agent, it is possible to achieve mydriasis superior to that produced by 0.5% tropicamide or 2.5% phenylephrine while reducing the risk of systemic or ocular side effects.
Targeting soluble guanylate cyclase for the treatment of pulmonary hypertension (2011)

Pulmonary arterial hypertension is a disease characterized by a sustained increase in pulmonary arterial pressure leading to right heart failure. Current treatments focus on endothelial dysfunction and an aberrant regulatory pathway for vascular tone. Unfortunately, a large proportion of patients are unresponsive to conventional vasodilator therapy. Investigations are ongoing into the effects of experimental therapies targeting the signal transduction pathway that mediates vasodilation. Here, we briefly discuss the pathophysiology of pulmonary hypertension and endothelial dysfunction, along with current treatments. We then present a focused review of recent animal studies and human trials examining the use of activators and stimulators of soluble guanylate cyclase for the treatment of pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension.
BIOLOGICALLY BASED TOP-DOWN ATTENTION MODULATION FOR HUMANOID INTERACTIONS (2008)

An adaptive perception system enables humanoid robots to interact with humans and their surroundings in a meaningful context-dependent manner. An important foundation for visual perception is the selectivity of early vision processes that enables the system to filter out low-level unimportant information while attending to features indicated as important by higher-level processes by way of top-down modulation. We present a novel way to integrate top-down and bottom-up processing for achieving such attention-based filtering. We specifically consider the case where the top-down target is not the most salient in any of the used submodalities.
Human embryonic stem cell-derived mesenchymal stromal cells ameliorate collagen-induced arthritis by inducing host-derived indoleamine 2,3 dioxygenase (2016)

Treatment with hESC-MSC ameliorates CIA by inducing IFNγ(+) Th1 cells and IDO1 in the host. Thus, hESC-MSC can provide an infinite cellular source for treatment of rheumatoid arthritis.
A unified analysis of both active and passive damping for a plate with piezoelectric transducers (1993)

The complete set of equations for describing the mechanical and electrical behavior of a piezoelectric medium is given. From these equations, the electromechanical equations describing the dynamical behavior of discrete PZTs and their mounting plate are derived. The electromechanical equations are used to explain active damping with the PZTs as actuators and an accelerometer as the sensor. The active damping model is applied to a more realistic case. The transverse displacement and the plate vibration damping are calculated using the electromechanical equations and compared with the experimental results. A comparison of the open loop transverse displacement of the plate as a function of the applied PZT voltage with the corresponding experimental case shows good agreement. The damping of the plate vibration is found to be approximately 20 dB for both the calculation and the corresponding experiment when the plate is driven at the lowest modal plate frequency. A sensor equation describing the output of a PZT used as a sensor is derived with the PZT terminated with an arbitrary impedance. Using the sensor equation, a concise and unified approach is developed for constructing both active and passive damping methods. Two limiting active damping cases (the terminal impedance zero or infinity) and one passive damping case are considered using the sensor equation. A useful design guide for the corresponding active and passive damping methods is determined.
Knowledge driven discovery for opportunistic IoT networking (2015)

So far, the Internet of Things (IoT) has been concerned with the objective of connecting every-thing, or any object to the Internet world. By collaborating towards the creation of new services, the IoT has introduced the opportunity to add smartness to our cities, homes, buildings and healthcare systems, as well as businesses and products. In many scenarios, objects or IoT devices are not always statically deployed, but they may be free to move around being carried by people or vehicles, while still interacting with static IoT infrastructure. The Opportunistic Networking paradigm states that, exploiting opportunistic interactions between static and mobile IoT devices, provides for increased network capacity, additional connectivity, reduced deployment costs, improved reliability and overall network lifetime improvements. IoT scenarios do illustrate the increased need to identify and exploit opportunistic interactions between IoT devices in order to recognize when an opportunity for communication is possible. For example, statically deployed devices (i.e. road side sensors) may need to find mobile devices (this may be sensors or actuators) (i.e. connected cars) for exploiting them for collecting and relaying data towards destinations without relying on a static infrastructure. This means that discovery in IoT scenarios needs to determine the availability of other devices in scenarios in which devices' presence is uncertain or may change over time. This directly leads to a contradicting objective where resource wastage in device discovery is to be kept at a minimum. This thesis presents two contributions that provide solutions to overcome the clash between these contradicting objectives. Firstly, a Context Aware Resource Discovery mechanism is introduced, capable of providing optimized discovery and adapting available resources based on learned mobility patterns. Secondly, an Arrival and Departure Time Prediction and Discovery framework is defined and investigated; this framework aims to predict future arrival and departure times and helps to plan the use of devices' resources in advance based on the foreseen resource demand patterns.
[Cholesterol ester storage disease and sea-blue histiocytes]. (1987)

A case of cholesteryl ester storage disease (CESD) was found by liver biopsy in a 5-year-old boy. Hepatosplenomegaly, varying elevations of serum transaminases and hyperlipoproteinemia, type IIb, were detected clinically. The liver tissue was yellow. The cytoplasm of hepatocytes and Kupffer cells was foamy. In frozen sections these cells stained with dyes and histochemical methods for neutral lipids, unsaturated lipids, and cholesterol, but not with dyes for phospholipids and glycosaminoglycans. Under polarized light a large quantity of birefringent storage material was visible. We determined the lipid composition histochromatographically and found a very substantial increase in cholesteryl ester content and a moderate increase in triglycerides compared to control liver tissue. These findings are in agreement with our former case of CESD (1979). But in contrast to the liver tissue of the first patient there was more pronounced hepatic periportal and intralobular fibrosis in the second case. Remarkable amounts of ceroid storing histiocytes, so called "sea-blue histiocytes" were visible within the fibrous tissue. The granules of these cells stained with dyes for neutral lipids, phospholipids, glycosaminoglycans, and sea-blue with Giemsa in both frozen sections and paraffin-embedded liver tissue. They showed a yellow autofluorescence and were partly birefringent. Ceroid is believed to be the product of lipid peroxidation, binding to protein and polymerization. Therefore we suggest an additional deficiency of tissue antioxidants at the storage sites in such cases of CESD and this may potentiate liver fibrosis.
THE CRISTOBALITE LIQUIDUS IN THE ALKALI OXIDE-SILICA SYSTEMS AND THE HEAT OF FUSION OF CRISTOBALITE (1930)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTTHE CRISTOBALITE LIQUIDUS IN THE ALKALI OXIDE-SILICA SYSTEMS AND THE HEAT OF FUSION OF CRISTOBALITEF. C. KracekCite this: J. Am. Chem. Soc. 1930, 52, 4, 1436–1442Publication Date (Print):April 1, 1930Publication History Published online1 May 2002Published inissue 1 April 1930https://pubs.acs.org/doi/10.1021/ja01367a021https://doi.org/10.1021/ja01367a021research-articleACS PublicationsRequest reuse permissionsArticle Views290Altmetric-Citations70LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
O (n) Scheduling Algorithms for Real-Time Multiprocessor Systems. (1989)

The herbicide bromoxynil (3,5-dibromo-4-hydroxybenzonitrile) is a photosynthetic (photosystem II) inhibitor in plants. A gene, bxn, encoding a specific nitrilase that converts bromoxynil to its primary metabolite 3,5-dibromo-4-hydroxybenzoic acid, was cloned from the natural soil bacterium Klebsiella ozaenae. For expression in plants, the bxn gene was placed under control of a light-regulated tissue-specific promoter, the ribulose bisphosphate carboxylase small subunit. Transfer of this chimeric gene and expression of a bromoxynil-specific nitrilase in leaves of transgenic tobacco plants conferred resistance to high levels of a commercial formulation of bromoxynil. The results presented indicate a successful approach to obtain herbicide resistance by introducing a novel catabolic detoxification gene in plants.
Extracting the author of web pages (2008)

In this paper, we define the problem of identifying the author of a Web page as a sub-problem of identifying the information sender configuration of a Web page. We propose a method that extracts the author name candidates from a Web page based on linguistic features, and rank the candidates based on local features such as distance from the main content. The evaluation shows that we can achieve more than 75% precision when evaluated with candidates ranked within top five.
On Monte Carlo Tree Search and Reinforcement Learning (2017)

Fuelled by successes in Computer Go, Monte Carlo tree search (MCTS) has achieved widespread adoption within the games community. Its links to traditional reinforcement learning (RL) methods have been outlined in the past; however, the use of RL techniques within tree search has not been thoroughly studied yet. In this paper we re-examine in depth this close relation between the two fields; our goal is to improve the cross-awareness between the two communities. We show that a straightforward adaptation of RL semantics within tree search can lead to a wealth of new algorithms, for which the traditional MCTS is only one of the variants. We confirm that planning methods inspired by RL in conjunction with online search demonstrate encouraging results on several classic board games and in arcade video game competitions, where our algorithm recently ranked first. Our study promotes a unified view of learning, planning, and search.
MIMO antenna with Wi-Fi and Blue-Tooth for smart watch applications (2015)

This paper presents an Inverted-F Antennas (IFAs) type MIMO antenna with Wi-Fi and Blue-Tooth band for smart watch application. The overall dimensions of 40×40×5.4 mm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sup> of the proposed design consisting of an antenna portion of 40×5×0.1 mm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sup> and system ground portion of 40×40×0.4 mm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sup> . The antenna geometry is composed of two identical IFA antennas extended from the two side of the ground, which designed on the FR4 substrate. The distance between both antennas is 40 mm. The measured results show that S11 is lower than -10 dB and the isolation S12 is better than -15 dB across the bands of Wi-Fi and Blue-Tooth. As these antennas are dedicated to be placed in watch, the influence of ABS and screen on the smart watch for the antenna performances is also investigated. The proposed antenna design also has good performance and small size.
GSLIB: Geostatistical Software Library and User's Guide (1993)

Thirty-seven programs that summarize data with histograms and other graphics, calculate measures of spatial continuity, provide smooth least-squares-type maps, and perform stochastic spatial simulation.
Reliability analysis of the auto-tracked FSO communication links (2010)

The effects of auto-tracking subsystems on the bit-error-rate (BER) and reliability of free-space optical (FSO) communication links are investigated. Based on Gaussian beam formula on the receiver plane and considering the atmosphere losses due to absorption, scattering and atmospheric turbulence numerical values for Power In Bucket (PIB), Signal to Noise Ratio (SNR) and BER are calculated. Using above mentioned values, the role of auto-track subsystems on link reliability improvement is described. The results are illustrated by graphs obtained by calculation and simulation.
Monitoring and Control of Optical Thin Film "Fencepost" Designs of Various Types (2007)

The monitoring of Fencepost Designs offers error compensation and reduction. There tend to be two or more extrema within the monitoring of each layer between the fenceposts. This has a self calibrating effect on layers.
Acid-catalyzed rearrangements of cyclopropyl ketones related to eudesmane (1980)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAcid-catalyzed rearrangements of cyclopropyl ketones related to eudesmaneDrury Caine, Samuel Lindsay Graham, and Tushar T. VoraCite this: J. Org. Chem. 1980, 45, 19, 3798–3802Publication Date (Print):September 1, 1980Publication History Published online1 May 2002Published inissue 1 September 1980https://pubs.acs.org/doi/10.1021/jo01307a014https://doi.org/10.1021/jo01307a014research-articleACS PublicationsRequest reuse permissionsArticle Views172Altmetric-Citations6LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Fabrication and flexural strength of ultrafine-grained yttria-stabilized zirconia (1976)

Ultrafine powders of yttria-stabilized zirconia were fabricated into specimens by die pressing, extrusion and slip casting. Gross pores present in unfired specimens varied with fabrication procedure and persisted in the fired microstructures. Pressure-cast specimens with no apparent internal pores larger than grain size and with as-fabricated surfaces containing surface pores approximately 2 ..mu..m exhibited mean flexural strengths as high as 129 kpsi. The ultimate flexural strength of extruded and pressed specimens appeared to be limited by residual coarse pores near the surface, and flexural strengths ranged as low as 16 kpsi.
Upright and Stabilized Omnidirectional Depth Estimation for Wide-baseline Multi-camera Inertial Systems (2020)

This paper presents an upright and stabilized omnidirectional depth estimation for an arbitrarily rotated wide- baseline multi-camera inertial system. By aligning the reference rig coordinate system with the gravity direction acquired from an inertial measurement unit, we sample depth hypotheses for omnidirectional stereo matching by sweeping global spheres whose equators are parallel to the ground plane. Then, unary features extracted from each input image by 2D convolutional neural networks (CNN) are warped onto the swept spheres, and the final omnidirectional depth map is output through cost computation by a 3D CNN-based hourglass module and a softargmax operation. This can eliminate wavy or unrecognizable visual artifacts in equirectangular depth maps which can cause failures in scene understanding. We show the capability of our upright and stabilized omnidirectional depth estimation through experiments on real data.
MicroRNA-101 attenuates pulmonary fibrosis by inhibiting fibroblast proliferation and activation (2017)

Aberrant proliferation and activation of lung fibroblasts contribute to the initiation and progression of idiopathic pulmonary fibrosis (IPF). However, the mechanisms responsible for the proliferation and activation of fibroblasts are not fully understood. The objective of this study was to investigate the role of miR-101 in the proliferation and activation of lung fibroblasts. miR-101 expression was determined in lung tissues from patients with IPF and mice with bleomycin-induced pulmonary fibrosis. The regulation of miR-101 and cellular signaling was investigated in pulmonary fibroblasts <i>in vitro</i> The role of miR-101 in pulmonary fibrosis <i>in vivo</i> was studied using adenovirus-mediated gene transfer in mice. The expression of miR-101 was down-regulated in fibrotic lungs from patients with IPF and bleomycin-treated mice. The down-regulation of miR-101 occurred via the E26 transformation-specific (ETS) transcription factor. miR-101 suppressed the WNT5a-induced proliferation of lung fibroblasts by inhibiting NFATc2 signaling via targeting Frizzled receptor 4/6 and the TGF-β-induced activation of lung fibroblasts by inhibition of SMAD2/3 signaling via targeting the TGF-β receptor 1. Adenovirus-mediated miR-101 gene transfer in the mouse lung attenuated bleomycin-induced lung fibrosis and improved lung function. Our data suggest that miR-101 is an anti-fibrotic microRNA and a potential therapeutic target for pulmonary fibrosis.
Performance of a versatile variable‐volume permeability cell. Comparison of gas permeability measurements by the variable‐volume and variable‐pressure methods (1963)

Abstract An improved cell which permits the measurement of permeabilities of membranes to gases over a wide range of temperatures and gas pressures is described. The measurements are made by the variable volume method, under constant pressure differential across the membrane. The cell lends itself particularly well to routine tests, because it does not require calibration or the use of vacuum techniques. The performance of the cell is discussed, and typical experimental results are presented. A modified permeability cell of the same type for high‐pressure studies is also described. Measurements with this apparatus show that the rate of gas permeation obeys, in some cases, a single from of Fick's law, even under pressure differentials across the membrane as high as 800 psi (54 atm.). The paper also compares permeability data obtained by the variable volume and the variable pressure methods. The permeability of 0.002 in.‐thick Alathon 15 polyethylene to oxygen and nitrogen was determined between 0 and 50°C. by the two methods, using the same sample of membrane in situ , and the measurements were found to agree within experimental error. Permeabilites of 0.010 in.‐thick samples of Alathon 15 polyethylene to nitrogen, oxygen, helium, and carbon dioxide obtained in the same temperature range by the variable volume method were 15–30% higher than the corresponding data determined by the variable pressure method. This discrepancy could be due to the fact that the variable pressure measurements with the thicker membrances may not have been made under true steady‐state conditions, although permeabilities were determined from apparently linear sections of permeated gas pressure vs . time curves. A critical re‐examination of the methods used to determine permeability constants is suggested.