gebhart/patrepeval huggingface dataset:
Modélisation et évaluation des performances de disponibilité d'un avion dans un contexte opérationnel lors des phases de conception (2008)

Ce rapport de thèse traite de la modélisation et de l'évaluation de la disponibilité d'un avion en phase de conception. Ce problème est crucial pour les concepteurs aéronautiques car il leur permet d'évaluer des indicateurs de disponibilité afin d'améliorer la conception des systèmes et d'optimiser le soutien de l'avion. Nous avons formalisé le processus dynamique des incidents techniques et leurs effets sur la maintenance corrective lors de l'exploitation de l'avion par une compagnie aérienne. Dans le contexte d'une mission, définie par une séquence de cycles de vol, les méthodes classiques de fiabilité des systèmes ne sont pas utilisables en respectant les contraintes industrielles de temps de calcul. Basée sur des développements analytiques, nous introduisons une méthodologie qui fournit un algorithme efficace de calcul des bornes des indicateurs de disponibilité. Finalement, nous montrons l'utilité de notre approche par des expérimentations inspirées de cas réels de systèmes d'un avion.
TEM Measurements in Bolivia - Comparison of Different Fast Interpretation Methods (1998)

A geophysical survey using Audiomagnetotellurics (AMT), Transient-Electromagnetics (TEM) and Induced-Polarisation (IP) measurements was carried out near the former silver mine at Pulacayo, Bolivia, in 1995. The aim of the survey was to support a structural geology investigation of the mineralized volcanic stock. TEM soundings seem to present the most useful information.
Synthesis of hexamethylglutaric acid: an approach to compounds with adjacent quaternary carbon centers (1988)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSynthesis of hexamethylglutaric acid: an approach to compounds with adjacent quaternary carbon centersJanusz Baran and Herbert MayrCite this: J. Org. Chem. 1988, 53, 19, 4626–4628Publication Date (Print):September 1, 1988Publication History Published online1 May 2002Published inissue 1 September 1988https://pubs.acs.org/doi/10.1021/jo00254a052https://doi.org/10.1021/jo00254a052research-articleACS PublicationsRequest reuse permissionsArticle Views286Altmetric-Citations12LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
SPECTROSCOPIC ADMITTIVITY IMAGING OF BIOLOGICAL TISSUES: CHALLENGES AND FUTURE DIRECTIONS (2014)

Medical imaging techniques have evolved to expand our ability to visualize new contrast information of electrical, optical, and mechanical properties of tissues in the human body using noninvasive measurement methods. In particular, electrical tissue property imaging techniques have received considerable attention for the last few decades since electrical properties of biological tissues and organs change with their physiological functions and pathological states. We can express the electrical tissue properties as the frequency-dependent admittivity, which can be measured in a macroscopic scale by assessing the relation between the time-harmonic electric field and current density. The main issue is to reconstruct spectroscopic admittivity images from 10 Hz to 1 MHz, for example, with reasonably high spatial and temporal resolutions. It requires a solution of a nonlinear inverse problem involving Maxwell's equations. To solve the inverse problem with practical significance, we need deep knowledge on its mathematical formulation of underlying physical phenomena, implementation of image reconstruction algorithms, and practical limitations associated with the measurement sensitivity, specificity, noise, and data acquisition time. This paper discusses a number of issues in electrical tissue property imaging modalities and their future directions.
Mechanistic investigations into interactions between IGF-I and IGFBPs and their impact on facilitating cell migration on vitronectin (2010)

Numerous studies have reported links between insulin-like growth factors (IGFs) and the extra-cellular matrix protein vitronectin (VN). We ourselves have reported that IGF-I binds to VN via IGF-binding proteins (IGFBPs) to stimulate HaCaT and MCF-7 cell migration. Here, we detail the functional evaluation of IGFBP-1, -2, -3, -4 and -6 in the presence and absence of IGF-I and VN. The data presented here, combined with our prior data on IGFBP-5, suggest that IGFBP-3, -4 and -5 are the most effective at stimulating cell migration in combination with IGF-I and VN. In addition, we demonstrate that different regions within IGFBP-3 and -4 are critical for complex formation. Furthermore, we examine whether multi-protein complexes of IGF-I and IGFBPs associated with fibronectin and collagen IV are also able to enhance functional biological responses.
Effects of Temperature on Membrane in Sheep Heart Pubkinje Fibers Currents (1972)

Influences of temperature (32℃-38℃） on membrane currents of sheep heart purkinje fiber were examined by means of voltage clamp technique which was done by double microelectrode impalement into a a short strip of the fiber. A slowly decreasing inward current following to an initial rapid inward current was observed in Na-Tyrode solution when the membrane potential was held between-20mV and -40mV. In Na-free solution (Choline-Tyrode), only outward current which gradually decays with the progress of time was observed in depolarizing clamp. The time course of slow inward current is shrtiened in high temperature, but not much prolonged in low temperature. The time course of outward current is prolonged in low temperature but a little shortened in high temperature is mainly caused by the early disappearance of slow inward current carried by Na+ and the prolongation is mainly coused by the slow decay of the outward current carried by K+.
Kinetics of trace metal complexation: role of alkaline-earth metals (1988)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTKinetics of trace metal complexation: role of alkaline-earth metalsJanet G. Hering and Francois M. M. MorelCite this: Environ. Sci. Technol. 1988, 22, 12, 1469–1478Publication Date (Print):December 1, 1988Publication History Published online1 May 2002Published inissue 1 December 1988https://pubs.acs.org/doi/10.1021/es00177a014https://doi.org/10.1021/es00177a014research-articleACS PublicationsRequest reuse permissionsArticle Views572Altmetric-Citations121LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Nickel sulfide, iron-nickel sulfide and iron sulfide precipitation by a newly isolated Desulfotomaculum species and its relation to nickel resistance (1994)

A Desulfotomaculum sp. (DF-1) isolated from a sulfate reduction bioremediation pilot plant in Chengdu (P.R.C.) was resistant to 360 (6.1 mM), 450 (7.7 mM), and 550 ppm (9.4 mM) Ni(II) in the presence of 0, 100 (1.8 mM), and 200 ppm (3.6 mM) Fe(II), respectively. When cultured in the presence of Ni (II) with or without Fe, DF-1 produced a dark-brown, soluble product. Only small amounts of Ni and or Fe were precipitated at the cell surface when cells were subjected to 100 ppm concentrations of the metals. However, in the presence of Fe(II) only, large amounts of FeS (70% of the Fe) were precipitated at the bacterial cell surface and extracellularly. The increase of Ni in the growth medium was inversely related to the concentration of Fe precipitated as a sulfide. This coincided with the formation of dark-brown, soluble Ni-proteins, consisting of a range of polypeptides from approx. 70–120 kDa, which inhibited NiS formation and promoted Fe-complexation. These autolysis-inducible proteins and cell wall autolysis by-products bound Ni, and are thought to confer Ni-resistance in DF-1. Harsh treatments, such as acidification of culture supernatants from Ni-grown DF-1, destabilized the Ni-organic complexes, and resulted in the precipitation of an amorphous Ni-rich material.
Seroprevalence of antibodies to HTLV-I In patients with chronic neurological disorders other than tropical spastic paraparesis (1988)

Human T-lymphotropic virus type I (HTLV-I), the etiological agent of adult T-cell leukemia/lymphoma, also appears to be the cause of tropical spastic paraparesis, a chronic myelopathy reported in several different regions of the world. The prevalence of antibodies to HTLV-I in patients with chronic neurodegenerative disorders other than tropical spastic paraparesis and in patients with some muscle inflammatory disorders has been investigated. IgG antibodies to HTLV-I were measured in the sera and/or cerebrospinal fluid from 82 Guamanian patients with amyotrophic lateral sclerosis and parkinsonism-dementia, 164 Guamanian normal controls, 10 patients with kuru from the Eastern Highlands of Papua New Guinea, 4 patients with Viliuisk encephalomyelitis from the Iakut region of eastern Siberia, 45 Italian patients with multiple sclerosis, and 56 patients with polymyositis (49 from the United States and 7 from Jamaica). As determined by enzyme-linked immunosorbent assay, Western immunoblot, and gelatin particle agglutination techniques, serological evidence of HTLV-I infection was found in 1 patient with amyotrophic lateral sclerosis and 1 control subject from Guam, and in 1 patient from the United States and all 7 Jamaican patients with polymyositis. Except for the high seropositivity rate among the group of Jamaican patients with polymyositis, our data indicate that HTLV-I is an unlikely causative agent in the spectrum of the neurological diseases examined. The seropositivity of the 7 Jamaican patients with polymyositis requires further study.
Imidazole catalyses in aqueous systems. VI. Enzyme-like catalysis in the hydrolysis of a phenyl ester by phenylimidazole-containing copolymers. Correlation between binding capacity and catalytic activity (1971)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTImidazole catalyses in aqueous systems. VI. Enzyme-like catalysis in the hydrolysis of a phenyl ester by phenylimidazole-containing copolymers. Correlation between binding capacity and catalytic activityToyoki Kunitake and Seiji ShinkaiCite this: J. Am. Chem. Soc. 1971, 93, 17, 4256–4263Publication Date (Print):August 1, 1971Publication History Published online1 May 2002Published inissue 1 August 1971https://pubs.acs.org/doi/10.1021/ja00746a028https://doi.org/10.1021/ja00746a028research-articleACS PublicationsRequest reuse permissionsArticle Views165Altmetric-Citations30LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
<title>Integration of LIGA structures with CMOS circuitary</title> (1997)

Successful direct integration of a mechanical structure fabricated by LIGA on a Si chip containing CMOS circuitry has been achieved in this work. A 1D cantilever accelerometer is chosen as a vehicle to demonstrate this integration process. The capacitive sensor element employs one electrode formed in the Si substrate during the integrated circuit fabrication. The other electrode is fabricated using the LIGA technique with sacrificial layer etching. Details of the fabrication process to achieve this integration are given. Need for careful control of stress in the deposited layers and achieving appropriate contrast in the X-ray mask are delineated.
Inelastic Light Scattering from Magnetic Fluctuations in<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mrow><mml:msub><mml:mrow><mml:mi>CuGeO</mml:mi></mml:mrow><mml:mrow><mml:mn>3</mml:mn></mml:mrow></mml:msub></mml:mrow></mml:math> (1996)

Magnetic fluctuations in ${\mathrm{CuGeO}}_{3}$ are studied using inelastic light scattering experiments over a broad temperature range. In the dimerized phase $(T<14\phantom{\rule{0ex}{0ex}}\mathrm{K})$, scattering resulting from maxima in the magnonlike density of states and from spin-phonon coupled modes are reported. In the short-range order regime of the uniform phase $(14<T<60\phantom{\rule{0ex}{0ex}}\mathrm{K})$ the results confirm the existence of a spin-wave continuum, as expected for a one-dimensional quantum Heisenberg chain. At high temperatures $(T>60\phantom{\rule{0ex}{0ex}}\mathrm{K})$ clear evidence is given for the existence of low-dimensional diffusive fluctuations.
A runtime approach for software fault analysis based on interpolation (2010)

In the application system, obtaining the information of the system at runtime and analyzing them are important for system adjustment. Many runtime metrics can be collected from software systems, and some statistical relationships exist among these metrics. Extracting the information of these metrics from the monitoring data and then analyzing the relationships between these metrics is an effective way to detect failure and diagnose fault. This paper proposes a fault analysis approach for the system at runtime which gets the information of the system by monitoring. We demonstrate this approach in a case study which shows that our approach is effective and is beneficial to find the relationship between the fault and the component.
<scp>DNA</scp> Repair (2003)

Abstract When the DNA in cells is damaged by chemical or physical agents, such as ultraviolet light, the damage can lead to DNA mutations or even cell death. Cells use various DNA‐repair proteins to fix any damage and to prevent damage‐induced mutations and killing.
Dextromethorphan Protects Retina Against Ischemic Injury In Vivo (1989)

Retinal ischemia was induced in rabbits by increasing intraocular pressure above systolic blood pressure for 60 or 75 minutes, and retinal function was monitored by electroretinography. Pretreatment with intravenous dextromethorphan, a nonprescription antitussive and selective antagonist of N-methyl-D-aspartate receptors, enhanced greatly the post-ischemic recovery of b-wave amplitude. Dextromethorphan may prove to be useful clinically in the management of retinal ischemic disease.
Transforming Growth Factor-β1 Inhibits Pseudoaneurysm Formation After Aortic Patch Angioplasty (2017)

Normal healing after aortic patch angioplasty is associated with increased TGF-β1 signaling, and recruitment of smad2 signaling may limit pseudoaneurysm formation; loss of TGF-β1 signaling is associated with the formation of large pseudoaneurysms. Enhancement of TGF-β1 signaling may be a potential mechanism to limit pseudoaneurysm formation after vascular intervention.
Dynamic code duplication with vulnerability awareness for soft error detection on VLIW architectures (2013)

Soft errors are becoming a critical concern in embedded system designs. Code duplication techniques have been proposed to increase the reliability in multi-issue embedded systems such as VLIW by exploiting empty slots for duplicated instructions. However, they increase code size, another important concern, and ignore vulnerability differences in instructions, causing unnecessary or inefficient protection when selecting instructions to be duplicated under constraints. In this article, we propose a compiler-assisted dynamic code duplication method to minimize the code size overhead, and present vulnerability-aware duplication algorithms to maximize the effectiveness of instruction duplication with least overheads for VLIW architecture. Our experimental results with SoarGen and Synopsys simulation environments demonstrate that our proposals can reduce the code size by up to 40% and detect more soft errors by up to 82% via fault injection experiments over benchmarks from DSPstone and Livermore Loops as compared to the previously proposed instruction duplication technique.
Noninvasive optimization of left ventricular filling using esophageal Doppler (1991)

Esophageal Doppler measurement of aortic blood flow can be used for rapid, noninvasive optimization of LV filling in mechanically ventilated patients.
Update on physical state of bile. (1995)

Because of recent assertions by a group of investigators that structures called "lamellae" instead of mixed micelles are present in human bile, the nature of biliary cholesterol solubilization and transport ("carriage") has again become a matter of dispute. "Lamellae" are rod- or tubular- shaped banded images observed when biles are negatively stained and dehydrated during electron microscopy; they are believed to be composed principally of biliary phospholipid (which is mostly lecithin) and cholesterol. It is well known that when mixed together in aqueous systems, lecithin and cholesterol, which are otherwise insoluble amphiphilic lipids, swell to form stacked or multilamellar liquid crystals that have regular periodicity because of the bilayer arrangement of the molecules. Provided super-micellar concentrations of cholesterol are present, multilamellar vesicles occur spontaneously in concentrated model biles, and are a frequent occurrence in human gallbladder biles that are beginning to nucleate cholesterol crystals. When multilamellar vesicles are negatively stained and dehydrated, they produce "lamellae" images by electron microscopy. Coincidentally, images of "lamellae" are also produced when purely micellar bile, either model or native is treated similarly. In this review we show that these images are an artifact. This artifact is produced by the dehydration process itself and is due to a phase change i.e. a change in molecular packing which is predicted by the appropriate phase diagram. As a consequence, a dehydrated "lamellae" phase results and the overall effect is an electron microscopic image that is identical to those produced by multilamellar vesicles in supersaturated or lithogenic biles.(ABSTRACT TRUNCATED AT 250 WORDS)
Immunologic Abnormalities Accompanying Acute and Chronic Viral Infections (1991)

A number of viral infections induce profound alterations in immune function; these changes may or may not be related to direct infection of lymphoid cells. The immunologic abnormalities that occur during acute systemic viral infections such as measles or infectious mononucleosis include suppression of responses to tuberculin skin tests in vivo and suppression of mitogen responses in vitro, evidence of activation of the immune system with up-regulation of activation-associated cell-surface markers and soluble cellular products, and evidence of altered immune regulation with autoimmune disease and elevated IgE. These abnormalities are likely to be interrelated and can become chronic when the viral infection is not cleared and persists.
<i>APOL1</i> and Kidney Disease: From Genetics to Biology (2019)

Genetic variants in the <i>APOL1</i> gene, found only in individuals of recent African ancestry, greatly increase risk of multiple types of kidney disease. These <i>APOL1</i> kidney risk alleles are a rare example of genetic variants that are common but also have a powerful effect on disease susceptibility. These alleles rose to high frequency in sub-Saharan Africa because they conferred protection against pathogenic trypanosomes that cause African sleeping sickness. We consider the genetic evidence supporting the association between <i>APOL1</i> and kidney disease across the range of clinical phenotypes in the <i>APOL1</i> nephropathy spectrum. We then explore the origins of the <i>APOL1</i> risk variants and evolutionary struggle between humans and trypanosomes at both the molecular and population genetic level. Finally, we survey the rapidly growing literature investigating APOL1 biology as elucidated from experiments in cell-based systems, cell-free systems, mouse and lower organism models of disease, and through illuminating natural experiments in humans.