gebhart/patrepeval huggingface dataset:
Single step current driven routing of multiterminal signal nets for analog applications (2000)

Article Single step current driven routing of multiterminal signal nets for analog applications Share on Authors: Thorsten Adler Infineon Technologies, AG Infineon Technologies, AGView Profile , Erich Barke Institute of Microelectronic Systems, University of Hanover, Germany Institute of Microelectronic Systems, University of Hanover, GermanyView Profile Authors Info & Claims DATE '00: Proceedings of the conference on Design, automation and test in EuropeJanuary 2000 Pages 446–450https://doi.org/10.1145/343647.343817Online:01 January 2000Publication History 12citation153DownloadsMetricsTotal Citations12Total Downloads153Last 12 Months3Last 6 weeks0 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteGet Access
The Molecular Basis of Self-Association of IgG-Rheumatoid Factors (1975)

The intermediate complexes, sedimenting between 19S and 6.6S components of normal serum on analytical ultracentrifugation, were purified from plasma of three patients with rheumatoid arthritis. Sequential gel filtration and removal of contaminants by agarose-antibody immunoadsorbents were employed for purification of these complexes. The isolated complexes from the three patients consisted of IgG with k and lambda light chains. Sedimentation equilibrium ultracentrifugation experiments showed that the isolated complexes underwent concentration-dependent self-association, whereby the smallest detectable molecular species had a molecular weight of 292,000. These IgG dimers were formed by self-association of IgG-rheumatoid factors, since nearly all F(ab) fragments, prepared from the isolated complexes by pepsin digestion, bound to normal IgG. The association constants for the interaction between normal IgG and one binding site of the F(ab) fragments were about 10-5 liters/mole. Since a cyclic structure with two antigen-antibody bonds was thought to form in the self-association of two IgG-rheumatoid factors, the association constant for dimer formation was calculated to be 10-10 liters/mole. The preferential self-association of IgG-rheumatoid factor was supported by the observation that monomeric normal human IgG did not replace the IgG-rheumatoid factor when the complexes were dissociated and reformed in the presence of excess normal IgG. The self-association of IgG-rheumatoid factors may be a general phenomenon in rheumatoid arthritis, as suggested by the observations of other investigators.
Evaluation of Two Fast and Easy Methods for Pesticide Residue Analysis in Fatty Food Matrixes (2005)

Two rapid methods of sample preparation and analysis of fatty foods (e.g., milk, eggs, and avocado) were evaluated and compared for 32 pesticide residues representing a wide range of physicochemical properties. One method, dubbed the quick, easy, cheap, effective, rugged, and safe (QuEChERS) method for pesticide residue analysis, entailed extraction of 15 g sample with 15 mL acetonitrile (MeCN) containing 1% acetic acid followed by addition of 6 g anhydrous magnesium sulfate and 1.5 g sodium acetate. After centrifugation, 1 mL of the buffered MeCN extract underwent a cleanup step (in a technique known as dispersive solid-phase extraction) using 50 mg each of C18 and primary secondary amine sorbents plus 150 mg MgSO4. The second method incorporated a form of matrix solid-phase dispersion (MSPD), in which 0.5 g sample plus 2 g C18 and 2 g anhydrous sodium sulfate was mixed in a mortar and pestle and added above a 2 g Florisil column on a vacuum manifold. Then, 5 x 2 mL MeCN was used to elute the pesticide analytes from the sample into a collection tube, and the extract was concentrated to 0.5 mL by evaporation. Extracts in both methods were analyzed concurrently by gas chromatography/mass spectrometry and liquid chromatography/tandem mass spectrometry. The recoveries of semi-polar and polar pesticides were typically 100% in both methods (except that basic pesticides, such as thiabendazole and imazalil, were not recovered in the MSPD method), but recovery of nonpolar pesticides decreased as fat content of the sample increased. This trend was more pronounced in the QuEChERS method, in which case the most lipophilic analyte tested, hexachlorobenzene, gave 27 +/- 1% recovery (n=6) in avocado (15% fat) with a<10 ng/g limit of quantitation.
The Effect of Tumor Necrosis Factor on Human Sperm Motility <i>In Vitro</i> (1989)

Tumor necrosis factor (TNF alpha) is present in elevated levels in peritoneal fluid from infertile women with endometriosis. The effect of TNF alpha on human sperm motility in vitro was evaluated utilizing peritoneal fluid from infertile women with minimal endometriosis containing 0, 100, 400, or 800 U of TNF alpha/ml as well as similar concentrations of recombinant human TNF alpha. No reduction in progressive and total motility was found at recombinant TNF alpha concentrations of 100 U ml. However, 500 and 1000 U of recombinant TNF alpha/ml caused a significant reduction in progressive and total sperm motility after 4 and 21 hours of incubation when compared with controls. Similarly, peritoneal fluid containing 100 U of TNF alpha/ml did not significantly reduce progressive and total sperm motility after either 4 or 21 hours of incubation; but peritoneal fluid containing 400 U of TNF alpha/ml reduced progressive sperm motility after 4 and 21 hours and total sperm motility after 21 hours of incubation. Peritoneal fluid with a TNF alpha concentration of 800 U/ml caused a significant reduction in both progressive and total sperm motility after 4 and 21 hours when compared with controls of TNF alpha-negative peritoneal fluid. The addition of polyclonal rabbit anti-TNF alpha antibody or 30-min heat inactivation at 56 C of TNF alpha-positive peritoneal fluid reversed the inhibitory effect on sperm motility. The ability of TNF alpha to cause a significant reduction of sperm motility in vitro suggests that this may be a mechanism for the infertility observed in women with minimal endometriosis.
The Past and Future of Neuroprotection in Cerebral Ischaemic Stroke (2007)

Following the realization that cerebral tissue may survive for hours after an ischaemic insult, several agents with neuroprotective properties in small-animal models of cerebral ischaemia have been tested in patients with acute ischaemic stroke (AIS). Initial attempts at translating the positive effects of these agents from animal models to patients were unsuccessful, possibly as a result of poorly planned experiments in models of ischaemia, and/or clinical trials of AIS that were not optimized to show a positive effect. Newer neuroprotective agents that are believed to act later in the ischaemic cascade may offer a greater chance of success. However, before these agents can be introduced into clinical practice they must undergo assessment in rodent and large-animal models of AIS and, in particular, the dose-response relationship and the treatment time window should be defined. This should be followed by evaluation in carefully designed clinical trials of adequate power, involving subjects receiving an appropriate dose within an optimum time window following the onset of symptoms. There is hope that such careful strategies may guide continued progress in neuroprotective drug development.
Heat‐Shock Protein Gene Expression in Diploid Wheat Genotypes Differing in Thermal Tolerance (1992)

Under high temperature stress, plants synthesize a set of proteins called heat‐shock proteins (HSPs). The objective of this research was to investigate HSP gene expression in two diploid wheat ( Triticum monococcum L., 2n = 2x = 14) genotypes differing in thermal tolerance. Genotypes M3 (tolerant) and M9 (susceptible) were determined to be significantly different in acquired thermal tolerance based on the following criteria: reduction in regrowth during recovery from heat stress, reduction in chlorophyll content, and 2,3,5,‐triphenyltetrazolium chloride reduction after 12 h of heat hardening prior to a normally lethal heat treatment. Electron micrographs revealed that the cellular ultra structure of M3 was more thermally stable than that of M9 after only 2 h of heat hardening prior to a normally lethal heat treatment. Two.dimensional analysis of in vitro translated heat shock proteins revealed no observable qualitative differences in the HSP profile between the two genotypes. Northern analysis using HSP cDNAs 16.9, 26, and 70 as probes, indicated that M3 had higher steady state levels of HSP mRNA than M9 during the 2‐h heat hardening. The results suggest that acquired thermal tolerance in wheat is correlated with the level of heat‐shock gene expression during the first 2 h of heat stress.
Voice Biometric Authentication for Enhancing Internet Service Security (2006)

Although many customer-oriented Internet applications, such as Web-banking or e-commerce, are being widely used, an increased security level is required. An efficient means to this end is by authenticating users through biometric methods. In this work, the architecture of an Internet application deploying voice biometric authentication is presented. Among the existing biometric methods, voice biometrics can be an affordable and accurate authentication technology that has been already successfully employed in telephony services. According to the proposed architecture, a transaction-based Internet application should be complemented by a biometric server where customer's unique set of speech models (voiceprint) is stored. The authentication procedure requests from the user to pronounce a random sequence of digits and after capturing speech and extracting voice features at the client side are sent back to the biometric server. The biometric server decides whether the received features match the stored voiceprint of the customer who claims to be, and accordingly grants authentication. By implementing the proposed architecture, Internet applications are provided by a higher degree of certainty regarding the identity of a customer, and prevented from fraudulent transactions
Effect of Shear on Polymer Aided Flocculation of Suspensions (1978)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTEffect of Shear on Polymer Aided Flocculation of SuspensionsNicholas D. Sylvester and Mousa P. ToureCite this: Ind. Eng. Chem. Prod. Res. Dev. 1978, 17, 4, 347–351Publication Date (Print):December 1, 1978Publication History Published online1 May 2002Published inissue 1 December 1978https://doi.org/10.1021/i360068a012RIGHTS & PERMISSIONSArticle Views139Altmetric-Citations9LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (669 KB) Get e-Alerts
Immunocytochemical staining of fine-needle aspiration biopsies of the liver as a diagnostic tool for hepatocellular carcinoma. (1992)

Fine-needle aspiration biopsy (FNAB) under ultrasonographic or computerized tomographic guidance is a useful diagnostic procedure for hepatic neoplasms. However, cytologic criteria alone may not allow for the distinction of hepatocellular carcinomas (HCC) from cholangiocarcinomas (CC) and metastatic adenocarcinomas (MA). In an effort to refine the FNAB diagnosis of hepatic malignancies, a panel of immunocytochemical stains was applied to aspiration specimens from primary and metastatic carcinomas in the liver. Anticytokeratin antibodies with different specificities (Cam 5.2 and AE1) were used in conjunction with antibodies to carcinoembryonic antigen (CEA), alpha-fetoprotein (AFP), and alpha-1-antitrypsin (AAT). All HCC, CC, and MA were immunoreactive with the antikeratin antibody Cam 5.2. However, only three (15%) HCC were positive with AE1, in contrast to 100% of CC and MA. Antibodies to CEA and AFP were also helpful diagnostic aids, especially for the three HCC that were immunoreactive with AE1. Canalicular staining for CEA was present in 47% of HCC, but in none of the CC or MA. AFP positivity occurred in 45% of HCC, but only one CC and none of the MA. AAT was not a useful marker for HCC due to low sensitivity and specificity. Immunocytochemistry is an effective adjunct to the cytodiagnosis of malignant liver tumors sampled by FNAB.
從五古的敘述節奏看杜甫"詩中有文"的創變 (2016)

杜甫在初盛唐五言普遍受宋齊體調影響的背景下，解決了使中長篇五古恢復漢魏古調的問題，因而是唐代五古繼陳子昂之後的又一重大轉關。但杜甫並非簡單地從形式格調模擬漢魏，也不是像盛唐詩人那樣通過規避近體聲律來創作古詩，而是在追溯漢魏古詩創作原理的基礎上，從當代生活語言中提煉新的五古節奏。在化用漢魏式的比興、句法和章法的同時，他更注重學習漢魏古詩善於概括人情之常的特徵，並且深入發掘五古以單行散句敘述的潛力，加大連貫敘述的密度和句段節奏的緊湊感，探索了在詩歌中展開敘述的多種表現方式，從而形成了“詩中有文”的重要特色。且杜甫既使五言古詩本來便於敘述的特長在中長篇中得到最大程度的發揮，又通過抒情節奏的主導嚴格把握了詩與文的基本界線。杜詩之所以能成爲“詩史”，五古的這一重要創變也爲其提供了體制的極大便利。
Prognostics and Health Management A Data-Driven Approach to Supporting the F-35 Lightning II (2007)

The Joint Strike Fighter (JSF) Program has developed an aggressive vision for and has specified a very stringent set of requirements for a comprehensive Prognostics and Health Management (PHM) system. This vision and the associated specified requirements has resulted in the development of perhaps the most advanced and comprehensive set of diagnostic, prognostic, and health management capabilities yet to be applied to an aviation platform. These PHM capabilities are currently being developed and integrated into the JSF Air System design. This paper will provide a top level overview summary of the current PHM concept, design, and architecture; provide a general capabilities description; and discuss overall program status. Some specific examples of system benefits, design trade-off decisions, and system integration challenges will be discussed. Particular examples of some subsystem prognostic capabilities will also be discussed.
SIMILARITY OF DOCUMENTS AND DOCUMENT COLLECTIONS USING ATTRIBUTES WITH LOW NOISE (2007)

In this paper, a unified framework for clustering documents based on vocabulary overlap and in-link similarity is presented. A small number of non-zero attributes per document, taken from a very large set of possible attributes, ensure efficient comparisons procedures. We show that A) low frequent words are excellent attributes for textual documents as well as B) sources of in-links as attributes for web documents. In the cases of web documents, co-occurrence analysis is used to identify similarity. The documents are represented as nodes in a graph with edges weighted by similarity. A graph clustering algorithm is applied to group similar documents together. Evaluation for textual documents against a gold standard is provided.
Effect of Fatty Acids and Cholesterol Present in Bile on Expression of Virulence Factors and Motility of <i>Vibrio cholerae</i> (2007)

Bile induces pleiotropic responses that affect production of virulence factors, motility, and other phenotypes in the enteric pathogen Vibrio cholerae. Since bile is a heterogeneous mixture, crude bile was fractionated, and the components that mediate virulence gene repression and enhancement of motility were identified by nuclear magnetic resonance, gas chromatography (GC), and GC-mass spectrometry analyses. The unsaturated fatty acids detected in bile, arachidonic, linoleic, and oleic acids, drastically repressed expression of the ctxAB and tcpA genes, which encode cholera toxin and the major subunit of the toxin-coregulated pilus, respectively. The unsaturated fatty acid-dependent repression was due to silencing of ctxAB and tcpA expression by the histone-like nucleoid-structuring protein H-NS, even in the presence of the transcriptional activator ToxT. Unsaturated fatty acids also enhanced motility of V. cholerae due to increased expression of flrA, the first gene of a regulatory cascade that controls motility. H-NS had no role in the fatty acid-mediated enhancement of motility. It is likely that the ToxR/ToxT system that negatively regulates motility is rendered nonfunctional in the presence of unsaturated fatty acids, leading to an increase in motility. Motility and flrA expression were also increased in the presence of cholesterol, another component of bile, in an H-NS- and ToxR/ToxT-independent manner.
Merging metabolomics and lipidomics into one analytical run (2018)

A novel integrated metabolomics/lipidomics workflow is introduced enabling high coverage of polar metabolites and non-polar lipids within one analytical run. Dual HILIC and RP chromatography were combined to high-resolution mass spectrometry. As a major advantage, only one data file per sample was obtained by fully automated simultaneous analysis of two extracts per sample. Hence, the unprecedented high coverage without compromise on analytical throughput was not only obtained by the orthogonality of the chromatographic separations, but also by the implementation of dedicated sample preparation procedures resulting in optimum extraction efficiency for both sub-omes. Thus, the method addressed completely hydrophilic sugars and organic acids next to water-insoluble triglycerides. As for the timing of the dual chromatography setup, HILIC and RP separation were performed consecutively. However, re-equilibration of the HILIC column during elution of RP compounds and vice versa reduced the overall analysis time by one third to 32 min. Application to the Standard Reference Material SRM 1950 - Metabolites in Frozen Human Plasma resulted in >100 metabolite and >380 lipid identifications based on accurate mass implementing fast polarity switching and acquiring data dependent MS2 spectra with the use of automated exclusion lists. Targeted quantification based on external calibrations and 13C labeled yeast internal standards was successfully accomplished for 59 metabolites. Moreover, the potential for lipid quantification was shown integrating non-endogenous lipids as internal standards. In human plasma, concentrations ranging over 4 orders of magnitude (low nM to high μM) were assessed.
[The periareolar approach management of postoperative complications of breast augmentation by injected polyacrylamide hydrogel]. (2005)

Polyacrylamide hydrogel should be prohibited for injected breast augmentation at present. A double-blinded randomized clinical study, controlled animal experiments and a large sample questionnaire survey for complications are necessary. The periareolar approach is valuable technique and can remove polyacrylamide hydrogel as completely as possible.
Diffusion cell for the preparation of dilute vapor concentrations (1975)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTDiffusion cell for the preparation of dilute vapor concentrationsAntonio H. Miguel and David F. S. NatuschCite this: Anal. Chem. 1975, 47, 9, 1705–1707Publication Date (Print):August 1, 1975Publication History Published online1 May 2002Published inissue 1 August 1975https://pubs.acs.org/doi/10.1021/ac60359a015https://doi.org/10.1021/ac60359a015research-articleACS PublicationsRequest reuse permissionsArticle Views109Altmetric-Citations26LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
B0-fluctuation-induced temporal variation in EPI image series due to the disturbance of steady-state free precession (2000)

Steady-state free precession (SSFP) can develop under a train of RF pulses, given the condition TR < T(2). SSFP in multi-shot imaging sequences has been well studied. It is shown here that serial single-shot echo-planar imaging (EPI) acquisition can also develop SSFP, and the SSFP can be disturbed by B(0) fluctuation, causing voxel-wise temporal variation. This SSFP disturbance is predominantly present in cerebrospinal fluid (CSF) regions due to the long T(2) value. By applying a sufficiently strong crusher gradient in the EPI pulse sequence, the temporal variation induced by SSFP disturbance can be suppressed due to diffusion. Evidence is provided to indicate that physiological motions such as cardiac pulsation and respiration could affect the voxel-wise time courses through the mechanism of SSFP disturbance. It is advised that if the disturbance is observed in serial EPI images, the crusher should be made stronger to eliminate the unwanted temporal variation.
Cooccurrence of Multiple AmpC β-Lactamases in Escherichia coli, Klebsiella pneumoniae, and Proteus mirabilis in Tunisia (2015)

Over a period of 40 months, plasmid-mediated AmpC β-lactamases were detected in Tunis, Tunisia, in 78 isolates (0.59%) of Escherichia coli, Klebsiella pneumoniae, and Proteus mirabilis. In 67 isolates, only one ampC gene was detected, i.e., blaCMY-2-type (n = 33), blaACC (n = 23), blaDHA (n = 6) or blaEBC (n = 5). Multiple ampC genes were detected in 11 isolates, with the following distribution: blaMOX-2, blaFOX-3, and blaCMY-4/16 (n = 6), blaFOX-3 and blaMOX-2 (n = 3), and blaCMY-4 and blaMOX-2 (n = 2). A great variety of plasmids carrying these genes was found, independently of the species and the bla gene. If the genetic context of blaCMY-2-type is variable, that of blaMOX-2, reported in part previously, is unique and that of blaFOX-3 is unique and new.
Background Subtraction for Moving Object Detection in RGBD Data: A Survey (2018)

The paper provides a specific perspective view on background subtraction for moving object detection, as a building block for many computer vision applications, being the first relevant step for subsequent recognition, classification, and activity analysis tasks. Since color information is not sufficient for dealing with problems like light switches or local gradual changes of illumination, shadows cast by the foreground objects, and color camouflage, new information needs to be caught to deal with these issues. Depth synchronized information acquired by low-cost RGBD sensors is considered in this paper to give evidence about which issues can be solved, but also to highlight new challenges and design opportunities in several applications and research areas.