gebhart/patrepeval huggingface dataset:
Contaminant dispersal in bounded turbulent shear flow (1995)

The dispersion of smoke downstream of a line source at the wall and at y{sup +} = 30 in a turbulent boundary layer has been predicted with a non-local model of the scalar fluxes {bar u}c and {bar v}c. The predicted plume from the wall source has been compared to high Schmidt number experimental measurements using a combination of hot-wire anemometry to obtain velocity component data synchronously with concentration data obtained optically. The predicted plumes from the source at y{sup +} = 30 and at the wall also have been compared to a low Schmidt number direct numerical simulation. Near the source, the non-local flux models give considerably better predictions than models which account solely for mean gradient transport. At a sufficient distance downstream the gradient models gives reasonably good predictions.
Analysis of multipoint videoconferencing under reroutable route-configuration assignment (1998)

In this paper, we study the use of reroutable assignment for multipoint videoconferences in a high-speed network. A conference model is constructed and conference calls are classified. A conference of a particular type can ride on different route-configurations. According to the location of the current speaker, a conference has different modes of operation. Two network management functions are discussed: call admission ensures a preset quality-of-service requirement by blocking new calls that causes congestion; route-configuration assignment determines the multicast tree for distributing the video of the current speaker. The reroutable route-configuration assignment is introduced. It allows a change of route-configuration when there is a change of speaker. Two reroutable assignment schemes are studied. In the normal scheme, a conference is always rerouted to the least congested route-configuration; while in the sticky scheme, a conference is only rerouted when the current route-configuration is congested. The video freeze probability, rerouting probability and the extended capacity space are derived. An example shows that the video freeze probabilities of the two schemes do not differ significantly. The sticky scheme, however, is superior as it gives a much smaller rerouting probability than the normal scheme. © 1998 John Wiley & Sons, Inc.
Large-Signal Response of p-i-n Photodetectors Using Short Pulses With Small Spot Sizes (2004)

In this paper, the response of a surface-normal p-i-n photodetector that was incorporated in an optically controlled optical gate was analyzed using short-pulsed, high-energy optical inputs with small spot sizes. Simulation results based in part on diffusive conduction were compared against the experimental data, providing an understanding of the device response. Results also demonstrated that p-i-n photodetectors may be designed so that reducing the spot size, counterintuitively, results in negligible additional field screening.
Oxidative Addition of MeI to a Rollover Complex of Platinum(II): Isolation of the Kinetic Product (2013)

A pair of new Pt(II)/Pt(IV) 2,2′-bipyridine cyclometalated rollover complexes have been synthesized and characterized. [Pt(bpy-H)(CH3)(PMe3)] (1), where bpy-H = κ2N,C-2,2′-bipyridine, was obtained from the electron-rich precursor cis-[Pt(CH3)2(DMSO)2] with a one-pot, two step synthesis; its reactivity has been tested with CH3I, giving the corresponding Pt(IV) complex cis-[Pt(bpy-H)(CH3)2(I)(PMe3)] (2), which was fully characterized. Crystals suitable for X-ray analysis were obtained and allowed the determination of the structure of isomer 2A which is the product of the trans addition of CH3I, usually thought of as the kinetic product.
Selecting among replicated batching video-on-demand servers (2002)

A Video-on-Demand (VoD) service offers a large selection of videos from which customers can choose. Designers of VoD systems strive to achieve low access latency for customers. One approach that has been investigated by several researchers allows the server to batch clients requesting the same video and to serve clients in the same batch with one multicast video stream. This approach has the advantage that it can save server resources as well as server access and network bandwidth, thus allowing the server to handle a large number of customers without sacrificing access latency. VoD server replication is another approach that can allow a VoD service to handle a large number of clients, albeit at the additional cost of providing more servers. While replication is an effective way to increase the service capacity, it needs to be coupled with appropriate selection techniques in order to make efficient use of the increased capacity. In this paper, we investigate the design of server selection techniques for a system of replicated batching VoD servers. We design and evaluate a range of selection algorithms as they would be applied to three batching approaches: Batching with Persistent Channel Allocation, Patching, and Hierarchical Multicast Stream Merging (HMSM). We demonstrate that server replication combined with appropriate server selection scheme can indeed be used to increase the capacity of the service leading to improved performance.
RADIOIMMUNOASSAY OF STEROIDS (1970)

ABSTRACT A number of radioimmunoassay systems have been developed for quantitation of a variety of steroid hormones. Suitable antisera were obtained by immunizing rabbits with steroid derivatives conjugated at various positions to bovine serum albumin. The specificity of the antisera varied directly with the position of conjugation. Changes in the latter resulted in greater than 2000-fold shifts in relative inhibitory activity for a given steroid. The data indicate that conjugation should be done through a region (such as position 6) that is remote from distinguishing functional groups. The specificity data and nature of the inhibition curves suggest that the major portion of the steroid molecule is being recognized as a single immunoreactive unit. The advantages and problems associated with use of radioiodinated conjugates for labeled steroids are discussed. With conjugates, it has been possible to quantitate reliably as little as one pg of some steroids in a single assay tube.
Delayed Hypersensitivity (1968)

Summary Transfer of sensitized cells to normal guinea pigs was used to study persistence and conjugate specificity of delayed hypersensitivity. Ability of donor cells to transfer delayed hypersensitivity persisted throughout the primary and secondary antibody responses of the donor animals. The skin reactions elicited in recipients of cells from hyperimmunized guinea pigs remained conjugate specific throughout the immune response.
Molecular Cloning of 114/A10, a Cell Surface Antigen Containing Highly Conserved Repeated Elements, Which Is Expressed by Murine Hemopoietic Progenitor Cells and Interleukin-3-dependent Cell Lines (1989)

Monoclonal antibody 114/A10, raised against the murine multipotential hemopoietic progenitor cell line B6SUtA, identifies an antigen highly expressed by primary myeloid progenitor cells, the myelomonocytic leukemia cell line WEHI-3, and various interleukin-3 (IL-3)-dependent cell lines. Western blotting studies indicate that the 114/A10 antigen has a mean relative molecular mass of 150,000 but varies greatly in size range between different cell types. cDNA clones encoding this protein were isolated from a plasmid-based expression vector library prepared from B6SUtA RNA. Three clones corresponding in size to the two major mRNA species detected in IL-3-dependent cell lines (3.0 and 2.2 kilobase pairs) and differing in their utilization of alternative polyadenylation signals were obtained. These clones contain a single long open reading frame of 573 amino acids possessing the typical characteristics of an integral membrane protein. A particularly striking feature of this sequence is the presence at the extracellular amino terminus of a series of eight highly conserved 27-amino acid, serine/threonine-rich (55%) tandem repeats that may serve as sites of extensive glycosylation. The extracellular domain also contains three epidermal growth factor-like cysteine-rich repeats. The distribution and structural characteristics of the 114/A10 antigen suggest a possible regulatory role in the cellular response to IL-3.
Transurethral Hyperthermia for Benign Prostatic Hyperplasia Patients with Retention (1992)

From 1989 to 1990, 32 poor surgical risk patients with urinary retention were treated with transurethral microwave hyperthermia at the department of urology, University of Leuven in Belgium. Mean patient age was 73 years (range 58 to 90 years) and mean duration of retention was 4 weeks (range 3 to 12 weeks). Followup ranged from 13 to 82 weeks, with a mean of 31 weeks. Bilobar or trilobar hyperplasia was diagnosed in 25 patients (78%), while 7 (22%) had median lobe or median bar hypertrophy. The mean prostatic volume was 52 cc (range 25 to 150 cc). Transurethral microwave hyperthermia was given with a helical antenna at 915 MHz. once or twice per week. The mean number of transurethral microwave hyperthermia sessions was 8.9 (range 5 to 10). Each session consisted of a 60-minute treatment at a mean maximum temperature of 45.4C (range 43.7 to 47.2C), average temperature 43.9C (range 42.7 to 45.5C) and minimum temperature 42.0C (range 40.2 to 43.0C). The temperature was continuously monitored, including thermal mapping in all patients. Of the 25 patients who presented with bilobar or trilobar hyperplasia 18 (72%) were catheter-free for the duration of followup. Of the 7 median lobe or median bar patients 1 (14%) showed sufficient improvement to warrant catheter removal. This patient, however, had recurrent retention 4 months after transurethral microwave hyperthermia. In patients with bilobar and trilobar hyperplasia a strong correlation was observed among maximum temperature (p = 0.0006), average temperature (p = 0.0033) and treatment response. As expected, no such correlation existed between minimum temperature and response to treatment (p = 0.56). Our study has again demonstrated therapeutic activity in patients with benign prostatic hyperplasia treated with transurethral microwave hyperthermia. A new finding was a strong correlation between temperature and response.
Belastungsuntersuchungen in der Pneumologie – Empfehlungen der Deutschen Gesellschaft für Pneumologie und Beatmungsmedizin e. V. (2018)

This document replaces the DGP recommendations published in 1998 and 2013. Based on recent studies and a consensus conference, the indications, choice and performance of the adequate exercise testing method and its necessary technical and staffing setting are discussed. Detailed recommendations are provided: for blood gas analysis and right heart catheterization during exercise, walk tests, spiroergometry, and stress echocardiography. The correct use of different exercise tests is discussed for specific situations in respiratory medicine: exercise induced asthma, obesity, monitoring of rehabilitation or therapeutical interventions, preoperative risk stratification, and evaluation in occupational medicine.
<sup>31</sup> P Nuclear Magnetic Resonance Spectroscopic Imaging of Regions of Remodeled Myocardium in the Infarcted Rat Heart (1995)

31P CSI of post-MI hearts shows that (1) PCr decreases uniformly (ie, independent of the distance from the scar) in the noninfarcted remodeled myocardium, and its amount inversely correlates with infarct size; and (2) the ATP signal provides a profile of viable myocardium and is a biochemical marker of morphological remodeling and hypertrophy that has occurred in noninfarcted regions. Thus, 31P CSI provides both a marker that tissue injury has occurred (decreased PCr) and a marker of the extent of remodeling in response to injury (ATP distribution) in a single set of noninvasive measurements.
Differential vasodilator properties of KRN2391, cromakalim, nitroglycerin and nifedipine in rabbit isolated femoral artery and vein (1994)

1. The selectivity for artery and vein of KRN2391, cromakalim, nitroglycerin and nifedipine was examined in isolated femoral artery and vein preparations of the rabbit. 2. All drugs produced a concentration-dependent relaxation in both femoral artery and vein. 3. Nitroglycerin was more potent in femoral vein than in femoral artery at all concentrations. The EC50 value obtained in the vein was about 14 times smaller than that obtained in artery. 4. Cromakalim and nifedipine were almost equipotent on both vascular preparations. Cromakalim at the highest concentration (10(-5) M) produced 88 and 78% relaxation in femoral artery and vein, respectively. The maximum relaxation induced by nifedipine (10(-6) M) was less than 50% in both preparations. 5. KRN2391 was active at a lower concentration in the vein than in the artery and its maximum relaxation at 10(-5) M was about 90% in both preparations. 6. Glibenclamide (10(-6) M) inhibited the vasorelaxation caused by KRN2391 in both artery and vein. Methylene blue (10(-5) M) also inhibited the relaxant action of KRN2391 but this action was slight in the artery. 7. These results suggest that KRN2391 and nitroglycerin are more potent in the vein than in the artery and cromakalim and nifedipine are equipotent in both. It is considered that the relaxation induced by low concentrations of KRN2391 reflects predominantly its action as a nitrate and that at high concentrations it acts as a K+ channel opener in addition to its nitrate action. The different vascular selectivities of these drugs are thought to relate to the differences in their mechanisms of action in vascular smooth muscle.
An Analysis of Cost Factors in Maintaining and Updating Card Catalogs (1969)

This study enumerates and compares costs of manual and computerized catalogs. The difficulties of making comparative cost studies are examined. The report concentrates on the problems of cost element definition and on the reporting of as many comparable sources as possible. Results of cost studies are presented in the form of tables that show comparative costs of cataloging, card processing, conversion, and manual and comput- erized processing. There are also tables on card catalog costs. Conclusions are that the costs of manual and automated methods are essentially the same for short entries, and that there is a substantial economic advantage for automated methods in full entries.
Weight Loss-Induced Plasticity of Glucose Transport and Phosphorylation in the Insulin Resistance of Obesity and Type 2 Diabetes (2003)

We tested the hypothesis that weight loss alleviates insulin resistance in skeletal muscle within the proximal steps of glucose metabolism, namely substrate delivery, glucose transport, and glucose phosphorylation. In obese subjects with and without type 2 diabetes, in vivo skeletal muscle assessments were obtained with dynamic positron emission tomography (PET) imaging performed during euglycemic clamps at moderate hyperinsulinemia (40 mU x min(-1) x m(-2)), using [(15)O]H(2)O and [(18)F]fluoro-deoxyglucose ([(18)F]FDG) to quantify tissue perfusion and glucose metabolism. Dynamic [(18)F]FDG PET data were analyzed using both a novel muscle-specific compartmental model and a compartmental model originally developed for the brain and often used for [(18)F]FDG muscle image quantification. Weight loss in obese subjects with (n = 9) and without (n = 9) type 2 diabetes over a 4-month intervention was substantial (14 +/- 2 kg, P < 0.05). Muscle insulin resistance, assessed by insulin-stimulated [(18)F]FDG uptake, decreased threefold in diabetic subjects and twofold in nondiabetic subjects (P < 0.001). Kinetic parameters for [(18)F]FDG transport and phosphorylation improved substantially in both groups, whereas tissue blood flow did not change. In particular, clinically significant weight loss fully corrected insulin resistance in type 2 diabetes at the step of glucose phosphorylation and largely, but incompletely, corrected insulin resistance at the glucose transport step.
The fear of dying and occurrence of posttraumatic stress symptoms after an acute coronary syndrome: A prospective observational study (2015)

The purpose of the study was to investigate whether experiencing fear of dying after acute coronary syndrome predicts later posttraumatic stress symptoms. We enrolled 90 patients hospitalized with main diagnosis of acute coronary syndrome and assessed baseline characteristics. One month after discharge, we collected the Posttraumatic Stress Scale. A total of 24 patients (26.7%) developed posttraumatic stress symptoms 1 month after the acute coronary syndrome event. Patients with posttraumatic stress symptoms reported significantly greater fear of dying, helplessness, avoidance-focused coping, and severe anxiety. In our prospective study, fear of dying was associated with occurrence of posttraumatic stress symptoms in patients hospitalized with acute coronary syndrome.
Mechanistic study of hydrogen activation by cationic dinuclear (.mu.-sulfido)molybdenum complexes. [Erratum to document cited in CA117(5):48806d] (1992)

ADVERTISEMENT RETURN TO ISSUEPREVArticleMechanistic study of hydrogen activation by cationic dinuclear (.mu.-sulfido)molybdenum complexes. [Erratum to document cited in CA117(5):48806d]Linda L. Lopez, P. Bernatis, J. Birnbaum, R. C. Haltiwanger, and M. Rakowski DuboisCite this: Organometallics 1992, 11, 11, 3928Publication Date (Print):November 1, 1992Publication History Published online1 May 2002Published inissue 1 November 1992https://pubs.acs.org/doi/10.1021/om00059a076https://doi.org/10.1021/om00059a076research-articleACS PublicationsRequest reuse permissionsArticle Views31Altmetric-Citations1LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Modulation-doped ZnSe/(Zn,Cd,Mn)Se quantum wells and superlattices (2000)

The fabrication of “magnetic” two-dimensional electron gases in modulation-doped ZnSe/Zn1−x−yCdxMnySe quantum wells and superlattices is described, with a focus on correlating growth conditions with low temperature transport, atomic force microscopy, and photoluminescence. Optimization of the growth parameters results in a two-fold increase in 0.3 K mobility (∼23 000 cm2/V s) for the host ZnCdSe two-dimensional electron gasses (2DEGs) and a similar relative increase for magnetic 2DEGs. The improved sample growth is applied to the fabrication of modulation doped, strained-layer magnetic superlattices containing up to 25 periods of moderately strained quantum wells, without significant reduction in mobility.
Low Prostate Concentration of Lycopene Is Associated with Development of Prostate Cancer in Patients with High-Grade Prostatic Intraepithelial Neoplasia (2014)

Prostate cancer (PC) is a frequent male malignancy and represents the second most diagnosed cancer in men. Since pre-cancerous lesions, i.e., the high-grade prostatic intraepithelial neoplasia (HGPIN), can be detected years before progression to PC, early diagnosis and chemoprevention are targeted strategies to reduce PC rates. Animal studies have shown that lycopene, a carotenoid contained in tomatoes, is a promising candidate for the chemoprevention of PC. However, its efficacy in humans remains controversial. The present study aimed to investigate the relevance of plasma and prostate concentration of lycopene after a lycopene-enriched diet in patients diagnosed with HGPIN. Thirty-two patients diagnosed with HGPIN were administered a lycopene-enriched diet (20-25 mg/day of lycopene; through 30 g/day of triple concentrated tomato paste) for 6 months. A 6-month follow-up prostate biopsy assessed progression to PC. Patients were classified into three groups according to the histopathological features of the 6-month follow-up biopsy results: prostatitis; HGPIN and PC. PSA and plasma lycopene levels were measured before and after the dietary lycopene supplementation. Prostatic lycopene concentration was only assessed after the supplementation diet. Only prostatic lycopene concentration showed significant differences between the three groups (p = 0.03). Prostatic lycopene concentration below a 1 ng/mg threshold was associated with PC at 6-month follow-up biopsy (p = 0.003). We observed no overall benefits from a 6-month lycopene supplementation, as the rate of HGPIN progression to PC in our population (9/32, 28%) was similar to rates reported in the literature. Baseline PSA levels also showed no significant changes after a lycopene-enriched diet. Our findings point to prostatic lycopene concentration as a promising biomarker of PC. Further prospective longitudinal studies are needed to assess the prognostic role of prostatic lycopene in PC.
Pyrroloquinoline quinone (PQQ) is the organic cofactor in soybean lipoxygenase‐1 (1988)

Treatment of soybean lipoxygenase‐1 (SLO) with phenylhydrazine (PH) induced inactivation and a maximum (350 nm) in the absorption spectrum of the enzyme. To detach the product having this absorption maximum, proteolysis was required. The product appeared to be the C(5) phenylhydrazone of pyrroloquinoline quinone (PQQ). Quantification showed that one covalently bound PQQ is present per enzyme molecule. Inspection of published spectroscopic data leads to the conclusion that the established cofactor of SLO, Fe, present as one ion per enzyme molecule, interacts with PQQ, the latter functioning as a terdentate ligand for the Fe ion (the N atom and COOH group of the quinoline ring together with the hydrated C(5) carbonyl group). If it is assumed that the substrate has two sites of interaction with this two‐cofactor complex, namely with the Fe ion and the C(5) carbonyl group of PQQ, the electron‐relay system generated very well explains the reported mechanistic features as well as inhibition effects of substrates with extended conjugation systems. The finding of PQQ in SLO is an additional indication that this cofactor is very versatile with respect to involvement in different types of redox reaction. A further implication might be that PQQ has been overlooked in other well‐known enzymes with an established cofactor but where the presence of this cofactor is unable to explain the mechanistic and spectroscopic features.
Modeling and Control of Legged Locomotion via Switching Max-Plus Models (2014)

We present a gait generation framework for multi-legged robots based on max-plus algebra that is endowed with intrinsically safe gait transitions. The time schedule of each foot liftoff and touchdown is modeled by sets of max-plus linear equations. The resulting discrete-event system is translated to continuous time via piecewise constant leg phase velocities; thus, it is compatible with traditional central pattern generator approaches. Different gaits and gait parameters are interleaved by utilizing different max-plus system matrices. We present various gait transition schemes and show that optimal transitions, in the sense of minimizing the stance time variation, allow for constant acceleration and deceleration on legged platforms. The framework presented in this paper relies on a compact representation of the gait space, provides guarantees regarding the transient and steady-state behavior, and results in simple implementations on legged robotic platforms.