gebhart/patrepeval huggingface dataset:
Genetic study on male patients with infertility (2011)

Objective:To find out the genetic basis of male infertility and diagnose AZF gene in Y chromosome among male infertile patients,provide a theoretical basis for carrying out assisted reproductive technology targeting to infertile men.Methods:83 patients with primary azoospermia and oligozoospermia were selected,then lymphocytes culture and chromosomal karyotype analysis in peripheral blood were carried out,multiplexed PCR was used to detect 15 STS loci microdeletion in AZF region of Y chromosome;30 men with normal fertility were selected as control group.Results:13 patients were found with chromosomal abnormality,including 7 patients with azoospermia,accounting for 53.8%(7/13);6 patients with oligozoospermia,accounting for 46.2%(6/13),and 1 patient was found with microdeletion in AZFb+AZFc regions.Among 70 azoospermia and oligozoospermia patients with normal chromosomal karyotype,8 patients were found with microdeletion of AZF gene,2 patients were found with microdeletion of AZFa region,the proportion of microdeletion was 25.0%(2/8);1 patient was found with microdeletion of AZFb region,accounting for 12.5%(1/8);2 patients were found with microdeletion of AZFc region,accounting for 25.0%(2/8);1 patient was found with microdeletion of AZFb+ AZFc regions,accounting for 12.5%(1/8);1 patient was found with microdeletion of AZFb+AZFc+AZFd regions,accounting for 12.5%(1/8);1 patient was found with microdeletion of AZFa+AZFb+AZFc regions,accounting for 12.5%(1/8).The men in control group had normal chromosomal karyotype and had no microdeletion of AZF gene.There was significant difference in the microdeletion rate of AZF region in Y chromosome between experimental group and control group(P0.05).Conclusion:Male chromosomal abnormality and microdeletion of AZF region in Y chromosome are related to male azoospermia and oligozoospermia closely.
[Value of the early determination of plasma myoglobin level in the diagnosis of acute myocardial infarction]. (1994)

Serum myoglobin (Mb) was assayed by immuno-nephelemetry or immuno-turbidimetry together with creatinine kinase activity (CK) by spectrophotometry in 290 consecutive patients admitted to hospital between January 1st and September 30th 1992 in three cardiology departments for chest pain suggesting myocardial infarction (MI). The measurements were made at admission (T0) and 90 minutes later (T90). On admission, patients were classified as certain MI (N = 62), possible MI (N = 107) or definitely not MI (N = 121) and, on discharge, as certain MI (N = 144) or definitely not MI (N = 146). At T0, for a threshold value of 90 mcg/l, Mb assay had a sensitivity of 49.3% and a specificity of 95.2%, a positive predictive value of 91.8% and a negative predictive value of 65.6%. Increasing the threshold of positivity to 130 mcg/l was accompanied by a significant loss of sensitivity (38.2%) without any change in the other parameters. At T90, for a threshold value of 90 mcg/l, Mb assay had a sensitivity of 81.7%, a specificity of 92%, a positive predictive value of 89.5% and a negative predictive value of 85.8%. The increase in sensitivity between T0 and T90 made Mb assay very useful for correctly classifying the initial false negative results (20/28: 71.4%) and for diagnosing the possible MI (27/32: 84.4%). Decreasing the threshold of positivity to 80 or even to 70 mcg/l did not improve the diagnostic value of this test. The sensitivity of Mb assay was significantly higher than that of CK at T0 (49.3% vs 26.4%: p < 0.0001) and at T90 (81.7% vs 48.9%: p < 0.0001).(ABSTRACT TRUNCATED AT 250 WORDS)
The Name Lahndi (1930)

In the last number of the Bulletin Sir George Grierson has written a useful article on the regular, method of forming linguistic names in Indian languages. I agree with most, but not all, of it: thus the sentence “it is he who writes Lahndī for Lahndā, the latter having been undisputed for over forty years”, contains, it seems to me, five mis-statements of fact. They do not however affect the position. It is always interesting to reflect on what one would expect words to be and to compare that with what they actually are. English, Urdu, Panjabi, and Hindi swarm with words which have rejected the line of regular development and adopted another. People's attitude to such words varies with their temperament. Some describe them as “ atrocious examples of hybridism ” or “ false analogies ’ or more briefly as ‘ impossible ’. Similarly many writers call changed words ‘ corruptions ’. Others on the other hand find that in linguistic atters what is is much more interesting than what was , and still more so than what should be .
A Unified Approach to Minimum Risk Training and Decoding (2010)

We present a unified approach to performing minimum risk training and minimum Bayes risk (MBR) decoding with BLEU in a phrase-based model. Key to our approach is the use of a Gibbs sampler that allows us to explore the entire probability distribution and maintain a strict probabilistic formulation across the pipeline. We also describe a new sampling algorithm called corpus sampling which allows us at training time to use BLEU instead of an approximation thereof. Our approach is theoretically sound and gives better (up to +0.6%BLEU) and more stable results than the standard MERT optimization algorithm. By comparing our approach to lattice MBR, we are also able to gain crucial insights about both methods. 1
Rotordynamics analysis for the HPFTP (High Pressure Fuel Turbopump) of the SSME (Space Shuttle Main Engine). SSME turbopump technology improvements via transient rotordynamics analysis (1980)

The results of both linear (stability and synchronous response) and transient nonlinear analyses are reported. Dynamic coefficients were developed for the HPFTP interstage seals, and introduced into the rotordynamic model. The influence on HPFTP rotordynamics of a change in interstage seals from the smooth stepped design to a smooth straight configuration was examined. The sensitivity of the stability and synchronous results to changes in bearing stiffnesses and damping was determined. The influence on rotordynamic stability of a change from the stiff symmetric bearing carrier design to an asymmetric bearing carrier configuration was also studied.
Programmed cell death in heterokaryons. A study of the transfer of apoptosis between nuclei. (1992)

Thymocytes undergoing apoptosis induced by dexamethasone showed nuclear refractivity changes under Nomarski optics that correlated precisely with internucleosomal DNA degradation and was prevented by cycloheximide. When heterokaryons between thymocytes and 9L or NIH3T3 cells were examined, 99.75% of the nuclei in heterokaryons followed the original and distinct fate characteristic of the parental cells. Thymocyte nuclei proceeded to undergo apoptotic cell death, whereas the 9L and NIH3T3 nuclei in the heterokaryons did not show the morphologic changes of apoptosis or any DNA cleavage on gels, and remained viable and mitotic. Cycloheximide prevented the induction of apoptosis in thymocyte nuclei in the heterokaryons. An excess of up to seven thymocyte nuclei undergoing programmed cell death in a heterokaryon did not detectably damage the 9L nucleus, and an excess of six 9L nuclei did not protect the thymocyte nucleus from apoptosis. The proposed model stating that programmed cell death results from de novo synthesis of death-causing gene products is difficult to reconcile with these findings. A cell-type-specific activity, present in thymocyte nuclei before induction of apoptosis with corticosteroids and unable to diffuse between nuclei, appears to be responsible for DNA fragmentation. These results also show that nuclear disintegration is the trigger of thymocyte death and not a consequence of cell death due to another mechanism.
Ambulante Adipositastherapie unter partieller Anwendung einer Formuladiät verbessert Gewichtsstatus und Parameter des metabolischen Syndroms bei extrem übergewichtigen Jugendlichen (2003)

Effects of a Protein Optimized Diet Combined with Moderate Resistance Training on the Postoperative Course in Older Patients with Hip Fracture
The Evaluation of the PCB's Behaviour under the Mechanical Stress (2007)

The aspect of the vulnerability of electronics generated by the mechanical causes requires a special analyzing and testing effort of the packages in the context of each different particular application. The main goal of this paper is to present the numerical evaluation by finite element analysis of the common class of PCBs under the mechanical stress. This work contributes to the study of packaged electronics vulnerability by comparing the numerical results with experimental tests.
Stratigraphic modelling of platform architecture and carbonate production: a Messinian case study (Sorbas Basin, <scp>SE</scp> Spain) (2015)

Abstract The late Messinian mixed carbonate‐siliciclastic platforms of the Sorbas Basin, known as the Terminal Carbonate Complex, record significant changes in carbonate production and geometry. Their facies and stratigraphic architecture result from complex interactions between base‐level fluctuations, evaporite deformation/dissolution and detrital inputs. A 3D quantitative approach (with DIONISOS software) is used to explore the basin‐scale platform architecture and to quantify the carbonate production of the Terminal Carbonate Complex. The modelling strategy consists in integrating detailed 2D field‐based transects and modern carbonate system parameters (e.g. carbonate production rates, bathymetric and hydrodynamic ranges of production). This approach limits user impact and so provides more objective output results. Tests are carried out on carbonate production rates, subsidence and evaporite deformation/dissolution. Numerical modelling provides accurate predictions of geometries, facies distributions and depositional sequence thicknesses, validated by field data. Comparative statistical testing of the field transects and of the various model outputs are used to discern the relative contribution of the parameters tested to the evolution of basin filling. The 3D visualization and quantification of the main carbonate producers (ooids and microbialites) are discussed in terms of changes in base‐level and detrital supply. This study demonstrates that base‐level fluctuations have the greatest impact on the carbonate budget. Evaporite deformation/dissolution affects the type and amount of carbonate production, inducing a transition from an ooid‐ to microbialite‐dominated system and also has a major effect on stratigraphic architecture by inducing the migration of depocentres. The numerical modelling results obtained using modern carbonate system parameters could also be applied to subsurface ooid‐microbialite reservoirs, and the Terminal Carbonate Complex is a good analogue for such systems.
ChemInform Abstract: DIE REAKTIONEN VON OMEGA‐JODALKINEN MIT NICKELTETRACARBONYL‐KALIUM‐TERT.‐BUTYLAT (1973)

Abstract Die Jodalkine (I) reagieren mit dem Komplex aus Nickeltetracarbonyl (II) und Kalium‐tert‐butylat (III) in tert.‐Butanol bei Raumtemperatur zu geradkettigen und cyclischen Estern: Bei den Alkinen (I) mit n = 3 oder 5 über′= wiegen als Reaktionsprodukte die geradkettigen Verbindungen (IV), während bei n = 4 die cyclischen Verbindungen (V) und (VI) gebildet werden.
The free-powder magnetization of ferrimagnetic rare-earth transition-metal compounds (1993)

Magnetization curves have been calculated for single crystals of ferrimagnetic rare-earth transition-metal compounds that are free to rotate in the applied magnetic field. The calculations have been performed taking into account the magnetic-anisotropy constants of the rare-earth and transition-metal sublattices up to the fourth order. Seven different types of rotation processes can be distinguished.
Synthesis of WC/Co/Diamond Nanocomposites (1997)

ABSTRACT A new method had been developed for the synthesis of a triphasic WC/Co/diamond nanocomposite, comprising a high volume fraction of diamond in a WC/Co matrix. Starting with available nanophase WC/Co powder, the new process involves: (1) partial sintering of a WC/Co powder compact to develop a porous preform, (2) chemical vapor infiltration (CVI) of the porous preform with amorphous or graphitic carbon, and (3) high pressure/high temperature (HPHT) consolidation of the carbon-infiltrated WC/Co preform to develop a fully-dense WC/Co/diamond nanocomposite. In the critical CVI step of the process, the kinetics of the carbon deposition may be controlled to develop either an uniform or graded distribution throughout the porous WC/Co preform. A functionally-graded triphasic superhard material, comprising a nanophase WC/Co core and a diamond-enriched surface, should combine high strength and toughness with superior wear resistance.
The Synthesis of 9,10‐Dihydro‐9,10‐(methaniminomethano)anthracene and N‐Protected Derivatives via Double Reductive Amination. (2005)

Abstract For Abstract see ChemInform Abstract in Full Text.
ANALYSIS OF CASUALTIES REFERRED TO ARMY PHYSICAL MEDICINE SERVICES DURING THE PERSIAN GULF CONFLICT (1993)

This study describes the casualties referred during the Persian Gulf War and underscores the valuable role of Army physical medicine and rehabilitation (PMR) services in evaluation and early rehabilitation of wartime casualties. Data regarding demographics, injury types, medical complications, complications of immobility and functional limitations were collected by military physiatrists at five Army Medical Centers with PMR services. Active duty soldiers injured in the Persian Gulf War who were referred totalled 222. Musculoskeletal injuries occurred in 57%, peripheral nerve injuries in 44%, penetrating wounds in 32%, fractures in 28%, brain injuries in 8%, amputations in 7%, burns in 6% and spinal cord injuries in 3%. The primary referral service was orthopedics (64%). Electrodiagnosis evaluations were performed for 41% of all referrals. Lower limb and upper limb contractures occurred in 10% and 9% of patients, respectively. Ambulatory impairments were seen in 48%. Nerve injuries were associated with penetrating wounds in 68%, with amputations in 67% and with fractures in 58%.
Correction: Bijels stabilized using rod-like particles (2015)

Correction for 'Bijels stabilized using rod-like particles' by Niek Hijnen et al., Soft Matter, 2015, DOI: .
Thermodynamics of triple helix formation: spectrophotometric studies on the d(A)<sub>10</sub>·2d(T)<sub>10</sub>and d(C<sup>+</sup><sub>3</sub>T<sub>3</sub>C<sup>+</sup><sub>3</sub>)·d(G<sub>3</sub>A<sub>4</sub>G<sub>3</sub>)·d(C<sub>3</sub>T<sub>4</sub>C<sub>3</sub>) triple helices (1990)

We have stabilized the d(A)10.2d(T)10 and d(C+LT4C+3).d(G3A4G3).d(C3T4C3) triple helices with either NaCl or MgCl2 at pH 5.5. UV mixing curves demonstrate a 1:2 stoichiometry of purine to pyrimidine strands under the appropriate conditions of pH and ionic strength. Circular dichroic titrations suggest a possible sequence-independent spectral signature for triplex formation. Thermal denaturation profiles indicate the initial loss of the third strand followed by dissociation of the underlying duplex with increasing temperature. Depending on the base sequence and ionic conditions, the binding affinity of the third strand for the duplex at 25 degrees C is two to five orders of magnitude lower than that of the two strands forming the duplex. Thermodynamic parameters for triplex formation were determined for both sequences in the presence of 50 mM MgCl2 and/or 2.0 M NaCl. Hoogsteen base pairs are 0.22-0.64 kcal/mole less stable than Watson-Crick base pairs, depending on ionic conditions and base composition. C+.G and T.A Hoogsteen base pairs appear to have similar stability in the presence of Mg2+ ions at low pH.
High resolution electron spin resonance of organic free radicals (1964)

The amount of information on the structure of a free radical and on the extension of the orbital of the unpaired electron obtainable with electron-spin resonance (ESR) depends on the resolution of the spectrum. Since it is in principle always possible to fullfill the technical requirements for optimum resolution, the linewidth depends on the physical phenomena in the sample itself, i.e. the relaxation.
Mapping of Epitopes on Porcine Zona Pellucida-3α by Monoclonal Antibodies Inhibiting Oocyte-Sperm Interaction1 (1996)

Zona pellucida glycoprotein 3 alpha (ZP3 alpha) has been designated as the primary sperm receptor ligand in porcine gamete interaction. In this study, epitopes were mapped on porcine ZP3 alpha (pZP3 alpha) by using monoclonal antibodies (mAbs) possessing in vitro contraceptive efficacy. Using Western blots, we tested recombinant pZP3 alpha fragments expressed as fusion proteins in Escherichia coli and corresponding to pZP3 alpha precursor protein amino acid residues 18-142 (F1), 140-243 (F2), 239-363 (F3), and 359-462 (F4), for reactivities with mAbs. MAb-403 reacted with F3, and mAbs-412 and -421 with F2. MAb-420 showed weak reactivity with F1. Synthesis of overlapping 12-mer peptides further resolved the epitope for mAb-420 to amino acid residues 133-144, mAb-421 to 157-168, mAb-412 to 205-216, and mAb-403 to 301-312. MAbs-412 and -420 inhibited the binding of boar sperm to zona-encased porcine oocytes. These results, the first to define peptide epitopes of pZP3 alpha, should assist in the design of a synthetic peptide-based immunocontraceptive vaccine.
Design of a set of probes with high potential for influenza virus epidemiological surveillance (2013)

An Influenza Probe Set (IPS) consisting in 1,249 9-mer probes for genomic fingerprinting of closely and distantly related Influenza Virus strains was designed and tested in silico. The IPS was derived from alignments of Influenza genomes. The RNA segments of 5,133 influenza strains having diverse degree of relatedness were concatenated and aligned. After alignment, 9-mer sites having high Shannon entropy were searched. Additional criteria such as: G+C content between 35 to 65%, absence of dimer or trimer consecutive repeats, a minimum of 2 differences between 9mers and selecting only sequences with Tm values between 34.5 and 36.5oC were applied for selecting probes with high sequential entropy. Virtual Hybridization was used to predict Genomic Fingerprints to assess the capability of the IPS to discriminate between influenza and related strains. Distance scores between pairs of Influenza Genomic Fingerprints were calculated, and used for estimating Taxonomic Trees. Visual examination of both Genomic Fingerprints and Taxonomic Trees suggest that the IPS is able to discriminate between distant and closely related Influenza strains. It is proposed that the IPS can be used to investigate, by virtual or experimental hybridization, any new, and potentially virulent, strain.
Antibiotics GE23077, Novel Inhibitors of Bacterial RNA Polymerase. Part 2. Structure Elucidation. (2005)

Abstract For Abstract see ChemInform Abstract in Full Text.
Use of Monoclonal Antibodies for Studies of Anti-Ia Receptor Idiotypes (1983)

The Ia antigens form a highly polymorphic system of multideterminant glycoproteins, and most animals express products of more than one locus. As a result, serological analysis of these antigens has been quite complex. The recent availability of monoclonal antibodies (mAbs) provides a powerful tool for the analysis of the Ia system, and has decisive advantages for certain applications. For example, mAbs have made possible the definition of several steric domains on Ia molecules (1), and have allowed the separation of multiple gene products by sequential immuno- precipitation, helping to dissect the fine structure of the I region (2,3,4).
Effects of Sc content on the mechanical properties of Al‐Sc alloys (2010)

Abstract The effects of Sc content on the mechanical properties of Al‐Sc alloys were investigated. The results show that the strengths of all the tested alloys with 0.1 wt.%, 0.3 wt.%, and 0.4 wt.% Sc additions increase initially with an increase in annealing time, due to the increase in volume fraction and size and the decrease in particle interspacing of Al 3 Sc particles. After reaching peak values, the strengths of all the tested alloys start to decrease with increasing annealing time due to the coarsening and increase in particle interspacing of Al 3 Sc particles. It has also been shown that the alloy with 0.3 wt.% Sc has a higher strength and a lower elongation than the alloys with 0.1 wt.% and 0.4 wt.% Sc. The increase in strength and the decrease in elongation of the alloy with 0.3 wt.% Sc are due to the smaller particle interspacing of Al 3 Sc particles, resulting in a strong inhibition of dislocation movement during deformation.
Wide Band mm- and Sub-mm-Wave Dielectric Rod Waveguide Antenna (2014)

The design of a dielectric rod waveguide (DRW) antenna for frequencies of 75-325 GHz is presented. The optimal broadband antenna geometry is determined using numerical simulations . A single DRW antenna is matched with metal waveguides of different sizes for different frequency bands. Measurement results agree very well with the simulation results up to 325 GHz; the gain of the antenna stays nearly constant ( G ≈ 10 dB) over the whole frequency range measured from 75 to 325 GHz (160% relative bandwidth). The upper limit is due to our limited manufacturing capability to produce sharp antenna tips. The return loss of the antenna is better than 15 dB. The radiation patterns are nearly independent of frequency. The 3 dB beamwidth is 50 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">°</sup> -60 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">°</sup> , and the 10 dB beamwidth is about 95 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">°</sup> . This indicates that the aperture size of this end-fire antenna decreases as a function of frequency, and this observation agrees well with the earlier observation that the phase center of a DRW antenna moves towards the antenna tip as a function of frequency. Also the cross polarization was studied. The cross-polarization level is better than -15 dB at all frequencies .
Pharmacological Evaluation of Artemisia cina Crude CO2 Subcritical Extract after the Removal of Santonin by Means of High Speed Countercurrent Chromatography (2020)

<i>Artemisia</i> species are highly important due to their economic significance as medicines, fodder and food. <i>Artemisia cina</i> is an endemic species to Kazakhstan. In folk medicine, water extract of <i>A. cina</i> was used in the treatment of bronchial asthma while the alcohol extract has larvicidal and antituberculosis activity. The most common and most extensively studied compound from this species is the terpenoid santonin. The toxicity of this compound occurs at the doses of 60 mg for children and 200 mg for adults causing among other issues xanthopsia, leading to blindness. Having this in mind, the main idea of this work was to remove santonin from the crude extract and to check if the santonin-free extract would still be of any pharmacological importance. A CO<sub>2</sub> subcritical extract was chromatographed using high-speed countercurrent chromatography (HSCCC) for the removal of santonin. The santonin-free CO<sub>2</sub> subcritical extract (SFCO<sub>2</sub>E) as well as the isolated compound pectolinarigenin, a flavonoid, were assessed for their pharmacological actions. From the results obtained we can safely suggest that HSCCC is an efficient methodology to completely remove santonin from the CO<sub>2</sub> subcritical extract. It was also possible to observe promising antinociceptive and anti-inflammatory activities for both SFCO<sub>2</sub>E and pectolinarigenin at concentrations that can justify the production of a phytomedicine with this endemic plant from Kazakhstan.
Exchange of information: The French Competition Council imposes fines for practices of price fixing and exchange of information on prices (eau de javel) (2005)

Amendes pour accord de fixation et echanges de prix Cons. conc., dec. n° 05-D-03 du 10 fevrier 2005 relative a des pratiques mises en œuvre dans le secteur de l'eau de javel Confrontes a une erosion…