gebhart/patrepeval huggingface dataset:
SPECTROSCOPIC ANALYSIS OF CARCINOGENIC HYDROCARBONS IN BIOLOGIC INTERACTION IN VIVO AND IN VITRO. (1963)

In vivo fluorescence spectroscopy of the rabbit ear chamber after implantation of benzpyrene revealed various carcinogen-tissue complexes. Immediately after implantation a uniform spectrum was invariably obtained anywhere in the chamber, and its form suggests an initial solution of the carcinogen similar to that produced in serum. In the period 1–22 days postimplantation, emission spectra were obtained similar to metabolites isolated through in vitro procedures reported in the literature. The emission spectra appeared to originate intracellularly.

The intensity of fluorescence was greatest shortly after implantation and decreased as a function of time. The emission at the longer wavelengths became dominant as time progressed or as tissue was examined further away from lodged particles in the ear chamber.

Methylcholanthrene in the chamber and dibenzanthracene in the lung underwent spectral alteration much more slowly than did benzpyrene in the respective sites of implantation.

In vitro experiments with carcinogen and ascites cells revealed spectra similar to those produced early after implantation in the ear chamber.

Fluorescence emission spectra of 3,4-benzpyrene in polar and nonpolar solvents and in serum are similar. Rate of solution of benzpyrene in serum was characterized by different slopes for each emission maximum. Thus, although a common molecular phenomenon represented by these peaks occurred at solution, either three molecular species were present or one species with three transitions.

The spectrally demonstrable serum interactions of the various hydrocarbons studied were not specific for the carcinogenic ones.
Photoluminescence investigation of phononless radiative recombination and thermal-stability of germanium hut clusters on silicon(001) (2001)

Intense photoluminescence (PL) originating from single layers of germanium hut clusters grown on silicon (001) is investigated using PL spectroscopy. We propose that the luminescence originates from phononless recombination within a spatially indirect, type-II neighboring confinement structure. Enhanced no-phonon (NP) luminescence is attributed to exciton localization at the Ge/Si interfaces. The PL intensity is sensitive to the growth temperature during interface formation, as well as to post-growth thermal annealing, illustrating the influence of atomic-level Si–Ge intermixing on exciton localization and NP enhancement.
Parachordoma of tibia--a case report. (2003)

A rare case of a 24-year old male patient with 'parachordoma' of left tibia having the characteristic histopathological and histochemical features of chordoma occurring in an unconventional site, which was clinically and radiologically diagnosed as osteoclastoma is presented here. The case is presented considering the extreme rarity of the lesion in literature in long bones.
Trajectory displacement effect in particle projection lithography systems: Modifications to the extended two-particle theory and Monte Carlo simulation technique (1998)

The extended two-particle model for statistical interactions in particle beams, developed by Jansen [Coulomb Interactions in Particle Beams (Academic, Boston, 1990)], has been refined to improve the accuracy of the predictions of the trajectory displacement effect in particle beam projection systems. The original theory was developed for probe forming systems, such as electron and ion scanning microscopes and Gaussian or shaped beam lithography systems. Fit functions are used within the theory to express part of the numerical output into explicit analytical prescriptions. These functions were found to become inaccurate for the relatively wide beams typically used in the more recently developed projection type lithography systems. New fit functions are presented which extend the applicability of the theory to the wide beams and doublet configurations used in projection systems. The Monte Carlo program MONTEC, used to verify the results of the analytical theory, has been modified as well to account for the first order space charge magnification effect. This effect could be ignored for the relatively small spots of Gaussian and shaped beam systems, but would yield a significant overestimation of the trajectory displacement effect—assumed to be identical to the remaining blur after refocusing—for the wide images used in projection type of systems. The refined analytical theory and the modified MONTEC program have been used to evaluate the impact of statistical interactions on the performance of the SCALPEL electron projection system and a hypothetical ion projection lithography system, representing a simplified model of the IMS ALG-1000 (He+) system. The analytical predictions are in good agreement with the Monte Carlo results. An estimate of the total system resolution, determined by the combined effect of statistical interactions and geometrical aberrations, indicates that maximum attainable beam current for a 0.18 μm design rule is about 25 μA for the SCALPEL and 0.2–0.3 μA for the ion projection system, leading to an ∼10× higher throughput for the former taking the difference in resist sensitivities for electrons and ions into account.
Facile chemical synthesis and enhanced thermoelectric properties of Ag doped SnSe nanocrystals (2017)

A two-step, surfactant-free solution growth process was utilized to synthesize p-type Ag doped SnSe nanocrystals in gram quantities.
Love wave chemical sensors: design and optimisation. Case of organophosphorous compounds detection (2004)

Love wave sensors are now a relatively well known surface acoustic wave sensors type. They have many advantages on the other acoustic waves sensors, (mainly Rayleigh mode and bulk acoustic modes); among them we can notice two specials: better sensitivity and ability to operate in liquid medium. To maximize a sensor sensitivity, each of its components must be designed on this purpose. The chemical layer main characteristic is to have a good affinity versus the compound to detect. This considerably reduces the choice for sensitive material, thus the optimisation process concerns mainly the other parts of the structure. In this paper we focus on a three layered Love wave sensor platform optimisation to have a maximum sensitivity for a given sensitive layer studied for the detection of organophosphorous compounds. We start by explaining how the simulator is build: the kernel physical model equations, and the computing interface needed to extract information from the simulator kernel. Then we show the simulation results which led to final sensor design. Finally we conclude on the application field of such a simulation tool: it can be used for structure optimisation, material characterisation, and a deeper propagation phenomenon understanding.
The preparation of human articular cartilage for scanning electron microscopy (1976)

This paper compares sixteen preparative techniques thought to be of advantage in the study by scanning electron microscopy (SEM) of human articular cartilage surfaces. The adequacy of surface preservation obtained with the techniques, was judged subjectively, first, by the reproducubility of secondary electron images of normal cartilage, and second, by comparing the results with those obtained by reflected light microscopy of the fresh unfixed cartilage surface over a magnification range of X20- X240. Adequate surface preservation was confirmed when cartilage surfaces had been dehydrated through ethanol to propylene oxide and vacuum dried; dehydrated through amyl acetate and quenched in Freon before freeze-drying; dehydrated and passed through amyl acetate at low temperature before freeze drying. Valuable information can be obtained from different specimens by varying the technique of preparation. At different ages, different surface features are best preserved. In a systematic study it has been found essential to adopt a uniform preparative method and to control the results by reflected light microscopy. Even with the most perfect preparation, the surface appearances cannot be identical with those that function under load in vivo.
Magnetic Properties and Defects in Iron Implanted Strontium Titanate Single Crystals and Thin films (2012)

Physical vapor deposition was used to grow good quality crystalline stoichiometric SrTiO3 thin films on Si(001) substrate using a systematic approach starting from understanding of kinetics and thermodynamics of the system and finishing with the development of procedure for high quality SrTiO3/Si interface. Growth of optimized SrTiO3 perovskite structure on Si requires careful transformation of a thin interfacial SrSix layer into the initial SrTiO3 lattice cells. The critical aspects of the growth, such as low temperature and low oxidant partial pressure, are explained in details. Crystallinity and stoichiometry of SrTiO3 were verified using powder x-ray diffraction (XRD) and Rutherford backscattering spectroscopy (RBS). SrTiO3/Si(001) interface was examined with X-ray photoemission spectroscopy (XPS) and RBS and optimum composition can be represented with low concentration (thickness) of strontium silicate phases at the interface (SrxSiyOy) as well as strong signal from strontium titanate peaks. Thicker samples were grown with the developed procedure and were implanted with iron at 2´1016 ions/cm2 for future magnetic characterization.\nIn parallel to the thin film growth, (001) SrTiO3 single crystals were implanted with iron at doses ranging from 2x1014 to 2x1016 ions/cm2 ­and their magnetic measurements were carried out with superconducting quantum interference device (SQUID). The results show negative susceptibility, predominately diamagnetic behavior which is characteristic of SrTiO3 and small paramagnetic response at low magnetic fields, indicating the possible presence of oxygen/titanium vacancies. Temperature dependence of magnetization measurements did not reveal phase changes. We note that it was difficult to identify any trends between implanted samples most likely due to oxygen contamination of the measurement system. Future experiments are proposed to develop a quantitative and consistent agreement between Fe phases in SrTiO3, SrTiO3 defect concentrations and magnetic responses.
Quantitative Risk Analysis: A Guide to Monte Carlo Simulation Modelling (1996)

Introduction to Monte Carlo Simulation Modelling Probability and Statistics Theory Review A Guide to Probability Distributions Building a Risk Analysis Model Determining Input Distributions from Expert Opinion Determining Input Distributions from Available Data Modelling Dependencies Between Distributions Project Risk Analysis Adding Uncertainty to Forecasts Presenting and Interpreting Risk Analysis Results A Selection of Worked Problems.
Research of Key Technologies for Blue GaN-Based LEDs (2008)

Semiconductor lighting technology on high brightness blue GaN-based LEDs impacts illumination field largely,and it has been focus in the semiconductor research and investment at present.This paper was overviewed the basic properties of GaN-based material,analyzed key technologies in making blue GaN-based LEDs,such as MOVPE,P-doping ohmic contact,etching and chip dicing saw,and introduced recent progresses of technologies at present.At last,pointed out problems that we must prospect,and also discussed the future trend.
Requirement of VPS33B, a member of the Sec1/Munc18 protein family, in megakaryocyte and platelet  -granule biogenesis (2005)

Bleeding problems are associated with defects in platelet alpha-granules, yet little is known about how these granules are formed and released. Mutations affecting VPS33B, a novel Sec1/Munc18 protein, have recently been linked to arthrogryposis, renal dysfunction, and cholestasis (ARC) syndrome. We have characterized platelets from patients with ARC syndrome and observed reduced aggregation with arachidonate and adenosine diphosphate (ADP). Structural abnormalities seen in ARC platelets included increased platelet size, a pale appearance in blood films, elevated numbers of delta-granules, and completely absent alpha-granules. Soluble and membrane-bound alpha-granule proteins were significantly decreased or undetectable in ARC platelets, suggesting that both the releasable protein pools and membrane components of alpha-granules were absent. The role of VPS33B in platelet granule biogenesis was evaluated by immunofluorescence microscopy in normal human megakaryocytes. VPS33B colocalized appreciably with markers of alpha-granules, moderately with late endosomes/lysosomes, minimally with delta-granules/lysosomes, and not with cis-Golgi complexes. VPS33B protein expression determined by immunoblotting confirmed the presence of VPS33B in control fibroblasts but not in ARC fibroblasts, and in normal megakaryocytes but not in platelets. We conclude that like other Sec1/Munc18 proteins, VPS33B is involved in intracellular vesicle trafficking, being essential for the development of platelet alpha-granules but not for granule secretion.
Design Intent Information Exchange of Feature-Based CAD Models (2009)

Modern feature-based CAD system can represent design intent with construction history, feature, parameterization and constraints. Until recently, standards for CAD data exchange among different CAD system were restrict to the exchange of pure geometrical information. This paper discusses the contents, formalization and characteristics of design intent of feature-based CAD models and the information exchange mode in detail. The problems of representing and exchanging the information of design intent are also discussed. An approach to mapping design intent information among CAD system is presented. According to the newly published parts of the International Standard ISO 10303, A XML neutral format of information exchange model is presented.
Randomized phase II clinical trial comparing tremelimumab (CP-675,206) with best supportive care (BSC) following first-line platinum-based therapy in patients (pts) with advanced non-small cell lung cancer (NSCLC) (2009)

8071 Background: Pts diagnosed with advanced NSCLC with good performance status typically receive platinum-based chemotherapy; however, no approved maintenance therapy exists. Tremelimumab, a fully human anti-CTLA4 mAb, is associated with durable responses in some pts with metastatic melanoma. Methods: This open-label, randomized, multicenter, phase II clinical trial evaluating efficacy and safety of tremelimumab as maintenance therapy was conducted in pts with locally advanced or metastatic NSCLC with ECOG performance status ≤1. Pts treated with ≥4 cycles of first-line platinum-based therapy resulting in either stable disease (SD) or response per RECIST were eligible and were randomized 3–6 weeks after prior therapy. Pts received 15 mg/kg IV tremelimumab Q90D or BSC until disease progression. Primary endpoint was progression-free survival (PFS) at 3 months. Secondary endpoints included safety, objective response rate, and 1-year survival. Results: Eighty-seven pts received tremelimumab (n=44) or BSC (n=43). Nine (20.9%; 90% CI: 11.4%, 33.7%) pts receiving tremelimumab and 6 (14.3%; 90% CI: 6.4%, 26.3%) pts receiving BSC were progression free at 3 months. Among pts receiving tremelimumab, there were 2 (4.8%) partial responses and 7 (16.6%) SDs, compared with 0 and 6 (14.3%) pts receiving BSC, respectively. Treatment-related adverse events (AEs) were observed in 27 (61.4%) pts receiving tremelimumab and 3 (7.0%) receiving BSC. Nine pts (20.5%) receiving tremelimumab reported grade 3 or 4 AEs compared with 0 patients receiving BSC. The most common grade 3 or 4 AEs attributed to tremelimumab were diarrhea and colitis (n=4, 9.1%). Conclusions: In pts with advanced NSCLC and good performance status receiving platinum-based first-line therapy, single-agent tremelimumab was tolerable, with safety consistent with prior studies. Although PFS analysis did not demonstrate superiority of tremelimumab over BSC, the 4.8% objective response rate seen only in the investigational arm may support future combination studies. Analysis of 1-year survival is forthcoming. [Table: see text]
Low-density carbonized composite foams for direct-drive laser ICF targets (1989)

The design for a direct-drive, high-gain laser inertial confinement fusion target calls for the use of a low-density, low-atomic-number foam to confine and stabilize liquid deuterium-tritium (DT) in a spherical-shell configuration. Over the past two years, we have successfully developed polystyrene foams (PS) and carbonized resorcinol-formaldehyde foams (CRF) for that purpose. Both candidates are promising materials with unique characteristics. PS has superior mechanical strength and machinability, but its relatively large thermal contraction is a significant disadvantage. CRF has outstanding wettability and dimensional stability in liquid DT; yet it is much more fragile than PS. To combine the strengths of both materials, we have recently developed a polymer composite foam which exceeds PS in mechanical strength, but retains the wettability and dimension stability of CRF. This paper will discuss the preparation, structure, and properties of the polymer composite foams. 5 refs., 1 fig., 1 tab.
Petroleum Pipe Leakage Detection and Location Embeded in SCADA (2004)

With the increase of the age of the transport oil pipeline and the man-made destruction to pipeline, leaks are often found. The system for pipeline leakage detection and location must be established to find leakage and locate the leak positions to reduce serious environmental pollution and economic loss caused by leakage. The negative pressure wave method is an effective way to locate the leak position, because over 98 percent pipe leakage in China is paroxysmal. There is a SCADA (supervisory control and data acquisition) system to monitor operation for long transport petroleum pipe, but the function of leakage detection and location is not included in existing SCADA system in China. This paper used Dynamic Data Exchange (DDE) method to obtain pipe operation parameters such as pressure, flow rate, temperature, bump current, valve position and so on from the SCADA system. That takes full advantage of the abundant data collection function of the SCADA system to provide data for leakage detection and location. The wavelet packet analysis-based fault diagnosis method can directly use the change of parameters such as energy of frequency component to detect faults without system model. In the paper, a wavelet packet analysis-based characteristic extraction method is used to extract the characteristic information of leak pressure signals. The eigenvector indexes along with the parameters obtained from the SCADA system can be used to avoid false alarms. Wavelet analysis was used to locate leak positions accurately in this paper. Such a wavelet analysis-based leakage detection and location scheme embedded in the SCADA system has been successfully applied to a pipeline in PetroChina. Practical run demonstrated its well effect.
A single-precision compressive sensing signal reconstruction engine on FPGAs (2013)

Compressive sensing (CS) is a promising technology for the low-power and cost-effective data acquisition in wireless healthcare systems. However, its efficient realtime signal reconstruction is still challenging, and there is a clear demand for hardware acceleration. In this paper, we present the first single-precision floating-point CS reconstruction engine implemented a Kintex-7 FPGA using the orthogonal matching pursuit (OMP) algorithm. In order to achieve high performance with maximum hardware utilization, we propose a highly parallel architecture that shares the computing resources among different tasks of OMP by using configurable processing elements (PEs). By fully utilizing the FPGA recourses, our implementation has 128 PEs in parallel and operates at 53.7 MHz. In addition, it can support 2x larger problem size and 10x more sparse coefficients than prior work, which enables higher reconstruction accuracy by adding finer details to the recovered signal. Hardware results from the ECG reconstruction tests show the same level of accuracy as the double-precision C program. Compared to the execution time of a 2.27 GHz CPU, the FPGA reconstruction achieves an average speed-up of 41x.
Betriebswirtschaftliche Aspekte des Cash-Flow-Underwriting und einer rentabilitätsbezogenen Annahmepolitik bei Erstversicherern (1993)

ZusammenfassungIn der Systematik versicherungswirtschaftlicher Rechnungslegung wird unterschieden zwischen dem versicherungstechnischen und dem nicht-versicherungstechnischen Ergebnis. Das versicherungstechnische und das nicht-versicherungstechnische Ergebnis zusammengeführt ergeben das Gesamtergebnis des Versicherers.
RBANS Performance: Influences of Sex and Education (2003)

A sample of 278 men and 353 elderly women who resided in the community received the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) as part of a study of health in mature adult Oklahomans. Females attained significantly higher scores on the Immediate and Delayed Memory and the Language Indexes. Males performed better on the Visuospatial/Construction Index, but there was no sex difference on the Attention or Total Indexes. Differences related to sex were modest (2-6 Index points), but combined with the larger effects of education could lead to an adjustment of up to 11 Index points.
Seasonal Activity ofHelicoverpa zeaandHeliothis virescens(Lepidoptera: Noctuidae) Detected by Pheromone Traps in the Rolling Plains of Texas (1998)

Bollworm, Helicoverpa zea (Boddie), and tobacco budworm, Heliothis virescens (F.), male moth activity were monitored for 15 yr (1982–1996) in sex pheromone traps in the Rolling Plains of Texas. The study consisted of 2 types of survey as follows: (1) weekly monitoring of bollworm and tobacco budworm moths in Hardeman and Knox counties to investigate their long-term seasonal activity patterns, and (2) daily monitoring of bollworm moths in Haskell, Knox, and Wilbarger counties to quantify the effect of lunar cycles on moth generation cycles. Moths were active from early April to late October, with increasing activity as the growing season of cotton, Gossypium hirsutum L., progressed through September. Although the bollworm–budworm complex in the region consisted of ≈93% bollworms and only ≈7% tobacco budworms, the seasonal trends in activity patterns were similar for both species. Correlation analyses showed a significant positive relationship between weekly trap catch and temperatures, but a significant negative relationship was observed between trap catch and wind velocity for both species. Although the average monthly activity levels were positively correlated between adjacent months, there was no significant correlation between the activity of the moth population that contributed to the overwintering generation and the following spring population. Mean seasonal abundance curves, with upper confidence limits, were constructed for each species based on 15-yr averages. The mean abundance curves of this type are useful for identifying years with unusual moth severity. Daily trap catch data showed that the moon phase influenced the capture of bollworm moths in pheromone traps, as indicated by a significant positive correlation between trap catch and percentage moon illumination. Daily trap catch data also showed that the maximum trap catch occurred 71% of the time during the full moon, followed by 1st quarter (11%), last quarter (9%), and the new moon (9%). However, the relationship between the trap catch and the lunar cycles was not apparent when the traps were serviced weekly, indicating the importance of sampling frequency in detecting the relationship between trap catch and moon phase.