gebhart/patrepeval huggingface dataset:
Isolation and Characterization of Mutants Affected in Lipid Metabolism of <i>Chlamydomonas Reinhardtii</i> (1995)

Two mutants affected in lipid metabolism of Chlamydomonas reinhardtii were isolated by treating cells with ultraviolet light. Both mutants showed high chlorophyll fluorescent yields, as compared with parents, and were designated as hf-2 and hf-9 (for high fluorescence). hf-2 was shown to be defective in the synthesis of a chloroplast-specific lipid, sulfoquinovosyl diacylglycerol. hf-9 was shown to be defective in desaturation at the omega 6 position of fatty acids of monogalactosyl diacylglycerol, digalactosyl diacylglycerol, sulfoquinovosyl diacylglycerol and phosphatidylglycerol. The mutants exhibited alterations in photosynthetic activity and chloroplast ultrastructure.
Microstructural Evaluation of Welded Pearlitic Rail Steel (2013)

Extended abstract of a paper presented at Microscopy and Microanalysis 2013 in Indianapolis, Indiana, USA, August 4 – August 8, 2013.
Eaton, Horace, 1904 November 11 (1904)

paper copy; fragment, photocopy of first page sent from Michigan with a request for article. The complete letter photocopy will be requested asap. Tdk 08/10/01
Immunohystochemical analysis of SOCS3 in prostatic adenocarcinoma biopsies. (2011)

e15132 Background: Chronic inflammation and the subsequent tissutal alterations may play a key role in prostate carcinogenesis. Molecular alterations of the suppressor of cytokine signaling (SOCS)3, can contribute to explain the pleiotropic role of interleukin (IL)-6 in this type of cancer. In a recent study, we demonstrated that methylation of SOCS3 may be involved in the pathogenesis of prostate cancer and could identify in a subset of tumor with an aggressive behavior. Methods: We analyzed the protein expression of SOCS3 by immunohistochemistry in 50 prostate cancer biopsies: 30 prostatic carcinoma with Gleason score 7, 10 with Gleason score <7 and 10 with Gleason score >7. Slides were incubated with monoclonal antibody SOCS3 (1E4) (1.5 mg/ml; Abnova, Taiwan). The SOCS3 staining intensity were evaluated by two pathologist (FP and LML) in three different way: positive; negative; weak intensity staining with negative neoplastic glands. Colonic mucosa were used as positive control. Results: SOCS3 positive were found in all cases of adenocarcinoma Gleason score < 7 and in 10 cases with Gleason score 7, negative staining were found in all cases of adenocarcinoma Gleason score > 7 and in 8 cases with Gleason score 7. Weak SOCS3 staining with presence of negative neoplastic glands were found in 12 cases of adenocarcinoma Gleason score 7. The group of tumor SOCS3 negative were significantly more aggressive than group SOCS3 positive in terms of TNM stage,positivity of surgical margin. Cases with weak SOCS3 staining and negative neoplastic glands displayed more aggressive clinical behavior than cases SOCS3 positive (increase number of T3a and positive surgical margins), on the other hand unlike SOCS3 negative no stage T3b and lymphnode metastasis were found. Conclusions: Immunohystochemical analysis of SOCS3 protein unlike methylathion study identify three different groups of tumors: positive, negative and with weak SOCS3 staining with the presence of negative neoplastic glands. In this last group the reduction of expression protein and the presence of negative neoplastic glands could indicate an intermediate stage of tumor turning towards shutdown of SOCS3 and thus object of strict follow-up and suitable to demethylating agents therapy.
Stereochemical and mechanistic features of asymmetric Pauson–Khand processes (2000)

The absolute stereochemical configurations of a series of optically pure alkyne–Co2(CO)5PPh3 complexes and their corresponding cyclopentenones, derived from Pauson–Khand reaction with norbornene, have been established; an X-ray crystal structure of an optically pure cyclopentenone has facilitated this study. In turn, this has led to the unambiguous determination of the site of decarbonylation and alkene complexation when such monophosphine complexes are utilised in asymmetric Pauson–Khand processes.
Proximal colon distention increases Fos expression in the lumbosacral spinal cord and activates sacral parasympathetic NADPHd-positive neurons in rats (1998)

Fos expression induced by nociceptive mechanical distention of the proximal colon was examined in the lumbosacral spinal cord in freely moving rats equipped with a chronic balloon in the proximal colon. Fos protein in lumbosacral neurons was detected immunocytochemically, and colocalization with nicotinamide adenine dinucleotide phosphate diaphorase (NADPHd) activity was determined histochemically at 1 hour after distention. Distention of the proximal colon (10 ml, 30 seconds on/off for 10 minutes, about 90 mm Hg) increased the number of Fos-positive cells in the lumbar 6 (L6) and sacral 1 and 2 (S1, S2) segments, whereas no change was observed in the L1-L5 and S3 segments compared with the sham distended group or with animals that received no treatment. In L6-S2 segments, Fos-positive neurons were increased by two-fold in laminae I-VII (mainly in laminae I and outer II) and area X (surrounding the central canal) and by nine-fold in the sacral parasympathetic nucleus. Results of time course studies indicate that the maximal increase in Fos expression observed at 1 hour after distention returns to basal levels within 4 hours. In the S1 segment, distention of the proximal colon increased the percentage of NADPHd/Fos-positive neurons selectively in the parasympathetic nucleus by 40% compared with less than 4% in the sham distention group; the number and pattern of NADPHd-stained cells were not modified. These results indicate that noxious distention of the proximal colon for a short duration in awake rats selectively activates neurons in the L6-S2 segments of the dorsal horn mainly in laminae involved in nociceptive and autonomic processing. The marked activation of NADPHd-positive neurons in the sacral parasympathetic nucleus suggests a possible role of nitric oxide in the visceroautonomic reflexes induced by distention of the proximal colon.
Troglitazone‐induced intracellular oxidative stress in rat hepatoma cells: A flow cytometric assessment (2003)

Multiparameter flow cytometric evaluation of N1S1 cells indicated that the chromane ring of TRO, rather than the TZD moiety, may be responsible for oxidative stress and suggested that a direct effect on mitochondrial physiology may play a role in TRO-mediated hepatotoxicity.
A conscious scheme for remediation of odour nuisance at sewage treatment plants (2000)

A standard methodology is presented to remediate odour nuisance at sewage treatment plants. The basic procedure of this methodology is formed by a conscious scheme which integrates all relevant steps in the remediation process (investigative actions, migitating measures, communication, etc.). Theaim of this methodology is to obtain a realistic plan of action, keeping count with local boundary conditions (available resources, available knowledge, certainty about the causes, etc.). In this way, the methodology functions also as a backbone when a well defined odour regulation is lacking, as is the case in Flanders for the moment.
An atomic beam magnetic resonance apparatus for short-lived isotopes (1964)

An atomic beam magnetic resonance apparatus has been built to measure the spins and moments of radioactive nuclei, produced by neutron capture, having half lives t as short as approximately half a minute. It has been used to study 66Cu (t = 5.2 min) and 108Ag (t = 2.3 min), and could be applied to any isotope, with a half-life greater than 15 seconds, formed in a solid sample from an isotope with a sufficiently large abundance and slow neutron capture cross section.
EMI and microwave absorbing efficiency of polyaniline-functionalized reduced graphene oxide/γ-Fe<sub>2</sub>O<sub>3</sub>/epoxy nanocomposite (2020)

Polyaniline-decorated reduced graphene oxide/ferrite nanofiller (RGPF) prepared by the solution mixing method in three different ratios (1 : 3, 1 : 1 and 3 : 1) of polyaniline-decorated reduced graphene oxide and ferrite have been studied for microwave absorption properties in defence application. The polyaniline-decorated reduced graphene oxide/ferrite and neat ferrite nano-fillers have been used for the preparation of an epoxy nanocomposite (RGPFE) of 60 wt%. The distribution of the RGPF nanofiller in the epoxy matrix was analyzed by field emission scanning electron microscopy. Further, thermal gravimetric analyses revealed the excellent thermal stability of the nanocomposites. A vibrating sample magnetometer was employed to find out the magnetic behavior of the prepared nanocomposites. The complex permittivity and permeability were investigated to evaluate the principal properties in the frequency range from 2 to 18 GHz. These results show that an epoxy nanocomposite with 60 wt% RGPF filler in the ratio of 3 : 1 has maximum dielectric loss. Finally, these electromagnetic data were used to calculate the reflection loss of the epoxy nanocomposites, and showed good agreement between the calculated and measured data of these nanocomposites. The minimum reflection loss was observed as -10.26 dB in the X band with a thickness of 3.0 mm, and the bandwidth was 8.47 GHz for RL ≤-10 dB. On the basis of the above observations, these nanocomposites could be a good candidate for electromagnetic interference shielding (EMI) and microwave absorption applications.
Reflection correction for high accuracy transmittance measurements on filter glasses (1973)

Multiple reflections in the sample compartment of a spectrophotometer constitute a source of systematic bias in transmittance measurements on filter glasses. This bias may be removed by applying a numerical correction obtained from measurements on tilted samples in polarized light. For a high-accuracy spectrophotometer, this correction was found to be of the order of several 10<sup>-4</sup> transmittance units, independent of polarization, but slightly wavelength dependent.
Electrical impedance myography in facioscapulohumeral muscular dystrophy (2016)

EIM is a reliable measure of muscle composition in FSHD that offers the possibility to serially evaluate affected muscles. Muscle Nerve 54: 696-701, 2016.
Phosphoinositide 3-Kinase γ Inhibits Cardiac GSK-3 Independently of Akt (2013)

Activation of cardiac phosphoinositide 3-kinase α (PI3Kα) by growth factors, such as insulin, or activation of PI3Kγ downstream of heterotrimeric guanine nucleotide-binding protein (G protein)-coupled receptors stimulates the activity of the kinase Akt, which phosphorylates and inhibits glycogen synthase kinase-3 (GSK-3). We found that PI3Kγ inhibited GSK-3 independently of the insulin-PI3Kα-Akt axis. Although insulin treatment activated Akt in PI3Kγ knockout mice, phosphorylation of GSK-3 was decreased compared to control mice. GSK-3 is activated when dephosphorylated by the protein phosphatase 2A (PP2A), which is activated when methylated by the PP2A methyltransferase PPMT-1. PI3Kγ knockout mice showed increased activity of PPMT-1 and PP2A and enhanced nuclear export of the GSK-3 substrate NFATc3. GSK-3 inhibits cardiac hypertrophy, and the hearts of PI3Kγ knockout mice were smaller compared to those of wild-type mice. Cardiac overexpression of a catalytically inactive PI3Kγ (PI3Kγ(inact)) transgene in PI3Kγ knockout mice reduced the activities of PPMT-1 and PP2A and increased phosphorylation of GSK-3. Furthermore, PI3Kγ knockout mice expressing the PI3Kγ(inact) transgene had larger hearts than wild-type or PI3Kγ knockout mice. Our studies show that a kinase-independent function of PI3Kγ could directly inhibit GSK-3 function by preventing the PP2A-PPMT-1 interaction and that this inhibition of GSK-3 was independent of Akt.
T-ray sensing applications: review of global developments (2005)

Terahertz wavelengths can pass through dry, non-polar, non-metallic materials that are opaque at visible wavelengths. Moreover they can be manipulated using millimeter wave and quasi-optical techniques to form an image. Sensing in this band potentially provides advantages in a number of areas of interest for security and defense, such as screening of personnel for hidden objects, and the detection of chemical and biological agents. This paper reviews recent research into THz applications by groups across Europe, the US, Australasia, and the UK. Several private companies are developing smaller and cheaper reliable devices allowing for commercialisation of these applications. While there are a number of challenges to be overcome there is little doubt that THz technologies will play a major role in the near future for advancement of security, public health and defense.
Laparoscopic Roux-en-Y gastric bypass in super obese Göttingen minipigs. (2013)

The use of obese Göttingen minipigs as a translational RYGBP model is feasible and has potential for the study of RYGBP-related changes in gut function, type-2 diabetes and appetite regulation. Still, the surgical procedure is technically highly demanding in obese Göttingen minipigs and the peri-operative animal care and follow up requires close monitoring.
Highly detuned Rabi oscillations for a quantum dot in a microcavity (2013)

Pronounced Rabi oscillations at large detunings are predicted for a system consisting of a semiconductor quantum dot in a microcavity. Besides an anticrossing at zero detuning, two additional anticrossings are possible at microcavity detunings of one longitudinal-optical-phonon frequency below and above the quantum-dot resonance. These phonon-assisted Rabi oscillations generally exhibit complex spectral features. The investigation is performed with a quantum-electrodynamical model, where the phonon reservoir effects are treated beyond the customary Markov, second-order Born approximation.
Compressive sensing-based Preisach hysteresis model identification (2015)

The Preisach hysteresis model has been adopted extensively in the modeling of magnetic and smart material-based systems. Fidelity of the model hinges on accurate identification of the Preisach density function. Existing work on the identification of density function usually involves applying an input that contains sufficient excitation and measuring a large set of output data. In this paper, we propose a novel compressive sensing-based Preisach model identification approach that requires much fewer measurements. The density function is transformed into the frequency domain, generating a sparse signal of discrete cosine transform (DCT) coefficients, which can be efficiently reconstructed using compressive sensing algorithms. The root-mean-square error (RMSE) and the maximum absolute error are adopted to examine the density function reconstruction capability and the model estimation performance. The effectiveness of the proposed identification scheme is illustrated through both simulation results and experiments involving a vanadium dioxide (VO <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</inf> )-integrated microactuator.
[Cervical cancer in Bas-Rhin: trend and prediction of the incidence in 2014]. (2002)

The decrease of invasive tumors is due to screening. The improvement of the quality of the screening and treatment of in situ tumors would allow the number of incident cases of cervix cancer to decrease.
Phase 2 study of S‐1 and carboplatin plus bevacizumab followed by maintenance S‐1 and bevacizumab for chemotherapy‐naive patients with advanced nonsquamous non–small cell lung cancer (2013)

The regimen of combined S-1, carboplatin, and bevacizumab followed by maintenance with S-1 and bevacizumab was active and feasible as first-line treatment for advanced nonsquamous NSCLC.
Structural-Chemical Disorder of Manganese Dioxides: I- Influence on Surface Properties at Solid/Liquid Interface (2003)

Relationships between lattice parameters of manganese dioxides and their surface properties at the solid-aqueous solution interface were investigated. The studied series ranged from ramsdellite to pyrolusite and encompassed disordered MD samples. The structural model used takes into account structural defects: Pr (rate of pyrolusite intergrowth) and Tw (rate of microtwinning). Water adsorption isotherms showed that the cross sectional area of water molecules adsorbed in the first monolayer is positively correlated to Pr. Titration of the surface charge of the MD series evidenced a positive linear relationship between the PZC and Pr (Pr=0, Tw=0, PZC=1 for ramsdellite; Pr=1, Tw=0, PZC=7.3 for pyrolusite; γ-MD with intermediate values of Pr (0.2 to 0.45) have increasing PZC values). The rate of microtwinning appeared as a secondary factor for the increase of the PZC. The above correlations are explained by the chemical defects at the origin of the structural disorder, respectively Mn3+/Mn4+ substitution for Pr and Mn vacancies for Tw, which result in proton affinity and thus in increased PZC. The experimental results are compared with data collected in the literature for manganese dioxides as well as for dioxides of transition elements with tetragonal structure.
Structural effects in photopolymerized sodium AMPS hydrogels crosslinked with poly(ethylene glycol) diacrylate for use as burn dressings (2013)

Synthetic hydrogel polymers were prepared by free radical photopolymerization in aqueous solution of the sodium salt of 2-acrylamido-2-methylpropane sulfonic acid (Na-AMPS). Poly(ethylene glycol) diacrylate (PEGDA) and 4,4'-azo-bis(4-cyanopentanoic acid) were used as the crosslinker and UV-photoinitiator, respectively. The effects of varying the Na-AMPS monomer concentration within the range of 30-50% w/v and the crosslinker concentration within the range of 0.1-1.0% mol (relative to monomer) were studied in terms of their influence on water absorption properties. The hydrogel sheets exhibited extremely high swelling capacities in aqueous media which were dependent on monomer concentration, crosslink density, and the ionic strength and composition of the immersion medium. The effects of varying the number-average molecular weight of the PEGDA crosslinker from [Formula: see text] = 250 to 700 were also investigated. Interestingly, it was found that increasing the molecular weight and therefore the crosslink length at constant crosslink density decreased both the rate of water absorption and the equilibrium water content. Cytotoxicity testing by the direct contact method with mouse fibroblast L929 cells indicated that the synthesized hydrogels were nontoxic. On the basis of these results, it is considered that photopolymerized Na-AMPS hydrogels crosslinked with PEGDA show considerable potential for biomedical use as dressings for partial thickness burns. This paper describes some structural effects which are relevant to their design as biomaterials for this particular application.
A Soldier's Experience in New Mexico (1949)

spent his boyhood in Boston, and went to sea at 13 years of age, round Cape Horn in the sailing vessel, Chile, Capt.Knowles; was with him five years trading on the coast, of Peru-Followed the sea until 1849, then went to California in May 1849-Grass valley, northern J;Ilines, until the war broke out in 1861.Enlisted as a common soldier in 1861, in Company D. 1st Cav.Cal.Vol.-went down to Lower California, Los Angeles & San Bernardino.There we had skir.., mishes and put down the rebellion there; then were ordered to Tucson, Arizona,; we fortified at Pimo villages and waited for the main column to come up.Our first engagement was at Capache Pass with Hunter's rebel pickets.There we took 4 prisoners, and from them we got information how to advance.From there we were orde~ed to New Mexico.Gen. Sibley, a rebel, had possession of Las Cruces, of southern N. M.
Optimal Storage of Photon States in Optically Dense Atomic Media (2006)

We derive an optimal control strategy for storage and retrieval of a photon wavepacket of any given shape in a Lambda-type atomic medium with a limited optical depth. The control is provided by an appropriately shaped classical laser field. We present a universal physical picture encompassing different pulse-storage techniques ranging from adiabatic reduction of the photon group velocity and pulse-propagation control via off-resonant Raman fields to photon-echo based approaches. When properly optimized, all three approaches yield identical maximum efficiencies, which only depend on the optical depth of the medium. Extending the model to include Doppler broadening, we find the surprising result that at high enough optical depth all atoms contribute coherently as if the medium were homogeneously broadened.
GCU for Megawatt Class Directed Energy Weapons Pulse Generators (2006)

<div class="htmlview paragraph">Directed Energy weapon (DEW) systems are being developed for both ground and airborne applications. Typically, they consist of microwave or laser powered guns. Both the microwave application and the diode based laser applications require significant amount of power. This power ranges from several hundred kilowatts (kW) for microwave applications to Megawatts (MW) for laser applications. The laser application requires that the full power be available for short duration, typically 5 seconds, which could be repeated several times with short pauses in between. The control of a generator, which delivers Megawatt of the intermittent power greatly differs from the of normal steady state generator control. It poses significant challenges.</div> <div class="htmlview paragraph">Application of power (and for this matter its removal) is a transient phenomenon that takes time and its effects ripple through the whole system. In the case at hand, the large applied power, which is required for a short duration, can have a more significant effect on the system. Furthermore, it is imperative that the full power will be available for the required duration with no degradation in quality on both ends (application and removal). There are four entities that interact affecting the performance of the system:</div> <div class="htmlview paragraph"> <ul class="list disc"> <li class="list-item"><div class="htmlview paragraph">Controls: The generator regulator control loop</div></li> <li class="list-item"><div class="htmlview paragraph">Power Generation: The generator electromagnetic and mechanical properties</div></li> <li class="list-item"><div class="htmlview paragraph">Propulsion: The engine / FADEC transient performance characteristics</div></li> <li class="list-item"><div class="htmlview paragraph">Load: Load transients and feeder impedances</div></li> </ul> </div> <div class="htmlview paragraph">Innovative Power Solutions and PC Krause and Associates under AF SBIR program conducted the investigation of different systems approaches to design a MW Digital Generator Control Unit (MDGCU) and selected the winning topology. The final MDGCU will control a class of 1MW continuous or intermittent generators (<span class="xref">Figure 1</span> shows IPS designed 1MW intermittent generator).</div>
Structure-controlled magnetic anisotropy in ferromagnetic semiconductor superlattices (2004)

We present experimental studies of the in-plane magnetic anisotropy of ferromagnetic semiconductor superlattices. The samples have half-monolayer MnAs planes that alternate with GaAs spacers of thickness $t=28,$ 42, and 56 \AA{}. For the lowest-t samples, planar Hall effect and magnetization data indicate domain-wall-mediated magnetic switching between predominantly cubic easy axes, while samples with larger t exhibit uniaxial anisotropy. The data demonstrate that the structure of ferromagnetic semiconductor superlattices controls their magnetic anisotropy.
Deleted in Polyposis 1-like 1 Gene (<i>Dp1l1</i>): A Novel Gene Richly Expressed in Retinal Ganglion Cells (2005)

TB2-like 1 is a membrane protein that belongs to the YOP1/TB2/DP1/HVA22 family, and it probably plays an important role in intracellular membrane trafficking in RGCs, based on the properties of other homologous proteins.