gebhart/patrepeval huggingface dataset:
Disturbance of 3D velocity profiles induced by an IVUS catheter: evaluation with computational fluid dynamics (2002)

New IVUS-based blood velocity profile measurements are under development For these velocity measurements catheter placement in an artery is necessary, but induces disturbances in the native velocity profiles. To what degree the velocity profiles are disturbed by the catheter is studied by computational fluid dynamics. Therefore a straight tube having a catheter inside, is studied for 4 inflow velocities (0.05, 0.1, 0.2, 0.4 m/s) and two catheter positions (in the center and out of the center of the tube). The influence of the catheter size on the velocity profiles is studied as well. Central catheter placement reduced the peak to mean velocity ratio, compared to no catheter inside the tube, by 24%. In contrast, catheter placement out of the center of the tube increased the peak to mean velocity ratio by 14%. These values are independent of the inflow velocities and minimally dependent on changes in catheter size. The shear stress values, however, are dependent on both catheter location and catheter size.
Design and process modeling for the manufacture by extrusion of recycled polyethylene terephthalate and low density polyethylene nanocomposites reinforced with cellulose nanocrystals. (2015)

International audience
Fast and non-destructive vector field magnetometry with cold atomic ensembles (2013)

This paper reports on a fast, nondestructive and sensitive measurement technique that uses atomic spin precession and non-destructive Faraday rotation probing to measure all three components of the magnetic field with kHz bandwidth. In contrast to other vector magnetometer techniques that modulate an applied magnetic field, here the initial atomic polarization is modulated and the magnetic field components are extracted from the resulting free-induction decay (FID) signal, monitored via paramagnetic Faraday rotation. An ensemble of up to 10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">6</sup> cold <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">87</sup> Rb in the F = 1 hyperfine ground state was used and held in an optical trap as the field sensor.
General discussion (1968)

E. Yeager, B. E. Conway, T. Kuwana, J. W. Strojek, Wm. Von Benken, N. S. Hush, N. Winograd, V. S. Srinivasan, M. E. Peover, Z. R. Grabowski, M. S. Balasiewicz, Albery, P. Zuman, H. Nieboer, B. Czochralska, J. Jordan, G. J. Hoytink, R. Parsons and A. J. Bard, Discuss. Faraday Soc., 1968, 45, 175 DOI: 10.1039/DF9684500175
(Invited) Electropolymerized Poly(para-phenylene)vinylene Films onto and Inside Porous Si (2010)

The electrochemical deposition of poly(para-phenylene)vinylene (PPV) into the pores of porous silicon (PSi) has been investigated using acetonitrile as solvent and p-xylylene-α,α'-bis(triphenylphosphonium chloride as precursor. PPV was successfully deposited onto various Si substrates and PSi layers. It was also deposited inside p+-type and p-type PSi. The as-deposited PPV is strongly luminescent. The deposition was confirmed by optical (photoluminescence, reflectivity) and structural analysis (FTIR, SEM). The deposited PPV was smooth without peeling on PSi layers. With strongly luminescent n+-type PSi, the rate of the deposition was limited by the large resistivity of PSi. The deposition was found dramatically affected by the PSi nanostructure through the diffusion of precursors in the pores and charge carrier transport in PSi.
Simulation of multipath fading/ghosting for analog and digital television transmission in broadcast channels (1992)

An approach to the simulation of many of the channel impairments attributed to multipath fading and ghosting of a television signal is discussed. The use of the Hewlett Packard 11759D Dynamic Ghosting Simulator, which is capable of generating fading models ranging from static transmission conditions to dynamic cases of airplane flutter, tower sway, and reception by a mobile receiver in the simulation is described. All of these conditions can be used to subject future receivers, equalizers, and ghost cancellation circuitries to field-testing within the laboratory environment.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
225. Studies in the azole series. Part XI. The interaction of α-amino-nitriles, hydrogen sulphide, and ketones (1949)

A. H. Cook, I. Heilbron and A. P. Mahadevan, J. Chem. Soc., 1949, 1061 DOI: 10.1039/JR9490001061
Automatic Morphological Assessment in a Transgenic CACNA1A Knockin Migraine Mouse Model in In-Vivo High-Resolution MRM (2006)

Because of its close genetic and physiological similarities to humans, as well as the ease with which its genome can be manipulated, the mouse became the mammalian model of choice for genetic research. A first step in describing the potential impact of a given genetic manipulation is the characterization of general morphology. The use of 3-dimensional imaging techniques with high spatial resolution, such as magnetic resonance microscopy (MRM), became crucial because such imaging tools can expedite anatomical phenotyping in the genetically altered mice. In this paper we describe a fully automatic MRM image brain segmentation method and its application to phenotypical characterization of brain structures in a migraine mouse model, assessing volume and morphology of the cerebellar white matter and the brain ventricles. Our segmentation is atlas-based and is designed for in-vivo MRM image analysis
Estrogen Therapy and Coronary Artery Disease: Experimental Studies in Pigeons (1970)

No AccessJournal of Urology1 Jan 1970Estrogen Therapy and Coronary Artery Disease: Experimental Studies in Pigeons Kamal A. Hanash, Bruce A. Kottke, Jacques V. Souadjian, Laurence F. Greene, and Jack L. Titus Kamal A. HanashKamal A. Hanash More articles by this author , Bruce A. KottkeBruce A. Kottke More articles by this author , Jacques V. SouadjianJacques V. Souadjian More articles by this author , Laurence F. GreeneLaurence F. Greene More articles by this author , and Jack L. TitusJack L. Titus More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)61897-4AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "Estrogen Therapy and Coronary Artery Disease: Experimental Studies in Pigeons." The Journal of Urology, 103(1), pp. 84–85 © 1970 by The American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 103Issue 1January 1970Page: 84-85 Advertisement Copyright & Permissions© 1970 by The American Urological Association Education and Research, Inc.MetricsAuthor Information Kamal A. Hanash More articles by this author Bruce A. Kottke More articles by this author Jacques V. Souadjian More articles by this author Laurence F. Greene More articles by this author Jack L. Titus More articles by this author Expand All Advertisement PDF downloadLoading ...
Self-assembly of enantiopure domains: The case of indigo on Cu(111) (2010)

The adsorption of indigo molecules on Cu(111) was investigated by low temperature (5 K) scanning tunneling microscopy from the isolated single molecule regime to one monolayer. Structural optimization and image calculations demonstrate that the molecules are in a physisorbed state. Because of the reduced symmetry at the surface, single molecules acquire a chiral character upon adsorption leading to a two-dimensional (2D) chirality. They adopt two adsorption configurations, related by a mirror symmetry of the substrate, each with a distinct molecular orientation. Consequently, the 2D chirality is expressed by the orientation of the molecule. For higher coverage, molecules self-assemble by hydrogen bonding in nearly homochiral molecular chains, whose orientation is determined by the orientation taken by the isolated molecules. When the coverage approaches one monolayer, these chains pack into domains. Finally, the completion of the monolayer induces the expulsion of the molecules of the wrong chirality that are still in these domains, leading to perfect resolution in enantiopure domains.
Glucose Control, Disease Burden, and Educational Gaps in People With Type 1 Diabetes: Exploratory Study of an Integrated Mobile Diabetes App (2018)

An integrated mobile diabetes app has the potential to improve diabetes self-management and provide tailored educational support, which may decrease disease burden and benefit diabetes control.
Influence of alkali activators on thermo-physical properties of ecofriendly unfired clay bricks from anthill mounds (2021)

This experiment studied the effect of alkali activators on clay from anthill mounds which was blended with a small proportion of cement to develop eco-friendly unfired bricks. Physical, wet and dry compressive strength tests were investigated and the results were analysed using one-way ANOVA. Thermal conductivity and thermal diffusivity of the unfired bricks were also studied using Hot Disc Thermal Constant Analyzer. The microstructures of the unfired bricks were also analysed with scanning electron microscope equipment. The results of the physical tests were significantly higher at p < 0.05 for unfired bricks made up of 0.5% and 1% weights of calcium chloride and sodium hydroxide at a constant value of 1% weight of sodium silicate more than those made from other amounts of activators. The thermal performance values showed that the bricks are good insulators and could be used for the construction of structure requiring little thermal fluctuations. The study has shown that improved environment-friendly unfired clay bricks could be developed from the mixture of clay samples sourced from anthill mounds and alkali activators in addition to a little proportion of cement. These could be suitable for the construction of grain silos, low-cost structures and short-term shelters in low-income countries.
Parsons, Alfred, and Abbey, Edwin [1884] March 14 (1884)

copy of published letter from Jobe, August, 2000; transcription only; also addressed to Edwin A. Abbey
Short and long-term single-centre experience with an S-shaped unipolar lead for left ventricular pacing (2003)

The S-shaped unipolar lead evaluated in this study provides stable long-term position and pacing thresholds. Recent improvement of this S-shaped lead model will hopefully reduce the rate of implantation failures and acute dislodgements.
Optical Properties of Evaporated InSb Films (1961)

Get PDF Email Share Share with Facebook Tweet This Post on reddit Share with LinkedIn Add to CiteULike Add to Mendeley Add to BibSonomy Get Citation Copy Citation Text Roy F. Potter and George G. Kretschmar, "Optical Properties of Evaporated InSb Films," J. Opt. Soc. Am. 51, 693_1-696 (1961) Export Citation BibTex Endnote (RIS) HTML Plain Text Citation alert Save article
ChemInform Abstract: Synthesis of Optically Active 2,2′‐Diselenocyanato‐1,1′‐binaphthyl and Its Molecular Structure. Hypervalent Nature of Divalent Selenium Atom in Crystal State. (1988)

Abstract Starting with the optically active diamine (I), the diselenocyanato derivative (IV) is prepared by diazotization, followed by reaction with potassium selenocyanate (III).
Fetal Microchimerism in Women with Breast Cancer (2007)

Fetal microchimerism (FMc) describes long-term persistence of small numbers of fetal-derived allogeneic cells in the mother. Although FMc has been implicated as a mechanism of autoimmune disease, it may confer a beneficial effect with immune surveillance of malignant cells. We hypothesized that allogeneic FMc imparts a protective effect against breast cancer. Two observations provided a rationale for the study hypothesis. First, allogeneic cells convey risk reduction for recurrent malignancy in hematopoietic cell transplantation. Second, reduced risk of breast cancer is well recognized among parous compared with nulliparous women. As an initial test of the hypothesis, we investigated 82 women, 35 with breast cancer and 47 who were healthy, for male DNA in peripheral blood, presumed from a prior pregnancy with a male fetus. The prevalence and levels of male DNA were determined by real-time quantitative PCR for the Y chromosome-specific gene DYS14 in DNA extracted from peripheral blood mononuclear cells. FMc was found significantly more often in healthy women than women with breast cancer (43% versus 14%, respectively). Considering the absence of FMc as a risk factor, the odds ratio was 4.4 [95% confidence intervals (95% CI), 1.34-16.99; P = 0.006]. Restricting analysis to women known to had given birth to a son, the odds ratio was 5.9 (95% CI, 1.26-6.69; P = 0.01). Our findings indicate that allogeneic FMc may contribute to reduction in risk of breast cancer. Further studies are indicated and, if confirmed, extended studies to examine whether allogeneic immune surveillance from FMc is deficient in women with breast cancer.
1,3‐Bis(1‐phenylvinyl)benzene and its reactions with electron transfer reagents (1977)

Abstract The investigation of electron transfer and subsequent reactions of divinylidene compounds not capable of anionic homopolymerization was extended to 1,3‐bis(1‐phenylvinyl)benzene ( 2 ). A new method for the preparation of this compound is described. Its reaction with Li, Na, and K as electron transfer reagents in THF as solvent results in an increasing yield in polymeric combination products of the radical anions formed primarily with increasing reducing power of the alkali metal. The main product, however, in any case is the cyclic dimeric tetra‐anion of 2 , which upon protonation yields 1,4,11,14‐tetraphenyl[4.4]metacyclophane ( 3 ).
CHEMICAL EVALUATIONS FOR CONTROL OF ROSE CHAFER ON GRAPES, 2004 (2005)

Treatments were evaluated for efficacy against the rose chafer in an experimental 'Clinton' vineyard at Wooster, Ohio. Plots consisted of two grape vines, with 4 replications per treatment in a RCB design. Treatments were applied as foliar sprays at a rate of 100 gpa on 8 Jun. A hand-held CO2 sprayer operating at 45 psi and equipped with a 9505-E-TeeJet nozzle was used to apply treatments. On 0, 1, 2 and 7 DAT four leaves were randomly chosen from each treatment and placed in 1 gal ice cream containers along with 10 adult beetles. The 1 gal containers were modified by placing plastic liners inside and cheese cloth over the top. After 24 hr a count of the number of dead beetles was taken. Data were analyxed using ANOVA and means were separated using an F-protected LSD (P ≤ 0.05).
An fMRI investigation of a memory guided vergence task: Insights to the parahippocampal area (2012)

This investigation sought to systematic study the parahippocampal area using three types of vergence eye movement tasks that utilized different demands on visual memory. The percent volume change of the functional activity in the posterior parahippocampal area (PPHA) was quantified for three different experimental paradigms that stimulated vergence eye movements: random tracking versus fixation; predictable tracking versus random tracking; and memory-guided task. A general linear model (GLM) was used to determine functional activity for each of the three vergence experiments. The average signal percent change for both the PPHA and frontal eye fields (FEF) was compared for each vergence task. Significant percent change in the average signal from the voxels in the PPHA was observed for all experiments (p <; 0.005), whereas no such significant change was observed for the FEF (p >; 0.06). Lastly, percent volume change was also quantified for the PPHA among experiments. Percent volume change in the PPHA was greater for the memory-guided vergence task and the change was significant across all the experiments, (p<;0.02). This suggests that when utilization of working memory is required, the PPHA functions as one of the regions for a vergence eye movement dependent memory task.
Measurements of the Kinetic Inductance of Superconducting Linear Structures (1969)

The kinetic inductance Lk is associated with the inertial mass of the current carriers. For a long superconductor of length l and very small cross-sectional area σ, Lk = (m* / nse*2) (l/σ) and is the main contribution to the temperature-dependent inductance LT. We have measured LT in superconducting tin wires and thin film meander lines by a technique which uses a counter to determine frequency changes of a 15 MHz tunnel-diode oscillator whose tank circuit contains LT. The measured frequency changes are proportional to z = [λ(t)/λ(0)]BCS for wires and thick films; for thin films the frequency changes are proportional to z2. This result agrees with calculations of LT from the London theory and the values of λ(0) agree well with the values expected for these samples. This technique allows measurement of the carrier concentration or penetration depth in thin films over the whole H, T plane of the superconducting state and can be independent of the penetration law assumed. Frequency shifts observed with thin film alumimum meander lines have been used to detect changes of temperature of 5∼10−7 °K, changes of magnetic field of 10−5 G, and changes of current associated with one quantum in a flux quantum magnetometer.
1P-104 Ab initio QM/MM study of photosynthesis reaction center of Rhodobacter sphaeroides(Electronic state, The 47th Annual Meeting of the Biophysical Society of Japan) (2009)

Thc Length and Viscosity Dependence of End-to-end Collision RatesinSing]e-s{randedDNA TakanoriUzawa(1).RyanChcng{?).Dmiti'iiMakarov{2}.KevinPlaxco(3)(rl)Hokkaido UniversiD,.' (2) 7ke VniveJ'sity oj' 7lexas,' r3) Un-,ersity ofCcttijbrnitt Santa Barbara} KaoruScience} Interaction between tetruplex and telomeric DNA binding protein Potl Kaneda {1), Hidetaka Terigoc (1) ((i) structure of mouse tctomeric DNA domains ol' mousc tc]omere bind{ng Faculty qt' Science, Tok}'o Universi4' qf see ITPS-04 see 1TP5-02 IP-098 VVUhAmeiXC[S6E ± etz/SOE-tawatsakOzazaItVR
O1‐01‐03: Meta‐Analysis of Rare CLU Variants Shows Association with Alzheimer's Risk and Calls Attention To The CLU Beta‐Subunit (2011)

Two large independent GWA studies showed that the clusterin gene (CLU) was significantly associated with Alzheimer's disease. In this study we have performed a detailed genetic CLU analysis on a Flanders-Belgian cohort in the first stage, a French cohort of the original GWA study in the second stage, and on a large meta-analysis. We will hereby focus on the rare CLU findings. Exons encoding the CLU beta-chain were sequenced in a Belgian (849 AD patients, 659 control individuals) and French cohort (1465 AD patients, 716 healthy individuals). Allele frequencies were collapsed across the beta-chain. The impact of non-synonymous variants on protein function was predicted using in silico programs (PolyPhen, SIFT software). To increase the number of observations on rare variants, we meta-analyzed all possible pathogenic variants in the beta-chain, combining information on a total of 5,235 AD patients and control individuals. Several rare variants (MAF<1%) were found throughout the CLU beta-chain in the Belgian cohort. Interestingly, five were predicted to have possible and probable damaging effects on CLU protein function and were found in AD patients only; one deletion (p.T445_D447del) and four missense mutations (p.R338W, p.T345M,p.N369H, p.T440M). Comparing the allele frequency of detected variants between patients and healthy individuals, we observed an almost four times increase of rare protein-affecting mutations in the CLU beta-chain sequence in AD patients compared to variants found in control individuals only (p=0.02). Sequencing the CLU beta-chain in the second cohort revealed 3 patient-specific predicted pathogenic missense mutations that were also identified in Belgian patients, and one novel mutation detected in one French patient (p.I301Nfs). The meta-analysis combining both our novel sequence information (Belgian and French cohort) as previously published information (Portuguese, UK and US-Caucasian cohort) on rare predicted pathogenic variants in the CLU beta-chain (p.R338W, p.N369H, p.T445_D447del, p.P322L, p.I301Nfs, p.R338Q), confirmed our finding that rare pathogenic variants in the CLU beta-chain were more often observed in AD patients compared to healthy controls (ORMH2.76 [95%, CI 1.35-5.65]; p=0.0045, pwolf=0.4). Our findings call attention to the CLU beta-subunit in AD pathogenesis and warrant further functional elucidation of rare CLU variants in disease.
A Knowledge-Based System For The Recognition Of Roads On SPOT Satellite Images (1989)

Due to the resolution of current satellite imagery (e.g. SPOT), the extraction of roads and linear networks from satellite data has become a feasible - although labour-intensive - task for a human expert. This interpretation problem relies on structural image recognition as well as on expertise in combining data sources external to the image data (e.g. topography, landcover classification). In this paper different knowledge sources employed by human interpreters are discussed. Ways to implement these sources using current knowledge-based tools are suggested. A practical case study of knowledge integration is described.
Structural Basis for the Interaction of Lactivicins with Serine β-Lactamases (2010)

Lactivicin (LTV) is a natural non-beta-lactam antibiotic that inhibits penicillin-binding proteins and serine beta-lactamases. A crystal structure of a BS3-LTV complex reveals that, as for its reaction with PBPs, LTV reacts with the nucleophilic serine and that cycloserine and lactone rings of LTV are opened. This structure, together with reported structures of PBP1b with lactivicins, provides a basis for developing improved lactivicin-based gamma-lactam antibiotics.
MEMS module integration into SiGe BiCMOS technology for embedded system applications (2012)

The introduction of radio frequency micro-electro-mechanical systems (RFMEMS) as a monolithic option into state-of-the-art Si/SiGe BiCMOS foundry processes has paved the way for single chip radio frequency microsystems at millimeter wave frequencies. Deep silicon substrate etch techniques have also been developed to prevent high substrate losses which help in achieving high performance passive components at mm-wave frequencies. Using the same process techniques, realization of highly efficient on-chip antennas has become feasible, which in the millimeter-wave range no longer come with a hefty chip real estate penalty. In this paper, the current status of embedded BiCMOS+MEMS technology development is presented. Reconfigurable circuits using embedded RFMEMS switches and mm-wave transceivers with on-chip antennas are also discussed as application examples.
Arf-induced turnover of the nucleolar nucleophosmin-associated SUMO-2/3 protease Senp3 (2008)

The stabilization and subcellular localization of the p19(Arf) tumor suppressor protein and the SUMO-2/3 deconjugating protease Senp3 each depend upon their binding to the abundant nucleolar protein nucleophosmin (Npm/B23). Senp3 and p19(Arf) antagonize each other's functions in regulating the SUMOylation of target proteins including Npm itself. The p19(Arf) protein triggers the sequential phosphorylation, polyubiquitination and rapid proteasomal degradation of Senp3, and this ability of p19(Arf) to accelerate Senp3 turnover also depends on the presence of Npm. In turn, endogenous p19(Arf) and Senp3 are both destabilized in viable Npm-null mouse embryo fibroblasts (that also lack p53), and reintroduction of the human NPM protein into these cells reverses this phenotype. NPM mutants that retain their acidic and oligomerization domains can re-stabilize both p19(Arf) and Senp3 in this setting, but the nucleolar localization of NPM is not strictly required for these effects. Knockdown of Senp3 with shRNAs mimics the antiproliferative functions of p19(Arf) in cells that lack p53 alone or in triple knock-out cells that lack the Arf, Mdm2 and p53 genes. These findings reinforce the hypothesis that the p53-independent tumor suppressive functions of p19(Arf) may be mediated by its ability to antagonize Senp3, thereby inducing cell cycle arrest by abnormally elevating the cellular levels of SUMOylated proteins.