gebhart/patrepeval huggingface dataset:
Anti-cardiolipin antibodies and circulating immune complexes in type 1 diabetes mellitus: increased prevalence and relation to vascular complications (1999)

Anti-cardiolipin antibodies, oxidatively modified low-density lipoproteins (oxLDL) and circulating immune complexes are humoral factors that have been linked to vascular damage. To analyse their possible role in the vascular complications in type 1 diabetes mellitus, we investigated patients with and without vascular complications (retinopathy, nephropathy, polyneuropathy, foot ulcers). The patients were matched for age, sex and duration of diabetes. The patients were also compared with 102 healthy individuals. Anti-cardiolipin antibodies of IgG and IgA type were more common in patients compared with healthy individuals. There was no difference between patients with and without vascular complications. There was no increased prevalence of IgM anti-cardiolipin antibodies, but the levels of these antibodies were higher in patients with vascular complications compared with patients without complications and controls. Eighty-three percent of patients had circulating immune complexes in comparison with 5% of healthy individuals. Such complexes were more common in patients with complications. Both the prevalence and the levels of immune complexes were higher in patients with null alleles of complement factor C4. Patients with vascular complications had higher prevalence of C4A than of C4B null alleles. Anti-cardiolipin antibodies were present in higher relative concentrations in immune complex form than in serum in all six patients analysed. There was no increased prevalence of antibodies against oxidatively modified LDL in the patients. The higher prevalence and levels of anti-cardiolipin antibodies and circulating immune complexes in patients with vascular complications suggests that these humoral factors might be involved in the vascular complications of type 1 diabetes mellitus.
An octameric titanium oxo metallacycle with host–guest interactions (1995)

Treatment of TiCl4 with carboxylic acids RCO2H (R = C6F5, CH2C6F5, CH2OC6F5) yields a series of titanium oxo compounds; the X-ray molecular structure of [TiO(O2CC6F5)2] reveals an octameric unit and a unique 16-membered Ti8O8 ring, with two toluene molecules encapsulated above and below the ring in the molecular cavity.
Optimization of optical properties of photonic crystal fibers infiltrated with carbon tetrachloride for supercontinuum generation with subnanojoule femtosecond pulses (2018)

A photonic crystal fiber (PCF) made of fused silica glass, infiltrated with carbon tetrachloride (CCl<sub>4</sub>), is proposed as a new source of supercontinuum (SC) light. Guiding properties in terms of effective refractive index, attenuation, and dispersion of the fundamental mode are studied numerically. As a result, two optimized structures are selected and verified against SC generation in detail. The dispersion characteristic of the first structure has the zero-dispersion wavelength at 1.252 μm, while the dispersion characteristic of the second structure is all-normal and equals -4.37 ps·nm<sup>-1</sup>·km<sup>-1</sup> at 1.55 μm. SC generation was demonstrated for the wavelengths 1.064 μm, 1.35 μm, and 1.55 μm. We prove the possibility of coherent, octave-spanning SC generation with 300 fs pulses with only 0.8 nJ of energy in-coupled into the core with each of the studied structures. Proposed fibers are fully compatible with all-silica fiber systems and PCFs with wide mode area, and can also be used for all-fiber SC sources. The proposed solution may lead to new low-cost all-fiber optical systems.
Optical monitoring of ultrasound interaction with blood vessels in transparent fish after injection with contrast agents (2003)

The goal of this research is to study the ultrasonic therapeutic effects on the blood vessels of animals whose vessels are optically transparent. Glass catfish were used in these experiments Anaesthetized fish were injected with Optison using microinjection techniques. Two focused transducers were used to cover a frequency range of 0.7-3.3 MHz. An inverted microscope combined with a digital camera and video monitor was used to optically monitor and record ultrasound interaction with the blood vessels in the tail of the anaesthetized fish at 200x magnification. The fish were insonified at average acoustic pressures ranging from 0.6-15 MPa. Sonications were pulsed with various burst lengths and a pulse repetition frequency of 1 Hz for 20 sec duration. For the 1.091 MHz sonications, the first type of damage that occurred due to the ultrasound interaction was structural damage to the cartilage rods that comprise the tail of the fish and was characterized by a disintegration of the lining of the rod. Damage to the rods occurred starting at 4.0 MPa, 4.4 MPa, 4.7 MPa, and 6.8 MPa for the 100 msec, 10 msec, 1 msec, and 100 /spl mu/sec sonications, respectively. The formation of large gas bubbles was observed in the blood vessels of the fish at threshold values of 4.4 MPa, 4.4 MPa, and 6.1 MPa, for the 100 msec, 10 msec, and 1 msec sonications, respectively. At 1.091 MHz, hemorrhage thresholds were observed at 4.7 MPa, 5.4 MPa, and 7.1 MPa, respectively, for the three burst lengths. No damage was observed in any fish using a 10 /spl mu/sec burst length at 1.091 MHz or the 3.273 MHz sonications at the pressures applied. The 2.273 MHz sonications induced very little damage, only to the cartilage rods in the tail.
Influence of the molecular weight of ethylene vinyl acetate copolymers on the flow and mechanical properties of uncompatibilized polystyrene/ethylene-vinyl acetate copolymer blends (2001)

Rubber-toughened polystyrene (PS) has been extensively studied and is a well-established material. However, the use of thermoplastic elastomers to toughen PS is new and not well understood. In this study, three types of ethylene vinyl acetate (EVA) copolymers with the same vinyl acetate (VA) content (27.2–28.8 wt %) but with different melt flow indexes (MFI; g (10 min)−1) of 365–440 (Elvax 210), 38.0–48.0 (Elvax 240) and 2.6–3.4 (Elvax 265) were used as impact modifiers for PS. The uncompatibilized blend systems at different compositions were prepared using a twin-screw extruder and injection moulding to produce the required test pieces. The viscosity of the dispersed phase (EVA) has a significant effect on the mechanical properties of the blends. Rheological studies show that uncompatibilized PS/EVA265 blends exhibit some degree of compatibility when the amount of EVA265 added is below 30 wt %. These results indicate that EVA265 with the lowest melt flow index or highest molecular weight is the most effective impact modifier for PS. The mechanism for such behaviour is still unclear. © 2001 Society of Chemical Industry
Scalable Emulation of Enterprise Systems (2009)

Testing enterprise software that communicates with a large number of other software systems is a challenging task as it is often difficult to replicate the size and heterogeneity of large enterprise environments. In particular, it is challenging to conduct testing of non-functional properties related to scalability, performance, and robustness of enterprise software systems when deployed into such environments. In order to address this issue, we propose the use of a scalable emulation environment enabling non-functional testing of enterprise software in realistic and large-scale settings. In this paper, we illustrate our approach by using deterministic finite state machines to specify a scalable and interactive emulation of a modeled environment. To demonstrate the practicality and scalability of the approach, a prototype tool is presented that is used to emulate a large-scale environment of up to 10,000 endpoint systems for an enterprise class software system.
<b>Heptaphenylcycloheptatrienyl Anion, a Singlet with Potential Spin Degeneracy</b> (1962)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTHeptaphenylcycloheptatrienyl Anion, a Singlet with Potential Spin DegeneracyRonald. Breslow and Hai Won. ChangCite this: J. Am. Chem. Soc. 1962, 84, 8, 1484–1485Publication Date (Print):April 1, 1962Publication History Published online1 May 2002Published inissue 1 April 1962https://pubs.acs.org/doi/10.1021/ja00867a025https://doi.org/10.1021/ja00867a025research-articleACS PublicationsRequest reuse permissionsArticle Views90Altmetric-Citations15LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Nonlinear Model Predictive Control for Stochastic Differential Equation Systems (2018)

Using the Van der Pol oscillator model as an example, we provide a tutorial introduction to nonlinear model predictive control (NMPC) for systems governed by stochastic differential equations (SDEs) that are observed at discrete times. Such systems are called continuous-discrete systems and provides a natural representation of systems evolving in continuous-time. Furthermore, this representation directly facilities construction of the state estimator in the NMPC. We provide numerical details related to systematic model identification, state estimation, and optimization of dynamical systems that are relevant to the NMPC.
Reducing Downlink Signaling Traffic in Wireless Systems Using Mobile-Assisted Scheduling (2010)

We present an idea to reduce the part of the downlink signaling traffic in wireless multiple access systems that contains scheduling information. The theoretical basis of the scheme is that the scheduling decisions made by the base station are correlated with the CSI reports from the mobiles. This correlation can be exploited by the source coding scheme that is used to compress the scheduling maps before they are sent to the mobiles. In the proposed scheme, this idea is implemented by letting the mobiles make tentative scheduling decisions themselves, and then letting the base station transmit "agreement maps" instead of raw scheduling maps to the mobiles. The agreement maps have lower entropy and they require less resources to be transmitted than the original scheduling maps do. The improvement can be substantial.
Lektion 9: Grundlagen der Rheologie (2015)

No AccessTechnologie der KunststoffeOct 2015Lektion 9: Grundlagen der RheologieChristian Hopmann, Walter Michaeli, Helmut Greif, Leo WoltersChristian Hopmann, Walter Michaeli, Helmut Greif, Leo Woltershttps://doi.org/10.3139/9783446442078.009SectionsAboutPDF ToolsAdd to FavoritesDownload CitationTrack CitationsCopy LTI LinkPDF key 'share (en)' returned an object instead of string.FacebookTwitterEmailLinkedIn previous chapternext chapter FiguresReferencesRelatedDetails 2015Pages: 77-85Print ISBN: 978-3-446-44233-7eISBN: 978-3-446-44207-8 Copyright & Permissions© 2015 Carl Hanser Verlag GmbH & Co. KGPDF DownloadLoading ...
Pharmacological characterization of a small‐molecule agonist for the chemokine receptor CXCR3 (2011)

VUF10661, like CXCL11, activates both G protein-dependent and -independent signalling via the CXCR3 receptor, but probably exerts its effects from an allosteric binding site that is different from that for CXCL11. It could stabilize different receptor and/or β-arrestin conformations leading to differences in functional output. Such ligand-biased signalling might offer interesting options for the therapeutic use of CXCR3 agonists.
Oxygen Reduction Activity of Vapor-Grown Platinum Nanotubes (2013)

Supportless platinum nanotubes (PtNTs) were synthesized by the decomposition of platinum acetylacetonate vapor within anodic alumina templates at 210°C. As synthesized, the nanotubes are nanoparticulate aggregates composed of Pt crystallites approximately 3 nm in diameter and with a range of lengths from 1 μm to 20 μm. Annealing treatments result in crystallite growth and morphological evolution of the tubular nanostructures including the development of nanoscale porosity. In rotating disk electrode measurements carried out in 0.1 M HClO4, porous PtNTs annealed at 500°C exhibited a specific activity for oxygen reduction of 2390 ± 423 μA/cm2Pt at 0.9 V, comparable to bulk polycrystalline Pt. The electrochemical surface area of the annealed structures was a relatively low 10 m2/g, resulting in a moderate overall mass activity of 240 ± 41 mA/mgPt.
High-Dose Supplements of Vitamins C and E, Low-Dose Multivitamins, and the Risk of Age-related Cataract: A Population-based Prospective Cohort Study of Men (2013)

We examined the associations of high-dose supplements of vitamins C and E and low-dose multivitamins with the risk of age-related cataract among 31,120 Swedish men, aged 45-79 years, in a population-based prospective cohort. Dietary supplement use was assessed from a questionnaire at baseline in 1998. During follow-up (January 1998-December 2006), 2,963 incident age-related cataract cases were identified. The multivariable-adjusted hazard ratio for men using vitamin C supplements only was 1.21 (95% confidence interval (CI): 1.04, 1.41) in a comparison with that of non-supplement users. The hazard ratio for long-term vitamin C users (≥10 years before baseline) was 1.36 (95% CI: 1.02, 1.81). The risk of cataract with vitamin C use was stronger among older men (>65 years) (hazard ratio = 1.92, 95% CI: 1.41, 2.60) and corticosteroid users (hazard ratio = 2.11, 95% CI: 1.48, 3.02). The hazard ratio for vitamin E use only was 1.59 (95% CI: 1.12, 2.26). Use of multivitamins only or multiple supplements in addition to vitamin C or E was not associated with cataract risk. These results suggest that the use of high-dose (but not low-dose) single vitamin C or E supplements may increase the risk of age-related cataract. The risk may be even higher among older men, corticosteroid users, and long-term users.
ORGANOPHOSPHORUS COMPOUNDS: IX. DIARYL PHOSPHOROFLUORIDATES AND DIARYL PHOSPHOROFLUORIDOTHIOATES (1962)

Diaryl phosphorofluoridates and diaryl phosphorofluoridothioates were prepared and their properties investigated.
Profiling of Dataflow Programs Using Post Mortem Causation Traces (2012)

The natural representation of data streams, parallelism, and composition has made dataflow an attractive programming model for expressing a wide range of stream and media processing applications, and has led MPEG and ISO to base their latest video coding standards on this model. This paper describes and compares methodologies and metrics for the optimization of signal processing algorithms represented as dataflow programs. Our approach is based on the analysis of traces and addresses some of the complexity challenges that arise from the very large data sets that are required for evaluating real-world applications. The methodology and experimental results are demonstrated and evaluated in two at-size case studies, an MPEG-4 SP and an AVC/H.264 video decoders.
Subspace Inference for Bayesian Deep Learning (2019)

Bayesian inference was once a gold standard for learning with neural networks, providing accurate full predictive distributions and well calibrated uncertainty. However, scaling Bayesian inference techniques to deep neural networks is challenging due to the high dimensionality of the parameter space. In this paper, we construct low-dimensional subspaces of parameter space, such as the first principal components of the stochastic gradient descent (SGD) trajectory, which contain diverse sets of high performing models. In these subspaces, we are able to apply elliptical slice sampling and variational inference, which struggle in the full parameter space. We show that Bayesian model averaging over the induced posterior in these subspaces produces accurate predictions and well calibrated predictive uncertainty for both regression and image classification.
In Situ Scanning Tunneling Microscopy of Polycrystalline Platinum Electrodes under Potential Control: Copper Electrodeposition and Pyrrole Electropolymerization (1989)

The surface changes of Pt electrodes immersed in solution under potential control were studied by scanning tunneling microscopy. Various structures were observed on a polished, flame‐annealed‐quenched polycrystalline electrode. Extended cycling of the electrode in between the regions where an adsorbed oxide film forms and is removed causes significant roughening of the electrode surface. The electrodeposition of copper on polycrystalline Pt and of polypyrrole on a Pt film on mica was also investigated.
Synthesen in der heterocyclischen Reihe, XV. Über 1‐[3‐Aryl‐isoindolyl‐(1)‐imino]‐3‐aryl‐1<i>H</i>‐isoindole (1972)

Abstract Aus o ‐Cyan‐benzophenon und Formamid erhält man neben 3‐Formamino‐1‐oxo‐3‐phenyl‐isoindolin ( 5 ) das rotviolette 1‐[3‐Phenyl‐isoindolyl‐(1)‐imino]‐3‐phenyl‐1 H ‐isoindol ( 1 ). 1 sowie an den Phenylkernen substituierte Analoga von 1 entstehen aus Phthalodinitrilen und Arylmagnesiumbromiden.
Establishment of a small animal model for human Helicobacter pylori infection using germ-free mouse. (1994)

We therefore suggest that the growth of H. pylori may be suppressed by the immunological system and eradicated by Lactobacilli previously inhabiting the stomach.
MİLENYUM ÇAĞININ ENERJİ PROBLEMİ: ELEKTRİK SEKTÖRÜ ÇATIŞMALARI (2015)

İnsanlığın evrimi ile enerji ihtiyacı gereksinimi birbirine sıkı sıkıya bağlı bulunmaktadır.Toplumlaşma bilincinin ortaya çıkmasıyla bütün ülkelerin şehirleşme süreci hızlanmıştır. Şehirleşme süreci toplumun ısınma, aydınlanma ve diğer barınma ihtiyacının gereksinim duyduğu elektrik enerjisi tüketimini de artırmıştır. Gelişmiş ülkelerin şehirleşme süreci, durağan nüfus büyümeleriyle bıraktığımız yüz yıl içinde tamamlanırken gelişmekte olan ülkelerde katlanan nüfus yığınlarıyla hızlanmıştır. Bu durum dünya elektrik talebinde ani sıçramalara neden olmuştur. 2000&#039;li yıllara gelindiğinde artık hem gelişmiş hem de gelişmekte olan ülkeler elektrik üretiminde kullanılabilecek bütün kaynakların rasyonel dağılımı konusunda çalışmalar yapmak zorunda kalmışlardır. Bu çalışmanın amacı artan teknolojik birikimle ortaya çıkan global elektrik enerjisi talebinin hangi tür kaynaklardan elde edildiğini incelemek ve küresel ısınmayla beraber çevresel faktörlerin önem kazandığı son yıllarda elektrik gücü yaratımında hangi tür kaynakları tercih ettikleri konusunda analiz yapabilmektedir. Çalışma içinde aynı zamanda üretim aşamasında kullanılan kaynakların yarattığı sektörler arası nasıl bir kazanç paylaşım mücadelesi sergilendiği gösterilmeye çalışılmaktadır. Bu çatışmanın, küresel ısınma, çevre kirliliği gibi dünyamızın yaşam alanını olumsuz etkileyecek faktörlerin önem kazanmasıyla, şiddetlenerek artmasına çalışma içinde dikkat çekilecektir.
Comparison of the autoradiographic binding distribution of [3H]‐gabapentin with excitatory amino acid receptor and amino acid uptake site distributions in rat brain (1996)

1. Gabapentin is a novel anticonvulsant with an unknown mechanism of action. Recent homogenate binding studies with [3H]-gabapentin have suggested a structure-activity relationship similar to that shown for the amino acid transport system responsible for the uptake of large neutral amino acids (LNAA). 2. The autoradiographic binding distribution of [3H]-gabapentin in rat brain was compared with the distributions for excitatory amino acid receptor subtypes and the uptake sites for excitatory and large neutral amino acids in consecutive rat brain sections. 3. Densitometric measurement of the autoradiographic images followed by normalisation with respect to the hippocampus CA1 stratum radiatum, was carried out before comparison of each binding distribution with that of [3H]-gabapentin by linear regression analysis. The correlation coefficients observed showed no absolute correlation was observed between the binding distributions of [3H]-gabapentin and those of the excitatory amino acid receptor subtypes. The acidic and large neutral amino acid uptake site distributions demonstrated a much closer correlation to the [3H]-gabapentin binding site distribution. The correlation coefficients for D-[3H]-aspartate, L-[3H]-leucine and L-[3H]-isoleucine binding site distributions were 0.76, 0.90 and 0.88 respectively. 4. Concentration-dependent inhibition by unlabelled gabapentin of autoradiographic binding of L-[3H]-leucine and L-[3H]-isoleucine was observed, with non-specific binding levels being reached at concentrations between 10 and 100 microM. 5. Excitotoxic quinolinic acid lesion studies in rat brain caudate putamen and autoradiography were carried out for the amino acid uptake sites mentioned above. The resulting glial infiltration of the lesioned areas was visualized by autoradiography using the peripheral benzodiazepine receptor specific ligand [3H]-PK11195. A significant decrease in binding density in the lesioned area compared with sham-operated animals was observed for D-[3H]-aspartate, L-[3H]-leucine, L-[3H]-isoleucine and [3H]-gabapentin, whilst [3H]-PK11195 showed a significant increase in binding density indicative of glial infiltration into the lesioned area. These results suggest that the gabapentin binding site and the acidic and LNAA uptake site may be present on cell bodies of a neuronal population of cells. 6. From these studies it appears that [3H]-gabapentin, L-[3H]-leucine and L-[3H]-isoleucine bind to the same site in rat brain. The inhibition of [3H]-gabapentin binding by the LNAA uptake system-specific ligand, BCH, suggests that [3H]-gabapentin may label this uptake site, termed system-L. Conversely these ligands could be labelling a novel site that coincidentally has a similar structure-activity relationship to this uptake site. These results suggest a novel mechanistically relevant site of action for gabapentin and may enable further anti-epileptic agents of this type to be developed.