gebhart/patrepeval huggingface dataset:
Quantitative two-dimensional echocardiographic analysis of regional wall motion in patients with perioperative myocardial infarction. (1984)

Regional left ventricular wall motion was evaluated by two-dimensional echocardiographic techniques with fixed- and floating-axis analytical algorithms in three groups of subjects: normal subjects (n = 15), patients undergoing uncomplicated coronary artery bypass graft surgery (CABG) (n = 10), and patients suffering perioperative myocardial infarction (n = 27). In patients undergoing uncomplicated CABG, fixed-axis analysis in the apical four-chamber view produced septal hypokinesis indistinguishable from the septal hypokinesis seen in patients with anterior myocardial infarction. In addition, fixed-axis analysis enhanced lateral wall motion so that patients with lateral myocardial infarction were classified as normal. Floating-axis analysis corrected these limitations by (1) producing regional left ventricular wall motion in the patients undergoing uncomplicated CABG, which was identical to that in normal subjects, and (2) producing regional left ventricular wall motion in patients with myocardial infarction that was hypokinetic in segments corresponding to the electrocardiographic area of involvement. In patients with new Q waves, fixed-axis analysis detected abnormalities of regional left ventricular wall motion in 24 of 34 (71%) electrocardiographically involved regions but also classified 44 of 100 segments in uncomplicated patients as abnormal. Floating-axis analysis detected regional left ventricular wall motion abnormalities in 30 of 34 patients (88%; p less than .05 vs fixed-axis analysis) and only 15 of 100 segments in patients undergoing uncomplicated CABG were classified as abnormal (p less than .001 vs fixed-axis analysis). We conclude that floating-axis analysis is a more accurate and clinically relevant method of evaluating regional left ventricular wall motion in patients undergoing CABG who suffer myocardial infarction as a perioperative complication.
Antennas with transmission-line interconnections (1970)

Arrays of cylindrical dipoles and monopoles are usually driven by means of interconnecting transmission lines, whereas analyses of such arrays are generally made in terms of currents or voltages with assigned relative amplitudes and phases at the individual input terminals. Moreover, it is commonly assumed that the distributions of current along all elements are the same and without phase variation. The properties of broadside and endfire arrays are treated with full consideration of interconnecting transmission lines and the effect of mutual coupling on the distributions of current. Driving-point admittances and field patterns of arrays of half-wave and full-wave elements are given. A novel broadside-endfire array is described.
Suppression of Insulator Charging During Secondary‐Ion Mass Spectroscopy and Scanning Electron Microscopy (1985)

Work with a hot stage capable of temperatures of up to 1200°C has shown that charging of insulating materials in a scanning electron microscope can be completely eliminated by heating the sample to several hundred degrees centigrade. A similar scheme was devised to eliminate charging in a secondary‐ion mass spectrometer in order to study oxygen‐18 concentration profiles in MgO. Before and during analysis the sample surface was exposed to a high‐energy electron beam. The mechanism responsible for the elimination of spurious charging is related to surface heating by the electron beam.
Scaling theory of the low-field Hall effect and magnetoresistance near a percolation threshold (1987)

Abstract The scaling theory of the low-magnetic-field Hall effect in a metal-non-metal mixture near its percolation threshold is reviewed and extended to discuss the magnetoresistance in low fields. It is shown that different types of critical behaviour are possible for the Hall coefficient and for the relative magnetoresistance of the mixture, depending upon the physical parameters of the mixture. A pair of new exponents are introduced to describe the critical behaviour of the second-order Hall contribution to the magnetoresistance of the mixture, and upper and lower bounds are suggested for their values.
Excimer laser induced ablation of polyetheretherketone, polyimide, and polytetrafluoroethylene (1992)

New experimental data on the photoablation rate of polyetheretherketone and Kapton film by 25 ns pulses of XeCl laser radiation are presented. The fluences used were in the range of 5–70 J/cm2. The etching rate increases with fluence up to about 50 J/cm2 and then saturates for both the polymers. The data can be described very well by the model proposed earlier by Srinivasan, Smrtic, and Babu (SSB), which includes both thermal and photochemical contributions to polymer ablation. This model is compared with that of Sauerbrey and Petit for describing the etch rate of polyimide with 308 nm laser pulses of various durations. It is also shown that the polytetrafluoroethylene ablation rate data of Kuper and Stuke obtained with 300 fs 248 nm laser pulses can also be described by the SSB model by modifying it to include the effects of nonlinear absorption.
Tumor hypoxia: Impact on gene amplification in glioblastoma (1992)

Gene amplification is frequently found in human glioblastoma but the mechanisms driving amplifications remain to be elucidated. Hypoxia as hallmark of glioblastoma is known to be involved in the induction of fragile sites that are central to gene amplification. We analyzed the potential of hypoxia (pO2 0%) and mini hypoxia (pO2 5%) to induce fragile sites within a homogeneously staining region (HSR) at 12q14-15 in a glioblastoma cell line (TX3868). Treatment of cells by hypoxia or by mini hypoxia induced double minutes (DMs) and caused breakage of the HSR structure at 12q14-15, suggesting a novel hypoxia inducible fragile site on 12q. Treatment with aphidicolin, a known fragile site inducer, indicates that the hypoxia inducible fragile site is a common fragile site. Reintegration of amplified sequences and occurrence of anaphase-bridge-like structures shows that mini hypoxia and hypoxia are able to initiate amplification processes in human glioblastoma cells. Hypoxia as known tumor microenvironment factor is crucial for the development of amplifications in glioblastoma. The identification and characterization of novel common fragile sites induced by hypoxia will improve the understanding of mechanisms underlying amplifications in glioblastoma.
Antimicrobial Oil-in-Water Nanoemulsions: Synergistic Effect of Nisin and Carvacrol against Bacillus subtilis (2016)

The aim of this study was to elucidate the mode of action of two antimicrobial compounds, nisin, which is hydrophilic, and the lipophilic compound carvacrol. For that purpose, both antimicrobials were loaded into Oil-in-/Water nanoemulsions, and their antimicrobial activity against Bacillus subtilis was investigated. The experimental results indicated that the O/W nanoemulsions loaded with both, nisin and carvacrol, having Sauter mean diameter (d 3,2 ) of around 120 nm, were considerably stable under the conditions investigated (up to 1 week storage at room temperature). The interfacial tension between nisin aqueous solutions and soybean oil could be reduced up to 12 mN/m, as compared to that of pure water and soybean oil (21 mN/m), so that demonstrating the potential of nisin to be used as emulsifier. The results obtained for O/W nanoemulsions loaded with both antimicrobial compounds indicated a reduction of nearly two log cycles (around 100 times) on B. subtilis population upon incubation for 24 h, compared to the blank (10 mM phosphate buffer).
THE PRODUCTION AND EVALUATION OF ANTIBODIES FOR ENZYME IMMUNOASSAY OF AZTTP (2001)

We describe the development of the first enzyme immunoassay for quantifying AZTTP that does not use of radioactive labeling. Anti-AZTTP antibodies were raised in rabbits by immunizing with an AZTTP-kelhoyle limpet hemocyanin (KLH) conjugate. Competitive immunoassays indicated a nanomolar sensitivity to AZTTP. One of the antisera produced was specific for AZTTP.
The Palomar Digital Sky Survey (DPOSS) (1998)

We describe DPOSS, a new digital survey of the northern sky, based on the POSS-II photographic sky atlas. The survey covers the entire sky north of delta = -3 deg in 3 bands, calibrated to the Gunn $gri$ system, reaching to equivalent limiting magnitude of B_lim ~ 22 mag. As a result of the state-of-the-art digitisation of the plates, detailed processing of the scans, and a very extensive CCD calibration program, the data quality exceedes that of the previous photographically-based efforts. The end product of the survey will be the Palomar-Norris Sky Catalog, anticipated to contain > 50 million galaxies and > 2 billion stars, down to the survey classification limit, ~ 1 mag above the flux detection limit. Numerous scientific projects utilising these data have been started, and we describe briefly some of them; they illustrate the scientific potential of the data, and serve as the scientific verification tests of the survey. Finally, we discuss some general issues posed by the advent of multi-terabyte data sets in astronomy.
High-Efficiency Heterojunction Photovoltaic Devices by Block Copolymer Nanotemplates (2005)

Ultra high density arrays of conducting poly(pyrrole) (Ppy) and poly (3-hexyl thiopene) (P3HT) nanowires with diameters of 10~25 nm were prepared on indium-tin oxide coated glasses (ITO) by electropolymerization of the monomers inside nanoporous templated prepared by block copolymers. These high density arrays of conducting polymer nanowires could be used as P-type materials for photovoltaic devices. It was observed that even after the PS matrix was removed, the free standing conducting polymer nanowires persisted without collapsing the wire onto the substrate. Such structures could not be achieved by the electropolymerization of a conducting polymer inside an anodized aluminum oxide (AAO) membrane, where the nanowires were found to fall onto the substrate after the AAO was removed. After removal of the PS matrix, the HOMO and LUMO levels of Ppy nanowires were measured to be ? 4.93eV and -3.69eV, respectively, which are slightly larger than the corresponding values (-4.79eV and -3.43eV) for Ppy thin films prepared by electropolymerization. Since the energy level of ITO glass is-4.8 eV, Ppy nanowires are more suitable for use as a P-type material. Due to the free standing geometry, a second N-type polymer can be easily spin-coated onto this array. Such arrays of polymer nanowires were also prepared on ITO-coated poly (ethylene terepthalate) film; demonstrating a new pathway to flexible photovoltaic devices.
Prototyping of Chitosan-Based Shape-Changing Structures (2019)

In the built environment, the typical means of achieving responsive changes in the physical features of a structure is through energy-intensive actuation mechanisms that contradict the intended goal of energy-efficient performance. Nature offers several alternative energy-free examples of achieving large-scale shape change through passive actuation mechanisms, such as the intrinsic response of water-absorbing (hygroscopic) materials to humidity fluctuations. We utilize this principle of passive actuation in the context of chitosan biopolymer, a material demonstrating a combination of mechanical strength and hygroscopic potential that enables it to serve for both load-bearing and actuation purposes. By inserting biocomposite films of chitosan as dynamic tensile members into a space truss, a structural system is constructed whose variable structural performance is manipulated and expressed as a large-scale, programmable, and fast-acting shape change. We present a method for rationalizing this responsive structural system as an assembly using a combination of materials engineering and digital design and fabrication. As a proof-of-concept, a two-meter-long fiber-reinforced cantilevering truss prototype was designed and fabricated. The truss transforms in minutes from one shape that shelters the interior from rain to another shape that acts as an air foil to increase ventilation.
Genetic lesions associated with blastic transformation of polycythemia vera and essential thrombocythemia (1997)

Polycythemia vera (PV) and essential thrombocythemia (ET) are chronic myeloproliferative disorders that may progress to acute leukemia in a subset of patients. This study aimed at investigating the genetic lesions associated with the blastic transformation of PV and ET. A panel of PV and ET cases at different stages of disease was analyzed for the presence of genetic alterations of TP53, NRAS, KRAS, and MDM2 by a combination of mutational analysis and Southern blot hybridization. The occurrence of microsatellite instability (MSI) was also tasted in selected cases. Samples of PV and ET analyzed in chronic phase disease were consistently devoid of all genetic lesions tested, suggesting that alterations of TP53, NRAS, KRAS, and MDM2 do not contribute significantly to development of chronic phase PV and ET. Conversely, mutations of TP53 were detected in 7/15 (46.6%) blastic phase cases, including 3/5 PV and 4/10 ET. In blastic phase patients for whom the corresponding chronic phase DNA was also available, it could be documented that the genetic lesion had arisen at the time of blastic transformation. In addition to TP53 mutations, cases of blastic phase PV and ET occasionally harbored mutations of NRAS (one case of blastic phase ET) or displayed MSI (one case of blastic phase PV). These data indicate that inactivation of TP53 is a relatively frequent event associated with the blastic transformation of PV and ET and may be responsible for the tumor progression of these disorders.
New reactions of 3-vinylindoles. II. Synthesis of 1,2-dimethyl-3-(2-indolylcarbonyl)piperidine (1973)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTNew reactions of 3-vinylindoles. II. Synthesis of 1,2-dimethyl-3-(2-indolylcarbonyl)piperidineGordon W. GribbleCite this: J. Org. Chem. 1973, 38, 23, 4074–4075Publication Date (Print):November 1, 1973Publication History Published online1 May 2002Published inissue 1 November 1973https://pubs.acs.org/doi/10.1021/jo00987a030https://doi.org/10.1021/jo00987a030research-articleACS PublicationsRequest reuse permissionsArticle Views77Altmetric-Citations7LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
A low-power 16-bit multiplier-accumulator using series-regulated mixed swing techniques (2002)

This paper describes an on-chip series-regulated mixed swing methodology with sleep-mode control for lowering the power consumption of high-performance DSP multiplier-accumulator (MAC) circuits. A 16*16+36-bit overlapped bit-pair Booth recoded Wallace tree MAC is fabricated in a commercial 0.5 /spl mu/m CMOS process in the proposed series-regulated methodology and conventional static CMOS. Up to 2.55/spl times/ reduction in energy/operation is measured over static CMOS, while offering a simultaneous 1.8/spl times/ improvement in low-voltage manufacturability. At the maximum clock frequency of 67 MHz, the proposed approach consumes a total MAC power of 16.6 mW in active mode and 152.5 nW in standby mode. Measured peak-peak power/ground bounce is under 8% of the regulated low-swing voltage. Experimental results from comparisons in three additional (0.35 /spl mu/m, 0.25 /spl mu/m, 0.16 /spl mu/m) CMOS and fully-depleted SOI processes are also presented to demonstrate improved savings over static CMOS with process scaling.
Vertical short-scale structures in the upper tropospheric and lower stratospheric temperature and ozone at la Réunion Island (20.8°S, 55.3°E) (2000)

International audience
Preparation and Properties of Zr-Bearing Sorption Materials Based on Coal Fly Ash Microspheres (2019)

The influence of hydrothermal conditions on synthesis of analcime and a composite material ZrO2- analcime as well as zirconomolybdate coverings with ion exchange properties was studied using narrow fractions of aluminosilicate microspheres with a high content of a glass phase (91-95 wt. %). The possibility to synthesize ZrO2-analcime composites of narrow particle size distributions with maximum of about 40 μm and 6 μm under hydrothermal treatment at 150 °С was demonstrated starting from microspheres with Si/Al=2.7 and applying different regimes of a reaction mixture agitation. A microsphere material of a “core-shell” type such as ZrMo2O7(OH)2(H2O)2@(SiO2-Al2O3)glass with the nanostructured covering was prepared. Sorption properties of the materials regarding Nd3+, Sr2+ and Cs+ were studied under equilibrium conditions by means of determination of sorption isotherms and their fitting by the Langmuir model. Sorption parameters were determined including distribution coefficients which reach the values of 104−105 mL/g
Course of preeclamptic glomerular injury after delivery (2008)

We evaluated the early postpartum recovery of glomerular function over 4 wk in 57 women with preeclampsia. We used physiological techniques to measure glomerular filtration rate (GFR), renal plasma flow, and oncotic pressure (pi(A)) and computed a value for the two-kidney ultrafiltration coefficient (K(f)). Compared with healthy, postpartum controls, GFR was depressed by 40% on postpartum day 1, but by only 19% and 8% in the second and fourth postpartum weeks, respectively. Hypofiltration was attributable solely to depression, at corresponding postpartum times, of K(f) by 55%, 30%, and 18%, respectively. Improvement in glomerular filtration capacity was accompanied by recovery of hypertension to near-normal levels and significant improvement in albuminuria. We conclude that the functional manifestations of the glomerular endothelial injury of preeclampsia largely resolve within the first postpartum month.
In vivo involvement of polymorphonuclear neutrophils in Leishmania infantum infection (2001)

Taken together these data show that neutrophil cells contribute to the early control of the parasite growth in spleen but not in liver and that these cells have no significant effect late in infection in either of these target organs.
Photoluminescence of silicon after deposition of polycrystalline diamond films (2009)

Low-temperature (5K) photoluminescence of silicon substrates in the range 0.8–1.2 eV is studied before and after deposition of polycrystalline diamond films. The diamond films were deposited in the microwave plasma onto high-purity dislocation-free silicon (with the resitivity ρ ≈ 3 kΩ cm) subjected to mechanical polishing or more delicate chemical and mechanical polishing. The deposition temperature was 750–850°C. In the photoluminescence spectra of the samples with the substrates polished chemically and mechanically, two lines, D 1 and D 2, corresponding to the dislocation-related emission are recorded. Generation of dislocations in the substrates is caused by efficient adhesion of the diamond film and, as a result, by internal stresses that relax with the formation of dislocations. The experimental spectra are practically identical to the photoluminescence spectra observed in silicon (ρ ≈ 100 Ω cm) with the density of dislocations ∼104 cm−2.
Cross-talk between the mitogen activated protein kinase and bone morphogenetic protein/hemojuvelin pathways is required for the induction of hepcidin by holotransferrin in primary mouse hepatocytes (2009)

We demonstrate that hepatocytes are liver iron-sensor cells and that transferrin receptor-2, by signaling through the ERK1/2 pathway, and bone morphogenetic protein/hemojuvelin, by signaling through the Smad pathways, coordinately regulate the iron-sensing machinery linking holotransferrin to hepcidin.
Efficient Crowdsourcing With Stochastic Production (2012)

A principal seeks production of a good within a limited time-frame with a hard deadline, after which any good procured has no value. There is inherent uncertainty in the production process, which in light of the deadline may warrant simultaneous production of multiple goods by multiple producers despite there being no marginal value for extra goods beyond the maximum quality good produced. This motivates a crowdsourcing model of procurement. We address efficient execution of such procurement from a social planner's perspective, taking account of and optimally balancing the value to the principal with the costs to producers (modeled as effort expenditure) while, crucially, contending with self-interest on the part of players. A solution to this problem involves both an algorithmic aspect that determines an optimal effort level for each producer given the principal's value, and also an incentive mechanism that achieves equilibrium implementation of the socially optimal policy despite the principal privately observing his value, producers privately observing their skill levels and effort expenditure, and acting only to maximize their own individual welfare. In contrast to popular winner take all contests, the efficient mechanism we propose involves a payment to every producer that expends non-zero effort in the efficient policy.
The First Rapid Palladium‐Catalyzed Aminations of (Azahetero)aryl Chlorides under Temperature‐Controlled Microwave Heating. (2004)

Abstract For Abstract see ChemInform Abstract in Full Text.
Gears and Gear Trains (2018)

This chapter discusses the kinematics of gears; that is, the motion relationships between gears. It explores how to conduct force and torque analysis on gears in order to calculate bearing loads and the like. Bevel gears transmit motion between non-parallel, intersecting shafts, in most cases the shafts are perpendicular to one another. The spiral shaped gear is called the "worm" and the gear it meshes with is called the "worm gear." The topic of gear train efficiency has been much studied in the past 100 years, and no simple, all-encompassing theory has emerged. Once a gear train has been selected and manufactured, laboratory testing must be carried out if an estimate of absolute efficiency is required. Thus, the methods presented here are approximate, and should only be used for the purpose of comparing one design with another.
OFDM MIMO radar for low-grazing angle tracking (2009)

We develop a low-grazing angle (LGA) tracking method considering realistic physical and statistical effects, such as earth's curvature, vertical refractivity gradient of standard lower atmosphere, and non-Gaussian characteristics of sea-clutter. We employ a co-located multiple-input-multiple-output (MIMO) radar configuration using wideband orthogonal frequency division multiplexing (OFDM) signalling scheme. Apart from the frequency diversity provided by OFDM, we also exploit polarization to resolve the multipath signals by using polarization-sensitive transceivers. Thus, we can track the scattering coefficients of the target at different frequencies along with its position and velocity. We apply a sequential Monte Carlo method (particle filter) to track the target. Our numerical examples demonstrate the achieved performance improvements due to realistic physical modeling and OFDM MIMO configuration.