gebhart/patrepeval huggingface dataset:
[Plasma cell leukemia associated with monocytosis]. (1997)

A 51-year-old man was admitted to our hospital in December 1993, because of fatigue. Peripheral blood tests showed a WBC of 49,400/microliter with 36% plasma cells and 35% monocytes, Hb 14.5 g/dl, and Plt 137,000/microliter. Bone marrow aspirate revealed hypercellularity with 48.7% plasma cells and 22.4% monocytes. Plasma cells in blood were positive for CD38 and PCA-1. Serum calcium, IgA and M-CSF levels were elevated to 14.1 mg/dl, 2,337 mg/dl and 2.7 ng/ml, respectively. Immunoelectrophoresis of serum and urine revealed IgA lambda type M protein and lambda type Bence Jones protein, respectively. Rearrangements of immunoglobulin heavy chain and light chain were demonstrated by Southern blotting analysis. Plasma cell leukemia (IgA lambda type) was diagnosed. He was treated with combination chemotherapy and IFN-alpha and achieved complete remission. However, he suffered a meningeal relapse in February 1995, and died in April 1996. It seems likely that the enhanced production of M-CSF by myeloma cells and/ or activated B cells stimulated monocyte production.
ChemInform Abstract: SYNTH. VON VERBINDUNGEN AUS DER PURIN‐REIHE 24. MITT. 8‐R‐METHYL‐DERIVATE VON 2,3,7‐TRIMETHYLHYPOXANTHIN (1972)

Abstract Durch Umsetzung von 8‐Chlortheobromin (I) mit Phosphoroxychlorid gelangt man in 60%iger Ausbeute zu 2,8‐Dichlortheobromin (II) und in geringem Maße zum Isomeren (III).
Oxidation of Metal−EDTA Complexes by TiO<sub>2</sub> Photocatalysis (1997)

Ethylenediaminetetraacetic acid (EDTA), a common industrial agent for complexing metal ions in water, frequently inhibits conventional metals-removal technologies used in water treatment. This study investigated the use of TiO2 photocatalysis for the aqueous-phase oxidation of EDTA and several metal complexes of EDTA. Reactions were performed at 0.1 wt % loading of Degussa P-25 TiO2, a solute concentration of 0.8 mM and at a constant pH. The different metal−EDTA complexes exhibited widely different photocatalytic oxidation rates under equivalent conditions of pH = 4 ± 0.1 in an aerobic system: Cu(II)−EDTA > Pb(II)−EDTA >> EDTA > Ni(II)−EDTA ≈ Cd(II)−EDTA ≈ Zn(II)−EDTA >>> Cr(III)−EDTA. Photoefficiency based on the Cu(II)−EDTA initial rate is nearly 60%. The rates of total organic carbon (TOC) removal and formaldehyde generation during photocatalytic EDTA oxidation indicate similarities to electrochemical oxidations of EDTA. Several means were explored to enhance the oxidation of Ni(II)−EDTA, whose behavior was taken to represent that of the slowly oxidizing complexes. Continuous addition of H2O2 solution during the photocatalytic treatment increased the oxidation rate for Ni(II)−EDTA as did the presence of homogeneous Cu2+. The presence of Cu2+ led to rapid ligand exchange transforming the Ni(II)−EDTA into Cu(II)−EDTA, which is easily oxidized.
Characterization of the Posttranscriptional Modifications in <i>Legionella pneumophila</i> Small‐Subunit Ribosomal RNA (2008)

It is generally accepted that posttranscriptional modifications in RNA play a role in the fine-tuning of RNA function and the maintenance of RNA structure. This article describes the characterization of the posttranscriptional modifications in Legionella pneumophila 16S rRNA by mass spectrometry and reverse transcriptase assays. Eight modified nucleotides were identified and mapped in the 16S rRNA sequence. Situation of these data in relation to general 16S rRNA modification patterns shows that L. pneumophila is relatively less modified, and that the majority of the L. pneumophila 16S rRNA modifications are conserved among the bacteria characterized so far (Escherichia coli, Clostridium acetobutylicum, Thermus thermophilus, and Thermotoga maritima).
Design of compact bandpass filter using transformer-based coupled resonators on integrated passive device glass substrate (2011)

This paper presents a transformer-based coupled resonator structure for a bandpass filter (BPF) using the integrated passive device technology on a glass substrate. The use of such a transformer-based coupled BPF not only provides the advantage of compact size but also creates extra transmission zeros to enhance the roll-off rate or the desired stopband rejection. The measured results verify the validity of this design methodology and show good agreement with the simulated results. For demonstration purposes, two example filters are designed and implemented. Both good performance and miniaturization are achieved for the proposed filters, and the expected transmission zeros are observed.
Evaluation, modification, and deployment of the ECOP-II computer program (1988)

This project, conducted at Oak Ridge National Laboratory (ORNL), covered the evaluation and modification of teh ECOP-II computer program. The project also included the development of recommendations on the deployment of ECOP-II. The ECOP-II computer program (Energy Conservation Opportunity Program for small commercial and light industrial buildings) was previously developed under direction of the U.S. Air Force. This report presents the results of data gathering efforts at 11 military installations, reviews of algorithms and calculations, the validation analysis of ECOP-II, and recommendations on general use of ECOP-II, personnel requirements, and related recommendations for energy management efforts at military bases. Some additional effort to correct remaining problems with ECOP-II is needed before considering the program ready for field use. Limited field use of the program can be started with the understanding that the results should still be checked to see if they make sense.
Familial Predisposition and Differences in Radiographic Patterns in Spontaneous Nonaneurysmal Subarachnoid Hemorrhage (2020)

We found a high rate of family history of intracranial aneurysms in patients who presented with naSAH. Although there was no difference in clinical outcome in patients with and without family history, there appears to be a higher percentage of nonperimesencephalic radiographic patterns of SAH in those with family history, suggesting possible different etiologies of these hemorrhages.
Notizen: Isomerism in the Linear Tetratertiary Phosphine 1,1,4,7,10,10-Hexaphenyl-1, 4,7,10-Tetraphosphadecane (1974)

Two isomers of the linear tetratertiary phosphine (C 6 H 5 ) 2 ΡCH 2 CH 2 Ρ(C 6 H 5 )CH 2 H 2 Ρ(C 6 H 5 )CH 2 CH 2 Ρ- (C 6 H 5 ) 2 with widely differing solubilities and melting points can be obtained from the base-catalyzed addition of C 6 H 5 P(H)CH 2 CH 2 P(H)C 6 H 5 to two equivalents of diphenylvinylphosphine; these appear to be the dl and meso diastereoisomers arising from the two equivalent asymmetric phosphorus atoms.
A Transmission-Cost-Based Model to Estimate the Amount of Market-Integrable Wind Resources (2012)

In the pursuit of the large-scale integration of wind power production, it is imperative to evaluate plausible frictions among the stochastic nature of wind generation, electricity markets, and the investments in transmission required to accommodate larger amounts of wind. If wind producers are made to share the expenses in transmission derived from their integration, they may see the doors of electricity markets closed for not being competitive enough. This paper presents a model to decide the amount of wind resources that are economically exploitable at a given location from a transmission-cost perspective. This model accounts for the uncertain character of wind by using a modeling framework based on stochastic optimization, simulates market barriers by means of a bi-level structure, and considers the financial risk of investments in transmission through the conditional value-at-risk. The major features of the proposed model, which is efficiently solved using Benders decomposition, are discussed through an illustrative example.
A Parametric Channel Model for Smart Antennas Incorporating Mobile Station Mobility (2006)

This paper presents a parameterized physical channel model for evaluating the performance of smart antenna systems. The channel model assumes a single antenna at the mobile station and a uniform linear array of omni-directional antenna elements at the base station. It incorporates parameters such as azimuth angle of arrival and departure, angle spread, power delay profiles and Doppler frequency, which have critical influence on the performance of smart antennas. A new feature of the channel model is a thorough framework for the incorporation of user mobility. The proposed model allows for efficient and accurate representation of smart antenna channel aspects, while maintaining low complexity for system level simulations
03 - Signal : un langage pour le traitement du signal (1983)

SIGNAL is a language (which definition is in progress at IRISA), intended to be the algorithms description language t?l a\nCAD system for real time signal processing applications . Main characteristics of SIGNAL are issued from data ,,flow\nprinciples : a program describes an oriented graph the nodes of which are processes (i . e . arithmetical and temporal primitiv e\nfunctions) connected through their input and output ports. SIGNAL is able to describe and run any real time algorithm .\nThe presentation is illustrated by the way of an adaptive gradient lattice algorithm, treated as an example .
ChemInform Abstract: Extreme Enantiomeric Discrimination of Fluoroalkanes Using Deuterium NMR in Chiral Liquid Crystalline Media. (2002)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Innovation au sens large. Une étude pour la mesure de l’innovation. (2004)

L’innovation est considérée en général comme l’un des facteurs les plus importants pour la compétitivité des entreprises et pour la stimulation de la croissance économique et de l’emploi. Il va de soi que la mise en oeuvre d’une politique d’innovation efficiente est basée sur l’identification des différents aspects des activités novatrices (allant de la recherche de nouvelles sources d’innovation, en passant par tous les obstacles pour aboutir enfin aux effets novateurs). L’innovation est toutefois un concept difficilement mesurable, qui est jusqu’à ce jour axé principalement sur l’innovation technologique dans l’industrie transformatrice. On sait dès lors très peu des outils pour mesurer l’innovation dans le secteur des services et de l’innovation sur le plan organisationnel. Ces activités remplissent dorénavant un rôle plus prononcé dans la vie économique et ne peuvent donc être négligées plus longtemps. L’enquête la plus importante concernant l’innovation à l’échelle internationale, à savoir l’enquête d’Innovation européenne apporte très peu d’éléments nouveaux. La demande d’outils plus adéquats pour mesurer l’innovation qui émane tant des milieux politiques (européens, nationaux ou locaux) que des milieux de la recherche et du monde industriel est dès lors pertinente. C’est la raison pour laquelle, la Politique scientifique fédérale a chargé l’ULB et HIVA d’effectuer une étude, en collaboration avec l’Autorité fédérale – dans le cadre des “actions transversales2” – pour développer des outils de mesure de l’innovation au sens large, en mettant l’accent sur les innovations dans le secteur des services et l’innovation sur le plan organisationnel. Le rapport qui vous est proposé, a été présenté aussi dans le cadre de la révision du manuel d’Oslo (la référence internationale pour mesurer l’innovation) et a pour objectif de donner une nouvelle impulsion à la recherche de meilleures statistiques d’innovation et par la même occasion d’aboutir à une politique d’innovation plus efficace à tous les niveaux (local, national, européen).
High-resolution imaging of the human retina with a Fourier deconvolution technique (2002)

A high-resolution retinal imaging camera is described that uses a Shack-Hartmann wave-front sensor and a Fourier deconvolution imaging technique. The operation of the camera is discussed in detail and high-resolution retinal images of the human cone mosaic are shown for a retinal patch approximately 10 arc min in diameter from two different retinal locations. The center-to-center cone spacing is shown to be approximately 2.5 microm for the retinal images recorded at 2 degrees temporal from the central fovea and approximately 4 microm for the retinal images recorded at 3 degrees temporal from the central fovea.
ChemInform Abstract: Enantioselective Syntheses of 1‐O‐Benzyl‐sn‐glycerol and 1‐O‐Hexadecyl‐ 2‐O‐methyl‐sn‐glycerol via Asymmetric Dihydroxylation of Allyl 4‐ Methoxyphenyl Ether. Use of AD‐Mix Supplemented with Potassium Persulfate. (1994)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Calcium-induced tertiary structure modifications of endo-β-1,3-glucanase from <i>Pyrococcus furiosus</i> in 7.9 M guanidinium chloride (2005)

The family 16 endo-beta-1,3 glucanase from the extremophilic archaeon Pyrococcus furiosus is a laminarinase, which in 7.9 M GdmCl (guanidinium chloride) maintains a significant amount of tertiary structure without any change of secondary structure. The addition of calcium to the enzyme in 7.9 M GdmCl causes significant changes to the near-UV CD and fluorescence spectra, suggesting a notable increase in the tertiary structure which leads to a state comparable, but not identical, to the native state. The capability to interact with calcium in 7.9 M GdmCl with a consistent recovery of native tertiary structure is a unique property of this extremely stable endo-beta-1,3 glucanase. The effect of calcium on the thermodynamic parameters relative to the GdmCl-induced equilibrium unfolding has been analysed by CD and fluorescence spectroscopy. The interaction of calcium with the native form of the enzyme is studied by Fourier-transform infrared spectroscopy in the absorption region of carboxylate groups and by titration in the presence of a chromophoric chelator. A homology-based model of the enzyme is generated and used to predict the putative binding site(s) for calcium and the structural interactions potentially responsible for the unusual stability of this protein, in comparison with other family 16 glycoside hydrolases.
[Schizophrenia and ocular misalignment: phenotypic and genetic association analysis]. (2004)

The increased incidence of minor physical anomalies (MPAs) in schizophrenia is the fundamental basis for the neurodevelopmental hypothesis of schizophrenia etiology. Ocular misalignment falls into the category of MPAs, but this phenotype has not been assessed in schizophrenia. This study reveals that constant exotropia displays marked association with schizophrenia. To assess the genetic mechanisms, we examined the transcription factor genes ARIX and its paralogue, PMX2B. We identified frequent deletion/insertion polymorphisms in the 20-alanine homopolymer stretch of PMX2B, with a modest association between these functional polymorphisms and constant exotropia in schizophrenia. The polymorphisms were also associated with overall schizophrenia and more specifically with schizophrenia manifesting strabismus. These results suggest a possible interaction between PMX2B and other schizophrenia-precipitating factors, increasing the risk of the combined phenotypes. This study also highlights the unique nature of the polyalanine length variations found in PMX2B.
High-Throughput Amplicon Sequencing Reveals Distinct Communities within a Corroding Concrete Sewer System (2012)

Microbially induced concrete corrosion (MICC) is an important problem in sewers. Here, small-subunit (SSU) rRNA gene amplicon pyrosequencing was used to characterize MICC communities. Microbial community composition differed between wall- and ceiling-associated MICC layers. Acidithiobacillus spp. were present at low abundances, and the communities were dominated by other sulfur-oxidizing-associated lineages.
Enantiodivergent synthesis of (+)- and (-)-anatoxin from L-glutamic acid (1990)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTEnantiodivergent synthesis of (+)- and (-)-anatoxin from L-glutamic acidF. Javier Sardina, Michael H. Howard, Marshall Morningstar, and Henry RapoportCite this: J. Org. Chem. 1990, 55, 17, 5025–5033Publication Date (Print):August 1, 1990Publication History Published online1 May 2002Published inissue 1 August 1990https://pubs.acs.org/doi/10.1021/jo00304a012https://doi.org/10.1021/jo00304a012research-articleACS PublicationsRequest reuse permissionsArticle Views419Altmetric-Citations51LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Peptidase allergen Der p 1 initiates apoptosis of epithelial cells independently of tight junction proteolysis (2003)

Loss of epithelial cell polarity, which can arise following disruption of tight junctions (TJs), is a precursor to the care-fully orchestrated removal of moribund cells from epithelia in apoptosis. Ordinarily, this cycle of events has minimally disruptive effects on the function of the epithelial barrier, but some agents have been identified that induce apoptosis and promote epithelial leakiness. The allergen Der p 1 is a cysteine peptidase that cleaves TJ adhesion proteins and induces apoptosis in epithelial cells. This suggests the possibility that, at least for some inducers of apoptosis, these events might be causally linked. We report here that Der p 1 induces epithelial apoptosis before outright cell detachment and that apoptosis occurs within the same time span as increased paracellular permeability in polarized epithelial monolayers. Whilst TJ-deficient BEAS-2B cells were resistant to Der p 1-induced apoptosis, the cell line 1HAEo-, which was also TJ deficient, was sensitive to Der p 1, providing evidence against TJ proteolysis as a cause of apoptosis. To provide direct evidence, we propagated cells that normally express TJs in low calcium medium that prevented intercellular junction assembly. These cells retained full susceptibility to Der p 1, indicating that Der p 1-induced apoptosis is independent from TJ proteolysis.
Long-Term Exposure to Air Pollution and Markers of Inflammation, Coagulation and Endothelial Activation: a Repeat Measures Analysis in the Multi-Ethnic Study of Atherosclerosis (MESA) (2014)

Air pollution is associated with cardiovascular disease (CVD) and systemic inflammation is posited to mediate this effect. Animal, experimental and epidemiologic studies suggest increases in short-term air pollution cause an inflammatory response. Much of the past literature has focused on the association between short-term air pollution exposure and markers of inflammation and coagulation. We assessed both the association between long- and short-term exposure to air pollution and markers of inflammation, coagulation and endothelial activation. We studied participants from the Multi-Ethnic Study of Atherosclerosis (MESA) with repeat measures of serum C-reactive protein (CRP), interleukin-6 (IL-6), fibrinogen, D-dimer, soluble E-selectin and soluble Intercellular Adhesion Molecule-1 (sICAM-1). We estimated associations of these markers with long-term ambient fine particulate matter (PM2.5), individual-level ambient PM2.5 (integrating indoor concentrations and time-location data), oxides of nitrogen (NOX), nitrogen dioxide (NO) and black carbon averaged over the year prior to blood draw. Short-term concentrations of PM2.5 reflected day of blood draw, prior day, and moving average of prior 2, 3, 4, and 5 day periods. CRP, IL-6 and D-Dimer were log-transformed. A random effects model was used to account for within-person clustering. After controlling for confounders, a 5 µg/m3 increase in long-term ambient PM2.5 was associated with a 5.53% higher IL-6 level (95% CI: 1.83, 9.36) and a 40 ppb increase in long-term NOx was associated with 7.07% higher level in D-dimer (95% CI: 1.62, 12.83). CRP, E-selectin and sICAM-1 showed little association with long-term air pollution and associations between short-term ambient PM2.5 and blood markers was largely null. These data are consistent with the hypothesis that associations between long-term exposure to air pollution are related to inflammation and fibrinolysis.
Perspectives of SiC Power Devices in Highly Efficient Renewable Energy Conversion Systems (2009)

In the long run, regenerative energy sources represent the most important alternatives to fossil fuels. In general, they are characterized by decentralized logistics and supply capabilities due to ihnerent lower energetic densitiy per are, when compared with the fossil counterparts. As a result, the increased use of regenerative energy sources will require decentralized structures for energy supply, consumption optimisation and regional balancing between supply and demand. Both, the more efficient utilization of fossil energy sources and the utilization of regenerative energy sources, lead to increasingly decentralized supply structures and can be understood as being both complementary and convergent in relation to each other. Most of the converter units for utilization of decentralized energy resources (DER) use power electronics for the AC power conditioning with grid quality. The current paper shows market perspectives of DER applications and the impact of SiC on these application.
Traffic Safety Basic Facts 2012 : Children (2013)

The CARE database brings together the disaggregate details of road accidents and casualties across Europe, by combining the national accident databases that are maintained by all EU member states. Access to the CARE database is restricted, however, so it is important that a comprehensive range of publications based on these data be accessible to the general public. This process was begun in the SafetyNet project that was carried out between 2004 and 2008, and the concept of the Basic Fact Sheet (BFS) Basic Fact Sheets and Annual Statistical Report (ASR) was developed. By 2008, twelve Fact Sheets were being prepared annually by researchers at five institutes. This Fact Sheet presents an overview highlighting the main facts for Children. Wherever possible, measures of risk are calculated by relating the number of fatalities from CARE to exposure data available from other sources. Most Fact Sheets examined trends over the period 2001-2010, with more detailed analyses of data from 2010.