gebhart/patrepeval huggingface dataset:
Fatigue of Materials (1998)

Written by a leading researcher in the field, this revised and updated second edition of a highly successful book provides an authoritative, comprehensive and unified treatment of the mechanics and micromechanisms of fatigue in metals, non-metals and composites. The author discusses the principles of cyclic deformation, crack initiation and crack growth by fatigue, covering both microscopic and continuum aspects. The book begins with discussions of cyclic deformation and fatigue crack initiation in monocrystalline and polycrystalline ductile alloys as well as in brittle and semi-/non-crystalline solids. Total life and damage-tolerant approaches are then introduced in metals, non-metals and composites followed by more advanced topics. The book includes an extensive bibliography and a problem set for each chapter, together with worked-out example problems and case studies. This will be an important reference for anyone studying fracture and fatigue in materials science and engineering, mechanical, civil, nuclear and aerospace engineering, and biomechanics.
Alpha 1- and alpha 2-adrenoceptor selectivity of moxisylyte (thymoxamine) and its metabolites in the pithed rat. (1983)

The selectivity of moxisylyte and its two metabolites deacetylmoxisylyte and demethyldeacetylmoxisylyte, for alpha 1- and alpha 2-adrenoceptors has been investigated in the pithed rat. Alpha 2-adrenoceptor blockade was measured by antagonism of the inhibitory effect of clonidine on the tachycardia produced by electrical stimulation of the cardiac accelerator nerves and of the pressor response to B-HT 933. alpha 1-Adrenoceptor blockade was measured by inhibition of the pressor response to (-)phenylephrine and to stimulation of the sympathetic outflow from the spinal cord. The three drugs (5 X 10(-6) to 2 X 10(-5) mol/kg i.v.) did not affect the inhibitory effect of clonidine and were equipotent as antagonists of the pressor response to B-HT 933, but only at the higher dose (10(-5) mol/kg). Moxisylyte and its metabolites (2.5 X 10(-6) to 10(-5) mol/kg i.v.) reduced the pressor response to (-)phenylephrine and to stimulation of the sympathetic outflow of the spinal cord in a dose-dependent manner. They were much more effective against (-)phenylephrine than B-HT 933. These results indicate that the three drugs are preferential alpha 1-adrenoceptor antagonists in vivo.
Beam splitter layer emission in Fourier-transform infrared interferometers (1998)

The self-emission from the splitting layer of a Fourier-transform infrared interferometer is modeled with basic properties of optical thin films. The resulting equation gives explicitly the self-emission contribution in terms of the temperature, the complex refractive index, the reflection coefficient, and the thickness of the beam splitter layer.
CO<sub>2</sub> Cycloaddition Reactions Catalyzed by an Ionic Liquid Grafted onto a Highly Cross‐Linked Polymer Matrix (2007)

A support group for ionic liquids: 3-Butyl-1-vinylimidazolium chloride supported covalently on a polymer cross-linked with divinylbenzene gives rise to a very active, stable, and selective heterogeneous catalyst 1 for the addition of CO2 to epoxides (see scheme). Moreover, the catalyst can be easily separated from the products and reused.
Digital-item-based media management system and applications (2003)

This paper presents a new system architecture for managing multimedia content based on the digital item concept defined by MPEG-21. The focus is to provide a common interface such that: (1) media resources and metadata can be bound together and accessed seamlessly via a single platform-independent abstraction; (2) arbitrary, heterogeneous metadata formats can be used; and (3) content can be reliably exchanged and shared across different platforms. We demonstrate the effectiveness of such a system via two real-world applications: a media server product and a digital match management system for sports content.
Cancer‐Cell Targeting and Photoacoustic Therapy Using Carbon Nanotubes as “Bomb” Agents (2009)

A unique approach using the large photoacoustic effect of single-walled carbon nanotubes (SWNTs) for targeting and selective destruction of cancer cells is demonstrated. SWNTs exhibit a large photoacoustic effect in suspension under the irradiation of a 1064-nm Q-switched millisecond pulsed laser and trigger a firecracker-like explosion at the nanoscale. By using such an explosion, a photoacoustic agent is developed by functionalizing the SWNTs with folate acid (FA) that can selectively bind to cancer cells overexpressing folate receptor on the surface of the cell membrane and kill them through SWNT explosion inside the cells under the excitation of millisecond pulsed laser. The uptake pathway of folate-conjugated SWNTs into cancer cells is investigated via fluorescence imaging and it is found that the FA-SWNTs can enter into cancer cells selectively with a high targeting capability of 17-28. Under the treatment of 1064-nm millisecond pulsed laser, 85% of cancer cells with SWNT uptake die within 20 s, while 90% of the normal cells remain alive due to the lack of SWNTs inside cells. Temperature changes during laser treatment are monitored and no temperature increases of more than +/- 3 degrees C are observed. With this approach, the laser power used for cancer killing is reduced 150-1500 times and the therapy efficiency is improved. The death mechanism of cancer cells caused by the photoacoustic explosion of SWNTs is also studied and discussed in detail. These discoveries provide a new way to use the photoacoustic properties of SWNTs for therapeutic applications.
Alternating current susceptibility, high field magnetization, and millimeter band EPR evidence for a ground S = 10 state in [Mn12O12(Ch3COO)16(H2O)4].2CH3COOH.4H2O (1991)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAlternating current susceptibility, high field magnetization, and millimeter band EPR evidence for a ground S = 10 state in [Mn12O12(Ch3COO)16(H2O)4].2CH3COOH.4H2OAndrea Caneschi, Dante Gatteschi, Roberta Sessoli, Anne Laure Barra, Louis Claude Brunel, and Maurice GuillotCite this: J. Am. Chem. Soc. 1991, 113, 15, 5873–5874Publication Date (Print):July 1, 1991Publication History Published online1 May 2002Published inissue 1 July 1991https://pubs.acs.org/doi/10.1021/ja00015a057https://doi.org/10.1021/ja00015a057research-articleACS PublicationsRequest reuse permissionsArticle Views4288Altmetric-Citations884LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
EO and SAR Constellation Imagery Collection Planning (2014)

y its very nature, the satellite imagery collection planning challenge is difficult. The solution space is extremely large – encompassing thousands of imaging orders and hundreds of variables related to the abilities of the satellites, sensors, and ground network. The complex system constraints include power, data storage, pointing, agility, sensors, etc. Yet there is a desire for “optimized” plans that maximize return from limited and expensive resources while balancing objectives for priority, area collected, resolution, cloud cover, and more. Satellite imagery collection planning systems must meet the performance demands of multiple planning sessions to cover constellations of spacecraft for 15 orbits per day for a typical LEO spacecraft while meeting the short timelines intrinsic to dynamic cloud forecasts and customer requirements for fast order turnaround. Whether the satellite is a fully agile optical imager, fixed beam SAR spacecraft, pushbroom imager with limited agility, or a frame camera, Orbit Logic's Collection Planning & Analysis Workstation (CPAW) software solves the difficult problem of satellite imagery collection planning through a spacecraft simulator coupled with scheduling algorithms that generate high fidelity imagery collection plans for use in operations, analysis, or imagery ordering. CPAW covers everything from contact scheduling and recorder management to power and antenna modeling while accounting for clouds, terrain, timing constraints, platform agility, and sensor capabilities. Planning can be completely manual, fully automated, or anywhere in between to plan for anything from a single image on a single satellite to massive order decks collected by a mixed constellation of multiple EO and SAR spacecraft. Orbit Logic's CPAW software is currently the only commercial software package that can generate coordinated imagery collection plans for fully agile, fixed beam, frame camera, and pushbroom satellites in a single integrated system. This multi-use capability is especially useful in a fleet with a variety of assets or for imagery customers that have access to multiple spacecraft from multiple operators. The synergy and efficiency of using a single planning system instead of separate, stovepipe systems for each type of satellite can bring significant efficiency and value to satellite operators, analysts, and imagery end customers. The addition of satellites into CPAW is a quick and easy configuration process that does not generally require any new software development. The US Army Remote Ground Terminals (RGT) will be using CPAW to plan
Magnetic Storage Handbook (1996)

Table of contents
Introduction.Data Storage on Rigid Disks.Data Storage on Flexible Disks.Data Storage on Tape.Analog Video Recording.Digital Video Recording.Analog Audio Recording.Digital Audio Recording.Instrumentation Recording.Signal and Error-Control Coding.
Study of ghost peaks resulting from space charge and non-linear fields in an ion trap mass spectrometer (1998)

Ion trap improvements require some geometrical modifications which can alter significantly the relative linear and non-linear field contributions. In this work, where the ion trap was interfaced with an electrospray source, it was shown that under particular ion trapping conditions due to space charge, artefacts called ghost peaks are displayed in the mass spectra. They are characterized by particular width and shape and appear at twice the m/z ratio of the expected peaks (for positive and negative ions) when the analyzed ions are ejected at βz=1/3 (extended mass range mode). They were unambiguously identified by using isolation sequences. The various experimental factors governing the observation of ghost peaks were explored in order to rationalize their origin. Especially the capillary exit voltage, ion accumulation time and low m/z cut-off of the analytical scan, which modify the space charge strength, influence the ghost peak intensities. Furthermore, it is evidenced that only the injected ions which are located at qz⩽0.25 (βz⩽2/11) at the beginning of the analytical scan step give rise to the formation of such artefact peaks. Under these experimental conditions, the ion cloud defocused by space charge is subjected to high-order multipole fields (e.g. 22-pole). Then the motion of the analyzed ions is destabilized, affecting the ion ejection. It seems that two ion populations can co-exist: (i) one submitted to a normal ion ejection at qz=0.45, where the axial modulation is applied, i.e. normal peaks, and (ii) a second ejected at the natural qz=0.908 boundary, leading to ghost peaks at twice the m/z value of normal signals. © 1998 John Wiley & Sons, Ltd.
Epoxides in Titanocene‐Mediated and ‐Catalyzed Radical Reactions (2012)

Abstract Epoxides are among the most useful functional groups in organic chemistry. They are also excellent radical precursors. Ring opening can be achieved via electron transfer from low valent metal complexes. As yet, titanocene(III) chlorides have emerged as the most useful reagents in this respect. Catalytic reaction conditions have been described that exploit the stability of radicals under protic conditions. The use of enantiomerically pure titanocenes has resulted in a number of applications in enantioselective catalysis. Most recently, this has been demonstrated in enantioselective cyclizations. Other unexpected developments have been reported in the field of hydrogen atom transfer reagents for the reduction of radicals generated from epoxides. Titanocene bound water acts as an excellent hydrogen atom transfer (HAT) reagent. Moreover, H 2 can be employed as terminal reductant when activated by “hydrogenation” catalysts, such as RhCl(PPh 3 ) 3 . The most common application of the titanocene‐mediated or ‐catalyzed epoxide opening is in cyclization reactions. It has been demonstrated that cyclopropanes, cyclobutanes, cyclopentanes, cyclohexanes, and cycloheptanes are readily accessible. It is expected that these cyclizations will be increasingly frequently applied in the synthesis of natural products.
Correlation Statistics Distribution Convolution(CSDC)Modeling for Studying CDMA Indoor Wireless Systems with RAKE Receiver, Power Control & Multipath Fading (1996)

IEICE Transactions on Communications
Portrait of a Lady: A Recollection of Whistler (1966)

One of my occasional pleasures, as an historian living in Boston, is to visit with a very elderly, and very charming lady. Her acquaintance has included literary and artistic figures well known historically but not ordinarily thought of as being any longer within the reach of recollection. Being as modest as she is remarkable, these connections only emerge in the course of conversation. Once when we were discussing my preparations for a trip to Europe, she was pleased at the time I was allowing for Mont-Saint Michel, and inquired whether I might have read a book her “uncle Henry” had written on the subject. So it was another time, about three years ago, when I asked about a darkened oil portrait in the quiet and elegant dining room where we were having tea, and was told that the subject was herself and the painter was James McNeill Whistler. Recovering from my surprise, I asked for details and was given the following account of the episode.
Altiero Spinelli, Founder of the Movement for European Unity (2007)

Acute renal failure (ARF) is a common complication in hospitalized patients, but little is known about the epidemiology of ARF in China. In this study, we performed a prospective examination of the cause, prognosis, and risk factors associated with ARF at a hospital in Shanghai, China. We considered all ARF patients who were admitted to our hospital from December 2003 to December 2006. Among the 320 ARF patients, 135 (42.2%) were over the age of 60. Sepsis, heart failure, and nephrotoxic drug use were the leading causes of ARF. The overall mortality rate was 31.9%, and mortality rate was significantly higher among the elderly. Logistic regression indicated that heart failure, respiratory failure, and malignant cancer were risk factors independently associated with poor prognosis. In this Shanghai hospital, there was a high incidence and mortality rate of patients hospitalized with ARF. The prognosis of patients who underwent renal replacement therapy was better than those who were treated more conservatively.
Relationship between plasma norepinephrine and sympathetic neural activity. (1983)

For circulating norepinephrine (NE) to reflect sympathetic activity validly, plasma NE should show an intensity-dependent increase during sympathetic stimulation and decrease during sympathetic inhibition, and circulating NE should correlate with more directly obtained measures of sympathetic activity. Review of published evidence indicates that NE in peripheral plasma satisfies these criteria. However, models used to explain the relationship between circulating NE and sympathetic activity must take into account processes intervening between the synaptic cleft and free NE in the circulation and, since sympathetic outflow is regionalized, the contributions of specific vascular beds to circulating NE. In this report a model is presented where removal processes for NE are viewed as acting in series to produce a gradient in NE concentrations from synapse to plasma, and where the relative contributions of specific vascular beds are calculated from the arteriovenous difference in plasma NE across those beds and the percentage of cardiac output distributed to them. In general, venous plasma NE provides a useful estimation of average sympathetic outflow.
Dietary Practices and Beliefs in Patients with Inflammatory Bowel Disease (2015)

Our study showed that patients hold beliefs pertaining to the role of diet in IBD, with a high level of consistency around key perceived triggers. Whether all the symptoms reported are due to active inflammation cannot be ascertained, but the potential exists for dietary components triggering active disease and perpetuating gut injury, impacting on quality of life and health care costs.
Label-free separation and sorting of human monocytes and T-cells by electrowetting and dielectrophoresis (2013)

We report a label-free separation and sorting approach based on electrowetting-on-dielectric (EWOD) and dielectrophoresis (DEP) to manipulate human monocyte (THP-1) and T-cell (Jurkat) lines in droplets without any impact on cell viability. In addition to separating cells, this device provides a platform to study cell-cell interactions and migration before the separation.
Joint Adaptive Soft Frequency Reuse and Virtual Cell Power Control in Relay Enhanced Cellular System (2009)

This paper proposed a joint adaptive soft frequency reuse and virtual cell power control (JAP) algorithm for relay enhanced cellular (REC) system in LTE-A. The JAP algorithm allocates bandwidth to base station and relay node adaptively according to user distribution and target data rate and achieves frequency reuse factor be one among sectors. Furthermore, the JAP algorithm controls transmit power based on SIR-balance principle and adjusts power in "virtual cell", which can greatly mitigate co-channel interference among sectors. Simulation results show that the proposed algorithm can obtain both high average spectral efficiency and edge user throughput.
El vocabulario latino sobre la alimentación en la Antigüedad Tardía : de <i>Anthimus</i> a Isidoro de Sevilla (2019)

In this study some terms related to food in Late Antiquity are analysed in two works of very different type, Anthimus’ De obseruatione ciborum epistula and the Etymologies of Isidore of Seville, comparing the latter with some terms present on Visigothic slates. The objective of the analysis is to show the survival of a classical vocabulary and its possible evolution in later times, as elements to take into account for the construction of a possible Latin lexicon on food.
Antioxidant Effects and Mechanisms of Medicinal Plants and Their Bioactive Compounds for the Prevention and Treatment of Type 2 Diabetes: An Updated Review (2020)

Diabetes mellitus is a metabolic disorder that majorly affects the endocrine gland, and it is symbolized by hyperglycemia and glucose intolerance owing to deficient insulin secretory responses and beta cell dysfunction. This ailment affects as many as 451 million people worldwide, and it is also one of the leading causes of death. In spite of the immense advances made in the development of orthodox antidiabetic drugs, these drugs are often considered not successful for the management and treatment of T2DM due to the myriad side effects associated with them. Thus, the exploration of medicinal herbs and natural products as therapeutic sources for the treatment of T2DM is promoted because they have little or no side effects. Bioactive molecules isolated from natural sources have been proven to lower blood glucose levels <i>via</i> regulating one or more of the following mechanisms: improvement of beta cell function, insulin resistance, glucose (re)absorption, and glucagon-like peptide-1 homeostasis. In recent times, the mechanisms of action of different bioactive molecules with antidiabetic properties and phytochemistry are gaining a lot of attention in the area of drug discovery. This review article presents an update of the findings from clinical research into medicinal plant therapy for T2DM.
Side effect profiles of new antipsychotic agents. (1996)

Although neuroleptic drugs have become the mainstay of treating acute and chronic psychosis, they are substantially limited by troublesome side effects. The traditional neuroleptic drugs have a wide array of central nervous system and peripheral system side effects that often lead to problems in management or patient noncompliance. Of particular difficulty are the extrapyramidal symptoms and tardive dyskinesia. However, other side effects of seizures, sedation, neuroleptic malignant syndrome and cardiovascular, hematologic, endocrinological, and weight gain problems remain as clinical management challenges posed by existing antipsychotic drug therapy. Considerable progress has been made in improving the motor side effect profile with the advent of clozapine and risperidone. However, each of these drugs has its own dose-limiting side effect profile. Two new drugs, olanzapine and sertindole, are now added to the pharmacopeia for treating psychosis. They further improve the benefit/ risk ratio because they have even fewer EPS and other side effects. Overall, these new antipsychotic agents greatly improve the treatment of psychosis by reducing drug-induced morbidity and improving the quality of life for patients.
Anticandidal activity of bioinspired ZnO NPs: effect on growth, cell morphology and key virulence attributes of <i>Candida</i> species (2018)

The pathogenicity of Candida species in human is dependent on a variety of virulence factor such as adhesion factors, germ tube and hyphal formation, secretion of hydrolytic phospholipases and proteinases and drug resistance biofilm. ZnO NPs have been synthesized by using leaf extract of Crinum latifolium and were characterized by UV-Vis spectrophotometer, FTIR, SEM, EDX and TEM. In this study for the first time, potent inhibitory effects of ZnO NPs on principal virulence factors of Candida albicans and non-albicans such as germ tube formation, secretion of hydrolytic phospholipases and proteinases and biofilm formation has been investigated. ZnO NPs remarkably reduced the germ tube formation of C. albicans at 1 (86.4%), 0.5 (75.0%), 0.25 (61.4%), 0.125 (34.1%) and 0.062 mg/ml (11.4%). ZnO NPs significantly lowered the phospholipase and proteinase secretion by 58.8 and 95.2% at 0.25 mg/ml, respectively. CSLM results showed that ZnO NPs suppressed biofilm formation up to 85% at 0.25 mg/ml. SEM and TEM micrograph showed that ZnO NPs penetrated inside the cell and causes extensive damaged in cell wall and cell membrane. Inhibition of Candida growth and various virulent factors by ZnO NPs provides an insight towards their therapeutic application for the treatment of Candida-associated infections.
Diagnostic and Prognostic Value of the Cerebrospinal Fluid Concentration of Immunoglobulin Free Light Chains in Clinically Isolated Syndrome with Conversion to Multiple Sclerosis (2015)

The concentration of CSF FLC predicts conversion to MS within 2 years following CIS. OCB-positive patients with an early conversion have a higher concentration of CSF-FLC. We have also shown a prognostic significance of k-FLCCSF for future EDSS-progression.