gebhart/patrepeval huggingface dataset:
High‐dose cytosine arabinoside and mitoxantrone in previously‐treated acute leukemia patients (1990)

35 patients with refractory or relapsed acute leukemia received salvage chemotherapy using high-dose cytosine arabinoside 2 g/m2 intravenously for 3 hours every 12 h, in 8 doses, followed by continuous infusion of mitoxantrone 12 mg/m2/day for 2 d. 9 patients had acute myeloblastic leukemia (AML), (4 relapsed, 5 refractory), 20 had acute lymphoblastic leukemia (ALL) (11 relapsed, 9 refractory) and 6 had chronic myelogenous leukemia (CML) in the blastic phase (BP). 4 out of 9 AML and 16 out of 20 ALL achieved complete remission. Median survival was 6 months for all patients and 10 months for responders. A short (1.5 months) chronic phase was achieved in 3 patients with CML. The main toxic effect was hematologic. A pharmacokinetic study was performed on mitoxantrone. No correlation was found with clinical response. The combination of mitoxantrone and ara-C is an effective antileukemic regimen, especially in ALL.
Primary spinal epidural manifestation of malignant lymphoma (1996)

The clinical, histological and immunomorphological data in 19 cases of primary spinal epidural manifestation of malignant lymphomas collected between 1974 and 1994 are reported. The age of the patients varied between 11 and 87 years with a mean age of 56.3 years. There was a slight male predominance (11:8). In most cases, the onset of the clinical symptoms was rapid. The preferential tumour localization was the epidural space related to the thoracal vertebral bone. In each case, decompressive laminectomy was performed. The tumours were histologically and immunomorphologically classified as B-cell lymphomas (14 of 19), T-cell lymphomas (3 of 19) and anaplastic plasmacytoma (1 of 19). Except for one case, post-operative staging did not reveal anything other than epidural manifestation of the malignant lymphoma. The vertebral bone, however, was involved in seven cases. Irradiation alone, or in combination with chemotherapy, was performed as additional therapy. The post-operative survival time was variable.
Double-layered thin collector in n-type metal-base organic transistors (2013)

A very short channel length was achieved in vertical-type metal-base organic transistors using a double-layered collector composed of N , N ′-dimethyl-3,4,9,10-perylene tetracarboxylic diimide (Me-PTC) and N , N ′-distearyl-3,4,9,10-perylene tetracarboxylic diimide (St-PTC). St-PTC showed low electric conductivities, but inserting it at the interface with the collector electrode improved the on/off ratio to 4 × 10 4 for a total collector thickness of 105 nm. The decrease in the off current was attributed to the low electric conductivity of St-PTC, and the increase in the on current was discussed from the viewpoint of the morphological change of the collector layer.
Identification of the colony-stimulating cell in human peripheral blood (1972)

Bone marrow colony formation in soft gel culture may be stimulated by substances elaborated by human peripheral blood leukocytes. In order to determine the cell type responsible for colony stimulation, peripheral leukocytes were separated by Ficoll-Hypaque gradients and differential glass adhesion. Morphologic, histochemical, and functional criteria were applied to determine the purity of the monocyte, lymphocyte, and neutrophil fractions. Using these cells as feeder layers and as a source of conditioned medium, evidence was obtained that the monocyte is the colony-stimulating cell of human peripheral blood. Activity greater than that of mixed white cells was obtained with monocyte underlayers, and only monocyte- and macrophage-conditioned media were shown to have significant colony-stimulating activity.
Pyrolysis of Polytetrafluoroethylene (1947)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPyrolysis of PolytetrafluoroethyleneE. E. Lewis and M. A. NaylorCite this: J. Am. Chem. Soc. 1947, 69, 8, 1968–1970Publication Date (Print):August 1, 1947Publication History Published online1 May 2002Published inissue 1 August 1947https://pubs.acs.org/doi/10.1021/ja01200a039https://doi.org/10.1021/ja01200a039research-articleACS PublicationsRequest reuse permissionsArticle Views998Altmetric-Citations136LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
ChemInform Abstract: ELECTROANALYTICAL INVESTIGATION ON DICHLOROBIS(TERTIARY PHOSPHINE)PLATINUM(II) COMPLEXES (1976)

Abstract Mittels cyclischer Voltammetrie und Potential‐kontrollierter Elektrolyse in Acetonitril unter Verwendung von Pt‐ und Hg‐Elektroden wird gezeigt, daß die untersuchten Pt(II)‐Komplexe (II) zu den Phosphin‐Pt(IV)‐Komplexen (I) oxidierbar und zu den Pt(0)‐Komplexen (III) reduzierbar sind, wobei die trans‐Komplexe leichter als die cis‐Analogen oxidiert werden.
Let’s play a game of chutes and ladders (2013)

In non-polarized cells, calcium-induced exocytosis of "conventional" lysosomes is important in diverse processes like membrane repair after exposure to pore-forming toxins and clearance of cellular debris. Resealing of torn membranes is especially critical for barrier epithelia that directly interact with pathogens and toxins, which can result in membrane microdisruptions and lesions. However, whether lysosomes participate in membrane repair in polarized epithelia has been an open question. We recently reported that in polarized Madin-Darby canine kidney (MDCK) cells, localized influx of calcium induces lysosomes to fuse with the basolateral membrane. This spatial segregation of exocytosis depends on an intact actin cytoskeleton, membrane cholesterol and restricted distribution of fusion machinery such as the t-SNARE syntaxin 4. Our data show that the polarity of syntaxin 4 (which is regulated by the clathrin adaptor protein AP-1) dictates whether lysosomes parachute down to the basolateral membrane or take a ladder up to the apical membrane. Here, we speculate about additional machinery (such as the lysosomal calcium sensor synaptotagmin VII and the v-SNARE VAMP7) that could be involved in polarized fusion of lysosomes with the epithelial membrane. We also discuss the potential importance of lysosome exocytosis in maintaining membrane integrity in the retinal pigment epithelium, the primary tissue affected in blinding diseases such as age-related macular degeneration.
Novel CW measurement of amplitude and phase transfer functions of opto electronic devices (2003)

We present a new and simple technique for measuring simultaneously the amplitude and phase transfer functions of semiconductor devices. These data allow us to calculate the linewidth enhancement factor, , and first results are shown.
Inhibition in ester hydrolyses catalyzed by carboxypeptidase A (1967)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTInhibition in ester hydrolyses catalyzed by carboxypeptidase AShoji. Awazu, Frederick W. Carson, Philip Layton. Hall, and Emil T. KaiserCite this: J. Am. Chem. Soc. 1967, 89, 14, 3627–3631Publication Date (Print):July 1, 1967Publication History Published online1 May 2002Published inissue 1 July 1967https://pubs.acs.org/doi/10.1021/ja00990a049https://doi.org/10.1021/ja00990a049research-articleACS PublicationsRequest reuse permissionsArticle Views39Altmetric-Citations11LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
The effect of copper and iron complexation on removal of cyanide by ozone (1988)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe effect of copper and iron complexation on removal of cyanide by ozoneMirat D. Gurol and Timothy E. HoldenCite this: Ind. Eng. Chem. Res. 1988, 27, 7, 1157–1162Publication Date (Print):July 1, 1988Publication History Published online1 May 2002Published inissue 1 July 1988https://doi.org/10.1021/ie00079a012RIGHTS & PERMISSIONSArticle Views269Altmetric-Citations18LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (724 KB) Get e-Alerts Get e-Alerts
Evolution of the in-gap state in high-<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mrow><mml:msub><mml:mrow><mml:mi mathvariant="italic">T</mml:mi></mml:mrow><mml:mrow><mml:mi mathvariant="italic">c</mml:mi></mml:mrow></mml:msub></mml:mrow></mml:math>cuprates (1992)

An exact diagonalization technique on small lattices is used to calculate the single-particle spectral function A(k,\ensuremath{\omega}) for one- and three-band Hubbard models at various parameter values and doping rates, thereby examining the low-energy electronic structure (or in-gap state) of the doped ${\mathrm{CuO}}_{2}$ plane in high-${\mathit{T}}_{\mathit{c}}$ superconducting cuprates. It is illustrated that, by carrier doping, the dispersive state of the charge excitation gap at half filling undergoes a strongly momentum-dependent spectral-weight transfer, and evolves into the new state with a free-electron-like dispersion that forms the in-gap state characteristic of a large Fermi surface consistent with Luttinger's sum rule. The quasiparticlelike band narrowing observed is shown to depend sensitively on the parameter values and doping rate.
Metabolic control of arthritis: Switch pathways to treat (2016)

A shunting of glucose metabolism to the pentose phosphate pathway in rheumatoid arthritis T cells causes exhaustion of oxidants, enhanced cell proliferation, and differentiation toward the T helper 1 (TH1) and TH17 programs (Yanget al, this issue).
Cascade Protection with Transient Voltage Surge Suppressors (TVSS) in Variable Speed Drive for Electro-Submergible Pumps (2006)

Every year in the BOSCAN oil fields, operated by Chevron, there are significant losses of oil production, due to damages found in electronic components mainly after severe electrical storms. The variable speed drives which are feeding the electro-submergible pumps are found to be most susceptible to failures of this nature. With the purpose of decreasing these failures, we considered the IEEE approach to facility protection and the potential application for variable speed drives, doing a series installation of transient voltage surge suppressors (TVSS) at different key points inside the drives. The cascade scheme for the protection of variable speed drives was devised, performed and validated in laboratory tests performed in the USA. This cascade protection scheme is currently being implemented and monitored in sixty wells of the BOSCAN field. This paper documents the criteria considered, the methodology implemented and the tests performed to validate cascade protection for variable speed drives
The occurrence of both amide and thiolate forms of the benzoxazole-2-thionate anion (C<sub>7</sub>H<sub>4</sub>ONS<sup>–</sup>) in the same molecule: synthesis and crystal structure of C<sub>7</sub>H<sub>4</sub>ONSNa[µ-OP(NMe<sub>2</sub>)<sub>3</sub>]<sub>3</sub>NaC<sub>7</sub>H<sub>4</sub>ONS (1995)

The reaction of benzoxazole-2(1H)-thione (C7H5ONS) with either solid NaOH or NaH, in toluene solution, in the presence of hexamethylphosphoramide (hmpa), afforded the new complex C7H4ONSNa(µ-hmpa)3NaC7H4ONS 1 in good yield. In contrast to similar lithium and calcium complexes, 1 resists the incorporation of water into the metal co-ordination sphere. Characterisation by single-crystal X-ray diffraction revealed that, in the solid state, complex 1 is dimeric through three bridging hmpa ligands. This dimer is unsymmetrically co-ordinated by C7H4ONS– anions, one metal centre being co-ordinated by a N,S-chelated anion formally derived from the thiol tautomer, the other being co-ordinated only through N of an anion formally derived from the amine tautomer of benzoxazole-2(1H)-thione. In addition to these unusual structural features, the dimeric complex 1 is further associated by weak C–H ⋯ O and C–H ⋯ S hydrogen bonding interactions.
Distributed Extended Kalman Filtering for Reliable Navigation on Lunar Surface (2011)

This paper presents a reliable surface navigation algorithm based on distributed extended Kalman filtering (DEKF) method. The proposed algorithm enables the network of sensors on the lunar surface to act as a collective observer for positioning the rovers or astronauts, making the navigation process more reliable by eliminating the need to a centralized estimator. The performance and effectiveness of the DEKF will be compared to those of an extended Kalman filter (EKF) implemented in a central manner by making use of the simulation data collected from the model of a network of rovers moving on the lunar surface.
Molecular Dynamics Simulations of Surfactant Functionalized Nanoparticles in the Vicinity of an Oil/Water Interface (2010)

The localization of nanoparticles (NPs) at fluid/fluid interfaces has emerged as an effective self-assembly method. To understand the fundamentals of this localization mechanism, it is necessary to quantify the physical behavior of NPs in the vicinity of a fluid interface. Conventional theories treat the NP as a rigid object whose equilibrium position is dictated by the balance of its surface tensions with the two fluids. However, most NPs are functionalized with “soft” organic surface layers which play a large role in determining the shape of the NP. Through molecular dynamics simulations, we show that the functionalizing layer also greatly alters the interfacial behavior of the NP beyond the scope of common theory. Furthermore, we characterize the effect of the surface density of functionalizing molecules on the NP deformability. Our results have implications on the experimental interpretation of NP contact angles and may be useful for future theory development.
The Cytoskeleton Maintains Organelle Partitioning Required for Single-Cell C4 Photosynthesis in Chenopodiaceae Species (2006)

Recently, three Chenopodiaceae species, Bienertia cycloptera, Bienertia sinuspersici, and Suaeda aralocaspica, were shown to possess novel C(4) photosynthesis mechanisms through the compartmentalization of organelles and photosynthetic enzymes into two distinct regions within a single chlorenchyma cell. Bienertia has peripheral and central compartments, whereas S. aralocaspica has distal and proximal compartments. This compartmentalization achieves the equivalent of spatial separation of Kranz anatomy, including dimorphic chloroplasts, but within a single cell. To characterize the mechanisms of organelle compartmentalization, the distribution of the major organelles relative to the cytoskeleton was examined. Examination of the distribution of the cytoskeleton using immunofluorescence studies and transient expression of green fluorescent protein-tagged cytoskeleton markers revealed a highly organized network of actin filaments and microtubules associating with the chloroplasts and showed that the two compartments in each cell had different cytoskeletal arrangements. Experiments using cytoskeleton-disrupting drugs showed in Bienertia and S. aralocaspica that microtubules are critical for the polarized positioning of chloroplasts and other organelles. Compartmentalization of the organelles in these species represents a unique system in higher plants and illustrates the degree of control the plant cell has over the organization and integration of multiorganellar processes within its cytoplasm.
Organized Self-Assembly of Janus Micromotors with Hydrophobic Hemispheres (2013)

Organized self-assemblies of Janus catalytic motors, induced by hydrophobic surface interactions involving multiple motor/motor and motor/nonmotor particles, display controlled coordinated self-propulsion. The influence of the self-assembled structures upon the motion behavior is investigated. A dynamic 'on-the-fly' assembly is observed during the continuous movement of the individual components, along with changes in the motion behavior. Organized assemblies of multiple motor/nonmotor particles are also illustrated toward optimal cargo transport and delivery. Such controlled structures and motion of chemically powered Janus micromotor assemblies hold considerable promise for the creation of intelligent nanomachines that perform collective tasks.
Probabilities for low-energy small-angle scattering in collisions of neutral particles (2006)

General and analytical expressions for probabilities for center-of-mass scattering into small angles $(0\ifmmode^\circ\else\textdegree\fi{}\ensuremath{\leqslant}\ensuremath{\vartheta}\ensuremath{\lesssim}3\ifmmode^\circ\else\textdegree\fi{})$ in elastic neutral-neutral collisions with low impact energy $(0.05\phantom{\rule{0.3em}{0ex}}\mathrm{eV}\ensuremath{\lesssim}E\ensuremath{\lesssim}0.5\phantom{\rule{0.3em}{0ex}}\mathrm{eV})$ are derived. Several theories of the differential scattering into the small angles are analyzed in order to establish the most reliable differential cross section for the collisions. The ``best'' cross section is then used to derive the corresponding (analytical) scattering probabilities. The approach is used to calculate the absolute values of the small-angle, low-energy differential cross sections and the scattering probabilities for the Li-Hg, Na-Hg, and K-Hg interactions.
Micro-Raman Scattering Properties of Highly Oriented AlN Films (1998)

Micro-Raman scattering by highly oriented crystalline aluminum nitride has been measured. Phonon modes in AlN were identified in different scattering geometry configurations and scattering polarizations. The phonon modes revealed that aluminum nitride films are highly oriented with the wurtzite c-axis direction normal to the film plane. The Raman scattering modes are broadened and shifted due to grain boundaries and other defects in the films. The defect scattering was analysed using the phonon confinement model. These results were compared with results obtained from X-ray diffraction powder patterns and high-resolution transmission electron microscopy.
Reshaping of telecom band optical signals using programmable pump pulses (2017)

Get PDF Email Share Share with Facebook Tweet This Post on reddit Share with LinkedIn Add to CiteULike Add to Mendeley Add to BibSonomy Get Citation Copy Citation Text P. Manurkar, N. Jain, P. Kumar, and G. S. Kanter, "Reshaping of telecom band optical signals using programmable pump pulses," in Conference on Lasers and Electro-Optics, OSA Technical Digest (online) (Optica Publishing Group, 2017), paper JTh2A.127. Export Citation BibTex Endnote (RIS) HTML Plain Text Citation alert Save article
Organoboron compounds. Part VIII. Aliphatic and aromatic diboronic acids (1970)

Diboronic acids (HO)2B·R·B(OH)2(where R = polymethylene, arylene, or thiophen-2,5-diyl) are prepared by reactions of methyl borate with difunctional Grignard reagents and are characterised by the formation of cyclic esters with various diols. The polymethylenediboronic acids are much more resistant to aerial oxidation than are the corresponding alkylboronic acids. All the diboronic acids undergo dehydration to the corresponding polymeric anhydrides, the aromatic compounds requiring temperatures >230°. Reactions which result in deboronation or in the formation of amine complexes are described. Thiophen-2,5-diyldiboronic acid undergoes hydrogenolysis on treatment with Raney nickel to give tetramethylenediboronic acid.
Wendell, Barrett, [1893] December 3 (1893)

34, De Vere Gardens; UVA dates as [n.y.], but Jobe's year of [1893] agrees with James' use of letterhead
Dispersions of Liquid Crystalline Phases of the Monoolein/Oleic Acid/Pluronic F127 System (2002)

Aqueous dispersions of lyotropic liquid crystalline phases (cubosomes and hexosomes) were prepared using lipid mixtures, monoolein (MO) and oleic acid (OA), and emulsifier Pluronic F127 by changing their composition. The size and internal structure of the prepared particles were characterized by dynamic light scattering and small-angle X-ray scattering, respectively. At the weight ratio of MO:OA = 5:5 and 8 wt % F127 to the total lipid mixtures, particles with a diameter of ca. 140 nm and including an inverted hexagonal (HII) phase were formed. With an increase in the F127 concentration, the particle size decreased, but the internal structure (lattice constant) did not change, suggesting that F127 absorbs at the particle surface with little incorporation in the HII phase. The lipid ratios and solvent pH strongly affected the morphology of the internal structure of the particles. By increasing the weight fraction of OA in the lipid mixtures, the internal structure transformed in the order of bicontinuous cubic-inverted hexagonal-inverted cubic. In addition, transformation from the cubosome to the hexosome was observed by decreasing the pH, suggesting that the interior of the nanoparticles is responsive to the outer environment.