gebhart/patrepeval huggingface dataset:
Distributed Dynamic Speed Scaling (2010)

In recent years we have witnessed a great interest in large distributed computing platforms, also known as clouds. While these systems offer enormous computing power, they are major energy consumers. In existing data centers CPUs are responsible for approximately half of the energy consumed by the servers. A promising technique for saving CPU energy consumption is dynamic speed scaling, in which the speed at which the processor is run is adjusted based on demand and performance constraints. In this paper we look at the problem of allocating the demand in the network of processors (each being capable to perform dynamic speed scaling) to minimize the global energy consumption/cost subject to a performance constraint. The nonlinear dependence between the energy consumption and the performance as well as the high variability in the energy prices result in a nontrivial resource allocation. The problem can be abstracted as a fully distributed convex optimization with a linear constraint. On the theoretical side, we propose two low-overhead fully decentralized algorithms for solving the problem of interest and provide closed-form conditions that ensure stability of the algorithms. Then we evaluate the efficacy of the optimal solution using simulations driven by the real-world energy prices. Our findings indicate a possible cost reduction of 10-40% compared to power-oblivious 1/N load balancing, for a wide range of load factors.
Studies of spatial sensitivity of the hydrological response to earthquakes (2007)

Numerous observed earthquake induced hydrological changes inferred some sensitive wells could detect the tiny signals of the crustal deformation. But the reasons and mechanisms included for the sensitive wells are not well-known. Some previously study (Matsumoto et al., 2003; Roeloffs et al., 2003) show individual mechanism could be the reasons made the wells with high sensitivity to earthquake. Also the earthquake induced hydrological changes shows the high variances in spatial distribution (Lai et al., 2005). To make a criteria for choosing sensitive sites or wells are still quite a big challenge. In this study, we using the observations of the groundwater and earthquake monitoring network in Taiwan act as the dense observation dataset to the earthquake induced hydrological responses. The comparison of the all events (detectable and non detectable) in groundwater level and the inferred volumetric strain step in response to the earthquake events were discuss. These observations had been geostatistically analysis for estimate the sensitivity of the observation well to different spatial regions. From the spatial analysis of the detect ability, they shows the highly anisotropy and heterogeneity in four wells. They could partly explain the different responses of earthquake induced groundwater changes. Tectonic and structural geology setting could be the main reason control the spatial difference of earthquake induced groundwater changes (Fault-Barrier Effect). The strain model usually could explain the type of the coseismic change, but the amplitudes usually not fit to the homogeneous assumption. The Structural anisotropy and mechanical heterogeneity should be considered to improve the volumetric strain estimation. The results issued the limitation and ability of the detection of the observation well spatially. Base on the spatial distribution of the detection, we should choose fitted sites or wells for the purpose.
Vehicle Systems Panel deliberations (1993)

The Vehicle Systems Panel addressed materials and structures technology issues related to launch and space vehicle systems not directly associated with the propulsion or entry systems. The Vehicle Systems Panel was comprised of two subpanels - Expendable Launch Vehicles & Cryotanks (ELVC) and Reusable Vehicles (RV). Tom Bales, LaRC, and Tom Modlin, JSC, chaired the expendable and reusable vehicles subpanels, respectively, and co-chaired the Vehicle Systems Panel. The following four papers are discussed in this section: (1) Net Section components for Weldalite Cryogenic Tanks, by Don Bolstad; (2) Build-up Structures for Cryogenic Tanks and Dry Bay Structural Applications, by Barry Lisagor; (3) Composite Materials Program, by Robert Van Siclen; (4) Shuttle Technology (and M&S Lessons Learned), by Stan Greenberg.
Metal-centered oxygen atom transfer reactions (1987)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTMetal-centered oxygen atom transfer reactionsR. H. HolmCite this: Chem. Rev. 1987, 87, 6, 1401–1449Publication Date (Print):December 1, 1987Publication History Published online1 May 2002Published inissue 1 December 1987https://pubs.acs.org/doi/10.1021/cr00082a005https://doi.org/10.1021/cr00082a005research-articleACS PublicationsRequest reuse permissionsArticle Views7003Altmetric-Citations900LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Association between SLE nephritis and polymorphic variants of the CRP and Fc RIIIa genes (2007)

Polymorphic variants of the CRP and Fcgamma-receptor genes are associated with the clinical phenotype in SLE. Our findings suggest an immune complex-mediated pathogenesis in nephritis and seizures, while development of arthritis may depend on other pathogenetic pathways.
Effect of Arginine-Rich Peptide Length on the Structure and Binding Strength of siRNA–Peptide Complexes (2013)

Heparin decomplexation experiments, as well as all-atom (AA) and coarse-grained (CG) molecular dynamics (MD) simulations, were performed to determine the effect of the size of arginine(Arg)-rich peptides on the structure and binding strength of the siRNA-peptide complex. At a fixed peptide/siRNA mole ratio of 5:1 or 10:1, the siRNA complexes with peptides longer than nine Arg residues are more easily decomplexed by heparin than are those with nine Arg residues. At these mole ratios, peptides longer than nine Arg residues have cationic/anionic charge ratios in excess of unity, and produce more weakly bound complexes than nine Arg residue ones do. AA simulations of mixtures of peptides with a single siRNA show formation of an electrostatically induced complex, and the longer peptides produce a larger complex, but with no significant increase in the number of Arg residues bound to the siRNA. Larger-scale CG-MD simulations show that multiple siRNAs can be linked together by peptides into a large complex, as observed in the experiments. The peptides longer than nine residues, which at mole ratio 5:1 yield a peptide/siRNA charge ratio in excess of unity, include many noninteracting Arg residues, which repel each other electrostatically. This leads to a less dense complex than for 9-residue peptides, which can explain why these longer complexes are more easily decomplexed by heparin molecules, as observed in the experiments. The key role of the charge ratio is supported by simulations that show that, at a mole ratio of 2.5 peptides per siRNA, the longer 18-residue peptide has a charge ratio of roughly unity and also shows a tight complex, just as the 9-residue peptide does at a 5:1 mole ratio, where its charge ratio is also unity.
An Improved Water Distribution System Chlorine Decay Model Using EPANET MSX (2012)

One of the most common uses of water distribution system water quality modeling is to simulate the chlorine residual in the network. Most standard software pac…
Consideration of Moving Tooth Load in Gear Crack Propagation Predictions (2000)

Robust gear designs consider not only crack initiation, but crack propagation trajectories for a fail-safe design. In actual gear operation, the magnitude as well as the position of the force changes as the gear rotates through the mesh. A study to determine the effect of moving gear tooth load on crack propagation predictions was performed. Two-dimensional analysis of an involute spur gear and three-dimensional analysis of a spiral-bevel pinion gear using the finite element method and boundary element method were studied and compared to experiments. A modified theory for predicting gear crack propagation paths based on the criteria of Erdogan and Sih [18] was investigated. Crack simulation based on calculated stress intensity factors and mixed mode crack angle prediction techniques using a simple static analysis in which the tooth load was located at the highest point of single tooth contact was validated. For three-dimensional analysis, however, the analysis was valid only as long as the crack did not approach the contact region on the tooth.
A new test set for validating predictions of protein–ligand interaction (2002)

We present a large test set of protein-ligand complexes for the purpose of validating algorithms that rely on the prediction of protein-ligand interactions. The set consists of 305 complexes with protonation states assigned by manual inspection. The following checks have been carried out to identify unsuitable entries in this set: (1) assessing the involvement of crystallographically related protein units in ligand binding; (2) identification of bad clashes between protein side chains and ligand; and (3) assessment of structural errors, and/or inconsistency of ligand placement with crystal structure electron density. In addition, the set has been pruned to assure diversity in terms of protein-ligand structures, and subsets are supplied for different protein-structure resolution ranges. A classification of the set by protein type is available. As an illustration, validation results are shown for GOLD and SuperStar. GOLD is a program that performs flexible protein-ligand docking, and SuperStar is used for the prediction of favorable interaction sites in proteins. The new CCDC/Astex test set is freely available to the scientific community (http://www.ccdc.cam.ac.uk).
<i>In Vitro</i> and <i>In Vivo</i> Characterizations of Pichinde Viral Nucleoprotein Exoribonuclease Functions (2015)

Arenaviruses, such as Lassa, Lujo, and Machupo viruses, can cause severe and deadly hemorrhagic fever diseases in humans, and there are limited preventative and treatment options against these diseases. Development of broad-spectrum antiviral drugs depends on a better mechanistic understanding of the conserved arenavirus proteins in viral infection. The nucleoprotein (NPs) of all arenaviruses carry a unique exoribonuclease (RNase) domain that has been shown to be critical for the suppression of type I interferons. However, the functional roles of the NP RNase in arenavirus replication and host immune suppression have not been characterized systematically. Using a prototype arenavirus, Pichinde virus (PICV), we characterized the viral growth and innate immune suppression of recombinant RNase-defective mutants in both cell culture and guinea pig models. Our study suggests that the NP RNase plays an essential role in the suppression of host innate immunity, and possibly in viral RNA replication, and that it can serve as a novel target for developing antiviral drugs against arenavirus pathogens.
HIGH ENERGY PROPELLANT INGREDIENT RESEARCH (1966)

Abstract : The thermal stability of aluminum hydride (Olane 58) has been significantly improved by aging and water treatment. The effect is believed to be due to a surface coating of bayerite, Al(OH)3. These treated samples demonstrated thermal stabilities of less than 1% decomposition in the Taliani Test at 100 C for 8-12 hours or at 60 C for 50-75 days. Studies of the synthesis of Olane 58 by the solid LiAlH4 preparatory technique or through the addition of free radical inhibitors did not indicate the superiority of these modifications in present processes. Direct crystallization of unsolvated aluminum hydride was demonstrated from a mixed toluene-ether solution. Although the data from the Differential Scanning Calorimetry (DSC) scans both programmed and isothermal provide some insight into the thermal character of aluminum hydride, no meaningful correlations to Taliani Tests at 60 C and 100 C could be made for decomposition as low as 1%. Conductivity studies of the LiAlH4-AlCl3 reaction under a variety of conditions indicate the formation of a AlH3 2LiAlH4 complex and chlorolane species.
ChemInform Abstract: X‐Ray Diffraction, <sup>119</sup>Sn Moessbauer and Thermal Study of SnSe—Bi<sub>2</sub>Se<sub>3</sub> System. (2008)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Characterization of Thermal Sprayed Aluminum and Stainless Steel Coatings for Clean Laser Enclosures (2000)

Surfaces of steel structures that enclose high-fluence, large-beam lasers have conventional and unconventional requirements. Aside from rust prevention, the surfaces must resist laser-induced degradation and the contamination of the optical components. The latter requires a surface that can be precision cleaned to low levels of particulate and organic residue. In addition, the surface treatment for the walls should be economical to apply because of the large surface areas involved, and accommodating with intricate joint geometries. Thermal sprayed coatings of aluminum (Al) and stainless steel are candidate surface materials. Coatings are produced and characterized for porosity, smoothness, and hardness. These properties have a bearing on the cleanliness of the coating. The laser resistance of Al and 3 16L coatings are given. The paper summarizes the characterization of twin-wire-arc deposited Al, high-velocity-oxygen-fueled (HVOF) deposited Al, flame-sprayed 316L, and HVOF deposited316L. The most promising candidate coating is that of HVOF Al. This Al coating has the lowest porosity (8%) compared the other three coatings and relatively low hardness (100 VHN). The as-deposited roughness (Ra) is 433 pinches, but after a quick sanding by hand, the roughness decreased to 166 pinches. Other post-coat treatments are discussed. HVOF aluminum coatings are demonstrated. Al coatings are corrosion barriers for steel, and this work shows promising resistance to laser damage and low particulation rates.
Gastrointestinal Hormone Responses to Meals Before and After Gastric Bypass and Vertical Banded Gastroplasty (1990)

The purpose of the study was to examine the gastrointestinal hormone responses to meals in morbidly obese patients before and after Roux-en-Y gastric bypass (GBP; n = 9) or vertical banded gastroplasty (VBG; n = 7). On consecutive days before and after operation, we measured changes in peripheral blood levels of glucose, insulin, enteroglucagon, serotonin, vasoactive intestinal polypeptide (VIP), and cholecystokinin (CCK) in response to a standardized glucose or protein-fat meal. The percentage of excess weight lost at 6 months after operation was 66.3% +/- 4% and 41.8% +/- 5% for GBP and VBG, respectively (p less than 0.01). The 3-hour integrated glucose response to a glucose meal decreased from 145.3 +/- 33.7 to 75.8 +/- 15.7 g min/L (p less than 0.02) after GBP. This was associated with a decrease in 3-hour integrated insulin response from 22.8 +/- 8.2 to 10.5 +/- 4.9 mU min/L. Vertical banded gastroplasty patients had lesser reductions of hyperglycemia and hyperinsulinemia. Neither the CCK, serotonin, nor VIP responses to meals were altered by either operation. The 3-hour integrated enteroglucagon response to glucose increased markedly in GBP patients after operation from 11.8 +/- 6 to 133.4 +/- 38 nmol min/mL (p less than 0.02). This increase in enteroglucagon occurred at the same time as development of dumping symptoms, which occurred exclusively in GBP patients after glucose but not protein. We conclude that (1) GBP surgery for morbid obesity results in amelioration of glucose intolerance and hyperinsulinemia, (2) CCK does not mediate an endocrine satiety effect of surgery, (3) GBP is associated with an exaggerated enteroglucagon response to glucose, and (4) enteroglucagon appears to be a marker of the dumping syndrome in GBP patients.
A hybrid moving least squares and natural element method for direct enforcement of boundary conditions and fast three dimensional computations (2005)

International audience
„Korrekt gefaltete“ Proteine - ein metastabiler Zustand? (2002)

Morbus Alzheimer, Diabetes vom Typ II, Creutzfeldt-Jakob-Krankheit und Erkrankungen unter Amyloid-Bildung: In all diesen pathologischen Situationen durchlaufen gut gefaltete Proteine einen irreversiblen Übergang vom korrekt gefalteten Zustand in eine kollabierte, β-Faltblatt-reiche Struktur. In diesem Beitrag wird postuliert, dass der aggregierte Zustand das globale Minimum der Gibbs-Energie für jedes beliebige Protein-Ensemble darstellt und dass bei unbegrenzter Zeit jede Proteinlösung oberhalb einer kritischen Konzentration irgendwann die Strukturumwandlung in den aggregierten Zustand durchlaufen wird.
CORRESPONDENCE Limitations of Magnesium Levels Study (1989)

To the Editor: Investigators seeking to identify associations between an outcome of interest and one or more clinical variables frequently compare a study group of interest (cases) to a suitable group of matched controls. If other factors known to affect outcome are not distributed equally between these two groups, their independent effects must be controlled through stratified analysis or multivariate statistical techniques. Adequate numbers of cases and controls must be compared in order to generate a study with sufficient power to identify clinically important effects. In any subsequent report limitations in study design should be clearly identified and systematically addressed. Finally, the author's conclusions should be clearly supported by their study results. In one way or another, all of these principles were violated by the authors of Levels in Cardiac Arrest Victims: Relationship Between Magnesium Levels and Successful Resuscitation [November 1987;16:1195-1199]. whatsoever on survival, are therefore issues left open to question. Given limited case numbers, an inappropriate control group, absent data regarding important confounding variables, and little biochemical evidence of cause or effect, the authors' recommendation that we should order stat magnesium levels and correct abnormalities seems premature at best. Abnormalities of serum magnesium concentration may well play a small but important role in a subset of patients in cardiac arrest, but the strength and nature of this association remains to be defined.
Chromoelectric dipole moments of heavy quarks and purely gluonic<i>CP</i>violating operators (1992)

We study effects of induced CP-nonconserving effective operators involving the gluon field strength as a result of integrating out the heavy-quark field which carries a chromoelectric dipole moment. The induced gluonic operators of dimension 8 may be the dominant mechanism for generating the neutron electric dipole moment.
Frequency of anti-AG-4 antibody in patients with uterine cervical cancer and controls. (1978)

Association of herpesvirus type-2 (HSV-2) with cervical cancer was studied from seroepidemiological viewpoint, using early antigen induced in Hep-2 cells by HSV-2 4 hr after infection (AG-4). The AG-4 antibody was assayed by the microquantitative complement fixation method. Antibody to AG-4 was respectively detected in 47% and 14% of cervical cancer patients and controls (P less than 0.001). There was a tendency of the antibody prevalence to increase with clinical stage. There was no correlation between prevalence of AG-4 antibody and that of HSV-2 neutralizing antibody estimated by the kinetics of neutralization assay, confirming previous conclusions that AG-4 differs from viral antigens involved in neutralization. Although previous study could not confirm higher prevalence of neutralizing antibody to HSV-2 in cancer patients, the present data suggest that HSV-2 is not unrelated to cervical cancer.
THE PREPARATION OF trans 1,4-POLYBUTADIENE BY RHODIUM SALTS IN SOLUTION (1961)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTTHE PREPARATION OF trans 1,4-POLYBUTADIENE BY RHODIUM SALTS IN SOLUTIONRobert E. Rinehart, Homer P. Smith, Harry S. Witt, and Hendrik Romeyn Jr.Cite this: J. Am. Chem. Soc. 1961, 83, 23, 4864–4865Publication Date (Print):December 1, 1961Publication History Published online1 May 2002Published inissue 1 December 1961https://pubs.acs.org/doi/10.1021/ja01484a043https://doi.org/10.1021/ja01484a043research-articleACS PublicationsRequest reuse permissionsArticle Views200Altmetric-Citations85LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Corrections to enhanced optical nonlinearity of superlattices (1984)

In recent publications, a large enhancement of the third order nonlinear optical susceptibility was predicted for GaAs–GaAlAs superlattices, as a result of the band nonparabolicities introduced by the additional periodicity of the superlattice. These predictions, based on the tight binding model, are here extended to the more realistic Kronig–Penney model. Results show that corrections to tight binding are non-negligible; however, enhancements of χ(3) are still large, but reduced by approximately 30%–50% over previous estimates.