gebhart/patrepeval huggingface dataset:
Nanocomposites de matriz epoxi: caracterización de la interfase por fluorescencia (2016)

La utilización de la espectroscopia de fluorescencia ha demostrado ser una herramienta potente y eficaz para evaluar las propiedades de la interfase en nanocomposites de matriz epoxi. Utilizando nanopartículas de sílice como nanorefuerzo se han preparado diferentes nanocomposites variando el contenido de nanorrefuerzos, cambiando así el aspecto estructural de la interfase con diferentes estados de dispersión. Se han modificado superficialmente las nanopartículas para generar diferentes interacciones carga/matriz para así evaluar su impacto en las propiedades macroscópicas. Los tratamientos superficiales de las nanopartículas de sílice han permitido también localizar un cromóforo en diferentes regiones de la interfase, y estudiar sus propiedades a partir la emisión de fluorescencia. Se ha estudiado la formación de la red termoestable a nivel macroscópico, y a nivel local utilizando la espectroscopia de fluorescencia. Se ha mostrado que la adición de nanopartículas de sílice acelera la reacción de curado a nivel macroscópico. A nivel interfacial, con la información proporcionada por la espectroscopia de fluorescencia, se ha podido apreciar que la reacción de curado ocurre antes en la zona interfacial y de forma más acelerada que en el seno de la matriz y que estos fenómenos dependen de la naturaleza de la interfase. Se ha realizado un estudio de la dinámica de la relajación estructural de la matriz polimérica y de la temperatura de transición vítrea asociada. Se ha demostrado que macroscópicamente existe en estos nanocomposites dos efectos antagonistas sobre la dinámica de las cadenas poliméricas: una restricción de movilidad a nivel de la interfase y un fenómeno de ruptura de la red termoestable que contribuye a aumentar la movilidad segmental. Ambos efectos dependen de la naturaleza de la interfase. La localización del cromóforo en diferentes regiones de la interfase ha permitido determinar su extensión y diferenciar su comportamiento estructural del de la matriz.
Ferrocene Derivatives. Part I. The Direct Synthesis of Substituted Ferrocenes (1954)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTFerrocene Derivatives. Part I. The Direct Synthesis of Substituted FerrocenesP. L. PausonCite this: J. Am. Chem. Soc. 1954, 76, 8, 2187–2191Publication Date (Print):April 1, 1954Publication History Published online1 May 2002Published inissue 1 April 1954https://pubs.acs.org/doi/10.1021/ja01637a046https://doi.org/10.1021/ja01637a046research-articleACS PublicationsRequest reuse permissionsArticle Views2643Altmetric-Citations62LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Comparative evaluation of rejuvenation of spent residue hydroprocessing catalysts in the decoked (oxidic) and coked (sulfided) forms (1993)

Spent catalysts from residue hydroprocessing units constitue a major portion of solid wastes of the petroleum refining industry. They contain toxic metals that can be leached by water and pollute the environment. Their disposal as landfill is, therefore, environmentally restricted. Increasing emphasis has been placed in recent years on the development of alternative solutions to the spent catalyst problem. The most attractive solution is, of course, to rejuvenate and reuse the catalyst
Clinical and Neurobiological Perspectives of Empowering Pediatric Cancer Patients Using Videogames (2015)

Pediatric oncology patients often experience fatigue and physical and mental deconditioning during and following chemotherapy treatments, contributing to diminished quality of life. Patient empowerment is a core principle of patient-centered care and reflects one's ability to positively affect his or her own health behavior and health status. Empowerment interventions may enhance patients' internal locus of control, resilience, coping skills, and self-management of symptoms related to disease and therapy. Clinical and technological advancements in therapeutic videogames and mobile medical applications (mobile health) can facilitate delivery of the empowerment interventions for medical purposes. This review summarizes clinical strategies for empowering pediatric cancer patients, as well as their relationship with developing a "fighting spirit" in physical and mental health. To better understand physiological aspects of empowerment and to elucidate videogame-based intervention strategies, brain neuronal circuits and neurotransmitters during stress, fear, and resilience are also discussed. Neuroimaging studies point to the role of the reward system pathways in resilience and empowerment in patients. Taken together, videogames and mobile health applications open translational research opportunities to develop and deliver empowerment interventions to pediatric cancer patients and also to those with other chronic diseases.
Heme Distortions in Sperm-Whale Carbonmonoxy Myoglobin:  Correlations between Rotational Strengths and Heme Distortions in MD-Generated Structures (2002)

We have investigated the effects of heme rotational isomerism in sperm-whale carbonmonoxymyoglobin using computational techniques. Several molecular dynamics simulations have been performed for the two rotational isomers A and B, which are related by a 180 degrees rotation around the alpha-gamma axis of the heme, of sperm-whale carbonmonoxy myoglobin in water. Both neutron diffraction and NMR structures were used as starting structures. In the absence of an experimental structure, the structure of isomer B was generated by rotating the heme in the structure of isomer A. Distortions of the heme from planarity were characterized by normal coordinate structural decomposition and by the angle of twist of the pyrrole rings from the heme plane. The heme distortions of the neutron diffraction structure were conserved in the MD trajectories, but in the NMR-based trajectories, where the heme distortions are less well defined, they differ from the original heme deformations. The protein matrix induced similar distortions on the hemes in orientations A and B. Our results suggest that the binding site prefers a particular macrocycle conformation, and a 180 degrees rotation of the heme does not significantly alter the protein's preference for this conformation. The intrinsic rotational strengths of the two Soret transitions, separated according to their polarization in the heme plane, show strong correlations with the ruffling deformation and the average twist angle of the pyrrole rings. The total rotational strength, which includes contributions from the chromophores in the protein, shows a weaker correlation with heme distortions.
Providing Ultra-Reliable Low Latency Services for 5G with Unattended Datacenters (2018)

The strict requirements imposed by ultra-reliable low latency (uRLL) services in 5G can be costly for 5G network operators: low latency requires the deployment of distributed datacenters, while ultra-high reliability usually means attended datacenters. This paper checks whether it is possible to operate the datacenters hosting uRLL services without on-site support without affecting service availability. Overall, the paper shows that deploying additional redundant hardware and implementing uRLL services by exploiting these extra resources, the required availability levels can be maintained without on-site support, which may mean significant OPEX savings for 5G network operators planning country-wide coverage for uRLL services.
Optimizing the acoustic performance of turbochargers (2013)

Turbocharger usage is predicted to increase in passenger vehicles for reasons such as enabling engine downsizing and improving thermodynamic efficiency. In order to achieve customer expectations, the acoustic performance of the turbo needs to be engineered for a wide range of operating load conditions. This requires the turbo supplier to set component targets in CAE and identify undesirable noises early in the development process using test cell acoustic measurements. Noise from a turbocharger can be separated into two main categories: (1) aeroacoustic sources including blade pass, pulsation, surge and broadband flow noise (2) structureborne from vibration sources such as subsynchronous, first order imbalance, and component resonances. One technique for comparing compressor acoustic performance is noise mapping, where the in duct noise data are collected across the full turbo operating range and post processed into 3D plots. Audible noises that can be generated in a centrifugal turbocharger and methods of identifying sources during development are presented in detail.
Tandem Photocycloaddition−Retro-Mannich Fragmentation of Enaminones. A Route to Spiropyrrolines and the Tetracyclic Core of Koumine (2006)

Intramolecular [2 + 2] photocycloaddition of β-aminoalkylidene malonates gives transiently a cyclobutane which undergoes retro-Mannich fragmentation to a Δ1-pyrroline. The tandem sequence, exemplified in two series based on tryptamine and aminoethyl-1,4-cyclohexadiene, leads to a spiroindolopyrroline skeleton and to the nonindolenine portion of koumine.
RNA Interference Knockdown of BRASSINOSTEROID INSENSITIVE1 in Maize Reveals Novel Functions for Brassinosteroid Signaling in Controlling Plant Architecture (2015)

Brassinosteroids (BRs) are plant hormones involved in various growth and developmental processes. The BR signaling system is well established in Arabidopsis (Arabidopsis thaliana) and rice (Oryza sativa) but poorly understood in maize (Zea mays). BRASSINOSTEROID INSENSITIVE1 (BRI1) is a BR receptor, and database searches and additional genomic sequencing identified five maize homologs including duplicate copies of BRI1 itself. RNA interference (RNAi) using the extracellular coding region of a maize zmbri1 complementary DNA knocked down the expression of all five homologs. Decreased response to exogenously applied brassinolide and altered BR marker gene expression demonstrate that zmbri1-RNAi transgenic lines have compromised BR signaling. zmbri1-RNAi plants showed dwarf stature due to shortened internodes, with upper internodes most strongly affected. Leaves of zmbri1-RNAi plants are dark green, upright, and twisted, with decreased auricle formation. Kinematic analysis showed that decreased cell division and cell elongation both contributed to the shortened leaves. A BRASSINOSTEROID INSENSITIVE1-ETHYL METHANESULFONATE-SUPPRESSOR1-yellow fluorescent protein (BES1-YFP) transgenic line was developed that showed BR-inducible BES1-YFP accumulation in the nucleus, which was decreased in zmbri1-RNAi. Expression of the BES1-YFP reporter was strong in the auricle region of developing leaves, suggesting that localized BR signaling is involved in promoting auricle development, consistent with the zmbri1-RNAi phenotype. The blade-sheath boundary disruption, shorter ligule, and disrupted auricle morphology of RNAi lines resemble KNOTTED1-LIKE HOMEOBOX (KNOX) mutants, consistent with a mechanistic connection between KNOX genes and BR signaling.
Synthesis of coesite nanocrystals from ethane bridged periodic mesoporous organosilica at low temperature and extreme pressure (2010)

Coesite nanocrystals have been synthesized from periodic mesoporous organosilica (PMO) with (CH(2))(2) bridges heated at 300 °C for 150 min and 12 GPa. The crystals are not sintered, single crystalline, and have diameters of ca. 100-300 nm. Below 300 °C, an amorphous non-porous organosilica glass was obtained. Heating above 300 °C at 12 GPa results in the rapid crystal growth and micron size coesite crystals were formed.
Queues Subject to Service Interruption (1962)

A treatment is given of the M/G/1 queue with interruptions of Poisson incidence occasioned either by server breakdown or the arrival of customers with higher priority. Interruption times and priority service times have arbitrary distribution. After pre-emptive interruption, ordinary service is either repeated or resumed. The time dependent behavior of the system is discussed in a complete state space and the joint density in all system variables of this space is constructed systematically from the densities associated with a set of simpler first-passage problems. Equilibrium distributions are available as limiting forms and server busy period distributions obtained.
Value of ultrasound biomicroscopy for ciliodestructive procedures (1996)

Ciliodestructive procedures are commonly performed by the transscleral approach because ciliary processes are seldom visible. Thus the ablative energy is directed toward an "invisible" target whose position can only be estimated on the basis of experimental data. Ultrasound biomicroscopy has been recently introduced in ophthalmologic practice. This high-frequency ultrasound B-scan method gives real-time images of the subsurface structures of the anterior portion of the living eye at microscopic resolution. Ultrasound biomicroscopy perfectly visualizes the ciliary body and its surrounding structures and is a promising complementary tool for ciliodestructive procedures. The system has been used to image early and late ciliary body alterations after transscleral cyclophotocoagulation, to establish the position of the ciliary body to ensure correct laser probe placement, to locate ciliary body residuals for retreatment, and to rule out scleral damage after the procedure. An apparatus has been designed for simultaneous contact cyclophotocoagulation and ultrasound biomicroscopy analysis. A prospective randomized clinical trial is now needed to clarify the influence of ultrasound biomicroscopy on the success rate of ciliodestructive procedures.
The Role of Backbone Hydrogen Bonds in the Transition State for Protein Folding of a PDZ Domain (2014)

Backbone hydrogen bonds are important for the structure and stability of proteins. However, since conventional site-directed mutagenesis cannot be applied to perturb the backbone, the contribution of these hydrogen bonds in protein folding and stability has been assessed only for a very limited set of small proteins. We have here investigated effects of five amide-to-ester mutations in the backbone of a PDZ domain, a 90-residue globular protein domain, to probe the influence of hydrogen bonds in a β-sheet for folding and stability. The amide-to-ester mutation removes NH-mediated hydrogen bonds and destabilizes hydrogen bonds formed by the carbonyl oxygen. The overall stability of the PDZ domain generally decreased for all amide-to-ester mutants due to an increase in the unfolding rate constant. For this particular region of the PDZ domain, it is therefore clear that native hydrogen bonds are formed after crossing of the rate-limiting barrier for folding. Moreover, three of the five amide-to-ester mutants displayed an increase in the folding rate constant suggesting that the hydrogen bonds are involved in non-native interactions in the transition state for folding.
PCGAP: Users Guide and Algorithm Description (2000)

PCGAP is a software package, which was written to provide gamma-ray pulse height spectrum analysis on a personal computer platform using the Windows NT operating system. It is a collection of programs, which provide a wide range of operability extending from the single user environment to the general purpose counting room. Included in the package are necessary data structures and libraries used to compute quantitative radionuclide concentrations. PCGAP also contains techniques to decontaminate photopeak interferences; determine activity concentrations for radionuclides independent of their associated spectral photopeak size; and three methods to determine the energy scale of a spectrum. PCGAP performs a non-linear least squares fitting of a Gaussian function to spectral photopeaks. The fitting algorithm can fit up to five concurrent photopeaks using a common spectral background. The package includes a program that will automatically locate spectral photopeaks, fit them to a Gaussian function, identify the radionuclides associated with the found photopeaks, and compute a net activity concentration, and for an 8K spectrum do it in less than 30 seconds on a reasonably configured PC. PCGAP also includes a program which allows the operator to manually (using mouse clicks) identify photopeak locations, fit limits and background positions, initiate a fit to the photopeaks and then display the resulting Gaussian function forms. This interactive display function is particularly useful to resolve or properly fit photopeaks with complex adjacent structure and for photopeaks that are near the limit of detection.
Distribution of P<sub>1</sub>Type Nuclease in the Genus<i>Penicillium</i> (1977)

P1 type nuclease, which hydrolyzes RNA and heat-denatured DNA completely into 5’-mononucleotides and also shows 3’-nucleotidase activity, was widely distributed among various species belonging to the genus Penicillium such as P. expansum, P. notatum, P. steckii and P. meleagrinum. P1 type nucleases isolated from these strains were produced in a form of complex with malonogalactan when molds were grown on wheat bran. These enzymes showed similar characters in heat-stability (stable at 60°C), temperature optimum (60 to 70°C for RNA and heat denatured DNA, and 70°C for 3’-AMP) and sensitivity to EDTA. The enzymes from P. steckii and P. expansum were immunologically co-related to nuclease P1. In addition, many strains of Penicillium produced base-nonspecific RNases forming 3’-mononucleotides via 2’: 3 ’-cyclic nucleotides. These RNases showed similarity in heat-lability (completely inactivated at 60°C), temperature optimum (45 to 50°C), sensitivity to Zn2+ and Cu2+, and relative hydrolysis rate toward 2’: 3’-cyclic nucleotides (A≫C>U≫G).
Gait recognition using dynamic affine invariants (2004)

We present a method for recognizing classes of human gaits from video sequences. We propose a novel image based representation for human gaits. At any instance of time a gait is represented by a vector of affine invariant moments. The invariants are computed on the binary silhouettes corresponding to the moving body. We represent the time trajectories of the affine moment invariant vector as the output of a linear dynamical system driven by white noise. The problem of gait classification is then reduced to formulating distances and performing recognition in the space of linear dynamical systems. Results demonstrating the discriminate power of the proposed methods are discussed at the end.
Synthesis and structure of the<i>N</i>‐alkyl‐2,6‐dimethyl‐4‐oxopyridine‐3‐carboxylic acids (1993)

Abstract A range of N ‐alkyl‐2,6‐dimethyl‐4‐oxopyridine‐3‐carboxylic acids XV have been prepared via reactions of primary alkyl amines with differing 2,6‐dimethyl‐4‐oxopyran‐3‐carboxylate esters IX . The quantity of desired product formed and the character of by‐products formed are determined by the natures of the amine and ester IX respectively. X‐ray crystallography data for the N ‐ethyl analogue of XV indicates very strong intramolecular hydrogen bonding to be present, with the heterocyclic ring exhibiting considerable aromaticity.
Insulin-stimulated Insulin Secretion in Single Pancreatic Beta Cells (1999)

Functional insulin receptors are known to occur in pancreatic beta cells; however, except for a positive feedback on insulin synthesis, their physiological effects are unknown. Amperometric measurements at single, primary pancreatic beta cells reveal that application of exogenous insulin in the presence or absence of nonstimulatory concentrations of glucose evokes exocytosis mediated by the beta cell insulin receptor. Insulin also elicits increases in intracellular Ca2+ concentration in beta cells but has minimal effects on membrane potential. Conditions where the insulin receptor is blocked or cell surface concentration of free insulin is reduced during exocytosis diminishes secretion induced by other secretagogues, providing evidence for direct autocrine action of insulin upon secretion from the same cell. These results indicate that the beta cell insulin receptor can mediate positive feedback for insulin secretion. The presence of a positive feedback mechanism for insulin secretion mediated by the insulin receptor provides a potential link between impaired insulin secretion and insulin resistance.
A multi-functionally optoelectric platform for micro/nano particle manipulation and applications (2017)

This paper presents a simple optoelectrokinetic method for manipulating particles by simultaneously inducing electrohydrodnamic flow and electrokinetic motion. With carefully tuning the balance between several forces acting on particles, multiple manipulation capabilities including aggregation, translation, sorting, and patterning were achieved. In combination with bead-based immunoassays, we successfully performed fluorescent signal enhancement for a dilute analyte (~10 pg/mL), tumor necrosis factor-alpha (TNF-α), and achieved a proof of concept for simultaneous detection of dual biomarkers. The development of such a technique can provide insight to diagnosing diseases in the early stage.
Extraction of copper(II) from sulfuric acid by macrocycle-synergized cation exchange: Comparing a novel impregnated resin with its solvent-extraction analog (1993)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTExtraction of copper(II) from sulfuric acid by macrocycle-synergized cation exchange: Comparing a novel impregnated resin with its solvent-extraction analogBruce A. Moyer, G. N. Case, Spiro D. Alexandratos, and A. Amanda. KrigerCite this: Anal. Chem. 1993, 65, 23, 3389–3395Publication Date (Print):December 1, 1993Publication History Published online1 May 2002Published inissue 1 December 1993https://pubs.acs.org/doi/10.1021/ac00071a010https://doi.org/10.1021/ac00071a010research-articleACS PublicationsRequest reuse permissionsArticle Views159Altmetric-Citations22LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts