gebhart/patrepeval huggingface dataset:
Acoustic reflectivity of the human middle ear at high frequencies (1984)

A key parameter for network modeling of the human middle ear is the acoustic energy reflection coefficient, or reflectance, at the eardrum. At high frequencies (above 5 kHz) the reflectance is the only unambiguous indicator of acoustic behavior. Using a technique described recently [J. Acoust. Soc. Am. Suppl. 1 75, S11 (1984)] eardrum reflectance can be determined by measuring the spatial variation of acoustic phase along the ear canal. The main advantage of this technique is the small amount of space required for the measurements, so only shallow penetration of the ear canal by a probe is required. One problem, at times, with the preliminary work was involuntary movement of a subject's head. This has been largely overcome with the use of an improved head brace and microphone manipulator. This new system will be described and experimental results presented for several subjects. As with the earlier study, high eardrum reflectances, between 65% and 85%, are found above 10 kHz.
Le DPO et le secteur de la communication (2018)

Le correspondant informatique et libertés (CIL), dont la désignation est aujourd’hui facultative – hormis dans le cas où l’organisme souhaite obtenir le label « gouvernance » de la CNIL, est un acteur important de la conformité en matière de protection des données à caractère personnel, notamment au sein des grands organismes. L’actuel CIL a la possibilité de « faire toute recommandation au responsable des traitements » et de sensibiliser l’encadrement et l’ensemble des salariés sur la protection des données au sein de leur organisme. Avec l’entrée en vigueur du RGPD, le Data protection officer (DPO) va succéder, dans certains cas, à l’actuel CIL. Mais ses missions et son rôle sont, en raison de l’évolution de la conformité au sein des organismes, différents et plus étendus que ceux de l’actuel CIL. Pour autant, cette contribution revient sur le rôle spécifique du DPO dans le cadre des entreprises de communication afin de montrer à quel point son action sera déterminante lorsqu’il s’agira de mettre en œuvre des actions de marketing, d’encadrer et de communiquer sur le traitement et la protection des données. Dans certains cas, le CIL pourrait se maintenir et compléter son action afin de concilier au mieux le respect de la liberté d’expression au regard de la protection des données personnelles.
MOVEMENT ANALYSIS OF SCOLIOTIC SUBJECTS: A SCREENING AND EVALUATION TOOL? (2004)

Introduction and Objective: Although the causation and progression of adolescent idiopathic scoliosis (AIS) remains unclear, a recent review has highlighted a series of possible aetiological factors. Additionally, research investigations have indicated that the kinematic differences in various body segments may be a major contributing factor. The value of gait analysis systems employed to measure dynamic back movements in furthering understanding of spinal deformity has also been demonstrated by various studies. Research employing gait measurements have indicated asymmetries in the ground reaction forces and have suggested relationship between these asymmetries, neurological dysfunction and spinal deformity. This investigation, which formed part of a wider comprehensive study, was aimed at identifying asymmetries in lower limb kinematics and pelvic and back movements during level walking in scoliotic subjects that could be related to the spinal deformity. Design and Methodology: The research employed a movement analysis system and a strain gauge force platform to estimate time domain kinetic parameters and other kinematic parameters in the lower extremities, pelvis and back. 16 patients with varying degrees of deformity, scheduled for surgery within a week took part in the study. Results and conclusions: The findings have demonstrated the presence of asymmetries in kinetic parameters in the scoliotic subject and have also served to highlight the value of using kinetic and kinematic parameters in developing the understanding of the pathogenesis and aetiology of scoliosis. In addition, the results have also indicated that the variables identified in the study can be applied to initial screening and surgical evaluation of spinal deformities such as scoliosis. Further studies are being undertaken to validate these findings.
Problems and new solutions for partial discharge measurement on high voltage cables under noisy conditions (2002)

This paper reports about problems and new solutions concerning partial discharge (PD) measurement on high voltage cables under noisy conditions. In addition to the problems of PD measurement on high voltage cables in laboratories there are many problems for on-site PD measurement caused by ambient noises. Some suitable solutions according to these problems are introduced. The decoupling of the measuring signal is realized successfully with a Rogowski coil and a special cylindrical voltage sensor. A personal computer receives the digitized measuring signal and enables a digital signal processing. The necessary noise rejection is accomplished by well matched analogue coarse filters and digital filter algorithms, which suppress continuous noise signals. Experimental investigations carried out in the laboratory and on a layed cable track show the effectiveness of the presented PD measuring system under noisy conditions.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Novel High-Pressure FT-IR Spectroscopic System Combined with Specially Designed <i>In Situ</i> IR Cell for Studying Heterogeneous Catalytic Reactions (1986)

In situ spectroscopy has become increasingly important for the research of catalytic reactions over solid catalysts because of the valuable information it provides for the elucidation of the reaction mechanism under actual industrial conditions. In particular, in situ IR spectroscopy is very useful for the observation of surface species, such as adsorbed reactants, possible intermediates, and products associated with the catalytic surface reaction that have formed on the catalyst. A typical industrial process is that which involves surface reactions which are the syntheses of methanol and ammonia.
Direct Fuel Cell Stack Module Evolution (2010)

The direct carbonate fuel cell (DFC®) power plant is an emerging high efficiency, ultra-clean electric power generation system utilizing a variety of gaseous, liquid, and solid carbonaceous fuels. The power-producing block of this system is the carbonate fuel cell stack. One of its key characteristics is the ability to generate electricity directly from a hydrocarbon fuel, by reforming the fuel inside the fuel cell to produce hydrogen. FCE has placed approximately 75 units ranging from 250kW to 2.4 MW around the world, achieving an electric efficiency of 45 to 49%. FCE currently has 50 MW/year manufacturing capacity, and plans are in place to increase production capacity as demand increases from domestic and Asian markets. The manufacturing cost has been improved through implementing lean manufacturing, process improvements, and strategic sourcing for vendor purchased items. The stack output has been increased from 250kW to 350 kW. An overall stack cost reduction of ~50% has been achieved over the past five years. Concerted efforts to improve performance, lower cost and increase service life are continuing. This paper will describe FCE's DFC stack technology evolution in advancing output and lowering manufacturing cost.
Conformational studies of calix[5]arenes containing a single alkanediyl bridge † (1998)

Six new calix[5]arenes substituted at one of the methylene bridges by methyl, ethyl, isopropyl, tert-butyl, p-tolyl and p-nitrophenyl have been synthesised by heat induced (3+2) fragment condensation of a linear trimer with the corresponding bishydroxymethylated alkanediyl diphenols in boiling xylene. These conditions give the calix[5]arenes more reliably in about 20–30% yield, while the corresponding condensation with bisbromomethylated alkanediyl diphenols leads to complex mixtures from which sometimes only a calix[8]arene could be isolated. In agreement with molecular mechanics calculations the calix[5]arenes prefer the cone conformation with an equatorial position of the alkyl or aryl substituent at the bridge. From variable temperature 1H NMR spectroscopy the conformational equilibria and the energy barriers for the cone-to-cone ring inversion have been determined. Single crystal X-ray analyses have been performed for the calix[5]arene substituted by tert-butyl and for the corresponding tert-butyl substituted dinuclear precursor.
Depth of Hepatic Infiltration and Lymph Node Swelling as Factors for Considering Surgery for T2-4 Gallbladder Carcinoma Patients. (2016)

Our results suggested that ≥5 mm liver infiltration and lymph node swelling may serve as deciding factors for surgery consideration in GBC patients.
Atomic Layer Deposition of Lanthanum Stabilized Amorphous Hafnium Oxide Thin Films (2009)

Hafnium dioxide deposited on n-Si(100) by atomic layer deposition (ALD) was incorporated with La2O3 to stabilize the amorphous phase during high-temperature annealing. The incorporation of La was achieved by depositing HfO2 and La2O3 in different ALD cycles that likely produced a HfO2−HfLaxOy periodic structure. X-ray photoelectron spectroscopy compositional analysis shows that the Hf and La atomic percentage ratio can be controlled by varying the Hf and La ALD cycle ratios. Microstructure was determined with X-ray diffraction and cross-sectional transmission electron microscopy. The introduction of La increases the film crystallization temperature from 500 °C for a HfO2 film to 800, 900, and 950 °C for 10 nm films containing 13% La (metal basis), 25% La, and 43% La, respectively. The results indicate that ALD incorporating La is a potential method to grow amorphous HfO2−La2O3 high-κ dielectric thin films.
Topically applied cyclosporine in azone prolongs corneal allograft survival. (1988)

The purpose of this study was to develop and test a topical ocular delivery system for the immunosuppressive drug cyclosporine. To this end, cyclosporine was dissolved in the penetration enhancer, Azone, and applied topically to allografted rabbit eyes. The concentration of cyclosporine in the cornea, the aqueous humor, and blood of the treated rabbits was determined by radioimmunoassay. The effect of the cyclosporine-Azone preparation on the survival of corneal allografts was assessed by clinical evaluation of the grafts and by histopathologic and immunohistologic evaluation of the cellular infiltrate in the grafts. Clinically significant concentrations of cyclosporine were measured in the treated corneas but little or no drug was found in the aqueous humor or blood of the treated animals. Cyclosporine in Azone resulted in suppression in the severity and incidence of graft rejection. The suppression of graft rejection was borne out by the immunohistologic observations. Cyclosporine-treated grafts contained significantly fewer infiltrating T lymphocytes than did the drug/solvent-treated allografts, indicating that the topical application of cyclosporine actively inhibited the entry of T cells into the grafts. This study, for the first time, presents a solvent that is apparently not toxic but is effective in delivering immunologically active concentrations of cyclosporine following topical application to the cornea.
Carcinogen-induced DNA amplification in vitro: overreplication of the simian virus 40 origin region in extracts from carcinogen-treated CO60 cells. (1990)

An in vitro system to study carcinogen-induced amplification in simian virus 40 (SV40)-transformed Chinese hamster (CO60) cells is described. SV40 amplification in this system resembled in many aspects the viral overreplication observed in drug-treated CO60 cells. Cytosolic extracts from N-methyl-N'-nitro-N-nitrosoguanidine-treated cells supported de novo DNA synthesis in the presence of excess exogenous T antigen and the SV40-containing plasmid pSVK1. The pattern of viral replication in these extracts was unique, since only the 2.4-kilobase-pair region spanning the origin was overreplicated, whereas distal sequences were not replicated significantly. Extracts from control cells supported only marginal levels of replication. In HeLa extracts, complete SV40 DNA molecules were replicated efficiently. The overreplication of the origin region in CO60 cell extracts was bidirectional and symmetrical. A fraction of the newly synthesized DNA molecules underwent a second round of replication, yielding MboI-sensitive fragments representing the 2.4-kilobase-pair region around the origin. The mechanisms controlling the amplification of the viral origin region, the nature of the cellular factors induced in the carcinogen-treated cells, and their putative association with general drug-induced SOS-like responses are discussed.
Application of combined gene and cell therapy within an implantable therapeutic device for the treatment of severe haemophilia A [Abstract] (2017)

Application of combined gene and cell therapy within an implantable therapeutic device for the treatment of severe haemophilia A [Abstract]
Mobile phone based RFID architecture for secure electronic Payments using RFID credit cards (2007)

Online shopping using electronic payment scheme has gained a lot of popularity in recent years. In an electronic payment scheme using normal credit cards there is no way to genuinely identify owner of the credit card. Credit card fraud is the fastest growing crime all over the world. Any effort to plug the security hole especially for online payment is considered worthwhile. RFID enabled credit cards are becoming increasingly popular as contactless credit cards. We envision a future where RFID credit cards will be used for online shopping. RFID system has tremendous potential to render electronic payments more secure than normal credit cards. The word RFID enabled credit cards may bring in mixed passion, enthusiasm and perhaps even rage! This is partly paranoia and partly reality. The reality is that an intruder can read RFID cards without the user even noticing it. This brings in a zone of discomfort and leads to paranoia. Certain interactivity should exist to bring back this comfort to the user. This paper tries to make an effort in that direction. In this paper we propose mobile phone based architecture for secured electronic payments using RFID credit cards
Synergistic Activity of Suramin With Tumor Necrosis Factor   and Doxorubicin on Human Prostate Cancer Cell Lines (1990)

We evaluated the action of suramin, doxorubicin, and tumor necrosis factor alpha (TNF-alpha) on the testosterone-responsive human prostate cell line LNCaP and on the testosterone-independent human prostate cell line PC-3. The synergistic action of these agents in combination was tested by the Chou and Talalay method (quantitative analysis of dose-effect relationships) to determine whether in vitro doses were active at levels safely achieved in vivo. The action of suramin was potentiated threefold by doxorubicin for the PC-3 line and seven-fold by doxorubicin for the LNCaP line. Both the suramin-TNF-alpha and the doxorubicin-TNF-alpha combinations showed synergistic action against the LNCaP line. Synergistic activity was noted at drug concentrations routinely achieved clinically. This study demonstrates that suramin, doxorubicin, and TNF-alpha are active agents against prostate cancer cell lines and that their activity can be enhanced when they are used in combination.
Molecular Dynamics to Elucidate the DNA-Binding Activity of AlpZ, a Member of the Gamma-Butyrolactone Receptor Family in Streptomyces ambofaciens (2020)

Signaling molecule receptors play a central role in quorum sensing and in the coordination onset of specialized metabolite biosynthesis in <i>Streptomyces</i> due to their dual function in signal detection and gene expression control through DNA-binding in the promoter region of their target genes. In <i>Streptomyces ambofaciens</i> the <i>alp</i> biosynthetic gene cluster includes the signaling molecule receptor AlpZ that negatively regulates through a complex regulatory cascade the expression of key genes involved in the kinamycin antibiotic production until its cognate ligand, a yet unidentified signaling molecule, prompts its release from target promoters. Here we use an original molecular dynamics method to evaluate the DNA-binding properties of AlpZ to its target DNA sequence and the impact the signaling molecule has on the interaction. It is the first time this approach is used to characterize a regulator from the γ-butyrolactone receptor family. The observed K<sub>D</sub> in the nanomolar range indicates that AlpZ-DNA constitute a particularly stable complex. The signaling molecule ably disturbs this binding while kinamycin has no effect on the activity of AlpZ. Regulator size was determined and found to be considerably large regarding protein sequence, indicating that AlpZ regulates gene expression by binding the DNA as a homodimer, and structural modeling comparison with closely related γ-butyrolactone receptors supports this conclusion.
Oxidative profiling of the failing right heart in rats with pulmonary hypertension (2017)

Right heart failure is the major cause of death among patients with pulmonary arterial hypertension (PAH). Understanding the biology of the right ventricle (RV) should help developing new therapeutic strategies. Rats subjected to the injection of Sugen5416 (an inhibitors of vascular endothelial growth factor receptor) plus the ovalbumin immunization had increased pulmonary arterial pressure and severe vascular remodeling. RVs of these rats were hypertrophied and had severe cardiac fibrosis. No apoptosis was, however, detected. Metabolomics analysis revealed that oxidized glutathione, xanthine and uric acid had increased in PAH RVs, suggesting the production of reactive oxygen species by xanthine oxidase. PAH RVs were also found to have a 30-fold lower level of α-tocopherol nicotinate, consistent with oxidative stress decreasing antioxidants and also demonstrating for the first time that the nicotinate ester of vitamin E is endogenously expressed. Oxidative/nitrosative protein modifications including S-glutathionylation, S-nitrosylation and nitrotyrosine formation, but not protein carbonylation, were found to be increased in RVs of rats with PAH. Mass spectrometry identified that S-nitrosylated proteins include heat shock protein 90 and sarcoplasmic reticulum Ca2+-ATPase. These results demonstrate that RV failure is associated with the promotion of specific oxidative and nitrosative stress.
Use of atmospheric braking during Mars missions (1990)

Covers advancements in spacecraft and tactical and strategic missile systems, including subsystem design and application, mission design and analysis, materials and structures, developments in space sciences, space processing and manufacturing, space operations, and applications of space technologies to other fields.
The Effect of Kinetin on Leaf Growth (1956)

This study was intended to ascertain whether kinetin promotes a leaf growth by cell division or not, using the Raphanus leaf disks.1. The leaves showed cell enlargement without cell division by the addition of kinetin, although it has been reported as a chemical which induces cell divisions in the case of tobacco wound callus.2. It makes much increase of fresh weight and leaf area, and small of dry weight, but not total nitrogen. Its effectiveness was far greater than adenine on fresh weight and leaf area.3. The effect of kinetin was found under both light and dark conditions. 4. Without the application of IAA kinetin acted on leaf growth.5. It seemed to differ from the definition of auxin on the basis of the experiments of Avena curvature test, root test and leaf test.
Towards an Evolutionary Model of Animal-Associated Microbiomes (2011)

Second-generation sequencing technologies have granted us greater access to the diversity and genetics of microbial communities that naturally reside endo- and ecto-symbiotically with animal hosts. Substantial research has emerged describing the diversity and broader trends that exist within and between host species and their associated microbial ecosystems, yet the application of these data to our evolutionary understanding of microbiomes appears fragmented. For the most part biological perspectives are based on limited observations of oversimplified communities, while mathematical and/or computational modeling of these concepts often lack biological precedence. In recognition of this disconnect, both fields have attempted to incorporate ecological theories, although their applicability is currently a subject of debate because most ecological theories were developed based on observations of macro-organisms and their ecosystems. For the purposes of this review, we attempt to transcend the biological, ecological and computational realms, drawing on extensive literature, to forge a useful framework that can, at a minimum be built upon, but ideally will shape the hypotheses of each field as they move forward. In evaluating the top-down selection pressures that are exerted on a microbiome we find cause to warrant reconsideration of the much-maligned theory of multi-level selection and reason that complexity must be underscored by modularity.
Determination of hydroxyl groups in poly(ethylene glycols) (1979)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTDetermination of hydroxyl groups in poly(ethylene glycols)Denes F. Fritz, Araksi. Sahil, Hans Peter. Keller, and Ervin. KovatsCite this: Anal. Chem. 1979, 51, 1, 7–12Publication Date (Print):January 1, 1979Publication History Published online1 May 2002Published inissue 1 January 1979https://doi.org/10.1021/ac50037a010Request reuse permissionsArticle Views313Altmetric-Citations25LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (790 KB) Get e-Alertsclose Get e-Alerts