gebhart/patrepeval huggingface dataset:
ALDOSTERONE AND CORTISOL: IS THERE A COMMON STIMULUS IN SUBJECTS WITH RESISTANT HYPERTENSION? (2007)

Background Resistant hypertension defined as blood pressure (BP) > 140/90 mm Hg on three antihypertensive agents is a common problem. It has been reported from centers worldwide that these patients have a near 20% prevalence of primary aldosteronism (PA). The etiology of the high prevalence of hyperaldosteronism in this high-risk group is unknown. The purpose of current study is to characterize resistant hypertensive patients and identify potential stimuli of aldosterone secretion in subjects with resistant hypertension. Methods Consecutive subjects referred for resistant hypertension and control subjects with normal or mildly elevated blood pressure were prospectively evaluated with plasma aldosterone concentration (PAC), plasma renin activity (PRA), brain natriuretic peptide (BNP), atrial natriuretic peptide (ANP), and a 24-hour urine collection for aldosterone (Ualdo), creatinine, protein, cortisol (UCort), sodium (UNa), and potassium (UK) during a normal diet. All hypertensive subjects were on a stable antihypertensive regimen. Results 290 resistant hypertensive subjects and 53 controls were evaluated. Age (54.51 ± 10.83 vs 50.36 ± 10.15, p = .01), clinic BP (145 ± 21/85 ± 15 vs 125 ± 10/79 ± 7 mm Hg), PAC (13.07 ± 9.3 vs 8.44 ± 5.17 ng/dL, p = .0005), Ualdo (12.79 ± 9.98 vs 9.73 ± 6.58 μg/24 h, p = .033), BNP (41.49 ± 47.79 vs 22.48 ± 24.74 pg/mL, p = .0069), ANP (105.60 ± 76.51 vs 49.87 ± 16.65, p = .008) were higher in resistant hypertensive subjects compared with controls. BMI and waist and neck circumference were similar. A multivariate regression analysis with age, sex, race, BMI, Una, and UCort as covariates predicting aldosterone secretion shows that UCort is the strongest predictor of UAldo (p = .012). The R2 for this model is 17.4%. Subgroup analysis further showed that resistant hypertensive subjects with high UAldo (> 12 μg/24 h, n = 68), UCort (103.95 ± 40.51 vs 77.75 ± 42.94, p = .0004), UNa (200.34 ± 94.79 vs 172.96 ± 75.20 mEq/24 h, p = .0072), and UK (80.44 ± 33.79 vs 49.49 ± 20.62, p Conclusion Our findings indicate a state of hyperaldosteronism and in spite of diuretic use, persistent intravascular volume expansion evident from a high BNP and ANP values in subjects with resistant hypertension. These findings also suggest that in these subjects, there may be a common stimulus for cortisol and aldosterone such as ACTH, other stimuli being dietary sodium and/or dietary potassium.
Motion Control of Passive-Type Intelligent Walker Based on Caster-Like Dynamics (2005)

The goal of this research is to develop an intelligent walker which is the passive-type walker referred to as RT Walker. In this paper, especially, we propose a motion control algorithm referred to as adaptive caster action to utilize RT Walker with good maneuverability in an environment such as a home, an office, a hospital, etc. The proposed control algorithm is experimentally applied to RT Walker, and the validity of the proposed control algorithm is illustrated by the experimental results.
Growth and yield of shortleaf pine (1986)

A survey of available growth and yield information for shortleaf pine (Pinus echinata Mill.) is given. The kinds of studies and data sources that produce this information are also evaluated, and an example of how a growth and yield model can be used to answer management questions is illustrated. Guidelines are given for using growth and yield models, and needs for further research are outlined.
Grain size effects on electromigration liftetime [sic] and drift velocity of Al-Si-Cu/TiNO/TiSi₂ (1995)

Al .50%Si .75%Cu on TiNO / TiSi 2 / n+contact windows were fabricated with the AI-Cu-Si deposited at various temperatures between 25 400C in an attempt to intentionally vary the grain size of the aluminum metallization. The grain size distribution at each temperature was then characterized in order to determine the effect of the grain size on the electromigration performance of the contacts. The median grain size increased up to 300 C and then decreased at the highest deposition temperature. Electromigration measurements performed on each sample showed that the median time to failure steadily increased with increasing metal deposition temperature. Additional experiments were done to determine Q, the thermal activation energy, and n, the current density exponent from Black's equation. Q was determined to be 1.21 eV and n was found to be 1.41 with neither value showing any significant dependence on the grain size of the metal. The drift velocity of the AI was also measured along with the thermal activation energy for drift. The drift velocity showed a stronger dependence on the deposition temperature than on the grain size which was not expected. The thermal activation energy for drift was calculated to be 0.75 0.80 eV at the lower deposition temperatures and 1.00 1.05 eV at the higher deposition temperatures. This ./ corresponds to an increasing contribution from lattice diffusion versus grain boundary diffusion at the higher deposition temperatures. The improvement in the mean time to failure with increasingdeposition temperature is due to the decreasing drift velocity and the increased thermal activation energy for drift. Diffusion of Ti from the TiN layer at the 400°C deposition temperature is used as the possible explanation for these effects as well as the decreased grain size.
Caustic surfaces and the structure of the geometrical image (1976)

A general solution of the eikonal equation is used to derive general expressions for both the wave fronts and the caustic surface associated with an orthotomic system of rays in a homogeneous optical medium. Both wave front and caustic can be expressed as the sum of two vectors, the first being the direction vector of the ray and the second being the gradient of the arbitrary function occurring in the general solution of the eikonal equation. This vector can be determined from a knowledge of the angle characteristic function and is closely related to Herzberger’s diapoint characterization of the geometrical image.
Alternating π‐conjugated copolymer of dithiafulvene with 2,2′‐bipyridyl units (2001)

Abstract A π‐conjugated polymer containing a dithiafulvene unit and a bipyridyl unit was prepared by cycloaddition polymerization of aldothioketene derived from 5,5′‐diethynyl‐2,2′‐bipyridine. Ultraviolet–visible (UV–vis) absorption spectra showed that the π‐conjugation system of the polymer expanded more effectively than that of a benzene analogue of poly(dithiafulvene) obtained from 1,4‐diethynylbenzene. Cyclic voltammetry measurements indicated that the dithiafulvene–bipyridyl polymer was a weaker electron‐donor polymer than the benzene analogue. These results supported the idea that the incorporation of the electron‐accepting bipyridyl moiety into conjugated poly(dithiafulvene) induced an intramolecular charge‐transfer (CT) effect between the units. Treatment of the dithiafulvene–bipyridyl polymer with bis(2,2′‐bipyridyl)dichlororuthenium (II) [Ru(bpy) 2 Cl 2 ] afforded a ruthenium–polymer complex. A cyclic voltammogram of the complex showed broad redox peaks, which indicated electronic interaction between the dithiafulvene and tris(bipyridyl) ruthenium complex. The dithiafulvene–bipyridyl polymer formed CT complexes with 7,7,8,8‐tetracycanoquinodimethane (TCNQ) in dimethyl sulfoxide. The UV–vis absorption indicated that the resulting CT complex contained anion radical of TCNQ and partially charge‐transferred TCNQ. The polymer showed an unusually high electrical conductivity of 3.1 × 10 −4 S/cm in its nondoped state due to the effective donor–acceptor interaction between the bipyridine unit and the dithiafulvene unit. © 2001 John Wiley & Sons, Inc. J Polym Sci Part A: Polym Chem 39: 4083–4090, 2001
Broughton, Rhoda, [1890-1891] March 6 (1890)

written from 34 De Vere Gardens, I am sadly disappointed . . . ; redated from [n.y.] 12/8/10 RDS
Secure supply-chain protocols (2003)

Supply chain interactions have huge economic importance, yet these interactions are managed inefficiently. One of the major sources of inefficiency in supply-chain management is information asymmetry; i.e., information that is available to one or more organizations in the chain (e.g., manufacturer, retailer) is not available to others. There are several causes of information asymmetry, among them fear that a powerful buyer or supplier will take advantage of private information, that information will leak to a competitor, etc. We propose secure supply-chain collaboration (SSCC) protocols that enable supply-chain partners to cooperatively achieve desired system-wide goals without revealing the private information of any of the parties, even though the jointly computed decisions require the information of all the parties. Secure supply-chain collaboration has the potential to improve supply-chain management practice, and by removing a major inefficiency therein, improves productivity. We present specific SSCC protocols for two types of supply-chain interactions: capacity allocation, and e-auctions (electronic auctions). In the course of doing so, we design techniques that are of independent interest, and are likely to be useful in the design of future SSCC protocols.
Management of Potato Leafhopper,Empoasca fabae(Homoptera: Cicadellidae), on Alfalfa with the Aid of Systems Analysis (1984)

Journal Article Management of Potato Leafhopper, Empoasca fabae (Homoptera: Cicadellidae), on Alfalfa with the Aid of Systems Analysis Get access David W. Onstad, David W. Onstad 1 Department of Environmental Engineering, Hollister Hall, Cornell University, Ithaca, New York 14853 1 Current address: Dept. of Entomology, N.Y. State Agric. Exp. Stn., Geneva, NY 14456. Search for other works by this author on: Oxford Academic PubMed Google Scholar Christine A. Shoemaker, Christine A. Shoemaker Department of Environmental Engineering, Hollister Hall, Cornell University, Ithaca, New York 14853 Search for other works by this author on: Oxford Academic PubMed Google Scholar Beth C. Hansen Beth C. Hansen Department of Environmental Engineering, Hollister Hall, Cornell University, Ithaca, New York 14853 Search for other works by this author on: Oxford Academic PubMed Google Scholar Environmental Entomology, Volume 13, Issue 4, 1 August 1984, Pages 1046–1058, https://doi.org/10.1093/ee/13.4.1046 Published: 01 August 1984 Article history Received: 05 October 1983 Accepted: 23 April 1984 Published: 01 August 1984
COSAR (2003)

Microelectronic manufacturing is a discipline of supply chain management, and deals with the efficient coordination of manufacturing processes and owning enterprise along a value chine to provide products to customers. The systems for microelectronic manufacturing processes are usually linear, rigid and producing solutions that are far from optimal. This paper presents a commitment-oriented "sense and respond" system, called COSAR, for microelectronic manufacturing. COSAR enables the development of adaptive and configurable manufacturing systems. We will explain both the concept of commitment and also the foundation and architecture of COSAR.
Eigenschaften von Natrium‐α‐sulfo‐fettsäuremethylestern (1970)

Abstract An Hand von Messungen der Leitfähigkeit, der Oberflächenspannung, der Solubilisierung von Farbstoffen, der Löslichkeit, der Krafft‐Punkte, der Schmelzpunkte, der Benetzung von Polyäthylen, der Emulgierwirkung für Öle und des Waschvermögens wird ein Vergleich der Eigenschaften von Natrium‐α‐sulfo‐fettsäuremethylestern und Natrium‐n‐alkylsulfaten durchgeführt. Die Änderung der Eigenschaften wird in Abhängigkeit von der Zahl der Kohlenstoffatome im hydrophoben Rest und dem Charakter der hydrophilen Gruppe diskutiert.
A Three-Dimensional Time-Varying Channel Model for 5G Indoor Dual-Mobility Channels (2017)

This paper presents a time-varying channel model in three- dimensional environments for the 5G wireless system. Using the continuous-time Markov chain, the proposed model captures the statistical movement of the transceiver, the transition between line-of-sight and non-line-of-sight propagation scenarios, and the dynamic variation of propagation parameters. Moreover, a novel frequency- dependent factor that describes the dynamic path behavior is described in this model. According to the simulation results based on ray-tracing techniques and field measurements from the literature, the proposed time- varying channel model is validated at 5.2, 10, and 60 GHz. Furthermore, under realistic 5G device-to-device communication scenario, the simulation results and time- varying channel characteristics are highlighted, including the number of paths, path gain, delay spread, delay variation, Rician K-factor, and coherence bandwidth.
Discovery of Low-Molecular Weight Antagonists of Substance P: Recent Developments and Prospects as a Therapeutic Agent. (1994)

The creation of antagonists of substance P (SP) has been the focus of intensive research because of their potential as therapeutic agents. A conventional for an SP antagonist is the synthesis of SP analogs in which amino acids are substituted or some peptide bonds are modified. Another useful method is the screening of compounds from a sample file. This method, called random screening, led to the discovery of novel and potent non-peptide antagonists. Apart from these two strategies, we were able to design low-molecular weight antagonists from a known peptide lead. The search for the essential part for receptor binding, improvement of the stability against enzymatic metabolism, and chemical modifications led to a potent tripeptide (4, FR 113680). The molecular size of this tripeptide was reduced to a dipeptide structure such as 13, through newly designed branched tripeptides (510). Further optimization of the lysine part of 13 into (2 S, 4 R) Hyp and subsequent modification of the side chain parts culminated in the potent dipeptide antagonist (15, FK 888). The pharmacological profile of 15 as an antiasthma agent is also presented.
Insulin Is Released from Rat Brain Neuronal Cells in Culture (1986)

Depolarization of neuronal cells in primary culture from the rat brain by potassium ions in the presence of calcium or by veratridine caused a greater than three-fold stimulation of release of immunoreactive insulin. HPLC of the released insulin immunoreactivity from the neuronal cultures comigrated with the two rat insulins. The depolarization-induced release of insulin was inhibited by cycloheximide and was specific for neuronal cultures since potassium ions failed to cause the release in comparably prepared astrocytic glial cells from the rat brain. Prelabelling of neuronal cultures with [3H]leucine followed by depolarization resulted in the release of radioactivity that immunoprecipitated with insulin antibody. The release of [3H]insulin was biphasic. These observations suggest that neuronal cells from the brain have the capacity to synthesize insulin that could be released under depolarization conditions.
InstantApps: A WYSIWYG model driven interpreter for web applications (2009)

We describe InstantApps, a WYSIWIG, model driven interpreter for developing and running web based database oriented applications. Applications are dynamically rendered through efficient runtime interpretation of meta-data which is manipulated through an intuitive visual designer. We also capture complex (multi-table) forms, workflow as well as business logic (using a variant of Google's MapReduce abstraction), distinguishing our approach from similar platforms in the literature as well as others recently made available on the Internet.
Cramer-Rao bounds for time reversal mimo radars with multipath (2016)

The paper derives closed-form expressions of the deterministic Cramer-Rao bound (CRB) bounds for the direction of arrival (DOA) and Doppler frequency of a moving target in a multipath environment for both conventional multiple-input multiple-output (MIMO) and time reversal (TR) MIMO frameworks. Incorporating the adaptive TR waveform processing feature in the MIMO radars improves the TR CRBs in ways not seen with conventional MIMO. The TR/MIMO framework provides CRB gains of up to 15 dB in a 3-path environment.
Use of full-waveform sonic data to image near-borehole structural features (1995)

The full waveforms recorded by an array of receivers in a modern full-waveform sonic tool contain secondary arrivals that are reflected from near-borehole structural features. These arrivals are used to form an image of the near-borehole structural features in a manner similar to seismic migration. Possible uses of this technique include horizontal well logging; structural dip and contour determination; fault, salt dome, pinnacle reef, and fracture zone imaging; and EOR steam-flood monitoring. Examples are given for a deviated well penetrating a North Sea reservoir, and for a horizontal well penetrating a thin (10m thick) reservoir. For the horizontal well case, full-waveform sonic data are successfully used to image the reservoir top as the well penetrates into the reservoir and continues near-parallel to the reservoir boundary.
Effects of Defoliation, Bud Removal and Girdling Treatments on Sprouting of Quercus acutissima Carr. (1992)

Effects of defoliation, bud removal and girdling treatments on sprouting in adult trees and seedlings of @ercus acutissima Carr. were investigated in order to clarify the mechanism of sprouting and the ecological significance of sprouts. Both in adult trees and seedlings, sprouts flushed below the positions of girdling. In seedling experiments, numerous sprouts also flushed in bud removal treatment. These results suggest that inhibitors of sprouting, formed in terminal or axillary buds, are translocated through phloem, thereby inhibiting sprouting from suppressed buds. In defoliation treatments, seedlings flushed new shoots from current axillary buds after treatment, although only a few sprouts flushed. As a consequence, a shortage of photosynthetic organs were not assumed to be directly related to sprouting. From these results, it is suggested that trees recover their assimilative architecture by flushing new shoots from current terminal or axillary buds when they lose foliage as a result of disturbance such as predation. On the other hand, sprouts flushed from suppressed buds are thought to contribute to the recovery of canopy caps or the maintenance of seedlings when the growth points on upper sections are lost due to disturbance. It is also suggested that differences in sprouting vigor caused by age, size and species should be discussed in relation to the balance between inhibition from terminal or axillary buds, and stimulation from lower parts of plants.
Practical Flow Cytometry, 4th Edition (2003)

Practical Flow Cytometry, 4th Edition Author: Howard Shapiro Bibliographic Data: John Wiley & Sons, Inc., 2003. ISBN: 0-471-41125-6, 681 pp, hard cover, $119.00. Reviewer's Expert Opinion: Description: This is a truly comprehensive book on everything you could ever want to know about flow cytometry. Purpose: The purpose of this book is to be THE reference book on flow cytometry. This is the fourth edition of this book, and there is no question that it is THE reference book on flow cytometry! Audience: This book would be useful to anyone who uses flow cytometry or relies on this technology for their research or clinical care. Features: This book continues in its grand tradition of being the “bible” of flow cytometry. I cannot adequately describe its depth and breadth, so I resort to sheer astounding numbers to portray its comprehensiveness—566 pages of 10 point font, surprisingly few illustrations (yes, it's primarily text), 3,685(!) references. In briefly skimming the book, I was overwhelmed by the massive amount of information. No question that I'll have this book within easy reach whenever I field questions about flow cytometry! A really nice touch in this book is the author's chatty (and sometimes quirky) writing style. The reader will not only find accurate and complete factual information, but will also appreciate flow cytometry-themed lyrics to sing to the tune for famous melodies, Shapiro's various (and amusing) laws, and helpful tips (including the final one that warns the user to never use a staff to smite a clogged cytometer). The author's humor and conversational style makes interesting reading and the information incredibly accessible. A major difference between this and the third edition is the elimination of the section on the “do-it-yourself” flow cytometer (e.g., “cytomutt”)—the author's acknowledgement of the widespread penetration of commercial systems in the field. In this regard, there is a very helpful chapter listing the various manufacturers and companies from which reagents can be purchased. Finally—and rare in these types of comprehensive books—there is touching recognition to those who were pioneers in this field. A really nice human touch to a very complex subject. Assessment: Wow! You need this book if you use flow cytometry. Get it!
Low-Temperature Oxidation-Free Selective Laser Sintering of Cu Nanoparticle Paste on a Polymer Substrate for the Flexible Touch Panel Applications (2016)

Copper nanomaterials suffer from severe oxidation problem despite the huge cost effectiveness. The effect of two different processes for conventional tube furnace heating and selective laser sintering on copper nanoparticle paste is compared in the aspects of chemical, electrical and surface morphology. The thermal behavior of the copper thin films by furnace and laser is compared by SEM, XRD, FT-IR, and XPS analysis. The selective laser sintering process ensures low annealing temperature, fast processing speed with remarkable oxidation suppression even in air environment while conventional tube furnace heating experiences moderate oxidation even in Ar environment. Moreover, the laser-sintered copper nanoparticle thin film shows good electrical property and reduced oxidation than conventional thermal heating process. Consequently, the proposed selective laser sintering process can be compatible with plastic substrate for copper based flexible electronics applications.
Aminobenzofuran-Fused Rhodamine Dyes with Deep-Red to Near-Infrared Emission for Biological Applications (2015)

Aminobenzofuran-fused rhodamine dyes (AFR dyes) containing an amino group were constructed by an efficient condensation based on 3-coumaranone derivatives. AFR dyes exhibited significantly improved properties, including deep-red and near-infrared emissions, a large Stokes shift, good photostability, and wide pH stability. 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazolium assay experiments show that these AFR dyes are biocompatible for their low cytotoxicity to both A549 and HeLa cells. Cell imaging data reveal that AFR1, AFR1E, and AFR2 are mainly located in the mitochondria, while AFR3 is a lysosome tracker. As far as we know, NIR AFR3 is the longest fluorescent rhodamine derivative containing the amino group. These amino group-containing AFR dyes hold great potential in fluorogenic detection, biomolecule labeling, and cell imaging.