gebhart/patrepeval huggingface dataset:
Approaches to Polymer Compounding (1960)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTApproaches to Polymer CompoundingC. A. Uraneck and R. J. SonnenfeldCite this: Ind. Eng. Chem. 1960, 52, 9, 790–794Publication Date (Print):September 1, 1960Publication History Published online1 May 2002Published inissue 1 September 1960https://pubs.acs.org/doi/10.1021/ie50609a033https://doi.org/10.1021/ie50609a033research-articleACS PublicationsRequest reuse permissionsArticle Views46Altmetric-Citations2LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Identification of a putative shared epitope between Coxsackie virus B4 and alpha cardiac myosin heavy chain (1991)

Molecular mimicry is an important postulated mechanism for autoimmunity in viral myocarditis. The 356-1 monoclonal antibody neutralizes Coxsackie virus B4 by binding to the VP1 protein and cross-reacts with mouse alpha cardiac myosin heavy chain. We used this monoclonal antibody to screen a lambda gt11 expression library made from CD-1 mouse hearts. Of the 48 positive plaques/10(6) recombinant phages examined, 14 of the strongest-reacting clones were purified for additional studies. The inserts were amplified by polymerase chain reaction and the amplified products ranged from about 150 to 1400 bp in size. Northern hybridization using these inserts demonstrated that 11 out of 14 reacted with a message equivalent to that of cardiac myosin in size. Additional Southern hybridization studies suggested that these 11 inserts contained overlapping sequences in the light meromyosin fragment of cardiac myosin. Sequence analysis confirmed that these 11 independent, recombinant clones contained a common sequence representing amino acid residues 1299-1647. Within this fragment only one isoform-specific site matched the observed reactivity pattern of 356-1 among hearts from various species. Thus, we were able to identify a putative shared epitope represented by residues 1632-1647.
Raman and infrared spectra of BF/sub 3/ complexes with diethyl ether and tetrahydrofuran, and the isotopic exchange of these complexes with BF/sub 3/ (1963)

The Raman and infrared spectra of BF/sub 3/.diethyl ether and BF/sub 3/.tetrahydrofuran were recorded for both the B/sup 10/ and B/sup 11/ compounds. The spectra were compared to that of BF/sub 3/.dimethyl ether and tentative assignments of the skeletal vibrations were made. The isotopic data were used to calculate theoretical equilibrium constants for isotopic exchange between the complexes and BF/sub 3/. The calculated values are slightly higher but compare quite well with published values of experimentally determined separation factors.
A Study on the Thermal Crack Resistivity of the Cutting Tool (1st Report) (1987)

Transient cutting temperature in interrupt cutting has been studied with the aim to evaluate the thermal crack resistivity of the cutting tool materials. Transient temperature distribution inside the tool, which governs thermal stresses and consequently thermal cracks, has been theoretically analyzed and formulated to the simple algebraic equation. The calculated transient temperatures of the tool surface by this equation have the good agreements with those obtained experimentally.
AN AUTOMATIC FILTER-WASHER. (1901)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAN AUTOMATIC FILTER-WASHER.J. M. PickelCite this: J. Am. Chem. Soc. 1901, 23, 8, 589–593Publication Date (Print):August 1, 1901Publication History Published online1 May 2002Published inissue 1 August 1901https://pubs.acs.org/doi/10.1021/ja02034a005https://doi.org/10.1021/ja02034a005research-articleACS PublicationsRequest reuse permissionsArticle Views23Altmetric-Citations2LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Performance analysis of transistor-based circuits through TAMAMS Web: From bulk to molecular devices (2016)

To meet the challenges associated with transistor scaling and short channel devices, the structure of MOS devices has undergone an incredible evolution. From Bulk devices, technology has shifted through Silicon-On-Insulator (SOI) devices, reaching now FinFET transistors, the next steps in the evolutionary path are represented by Gate-All-Around (GAA) and Molecular Transistors. Using analytical compact models for standard (BULK, SOI, FinFET) and emerging devices (GAA, Molecular FET (MOLFET)), it is possible to predict the system level performance of future NANO electronic circuits. In this work, we show how circuit's performance can be predicted and analyzed at system level using our tool, TAMTAMS Web. Starting from Bulk transistors down to a nanometer scale Molecular FET, TAMTAMS Web incorporates models to analyze device quantities (Drive current, Subthresold current...) up to system level. We have developed a compact model of Virtex 4 FPGA CLB block that is used as benchmark. The work here presented not only highlights the potentialities of TAMTAMS, but it also provides useful hints on the evolution of transistor based technology.
On the functional relationship between <sup>45</sup>Ca<sup>2+</sup> release and prolactin secretion in cultured rat pituitary tumour (GH<sub>3</sub>) cells (1986)

We have evaluated the role of cellular Ca2+ transport associated with stimulus-secretion coupling in prolactin (PRL) producing rat pituitary adenoma cells (GH3 cells). The action of different substances, known to modify PRL secretion, on release of 45Ca2+ from preloaded cells were examined. Surface-bound 45Ca2+ was removed by pretreatment with trypsin in EDTA buffer. During the first 6 min, basal efflux of 45Ca2+ occurred at a constant rate (0.24 min-1) at 37 degrees C. Addition of TRH (5 X 10(-7) M) resulted in an immediate enhancement of 45Ca2+ release representing about 20% of the remaining cellular 45Ca2+. In the same experiments PRL secretion increased by 45%. The EDTA in the external medium reduced the basal rate of 45Ca2+ release by 60%, but did not apparently affect the TRH-stimulated release. Somatostatin (10(-6) M) and verapamil (5 X 10(-5) M) inhibited both basal and TRH-stimulated PRL secretion, whereas high extracellular concentration of K+ (5 X 10(-2) M) had a stimulatory effect. However, neither of these treatments changed cellular 45Ca2+ release. Interference with energy-dependent Ca2+ transport by using metabolic inhibitors (iodoacetate, 6 X 10(-3) M; and antimycin, 2 X 10(-6) M) or by replacing Na+ in the medium by choline or by lowering the incubation temperature from 37 to 25 degrees C, had no effect on TRH-stimulated 45Ca2+ release although basal and TRH-stimulated PRL secretion were reduced. Thus, TRH apparently releases 45Ca2+ from calcium binding sites in the cell membrane.
Stress-Induced Sphingolipid Signaling: Role of Type-2 Neutral Sphingomyelinase in Murine Cell Apoptosis and Proliferation (2010)

nSMase2 activation is not involved in apoptosis mediated by TNFalpha and oxidized LDLs in murine fibroblasts, and in the hepatotoxicity of TNFalpha in mice, but is required for the mitogenic response to stress-inducing agents.
Humoral immune response against human cytomegalovirus (HCMV)-specific proteins after HCMV infection in lung transplantation as detected with recombinant and naturally occurring proteins (1995)

The humoral immune response to four intracellularly located cytomegalovirus (CMV) proteins was studied in 15 lung transplant recipients experiencing active CMV infections. Five patients had primary infections, and 10 had secondary infections. Antibodies of the immunoglobulin M (IgM) and IgG classes were measured in an enzyme-linked immunosorbent assay (ELISA) system in which procaryotically expressed recombinant proteins were used as a substrate and also in a monoclonal antibody-based capture ELISA which uses naturally occurring proteins as a substrate. The proteins investigated were the lower matrix protein pp65 (ppUL83), the major DNA-binding protein p52 (ppUL44), and the two immediate early proteins IE1 and IE2 (different splicing products of UL123). Higher levels of antibodies were found to pp65 and especially to p52 than to the immediate early antigens. Antibody levels detected in the recombinant protein-based ELISAs were generally lower than antibody responses detected with the matching antigen capture ELISA. Moreover, some patients appeared to have antibodies mainly to epitopes present on naturally occurring proteins. The antibody responses detected in both assays were related to the viral load during infection as assessed by the CMV antigenemia test, which is a quantitative marker for CMV load. It was found that although epitopes on naturally occurring proteins induce higher antibody responses and responses in more patients, antibodies directed to epitopes present on the recombinant proteins were inversely related to the viral load during a CMV infection. Therefore, antibodies to epitopes on the recombinant proteins might be more clinically relevant in this group of lung transplant recipients.
Bronchogenic Carcinoma After Lung Transplantation (2002)

Collins, Jannette M.D., M.Ed., F.C.C.P.; Kazerooni, Ella A. M.D.; Lacomis, Joan M.D.Author Information
New Developments in Serodiagnosis of Childhood Celiac Disease (2009)

Antibodies to deamidated gliadin present a new tool in the diagnosis of celiac disease (CD). In children, the ELISA for the determination of IgG antibodies to (deamidated) gliadin-analogous fusion peptides (GAF3X) has a superior performance compared to the ELISA for the determination of antibodies against native gliadin and is comparable to assays for IgA antibodies against tissue transglutaminase (IgA-anti-tTG). The combined investigation of IgG antibodies to GAF3X (IgG-anti-GAF3X) and IgA-anti-tTG significantly increases the fraction of children definitely identified as either CD or non-CD patients. The new IgG-anti-GAF3X ELISA was also able to detect CD in three cases of IgA deficiency and in two cases of latent CD and was also useful in the diagnosis of children younger than 2 years of age.
Cutaneous Vasoconstriction Contributes to Hyperthermia Induced by 3,4-Methylenedioxymethamphetamine (Ecstasy) in Conscious Rabbits (2001)

3,4-Methylenedioxymethamphetamine (MDMA; "Ecstasy") increases body temperature. This process could be associated with increased cutaneous blood flow, as normally occurs with exercise-induced hyperthermia. Alternatively, an MDMA-induced fall in cutaneous blood flow could contribute to the hyperthermia by diminishing normal heat transfer from the body to the environment. We investigated these possibilities by administering MDMA (1.5-6 mg/kg, i.v.) to conscious freely moving rabbits, determining effects on body temperature, cutaneous blood flow (measured by a Doppler ultrasonic probe that was chronically implanted around the ear pinna artery), and other cardiovascular parameters. MDMA caused a dose-dependent increase in body temperature (from 38.3 +/- 0.3 to 41.2 +/- 0.4 degrees C after 6 mg/kg; p < 0.01; n = 5), preceded and accompanied by a dose-dependent cutaneous vasoconstriction (from 29 +/- 6 to 5 +/- 1 cm/sec after 6 mg/kg; p < 0.01; n = 5). MDMA (3 mg/kg) did not change blood flow to the mesenteric vascular bed. Prior unilateral cervical sympathectomy reduced the increase in body temperature elicited by MDMA (6 mg/kg) from 2.0 +/- 0.2 to 1.3 +/- 0.2 degrees C (p < 0.01; n = 5). On the denervated side, ear pinna blood flow after MDMA injection was 13 +/- 3 cm/sec, compared with 3 +/- 1 cm/sec on the sympathetically intact side (p < 0.05; n = 5). Thus, sympathetically mediated cutaneous vasoconstriction is one mechanism whereby MDMA causes hyperthermia. Reversal of cutaneous vasoconstriction by appropriate pharmacological means could be of therapeutic benefit in humans suffering from life-threatening hyperthermia induced by MDMA.
Abstract 147: Cell Selective Cardiovascular Biology of mPGES-1 (2012)

Background— Global deletion of mPGES-1 attenuates the response to vascular injury without increasing predisposition to thrombogenesis or hypertension. However, enzyme deletion results in cell specific differential utilization of accumulated substrate. Here, we generated mice deficient in mPGES-1 in vascular smooth muscle cells (VSMC), endothelial cells (ECs) and myeloid cells to further elucidate the cell selective roles of this enzyme in cardiovascular biology. Results— VSMC and EC mPGES-1 deficient mice were generated by mating mPGES-1 flox/flox mice with SM22Cre or Tie2Cre mice respectively. Blood pressure was unaltered in these mutants at baseline or in response to a high salt diet. The propensity to induced thrombogenesis in a microvascular preparation was similarly unaltered. By contrast, both mPGES-1 flox/flox SM22Cre and mPGES-1 flox/flox Tie2Cre mice exhibited a markedly exaggerated neointimal hyperplastic response to wire injury of the femoral artery compared to their mPGES-1 flox/flox littermate controls (intima to media ratio 4.36 ± 0.63, 3.27 ± 0.23 versus 2.04 ± 0.31, p<0.01, n=8-13). The severity of neointimal hyperplasia was associated with increased proliferating cell nuclear antigen (PCNA) and tenascin-C (TN-C) expression. Macrophage mPGES-1 deficient mice (Mac-mPGES-1-KO) were generated by mating mPGES-1 flox/flox mice with LysMCre mice. In these mice, the hyperplastic response to vascular injury was dramatically suppressed (intima to media ratio 2.59 ± 0.18 versus 1.47 ± 0.25, p<0.01, n=10) as was the expression of PCNA and TN-C. In vitro, conditioned medium derived from LPS-primed Mac-mPGES-1-KO macrophages was less potent than that from Mac-mPGES-1-WT macrophages in inducing VSMC proliferation and migration. Conclusions— Deletion of mPGES-1 in vascular vs. myeloid cells results in contrasting vascular phenotypes. While enzyme knocked out in vascular cells does not augment thrombosis or predispose to hypertension, EC and VSMC mPGES-1 restrains the response to vascular injury. mPGES-1 in myeloid cells, by contrast, promotes the response to vascular injury and represents a potential therapeutic target.
Zygodon (Orthotrichaceae) in the Iberian Peninsula (2008)

The genus Zygodon in the Iberian Peninsula is revised and six species are recognized: Zygodon catarinoi, Z. conoideus, Z. forsteri, Z. rupestris, Z. stirtonii and Z. viridissimus. A key, descriptions, illustrations and maps of each taxon are given. Zygodon stirtonii is reported for the Iberian Peninsula for the first time. Zygodon catarinoi and Z. bistratus are conspecific, and the former predates Z. bistratus by two days.
Facilitated transport of pertechnetate across Supported Liquid Membranes (SLMs) (1995)

This summary describes modeling and laboratory work examining the feasibility of extracting technetium 99 from US Department of Energy tank wastes in supported liquid membranes (SLMs) using crown ethers as extractants. SLMs consist of a solvent contained in the pores of a polymeric membrane between two aqueous solutions (feed and strip). Crown ethers form a complex with sodium and technetium at the extraction interface. This complex diffuses across the membrane and is then stripped at the strip interface.
Successful Treatment of Pyoderma Gangrenosum Associated with Myelodysplastic Syndrome Using High-Dose Intravenous Immunoglobulin (2008)

We report the case of a 61-year-old man with pyoderma gangrenosum (PG) who was successfully treated with high-dose intravenous immunoglobulin (IVIg). He was transported to hospital with fever, pain and ulcer of the left inner thigh, and pancytopenia. PG associated with myelodysplastic syndrome was diagnosed, and treatment with methyl-prednisolone at 1.0 g/day for 3 days was followed by oral prednisolone. As the ulcer deteriorated when prednisolone dose was reduced, he was admitted to our hospital. IVIg was administered twice, with high fever promptly subsiding and the ulcer markedly decreasing in size. IVIg may represent a good option when steroid therapy proves insufficient.
Pulse radiolysis of benzyl chloride and ‐bromide; The UV‐visible absorption spectrum of the benzyl cation (1994)

Abstract Pulse radiolysis study of liquid benzyl chloride has been carried out at room temperature. In order to identify transient species that absorb in the UV‐vis region, various scavengers were used including oxygen, ethanol, pyrrole, biphenyl, and mesitylene (1,3,5‐trimethylbenzene). The spectrum of the benzyl cation was obtained by subtracting the transient spectrum for the 0.6 M solutions of ethanol in O 2 ‐saturated benzyl chloride from that for O 2 ‐saturated benzyl chloride. The difference spectrum obtained has a strong absorption band at 303±2 nm and a weak broad band near 500 nm. The analyses of end products formed in the γ radiolysis of benzyl chloride were done in the presence and absence of scavengers. The formation of benzyl ethyl ether with a G value of 0.9 from a 0.6 M solution of ethanol in O 2 ‐saturated benzyl chloride was taken as evidence that added ethanol reacts with benzyl cations to give benzyl ethyl ether. Some pulse radiolysis experiments were performed with benzyl bromide. Transient spectra observed in benzyl bromide are similar to those observed in benzyl chloride. It is, however, inferred from the product analysis that the radiolytic mechanisms of benzyl bromide appreciably differ from those of benzyl chloride.
Electrically pumped room-temperature operation of GaAs<sub>1−</sub><i><sub>x</sub></i>Bi<i><sub>x</sub></i>laser diodes with low-temperature dependence of oscillation wavelength (2014)

Lasing oscillation at wavelengths up to 1045 nm at room temperature has been realized from GaAs1−xBix Fabry–Perot laser diodes (FP-LDs) by electrical injection, and the temperature characteristics of GaAs1−xBix FP-LDs are revealed for the first time. The characteristic temperature T0 of the GaAs0.97Bi0.03 FP-LD in the temperature range between 15 and 40 °C (T0 = 125 K) is similar to that reported for typical 0.98 µm InGaAs/GaAs LDs. The temperature coefficient of the lasing wavelength in GaAs0.97Bi0.03 FP-LDs is reduced to 0.17 nm/K, which is only 45% of that of GaAs FP-LDs.
Session T3D Mobile Laboratory Programs as Vehicles to Promote STEM Education in K-12 and Beyond (2013)

Abstract- Mobile laboratories refer to self-contained, traveling laboratories that accommodate student participation in hands-on laboratory science aboard the mobile laboratory unit. Most of the mobile laboratory programs that are now in operation focus on providing middle and high school students and teachers with access to science equipment and supplies that are difficult for them to acquire and maintain. In addition, many of the mobile laboratory programs provide inquiry-based curricular materials that are engaging, substantive, and thought provoking. Further, since mobile laboratories are completely self-sustained and can travel to urban and rural locations that are often educationally and economically disadvantaged, they provide equal access to state-of the art learning opportunities. The use of mobile laboratories is an innovative way to transform science teaching and learning, particularly in the pre-college setting. While many of the mobile laboratory programs now in operation focus on the biological sciences, we believe that these programs can be adapted to broader applications in STEM education. Mobile laboratories have the potential to offer powerful and unique ways to engage and inspire future scientists and engineers. These “vehicles ” may pique the curiosity of students and motivate them to continue their study of science in high school and beyond. As such, mobile science laboratories may contribute to increasing the number of students who become science-literate citizens and members of the science workforce.
Recent Resurgence of Mumps in the United States (2008)

Despite a high coverage rate with two doses of mumps-containing vaccine, a large mumps outbreak occurred, characterized by two-dose vaccine failure, particularly among midwestern college-age adults who probably received the second dose as schoolchildren. A more effective mumps vaccine or changes in vaccine policy may be needed to avert future outbreaks and achieve the elimination of mumps.
Investigation and reduction of line frequency common mode voltages at the outputs of AC/DC power converters (2017)

Although existing standards such as IEC62684 and EN 301 489-34 limit the line frequency common mode (CM) voltages at the output of AC/DC converters, the mechanism and characteristics of line frequency CM voltages at the outputs of AC/DC converters are unclear and the technique to reduce it is not well investigated and developed. In this paper, the line frequency CM voltages at the outputs of AC/DC converters are analyzed and a modeling technique is developed. Simulations and experiments were conducted to validate the developed technique. An AC/DC Flyback converter is taken as a study example. The paper also analyzed the effect of the start-up circuit at the primary side on the CM voltages. The relationship between leakage current and CM voltage is also discussed. The techniques to reduce the output line frequency CM voltages is also investigated and developed.
Feasibility Theory Reconciles and Informs Alternative Approaches to Neuromuscular Control (2018)

We present Feasibility Theory, a conceptual and computational framework to unify today's theories of neuromuscular control. We begin by describing how the musculoskeletal anatomy of the limb, the need to control individual tendons, and the physics of a motor task uniquely specify the family of all valid muscle activations that accomplish it (its 'feasible activation space'). For our example of producing static force with a finger driven by seven muscles, computational geometry characterizes-in a complete way-the structure of feasible activation spaces as 3-dimensional polytopes embedded in 7-D. The feasible activation space for a given task is <i>the</i> landscape where all neuromuscular learning, control, and performance must occur. This approach unifies current theories of neuromuscular control because the structure of feasible activation spaces can be separately approximated as either low-dimensional basis functions (synergies), high-dimensional joint probability distributions (Bayesian priors), or fitness landscapes (to optimize cost functions).