gebhart/patrepeval huggingface dataset:
The treatment of depression: A case study using theme‐analysis (2006)

Abstract Theme Analysis was applied to the transcripts of 18 counseling sessions of a middle‐age depressed male to identify the themes of depression, indicate how they are linked to each other, and to track changes on the themes across psychotherapy sessions as reflected by a change process measure. Psychotherapeutic themes were defined in terms of polarities with one pole representing the problem‐end on a continuum and the second pole representing the striving‐towards end on a continuum. The Seven‐Phase Model of the Change Process was used to assess change on the themes across the sessions. Depression was defined by DSM‐IV diagnostic criteria for a Major Depressive Episode and by the Depression Scale of the Minnesota Multiphasic Personality Inventory (MMPI). Three classes of themes were identified: descriptive, main and core. The research produced one core theme to which the other themes are linked. The results suggest that the themes change across therapy in a progressive forward manner. The theoretical implications and clinical relevance of the findings were discussed.
Torque sensors using wire explosion magnetostrictive alloy layers (1986)

The wire explosion spraying technique was applied to prepare magnetostrictive layers with strong adhesion to substrates. It has been shown that the Ni, Fe-Ni and Fe-Co-Ni layers sprayed in the form of chevron on stainless steel shafts are applicable to constitute torque sensors showing very linear output-torque characteristics with almost zero hysteresis in combination with a two-core type multivibrator bridge circuit.
Electron Temperature Dependence of Recombination of<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mrow><mml:msubsup><mml:mrow><mml:mi mathvariant="normal">O</mml:mi></mml:mrow><mml:mrow><mml:mn>2</mml:mn></mml:mrow><mml:mrow><mml:mo>+</mml:mo></mml:mrow></mml:msubsup></mml:mrow></mml:math>and<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mrow><mml:msubsup><mml:mrow><mml:mi mathvariant="normal">N</mml:mi></mml:mrow><mml:mrow><mml:mn>2</mml:mn></mml:mrow><mml:mrow><mml:mo>+</mml:mo></mml:mrow></mml:msubsup></mml:mrow></mml:math>Ions with Electrons (1969)

A microwave-afterglow/mass-spectrometer apparatus which employs microwave heating of the electrons is used to determine the recombination coefficients, $\ensuremath{\alpha}({\mathrm{O}}_{2}^{+})$ and $\ensuremath{\alpha}({\mathrm{N}}_{2}^{+})$, of mass-identified ions with electrons as a function of electron temperature. From electron-density decay data taken under good "ion-tracking" conditions it is found that $\ensuremath{\alpha}({\mathrm{O}}_{2}^{+})$ varies as ${{T}_{e}}^{\ensuremath{-}0.70}$ over the range $300\ifmmode^\circ\else\textdegree\fi{}\mathrm{K}<~{T}_{e}<~1200\ifmmode^\circ\else\textdegree\fi{}\mathrm{K}$ [starting from a value (1.95 \ifmmode\pm\else\textpm\fi{} 0.2) \ifmmode\times\else\texttimes\fi{} ${10}^{\ensuremath{-}7}$ ${\mathrm{cm}}^{3}$/sec at ${T}_{e}=300\ifmmode^\circ\else\textdegree\fi{}$K] and then varies as ${{T}_{e}}^{\ensuremath{-}0.56}$ between 1200 and 5000\ifmmode^\circ\else\textdegree\fi{}K. In the nitrogen studies the "ion tracking" of the electron decay is less perfect, but ${\mathrm{N}}_{2}^{+}$ remains the principal afterglow ion and $\ensuremath{\alpha}({\mathrm{N}}_{2}^{+})$ is found to vary as ${{T}_{e}}^{\ensuremath{-}0.39}$ over the entire range $300\ifmmode^\circ\else\textdegree\fi{}\mathrm{K}<~{T}_{e}<~5000\ifmmode^\circ\else\textdegree\fi{}\mathrm{K}$, starting from a value (${1.8}_{\ensuremath{-}0.2}^{+0.4}$) \ifmmode\times\else\texttimes\fi{} ${10}^{\ensuremath{-}7}$ ${\mathrm{cm}}^{3}$/sec at ${T}_{e}=300\ifmmode^\circ\else\textdegree\fi{}$K. These results are compared with other laboratory determinations, results of theoretical calculations, and values inferred from analyses of ionospheric measurements.
Current Issues of Targeted Therapy in Metastatic Triple-Negative Breast Cancer (2011)

Patients with triple-negative breast cancer are characterized by a poor prognosis compared with patients with other breast cancer subtypes. The angiogenesis inhibitor bevacizumab is effective in the palliative treatment of patients with triple-negative breast cancer as well as in other breast cancer subtypes. PARP inhibitors represent the first group of targeted agents to be developed under the particular aspect of treating patients with hereditary and triple-negative breast cancer. In addition, an increasing number of studies have demonstrated a significant and clinically relevant change in phenotype between primary tumor and metastasis. Consequently, it should be an essential component of the design of modern clinical trials of targeted agents in metastatic breast cancer to determine the relevant tumor phenotype and, depending on the clinical situation, confirm the presence of the therapeutic target in metastatic lesions.
Development of low-cost fly ash bricks (2008)

Fly ash is produced in vast quantities as a by-product of the burning of fossil fuels for the thermal generation of electricity. At present 10-15% of the fly ash produced in Australia is utilised in cement manufacturing and concrete industry, with the remaining majority requiring costly disposal processes. Due to growing environmental concerns and the need for cleaner production, the management of fly ash has become an important issue facing the power generation industry. For that reason, many researchers are actively working to find new and improved methods of combating the fly ash waste disposal problem, particularly by establishing its useful and economic utilisation. One such example that is gaining considerable interest in many parts of the world is the utilisation of fly ash in brick manufacturing. This paper examines the potential for using Class F fly ashes from Queensland as major constituents in the manufacture of common residential building bricks. Scaled-down pressed bricks were made by varying proportions of fly ash, sand, hydrated lime, sodium silicate and water. Both fired, oven-dried and air-cured bricks were tested for their properties including compressive strength, tensile strength, water absorption, and durability. In the paper, the test results are analysed and effects of variables discussed. Recommendations and conclusions as to whether or not the fly ash bricks can perform adequately alongside the clay bricks are included.
Recognition of Kannada Characters in Scene Images using Neural Networks (2019)

In recent years, there has been significant progress in recognition of text from scene images. However, very less work is done for Kannada language. The focus of this paper is to identify Kannada character set. Researchers have purported a number of deep learning procedures for natural scene text detection and recognition. In this work, basic transfer learning neural network classification models are trained with 1700 scene Kannada character images extracted from Chars74K standard dataset, and labelled individual folders as per character names. Stochastic gradient descent solver with different epoch, learning rate and momentum is applied. Also, the performance of Alex net model is improved by inducing a batch normalization layer in the hidden layers. The results show that for characteristic features of Kannada text, the combination of Vgg19 network model used with higher split ratio and stated training options and values gave 100% accuracy. Also, the modified Alex net model performed better with accuracy up to 96 percent and lower error rate of 0.0134.
Building an adaptable, fault tolerant, and highly manageable web server on clusters of non-dedicated workstations (2002)

Clustered server architecture is increasingly being viewed as a successful and cost-effective approach to building a high-performance Web server. Existing server-clustering schemes have typically concentrated on the following issues: scalability, high availability, and user transparency. In this paper, we argue that the design goals of the Web server cluster should include adaptability, fault tolerance, and high manageability. In the presence of the Internet's highly unpredictable workload, the server system should be self-adapting to changing circumstances. We address this problem by building a Web server on a cluster of non-dedicated workstations. Such a server can easily recruit non-dedicated nodes dynamically in response to load bursts. Based on such a scheme, we designed and implemented an innovative approach that enables an ongoing request to be smoothly migrated to another node either in response to a node failure or overload. We also designed and implemented a management system that enables the Web site manager to manage and maintain the distributed server as a single large system.
NEW TECHNOLOGY EVALUATES VULNERABILITY OF CRITICAL STRUCTURES TO EARTHQUAKES (1997)

Technology to evaluate and detect vulnerability to earthquake damage of certain critical structures is currently being developed by the U.S. Army Corps of Engineers Waterways Experiment Station (WES) in Vicksburg, Mississippi, as part of the Corps' earthquake engineering (EQEN) research program. The procedures being tested and evaluated are currently directed at dams but can be applied to other critical structures such as airport control towers. Documentation on the design of these procedures is expected to be available to the general public sometime in the fall of 1997.
The life cycle of <i>Reticulitermes</i> spp. (Isoptera: Rhinotermitidae): what do we know? (2003)

The subterranean termites in the genus Reticulitermes have a complex and plastic life cycle, which has been the subject of a number of publications over the past century. Given the inherent difficulties in studying such cryptic, eusocial organisms it is not perhaps surprising that the literature on their biology has failed to reach a consensus. An overview of the literature is given, which is followed by a discussion of the various theories on the life cycle of Reticulitermes spp. A substantial proportion of the review focuses on the French literature, which constitutes the majority of the primary sources and can be difficult to access. There are many discrepancies in the literature in terms of the number of instars, the definition of workers and the question of whether they should be termed pseudergates or, potentially, an additional terminology used to differentiate between pseudergates and the true workers seen in the higher termites (Isoptera: Termitidae). It remains very difficult to compare publications as there is little conformity; a problem that is aggravated by a general absence of drawings of the relevant instars. Further work on the biology of Reticulitermes is clearly required. There is also a need for researchers to agree on a standard terminology for this genus. A glossary is provided for the various synonyms and definitions.
Towards Autonomous Topological Place Detection Using the Extended Voronoi Graph (2006)

Autonomous place detection has long been a major hurdle to topological map-building techniques. Theoretical work on topological mapping has assumed that places can be reliably detected by a robot, resulting in deterministic actions. Whether or not deterministic place detection is always achievable is controversial; however, even topological mapping algorithms that assume non-determinism benefit from highly reliable place detection. Unfortunately, topological map-building implementations often have hand-coded place detection algorithms that are brittle and domain dependent. This paper presents an algorithm for reliable autonomous place detection that is sensor and domain independent. A preliminary implementation of this algorithm for an indoor robot has demonstrated reliable place detection in real-world environments, with no a priori environmental knowledge. The implementation uses a local, scrolling 2D occupancy grid and a real-time calculated Voronoi graph to find the skeleton of the free space in the local surround. In order to utilize the place detection algorithm in non-corridor environments, we also introduce the extended Voronoi graph (EVG), which seamlessly transitions from a skeleton of a midline in corridors to a skeleton that follows walls in rooms larger than the local scrolling map.
Commentary: Ichthyosis and Keratinization (1982)

Concepts that account for disease manifestations are necessarily seen in terms of the kind of science in vogue at the moment. At the peak of interest in the cell cycle, a decade or longer ago, patterns of mitotic replication were studied in a number of epithelial disorders. The information obtained from these studies gave a new kind of understanding to these disorders. From time to time, it is important to reexamine all the fundamentals of a disease in an attempt to improve the prevailing concepts. A reexamination of the ichthyoses in such a framework may be timely now. Some new areas of information may provide new clues to the nature of the disorders themselves as well as to other disorders in which disturbed keratinization is a major determinant of disease expression, including such disparate diseases as dry skin, keratoses, warts, and acne. The singular aspect of the diseases known as
Avances recientes en el tratamiento del retinoblastoma. (1998)

El tratamiento del retinoblastoma ha ido cambiando progresivamente a lo largo del ultimo siglo y existe una tendencia actual hacia los tratamientos mas conservadores. En primer lugar, esto se debe a la deteccion precoz de la enfermedad, cuando los tumores se encuentran tanto en un estadio inicial del desarrollo como en el avanzado, y a las modalidades de tratamiento mas focal. La enucleacion todavia se utiliza en los retinoblastomas avanzados, especialmente cuando hay evidencias de una posible invasion del nervio optico, la coroides o bien de la orbita. En los ultimos anos, los implantes de orbita integrados, como por ejemplo los implantes de hidroxiapatita, han supuesto una mejora en la rehabilitacion cosmetica de la cavidad orbitaria tras la enucleacion. La radioterapia externa sigue siendo un importante metodo para el tratamiento de los retinoblastomas avanzados, especialmente cuando hay una invasion difusa del vitreo. Las placas de radioterapia son utiles para controlar los retinoblastomas de tamano medio o pequeno, especialmente los tumores con diseminacion vitrea focal o bien aquellos que recidivan tras el fracaso de otros metodos. La crioterapia y la fotocoagulacion proporcionan controles excelentes de los tumores pequenos y los mas novedosos sistemas de tratamiento con laser han mejorado la visualizacion y han facilitado el tratamiento del retinoblastoma. La termoterapia y la quimiotermoterapia son los metodos focales mas novedosos, con los cuales se estan consiguiendo resultados prometedores para los retinoblastomas de tamano pequeno y mediano. La quimioreduccion, tecnica que utiliza la quimioterapia para reducir el volumen del tumor, lo que permite la consolidacion del tratamiento focal, ha hecho posible para muchos ninos con retinoblastomas avanzados evitar la radioterapia externa y la enucleacion. La quimioreduccion, combinada con la crioterapia, la termoterapia y las placas de radioterapia, juega un papel importante en el tratamiento de muchos ninos afectados de retinoblastoma.
Altering coenzyme specificity of Pichia stipitis xylose reductase by the semi-rational approach CASTing (2007)

A seemingly simplistic and yet very effective mutagenesis approach, CASTing, was applied successfully to alter the NAD(P)H preference for Pichia stipitis xylose reductase, an important enzyme for xylose-fermenting yeast. The observed change in the NAD(P)H preference for this enzyme seems to have resulted from the altered active site that is more unfavorable for NADPH than NADH in terms of both Km and kcat. There are potentials for application of our PsXR in constructing a more balanced XR-XDH pathway in recombinant xylose-fermenting S. cerevisiae strains.
Particle Sizing Methods for The Detection of Protein Aggregates in Biopharmaceuticals (2017)

Protein aggregation is a common biological phenomenon which is responsible for degenerative diseases and is problematic in the pharmaceutical industry. According to the rules provided by regulatory agencies, industry is supposed to assess the product quality regarding the presence of subvisible particles. Also, they should evaluate the technologies that are used to measure these particles. Therefore, US FDA and industry have been looking for methods capable of accurately characterizing the protein products. Four sizing techniques reviewed here are good candidates to be used for characterization of protein and their aggregates: dynamic light scattering, size-exclusion chromatography, electron microscopy and Taylor dispersion analysis. The first three are more established techniques while the last one is a more recent and growing technique.
Qualcomm Hexagon DSP: An architecture optimized for mobile multimedia and communications (2013)

Presents a collection of slides covering the following topics: qualcomm hexagon DSP; mobile multimedia communications; VLIW; signal processing code work-packet; control code work-packet; hexagon DSP software development; and hexagon DSP power benefits.
Interferon-α and zidovudine combination therapy for chronic hepatitis B: Results of a randomized, placebo-controlled trial (1993)

Interferon-alpha therapy leads to HBeAg seroconversion in only one third of patients with chronic hepatitis B. In an attempt to increase the seroconversion rate, we investigated the combination of interferon-alpha and zidovudine in a subset of patients with presumably low response rates for interferon-alpha monotherapy. In a double-blind, controlled trial, 24 HBeAg-positive patients were randomized to receive lymphoblastoid interferon-alpha in subcutaneous doses increasing to 5 MU daily, combined with zidovudine given orally in doses increasing from 500 to 1,000 mg/day or with placebo for 16 wk. Treatment effects were monitored by quantitative assessment of HBV DNA, HBeAg and HBV DNA polymerase. Six months after termination of therapy, 1 of 12 (8%; 95% confidence interval = 2% to 39%) patients treated with interferon-alpha plus zidovudine and 2 of 12 (17%; 95% confidence interval 2% to 48%) patients from the control group exhibited responses (HBeAg seroconversion). All patients remained HBsAg positive. The only responder of the interferon-alpha-zidovudine group relapsed after cessation of therapy, so none of the zidovudine-treated patients were HBeAg negative at the end of follow-up. No significant difference in AST level or in any of the virological markers was observed between the two groups during the course of the study. Adverse effects (anemia, leukopenia) necessitated reduction in the dose of zidovudine in 50% and of interferon-alpha in 42% of the patients treated with interferon-alpha plus zidovudine; in the control group these rates were 0% for placebo and 8% for interferon-alpha. In conclusion, the antiviral effect of interferon-alpha in chronic hepatitis B was not enhanced by additional zidovudine treatment. The combination therapy induced considerable side effects leading to dose reduction for both zidovudine and interferon-alpha. For combination therapy with interferon-alpha, oral nucleoside analogs with more potent antiviral effects and less toxicity than zidovudine should be developed.
Fabrication of AlGaN/GaN Ω-shaped nanowire fin-shaped FETs by a top-down approach (2015)

International audience
Drug delivery systems (2000)

Drug delivery systems have an important role to play in the administration of drugs, vaccines, and diagnostic agents. Systems based on biodegradable polymers can be especially advantageous for use as implants that provide a slow, steady release of a pharmacological agent. Materials include poly--hydroxy acids, polyanhydrides, and polyphosphazenes. The products of biotechnology in the form of peptides and proteins are challenging compounds that are difficult to deliver. Novel methods of delivery include polymeric microspheres and microcapsules. Polymers can be used to deliver antigens in order to obtain improved responses after injection. Nanoparticles based on polymeric materials can be employed to deliver drugs to specific target sites, especially via the bloodstream or lymphatic system. Natural polymers also have an important role in drug delivery, for example chitosan is of special interest for its ability to interact with mucosal surfaces and to provide a bioadhesive effect that will retain drugs at target sites.
Job-Related Training in Europe: Do Institutions Matter? (2007)

Abstract This chapter compares the incidence, the distribution, as well as the impact of continuing vocational training and employer-sponsored vocational training across a number of European countries. In particular, it assesses whether continuing training alleviates or exacerbates existing inequalities of work-life chances. The findings are summarized in the chapter as follows: there was no evidence of systematic differences in the distribution of training opportunities and the financial returns to training relating to differences in production systems and employment regimes. However, there was strong evidence that the volume of continuing training is by far the highest in the inclusive employment regimes of Denmark and Finland.
Cancellation of multiple harmonic noise series in geophysical records (2003)

Abstract We describe a procedure for the simultaneous estimation of multiple stationary sinusoidal contaminants in a time series and demonstrate its application to the cancellation of powerline noise in seismic and seismoelectric records. An estimate of the noise in each record is obtained by seeking a linear combination of sinusoids that are harmonics of one or more fundamental frequencies; this combination must fit the data in a least-squares sense. The algorithm accommodates estimation windows of arbitrary length, including windows shorter than one fundamental period, without cross-contamination between harmonic estimates. Provision is made for refining the fundamental frequencies, for which small errors (e.g., 0.01 Hz in 60 Hz) can result in significant residual noise near the ends of the record (beating). Our strategy is novel in that it uses all specified harmonics and iteratively searches frequency space for a best fit using numerical derivatives. This determination is very robust for at least two fundamentals (the limit of our investigation) and often converges rapidly to three or four decimal places. Cancellation of harmonic noise has been essential in our research to uncover seismoelectric signals that are often completely masked by powerline noise. We expect this procedure will be useful in other geophysical methods—especially exploration seismology, for which powerline contamination is a recognized problem.
Site Security Handbook (1997)

This handbook is a guide to developing computer security policies and procedures for sites that have systems on the Internet. The purpose of this handbook is to provide practical guidance to administrators trying to secure their information and services. The subjects covered include policy content and formation, a broad range of technical system and network security topics, and security incident response.
WHY MOZART IN THE <i>NACHTWACHEN</i>? (1987)

WHY MOZART IN THE NACHTWACHEN? Get access PAUL DAVIES PAUL DAVIES Kingston, Ontario Search for other works by this author on: Oxford Academic Google Scholar Forum for Modern Language Studies, Volume XXIII, Issue 3, July 1987, Pages 265–273, https://doi.org/10.1093/fmls/XXIII.3.265 Published: 01 July 1987