gebhart/patrepeval huggingface dataset:
Mild Cognitive Impairment — No Benefit from Vitamin E, Little from Donepezil (2005)

In this issue of the Journal, Petersen et al. present the long-awaited results of a randomized, placebo-controlled trial of donepezil, a standard therapy for Alzheimer's disease, and the widely used antioxidant vitamin E as an early intervention for mild cognitive impairment — essentially the prodromal phase of Alzheimer's disease.1 The implications of this study for primary care medicine and for public health are enormous. The clear-cut negative findings for vitamin E, which is widely used despite the dearth of evidence of its efficacy, are especially noteworthy. The findings for donepezil, on the other hand, are much less clear.Mild cognitive . . .
Application of α-chloroglycine residues for the modification of oligopeptides (1994)

Abstract
Improvements in Isotopic Carbon Assay and Chemical Analysis of Organic Compounds by Dry Combustion (1955)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTImprovements in Isotopic Carbon Assay and Chemical Analysis of Organic Compounds by Dry CombustionD. R. Christman, N. E. Day, P. R. Hansell, and R. C. AndersonCite this: Anal. Chem. 1955, 27, 12, 1935–1939Publication Date (Print):December 3, 1955Publication History Published online1 May 2002Published inissue 3 December 1955https://pubs.acs.org/doi/10.1021/ac60108a025https://doi.org/10.1021/ac60108a025research-articleACS PublicationsRequest reuse permissionsArticle Views20Altmetric-Citations25LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Intraneuronal Substance P Contributes to the Severity of Experimental Arthritis (1984)

There is evidence that substance P is a peptide neurotransmitter of some unmyelinated primary afferent nociceptors and that its release from the peripheral terminals of primary afferent fibers mediates neurogenic inflammation. The investigators examined whether substance P also contributes to the severity of adjuvant-induced arthritis, an inflammatory disease in rats. They found that, in the rat, joints that developed more severe arthritis (ankles) were more densely innervated by substance P-containing primary afferent neurons than were joints that developed less severe arthritis (knees). Infusion of substance P into the knee increased the severity of arthritis; injection of a substance P receptor antagonist did not. These results suggest a significant physiological difference between joints that develop mild and severe arthritis and indicate that release of intraneuronal substance P in joints contributes to the severity of the arthritis.
Démocratie électronique : quelques jalons dans la généalogie d'une question (2003)

L'article se propose d'examiner la pertinence de la notion de democratie electronique. Celle-ci repose sur une assimilation entre democratie et communication qui souleve beaucoup de difficultes en raison de la polysemie des deux notions et du risque de verser dans le determinisme technique. C'est pourquoi, la question de la democratie electronique est ensuite replacee dans une perspective historique : celle de la delegation a la technique des questions politiques. Depuis la Seconde guerre mondiale, trois periodes sont distinguees en croisant trois criteres : les problemes politiques envisages, la technique privilegiee et les orientations ideologiques affichees.
PIC (products of incomplete combustion) formation under pyrolytic and starved-air conditions. Report for October 1984-October 1985 (1986)

A comprehensive program of laboratory studies based on the non-flame mode of thermal decomposition produced much data on PIC (Products of Incomplete Combustion) formation, primarily under pyrolytic and starved-air conditions. Most significantly, laboratory results from non-flame studies were compared to those from various field tests to evaluate incinerability relationships. Measurement of gas-phase thermal stability in an atmosphere of low oxygen concentration yielded results of incinerability ranking that were far more consistent with the findings from field tests than any one of several common methods applied in the past such as those that employed heat of combustion, autoignition temperature, etc. The results of four experimental studies were presented as significant contributions to developing/expanding the data base on POHC (Principal Organic Hazardous Constituent) stability and PIC formation for pure compounds and mixtures.
Spin-Isomer Conversion of Water at Room Temperature and Quantum-Rotor-Induced Nuclear Polarization in the Water-Endofullerene <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mrow><mml:msub><mml:mrow><mml:mi mathvariant="normal">H</mml:mi></mml:mrow><mml:mrow><mml:mn>2</mml:mn></mml:mrow></mml:msub><mml:mi mathvariant="normal">O</mml:mi><mml:mo>@</mml:mo><mml:msub><mml:mrow><mml:mi mathvariant="normal">C</mml:mi></mml:mrow><mml:mrow><mml:mn>60</mml:mn></mml:mrow></mml:msub></mml:mrow></mml:math> (2018)

Water exists in two forms, para and ortho, that have nuclear spin states with different symmetries. Here we report the conversion of fullerene-encapsulated para water to ortho water. The enrichment of para water at low temperatures is monitored via changes in the electrical polarizability of the material. Upon rapid dissolution of the material in toluene the excess para water converts to ortho water. In H_{2}^{16}O@C_{60} the conversion leads to a slow increase in the NMR signal. In H_{2}^{17}O@C_{60} the conversion gives rise to weak signal enhancements attributed to quantum-rotor-induced nuclear spin polarization. The time constants for the para-to-ortho conversion of fullerene-encapsulated water in ambient temperature solution are estimated as 30±4 s for the ^{16}O isotopolog of water, and 16±3 s for the ^{17}O isotopolog.
Interpreting CD56+ and CD163+ Infiltrates in Early versus Late Renal Transplant Biopsies (2015)

Intragraft CD56+ cell infiltrates were significantly associated with AMR and subsequent poor clinical outcomes.
Army Hyperspectral R&D Consortium The Way Forward (2002)

Abstract : In early 2001 four Army laboratories signed a memorandum of understanding that signifies the Army's interest in focusing research interests on practical tactical applications of hyperspectral technology. The result of the focusing of these research interests will be actual applications of hyperspectral technology in the fielded Army. The AHR&DC has been meeting informally for about 3 years and exchanging information and ideas. The AHR&DC has two Science and Technology Objectives (STOs), IV. SN .2000.04 Spectral/Spatial Data Exploitation for Terrain Categorization and Target Identification and III.Q.05 Overhead Sensor Technology for Battlefield Characterization, which it manages among the four laboratories. Recently, IV.SN.2000.04 was captured under the Defense Technology Objective (DTO), Hyperspectral Technology. Each laboratory has research experience and practical experience in the area of hyperspectral, and through the STOs and DTO are moving the basic and applied research experience into practical applications for the Army. The AHR&DC has set goals of transitioning more hyperspectral technology into Army systems that may be used in Future Combat Systems and/or Objective Force Warrior. This paper details some of the collaborations and applications that the Army labs are considering for tactical applications of hyperspectral technology. The goal of the Army partners of the Army Hyperspectral R&D Consortium is to explore, develop, and transition tactical hyperspectral technology to Army customers. Recently, the Army laboratories realized that the Army research and development program in hyperspectral needed coordination and focus to achieve their technology goals. A Memorandum of Agreement was drawn up and signed by the Army partners. The four Army partners were already collaborating on two STOs. Each of the partners also have in-house R&D program with different scope and focus.
Cumulative Update of All-Terminal Reliability for Faster Feasibility Decision (2010)

Designing a reliable network becomes a time-consuming task if it involves All-Terminal Reliability (ATR) calculation, which belongs to the class of NP-hard problems. To make this task easier to address, we propose a new algorithm to decide the ATR feasibility of a given network <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">G</i> without performing exhaustive calculation. The proposed algorithm cumulatively updates the lower and upper bounds of the ATR using the set of subnetworks decomposed or branched from <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">G</i> . Once the lower or upper bound reaches the predetermined ATR requirement, the feasibility of <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">G</i> is determined. The proposed algorithm is characterized by four existing ATR calculation methods, which decompose or branch <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">G</i> into multiple subnetworks. The four implementations of the proposed algorithm will be tested via computer experiments. The results show that the proposed algorithm can make feasibility decision dramatically faster. The arrangement of subnetworks that can improve the performance of the proposed algorithm is also discussed.
Patient Perspectives on Innovative Telemonitoring Enhanced Care Program for Chronic Heart Failure (ITEC-CHF): Usability Study (Preprint) (2020)

<sec> <title>BACKGROUND</title> Telemonitoring enables care providers to remotely support outpatients in self-managing chronic heart failure (CHF), but little is known about the usability and patients’ willingness to engage with this technology. </sec> <sec> <title>OBJECTIVE</title> This study aims to evaluate feedback from patients with CHF following participation in the Innovative Telemonitoring Enhanced Care program for CHF (ITEC-CHF) study. </sec> <sec> <title>METHODS</title> The telemonitoring intervention consisted of three components: remote weight monitoring, structured telephone support, and nurse-led collaborative care. Participants were provided with electronic weighing scales (W550; ForaCare), and a computer tablet (Galaxy Tab A; Samsung). They were asked to weigh themselves on the provided scales daily. Telemonitoring was integrated with a personal assistance call service and a nurse care service according to their workflows in usual care. Feedback on the usability of ITEC-CHF was collected via survey from study participants following 6 months of receiving telemonitoring care for their body weight. Survey responses were provided on a 5-point Likert scale and through open-ended questions to determine participants’ perceived benefits and barriers to using ITEC-CHF. </sec> <sec> <title>RESULTS</title> A total of 67 participants (49/67, 73% male), with a mean age of 69.8 (SD 12.4) years completed the survey. The majority of participants agreed or strongly agreed that the ITEC-CHF program was easy to use (61/67, 91%), easy to navigate (51/65, 78%), useful (59/65, 91%), and made them feel more confident in managing their weight (57/67, 85%). Themes related to participants’ perceptions of telemonitoring included increased support for early intervention of clinical deterioration, improved compliance to daily weighing, a sense of reassurance, and improved self-care and accountability, among others. </sec> <sec> <title>CONCLUSIONS</title> ITEC-CHF was rated highly on usability and was well accepted by users as part of their routine self-management activities. Participants were willing to use telemonitoring because they perceived a broad spectrum of benefits for CHF management. </sec> <sec> <title>CLINICALTRIAL</title> Australian New Zealand Clinical Trial Registry ID ACTRN 12614000916640; https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=366691. </sec>
BEsTRF: a tool for optimal resolution of terminal-restriction fragment length polymorphism analysis based on user-defined primer–enzyme–sequence databases (2009)

BEsTRF is freely available at http://lie.fe.uni-lj.si/bestrf and can be downloaded from the same site. The online protocol, numerous primer and enzyme dictionaries, sequence collections and results generated during this work for various genes are available at our website http://lie.fe.uni-lj.si/bestrf.
All-optical switching devices based on large nonlinear phase shifts from second harmonic generation (1993)

We show that the large nonlinear phase shifts obtained from phase-mismatched second harmonic generation can be used to implement all-optical switching devices such as a nonlinear Mach–Zehnder interferometer and a nonlinear directional coupler.
THE SYNTHESIS OF ALANYL-α-AMINOPROPIONITRILES-(<scp>Dl-dl</scp>, <scp>L-DL</scp>, and <scp>L-L</scp>) BY DEHYDRATING THE CORRESPONDING <i>N</i>-<i>o</i>-NITROPHENYLSULFENYLALANYLALANINE AMIDES (1975)

Abstract N-o-Nitrophenylsulfenylalanylalanine amides(Dl-dl, L-DL, and L-L) were dehydrated In POCl3-pyridine without affecting their N-protecting groups. The N-protected dipeptide nitriles obtained were treated with anhydrous HCl in ethyl acetate to give the hydrochlorides of the corresponding dipeptide nitriles. The results of ion exchange chromatography of these products Indicated that the optical purity of the α-aminopropionitrile group was well retained.
A long pulse discharge excited ArF laser (1999)

An X-ray preionised, discharge excited ArF excimer laser, /spl lambda/=193 nm, has been studied in the long pulse regime. The laser performance is found to be primarily dependent on the discharge stability, and therefore, on the gas composition, preionization timing and the pumping power. Using X-ray preionization and prepulse-mainpulse excitation, laser pulselengths of up to 120-ns full-width at half-maximum at 4 mJ/l are obtained by decreasing the partial pressures of the active ingredients, F/sub 2/ and Ar, and using Ne as a buffer gas. This is almost six times as long as usual for discharge excited ArF lasers.
Pyrolysis Characteristics and Char Reactivity of <i>Oedogonium</i> sp. and Loy Yang Coal (2015)

The proposition of combining the application of algae in wastewater treatment, CO2 fixation, and energy production maximizes the opportunity of algal bioremediation. In this paper, the freshwater macroalga Oedogonium, a key target species for the bioremediation of waste waters, was investigated for its utilization in energy production via gasification or co-gasification with coal. The pyrolysis characteristics of Oedogonium and the effects of pyrolysis conditions on char reactivity were investigated in this paper, and an Australian lignite was also studied for comparison purposes. The pyrolysis process of Oedogonium and coal can be divided into three stages: moisture evaporation, volatile release, and decomposition of the remaining carbonaceous compounds. However, the devolatilization of Loy Yang coal was slower and occurred over a wider temperature range compared to Oedogonium. As the heating rate increased, the pyrolysis curves for both Oedogonium and Loy Yang coal shifted to higher temperatures. To investigate the effects of pyrolysis conditions on char reactivity, a tube reactor was employed to generate char samples under a range of pyrolysis conditions. The produced char samples were characterized using a CHN analyzer and scanning electron microscopy technique. It was found that char samples almost maintain their original shape following pyrolysis at a low heating rate. However, evidence of char swelling was observed in the structure of chars prepared at a high heating rate. Pyrolysis conditions also had a significant influence on the reactivity of the derived chars. Char reactivity for both fuels was enhanced at a higher heating rate and lower pyrolysis temperature. Oedogonium char reactivity was around 2–5 times that of Loy Yang char prepared under the same pyrolysis conditions. However, the differences in reactivity became less significant as the pyrolysis temperature increased. Oedogonium has a higher devolatilization rate and higher char reactivity than Loy Yang lignite. It implies that it is easier to be gasified, and the co-gasification with lignite is advantageous.
Computed tomography of x-ray index of refraction using the diffraction enhanced imaging method (2000)

Diffraction enhanced imaging (DEI) is a new, synchrotron-based, x-ray radiography method that uses monochromatic, fan-shaped beams, with an analyser crystal positioned between the subject and the detector. The analyser allows the detection of only those x-rays transmitted by the subject that fall into the acceptance angle (central part of the rocking curve) of the monochromator/analyser system. As shown by Chapman et al, in addition to the x-ray attenuation, the method provides information on the out-of-plane angular deviation of x-rays. New images result in which the image contrast depends on the x-ray index of refraction and on the yield of small-angle scattering, respectively. We implemented DEI in the tomography mode at the National Synchrotron Light Source using 22 keV x-rays, and imaged a cylindrical acrylic phantom that included oil-filled, slanted channels. The resulting 'refraction CT image' shows the pure image of the out-of-plane gradient of the x-ray index of refraction. No image artefacts were present, indicating that the CT projection data were a consistent set. The 'refraction CT image' signal is linear with the gradient of the refractive index, and its value is equal to that expected. The method, at the energy used or higher, has the potential for use in clinical radiography and in industry.
Transport of Lead‐203 at the Blood‐Brain Barrier During Short Cerebrovascular Perfusion with Saline in the Rat (1990)

Lead transport at the blood-brain barrier has been studied by short (less than 1.5 min) vascular perfusion of one cerebral hemisphere of the rat with a buffered physiological salt solution at pH 7.4 without calcium, magnesium, or bicarbonate and containing 203 Pb-labelled lead chloride. In the absence of complexing agents, 203Pb uptake was rapid, giving a space of 9.7 ml/100 g of wet frontal cortex at 1 min. Lead-203 influx was linear with lead concentration up to 4 microM. Five percent albumin, 200 microM cysteine, or 1 mM EDTA almost abolished 203Pb uptake. Lead-203 entry into brain was uninfluenced by varying the calcium concentration or by magnesium or the calcium blocker methoxyverapamil. Similarly, 1 mM bicarbonate or 50 microM 4,4'-diisothiocyanostilbene-2,2'-disulphonic acid was without effect. Increasing the potassium concentration reduced 203Pb uptake. Vanadate at 2 mM, 2 microM carbonyl cyanide 4-(trifluoromethoxy)phenylhydrazone (a metabolic uncoupler), or 2 microM stannic chloride all markedly enhanced lead entry into brain, as did a more alkaline pH (7.80). In conclusion, there is a mechanism allowing rapid passive transport of 203Pb at the brain endothelium, perhaps as PbOH+. Lead uptake into brain via this system is probably made less important by active transport of lead back into the capillary lumen by the calcium-ATP-dependent pump.
DURABILITY AND LONG-TERM BEHAVIOR OF CARBON AND ARAMID FRP TENDONS (1998)

Fiber reinforced plastics (FRPs) provide a potential solution to the corrosion problem of steel tendons. This paper presents durability test results of two carbon tendons and one aramid FRP tendon exposed to simulated field conditions. Carbon and aramid tendons exhibited excellent durability under exposure to freeze-thaw cycles, alkaline, acidic and deicing salt solutions. In addition, the fatigue and relaxation behaviors were also examined. Relaxation losses increased with the increase in initial stress ratio, and temperature, and they were higher in solutions than in air. In general, carbon tendons exhibited excellent fatigue characteristics for stresses up to 70% of ultimate strength and stress range up to 10% of ultimate.
Abstract B167: Antigen-presenting cells as coordinators of T-cell responses to gut microbiota (2019)

Abstract The immune system in the gut mucosa must balance tolerance to harmless diet and microbial antigens with the ability to mount effective inflammatory responses to diverse invasive pathogens. These requirements are reflected in the functions of distinct subsets of T-cells whose differentiation is guided by diverse cytokines secreted by antigen-presenting cells (APCs). In recent years, different APCs subsets have been proposed to guide CD4+ T-cell polarization and to induce primary T-cell responses in lymph nodes versus secondary responses in tissues. However, the exact roles of APC subsets in mediating T-cell responses to gut microbiota are still under debate and have not been thoroughly addressed. We previously showed that the commensal microbe segmented filamentous bacteria (SFB) induces antigen-specific Th17 cells, while Helicobacter hepaticus (Hh) induces an antigen-specific Treg response. Using those microbial models, I am now studying the contribution of APC subsets to specific T-cell response. I utilize several different approaches to track APC subsets that presents the relevant microbial peptides in the mesenteric lymph node and to characterize their contribution to T-cell priming and polarization. A better understanding of which APCs participate in the differentiation of each category of T-cell will enable in the future to develop better tools to educate T-cells to fight cancer. Citation Format: Ranit Kedmi, Kai Mesa, Dan Littman. Antigen-presenting cells as coordinators of T-cell responses to gut microbiota [abstract]. In: Proceedings of the Fourth CRI-CIMT-EATI-AACR International Cancer Immunotherapy Conference: Translating Science into Survival; Sept 30-Oct 3, 2018; New York, NY. Philadelphia (PA): AACR; Cancer Immunol Res 2019;7(2 Suppl):Abstract nr B167.
Code generation schema for modulo scheduled loops (1992)

article Free Access Share on Code generation schema for modulo scheduled loops Authors: B. Ramakrishna Rau View Profile , Michael S. Schlansker View Profile , P. P. Tirumalai View Profile Authors Info & Claims ACM SIGMICRO NewsletterVolume 23Issue 1-2Dec. 1992 pp 158–169https://doi.org/10.1145/144965.145795Published:10 December 1992Publication History 50citation660DownloadsMetricsTotal Citations50Total Downloads660Last 12 Months64Last 6 weeks14 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my Alerts New Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteeReaderPDF