gebhart/patrepeval huggingface dataset:
<title>Integrated, dynamic machine vision system with virtual high resolution</title> (1993)

A novel active vision system for CIM production and inspection applications has been developed in the framework of ESPRIT II project No. 5194 (CIVIS). The system consists of a unique, integrated combination of novel components: camera head, data acquisition electronics, a custom digital image processor, control hardware and a commercial framestore, all under the direction of control and processing software on a PC-486 platform. The camera head incorporates a fast zoom lens in combination with a pan/tilt mirror system, allowing region-of-interest acquisition. The special 256 X 256 MOS image sensor offers programmable resolution and random pixel access. The unique combination of optics, optomechanics and versatile image sensor has a high `virtual resolution,' corresponding to more than 1k X 1k pixels but without the overhead of a high pixel transfer rate. The fast computation of the algorithm employed for the fractal inspection of surfaces is realized with an unusual combination of an electrically switchable hologram (for performing all linear operations at the speed of light in the optical domain), a module-based digital processor and the host computer. In this way, active vision for the inspection of concrete tile surfaces has been implemented by acquiring only relevant image data and elegantly processing them in the most appropriate domain.
Polymorphisms in the Reduced Folate Carrier, Thymidylate Synthase, or Methionine Synthase and Risk of Colon Cancer (2005)

Folate metabolism supports the synthesis of nucleotides as well as the transfer of methyl groups. Polymorphisms in folate-metabolizing enzymes have been shown to affect risk of colorectal neoplasia and other malignancies. Using data from a population-based incident case-control study (1,600 cases and 1,962 controls), we investigated associations between genetic variants in the reduced folate carrier (RFC), thymidylate synthase (TS), methionine synthase (MTR), and 5,10-methylenetetrahydrofolate reductase (MTHFR) and colon cancer risk. The TS enhancer region (TSER) variant was associated with a reduced risk among men [2rpt/2rpt versus 3rpt/3rpt wild-type; odds ratio (OR), 0.7; 95% confidence interval, 0.6-0.98] but not women. When combined genotypes for both TS polymorphisms (TSER and 3'-untranslated region 1494delTTAAAG) were evaluated, ORs for variant genotypes were generally below 1.0, with statistically significantly reduced risks among women. Neither MTR D919G nor RFC 80G>A polymorphisms were associated with altered colon cancer risk. Because folate metabolism is characterized by interrelated reactions, we evaluated gene-gene interactions. Genotypes resulting in reduced MTHFR activity in conjunction with low TS expression were associated with a reduced risk of colon cancer. When dietary intakes were taken into account, individuals with at least one variant TSER allele (3rpt/2rpt or 2rpt/2rpt) were at reduced risk in the presence of a low folate intake. This study supports findings from adenoma studies indicating that purine synthesis may be a relevant biological mechanism linking folate metabolism to colon cancer risk. A pathway-based approach to data analysis is needed to help discern the independent and combined effects of dietary intakes and genetic variability in folate metabolism.
Targeting of tumor angiogenesis using engineered Trojan Horse mesenchymal stem cells (2009)

Conrad, Claudius MD, PhD; Hüsemann, Yves PhD; Niess, Hanno MD; von Lüttichau, Irene MD, PhD; Huss, Ralf MD, PhD; Bauer, Christian MD, PhD; Jauch, Karl-Walter MD, PhD; Klein, Christoph MD, PhD; Bruns, Christiane MD, PhD; Nelson, Peter MD, PhD Author Information
Anodic performance of black phosphorus in magnesium-ion batteries: the significance of Mg–P bond-synergy (2016)

By means of first-principles analysis, we have shown that black phosphorus shows promise as a low potential and high capacity anode in Mg-ion batteries. The fact that deserves the most attention is synergistic interaction between Mg-ions and the covalent P-host that reduces the Mg-diffusion barrier and optimizes the anodic voltage, thereby can overcome the bottleneck in Mg-battery machinery.
Zyzzyva (2008)

research-article Share on Zyzzyva: speculative Byzantine fault tolerance Authors: Ramakrishna Kotla Microsoft Research Silicon Valley, Mountain View, CA Microsoft Research Silicon Valley, Mountain View, CAView Profile , Allen Clement University of Texas, Austin University of Texas, AustinView Profile , Edmund Wong University of Texas, Austin University of Texas, AustinView Profile , Lorenzo Alvisi University of Texas, Austin University of Texas, AustinView Profile , Mike Dahlin University of Texas, Austin University of Texas, AustinView Profile Authors Info & Claims Communications of the ACMVolume 51Issue 11November 2008pp 86–95https://doi.org/10.1145/1400214.1400236Published:01 November 2008Publication History 19citation4,828DownloadsMetricsTotal Citations19Total Downloads4,828Last 12 Months2,124Last 6 weeks4 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteGet Access
High porosity PTFE improves endothelialization of arterial grafts without increasing early thrombogenicity. (1993)

Given that HP PTFE is no more thrombogenic than STD PTFE, and that it provides superior endothelialization, HP grafts should continue to be developed and studied for potential clinical use.
ChemInform Abstract: Methanodibenzosuberylpiperazines as Potent Multidrug Resistance Reversal Agents. (1996)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Successful High-Pressure/High-Temperature Acidizing With In-Situ Crosslinked Acid Diversion (2000)

Abstract This paper describes a very successful acid stimulation treatment performed in AGIP’s Trecate-Villafortuna Field. The matrix acidizing treatment used in-situ crosslinked acid (ICA) as the diverting agent. The treatment is unique because it represents the highest temperature application ever attempted for such a system and falls under the definition of high-pressure high-temperature (HPHT). The design process included temperature simulations, detailed laboratory testing, and a review of acid formulations that were used successfully in the Trecate-Villafortuna Field and elsewhere. Temperature simulations indicated that cooldown from the bottomhole temperature (BHT) of 180°C to at least 150°C could be achieved despite the high treating pressures that limited injection rates. Even after cooldown, serious concerns about corrosion and the effectiveness of the ICA system still existed. Laboratory support included fluid optimization for high-temperature application of the ICA. The flow tests enabled the selection of the most appropriate base acid systems and demonstrated that the ICA system would indeed function at the predicted high temperatures. Success of the treatment must also be attributed to the operational planning and close attention to experience gained from previous stimulation treatments. The execution of the treatment used all of the components considered to be state-ofthe-art in matrix acidizing treatment execution and evaluation: prestimulation injection tests, spotting of acid with coiled tubing (CT) to help reduce injection pressures and improve zonal coverage, the use of the Maximum Pressure Maximum Rate Diversion Technique (MAPDIR), and real-time treatment pressure monitoring. The paper will present job procedures and a detailed treatment pressure analysis. It will also give details on the changes in injectivity and the Productivity Index (PI) before and after stimulation.
S -parameter formulation of quality factor for a spiral inductor in generalized two-port configuration (2003)

This paper formulates various quality (Q) factors associated with the applications of on-chip spiral inductors to radio-frequency integrated circuits using S-parameters. The formulations start with the Q factor of a spiral inductor in a generalized two-port configuration based on a new complex-power approach and then extend to the Q factors of a tank and matching circuits that use the spiral inductors. In the demonstration, the two-port S-parameters for a series of CMOS spiral inductors have been measured to further generate such various Q factors for a many-sided evaluation of the inductor performance.
POD Analysis of 3-D Flow Visualization Images of a Circular Jet with Reynolds Number 9500 (2009)

A three-dimensional (3-D) modal analysis of an excited circular jet with Reynolds number of 9500 is conducted using proper orthogonal decomposition (POD) and a highspeed 3-D flow visualization system. Large sets of 3-D data are acquired in the near field before the end of the potential core and the transition region of the jet. POD is used to objectively characterize and classify the 3-D images and elucidate the fundamental structure of the flow. As expected, the near field of the jet is dominated by the formation and growth of ring vortices, which is also reflected in the shape of the POD modes. The onset of azimuthal instabilities is also clear in the instantaneous 3-D images, which show long streamwise fingers, or side jets, of fluid surrounding the vortex rings. The results presented here show the strength of 3-D modal analysis for understanding the most dominant structures and instabilities in the jet.
069 Scar Reduction by Adhesive Patches: Efficacy and Potential Mode of Action (2004)

There is a wide spectrum of treatment modalities to manage hypertrophic scars, techniques like surgical excision, intralesional application of corticosteroids, pressure therapy or laser therapy are extensively used. From a cosmetic and physiological point of view scars are predominantly a concern of the patients, the cosmetic relevance for doctors is often of less importance. Therefore a treatment that can be performed by the patient her‐/himself might be advantageous if it is efficacious and safe. Since the early 1980s so‐called “silicone gel sheeting” has been a widely used safe clinical management option for hypertrophic scars and keloids. The principle of the latter treatment has now been adapted and optimised towards a specific easily applicable adhesive polyurethane patch. This breathable, hypoallergenic patch is very well tolerated and avoids – in contrast to silicone sheets – moisture accumulation on the skin. Several clinical studies on both mature scars and on scar formation after surgical incisions show a reduction in visibility, redness, and roughness of the scars. The recommended eight weeks treatment might even be interrupted daily for twelve hours; the scar reducing effect is achieved as well. Extensive investigations on the polyurethane patch in vivo and in vitro propose an improved remodelling process of the scar tissue due to thermal and pressure effects of the patch but not by stratum corneum hydration. In vivo a better microcirculation can be observed in the scar tissue after treatment and in vitro an activation of enzymes involved in the remodelling process can be measured. In summary, physical effects are likely to be responsible for the successful results in clinical studies and individual applications of the new polyurethane patch for the reduction of hypertrophic scars.
Characterization of the mesostructure of HDPE under “<i>in situ</i>” uniaxial tensile test by incoherent polarized steady‐light transport (2011)

Abstract This study presents quantitative results related to in situ investigation of the microstructural evolutions of high‐density polyethylene with deformation. These results were obtained thanks to a novel technique (IPSLT) based on the polarized light scattering transport phenomenon. The heterogeneities produced during whitening of the polymer bulk are characterized at the mesoscale level (from hundred of nanometers to a few micrometers). The technique is described as well as the identified parameters it provides, namely: the average size of the scatterers, the anisotropy developed in the medium, and the light transport length, representative of both the volume fraction and size of the heterogeneities. Results obtained during video‐controlled tensile experiments confirm those obtained previously with X‐ray microtomography. They put forward the role of morphological transformations of the amorphous/crystalline phases (especially regarding the creation of fibrillar assemblies) rather than the cavitation phenomenon. © 2011 Wiley Periodicals, Inc. J Polym Sci Part B: Polym Phys, 2012
A Convenient Synthetic Method for 4-Nitro-1,3,4,5-tetrahydrobenz[cd]indoles and Its Application for an Alternative Synthesis of (±)-6,7-Secoagroclavine (1987)

Various 4-substituted indoles are prepared and a simple synthetic method for 4-nitro-1,3,4,5-tetrahydrobenz[cdl- indole derivatives is elaborated using intramolecular Michael addition reaction as a key step.Syntheses of new tetracyclic
Dielectric Functions and Critical Points of GaAsSb Alloys (2019)

We report the pseudodielectric functions and the critical points of GaAsxSb1−x ternary alloy films. Data were obtained by performing spectroscopic ellipsometry on 1-μm-thick films grown on (001) GaAs by using molecular beam epitaxy. Artifacts from surface contaminants, including oxide overlayers, were minimized by using in-situ chemical cleaning, leading to accurate representations of the bulk dielectric responses of these materials. We determined the energies of the E1, E1+Δ1, E′0, E′0+Δ′0, E2, E′2, and E′1 critical points from numerically calculated second energy derivatives, as well as their compositional dependences by using lineshape fitting.
Allele-specific measurement of low-density lipoprotein receptor transcript levels (1996)

We have developed an assay for allele-specific determination of low-density lipoprotein receptor (LDLR) mRNAs. Transcript levels are measured by reverse transcription (RT), PCR, and electrophoresis on an automatic DNA sequencer using fluorescence-labeled primers and direct quantitation of the allele-specific RT-PCR products. The discrimination between the allelic products is based on the use of DNA polymorphisms located in the coding regions of the gene as markers for the individual alleles. Using this method on LDLR mRNA from heterozygous patients with familial hypercholesterolemia (FH) due to a defective LDLR protein, it is possible to relate the expression of the mutant allele directly to the expressed amounts of the normal allele, thus overcoming the problems of using artificial internal standards in the PCR. To validate the method we have measured (1) the range of normal LDLR allele transcript levels, and (2) the transcript levels in patients heterozygous for different types of mutant LDLR alleles associated with FH. The method is general in principle and can be applied in the allele-specific analysis of transcripts from all genes harbouring DNA polymorphisms in their coding regions.
Accumulator-based compaction for built-in self test of data-path architectures (2003)

Accumulators composed of adders and registers are commonly used building blocks in general-purpose computing structures based on data-path architecture. The authors introduce a new accumulator-based compaction scheme for parallel compaction of test responses. The proposed scheme is compatible with the width of the data path, the hardware overhead is minimal, it does not introduce any performance degradation, and the compaction quality is the same as that offered by linear feedback shift registers.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Feasibility of Affibody Molecule-Based PNA-Mediated Radionuclide Pretargeting of Malignant Tumors (2015)

Affibody molecules are small (7 kDa), non-immunoglobulin scaffold proteins with a potential as targeting agents for radionuclide imaging of cancer. However, high renal re-absorption of Affibody molecules prevents their use for radionuclide therapy with residualizing radiometals. We hypothesized that the use of Affibody-based peptide nucleic acid (PNA)-mediated pretargeting would enable higher accumulation of radiometals in tumors than in kidneys. To test this hypothesis, we designed an Affibody-PNA chimera ZHER2:342-SR-HP1 containing a 15-mer HP1 PNA recognition tag and a complementary HP2 hybridization probe permitting labeling with both (125)I and (111)In. (111)In-ZHER2:342-SR-HP1 bound specifically to HER2-expressing BT474 and SKOV-3 cancer cells in vitro, with a KD of 6±2 pM for binding to SKOV-3 cells. Specific high affinity binding of the radiolabeled complementary PNA probe (111)In-/(125)I-HP2 to ZHER2:342-SR-HP1 pre-treated cells was demonstrated. (111)In-ZHER2:342-SR-HP1 demonstrated specific accumulation in SKOV-3 xenografts in BALB/C nu/nu mice and rapid clearance from blood. Pre-saturation of SKOV-3 with non-labeled anti-HER2 Affibody or the use of HER2-negative Ramos xenografts resulted in significantly lower tumor uptake of (111)In-ZHER2:342-SR-HP1. The complementary PNA probe (111)In/(125)I-HP2 accumulated in SKOV-3 xenografts when ZHER2:342-SR-HP1 was injected 4 h earlier. The tumor accumulation of (111)In/(125)I-HP2 was negligible without ZHER2:342-SR-HP1 pre-injection. The uptake of (111)In-HP2 in SKOV-3 xenografts was 19±2 %ID/g at 1 h after injection. The uptake in blood and kidneys was approximately 50- and 2-fold lower, respectively. In conclusion, we have shown that the use of Affibody-based PNA-mediated pretargeting enables specific delivery of radiometals to tumors and provides higher radiometal concentration in tumors than in kidneys.
Involvement of the Trigeminal Motor System in Brain Stem Self-Stimulation and Stimulation-Induced Behavior (1979)

Anatomical and behavioral correlates of intracranial self-stimulation (ICSS) at sites in the pons suggest the involvement of the trigeminal motor system in brain stimulation reward. 90% of the electrodes terminating in or dorsal to the trigeminal motor nucleus supported ICSS. Stimulation through these ICSS electrodes was usually accompanied by a display of repetitive jaw movement in the period following brain stimulation. There appeared to be a close relation between post-stimulation jaw movement and ICSS. In the motor nucleus there was a positive linear relationship between current intensity and duration of jaw movement. Optimal current intensities for ICSS induced long periods of jaw movement. Extensive lesions of the dorsal pons which included the locus ceruleus had no effect on ICSS in the trigeminal motor system. Therefore it seems unlikely that ICSS in the trigeminal system is mediated by noradrenergic neurons located in the dorsal pontine area. These data suggest that a centripetal analysis of ICSS sites along pathways afferent to the trigeminal motor system may lead to a more complete description of the anatomical correlates of brain stimulation reward. The functional implications of a trigeminal reinforcement mechanism are discussed.
A mechanistic role for the chromatin modulator, NAP1L1, in pancreatic neuroendocrine neoplasm proliferation and metastases (2014)

NAP1L1 is over-expressed in pancreatic neuroendocrine neoplasm metastases and epigenetically promotes cell proliferation through regulation of p57 (Kip2) promoter methylation.
The Ferromagnetic Kondo Model for Manganites: Phase Diagram and Charge Segregation Effects (1997)

The phase diagram of the ferromagnetic Kondo model for manganites is investigated using computational techniques. In clusters of dimensions 1 and 2, Monte Carlo simulations in the limit where the localized spins are classical show a rich low temperature phase diagram with three dominant regions: (i) a ferromagnetic phase, (ii) phase separation between hole-poor antiferromagnetic and hole-rich ferromagnetic domains, and (iii) a phase with incommensurate spin correlations. Possible experimental consequences of the regime of phase separation are discussed. Studies using the Lanczos algorithm and the Density Matrix Renormalization Group method applied to chains with localized spin 1/2 (with and without Coulombic repulsion for the mobile electrons) and spin 3/2 degrees of freedom give results in excellent agreement with those in the spin localized classical limit. The Dynamical Mean Field ($D=\infty$) approximation was also applied to the same model. At large Hund coupling phase separation and ferromagnetism were identified, again in good agreement with results in low dimensions. In addition, a Monte Carlo study of spin correlations allowed us to estimate the critical temperature for ferromagnetism $T_c^{FM}$ in 3 dimensional clusters. It is concluded that $T_c^{FM}$ is compatible with current experimental results.
Quantitative Separation of the Enantiomeric Pairs of the Pheromone 2‐Ethyl‐1,6‐dioxaspiro[4.4]nonane by Complexation Chromatography on an Optically Active Metal Complex (1980)

On use of a new chiral separating phase, complexation gas chromatography effectively resolved the synthetic aggregation pheromone of Pityogenes chalcographus on a nickel (II) bis((R)-pulegonate) complex into its four configurational isomers (see right, R = C2H5).
Viral transcription is necessary and sufficient for vesicular stomatitis virus to inhibit maturation of small nuclear ribonucleoproteins (1989)

Infection of baby hamster kidney cells with vesicular stomatitis virus (VSV) results in the accumulation of immature U1 and U2 small nuclear ribonucleoproteins (snRNPs) that contain precursor U RNAs and at least some of the proteins specific for U1 and U2 snRNAs but lack the Sm complex of proteins that is common to these U snRNAs. The VSV function required for this effect is not known, but direct inhibition of cellular transcription did not alter the maturation of U1 and U2 snRNPs. On the other hand, viral transcription but not viral translation was required to inhibit U1 and U2 snRNP maturation. Temperature shift experiments with the mutant G114 showed that ongoing viral transcription was necessary, but that viral mRNA was not required for this inhibition. Furthermore, the VSV function involved in the inhibition of maturation of U1 and U2 snRNPs had a small UV target size of approximately 10 to 20 nucleotides. We demonstrate that temperature-sensitive mutants of VSV can be used as a tool to initiate the assembly of snRNPs in infected cells. These results are compatible with the suggestion that perturbation of snRNP metabolism by VSV precedes and is distinct from the effect of VSV on cellular RNA synthesis, although VSV leader RNA may be involved in both these functions.