gebhart/patrepeval huggingface dataset:
Influence of Electronegativity on Reactions Involving Triangular Three-Center, Two-Electron Bonds:  The −2hβ Effect (2002)

The HMO method, which describes the variation of bond energies of two-center, two-electron bonds AB with an electronegativity difference Δχ by a hyperbolic relationship, is investigated and suggests that the bond energies of triangular three-center, two-electron bonds of the type AB2 are described by a similar hyperbolic relationship that is displaced along the Δχ axis by the resonance integral βBB. The mutual relationship of these idealized bond-energy/electronegativity difference curves provides a basis for rationalizing the observed influence of electronegativity on reactions involving three-center bonds in the gas and liquid phases. Using this analysis, the contribution of the B−B interaction to the strength of a three-center bond AB2 can be dissected into two discrete components. These are (i) the extra “aromatic” energy due to cyclic conjugation of two electrons and (ii) a contribution that is determined by the electronegativity difference Δχ (proportional to the difference in the Coulomb integrals, i.e., αA − αB = h) and by the resonance integral βBB for the B−B interaction. We refer to the second contribution, which can be positive or negative depending upon the value of h, as the −2hβ effect, as it is this term that characterizes the second contribution in the bond-energy equations.
Determining the Area under the ROC Curve for a Binary Diagnostic Test (2000)

The authors provide a simple calculation for the unbiased estimation of the area under the ROC curve for a binary diagnostic test or a continuously valued test result that is effectively used in a binary way. The formula described can be used to interpret the discriminative ability of a diagnostic test.
Accurate application progress analysis for large-scale parallel debugging (2014)

Debugging large-scale parallel applications is challenging. In most HPC applications, parallel tasks progress in a coordinated fashion, and thus a fault in one task can quickly propagate to other tasks, making it difficult to debug. Finding the least-progressed tasks can significantly reduce the effort to identify the task where the fault originated. However, existing approaches for detecting them suffer low accuracy and large overheads; either they use imprecise static analysis or are unable to infer progress dependence inside loops. We present a loop-aware progress-dependence analysis tool, Prodometer, which determines relative progress among parallel tasks via dynamic analysis. Our fault-injection experiments suggest that its accuracy and precision are over 90% for most cases and that it scales well up to 16,384 MPI tasks. Further, our case study shows that it significantly helped diagnosing a perplexing error in MPI, which only manifested at large scale.
Restoring the 3D vestibulo-ocular reflex via electrical stimulation: The Johns Hopkins multichannel vestibular prosthesis project (2011)

Bilateral loss of vestibular sensation causes difficulty maintaining stable vision, posture and gait. An implantable prosthesis that partly restores normal activity on branches of the vestibular nerve should improve quality of life for individuals disabled by this disorder. We have developed a head-mounted multichannel vestibular prosthesis that restores sufficient semicircular canal function to partially recreate a normal 3-dimensional angular vestibulo-ocular reflex in animals. Here we describe several parallel lines of investigation directed toward refinement of this approach toward eventual clinical application.
Changes in mechanical loading lead to tendonspecific alterations in MMP and TIMP expression: influence of stress deprivation and intermittent cyclic hydrostatic compression on rat supraspinatus and Achilles tendons (2008)

Background Tendinopathy commonly occurs in tendons with large in vivo loading demands like the Achilles tendon (AT) and supraspinatus tendon (SST). In addition to differences in their local anatomic environment, these tendons are designed for different loading requirements because of the muscles to which they attach, with the AT experiencing higher loads than the SST. One possible factor in the progression of tendinopathy is the interplay between mechanical loading and the regulation of enzymes that degrade the extracellular matrix (matrix metalloproteinases (MMPs)) and their inhibitors (tissue inhibitor of metalloprotienases (TIMPs)). Thus, overuse injuries may have different biological consequences in tendons designed for different in vivo loading demands. Aim In this study, the tendon-specific regulation of MMP-13, MMP-3 and TIMP-2 expression in rat AT and SST exposed to two different mechanical environments was investigated. Methods Rat AT and SST were exposed to stress deprivation (ie, detached from attachments) and intermittent cyclic hydrostatic compression (with attachments intact). Levels of MMP-13, MMP-3 and TIMP-2 mRNA were evaluated in time-zero control, attached, stressdeprived and “compressed” tendons. Results Stress deprivation led to elevated expression of MMP-13, MMP-3 and TIMP-2 in both tendons, although the magnitude of the increase was greater for the SST than the AT. Intermittent cyclic hydrostatic compression of attached tendons increased expression of MMP-13 in the SST, but not the AT. Conclusions The results of this study suggest that stress deprivation may be one contributor to the progression of tendinopathy in AT and SST, where the tendon designed for the lower in vivo loading demand (SST) was the most affected by a change in mechanical loading. The unique upregulation of MMP-13 with hydrostatic compression supports the impingement injury theory for rotator cuff tears.
Dynamic body potential variation in SOI MOSFETs: Physics, model and applications (2009)

International audience
Vector Precoding for Gaussian MIMO Broadcast Channels: Impact of Replica Symmetry Breaking (2010)

The so-called "replica method" of statistical physics is employed for the large system analysis of vector precoding for the Gaussian multiple-input multiple-output (MIMO) broadcast channel. The transmitter is assumed to comprise a linear front-end combined with nonlinear precoding, that minimizes the front-end imposed transmit energy penalty. Focusing on discrete complex input alphabets, the energy penalty is minimized by relaxing the input alphabet to a larger alphabet set prior to precoding. For the common discrete lattice-based relaxation, the problem is found to violate the assumption of replica symmetry and a replica symmetry breaking ansatz is taken. The limiting empirical distribution of the precoder's output, as well as the limiting energy penalty, are derived for one-step replica symmetry breaking. For convex relaxations, replica symmetry is found to hold and corresponding results are obtained for comparison. Particularizing to a "zero-forcing" (ZF) linear front-end, and non-cooperative users, a decoupling result is derived according to which the channel observed by each of the individual receivers can be effectively characterized by the Markov chain u-x-y, where u, x, and y are the channel input, the equivalent precoder output, and the channel output, respectively. For discrete lattice-based alphabet relaxation, the impact of replica symmetry breaking is demonstrated for the energy penalty at the transmitter. An analysis of spectral efficiency is provided to compare discrete lattice-based relaxations against convex relaxations, as well as linear ZF and Tomlinson-Harashima precoding (THP). Focusing on quaternary phase shift-keying (QPSK), significant performance gains of both lattice and convex relaxations are revealed compared to linear ZF precoding, for medium to high signal-to-noise ratios (SNRs). THP is shown to be outperformed as well.
Open Source Software Infrastructure for Computational Biology and Visualization (2005)

The CMISS software package is used in many biological research areas for multiscale computational biology and visualization. Some major components of this suite have recently been released under an open source license, specifically modules for field storage, 3D graphics, mathematical field operators and image processing. Interfaces are being developed to facilitate integration with other applications and the Internet.
NF-κB is involved in SHetA2 circumvention of TNF-α resistance, but not induction of intrinsic apoptosis (2010)

Treatment of cancer with tumor necrosis factor-alpha (TNF-alpha) is hindered by resistance and toxicity. The flexible heteroarotinoid, SHetA2, sensitizes resistant ovarian cancer cells to TNF-alpha-induced extrinsic apoptosis, and also induces intrinsic apoptosis as a single agent. This study tested the hypothesis that nuclear factor-kappaB (NF-kappaB) is involved in SHetA2-regulated intrinsic and extrinsic apoptosis. SHetA2 inhibited basal and TNF-alpha-induced or hydrogen peroxide-induced NF-kappaB activity through counter-regulation of upstream kinase (IkappaB kinase) activity, inhibitor protein (IkappaB-alpha) phosphorylation, and p-65 NF-kappaB subunit nuclear translocation, but independently of reactive oxygen species generation. Ectopic over-expression of p-65, or treatment with TNF-alpha receptor 1 (TNFR1) small interfering RNA or a caspase-8 inhibitor, each attenuated synergistic apoptosis by SHetA2 and TNF-alpha, but did not affect intrinsic apoptosis caused by SHetA2. In conclusion, NF-kappaB repression is involved in SHetA2 circumvention of resistance to TNF-alpha-induced extrinsic apoptosis, but not in SHetA2 induction of intrinsic apoptosis.
Diffusion of Glucose, Insulin, Inulin, and Evans Blue Protein into Thoracic Duct Lymph of Man* (1967)

Immunoreactive insulin, like inulin, quickly equilibrates with interstitial fluid, as evidenced by recovery in thoracic duct lymph in man. Insulin-like activity not accounted for by immunoreactive insulin behaves as a large protein and is confined to the vascular compartment.
CONTENT OF ATP IN CULTIVATED NEURONS AND ASTROCYTES EXPOSED TO BALANCED AND POTASSIUM‐RICH MEDIA (1970)

Abstract— The content of ATP was measured in neurons from dorsal root ganglia and in cortical and spinal astrocytes with the luciferase method. No ATP could be demonstrated in the cortical cells but in the dorsal root neurons and spinal astrocytes an average amount of 7·9 and 11·9 × 10 −15 mol per cell respectively was found. An increase in the external potassium concentration had no effect on the content of ATP in neurons (7·1 × 10 −15 mol/cell) but led to a significant ( P < 0·005) decline to 6·4 × 10 −15 mol per cell in the astrocytes.
Fault Tolerance in Distributed Systems (1994)

1. Introduction. Basic Concepts and Definitions. Phases in Fault Tolerance. Overview of Hardware Fault Tolerance. Reliability and Availability. Summary. 2. Distributed Systems. System Model. Interprocess Communication. Ordering of Events and Logical Clocks. Execution Model and System State. Summary. 3. Basic Building Blocks. Byzantine Agreement. Synchronized Clocks. Stable Storage. Fail Stop Processors. Failure Detection and Fault Diagnosis. Reliable Message Delivery. Summary. 4. Reliable, Atomic, and Causal Broadcast. Reliable Broadcast. Atomic Broadcast. Causal Broadcast. 5. Recovering A Consistent State. Asynchronous Checkpointing and Rollback. Distributed Checkpointing. Summary. 6. Atomic Actions. Atomic Actions and Serializability. Atomic Actions in a Centralized System. Commit Protocols. Atomic Actions on Decentralized Data. Summary. 7. Data Replication And Resiliency. Optimistic Approaches. Primary Site Approach. Resiliency with Active Replicas. Voting. Degree of Replication. Summary. 8. Process Resiliency. Resilient Remote Procedure Call. Resiliency with Asynchronous Communication. Resiliency with Synchronous Message Passing. Total Failure and Last Process to Fail. Summary. 9. Software Design Faults. Approaches for Uniprocess Software. Backward Recovery in Concurrent Systems. Forward Recovery in Concurrent Systems. Summary. Bibliography.
High‐frequency comparison of gic‐simulated inductance circuits (1974)

Abstract It is shown that there is a significant difference in the high‐frequency behaviour of two well‐known generalized immittance converter realizations of simulated inductance. One of the realizations yields a Q factor that is highly sensitive to mismatch of amplifier bandwidths whereas the alternative realization can be designed to give a Q factor that is highly insensitive to this mismatch.
High Efficiency Microwave Excitation of Light Sources* (1956)

An electrodeless discharge tube was mounted as a section of the inner conductor of a tuneable length of coaxial line. This made possible essentially perfect matching between the oscillator and the light source tube and permitted operation in a cavity of small diameter, a feature of particular importance where the light source needs to run between the poles of an electromagnet. To avoid the wastage of power incurred when an attenuator is placed between the oscillator and the load, the oscillator was protected by a cutoff relay activated by reflected power. The maximum intensity obtained for the Hg 5461 A line was 0.025 watt/cm2/steradian under conditions for which the line, although wider than 1010 cps, looked sharp when observed visually through a spectroscope. Under conditions for which the width was 8×103 cps an intensity of 0.004 watt/cm2/steradian was observed.
Application of a Static Fluorescence-Based Cytometer: The Cellscan in Clinical Immunology (2006)

The CellScan system is a laser scanning cytometer which enables repetitive fluorescence intensity (FI) and polarization (FP) measurements in living cells, as a means of monitoring lymphocyte activation. By monitoring FP changes in peripheral blood lymphocytes (PBL) following exposure to antigenic stimuli, the CellScan may have a role in the diagnosis of autoimmune diseases. Monitoring changes in FI and FP in PBLs from patients with atherosclerosis following exposure to various stimuli, has illustrated the role of the immune system in the atherosclerotic process. The CellScan has also been evaluated as a diagnostic tool for drug-induced allergy, based on FP reduction in PBLs following incubation with the suspected drugs. FI and FP changes in cancer cells have been found to correlate with the cytotoxic effect of different anti-neoplastic drugs, illustrating the potential role of the CellScan system in clinical oncology. In conclusion, the CellScan is a promising new tool with a variety of applications in cell biology, immunology, cancer research and clinical pharmacology.
Author response: Heritable capture of heterochromatin dynamics in Saccharomyces cerevisiae (2015)

Single-cell and single-molecule analyses of transient gene expression revealed hitherto unrecognized dynamics in heterochromatin function and defined novel roles for a heterochromatin establishment factor and an understudied sirtuin.
Relevant clinical end points in biphosphonate trials. (1998)

Article Tools Article Tools OPTIONS & TOOLS Export Citation Track Citation Add To Favorites Rights & Permissions COMPANION ARTICLES No companion articles ARTICLE CITATION DOI: 10.1200/JCO.1998.16.9.3204 Journal of Clinical Oncology - published online before print September 21, 2016 PMID: 9738595 Relevant clinical end points in biphosphonate trials. J R BerensonxJ R BerensonSearch for articles by this author , P MajorxP MajorSearch for articles by this author , G HortabagyixG HortabagyiSearch for articles by this author https://doi.org/10.1200/JCO.1998.16.9.3204 PDF "Relevant clinical end points in biphosphonate trials.." Journal of Clinical Oncology, 16(9), pp. 3204–3205© 1998 by American Society of Clinical Oncology
Contrast enhancement in polarimetric imaging with correlated noise fluctuations (2015)

Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter Facebook Reddit LinkedIn Tools Icon Tools Reprints and Permissions Cite Icon Cite Search Site Citation Swapnesh Panigrahi, Julien Fade, Mehdi Alouini; Contrast enhancement in polarimetric imaging with correlated noise fluctuations. AIP Conf. Proc. 13 January 2015; 1641 (1): 305–312. https://doi.org/10.1063/1.4905992 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAIP Publishing PortfolioAIP Conference Proceedings Search Advanced Search |Citation Search
Context-driven Near-term Intention Recognition (2004)

Recognizing the intention of others in real time is a critical aspect of many human tasks. This article describes a technique for interpreting the near-term intention of an agent performing a task in real time by inferring the behavioral context of the observed agent. Equally significant, the knowledge used in this approach can be captured semi-automatically through observation of an agent performing tasks on a simulator in the context to be recognized. A hierarchical, template-based reasoning technique is used as the basis for intention recognition, where there is a one-to-one correspondence between templates and behavioral contexts or sub-contexts. In this approach, the total weight associated with each template is critical to the correct selection of a template that identifies the agent's current intention. A template's total weight is based on the contributions of individual weighted attributes describing the agent's state and its surrounding environment. The investigation described develops and implements a novel means of learning these weight assignments by observing actual human performance. It accomplishes this using back-propagation neural networks and fuzzy sets. This permits early discrimination between different pre-categorized behavioral contexts/sub-contexts on the human-controlled agent such as a military or passenger vehicle. We describe an application of this concept and the experimentation to determine the viability of this approach.
The Polarization of Type V Bursts (1980)

From observations with the Culgoora spectropolarimeter operating in the frequency range 24–200 MHz, we find that Type V bursts are often polarized in the opposite sense from the preceding Type III bursts. We present here the results of a statistical study of how frequently this occurs and the relationship of such polarization reversals to the position of the source on the disk of the Sun. We then examine two possible reasons for the reversal of polarization. In a paper published elsewhere (Dulk et al., 1979) we give a more detailed description and include observations of source sizes, positions and brightness temperatures of Type III-V bursts.
Iron Deficiency Anemia Prevalence at First Stroke or Transient Ischemic Attack (2012)

These findings support the initiation of a prospective case control study to investigate IDA as a risk factor for ischemic stroke in elderly patients.
Role of cytokines in endometrium and at the fetomaternal interface (1994)

Cytokines were first recognized as factors involved in the immune responses. However, emerging evidence suggests that cytokines serve as the unanimous language through which cells in organ systems as diverse as hypothalamus to endometrium communicate. Evidence for the participation of these factors in the normal function of the endometrium and uteroplacental unit and development of the embryo is being recognized. This review will highlight the significant insight gained over the past several years for the role of cytokines in the field of reproductive biology. Major emphasis will be placed on interleukins, tumour necrosis factor-α, transforming growth factors, colony stimulating factors and interferon-gamma.
Physiological calcium ion concentration and a cholinergic drug on activity of particulate guanylate cyclase in guinea pig taenia caecum. (1981)

The microsomal fraction derived from the taenia caecum of guinea pigs was used as particulate guanylate cyclase preparation. The guanylate cyclase activity was not influenced by butyltrimethylammonium bromide and Ca2+ (4.0 to 24 X 10-7 M). The results suggest that the particulate guanylate cyclase is not activated by the drug-receptor interaction and also by the increase of intracellular Ca2+ concentration. Therefore, the increase of tissue level of cyclic GMP brought about in the guinea pig taenia caecum might be due to activation of soluble guanylate cyclase following the increase in the intracellular Ca2+ concentration.
Exact Dynamic Support Tracking with Multiple Measurement Vectors using Compressive MUSIC (2011)

Dynamic tracking of sparse targets has been one of the important topics in array signal processing. Recently, compressed sensing (CS) approaches have been extensively investigated as a new tool for this problem using partial support information obtained by exploiting temporal redundancy. However, most of these approaches are formulated under single measurement vector compressed sensing (SMV-CS) framework, where the performance guarantees are only in a probabilistic manner. The main contribution of this paper is to allow \textit{deterministic} tracking of time varying supports with multiple measurement vectors (MMV) by exploiting multi-sensor diversity. In particular, we show that a novel compressive MUSIC (CS-MUSIC) algorithm with optimized partial support selection not only allows removal of inaccurate portion of previous support estimation but also enables addition of newly emerged part of unknown support. Numerical results confirm the theory.
ChemInform Abstract: Rubiginoside, a Farnesyl Glycoside from Lepisanthes rubiginosa. (1999)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Hardware implementation of a Particle Filter for location estimation (2010)

In this paper we present the hardware implementation of a Particle Filter for location estimation. Based on distance information to static network nodes, the filter estimates the three-dimensional position of a mobile network node. The design has been derived from a set of formal operation properties and synthesized for an FPGA prototype platform. Accessed through a serial interface, it can be used as a location estimation core from microcontrollers with low computational power. The implemented models for state transition and measurements can be re-parameterized during operation. Due to the chosen design approach these models can also easily be modified or exchanged in order to match the application needs. The correct functionality of the implementation has been shown using real time-of-flight based distance measurements. Therefore, the prototype platform has been integrated in an existing IEEE 802.15.4a compliant wireless network infrastructure.