gebhart/patrepeval huggingface dataset:
Global Citizenship Education:: Towards Globalizing Culture of Rights and Responsibilities (2015)

It is heartening to see more and more international debates about the gravity of the issues confronting humanity with unprecedented global social, political and ecological dangers. There are very few places on the planet, which are not in a state of emergency in one way or the other. An Attempt is made here to highlight the urgent need for reimagining global citizenship education and global citizens in order to transcend the present anthropocentric development and reach out to all those unheard voices, whose precarious lives are under the clutches of patriarchal nature of unsustainable development. Understanding the true nature of education, universal values of democracy, rights and responsibilities evolved from rich experience of civilizations, philosophers, thinkers and practitioners is invaluable treasure in redefining culturally sensitive global citizenship education from which emerge conscious ‘global humane beings’. What we need in the world of globalization is globalization of culture of responsibility. Globalizing responsibility lies in the hearts of global citizens to gather all the positive forces of compassion and non-violence we can, of whatever origin, whatever nature, and to nurture, enrich and propagate them like luminous seeds of hope that ultimately leads to ecologically sustainable societies.
Analysis of the Functions of Herpes Simplex Virus Type 1 Regulatory Protein ICP0 That Are Critical for Lytic Infection and Derepression of Quiescent Viral Genomes (2009)

Herpes simplex virus type 1 (HSV-1) immediate-early regulatory protein ICP0 is important for stimulating the initiation of the lytic cycle and efficient reactivation of latent or quiescent infection. Extensive investigation has suggested several potential functions for ICP0, including interference in the interferon response, disruption of functions connected with PML nuclear bodies (ND10), and inhibition of cellular histone deacetylase (HDAC) activity through an interaction with the HDAC-1 binding partner CoREST. Analysis of the significance of these potential functions and whether they are direct or indirect effects of ICP0 is complicated because HSV-1 mutants expressing mutant forms of ICP0 infect cells with widely differing efficiencies. On the other hand, transfection approaches for ICP0 expression do not allow studies of whole cell populations because of their limited efficiency. To overcome these problems, we have established a cell line in which ICP0 expression can be induced at levels pertaining during the early stages of HSV-1 infection in virtually all cells in the culture. Such cells enable 100% complementation of ICP0-null mutant HSV-1. Using cells expressing the wild type and a variety of mutant forms of ICP0, we have used this system to analyze the role of defined domains of the protein in stimulating lytic infection and derepression from quiescence. Activity in these core functions correlated well the ability of ICP0 to disrupt ND10 and inhibit the recruitment of ND10 proteins to sites closely associated with viral genomes at the onset of infection, whereas the CoREST binding region was neither sufficient nor necessary for ICP0 function in lytic and reactivating infections.
<i>cla</i>MP Tag: A Versatile Inline Metal-Binding Platform Based on the Metal Abstraction Peptide (2014)

Molecularly targeted research and diagnostic tools are essential to advancing understanding and detection of many diseases. Metals often impart the desired functionality to these tools, and conjugation of high-affinity chelators to proteins is carried out to enable targeted delivery of the metal. This approach has been much more effective with large lanthanide series metals than smaller transition metals. Because chemical conjugation requires additional processing and purification steps and yields a heterogeneous mixture of products, inline incorporation of a peptide tag capable of metal binding is a highly preferable alternative. Development of a transition metal binding tag would provide opportunity to greatly expand metal-based analyses. The metal abstraction peptide (MAP) sequence was genetically engineered into recombinant protein to generate the claMP Tag. The effects of this tag on recombinant epidermal growth factor (EGF) protein expression, disulfide bond formation, tertiary structural integrity, and transition metal incorporation using nickel were examined to confirm the viability of utilizing the MAP sequence to generate linker-less metal conjugates.
Pocket-size PEMs (2000)

A recent study by Joan Ogden at Princeton University’s Center for Energy and Environmental Studies tabulated a range of published estimates for the manufacturing costs of mass-produced auto fuel cell systems. The banded-structure membrane fuel cell, from Fraunhofer ISE, draws off voltage at the endplates through an integrated series connection that ties together individual cells. The typical proton exchange membrane (PEM), fuel cell consists of a series of stacked individual cells, with each cell composed of a flow field plate and a membrane electrode assembly. An air breather PEM fuel cell from DCH Technology distributes hydrogen to the flow fields through a central sleeve, while air at atmospheric pressure comes in through the sides. One of the benefits of Manhattan Scientifics’ circuit board approach is the ability of an electrode to act as a ‘preferential molecular filter’. Fraunhofer Institute scientists have been at work on a banded-structure membrane fuel cell. This device holds five-unit cells on a single plate connected as a series circuit.
La búsqueda de la igualdad a través de las políticas educativas: alcances y límites (2005)

Este artículo examina el papel de la educación en la reducción de la desigualdad social y económica. Aunque la relación positiva entre el nivel educativo de un individuo y su sueldo sugiere que la igualación del acceso a educación resultará en una distribución económica más semejante, estructuras sociales y económicas muy desiguales pueden disminuir el poder del sistema educacional para aumentar la igualdad. Dos puntos claves emergen de este discurso: (1) La única manera de reducir la desigualdad social y económica es seguir políticas que igualen con eficacia la distribución de recursos y riquezas en la sociedad y (2) la calidad de la educación y el acceso a la misma puede tener un efecto significativo sobre la desigualdad económica y social. \nEl autor examina varias reformas educativas y cómo éstas pueden o no contribuir a una mayor igualdad en la distribución de la educación y, por tanto, a una mayor igualdad económica y social. Las reformas menos eficaces incluyen reformas ¿estructurales¿ como la descentralización y la privatización. Reformas para mejorar la calidad de los profesores¿como aumentar las horas que los profesores enseñan, igualar la distribución de la calidad de los profesores, y aumentar la capacidad de los profesores¿han demostrado conseguir mayor igualdad educacional. Aunque estas reformas son más costosas y políticamente más difíciles que otras que se han implementado durante los últimos veinte años, representan la mejor oportunidad para hacer que la educación aumente la igualdad social y económica.
Tree View Editing Learning Object Metadata (2005)

An international association advancing the multidisciplinary study of informing systems. Founded in 1998, the Informing Science Institute (ISI) is a global community of academics shaping the future of informing science.
Infection of the surgical site after arthroplasty of the hip (2005)

We wished to estimate the incidence of surgical-site infection (SSI) after total hip replacement (THR) and hemiarthroplasty and its strength of association with major risk factors. The SSI surveillance service prospectively gathered clinical, operative and infection data on inpatients from 102 hospitals in England during a four-year period. The overall incidence of SSI was 2.23% for 16,291 THRs, 4.97% for 5769 hemiarthroplasty procedures, 3.68% for 2550 revision THRs and 7.6% for 198 revision hemiarthroplasties. Staphylococcus aureus was identified in 50% of SSIs; 59% of these isolates were methicillin-resistant (MRSA). In the single variable analysis of THRs, age, female gender, American Society of Anesthesiologists (ASA) score, body mass index, trauma, duration of operation and pre-operative stay were significantly associated with the risk of SSI (p < 0.05). For hemiarthroplasty, the ASA score and age were significant factors. In revision THRs male gender, ASA score, trauma, wound class, duration of operation and pre-operative stay were significant risk factors. The median time to detection of SSI was eight days for superficial incisional, 11 days for deep incisional and 11 days for joint/bone infections. For each procedure the mean length of stay doubled for patients with SSI. The multivariate analysis identified age group, trauma, duration of operation and ASA score as significant, independent risk factors for SSI. There was significant interhospital variation in the rates of SSI. MRSA was the most common pathogen to cause SSI in hip arthroplasty, especially in patients undergoing hemiarthroplasty, but coagulase-negative Staph. aureus may be more important in deep infections involving the joint.
Challenges and Opportunities for Change in Food Marketing to Children and Youth (2013)

The childhood obesity epidemic is an urgent public health problem. The most recent data available show that nearly 19 percent of boys and about 15 percent of girls aged 2-19 are obese, and almost a third of U.S. children and adolescents are overweight or obese (Ogden et al., 2012). The obesity epidemic will continue to take a substantial toll on the health of Americans. In the midst of this epidemic, children are exposed to an enormous amount of commercial advertising and marketing for food. In 2009, children aged 2-11 saw an average of more than 10 television food ads per day (Powell et al., 2011). Children see and hear advertising and marketing messages for food through many other channels as well, including radio, movies, billboards, and print media. Most notably, many new digital media venues and vehicles for food marketing have emerged in recent years, including Internet-based advergames, couponing on cell phones, and marketing on social networks, and much of this advertising is invisible to parents.The marketing of high-calorie, low-nutrient foods and beverages is linked to overweight and obesity. A major 2006 report from the Institute of Medicine (IOM) documents evidence that television advertising influences the food and beverage preferences, requests, and short-term consumption of children aged 2-11 (IOM, 2006). Challenges and Opportunities for Change in Food Marketing to Children and Youth also documents a body of evidence showing an association of television advertising with the adiposity of children and adolescents aged 2-18. The report notes the prevailing pattern that food and beverage products marketed to children and youth are often high in calories, fat, sugar, and sodium; are of low nutritional value; and tend to be from food groups Americans are already overconsuming. Furthermore, marketing messages that promote nutrition, healthful foods, or physical activity are scarce (IOM, 2006). To review progress and explore opportunities for action on food and beverage marketing that targets children and youth, the IOM's Standing Committee on Childhood Obesity Prevention held a workshop in Washington, DC, on November 5, 2012, titled New Challenges and Opportunities in Food Marketing to Children and Youth.
Design of Vehicle Lamp Control System based on LIN bus (2016)

LIN bus is well adapted in vehicle network for its easier development, and through a LIN-CAN gateway, a LIN network can be mounted to CAN network as a distributed control system. To create the vehicle lamp control system, LIN bus is selected as communication bus, and to control lamp a high side switch is introduced. With a master node capturing signals from switch board, transmitting signals to slave nodes through LIN bus, and slave nodes control high side switch to accomplish lamp control. The system works well based on LIN bus and e-switch, which shows a simple but accurate, effective and reliable lamp control system.
จากทองคำเปลวสคมภรพทธประวต: ความเกยวของกบภมภาคตะวนออกทพบ ในงานจตรกรรมฝาผนงพมายคหลง (2012)

ครสตศกราช 1767 กองทพพมาไดยกทพมาตกรงศรอยธยาและกวาดตอนเทครว ผคนจำนวนมากไปยงบรเวณภาคกลางของพมารวมไปถงชางศลปและนกแสดงละคร เปนทเขาใจกนวาเหตการณนเปนจดเรมตนของอทธพลศลปะไทยทมตอศลปะพมารวมไปถงภาพจตรกรรมฝาผนง อยางไรกด การอพยพยายถนของผคน จากดนแดนรฐไทย ลานนา สบสองปนนา และรฐฉานเขาไปยงพมากเกดขนหลายครงหลายโอกาสกอนการตกรงศรอยธยาในปลายครสตศตวรรษท 18 แลว เครอขายการคาและการแลกเปลยนทางศาสนาระหวางวดตางๆ ไดกอใหเกดเสนทางตดตอกนระหวางพมา อยธยา ลานนา สบสองปนนา และรฐฉาน จงไมนาแปลกใจวาปฏสมพนธอนหลากหลายดงกลาวสงผลกระทบตอการสรางงานศลปะในพมากอนการเขาตกรงศรอยธยาและกวาดตอนชางศลปมายงบรเวณกรงองวะ แนวคดทใชในภาพจตรกรรมฝาผนงพมาซงมาจากเรองราววถชวตและการแตงกายแบบไทยภาคกลางสอถงการพรรณนาและวธการปฏบตทางศาสนาซงพบในดนแดนรฐไต บทความนตองการสำรวจแงมมเหลานในงานจตรกรรมฝาผนงพมาในระหวางศตวรรษท 17 – 19 เพอสบคนการแพรกระจายและผลกระทบเหลานน ตลอดจนวธการอนหลากหลายทงทางดานสงคม ศาสนา และการเมองทเกดขน ในทายทสดจตรกรรมฝาผนงยงแสดงถงมมมองของชาวพมาทมความมนใจในวฒนธรรมของตนแตกพรอมทจะรบเอาเนอหาบางอยางจากภายนอก สวนหนงเนองจากการมศรทธารวมกนในพระพทธศาสนาและความสมพนธทางการเมองทเลอนไหลใน From Gold Leaf to Buddhist Hagiographies: Contact with Regions to the East Seen in Late Burmese Murals. In 1767 the Burmese army sacked the Thai city of Ayutthaya, and multitudes of people were captured and relocated to the Burmese central zone, including artists and theatrical performers. This event has been considered seminal in the emergence of Thai influences on Burmese art, including mural painting. Yet, Burmese deportations of people from the Thai, Lan Na, Sipsong Panna, and Shan States regions occurred on a number of occasions prior to the late eighteenth century attack. And, trade networks and religious exchanges between monasteries formed alternative routes of communication between Burma, Ayutthaya, Lan Na, Sipsong Panna, and the Shan States. Unsurprisingly, such variant interactions had an impact on artistic production in Burma prior to the destruction of Ayutthaya and the relocation of artists to the Ava region. The ideas utilized in Burmese murals range from central Thai elements of style and dress to narratives and methods of religious practice found particularly in Tai regions. This paper explores these aspects in Burmese mural paintings from the seventeenth, eighteenth, and nineteenth centuries in order to suggest the extent and nature of this impact, as well as the various means - social, religious, political - by which it came about. The murals ultimately present a view of a culturally confident Burma readily absorbing external material due in part to shared religious beliefs and fluid political relationships in the region.
Scaling up agent coordination strategies (2001)

Deploying intelligent agents to do peoples' bidding in environments ranging from Internet marketplaces to Mars has received much attention. Exactly what an agent is and in what sense a computational agent can behave intelligently remain the subject of considerable debate. However, most would agree that coordination, an agent's fundamental capability to decide on its own actions in the context of the activities of other agents around it, is a central concern of intelligent agency. The value of an intelligent agent coordination strategy lies in how well it scales along various dimensions of stress. Understanding the agent population, its task environment, and expectations about its collective behavior are central to mapping the space of potential approaches. The paper discusses agent coordination and dimensions of coordination stress.
Relationship between Clinicopathologic Variables in Breast Cancer Overall Survival Using Biogeography-Based Optimization Algorithm (2019)

Breast cancer is the most common cancer among women and is considered a major public health concern worldwide. Biogeography-based optimization (BBO) is a novel metaheuristic algorithm. This study analyzed the relationship between the clinicopathologic variables of breast cancer using Cox proportional hazard (PH) regression on the basis of the BBO algorithm. The dataset is prospectively maintained by the Division of Breast Surgery at Kaohsiung Medical University Hospital. A total of 1896 patients with breast cancer were included and tracked from 2005 to 2017. Fifteen general breast cancer clinicopathologic variables were collected. We used the BBO algorithm to select the clinicopathologic variables that could potentially contribute to predicting breast cancer prognosis. Subsequently, Cox PH regression analysis was used to demonstrate the association between overall survival and the selected clinicopathologic variables. C-statistics were used to test predictive accuracy and the concordance of various survival models. The BBO-selected clinicopathologic variables model obtained the highest C-statistic value (80%) for predicting the overall survival of patients with breast cancer. The selected clinicopathologic variables included tumor size (hazard ratio [HR] 2.372, p = 0.006), lymph node metastasis (HR 1.301, p = 0.038), lymphovascular invasion (HR 1.606, p = 0.096), perineural invasion (HR 1.546, p = 0.168), dermal invasion (HR 1.548, p = 0.028), total mastectomy (HR 1.633, p = 0.092), without hormone therapy (HR 2.178, p = 0.003), and without chemotherapy (HR 1.234, p = 0.491). This number was the minimum number of discriminators required for optimal discrimination in the breast cancer overall survival model with acceptable prediction ability. Therefore, on the basis of the clinicopathologic variables, the survival prediction model in this study could contribute to breast cancer follow-up and management.
Columnar Supramolecular Architecture Self‐Assembled from <i>S</i><sub>4</sub>‐Symmetric Coordination Nanotubes Encapsulating Neutral Guest Molecules (2003)

Self-cyclization of four HgCl2 units and four ditopic 1,3-bis(benzimidazol-1-ylmethyl)-2,4,6-trimethylbenzene (bbimms) ligands has resulted in the assembly of the neutral nanotube [Hg4Cl8(bbimms)4] containing two compartments which can accomodate DMF and DMSO guest molecules (see picture). Crystal packing arranges all the tubes into an extended pipeline structure.
Possible worlds (2020)

Modality concerns what might or must be the case. Modal expressions are typically intensional. An expression α is intensional just in case the substitution of extensionally equivalent expressions under the scope of a need not preserve truth. Modal realism is the view that modal propositions are grounded in the existence of concrete, non-actual individuals and worlds. The fact that possibilities cannot be worlds has important implications. Indexical expressions are those that are context-sensitive. This includes expressions such as ‘I’, ‘you’, ‘here’, and ‘now’. The role that worlds traditionally played as maximal consistent doxastic states has been assumed by individuals in order to capture the distinctively de se. For every set of worlds there corresponds the set of individuals each of which inhabits one of those worlds.
Selection of low toxic insecticides for phytoseiid predatory mites, Amblyseius cucumeris and Amblyseius fallacis (2003)

This study was conducted to select low toxic insecticides against natural enemies, and to evaluate resistance stability and cross-resistance to resistance strain for the fulfillment of integrated pest management development. Toxicity of imidacloprid and spinosad to Amblyseius cucumeris was relatively low regardless of the adopting test methods. In addition, those to the Amblyseius fallacis was also low by slide dipping method. The slide dipping method was useful to eliminate repellency effect by mites to the tested insecticides. Mortality of A. fallacis to deltamethrin recorded in 1994 and 1999 was 21.6% and 7.4%, respectively. Meanwhile, the permethrin-resistanct strain of A. fallacis was maintained its resistance to deltamethrin. However, the cross-resistance to the newly introduced insecticides namely imidacloprid, fipronil, chlorfenapyr, abamectin, and spinosad. was relatively low.
LPS-induced lung inflammation is linked to increased epithelial permeability: role of MLCK (2005)

The respiratory system is directly exposed to low levels of lipopolysaccharide (LPS), present as a contaminant on airborne particles. In cystic fibrosis, the prevailing data identify structural changes of the airway epithelium, as well as tight junction dilatation. This study was aimed at determining the contribution of myosin light chain kinase to maintaining airway epithelium barrier integrity in the lung inflammatory response to LPS in rats. The effects of the selective myosin light chain kinase inhibitor, 5-iodonaphthalene-1-sulphonyl-homopiperazine (ML-7), were evaluated: 1) on pulmonary inflammation and airway epithelium barrier permeability alterations induced by intra-tracheal LPS from Pseudomonas aeruginosa; and 2) on levels of the phosphorylated form of the myosin light chain, which is increased in a human airway epithelial cell line (NCI-H292) and tracheal tissue after LPS exposure. The results show that LPS increased airway epithelium barrier paracellular permeability and lung inflammation, and that pre-treatment with ML-7 inhibited both effects. This effect of ML-7 was associated with the inhibition of phosphorylated myosin light chain in both NCI-H292 cells and tracheal tissue. The data, obtained using in vivo and in vitro approaches, demonstrate a key role for myosin light chain kinase in lung inflammation, and suggest that myosin light chain kinase could be a potential target for novel drugs intended for relief of lung injury.
The possibility of high-energy-storage lasers using the auroral and transauroral transitions of column-VI elements (1976)

An analysis of laser systems involving the auroral and transauroral transitions of photolytically excited column-VIA elements is given. Excitation mechanisms, kinetic processes, and collisionally stimulated radiation are examined. Photolytic production of the VIA 1S metastable using rare-gas excimer radiation is emphasized. Oxygen at 5577 Å, sulfur at 7727 and 4589 Å, and possibly selenium at 4888 Å appear as attractive candidates suitable for high-energy-storage short-pulse applications.
<i>Phytophthora infestans</i> : the plant (and <i>R</i> gene) destroyer (2008)

Phytophthora infestans remains a problem to production agriculture. Historically there have been many controversies concerning its biology and pathogenicity, some of which remain today. Advances in molecular biology and genomics promise to reveal fascinating insight into its pathogenicity and biology. However, the plasticity of its genome as revealed in population diversity and in the abundance of putative effectors means that this oomycete remains a formidable foe.
Measurement configuration optimization for accurate grating reconstruction by Mueller matrix polarimetry (2013)

Due to the rich information provided by the Mueller matrices when the most general conical diffraction configuration is considered, the Mueller matrix polarimetry has demonstrated a great potential in semiconductor manufacturing. As the configurations of the incidence and azimuthal angles have different influences on the measurement accuracy, it is necessary to select an optimal one among the multitude of possible options. We introduce the norm of a configuration error propagating matrix to assess the measurement accuracy for different measurement configurations. The optimal configuration for a Si grating sample was achieved by minimizing the norm of the configuration error propagating matrix. Experimental results show the agreement between the theoretically predicted optimal configuration and the experimental exhibited one obtained by using a dual-rotating compensator Mueller matrix polarimeter and thus demonstrated the validity of the proposed optimization method.