gebhart/patrepeval huggingface dataset:
Direct Current Make and Break Thresholds for Pacemaker Electrodes on the Canine Ventricle (1970)

Thresholds to anodal make, anodal break, cathodal make and cathodal break have been studied throughout the cardiac cycle in 13 dogs under pentobarbital anesthesia. Unipolar direct current pulses were applied through epicardial pacemaker electrodes to the left ventricle. Make and break responses were separated by letting the break and make occur in the refractory periods of the following and preceding cycle, respectively. Four distinct threshold interval curves were obtained from each of 17 electrodes. The anodal break and cathodal break curves showed an early diastolic dip. Dips were deepest in the anodal break curves. These also had the shortest effective refractory period. Thresholds for cathodal make and anodal make first dipped steeply, then gradually sloped down towards end-diastolic levels. The magnitude of end-diastolic mean threshold values increased in the following order: cathodal make, anodal make, cathodal break, anodal break. Comparison of threshold interval curves for make and break responses with those for shorter rectangular anodal and cathodal curves throughout the cardiac cycle supports the hypothesis that the threshold behavior to a short rectangular pulse is determined by whichever of two thresholdsis lowest: make or break at that particular cycle interval.
Chemistry of the 1,2,4-Thiadiazine Ring System. II. A New Synthesis of 1,2,4,2H-Thiadiazine-3,5(4H,6H)-dione-1,1-dioxide (1959)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTChemistry of the 1,2,4-Thiadiazine Ring System. II. A New Synthesis of 1,2,4,2H-Thiadiazine-3,5(4H,6H)-dione-1,1-dioxideBERNARD E. HOOGENBOOM, RICHARD ABBOTT, LOUIS LOCATELL Jr., and R. L. HINMANCite this: J. Org. Chem. 1959, 24, 12, 1983–1986Publication Date (Print):December 1, 1959Publication History Published online1 May 2002Published inissue 1 December 1959https://pubs.acs.org/doi/10.1021/jo01094a040https://doi.org/10.1021/jo01094a040research-articleACS PublicationsRequest reuse permissionsArticle Views272Altmetric-Citations7LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
A SURVEY OF ELECTROFORMING FOR FABRICATING STRUCTURES (1964)

Several high-strength structures were produced by electroforming, for specific missile and aerospace applications. Several organizations have electroformed nickel with ultimate tensile strengths of 90,000 to 100,000 psi, or more. Tough (notch insensitive), 200,000-psi nickel was electroformed by one or two organizations, but additional information must be developed before such a high strength material can be electroformed consistently in a complexly shaped form. This state-ofthe-art report describes advantages and limitations of electroforming, summarizes available property data of materials, and discusses electroforming conditions that must be maintained for good control of structural properties.
중학생의 부모에 대한 애착, 친구지지와 행동문제 (2004)

This study was to investigate the relationship between parent attachment, peer support and behavior problems of middle school students. The subjects were 591 male and female students in the first and third grade of the middle school and their mothers in Busan. The instruments used for this study were Inventory of Parent Attachment Scale, Peer Support Scale and Behavior Checklist for Adolescents. The results were as follows: 1. The first grade students had stronger attachment on father and mother than third grade. The third grade students had perceived peer support more than first grade. Female students had stronger attachment on mother and perceived peer support more than male students. And there was no significant sex difference in attachment on father. In the case of female students, internalizing and externalizing behavior problems increased grade. But, in the case of male students, there was no grade difference in internalizing and externalizing behavior problems. In the case of first grade students, there was no sex difference in internalizing behavior problems. In the case of first grade students, males had more externalizing behavior problems than females. But in the case of third grade students, females had more externalizing behavior problems than males. 2. As parent`s education level was higher, students had stronger attachment on parents and perceived more peer support. As family income was higher, students had stronger attachment on father and perceived more peer support. 3. In case of female students, parent attachment and peer support were correlated negatively with internalizing and externalizing behavior problems. In case of male students, attachment on fathers and peer support were correlated negatively with internalizing behavior problems, and attachment on mother and peer support were negatively with externalizing behavior problems.
Lactate-Supported Synaptic Function in the Rat Hippocampal Slice Preparation (1988)

The present study was undertaken to examine the possibility that cerebral energy metabolism can be fueled by lactate. As a sole energy substrate, lactate supported normal synaptic function in rat hippocampal slices for hours without any sign of deterioration. Slices that were synaptically silent as a result of glucose depletion could be reactivated with lactate to show normal synaptic function. When slices were exposed to the glycolytic inhibitor iodoacetic acid, lactate-supported synaptic function was unaffected, whereas that supported by glucose was completely abolished. This indicated that lactate was metabolized directly via pyruvate to enter the tricarboxylic acid cycle. Thus, under conditions that lead to lactate accumulation (cerebral ischemia) this "end product" may be a useful alternative as a substrate for energy metabolism.
Fluorescence lifetimes of carbocyanine lipid analogs in phospholipid bilayers (1985)

The fluorescence lifetimes for the 1,1'-dialkyl-3,3,3',3'-tetramethylindocarbocyanine (CNdiI) dyes (N = 12, 18, and 22) in a variety of lipid bilayer membranes were measured. Effects of bilayer physical state, probe chain length, probe concentration, charge, lipid head group, and cholesterol concentration were examined. Even in single-phase membranes these probes did not exhibit single-exponential decays. Rather, the data were fit by biexponential decays with lifetimes of approximately 0.3-0.4 and approximately 0.9-1.3 ns with no significant improvement in chi 2 convergence with the addition of a third component. Average lifetimes were dependent upon lipid phase and to a lesser degree surface charge and the phospholipid head group. In dipalmitoyl-phosphatidylcholine (DPPC)-cholesterol membranes, the C18diI lifetime was sensitive to membrane reorganizations at both 20 and approximately 33 mol % cholesterol. In egg phosphatidylcholine (EPC) bilayers, the C18diI lifetime was essentially independent of its concentration below 1:10(3).
A new non-uniform quantization method based on distribution of compressive sensing measurements and coefficients discarding (2013)

Compressive sensing (CS) is a new method of sampling and compression which has great advantage over previous signal compression techniques. However, its compression ratio is relatively low compared with most of the current coding standards, which means a good quantization method is very important for CS. In this paper, a new method of non-uniform quantization is proposed based on the distribution of CS measurements and coefficients discarding. Firstly, the magnitude of CS measurements is estimated and the low probability measurements are discarded because of their high quantization error. It should be noted that the dropped measurements almost take no effect on the recovery quality because of the equal-weight property of CS samples. Then a nonlinear quantize function based on the distribution of sensed samples is proposed, by which those remained measurements are quantized. The experimental results show that the proposed method can obviously improve the quality of reconstructed image compared with previous methods in terms of the same sampling rate and different reconstruction algorithms.
Four new methods of debittering protein hydrolysates and a fraction of hydrolysates with high content of essential amino acids. (1978)

Extraction of enzymatic protein hydrolysates with azeotropic secondary butyl alcohol (SBA) or aqueous ethanol (AE) or aqueous isopropranol (AI), seems to be an efficient and generally applicable method for removal of bitter compounds. The bitter peptides are concentrated in the alcohol-phase which has an extremely bitter taste. It has a concentration of 40-70 p. 100 essential amino-acids. In the alcohol-phase leucine, isoleucine, phenylalamine and tryptophan were particularly increased. Experiments showed that the bitterness of the alcohol-soluble fraction could be reduced by applying the plastein reaction. A reduction in bitterness of protein hydrolysates could also be achieved by applying hydrophobic interaction chromatography. Of tested gels, hexyl-sepharose was found to be the most effective for debittering of protein hydrolysates.
Experience of One UK Electronic Equipment Supplier With Bite on Engine/Flight Control Systems Over the Past Ten Years — Part 1 (1986)

This paper traces the history of Dowty Electronics' involvement in B.I.T.E. over the last ten years; it describes the techniques used, successes and failures, and customer reactions. Applications include the full authority engine control for the Olympus 593 in Concorde, the high integrity wing flaps controller for the BAe 146 shorthaul jet, the engine spool speed limiter for the RB‐211–524 in the Boeing 747, and the high integrity engine bleed valve controller for the RB‐211–535 in the Boeing 757 aircraft.
Effects of Biotin - rich Functional Food (Whalgichan) on Hair Growth and Biological Stimulation in Rat and Human (2000)

For the development of functional food for hair-growth stimulation, this study has tried an in vivo and clinical test. As an in vivo test male Sprague Dawley rats and as a clinical test 27 baldheaded or loosehaired men were recruited. Before the experiment, the total hair count in 6 ㎟ of the designated area was 46.5. In four weeks and eight weeks of the functional food feeding it increased to 61.8 and 75.3, respectively. Hence the net increase was totaled at 62% in eight weeks. Also, depilation was decreased by 28%. Before the experiment, average hair loss was 65.7. In four weeks and eight weeks of the functional food feeding it decreased to 55.2 and 47.3, respectively. LDL and phospholipids were decreased by 42% and 36%, respectively during that period. However, HDL was increased by 21%. Forty percent of the subjects responded that itching of head skin was reduced and 34% responded to have reduced dandruff. No side-effects among the subjects were examined and no other blood parameters were significantly affected by the diet. The results in this study suggest that biotin-rich functional food may stimulate cholesterol and lipid metabolism and blood flow leading to the growth of new hair and prevention of hair loss.
OS SUECOS ALTERAM AS NORMAS DE TREINAMENTO PARA CORRIDAS DE FUNDO (1957)

[...]
Urokinase‐Type Plasminogen Activator and Insulin‐Like Growth Factor‐Binding Protein 3 mRNA Expression in Endometriotic Lesions and Eutopic Endometrium (2003)

The peritoneal fluid of women with endometriosis contains an increased insulin-like growth factor 1 (IGF-1) bioavailability, which is produced by limited hydrolysis of urokinase-type plasminogen activator (uPA) on IGF-binding protein 3 (IGFBP-3). Recently, IGF-1 was shown to inhibit apoptosis of endometrial-like cells in vitro, suggesting that a microenvironment of increased IGF-1 bioavailability can optimize the survival of endometrial cells grown ectopically. Here the expression of mRNA of IGFBP-3 and uPA in tissue biopsies from eutopic endometrium and endometriotic lesions obtained at laparoscopy from women with endometriosis have been analyzed, and it is documented that both IGFBP-3 and uPA mRNA expression are increased from 3- to 10-fold in endometriotic lesions versus eutopic endometrium. Consequently, the necessary components (uPA and IGFBP-3 expression) of endocrine/autocrine/paracrine enhancement of local IGF bioavailability mediated by uPA hydrolysis of the IGFBP-3 were present in endometriotic lesions. These data possibly explain the origin of the increased content of uPA activity, IGF-1 bioavailability, and NH(2)-truncated forms of IGFBP-3 in the peritoneal fluid of women with endometriosis.
REUNIÓN DE RECTORES (1997)

EL RECTOR DE LA UNIVERSIDAD DE COAHUILA, INGENIERO JOSE MARIA FRAUSTRO SILLER, REALIZO UNA VISITA DE TRABAJO A LA UNAM EL PASADO 2 DE SEPTIEMBRE. SOSTUVO UNA REUNION CON EL RECTOR FRANCISCO BARNES DE CASTRO EN EL SEXTO PISO DE LA TORRE DE RECTORIA, EN LA QUE ESTUVIERON PRESENTES LA DOCTORA DOROTEA BARNES DE CASTRO, DIRECTORA GENERAL DE INTERCAMBIO ACADEMICO, Y EL MAESTRO RAMON VALDES.
[A comprehensive form for the standardized characterization of transgenic rodents: genotype, phenotype, welfare assessment, recommendations for refinement]. (2000)

When "creating" transgenic mouse strains it is not possible to predict their phenotype with certainty, particularly not with respect to welfare. The generation of models for (human) diseases deliberately implies a compromised health ranging from minor (clinically inapparent) to lethal. To ensure animal welfare requirements and apply the criteria of the 3R, a careful phenotype characterisation and welfare assessment has to be done routinely for each newly produced strain, at individual and strain level, starting by the standardised monitoring of founders and their consequent generations. A comprehensive form has been developed for a standardised characterisation of transgenic mouse strains. It is subdivided into basic and detail information. It can be kept up to date continuously in the form of a computerised database, incorporating growing knowledge and experience of the strain. Basic information mainly serves the requirements of housing and breeding facilities as well as the authorities in view of animal welfare measures, detail information mainly serves the interests of research and efficiency.
A review of fungal phytotoxins: from basic studies to practical use (2008)

Recent materials are summarized, pertaining to classification of fungal phytotoxins, methods of their isolation, and assays for biological activity. Producers of phytotoxic substances have been characterized, and the chemical nature of phytotoxins has been subjected to analysis. The review gives consideration to the mechanisms of action of phytotoxins on susceptible plants and the mechanisms of plant resistance to such agents. Other matters discussed include prospects of utilizing basic knowledge of the nature and mechanisms of action of phytotoxins for (1) developing means of plant protection against diseases and weeds and (2) identifying or classifying fungi (chemosystematics).
Endothelial Dysfunction in Normal and Abnormal Glucose Metabolism (2008)

The endothelium is the common target of all cardiovascular risk factors, and functional impairment of the vascular endothelium in response to injury occurs long before the development of visible atherosclerosis. The endothelial cell behaves as a receptor-effector structure which senses different physical or chemical stimuli that occur inside the vessel and, therefore, modifies the vessel shape or releases the necessary products to counteract the effect of the stimulus and maintain homeostasis. The endothelium is capable of producing a large variety of different molecules which act as agonists and antagonists, therefore balancing their effects in opposite directions. When endothelial cells lose their ability to maintain this delicate balance, the conditions are given for the endothelium to be invaded by lipids and leukocytes (monocytes and T lymphocytes). The inflammatory response is incited and fatty streaks appear, the first step in the formation of the atheromatous plaque. If the situation persists, fatty streaks progress and the resultant plaques are exposed to rupture and set the conditions for thrombogenesis and vascular occlusion. Oxidant products are produced as a consequence of normal aerobic metabolism. These molecules are highly reactive with other biological molecules and are referred as reactive oxygen species (ROS). Under normal physiological conditions, ROS production is balanced by an efficient system of antioxidants, molecules that are capable of neutralizing them and thereby preventing oxidant damage. In pathological states, ROS may be present in relative excess. This shift of balance in favor of oxidation, termed 'oxidative stress', may have detrimental effects on cellular and tissue function, and cardiovascular risk factors generate oxidative stress. Both type 1 (insulin-dependent) and type 2 (non-insulin-dependent) diabetic patients have mostly been described under enhanced oxidative stress, and both conditions are known to be powerful and independent risk factors for coronary heart disease, stroke, and peripheral arterial disease. Hyperglycemia causes glycosylation of proteins and phospholipids, thus increasing intracellular oxidative stress. Nonenzymatic reactive products, glucose-derived Schiff base, and Amadori products form chemically reversible early glycosylation products which subsequently rearrange to form more stable products, some of them long-lived proteins (collagen) which continue undergoing complex series of chemical rearrangements to form advanced glycosylation end products (AGEs). Once formed, AGEs are stable and virtually irreversible. AGEs generate ROS with consequent increased vessel oxidative damage and atherogenesis. The impressive correlation between coronary artery disease and alterations in glucose metabolism has raised the hypothesis that atherosclerosis and diabetes may share common antecedents. Large-vessel atherosclerosis can precede the development of diabetes, suggesting that rather than atherosclerosis being a complication of diabetes, both conditions may share genetic and environmental antecedents, a 'common soil'.
Copacamphane, Picrotoxane, and Alloaromadendrane Sesquiterpene Glycosides and Phenolic Glycosides from <i>Dendrobium </i><i>m</i><i>oniliforme</i> (2003)

Seven sesquiterpene glycosides with copacamphane, picrotoxane, and alloaromadendrane sesquiterpene aglyons along with three phenolic glycosides have been isolated from the stems of Dendrobium moniliforme. Among them, dendromonilisides A-D (1-4) were characterized as new compounds, and their structures were determined on the basis of spectral and chemical methods and by X-ray diffraction analysis. The six known compounds were identified as dendrosides A, C, and F, dendromoniliside E, vanilloloside, and acanthoside B. In a preliminary biological test procedure, compounds 1, 3, and vanilloloside were found to stimulate the proliferation of B cells and inhibit the proliferation of T cells in vitro.
System level ASIC design for Hewlett-Packard's low cost PA-RISC workstations (2002)

The system architecture of a low cost PA-RISC workstation is described. This architecture is implemented in Hewlett-Packard's 9000 series 700 workstations. High performance and low cost are achieved through careful system partitioning and appropriate application of integration. The system design involved the development of four ASICs: a memory I/O system controller, a mixing buffer chip, a DRAM address decoder/buffer chip, and a controller for the built-in I/O functions. The system architecture is optimized to maximize performance for workstation workloads which include an emphasis on raw CPU performance, graphics, and I/O throughput.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Absorption by dissolved organic matter of the sea (yellow substance) in the UV and visible domains1 (1981)

This article is in Free Access Publication and may be downloaded using the “Download Full Text PDF” link at right.
LIGHTWEIGHT PRIORITY SCHEDULING SCHEME FOR SMART HOME AND AMBIENT ASSISTED LIVING SYSTEM (2014)

Smart Home and Ambient Assisted Living (SHAAL) systems utilize advanced and ubiquitous technologies including sensors and other devices that are integrated in the residential infrastructure or wearable, to capture data describing activities of daily living and health related events. However, with the introduction of these technology-orientated services come a number of challenges, which to date are still largely unsolved. The management and processing of the large quantities of data generated from multiple sensors is recognized as one of the most significant challenges. Therefore, a simple yet efficient data scheduling scheme is proposed in this paper to manage incoming data packet from the system based on their application types and priorities. The performances of this lightweight context-aware scheme are investigated in a real SHAAL setting under two scenarios; centralized and distributed setups. The experimental results show the proposed scheme offers a promising solution for guaranteeing higher throughput to the high priority data while giving sufficient access to low priority data without introducing much delay impact.
Multiple Reflection Analysis of TDR Signal for Complex Dielectric Spectroscopy (2018)

Most dielectric spectroscopy techniques require careful system calibration, tedious measurement, specially designed probes, precise input source, and some even involved complicated inversion models. This paper proposed a rapid, robust, and model-free multiple reflection analysis (MRA) of time-domain reflectometry (TDR) signals to measure the complex dielectric permittivity (CDP) spectrum. The key to MRA approach is to decompose the first top reflection and the subsequent multiple reflections from TDR signal and to compare their spectral ratio (MRA ratio). This ratio was theoretically derived from the transmission line theory and found to be independent of source function and impedance mismatches in the leading sections. Based on this theoretical formulation, the CDP spectrum can be uniquely inverted from the measured MRA ratio through optimization and an iterated initial guess method. Numerical evaluations and experimental verifications had proven that MRA is a reliable algorithm for measuring CDP spectrum covering 10 MHz-1 GHz. Factors influencing the reliable frequency region were discussed and recommendations on enhancing CDP measurement was proposed for highly dispersive materials. The MRA approach enables dielectric spectroscopy to be conveniently conducted in both laboratory and field, without complicated system setup and calibration.