gebhart/patrepeval huggingface dataset:
Bacterial Attachment to a Specific Wound Site as an Essential Stage in Tumor Initiation by<i>Agrobacterium tumefaciens</i> (1969)

The number of tumors initiated by Agrobacterium tumefaciens strain B6 on primary pinto bean leaves was decreased when cells of an avirulent strain (IIBNV6) were included in the inoculum. With sufficient B6 cells to initiate ca. 50% of the maximal number of tumors per leaf, inhibition was detected at a 1:1 ratio of B6 to IIBNV6 cells and increased linearly with the logarithm of the number of IIBNV6. Varying the number of B6 in the presence of a constant number of IIBNV6 or varying the number of both, while maintaining a constant ratio of B6 to IIBNV6, showed that the inhibition was a function of the absolute concentration of each cell type. The data fit a one-particle dose response curve, which indicates that a single IIBNV6 cell can prevent tumor initiation by a single B6 cell. Inhibition was obtained with mixed inocula and when the addition of IIBNV6 preceded B6, but not when B6 preceded IIBNV6. Heat-inactivated IIBNV6 inhibited, as did ultraviolet or heat-inactivated B6. Several unrelated bacteria and certain strains of Agrobacterium failed to inhibit, whereas other related strains gave inhibition. Attachment of IIBNV6 to a specific would site, thus excluding B6 from the site, is proposed to account for these data. A specific complementary binding of a virulent bacterium to a host wound site exposed by the inoculation procedure is suggested as an essential early event in the crown-gall tumor initiation process.
Hemangioma-thrombocytopenia syndrome; a disseminated intravascular coagulopathy (1975)

A patient who had multiple hemangiomas and for whom results of coagulation studies were consistent with the hemangioma-thrombocytopenia (Kasabach-Merritt) syndrome and a microangiopathic hemolytic process was asymptomatic prior to surgical removal of a lipoma. Postoperatively, she developed bleeding secondary to a disseminated intravascular coagulopathy. Her bleeding was controlled by anticoagulation therapy. A review of the literature provides evidence suggesting that the hemangioma-thrombocytopenia syndrome is due to a disseminated intravascular coagulopathy initiated within the hemangioma. Surgical trauma may precipitate exacerbations of the coagulopathy in these patients and all unnecessary surgical procedures should be avoided.
The Q-bit scheme (1992)

Modern protocols designed for high-speed networks mostly adapt the rate at which packets are transmitted to control the flow of data between a sender and a receiver, and to control the load put upon the underlying network. In this article, the use of rate-adaption to realize 'congestion avoidance', a recently proposed highly sophisticated technique to control overload-conditions in networks is examined. With a simple analytical model of the system, expressions which help to tune it are derived. By directly comparing the resulting system to the well-known DECbit scheme which uses a window to adapt the load it is shown that most of the limitations of this scheme can be eliminated while preserving its advantages. More specific, because of the direct adaption of a rate fairness can be guaranteed in general topologies. This is possible without the need to put the burden of enforcing fairness on the (in a high-speed network already heavily loaded) routers. Finally the system can better adapt to varying packet-sizes, thus offering greater robustness and efficiency when used in real networks.
Dynamic Simulation of Large-Scale Power Systems Using a Parallel Schur-Complement-Based Decomposition Method (2013)

Power system dynamic simulations are crucial for the operation of electric power systems as they provide important information on the dynamic evolution of the system after an occurring disturbance. This paper proposes a robust, accurate and efficient parallel algorithm based on the Schur complement domain decomposition method. The algorithm provides numerical and computational acceleration of the procedure. Based on the shared-memory parallel programming model, a parallel implementation of the proposed algorithm is presented. The implementation is general, portable and scalable on inexpensive, shared-memory, multi-core machines. Two realistic test systems, a medium-scale and a large-scale, are used for performance evaluation of the proposed method.
Introduction (2017)

This introduction presents an overview of the key concepts discussed in the subsequent chapters of this book. The book explores the European core-periphery divergences in the period preceding the crisis (1999–2008). It outlines the evolution of the French economy since the formation of Monetary Union. The book also presents an interpretation of the crisis that differs from the 'consensus narrative', which saw the crisis as a standard balance of payment crisis along the lines of the models applied to the developing countries. It focuses on the internal divides within two countries, Germany and Italy, representative, respectively, of the core and the periphery. The book also focuses on the factors that interrupted the golden age of post-war capitalist development in the late 1960s and early 1970s, and argues that the great inflation of the 1970s, associated with political and social tensions, intertwined discontinuities in the modus operandi of western capitalist countries.
Factor Xa cleavage of fusion proteins (1990)

A method is described for the elimination of non-specific cleavage of fusion proteins by factor Xa. Putative non-specific cleavage sites C-terminal to lysyl residues are blocked by reversible acylation by 3,4,5,6-tetrahydrophthalic anhydride prior to cleavage. After cleavage, the acyl groups are removed quantitatively by exposure to slightly acidic conditions. This method employs no harsh reagents or conditions, and may be generally applicable to factor Xa cleavage of fusion proteins.
A Collaborative Filtering Approach for Protein-Protein Docking Scoring Functions (2011)

A protein-protein docking procedure traditionally consists in two successive tasks: a search algorithm generates a large number of candidate conformations mimicking the complex existing in vivo between two proteins, and a scoring function is used to rank them in order to extract a native-like one. We have already shown that using Voronoi constructions and a well chosen set of parameters, an accurate scoring function could be designed and optimized. However to be able to perform large-scale in silico exploration of the interactome, a near-native solution has to be found in the ten best-ranked solutions. This cannot yet be guaranteed by any of the existing scoring functions. In this work, we introduce a new procedure for conformation ranking. We previously developed a set of scoring functions where learning was performed using a genetic algorithm. These functions were used to assign a rank to each possible conformation. We now have a refined rank using different classifiers (decision trees, rules and support vector machines) in a collaborative filtering scheme. The scoring function newly obtained is evaluated using 10 fold cross-validation, and compared to the functions obtained using either genetic algorithms or collaborative filtering taken separately. This new approach was successfully applied to the CAPRI scoring ensembles. We show that for 10 targets out of 12, we are able to find a near-native conformation in the 10 best ranked solutions. Moreover, for 6 of them, the near-native conformation selected is of high accuracy. Finally, we show that this function dramatically enriches the 100 best-ranking conformations in near-native structures.
Performance of turbo codes in Rayleigh fading channels with adaptive channel estimation (2002)

For turbo-coding systems in mobile fading environments, fading amplitudes must be provided to the turbo decoder in order to exhibit the full potential of turbo codes. We investigate the performance of turbo-coding systems with adaptive channel estimation in the Rayleigh flat-fading channels. Two system models are considered for simulations. In the first model, the channel estimation is performed prior to the turbo decoder. In the second model, the decision-directed approach for refined channel estimation is considered where the fading amplitudes are re-estimated with the aid of the hard-decided turbo-decoder outputs. The least mean square (LMS) algorithm and the general optimum block adaptive (GOBA) algorithm are used for the adaptive channel estimators in the two system models. Simulation results have shown that the GOBA channel estimator with the decision-directed approach provides much better estimates of the fading amplitudes, thereby significantly improving the bit error rate (BER) performance of the turbo-coding systems.
Classes of bandpass filters having an arbitrary wide stopband and design tables for one such class (2002)

Several filter classes that can be used to obtain a bandpass filter with an arbitrary stopband width are defined. These filters have the advantage that they are physically very small because the quarter-wave frequency is situated much higher than the center frequency. Design tables for relative bandwidths of 90 and 100% are given, and measured results for a stripline filter without chip capacitors are presented.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
LTNN: A Layerwise Tensorized Compression of Multilayer Neural Network (2018)

An efficient deep learning requires a memory-efficient construction of a neural network. This paper introduces a layerwise tensorized formulation of a multilayer neural network, called LTNN, such that the weight matrix can be significantly compressed during training. By reshaping the multilayer neural network weight matrix into a high-dimensional tensor with a low-rank approximation, significant network compression can be achieved with maintained accuracy. An according layerwise training is developed by a modified alternating least-squares method with backward propagation for fine-tuning only. LTNN can provide the state-of-the-art results on various benchmarks with significant compression. For MNIST benchmark, LTNN shows 64 × compression rate without accuracy drop. For Imagenet12 benchmark, our proposed LTNN achieves 35.84 × compression of the neural network with around 2% accuracy drop. We have also shown 1.615 × faster on inference speed than the existing works due to the smaller tensor core ranks.
The role of gut microbiota in immune homeostasis and autoimmunity (2012)

Keeping a delicate balance in the immune system by eliminating invading pathogens, while still maintaining self-tolerance to avoid autoimmunity, is critical for the body's health. The gut microbiota that resides in the gastrointestinal tract provides essential health benefits to its host, particularly by regulating immune homeostasis. Moreover, it has recently become obvious that alterations of these gut microbial communities can cause immune dysregulation, leading to autoimmune disorders. Here we review the advances in our understanding of how the gut microbiota regulates innate and adaptive immune homeostasis, which in turn can affect the development of not only intestinal but also systemic autoimmune diseases. Exploring the interaction of gut microbes and the host immune system will not only allow us to understand the pathogenesis of autoimmune diseases but will also provide us new foundations for the design of novel immuno- or microbe-based therapies.
Profanity in Media Associated With Attitudes and Behavior Regarding Profanity Use and Aggression (2011)

The main hypothesis was confirmed, and implications for the rating industry and research field are discussed.
Nuclear factor kappa B signaling in catabolic disorders (2002)

The nuclear factor kappa B family of inducible transcription factors regulates the expression of many genes. Nuclear factor kappa B has been implicated in autoimmune and inflammatory diseases, infection, cell survival, and cell transformation with subsequent promotion of cancer. In this review, we summarize features of nuclear factor kappa B regulation in several catabolic disorders, and describe its role in normal cellular function as well as provide an important link to the role of scaffold proteins, cellular receptors, and other cell signaling pathway kinases that converge on the nuclear factor kappa B signaling cascade. Subsequently, we focus on the role of nuclear factor kappa B in cell survival and oxidative stress. Finally, potential therapeutic strategies are discussed that may modify nuclear factor kappa B activity including endogenous antioxidant systems and the Fas/FasL system. However, challenges still remain in developing new therapeutic strategies that not only include identifying novel agents, but also by improving clinical endpoint definitions and by defining biological efficacy.
Effect of LIF on Expression of Matrix Metalloproteinases (MMPs) in Cultured Mouse Embryo (2002)

In order to investigate the mechanism of the essential role of leukemia inhibitory factor (LIF) in blastocyst implantation, blastocyst was incubated with LIF and its specific antibody. The effect of LIF on matrix metalloproteinases (MMPs) of pre implantation blastocyst was analysized by RT PCR and immuno bloting techniques. The results showed that gene expression and secretion of MMP9 were significantly induced by LIF treatment, after blocking by LIF antibody, those effects were decreased, and the decreasing tendency was weakened with the increase of the incubation time. However the effect of LIF on tissue inhibitor of metalloproteinase1(TIMP1) was not obviously. The results indicate that LIF may play its role by inducing the gene expression and increasing the secretion of MMP9 to facilitate blastocyst implantation.
Sugar-Starch Transformation in Peas, Relation between Changes in Glucose, Fructose, Galactose, Sucrose, and Stachyose, and the Formation of Starch in Peas (1961)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSugar-Starch Transformation in Peas, Relation between Changes in Glucose, Fructose, Galactose, Sucrose, and Stachyose, and the Formation of Starch in PeasR. S. Shallenberger and J. C. MoyerCite this: J. Agric. Food Chem. 1961, 9, 2, 137–140Publication Date (Print):March 1, 1961Publication History Published online1 May 2002Published inissue 1 March 1961https://pubs.acs.org/doi/10.1021/jf60114a014https://doi.org/10.1021/jf60114a014research-articleACS PublicationsRequest reuse permissionsArticle Views179Altmetric-Citations12LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Learning and aging related changes in intrinsic neuronal excitability (2010)

A goal of many laboratories that study aging is to find a key cellular change(s) that can be manipulated and restored to a young-like state, and thus, reverse the age-related cognitive deficits. We have chosen to focus our efforts on the alteration of intrinsic excitability (as reflected by the postburst afterhyperpolarization, AHP) during the learning process in hippocampal pyramidal neurons. We have consistently found that the postburst AHP is significantly reduced in hippocampal pyramidal neurons from young adults that have successfully learned a hippocampus-dependent task. In the context of aging, the baseline intrinsic excitability of hippocampal neurons is decreased and therefore cognitive learning is impaired. In aging animals that are able to learn, neuron changes in excitability similar to those seen in young neurons during learning occur. Our challenge, then, is to understand how and why excitability changes occur in neurons from aging brains and cause age-associated learning impairments. After understanding the changes, we should be able to formulate strategies for reversing them, thus making old neurons function more as they did when they were young. Such a reversal should rescue the age-related cognitive deficits.
A New Approach to the Synthesis of 4-Thio-1,2-Dideoxyribose (1995)

A novel approach to the synthesis of racemic 4-thio-1,2-deoxyribose (1) is described. Thus, commercially available γ-thiobutyrolactone is converted to the thiolenol triflate (3) and then to the key 5-(hydroxymethyl)-2,3-dihydrothiophene (2). Hydroboration followed by oxidative work up gives the desired product (1) in four steps.
Adaptive Orthogonal Frequency Division Multiplexing Schemes (1998)

This paper investigates the upper-bound performance of subband-adaptive Orthogonal Frequency Division Multiplexing (OFDM) transmission in a time-dispersive channel and the feasibility of blind modulation scheme detection algorithms not requiring modulation scheme signalling information. Simulation results for a modem employing two and four modulation modes are presented using blind modulation mode detection.
Comparison of ELISA and dot-hybridization for detection of alfalfa mosaic virus in alfalfa pollen (1988)

(1988). Comparison of ELISA and dot-hybridization for detection of alfalfa mosaic virus in alfalfa pollen. Canadian Journal of Plant Pathology: Vol. 10, No. 2, pp. 116-122.
Etching of Abraded Germanium Surfaces with CP-4 Reagent (1962)

The dissolution of the damaged layer has been investigated by a metallographic taper‐sectioning technique and by direct microscopical examination of the etched surfaces. It is shown that the reagent penetrated the damage cracks in abraded surfaces opening them into deep crevices. At the same time, the surface begins to be smoothed out, a characteristic cellular pattern being produced. A completely flat surface is not achieved until well after the damaged layer is removed. A critical comparison of certain methods of estimating the depth of the damaged layer is made in the light of these observations. It is concluded that metallographic methods are the most reliable.
Asset cycle management-a total approach to product design for the environment (2002)

The recycle process that is being employed by Xerox Corporation is described. The emphasis of the process is total asset recovery management. At Xerox Corporation, the commitment is to design products, modules and parts from the start of design to the remanufactured immediately following launch or for the materials to be totally recycled at the end-of-life of the product. The goal of the Asset Recovery Management Program is to achieve 0% material being dispositioned to the landfill in order to minimize the impact on the environment. The authors describe the implementation of this program by outlining the principles used throughout the product development cycle from the concept phase to design, production, launch, remanufacture, and final recycle. Some of the tools which enable total asset management are covered, including design guidelines, specifications, quality, reliability requirements, product conversion, life cycle analysis, and end-of-life disposal or material recycling.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
The role of neurotrophins in the developing nervous system (1994)

Neurotrophins were originally identified by their ability to promote the survival of developing neurons. However, recent work on these proteins indicates that they may also influence the proliferation and differentiation of neuron progenitor cells and regulate several differentiated traits of neurons throughout life. Moreover, the effects of neurotrophins on survival have turned out to be more complex than originally thought. Some neurons switch their survival requirements from one set of neurotrophins to another during development, and several neurotrophins may be involved in regulating the survival of a population of neurons at any one time. Much of our understanding of the developmental physiology of neurotrophins has come from studying neurons of the peripheral nervous system. Because these neurons and their progenitors are segregated into anatomically discrete sites, it has been possible to obtain these cells for in vitro experimental studies from the earliest stage of their development. The recent generation of mice having null mutations in the neurotrophin and neurotrophin receptor genes has opened up an unparalleled opportunity to assess the physiological relevance of the wealth of data obtained from these in vitro studies. Here I provide a chronological account of the effects of members of the NGF family of neurotrophins on cells of the neural lineage with special reference to the peripheral nervous system.
Work measurement – the basic principles revisited (1995)

In these days of total quality management, business process re‐engineering, etc. it is easy to forget tried and tested approaches to productivity and performance measurement and improvement. Work measurement, for example, has been around for many years but still can be extremely effective in informing us of the working times, and delays, inherent in different ways of carrying out work.
Move it or lose it: axis specification in Xenopus (2004)

A long-standing question in developmental biology is how amphibians establish a dorsoventral axis. The prevailing view has been that cortical rotation is used to move a dorsalizing activity from the bottom of the egg towards the future dorsal side. We review recent evidence that kinesin-dependent movement of particles containing components of the Wnt intracellular pathway contributes to the formation of the dorsal organizer, and suggest that cortical rotation functions to align and orient microtubules, thereby establishing the direction of particle transport. We propose a new model in which active particle transport and cortical rotation cooperate to generate a robust movement of dorsal determinants towards the future dorsal side of the embryo.
Overview and extensions of a system for routing directed graphs on SIMD architectures (2003)

A method is given for parallelizing the problems of directed graphs on a single-instruction multiple-data (SIMD) machine model that uses only nearest-neighbor connections for communication and has no facility for local indirect addressing. Each vertex of the graph is assigned to a processor in the machine. Rules for labeling are introduced that support the use of a simple algorithm for movement of data along the edges of the graph. Additional algorithms are defined for addition and deletion of edges. Modifying or adding a new edge takes the same time as parallel traversal. This combination of architecture and algorithm defines a system that is relatively simple to build and can do fast graph processing. All edges can be traversed in parallel in time O(T), where T is empirically proportional to the average path length in the embedding times the average degree of the graph. An extension to the above method is presented which allows for enhanced performance by allowing some broadcasting capabilities.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>