gebhart/patrepeval huggingface dataset:
Poly(ADP-Ribose) Polymerase Inhibition Improves Corneal Epithelial Innervation and Wound Healing in Diabetic Rats (2015)

Diabetic corneas showed loss of epithelial innervation, resulting in delayed epithelial healing and decreased corneal sensitivity. Inhibition of poly(ADP-ribose) polymerase (PARP) with 1,5-isoquinolinediol alleviated these diabetes-induced alterations in the corneal epithelium in the diabetic rats.
Distributed Genetic Algorithm for Optimization of Wind Farm Annual Profits (2007)

In this paper, a distributed genetic algorithm is adopted to search the optimal number and locations of wind turbines in large wind farms. The objective of this optimal process is to find a solution that maximizes the annual profit obtained from a wind farm. It is well known that traditional genetic algorithms are time consuming and the quality of final solution is not very well. For improving the performance of finding the optimal solution in large search space, the distributed genetic algorithm provides a powerful strategy for searching the global optimal by dividing large population into multiple small subpopulations that occasionally exchange some individuals. Test results show that the distributed genetic algorithm well demonstrates its effectiveness on solution quality and execution time.
The Action of Sodium on Di-s-butylmercury (1951)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe Action of Sodium on Di-s-butylmercuryJohn F. Lane and Stephen E. UlrichCite this: J. Am. Chem. Soc. 1951, 73, 11, 5470–5471Publication Date (Print):November 1, 1951Publication History Published online1 May 2002Published inissue 1 November 1951https://pubs.acs.org/doi/10.1021/ja01155a537https://doi.org/10.1021/ja01155a537research-articleACS PublicationsRequest reuse permissionsArticle Views22Altmetric-Citations4LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Predictive Value of Dialysate Cell Counts in Peritonitis Complicating Peritoneal Dialysis (2006)

Early prediction of outcomes has major potential implications regarding the management of dialysis-related peritonitis. The outcomes of 565 consecutive episodes of peritonitis complicating peritoneal dialysis between August 2001 and July 2005 were evaluated in relation to the dialysate cell counts. Discriminatory power, based on the area under the receiver-operating characteristic (ROC) curves, of the cell counts was assessed. The findings then were validated externally in a cohort of 217 peritonitis episodes from another dialysis unit. During the study period, 565 episodes of peritonitis were included for analysis, 465 of which had treatment success defined as complete resolution of peritonitis without the need for Tenckhoff catheter removal. Of the remaining 100 episodes (treatment failure), 70 required Tenckhoff catheter removal and 30 had peritonitis-related death. The peritoneal dialysate total white blood cell count on day 3 of peritonitis predicted treatment failure independent of standard risk factors, and it had a higher area under the ROC curve than the dialysate white cell count on day 1 (0.80 versus 0.58; P < 0.0001). Using a peritoneal dialysate white count cut point > or = 1090/mm3 on day 3, the sensitivity was 75% and the specificity was 74% for the prediction of treatment failure (defined as catheter loss or peritonitis-related death). In multiple logistic regression analyses, peritoneal dialysate white count > or = 1090/mm3 on day 3 was an independent prognostic marker for treatment failure after adjustment for conventional risk factors (hazard ratio 9.03; 95% confidence interval 4.40 to 18.6; P < 0.0001). Number of years on peritoneal dialysis; diabetes; gram-negative organisms; and Pseudomonas, fungal, or Mycobacterium species were other independent risk factors that were predictive of treatment failure. Findings from an independent validation set of peritonitis (217 episodes after exclusion of Mycobacterium and fungal causes) also favored the peritoneal dialysate white count on day 3, as compared with day 1 and day 2, to predict treatment failure. Area under the ROC curve for the white counts on day 3 was 0.98 (95% confidence interval 0.95 to 0.99) in the validation set. This study demonstrated and cross-validated the superiority of peritoneal dialysate white cell count on day 3 to predict outcomes of dialysis-related peritonitis. These results call attention to the value of validating prognostic factors of peritonitis complicating peritoneal dialysis.
Content-Aware Point of Interest Recommendation on Location-Based Social Networks (2015)

The rapid urban expansion has greatly extended the physical boundary of users' living area and developed a large number of POIs (points of interest). POI recommendation is a task that facilitates users' urban exploration and helps them filter uninteresting POIs for decision making. While existing work of POI recommendation on location-based social networks (LBSNs) discovers the spatial, temporal, and social patterns of user check-in behavior, the use of content information has not been systematically studied. The various types of content information available on LBSNs could be related to different aspects of a user's check-in action, providing a unique opportunity for POI recommendation. In this work, we study the content information on LBSNs w.r.t. POI properties, user interests, and sentiment indications. We model the three types of information under a unified POI recommendation framework with the consideration of their relationship to check-in actions. The experimental results exhibit the significance of content information in explaining user behavior, and demonstrate its power to improve POI recommendation performance on LBSNs.
GSIFT: geometric scale invariant feature transform for terrain data (2006)

In this work, we introduce GSIFT (Geometric Scale Invariant Terrain Feature Transform), geometric descriptors that are invariant to translation, rotation, and scaling. SIFT (Scale Invariant Feature Transform) descriptors have been found to be very successful in a variety of computer vision tasks. GSIFT expands SIFT by using the novel technique of binding features at different scales to associate priorities/importance to features based on its scale and persistence among different scales. As a first step to obtain scale invariance, we create a multi-scale pyramid for detecting important features such as maxima, minima, and saddle points for 1D and 2D height fields. We use relative height histograms as GSIFT with support regions determined by the priority of the feature. We use symmetric chi-square as the similarity measure to compare geometric features. Experiments with GSIFT and SIFT (on images constructed from height fields) on both synthetic and real height field data sets show that GSIFT provide comparable and in some cases, better results for data registration. GSIFT has the added advantage that it can be used by scientists in compressing and registering (or non-registering) height data, where it is important for them to understand which features to keep/discard or why the registration is good/poor, when the data is obtained at different scales from independent sources.
An Efficient TCP Mechanism for Mobile IP Handoffs (2002)

When using TCP over a mobile network, TCP responds to a handoff by invoking a congestion control algorithm, thereby resulting in a degraded end-to-end performance in a mobile network. In this paper, two schemes are proposed, TCP-MD and TCP-R. TCP-MD can detect the movement of s mobile host early on, whereas TCP-R can force the source to freeze data transmission during registration. The proposed schemes maintain end-to-end TCP semantics, making it possible to fully interoperate with the existing infrastructure. Only a small change is required in the mobile host, plus the implementation is simple because some Mobile IP messages are used to notify the handoff, eliminating the need for any additional messages. Simulations confirmed that the proposed schemes give an excellent performance under various environments.
Effect of acupuncture on cardiopulmonary function. (1996)

Our results indicate that acupuncture can decrease the resting heart rate and carbon dioxide production, thus lowering the metabolic rate.
Adenocarcinomas in the cervicovaginal papanicolaou smear: Analysis of a 12‐year experience (1991)

We attempted to reassess the significance of cervicovaginal Papanicolaou smear(s) in identifying adenocarcinoma (AC) by comparing Papanicolaou smears with histopathology in a pool of 188 patients. The first part of study dealt with 95 patients, seen over a 12-yr period (1975-1986), who had tissue diagnosis of cervical or endometrial AC, all with prior papanicolaou smears available. Of the 95 patients, Papanicolaou smears were positive and/or inconclusive for uterine AC in 37 (38.9%) and falsely negative in 58 (61.1%) patients. Of the latter, six were either positive and/or inconclusive for squamous carcinoma and moderate to severe dysplasia; thus, the effective detection rate (sensitivity) for malignancy and related condition of Papanicolaou smears was 45.3% (43 of 95). The second part of the study concerned the analysis of 130 patients with 148 Papanicolaou smear in whom cytologic diagnosis positive and/or inconclusive for AC was made during the same study period. Tissue diagnoses were available in 107 of these as follows: AC and glandular hyperplasia in 66 patients (61.7% predictive value), with 11 (10.3%) from extrauterine sources; squamous carcinoma in 12 and moderate to severe dysplasia in 5, totalling 17 patients (15.9%); miscellaneous conditions (polyps, radiation change, and glandular atrophy) in 11 patients (10.3%); and no pathologic change in 13 patients (12.1%). The effective predictive value of positive and/or inconclusive Papanicolaou smears for all malignancy and related states is 77.6%.
Liquid Water Removal from a Polymer Electrolyte Fuel Cell (2006)

Liquid water transport and removal from the gas diffusion layer (GDL) and gas channel of a polymer electrolyte fuel cell (PEFC) are studied experimentally and theoretically. In situ observations of the liquid water distribution on the GDL surface and inside the gas channel were made in an operating transparent PEFC. Liquid droplet formation and emergence from the GDL surface are characterized and two modes of liquid water removal from the GDL surface identified: one through droplet detachment by the shear force of the core gas flow followed by a mist flow in the gas channel, and the other by capillary wicking onto the more hydrophilic channel walls followed by the annular film flow and/or liquid slug flow in the channel. In the former regime, typical of high gas flow rates, the droplet detachment diameter is correlated well with the mean gas velocity in the channel. In the latter regime characteristic of low gas flow rates, liquid spreading over hydrophilic channel surfaces and drainage via corner flow were observed and analyzed. A theory is developed to determine what operating parameters and channel surface contact angles lead to sufficient liquid drainage from the fuel cell via corner flow. Under these conditions, the fuel cell could operate stably under a low flow rate (or stoichiometry) with only a minimum pressure drop required to drive the oxidizer flow. However, when the corner flow is insufficient to remove liquid water from the gas channel, it was observed that the annular film flow occurs, often followed by film instability and channel clogging. Channel clogging shuts down an entire channel and hence reduces the cell's active area and overall performance.
Robust Stoichiometry of FliW-CsrA Governs Flagellin Homeostasis and Cytoplasmic Organization in Bacillus subtilis (2019)

Flagellin (Hag) is one of the most abundant proteins in <i>Bacillus subtilis</i> Here we show that each flagellar filament is assembled from ∼12,000 Hag monomers and that there is a cytoplasmic pool of Hag that is restricted to 5% of the total. Hag is thought to be restricted at the level of translation by a partner-switching mechanism involving FliW and the homodimeric RNA-binding protein CsrA (CsrA<sup>dimer</sup>). We further show that the mechanism of translation inhibition is hypersensitive due to a 1:1 ratio of Hag to FliW, a 1:1 inhibitory ratio of FliW to CsrA<sup>dimer</sup>, and a nearly 1:1 ratio of CsrA<sup>dimer</sup> to <i>hag</i> transcripts. Equimolarity of all components couples single-molecule detection of Hag export to compensatory translation and causes cytoplasmic Hag concentrations to oscillate around the level of FliW. We found that stoichiometry is ensured by genetic architecture, translational coupling, and the ability of CsrA<sup>dimer</sup> to restrict <i>hag</i> transcript accumulation. We further show that homeostasis prevents Hag hyperaccumulation that would otherwise cause severe defects in intracellular architecture, perhaps due to increased molecular crowding. We note that FliW-CsrA-mediated structural homeostasis has similarities to that seen with some toxin-antitoxin systems.<b>IMPORTANCE</b> The intracellular concentration of flagellar filament protein Hag is restricted by the Hag-FliW-CsrA system in <i>B. subtilis</i> Here we show that the Hag-FliW-CsrA<sup>dimer</sup> system functions at nearly 1:1:1 stoichiometry and that the system is both robust with respect to perturbation and hypersensitive to the Hag intracellular concentration. Moreover, restriction of cytoplasmic Hag levels is important for maintaining proper intracellular architecture, as artificial Hag hyperaccumulation led to generalized spatial defects and a high frequency of minicell production. The Hag-FliW-CsrA system is conserved in the deeper branches of bacterial phylogeny, and we note that the Hag-FliW-CsrA "homeostasis module" resembles a toxin-antitoxin system where, by analogy, CsrA is the "toxin," FliW is the "antitoxin," and Hag is the target.
Affinity Labeling of Anti-Lactose Antibodies with Bromoacetylaminolac Dye in Dark (1975)

Affinity labeling of rabbit IgG anti-lactose antibodies of restricted heterogeneity by bromacetylaminolac dye was carried out in dark and the label on the isolated chains determined by SDS gel electrophoresis. The pattern of labeling was compared with that obtained when the reaction was carried out in light using the same reagent. Differences were observed in the mode of labeling of chains. Possible use of mapping the active site of the antibody by the same labeling reagent which can exist in two geometrical forms under dark and light conditions is discussed.
SYNTHESIS OF SILICONE MAGNETIC FLUIDS FOR USE IN EYE SURGERY (2002)

Stable suspensions of superparamagnetic cobalt nanoparticles have been prepared in poly(dimethysiloxane) (PDMS) carrier fluids in the presence of poly[dimethylsiloxane-b-(3-cyanopropyl)methylsiloxane-b-dimethylsiloxane] (PDMS-PCPMS-PDMS) triblock copolymers as steric stabilizers. A series of the polysiloxane triblock copolymers with systematically varied molecular weights were prepared via anionic polymerization using LiOH as an initiator. These copolymers formed micelles in toluene or poly(dimethylsiloxane) (PDMS) carrier fluids and served as "nanoreactors" for thermal decomposition of the CO₂(CO)8 precursor. The nitrile groups on the PCPMS central blocks are thought to coordinate onto the particle surface, while the PDMS endblocks protrude into the reaction medium to provide steric stability. The particle size can be controlled by adjusting the cobalt to copolymer ratio. Ordered self-assemblies of these cobalt nanoparticles are observed when the dispersions are cast from toluene. Electron diffraction spectroscopy reveals that the cobalt nanoparticles have fcc crystal structures. TEM shows non-aggregated cobalt nanoparticles with narrow size distributions, which are evenly surrounded with copolymer sheaths. However, some degree of surface oxidation was observed over time, resulting in a decrease in magnetic susceptibility. Novel poly[dimethylsiloxane-b-methyltriethoxysilylsiloxane-b-(3-cyanopropyl) methylsiloxane-b-methyltriethoxysilylsiloxane-b-dimethylsiloxane] (PDMS-PMTEOS-PCPMS-PMTEOS-PDMS) pentablock terpolymers were prepared. These terpolymers could fill the dual role both as steric stabilizers for preparing stable cobalt nanoparticle dispersions and precursors for the particle coating process. Silica films coated on the particles surfaces were employed to prevent the surface oxidation of the nanoparticles. Specific saturation magnetic measurement indicates that coating the nanoparticles with silica thin films can effectively inhibit the oxidation process.
<i>Journal of Diabetes</i> News (2009)

Look, periodicals that bring together news and insights in these areas. The Journal of Diabetes will include this News feature, in which Close and Tjota review new developments relevant to researchers and clinicians.
Global consistency checking of distributed models with TReMer+ (2008)

We present TReMer+, a tool for consistency checking of distributed models (i.e., models developed by distributed teams).TReMer+ works by first constructing a merged model before checking consistency.This enables a flexible way of verifying global consistency properties that is not possible with other existing tools.
Link level performance results for a WCDMA random access scheme with preamble power ramping and fast acquisition indication (2003)

Advanced packet-access based services play a key role in third-generation mobile communication systems. Thus, flexible and power-efficient random and packet access schemes with low access delay are identified as an important feature. This paper describes the random access proposal adopted for WCDMA, the third-generation system jointly specified by several standardization bodies within the 3rd-Generation Partnership Project (3GPP). Link level performance results for this method with preamble power ramping and fast acquisition indication are presented.
Production of Vitamin C by Fermentation (1953)

In the previous reports, it was ascertained that Pseudomonas fluorescens sp. isolated by the author produced a large amount of 2-keto-L-gulonic acid from Ca-D-idonate (containing a half quantity of Ca-D-gluconate) and that the separation of 2-keto-L gulonic acid from 2-keto-D-gluconic acid which produced simultaneously from Ca-D-gluconate was achieved by using the difference of the solubility of their Na-salt in methanol. Now, the author intended about the synthesis of vitamin C from Na-2-keto-L-gulonate thus obtained. The summary of the results is as follows: 1. Free 2-keto-L-gulonic acid crystal was obtained with ca. 80% yield from its Na-salt. 2. The optimum temperature for the methyl esterification of 2-keto-L-gulonic acid was 48_??_50° in 30 minute reaction and the yield of methyl ester crystal was 83.01 by the REICHSTEIN's method. Then the methyl ester was converted to vitamin C by heating with weak alkalic solution and after removingmetallic cations with the ion-exchange resin. The yield.of the vitamin C was about 90%. 3. Vitamin C was also prepared directly from free 2-keto-L-gulonic acid by the process of author's modification of the REICHSTEIN's method, viz using benzol instead of chloroform and butanol instead of ethanol as HCl-gas absorbing agent. The yield of vitamin C crystal was ca. 77% (93% purity). (The original REICHSTEIN's method gave 801 (95;o purity) yield from diacetone-2-keto-L-gulonic acid.)
Endoscopic Grading of Reflux Oesophagitis: What Observations Correlate with Gastro-Oesophageal Reflux? (1997)

Red spots and streaks, even without whitish exudate, are significantly related to pathologic gastro-oesophageal reflux. Whitish exudate is related to more severe reflux, and broad lesions to a longer mean duration of the episodes. The presence of whitish exudate in lesions and the width of the lesions are important observations to use in the classification of reflux oesophagitis.
An R*-Tree Based Semi-Dynamic Clustering Method for the Efficient Processing of Spatial Join in a Shared-Nothing Parallel Database System (2006)

The growing importance of geospatial databases has made it essential to perform complex spatial queries efficiently. To achieve acceptable performance levels, database systems have been increasingly required to make use of parallelism. The spatial join is a computationally expensive operator. Efficient implementation of the join operator is, thus, desirable. The work presented in this document attempts to improve the performance of spatial join queries by distributing the data set across several nodes of a cluster and executing queries across these nodes in parallel. This document discusses a new parallel algorithm that implements the spatial join in an efficient manner. This algorithm is compared to an existing parallel spatial-join algorithm, the clone join. Both algorithms have been implemented on a Beowulf cluster and compared using real datasets. An extensive experimental analysis reveals that the proposed algorithm exhibits superior performance both in declustering time as well as in the execution time of the join query.
Zoonoses in the Bedroom (2011)

In most industrialized countries, pets are becoming an integral part of households, sharing human lifestyles, bedrooms, and beds. The estimated percentage of pet owners who allow dogs and cats on their beds is 14%-62%. However, public health risks, including increased emergence of zoonoses, may be associated with such practices.