gebhart/patrepeval huggingface dataset:
Regulation of Serratia marcescens ompF and ompC porin genes in response to osmotic stress, salicylate, temperature and pH (2006)

Serratia marcescens is a Gram-negative enterobacterium that has become an important opportunistic pathogen, largely due to its high degree of natural antibiotic resistance. One factor contributing to this natural antibiotic resistance is reduced outer membrane permeability, which is controlled in part by OmpC and OmpF porin proteins. OmpF expression is regulated by micF, an RNA transcript encoded upstream of the ompC gene, which hybridizes with the ompF transcript to inhibit its translation. Regulation of S. marcescens porin gene expression, as well as that of micF, was investigated using beta-galactosidase reporter gene fusions in response to 5, 8 and 10 % sucrose, 1, 5 and 8 mM salicylate, and different pH and temperature values. beta-Galactosidase activity assays revealed that a lower growth temperature (28 degrees C), a more basic pH (pH 8), and an absence of sucrose and salicylate induce the transcription of the ompF gene, whereas the induction of ompC is stimulated at a higher growth temperature (42 degrees C), acidic pH (pH 6), and maximum concentrations of sucrose (10 %) and salicylate (8 mM). In addition, when multiple conditions were tested, temperature had the predominant effect, followed by pH. In this study, it was found that the MicF regulatory mechanism does not play a role in the osmoregulation of the ompF and ompC genes, whereas MicF does repress OmpF expression in the presence of salicylate and high growth temperature, and under low pH conditions.
Statistical analysis of heart rate and heart rate variability monitoring through the use of smart phone cameras (2012)

Video recordings of finger tips made using a smartphone camera contain a pulsatile component caused by the cardiac pulse equivalent to that present in a photoplethysmographic signal. By performing peak detection on the pulsatile signal it is possible to extract a continuous heart rate signal. We performed direct comparisons between 5-lead electrocardiogram based heart rate variability measurements and those obtained from an iPhone 4s and Motorola Droid derived pulsatile signal to determine the accuracy of heart rate variability measurements obtained from the smart phones. Monitoring was performed in the supine and tilt positions for independent iPhone 4s (2 min recordings, n=9) and Droid (5 min recordings, n=13) experiments, and the following heart rate and heart rate variability parameters were estimated: heart rate, low frequency power, high frequency power, ratio of low to high frequency power, standard deviation of the RR intervals, and root mean square of successive RR-differences. Results demonstrate that accurate heart rate variability parameters can be obtained from smart phone based measurements.
1,2-Bis(diethylamino)cyclopropenium Tetraphenylborate (2016)

1,2-Bis(diethylamino)cyclopropenium Tetraphenylborate [1559066-97-5] HC3(N(CH2CH3)2)2+ B(C6H5)4− (MW 500.54) InChI = 1S/C24H20B.C11H21N2/c1-5-13-21(14-6-1)25(22-15-7-2-8-16-22,23-17-9-3-10-18-23)24-19-11-4-12-20-24;1-5-12(6-2)10-9-11(10)13(7-3)8-4/h1-20H;9H,5-8H2,1-4H3/q-1;+1 InChIKey = HJSXWRRQSBRWCA-UHFFFAOYSA-N Physical Data: crystalline white solid, mp 132–133 °C. Solubility: soluble in CH2Cl2, CHCl3, acetone, and MeOH (hot). Analysis of Reagent Purity: 1H NMR (500 MHz, CHCl3) δ 7.51 (br s, 8H), 7.03 (t, J = 7.1 Hz, 8H), 6.86 (t, J = 7.1 Hz, 4H), 4.46 (br s, 1H), 3.20 (q, J = 7.5 Hz, 4H), 3.10 (q, J = 7.5 Hz, 4H), 1.21 (t, J = 7.5 Hz, 6H), 1.11 (t, J = 7.5 Hz, 6H); 13C NMR (125 MHz, CHCl3) δ 164.4 (q, 1JCB = 49 Hz), 136.2, 135.4, 125.9 (q, 2JCB = 2.8 Hz), 122.0, 98.2, 48.1, 46.9, 14.2, 12.9; FTIR (KBr thin film) νmax (cm−1): 3108, 3053, 2984, 1895, 1589; HRMS (ESI+) m/z calculated for C11H21N2+ [M+]: 181.1699; found: 181.1703; Elemental Analysis calculated: %C: 83.99, %H: 8.26, %N: 5.60; found: %C: 83.88, %H: 7.99, %N: 5.50. Handling, Storage, and Precautions: material can be stored and handled under ambient conditions without inert atmosphere or special precautions.
The New Public Management is not that bad after all (2014)

This article reviews the New Public Management (NPM) literature in Central and Eastern Europe, looking particularly at reforms in Estonia, Hungary and Romania. It finds that research that assessed changes in internal processes and activities within the public sector by far outnumber research that assessed changes in outputs and outcomes. Overall more studies have found positive than negative effects – especially in terms of processes and activities – but less so for outputs and outcomes. Significant challenges in assessing impacts make sweeping claims about whether NPM “works” difficult to support with solid evidence. The paper shows that NPM policy is still considered as an option for public sector modernization in Central and Eastern Europe and suggests that a number of NPM components, if not the model as a whole, are likely to continue to exert influence on the public sector in the future.
New Crown-Shaped Polyoxovanadium(V) Cluster Cation with a μ<sub>6</sub>-Sulfato Anion and Zwitterionic μ-(β-Alanine):  Crystal Structure of [V<sub>6</sub>O<sub>12</sub>(OH)<sub>3</sub>(O<sub>2</sub>CCH<sub>2</sub>CH<sub>2</sub>NH<sub>3</sub>)<sub>3</sub>(SO<sub>4</sub>)][Na][SO<sub>4</sub>]·13H<sub>2</sub>O (2001)

Treatment of vanadium(V) oxide with an ethanol-concentrated sulfuric acid mixture, followed by the addition of an equimolar amount of beta-alanine and sodium hydroxide, and finally raising the pH to 3.9 with sodium carbonate solution, under continuous heating in a water bath and in the presence of air, leads to the polyionic sodium cyclo-[mu(6)-(sulfato-O,O',O'')tris[mu-(beta-alanine-O,O')-mu-oxo]tris(mu-hydroxo-mu-oxo)hexa[oxovanadium(V)]] sulfate tridecahydrate which crystallizes in the monoclinic P2(1)/n space group [a = 9.5192(4), b = 20.1185(9), c = 22.6174(9) A, beta = 97.011(1) degrees; Z = 4]. The crown-shaped polyoxovanadium(V) cluster cation, with carboxylate-bridging amino acid ligands, has an Anderson structure with two unique capping sulfato ligands. Its structural analysis, together with IR, UV-vis, and preliminary data on its solution properties, is presented.
One‐Pot Synthesis of an Acid‐Labile Amphiphilic Triblock Copolymer and its pH‐Responsive Vesicular Assembly (2013)

Ein amphiphiles Triblockcopolymer, das durch einen säurelabilen β-Thiopropionat-Linker segmentiert wird, wurde aus einem Dithiol, einem Diacrylat und einem hydrophilen Polymer mit endständigem Acrylat in zwei Stufen in einem Gefäß synthetisiert. Es assemblierte spontan zu Vesikeln, die unter schwach sauren Bedingungen zerfallen und dabei nichtkovalent eingeschlossene Gastmoleküle freisetzen.
Topical Review: Long-Term Developmental Outcome of Asphyxiated Term Neonates (2001)

Asphyxia remains one of the main causes of later disability in term infants. Despite many publications identifying possible predictors of outcome in this population of interest, little is known of the long-term developmental outcome of asphyxiated term neonates. Observational studies have largely focused on short-term outcomes, with an emphasis on significant neurologic sequelae and intellectual impairments. This article reviews the literature that has described the developmental outcome of asphyxiated term newborns. As part of this review, we have also highlighted the evolution of the definition of asphyxia and delineated appropriate markers that should be used in future research on this population.
Analysis and optimization of gate leakage current of power gating circuits (2006)

Power gating is widely accepted as an efficient way to suppress subthreshold leakage current. Yet, it suffers from gate leakage current, which grows very fast with scaling down of gate oxide. We try to understand the sources of leakage current in power gating circuits and show that input MOSFETs play a crucial role in determining total gate leakage current. It is also shown that the choice of a current switch in terms of polarity, threshold voltage, and size has a significant impact on total leakage current. From the observation of the importance of input MOSFETs, we propose the power optimization of power gating circuits through input control.
Tune spectra in the Tevatron collider (2003)

A variety of transverse and longitudinal tune studies have been made in the Tevatron with both single and colliding beams. In addition to measurements of such typical quantities as tunes, chromaticity, observations of beam-beam tune shifts and coherent beam-beam normal mode oscillations have also been made. A number of measurements are reported where the beam response to stimulation is studied. The data were acquired when the Tevatron was either at 150 GeV or at the colliding beam physics energy of 900 GeV. In both cases either there were only protons circulating or there were six proton bunches colliding with six antiproton bunches.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
A New MPLS-Based Forwarding Paradigm for Multi-Radio Wireless Mesh Networks (2013)

Routing in multi-radio wireless mesh networks is a very challenging problem. In this paper, we propose a forwarding paradigm based on MPLS (Multi Protocol Label Switching) which makes use of a novel mechanism, denoted as MPLS splitting policy. Such mechanism allows to configure multiple next hops at an intermediate node, so that the incoming traffic is partitioned among the next hops according to predefined coefficients named split ratios. The MPLS splitting policy has been designed to allow for load balancing and fast local restoration. With such a mechanism, it is crucial to properly determine the set of split ratios, as they determine how the traffic is routed across the network. We present an approach to compute a set of split ratios that guarantee high performance under different traffic loads. To this end, we adopt the hose traffic model, according to which we only have knowledge of the maximum amount of traffic entering or leaving the network at each edge node. A thorough simulation study is conducted to show that our approach outperforms other routing protocols in terms of throughput and robustness against traffic load variations and single node failures.
Getting the Word Out (2002)

ABSTRACT This report assesses the available evidence on a community-wide pregnancy prevention campaign for pre-teens. In January 1997 a five-year media and educational campaign to combat pregnancy among pre-teens was launched in metropolitan Atlanta, combining an educational campaign in the media market with the distribution of educational materials in public school systems and youth-serving community organizations in two urban counties. The nonexperimental evaluation of the campaign draws on feedback from multiple perspectives-teachers who requested the campaign materials, the general population of adults and parents, and youth in the metro area. In addition, preliminary data on birth rates are presented.
Emergency departments I: using simulation in the architectural concept phase of an emergency department design (2003)

This paper describes an emergency care center simulation (ECC) project at Sarasota Memorial Hospital in Sarasota, Florida. The objective was to project bed requirements for an emergency care center expansion. The project team also analyzed the impact on downstream departments that are an integral part of the ECC. The simulation model was developed at a macro level and targeted the capacity requirements based on length of stay for each of the patient areas affected by the expansion. This macro-level model, used for the architectural concept phase, was designed to allow for enhancement into a micro-level model to analyze the detailed processes of the ECC once the basic concepts of layout, number of rooms and beds, and hours of operations were established.
Neurochemical imaging of Alzheimer's disease and other degenerative dementias. (1998)

A wide variety of neurochemical and functional imaging approaches have been applied to the study of progressive dementias, particularly Alzheimer's disease (AD) and related disorders. Despite considerable progress in the past decade, the cause(s) of most cases of AD remain undetermined and preventive or protective therapies are lacking. Specifically-designed imaging procedures have permitted the testing of pathophysiological hypotheses of the etiology and progression of AD, and have yielded important insights in several areas including the potential roles of cerebral cortical cholinergic lesions, cellular inflammation, and losses of cortical synapses. From the perspective of clinical diagnosis, PET glucose metabolism imaging with use of [18F]2-fluorodeoxyglucose (FDG) is the most sensitive and specific imaging modality yet identified. The overall performance of PET FDG is favorable for routine clinical evaluation of suspected AD, and will likely gain increasing utilization in the near future. Assessments of glucose metabolism and other, specific aspects of neurochemistry in AD will provide direct measures of therapeutic drug actions and may permit distinction of symptomatic versus disease-modifying therapies as they are developed and introduced in clinical trials.
A closed loop automated seating system. (1993)

This technical report presents the recent progress in the design and construction of a closed loop automated seating system. Preliminary test results are reported. The system is designed to measure seating surface forces and control the seating surface geometry of a seated human. It uses force information as feedback to determine custom seating contours which produce desired seating characteristics. Ultimately, the system is intended to be used for research studies with patients. The system consists of an electronically actuated, force-sensing seating surface which is controlled by a computer. Stepper motors are used to move force sensing probes up or down until the desired seating surface characteristic is attained. Preliminary test results are presented and analyzed. A force-equalizing control algorithm has been written and found to produce relatively uniform force distributions for soft, hemispherical loads of various weights.
Über Koordinationsverbindungen des Cadmiumdimethyls mit Äthern und tertiären Aminen (1964)

Abstract Cadmiumdimethyl bindet mit 1,4‐Dioxan und N,N,N′,N′,‐Tetraäthyläthylendiamin, 2,2′,‐Dipyridyl und 1,10‐Phenanthrolin kristalline Chelatverbindungen mit einer Ligandenmolekel pro Molekel Cadmiumdimethyl. Die Luftempfindlichkeit dieser Verbindungen ist wesentlich geringer als die des reinen Cadmiumdimethyls. Stärkere einwertige Liganden wie Tetrahydrofuran und Pyridin neigen zur Bildung von flüssigen 1:1‐Addukten. Diese Komplexverbindungen spalten sich beim Erwärmen weitgehend in ihre Komponenten und lassen sich daher nur schwer in stöchiometrischer Zusammensetzung erhalten.
Evaluation of Ramp Test Using Human Perception (2012)

The objectives of this study were to compare the results of HSL (Health and Safety Laboratory) ramp test with perceived sense of slip onto the several different floor surfaces under contaminated conditions. There are a variety of approaches from biomechanical measurements to psychophysical test and human perception. However, controversies over these approaches still remain. Some widely accepted methods need to be improved. AHP (Analytic Hierarchy Process) was used to evaluate the perception of slipperiness of seven different floor surfaces under the contaminated condition with glycerol solution. Twelve subjects worn same footwear and walked with self-selected step and cadence along the test floors. The angle of inclination obtained for water wet condition using 5 l/min with HSL ramp test was compared to perception of slipperiness. The surface roughness () related very well both AHP (r=0.95) and ramp test (r=0.92). The high significant correlation (r=0.90) was found between AHP and HSL ramp test.The HSL ramp test values (Coefficient of Friction, COF) according to subjective evaluation were divided into two categories. There were high correlations between test results (subjective evaluation, HSL ramp test) and surface roughness in Rz. Perception rating obtained with AHP showed a high correlation with COF obtained with HSL ramp test.
Resistive Switching Memory Devices Based on Proteins (2015)

Resistive switching memory constitutes a prospective candidate for next-generation data storage devices. Meanwhile, naturally occurring biomaterials are promising building blocks for a new generation of environmentally friendly, biocompatible, and biodegradable electronic devices. Recent progress in using proteins to construct resistive switching memory devices is highlighted. The protein materials selection, device engineering, and mechanism of such protein-based resistive switching memory are discussed in detail. Finally, the critical challenges associated with protein-based resistive switching memory devices are presented, as well as insights into the future development of resistive switching memory based on natural biomaterials.
Allergic Skin Disorders and Mastocytosis (1992)

THIS CHAPTER reviews the common and uncommon immunologically mediated diseases of the skin. Newer information concerning the pathogenesis of these diseases, reviewed herein, promises to improve the diagnosis and treatment of these conditions. <h3>URTICARIA AND ANGIOEDEMA</h3> Urticaria consists of blanchable, erythematous, edematous papules and plaques, usually pruritic, ranging from 1 to 2 mm to several centimeters in diameter, often with serpiginous borders. Individual lesions are transient, infrequently persisting. longer than 24 to 48 hours. Characterized by well-demarcated swelling of deeper skin structures and subcutis (with a predilection for palms, soles, and periorbital-perioral areas), angioedema may present as nonpitting edema. The overlying skin appears normal and is nonpruritic; a burning discomfort may occur. <h3>Incidence</h3> Urticaria and angioedema are common.<sup>1,2</sup>The incidence in the general population is approximately 15%. Women are more frequently afflicted, and onset may occur at any age, with peak incidence in the second through fourth decades of
Liver transplantation for hepatitis B cirrhosis: clinical sequela of passive immunization (1996)

High-dose HBIg prevented HBV infection of the allograft in 29 of 32 patients transplanted for HBV cirrhosis with three non-HBV associated deaths. The intravenous infusion of HBIg was frequently associated with minor side effects that were safely tolerated by patients. The risk of HCV transmission and mercury toxicity are minimal, but support the need for a new intravenous formulation of HBIg. HBIg therapy successfully decreased post-OLTx HBV recurrence with no clinical events associated with immunosuppression. Patients did non experience allergic or infusion-related complications that altered or terminated therapy. Manufacturing modifications of HBIg may allow for improved patient tolerance and decreased risks.
High Performance Parallelization of Boyer-Moore Algorithm on Many-Core Accelerators (2014)

Boyer-Moore (BM) algorithm is a single pattern string matching algorithm. It is considered as the most efficient string matching algorithm and used in many applications. The algorithm first calculates two string shift rules based on the given pattern string in the preprocessing phase. These rules help skip parts of the target input string where there is no match to be found. Using the two shift rules, pattern matching operations are performed against the target input sting in the second phase. The second phase is a time consuming process and needs to be parallelized to achieve the high performance string matching. In this paper, we parallelize the BM algorithm on the latest many core accelerators such as the Intel Xeon Phi and the Nvidia Tesla K20 GPU, along with the general-purpose multi-core processors. We partition the target input data amongst multiple threads for parallel execution. Data lying on the threads' boundaries need to be copied redundantly so that the pattern string lying on the boundary can be found. As the target length increases, the algorithm incurs increased matching operations. Also, as the pattern length increases, the number of possible matches decreases. This can potentially lead to the unbalanced workload distribution among threads. Furthermore, the redundant data copy significantly overloads the on-chip shared memories of the GPU for a large number of threads. We use the dynamic scheduling and the multithreading techniques to solve the load balancing problem. We also use the algorithmic cascading technique to reduce the burden on the shared memories of the GPU. Our parallel implementation leads to ~17-times speedup on the Xeon Phi and ~45-times speedup on the Nvidia Tesla K20GPU compared with a serial implementation on the host Intel Xeon processor.
Analysis of ways to secure group control for autonomous mobile robots (2017)

The aim of this paper is to analyze the ways of providing security for mobile robots groups control (MRGC) and to develop a security protocol for MRGC under limited computational and power resources away from the controlled area. The solution for this problem assumes features of group control systems and robot systems from the security point of view. The main problem connected with the development of a security system for mobile robots is the distinction of this type of the network from other networks. This demands the development of special methods and approaches that should take many specific factors such as limitations of computational resources and power into account. The proposed solution for MRGC is based on the use of trust concept for finding the validity of nodes and finding targets. In contrast to the existing approaches, this protocol uses several parameters to evaluate the trust that allows to expand the range of repelled attacks.
Memory size reduction of the novel look-up-table method using symmetry of Fresnel zone plate (2011)

Novel look-up table (N-LUT) method to dramatically reduce the number of pre-calculated interference patterns required for generation of digital holograms was proposed. In this method, the N-LUT contains only the fringe patterns of the object points with unity magnitudes located at each center of the depth-dependent image planes of the object. This principal fringe pattern (PFP) can be regarded as the Fresnel zone pattern (FZP) computed at each depth that has reflection symmetry in geometry. Therefore, if we have only half of the PFP, we can generate the computer generated holography (CGH) without the loss of image quality. But the memory size of LUT could be reduced by half.
A fully capable bidirectional debugger (2000)

The goal of this research project is to develop a bidirectional program debugger with which one can move as easily backwards as current debuggers move forward. We believe this will be a vastly more useful debugger. A programmer will be able to start at the manifestation of a bug and proceed backwards investigating how the program arrived at the incorrect state, rather than the current and often tedious practice of the user stepping and breakpointing monotonically forward and then being forced to start over from the beginning if they skip past a point of interest.Our experimental debugger has been implemented to work with C and C++ programs on Digital/Compaq Alpha based UNIX workstations.