gebhart/patrepeval huggingface dataset:
A Tribute To Milan Novák (2018)

Research Article| October 23, 2018 A Tribute To Milan Novák Radek Škoda; Radek Škoda Guest Editors Search for other works by this author on: GSW Google Scholar Pietro Vignola; Pietro Vignola Guest Editors Search for other works by this author on: GSW Google Scholar Axel Müller; Axel Müller Guest Editors Search for other works by this author on: GSW Google Scholar Lee A. Groat Lee A. Groat Editor Search for other works by this author on: GSW Google Scholar Author and Article Information Radek Škoda Guest Editors Pietro Vignola Guest Editors Axel Müller Guest Editors Lee A. Groat Editor Publisher: Mineralogical Association of Canada First Online: 23 Oct 2018 Online Issn: 1499-1276 Print Issn: 0008-4476 © 2018 Mineralogical Association of Canada The Canadian Mineralogist (2018) 56 (4): 357–363. https://doi.org/10.3749/canmin.INT007 Article history First Online: 23 Oct 2018 Cite View This Citation Add to Citation Manager Share Icon Share Facebook Twitter LinkedIn MailTo Tools Icon Tools Get Permissions Search Site Citation Radek Škoda, Pietro Vignola, Axel Müller, Lee A. Groat; A Tribute To Milan Novák. The Canadian Mineralogist 2018;; 56 (4): 357–363. doi: https://doi.org/10.3749/canmin.INT007 Download citation file: Ris (Zotero) Refmanager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentBy SocietyThe Canadian Mineralogist Search Advanced Search This thematic issue of The Canadian Mineralogist, comprising contributions to the 8th International Symposium of Granitic Pegmatites PEG2017 held in Kristiansand, Norway, in 2017, is dedicated to Milan Novák, a distinguished researcher in the field of pegmatite mineralogy and petrology. Milan Novák was born in Vyškov, a small town close to Brno, Czechoslovakia, in October 1952 and started to collect minerals at the age of about 10. He took his Ms degree in Geology at the Masaryk University in Brno (1977) and obtained his PhD degree in Mineralogy and Petrology at Charles University in Prague (1988) defending the... You do not have access to this content, please speak to your institutional administrator if you feel you should have access.
Progress Toward Measles Elimination — Nepal, 2007–2014 (2016)

In 2013, the 66th session of the Regional Committee of the World Health Organization (WHO) South-East Asia Region (SEAR) established a goal to eliminate measles and to control rubella and congenital rubella syndrome (CRS) in SEAR by 2020. Current recommended measles elimination strategies in the region include 1) achieving and maintaining ≥95% coverage with 2 doses of measles-containing vaccine (MCV) in every district, delivered through the routine immunization program or through supplementary immunization activities (SIAs); 2) developing and sustaining a sensitive and timely measles case-based surveillance system that meets minimum recommended performance indicators; 3) developing and maintaining an accredited measles laboratory network; and 4) achieving timely identification, investigation, and response to measles outbreaks. In 2013, Nepal, one of the 11 SEAR member states, adopted a goal for national measles elimination by 2019. This report updates a previous report and summarizes progress toward measles elimination in Nepal during 2007-2014. During 2007-2014, estimated coverage with the first MCV dose (MCV1) increased from 81% to 88%. Approximately 3.9 and 9.7 million children were vaccinated in SIAs conducted in 2008 and 2014, respectively. Reported suspected measles incidence declined by 13% during 2007-2014, from 54 to 47 cases per 1 million population. However, in 2014, 81% of districts did not meet the measles case-based surveillance performance indicator target of ≥2 discarded non-measles cases per 100,000 population per year. To achieve and maintain measles elimination, additional measures are needed to strengthen routine immunization services to increase coverage with MCV1 and a recently introduced second dose of MCV (MCV2) to ≥95% in all districts, and to enhance sensitivity of measles case-based surveillance by adopting a more sensitive case definition, expanding case-based surveillance sites nationwide, and ensuring timely transport of specimens to the accredited national laboratory.
Modulation of Signal-Transducing Function of Neuronal Membrane Na+,K by Endogenous Ouabain and Low-Power Infrared Radiation Leads to Pain Relief (2012)

Effects of infrared (IR) radiation generated by a low-power Co2-laser on sensory neurons of chick embryos were investigated by organotypic culture method. Low-power IR radiation firstly results in marked neurite suppressing action, probably induced by activation of Na+,K+-ATPase signal-transducing function. A further increase in energy of radiation leads to stimulation of neurite growth. We suggest that this effect is triggered by activation of Na+,K+-ATPase pumping function. Involvement of Na+,K+-ATPase in the control of the transduction process was proved by results obtained after application of ouabain at very low concentrations. Physiological significance of low-power IR radiation and effects of ouabain at nanomolar level was investigated in behavioral experiments (formalin test). It is shown that inflammatory pain induced by injection of formalin is relieved both due to ouabain action and after IR irradiation.
A guide for measurement of circulating metabolic hormones in rodents: Pitfalls during the pre-analytical phase (2012)

Researchers analyse hormones to draw conclusions from changes in hormone concentrations observed under specific physiological conditions and to elucidate mechanisms underlying their biological variability. It is, however, frequently overlooked that also circumstances occurring after collection of biological samples can significantly affect the hormone concentrations measured, owing to analytical and pre-analytical variability. Whereas the awareness for such potential confounders is increasing in human laboratory medicine, there is sometimes limited consensus about the control of these factors in rodent studies. In this guide, we demonstrate how such factors can affect reliability and consequent interpretation of the data from immunoassay measurements of circulating metabolic hormones in rodent studies. We also compare the knowledge about such factors in rodent studies to recent recommendations established for biomarker studies in humans and give specific practical recommendations for the control of pre-analytical conditions in metabolic studies in rodents.
Gold Films Deposited over Regular Arrays of Polystyrene Nanospheres as Highly Effective SERS Substrates from Visible to NIR (2006)

Gold nanostructured films of various thicknesses (15, 30, and 60 nm) are deposited over regular arrays of polystyrene nanospheres in an attempt to evaluate their potential as SERS-active substrates. Atomic force microscopy is used to topographically characterize the substrates as well as to ensure the thickness of the deposited gold films. The optical response of the prepared substrates recommends their use in SERS experiments with multiple laser lines from visible and NIR spectral domains. The assessment of the substrates' SERS activity is performed by using the 532, 633, and 830 nm excitation lines and different average enhancement factor (EF) values are obtained depending on the film thickness and employed laser line. The 60 nm gold nanostructured film generates the greatest local electromagnetic field confinement under NIR excitation and consequently gives rise to maximum SERS enhancement. The large tunability of surface plasmon excitation combined with the advantage of relatively high exhibited average EF values obtained under NIR excitation recommends these substrates as outstanding candidates for upcoming investigations of biological relevant molecules.
Extended Oxygen Delignification. Part I: Effects of Multi-stage Oxygen Bleaching on Softwood Kraft Pulp and Residual Lignin. Comparison with Chlorine Dioxide Delignification (2004)

A softwood kraft pulp was submitted to successive oxygen stages (O, OO, OOO). Residual lignin after treatment was extracted by acid hydrolysis and characterised by 13C NMR and GPC. The progressive decrease in the efficiency of the O treatment in a multiple O sequence was explained by the poor reactivity of some of the free phenolic lignin structures with oxygen. Oxygen (O) and chlorine dioxide (D) delignification were compared. Contrary to OOO , the DEDEDE... process led to total delignification. Both chemicals attacked the free phenolic groups in lignin as evidenced by the important decrease in their number measured after treatment. However, their disappearance was more complete in the case of ClO{2}. Moreover a higher number of ClO{2} H groups were formed in the latter case. According to mechanisms given for chlorine dioxide delignification, hypochlorous acid (ClOH) is produced as by-product during a D stage and would react with residual lignin. This would explain the better efficiency of D compared to O stages.
Studies on the pathogenesis of streptococcal infection in cultured yellowtails <i>Seriola</i> spp.: effect of the cell free culture on experimental streptococcal infection (1979)

Abstract. A previous paper has revealed that experimental streptococcal infection was associated with a rapid growth of the intestinal bacteria, suggesting association of the condition with an exotoxin. The present study was undertaken to see the effect of the exotoxin on the streptococcal infection by administering cell free culture before the bacterial challenge. Cell free culture of Streptococcus sp. strain YT‐3 was inoculated intramuscularly at a dosage of 0–5 ml per 100 g body weight 1 h prior to bacterial challenge. Three fish were killed at intervals after challenge for viable counting of bacteria in the viscera and blood. Intramuscular inoculation with either low virulent or virulent bacteria alone at dosages of 10 6 to 10 7 cells did not produce the disease in the fish, with almost complete clearance of the bacteria from the viscera and blood within 120 h. When the exotoxin was inoculated intramuscularly prior to the bacterial challenge, however, either low virulent or virulent bacteria at 10 6 to 10 7 cells could produce fatal infection with prominent streptococcal clinical signs.
Polyurethane/Dermatan Sulfate Copolymers as Hemocompatible, Non‐Biofouling Materials (2010)

The range of application of polyurethanes has been limited by their poor hemocompatibility and inability to resist non-specific binding of biomolecules and cells. In this work, a non-adhesive PU-based material was synthesized via the copolymerization of PU with dermatan sulfate. Incorporation of DS into the PU backbone dramatically increased material hydrophilicity and decreased protein adsorption. The in vitro adhesion of several cell types, including platelets, also significantly decreased with increasing DS content. Both the physical and biological properties of the DS contributed to the anti-adhesive properties of the PU/DS copolymer, and this anti-adhesive nature of PU/DS renders this new biomaterial attractive for blood-contacting or non-fouling applications.
A short enantioselective synthesis of 3-epi-jaspine B and (+)-oxybiotin via an intramolecular tandem desilylation oxa-Michael addition strategy (2014)

A new synthesis of cytotoxic 3-<italic>epi</italic>-jaspine B (34.7% overall yield; 97% ee) and (+)-oxybiotin (21.2% overall yield; 97% ee) is described starting from <italic>cis</italic>-2-butene-1,4-diol. The key reactions employed in the synthesis are Sharpless asymmetric epoxidation and a novel tandem desilylation-oxa Michael addition reaction.
[Enoximone/dobutamine comparison in chronic congestive cardiac insufficiency with low cardiac output]. (1990)

In severe chronic congestive cardiac failure the physician has the choice of two families of positive inotropic agents, the direct sympathomimetics and the phosphodiesterase inhibitors. The aim of the study was to compare the efficacy and tolerance of enoximone and dobutamine in this indication. Twenty patients with severe chronic cardiac failure with a cardiac index of less than 2.2 l/min/m2 and pulmonary capillary pressure of over 20 mmHg were randomised into two groups in an open trial. One group received enoximone 50 micrograms/kg/min for 30 minutes then 10 micrograms/kg/min and the other received dobutamine 10 micrograms/kg/min. The two groups were comparable. Results were analysed 12 hours after starting therapy, well after the loading dose of enoximone and before the appearance of tolerance to dobutamine. Neither drug caused a significant change in heart rate or mean blood pressure. The pressure-rate product did not increase significantly with enoximone (+9.2% NS) in contrast with the dobutamine group in which a significant elevation was observed (+23.5%, p less than 0.05). The cardiac index increased with enoximone (+61.0%, p less than 0.01) and with dobutamine (+32.1%, p less than 0.02). This resulted mainly from an increase in the systolic index (+45.5%, p less than 0.05 with enoximone and +30.1%, p less than 0.05 with dobutamine). Pulmonary capillary pressure and total systemic resistance decreased with enoximone (-29.1%, p less than 0.001 and -36.7%, p less than 0.05 respectively) and with dobutamine (-23.4%, p less than 0.001 and -20.7%, p less than 0.05 respectively).(ABSTRACT TRUNCATED AT 250 WORDS)
Probability of Identification: Adulteration of American Ginseng with Asian Ginseng (2013)

The AOAC INTERNATIONAL guidelines for validation of botanical identification methods were applied to the detection of Asian Ginseng [Panax ginseng (PG)] as an adulterant for American Ginseng [P. quinquefolius (PQ)] using spectral fingerprints obtained by flow injection mass spectrometry (FIMS). Samples of 100% PQ and 100% PG were physically mixed to provide 90, 80, and 50% PQ. The multivariate FIMS fingerprint data were analyzed using soft independent modeling of class analogy (SIMCA) based on 100% PQ. The Q statistic, a measure of the degree of non-fit of the test samples with the calibration model, was used as the analytical parameter. FIMS was able to discriminate between 100% PQ and 100% PG, and between 100% PQ and 90, 80, and 50% PQ. The probability of identification (POI) curve was estimated based on the SD of 90% PQ. A digital model of adulteration, obtained by mathematically summing the experimentally acquired spectra of 100% PQ and 100% PG in the desired ratios, agreed well with the physical data and provided an easy and more accurate method for constructing the POI curve. Two chemometric modeling methods, SIMCA and fuzzy optimal associative memories, and two classification methods, partial least squares-discriminant analysis and fuzzy rule-building expert systems, were applied to the data. The modeling methods correctly identified the adulterated samples; the classification methods did not.
Geometric Complexity Theory VII: Nonstandard quantum group for the plethysm problem (2007)

This article describes a {\em nonstandard} quantum group that may be used to derive a positive formula for the plethysm problem, just as the standard (Drinfeld-Jimbo) quantum group can be used to derive the positive Littlewood-Richardson rule for arbitrary complex semisimple Lie groups. The sequel \cite{GCT8} gives conjecturally correct algorithms to construct canonical bases of the coordinate rings of these nonstandard quantum groups and canonical bases of the dually paired nonstandard deformations of the symmetric group algebra. A positive $#P$-formula for the plethysm constant follows from the conjectural properties of these canonical bases and the duality and reciprocity conjectures herein.
Modeling, analysis, and self-management of electronic textiles (2003)

Scaling in CMOS device technology has made it possible to cheaply embed intelligence in a myriad of devices. In particular, it has become feasible to fabricate flexible materials (e.g., woven fabrics) with large numbers of computing and communication elements embedded into them. Such computational fabrics, electronic textiles, or e-textiles have applications ranging from smart materials for aerospace applications to wearable computing. This paper addresses the modeling of computation, communication and failure in e-textiles and investigates the performance of two techniques, code migration and remote execution, for adapting applications executing over the hardware substrate, to failures in both devices and interconnection links. The investigation is carried out using a cycle-accurate simulation environment developed to model computation, power consumption, and node/link failures for large numbers of computing elements in configurable network topologies. A detailed analysis of the two techniques for adapting applications to the error prone substrate is presented, as well as a study of the effects of parameters, such as failure rates, communication speeds, and topologies, on the efficacy of the techniques and the performance of the system as a whole. It is shown that code migration and remote execution provide feasible methods for adapting applications to take advantage of redundancy in the presence of failures and involve trade offs in communication versus memory requirements in processing elements.
Architectures d'interrupteur de puissance autocommuté (2010)

International audience
Optical performance of integrated 1.5 μm grating wavelength-demultiplexer on InP-based waveguide (1989)

The performance of a monolithic spectrometer operating by total internal reflection of a slab-guided mode from vertical dry-etched mirrors is reported. Device outputs are almost diffraction-limited and exhibit a signal-to-noise ratio of 15–20 dB. Losses for the collimating mirrors and the grating are 2 and 2.5 dB, respectively.
LES of different flow states around a cylinder plate configuration and corresponding aeroacoustic effects (2009)

Colloque avec actes et comité de lecture. Internationale.
On emission certification of heavy-duty hybrid electric vehicles using hardware-in-the-loop simulation (2011)

The objective of this report is to present an investigation on a test method for heavy-duty hybrid electric vehicles using hardware-inthe-loop simulations for type-approval-tests. Traditionally, certification of heavy-duty vehicle emissions are done in an engine test bench using an engine brake and one or several predefined, standardized engine cycles. The introduction of hybrid technology leads to new demands for type-approval. The number of possible vehicle combinations becomes immense, since for a heavy-duty customer it is possible to select engine size, transmission, gear ratios, battery size, electric motor size, number of drive axles etc., this means that almost no truck is the same. In Japan a method for certification of heavy-duty hybrid vehicles using hardwarein-the-loop has been developed. The method uses measured data from some components (battery, electric motors and internal combustion engine), these data are then used in a simulation model, running against the real control system. The method shows good agreement with runs on chassis dynamometer. The report studies the method for certification issued in Japan. The aim is to generate knowledge in the area for understanding the requirements that need to be placed on a hardware-in-the-loop simulation type-approval method. In addition to studies of the method, simulation models suitable for hardware-in-the-loop simulation are developed and presented. The report also shows a case study on what problems that occur when connecting a ”real” hybrid vehicle controller to the hardware-in-the-loop setup.
Optische Kohärenztomografie in der Multiplen Sklerose (2011)

Zusammenfassung Die Multiple Sklerose (MS) ist eine entzündliche und degenerative Autoimmunerkrankung des Zentralnervensystems. Die Magnetresonanztomografie erlaubt über eine quantitative Bestimmung der Hirnparenchymfraktion (brain parenchymal fraction, BPF) sowie der T1-Hypointensitäten (T1 hypointensities/ black holes) die Darstellung des Ausmaßes axonaler bzw. neuronaler Schädigung. Mittels optischer Kohärenztomografie (optical coherence tomography, OCT) konnten mehrere Querschnittsstudien eine stadienabhängige Abnahme der mittleren Schichtdicke der Retinanervenfasern bei MS-Patienten nachweisen. Erste longitudinale Daten zeigen, dass auch ohne Optikusneuritis in der Vorgeschichte die Retinanervenfaserschicht bei MS über das altersnormale Maß hinaus im Verlauf der Erkrankung abnimmt. Die Parameter der retinalen Atrophie in der OCT korrelieren darüber hinaus mit dem Ausmaß der Hirn atrophie gemessen an der BPF im MRT. Weitere longitudinale Studien mit neuester OCT-Technologie sowie interventionelle Studien müssen zukünftig zeigen, inwieweit das OCT als Parameter für das Ausmaß der Neurodegeneration in klinische MS-Studien integriert werden kann.
The Pdx1 family is structurally and functionally conserved between <i>Arabidopsis thaliana</i> and <i>Ginkgo biloba</i> (2008)

Vitamin B6 is one of the most important compounds in living organisms, and its biosynthesis has only recently been understood. Because it is required for more than 100 biochemical reactions, lack of the vitamin is fatal. This is of special importance to mammals and humans, which cannot biosynthesize the vitamin and thus depend on its external uptake. Here we describe the cloning of a vitamin B6 biosynthetic gene GbPDX1 from Ginkgo biloba. The gene is expressed in seeds, leaf and trunk tissue. Using yeast 2-hybrid and pull-down assays, we show that the protein can interact with itself and with members of Arabidopsis thaliana AtPDX1 and AtPDX2 families. Furthermore, we prove the function of GbPDX1 in vitamin B6 biosynthesis by complementation of an Arabidopsis AtPDX1.3 mutant rsr4-1, at the phenotypical level and increasing vitamin B6 levels caused by ectopic GbPDX1 expression in the mutant background. Overall, this study provides a first description of Ginkgo vitamin B6 metabolism, and demonstrates a high degree of conservation between Ginkgo and Arabidopsis.
Tracking the Odysseys of Juvenile Schistosomes to Understand Host Interactions (2008)

[Extract] The prospects confronting a new-born schistosome cercaria are formidable. That some of these microscopic helminths successfully negotiate the tortuous route from snail to human vasculature is a truly remarkable feature of adaptive biology. After escaping the birth pore of its parental sporocyst, a cercaria (at least we infer from studies of other digeneans [1]) swims and crawls through the snail body cavity before it burrows through a pre-formed escape tunnel to the aquatic environment. Once in that milieu, a cyclical suite of swimming behaviours positions the cercaria for its potential assault on the skin of an available host, should one appear. Upon skin penetration, the larva (now called a schistosomulum) sits within the skin for up to 72 hours before tracking to the lung, whereupon it re-enters a second static phase. This journey takes the organism through three distinct environments (five if we include the solid integuments of snail and human hosts), incorporates a wholesale remodelling of the surface membrane, and includes two poorly understood periods of relative immobility in the skin and the lung. Further development in the liver is required before the adults reach their ultimate destination in the vasculature of the intestine or bladder. How the juvenile stages of schistosomes negotiate these environments is of intense interest, not the least because protective immunity in schistosome infections, when it occurs, appears to be directed against the early intra-host stages, with the principal target being the lung stage schistosomulum [2].