gebhart/patrepeval huggingface dataset:
Vascular Endothelial Growth Factor Stimulates Proliferation but Not Migration or Invasiveness in Human Extravillous Trophoblast1 (1998)

Vascular endothelial growth factor (VEGF) is a homodimeric glycoprotein that promotes angiogenesis and vascular hyperpermeability and interacts with two receptors, fms-like tyrosine kinase (Flt-1) and kinase domain-containing region (KDR). In situ localization in the pregnant human uterus revealed that VEGF mRNA is expressed primarily by the maternal decidua, whereas the receptor Flt-1 is expressed primarily by chorionic vascular endothelium and trophoblast cells-in particular, the extravillous trophoblast (EVT). We examined whether the mRNA and protein of VEGF and its receptors are expressed by invasive human first-trimester EVT cells propagated in culture and whether VEGF influences EVT cell proliferation, migration, and invasiveness. Proliferation was assessed by the uptake of [3H]thymidine. Invasion and migration across transwells were assessed by the degree of cellular transgression of a Millipore membrane coated, respectively, with and without Matrigel. Results of immunocytochemical and reverse transcription-polymerase chain reaction analysis revealed that both protein and mRNA of VEGF, Flt-1, and KDR were expressed by cultured normal EVT cells as well as their premalignant derivative produced by SV-40 Tag-immortalization, and BeWo choriocarcinoma cells. Under serum-free conditions, exogenous VEGF121 (the non-heparin-binding isoform) stimulated proliferation of all three cell lines in a concentration-dependent manner. The effects were abolished with a VEGF-neutralizing antibody. The same stimulatory effects on EVT cells were also seen with exogenous VEGF165 (a heparin-binding isoform), only after a cleaving of the heparin-binding domain with plasmin or a blocking of heparin binding sites with excess soluble heparan sulphate proteoglycans (HSPGs), suggesting a regulatory role of HSPGs. However, VEGF121 and VEGF165 (with and without the HSPG pretreatment) had no effect on normal EVT cell migration or invasiveness. Thus, VEGF may provide a dual role in angiogenesis and EVT cell proliferation during normal placental development.
Insulating films on semiconductors (1979)

Report on Insulating films on semiconductors, Institute of Physics/IEE, 2-4 July 1979 at the University of Durham.
New system for wiggler fabrication and testing (1987)

A system approach is taken for the fabrication and testing of wigglers for free-electron lasers. Emphasis is placed on convenient, practical, assembly procedures that produce wigglers with high fields, two-plane focusing, and facilities for in-place adjustments. Equal emphasis is place on rapid and precise techniques for measuring field errors, both before final assembly and afterward, during wiggler operation. 10 refs., 12 figs.
Morphological instability in freezing colloidal suspensions (2006)

We present a linear stability analysis of a planar ice interface during unidirectional solidification of a hard-sphere colloidal suspension. We find that the interface can become unstable due to constitutional supercooling, yielding a new mechanism for pattern formation in colloidal systems. The interfacial stability is shown to depend strongly on the size and concentration of the particles. Increasing the particle radius tends to stabilize the interface, while increasing the concentration has a destabilizing effect. Additional effects that may influence the stability and morphology of such a system are described.
[Pregnancy and periodontal disease--is there a relation?]. (2008)

Pregnancy complications, especially low birth weight (defined as birth weight less than 2.500 kilograms (kg)), pre-term delivery (less than 37 weeks) and pre-ecclampsia (elevated maternal blood pressure), continue to be a significant public health issue in both developed and developing countries. Recent data indicate that periodontal disease might confer risk for several systemic disorders. The relationship between periodontal diseases in pregnancy and obstetric complications has been increasingly investigated, showing inconclusive results. The purpose of this study is to review the current literature regarding the influence of periodontal status on pregnancy outcome, including the effect of periodontal treatment. Further research in this area is required, particularly with respect to the effect of population differences on this potential association between periodontal diseases and pregnancy complications as well as on the exact mechanism of this association. Since pregnancy tends to influence periodontal status, and considering the potential reported relation between periodontal disease and pregnancy complications, careful periodontal diagnosis and treatment before as well as during pregnancy is warranted.
Investigation of Feasibility of Integral Gas Turbine Engine Solid Particle Inlet Separators. Phase II. Feasibility Demonstration (1971)

Abstract : Two different sand and dust particle separator test rigs were fabricated and tested to evaluate separation efficiency, aerodynamic performance characteristics, and operation in rain and foliage ingestion conditions. The semi-reverse-flow separator utilized fixed turning vanes on a contoured hub to induce swirl in an annular duct. At design airflow of 8 lb/sec and 40% scavenge flow, the semi-reverse-flow separator demonstrated 88.5% separation efficiency with AC coarse test dust at an average pressure drop of 2.8 in. H2O. The powered mixed-flow separator attempted to utilize the strong centrifugal field available in a mixed-flow impeller turning at the high speeds characteristic of small gas turbine engines to achieve particle separation. At the design airflow of 8 lb/ sec, it demonstrated a maximum separation efficiency of 58.7% with 8.4% scavenge flow and an average pressure rise of 6.76 psi. Both separator concepts were determined to be feasible and the semi-reverse-flow separator is considered to be superior to current engine air particle separators for the majority of aspects investigated.
60-GHz 5-bit Phase Shifter With Integrated VGA Phase-Error Compensation (2013)

A 57-64-GHz low phase-error 5-bit switch-type phase shifter integrated with a low phase-variation variable gain amplifier (VGA) is implemented through TSMC 90-nm CMOS low-power technology. Using the phase compensation technique, the proposed VGA can provide appropriate gain tuning with almost constant phase characteristics, thus greatly reducing the phase-tuning complexity in a phased-array system. The measured root mean square (rms) phase error of the 5-bit phase shifter is 2° at 62 GHz. The phase shifter has a low group-delay deviation (phase distortion) of +/- 8.5 ps and an excellent insertion loss flatness of ±0.8 dB for a specific phase-shifting state, across 57-64 GHz. For all 32 states, the insertion loss is 14.6 ± 3 dB, including pad loss at 60 GHz. For the integrated phase shifter and VGA, the VGA can provide 6.2-dB gain tuning range, which is wide enough to cover the loss variation of the phase shifter, with only 1.86° phase variation. The measured rms phase error of the 5-bit phase shifter and VGA is 3.8° at 63 GHz. The insertion loss of all 32 states is 5.4 dB, including pad loss at 60 GHz, and the loss flatness is ±0.8 dB over 57-64 GHz. To the best of our knowledge, the 5-bit phase shifter presents the best rms phase error at center frequency among the <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">V</i> -band switch-type phase shifter.
Spectral Properties of Preconditioned Rational Toeplitz Matrices: The Nonsymmetric Case (1993)

Various preconditioners for symmetric positive-definite (SPD) Toeplitz matrices in circulant matrix form have recently been proposed. The spectral properties of the preconditioned SPD Toeplitz matrices have also been studied. In this research, Strang’s preconditioner $S_N $ and our preconditioner $K_N $ are applied to an $N \times N$ nonsymmetric (or nonhermitian) Toeplitz system $T_N {\bf x} = {\bf b}$. For a large class of Toeplitz matrices, it is proved that the singular values of $S_N^{ - 1} T_N $ and $K_N^{ - 1} T_N $ are clustered around unity except for a fixed number independent of N. If $T_N $ is additionally generated by a rational function, the eigenvalues of $S_N^{ - 1} T_N $ and $K_N^{ - 1} T_N $ can be characterized directly. Let the eigenvalues of $S_N^{ - 1} T_N $ and $K_N^{ - 1} T_N $ be classified into the outliers and the clustered eigenvalues depending on whether they converge to 1 asymptotically. Then, the number of outliers depends on the order of the rational generating function, and the clustering radius is proportional to the magnitude of the last elements in the generating sequence used to construct the preconditioner. Numerical experiments are provided to illustrate our theoretical study.
Porters creek dam - treatment for iron reduction (1989)

Due to the poor quality of the untreated water supply to the Milton-Ulladulla District, the water storage in Porters Creek Dam was treated with liquid aluminium sulphate (alum) to reduce the concentration of iron. The pH was initially raised using quick lime to improve the flocculation and subsequent settling caused by the alum. Two methods were used to distribute the chemicals. The quick lime was spread using a crop dusting aeroplane and the alum was partly spread by plane and partly by barge. The advantages of each method are discussed. Although the procedure will probably be required prior to the summer each year, the water quality has been improved sufficiently to delay the need for full filtration treatment.
The New Methodology (2001)

In the past few years there's been a rapidly growing interest in “lightweight” methodologies. Alternatively characterized as an antidote to bureaucracy or a license to hack they've stirred up interest all over the software landscape. In this essay I explore the reasons for lightweight methods, focusing not so much on their weight but on their adaptive nature and their people first orientation. I also give a summary and references to the processes in this school and consider the factors that should influence your choice of whether to go down this newly trodden path.
Low Temperature Phase Relations in the System H2O-NaCl-FeCl2 (1998)

The low temperature phase behavior of the system H2O-NaCl-FeCl2 was examined using synthetic fluid inclusions. Experiments were conducted along the 5 wt% NaCl (relative to the total solution) pseudobinary, with FeCl2 concentrations varying from 2 to 33 wt%, and along the pseudobinary defined by mixing known amounts of FeCl2-4H2O with a 5 wt% NaCl solution, with final FeCl2 concentrations varying from 0 to 29 wt%. Synthetic fluid inclusions in quartz were prepared in cold-seal pressure vessels at 500 degrees C - 800 degrees C and 2 or 3 kilobars. The fO2 conditions were controlled by the Ni-NiO equilibrium curve. The liquid released from the capsule upon opening was initially colorless, but turned yellow-orange after contact with atmospheric O2. The clear color is characteristic of ferrous iron solutions, whereas the yellow-orange color is consistent with the presence of Fe3+ in solution. This color change suggested that the unopened capsules initially contained ferrous iron in solution, which oxidized to ferric iron when exposed to the atmosphere. Borisenko (1977) reported a eutectic temperature of -37 degrees C for the system H2O-NaCl-FeCl2. In this study, it was not possible to verify this temperature due to the persistence of a metastable liquid down to liquid N2 temperatures (~-196 degrees C). Final ice melting temperatures were obtained for concentrations less than 24 wt% FeCl2 and show a decrease in temperature with increase in FeCl2 concentration. For more concentrated solutions, final melting temperatures could not be obtained because the samples could not be frozen.
Accuracy of selective extraction procedures for metal speciation in model aquatic sediments (1987)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAccuracy of selective extraction procedures for metal speciation in model aquatic sedimentsCarolyn. Kheboian and Christopher F. BauerCite this: Anal. Chem. 1987, 59, 10, 1417–1423Publication Date (Print):May 15, 1987Publication History Published online1 May 2002Published inissue 15 May 1987https://pubs.acs.org/doi/10.1021/ac00137a010https://doi.org/10.1021/ac00137a010research-articleACS PublicationsRequest reuse permissionsArticle Views833Altmetric-Citations311LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
A Description of the Technique for Nuclear Transplantation in<i>Xenopus laevis</i> (1960)

ABSTRACT Technical details are given of a method of transplanting embryonic nuclei in X. laevis. This technique is based on Briggs & King’s method for R. pipiens. Owing to certain differences between the eggs of Rana and Xenopus, their technique has been modified for Xenopus. The main modification for Xenopus concerns the use of ultra-violet irradiation instead of enucleation by a needle. Differences between transplantation techniques for Rana and Xenopus are unlikely to account for the differences in experimental results obtained with these species.
Scalable parallel matrix multiplication on distributed memory parallel computers (2002)

Consider any known sequential algorithm for matrix multiplication over an arbitrary ring with time complexity O(N <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">α</sup> ), where 2 < α<3. We show that such an algorithm can be parallelized on a distributed memory parallel computer (DMPC) in O (log N) time by using N <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">α</sup> /log N processors. Such a parallel computation is cost optimal and matches the performance of PRAM. Furthermore, our parallelization on a DMPC can be made fully scalable, that is, for all 1<p<Nα <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">α</sup> /log N, multiplying two NxN matrices can be performed by a DMPC with p processors in O(N <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">α</sup> /p) rime, i.e., linear speedup and cost optimality can be achieved in the range [1..N <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">α</sup> /log N]. This unifies all known algorithms for matrix multiplication on DMPC, standard or non-standard, sequential or parallel. Extensions of our methods and results to other parallel systems are also presented. The above claims result in significant progress in scalable parallel matrix multiplication (as well as solving many other important problems) on distributed memory systems, both theoretically and practically.
Neuropsychological profile and clinical effects of arginine treatment in children with creatine transport deficiency (2012)

This study provides information to support the effectiveness of L-Arg supplement treatment in CTRT-D patients; in fact the syndromic pattern of cognitive and linguistic deficit presented by CRTR-D patients was partially altered by L-Arg supplementation especially at a qualitative clinical level. Oral L-Arg may represent not only a protective factor towards a further cognitive decline, but can lead to the acquisition of new skills.
간호사의 MBTI 성격유형과 학습조직화와의 관계 (2005)

Purpose: This study was to investigate the degree and pattern of learning organization and MBTI personality type in clinical nurses. Methods: The participants were 685 nurses working in the 8 general hospitals located in Seoul and Incheon. The data were collected by self-reporting questionnaires from April 1 to August 30, 2004. The data were analyzed using SAS program for descriptive statistics and Pearson`s correlation coefficient. Results: The most frequent identified personality type was ISTJ and the least identified personal types was ENFJ, In 4 preference patterns, Extroversion, Sensing, Thinking and Judgement were identified a dominant index in each categories. The mean score of learning organization was 3.47 and the mental model was got the highest score. The EI index had a significant positive correlation with personal mastery. However the TF index had a negative correlation with personal mastery, systems thinking, and mental models, and also the JP index had a negative correlation with 5 learning organization sub categories. Conclusion: With these results, it was identified that the preference patterns on MBTI had the significant correlation with learning organization. So these results will be used to develop the more effective strategies to increase learning organization based on nurse`s personality types.
CT imaging of angiogenesis. (2003)

Tumor angiogenesis has significant implications in the diagnosis and treatment of various solid tumors. With the advent of fast, multi-slice CT scanners, CT imaging techniques capable of qualitative and quantitative analysis of tumor angiogenesis have been the subject of extensive investigation in the past 2 decades. The fundamental bases for CT imaging of angiogenesis are both the transport by blood flow of intravenously administered iodinated contrast material to tissue and the exchange by diffusion of these contrast molecules between the intravascular space and the extravascular interstitial space. With current fast CT scanners both tissue and vascular enhancement can be measured and traced over time at small time intervals to allow detailed modeling of the distribution of contrast agent in tissue. Both compartmental and distributed parameter models for contrast transport and exchange have been developed to quantify from the CT data the following angiogenesis related parameters: tissue blood flow, blood volume, mean transit time, contrast arrival time, capillary permeability surface area product and hepatic arterial fraction in case of the liver. This review addresses the following aspects of CT imaging of angiogenesis: 1) basic concepts related to the understanding of both compartmental and distributed parameter models; 2) comparison between both types of models; 3) practical issues with respect to the measurement of the arterial input function, which is required for the solution of both types of models; and, 4) illustration of the application of a distributed parameter model, the Johnson and Wilson model, in a number of experimental studies.
Sulfonylurea Receptors, Ion Channels, and Fruit Flies (1988)

Recent studies have identified a high-affinity receptor on the plasma membrane of the beta-cell that is specific for all of the sulfonylureas. The most potent second-generation drugs, glyburide and glipizide, bind to the receptor and trigger insulin release at nanomolar concentrations. The affinity to the receptor-ligand interaction of all sulfonylureas correlates with their potency as insulin secretagogues, further implicating receptor occupancy with signal transduction. These drugs also inhibit the electrical activity of ATP-sensitive K+ channels and K+ efflux through these channels. The channels are also closed by the metabolism of the major insulin secretagogues, glucose and the amino acids, which signal insulin release by increasing the ATP level or the [ATP]-to-[ADP] ratio on the cytoplasmic side of the channel. Based on the channel number and the amount of K+ current they pass, it is possible to calculate that these channels control the resting membrane potential of the beta-cell. Inactivation of the ATP-inhibitable K+ channel results in a fall in the resting membrane potential, cell depolarization, and influx of extracellular Ca2+ through the voltage-dependent Ca2+ channel. The rise in intracellular free Ca2+ level triggers exocytosis. Thus, it is now possible to link either a stimulus from the metabolism of insulin secretagogues or the sulfonylureas to ionic and electrical events that elicit insulin release. These data also suggest that the sulfonylurea receptor or a closely associated protein is an ATP-sensitive K+ channel.
The impact of unwanted multimodal notifications (2011)

Multimodal interaction can be used to make home care technology more effective and appropriate, particularly for people with sensory impairments. Previous work has revealed how disruptive notifications in different modalities are to a home-based task, but has not investigated how disruptive unwanted notifications might be. An experiment was conducted which evaluated the disruptive effects of unwanted notifications when delivered in textual, pictographic, abstract visual, speech, earcon, auditory icon, tactile and olfactory modalities. It was found that for all the modalities tested, both wanted and unwanted notifications produced similar reductions in error rate and task success, independent of modality. The results demonstrate the need to control and limit the number of unwanted notifications delivered in the home and contribute to a large body of work advocating the inclusion of multiple interaction modalities.
Graphene-supported SnO2 nanoparticles prepared by a solvothermal approach for an enhanced electrochemical performance in lithium-ion batteries (2012)

SnO2 nanoparticles were dispersed on graphene nanosheets through a solvothermal approach using ethylene glycol as the solvent. The uniform distribution of SnO2 nanoparticles on graphene nanosheets has been confirmed by scanning electron microscopy and transmission electron microscopy. The particle size of SnO2 was determined to be around 5 nm. The as-synthesized SnO2/graphene nanocomposite exhibited an enhanced electrochemical performance in lithium-ion batteries, compared with bare graphene nanosheets and bare SnO2 nanoparticles. The SnO2/graphene nanocomposite electrode delivered a reversible lithium storage capacity of 830 mAh g-1 and a stable cyclability up to 100 cycles. The excellent electrochemical properties of this graphene-supported nanocomposite could be attributed to the insertion of nanoparticles between graphene nanolayers and the optimized nanoparticles distribution on graphene nanosheets.