gebhart/patrepeval huggingface dataset:
Automated identification of security issues from commit messages and bug reports (2017)

The number of vulnerabilities in open source libraries is increasing rapidly. However, the majority of them do not go through public disclosure. These unidentified vulnerabilities put developers' products at risk of being hacked since they are increasingly relying on open source libraries to assemble and build software quickly. To find unidentified vulnerabilities in open source libraries and secure modern software development, we describe an efficient automatic vulnerability identification system geared towards tracking large-scale projects in real time using natural language processing and machine learning techniques. Built upon the latent information underlying commit messages and bug reports in open source projects using GitHub, JIRA, and Bugzilla, our K-fold stacking classifier achieves promising results on vulnerability identification. Compared to the state of the art SVM-based classifier in prior work on vulnerability identification in commit messages, we improve precision by 54.55% while maintaining the same recall rate. For bug reports, we achieve a much higher precision of 0.70 and recall rate of 0.71 compared to existing work. Moreover, observations from running the trained model at SourceClear in production for over 3 months has shown 0.83 precision, 0.74 recall rate, and detected 349 hidden vulnerabilities, proving the effectiveness and generality of the proposed approach.
Privatization and foreign investment in the developing world, 1988-92 (1993)

Foreign direct investment in the developing world has grown rapidly in recent years, making it one of the most important sources of financing to developing countries. The author presents a database on about 1, 100 global privatization transactions from 1988 through 1992. Between 1988 and 1992, developing country governments earned almost US$62 billion in revenues from the sale of state-owned assets. About a third of those revenues came from foreign sources. Privatization in Latin America represents about 66 percent of privatization in the developing world. Privatization in Europe, including Eastern Europe, accounts for 17 percent, and privatization in East Asia, 13 percent. The heaviest foreign participation is in Eastern Europe, primarily for lack of domestic financing. Foreign investors'general participation in privatization programs was strong, providing developing countries with substantial amounts offoreign exchange. The relative size of the privatization program and the degree of openness to foreigners are important determinants of foreign direct investment. Each dollar in privatization revenue generates an additional 35 cents in new foreign direct investment inflows, and a 1 percent increase in foreign participation adds another 50 cents. In addition to the direct inflow of funds through the sale of assets, many developing countries also increasingly attracted foreign investment outside of their privatization programs. Privatization of infrastructure and the financial sector especially seem to have sent important signals to foreign investors, indicating an improved economic environment and possibly the eventual elimination of bottlenecks. Improved expectations about the profitability of investment projects render these countries more attractive to foreign investors.
Purification of an adenosine deaminase complexing protein from human plasma. (1979)

A protein which specifically complexes with adenosine deaminase (complexing protein) has been purified to homogeneity from human plasma. This protein was compared with complexing protein isolated from human kidney. The two proteins produce electrophoretically different forms of high molecular weight adenosine deaminase when combined with the Mr = 36,000 enzyme monomer from erythrocytes. This difference may, at least in part, be due to the greater sialic acid content of complexing protein from plasma. By other criteria, including amino acid composition, total carbohydrate content, and subunit structure, the two proteins are quite similar. In addition, plasma complexing protein shows complete cross-reactivity with anti-kidney complexing protein serum. These results suggest that plasma and kidney complexing proteins are products of the same gene.
A radiation center representation of antenna radiation patterns on a complex platform (2000)

A sparse model of the antenna radiation pattern on a complex platform is presented. This representation is based on a point radiator model that describes the radiation pattern by a collection of radiation centers on the platform. The methodology for obtaining the radiation center model is presented. It entails first generating the three-dimensional (3-D) antenna synthetic aperture radar (ASAR) imagery of the platform and then parameterizing the resulting image by a collection of point radiators via the CLEAN algorithm. It is shown that once such a representation is obtained, we can reconstruct and extrapolate antenna radiation patterns over frequencies and aspects with good fidelity, thus achieving high data compression ratio. Furthermore, it is shown that the resulting radiation center information can be used to pinpoint cause-and-effect in platform scattering and provide important guidelines for reducing platform effects.
Resveratrol and Clinical Trials: The Crossroad from In Vitro Studies to Human Evidence (2013)

Resveratrol (3,5,4'-trihydroxy-trans-stilbene) is a non-flavonoid polyphenol that may be present in a limited number of foodstuffs such as grapes and red wine. Resveratrol has been reported to exert a plethora of health benefits through many different mechanisms of action. This versatility and presence in the human diet have drawn the worldwide attention of many research groups over the past twenty years, which has resulted in a huge output of in vitro and animal (preclinical) studies. In line with this expectation, many resveratrol- based nutraceuticals are consumed all over the world with questionable clinical/scientific support. In fact, the confirmation of these benefits in humans through randomized clinical trials is still very limited. The vast majority of preclinical studies have been performed using assay conditions with a questionable extrapolation to humans, i.e. too high concentrations with potential safety concerns (adverse effects and drug interactions), short-term exposures, in vitro tests carried out with non-physiological metabolites and/or concentrations, etc. Unfortunately, all these hypothesis-generating studies have contributed to increased the number of 'potential' benefits and mechanisms of resveratrol but confirmation in humans is very limited. Therefore, there are many issues that should be addressed to avoid an apparent endless loop in resveratrol research. The so-called 'Resveratrol Paradox', i.e., low bioavailability but high bioactivity, is a conundrum not yet solved in which the final responsible actor (if any) for the exerted effects has not yet been unequivocally identified. It is becoming evident that resveratrol exerts cardioprotective benefits through the improvement of inflammatory markers, atherogenic profile, glucose metabolism and endothelial function. However, safety concerns remain unsolved regarding chronic consumption of high RES doses, specially in medicated people. This review will focus on the currently available evidence regarding resveratrol's effects on humans obtained from randomized clinical trials. In addition, we will provide a critical outlook for further research on this molecule that is evolving from a minor dietary compound to a possible multi-target therapeutic drug.
MO-CTTA-based Electronically Controlled Current- mode Square/Triangular Wave Generator (2010)

A new current-mode square/triangular wave generator based on MO-CTTAs (Multiple output current through transconductance amplifiers) is presented in this paper. The circuit description is very simple, its construction consists of 2 MO-CTTAs and 1 grounded capacitor without any external resistor. The output frequency and amplitude can be independently and electronically adjusted. With mentioned features, it is very suitable to realize in a monolithic chip. The PSPICE simulation results are depicted, and agree well with the theoretical anticipation. The maximum power consumption is approximately 3.27mW at ±1.5V power supply.
Differential absorption flattening optical effects are significant in the circular dichroism spectra of large membrane fragments (1987)

The circular dichroism spectra of membrane particles are distorted by effects of differential absorption flattening, which are a consequence of the nonrandom distribution of chromophores in these samples. We have shown that this phenomenon is not significant in small unilamellar vesicles with high lipid to protein ratios [Mao, D., & Wallace, B. A. (1984) Biochemistry 23, 2667-2673]. It has recently been claimed [Glaeser, R. M., & Jap, B. K. (1985) Biochemistry 24, 6398-6401] that absorption flattening effects are also inconsequential in large membrane fragments with high protein concentrations, such as purple membrane sheets. This paper will demonstrate that absorption flattening is significant in these samples and that it causes substantial distortion of the calculated protein secondary structures derived from the uncorrected circular dichroism data.
Synthesis of the bicyclic core of tagetitoxin (2006)

A synthesis of the 9-oxa-3-thiabicyclo[3.3.1]nonane ring system, which constitutes the core of the RNA polymerase inhibitor tagetitoxin, has been achieved through cyclisation of a thiol onto an electrophilic ketone.
Narrow or Monodisperse, Highly Cross-Linked, and “Living” Polymer Microspheres by Atom Transfer Radical Precipitation Polymerization (2011)

A facile, general, and efficient one-pot approach to obtaining narrow or monodisperse, highly cross-linked, surface-functionalized, and “living” polymer microspheres with uniformly cross-linked structures by atom transfer radical precipitation polymerization (ATRPP) is described for the first time. The simple introduction of atom transfer radical polymerization (ATRP) mechanism into precipitation polymerization system allows the direct generation of uniformly cross-linked “living” polymer microspheres with their number-average diameters ranging from 0.73 to 3.25 μm and their polydispersity indices being typically lower than 1.01. The polymerization parameters (including stirring rate, monomer loading, initiator and catalyst concentrations, molar ratio of cross-linker to monovinyl functional comonomer, and polymerization scale and time) have proven to show significant influence on the morphologies of the resulting polymer microspheres, which makes it very convenient to control the particle sizes by easily tuning the reaction conditions. The general applicability of ATRPP was demonstrated by synthesizing a series of uniform functional copolymer microspheres with different incorporated functional comonomers (i.e, 4-vinylpyridine, acrylamide, and 2-hydroxyethyl methacrylate). Moreover, the “livingness” of the resulting polymer microspheres was confirmed by their direct grafting of hydrophilic polymer brushes via surface-initiated ATRP under mild reaction conditions. Furthermore, a “grafting from” particle growth mechanism is proposed for ATRPP, which is considerably different from the “grafting to” particle growth mechanism in the traditional precipitation polymerization.
Multidetector CT features of pulmonary focal ground-glass opacity: differences between benign and malignant (2012)

An fGGO with lobulation, a well-defined but coarse interface and pleural indentation gives a greater than average likelihood of being malignant.
Standing Up to Osteoporosis (1997)

Educational Objectives 1. To provide basic information about osteoporosis, including risk factors, diagnostic testing, treatment, and prevention. 2. To get you to help us spread the word that osteoporosis can be diagnosed and treated, and that there are things you can do to decrease your future risk for developing osteoporosis.
In Training (1994)

Journal Article In Training Get access O. F. W. James O. F. W. James Department of Medicine (Geriatrics), Floor 4, William Leech Building, The Medical SchoolFramlington Place, Newcastle upon Tyne NE2 4HH Search for other works by this author on: Oxford Academic PubMed Google Scholar Age and Ageing, Volume 23, Issue suppl_3, 1994, Pages S43–S45, https://doi.org/10.1093/ageing/23.suppl_3.S43 Published: 01 September 1994
Erythrocyte autoantibodies, autoimmune haemolysis, and myelodysplastic syndromes. (1989)

Immunohaematological investigations were carried out in 46 patients with erythrocyte autoantibodies associated with myelodysplastic syndromes. Eight patients had refractory anaemia, 17 refractory anaemia with ring sideroblasts, 11 refractory anaemia with excess of blasts, four chronic myelomonocytic leukaemia, five refractory anaemia with excess of blasts in transformation and one could not be classified. Standard agglutination direct antiglobulin tests showed that the red cells were most often coated with IgG and C3d, though increased amounts of IgM or IgA were also found in 15 of 35 cases (43%) when the more sensitive enzyme linked method was used. The IgG antibodies were predominantly of IgG1 subclass. Clinically important autoimmune haemolysis occurred in 15 patients, and was of "warm", "cold," and "mixed" types in seven, four, and four cases, respectively: it is important to recognise its presence in view of the good response to treatment. The increased incidence of erythrocyte autoantibodies in myelodysplastic syndromes is thought to be one manifestation of disturbed immune homeostasis.
In vivo optical imaging in arthritis--an enlightening future? (2010)

In vivo molecular optical imaging has significant potential to delineate and measure, at the macroscopic level, in vivo biological processes that are occurring at the cellular and molecular level. Optical imaging has already been developed for in vitro and ex vivo applications in molecular and cellular biology (e.g. fluorescence confocal microscopy), but is still at an early stage of development as a whole-animal in vivo imaging technique. Both sensitivity and spatial resolution remain incompletely defined. Rapid advances in hardware technology and highly innovative reporter probes and dyes will be expected to deliver significant insight into perturbations of molecular pathways that occur in disease, ultimately with the potential of translating into future molecular imaging techniques for patients with arthritis. This review will focus on currently available technologies for live in vivo animal optical imaging, including fluorescence reflectance imaging, potential novel tomographic techniques, bioluminescence reporter technology and potential novel labelling techniques, highlighting in particular the potential application of in vivo fluorescence imaging in arthritis.
PU text classification enhanced by term frequency–inverse document frequency‐improved weighting (2013)

SUMMARY Term frequency–inverse document frequency (TF–IDF), one of the most popular feature (also called term or word) weighting methods used to describe documents in the vector space model and the applications related to text mining and information retrieval, can effectively reflect the importance of the term in the collection of documents, in which all documents play the same roles. But, TF–IDF does not take into account the difference of term IDF weighting if the documents play different roles in the collection of documents, such as positive and negative training set in text classification. In view of the aforementioned text, this paper presents a novel TF–IDF‐improved feature weighting approach, which reflects the importance of the term in the positive and the negative training examples, respectively. We also build a weighted voting classifier by iteratively applying the support vector machine algorithm and implement one‐class support vector machine and Positive Example Based Learning methods used for comparison. During classifying, an improved 1‐DNF algorithm, called 1‐DNFC, is also adopted, aiming at identifying more reliable negative documents from the unlabeled examples set. The experimental results show that the performance of term frequency inverse positive–negative document frequency‐based classifier outperforms that of TF–IDF‐based one, and the performance of weighted voting classifier also exceeds that of one‐class support vector machine‐based classifier and Positive Example Based Learning‐based classifier. Copyright © 2013 John Wiley & Sons, Ltd.
Push- and pull-based epidemic spreading in networks (2012)

Understanding the dynamics of computer virus (malware, worm) in cyberspace is an important problem that has attracted a fair amount of attention. Early investigations for this purpose adapted biological epidemic models, and thus inherited the so-called homogeneity assumption that each node is equally connected to others. Later studies relaxed this often unrealistic homogeneity assumption, but still focused on certain power-law networks. Recently, researchers investigated epidemic models in arbitrary networks (i.e., no restrictions on network topology). However, all these models only capture push-based infection, namely that an infectious node always actively attempts to infect its neighboring nodes. Very recently, the concept of pull-based infection was introduced but was not treated rigorously. Along this line of research, the present article investigates push- and pull-based epidemic spreading dynamics in arbitrary networks, using a nonlinear dynamical systems approach. The article advances the state-of-the-art as follows: (1) It presents a more general and powerful sufficient condition (also known as epidemic threshold in the literature) under which the spreading will become stable. (2) It gives both upper and lower bounds on the global mean infection rate, regardless of the stability of the spreading. (3) It offers insights into, among other things, the estimation of the global mean infection rate through localized monitoring of a small constant number of nodes, without knowing the values of the parameters.
Receptor-mediated Endocytosis Is Not Required for Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL)-induced Apoptosis (2007)

Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) is selectively toxic to tumor compared with normal cells. Other members of the TNF family of death ligands (TNF, CD95L) engage their respective receptors (TNF-R1 and CD95), resulting in internalization of receptor and ligand and recruitment of adaptor proteins to the caspase activation platform known as the death-inducing signaling complex (DISC). Recently, TNF-R1 and CD95 have been shown to induce apoptosis with an absolute requirement for internalization of their corresponding receptors in the formation of a DISC. We show that TRAIL and its receptors are rapidly endocytosed in a time- and concentration-dependent manner. Blockade of receptor internalization with hyperosmotic sucrose did not inhibit TRAIL-induced apoptosis but, rather, amplified the apoptotic signaling of TRAIL. Plate-bound and soluble TRAIL induced similar levels of apoptosis. Together these results suggest that neither ligand nor receptor internalization is required for TRAIL-induced apoptosis. Internalization of TRAIL is mediated primarily by clathrin-dependent endocytosis and also by clathrin-independent pathways. Inhibition of clathrin-dependent internalization by overexpression of dominant negative forms of dynamin or AP180 did not inhibit TRAIL-induced apoptosis. Consistent with the finding that neither internalization of TRAIL nor its receptors is required for transmission of its apoptotic signal, recruitment of FADD (Fas-associated death domain) and procaspase-8 to form the TRAIL-associated DISC occurred at 4 degrees C, independent of endocytosis. Our findings demonstrate that TRAIL and TRAIL receptor 1/2, unlike TNF-TNF-R1 or CD95L-CD95, do not require internalization for formation of the DISC, activation of caspase-8, or transmission of an apoptotic signal in BJAB type I cells.
[Device for treatment of wounds and abdominal cavity]. (1997)

An original device for the wound and abdominal cavity pretreatment has been proposed. It has the following advantages: high rate of effectiveness in wound pretreatment, simplicity in usage, economical use of a washing solution. The device may be used in clinical practice for the wound and abdominal cavity cleansing.
SUPER‐CERAMIC BUILDING MEMBERS* (1937)

A bstract Ceramic masonry units, properly formed of suitable raw materials and well fired, are characterized by high compressive strengths. When assembled into building members their usefulness ordinarily is limited by the weakness of mortar joints; even the inclusion of reinforcing in a mortar joint fails to develop the potentialities of the high compressive strengths and stiffness available in the units. Prestressing does, in effect, change part of the excess compressive strength into tensile strength, permitting much better application of materials, whether in beams or in columns. In the former, the underside is placed initially under compression while, even in columns, suitable prestressing reduces the buckling tendency of slender members which otherwise would cause failure far short of the compressive‐strength potentialities. Analysis of the prestressing and loading operations is secured with the aid of celluloid models and polarized light.
Presentation of Salmonella antigens by dendritic cells (2001)

The study demonstrates that besides the "classical" variables of bum scores as age, TBSAB and IHT other variables such as sex, AA, NA and preexisting diseases have significant influence on the outcome. These variables especially gain important predictive value in patients with a medium risk of mortality.
A phantom-based calibration method for digital x-ray tomosynthesis (2012)

For the specific experimental conditions utilized in this study, the phantom-based calibration method effectively reduced reconstruction artifacts for the prototype investigated in this study. The calibration method holds potential to benefit other tomosynthesis applications.
Case study on exceptions (1995)

Discusses exceptions in office work and the link between rules and exceptions in office information systems. After describing the nature of exceptions, examines their effect on rules. Provides a case study of a factory purchasing process, including unmatched invoices, costs, classification and strategic changes.