gebhart/patrepeval huggingface dataset:
Word Neighbours and Onalosis (2002)

This article is a partial update of my "Statistics of Word Neighbours" in the November 1997 Word Ways, and provides the facts laying behind the findings in the recent series (August 2000 through May 2001) of articles on word ladders. Two words are neighbours if they differ in a single letter. In this article, each such word is credited as having a neighbour, i.e. the link between them in counted twice (please refer to the earlier article for prior work and more information). The following table updates various parts of the article.
WORKS OF ART AND THEIR AVAILABILITY-FOR-USE (1971)

WORKS OF ART AND THEIR AVAILABILITY-FOR-USE Get access Peter Jones Peter Jones Search for other works by this author on: Oxford Academic Google Scholar The British Journal of Aesthetics, Volume 11, Issue 2, SPRING 1971, Pages 115–122, https://doi.org/10.1093/bjaesthetics/11.2.115 Published: 01 February 1971
When intracellular pathogens invade the frontiers of cell biology and immunology. (1997)

Cellular microbiology has recently been described as a new discipline emerging at the interface between cell biology and microbiology (Cossart et al., 1996). Many microbial pathogens can enter eukaryotic cells and live intracellularly either inside vacuoles or in the cytoplasm. The different steps during the invasion process are on the way of being dissected at the molecular level revealing new insights in basic cellular functions. Indeed, bacterial pathogenesis can help us to better understand the dynamics of cell cytoskeleton, intracellular membrane traffic and signal transduction events. The recent advancements in the field of microbial pathogenesis are creating a new cross-talk between cell biologists, microbiologists and immunologists. In this review, the different strategies used by several pathogens are presented and the mechanisms elaborated by host cells from the immune system to eliminate the parasites discussed.
Prolog as a simulation language (1984)

Prolog is a rather new language and is very different from traditional languages. Prolog is favored by the Japanese for their Fifth Generation Computer Systems. The acronym PROLOG is derived from PROgramming in LOGic and emphasizes the derivation of the language from predicate logic. Prolog can be considered as a general purpose very high level language, best suited for general symbol manipulation, intelligent and flexible database handling or problems, where some kind of search is required. Examples of application areas are computer aided design, database and “knowledge-base” management, natural language processing and rapid prototyping.It is the purpose of this paper to demonstrate, how Prolog can be used as a tool in a simulation project.The paper consists of two parts: a survey of the language Prolog and a description of T-Prolog, a Prolog based simulation language, using a process interaction approach.
Header encryption of IEEE802.15.4 (2016)

In this paper, we mainly focus on the security of 802.15.4 MAC (Media Access Control) which used in Zigbee technology. Today, 802.15.4 Medium Access Control (MAC) is used in personal area networks, for example industrial automation, medical, home automation. However, encryption on MAC data payload have been introduced, but Medium Access Control (MAC) header is still non-encrypted. Authentication of MAC header is certainly done with the use of Data Integrity by giving Message Authentication Code or Message Integrity Code (MIC). Medium Access Control (MAC) header frame has three fields: frame control, addresses and auxiliary security. Among all of these fields of MAC header which includes frame control, sequence number, source and destination addresses and auxiliary security header (ASH) must be encrypted to secure it against some attacks like ACK attack, replay protection attack, snooping attack, denial of service attack, CTS replay, RTS replay. Auxiliary security header have the details about the security of data payload which must not be known to intruders. Our aim for securing it is multi level security. This header field has a total of 40 bytes. For encryption of these 40 bytes of Medium Access Control (MAC) header, we have used Advance Encryption Standard (AES) algorithm, which creates best confusion and diffusion. Advance Encryption Standard algorithm has three types of frame structure: 128 bits, 192 bits, 256 bits. To encrypt these 40 bytes of Medium Access Control (MAC) header we have used two Advance Encryption Standard (AES) algorithms of 192 bits and 128 bits which both are working parallel together.
Exploring the roles of PALB2 at the crossroads of DNA repair and cancer (2014)

Volume 460 (2014), pp. 331–342In the published article, the incorrect definition for BRCA2 was introduced during the production process as breast cancer early-onset 1. This appears in the Abstract and Introduction. The correct definition should be breast cancer early-onset 2 in both places.The following sentence appears on page 337: In summary, nine truncating mutations of PALB2, eight recurrent notably in breast cancer, have been found so far in ovarian cancer cases including c.172_175delTTGT (Prokofyeva et al. [91]), c.509_510delGA (Dansonka-Mieskowska et al. [67]), c.757_758delCT, c.1050delAACA (Walsh et al. [88]), c.2323C>T (Tischkowitz et al. [79]). The examples of mutations should be omitted, with the full list in Table 1. The correct sentence should read: In summary, nine truncating mutations of PALB2, eight recurrent notably in breast cancer, have been found so far in ovarian cancer cases.
Tandem mass spectrometry: dissociation of ions by collisional activation (2000)

This review presents a brief historical introduction to the development of tandem mass spectrometry and its principal applications. It is placed in the context of the general principles underlying mass spectrometry, particularly the relationships between internal energy and fragmentation kinetics. The center-of-mass framework is presented as a convenient means of applying conservation of momentum to the energy transfer problem in tandem mass spectrometry as a means of deducing energy transfer in the collisional activation step and kinetic energy release as activated ions dissociate into fragment ions and neutrals. The principles of molecular beam methods are summarized and illustrative examples are given for which definitive information on reaction dynamics is available. The importance of scattering-very little appreciated in early discussions of tandem mass spectrometry-is shown to be the natural consequence of impulsive collisions, which appears to be a general mechanism for energy exchange in collisional activation. It is shown that the average energy transferred in single collisions is much less than the theoretical maximum given by the center-of-mass collision energy and the Massey criterion is presented as a simplistic rationale for understanding the essentially exponential decline in the energy transfer function above and below the relative velocity at which the probability for energy transfer is maximized. The issues of energy transfer in collisions of large molecular ions with low-mass neutrals are reviewed and a general description of energy transfer in multiple collisions is presented. It is shown that the center-of-mass and Massey criterion limitations are pragmatically overcome by multiple collision activation in ion traps. Surface-induced dissociation is presented as a viable alternative to multiple collision activation which is especially attractive for activation of large molecular ions. Finally, a few of the emerging dynamics principles governing energy transfer and dissociation of peptides are summarized. Copyright 2000 John Wiley & Sons, Ltd.
Redox chemistry of cobalamin and iron‐sulfur cofactors in the tetrachloroethene reductase of <i>Dehalobacter restrictus</i> (1997)

Respiration of Dehalobacter restrictus is based on reductive dechlorination of tetrachloroethene. The terminal component of the respiratory chain is the membrane-bound tetrachloroethene reductase. The metal prosthetic groups of the purified enzyme have been studied by optical and EPR spectroscopy. The 60-kDa monomer contains one cobalamin with Em(Co[1+/2+]) = -350 mV and Em(Co[2+/3+]) > 150 mV and two electron-transferring [4Fe-4S](2+;1+) clusters with rather low redox potentials of Em approximately -480 mV. The cob(II)alamin is present in the base-off configuration. A completely reduced enzyme sample reacted very rapidly with tetrachloroethene yielding base-off cob(II)alamin rather than trichlorovinyl-cob(III)alamin.
Propylene Oxide as Sterilizing Agent (1974)

Liquid propylene oxide added to a variety of disinfectant solutions resulted in a significant reduction of the bacterial spore content of these solutions.
Comparing Performances of Markov Blanket and Tree Augmented Naïve-Bayes on the IRIS Dataset (2014)

This research investigates the performances of the Markov Blanket (MB) and Tree Augmented Naïve-Bayes Network (TAN) of the Bayesian Network structure of the IRIS dataset. For evaluation purposes, the performances of the TAN, and MB classifiers were measured using statistical indices. Experimental results strongly suggested that the TAN is better than MB on training dataset and vise vasa in the test dataset. In the other hand, time computational complexity of both the classifiers was found to be equal. The result obtained in this research is of significance to researchers intending to use Bayesian Network to create a classifier for enhancing the performance of biometrics systems
THERMAL-AWARE SCHEDULING IN ENVIRONMENTALLY COUPLED CYBER-PHYSICAL DISTRIBUTED SYSTEMS (2008)

This dissertation work deals with a special type of distributed systems which are referred to as Envi-ronmentally Coupled Cyber-Physical Distributed System (ECCPDS). An ECCPDS is a distributed system in which the operation of the distributed system has a direct physical impact on its environment and vice versa. The deployment and operation of such distributed systems may have thermal, electrical, biological, acoustic, or mechanical interference on the surrounding environment. This work mainly focuses on thermal interference because temperature rising is the most critical issue for electronic devices, and thermal interference is the most direct impact applied on the environment and distributed nodes themselves. This work explores the possibility of minimizing interference through the network and system operation approach, instead of the individual design approach. The work focuses on two exemplar applications: thermal-aware in-vivo biosensor network design and thermal management of data center. These two applications are vastly different and help to validate general applicability of the proposed approaches and methodology. Numerical simulations show that the approaches can reduce the temperature rise through heuristic scheduling algorithms which consider some extra design factors such as locations, job history, cross interference, etc. For thermal-aware scheduling of biosensor
Joint optimization of time and frequency synchronization based on polynomial sequences for OFDM systems (2009)

在直角的频率部门 multiplexing (OFDM ) ，系统，时间和频率同步是为保证 OFDM 副载波的 orthogonality 的二个批评元素。与在序言的序列设计的伪噪音(PN ) 的雇用，通常，序言信息充分没在两标志预定被利用偏移量获得和搬运人频率偏移量评价。在这篇文章，一个新同步算法为联合优化时间和频率同步被建议。这个算法把多项式序列用作同步序言而不是 PN 序列。理论分析和模拟结果显示建议算法比另外的存在方法更精确、可靠。
Development of Branched Poly(5-Amino-1-pentanol-<i>co</i>-1,4-butanediol Diacrylate) with High Gene Transfection Potency Across Diverse Cell Types (2016)

One of the most significant challenges in the development of polymer materials for gene delivery is to understand how topological structure influences their transfection properties. Poly(5-amino-1-pentanol-co-1,4-butanediol diacrylate) (C32) has proven to be the top-performing gene delivery vector developed to date. Here, we report the development of branched poly(5-amino-1-pentanol-co-1,4-butanediol diacrylate) (HC32) as a novel gene vector and elucidate how the topological structure affects gene delivery properties. We found that the branched structure has a big impact on gene transfection efficiency resulting in a superior transfection efficiency of HC32 in comparison to C32 with a linear structure. Mechanistic investigations illustrated that the branched structure enhanced DNA binding, leading to the formation of toroidal polyplexes with smaller size and higher cationic charge. Importantly, the branched structure offers HC32 a larger chemical space for terminal functionalization (e.g., guanidinylation) to further enhance the transfection. Moreover, the optimized HC32 is capable of transfecting a diverse range of cell types including cells that are known to be difficult to transfect such as stem cells and astrocytes with high efficiency. Our study provides a new insight into the rational design of poly(β-amino ester) (PAE) based polymers for gene delivery.
<i>Amborella trichopoda</i> (Amborellaceae) and the evolutionary developmental origins of the angiosperm progamic phase (2008)

A remarkable number of the defining features of flowering plants are expressed during the life history stage between pollination and fertilization. Hand pollinations of Amborella trichopoda (Amborellaceae) in New Caledonia show that when the stigma is first receptive, the female gametophyte is near maturity. Pollen germinates within 2 h, and pollen tubes with callose walls and plugs grow entirely within secretions from stigma to stylar canal and ovarian cavity. Pollen tubes enter the micropyle within 14 h, and double fertilization occurs within 24 h. Hundreds of pollen tubes grow to the base of the stigma, but few enter the open stylar canal. New data from Amborella , combined with a review of fertilization biology of other early‐divergent angiosperms, show that an evolutionary transition from slow reproduction to rapid reproduction occurred early in angiosperm history. I identify increased pollen tube growth rates within novel secretory carpel tissues as the primary mechanism for such a shift. The opportunity for prezygotic selection through interactions with the stigma is also an important innovation. Pollen tube wall construction and substantial modifications of the ovule and its associated structures greatly facilitated a new kind of reproductive biology.
Low field driven latching-type Bi3Fe5O12∕Gd3Ga5O12 magneto-optical display (2006)

Series of heteroepitaxial all-garnet magneto-optical (MO) Bi3Fe5O12n∕Gd3Ga5O12m (BIGn∕GGGm, n=1, 2, 3, 4, 5 and m=1 and 2 are the numbers of unit cells) nanostructured multilayers have been sintered by pulsed laser deposition technique. Processing parameters and structure of grown films have been optimized to obtain perpendicular magnetic anisotropy and square hysteresis loop with low coercive and saturation magnetic fields. Regular alternating of lattice mismatched BIG and GGG atomic layers inhibited nucleation of misfit dislocations; thus a long range coherent compressive strain was preserved through the whole thickness of BIGn∕GGGm multilayer stack. 2.5μm thick BIG3∕GGG2 sample (1200 BIG and 800 GGG unit cells) at λ=678nm shows MO Faraday rotation ΘF=±1.4°, transmittance of 82%, attenuation α=3400dB∕cm, squareness of magnetization loop (remnant-to-saturation magnetizations ratio) as high as 92%, and saturation and coercive fields as low as 56 and 25Oe, respectively. MO remanence (latching capability) enables application of nanostructured garnet as a magnetic relief replicator/visualizer and as a material for low power consuming displays.
ChemInform Abstract: TETRAHYDRO‐ UND DIHYDRO‐BETA‐CARBOLINE AUS TRYPTOPHAN UND 5‐METHOXY‐TRYPTOPHAN (1973)

Abstract Die Hydrochloride der nach bekannten Methoden dargestellten Tryptamine (Ia) bzw. (Ib) cyclisieren sich in wäßriger Lösung mit Acetaldehyd (II) zu den Methylcarbolinen (IIIa) bzw. (IIIb).
Secure Method for De-Identifying and Anonymizing Large Panel Datasets (2019)

Government agencies, as well as private companies, may need to share private information with third party organizations for various reasons. There exist legitimate concerns about disclosing the information of individuals, sensitive details of agencies and organizations, and other private information. Consequently, information shared with external parties may be redacted to hide confidential information about individuals and companies while providing essential data required by third parties in order to perform their duties. This paper presents a method to de-identify and anonymize large-scale panel data from an organization. The method can handle a variety of data types, and it is scalable to datasets of any size. The challenge of de-identification and anonymization a large-scale and diverse dataset is to protect individual identities and retain useful data in the presence of unstructured field data and unpredictable frequency distributions. This is addressed by analyzing the dataset and applying a filtering and aggregation method. This is accompanied by a streamlined implementation and post-validation process, which ensures the security of the organization's data, and the computational efficiency of the approach when handling large-scale panel data sets.
Identification of a region of UDP-galactose:N-acetylglucosamine beta 4-galactosyltransferase involved in UDP-galactose binding by differential labeling. (1990)

The location of regions in the primary structure of UDP-galactose:N-acetylglucosamine beta 4-galactosyl-transferase (GT) that are involved in binding UDP-galactose has been investigated by differential chemical modification with two different reagents in the presence and absence of UDP-galactose. Treatment with periodate-cleaved UDP and NaCNBH3 resulted in a loss of 80% of GT activity, which was largely prevented by UDP-galactose. Stoichiometry of labeling and peptide maps of the modified enzyme samples indicated partial labeling at many sites. A major site of reaction in the absence of UDP-galactose that was essentially unmodified in its presence was found to correspond to Lys341 in the cDNA sequence of GT. As a second approach, the reactivities of the amino groups of GT were compared in the presence and absence of saturating levels of UDP-galactose by trace acetylation with [3H]acetic anhydride. UDP-galactose binding was found to perturb the reactivities of a number of lysines in the C-terminal region of GT, the most pronounced effect being a reduction in the reactivity of Lys351. The two procedures thus identified a region between residues 341 and 351 as being associated with UDP-galactose binding. This region overlaps a small section in the sequence of GT that was previously noted to be similar to part of bovine alpha-1,3-galactosyltransferase (Joziasse, D. H., Shaper, J. H., Van den Eijnden, D. H., Van Tunen, A. J., and Shaper, N. L. (1989) J. Biol. Chem. 264, 14290-14297). Sequence comparisons indicate that extended regions at the C terminus of each enzyme encompassing this area may represent homologous UDP-galactose-binding domains.
Free-radical-induced formation of an 8,5′-cyclo-2′-deoxyguanosine moiety in deoxyribonucleic acid (1986)

Isolation and identification of a novel .OH-induced product, namely an 8,5'-cyclo-2'-deoxyguanosine moiety, in DNA and 2'-deoxyguanosine are described. .OH radicals were generated in dilute aqueous solutions by gamma-irradiation. Analyses of 2'-deoxyguanosine and enzymic hydrolysates of DNA by gas chromatography-mass spectrometry (g.c.-m.s.) after trimethylsilylation showed the presence of 8,5-cyclo-2'-deoxyguanosine on the basis of its fragment ions. This product was isolated by h.p.l.c. Its u.v. and n.m.r. spectra taken were in agreement with the structure suggested by its mass spectrum. Exact masses of the typical ions from the mass spectrum of the trimethylsilyl derivative of this product were measured by high-resolution m.s. The values found were in excellent agreement with the theoretical mass derived from the suggested fragmentation patterns. Both (5'R)- and (5'S)-epimers of 8,5'-cyclo-2'-deoxyguanosine were observed. These two diastereomers were separated from each other by g.c. as well as by h.p.l.c. The assignment of the epimers was accomplished on the basis of the n.m.r. data. The formation of 8,5'-cyclo-2'-deoxyguanosine was suppressed by the presence of O2 in the solutions. The use of g.c.-m.s. with the selected-ion monitoring technique facilitated the detection of 8,5'-cyclo-2'-deoxyguanosine in DNA at radiation doses as low as 1 Gy. Its mechanism of formation probably involves hydrogen atom abstraction by .OH radicals from the C-5' of the 2'-deoxyguanosine moiety followed by intramolecular cyclization with the formation of a covalent bond between the C-5' and C-8 and subsequent oxidation of the resulting N-7-centred radical.
CD8 T cell responses to ECTV-WT and ECTV-IFN-γbp<sup>Δ</sup>. (2015)

<p>Mice (n = 5–10/group) were infected with ECTV-WT or ECTV-IFN-γbp and sacrificed 7 days later to measure splenic CTL activity. Shown is % specific lysis of <sup>51</sup>Cr-labelled, ECTV-infected P815 target cells by splenocytes from (A) ECTV-WT- or (B) ECTV-IFN-γbp<sup>Δ</sup>-infected WT and GKO mice. (C) Percent specific lysis of targets by splenocytes at 75:1 effector-to-target ratio. Two-way ANOVA followed by Fisher’s LSD test for significance was used for statistical analysis: (i) CTL response to ECTV-WT vs. ECTV-IFN-γbp<sup>Δ</sup> in IL-13<sup>−/−</sup> (p < 0.0001) and STAT-6<sup>−/−</sup> (p < 0.0001) (ii) CTL response to ECTV-WT in WT vs IL-4<sup>−/−</sup> (p = 0.0083), vs STAT-6<sup>−/−</sup> (p = 0.0003), vs IL-13<sup>−/−</sup> (p = 0.0001), vs IL-13<sup>−/−</sup>/IL-4Rα<sup>−/−</sup> (p = 0.0037) mice; (iii) CTL response to ECTV-IFN-γbp in WT vs STAT-6<sup>−/−</sup> (p = 0.0002); vs IL-13<sup>−/−</sup> (p = 0.0478); vs IL-4Rα<sup>−/−</sup> (p = 0.0174) and IL-13<sup>−/−</sup>/IL-4Rα<sup>−/−</sup> (p = 0.000046) mice. ****, p<0.0001. (D—F) Spleen cells from mice infected mice were re-stimulated for 5 h with ECTV-infected P815 cells or H-2<sup>d</sup> 8 T cell peptide determinants prior to intracellular IFN-γ staining followed by flow cytometry. Data shown are means of absolute numbers of ECTV-specific IFN-γ<sup>+</sup> 8 T cells in spleens of ECTV-WT- vs. ECTV-IFN-γbp<sup><b>Δ</b></sup>-infected mice (D) and determinant-specific IFN-γ<sup>+</sup> 8 T cells following infection with ECTV-WT (E) or ECTV-IFN-γbp (F) viruses. Two-way ANOVA followed by Fisher’s LSD test for significance was used for statistical analysis. For panels D, E and F, IFN-γ<sup>+</sup> 8 T cell numbers in WT mice were significantly higher (p<0.0001) than numbers in all GKO strains. Data shown for D-F are representative of one of three independent experiments with similar results. *, <i>p</i>< 0.05; **, <i>p</i> < 0.01; ***, <i>p</i> < 0.0001.</p>
Activation of the Abelson tyrosine kinase activity is associated with suppression of apoptosis in hemopoietic cells. (1993)

A chromosomal translocation uniquely associated with chronic myeloid leukemia leads to the formation of a chimeric gene, bcr-abl, on the Philadelphia chromosome. The BRC-ABL protein displays an uncontrolled tyrosine kinase activity similar to that seen with the transforming oncogene of the Abelson murine leukemia (ABL) virus (v-abl). An interleukin 3 dependent cell line, IC.DP, has been transfected with a gene encoding a temperature sensitive v-ABL. In the absence of interleukin 3 at the restrictive temperature for ABL tyrosine kinase activity IC.DP cells died via apoptosis. At the permissive temperature ABL tyrosine kinase activity promoted IC.DP cell survival but not proliferation. ABL therefore can specifically suppress apoptosis.
Principles of Organ Transplantation (1989)

Principles of organ transplantation , Principles of organ transplantation , کتابخانه دیجیتالی دانشگاه علوم پزشکی و خدمات درمانی شهید بهشتی
Immunology of the Gastrointestinal Tract and Liver (1988)

Journal of Clinical Gastroenterology gathers the world's latest, most relevant clinical studies and reviews, case reports, and technical expertise in a single source. Regular features include cutting-edge, peer-reviewed articles and clinical reviews that put the latest research and development into the context of your practice. Also included are biographies, focused organ reviews, practice management, and therapeutic recommendations.