gebhart/patrepeval huggingface dataset:
Leydig Cell Aging: Steroidogenic Acute Regulatory Protein (StAR) and Cholesterol Side‐Chain Cleavage Enzyme (2001)

Primary points of control in steroidogenesis are the transport of cholesterol from intracellular stores to the inner mitochondrial membrane, and the subsequent conversion of cholesterol to pregnenolone by the cholesterol side-chain cleavage enzyme (P450scc). Testosterone production has been shown to decline in Brown Norway rat Leydig cells as the rats age. To better understand the mechanism by which aging Leydig cells lose steroidogenic function, we examined the effect of aging on steroidogenic acute regulatory protein (StAR), an important Leydig cell cholesterol transfer protein, and on P450scc. Leydig cells isolated from middle-aged (14 months) and old (24 months) rats produced significantly less testosterone than cells from young (4 months) rats. StAR mRNA (1.7 kilobase [kb]) was significantly reduced in Leydig cells from middle-aged and old rats, by 26% and 52%, respectively. Significant reductions also were seen in the steady-state levels of mRNA for P450scc, of 29% and 50%, respectively. Western blots revealed significant reductions in StAR protein, by 47% and 74%, respectively, and in P450scc protein, by 38% and 54%, respectively. In response to LH stimulation in vitro, testosterone production by Leydig cells in young, middle-aged, and old rats increased by 30-, 40-, and 33-fold, respectively, although the amounts of testosterone produced by the young cells significantly exceeded that produced by the middle-aged and old cells. StAR protein also increased in response to LH by 1.4- , 3-, and 11-fold, respectively, whereas P450scc protein remained unchanged. These results are consistent with the conclusion that compromise of StAR-mediated cholesterol transport may play a key role in age-related reductions in Leydig cell steroidogenesis. However, because P450scc is reduced in old Leydig cells, the reaction catalyzed by this enzyme would be rate-limiting under circumstances in which saturating amounts of cholesterol entered the mitochondria.
Statistically Based Decompression Tables. 3. Comparative Risk Using U.S. Navy, British, and Canadian Standard Air Schedules. (1986)

The first report of this series used probabilistic models to analyze the decompression safety of approximately 2000 single compressed air drives. The most successful model used in Report II generated new equal-risk decompression tables and was applied here to estimate the risk of bends using any of the current U.S. Navy, (U.K.) Royal Navy, and Canadian Forces standard air decompression tables. The range of risk went from less than 1% for short duration dives at most depths, to over 20% for exceptionally long exposures. The new Canadian schedules are generally safest because of their long decompression times, followed by British and then American schedules. Keywords: Diving; Decompression sickness; Saturation diving; Mathematical modeling; Likelihood estimation; Inert gas kinetics.
Comparison of sandwich and fingers-crossing type WO<sub>3</sub>/BiVO<sub>4</sub> multilayer heterojunctions for photoelectrochemical water oxidation (2016)

Sandwich and fingers-crossing type WO<sub>3</sub>/BiVO<sub>4</sub> multilayer heterojunctions were fabricated to investigate the influence of the junction structure on their photoelectrochemical performances.
A semimicro thermomechanical technique for characterizing polymeric materials: Torsional braid analysis (1974)

Abstract An overview of a nondestructive semimicro mechanical technique–pioneered, developed, and exploited by the author–which is used for characterizing phase transitions and transformations in polymeric materials is presented. Particular attention is given to literature published since January, 1972, which pertains to advances in automation, data acquisition and processing, and application to polymeric systems. The instrument has been consolidated as a powerful and convenient mechanical spectrometer in this short period.
Spin transfer nano-oscillators (2013)

The use of spin transfer nano-oscillators (STNOs) to generate microwave signals in nanoscale devices has aroused tremendous and continuous research interest in recent years. Their key features are frequency tunability, nanoscale size, broad working temperature, and easy integration with standard silicon technology. In this feature article, we give an overview of recent developments and breakthroughs in the materials, geometry design and properties of STNOs. We focus in more depth on our latest advances in STNOs with perpendicular anisotropy, showing a way to improve the output power of STNO towards the μW range. Challenges and perspectives of the STNOs that might be productive topics for future research are also briefly discussed.
In vitro assay for erythropoietin: erythroid colony formation in methyl cellulose used for the measurement of erythropoietin in plasma (1979)

Erythroid colony formation in methyl cellulose has been used for the measurement of erythropoietin in plasma. Livers from newborn mice less than 24 hr old were found to provide convenient target cells. Newborn mouse liver contains a substantial number of erythroid colony-forming cells (CFU-e) that have a high sensitivity to erythropoietin, the dose-- response curve for erythropoietin reaching a plateau at 50 mU/ml. As little as 0.5 m/ml of the hormone is detectable. Removal of cells that adhered to glass prior to culturing doubled the number of colonies formed in the presence of erythropoietin. Addition of untreated plasmas that showed high erythropoietin titers in the exhypoxic polycythemic mice assay gave variable results. Some of the plasmas stimulated colony formation actively and in a linear fashion. However, the majority of the plasmas were toxic to the cultures. Dialyzing the plasmas for 3 days against distilled water effectively removed the toxicity. Results obtained with the method are in good agreement with the values found using the exhypoxic polycythemic mice assay.
Design and Simulation Research on the Energy Absorption Fender on the Head Car of a High Speed Train (2011)

With the design thought of the collision resistant system,the design plans with application of the new type energy absorption structure and filler material are put forward,and the design plans are compared through the collision simulation analysis.The simulation result on the basis of the LS-DYNA calculation method shows that the optimized plan of the new type fender has fairly good safety performance in energy absorption and collision damping.
Radiation for Awakening the Dormant Immune System, a Promising Challenge to be Explored (2014)

Recent advances that have been made in our understanding of cancer biology and immunology show that infiltrated immune cells and cytokines in the tumor microenvironment may play different functions that appear tightly related to clinical outcomes. Strategies aimed at interfering with the cross-talk between microenvironment tumor cells and their cellular partners have been considered for the development of new immunotherapies. These novel therapies target different cell components of the tumor microenvironment and importantly, they may be coupled and boosted with classical treatments, such as radiotherapy. In this work, we try to summarize recent data on the microenvironment impact of radiation therapy, from pre-clinical research to the clinic, while taking into account that this new knowledge will probably translate into indication and objective of radiation therapy changes in the next future.
Information, Blockbusters and Stars? A Study of the Film Industry (1997)

The purpose of this paper is to explore the role of stars and other potential informational signals in the movie business. In the first part of the paper, we explore two alternative economic explanations for the role of stars in motion pictures. The first approach is a signaling view; namely that informed insiders signal project quality by selecting an expensive star. The second approach is the 'rent capture' hypothesis, i.e. that stars receive their marginal value. These two approaches have different implications regarding stars' pay, movie revenues and return on investment. The second part of the paper contains an extensive empirical investigation of a sample of movies produced in the 90's. Univariate analysis seems to show that star-studded films bring in more revenues than other films. However, regression analysis only supports the notion that any big budget investment increases revenues. Sequels, highly visible films and 'family oriented' ratings also contribute to revenues. However, when we measure return on investment, we find that stars or big budgets are not associated with profits; if anything, low budget films seem to do better. This supports again, the 'rent capture' hypothesis. We identify some additional variables that are associated with profitable films.
[The biological effect of high glucose on human periodontal ligament fibroblast]. (2011)

The investigate the effect of high glucose on proliferation, total protein synthesis, alkaline phosphatase (ALP) activities, collagen-I(Col-I) and osteocalcin(OCN) secretion of human periodontal ligament fibroblast(hPDLF) in vitro and the regulative function of insulin in this process.Glucose of different concentration (5.5,15,25,35and 45mmol/L) was used to culture hPDLF and insulin was used for each group as treatment control. 24 hrs after administration, cell proliferation was detected by cell counting kit (CCK-8), total protein synthesis, ALP activities, Col-I and OCN secretion were investigated. Data was analyzed with SPSS 13.0 soft ware package.Glucose of low concentration had no effect on biological function of hPDLF, but glucose of high concentration could inhibit proliferation, total protein synthesis, ALP activities, Col-I and OCN secretion of hPDLF significantly in a concentration-dependent manner. This effect could be blocked by insulin.High glucose could inhibit biological function of hPDLF and such effect could be blocked by insulin.
Hartmann Test of Aspherical Mirrors (1972)

Astronomical aspherical mirrors may be tested in the optical shop with a Hartmann null test. A null test is obtained by placing small wedges over each hole of the Hartmann screen. The wedges have an angle between the two faces such that the spherical aberration with the object and the image at the center of curvature is just compensated.
Phase transitions in non-hydride switchable mirror thin films (2008)

Switchable mirrors modulate incident light by changes in the reflectivity of thin films that are converted by chemical reactions from a metallic reflective state to a semiconducting transparent state. The reactions may be effected by exposure to a gas, by treatment with a liquid reagent, or by electrochemical means. The changes in optical properties coincide with phase transformations. In the examples reviewed here, the reactions are accompanied by substantial volume changes and atomic rearrangement. Bismuth, antimony, and antimony alloy films are switched by electrochemical lithiation. Copper films are electrochemically oxidized to Cu(I) and Cu(II) oxides, which are transparent and opaque, respectively. Morphological changes in all films during cycling lead to degradation in performance without loss of active material. Strategies to improve the cycling stability of these systems are discussed.
Investigating the role of machine translated text in ASR domain adaptation: Unsupervised and semi-supervised methods (2011)

This study investigates the use of machine translated text for ASR domain adaptation. The proposed methodology is applicable when domain-specific data is available in language X only, whereas the goal is to develop a domain-specific system in language Y. Two semi-supervised methods are introduced and compared with a fully unsupervised approach, which represents the baseline. While both unsupervised and semi-supervised approaches allow to quickly develop an accurate domain-specific ASR system, the semi-supervised approaches overpass the unsupervised one by 10% to 29% relative, depending on the amount of human post-processed data available. An in-depth analysis, to explain how the machine translated text improves the performance of the domain-specific ASR, is also given at the end of this paper.
Selective encryption techniques of JPEG2000 codestream for medical images transmission (2008)

In this paper, novel selective encryption image schemes based on JPEG2000 are proposed. The first one encrypts only the code-blocks corresponding to some sensitive precincts. In order to improve the security level we introduce the permutation of codeblocks contributing in the selected precincts. The idea of combining permutation and selective encryption is used in order to minimize the amount of processed data encryption while ensuring the best possible degradation through the permutation.

Many of proposals format compliant encryption schemes for JPEG2000 that have been made encrypt packet body data, but leave header packet in plaintext. The second approach, combines code-blocks data encryption to a cyclic permutation of all packets headers in the bitstream. Actually, in the JPEG2000 codestream, packet header information is specific to the visual content, and it is can be used as a fingerprint of the codestream.

Symmetric encryption AES with CFB mode is used to encrypt in the two schemes.

The proposed schemes don't introduce superfluous JPEG2000 markers in the protected codestream, i.e, its format is compliant to JPEG2000 codestream one. It keeps file format and compression ratio unchanged and doesn't degrade the original error robustness. The proposed scheme works with any standard ciphers and introduces negligible computational cost.
A band pass filter for the 2537   mercury line (1966)

An inexpensive liquid filter for isolation of the 2537 A mercury line has been developed. This filter made possible the measurement of the fluorescence emission spectra of benzene and its derivatives without interference of the remaining mercury lines.
Trapezoidal Motion Profile to Suppress Residual Vibration of Flexible Object Moved by Robot (2019)

The residual vibration when a robot manipulator is operated at high speed needs to be suppressed. These vibrations are generated by the resonance of a flexible object being moved by the robot, and research on control algorithms and motion profiles is ongoing to reduce them. In this paper, we propose a method to reduce the residual vibration of an object moved by a robot manipulator by optimizing the acceleration/deceleration time calculated using the object’s natural frequency. The relationship between acceleration/deceleration time and the residual vibration in a trapezoidal velocity profile is considered by analyzing the scenario when the jerking motion characteristic of such vibrations occurs. The results of experiments using a commercial robot show that residual vibrations can be reduced by the proposed method without the need for an additional feedback control algorithm while transferring a flexible object over small and large distances.
Coupled-Film Memory Elements (1967)

Coupled-film arrays have been fabricated on insulated Cu ground plane with 0.004-in.-wide bit lines on 0.006-in. centers and 0.007-in.-wide word lines on 0.014-in. centers, resulting in an unusually high packing density of 12 000 bits/in.2 A sense signal of 2 mV under worst-case testing conditions has been measured at 200-mA word current (6 nsec risetime) and 15-mA bit current. The low word and bit currents have been achieved by miniaturizing the devices while providing flux closures. The etched Permalloy-Cu-Permalloy bit/sense lines are plated with Permalloy at the edges. The word lines are embedded in ferrite. Permalloy backing on word line and Permalloy embedded in ground further improve flux closure. Available Permalloy materials have intrinsic limitations on the obtainable Hk, Hc, α and the ratio Hc/α Hk (a measure of disturb immunity). The device operating margin can be extended by using doublet word and/or bit currents. The doublet bit current increases the bit disturb threshold, while the doublet word current decreases the bit write threshold. With both doublet bit and word currents, both beneficial effects are achieved.
Corticokinematic coherence mainly reflects movement-induced proprioceptive feedback (2014)

Corticokinematic coherence (CKC) reflects coupling between magnetoencephalographic (MEG) signals and hand kinematics, mainly occurring at hand movement frequency (F0) and its first harmonic (F1). Since CKC can be obtained for both active and passive movements, it has been suggested to mainly reflect proprioceptive feedback to the primary sensorimotor (SM1) cortex. However, the directionality of the brain-kinematics coupling has not been previously assessed and was thus quantified in the present study by means of renormalized partial directed coherence (rPDC). MEG data were obtained from 15 subjects who performed right index-finger movements and whose finger was, in another session, passively moved, with or without tactile input. Four additional subjects underwent the same task with slowly varying movement pace, spanning the 1-5 Hz frequency range. The coupling between SM1 activity recorded with MEG and finger kinematics was assessed with coherence and rPDC. In all conditions, the afferent rPDC spectrum, which resembled the coherence spectrum, displayed higher values than the efferent rPDC spectrum. The afferent rPDC was 37% higher when tactile input was present, and it was at highest at F1 of the passive conditions; the efferent rPDC level did not differ between conditions. The apparent latency for the afferent input, estimated within the framework of the rPDC analysis, was 50-100 ms. The higher directional coupling between hand kinematics and SM1 activity in afferent than efferent direction strongly supports the view that CKC mainly reflects movement-related somatosensory proprioceptive afferent input to the contralateral SM1 cortex.
Large scale ATM switching and optical technology (1992)

ATM switching is equivalent to fixed length packet switching combined with a special routing procedure through the network. A part of the ATM cell header called the virtual channel identifier (VCI) must be read at each switching facility and replaced with a new VCI value. VCI translation is done at the switch input because it is simpler to do it at the same time we determine internal switch routing for each cell. There is at present no way of doing VCI translations in the optical domain.
A General Class of Maximal Codes ror Computer Applications (1972)

The error-correcting codes for symbols from GF (2b) are often used for correction of byte-errors in binary data. In these byte-error-correcting codes each check symbol in GF (2b) is expressed as b binary check digits and each information symbol in GF (2b), likewise, is expressed by b binary information digits. A new class of codes for single-byte-error correction is presented. The code is general in that the code structure does not depend on symbols from GF (2b). In particular, the number of check bits are not restricted to the multiples of b as in the case of the codes derived from GF (2b) codes. The new codes are either perfect or maximal and are easily implementable using shift registers.
Planning Research on Oman: The End of Lehi’s Trail (1998)

Research Article| April 01 1998 Planning Research on Oman: The End of Lehi’s Trail TERRY B. BALL; TERRY B. BALL Search for other works by this author on: This Site Google S. KENT BROWN; S. KENT BROWN Search for other works by this author on: This Site Google ARNOLD H. GREEN; ARNOLD H. GREEN Search for other works by this author on: This Site Google DAVID J. JOHNSON; DAVID J. JOHNSON Search for other works by this author on: This Site Google W. REVELL PHILLIPS W. REVELL PHILLIPS Search for other works by this author on: This Site Google Journal of Book of Mormon Studies (1992-2007) (1998) 7 (1): 12–70. https://doi.org/10.2307/44759915 Cite Icon Cite Share Icon Share Facebook Twitter LinkedIn MailTo Permissions Search Site Citation TERRY B. BALL, S. KENT BROWN, ARNOLD H. GREEN, DAVID J. JOHNSON, W. REVELL PHILLIPS; Planning Research on Oman: The End of Lehi’s Trail. Journal of Book of Mormon Studies (1992-2007) 1 April 1998; 7 (1): 12–70. doi: https://doi.org/10.2307/44759915 Download citation file: Zotero Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All Scholarly Publishing CollectiveUniversity of Illinois PressJournal of Book of Mormon Studies Search Advanced Search The text of this article is only available as a PDF. © Copyright 1998 Foundation for Ancient Research and Mormon Studies1998 Article PDF first page preview Close Modal You do not currently have access to this content.
Insulin is a prominent modulator of the cytokine-stimulated expression of acute-phase plasma protein genes. (1992)

Several endocrine hormones which influence liver metabolism are known to increase in activity during the acute phase of injury or inflammation. We determined whether these hormones have the potential to influence acute-phase protein production in human and rat hepatoma cells. Catecholamines, glucagon, growth hormone, triiodothyronine, and cyclic nucleotides individually or in combination did not modulate the basal or the interleukin-1 (IL-1)-, IL-6-, and dexamethasone-stimulated levels of acute-phase plasma proteins. Insulin, however, was found to be a rapid, nonspecific, and dose-dependent inhibitor of the cytokine and glucocorticoid stimulation of acute-phase protein gene expression and to exert its effect at the transcriptional level. The insulin inhibition applied to all cytokines tested but to various degrees, depending upon the particular acute-phase gene. Insulin resulted in an early and prominent increase in the transcription of genes encoding the AP-1 components of JunA, JunB, and c-Fos, as has been observed for other growth factors. However, the effect of insulin on C/EBP beta was unexpected and paradoxical: while insulin completely inhibited the transcriptional activation of the C/EBP beta gene in cytokine- and dexamethasone-treated cells, the level of cytoplasmic C/EBP beta RNA was elevated. Quantitation of C/EBP beta mRNA by Northern (RNA) blot analysis and of C/EBP beta DNA binding activity by Southwestern (DNA-protein) blot analysis showed that insulin, when combined with cytokines and dexamethasone, stimulated both the mRNA and DNA binding activity by a factor of 1.6 compared with that of cells treated with cytokines and dexamethasone alone. Transient transfection of H-35 and HepG2 cells with a chloramphenicol acetyltransferase (CAT) gene expression vector containing the C/EBP beta response element also resulted in a 1.5-fold increase of C/EBP beta-mediated transcription in insulin-treated cells. Transfection of CAT gene constructs containing increasing lengths of heptaglobin gene 5' flanking sequences indicated that insulin inhibition of IL-6 stimulation required the presence of the region from -4100 to -1030. These results suggest that insulin has the potential to control the transcription of acute-phase genes by at least two separate mechanisms.
Transferring Optical Proximity Correction (OPC) Effect into Optical Mode (2007)

Because of the ever-decreasing feature size in modern photolithography, the complexity of pattern increases dramatically and tape-out time becomes prolonged. It is desirable to transfer OPC process into optical model for the sake of time. In this report, we introduce a novel method of calculating the OPC effect by modifying the optical model, which is equivalent to transferring the OPC effect into the optical model.