gebhart/patrepeval huggingface dataset:
Mechanistic and Exploratory Photochemistry. XV.<sup>1</sup> The Relation of Cyclohexenone to Cyclohexadienone Rearrangements (1966)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTMechanistic and Exploratory Photochemistry. XV.1 The Relation of Cyclohexenone to Cyclohexadienone RearrangementsHoward E. Zimmerman, Robert G. Lewis, John J. McCullough, Albert Padwa, Stuart W. Staley, and Martin SemmelhackCite this: J. Am. Chem. Soc. 1966, 88, 9, 1965–1973Publication Date (Print):May 1, 1966Publication History Published online1 May 2002Published inissue 1 May 1966https://pubs.acs.org/doi/10.1021/ja00961a021https://doi.org/10.1021/ja00961a021research-articleACS PublicationsRequest reuse permissionsArticle Views119Altmetric-Citations33LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
ChemInform Abstract: Stereoselective One‐Pot Synthesis of Vinylsilanes from Aromatic Aldehydes. (2001)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Fast algorithm for implementing spatial frequency analysis of electromagnetic scattering (2016)

In a previous paper, the spatial frequency technique was developed for solving the integral equation (IE) in electromagnetic scattering problems and shown to work faster than many existing solution methods. In this follow-up paper, a new algorithm which takes advantage of the efficient FFT algorithm is developed for solving the IE for scattering from conducting objects. The new algorithm, known as the Fast-SFT, is an efficient, iterative method, which utilizes direct vector multiplications and FFT operations only, to estimate the induced currents. Simulation results are compared with other iterative approaches and shown to work faster than methods such as the conjugate gradient FFT (CG-FFT) method.
Plasmid-Mediated Surface Fibrillae ofYersinia pseudotuberculosis andYersinia enterocolitica: Relationship totheOuterMembrane Protein YOP1andPossible Importance forPathogenesis (1987)

hemagglutination ofguinea pigerythrocytes. Immunoelectron microscopy indicated thatYOP1isastructural component ofthefibrillae. Experiments demonstrating inhibition ofhemagglutination byanti-YOPI monoclonal antibody suggested a potential role forYOP1inadhesion. Insertional inactivation ofthegene coding forYOP1,with resultant loss oftheability toexpressfibrillae, ledtoa significant reduction inthecapacity ofY.enterocolitica, butnotY.pseudotuberculosis, tocolonize theileum oforogastrically infected mice. InbothY.enterocolitica and Y.pseudotuberculosis, inactivation ofthegenescoding forCa2'dependency reduced theability tomaintain intestinal colonization, regardless oftheability toexpressfibrillae. Bothsurface fibrillae andCa2+dependency seem toreflect pathogenic determinants which arerequired fortheestablishment ofY.enterocolitica infection. InY.pseudotuberculosis, however, no clinical significance ofthefibrillae hassofarbeendefined.
In Vitro Activity of a Novel Antimicrobial Agent, TG44, for Treatment of <i>Helicobacter pylori</i> Infection (2006)

Due to concerns about the current therapeutic modalities for Helicobacter pylori infection, e.g., the increased emergence of drug-resistant strains and the adverse reactions of drugs currently administered, there is a need to develop an anti-H. pylori agent with higher efficacy and less toxicity. The antibacterial activity of TG44, an anti-H. pylori agent with a novel structural formula, against 54 clinical isolates of H. pylori was examined and compared with those of amoxicillin (AMX), clarithromycin (CLR), and metronidazole (MNZ). Consequently, TG44 inhibited the growth of H. pylori in an MIC range of 0.0625 to 1 microg/ml. The MIC ranges of AMX, CLR, and MNZ were 0.0078 to 8 microg/ml, 0.0156 to 64 microg/ml, and 2 to 128 microg/ml, respectively. The antibacterial activity of TG44 against AMX-, CLR-, and MNZ-resistant strains was nearly comparable to that against drug-susceptible ones. In a pH range of 3 to 7, TG44 at 3.13 to 12.5 microg/ml exhibited potent bactericidal activity against H. pylori in the stationary phase of growth as early as 1 h after treatment began, in contrast to AMX, which showed no bactericidal activity at concentrations of up to 50 microg/ml at the same time point of treatment. TG44 at 25 microg/ml exhibited no antibacterial activity against 13 strains of aerobic bacteria, suggesting that its antibacterial activity against H. pylori is potent and highly specific. The present study indicated that TG44 possesses antibacterial activity which manifests quickly and is potentially useful for eradicating not only the antibiotic-susceptible but also the antibiotic-resistant strains of H. pylori by monotherapy.
ChemInform Abstract: Photochemical Reaction of 2,3‐Dichloro‐1,4‐naphthoquinone with Enol Silyl Ethers. (1986)

Abstract Reaction of the dichloronaphthoquinone (III) with mixtures of the isomeric trimethyl‐siloxy alkenes (I) and (II) [difficulties in the Separation of (I) from its byproduct (II) during the preparation of (I) from 2‐alkanones lead to the use of the mixtures] gives the oxoalkylated naphthoquinones (IV) [from (I)] and the naphthol derivatives (V) [from (II)].
The Boulton–Katritzky Reaction: A Kinetic Study of the Effect of 5‐Nitrogen Substituents on the Rearrangement of Some (<i>Z</i>)‐Phenylhydrazones of 3‐Benzoyl‐1,2,4‐oxadiazoles (2014)

Abstract The kinetics of the ring‐into‐ring conversion of some new ( Z )‐phenylhydrazones of 3‐benzoyl‐1,2,4‐oxadiazole containing different nitrogen‐substituents at C‐5 ( 3b – d ; X = NHMe, NMe 2 , and NHCOMe) into the relevant triazoles 4b – d have been examined in a wide range of p S + (0.1–11.9) in 1:1 (v/v) dioxane/water solution. The obtained results have been compared with previous data concerning the ( Z )‐phenylhydrazone of 5‐amino‐3‐benzoyl‐1,2,4‐oxadiazole ( 3a ; X = NH 2 ). All of the studied ( Z )‐phenylhydrazones rearrange through three different pathways (specific acid‐catalysed, uncatalysed and general base‐catalysed). The different effects of the substituents on the course of the rearrangement in the three pathways have been examined.
A comparative study of GdAlO 3 perovskite prepared by the sol-gel method using different complexing agents (2006)

This paper presents on the results of the sol–gel preparation of the microcrystalline gadolinium aluminate (GdAlO3, GAP) ceramics at slightly different synthetic conditions. Metal ions generated by dissolving the starting materials of metals in the diluted acetic acid were complexed by different complexing agents (natural and synthetic tartaric acids, 1,2-ethanediol, citric acid, ethanolamine) to obtain the precursors for the GAP. In the sol–gel processing different starting gadolinium materials such as gadolinium nitrate or gadolinium oxide were also employed. Phase transformations, composition and microstructural features in the gels and polycrystalline samples were studied by powder X-ray diffraction analysis (XRD), infrared spectroscopy (IR) and scanning electron microscopy (SEM).
Caractérisation du comportement magnétothermique d'aciers électriques (2005)

International audience
Increased influence of endothelium in obese Zucker rat aorta (1989)

The ability of endothelium to alter contractile events in phenylephrine (PE)-triggered contraction has been tested on ring segments of the thoracic aorta removed from obese Zucker rats (plasma cholesterol 3.63 mM; n = 8) and from age matched lean rats (plasma cholesterol 2.38 mM; n = 8). In normal medium, PE (1 microM) elicited similar contractions in endothelium-denuded arteries of both strains. However, the presence of endothelium reduced these contractile events and the endothelium-dependent relaxation induced by carbachol (10 microM) was higher in obese rats. In rings incubated in Ca2+ free medium containing EGTA (1 mM), PE (1 microM) induced a phasic contraction and a sustained contraction following addition of Ca2+ (2.5 mM) to the medium. The phasic contraction was due to intracellular Ca2+ release, whereas the sustained response was dependent on extracellular Ca2+ influx. In endothelium-free preparations, the size of both the phasic and sustained contraction was similar for the two strains. The Ca2+ antagonist gallopamil (1 microM) reduced the sustained contraction of lean (24%) and obese (34%) rats without affecting the phasic contraction. In preparations possessing endothelium, the sustained, but not the phasic contraction, of both strains was inhibited. This inhibitory effect of endothelium on the sustained contraction was significantly higher in obese than in lean rats. Thus, it can be concluded that phenylephrine elicited quantitatively and qualitatively similar contractions in obese and lean rats. In both strains, the endothelium diminished the contraction induced by PE, however, this effect was more pronounced in obese rats than in lean ones. These results may explain, in part, the described absence of atherosclerotic lesions in the obese strain.
Dual Poly Liner Mobility Optimizes Wear and Stability in THA: Opposes (2011)

Total hip arthroplasty (THA) is an effective intervention for the treatment of arthrosis with excellent survivorship. Nonetheless, dislocation and osteolysis remain significant complications. A dual-mobility acetabular component has been advocated to improve stability and wear. Stability is imparted by increasing the effective femoral head size, which allows a larger range of motion (ROM) before neck-socket impingement occurs. Increasing ROM, however, introduces an additional problem of bony impingement of the trochanter against the pelvis. Consequently, there is little improvement in ROM for heads >36 to 40 mm. A 0.4% incidence of instability at the larger articulation has been reported in primary THA using the dual-mobility liner, which is equivalent to reports for conventional THA. The dual-mobility liner has introduced the unique complication of intraprosthetic dislocation, where the femoral head dissociates at the smaller articulation as a result of polyethylene wear. An incidence of intraprosthetic dislocation of 3.6% has been reported, which far exceeds dislocation of conventional arthroplasty. The dual-mobility liner is a monoblock acetabular component without the capacity for augmented bony fixation. Inability to achieve primary stability has been reported as high as 18% and therefore its usefulness in revision THA is questionable. Proponents of the dual-mobility liner cite improved wear characteristics over conventional THA; however, few studies support this proposition. Retrieval studies have reported that the dual-mobility liner does not avoid wear or osteolysis. Theoretically, it is inconceivable that wear would be diminished with an additional articulation with a huge surface area, where the differential hardness has been reversed to a soft-on-hard bearing.
High Efficacy of Fractionated Stereotactic Radiotherapy of Large Base-of-Skull Meningiomas: Long-Term Results (2001)

The results of this study demonstrate that fractionated stereotactic radiotherapy is safe and effective in the therapy of subtotally resected or unresectable meningiomas. The overall morbidity and incidence subacute and late side effects of this conformal radiotherapy approach were low.
Developmental Status of Hybrids (1999)

Fuel cells are emerging as a major new power generation technology that is particularly suitable for distributed power generation, high-efficiency, and low pollutant emission. An interesting combined cycle, the “HYBRID,” has recently been scoped “on paper” that portends the potential of ultra-high efficiency (approaching 80%) in which a gas turbine is synergistically combined with a fuel cell into a unique combined cycle. This paper introduces hybrid technology to the gas turbine community as a whole, and summarizes the current and projected activities associated with this emerging concept.
ChemInform Abstract: Antiinflammatory/Antiarthritic Ketonic Bisphosphonic Acid Esters. (1998)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
The Hepatitis C Virus Nonstructural Protein 2 (NS2): An Up-and-Coming Antiviral Drug Target (2010)

Infection with Hepatitis C Virus (HCV) continues to be a major global health problem. To overcome the limitations of current therapies using interferon-α in combination with ribavirin, there is a need to develop drugs that specifically block viral proteins. Highly efficient protease and polymerase inhibitors are currently undergoing clinical testing and will become available in the next few years. However, with resistance mutations emerging quickly, additional enzymatic activities or functions of HCV have to be targeted by novel compounds. One candidate molecule is the nonstructural protein 2 (NS2), which contains a proteolytic activity that is essential for viral RNA replication. In addition, NS2 is crucial for the assembly of progeny virions and modulates various cellular processes that interfere with viral replication. This review describes the functions of NS2 in the life cycle of HCV and highlights potential antiviral strategies involving NS2.
Heat shock proteins and their role in the immune regulation of inflammation (2012)

Click to launch & play an online audio visual presentation by Prof. Willem Van Eden on Heat shock proteins and their role in the immune regulation of inflammation, part of a collection of multimedia lectures.
Injection locking phenomena in an active microstrip antenna (1993)

Presents an experimental and computer simulated appraisal of the operational characteristics of an active antenna module. The module is operated in free running mode and also under the influence of a frequency entrainment signal applied at the first subharmonic and at the first harmonic of the free running frequency. The degree to which the behaviour of the module can be influenced in each case is examined and potential application areas for each resultant effect described. Further it is shown that it is possible to quantitatively simulate the behaviour of the module for each case examined using a nonlinear circuit based model.
Chiral Boron‐Bridged Bisoxazolines: Readily Available Anionic Ligands for Asymmetric Catalysis (2005)

Die asymmetrische Cyclopropanierung und Monobenzoylierung von meso-Diolen gelingt mithilfe der Borabox-Katalysatoren 1 (M=Cu) hoch enantioselektiv. Die Borabox-Liganden sind anionische Analoga der Bisoxazoline 2 und werden einfach durch Lithiierung von Oxazolinen und anschließendes Abfangen mit Borhalogeniden hergestellt. Das beachtliche Potenzial von Borabox-Liganden in der asymmetrischen Katalyse wird vorgestellt. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2001/2005/z501111_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
Studies on the Desilicification from High Silica-containing Kraft Liquors Part II (1968)

No work has been reported on the desilicification of kraft liquors by the addition of aluminium sulfate. The reason is probably due to the fact that most of aluminium salts are soluble in alkaline solutions. But the kraft black or green liquor contains only a little amount of free alkali. For that reason, it is thought to be possible to remove silica from the liquor by the addition of aluminium salt. In this paper, the removal of silica from the green liquor was investigated. It is possible from a standpoint of the principle, but there remain some problems concerning the maintenance of sulfidity and the control of supply of chemicals.
Phospholipid Antithromboplastin Not Related to Sphingosine. (1957)

Methods involving separate selective destruction of sphingosine and phospholipid antithromboplastin in mixtures of the two indicate that they cannot be the same. Differences in their chemical and biological properties also support the view that they are distinctly different anticoagulants.
Using midday surface temperature to estimate daily evaporation from satellite thermal IR data (1983)

Abstract The practical experience obtained by our participation in the European project TELLUS (a part of the HCMM programme) led us to state that the thermal inertia concept and sophisticated models are useful for understanding basic processes and for performing informative simulations, but cannot be used for a real estimation of evaporation On the other hand, a simplified procedure like that proposed by Jackson et al. (1977) appears feasible, but its theoretical basis and its field of application are subject to discussion. Two main questions arise, namely, the conditions underlying the use of one instantaneous measurement to estimate daily integrated values, and the significance of the adjustment parameter B in the simplified relationship ETd = Rnd − B(Ts − Ta)i which relates the daily evaporation to daily net radiation by means of one measurement of the surface and air temperature, at a given time of day These questions are discussed with reference to results of recent experiments. A theoretical analysis of the B parameter was undertaken to explain the difference between the value (0.25) derived from an experiment at Crau (south of France) and the value (0.64) proposed by Jackson et al. (1977) for conditions in Phoenix. The influences of wind velocity, thermal stratification and surface roughness are discussed. Consequences of the practical use of the simplified procedure are presented.
Al-doped HfO2/In0.53Ga0.47As metal-oxide-semiconductor capacitors (2011)

Hafnium oxide gate dielectrics doped with a one to two percent of aluminum are grown on In0.53Ga0.47As channels by codeposition of trimethylaluminum (TMA) and hafnium tertbutoxide (HTB). It is shown that the addition of TMA during growth allows for smooth, amorphous films that can be scaled to ∼5 nm physical thickness. Metal-oxide-semiconductor capacitors (MOSCAPs) with this dielectric have an equivalent oxide thickness of 1 nm, show an unpinned, efficient Fermi level movement and lower interface trap densities than MOSCAPs with HfO2 dielectrics grown by sequential TMA/HTB deposition.
Bacterial Resistance to Antibody‐Dependent Defenses (2000)

Bacterial disease results from a dynamic interaction between pathogen and host. Antibody protects against bacterial infection in numerous ways. Agglutination (or clumping) and immobilization of motile organisms are among the conceptually simplest defense mechanisms. Gene cloning and sequencing revealed that leukotoxin (LKT) is part of a family of RTX toxins. Gene cloning and sequencing revealed that LKT is part of a family of RTX toxins. Other members of the family contribute to evasion of antibody defenses as well. Several gram-negative bacteria block the antibody activation of the C cascade, resulting in escape from C-mediated killing. Bacteria lacking a protective coat such as a capsule may avoid antibody-mediated defenses by shedding antigen into the external milieu. Antigenic variation is a mechanism of evading a vigorous antibody response. Some years ago, it was noted that the lipooligosaccharide (LOS) of Haemophilus somnus isolated from calf lungs in a chronic pneumonia study had LOS with different migration patterns in sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) than the LOS of the infecting strain. Microbes divert immune responses away from productive, protective immunity in several ways. Motifs discovered in the sequence analysis provided a basis for functional studies of the protein to aid in understanding its relevance to evasion of antibody-mediated defense. These should help to explain the persistence of H. somnus infection in calf lungs for at least 10 weeks in the presence of specific antibody.
VERTICAL DISTRIBUTION OF SEAWEED SPORES IN A WATER COLUMN OFFSHORE OF NORTH CAROLINA<sup>1</sup> (1980)

ABSTRACT Differences in the vertical distribution of seaweed spores in a 20 m water column 30 km off the coast of North Carolina were documented. Spores were collected on plastic, and glass slides that were subsequently transferred to incubator cultures where germlings were grown and counted. Spores of green algae and bangiophycidean red algae were collected throughout the water column, whereas spores of brown algae and florideophycidean red algae occurred almost exclusively near the bottom. The occurrence of some kinds of spores in the upper water levels suggests relatively large dispersal shadows for those species. The taxa recovered in the upper levels were typically opportunistic organisms, many of them epiphytes. The collection of many Enteromorpha individuals in the upper and mid levels was of particular interest since locally this genus only occurs in abundance in shallow water habitats 35 km or more from the study site.
Multiple Timescale Flight Control Using Reconfigurable Sliding Modes (1999)

Adual-timescaleaircrafte ight-controlproblemisaddressedviacontinuoussliding-modecontrol.Sliding-surface boundary-layer recone guration is used to account for actuator dynamics, dee ection limits, and rate limits. A recone gurable sliding-mode e ight controller is designed that achieves robust, high-accuracy tracking of outerloop command angles before and after damage to an aircraft. Angular rate commands are robustly tracked in an inner loop. The recone gurable e ight-control strategy is based on a continuous sliding-mode controller with direct boundary-layer adaptation for recone guration. On-line explicit system or damage identie cation is not required. Therecone gurablesliding-modee ight-controltechniqueisapplied to anonlineare ight-dynamicsmodelofan F-16 aircraft. Computer simulations demonstrate stability and high-accuracy tracking performance without violation of actuator limits.
Brain metastases in Asian HER2-positive breast cancer patients: anti-HER2 treatments and their impact on survival (2012)

Anti-HER2 treatment before BM was associated with longer TTBM. Anti-HER2 treatment after BM was associated with a survival benefit, especially when both trastuzumab and lapatinib were utilised.