gebhart/patrepeval huggingface dataset:
Increased kilo-electron-volt x-ray yields from<i>Z</i>-pinch plasmas by mixing elements of similar atomic numbers (1995)

Magnesium-coated aluminum wire array Z pinch plasmas have been tested on a 4-MA, 6-TW pulsed electrical generator. A mixture of 80% aluminum and 20% magnesium is observed to maximize the radiated kilovolt x-ray yield at \ensuremath{\ge}50 kJ, which is 50% higher than that obtained with pure aluminum. Spectroscopic analysis and collisional radiative equilbrium models with radiation transport are employed to show that the aluminum-magnesium mixture reduces the opacity of the strongest emission lines, thus increasing the yield by increasing the probability of photon escape. Furthermore, the spectroscopic data also point to the presence of a strong temperature gradient in the pinched plasma that results in the outer magnesium coating of the wires having a higher electron temperature in the pinch. This temperature difference also plays a role in enhancing the kilovolt x-ray yield. The observation of a higher magnesium electron temperature offers evidence that the magnesium reaches the axis first, forming a core that is compressed and heated by the imploding mass of aluminum. Since the emissions from the core are not absorbed by the outer aluminum, the yields are increased. By comparison, aluminum-magnesium alloys imploded on a different but similar generator do not show a temperature difference.
Effects of coil characteristics for femoral nerve magnetic stimulation (2010)

The aim of this study was to compare the efficiency of two coils used for femoral nerve magnetic stimulation and to compare them with electrical stimulation in inducing maximal response of the quadriceps. The mechanical and electromyographic (EMG) responses were dependent on the coil used. The 45-mm double coil showed greater efficiency to elicit a maximal quadriceps response, which was similar to electrical stimulation.
Abstract 5309: Inhibition of cancer stem-like cells in esophageal squamous cell carcinoma with SOCS-1 gene therapy (2019)

Abstract INTRODUCTION: Cancer stem-like cells are thought to be one of the causes of cancer initiation and progression. They are associated with the resistance to radiotherapy and chemotherapy for various types of tumor including esophageal squamous cell carcinoma (ESCC). Therefore, cancer stem-like cells are promising therapeutic targets of cancer. Suppressor of cytokine signaling-1 (SOCS-1) was identified as a negative regulator of various cytokine signaling. We have previously demonstrated that overexpression of SOCS-1 showed a potent anti-tumor effect on ESCC through inhibiting of the JAK/STAT signaling pathway. This study aimed to evaluate the anti-tumor effect of SOCS-1 gene therapy using adenoviral vector (AdSOCS-1) against cancer stem-like cells in ESCC. METHODS: ESCC cell lines were separated into aldehyde dehydrogenase (ALDH) positive and ALDH negative cells by ALDEFLOUR, and then sphere formation assays were performed. The inhibitory effects of AdSOCS-1 and AdLacZ on the sphere formation were evaluated using TE8, TE14 ESCC cell lines. The inhibition of sphere formation was also evaluated using ESCC cells obtained from ESCC PDX mice (ESCC8). Next, the expression of transcription factors associated with cancer stem-like cells in ESCC was evaluated by RT-PCR. The inhibitory effects on tumor formation by AdSOCS-1 were evaluated by tumorigenicity assay using TE8 xenograft mice. RESULTS: In the sphere formation assay, ALDH positive TE8 cells and TE14 cells represented strong sphere formation capacity. Compared with AdLacZ infected ALDH positive cells, sphere formation of AdSOCS-1 infected ALDH positive cells was significantly inhibited. The inhibition of sphere formation was also confirmed in ESCC cells obtained from ESCC8 PDX mouse tumor tissue. Interestingly, the expression level of Sox2, a critical stem cell factor regulated by STAT3, was also decreased by AdSOCS-1. Furthermore, AdSOCS-1 decreased the tumorigenic activity of the ALDH positive ESCC tumor cells. CONCLUSIONS: A potent anti-tumor effect of SOCS-1 gene therapy on ESCC may be partially explained by inhibiting the expression of a STAT3 regulated transcription factor critical for cancer stem-like cells. Citation Format: Ayumi Yamamoto, Eri Munekage, Satoshi Serada, Shigehiro Tsujii, Kosuke Hiramatsu, Minoru Fujimoto, Kazuhiro Hanazaki, Tetsuji Naka. Inhibition of cancer stem-like cells in esophageal squamous cell carcinoma with SOCS-1 gene therapy [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2019; 2019 Mar 29-Apr 3; Atlanta, GA. Philadelphia (PA): AACR; Cancer Res 2019;79(13 Suppl):Abstract nr 5309.
Clinical Significance of Hypertriglyceridemia (1988)

Available data suggest that elevated triglyceride levels in plasma, associated with increased VLDL or chylomicron remnants, are associated with premature coronary artery atherosclerosis. Whether this is a direct effect or as a result of the association of hypertriglyceridemia with decreased HDL as well as decreased LDL particle size remains to be determined. Many families with premature coronary disease have a genetic form of hypertriglyceridemia associated with decreased HDL, or with both decreased HDL and increased LDL cholesterol concentrations. In addition, subjects with severe hypertriglyceridemia in excess of 1000 mg/dl associated with elevation of plasma chylomicrons are at increased risk of developing recurrent pancreatitis. Therefore, triglycerides have been implicated in the pathogenesis of both atherosclerosis and pancreatitis.
ChemInform Abstract: Copper—Zeolites as Catalysts for the Coupling of Terminal Alkynes: An Efficient Synthesis of Diynes. (2009)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Magnetic properties of neptunium Laves phases: Np<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mrow><mml:msub><mml:mrow><mml:mi mathvariant="normal">Al</mml:mi></mml:mrow><mml:mrow><mml:mn>2</mml:mn></mml:mrow></mml:msub></mml:mrow></mml:math>, Np<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mrow><mml:msub><mml:mrow><mml:mi mathvariant="normal">Os</mml:mi></mml:mrow><mml:mrow><mml:mn>2</mml:mn></mml:mrow></mml:msub></mml:mrow></mml:math>, Np<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mrow><mml:msub><mml:mrow><mml:mi mathvariant="normal">Ir</mml:mi></mml:mrow><mml:mrow><mml:mn>2</mml:mn></mml:mrow></mml:msub></mml:mrow></mml:math>, and Np<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mrow><mml:msub><mml:mrow><mml:mi mathvariant="normal">Ru</mml:mi></mml:mrow><mml:mrow><mml:mn>2</mml:mn></mml:mrow></mml:msub></mml:mrow></mml:math> (1974)

The magnetic properties of a series of neptunium cubic C-15-type Laves phases ($\mathrm{Np}{X}_{2}$, where $X=\mathrm{Al}, \mathrm{Os}, \mathrm{Ir}, or \mathrm{Ru}$) have been studied between 1.5 and 300 \ifmmode^\circ\else\textdegree\fi{}K by means of magnetization and nuclear $\ensuremath{\gamma}$-ray resonance measurements. The properties show a systematic variation with neptunium-neptunium distance ${d}_{\mathrm{Np}}$. Thus, Np${\mathrm{Al}}_{2}$ (${d}_{\mathrm{Np}}=3.37$ A\AA{}) is ferromagnetic with a transition temperature ${T}_{c}=56$ \ifmmode^\circ\else\textdegree\fi{}K and an ordered moment of 1.5 ${\mathrm{\ensuremath{\mu}}}_{\mathrm{B}}$/mole; Np${\mathrm{Os}}_{2}$ (${d}_{\mathrm{Np}}=3.26$ A\AA{}) is ferromagnetic with ${T}_{c}=7.5$ \ifmmode^\circ\else\textdegree\fi{}K and an ordered moment of 0.4 ${\mathrm{\ensuremath{\mu}}}_{\mathrm{B}}$/mole; Np${\mathrm{Ir}}_{2}$ (${d}_{\mathrm{Np}}=3.25$ A\AA{}) is antiferromagnetic with ${T}_{c}=7.5$ \ifmmode^\circ\else\textdegree\fi{}K and an ordered moment of 0.6 ${\mathrm{\ensuremath{\mu}}}_{\mathrm{B}}$/mole; and Np${\mathrm{Ru}}_{2}$ (${d}_{\mathrm{Np}}=3.23$ A\AA{}) does not order magnetically down to 1.5 \ifmmode^\circ\else\textdegree\fi{}K. This trend is interpreted in terms of an increase in the delocatlization of the neptunium magnetic moment and the magnetic $5f$ electrons, as ${d}_{\mathrm{Np}}$ decreases.
Application of Plasma-chemical Hybrid Process to Semi-dry Desulfurization Equipment to Glass Melting Furnace (2017)

Nitrogen oxides (NOx) and sulfur oxides (SOx) are the major components of environmental pollution; therefore they should be removed. In this study, NO oxidation process by using ozone gas and NOx removal process by using Na2SO3 solutions combined with semi-dry desulfurization equipment to glass melting furnace were investigated. Experiments were carried out with varying gas-liquid reaction time in the lab-scale experiment and Na2SO3 concentration in the pilot-scale experiment. In the lab-scale experiment, NOx removal efficiency was reached 64.9 % in maximum. Furthermore, in the pilot-scale experiment, when the ratio of the amount of ozone gas to the amount of NO in the exhaust gas was 23 %, NOx removal efficiency was reached up to 17.0 %. There was no effect on desulfurization by applying plasma-chemical hybrid process to semi-dry desulfurization equipment.
Oxidation of Low-Density Lipoprotein by Hemoglobin Stems from a Heme-Initiated Globin Radical:  Antioxidant Role of Haptoglobin (1997)

Hemoglobin, known as a poor peroxidase, has been recently found to be a highly reactive catalyzer of low-density lipoprotein (LDL) oxidation resulting in oxidation of LDL lipids and covalent cross-linking of the LDL protein, apo B. We evaluated three possible mechanisms that may account for hemoglobin reactivity: oxidative activation by globin-dissociated hemin following its transfer to LDL; peroxidase-like reactivity of the ferryl iron active state in intact hemoglobin; and oxidation by a globin radical formed in oxidized hemoglobin. The first mechanism was ruled out because only a minor fraction of hemin was actually transferred to LDL in the process of oxidation. The second mechanism was excluded because hemoglobin ferryl, unlike ferryl of horseradish peroxidase, was not consumed in the process of LDL oxidation. Haptoglobin completely inhibited cross-linking of globin in hemoglobin/H2O2 mixtures but not in myglobin/H2O2, as well as cross-linking of apo B and oxidation of LDL lipids. Haptoglobin could not however abolish the hemoglobin ferryl state, a finding that further supported exclusion of the second mechanism. We conclude that the active species in hemoglobin-induced LDL oxidation is the globin radical, as suggested in the third mechanism. The present findings also show that haptoglobin functions as a major antioxidant thus protecting the vascular system.
The effect of perineural dexamethasone on duration of sciatic nerve blockade: a randomized, double‐blind study (2017)

Addition of 8 mg dexamethasone to 0.5% bupivacaine-epinephrine significantly prolongs the duration of sensorimotor popliteal sciatic nerve blockade, and reduces pain and opioid consumption in patients after major hind foot and ankle surgery.
Single tumor cell uptake and dosimetry of technetium-99m Fab? anti-CD22 in low-grade B-cell lymphoma (2002)

It seems feasible to assess the mean single tumor cell uptake of (99m)Tc targeted by Fab' or minute anti-CD22 in a patient's lymphoma using sorted cell populations, thereby allowing single cell dosimetry. Extrapolation of the absorbed dose from (99m)Tc to cells with higher CD22 expression was made and under certain conditions absorbed doses of 0.1 Gy were obtained, indicating the potential relevance of low-energy electron emitters to therapy.
Specific enhancement of immune responses by BCG: isolation of extracellular DNA from supernatants of specifically stimulated BCG-primed lymphoid cells. (1980)

When lymphocytes obtained from W/Fu rats primed with BCG are cultured in the presence of PPD, they elaborate a factor that is capable of potentiating the specific in vitro generation of cytotoxic lymphocytes to syngeneic (C58NT)D lymphoma cells and to BN alloantigen. Purification of the factor, achieved by gel filtration on Sephadex G-100, was facilitated by using a serum-free culture condition and the removal of the specific stimulating antigen, PPD, after an initial incubation period. The factor isolated contains DNA by its absorption spectrum, resistance to trypsin and RNase, but complete susceptibility to DNAase, and by the presence of ethidium bromide-positive material in the purified sample. It displays a 260/280 nm absorption ratio of 1.6 and a m.w. estimate of 10,000 to 30,000. Electrophoresis of the purified factor on agarose gel yielded three ethidium bromide reactive bands. Data obtained following the slicing and elution of these bands, and then testing for potentiating activity indicated that two of the three bands contained potentiating activity.
Reviews, Catalogues and New Publications (1987)

Cameron. Anne 1981 Daughters of Copper Woman. Vancouver. Press Gang Press. 21. 14 cm. 150 pp. $7.95 603 Powell Street. Vancouver. BC V6A 1H2. Canada. Ferg. Alan. editor 1987 Western Apache Material Culture: The Goodwin and Guenther Collections. Arizona: The University of Arizona Press. ISBN 0‐8165‐1028‐8. 205 pp., 32 color plates, 170 black‐and‐white photographs,. maps,. line drawings, references and suggested readings. $19.95 paperback. Dale Rosengarten 1986 Row Upon Row: Sea Grass Baskets of the South Carolina Lowcountry. South Carolina: The McKissick Museum, University of South Carolina. ISBN 0‐938983‐02‐4 64 pp. 107 blackand‐white photographs,. map, notes, list of basketmakers interviewed, catalog of exhibition, bibliography. $10.00, plus $1.50 postage and handling. Morris. Walter F. Jr. 1987 Living Maya. New York. Harry N. Abrams, Inc., Publishers. 28.5. 23 cm., 224 pp., 125 color plates, approximately 60 line drawings,. maps. Selected Bibliography, Credit Illustrations, wrap‐around color cover. ISBN 0‐8109‐1298‐8. $40. Cloth cover. Lester. Joan A. 1987 We're Still Here. Boston. The Children's Museum. 26. 26 cm., 86 pp., 96 black‐and‐white photographs. References, Objects in the Collection, photo credits. ISBN 0‐940203‐00‐6. No price. Soft cover. Children's Museum, Museum Wharf, 300 Congress St., Boston, MA 02210.
Der Revolutionsbegriff im historischen Materialismus und in der Geschichtswissenschaft (1987)

Article Der Revolutionsbegriff im historischen Materialismus und in der Geschichtswissenschaft was published on November 1, 1987 in the journal Deutsche Zeitschrift für Philosophie (volume 35, issue 11).
Coexpression of atrial natriuretic factor and beta-endorphin in a subpopulation of rat splenic macrophages: age-related differences. (1993)

Separate demonstration of immunoreactive (ir) atrial natriuretic factor (ANF) and ir-beta-endorphin (beta EP) in macrophages of the rat spleen prompted a reexamination of their distribution and cellular localization in addition to their developmental regulation. Double labeling immunohistochemistry was carried out on paraffin-embedded spleen sections of adult male Sprague-Dawley rats. Cells stained positive with antiserum (S118) raised against rat ANF-(99-126) were colocalized in more than 95% of cases with immunofluorescent staining of ir beta EP-(1-31) and distributed sparsely throughout the venous sinusoidal regions of the red pulp. In 1- or 5-day monolayer cultures of adherent splenocytes, 11-16% of the cells stained positive for either irANF or ir beta EP. Under these conditions, more than 95% of irANF- and ir beta EP-positive cells were also fluorescence stained for the histiocyte marker S22 or the rat macrophage marker ED-1. Colorimetric in situ hybridization similarly revealed signals for pro-ANF mRNA in more than 95% of ir beta EP-positive adherent cells. Thus, taken together with previous reports, our present findings suggest that in the rat spleen, both ANF and beta EP are produced by the same population of macrophages. However, the tissue levels and processing of the two peptides over the developmental period of the animal differed markedly in several ways. In splenic extracts of 2-day-old neonatal rats, Northern blot analysis and RIA revealed a greater abundance of pro-ANF mRNA signal and an irANF concentration about 6-fold greater than those in 30-day-old animals. In contrast, the ir beta EP concentration did not vary significantly over the same period, consistent with the level of POMC mRNA. Sephadex G-50 gel chromatography of splenic extracts from 2-day-old animals revealed predominantly higher mol wt forms of irANF and ir beta EP. From days 16-60, a significant proportion of irANF eluted in the same fractions as the mature circulating form, rat ANF-(99-126); the proportion of 3.5-kilodalton ir beta EP increased progressively to become the predominant species in adult tissues. Thus, it appears that although ANF and beta EP are coexpressed by the same population of splenic macrophages, they differ markedly during the developmental period with respect to their constitutive regulation.
Increased Axonal Proteolysis in Myelin-Deficient Mutant Mice (1982)

Protein degradation within retinal ganglion cell axons in vitro is 50 to 110 percent faster than normal in mutant mice exhibiting deficiencies of myelin in the central nervous system. Proteolysis is increased proximally and distally within retinal ganglion cell axons of mice carrying the jumpy mutation or its allele, myelin synthesis deficiency, and is increased distally within those axons of quaking mice. The proteolytic defect is axon (neuron)-specific since the rate of protein degradation within glial cells is normal. Increased axonal proteolysis does not bear a simple relation to hypomyelination since shiverer, another mouse mutant deficient in central myelin, displayed normal rates of axonal protein degradation under the same conditions. These observations suggest an abnormal axon-glial interaction in mice with primary glial defects and raise the possibility that the functioning of histologically normal axons (neurons) may be altered in dysmyelinating diseases.
An algebraic language for graphical query formulation using an extended entity-relationship model (1987)

The Entity-Category-Relationship (ECR) model extends the Entity-Relationship (ER) model with the concepts of subclass and generalization categories. In this paper a graphical representation of the ECR model and its application as the basis for an interactive query language are discussed. The proposed query language is based on algebraic operators that can be used to transform an ECR diagram so that it represents a desired query. Semantics of the algebraic operators are formally defined. A method of implementing the graphical ECR interface for accessing relational database systems is proposed.
Treatment strategy after non-curative endoscopic resection of early gastric cancer (2008)

Surgery remains the standard treatment after non-curative ER in patients with a possible risk of LNM.
The Hydrogenation of Benzene over Copper–Nickel Alloys (1958)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe Hydrogenation of Benzene over Copper–Nickel AlloysW. Keith Hall and P. H. EmmettCite this: J. Phys. Chem. 1958, 62, 7, 816–821Publication Date (Print):July 1, 1958Publication History Published online1 May 2002Published inissue 1 July 1958https://pubs.acs.org/doi/10.1021/j150565a011https://doi.org/10.1021/j150565a011research-articleACS PublicationsRequest reuse permissionsArticle Views212Altmetric-Citations26LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Large-Cage Occupancies of Hydrogen in Binary Clathrate Hydrates Dependent on Pressures and Guest Concentrations (2010)

Balancing the formation and storage pressure with the storage capacity is one of the most significant steps toward developing H2 storage in hydrates. The large-cage occupancies of hydrogen molecules in tetrahydrofuran (THF), acetone, cyclohexanone (CHONE), and methylcyclohexane (MCH) hydrates were investigated by Raman spectroscopy, volumetric gas release measurement, and X-ray diffraction analysis in a pressure region below the equilibrium pressure of pure H2 hydrates at 255 ± 2 K. The results from the measurements show that H2 molecules occupy the large cage of the structure II THF+H2, acetone+H2, and CHONE+H2 hydrates at the suitable pressures and concentrations of promoter guest species, while H2 molecules do not occupy the largest cage of the structure H MCH+H2 hydrates, even around 70 MPa. The present work reveals that the large-cage occupancy of H2 strongly depends on the pressure and the concentration of promoter guest species. The maximum storage amount of H2 in the acetone+H2 hydrate was 3.6 ± 0.1 wt %, similar to that of THF+H2 hydrate, at 74 MPa and 255 ± 2 K. Acetone is superior to THF and CHONE as the promoter based on the relation between pressure and the large-cage occupancy of H2 molecules.
EFFECT OF ANTIDEPRESSANT AND ANTIMANIC DRUGS ON AMINE UPTAKE IN MAN (1974)

Iprindole, a clinically effective antidepressant drug, does not inhibit the amine uptake pump in rat brain or in human vascular tissue measured indirectly through norepinephrine (NE) or tyramine pressure studies. Lithium reduces the NE pressor response in man.
Dystroglycan and Laminins: Glycoconjugates Involved in Branching Epithelial Morphogenesis (1997)

Branching epithelial morphogenesis is crucial for the development of several organs, such as lung, submandibular gland, mammary gland, tooth, pancreas, and kidney. During early embryogenesis, these organs are composed of a small epithelial rudiment surrounded by mesenchymal cells. Interactions between the two tissue compartments induce growth and branching of the epithelium into the mesenchyme. In each tissue, the epithelial branching has tissue-specific features, but there are many similarities both at the morphological and molecular level. Basement membrane components such as laminin have been implicated in the regulation of epithelial morphogenesis. Here data are reviewed that suggest that interactions between laminin-1 and other basement membrane components and the cell surface are important for epithelial morphogenesis in the kidney, lung, and salivary gland.