gebhart/patrepeval huggingface dataset:
The Influence of Corticosteroids on Antibacterial Activity of Surface Active Compounds (1970)

In vitro, antimicrobial activity of dodecyl-di(β- hydroxyethyl)-benzene ammonium chloride (DOBAC) and dodecyl-triphenyl-phosphonium bromide (DTPB), two surface active compounds, was tested in the presence of corticosteroids in doses which have been shown to enhance metabolic activity of bacteria. The experiments were performed with the Warburg technique measuring oxygen consumption of bacterial suspension in resting phase. Staph. aureus and B. pyocyaneus, three strains of each, served as test organisms. On Staph. aureus a marked decrease in antimicrobial activity of DOBAC and DTPB was encountered after addition of corticosteroids (hydrocortisone, methylprednisolone, fluocinolone). A similar, but weaker effect was present in B. pyocyaneus, too. These data suggest that in vitro tests should be performed before different chemotherapeutic are combined in one preparation.
Integrated sensor-based intelligent robot system (1988)

A description is given of the work of the European Economic Community ESPRIT 278 project, which is concerned with the development of an integrated sensor-based (tactile plus vision) robot system capable of intelligent action within the area of workpiece positioning and orientation. A vision system is used to provide an initial estimate of workpiece position and orientation, allowing the robot to grasp the object. During the grasping phase, the tactile sensor confirms, modifies, or improves the initial information provided by the vision system. The project is now at the final phase, and the integrated components show satisfactory performance.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Reversal of multidrug resistance by lipophilic drugs. (1990)

The phenomenon of multidrug resistance implies that a wide spectrum of structurally and functionally unrelated chemotherapeutic drugs are recognized and processed by the molecular system which protects multidrug-resistant (MDR) cells against lipophilic cytotoxic drugs. This suggests that lipophilic agents with low toxicity may also be recognized and processed by this molecular system. At high concentrations these agents might saturate the system, thereby reversing multidrug resistance. In support of this hypothesis, 19 (73%) of 26 arbitrarily chosen lipophilic drugs were in this study found to increase the accumulation of actinomycin D in MDR WEHI 164 cells. The most potent of these drugs were also shown to sensitize these cells to the cytotoxic effect of actinomycin D and doxorubicin. There was a good correlation between the ability of the lipophilic drugs to induce an increased accumulation of actinomycin D in MDR cells and their ability to sensitize these cells to the cytotoxic effect of chemotherapeutic drugs. The ability to reverse drug resistance appeared to be additive, since increased accumulation of actinomycin D was also obtained by combining low concentrations of various lipophilic drugs. This may be a way to reduce the in vivo toxic effect of the lipophilic drugs yet still obtain a reversal of drug resistance. When MDR cells were exposed to lipophilic drugs which reversed drug resistance, the synergistic cytotoxic effect of actinomycin D and tumor necrosis factor was obtained at reduced actinomycin D concentrations.
A new method for JPEG2000 region-of-interest image coding: most significant bitplanes shift (2003)

Region-of-interest (ROI) image coding is one of the new features included in the JPEG2000 image coding standard, where two methods are defined, i.e., the Maxshift method and the generic scaling based method. In this paper, we propose a new JPEG2000 compliant ROI coding method called Most Significant Bitplane Shift (MSBShift) that combines the advantages of the two standard methods. The MSBShift method not only supports arbitrarily shaped ROI coding without coding the shape, but also enables the flexible adjustment of compression quality in the ROI and background. Additionally, the new method can efficiently code multiple ROIs with different priorities in an image.
Opto-Mechanical Design of a Chromotomographic Imager Direct-Vision Prism Element (2013)

Abstract : Chromotomographic Imaging (CTI) offers advantages in remote sensing by resolving intensity distribution spatially, spectrally, and temporally. The Chromotomography Experiment (CTEx) at the Air Force Institute of Technology (AFIT) explores the application of CTI as a space-based observer. Previous work in instrument development has revealed many of the intricacies of component fabrication and how they impact the resolving of image data. The proposed CTEx instrument has as its chromatic dispersion element a direct-vision prism (DVP) that is made to rotate in order to achieve multiple projection angles. Analysis of previous research established the need for a more accurate characterization of the DVP than has been achieved to date. Research herein presents an investigation into precise characterization of a DVP and a proposed mechanical design of the DVP hardware. The findings of this investigation provide the tools to specify fabrication tolerances for the DVP and advance the research effort.
Synthesis and Applications of Protein/Peptide-Polymer Conjugates (2017)

Recent advances in synthetic methodologies have brought us closer than ever to the precision conferred by nature. For example, the control possible in reversible deactivation radical polymerization enables us to design and synthesize macromolecules with unprecedented control over not only the polymer chain ends, but also the side chain functionality. Furthermore, this functionality can be exploited to afford chemical modification of peptides and proteins, with ever-improving site-specificity, yielding a range of well-defined protein/peptide-hybrid materials. Such materials benefit from the amalgamation of the properties of proteins/peptides with those of the synthetic (macro)molecules in question. Here, the latest developments in the synthesis of functional polymers and their use for preparation of well-defined protein/peptide-polymer conjugates will be discussed, with particular attention focused on modulating the stability, efficacy and/or administration of therapeutic peptides.
Electrical Properties of Yttrium-Doped Strontium Titanate under Reducing Conditions (2002)

The electrical conductivity of containing rare earth dopants (Y, La, Pr, Sm, Nd, Gd, or Yb) was measured at 600-900°C in reducing atmospheres. An unusually high conductivity was observed for the yttrium-doped samples compared to those with rare earth dopants, particularly at the composition of the solubility limit where the conductivity at 800°C was 64 S/cm. The conductivity was confirmed to be n-type by thermopower measurements. The oxygen deficiency was determined to be 1% by thermogravimetric analysis. Increasing the strontium vacancy concentration to effected a further improvement in conductivity to 82 S/cm. This material has high structural stability over a broad range of temperature (up to 1400°C) and oxygen partial pressure A simple defect model was developed to explain the change of electrical conductivity as a function of yttrium content and oxygen deficiency. © 2001 The Electrochemical Society. All rights reserved.
A revisitation of generalized Newtonian fluids (2020)

Creating an entry vortex growth simulation to show viscous and elastic fluid behaviors has always been a major challenge for the computational rheology of well-characterized polymer melts with extension thickening. For one thing, it is difficult to ensure stable convergence and reliable solutions via the viscoelastic constitutive equations at a relatively high Deborah number. From a revisitation of the generalized Newtonian fluids (GNFs), deriving the weighted viscosity is natural with the coexistence of shear and extensional flow; it is called the eXtended GNF (GNF-X) model. Herein, 3D contraction flow simulations incorporating the GNF-X weighted viscosity were significantly carried out over a wide range of Deborah numbers. Numerical results regarding changes in vortex sizes exhibit the same trend of experimental observations, while the predictive accuracy is enhanced for a quantitative comparison. More importantly, the vortex formation, in terms of the weighted viscosity and the extensional flow, is demonstrated with supporting evidence.
Encapsulation Methods for Transport of ATM Cells/Frame Over IP and MPLS Networks (2002)

[reaction: see text] The synthesis of a complex hybrid oxime library is reported utilizing convergent ligation of alkoxyamine and carbonyl monomers via "chemical domain shuffling". Initial biological screening of the library against human small cell lung carcinoma (A549) cells led to the identification of a novel hybrid dimer in contrast to the corresponding monomeric compounds which were found to be inactive.
Area-optimized low-latency approximate multipliers for FPGA-based hardware accelerators (2018)

The architectural differences between ASICs and FPGAs limit the effective performance gains achievable by the application of ASIC-based approximation principles for FPGA-based reconfigurable computing systems. This paper presents a novel approximate multiplier architecture customized towards the FPGA-based fabrics, an efficient design methodology, and an open-source library. Our designs provide higher area, latency and energy gains along with better output accuracy than those offered by the state-of-the-art ASIC-based approximate multipliers. Moreover, compared to the multiplier IP offered by the Xilinx Vivado, our proposed design achieves up to 30%, 53%, and 67% gains in terms of area, latency, and energy, respectively, while incurring an insignificant accuracy loss (on average, below 1% average relative error). Our library of approximate multipliers is open-source and available online at https://cfaed.tudresden.de/pd-downloads to fuel further research and development in this area, and thereby enabling a new research direction for the FPGA community.
Controlled Fusion and Plasma Physics, (Report on the Sixth European Conference, Moscow, 30 July - 3 August 1973) (1973)

The International Atomic Energy Agency organizes international conferences on controlled thermonuclear fusion and plasma physics every three years. It is, however, clear that intervals of three years are very long; for this reason, the European conferences on controlled fusion and plasma physics are held in between the IAEA Conferences and have recently also acquired international status.
The Arabidopsis embryonic shoot fate map (2000)

A fate map has been constructed for the shoot apical region of the embryo of the dicotyledonous plant Arabidopsis thaliana using spontaneously arising clonal albino sectors caused by the chloroplast mutator 1-2 mutation. Chimeric seedlings exhibiting albino sectors shared between the cotyledons and first true leaves revealed patterns of organ inclusion and exclusion. Frequencies of clone sharing were used to calculate developmental distances between organs based on the frequency of clonal sectors failing to extend between different organs. The resulting fate map shows asymmetry in the developmental distances between the cotyledons (embryonic leaves) which in turn predicts the location of the first post-germination leaf and the handedness of the spiral of leaf placement around the central stem axis in later development. The map suggests that embryonic leaf fate specification in the cotyledons may represent a developmental ground state necessary for the formation of the shoot apical meristem.
Carbonization Rate of Soot Precursor Particles (1996)

Abstract The presence of soot precursor particles in hydrocarbon diffusion flames is made clearly evident by means of contemporary sampling techniques in combination with transmission electron microscopy (TEM). These particles are the immediate predecessors of mature, partially dehydrogenated carbonaceous soot aggregates, and recent analytical tests indicate they contain a mixture of polycyclic aromatic hydrocarbons. In this work, the conversion rate of precursor panicles to carbonaceous soot aggregates is investigated. In one method the time interval for the morphological conversion of precursor particles to aggregates is observed in diluted diffusion flames. Temperature profiles are measured by rapid insertion thermocouple thermometry. This information is supplemented by the observation of the sudden decrease of the hydrogen mole fraction of soot precursor particles as measured by laser microprobe mass spectrometry. The Arrhenius rate constants for the carbonization of precursor particles are derived from these measurements. Illustrations of the use of this data in achieving high combustion efficiencies and reduced soot formation in combustion devices are discussed.
First preliminary results of an observation of <i>Ginkgo Biloba</i> treating patients with autistic disorder (2009)

Deficits in reciprocal social interaction, verbal and nonverbal communication, and imaginative activity are the main characteristics of autism. From the psychopharmacological point of view, clonidine, metylphenidate and neuroleptics may improve some of these aspects, but with a remarkable risk of adverse side effects. In our observational study, three patients received 2 x 100 mg Ginkgo Biloba EGb 761 for 4 weeks and showed some improvement on the Aberrant Behavior and Symptom Checklist. These results suggest, that Ginkgo Biloba might be effective at least as an add-on therapy.
Haemodynamics and tissue specificity with isradipine (1993)

The significant effects of isradipine in producing arterial vasodilation and mild negative chronotropic effects without significant negative inotropic effects suggests that this agent should provide excellent antihypertensive efficacy in the treatment of perioperative hypertension. Isradipine may prove to be a safe antihypertensive treatment in patients with impaired ventricular function (cardiac failure), impaired myocardial perfusion (ischaemia), and in cases of selected conduction abnormalities or arrhythmias. The demonstration that its effects are limited to vascular resistance rather than vascular capacitance is an important distinguishing feature of isradipine compared with other antihypertensive agents. Finally, the potential application of this dihydropyridine calcium antagonist for cytoprotection and its effects on atherosclerosis remain exciting therapeutic prospects.
Sol-Gel Preparation and Characterization of SiO<sub>2</sub>/TiO<sub>2</sub> Composite Mesoporous Materials with Bacterial Cellulose for Photocatalysis of Methyl Orange (2012)

SiO2/TiO2 composite mesoporous materials prepared by sol-gel method with bacterial cellulose（BC）as a surface esteriﬁcation agent and porous template was as photocatalyst in the degradation of methyl orange（MO）in water under UV- irradiation. The results show that the best heat treatment condition is at 600°Cfor 3 h and the optimum content of SiO2 is 30% (30 denotes the weight percent of SiO2). The photoactivity of 30SiO2/TiO2 catalyst prepared with BC was much better than that of reference catalyst prepared with no BC. An addition of BC not only raises the adsorbability of the photocatalyst, but also effectively inhibits anatase-rutile transformation and effectively induce amorphous-anatase transformation of TiO2. The BET surface area of 30%SiO2/TiO2 composite mesoporous materials was the largest. The resulting mesoporous materials showed a high photocatalytic activity for the photodegradation of methyl orange in the UV-irradiation.
The effect of ramipril on ambulatory blood pressure: a multicenter trial. (1991)

The antihypertensive efficacy of ramipril was evaluated using 24-h noninvasive ambulatory sphygmomanometry in this double-blind, placebo-controlled study. One hundred subjects with mild-to-moderate essential hypertension were randomized to ramipril, 10 mg or placebo once daily for a 4-week treatment period. Ramipril decreased systolic and diastolic blood pressures throughout the 24-h period after dosing. Blood pressures measured manually 24 h postdose also showed that ramipril significantly reduced supine and standing blood pressures when compared with placebo. Incidences of adverse events were similar in the two study groups. Ramipril proved to be a well-tolerated agent with a sustained 24-h antihypertensive effect in this study.
Hand-held optoacoustic imaging: A review (2018)

Optoacoustic imaging is a medical imaging modality that uses optical excitation and acoustic detection to generate images of tissue structures based up optical absorption within a tissue sample. This imaging modality has been widely explored as a tool for a number of clinical applications, including cancer diagnosis and wound healing tracking. Recently, the optoacoustic imaging community has published a number of reports of <i>hand-held</i> optoacoustic imaging devices and platforms; these hand-held configurations improve the modality's potential for commercial clinical implementation. Here, we review recent advancements in <i>hand-held</i> optoacoustic imaging platforms and methods, including recent pre-clinical applications, and we present an overview of the remaining limitations in optoacoustic imaging that must be addressed to increase the translation of the modality into commercial and clinical use.
Scalable ultrapeer-based DHT protocol for file sharing (2009)

In this paper, we present a novel file searching protocol to structure a DHT ring consisting of only ultrapeers, not all the nodes. The DHT ring in this protocol is much less sensitive to the churn rate because ultrapeers have much longer uptime compared with leaf nodes. Thus, this feature makes the protocol more scalable and efficient than the previous DHT ones in terms of costs of file search, node join and leave operations and the number of routing table entries each node should maintain. Moreover, it is more effective for locating rare files than Gnutella-like searching protocols.
Wireless digital home networking based on cognitive radio (2007)

The limited spectrum resource, the inefficient spectrum utilization and the in-band interference from domestic appliances necessitate a new communication paradigm in wireless digital home networks (WDHNs). In this paper, we propose the network and protocol architectures of wireless digital home networks based on cognitive radio technology, which exploits licensed or unlicensed spectrum and enables dynamic spectrum access in wireless networks. The functionalities and components of the proposed protocol architecture are also presented in details.
Tension string structure for planetary entry vehicles. (1967)

Covers advancements in spacecraft and tactical and strategic missile systems, including subsystem design and application, mission design and analysis, materials and structures, developments in space sciences, space processing and manufacturing, space operations, and applications of space technologies to other fields.
Corrosion Fatigue Investigations of CrNiMoN Austenitic Stainless Steels (2011)

Abstract CrNiMoN austenitic stainless steels are common materials for applications in corrosive environments, especially chloride containing solutions. Steels of this type stand out through their ability to passivate, their good mechanical properties and high ductility. Previous investigation on a solution annealed and cold worked superaustenitic CrNiMoN27-30-3-0.3 showed that the fatigue limit is just slightly decreased in 43 wt% CaCl2 solution compared to inert glycerine. In this paper a conventional austenitic stainless steel with 14 wt% Ni and 18 wt% Cr (EN number 1.4441) has been investigated in solution annealed and cold worked condition and the results are compared with the superaustentic stainless steel. Stress versus number of cycle curves have been recorded in 43 wt% CaCl2 solution and inert glycerine at 120°C. A stress ratio (R-value) of 0.05 was chosen to avoid destruction of the fracture surfaces, as just tensile stresses were applied. A test frequency of 20 Hz was used as this frequency is comparable to loading frequency in applications. Fracture surfaces of specimens which failed after relatively short time and close to the fatigue limit have been excessively investigated in a high resolution scanning electron microscope (SEM) and evaluated as a function of the medium, applied stress and cold worked state. The effect of the medium and cold deformation on crack initiation and propagation is critically discussed. Additionally electrochemical investigations and immersion tests have been performed.
Cloning and characterization of a thermolabile v-src gene for use in reversible transformation of mammalian cells. (1992)

The use of temperature-sensitive (ts) src mutants for studies of cell transformation and differentiation has been limited by the availability of cloned ts-src genes that are inactivated at temperatures compatible with growth of mammalian cells. In this report, we describe the cloning and characterization of the tsLA90src gene, which displays tight thermal sensitivity at 39.5 degrees C. Nucleotide sequence comparison of tsLA90 and wild-type src genes from the Schmidt-Ruppin subgroup A and D strains of Rous sarcoma virus (RSV) revealed four amino acid differences in tsLA90src. Substitution of one of these residues (Lys-280) from tsLA90src with its wild-type homolog (Glu-280) caused a reversion to a wild-type src phenotype. The cloned tsLA90 gene, designated tsUP1, was introduced into avian and mammalian retroviral vectors. Chicken embryo fibroblasts and immortalized mouse 3T3 cells infected with these viral vectors displayed a temperature-dependent transformed phenotype as assessed by cell morphology, secretion of plasminogen activator, transcriptional activation of the primary response genes, Egr-1 and TIS 10, and stimulation of tyrosine phosphorylation. In addition, chicken myoblasts (infected with RSVtsUP1) showed a temperature-dependent differentiation into myotubes. Thus, this cloned src gene should be ideally suited for inducing reversible transformation and differentiation of mammalian cells in culture.
Homer's Metre. A Practical Guide for Reading Greek Hexameter Poetry. Bristol Classical Press, Bristol, 1986. Pp. 40. Paper £2.95; <i>Vergil's Metre</i>. A Practical Guide for Reading Latin Hexameter Poetry. Bristol Classical Press, Bristol, 1986. Pp. vi + 97. Paper £4.95. (1987)

Homer's Metre. A Practical Guide for Reading Greek Hexameter Poetry. Bristol Classical Press, Bristol, 1986. Pp. 40. Paper £2.95; Vergil's Metre. A Practical Guide for Reading Latin Hexameter Poetry. Bristol Classical Press, Bristol, 1986. Pp. vi + 97. Paper £4.95. - Volume 34 Issue 2
Use of a Temperature Gradient Measuring Device in Monitoring of Diabetic and Critically Ill Patients (2007)

A device realizing the simultaneous measure of the central body temperature (Tc), the superficial one (Ts) and their difference (Dt), was proposed for permanent energetic balance evaluation in humans. A program was elaborated to command the intravenous delivery of insulin by a pump depending on the value and trends of Dt. The use of this device for monitoring of decompensated diabetic patients allowed their easier stabilization. In critically ill patients (post transplantation, myocardium infarction) it had a diagnostic and prognostic value, and was helpful for optimization of conventional and insulin therapy.