gebhart/patrepeval huggingface dataset:
A Simple, Rapid and Mild One Pot Synthesis of Benzene Ring Acylated and Demethylated Analogues of Harmine under Solvent-free Conditions (2008)

A simple, rapid, solvent-free, room temperature one pot synthesis of benzene ring acylated and demethylated analogues of harmine using acyl halides/acid anhydrides and AlCl3 has been developed. Eight different acyl halides/acid anhydrides were used in the synthesis. The resulting mixture of products was separated by column chromatography to afford 10- and 12-monoacyl analogues, along with 10,12-diacyl-11-hydroxy products. In five cases the corresponding 10-acyl-11-hydroxy analogues were also obtained. Yields from the eight syntheses (29 products in total) were in the 6-34% range and all compounds were fully characterized.
A detailed understanding of the electronic bipolar resistance switching behavior in Pt/TiO<sub>2</sub>/Pt structure (2011)

The detailed mechanism of electronic bipolar resistance switching (BRS) in the Pt/TiO2/Pt structure was examined. The conduction mechanism analysis showed that the trap-free and trap-mediated space-charge-limited conduction (SCLC) governs the low and high resistance state of BRS, respectively. The SCLC was confirmed by fitting the current–voltage characteristics of low and high resistance states at various temperatures. The BRS behavior originated from the asymmetric potential barrier for electrons escaping from, and trapping into, the trap sites with respect to the bias polarity. This asymmetric potential barrier was formed at the interface between the trap layer and trap-free layer. The detailed parameters such as trap density, and trap layer and trap-free layer thicknesses in the electronic BRS were evaluated. This showed that the degradation in the switching performance could be understood from the decrease and modified distribution of the trap densities in the trap layer.
Spatiotemporal inferences for use in building detection using series of very-high-resolution space-borne stereo images (2015)

Automatic building detection from very-high-resolution (VHR) satellite images is a difficult task. The detection accuracy is usually limited by spectral ambiguities and the uncertainties of the available height information. Feature extraction and training sampling collection for supervised methods are other sources of uncertainty. Most widely used VHR sensors have shorter revisit cycles (IKONOS/GeoEye-1/2, 3 days; WorldView 1/2, 1.1 days) due to large off-nadir viewing angles and hence are able to perform consistent acquisition of mono or stereo images. In this article, we investigate the possibility of using high-temporal stereo VHR images to enhance remote-sensing image interpretation under the context of building detection. Digital surface models, which contain the height information, are generated for each date using semi-global matching. Pre-classification is performed combining the height and spectral information to obtain an initial building probability map. With a reference land cover map available for one date, the training samples of the other dates are automatically derived using a rule-based validating procedure. A spatiotemporal inference filter is developed considering the spectral, spatial, and temporal aspects to enhance the building probability maps. This aims at homogenizing the building probability values of spectrally similar pixels in the spatial domain and geometrically similar pixels in the temporal domain, while being robust to the silhouette of the images and geometric discrepancies of the multitemporal data. The effectiveness and robustness of the proposed method are evaluated by performing three experiments on six stereo pairs of the same region over a time period of five years (2006–2011). The area under curve (AUC) of the receiver operating characteristic and kappa statistic (κ) are employed to assess the results. These experiments show that spatiotemporal inference filtering largely improves the accuracy of the building probability map (average AUC = 0.95) while facilitating building extraction in snow-covered images. The resulting building probability maps can be further used for other applications (e.g. building footprint updating).
Relaxation of Strained-SOI substrates by RTA process (2006)

Three different type strained-Si substrates, EPI, SGOI and SSOI, were evaluated by newly developed high-resolution UV-Raman spectroscopy. The structure relaxation occurred by RTA at 1050/spl deg/C. The Raman peak shifted toward larger wavenumber after RTA for SSOI, indicating strain relaxation. The peak shifted toward lower wavenumber in the case of EPI due to the Ge diffusion rather than strain relaxation. The SGOI showed complex characteristics of SSOI and EPI.
Book reviews (1991)

Kingship, Law and Society: Criminal Justice in the Reign of Henry V. Edward Powell. Oxford. 1989. Clarendon Press, xii + 319 pp. (incl. index). £35.00 cased. Sir Henry Maine: A Study of Victorian Jurisprudence. R.C.J. Cocks. Cambridge. 1988. Cambridge University Press, viii + 224 pp. (incl. index). £25/$49.50 cased. The Birth of the English Common Law (2nd ed). R. C. Van Caenegem. Cambridge. 1988. Cambridge University Press, xviii + 160 pp. (incl. index). £27.50/ $39.50 cased, £9.50/$13.95 limp. Inventing the Industrial Revolution. The English Patent System 1660–1800. Christine Macleod. Cambridge. 1988. Cambridge University Press, xii + 302 pp. £25 cased. The Constitutional Jurisprudence of the Federal Republic of Germany. D.P. KOMMERS. Duke University Press. 1990. xxxvi + 590 pp. (incl. index). £29.25 paperback. Sokrates. Johannes Irmscher. (3rd ed.) Leipzig. 1989. Verlag Phillip Reclam jr. 120 pp. (inch index). The Welsh Laws. T.M. Charles‐Edwards. Cardiff. 1990. The University of Wales Press for the Welsh Arts Council. 106pp. £3.50 limp.
Mars Pathfinder entry temperature data, aerothermal heating, and heatshield material response (1998)

The Mars Pathe nder probe contained instrumentation that measured heatshield temperatures during entry. A description of the experiment, the data, and an analysis of the entry environment and material response are presented. Navier ‐Stokes forebody heating calculations show a peak unblown radiative-equilibrium heat e ux of 118W/cm 2 at thestagnation point and120 W /cm 2 on theshoulderforturbulente ow. Theheatload is3.8 kJ /cm 2 on thenose,decreases along thefrustum,then increasesto 2.7 ‐3.1kJ/cm 2 on theshoulder depending on the onset time forturbulence. One-dimensional charringmaterialresponseiscalculated using threedifferentmodels.Stagnationpoint temperature data are consistent with about 85% of fully catalytic laminar heating. Shoulder temperature data are inconclusive, but are consistent with fully catalytic laminar heating or with 85% of fully catalytic heating with early onset of turbulence. Aft temperature data indicate a peak heat e ux and heat load of about 1.3 W /cm2 and 70 J/cm 2 , respectively. The aft heating proe le is about 20 s longer than the forebody heating proe le. Bondline temperaturedata, although not useful forquantitative analysis of aerothermal heating, clearly showtheheatshield had adequate thickness margins for the actual entry.
Synthesis of 3-Substituted 3-(Trimethylsiloxy)pyrrolidines from β-Aminoketones and Lithium Trimethylsilyldiazomethane (2009)

Lithium trimethylsilyldiazomethane reacted withN-benzyl--aminoketones at -78 °C in THF to give 3-substituted 1-benzyl-3-(trimethylsiloxy)pyrrolidines in moderate to good yields.
Acoustical measurements in ancient theatres: uncertainty in prediction models (2015)

Although the remarkable acoustical apparatus of Greek and Roman theatres is generally recognized, it is difficult to assess it nowadays with objective measurements. In fact, actual conditions of most ancient theatres do not allow objective acoustic characterization, since buildings are often strongly damaged or architecturally incomplete. Only for the best-preserved ones, ISO 3382-1 was used to perform acoustical measurements, even though it refers to indoor environments. Thus, ancient theatres acoustics needs to be evaluated with alternative methods. One possible option consists in using prediction models, which could simulate theatres' lost acoustic characteristics. In this study, two kinds of prediction software, Odeon and CATT-Acoustic, were investigated comparing the reliability of their results. The Greek theatres of Syracuse and Tyndaris were chosen for a measurement campaign: uncertainty in measured results was established based on the GUM recommendations. Then, attested the compatibility of simulations results to in situ measurements, the uncertainties of both software were calculated too.
Hybrid, explicit-implicit, finite-volume schemes on unstructured grids for unsteady compressible flows (2016)

The motivation for using hybrid, explicit-implicit, schemes rather than fully implicit or explicit methods for some unsteady high-speed compressible flows with shocks is firstly discussed. A number of such schemes proposed in the past are briefly overviewed. A recently proposed hybridization approach is then introduced and used for the development of a hybrid, explicit-implicit, TVD (Total Variation Diminishing) scheme of the second order in space and time on smooth solutions in both, explicit and implicit, modes for the linear advection equation. Further generalizations of this finite-volume method for the Burgers, Euler and Navier-Stokes equations discretized on unstructured grids are mentioned in the concluding remarks.
The effects of relative timing of sirolimus and cyclosporine microemulsion formulation coadministration on the pharmacokinetics of each agent* (1998)

Introduction Sirolimus and cyclosporine (INN, ciclosporin) share the same cytochrome P4503A metabolic pathways, and both drugs are substrates for p-glycoprotein countertransport. These factors most likely affect the bioavailability of both drugs. This study served to examine whether the timing of the administration of cyclosporine and sirolimus might significantly affect the relative bioavailability of one or both of these drugs. Methods In this randomized crossover trial, 24 stable kidney transplant recipients who were treated after transplant with a combination of sirolimus, cyclosporine, and prednisone for at least 3 months before study initiation, received individualized doses of sirolimus once daily and cyclosporine in the microemulsion formulation twice a day. A total of 20 patients completed the full crossover design. Patients were randomized to one of two dosing schedules: 10 of the patients who completed the study received the morning doses of sirolimus and cyclosporine concomitantly for the first 7 days (schedule I), and from days 8 to 14 the sirolimus dose was administered 4 hours after the morning cyclosporine dose. The of the patients received the sirolimus dose 4 hours after the morning cyclosporine dose for the first 7 days (schedule II), and from days 8 to 14 they received concomitant morning doses of cyclosporine and sirolimus. Pharmacokinetic profiles of sirolimus and cyclosporine performed on all patients on days 7, 14, and 15 yielded the area under the concentration-time curve (AUC), peak concentration (Cmax), time to Cmax (tmax), trough cyclosporine concentration (Co), and trough sirolimus concentration (Co) values. Results Sirolimus AUC and sirolimus trough levels were consistently and significantly higher when both cyclosporine and sirolimus were administered concomitantly than when they were administered 4 hours apart. No effect attributable to timing of drug administration could be found on cyclosporine pharmacokinetic parameters. Conclusion This study shows that the relative timing of administration of cyclosporine and sirolimus significantly affects the blood concentrations of sirolimus. Clinical Pharmacology & Therapeutics (1998) 63, 48–53; doi:
A framework for distributed mobile robotics (2009)

This thesis presents a means of coordinating a many-to-many distributed marsupial robotic team in order to maximize the amount of time that the robots deployed by the marsupials are able to effectively carry out their mission. Solutions to this problem are important when distributed robotic teams may be used to augment or replace humans who would otherwise be exposing themselves to hazardous or potentially fatal situations such as search and rescue in collapsed structures or identification, monitoring, and removal of harmful environmental contamination. The goal of this coordination is to minimize the power expended obtaining more energy by the deployed robots. This is accomplished by continuously relocating energy sources to meet the needs of the team. We will show that the optimal solutions to this problem are NP-hard.
To solve this problem when scaled to large numbers of mobile docking stations and deployable robots, a heuristic-based coordination algorithm is required. Performance of the coordination algorithm is measured based upon the mean % time the deployable robots are able to actively carry-out their mission, are recharging, or are unable to carry out their mission because they are attempting to reach a source of power. Additional metrics include the number of robots which are unable to successfully obtain power and the number of times the robots are able to successfully recharge themselves. The computational complexity of this coordination algorithm is such that in many (but not all cases), the docking stations are able to choose their position using convex optimization techniques ensuring scalability to large numbers of systems. In the cases that convexity is not possible either directly or through relaxations of the problem, docking stations are able to choose their location through gradient descent or other methodologies at higher computational costs. For comparison purposes simulations were conducted that illustrate that when moving the docking stations in accordance to this strategy, there are significant improvements in nearly all metrics compared to having docking stations at fixed locations within the environment.
Getting Started (2006)

In part I of this book we surveyed the fundamental principles and techniques underlying the creation of musical theater. Once you have grasped the basic techniques and principles, the best way to learn to write musical theater is to write, and then to present what you have written to an audience of some kind. No book can provide a substitute for that, but in this part of the book we can help you get started. We will use a variant of the tutorial approach, in which you can follow us step-by-step through the initial stages of writing a new musical. We will begin two musical theater projects; you can "look over our shoulders" to see how we proceed and, if you like, second-guess the choices we made. Because the processes of writing adaptations and originals are so different, our "tutorials" will include one project of each kind. The point of this approach is to reduce the anxiety of starting a new show from scratch, by breaking the process down into stages and showing how it can be done.KeywordsNevada Test SiteHenry VIIIRoyal PalaceHalf SisterGood MusicalThese keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
A Method of Determining Equivalent Circuit Parameters of an Induction Motor Fed from Various Inverters (1987)

A new method for determining the equivalent circuit parameters of the voltage inverter-fed induction motor is presented. According to this method, the iron loss and the mechanical loss can be calculated accurately at various frequencies. The skin effect in the harmonic secondary equivalent circuit can be also taken into consideration. The secondary resistance can be expressed approximately by a linear function of the frequency and the secondary leakage inductance can be expressed by the power function of the frequency. The load characteristics of the inverter-fed induction motor are also calculated using the motor parameters obtained by this method. In order to verify this new method, these results are compared with the experimental results.
Biomechanical analysis of rehabilitation in the standing position (1991)

Biomechanical analysis of the two-dimensional models composed from roentgenographic pictures and electromyographic analysis of the shear force exerted on the tibia during standing on both legs were conducted in 21 young adult males. The simultaneous contraction of the quadriceps and hamstrings was observed in all electromyograms. Amplitude observed on electromyograms of the hamstrings increased as the trunk flexion angle increased. The calculated average values of shear force were negative at every knee flexion angle (negative value means posteriorly directed force). As the trunk flexion angle increased, posterior drawer force increased at knee flexion angles of 30 degrees and 60 degrees. The simultaneous contraction of the quadriceps and the hamstrings was considered to be the main factor that influenced these results. Standing on both legs with knee and trunk flexion was considered to be applicable in the early stages after anterior cruciate ligament reconstruction.
A simple model for heat and mass transfer in absorption cooling systems (ACSs) (1996)

The article presents a simple technique for the purpose of heat and mass transfer analysis in an ACS. The LiBr/water ACS was selected as an example. based on optimum operation conditions (i.e., the maximum cooling temperature delivered by the ACS), simple but effective expression were derived in terms of the mass flow rate of absorbent—the most important parameter for practical design calculations. The results show that the proposed technique provides, for practical application purposes, a useful tool for a general analysis of the ACS as well as for the system design purpose.
Detection of Lymph Node Micrometastases in Colorectal Cancer (2003)

The presence of lymph node metastases is the single most important prognostic factor of colorectal cancer. However, almost one-third of patients considered metastases-free by routine histochemical analysis of lymph nodes subsequently develop tumour recurrence. More sensitive methods capable of detecting the small deposits of disseminated cancer cells forming micrometastases may provide a basis for powerful new prognostic markers and enhanced staging and treatment of patients with colorectal cancer. We present a review of recent methodology utilized to detect lymph node micrometastases in colorectal cancer, focusing on immunohistochemical staining and DNA- and RNA-based methods. Immunohistochemical staining is sensitive when single tissue sections are in focus, but is highly dependent upon the sectioning level, giving low overall sensitivity for whole lymph nodes unless the number of sections is high. Recent nucleic acid-based methods seem to have higher overall sensitivity, but have so far been used in a relatively limited number of studies, mostly without data on clinical outcome. Using multiple markers and sentinel node mapping can enhance the specificity and sensitivity of micrometastasis detection. Further investigation, however, is required before the most recent methodological developments can be incorporated in routine pathological examination.
Quantitation of hepcidin in serum using ultra‐high‐pressure liquid chromatography and a linear ion trap mass spectrometer (2010)

Hepcidin is a peptide hormone that functions as a key regulator of mammalian iron metabolism. Biological levels are increased in end-stage renal disease and during inflammation but suppressed in hemochromatosis. Thus hepcidin levels have diagnostic importance. This study describes the development of an analytical method for the quantitative determination of the concentration of hepcidin in clinical samples. The fragmentation of hepcidin was investigated using triple quadrupole and linear ion trap mass spectrometers. A standard quantity of a stable isotopically labelled hepcidin internal standard was added to serum samples. Extraction was performed by protein precipitation and weak cation-exchange magnetic nanoparticles. Chromatography was carried out on sub 2 microm particle stationary phase, using ultra-high-pressure liquid chromatography and a linear ion trap for quantitation. The lower limit of quantitation was 0.4 nmol/L with less than 20% accuracy and precision. The mean hepcidin concentration in sera for controls was 4.6 +/- 2.7 nmol/L, in patients with sickle cell disease, 7.0 +/- 8.9 nmol/L; in patients with end-stage renal disease, 30.5 +/- 15.7 nmol/L; and patients with penetrant hereditary hemochromatosis, 1.4 +/- 0.8 nmol/L.
Plasma and Aqueous Humor Endothelin Levels in Primary Open-Angle Glaucoma (1997)

The small increase in aqueous humor endothelin levels in patients with primary open-angle glaucoma versus controls of similar age may be relevant to the understanding of the various roles of ETs in aqueous humor dynamics in these patients.
Optimal Piecewise Polynomial L<sup>2</sup>Approximation of Functions of One and Two Variables (1975)

The problem of piecewise polynomial L2 approximation with variable boundaries is considered. Necdssary and sufficient conditions for local optima are derived. These suggest simple functional iteration, algorithms for locating the boundaries.
Formation and Evaluation of Derivatives, Preparation and Insecticidal Evaluation of Alcohol and Amine Adducts of Kepone (1966)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTFormation and Evaluation of Derivatives, Preparation and Insecticidal Evaluation of Alcohol and Amine Adducts of KeponeE. E. Gilbert, Pasquale Lombardo, and G. L. WalkerCite this: J. Agric. Food Chem. 1966, 14, 2, 115–116Publication Date (Print):March 1, 1966Publication History Published online1 May 2002Published inissue 1 March 1966https://pubs.acs.org/doi/10.1021/jf60144a005https://doi.org/10.1021/jf60144a005research-articleACS PublicationsRequest reuse permissionsArticle Views52Altmetric-Citations4LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Imiquimod modulates the expression of survivin, bcl-2 and Ki67 in skin tumors (2006)

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High-Q Dielectric Resonator Sintered at Low Firing Temperature (1985)

The microwave properties of dielectric resonators were investigated. The dielectric ceramics with Ba(Mg, Co) 1/3 Nb 2/3 O 3 -Ba(Co 1/3 Ta 2/3 )O 3 system were found to be fired at a low temperature below 1400°C and to have high- ε r and high-Q value. Dielectric properties at microwave frequency were measuered. Dielectric properties of the ceramic resonator were dielectric constant of 31, the Q-value of 10000 at 10 GHz. The temperature dependence of resonant frequency was 0.25 ppm/°C from -40°C to 100°C.
413. Vasicine (1932)

T. P. Ghose, S. Krishna, K. S. Narang and J. N. Rây, J. Chem. Soc., 1932, 2740 DOI: 10.1039/JR9320002740