gebhart/patrepeval huggingface dataset:
Colloidal Surface Active Maghemite Nanoparticles for Biologically Safe Cr<sup>VI</sup> Remediation: from Core‐Shell Nanostructures to Pilot Plant Development (2016)

The present study is aimed at the exploration of achievable improvements for Cr(VI) ex situ and in situ water remediation by using novel naked colloidal maghemite (γ-Fe2 O3 ) nanoparticles (surface active maghemite nanoparticles, SAMNs). The reliability of SAMNs for Cr(VI) binding and removal was demonstrated, and SAMN@Cr(VI) complex was characterized, as well as the covalent nature of the absorption was unequivocally proved. SAMNs were structurally and magnetically well conserved after Cr(VI) binding. Thus, in consideration of their affinity for Cr(VI) , SAMNs were exploited in a biological model system, mimicking a real in situ application. The assay evidenced a progressive reduction of revertant colonies of Salmonella typhimurium TA100 strain, as maghemite nanoparticles concentration increased, till the complete suppression of Cr(VI) mutagen effect. Finally, an automatic modular pilot system for continuous magnetic removal and recovery of Cr(VI) from water is proposed. SAMNs, thanks to their colloidal, binding, and catalytic properties, represent a promising tool as a reliable nanomaterial for water remediation by Cr(VI) .
A new test stand for dynamically testing coupon samples (2003)

Get PDF Email Share Share with Facebook Tweet This Post on reddit Share with LinkedIn Add to CiteULike Add to Mendeley Add to BibSonomy Get Citation Copy Citation Text Y. Zhang, T. D. Milster, J. Butz, and W. Bletcher, "A new test stand for dynamically testing coupon samples," in Optical Data Storage, OSA Technical Digest Series (Optica Publishing Group, 2003), paper TuE39. Export Citation BibTex Endnote (RIS) HTML Plain Text Citation alert Save article
Sparsomycin (1967)

Sparsomycin is one of the antibiotics produced by Streptomyces sparsogenes var. sparsogenes (Owen, Dietz and Camiener, 1962). It has been isolated as crystalline material from the culture filtrates and has the molecular formula C31H21N3O6S2 (Argoudelis and Herr, 1962) but its structure is not yet known.
Moulding and shielding flexural waves in elastic plates (2014)

International audience
An Analysis of Micro Aeroelastic Energy Harvesting Devices (2009)

New micro renewable energy harvesting devices are being developed using the stable limit cycle response of aeroelastic systems to drive energy conversion. This paper analyzes such devices. This paper investigates devices that use two types of aeroelastic instability: galloping and multi-mode flutter. Since the generation of power can be stabilizing, resulting in no power generation at all, the analysis begins by analyzing the stability of such devices from the perspective of power generation. Next, the level of power generation is discussed, and peak levels of performance are found. The analysis suggests that with proper tuning the power generation of micro aeroelastic energy harvesters operating at representative speeds (∼4.5 m/s (10 mph)) can produce power on the order of 10 mW.
[Comparative analysis on chemical constituents in Bupleurum chinense,B. marginatum,B. marginatum var. stenophyllum and B. smithii var. parvifolium]. (2019)

UPLC-Q-TOF-MS was used to analyze the chemical differences in Bupleurum. chinense,B. marginatum,B. marginatum var. stenophyllum and B. smithii var. parvifolium. Chromatographic separation was carried out on an Acquity HSS T3 C_(18) column( 2. 1 mm ×100 mm,1. 8 μm,Waters) with the mobile phase composed of 0. 1% formic acid in water-acetonitrile in the gradient elution. A hybrid quadrupole time-of-flight tandem mass spectrometry( Q-TOF-MS~E) was used for mass spectrometric analysis. Finally,25 peaks were identified based on their exact mass data and fragmentation characteristics. B.chinense,B.marginatum,B. marginatum var. stenophyllum and B. smithii var. parvifolium were obviously clustered into 3 types through processing by principal component analysis( PCA). There was almost no difference between B. chinense and B. marginatum. However,the compounds existed in B. chinense were different from those in B. marginatum var. stenophyllum,and B. smithii var. parvifolium.
The signal peptide sequence of a lytic transglycosylase of Neisseria meningitidis is involved in regulation of gene expression (2004)

The 60 nucleotides encoding the signal peptide of the Neisseria meningitidis membrane-bound lytic transglycosylase (MltA) homologue GNA33 were found to exert a negative regulatory effect on expression of GNA33 from either a T7- or a P(lac)-driven system in Escherichia coli. Down-regulation was observed to occur at the transcriptional/post-transcriptional level and could possibly be ascribed to the formation of a stem-loop secondary structure within the signal peptide sequence. Slowing down the transcription rate through inhibition/titration of the RNA polymerase resulted in a considerable increase in mRNA accumulation, suggesting that a better coupling of translation to transcription would impede the formation of the putative secondary structure. Screening of synonymous mutations in the signal peptide sequence that showed high-level expression of an in-frame fusion to a reporter resulted in the isolation of several deletion mutants lacking most of the sequence participating in the putative secondary structure. Interestingly, the increase in the steady-state mRNA level observed in deletion mutants was higher, reaching a 300-fold increment, than that found in substitution mutants. Our results support the hypothesis that the rate of transcription controls the formation of a secondary structure in the region of the GNA33 transcript corresponding to the signal peptide sequence and this, when formed, negatively regulates expression.
Long‐term outcome of primary non‐responders to tenofovir therapy in <scp>HIV</scp>/<scp>HBV</scp>‐co‐infected patients: impact of <scp>HBV</scp> genotype G (2011)

In these HBV/HIV-co-infected patients, first-line HBV therapy with tenofovir and emtricitabine or lamivudine was associated with EVR. However, DR to tenofovir was observed in 15% of patients who added tenofovir to lamivudine therapy, of whom four of seven (57%) had genotype G-HBV infection. No resistance was evidenced after 46 months of therapy even in patients with DR to tenofovir. At last, a good renal safety profile of TDF was observed after a median follow-up of 4 years of therapy.
TEXTURAL CHARACTERIZATION OF TEMPERATURE SENSITIVE FOODS (1975)

Abstract The instrumental texture profile method is extended to include the temperature variant. Using dessert gel systems and whipped toppings as examples of thermally sensitive foods, advantages are demonstrated of performing instrumental measurements at a series of ascending temperatures covering the range that would be encountered during sensory evaluation. Plotting instrumental values against temperature yields curves which, for different samples within a product system, cross each other at different points and exhibit different rates of change. Advantages are also demonstrated of using several complementary instruments to obtain a more complete characterization. The Texturometer, the Gel Characterization Apparatus and the Brookfield Viscometer were used with the gel systems. In addition, the Texture Test System fitted with an orifice attachment and the Cenco Calorimeter were used with whipped toppings. Correlations with sensory evaluations using the texture profiling system are reported.
Histidine-Rich Peptide Selection and Quantification in Targeted Proteomics (2003)

Agarose based immobilized copper (II) affinity chromatography (Cu(II)-IMAC) in tandem with reversed-phase chromatography was applied to a yeast protein extract. Histidine-rich peptides were selected and, in the process, samples were substantially simplified prior to mass spectral analysis. Samples of proteins from the yeast extract at fermentation time periods of 2.5 and 10 h were compared quantitatively used the GIST protocol. Acylation of the N-terminus of tryptic peptides with N-acetoxysuccinamide was used to globally label and quantify relative protein concentration changes. Together with N-terminal acylation, an imidazole elution procedure allowed histidine-rich peptides to be preferentially selected by Cu(II)-IMAC. An inverse labeling strategy was applied to increase reliability in determinations of up- and down-regulation. It was found that the concentration of some histidine-rich proteins changed in excess of 4-fold during fermentation. These proteins covered a wide range of molecular weight and pI values.
Introduction: food from microbes (1980)

Humanity faces great challenges in the years ahead. Prospects for the future include an even higher incidence of hunger, starvation, and malnutrition in the world. Producing food from microbes may significantly alleviate some of these problems. The earth's population will certainly increase by at least 50% to a total of 6 billion people by the end of this century. It will likely double to 8 billion in the 21st century. Large cities such as Mexico City, Sao Paulo, and Calcutta will, by the year 2000, have populations of 30 million, 26 million, and 16 million, respectively (Blume 1979).
Mechanisms of Oncogene Cooperation: Activation and Inactivation of a Growth Antagonist (1991)

Gene transfer experiments have defined limitations with regard to the ability of individual oncogenes to transform cultured cells to a tumorigenic state. The stable transformation of REF52 cells by either the ras or sis oncogenes requires the continuous expression of a second collaborating oncogene, such as adenovirus-5 E1A or SV40 large T-antigen. Our studies suggest that the function of the nuclear collaborators is to antagonize dominant growth controls which limit the ability of REF52 cells to proliferate in response to mitogenic stimuli.
The transmembrane segment of invariant chain mediates binding to MHC class II molecules in a CLIP-independent manner (2001)

Invariant chain (Ii) association with MHC class II molecules is strongly dependent upon interaction of CLIP (Ii exon 3, residues 81 - 104) with the peptide binding groove of the class II dimer. This dominant interaction does not adequately explain, however, the efficient association of Ii with class II molecules of diverse allelic and isotypic origin, which have markedly different affinities for synthetic peptides corresponding to CLIP. In agreement with other recent observations, we demonstrate here that class II molecules with occupied binding sites unable to engage CLIP maintain association with Ii in mild detergent. The association is direct and not mediated through unoccupied class II chains bound to properly assembled and loaded class II dimers, nor is it mediated through chaperones. The site of this CLIP-independent binding has been mapped using truncation mutants and an Ii-human transferrin receptor chimeric protein to the transmembrane segment of Ii. The existence of multiple low-affinity sites of interaction between MHC class II and Ii helps explain how effective occupancy of all newly synthesized class II molecules can occur despite substantial variations in the strength of CLIP-dependent association that arise from class II binding domain polymorphism. These data establishing a site of Ii-MHC class II association N-terminal to CLIP also provide new insight into the possible functional relationship between the sequential endocytic proteolysis of Ii from its C terminus and a series of contact sites with MHC class II molecules spread from the transmembrane region through to the tip of the lumenal segment of Ii.
In-flight load testing of advanced shuttle thermal protection systems (1983)

NASA Ames Research Center has conducted in-flight airload testing of some advanced thermal protection systems (TPS) at the Dryden Flight Research Center. The two flexible TPS materials tested, felt reusable surface insulation (FRSI) and advanced flexible reusable surface insulation (AFRSI), are currently certified for use on the Shuttle orbiter. The objectives of the flight tests were to evaluate the performance of FRSI and AFRSI at simulated launch airloads and to provide a data base for future advanced TPS flight tests. Five TPS configurations were evaluated in a flow field which was representative of relatively flat areas without secondary flows. The TPS materials were placed on a fin, the Flight Test fixture (FTF), that is attached to the underside of the fuselage of an F-104 aircraft. This paper describes the test approach and techniques used and presents the results of the advanced TPS flight test. There were no failures noted during post-flight inspections of the TPS materials which were exposed to airloads 40 percent higher than the design launch airloads.
Insect-Resistant Transgenic Crops Expressing Plant Lectins (2004)

USDA-ARS-CMAVE, Center for Biological Control, Florida A&M University Tallahassee, FL 32307, USA; *Department of EntomologyINTRODUCTION Transgenic insecticidal crop cultivars are in the process of revolutionizing agriculture and are likely to become a major insect management tactic worldwide. Introducing novel resistance genes into economically-important crops can develop insect-resistant crops. This tactic has a potentially key role in integrated pest management of several important pests (Gatehouse and Gatehouse, 1998). Most of the research and development thus far has focused on the transfer of genes expressing toxins produced by the soil-borne bacterium, Bacillus thuringiensis (Berliner) (Bt) into food, grain and fiber plants. The insecticidal Bt dendotoxins are a family of related proteins with different levels of activity against species of Lepidoptera, Coleoptera and Diptera (see Vaeck et al., 1987). Bt-transgenic cultivars have been produced for tobacco (Nicotiana tabacum), potato (Solanum tuberosum), cotton (Gossypium hirsutum), maize (Zea mays), rice (Oryza sativa), tomato (Lycopersicon esculentum), broccoli (Brassica oleracea botrytis), alfalfa (Medicago sativa) and other crops (Hilder and Boulter, 1999). In March 2000, Bt maize and Bt cotton each comprised 18% of the total acreages^Contact through senior authorplanted to these crops in the USA (USDA ERS, 2000). These acreages are expected to increase dramatically in the near future, both in developed and developing countries (Carozzi and Koziel, 1997; Gould, 1998). Field evaluations of Bt transgenic cultivars have produced mixed results. Effective pest suppression was reported for Bt cotton against cotton bollworm, Helicoverpa zea (Boddie) (Lepidoptera: Noctuidae) and pink bollworm, Pectinophora gossypiella (Saunders) (Lepidoptera: Gelechiidae), Bt potato against Colorado potato beetle, Leptinotarsa decemlineata (Say) (Coleoptera: Chrysomelidae), and Bt maize against European corn borer, Ostrinia nubilalis (Hiibner) (Lepidoptera: Pyralidae) (Hilder and Boulter, 1999). However, the failure of the 800,000 ha. planted with Bt cotton against H. zea and P. gossypiella was widely reported in 1996. Furthermore, Bt cotton was also reported to have failed against H. armigera (Hiibner) in Australia (Hilder and Boulter, 1999).
Atypical Measles Syndrome: Pathologic and Serologic Findings (1982)

The clinical course of measles occurring in 17 adolescents who had previously received killed measles vaccine is described. All adolescents had a peripheral dermatitis. Fifteen had characteristic pulmonary infiltrates. Serologic study in six adolescents using immunoprecipitation of 35S-methionine-labeled measles virus antigens revealed that 5/6 acute sera lacked antibody to the hemolysin antigen whereas 5/6 sera contained antibody to hemagglutinin antigen. Skin biopsies, obtained from three patients, demonstrate a combination of an Arthus reaction and delayed hypersensitivity. The typical measles histologic complex was absent. Measles virions were seen in the deep dermal blood vessels. The serologic and histopathologic presentation of this disease indicates that killed vaccine does not adequately induce antibody to the hemolysin (F) which is necessary to prevent cell-to-cell spread of paramyxoviruses. Killed vaccine does, however, produce hemagglutinin antibody and simultaneously incites later hypersensitivity to wild virus infection, producing the unusual dermatopathologic reaction seen.
ChemInform Abstract: Anion‐Molecule Approaches to Non‐Kekule Molecules: The Radical Anion of Cyclopentadienylidenetrimethylenemethane and Derivatives. (1997)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Polyphasic Taxonomy of the Genus<i>Vibrio:</i>Numerical Taxonomy of<i>Vibrio cholerae, Vibrio parahaemolyticus</i>, and Related<i>Vibrio</i>Species (1970)

A set of 86 bacterial cultures, including 30 strains of Vibrio cholerae, 35 strains of V. parahaemolyticus, and 21 representative strains of Pseudomonas, Spirillum, Achromobacter, Arthrobacter, and marine Vibrio species were tested for a total of 200 characteristics. Morphological, physiological, and biochemical characteristics were included in the analysis. Overall deoxyribonucleic acid (DNA) base compositions and ultrastructure, under the electron microscope, were also examined. The taxonomic data were analyzed by computer by using numerical taxonomy programs designed to sort and cluster strains related phenetically. The V. cholerae strains formed an homogeneous cluster, sharing overall S values of >/=75%. Two strains, V. cholerae NCTC 30 and NCTC 8042, did not fall into the V. cholerae species group when tested by the hypothetical median organism calculation. No separation of "classic" V. cholerae, El Tor vibrios, and nonagglutinable vibrios was observed. These all fell into a single, relatively homogeneous, V. cholerae species cluster. V. parahaemolyticus strains, excepting 5144, 5146, and 5162, designated members of the species V. alginolyticus, clustered at S >/=80%. Characteristics uniformly present in all the Vibrio species examined are given, as are also characteristics and frequency of occurrence for V. cholerae and V. parahaemolyticus. The clusters formed in the numerical taxonomy analyses revealed similar overall DNA base compositions, with the range for the Vibrio species of 40 to 48% guanine plus cytosine. Generic level of relationship of V. cholerae and V. parahaemolyticus is considered dubious. Intra- and intergroup relationships obtained from the numerical taxonomy studies showed highly significant correlation with DNA/DNA reassociation data.
GOES: Girls in Ocean Engineering and Science Institute (2019)

The GOES: Girls in Ocean Engineering and Science program encourages rising 6 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">th</sup> grade girls to consider careers in science and engineering. Through a hands-on 4-day summer program, the students learn engineering through design and building activities and learn about the ocean by exploring the natural environment.
High OSNR and simple configuration dual-wavelength fiber laser with wide tunability in S+C+L band (2017)

A simple configuration dual-wavelength fiber laser, by combining the first-order Brillouin laser and the residual pump laser, is proposed and experimentally demonstrated. A 1 km long single-mode fiber is used as the stimulated Brillouin scattering gain medium pumped by a narrow linewidth tunable laser source (TLS). Through simply adjusting the TLS output power, power-equalized dual-wavelength lasing can be achieved with a high optical signal to noise ratio (OSNR) of >80 dB. With the good tunability of the TLS, the dual-wavelength fiber laser has a tunable range of ∼130 nm, and simultaneously the beat frequency of the two lasing wavelengths can be tuned from 10.1875 to 11.0815 GHz with the tunable range of 0.8940 GHz. The high stability of the dual-wavelength operation is experimentally verified by the measured beat frequency fluctuation of ≤6 MHz in 1 h and power fluctuation of ≤0.03 dB in 2 h. The temporal characteristics of the fiber laser are also investigated experimentally. The fiber laser will find good applications in fiber sensing and microwave photonics areas.
Improvements in the realization of fiber slanted gratings (1999)

Slanted gratings are becoming very attractive components for dense WDM systems because they can be used as optical fibre filters to flatten the gain spectrum of erbium doped fiber amplifiers. Up to now, limits of such filters are the residual fibre Bragg grating reflectivity and the temperature sensitivity of the component. In this report, we demonstrate improvements in the realization of slanted grating in photosensitive cladding fiber with very low back reflection. Results concerning their thermal stability are also discussed. (4 pages)
Immunogenic activity of gonococcal protein I in mice with three different lipoidal adjuvants delivered in liposomes and in complexes (1986)

For several reasons the major outer membrane protein from Neisseria gonorrhoeae (gonococcal protein [PI]) is an attractive component for a gonococcal vaccine. This paper describes the influence of two different physical forms of PI on its immunogenic activity. To this end PI was delivered in liposomes and in protein-detergent complexes. In both forms PI was present in a multimeric form. The liposomes were composed of phosphatidylcholine and cholesterol. The effect of dicetylphosphate as a negatively charged amphiphile and three lipoidal adjuvants was investigated. Two lipoidal adjuvants (Avridine and dimethyldioctadecylammoniumbromide) were positively charged amphiphiles, whereas the third one (tridecyl N-acetylmuramyl-L-alanyl-D-isoglutaminate) was neutral. The protein-detergent complexes were also tested in the presence of the lipoidal adjuvants and in an AlPO4-adsorbed form. The liposome preparations were characterized for their size, charge, and residual amount of detergent. The immunogenic activity of PI in all forms was tested in mice. The results of the antibody assays showed that PI in the liposomes was more immunogenic than PI in the complexes. A second dose with liposomes induced only a small booster effect, whereas such a dose with the complexes produced pronounced booster effects. The incorporation of the positively charged lipoidal adjuvants in the liposomes resulted in enhanced booster effects. The highest immunogenic activity of PI after two injections, however, was observed in the complexed form adsorbed to AlPO4.
Design of High Speed Transmission Systems over Unshielded Twisted Pair Cables (2002)

This chapter contains sections titled: Design of a Quaternary Partial Response Class-IV System for Data Transmission at 125 Mbit/s Design of a Dual Duplex Transmission System at 100 Mbit/s Bibliography Appendix 19.A: Interference Suppression
Excess circulating angiopoietin-2 is a strong predictor of mortality in critically ill medical patients (2008)

A marked imbalance of the Ang-Tie system in favour of Ang-2 is present in critically ill medical patients. Our findings highlight the independent prognostic impact of circulating Ang-2 in critical illness. Ang-2 may be used as a readily available powerful predictor of outcome and may open new perspectives to individualise treatment in the ICU.
Position Control for Non-linear, Multiple-Link Robots (1987)

Several approaches to complicated control problem examined. Report surveys methods for controlling motion of robot manipulators. Applies to coupled, highly nonlinear multiple-link robots. Presents adaptive control technique based on discrete linear model of robot arm, obtained by linearizing nonlinear dynamical equations about nominal trajectory. Parameters of model calculated with adaptive parameter-identification algorithm. Based on system model, optimal control input computed using position and velocity feedback.