gebhart/patrepeval huggingface dataset:
The effectiveness of hand cooling at reducing exercise-induced hyperthermia and improving distance-race performance in wheelchair and able-bodied athletes (2008)

The purpose of this study was to examine the effectiveness of reducing core temperature in postexercise hyperthermic subjects and to assess if hand cooling (HC) improves subsequent timed distance performance. Following a detailed measurement check on the use of insulated auditory canal temperature (T(ac)), eight wheelchair (WA) athletes and seven male able-bodied (AB) athletes performed two testing sessions, comprising a 60-min exercise protocol and 10-min recovery period, followed by a performance trial (1 km and 3 km for WA and AB, respectively) at 30.8 degrees C (SD 0.2) and 60.6% (SD 0.2) relative humidity. In a counterbalanced order, HC and a no-cooling condition was administered during the 10-min recovery period before the performance trial. Nonsignificant condition x time interactions for both WA (F(15,75) = 1.5, P = 0.14) and AB (F(15,90) = 1.2, P = 0.32) confirmed that the exercise-induced changes (Delta) in T(ac) were similar before each intervention. However, the exercise-induced increase was evidently greater in AB compared with WA (2.0 vs. 1.3 degrees C change, respectively). HC produced DeltaT(ac) of -0.4 degrees C (SD 0.4) and -1.2 degrees C (SD 0.2) in comparison (WA and AB, respectively), and simple-effects analyses suggested that the reductions in T(ac) were noteworthy after 4 min of HC. HC had an impact on improving AB performances by -4.0 s (SD 11.5) (P < 0.05) and WA by -20.5 s (SD 24.2) (P > 0.05). In conclusion, extraction of heat through the hands was effective in lowering T(ac) in both groups and improving 3-km performance in the AB athletes and trends toward positive gains for the 1-km performance times of the WA group.
A spiking neural network architecture for nonlinear function approximation (2003)

Multilayer perceptrons have received much attention due to their universal approximation capabilities. Normally such models use real valued signals, although they are loosely based on biological neuronal networks which encode signals using spike trains. Spiking neural networks are of interest from both a biological point of view, but also from a method of robust signalling in particularly noisy or difficult environments. From a signal processing perspective, it is important to consider networks based on spike trains. A basic question that needs to be considered, is what type of architecture can be used to provide universal function approximation capabilities in spiking networks? We propose a spiking neural network architecture using both integrate and fire units as well as delays which is capable of approximating a real valued function mapping to within a finite degree of accuracy.
Phosphorylation of elongation factor-2 kinase on serine 499 by cAMP-dependent protein kinase induces Ca2+/calmodulin-independent activity (2001)

Elongation factor-2 kinase (eEF-2K) negatively regulates mRNA translation via the phosphorylation and inactivation of elongation factor-2 (eEF-2). We have shown previously that purified eEF-2K can be phosphorylated in vitro by cAMP-dependent protein kinase (PKA) and that this induces significant Ca2+/calmodulin (CaM)-independent eEF-2K activity [Redpath and Proud (1993) Biochem. J. 293, 31–34]. Furthermore, elevation of cAMP levels in adipocytes also increases the level of Ca2+/CaM-independent eEF-2K activity to a similar extent, providing a mechanistic link between elevated cAMP and the inhibition of protein synthesis [Diggle, Redpath, Heesom and Denton (1998) Biochem. J. 336, 525–529]. Here we describe the expression of glutathione S-transferase (GST)-eEF-2K fusion protein and the identification of two serine residues that are phosphorylated by PKA in vitro. Endoproteinase Arg-C digestion of GST-eEF-2K produced two phosphopeptides that were separated by HPLC and sequenced. 32P Radioactivity release from these peptides indicated that the sites of phosphorylation were Ser-365 and Ser-499, both of which lie C-terminal to the catalytic domain. Mutation of these sites to non-phosphorylatable residues indicated that both sites need to be phosphorylated to induce Ca2+/CaM-independent eEF-2K activity in vitro. However, expression of Myc-tagged eEF-2K in HEK 293 cells, followed by treatment with chlorophenylthio-cAMP (CPT-cAMP), showed that Ser-499 phosphorylation alone induced Ca2+/CaM-independent eEF-2K activity in cells. Co-expression of wild-type eEF-2K with luciferase resulted in a 2–3-fold reduction in luciferase expression. Expression of eEF-2K S499D resulted in a 10-fold reduction in luciferase expression despite the fact that this mutant was expressed at very low levels. This indicates that eEF-2K S499D is constitutively active when expressed in cells, thus leading to the suppression of its own expression. Our data demonstrate an important role for the phosphorylation of Ser-499 in the activation of eEF-2K by PKA and the inhibition of protein synthesis.
Role of Hemostatic Risk Factors for Restenosis in Peripheral Arterial Occlusive Disease After Transluminal Angioplasty (1997)

In a prospective study, the role of various hemostatic factors known to be associated with thrombotic risk was investigated in 71 patients with peripheral arterial occlusive disease (PAOD, stages II through IV, Fontaine; aged 68 +/- 13 years). Laboratory investigations were done before; 1, 24, and 48 hours after; and 3 and 6 months after percutaneous transluminal angioplasty (PTA). Thirty of 71 (42.3%) patients developed restenosis (> 50% reduction of the lumen diameter) at the site of PTA within 6 months, verified by color-coded duplex sonography. Significantly increased levels of thrombin-antithrombin III complexes (P < .01), prothrombin fragments 1 + 2 (P < .01), and D-dimers (P < .01) were found 1 hour, as well as 24 to 48 hours, after PTA. Fibrinogen (P < .01) and von Willebrand factor (P < .01) were significantly higher 48 hours after PTA. Restenotic patients as a whole had higher plasma fibrinogen (3.46 +/- 1.12 versus 2.95 +/- 0.62 g/L, P < .01) and C-reactive protein (25.4 +/- 46.7 versus 7.9 +/- 6.9 mg/L, P < .05) at baseline, as well as higher fibrinogen (P < .05) and prothrombin fragments 1 + 2 (P < .01) during months 3 to 6 after PTA. There was a nonsignificant tendency for higher values of von Willebrand factor (206 +/- 98% versus 184 +/- 100%, P = .2) at baseline in patients with restenosis, whereas tissue plasminogen activator, plasminogen activator inhibitor, coagulation screening tests, blood cell counts, and serum lipids showed no significant difference between the two groups. The relative risk for developing restenosis within 6 months while having high fibrinogen (> 2.8 g/L) or C-reactive protein at baseline was 2.80 (95% CI: 1.30-6.02, P < .01) and 1.96 (95% CI: 1.07-3.58, P < .05), respectively. Patients with critical limb ischemia (stage III/IV, Fontaine) had significantly higher fibrinogen and von Willebrand factor at repeated points of time, as well as significantly higher C-reactive protein and lower creatinine clearance at entry. In the logistic regression risk factor analysis, baseline plasma fibrinogen, C-reactive protein concentration, and the severity of the arterial disease were significantly predictive of restenosis. Our results indicate that high procoagulant factors and persistent thrombin generation of the hemostatic system might promote restenosis, particularly in patients with extended atherosclerosis. This finding suggests that new treatment strategies should be taken under consideration for patients with PAOD and PTA.
Nitrosodisulphonates. Part I. Fremy's salt (potassium nitrosodisulphonate) (1968)

Solid potassium nitrosodisulphonate (Fremy's Salt) is shown to exist in two distinct crystalline forms. An improved preparation, and crystallisation methods for both forms are given. Stability of both solids and solution is discussed in detail. The forms are compared in terms of their i.r. spectra, magnetic properties, X-ray powder patterns, and unit cells.
Studies on Clot Density (1952)

Journal Article Studies on Clot Density Get access Bruno W. Volk, M.D., Bruno W. Volk, M.D. From the Division of Laboratories and the Department of Medicine, Jewish Sanitarium and Hospital for Chronic Diseases, Brooklyn, New York Search for other works by this author on: Oxford Academic Google Scholar Samuel Losner, M.D., Samuel Losner, M.D. From the Division of Laboratories and the Department of Medicine, Jewish Sanitarium and Hospital for Chronic Diseases, Brooklyn, New York Search for other works by this author on: Oxford Academic Google Scholar Mendel Jacobi, M.D., Mendel Jacobi, M.D. From the Division of Laboratories and the Department of Medicine, Jewish Sanitarium and Hospital for Chronic Diseases, Brooklyn, New York Search for other works by this author on: Oxford Academic Google Scholar Sydney S. Lazarus, M.D. Sydney S. Lazarus, M.D. From the Division of Laboratories and the Department of Medicine, Jewish Sanitarium and Hospital for Chronic Diseases, Brooklyn, New York Search for other works by this author on: Oxford Academic Google Scholar American Journal of Clinical Pathology, Volume 22, Issue 2, 1 February 1952, Pages 99–106, https://doi.org/10.1093/ajcp/22.2.99 Published: 01 February 1952 Article history Received: 12 October 1951 Published: 01 February 1952
Recommended Approaches for the Laboratory Measurement of Homocysteine in the Diagnosis and Monitoring of Patients with Hyperhomocysteinaemia (1999)

Several recent studies have indicated that an increased concentration of plasma homocysteine is an independent risk factor for the premature development of vascular disease. These important findings emphasize the need for careful selection of an appropriate analytical approach to diagnose and treat individuals who may be at risk. We compared the results obtained from the measurement of plasma total homocysteine (free + protein-bound fractions) by high-performance liquid chromatography (HPLC) with the measurement of plasma free homocystine (free fraction) by conventional ion-exchange chromatography in 10 patients with inherited defects of homocysteine metabolism and 13 obligate heterozygote individuals. This study can be used to formulate recommendations on the appropriate use of these assays in different clinical circumstances. Our results show that the concentration of total plasma homocysteine must exceed 60 mumol/L before plasma free homocystine becomes detectable by conventional ion-exchange chromatography. Similarly, assessment of the urinary excretion of homocysteine in these patients indicates that it may not become consistently detectable by conventional ion-exchange chromatography or HPLC until plasma total homocysteine exceeds 150 mumol/L. On this basis, while most patients with classical homocystinuria would be detected by analysis of plasma using conventional ion-exchange chromatography or by measurement of of the urinary homocysteine excretion, occasional patients would be missed. When monitoring patients receiving treatment for classical homocystinuria, in whom metabolic control is good, and when investigating individuals with a suspected inherited defect of cobalamin or folate metabolism, a method which measures plasma total homocysteine should be used. The identification of moderate hyperhomocysteinaemia of undefined cause investigated in relation to a history of early vacsular disease can only be identified by this approach.
The CLICK (CSIRO Laboratory for Imaging by Content and Knowledge) Security Demonstrator (2002)

CSIRO Telecommunications and Industrial Physics is developing digital image processing tools using object oriented technology on a PC platform, with an emphasis on the study of image content and the application of domain knowledge. This paper summarises progress made in the following areas: (a) image database browsing, (b) real-time face recognition and verification, and (c) still image and video compression. The focus of the paper is on security applications of these technologies which have been integrated into the CLICK (CSIRO Laboratory for Imaging by Content and Knowledge) Security Demonstrator.
Coverage-Based Test Case Prioritisation: An Industrial Case Study (2013)

This paper presents an industrial case study of coverage-based prioritisation techniques on a real world system with real regression faults. The study evaluates four common and different test case prioritisation techniques and examines the effects of using various coverage criteria on the fault detection rates of the prioritised test suites. The results show that prioritisation techniques that are based on additional coverage with finer grained coverage criteria perform significantly better in fault detection rates. The study also reveals that using modification information does not significantly enhance fault detection rates.
Remarks Suggested by Fascist Humanism and the Enemy Enlightenment (1973)

For mankind in the total orphanage which is this world homeostasis is well served by the diverse learning—as knowledge and as process—with which the members of the Modern Language Association of America are professionally concerned: language as communication and rhetoric, literature as a means of heightened understanding, and the systematic study of these relevant areas of knowledge in the interest of effective instruction in them.
Teach network class over Internet using browser-based technologies (2003)

The author has developed a data communications and communication networks class for online offering over the Internet. The password protected class Web site contains all the teaching materials including the syllabus, assignments, simulation software, multimedia documents and Powerpoint lecture notes. The instructor led the class discussions with the students and answered their questions on the Internet either asynchronously through the bulletin board, email, file transfer, remote login and HTML/CGI forms; or synchronously through the chat rooms using multimedia software tools with a video camera. Students have had a flexible learning environment with a browser-based interface. The author believes that this course has provided both the instructor and students a much-needed platform to study and explore the pedagogy of the online teaching on the Internet.
Factorization Bandits for Interactive Recommendation (2017)

We perform online interactive recommendation via a factorization-based bandit algorithm. Low-rank matrix completion is performed over an incrementally constructed user-item preference matrix, where an upper confidence bound based item selection strategy is developed to balance the exploit/explore trade-off during online learning. Observable contextual features and dependency among users (e.g., social influence) are leveraged to improve the algorithm's convergence rate and help conquer cold-start in recommendation. A high probability sublinear upper regret bound is proved for the developed algorithm, where considerable regret reduction is achieved on both user and item sides. Extensive experimentations on both simulations and large-scale real-world datasets confirmed the advantages of the proposed algorithm compared with several state-of-the-art factorization-based and bandit-based collaborative filtering methods.
Several Problems on the Heavy Oil Combustion (1959)

SYNOPSIS: -The author describes several problems on the combustion of heavy oil from results of his studies and some references. The items reviewed are as follows:1) The combustion velocity and growing heat in the heavy oil combustion.2) The influences of fuel's properties upon the spray size of fuel and the deposition of carbon.3) The microgram quantity of contents in fuel as catalyst in the heavy oil combustion.4) The corrosion by vanadium and sulfer in fael.
Dissipation in Solid-State Devices--The Magic of Il + N (1976)

The current capacity of a solid-state device, as ordinarily rated, varies widely depending on the current waveform, duty cycle, case temperature, etc. The underlying junction temperature limits should, however, be invariant.
Case 16-2007 (2007)

A 61-year-old man was referred to the thoracic oncology service for management of a thymoma. Six weeks earlier, a mediastinal mass, 4 cm in diameter, had been detected on a computed tomographic scan obtained because of chest pain. A positron-emission tomographic scan showed increased tracer uptake in the area of the lesion. Biopsy specimens showed a World Health Organization type B1 thymoma. Physical examination was normal. A decision on management was made.
Basic Overview on Gas Chromatography Columns (2015)

Abstract The main purpose of this chapter is to give a basic overview on the basic components of stationary phases/columns in gas chromatography ( GC ) for the benefit of students and beginners in the field of GC .
Introduction to Time-Frequency and Wavelet Transforms (2001)

1. Introduction. 2. Fourier Transform A Mathematical Prism. Frame. Fourier Transform. Relationship between Time and Frequency Representations. Characterization of Time Waveform and Power Spectrum. Uncertainty Principle. Discrete Poisson-Sum Formula. Short-Time Fourier Transform and Gabor Expansion. 3. Short-Time Fourier Transform. Gabor Expansion. Periodic Discrete Gabor Expansion. Orthogonal-Like Gabor Expansion. A Fast Algorithm for Computing Dual Functions. Discrete Gabor Expansion. 4. Linear Time-Variant Filters. LMSE Method. Iterative Method. Selection of Window Functions. 5. Fundamentals of theWavelet Transform. Continuous Wavelet Transform. Piecewise Approximation. Multiresolution Analysis. Wavelet Transformation and Digital Filter Banks. Applications of the Wavelet Transform. 6. Digital Filter Banks andtheWavelet Transform. Two-Channel Perfect Reconstruction Filter Banks. Orthogonal Filter Banks. General Tree-Structure Filter Banks and Wavelet Packets. 7. Wigner-Ville Distribution. Wigner-Ville Distribution. General Properties of the Wigner-Ville Distribution. Wigner-Ville Distribution for the Sum of Multiple Signals. Smoothed Wigner-Ville Distribution. Wigner-Ville Distribution of Analytic Signals. Discrete Wigner-Ville Distribution. 8. Other Time-Dependent Power Spectra. Ambiguity Function. Cohens Class. Some Members of Cohens Class. Reassignment. 9. Decomposition of the Wigner-Ville Distribution. Decomposition of the Wigner-Ville Distribution. Time-Frequency Distribution Series. Selection of Dual Functions. Mean Instantaneous Frequency and Instantaneous Bandwidth. Application for Earthquake Engineering. 10. Adaptive Gabor Expansion and Matching Pursuit. Matching Pursuit. Adaptive Gabor Expansion. Fast Refinement. Applications of the Adaptive Gabor Expansion. Adaptive Gaussian Chirplet Decomposition. Optimal Dual Functions. Bibliography. Index.
Application of MIMO and proportional fair scheduling to CDMA downlink packet data channels (2003)

There are many capacity enhancement techniques in wireless networks. Multiple-input-multiple-output (MIMO) antenna systems, channel-state based packet data scheduling algorithms and adaptive modulation and coding are examples of such techniques. In this paper, we provide the simulation results for various transmission schemes (including MIMO) in conjunction with a channel-state-based scheduling algorithm and an adaptive modulation and coding scheme Consequently, we demonstrate the cellular system capacity gain resulting from interaction between these three techniques. Specifically, system-level simulations are presented for the wideband CDMA (WCDMA) downlink shared channel.
Diffusion and field-gradient effects in NMR Fourier spectroscopy (1974)

In NMR Fourier transform spectroscopy, rf pulses are periodically applied to a spin system to generate a sequence of free induction decays which form the basis of spectroscopic measurements. In inhomogeneous magnetic fields, distortions of the free induction decay arise from superimposed spin-echo effects. They are strongly dependent on molecular diffusion which is also responsible for the nonexponential envelope of the echo train observed in a stopped pulse experiment. These effects are investigated by means of two independent methods, the Fourier expansion method and the partition method. The results are discussed and used to explain measurements made on a one-spin system. The influence of echoes on the sensitivity of Fourier transform spectroscopy is considered, and it is concluded that the achievable gain does not normally outweigh the complications arising from retention or enhancement of echoes. Experimental parameters are derived for efficient suppression of echoes by means of a periodically pulsed magnetic field gradient.
Purification of a Protein from Culture Filtrates of<i>Fusarium oxysporum</i>that Induces Ethylene and Necrosis in Leaves of<i>Erythroxylum coca</i> (1995)

Culture filtrates of Fusarium oxysporum elicited ethylene production and necrosis when applied to leaves of Erythroxylum coca. A protein that induces ethylene production and necrosis in leaves of E. coca was purified from culture filtrates of an isolate of F. oxysporum pathogenic to E. coca. The protein was first concentrated using ultrafiltration where it was retained by a 1-kDa filter. The protein was purified by fast protein liquid chromatography using cation exchange chromatography followed by hydrophobic interaction chromatography. Gel filtration was used as the final purification step and to exchange salts. The protein migrated as a single band on sodium dodecyl sulfate-polyacrylamide gels with an estimated molecular mass of 22.5 kDa. The exact mass was determined by mass spectroscopy to be 23,996.1 Da. The mobility of the protein was not affected by reducing agents, but the 24-kDa protein broke down and was inactivated by excessive heat. The protein constituted a major component of the extracellular proteins produced in cultures three or more days old and reached a maximum concentration between 6 and 12 days. Biological activity of the protein could be detected by induction of ethylene down to a concentration of 50 ng per leaf (approximately 500 ng/g fresh weight) when applied as a hanging drop to the petiole of an excised E. coca leaf. The 24-kDa protein induced ethylene biosynthesis and necrosis in a wide variety of Dicotyledoneae, but we were unable to demonstrate activity in members of the Monocotyledoneae tested. It remains to be determined if the 24-kDa protein plays a role in disease development in the F. oxysporum-E. coca interaction.
Involvement of some 5-HT receptors in methamphetamine-induced locomotor activity in mice. (2004)

Effects of some selective 5-HT antagonists on methamphetamine-induced locomotor activity were investigated in male mice in order to study whether this effect of methamphetamine is selectively or at least partially, induced through stimulation of a specific serotonin receptor subtype. Methamphetamine (1.5 mg/kg, IP) produced a significant increase in locomotor activity. Methamphetamine-induced hyperactivity by the above mentioned dose was significantly antagonized by NAN-190 ( 5-HT(1A) antagonist) at a dose of 4 mg/kg, IP, methiothepin (5-HT(1B/1D) antagonist) at a dose of 0.1mg/kg, IP or mianserin ( 5-HT(2C) antagonist) at a dose of 8 mg/kg, IP. On the other hand, methysergide ( 5-HT(2A/2B) antagonist) at a dose of 1mg/kg, IP or ondansetron ( 5-HT(3) antagonist) at a dose of 0.5mg/kg, IP potentiated the methamphetamine-induced hyperactivity. None of the above mentioned doses of 5-HT antagonists altered the spontaneous activity of mice when administered alone. The results of the present study indicate a possible role for serotonergic mechanisms, in addition to the catecholaminergic systems, in the locomotor stimulant activity of methamphetamine in mice. This role is possibly mediated through direct stimulation of some 5-HT receptor subtypes. Stimulation by methamphetamine of 5-HT(1A), 5-HT(1B/1D) and/or 5-HT(2C) receptor subtypes may result in hyperactivity, whereas stimulation by methamphetamine of 5-HT(2A/2B) and/or 5-HT(3) receptor subtypes may result in decreased activity.