gebhart/patrepeval huggingface dataset:
GANA ARTURO VALLEJO EL VIRTUALITY CAZA DE LETRAS (2009)

ARTURO VALLEJO, QUIEN CONCURSO CON EL SEUDONIMO CIENCIA VUDU, GANO EL SEGUNDO VIRTUALITY LITERARIO CAZA DE LETRAS CON LA NOVELA NO TENGO TIEMPO, CUYA TRAMA SE REFIERE A LA VIDA DE UNA JOVEN QUE LABORA EN UN RESTAURANTE DE COMIDA RAPIDA. EL LITERATO RECIBIO RECIENTEMENTE EL MONTO ECONOMICO DEL PREMIO –QUE EQUIVALE A CIEN MIL PESOS– Y ACABA DE ENTREGAR EL ORIGINAL DE SU OBRA A EDITORIAL ALFAGUARA PARA SU PROXIMA PUBLICACION.
Antiaggregatorische und anticoagulante Eigenschaften von Oligoaminen, 12. Mitt.<sup>+)</sup>: Alkyl‐ und Arylalkylderivate von Putrescin, Spermidin und Spermin (1990)

Eleven lipophilic derivatives of the title biogenic amines and 28 structurally related triamines and tetramines have been synthesized. Twenty-three of them inhibited the platelet aggregation induced by collagen at an IC50 between 8 mumol/L and 30 mumol/L. Five compounds prolonged the one stage thromboplastin time (Quick) by 7s or more at 100 mumol/L. The antiplatelet and anticoagulant effect do not run parallel. The relationship between the effects observed and the chemical structure of the oligoamines has been elucidated.
AHP를 활용한 한류관광 활성화 요인 도출과 우선순위 분석 (2015)

본 연구의 목적은 한류관광 활성화를 위한 요인들을 도출하고, 각 요인의 우선순위를 평가하는데 있다. 이러한 연구목적을 달성하기 위하여 본 연구에서는 계층분석적 의사결정과정(AHP: Analytic Hierarchy Process) 방법을 적용하였다. 먼저 본 연구에서는 한류관광 활성화를 최종목표로 하는 계층구조모형을 설정하였고, 한류관광 전문가 25명을 대상으로 AHP 설문조사를 실시하여 자료를 수집하였다. AHP 계층구조는 한류관광상품, 관광서비스품질, 판매/유통채널, 홍보마케팅, 한류관광정책의 5개 상위요인과 총 18개 하위요인으로 구성되었다. AHP 분석결과 상대적 중요도는 상위요인 중 한류관광상품이 가장 중요한 요인으로 나타났으며, 다음으로는 홍보마케팅, 관광서비스품질, 판매/유통채널, 한류관광정책의 순으로 나타났다. 각 요인별 도출된 가중치를 종합하여 하위요인의 최종 우선순위를 분석한 결과, 한류상품의 유형별/테마별/가격대별 다양화가 가장 중요한 것으로 나타났다. 이러한 연구결과는 정책 입안자와 실무자들에게 한류관광 활성화를 위한 정책적, 실무적 시사점을 제공할 것이다.
Intermediate endocrine-acinar pancreatic cells in duct ligation conditions (1997)

When tissues were subjected to 24 h of duct ligation, intermediate pancreatic cells simultaneously displaying endocrine and exocrine phenotypes appeared. Immunocytochemistry by laser scanning confocal microscopy revealed the appearance of a large number of these cells coexpressing insulin and amylase. These cells were located within the islets of Langerhans as well as in the acinar parenchyma. They were also detected in a culture system of isolated pancreatic cells. With the use of immunoelectron microscopy, two types of secretory granules were identified in these cells. One was insulin immunoreactive, whereas the other, resembling zymogen granules, contained amylase. Occasionally, some small granules displayed a double labeling for both secretory proteins. Numerous crinophagic bodies and autophagosomes containing insulin and/or amylase were also present. In situ hybridization, applied with the specific probes, confirmed the presence of both insulin and amylase mRNAs in these cells. Because duct ligation is known to induce insulin cell proliferation, the present results confirm that endocrine-acinar cells do appear in such condition and may represent intermediate steps in a transdifferentiating process.
Memory, attention, and executive function in chronic fatigue syndrome. (1996)

Patients with chronic fatigue syndrome have reduced attentional capacity resulting in impaired performance on effortful tasks requiring planned or self ordered generation of responses from memory.
Acute Renal Failure in Experimental Envenomation with Africanized Bee Venom (1998)

Human victims of multiple bee or wasp stings have been reported and develop severe clinical signs and symptoms. Acute renal failure (ARF), usually due to acute tubular necrosis (ATN) was a frequent complication. The pathogenetic mechanisms of ATN occurring in these accidents are still unclear. In the present study, female Wistar rats weighing 150-200 g were injected intravenously with Africanized bee venom at a dose of 0.4 microL/100 g body weight, and the kidney was observed under light and transmission electron microscopy and in immunohistochemical studies. The animals were divided into two groups: an Early group studied 3 to 8 hours after inoculation, and a Late group studied 24 to 30 hours after inoculation. The animals showed ATN mainly in the cortex and outer medulla with cast formation. After 24 hours, frequent mitotic figures were found in the tubular epithelium. Immunohistochemical studies revealed the presence of myoglobin and muscle actin in the tubular casts. Under electron microscopy, proximal tubule segments showed increasing intracytoplasmic vacuoles and attenuation of the brush border and of the basolateral infolding. This segment and the thick ascending limb of Henle's loop showed hydropic degeneration. Dead cells with apoptosis or necrosis due to cellular disintegration resulted in tubular basement membrane denudation. In the Late group, figures of intracytoplasmic myelin could be observed, some of them containing mitochondrial fragments. These changes are likely to be due to interactive effects of venom components, mainly mellitin and enzymes such as phospholipases, both acting on biological membranes. The ATN found was probably due to multiple causes, mainly a direct action of the venom on tubular cells, myoglobinuria, and perhaps ischemic mechanisms.
SCOUT: an approach to automating diagnoses of faults in large scale networks (2002)

There has been some success in automating the diagnosis of transmission problems in large telecommunications networks such as AT&T's digital communication network. This paper describes a new approach to automatic diagnosis that uses network topology and network behavior history to automate the troubleshooting of transmission problems in any large telecommunications network. We have developed and deployed a system based on this approach. This system is currently being used by technicians to troubleshoot problems in AT&T's network and it has been found to be very effective.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Multi-root I/O virtualization based redundant systems (2014)

Redundancy, a method being designed to prevent failures due to software/hardware problem, is one of the most common applications in fault-tolerance systems. In this paper, we provide a multi-root I/O virtualization (MR-IOV) based redundant system architecture which supports high performance, reliability, and scalability to improve conventional redundant architecture with hardware multiplexer for the fail-over function. In order to fix this drawback, we proposed a redundant architecture to save these statuses in the shared memory, and the backup system will apply the states to fail-over primary host. From experiment results, we observe that the proposed architecture is feasible and it is better than the conventional redundant architecture.
Thermomechanical frequency modulation of γ radiation (1991)

When a radio-frequency current is passed through a paramagnetic M\"ossbauer absorber containing $^{57}\mathrm{Fe}$, sidebands are generated on the 14.4-keV transition at ${\mathrm{\ensuremath{\omega}}}_{\ensuremath{\gamma}}$\ifmmode\pm\else\textpm\fi{}2n\ensuremath{\omega}, where n=1,2,..., and \ensuremath{\omega} is the applied frequency. The new aspect is that only sidebands of even orders appear. These sidebands are shown to be the result of thermomechanical oscillations induced by the rf current.
From approximate to optimal solutions: a case study of number partitioning (1995)

Given a set of numbers, the two-way partitioning problem is to divide them into two subsets, so that the sum of the numbers in each subset are as nearly equal as possible. The problem is NP-complete, and is contained in many scheduling applications. Based on a polynomial-time heuristic due to Karmarkar and Karp, we present a new algorithm, called Complete Karmarkar Karp (CKK), that optimally solves the general number-partitioning problem. CKK significantly outperforms the best previously-known algorithms for this problem. By restricting the numbers to twelve significant digits, we can optimally solve two-way partitioning problems of arbitrary size in practice. CKK first returns the Karmarkar-Karp solution, then continues to find better solutions as time allows. Almost five orders of magnitude improvement in solution quality is obtained within a minute of running time. Rather than building a single solution one element at a time, CKK constructs subsolutions, and combines them in all possible ways. CKK is directly applicable to the 0/1 knapsack problem, since it can be reduced to number partitioning. This general approach may also be applicable to other NP-hard problems as well. 1
Making things stick: enforcement and compliance (1998)

Environmental rules and regulations are only useful insofar as firms can be persuaded to comply with them-in full or in part. We survey the rapidly growing literature on the enforcement aspects of environmental policy. The difficulties facing any regulatory agency are likely to be exacerbated by information problems, penalty constraints, and the evasion efforts of firms, and we emphasize the role that recent innovative approaches to implementation can play in bolstering more traditional enforcement instruments.
The Nordic Aortic Valve Intervention (NOTION) trial comparing transcatheter versus surgical valve implantation: study protocol for a randomised controlled trial (2013)

ClinicalTrials.gov: NCT01057173.
On the impact of spatial parametric variations on MOS transistor mismatch (2002)

Quite often, especially during the development of advanced MOS fabrication processes, it is observed that for matched-pair MOS transistors with large device dimensions the general mismatch law "/spl sigma/(/spl Delta/P)=A/sub P///spl radic/(area)" (or its derivatives) does not always hold. This paper demonstrates that an explanation for this effect can be found in the presence of non-random parameter distributions over a wafer (referred to as spatial parametric variations). Furthermore, the use of a dedicated test structure to distinguish between random and non-random mismatch causes is presented.
A handoff authentication and key agreement scheme for integration of UMTS and 802.11 WLANs (2004)

We propose a secure handoff for integration of UMTS and IEEE 802.11 WLANs. The handoff between 802.11 WLAN and UMTS has some drawbacks and could be hijacked in the middle of a communication session. An architecture built for a secure handoff scheme is proposed to fix that problem. When UMTS users handover to an 802.11 WLAN environment, the dynamic key exchange protocol (DKEP) is used to build a secure handoff environment. The mobile station (MS) and the access point (AP) compute their session key individually. The protocol includes three phases, and all the steps of the phases are protected by public-key encryption. Therefore, no information can be hijacked between MS and AP. From the security analysis we know that the handoff between WLAN and UMTS is guaranteed in various aspects. For example, user identity and new register can be protected, avoiding denial of service, key reuse, and so on.
Quantitative structure-gas chromatographic retention relationship of polycyclic aromatic sulfur heterocycles using molecular electronegativity-distance vector (2011)

The chemical structures of 114 polycyclic aromatic sulfur heterocycles (PASHs) have been studied by molecular electronegativity-distance vector (MEDV). The linear relationships between gas chromatographic retention index and the MEDV have been established by a multiple linear regression (MLR) model. The results of variable selection by stepwise multiple regression (SMR) and the powerful predictive abilities of the optimization model appraised by leave-one-out cross-validation showed that the optimization model with the correlation coefficient (R) of 0.994 7 and the cross-validated correlation coefficient (Rcv) of 0.994 0 possessed the best statistical quality. Furthermore, when the 114 PASHs compounds were divided into calibration and test sets in the ratio of 2:1, the statistical analysis showed our models possesses almost equal statistical quality, the very similar regression coefficients and the good robustness. The quantitative structure-retention relationship (QSRR) model established may provide a convenient and powerful method for predicting the gas chromatographic retention of PASHs.
Waste Generation and Minimization in Semiconductor Industry (1994)

Semiconductors are electrical devices that perform functions such as processing and display, power handling, and conversion between light and electrical energy. Semiconductor production processes involve over 100 proprietary solutions and 200 generic materials to achieve the final product. This industry generates significant quantities of spent solvents and liquids containing metals. The economic and liability incentives caused by increasing disposal costs and more stringent regulations are resulting in efforts to minimize such wastes at the source. This paper provides information about: (1) The type and quantity of wastes produced by this industry, much of which are listed hazardous wastes; (2) the hazardous waste disposal problems facing this industry; and (3) waste minimization case studies.
Inhibition of gelatinase A (MMP-2) by batimastat and captopril reduces tumor growth and lung metastases in mice bearing Lewis lung carcinoma (1999)

We have examined the effects of the synthetic matrix metalloproteinase inhibitor, batimastat (BB-94) and the angiotensin-converting enzyme inhibitor, captopril, on metalloproteinase activity of murine Lewis-lung-carcinoma cells (3LL) in vitro, and on local growth and lung metastasis of the same tumor implanted intramuscularly in syngeneic C57BL/6 mice. The effect of BB-94 and captopril on the survival of the 3LL-tumor-bearing mice was also examined. Here we report that captopril treatment resulted in decreased transcription and protein levels of gelatinase A by 3LL cells. Both BB-94 and captopril also prevented substrate degradation by gelatinase A and B released in conditioned medium by cultured cells. Treatment of tumor-bearing animals with BB-94 (i.p.) or captopril (in drinking water) resulted in significant inhibition of the mean tumor volume (25 and 33% respectively) and of the mean lung metastasis number (26 and 29% respectively). When both agents were given, they acted in synergy, resulting in 51 and 80% inhibition of tumor growth and metastasis. The survival time of the mice treated with both BB-94 and captopril was also significantly longer compared with the groups treated with each agent alone or with the vehicle. Our data support the hypothesis of an essential role of metalloproteinase(s) in the metastatic process. Moreover, blockade of invasion, angiogenesis and other processes mediated by metalloproteinases may underlie the anti-tumor and anti-metastatic effect of BB-94 and captopril and their combination. It is conceivable that this combination could be tested in selected clinical conditions as an adjuvant modality to cytotoxic therapy.
Viral DNA Synthesis Defects in Assembly-Competent Rous Sarcoma Virus CA Mutants (2001)

The major structural protein of the retroviral core (CA) contains a conserved sequence motif shared with the CA-like proteins of distantly related transposable elements. The function of this major region of homology (MHR) has not been defined, in part due to the baffling array of phenotypes in mutants of several viruses and the yeast TY3. This report describes new mutations in the CA protein of Rous sarcoma virus (RSV) that were designed to test whether these different phenotypes might indicate distinct functional subdomains in the MHR. A comparison of 25 substitutions at 10 positions in the RSV conserved motif argues against this possibility. Most of the replacements destroyed virus infectivity, although either of two lethal phenotypes was obtained depending on the residue introduced. At most of the positions, one or more replacements (generally the more conservative substitutions) caused a severe replication defect without having any obvious effects on virus assembly, budding, Gag-Pol and genome incorporation, or protein processing. The mutant particles exhibited a defect in endogenous viral DNA synthesis and showed increased sensitivity of the core proteins to detergent, indicating that the mutations interfere with the formation and/or activity of the virion core. The distribution of these mutations across the MHR, with no evidence of clustering, suggests that the entire region is important for a critical postbudding function. In contrast, a second class of lethal substitutions (those that destroyed virus assembly and release) consists of alterations that are expected to cause severe effects on protein structure by disruption either of the hydrophobic core of the CA carboxyl-terminal domain or of the hydrogen bond network that stabilizes the domain. We suggest that this duality of phenotypes is consistent with a role for the MHR in the maturation process that links the two parts of the life cycle.
Designing and analyzing the structure of Tat-BoNT/A(1-448) fusion protein: An <i>in silico</i> approach. (2014)

<i>Clostridium botulinum</i> type A (BoNT/A) produces a neurotoxin recently found to be useful as an injectable drug for the treatment of abnormal muscle contractions. The catalytic domain of this toxin which is responsible for the main toxin activity is a zinc metalloprotease that inhibits the release of neurotransmitter mediators in neuromuscular junctions. A cell penetrating cationic peptide, Tat, which is a truncated N-terminal part of the Tat protein from human immunodeficiency virus, can help the toxin penetrate the skin uninvasively. This study aimed at an <i>in silico</i> analyses of the Tat-BoNT/A(1-448) fusion protein structure. A genomic construct was designed and optimized based on <i>E. coli</i> codon usage. The structure of mRNA as well as the properties of hypothetical chimeric protein was then analyzed by bioinformatic tools. Afterwards, the secondary and tertiary structures of the fusion protein were predicted by GOR4 and I-TASSER online web servers. The interaction with synaptosomal associated protein 25kDa (SNAP-25) was also analyzed as a natural substrate for the toxin. Based on the studied secondary and tertiary structures of the protein, the selected order of fusion proteins provides the natural activity of each peptide. Energy calculating data show that the acquired thermodynamic ensemble related to the mRNA structure was-1473.2 kJ/mol (-352.10 kcal/mol) and both total protein energy (Etotal) and shape related energy(Eshape) were calculated as -2294.2kJ/mol (-548.32 kcal/mol). The stability index of TAT-BoNT/A was computed to be 27.22 which has an acceptable stability as compared to that of native BoNT/A (22.39).
Exercise-induced proteinuria in well-trained athletes (1990)

We studied the rate of urinary excretion of albumin, alpha 1-microglobulin (as an indicator of the renal tubular involvement), sodium, potassium, and creatinine in the basal state (overnight urine collection) and after physical exercise (training session) in 10 professional cyclists, to verify whether protein excretion is increased even in well-trained athletes after physical effort. In addition, we wanted to understand whether the origin of exercise-induced proteinuria was glomerular, tubular, or both. Compared with the basal state (overnight collection), exercise significantly (P less than 0.01) increased the excretion rate of albumin (4.2 +/- 2.6 micrograms/min vs 18.1 +/- 10.6 micrograms/min, mean +/- SD), Na, and K, and also the urinary volume. Creatinine output was not affected by exercise. The mean (+/- SD) overnight excretion rate of albumin by athletes was quite similar to that found for 91 healthy nonathletes at rest (4.6 +/- 2.7 micrograms/min). The mean exercise-related excretion of alpha 1-microglobulin by the athletes significantly exceeded the overnight value (6.6 vs 0.3 mg/L, P = 0.037). Our study indicates that (a) albuminuria furnishes the greater contribution to the increase in exercise-induced proteinuria; (b) the exercise proteinuria is both glomerular and tubular in origin, and is reversible; (c) the enhanced protein requirement of athletes may in part be due to the recurrent excretion of proteins in the urine after physical effort.
Scanning MEMS Mirror for High Definition and High Frame Rate Lissajous Patterns (2019)

Scanning MEMS (micro-electro-mechanical system) mirrors are attractive given their potential use in a diverse array of laser scanning display and imaging applications. Here we report on an electrostatic MEMS mirror for high definition and high frame rate (HDHF) Lissajous scanning. The MEMS mirror comprised a low Q-factor inner mirror and frame mirror, which provided two-dimensional scanning at two similar resonant scanning frequencies with high mechanical stability. The low Q inner mirror enabled a broad frequency selection range. The high definition and high frame rate (HDHF) Lissajous scanning of the MEMS mirror was achieved by selecting a set of scanning frequencies near its resonance with a high greatest common divisor (GCD) and a high total lobe number. The MEMS mirror had resonant scanning frequencies at 5402 Hz and 6702 Hz in <i>x</i> and <i>y</i> directions, respectively. The selected pseudo-resonant frequencies of 5450 Hz and 6700 Hz for HDHF scanning provided 50 frames per second with 94% fill factor in 256 × 256 pixels. This Lissajous MEMS mirror could be utilized for assorted HDHF laser scanning imaging and display applications.
Interconnected logistic networks and protocols: simulation-based efficiency assessment (2013)

Logistic networks intensely use means of transportation and storage facilities to deliver goods. However, these logistic networks are still poorly interconnected and this fragmentation is responsible for a lack of consolidation and thus efficiency. To cope with the seeming contradiction of just-in-time deliveries and challenging emissions targets, a major improvement in supply networks is sought here. This new organisation is based on the universal interconnection of logistics services, namely a Physical Internet where goods travel in modular containers for the sake of interconnection in open networks. If from a logical point of view, merging container flows should improve efficiency, no demonstration of its potential has been carried out prior to the here reported research. To reach this potentiality assessment goal, we model the asynchronous shipment and creation of containers within an interconnected network of services, find the best path routing for each container and minimise the use of transportations means. To carry out the demonstration and assess the associated stakes, we use a set of actual flows from the fast-moving consumer goods sector in France. Various transportation protocols and scenarios are tested, revealing encouraging results for efficiency indicators such as CO2 emissions, cost, lead time, delivery travel time, and so forth. As this is a first work in the field of flows transportation, the simulation model and experiment exposes many further research avenues.
Protocol and signalling aspects of joint detection CDMA (2002)

In the early 1990s investigations towards an air interface for UMTS and IMT2000 were started at the Research Group for RF Communications. The result is an air interface, which uses a combination of the multiple access schemes FDMA, TDMA and CDMA, and in which signal separation in the receiver is performed by joint detection (JD). The air interface is termed JD-CDMA and adopts the philosophy of the de facto world standard GSM to an extent as large as possible. The authors investigate which extensions of the existing GSM protocols are necessary to support JD-CDMA, and how JD-CDMA protocols can be implemented.