gebhart/patrepeval huggingface dataset:
Experiments on a Real-Time Energy Management System for Islanded Prosumer Microgrids (2019)

This paper presents an experimental demonstration of a novel real-time Energy Management System (EMS) for inverter-based microgrids to achieve optimal economic operation using a simple dynamic algorithm without offline optimization process requirements. The dynamic algorithm solves the economic dispatch problem offering an adequate stability performance and an optimal power reference tracking under sudden load and generation changes. Convergence, optimality and frequency regulation properties of the real-time EMS are shown, and the effectiveness and compatibility with inner and primary controllers are validated in experiments, showing better performance on optimal power tracking and frequency regulation than conventional droop control power sharing techniques.
Recoverable degradation of blue InGaN-based light emitting diodes submitted to 3 MeV proton irradiation (2014)

This paper reports on the degradation and recovery of two different series of commercially available InGaN-based blue light emitting diodes submitted to proton irradiation at 3 MeV and various fluences (1011, 1013, and 1014 p+/cm2). After irradiation, we detected (i) an increase in the series resistance, in the sub-turn-on current and in the ideality factor, (ii) a spatially uniform drop of the output optical power, proportional to fluence, and (iii) a reduction of the capacitance of the devices. These results suggest that irradiation induced the generation of non-radiative recombination centers near the active region. This hypothesis is further confirmed by the results of the recovery tests carried out at low temperature (150 °C).
Liquid‐crystal alignment on rubbed polyimide films with various side chains (2000)

Abstract— A series of polyimides containing various side chains was synthesized in order to investigate the effect of side chains on the alignment of liquid crystals on the rubbed surface. Here, the side chains include short flexible alkyl spacers and isomeric biphenyl mesogens. The pretilting of liquid‐crystal (LC) molecules was found to be very sensitive to the isomeric structure of biphenyl mesogen end groups as well as the conformation and length of flexible spacers, in addition to the rubbing process. The pretilt angle of LC molecules in the LC cell was achieved in a wide angle range of 8–27°, depending upon the rubbing density as well as the side chains. The high performance in the pretilt and alignment of LCs might be attributed mainly to a strong interaction between the biphenyl mesogen end group in the side chain and the LC molecule in addition to the microgrooves generated in the rubbing direction.
Abstract B35: High-throughput cell line profiling for identification of anticancer drug sensitivity and resistance biomarkers with OncoPredictor (2010)

Abstract Tumor derived cell lines have been in use for cancer drug profiling as evidenced by the establishment of NCI-60 panel as a drug discovery tool in early 1990s. In recent years, due to the advancement of targeted therapies in cancer, screening of larger cell panels with greater genetic heterogeneity has become very important not only to measure efficacy of the compounds but also for identifying the biomarkers that are responsible for the efficacy. Here we present data from OncoPredictorSM, a cellular screening and bioinformatics platform able to (1) evaluate multiple types of genomic biomarkers for association with in vitro drug response and (2) analyze identified biomarkers in clinical tumor populations, thereby suggesting potential drug development strategies. The cellular screening component, OncoPanel™, is comprised of a large panel of human tumor-derived cell lines from different origins with broad genetic heterogeneity providing a sensitive method of comparing proliferation or cytotoxicity (resistance or sensitivity) across genotypes. Our cell line panel consists of 240 cell lines that span a wide variety tumor tissue types including lung, breast, stomach, colon, ovary, liver, skin, kidney, bladder, prostate, pancreas, head and neck, brain, hematopoetic, and lymphoid tumors. We have mRNA expression, SNP and mutation data to characterize these cell lines. The media and culture conditions are standardized and optimized so that the genetic heterogeneity of the cell line will be responsible for the phenotypic responses obtained. We generate simultaneous data for each compound at 10 concentrations (in triplicates) resulting in precise IC50/EC50 values for analysis and comparison. Results from a case study will be presented to depict the very robust data quality including the doubling time for the cell lines. Also, sensitive and resistance data with 11 known anticancer agents including inhibitors of mTorr, ABL, MEK, PDGF, VEGF, FLT3, Aurora kinases, HSP90, EGFR, Topo II, and microtubulin disassembly will be presented using the robust high content data from these cell lines. As expected, the most sensitive cell lines against a clinical ABL inhibitor were the CML-derived cell lines. On the other hand, many of the colon, melanoma and pancreatic cell lines were sensitive to MEK inhibitor. Sensitive and resistant cells were further profiled against, mutation, expression, and SNP data to identify genes involved in the sensitive/resistant phenotypes using sophisticated bioinformatic analysis tools to identify genomic biomarker profiles and to estimate their frequency in clinical populations (data presented separately). OncoPredictor is ideally suited for prioritization of the leads, positioning of the leads against cancer types, repositioning of clinical candidates or drugs for supplemental indication, combination therapies, and for biomarker identification and characterization in clinical populations. Citation Information: Clin Cancer Res 2010;16(14 Suppl):B35.
High Resolution Mapping of the B Cell Epitopes of Staphylokinase in Humans Using Negative Selection of a Phage-Displayed Antigen Library (1998)

Staphylokinase (Sak), a 16-kDa protein secreted by Staphylococcus aureus, induces fibrin-specific thrombolysis in patients with thrombotic disorders. However, Sak also elicits high titers of neutralizing Abs that persist for several months and preclude its repeated use in humans. To identify the antigenic determinants of Sak recognized by humans, a phage-displayed library of Sak variants was selected for mutants that escape binding to an affinity matrix derivatized with patient-specific polyclonal anti-Sak Abs. Fifty-six escape Sak variants were identified after three selection cycles using human polyclonal anti-Sak IgGs obtained from four different patients. DNA sequencing revealed 213 amino acid substitutions, of which 73% were found at 25 positions clustered in eight discontinuous Sak antigenic segments. Although each antigenic segment was recognized to a variable extent by each patient antiserum, the main epitopes of Sak in all patients were roughly targeted to two large discontinuous areas covering 35% of the solvent-accessible surface of Sak. The antigenic area I comprises three segments centered on residues 66, 73, and 135, while the antigenic area II consists of four segments centered on positions 20, 95, 102, and 121. These results suggest that a secondary immune response against Sak can occur in patients, and confirm an initial site-directed mutagenesis study wherein amino acid Lys74 was shown to play a prominent antigenic role. Comprehensive mapping of the most relevant sites of Sak that are antigenic for humans will guide efforts to modulate the immunogenicity of this therapeutically important molecule.
Accidental Torsion in Buildings: Analysis versus Earthquake Motions (2001)

A simplified analysis procedure has been developed to consider accidental torsion in building design that is rational and convenient relative to building codes. This procedure is extended and evaluated in this paper against measured accidental torsion determined from motions of 12 buildings—with nominally-symmetric plan—recorded during Northridge (1994), Loma Prieta (1989), Whittier (1987), and Upland (1990) earthquakes. The selected buildings include structures in reinforced concrete and in steel that cover a wide range of structural systems, including moment resisting frames, shear walls, braced frames, and hybrid systems. After the measured torsion is interpreted and compared to analytical estimates, it is demonstrated that this procedure is sufficiently accurate to be used in design applications.
The Distribution of Asymmetric and Symmetric Chains in Highly Isotactic Polypropylenes (1999)

Structural distributions have been determined for the components of an impact copolymer, which are prepared in series reactors with the same magnesium chloride supported titanium based Ziegler Natta catalyst system. The structural distribution of a polypropylene homopolymer prepared in the first reactor is compared to the structural distribution of a downstream E/P copolymer to ascertain if this information is revealing about the catalyst site distribution. The amorphous and crystalline components of the second stage E/P copolymer exhibit completely different E/P triad sequence distributions, which suggest they originate from different types of catalyst sites. The homopolymer asymmetric/symmetric chain structural distribution obtained from a Doi two state statistical fit of the pentad/heptad meso,racemic sequence distributions is compared to the ratio of crystalline to amorphous E/P copolymers prepared in the second stage. A distribution of 80/20 for asymmetric versus symmetric chains satisfactorily fits the Doi two state homopolymer statistical model and accounts for the structural distributions observed for the E/P copolymer ICP components.
Synthesis of surfactants from 1‐olefins wo bromoalkoxylation reaction (1991)

Alkyl β‐bromoalkyl ether derivatives (I) (isomeric mixture) were prepared by the bromoalkoxylation reaction of olefins with N ‐bromosuccinimide (NBS) and appropriate alcohols. A series of nonionic surfactants was obtained by the reaction of I with glycols or ethanolamines. The distribution of two isomers (Markovnikov‐type and anti‐Markovnikov‐type) in products was found to be slightly different from that in the starting material (I). Surface properties of several nonionic surfactants, which were prepared from I, were presented and discussed based on the difference in the structures.
Cased-Hole Cleaning: Do Annular Velocity, Annular Coverage and Contact Time Equal Mud Removal? (2007)

Abstract Mud-to-brine displacement efficiency can be difficult to quantify. Metrics to determine the success or failure of the displacement operation have traditionally been based upon the clarity of the completion brine that follows the spacers, the interface volumes of mud and completion brine, a visual determination of the cleanliness of the drillpipe pulled from the hole, and the time and materials required to filter the fluid. Despite their widespread use, however, these factors may not adequately characterize the quality of displacements in critical wells. Opportunities for improvement are largely affected by how well the displacement process can be understood. This can be difficult with the few direct and indirect parameters used to evaluate mud-to-brine displacement quality. The authors initiated a study of samples captured during displacement circulations to examine the effects of spacer properties, volumes, pump rate, and chemical concentration on mud removal. The laboratory analyses inspected return samples of mud, spacers, and displacing fluids from 27 cased-hole wellbore displacements of oil-based and synthetic-based drilling mud in the Gulf of Mexico. Results from this study suggest that criteria such as annular coverage, contact time, and annular velocity of the wash spacer(s), which have become the basis for most displacement programs, although critical to overall efficiency, are not the primary agents of mud removal during a wellbore cleanup. Data correlations between the volume of mud observed in the samples analyzed and certain spacer characteristics suggest that cased-hole cleaning, when defined as mud removal, is a function of the size of a viscous spacer relative to hole size. This observation should simplify the displacement design process.
Kinetics of Methylation and Ethylation of Benzene and Toluene in 1,2,4-Trichlorobenzene under the Influence of Aluminum Bromide; Mechanism of the Alkylation Reaction<sup>1,2</sup> (1956)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTKinetics of Methylation and Ethylation of Benzene and Toluene in 1,2,4-Trichlorobenzene under the Influence of Aluminum Bromide; Mechanism of the Alkylation Reaction1,2Hans Jungk, Charles R. Smoot, and Herbert C. BrownCite this: J. Am. Chem. Soc. 1956, 78, 10, 2185–2190Publication Date (Print):May 1, 1956Publication History Published online1 May 2002Published inissue 1 May 1956https://pubs.acs.org/doi/10.1021/ja01591a045https://doi.org/10.1021/ja01591a045research-articleACS PublicationsRequest reuse permissionsArticle Views174Altmetric-Citations22LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Broadband Substrate Integrated Waveguide 4$\,\times\,$4 Nolen Matrix Based on Coupler Delay Compensation (2011)

A broadband Nolen matrix in substrate integrated waveguide (SIW) technology is proposed and studied in this paper. Being serial feeding networks, Nolen matrices usually introduce significant phase dispersion in their standard form, thus limiting effective bandwidth. In this work, broadband frequency operation is achieved with adequate coupler delay compensation, resulting in a more "parallel" matrix topology. Consequently, H-plane couplers with continuous aperture are preferred in the proposed design as opposed to the cross-couplers previously used in the "serial" configuration. The SIW couplers and phase shifters of a balanced amplitude 4×4 Nolen matrix are designed at 77 GHz for radar applications. The resulting matrix that combines these elementary building blocks is fabricated and measured, and measured characteristics are in good agreement with theoretical and simulated predictions. This first design achieves excellent results over a 11.7% frequency bandwidth centered at 77 GHz. This modified Nolen matrix combines advantages of standard Nolen and Butler matrices and may be used as a building block for generalized orthogonal matrices.
Magnetic Nanobeads Decorated with Silver Nanoparticles as Cytotoxic Agents and Photothermal Probes (2012)

A versatile method for decorating magnetic nanobeads (being composite materials from polymers and superparamagnetic nanoparticles) with silver nanoparticles of 3-6 nm size is presented. Control over the silver nanoparticle coverage at the nanobead surface is achieved by changing the reaction parameters. Moreover, the silver-decorated magnetic nanobeads (Ag-MNBs) are studied with respect to their in vitro cytotoxicity on two distinct tumour cell lineages under different parameters, i.e., dose, incubation time, magnetic field applied during the culturing, silver ion leakage, and colloidal stability. It is found that enhanced magnetically mediated cellular uptake and silver ion leakage from the Ag-MNBs surface are the main factors which affect the toxicity of the Ag-MNBs and allow the half-maximal inhibitory dose of silver to be reduced to only 32 μg mL(-1) . Furthermore, a synergic cytotoxicity induced by photo-activation of silver nanoparticles was also found.
Multiple Forms of the SH2-Containing Inositol Phosphatase, SHIP, Are Generated by C-Terminal Truncation (1998)

The SH2-containing inositol phosphatase, SHIP, often appears as multiple bands in anti-SHIP immunoblots. To characterize these bands, antisera were generated against the N-terminal (anti-N), mid-region (anti-M), and C-terminal (anti-C) portions of SHIP. Immunoprecipitation and immunoblotting studies showed that 145-, 135-, 125-, and 110-kD bands were detected in lysates from the murine hematopoietic cell line, DA-ER, with either anti-N or anti-M antisera, whereas only the 145- and 135-kD bands were recognized by the anti-C antiserum. This finding suggested that the smaller proteins might be C-terminal truncations of the full-length SHIP. To confirm this and determine if these proteins arose through alternate splicing or posttranslational cleavage, a 5′-hemagglutin (HA)-tagged full-length SHIP cDNA was expressed in these cells. We observed, via Western analysis with anti-HA antibodies, the same 4 bands with either anti-N or anti-M and only the 145- and 135-kD bands with anti-C immunoprecipitation. After interleukin-3 stimulation of HA-SHIP–expressing DA-ER cells, only the 145-kD form coprecipitated with Shc, raising the possibility that different forms of SHIP may have distinct intracellular sites. This was confirmed by subcellular fractionation, which showed that only the 110-kD form is present in the cytoskeleton of DA-ER cells. This 110-kD form possesses the same PIP3 5-ptase activity as the 145-kD form and can be generated from the latter in vitro by digestion with calpain. It is therefore possible that the different forms of SHIP are generated in vivo by calpain-mediated C-terminal truncations and perform distinct functions within hematopoietic cells. © 1998 by The American Society of Hematology.
Reconfigurable Printed Liquids (2018)

Liquids lack the spatial order required for advanced functionality. Interfacial assemblies of colloids, however, can be used to shape liquids into complex, 3D objects, simultaneously forming 2D layers with novel magnetic, plasmonic, or structural properties. Fully exploiting all-liquid systems that are structured by their interfaces would create a new class of biomimetic, reconfigurable, and responsive materials. Here, printed constructs of water in oil are presented. Both form and function are given to the system by the assembly and jamming of nanoparticle surfactants, formed from the interfacial interaction of nanoparticles and amphiphilic polymers that bear complementary functional groups. These yield dissipative constructs that exhibit a compartmentalized response to chemical cues. Potential applications include biphasic reaction vessels, liquid electronics, novel media for the encapsulation of cells and active matter, and dynamic constructs that both alter, and are altered by, their external environment.
Theory of Neutral-Ionic Transition in Organic Crystals. IV. Phenomenological Viewpoint (1986)

The phenomenological theory of the neutral-ionic transition in TTF-Chloranil is developed taking into account the thermal excitations of the domain walls on a chain and the three dimensional interchain interactions. The changes in various physical quantities around the transition point reflect the competition between these two effects. We mainly discuss the optical spectra which give the microscopic probes of the degree of charge transfer ρ at each molecule. The effect of a single impurity detected in the optical spectra is also discussed. Comparing with the experimental data in TTF-Chloranil, the following two conclusions are derived for this material. (1) The energy of the domain wall is small (of the order of room temperature). (2) The interchain interaction is weak effectively.
Ergodic theory of stochastic decision free Petri nets (2003)

The class of decision-free Petri nets under stochastic timing assumptions, also known as stochastic event graphs, is considered. Under the assumption that the variables used for the timing of an event graph form stationary and ergodic sequences of random variables, use is made of an associated stochastic recursive equation in order to construct the event graph's stationary and ergodic regime. In particular, the conditions under which the existence of this regime is guaranteed are determined.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Propranolol Diminishes Extremity Blood Flow in Burned Patients (1991)

Beta adrenergic blockade diminishes the catecholamine-mediated elevations in heart rate and myocardial contractility that characterize postburn hypermetabolism. To examine how these alterations in cardiac performance affect peripheral perfusion, indirect calorimetry and leg blood flow were measured before and then after a 2-hour intravenous propranolol infusion. Five severely burned patients (55% + 7% total burn surface area), given propranolol at 8 micrograms/kg/minute, had a significant reduction in cardiac index and heart rate with an increased leg vascular resistance resulting in a decrease in extremity perfusion. Four healthy volunteers were given propranolol at 5 micrograms/kg/minute, resulting in a comparable decrease in heart rate, yet there was no change in leg vascular resistance or extremity perfusion. In both patient groups, propranolol decreased the plasma lactate concentration. This suggests that in hypermetabolic patients, beta adrenergic blockade reduces peripheral perfusion and that peripheral perfusion is not a principal determinate of plasma lactate levels. Rather adrenergic blockade appears to decrease lactate concentration as a consequence of the inhibition of lipolysis.
Coarse-grained potential models for structural prediction of carbon dioxide (CO2) in confined environments (2012)

In this paper, we propose coarse-grained single-site (CGSS), wall-CO(2), and CO(2)-CO(2) interaction potential models to study the structure of carbon dioxide under confinement. The CGSS potentials are used in an empirical potential based quasi-continuum theory, EQT, to compute the center-of-mass density and potential profiles of CO(2) confined inside different size graphite slit pores. Results obtained from EQT are compared with those obtained from all-atom molecular dynamics (AA-MD) simulations, and are found to be in good agreement with each other. Though these CGSS interaction potentials are primarily developed and parameterized for EQT, they are also used to perform coarse-grained molecular dynamics (CG-MD) simulations. The results obtained from CG-MD simulations are also found to be in reasonable agreement with AA-MD simulation results.
Respiratory Diseases (2009)

Upper respiratory tract infections are the most common type of infectious diseases and a leading cause of outpatient illness (1,2).
March consultation #6 (2012)

Journal of Cataract & Refractive Surgery: March 2012 - Volume 38 - Issue 3 - p 558-559 doi: 10.1016/j.jcrs.2012.01.007