gebhart/patrepeval huggingface dataset:
Antigenic relatedness between arenaviruses defined at the epitope level by monoclonal antibodies (1991)

Monoclonal antibodies (MAbs) were produced against two African arenaviruses, Lassa virus and Mopeia virus. Competitive binding analysis of MAbs identified four antigenic sites on the nucleoprotein (NP), two on glycoprotein 1 (GP1) and six on glycoprotein 2 (GP2) of the Josiah strain of Lassa virus. 64 virus isolates from western, central and southern Africa were all consistently distinguishable by MAbs to certain epitopic sites on GP1, GP2 and NP viral proteins. Furthermore, MAbs to Lassa virus GP1 and NP uniformly distinguished viruses from the West African countries of Sierra Leone, Liberia and Guinea from those of Nigeria. GP2-directed MAbs to two African arenaviruses reacted broadly with South American arenaviruses demonstrating that an epitopic site on GP2 may be the most highly conserved antigen in the arenavirus group.
In Situ, Time-Resolved, and Mechanistic Studies of Metal–Organic Framework Nucleation and Growth (2018)

The vast chemical and structural diversity of metal-organic frameworks (MOFs) opens up the exciting possibility of "crystal engineering" MOFs tailored for particular catalytic or separation applications. Yet the process of reaction discovery, optimization, and scale-up of MOF synthesis remains extremely challenging, presenting significant obstacles to the synthetic realization of many otherwise promising MOF structures. Recently, significant new insights into the fundamental processes governing MOF nucleation and growth, as well as the relationship between reaction parameters and synthetic outcome, have been derived using powerful in situ, time-resolved and/or mechanistic studies of MOF crystallization. This Review provides a summary and associated critical analysis of the results of these and other related "direct" studies of MOF nucleation and growth, with a particular emphasis on the recent advances in instrument technologies that have enabled such studies and on the major hypotheses, theories, and models that have been used to explain MOF formation. We conclude with a summary of the major insights that have been gained from the work summarized in this Review, outlining our own perspective on potential fruitful new directions for investigation.
TANGRAM: development of object-oriented frameworks for TINA-C-based multimedia telecommunication applications (2002)

Presents some results of the TANGRAM project, which prototypes and evaluates an environment supporting the object-oriented development of distributed multimedia applications based on the architectures developed by the "Telecommunications Information Networking Architecture Consortium" (TINA-C). These architectures suggest how to structure software for information networking. Their strength is the applicability for a wide range of telecommunication services and the independence of system and network technology. To enforce the approach taken in TINA-C, the concepts of abstract object-oriented frameworks are introduced and applied. Such frameworks can be a means to support the design and development of software sharing the advantages of object-orientation like reusability, scalability and customizability.
A Behavioral Approach to the Treatment of Stuttering (1968)

A behavioral analysis of the disorder of stuttering is presented. The author outlines a program of treatment for severe adult stutterers which is based partly on this behavioral analysis and partly on empirical observations about means of influencing the frequency and severity of stuttering. The treatment involves the use of a miniaturized electronic metronome which is worn behind the ear like the hearing aid it resembles.
Mode of action of a new Aspergillus oryzae carboxypeptidase O-1. (1981)

The serine carboxypeptidases (EC. 3.4. 16. 1) release most carboxyterminal amino acids from peptides and proteins. However, the rate of hydrolysis by acid carboxypeptidases from Aspergillus saitoi1 ~3) and Penicillium janthinel-
Photoenzymatic repair of ultraviolet damage in DNA. II. Formation of an enzyme-substrate complex. (1962)

The photoenzyme from bakers' yeast which repairs ultraviolet-inactivated transforming DNA is mechanically bound to ultraviolet-irradiated DNA in the dark, but not to unirradiated DNA. In the bound condition it is stabilized against inactivation by heat and heavy metals. Both the mechanical binding and stabilization are eliminated by illumination. These observations are consistent with the reaction scheme suggested by kinetic studies, in which the enzyme combines with the ultraviolet lesions in DNA and the complex absorbs light, producing repair and subsequent liberation of the enzyme. The approximately exponential decrease of heat stabilization during illumination gives the first order rate constant for the light-dependent step at the corresponding light intensity. This quantity in turn sets limits on the possible magnitude of the molar absorption coefficient of the enzyme-substrate complex and on the quantum yield of the process.
Up-regulation of uPARAP/Endo180 during culture activation of rat hepatic stellate cells and its presence in hepatic stellate cell lines from different species (2009)

These results demonstrate that uPARAP/Endo180 expression by rat HSCs is strongly up-regulated during culture activation and identify this receptor as a feature common to culture-activated HSCs.
A 5.8-Gb/s Adaptive Integrating Duobinary DFE Receiver for Multi-Drop Memory Interface (2017)

This paper describes a 5.8 Gb/s adaptive integrating duobinary decision-feedback equalizer (DFE) for use in next-generation multi-drop memory interface. The proposed receiver combines traditional interface techniques like the integrated signaling and the duobinary signaling, in which the duobinary signal is generated by current integration in the receiver. It can address issues such as input data dependence during integration, need for precursor equalization, high equalizer gain boosting, and sensitivity to high-frequency noise. The proposed receiver also alleviates DFE critical timing to provide gain in speed, and embed DFE taps in duobinary decoding to provide gain in power and area. The adaptation for adjusting the equalizer common-mode level, duobinary zero level, tap coefficient values, and timing recovery is incorporated. The proposed DFE receiver was fabricated in a 45 nm CMOS process, whose measurement results indicated that it worked at 5.8 Gb/s speed in a four-drop channel configuration with seven slave ICs, and the bathtub curve shows 36% open for 10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">-10</sup> bit error rate.
Serial updating rule for blind separation derived from the method of scoring (1999)

In the context of blind source separation, the method of scoring based on the inverse of the Fisher information matrix (FIM) becomes the serial updating learning rule with an equivariant property. This learning rule can be simplified to a low-complexity algorithm by using the asymptotic form of the FTM around the equilibrium. The simplified learning rule is still general enough to include some existing equivariant blind separation algorithms as its special cases.
A Versatile Nanotheranostic Agent for Efficient Dual‐Mode Imaging Guided Synergistic Chemo‐Thermal Tumor Therapy (2015)

The integration of efficient imaging for diagnosis and synergistic tumor therapy into a single‐component nanoplatform is much promising for high efficacy tumor treatment but still in a great challenge. Herein, a smart and versatile nanotheranostic platform based on hollow mesoporous Prussian blue nanoparticles (HMPBs) with perfluoropentane (PFP) and doxorubicin (DOX) inside, has been designed, for the first time, to achieve the distinct in vivo synergistic chemo‐thermal tumor therapy and synchronous diagnosis and monitoring by ultrasound (US)/photoacoustic (PA) dual mode imaging. The prepared HMPBs show excellent photothermal conversion properties with large molar extinction coefficient (≈1.2 × 10 11 m −1 cm −1 ) and extremely high photothermal conversion efficiency (41.4%). Such a novel theranostic nanoplatform is expected to overcome the inevitable tumor recurrence and metastasis resulting from the inhomogeneous ablation of single thermal therapy, which will find a promising prospect in the application of noninvasive cancer therapy.
Diagnostic Yield of a Positive Fecal Occult Blood Test Found on Digital Rectal Examination (1991)

The value of a positive fecal occult blood test (FOBT) found at the time of digital rectal examination is disputed. To determine the significance of a positive FOBT obtained in this manner, the records of 270 patients who underwent colonoscopy for any positive FOBT were retrospectively reviewed. Occult blood was found in 144 patients at the time of digital rectal examination and in 126 individuals after they submitted three spontaneously passed stool specimens. Of the patients with a positive FOBT on rectal examination, 77% were hospitalized at the time compared with only 17% of those with positive FOBTs from spontaneously passed stools. The frequency of colonic abnormalities was similar with both stool collection methods in inpatients and outpatients. No statistically significant differences in neoplastic polyp or colon cancer detection rates, nor in the finding of hemorrhoids or other anorectal abnormalities, were apparent. Therefore, the belief that a positive FOBT found at the time of digital examination can or should be discounted as a false positive (because of the presence of hemorrhoids or other lesions prone to trauma at the time of digital examination) was not substantiated by this study.
I REUNION SOBRE ADMINISTRACION DEL INTERCAMBIO ACADEMICO INTERNACIONAL (1986)

LA DIRECCION GENERAL DE INTERCAMBIO ACADEMICO (DGIA) CONVOCO A DESTACADOS UNIVESITARIOS Y REPRESENTANTES DE MISIONES DIPLOMATICAS ACREDITADAS EN MEXICO A LA I REUNION SOBRE ADMINISTRACION DEL INTERCAMBIO ACADEMICO INTERNACIONAL.
Partial Fingerprint Matching through Region-Based Similarity (2014)

Despite advances in fingerprint matching, partial/incomplete/fragmentary fingerprint recognition remains a challenging task. While miniaturization of fingerprint scanners limits the capture of only part of the fingerprint, there is also special interest in processing latent fingerprints which are likely to be partial and of low quality. Partial fingerprints do not include all the structures available in a full fingerprint, hence a suitable matching technique which is independent of specific fingerprint features is required. Common fingerprint recognition methods are based on fingerprint minutiae which do not perform well when applied to low quality images and might not even be suitable for partial fingerprint recognition. To overcome this drawback, in this research, a region-based fingerprint recognition method is proposed in which the fingerprints are compared in a pixel- wise manner by computing their correlation coefficient. Therefore, all the attributes of the fingerprint contribute in the matching decision. Such a technique is promising to accurately recognise a partial fingerprint as well as a full fingerprint compared to the minutiae-based fingerprint recognition methods.The proposed method is based on simple but effective metrics that has been defined to compute local similarities which is then combined into a global score such that it is less affected by distribution skew of the local similarities. Extensive experiments over Fingerprint Verification Competition (FVC) data set proves the superiority of the proposed method compared to other techniques in literature.
Some perspectives on two-dimensional protein mapping. (1984)

Journal Article Some perspectives on two-dimensional protein mapping. Get access L Anderson, L Anderson Search for other works by this author on: Oxford Academic Google Scholar N Anderson N Anderson Search for other works by this author on: Oxford Academic Google Scholar Clinical Chemistry, Volume 30, Issue 12, 1 December 1984, Pages 1898–1905, https://doi.org/10.1093/clinchem/30.12.1898 Published: 01 December 1984
A portable and fault-tolerant microprocessor based on the SPARC v8 architecture (2003)

The architecture and implementation of the LEON-FT processor is presented. LEON-FT is a fault-tolerant 32 bit processor based on the SPARC V8 instruction set. The processors tolerates transient SEU errors by using techniques such as TMR registers, on-chip EDAC, parity, pipeline restart, and forced cache miss. The first prototypes were manufactured on the Atmel ATC35 0.35 /spl mu/m CMOS process, and subjected to heavy-ion fault-injection at the Louvain Cyclotron. The heavy-ion tests showed that all of the injected errors (>100,000) were successfully corrected without timing or software impact. The device SEU threshold was measured to be below 6 MeV while ion energy-levels of up to 110 MeV were used for error injection.
Electroluminescent poly(fluorene-co-thiophene-S,S-dioxide): synthesis, characterisation and structure–property relationshipsElectronic supplementary information (ESI) available: crystal structure of model compound and comparison of its absorption and luminescence spectra. See http://www.rsc.org/suppdata/jm/b2/b208742a/ (2003)

A new copolymer, constituted by the regular alternation of a fluorene derivative with a 1,1-dioxothiophene moiety, has been synthesised via Suzuki coupling. The molecular, thermal, structural, and photophysical characterisations have been performed. The material showed two dimensional order, enhanced by annealing; molecular modelling calculations afforded a consistent structural model accounting for the optical data. In comparison with both polyfluorenes and 1,1-dioxothiophene oligomers the unusual photoluminescence quantum yields observed in solution and in the solid state can be related to a significant contribution of internal conversion to the deactivation process in solution, and the formation of intra-chain hydrogen-bonds, due to a peculiar chain conformation, in the solid state. LED devices based on this new copolymer showed the highest efficiency compared with similar copolymers containing both fluorene and 1,1-dioxothiophene functionalities.
Toward systems that understand spoken language (1994)

MIT's Voyager system is an attempt to explore issues related to a fully interactive spoken-language system and natural language understanding. The system helps users get from one location to another within a specific geographical area, and can provide information about certain objects in the area. The current version of Voyager focuses on the city of Cambridge, Massachusetts, between MIT and Harvard University. Voyager's domain knowledge (or backend) is an enhanced version of an existing direction assistance program (J.R. Davis and T.F. Trobaugh, 1987). The map database includes the locations of various classes of objects (streets, buildings, rivers) and their properties (address, phone number, etc.). To retrieve information, the Summit speech recognition system converts the user's speech signal into a set of word hypotheses, the Tina natural language system interacts with Summit to obtain a word string and a linguistic interpretation of the utterance, and an interface between the two subsystems converts Tina's semantic representation into the appropriate function calls to the back-end. Voyager then responds with a map, highlighting the objects of interest, plus an textual and spoken answer. The current implementation has a vocabulary of about 350 words and can deal with various types of queries, such as the location of objects, simple properties of objects, how to get from one place to another, and the distance and travel time between objects.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Identification of carbohydrate-binding proteins from mouse and human fibroblasts (1983)

Three carbohydrate-binding proteins (Mr 35 000, 16 000 and 13 500) were isolated from extracts of mouse 3T3 fibroblasts by affinity chromatography on polyacrylamide beads to which was covalently bound the ligand 6-aminohexyl 4-beta-D-galactosyl-2-acetamido-2-deoxy-beta-D-glucopyranoside. None of these proteins bind to polyacrylamide beads coupled with either 6-aminohexanol or 6-aminohexyl beta-D-galactopyranoside. Therefore they appear to be carbohydrate-binding proteins specific for galactose-terminated glycoconjugates. A carbohydrate-binding protein was also purified from extracts of human foreskin fibroblasts. This protein (Mr 35000) may represent the human counterpart of the mouse protein of similar Mr and binding properties.
FOREWORD (1996)

ECP (UK) Headquarters, Lady Sobell Gastrointestinal Unit, Wexham Park Hospital, Slough, Berks SL2 4HL, UK, Fax: (+44) 1256 880416
Appendix 9: Glossary of Terms (2011)

The following list of terms and their definitions follows broadly the recommendations made in the fourth edition of the CIE International Lighting Vocabulary (CIE Publication No. 17.4, 1987).The numbers in brackets after the terms indicate the sections in which these terms are discussed. Abney phenomenon (3.4)Change of hue produced by decreasing the purity of a colour stimulus while keeping its dominant wavelength and luminance constant. Abney's Law (2.3)An empirical law stating that if two colour stimuli, A and B, are perceived to be of equal brightness, and two other colour stimuli, C and D, are perceived to be of equal brightness, then the additive mixtures of A with C and B with D will also be perceived to be of equal brightness.(The validity of this law depends strongly on the observing conditions.)absorptance, α (A1.6)Ratio of the absorbed radiant or luminous flux to the incident flux under specified conditions.absorption (13.4) Process by which radiant energy is converted to a different form of energy by interaction with matter.achromatic, colour (1.7) Colour devoid of hue (The names white, grey, black, neutral, and colourless, are commonly used for these colours.)achromatic, signal (1.6 and 15.14) Visual signal from the retina composed of additions of the cone and rod responses.
Thyroid scintigraphy with time-coded aperture. (1979)

Coded aperture imaging (CAI) and multiple-view pinhole imaging (MVPI) of the thyroid were compared in 19 patients to determine whether CAI's theoretical advantages of high resolution, high efficiency, freedom from distortion, accurate size representation, and tomographic presentation could be realized in the clinical setting, and to determine whether CAI offers any advantage over conventional MVPI. The coded aperture images were judged better than the pinhole images in five cases, equal in 13 cases, and worse in one case. The major problem with CAI was the long reconstruction time. Further development and an extended clinical trial appear warranted.
Secure Authentication in Virtual Community by Using Media Access Control address (MAC). (2008)

Abstract ─ The Internet networking is getting more popular in Virtual community which must have a strong security feature to protect member’s privacy and message integrity. Without using a strong security feature in virtual community, virtual community will not accomplish the goal to communicate with members in developing common interests. However, all systems can be hacked, and there are no exceptions to this rule. All security efforts must focus on reducing risks and provide members strong assurance about security. Therefore, physical address-based authentication will improve the trust relationship between members and virtual community.
A Quantitative One-Stage Method for the Assay of Prothrombin (1949)

(1949). A Quantitative One-Stage Method for the Assay of Prothrombin. Scandinavian Journal of Clinical and Laboratory Investigation: Vol. 1, No. 1, pp. 81-83.
Scanning face models with desktop cameras (2001)

Generating face models of humans from video sequences is an important problem in many multimedia applications ranging from teleconferencing to virtual reality. Most practical approaches try to fit a generic face model in the two-dimensional image, and adjust the model parameters to arrive at the final answer. These approaches require the identification of specific landmarks on the face, and this identification routine may or may not be an automated process. In this paper, we present a method for deriving the three-dimensional (3-D) face model from a monocular image sequence, using a few standard results from the affine camera geometry literature in computer vision, and spline-fitting techniques adopted from the nonparametric regression literature in statistics. No prior knowledge of the camera calibration parameters and the shape of the face is required by the system, and the entire process requires no user intervention. The system has been successfully demonstrated to extract the 3-D face structure of humans in several image sequences.
Phosphorus‐31 MR spectroscopy of normal adult human brain and brain tumours (2002)

Localized phosphorus-31 MR spectra were obtained in vivo in a large series of normal human brain tissue specimens of healthy volunteers (n=36) and various brain tumours (n=52). Tumour types examined included grade II and grade III gliomas (n=15 and n=1, respectively), glioblastomas (n=16) and meningeomas (n=12). An additional eight tumours were analysed during chemo- or radiotherapy. Spectra were acquired using a modified ISIS pulse sequence with a repetition time of 3 s. Voxel sizes ranged from 56 to 129 ml. The spectra were evaluated using a least-square variable projection (VARPRO) fitting procedure in the time domain, which allows semi-quantitative determination of relative metabolite concentrations. The measurements in normal cerebrum of healthy volunteers revealed the following results of metabolite signal intensity ratios: pH 7.04 (+/- 0.01), PCr/alpha-ATP 0.51 (+/- 0.03), P(i)/alpha-ATP 0.17 (+/-0.02), PCr/P(i) 2.09 (+/-0.12), PDE/alpha-ATP 3.65 (+/-0.13) and PME/alpha-ATP 0.41 (+/-0.04). Meningiomas showed the most obvious changes when compared with normal brain tissue. They are characterized by an alkaline environment (pH 7.16 +/- 0.03; p<0.005), a decrease in the phosphocreatine peak (p<0.0001) and significantly decreased phosphodiesters (p<0.0001). Glioblastomas also showed alkalization (pH 7.12 +/- 0.02; p<0.001) and a decrease in PDE/alpha-NTP (p<0.05), but no significant changes in PCr/alpha-NTP or PCr/Pi. In gliomas with low malignancy, less distinct changes could be detected with slight alkalization (pH 7.09 +/- 0.02; p<0.05) and more than a two-fold reduction in the PDE/alpha-NTP ratio (p<0.05). The spectra of brain tumours during chemo- and radiotherapy indicated clear but inconsistent influence of the therapy.
Data Sorting in Flash Memory (2015)

Because flash memory now provides an economical solution for various portable devices and embedded systems, an NAND flash-based storage system has replaced the hard disk drive in many applications. Recently, the implementation of database systems using an NAND flash-based storage system has become an important research topic. In particular, the external sorting is an important operation in database systems. With the very distinctive characteristics of flash memory, the typical external sorting system that adopts a clustered sorting process can result in performance degradation and reduce the reliability of flash memory. In this article, we will propose an unclustered sorting method that considers the unique characteristics of flash memory, and we then propose a decision rule to exploit the advantages of both clustered and unclustered sorting. The decision rule can separate records according to their record length, sort them appropriately by the clustered and unclustered sorting, and merge the sorted results. The experimental results show that the proposed method can improve performance in an NAND flash-based storage system (i.e., solid-state drive).