gebhart/patrepeval huggingface dataset:
In Vitro Model of Haemophilus ducreyi Adherence to and Entry into Eukaryotic Cells of Genital Origin (1993)

Electron microscopy was used to examine Haemophilus ducreyi adherence to and entry into eukaryotic cells of genital origin. A clinical H. ducreyi isolate (90-244) adhered in snake-like whorls to the surfaces of cervical carcinoma cells (HeLa 229), endometrial adenocarcinoma cells (HEC-1-B), and human neonatal foreskin fibroblast (HFF) cells. A prototype strain of H. ducreyi (CIP542) adhered in randomly organized clumps on the surfaces of HFF. Strain 90-244 entered HFF and HEC-1-B cells but did not enter HeLa cells. The H. ducreyi in the HFF cells at 2 h were partly surrounded by a membrane consistent with that of a phagocytic vacuole. At 2 h, strain CIP542 was found in interstitial spaces between the HFF cells and also in the cytoplasm of the cells. After 7 and 24 h, both strains of H. ducreyi were found in the large interstitial spaces between the HFF cells, in the cytoplasm, and extracellularly. This model of in vitro H. ducreyi infection of eukaryotic cells will allow for more specific study of factors that determine the virulence of H. ducreyi.
Identification and Characterization of Reconstituted α-Synuclein, Amyloid-β and Tau Fibrils by Immunogold Negative Staining Electron Microscopy (2017)

Neurodegenerative diseases are a major public health concern in the aging population worldwide. Clinically, neurodegeneration manifests as cognitive decline and pathologically by dysfunction and loss of synapses, aggregation of misfolded proteins and progressive neuronal cell loss. The two most common neurodegenerative diseases are Alzheimer's disease, characterized by accumulation of betaamyloid plaques and neurofibrillary tau tangles, and Parkinson's disease, characterized by Lewy Bodies comprised of the protein alpha synuclein. In Alzheimer's disease and Parkinson's disease, the anatomical distribution and burden of tau tangles and synuclein Lewy bodies, respectively, correlate with progression of disease symptoms. These higher order structures of aggregated proteins are believed to originate with misfolded protein monomers that assemble into low molecular weight oligomers, which eventually form protein fibrils
Edge and Cloud-aided Secure Sparse Representation for Face Recognition (2019)

Edge and cloud computing has recently emerged not only to meet the ever-increasing computation demands, but also to provide extra degree of diversity by collecting data from the mobile devices in service. However, this, in turn, has raised new technical challenges on the security issue, and calls for the design of new frameworks to exploit multi-device diversity. In this paper, we take the advantage of this benefit while preserving the privacy. Specifically, 1). To address the privacy issue, we develop a low-complexity encrypting algorithm based on random unitary transform, where it is proved both theoretically and through simulation that such encryption will not affect the result of face recognition. 2). To exploit multi-device diversity, we integrate the recognition results based on the dictionaries of each device into an aggregated output through ensemble learning, which has shown higher correctness of predictability than any individual methods. The designed framework not only contributes to the reduction of computation complexity at each device, but also proves to be effective and robust through simulation results.
The role of IgM and IgG anti-toxoplasma gondii in abortion (1993)

57 women affected by abortion or threatened abortion were investigated in view of antitoxoplasmosis antibodies by immunofluorscence. 11 women who have aborted for the first time have positive titer of polyvalent antibodies more than 1/400. 77.3% of these women have IgM titer greater than 1/20. The highest percentage of abortion was in the third month of pregnancy and this is probabley related to the increase in the percentage of women who have IgM titer greater than 1/20 and who were in the acute stage of the disease. The percentage of women with a positive titer of IgM titer greater than 1/20 and who were in the acute stage of the disease. The percentage of women with a positive titer of IgM of greater than 1/20 decreased from the third month of pregnancy. It seems that the care and follow-up of pregnant women with toxoplasmosis whether from antibody titer or from its type is of great importance. It is preferable to titrate antitoxoplasmosis antibody titers in the sera of women before pregnancy.
An Experimental Investigation Into the Relationship Between Temperature-Time History and Surface Roughness in the Spray Quenching of Aluminum Parts (1996)

Repeated heat-quench cycles of Al-1100 samples resulted in increased surface roughness and corresponding shifts in the temperature-time cooling curve towards shorter overall quench periods. Three different types of initial surface roughness were applied to the test samples: polished, particle blasted, and milled finishes. For each of the three test surfaces, cooling curve shifts during repeated heat-quench cycles were accompanied by surface roughening, the shift was smallest with the milled sample. The surface roughness was examined with the aid of scanning electron microscopy, surface contact profilometry, and X-ray photoelectron spectroscopy. Surface profiles obtained via the profilometer revealed, on a relative basis, significant changes in surface roughness on the polished and particle blasted surfaces but not on the milled (roughest) surface. The roughening was the result of (a) hydrogen diffusion associated with oxidation, (b) oxidation buildup, and, to a lesser extent, (c) expulsion of impurities along dendrite boundaries. The hydrogen diffusion caused localized pressure buildup within the surface and along grain boundaries resulting in the formation of both microscopic (1 to 10 μm) features on the polished and particle blasted surfaces and relatively large (20 to 1000 μm) bumps and blisters on the particle blasted surface. It is shown how these wide spectrum surface roughness features affect cooling rate by (a) raising the Leidenfrost temperature separating the film and transition boiling regimes, (b) increasing the number of boiling sites on the quenched surface, and (c) altering the impact dynamics of the spray drops.
Functional Group Distributions on Mesoporous Silica (2011)

Most applications of mesoporous silica require some degree of functionalization. The surface of porous materials can be divided into external and internal (pore) surfaces, and in many cases, a selective functionalization of these surface subsections is desired. This short review outlines our recent work in this field and focuses on the postsynthetic functionalization of mesoporous silica with aminopropylalkoxysilanes and on the analysis of the respective functional group distributions by confocal laser scanning microscopy. Methods to obtain an amino-functionalized external surface and functional group gradients on the pore surface are reported. Arrays of silica nanochannels (ASNCs) serve as a model system for mesoporous silica.
Can Laparoscopic Hernia Repair Alter Function and Volume of Testis? (2003)

Testicular atrophy is a sequela of inguinal hernioplasty. The purpose of this study was to evaluate the effects of Lichtenstein (LHR) and laparoscopic totally extraperitoneal (TEP) hernia repair techniques on testicular function and volume. This study is a randomized prospective clinical trial with the blind assessment of outcome. A total of 26 patients who underwent elective herniorrhaphy for groin hernia were included in the study. Each patient was randomly assigned into one of two groups: either TEP or LHR (n = 13 for each). Six of the patients had bilateral hernia (n = 3 for each group). Luteinizing hormone (LH), follicle stimulating hormone (FSH), testosterone levels, and testicular volume by Doppler ultrasonography were detected just before and 3 months after the operation. LH, FSH levels did not change, when compared preoperative and postoperatively in both groups. Testicular volume and testosterone levels were observed to be significantly decreased after TEP when compared with LHR while no significant preoperative changes were observed between those groups. This affected the testicular volume in normal limits. TEP or LHR could not affect LH, FSH, testosterone values, but TEP could lead a decreasing effect on volume of testis in normal limits.
Optimisation de programmes par reconnaissance de templates (2005)

Most compiler optimizations apply local transformations on the code, without knowing the computation expressed by the program. Despite the performance obtained, the best the solution remains to call hand-optimized libraries. Learning and using a performance is a fastidious and bug-prone task. In this thesis, we propose to deleguate this task to the compiler. Given a program, this thesis propose a compiler algorithm able to (i) recognize programs slices realizing an algorithm and to (ii) substitute a program slice by a call to a performance library whenever it is possible and profitable. Ouralgorithm is able to detect all the program slice equivalent to the seeked algorithm with respect to Herbrand equivalence, a subset of program equivalence which ignore semantic properties of arithmetic operators. In addition to functions, we are able to find template instances in a program. Such a feature makes possible to find call sites to a template library. Our approach has been implementd in the tool TeMa (Template Matcher) and applied to the detection of functions from the BLAS library (Basic Linear Algebra Subroutines) in the kernels from the benchmarks SpecFP 2000 et Perfect Club. In particular, experimental results show a substantial speedup on the kernels swim, mgrid and applu.
Chaos in Human Behavior: The Case of Work Motivation (2010)

This study considers the complex dynamics of work motivation. Forty-eight employees completed a work-motivation diary several times per day over a period of four weeks. The obtained time series were analysed using different methodologies derived from chaos theory (i.e. recurrence plots, Lyapunov exponents, correlation dimension and surrogate data). Results showed chaotic dynamics in 75% of cases. The findings confirm the universality of chaotic behavior within human behavior, challenge some of the underlying assumptions on which work motivation theories are based, and suggest that chaos theory may offer useful and relevant information on how this process is managed within organizations.
Autologous Non-Myeloablative Hematopoietic Stem Cell Transplantation for Diffuse Scleroderma. (2005)

Abstract Background &Aims Scleroderma is an immune mediated vasculopathy of unknown etiology. There is no known therapy that could alter the natural course of the disease. Patients with diffuse cutaneous disease or visceral involvement has an overall 10-year survival of 35 to 68%. Autologous hematopoietic stem cell transplantation (HSCT) with myeloablative regimen has been performed, but with substantial mortality and morbidity especially pulmonary and renal toxicity. We have performed autologous HSCT utilizing non-myeloablative, but lymphoablative conditioning. Methods We conducted a phase 1 HSCT study in 9 patients with diffuse scleroderma with poor clinical features. Candidates were less than 65 years old with Rodman score of more than 14 or diffusion capacity less than 80%, interstitial lung disease, elevated ESR, renal involvement, or abnormal electrocardiogram. Patients with pulmonary hypertension (systolic pressure > 45 mm Hg) were excluded. Peripheral blood stem cells were mobilized with cyclophosphamide and granulocyte colony-stimulating factor. The graft was not manipulated. The conditioning regimen consisted of 200mg/kg cyclophosphamide (CY), and 7.5mg/kg rabbit antithymocyte globulin (ATG). Results The procedure was well tolerated with anticipated cytopenias, neutropenic fever, and fluid overload that were easy to manage and without mortality. The median days for neutrophil and platelet engraftment were 8 (range 7–9) and 8 (range 0–10), respectively. The median infused CD34+ and CD3+ cell counts were 8.31 x 106/kg (range 2.35–14.7) and 2.03 x 108/kg (range 0.41–6.83), respectively. There was a marked improvement of skin score in all subjects, whereas cardiac (ejection fraction, pulmonary arterial pressure), pulmonary function (DLCO) and renal function (creatinine) remained stable. One patient with advanced disease with poor performance status died 2 years after the transplant with progressive disease. After median follow-up of 20 months (range 5–32), the overall survival is 89% (eight out of nine) and progression-free survival with continuing improvement is 67% (six out of nine. 2 patients developed recurrence of skin tightness without compromising organ function. Both of them were placed on mycophenolate mofetil with gradual improvement of skin tightness. Conclusion Autologous HSCT with CY/ATG is safe and is effective. A randomized study (ASSIST: American Scleroderma Stem Cell vs. Immune Suppression Trial), comparing HSCT to intravenous pulse cyclophosphamide is now enrolling patients. Figure Figure
Robust compressive sensing of sparse signals: a review (2016)

Compressive sensing generally relies on the ℓ 2 norm for data fidelity, whereas in many applications, robust estimators are needed. Among the scenarios in which robust performance is required, applications where the sampling process is performed in the presence of impulsive noise, i.e., measurements are corrupted by outliers, are of particular importance. This article overviews robust nonlinear reconstruction strategies for sparse signals based on replacing the commonly used ℓ 2 norm by M-estimators as data fidelity functions. The derived methods outperform existing compressed sensing techniques in impulsive environments, while achieving good performance in light-tailed environments, thus offering a robust framework for CS.
THE ANTIBACTERIAL EFFECT OF SELECTED PHENOTHIAZINES AND THIOXANTHENES ON SLOW‐GROWING MYCOBACTERIA (1986)

The aim of the present investigation was to illustrate the antibacterial effect of various phenothiazine and thioxanthene derivatives on mycobacteria in vitro. It was demonstrated that clopenthixol is about twice as potent as chlorpromazine (CPZ) and levomepromazine-maleate is about half as potent as CPZ, measured by the inhibitory effect on the growth of the mycobacterial strains. Measured in the same way the stereoisomeric compounds of flupenthixol are shown to be more potent than the stereo-isomeric compounds of clopenthixol and chlorprothixen. The two last-named compounds are equal in potency. The stereo-isomeric analogs of the thioxanthene derivatives are equal in antibacterial potency against the slow-growing mycobacteria. The mycobacterial strains investigated show no difference in sensitivity between the cis (Z)--and and trans (E)--compounds of the thioxanthenes. It seems particularly promising that also the more resistant mycobacteria other than Mycobacterium tuberculosis, e.g. M. avium and M. intracellulare, are sensitive in the concentration range investigated. Considered as a whole, these results might be a stimulus to investigate the antimicrobial effect of the thioxanthenes in vivo.
Patterned grafting of acrylic acid onto polymer substrates (2008)

Abstract Polyethylene films were irradiated through a mask with high‐energy argon ions to activate the surface for grafting. Acrylic acid was graft polymerized onto the irradiated region of the polyethylene surface. The grafted surface was characterized by using FT‐IR and XPS. Patterned grafting of acrylic acid on the polyethylene surface was finally confirmed by a fluorescence labeling method. Copyright © 2008 John Wiley & Sons, Ltd.
Currently available methods of industrial nanodiamond synthesis (2004)

The main theoretical aspects of detonation decomposition of powerful mixed explosives with a negative oxygen balance accompanied by the formation of nanodiamonds (ultrafine-dispersed diamonds, UDDs) are described. The basic UDD synthesis parameters are considered, and the expediency of using trotyl-hexogen alloys is shown. The conditions of diamond phase conservation in the detonation products are specified. Various versions of industrial detonation synthesis of UDDs are considered. The most efficient technology of chemical cleaning of UDDs (with nitric acid at high temperatures and pressures) for producing UDDs with the highest purity is described.
Optical Rotation of Peptides. IV. Lysine Tripeptides<sup>1</sup> (1951)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTOptical Rotation of Peptides. IV. Lysine Tripeptides1Erwin Brand, Bernard F. Erlanger, Jerome Polatnick, Howard Sachs, and Donald KirschenbaumCite this: J. Am. Chem. Soc. 1951, 73, 8, 4027–4028Publication Date (Print):August 1, 1951Publication History Published online1 May 2002Published inissue 1 August 1951https://pubs.acs.org/doi/10.1021/ja01152a520https://doi.org/10.1021/ja01152a520research-articleACS PublicationsRequest reuse permissionsArticle Views59Altmetric-Citations12LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Lubricants, 5. Gear Lubrication Oils (2011)

Abstract The article contains sections titled: 1. Introduction 2. Requirements of Gear Lubrication Oils 3. Tribology of Gears 3.1. Friction Conditions of Gear Types 3.2. Specific Gear and Transmission Failure 4. Gear Lubrication Oils for Motor Vehicles 4.1. Lubricants for Gear Drives in Commercial Vehicles 4.2. Lubricants for Gear Drives in Passenger Cars 4.3. Lubricants for Automatic Transmissions and CVTs 5. Multipurpose Lubricants in Vehicle Gears 6. Gear Lubricants for Industrial Gears
Diavik waste rock project : thermal transport in a covered waste rock test pile (2011)

Covers are widely used in the management of mine tailings and waste rock and most current cover designs and constructions are in temperate regions. However in cold regions, certain features and processes are unique and they can be utilized to reduce the production of acid rock drainage (ARD). An field study of the thermal behaviour of an experimental covered waste rock pile in a continuous permafrost region is presented. The results indicate that a till unit within the cover remains at sub zero temperatures. The study found that the mean annual heat flux at the base of the layer was significantly less than at the surface due heat retention in the cover and soil saturation levels. The ratio of net radiation to surface heat flux is high and this is common for bare soil surfaces.[All papers were considered for technical and language appropriateness by the organizing committee.]
Chapter 10. On-line and Off-line MALDI from a Microfluidic Device (2008)

Micro total analysis systems (μTAS) are novel platforms that address the need for high-throughput and automated analysis achieved through miniaturization, integration and multiplexing of processing and analysis elements.1–4 Integration of sample processing steps reduces analysis time and prevents sa...
Mechanism of insulin-induced activation of Na(+)-K(+)-ATPase in isolated rat soleus muscle (1991)

Insulin augments Na(+)-K(+)-ATPase activity in skeletal muscles. It has been proposed that the sequence of events is activation of Na(+)-H+ antiporter, increased intracellular Na+ concentration ( [Na+]i), and stimulation of Na(+)-K+ pump. We have used isolated rat soleus muscles to test this hypothesis. Insulin increased the ouabain-suppressible K+ uptake in a dose- and time-dependent manner. The maximal effect was observed at 50-100 mU/ml insulin. Stimulation of K+ uptake was accompanied by increased specific [3H]ouabain binding and lowered [Na+]i. The ionophore monensin, which promotes Na(+)-H+ exchange, also increased the rate of ouabain-suppressible K+ uptake in soleus muscle, with a maximal effect obtained at 10-100 microM ionophore. However, this increase was accompanied by an elevation of [Na+]i. In the presence of 10-100 microM monensin, addition of 100 mU/ml insulin further increased K+ uptake but reduced [Na+]i. The effect on K+ uptake was additive. Ouabain (10(-3) M) completely suppressed the effect of insulin on [Na+]i. Insulin had no effect on the magnitude or the time course of insulin stimulation of K+ uptake. Thus equal stimulation of Na(+)-K(+)-ATPase by insulin was observed when [Na+]i was elevated (under monensin) or lowered (under amiloride). These data suggest that activation of Na(+)-K(+)-ATPase in soleus muscle by insulin is not secondary to stimulation of Na(+)-H+ antiporter.
A double‐blind study of the speed of onset of analgesia following intramuscular administration of ketorolac tromethamine in comparison to intramuscular morphine and placebo (1991)

A double-blind, randomised, parallel group, placebo-controlled study was performed in 85 patients to compare the speed of onset of analgesia following the intramuscular administration of a single dose of 30 mg of ketorolac tromethamine, 10 mg of morphine or placebo. A new, sensitive, method was used to measure the latency of analgesia. The onset of analgesia was defined by the time taken for the pain intensity score to reach a specified percentage of the baseline value. Twenty-five percent of patients achieving a 50% reduction in baseline pain intensity score appears to be the most appropriate parameter to assess the speed of onset of analgesia of ketorolac and morphine in the postoperative setting. Paired comparison demonstrated that ketorolac had a significantly faster onset of analgesia (p = 0.03) when compared to placebo, whilst comparison of morphine to placebo analgesic latency (p = 0.06) just failed to reach significance. There was no significant difference between the analgesic onset time of ketorolac and morphine (p = 0.73). Intramuscular ketorolac and intramuscular morphine have comparable analgesic onset times in the postoperative pain context. However, the sensitive method of measuring onset of analgesia described, highlights the slow onset of analgesia when analgesics of known efficacy are given by the intramuscular route in the postoperative period. More attention should be given to the speed of onset of analgesia in future assessments of analgesics.