gebhart/patrepeval huggingface dataset:
An Approach To Identifying Geological Properties From Roof Bolter Drilling Parameters (1900)

Identifying the properties of overlying rocks in underground mining operations is important to ensure the appropriate roof support design is used to maintain stability of the mine entries. Recently J. H. Fletcher & Co. developed a monitoring and control system for roof bolters for the underground mining industry. The system records the drilling parameters used during roof bolt drilling and the information can provide insight into the physical properties of the roof strata. The parameters include thrust, rotational speed, torque and velocity and the measurements are collected every 0.1 second during the operation. The drilling parameters were analyzed to determine the application of identifying the strength of rocks being drilled from the measurements. The data was converted into the specific energy of drilling which is a measure of the amount of energy required for removing a given unit of rock during a drilling operation. The laboratory studies completed to date indicate a fairly high correlation between the specific energy of drilling and the unconfined compressive strength of ihe rocks that were drilled. Additionally, the drilling parameters were shown to be effective for identifying the presence of fractures or bed separations between rock layers. The thrust, torque and specific energy of drilling were all good indicators for identifying the fractures or separations. Regardless of the drilling parameters used during the drilling experiments, the location of the fractures were identified. In order to determine the application of the drilling parameters for identifying roof rock properties, two series of experiments were conducted. The first series of experiments used three roof layers that had various rock samples embedded in concrete blocks. The rock samples included three types of sandstone, marble, and argillite. Another concrete block was poured with foam inserts to simulate large bedding separations (2 to 8-in). Two other manufactured blocks were constructed using high-strength concrete with cardboard layers Gene Wilson, New Product Development Manager J.H. Fletcher & Company Huntington, WV Bob Thomas, President Structured Mining Systems Canonsburg, PA embedded to simulate smaller fractures or bedding separations. The size of the cardboard layers varied from 1/8to 1-in thick. One of the blocks had the cardboard layers embedded at an inclined angle to determine the effect of the orientation on the drilling parameters. A series of experiments was conducted with the rotational speed and the penetration rate held constant and the thrust and torque allowed to vary. The information collected from the experiments is used to determine the application of the drilling parameter measurements for identifying rock properties, fractures and bedding separations.
A structural study of 3- and 4-iodosylbenzoic acids, 3- and 4-iodylbenzoic acids, and their sodium salts (1990)

The 13C NMR, IR, and UV spectra of 3- and 4-iodobenzoic, 3- and 4-iodosylbenzoic, and 3- and 4-iodylbenzoic acids and their sodium salts have been measured and compared with those of the corresponding 2-isomers. Kinetic data for the catalytic microemulsion hydrolysis of 4-nitrophenyl diphenyl phosphonate in the presence of the iodosyl and iodyl compounds have been obtained. Catalytic efficiency of the 3- and 4-substituted isomers are measured to be three to six orders of magnitude less effective than the corresponding 2-substituted isomers. Possible structural configurations are suggested and discussed.
Near-optimal energy transitions for energy-state trajectories of hypersonic aircraft (1992)

A problem of the instantaneous energy transition that occurs in energy-state approximation is considered. The transitions are modeled as a sequence of two load-factor bounded paths (either climb-dive or dive-climb). The boundary-layer equations associated with the energy-state dynamic model are analyzed to determine the precise location of the transition.
WINTER CROPS AS BIOASSAYS OF SOIL NITROGEN-SUPPLYING CAPACITY (2011)

Soil nitrogen (N)-supplying capacity bioassays could present alternatives to traditional soil tests. Objectives were to identify winter crops and associated characteristics with bioassay potential. Saint Joseph and Bossier City, LA experiments used randomized complete block designs with factorial N fertilizer and winter crop treatment arrangements. Nitrogen rates were applied to corn (Zea mays L.) in 2004. Unfertilized winter wheat ( Triticum aestivum L.), cereal rye (Secale cereale L.), native winter vegetation, and weed-free winter fallow treatments followed corn. At Saint Joseph, cotton (Gossypium hirsutum L.) followed winter crop treatments. Greater corn N rate consistently increased winter crop biomass and N accumulation, suggesting potential as bioassays, and increased Saint Joseph seedcotton yield. Winter crop-seedcotton yield N-response relationships were non-significant by familywise error rate criteria. However, some winter crop characteristics, such as rye N accumulation, for which a relationship to seedcotton yield closely approached significance, may merit further research as soil N-supplying capacity bioassays.
Effects of Actinomycete Secondary Metabolites on Sediment Microbial Communities (2016)

Ocean sediments represent one of Earth's largest and most poorly studied biomes. These habitats are characterized by complex microbial communities where competition for space and nutrients can be intense. This study addressed the hypothesis that secondary metabolites produced by the sediment-inhabiting actinomycete Salinispora arenicola affect community composition and thus mediate interactions among competing microbes. Next-generation amplicon sequencing of mesocosm experiments revealed complex communities that shifted following exposure to S. arenicola extracts. The results reveal that certain predatory bacteria were consistently less abundant following exposure to extracts, suggesting that microbial metabolites mediate competitive interactions. Other taxa increased in relative abundance, suggesting a benefit from the extracts themselves or the resulting changes in the community. This study takes a first step toward assessing the impacts of bacterial metabolites on sediment microbial communities. The results provide insight into how low-abundance organisms may help structure microbial communities in ocean sediments.
Size effects in the structural phase transition of<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mrow><mml:msub><mml:mrow><mml:mi mathvariant="normal">VO</mml:mi></mml:mrow><mml:mrow><mml:mn>2</mml:mn></mml:mrow></mml:msub></mml:mrow></mml:math>nanoparticles (2002)

We have observed size effects in the structural phase transition of submicron vanadium dioxide precipitates in silica. The ${\mathrm{VO}}_{2}$ nanoprecipitates are produced by the stoichiometric coimplantation of vanadium and oxygen and subsequent thermal processing. The observed size dependence in the transition temperature and hysteresis loops of the semiconductor-to-metal phase transition in ${\mathrm{VO}}_{2}$ is described in terms of heterogeneous nucleation statistics with a phenomenological approach in which the density of nucleating defects is a power function of the driving force.
The High Resolution Doppler Imager (1991)

Get PDF Email Share Share with Facebook Tweet This Post on reddit Share with LinkedIn Add to CiteULike Add to Mendeley Add to BibSonomy Get Citation Copy Citation Text Vincent J. Abreu, Paul B. Hays, and Wilbert R. Skinner, "The High Resolution Doppler Imager," Optics & Photonics News 2(10), 28-30 (1991) Export Citation BibTex Endnote (RIS) HTML Plain Text Citation alert Save article
The Study on the Correlation between Traffic Signal Location and Stop Line Observance (2007)

The Korea National Police Agency launched a campaign to encourage drivers in stop line observance and to discourage stop line violation by intensively imposing fines. It was to increase stop line observance of drivers and thus traffic safety. According to statistics, the stop line observance rate was increased over 80 % of drivers during the campaign but regressed to the past after the campaign. This paper delivers the effect of the location of traffic signal lights on driver's stop line observance and develops a guideline to improve highway traffic environment in long terms. Statistical tests conducted based on field data showed that the drivers' stop line observance increases when traffic signal lights are closely installed from a stop line. It was proposed from the study that traffic signal lights be installed from a stop line.
Regulation of glycogen synthesis by the laforin–malin complex is modulated by the AMP-activated protein kinase pathway (2007)

Lafora progressive myoclonus epilepsy (LD) is a fatal autosomal recessive neurodegenerative disorder characterized by the presence of glycogen-like intracellular inclusions called Lafora bodies. LD is caused by mutations in two genes, EPM2A and EPM2B, encoding respectively laforin, a dual-specificity protein phosphatase, and malin, an E3 ubiquitin ligase. Previously, we and others have suggested that the interactions between laforin and PTG (a regulatory subunit of type 1 protein phosphatase) and between laforin and malin are critical in the pathogenesis of LD. Here, we show that the laforin-malin complex downregulates PTG-induced glycogen synthesis in FTO2B hepatoma cells through a mechanism involving ubiquitination and degradation of PTG. Furthermore, we demonstrate that the interaction between laforin and malin is a regulated process that is modulated by the AMP-activated protein kinase (AMPK). These findings provide further insights into the critical role of the laforin-malin complex in the control of glycogen metabolism and unravel a novel link between the energy sensor AMPK and glycogen metabolism. These data advance our understanding of the functional role of laforin and malin, which hopefully will facilitate the development of appropriate LD therapies.
Prevention of LPS-Induced Microglia Activation, Cytokine Production and Sickness Behavior with TLR4 Receptor Interfering Peptides (2013)

The innate immune receptor Toll-like 4 (TLR4) is the receptor activated by lipopolysaccharide (LPS), and TLR4-LPS interaction is well known to induce an innate immune response, triggering sickness behavior. Within the brain, TLR4 is highly expressed in brain microglia, and excessive inflammation resulting from activation of this pathway in the brain has been implicated in depressive disorders and neurodegenerative pathologies. We hypothesized that blocking LPS-induced activation of TLR4 would prevent downstream immune signaling in the brain and suppress the induction of sickness behavior. We used interfering peptides to block TLR4 activation and confirmed their efficacy in preventing second messenger activation and cytokine production normally induced by LPS treatment. Further, these peptides blocked morphological changes in microglia that are typically induced by LPS. We also demonstrated that intraperitoneal (i.p.) injection of Tat-TLR4 interfering peptides prevented LPS-induced sickness behavior, as assessed in home cage behavior and with the intracranial self-stimulation paradigm. These newly synthesised peptides inhibit TLR4 signaling thereby preventing changes in behavior and motivation caused by inflammatory stimuli. These peptides highlight the roll of TLR4 and microglia morphology changes in sickness behavior, and thus may be of therapeutic value in limiting the deleterious impact of excessive inflammation in specific CNS pathologies.
[Synthesis of thiophene and alpha-terthiophene derivatives with antiproliferative activity]. (2005)

We have synthesised a series of known alpha-terthiophene lead molecules with PKC (protein kinase C) inhibitory activity and the compounds were tested in cell proliferation assay on EGF-RTK (epidermal growth factor receptor protein tyrosine kinase) over-expressing tumour cell line (A431). We found that two of them had excellent antiproliferative activity. We prepared a focused molecule library around the thiophene and the terthiophene scaffold and examined these compounds in cell proliferation assay on A431.
17—THE COMPRESSION OF YARNS PART II: THE LOAD-COMPRESSION RELATION (1981)

By using the compression-energy function derived in Part I, the relation between the compressive force and the deformation it produces is derived. The theoretical result is compared with some experimental data.
Pathophysiological studies of trinitrobenzene sulfonic acid-induced colitis in Syrian hamsters (Mesocricetus auratus). (2005)

We developed a colitis model in Syrian hamsters (Mesocricetus auratus) to investigate the relationship between colitis and neutrophil elastase (NE). Colitis was induced by a single intracolonic dose of trinitrobenzene sulfonic acid (TNBS; 90 mg/ml) dissolved in 15% (vol/vol) ethanol. The ulcer area, tissue myeloperoxidase (MPO) activity, and luminal NE activity all were increased on Days 1 and 5, corresponding with the acute inflammatory histopathological changes. These acute inflammatory parameters subsequently decreased by Day 14, and chronic inflammatory histopathological changes became evident. Recurrence of inflammation was not observed during the period up to Day 28. To evaluate our colitis model, the effects of prednisolone were examined. Prednisolone was administered orally once on the day before induction of colitis, and animals were treated twice daily thereafter. Although prednisolone had little effect on the tissue MPO activity, prednisolone inhibited the ulcer area and NE activity. In addition, the effects of an NE-specific inhibitor (ONO-6818) on our TNBS-induced colitis model were examined. In the subcutaneous treatment study, ONO-6818 was administered once before the induction of colitis. Although ONO-6818 had little effect on the tissue MPO activity, the ulcer area and NE activity were decreased in the ONO-6818-treated group. The inhibitory effects on the ulcer area and NE activity were confirmed after oral treatment with ONO-6818 after induction of colitis. We conclude that our colitis model is useful for investigating the relationship between colitis and NE, and inhibition of NE activity can prevent the progression of ulceration.
Improve the Accuracy of Impedance Imaging in Electrical and Ultrasonic Multi-imaging System (2017)

The purpose of this study is to make a proposal for a simple and non-invasive irradiation positioning technique in the heavy particle beam therapy. For this purpose, we propose a method of using electric and ultrasonic multi imaging. Features of the proposed method, by simultaneous imaging of ultrasound and electric characteristics in the same space, with only ultrasound imaging is that changes in can not be found properties will be able to discover. This paper attempts to imaging of the tumor area by computer simulation in the model close to a living body. Furthermore, the diagnostic ultrasound system estimating the structure of the body, proposes a method of setting the initial value of the impedance imaging tailored to its composition, we report confirmed its usefulness.
Precisely-Controlled Frequency Agile Laser for Radio Frequency Spectral Analysis (2005)

Get PDF Email Share Share with Facebook Tweet This Post on reddit Share with LinkedIn Add to CiteULike Add to Mendeley Add to BibSonomy Get Citation Copy Citation Text G. Gorju, V. Crozatier, V. Lavielle, F. Bretenaker, I. Lorgeré, and J. Le Gouët, "Precisely-Controlled Frequency Agile Laser for Radio Frequency Spectral Analysis," in Advanced Solid-State Photonics, Technical Digest (Optica Publishing Group, 2005), paper TuB35. Export Citation BibTex Endnote (RIS) HTML Plain Text Citation alert Save article
Impact of Surfactants on the Performance of “Green Additives” as Calcium Carbonate Inhibitors for Aqueous Systems (2013)

Abstract The inhibition of calcium carbonate (CaCO 3 ) precipitation by “green” additives has been examined in aqueous solution. It has been found that additive performance as CaCO 3 inhibitor depends upon additive architecture. The influence of surfactants containing different functional group has also been investigated. Results on the evaluation of surfactants suggest that compared to carboxyl group containing additives, surfactants are ineffective CaCO 3 inhibitors. Performance data on the impact of cationic surfactant (e. g., cetyltrimethyl ammonium chloride, CTAC) suggest that CTAC exhibits an antagonistic effect on the performance of polymers. The antagonistic behavior shown by CTAC on the performance of additives has been explained in terms of cationic – anionic interactions. SEM study shows that presence of low concentration of additive exhibits marked influence on the morphology of CaCO 3 crystals formed in presence of additives.
Recent Results from the Experimental Evaluation of the Learnable Evolution Model (2002)

The Learnable Evolution Model (LEM) represents a form of non-Darwinian evolutionary computation that is guided by a learning system. Specifically, LEM "genetically engineers" new populations via hypothesis formation and instantiation. This paper presents results from new studies in which LEM was systematically tested on a range of optimization problems and a complex real world design task. The study involved LEM2, a new implementation oriented toward function optimization, and LEMd-ISHED, an implementation oriented toward engineering design. LEM2 strongly outperformed tested evolutionary algorithms in terms of the evolution length, measured by the number of fitness function evaluations needed to reach the solution. This evolutionary speedup also translated to an execution speedup whenever the fitness evaluation time was above a small threshold (a fraction of a second). Experiments with LEMd-ISHED on problems of optimizing heat exchangers (evaporators) produced designs that matched or exceeded designs produced by human experts.
Simple model for carrier densities in the depletion region of p-n junctions (1993)

By applying the concepts of carrier velocity saturation, and electron-hole pair generation and recombination, in concert with the standard textbook derivation of the p-n abrupt junction diode equations, an analytic expression is found for the magnitude of the carrier densities near and through the depletion region of abrupt p-n junctions. The analytic expression is useful for determining carrier-density or recombination-dependent processes within the depletion region. The derivation is based on the assumption that electrons and holes pass through the depletion region at the saturation velocity. The analytic expression is compared to S-PISCES 2B simulation in a specific silicon-p-n junction. The model is called VESAT to indicate its dependence on carrier velocity saturation.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
ChemInform Abstract: Titanium(III)‐Mediated Synthesis of a 1,2,3‐Tricarbonyl Moiety from an α‐Oximido β‐Keto Ester: Application to the Synthesis of the Carbacephem Nucleus. (1992)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Demountable vacuum seals for fusion reactor applications (1987)

Demountable vacuum seals for fusion reactor applications must be compatible with the reactor environment, easily scalable, very reliable and readily maintained by remote handling methods. We are investigating gate valves as well as flanges in our efforts to provide such seals. They are all metal and scalable without becoming massive and require no axial fasteners. Preliminary tests on an initial 30 cm aluminum flange using no soft metal coatings or gaskets have given several vacuum tight closures. Weld fatigue of this preliminary design caused degradation of the seal with further cycling to leakage levels of 10/sup -6/ Tl/sec, which is acceptable with differential pumping for either valves or flanges. Additional flange pairs using slightly altered geometry, fabrication techniques, and seal plating materials will be tested and reported on.
Regulation of protein <scp>l</scp>-isoaspartyl methyltransferase by cell–matrix interactions: involvement of integrin αvβ3, PI 3-kinase, and the proteasome (2006)

The enzyme L-isoaspartyl methyltransferase (PIMT) is known to repair damaged proteins that have accumulated abnormal aspartyl residues during cell aging. However, little is known about the mechanisms involved in the regulation of PIMT expression. Here we report that PIMT expression in bovine aortic endothelial cells is regulated by cell detachment and readhesion to a substratum. During cell detachment, the PIMT level was rapidly and strongly increased and correlated with a stimulation of protein synthesis. Aside from endothelial cells, PIMT levels were also regulated by cell adhesion in various cancer cell lines. The upregulation of PIMT expression could be prevented by an anti-alphavbeta3 antibody (LM609) or by a cyclic RGD peptide (XJ735) specific to integrin alphavbeta3, indicating that this integrin was likely involved in PIMT regulation. Moreover, we found that PIMT expression returned to the basal level when cells were replated on a substratum after detachment, though downregulation of PIMT expression could be partly prevented by the PI3K inhibitors LY294002 and wortmannin, as well as by the proteasome inhibitors MG-132, lactacystin, and beta-lactone. These findings support the assumption that the PIMT level was downregulated by proteasomal degradation, involving the PI3K pathway, during cell attachment. This study reports new insights on the molecular mechanisms responsible for the regulation of PIMT expression in cells. The regulation of PIMT level upon cell-substratum contact suggests a potential role for PIMT in biological processes such as wound healing, cell migration, and tumor metastasis dissemination.
Bilinear modelling and bilinear PI control of directional drilling (2016)

This paper presents the design of an inclination- and azimuth-hold controllers and their subsequent stability and performance analysis for directional drilling tools as typically used in the oil industry. Using an input transformation developed in earlier work that partially linearizes and decouples the plant dynamics of the directional drilling tool, a bilinear model of the directional drilling tool is developed and is used as the basis for Bilinear PI controller design. Results for a transient simulation of the proposed BPI controller are presented and compared with that of the PI controller of the earlier work. It is presented that BPI controller gives more consistent responses over a broader operating range compared to the PI controller. In addition, the effect of time delay on the feedback measurements with respect to the stability and performance is investigated in the simulations.
Nonlinear ionic pseudopotentials in spin-density-functional calculations (1982)

A new method for generating and using first-principles pseudopotentials is developed to treat explicitly the nonlinear exchange and correlation interaction between the core and the valence charge densities. Compared to existing potentials, the new scheme leads to significant improvement in the transferability of the potential. In particular, the spin-polarized configurations are well described with a single potential. The need for separate spin-up and spin-down ionic pesudopotentials is, thus, eliminated. The method can easily be implemented with minimal increase in computational effort. Results for both atoms and solids are demonstrated.