gebhart/patrepeval huggingface dataset:
Evaluation of Patellofemoral Contact Mechanics as a Function of Quadriceps Load and Flexion Angle (2012)

Patellofemoral complications are the single largest reason for knee related clinical visits. In spite of this, development of robust clinical treatments in this area remains a challenge [1]. Quantifying joint response across a wide range of conditions may lead to interventions specifically targeting desired or “normal” function. Previous patellofemoral studies often looked at joint mechanics as a function of specific quadriceps loaded flexion (e.g. deep knee bend) and/or during snapshots of loading representative of lifelike scenarios, e.g. gait, stair climb, etc. [2]. Sensitivity studies have been performed for these expected conditions [3,4] providing insight on the relationship between joint loading, geometry and potential contact mechanics. While patellofemoral biomechanics studies are prevalent, few, if any, have attempted to quantify joint response to systematic changes of two of the primary indicators of joint mechanics, namely quadriceps load and knee flexion. The overall joint response resulting from this type of approach could help quantify an envelope of natural function and also serves as an ideal data set for future computational model development. Once developed, probabilistic exploration of inherent uncertainties could be accomplished through a complimentary in vitro and in silico approach, offering quantification and classification of structure-function relationships. As a preliminary step, the goal of this study was to relate in vitro joint response, in terms of kinematics and contact mechanics, to systematic changes in knee flexion angle and quadriceps loading for a single specimen. Results from this study will offer insight into patellofemoral mechanics across a range of expected input and also serves as a starting point for future hypothesis driven studies.
Correlation properties of direct broadcast signals for bistatic remote sensing (2012)

In this paper, we present a study of relevant correlation properties of signals transmitted from commercial DirecTV satellite signals with the purpose of evaluating their potential use as “signals of opportunity” for bistatic remote sensing. The ambiguity function of the DirecTV satellite signal is computed analytically from published information on the modulation schemes and bandwidth, under the assumption that the data modulation is random. This model is experimentally tested by recording the received signals from the satellites. Also, the signal to noise ratio (SNR) is computed from the published information. The coherence time of the DirecTV signal is computed using the experimental data from two direct signals that is recorded with two different clock sources. An experiment is done to record some reflected data from a river and the coherence time of the Interferometric Complex Field (ICF) from this reflected data is computed for the purposes of measuring the sea state.
Metallic conductivity versus charge disproportionation in C <sub>60</sub> complexes with noninteger average charges on fullerene (2016)

Abstract Oxidation of {cryptand(Na + )}(C 60 •‐ ) and {cryptand(Na + )} 2 (C 60 2− ), which display integer −1 and −2 charges on the fullerene unit, by iron(II) octaethyltetrapyrazinoporphyrazine allowed the crystallization of complexes with noninteger average charges on C 60 . The complex {cryptand(Na + )}(C 60 ) 3 ‐ ⋅2C 6 H 4 Cl 2 ( 1 ), with a partial charge of ‐0.33 on C 60 , exhibits a closely‐packed 3D structure formed by fragments of hexagonal fullerene layers. Complex 1 shows high conductivity in the 295–120 K range: conductivities of 50–60 and 100–250 S⋅cm −1 were measured using four‐probe and microwave techniques, respectively. Metallic behavior of 1 is observed down to 150–120 K. Metallic conductivity is still observed in 1 after one month of exposure to air. The complexes {cryptand(Na + )}(C 60 ) 2 − ( 2 ) and {cryptand (Na + )} 8 (C 60 ) 6 8− ( 3 ), which display average charges of −0.5 and −1.33, respectively, on C 60 , do not show metallic conductivity. This can be explained by charge disproportionation and the formation of neutral and −1‐charged C 60 in 2 , and −1‐ and −2‐charged C 60 in 3 . Despite the close packing of the fullerene molecules in crystal structures, no dimerization of C 60 is observed in 1 and 2 . On the contrary, diamagnetic, singly‐bonded (C 60 − ) 2 dimers are formed in {cryptand(Li + )} 2 (C 60 − ) 2 ⋅C 6 H 4 Cl 2 ⋅C 6 H 14 ( 4 ), which contains fullerene molecules bearing a full −1 charge.
Languages for multi-database interoperability (1997)

article Free Access Share on Languages for multi-database interoperability Authors: Frédéric Gingras Department of Computer Science, Concordia University, Montreal, Quebec, Canada Department of Computer Science, Concordia University, Montreal, Quebec, CanadaView Profile , Laks V. S. Lakshmanan Department of Computer Science, Concordia University, Montreal, Quebec, Canada Department of Computer Science, Concordia University, Montreal, Quebec, CanadaView Profile , Iyer N. Subramanian Department of Computer Science, Concordia University, Montreal, Quebec, Canada Department of Computer Science, Concordia University, Montreal, Quebec, CanadaView Profile , Despina Papoulis Department of Computer Science, Concordia University, Montreal, Quebec, Canada Department of Computer Science, Concordia University, Montreal, Quebec, CanadaView Profile , Nematollaah Shiri Department of Computer Science, Concordia University, Montreal, Quebec, Canada Department of Computer Science, Concordia University, Montreal, Quebec, CanadaView Profile Authors Info & Claims ACM SIGMOD RecordVolume 26Issue 2June 1997pp 536–538https://doi.org/10.1145/253262.253397Published:01 June 1997Publication History 8citation369DownloadsMetricsTotal Citations8Total Downloads369Last 12 Months24Last 6 weeks3 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Publisher SiteeReaderPDF
Identifying Rogating Blades Vibration From the Shaft Torsional Vibration Signals (2003)

This paper presents results from an experimental study on the identification of rotating blades vibration from the shaft torsional vibration signals. Test rigs that contain 12 blades bladed disk with shaft equipped with lateral and torsional vibration measurement is designed and manufactured. Start-up and steady state operational conditions are experimentally simulated. The results from two blades strain gages and the rotor lateral and torsional vibration measurements showed that the blades vibration signatures can be identified effectively from the shaft torsional vibration signals. More sensitive shaft torsional vibration signals to blades vibration are shown for closer torsional vibration measurement from the bladed disk. Moreover, the shaft torsional vibration signals can be more representative of blades vibration if the 1X rotor vibration due to unbalance is filtered out.
KINETIC ANALYSES OF THE ACTIVATION OF GLU-PLASMINOGEN BY TISSUE PLASMINOGEN ACTIVATOR IN THE PRESENCE OF FIBRIN, FIBRINOGEN, FRAGMENTS D AND E (1987)

Kinetic analyses were made for the activation of Glu-plg (Glu-plasminogen) by tissue plasminogen activator (t-PA: two chain t-PA obtained from Bowes melanoma cell line) in the presence of fibrin, fibrinogen, fragment D or E. Glu-plg was activated by t-PA in the presence of various concentrations of fibrinogen, fibrin, fragment D or E, and the activation rate was measured by the hydrolysis of S-2251 with plasmin generated. Straight Line-weaver-Burk plots were obtained by changing the concentration of Glu-plg. In the absence of fibrin, t-PA activated Glu-plg with Km of 1.11 μM, kcat of 0.005 sec-1, kcat/Km of 0.0045 μM-1,sec-1. The presence of catalytic amounts (0.0001 μM) of fibrin resulted in 11.4 fold decrease in Km, thus 15.6 fold increase in kcat/Km. The presence of larger amounts of fibrin resulted in increase in kcat and decrease in Km, which resulted in 142 fold increase in kcat/Km. There seems to be two phases in the enhancement of the activation of Glu-plg by t-PA, one induced in the presence of catalytic amounts of fibrin, and the other induced in the presence of higher concentration of fibrin (up to 0.05/0.2 of the molar ratio of fibrin to plasminogen). When effects of fragment D or E were examined for the enhanced activation of Glu-plg by t-PA, the presence of increasing amounts of E resulted in increase in kcat. Presence of D resulted in increase in kcat and decrease in Km. Since plasminogen was shown to bind to both D and E domains of fibrin, and t-PA was shown to bind to D domain, we hypothesize that the role of D in the activation of Glu-plg by t-PA was to provide a site to t-PA and plasminogen to form a ternary complex, which facillitates the activation of plasminogen by t-PA, and that the role of E was to provide a site to bind to plasminogen, where t-PA activates plasminogen more effectively. The results suggest that roles of D and E domains of fibrin may be different in the enhanced activation of plasminogen by t-PA.
Multiple Coupled Resonator Power Supply (2007)

Summary form only given. Dc and ac high voltages have been generated by "air core" transformers dating back to Tesla and Abramyan. At North Star Power Engineering (NSPE), we have used "air core" transformers to build both dc accelerators and dc power supplies. Recently we developed a technique to efficiently "relay" or transfer magnetic flux through a series of coils in which the coils are not in any way physically connected with one another. The coils are arranged so that each couples strongly to many of its neighbors and each has its own resonating capacitor. For these reasons we have named it a Multiple Coupled Resonator (MCR). The MCR concept lends itself to a variety of applications due to its unique nature including power transfer, high voltage ac and high voltage dc. The first application of this technique is the production of dc high voltage in an air at 150 kV and in SF6 at 200 kV and 10 mA. A design for a 600 kV version of this supply, which is applicable to irradiation, ion acceleration, capacitor bank charging, and a variety of other applications, has been developed. We believe that this technology will find application in power supplies operating from 100 s of kV up to several MeV and kilowatts of output power.
Improving Design Diversity Using Graph Based Evolutionary Algorithms (2006)

Graph based evolutionary algorithms (GBEAs) have been shown to have superior performance to evolutionary algorithms on a variety of evolutionary computation test problems as well as on some engineering applications. One of the motivations for creating GBEAs was to produce a diversity of solutions with little additional computational cost. This paper tests that feature of GBEAs on three problems: a real-valued multi-modal function of varying dimension, the plus-one-recall-store (PORS) problem, and an applied engineering design problem. For all of the graphs studied the number of different solutions increased as the connectivity of the graph underlying the algorithm decreased. This indicates that the choice of graph can be used to control the diversity of solutions produced. The availability of multiple solutions is an asset in a product realization system, making it possible for an engineer to explore design alternatives.
Faulty Operations of a PM Fractional-Slot Machine With a Dual Three-Phase Winding (2010)

The permanent-magnet (PM) machine with dual three-phase windings is proposed for applications requiring continuous operating even under a partial fault. The two windings are supplied by two separate inverters. Thus, in the event of a fault of one winding, this is disconnected, and the machine continues to be operated by means of the healthy winding. This paper investigates the PM machine with dual three-phase windings and its capabilities during faulty operating conditions. A fractional-slot interior PM machine with 12 slots and 10 poles is taken into account. Its performance is investigated according to different winding configurations. The torque behavior, overload capability, and thermal limits are evaluated under open-circuit and short-circuit faults. A finite-element analysis as well as experimental tests is carried out on a prototype of such a machine.
[2-(<i>tert</i>-Butylcarbonylmethylamino)phenyl]acetic acid (2002)

We present here the crystal structure of the title comp­ound, C14H19NO4. It contains O⋯H—O and N⋯H—O hydrogen bonds, connecting the mol­ecules into centrosymmetric dimers and into infinite chains.
Chemokine receptor expression in rat adjuvant‐induced arthritis (2005)

These findings show that 1) constitutive expression of CCR1 on macrophages remains high during AIA; 2) CCR2 and CCR3 may play a role in initial recruitment of leukocytes to ST in AIA; 3) macrophage expression of CCR2 and CCR5 may be important for sustaining inflammatory changes; and 4) EC CXCR4 may be a harbinger of inflammatory changes. Our results may help guide chemokine receptor blockade-targeting treatment strategies in inflammatory arthritis.
PKCε modulates NF-κB and AP-1 via mitogen-activated protein kinases in adult rabbit cardiomyocytes (2000)

We have previously shown that protein kinase C (PKC)-epsilon, nuclear factor (NF)-kappaB, and mitogen-activated protein kinases (MAPKs) are essential signaling elements in ischemic preconditioning. In the present study, we examined whether activation of PKCepsilon affects the activation of NF-kappaB in cardiac myocytes and whether MAPKs are mediators of this signaling event. Activation of PKCepsilon (+108% above control) in adult rabbit cardiomyocytes to a degree that has been previously shown to protect myocytes against hypoxic injury increased the DNA-binding activity of NF-kappaB (+164%) and activator protein (AP)-1 (+127%) but not that of Elk-1. Activation of PKCeta did not have an effect on these transcription factors. Activation of PKCepsilon also enhanced the phosphorylation activities of the p44/p42 MAPKs and the p54/p46 c-Jun NH(2)-terminal kinases (JNKs). PKCepsilon-induced activation of NF-kappaB and AP-1 was completely abolished by inhibition of the p44/p42 MAPK pathway with PD98059 and by inhibition of the p54/p46 JNK pathway with a dominant negative mutant of MAPK kinase-4, indicating that both signaling pathways are necessary. Taken together, these data identify NF-kappaB and AP-1 as downstream targets of PKCepsilon, thereby establishing a molecular link between activation of PKCepsilon and activation of NF-kappaB and AP-1 in cardiomyocytes. The results further demonstrate that both the p44/p42 MAPK and the p54/p46 JNK signaling pathways are essential mediators of this event.
Mechanical model for the shear strength prediction of corrosion-damaged reinforced concrete slender and non slender beams (2021)

Steel corrosion in RC structures leads to a reduced reinforcement area, changes in steel mechanical properties, cracking and, eventually, concrete cover spalling, among other phenomena. Stirrups are generally small in diameter and, given their small concrete cover, they are more susceptible to corrosion than longitudinal reinforcement. Hence their corrosion significantly affects shear strength. Most existing models that deal with reduction in the shear strength of corrosion-damaged reinforced concrete (RC) structures are empirical; that is, they have been numerically fitted to test results. In this context, conceptual models based on structural mechanics principles and verified for corrosion-damaged members are still needed. In this paper, the Compression Chord Capacity Model (CCCM), a shear mechanical model previously derived by the authors, is adapted to predict the shear strength of corrosion-damaged RC beams. For this purpose, the model parameters that can be affected by steel corrosion in RC beams were identified and modified accordingly. CCCM predictions were compared to the experimental results of 146 slender and non slender beams failing in shear, in which stirrups and/or longitudinal reinforcement was subjected to corrosion. The CCCM achieved very satisfactory shear strength predictions when reductions in reinforcement areas and web width were taken into account, with a mean value of the Vtest/Vpred ratio equaling 1.19 and a 19.5% coefficient of variation. Finally, a parametric analysis was performed to show the predicted reductions in shear strength according to the CCCM compared to the experimental results of some especially relevant tests.
Low-Energy Electron Diffraction, X-ray Photoelectron Spectroscopy, and CO-Temperature-Programmed Desorption Characterization of Bimetallic Ruthenium−Platinum Surfaces Prepared by Chemical Vapor Deposition (2001)

Low-energy electron diffraction (LEED), X-ray photoelectron spectroscopy (XPS), and CO-temperature-programmed desorption (TPD) were used to characterize ruthenium-modified Pt(100) surfaces of very high purity and controlled stoichiometry prepared in ultrahigh vacuum (UHV) by irradiating Ru3(CO)12 films condensed on cold Pt substrates at 150 K with X-rays, and subsequent annealing at ca. 620 K. The presence of Ru on Pt(100) lifted the (5 × 20) reconstruction characteristic of the bare clean substrate; however, the reconstruction reappeared as the bimetallic surfaces were briefly annealed to ca. 900 K. Exposure of nonannealed Ru(θRu ≥ 0.22)/Pt(100), where θRu represents the Ru coverage in monolayers, to large exposures of CO at ca. 200 K yielded smaller θCO, as well as TPD peaks with onset desorption temperatures, Tdes(CO), ca. 50 K lower than those observed for bare Pt(100). More strikingly, however, the CO-TPD spectra of CO-saturated Ru(θRu = 0.42)/Pt(100), which had been briefly annealed to 900 K, displayed Tdes(CO) as low as 250 K, very similar to desorption temperatures reported for Pt-modified Ru(0001) by de Mongeot et al. (Surf. Sci. 1998, 411, 249).
Management in biophotonics and biotechnologies (2005)

Biophotonics, one of the most exciting and rapidly growing areas, offers vast potential for changing traditional approaches to meeting many critical needs in medicine, biology, pharmacy, food, health care and cosmetic industries. Follow the market trends we developed new MSc course Management in Biophotonics and Biotechnologies (MBB) that provide students of technical disciplines with the necessary training, education and problem-solving skills to produce professionals and managers who are better equipped to handle the challenges of modern science and business in biophotonics and biotechnology. A major advantage of the course is that it provides skills not currently available to graduates in other Master programs.
Evaluation of Milk Fat-Globule Membrane (MFGM) Emulsion for Oral Administration: Absorption of .ALPHA.-Linolenic Acid in Rats and the Effect of Emulsion Droplet Size. (1994)

The performance of milk fat-globule membrane (MFGM) emulsion as an oral dosage form was evaluated in rats using [14C]alpha-linolenic acid as a lipophilic model solute. For emulsions prepared by homogenization alone, the area under the plasma concentration versus time curve (AUC) after oral administration tended to be larger for MFGM emulsion, 35.0 +/- 2.5 micrograms eq.h/ml (mean +/- S.E., n = 3), than for Tween 80 emulsion, 28.5 +/- 0.6 micrograms eq.h/ml at p < 0.1, though the peak plasma concentration (Cmax) and the time required to reach Cmax (Tmax) were not significantly different. The absorption in the intestinal loop was not significantly different between the two emulsions, either. Thus, MFGM emulsion, compared with Tween 80 emulsion, did not show an obvious advantage or enhancement in the oral and intestinal absorption of alpha-linolenic acid, except for a slight increase in AUC. However, MFGM could be a good alternative to a synthetic emulsifier for oral use, considering that it is of natural origin and may be safer. In addition, it was shown that the AUC, as well as the absorption in the intestinal loop, was decreased for a MFGM emulsion in which the droplet size was reduced by sonication, presumably because of the observed decrease in alpha-linolenic acid concentration in the water phase, which was assumed to be the result of an increased distribution of alpha-linolenic acid, due to its amphipathic nature, to the increased oil-water interface.
Effect of using a Bi_12SiO_20 light amplifier on the formation and competition of modes in optical resonators (1986)

The transverse modes of an oscillator of which the active medium is a Bi12SiO20 (BSO) crystal are expected to be different from those of the passive resonator and of a laser because of the properties of light amplification by photorefractive effect. The experimental study described here demonstrates the possibility of high-diffraction-loss resonators by using a BSO amplifier and illustrates the multimode operation of such an oscillator, according to the Fresnel-number value.
O0036 COMMON FEATURES OF GUT DEVELOPMENT AND NEOPLASIA REFLECTED BY NPO GENE EXPRESSION (2004)

Introduction: Molecular control of growth and morphogenesis during intestinal development is poorly understood. Previously, the NIL PER OS (NPO) gene was found to be essential to the endoderm-intestine transition in zebrafish (1). Loss of NPO function leads to a hypoplastic, poorly developed intestine, and its overexpression causes hyperproliferation of intestinal epithelium. These data suggest the hypothesis that NPO acts to specify intestinal epithelial progenitors cells. The aim of this study is to determine the pattern of NPO expression in developing, adult, and neoplastic intestine. Since the progenitor cell compartment of the intestine is spatially distinct, expression of NPO in this compartment, and promiscuous expression in tumors would be consistent with our hypothesis. Methods: We used staged mouse embryos and discarded human surgical specimens of colon cancer, polyp and adult normal tissue to study NPO expression by in situ hybridization. Cultured colon cancer cells (caco-2) were subjected to RT-PCR analysis to determine NPO expression levels as a function of their differentiation state. Results: We found that expression of NPO during mouse development is dynamic, similar to that in zebrafish. As the villi form, diffuse NPO expression in the unpatterned endoderm becomes progressively restricted to a subset of intestinal epithelial cells that are located in the the intervillous regions, and then in the crypts of Lieberkuhn of the adult. We also examined NPO expression in human colon carcinoma, which exhibits many features of crypt cells. Indeed, NPO was expressed at a much higher level in neoplastic compared to normal tissue. Using the caco-2 cell model, we found that the NPO expression level declined markedly upon confluence-induced differentiation. Conclusion: Our data suggest that NPO may play a role in specifying epithelial progenitor cells in several different contexts: during development, homeostasis and neoplasia. Further study will be needed to determine if NPO is functionally required for each of these processes. The npo protein binds RNA and is thought to be involved in ribosomal biogenesis (2,3). Thus regulation of ribosomal biogenesis by NPO may play a role in progenitor cell specification.