gebhart/patrepeval huggingface dataset:
MITOTIC ACTIVITY OF IMMUNOLOGICALLY COMPETENT LYMPHOID CELLS TRANSFERRED INTO X-IRRADIATED RECIPIENTS (1962)

A study was made to ascertain whether mitotic activity in cell transfer sites could be readily observed by colchicineinduced mitotic arrest, and, if so, whether the rate of division would be sufficient to indicate that antibody- containing cells could develop from a relatively small number of precursors in a manner similar to that in the intact animal. The results showed that antibody production in the cell transfer system is preceded by significant mitotic activity of the transferred lymphoid cells. Lymph node cells were obtained from rabbits immunized by repeated injections of bovine serum albumin (BSA) or bovine gamma -globulin (BGG). Two days before the transfer experiment, recipient rabbits were x irradiated (400 r, total-body) to suppress their immune response, and 100 to 150 million cells were injected subcutaneously into each of three different sites in the abdominal wall; thus, a total of approximates 400 million cells were transferred to each animal. Immediately after transfer, 1.5 mg I/sup 131/-BSA or 2.5 mg I/sup 131/BGG were injected intravenously into the corresponding recipients. Cells in the connective tissue of the injection sites were examined 1-7 days later, morphologically, and by immunofluorescence for the presence of antibody. The results showed that there is amore » line of cytologic development in the cell transfer site leading to the appearance of the typical plasma cell; this cell and its younger precursors contain antibody. Another line of cytologic development was also present, leading to the formation of a cell resembling superficially plasma cells, but differing from them in size, structure of the nucleus, absence of perinuclear halo, and pale cytoplasm. This cell does not contain antibody. The origin of the antibody-containing cell in the transfer system was traced to the transferred sensitized cells. By use of colchicine to arrest mitosis for 2 hr, it was possible to detect a significant mitotic activity in the cell transfer sites. The observed mitotic rates indicate that from l day to 4 days after transfer and antigenic stimulation the cells presumably capable of division (large and medium lymphoid cells) did divide once or twice per 24-hr period. Similar mitotic rates were observed in lymphoid tissue in the intact animal during an antibody response. Therefore, the antibody-containing cells observed in transfer sites from the fifth day on may have been derived from any cell type capable of division, including the blast cells. It is concluded that these antibody-containing cells in cell transfer sites could be derived from precursors through successive divisions, and that in the cell transfer system, antibody production is preceded by mitotic activity of the transferred lymphoid cells in a manner similar to that of the lymphoid tissue of the intact animal. (BBB)« less
An Open Device Driver Architecture for Direct Machining and Control (2005)

Computer-Aided Design and Applications is an international journal on the applications of CAD and CAM. It publishes papers in the general domain of CAD plus in emerging fields like bio-CAD, nano-CAD, soft-CAD, garment-CAD, PLM, PDM, CAD data mining, CAD and the internet, CAD education, genetic algorithms and CAD engines. The journal is aimed at all developers and users of CAD technology to ptovide CAD solutions for various stages of design and manufacturing. The journal publishes all about Computer-Aided Design and Computer-Aided technologies.
Efficient chaotic-driven echo path modelling (1995)

An efficient coding strategy is proposed that enables optimal echo path modelling of a speech telephony circuit. Original experimental results show that the proposed strategy improves the modelling convergence rate on noise-impaired circuits while using conventional real-time least-mean-square (LMS) digital adaptive filter (DAF) configurations.
ChemInform Abstract: DE NOVO SYNTHESIS OF CARBOHYDRATES AND RELATED NATURAL COMPOUNDS. PART 4. TOTAL SYNTHESIS OF 2,5‐DIAMINO‐2,5‐DIDEOXYRIBOSE (1980)

Abstract Die aus den Komponenten (I) und (II) erhältlichen Cycloaddukte (III) werden in die Derivate (V) übergeführt; Verseifung von (Va) mit methanolischer KOH gibt ein Gemisch der Isomeren (VIa) + (VIb), analoge Verseifung von (Vb) dagegen nur ein Produkt (VII).
Precipitation of group V elements and Ge in SiO2 and their drift in a temperature gradient (1988)

It is shown that P, Sb, and Ge ions implanted in SiO2 precipitate into spherical clusters of up to 1000 Å diameter when heat treated in an oxygen-free ambient. This behavior is similar to that reported earlier for As implants. The clusters can be detected directly by transmission electron microscopy, or inferred from the unidirectional drift of the doped zone in a temperature gradient. Boron, a representative of group III, is the only element among those tested that does not migrate in a ∇T, suggesting the absence of phase separation.
Ion beam techniques in archaeology and the arts (1983)

The authors present a review of ion beam techniques for use in archaeology (age estimation) and analysis of cultural objects.
A buffer-based baseband analog front end for CMOS bluetooth receivers (2002)

A CMOS low-power baseband analog front end (BAFE) for an integrated bluetooth receiver is presented. The BAFE is designed using a new fully differential buffer (FDB) circuit that can effectively implement filters with gain/filtering interleaved operations. The BAFE utilizes five FDB circuits to implement a sixth-order low noise high linear prefilter, a sixth-order MOS-C tunable filter and a variable gain amplifier (VGA). The distribution of gain and filtering between the various blocks simplifies the design of the VGA stages and allows a good compromise between the input referred noise and the overall linearity. The analog front end is fabricated using a regular 1.2-/spl mu/m CMOS process and occupies an area of 1.7 mm /spl times/ 1.7 mm. Measurements results indicate that the total standby current consumption is less than 2.4 mA while providing a gain control range from 12-30 dB in 6-dB step. The input referred noise is less than 42 nV//spl radic/(Hz) and the out-of-band IIP3 of more than 12 dBm.
Interspecies “Transfer” of Delayed Hypersensitivity <i>In Vitro</i> with Rna Extracts (1970)

Abstract When nonsensitive guinea pig peritoneal exudate cells (PEC) were incubated in vitro with RNA extracts from rhesus monkeys with delayed sensitivity to purified protein derivative (PPD) alone, or PPD and coccidioidin, the PEC were inhibited in their migration from capillary tubes in the presence of specific antigen. These data suggest that interspecies conversion of “nonsensitive” guinea pig PEC to “sensitive” cells was accomplished with monkey RNA extracts.
Sensing Characteristics of Chemical Agents by Using Liquid Crystal-Based Chemical and Biological Sensors (2010)

This paper reports the design of a microstructure comprising an interdigitated capacitance structure for the detection of vapor-phase analytes based on nematic liquid crystal (NLC) sensor. The NLC sensor is tested by using demethyl-methylphosphonate (DMMP) detection to change the orientational response of the liquid crystal molecules and demonstrated by the optical monitoring as well as the capacitive monitoring. Finally, vapor-phase analyte concentrations down to the parts-per-billion (ppb) level have been tested.
Femtoscopy with identified charged pions in proton-lead collisions at <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:mrow><mml:msqrt><mml:msub><mml:mi>s</mml:mi><mml:mi mathvariant="italic">NN</mml:mi></mml:msub></mml:msqrt><mml:mo>=</mml:mo><mml:mn>5.02</mml:mn></mml:mrow></mml:math> TeV with ATLAS (2017)

Bose-Einstein correlations between identified charged pions are measured for p+Pb collisions at s NN = 5.02 TeV using data recorded by the ATLAS detector at the CERN Large Hadron Collider corresponding to a total integrated luminosity of 28 nb -1 . Pions are identified using ionization energy loss measured in the pixel detector. Two-particle correlation functions and the extracted source radii are presented as a function of collision centrality as well as the average transverse momentum (k T ) and rapidity (y ) of the pair. Pairs are selected with a rapidity -2 < y < 1 and with an average transverse momentum 0.1 < k T < 0.8 GeV. The effect of jet fragmentation on the two-particle correlation function is studied, and a method using opposite-charge pair data to constrain its contributions to the measured correlations is described. The measured source sizes are substantially larger in more central collisions and are observed to decrease with increasing pair k T . A correlation of the radii with the local charged-particle density is demonstrated. The scaling of the extracted radii with the mean number of participating nucleons is also used to compare a selection of initial-geometry models. The cross term R ol is measured as a function of rapidity, and a nonzero value is observed with 5.1 combined significance for -1 < y < 1 in the most central events.
Properties of Concrete with Tire Derived Aggregate Partially Replacing Coarse Aggregates (2015)

Tire derived aggregate (TDA) has been proposed as a possible lightweight replacement for mineral aggregate in concrete. The role played by the amount of TDA replacing coarse aggregate as well as different treatment and additives in concrete on its properties is examined. Conventional concrete (without TDA) and concrete containing TDA are compared by examining their compressive strength based on ASTM C39, workability based on ASTM C143, splitting tensile strength based on ASTM C496, modulus of rupture (flexural strength) based on ASTM C78, and bond stress based on ASTM C234. Results indicate that while replacement of coarse aggregates with TDA results in reduction in strength, it may be mitigated with addition of silica fume to obtain the desired strength. The greatest benefit of using TDA is in the development of a higher ductile product while utilizing recycled TDA.
Modification of Pyruvate Kinase Activity by Proteins from Chicken Liver (1979)

The partial purification of a protein fraction inhibiting pyruvate kinase isoenzymes is described. The fraction was isolated from the (NH4)2SO4 step of the purification procedure for pyruvate kinase isoenzymes from chicken liver (Eigenbrodt, E. & Schoner, W. (1977) Hoppe-Seyler's Z. Physiol. Chem. 358, 1033-1046) by extraction with 1N NaOH, acidification to pH 3, ethanol precipitation and chromatography of the supernatant on DEAE-cellulose. The inhibitor fraction was further purified by disc gel electrophoresis using a gel gradient from 10 to 25%; this procedure separated activating proteins from the inhibitor fraction. The inhibitor fraction inhibited the pyruvate kinase isoenzymes from chicken in the sequence of decreasing effect: M2 greater than L greater than M1. The inhibition was due to a decrease in the affinity for phosphoenolpyruvate. The inhibitor is stable against heating for 5 min in 1% sodium dodecyl sulfate at 100 degrees C; it is destroyed by pepsin digestion. The inhibitor fraction could be purified further only by dodecyl sulfate gel electrophoresis. This resulted in the separation of 2 inhibitors (Mr = 33,500 +/- 8500 and ca. 5000), an activator (Mr = 15,100 +/- 5200), and an unidentified protein (Mr = 27,000).
Energy Gap in Nuclear Matter (1960)

The magnitude of the energy gap in nuclear matter associated with a highly correlated ground state of of the type believed to be important in the theory of superconductivity has been evaluated theoretically. The integral equation of Cooper, Mills, and Sessler is linearized and transformed into a form suitable for numerical solution. The energy gap, calculated by using an appropriate single-particle potential and the Gammel-Thaler two-body potential, is found to be a very strong function of the density of nuclear matter, and of the effective mass at the Fermi surface. It is concluded that the magnitude of the energy gap for nuclear matter should not be compared directly with experimental values for finite nuclei, although the results suggest that if the theory is extended to apply to finite nuclei it probably would be in agreement with experiment.
Development of an Equine Behavior Chamber and Effects of Amitraz, Detomidine, and Acepromazine on Spontaneous Locomotor Activity (1997)

The locomotor chamber is a sensitive and highly reproducible tool for measuring spontaneous locomotor activity in the horse. It allows investigators to determine an agent’s average time of onset, duration, and intensity of effect on movement. Authors’ addresses: Maxwell H. Gluck Equine Research Center and the Department of Veterinary Science, University of Kentucky, Lexington, KY 40506 (Harkins and Tobin) and Universidade Estadual Paulista, Campus de Jaboticabal, Brazil (Queiroz-Neto). r 1997 AAEP.
Effect of thiamine pyrophosphate on ischemia-reperfusion induced oxidative damage in rat kidney (2013)

It has been shown that thiamine pyrophosphate prevents increase in mutagenic DNA in IR induced oxidative damage, whereas thiamine does not have this effect.
TRANSURETHRAL ULTRASOUND GUIDED APPLICATION OF AUTOLOGOUS MYO- AND FIBROBLASTS IN TREATMENT OF INCONTINENCE IN WOMEN: 2 YEAR DATA (2008)

You have accessJournal of Urology1 Apr 2008TRANSURETHRAL ULTRASOUND GUIDED APPLICATION OF AUTOLOGOUS MYO- AND FIBROBLASTS IN TREATMENT OF INCONTINENCE IN WOMEN: 2 YEAR DATA Hannes Strasser, Michael Mitterberger, Orietta Dalpiaz, Andrea Kerschbaumer, Ferdinand Frauscher, Rainer Marksteiner, Eva Margreiter, and Georg Bartsch Hannes StrasserHannes Strasser More articles by this author , Michael MitterbergerMichael Mitterberger More articles by this author , Orietta DalpiazOrietta Dalpiaz More articles by this author , Andrea KerschbaumerAndrea Kerschbaumer More articles by this author , Ferdinand FrauscherFerdinand Frauscher More articles by this author , Rainer MarksteinerRainer Marksteiner More articles by this author , Eva MargreiterEva Margreiter More articles by this author , and Georg BartschGeorg Bartsch More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(08)61569-4AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "TRANSURETHRAL ULTRASOUND GUIDED APPLICATION OF AUTOLOGOUS MYO- AND FIBROBLASTS IN TREATMENT OF INCONTINENCE IN WOMEN: 2 YEAR DATA." The Journal of Urology, 179(4S), p. 534 © 2008 by American Urological AssociationFiguresReferencesRelatedDetails Volume 179Issue 4SApril 2008Page: 534 Advertisement Copyright & Permissions© 2008 by American Urological AssociationMetrics Author Information Hannes Strasser More articles by this author Michael Mitterberger More articles by this author Orietta Dalpiaz More articles by this author Andrea Kerschbaumer More articles by this author Ferdinand Frauscher More articles by this author Rainer Marksteiner More articles by this author Eva Margreiter More articles by this author Georg Bartsch More articles by this author Expand All Advertisement PDF downloadLoading ...
Development and validation of a prototype 16S rRNA‐based taxonomic microarray for <i>Alphaproteobacteria</i> (2005)

The microarray approach has been proposed for high throughput analysis of the microbial community by providing snapshots of the microbial diversity under different environmental conditions. For this purpose, a prototype of a 16S rRNA-based taxonomic microarray was developed and evaluated for assessing bacterial community diversity. The prototype microarray is composed of 122 probes that target bacteria at various taxonomic levels from phyla to species (mostly Alphaproteobacteria). The prototype microarray was first validated using bacteria in pure culture. Differences in the sequences of probes and potential target DNAs were quantified as weighted mismatches (WMM) in order to evaluate hybridization reliability. As a general feature, probes having a WMM > 2 with target DNA displayed only 2.8% false positives. The prototype microarray was subsequently tested with an environmental sample, which consisted of an Agrobacterium-related polymerase chain reaction amplicon from a maize rhizosphere bacterial community. Microarray results were compared to results obtained by cloning-sequencing with the same DNA. Microarray analysis enabled the detection of all 16S rRNA gene sequences found by cloning-sequencing. Sequences representing only 1.7% of the clone library were detected. In conclusion, this prototype 16S rRNA-based taxonomic microarray appears to be a promising tool for the analysis of Alphaproteobacteria in complex ecosystems.
Beyond Heart Sounds: an interactive teaching and skills testing program for cardiac examination (2002)

Cardiac examination and auscultation are skills that are not adequately taught in training programs, and as a result are poorly performed by trainees in internal medicine and cardiology. In an attempt to address these deficiencies, the authors have videotaped bedside physical findings along with stethoscopic heart sound recordings in over 100 patients with "classical" forms of heart disease, and have developed a series of interactive multimedia programs designed to be used in training programs for medical students and residents. The programs have tutorial as well as skills-testing content. Formal evaluation of the program's ability to teach cardiac examination skills is under way. Preliminary results from third-year medical students before and after training with software showed a significant improvement (P=0.02). After training, these students tested at the level of first-year cardiology fellows.
Photoluminescent Determination of the Fundamental Gap for the Ferromagnetic Semiconductor Cd<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mrow><mml:msub><mml:mrow><mml:mi mathvariant="normal">Cr</mml:mi></mml:mrow><mml:mrow><mml:mn>2</mml:mn></mml:mrow></mml:msub></mml:mrow></mml:math><mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mrow><mml:msub><mml:mrow><mml:mi mathvariant="normal">Se</mml:mi></mml:mrow><mml:mrow><mml:mn>4</mml:mn></mml:mrow></mml:msub></mml:mrow></mml:math> (1981)

Photoluminescence has been used to elucidate the electronic structure of the ferromagnetic semiconductor Cd${\mathrm{Cr}}_{2}$${\mathrm{Se}}_{4}$. Luminescence spectra and decay have been measured and analyzed as a function of temperature and the quantum efficiency has been determined at 77 K. The data indicate that the observed emission results from conduction-band to valence-band transitions and place the fundamental gap at 1.8 eV.
Genetic Predisposition to Fiber Carcinogenesis Causes a Mesothelioma Epidemic in Turkey (2006)

Malignant mesothelioma in the western world is often associated with asbestos exposure. It is a relatively rare cancer that causes approximately 2,500 deaths yearly in the United States and 1,000 deaths yearly in the United Kingdom. In contrast, among people born in the Cappadocian (Turkey) villages of Tuzkoy, Karain, and "Old" Sarihidir, approximately 50% of deaths are caused by malignant mesothelioma. This epidemic has been attributed to erionite exposure, a type of fibrous zeolite mineral commonly found in this area of Turkey. In these three villages, malignant mesothelioma occurs in certain houses but not in others. The hypothesis was that a unique and more carcinogenic erionite was present in certain houses and caused malignant mesothelioma. We determined the X-ray diffraction pattern and the crystal structure of erionite from malignant mesothelioma villages and compared the results with the erionite samples from nearby non-malignant mesothelioma villages and from the United States. We found the same type of erionite in Cappadocian villages, with or without a malignant mesothelioma epidemic, in households with high or no incidence of malignant mesothelioma and in the United States. Pedigree studies of the three malignant mesothelioma villages showed that malignant mesothelioma was prevalent in certain families but not in others. When high-risk malignant mesothelioma family members married into families with no history of it, malignant mesothelioma appeared in the descendants. Genetically predisposed family members born and raised outside the malignant mesothelioma villages did not seem to develop malignant mesothelioma. In summary, pedigree and mineralogical studies indicate that the malignant mesothelioma epidemic is caused by erionite exposure in genetically predisposed individuals. This is the first time that genetics is shown to influence mineral fiber carcinogenesis.
The clinical grading of lens opacities (1989)

A simple system has been developed for the clinical grading of the presence and severity of lens opacities. The densities of nuclear opacities as seen on clinical slit-lamp examination are graded in comparison with a set of standard photographs. The extent of cortical opacities seen on retroillumination is estimated in terms of segments involved. The dimensions of posterior subcapsular opacities are measured using the slit beam. Inter- and intraobserver trials were conducted with three observers. Twenty subjects were selected to provide a range of lens opacities. Weighted Kappa statistics for intraobserver agreement for these three types of opacities range between 0.58 and 1.00 and for interobserver agreement between 0.41 and 0.71. This clinical grading system shows good reproducibility and compares well with the grading of lens opacities in photographs. It should prove to be of considerable use in clinical and epidemiological studies of cataract.
TECHNICAL INFORMATION FOR LONG TERM SURVEILLANCE AND MONITORING (2002)

Even after the U.S. Department of Energy’s Office of Environment Management cleanup program has ended, there will be areas that will need to be monitored and maintained for the foreseeable future. This need reflects a fundamental obligation on the part of the DOE and the Federal Government to protect future generations from any residual hazards at these locations. Such a monitoring program must be designed to be cost-effective and to enjoy the highest level of trust of the general public. Thus, not only will the monitoring data need to be gathered efficiently, but also these will need to be presented in a manner that is both easily accessible and understandable to the general public. The program certainly must have a rigorous and visible QA Program with oversight at the national level to insure that the data, as well as the decisions and actions made using these data, are reliable. The experience gained by DOE in this enterprise will be widely applicable, since many other governmental and private sector organizations have similar, if less widely publicized, issues to address. The technical information needed for long term surveillance and monitoring (LTSM) includes monitoring data, QA, data quality objectives, and decision criteria. Proper development, collection, visualization, and management of these technical data are critical to LTSM success. Planning for LTSM involves identification of the technologies needed to make the measurements, development of data collection networks, planning for data transmission and storage, and protocols for data review and validation. Once collected, the data need to be converted into information for the user and integrated with other LTSM systems to provide timely and transparent access to federal managers, stakeholders, and regulators. Finally, record retention policies and data management must be planned.