gebhart/patrepeval huggingface dataset:
Waltershausen and Jena, 1794–1795 (1988)

Abstract Winter journeys became a feature of Friedrich Hölderlin's adult life. About the middle of December 1793 he left home to make his own way outside Swabia. Of that two-day journey he had little to say: day-dreamed of things that were agreeable to him, and worked on the poem ‘Das Schiksaal’. Conflict and opposition were chief constituents of much of the early poetry; they appear now as Fate, as Necessity, against which it is not merely a person's lot but also his privilege to struggle. In Jena, Hölderlin received a further incitement to continual struggle and activity, and that necessary creative restlessness, here still only formulated discursively, he was later able to infuse into the rhythms of his verse. ‘Das Schiksaal’ was a good start to this, positive and optimistic, full of ambition and energy.
A Mobile-IP Based Mobility System for Wireless Metropolitan Area Networks (2005)

The real potential of broadband wireless networks lies with mobility. A hot debate is centered on building metropolitan area networks using WiMAX technology based on the IEEE 802.16 standards. Good mobility management schemes enable it to become the disruptive solution that fulfills the promises of ubiquitous computing with broadband access everywhere that was left unsatisftable with the Wi-Fi and 3G cellular solutions. The wide area coverage and co-existence of multiple wireless access technologies pose a challenge to mobility in the metropolitan network. Complications arise from the hierarchical structure of the network and the seamless handoff requirement to maintain steady streaming media coverage without interruption. It also stems from the lack of cellular type infrastructure to support fast moving users. We study the issues associated with providing mobility in a wireless metropolitan network. We propose a mobility management scheme based on the integration of hierarchical micro-mobility, fast handoff and vertical handoff It is demonstrated that this scheme can perform well under traffic loads. The network is subjected to an application that provides public health informatics services to the metropolitan area. These experimental results can provide suggestion on how to construct the next generation wireless networks.
Mechanical Properties of Suture Materials (1981)

A comprehensive and systematic study of the stress-strain behavior of seven synthetic absorbable and nonabsorbable sutures was conducted. The purpose of the study was to provide detailed mechanical information on suture materials in order to assist surgeons in their selection of adequate sutures for specific surgical applications. The use of a yarn grip, newly designed specifically for fibrous materials, eliminated several difficulties imposed by conventional grips, and resulted in more dependable mechanical properties. A wide range of stress-strain characteristics was observed in the tested sutures. Suture materials of similar nominal properties may behave quite differently in their stress-strain relationship. This was true of sutures of the same chemical nature as well as of different geometric construction, such as Ethilon vs. Nurolon. Larger differences in stress-strain curves were observed after the yield point with yarn grips than with conventional grips. The unique shape of the stress-strain curves, and the associated data derived from them, provide better information in the discrimination between suture materials.
Home help provision to the elderly in France and England. (1987)

Home help is less generous in France than in England. The different systems of administration and operation of the service in the two countries are discussed. The analysis reported used survey data on elderly people over 65 years old living in private households, from samples of 1001 in the London region and 1324 in the Paris region of Ile de France. The data provided information on incapacity, disability for household tasks, support from members of the household, and home help use. The data on disability were used to distinguish in both samples different groups of elderly people needing home help according to alternative criteria. Two measures of efficiency of allocation of home help were used; targetting of the service on those in the need group, and coverage of those in the need group. The ratio of coverage/targetting indicated whether it would be possible to provide for all those in the need group by redistributing existing home help services. In both samples, especially in Paris, the home help service was distributed particularly in favour of lone elderly people with disability for household tasks. For some need groups, targetting seemed equally efficient in Paris as in London, however, the coverage of the parisian system was less comprehensive than in London, reflecting the low overall provision of the service. The implications for policy making and planning for the home help service in France are discussed.
Role of Pulp in Flavor Release and Sensory Perception in Orange Juice (2004)

This work elucidates the role of suspended solids in sensorial perception and flavor release in orange juice. The coarsest pulp (insoluble particles with a diameter of >2 microm) accounted for two major physicochemical effects in orange juice samples: it retained large amounts of aroma compounds, including terpenes and aldehydes, and modified the rheological properties of the juice matrix. These phenomena strongly affected the chemical composition of the vapor phase in the juice samples. On the other hand, orange juice cloud (finest insoluble particles with a diameter of <2 microm) also showed a strong retention effect on ethyl butanoate or hexanal, probably due to the occurrence of molecular interactions with cloud macromolecules. The amount and the size of the suspended solids critically modified not only the texture perception but also the odor and the overall flavor perception, including the "freshly squeezed" and the "artificial flavor" descriptors. The addition of a natural pulp to low-pulp juices increases the fresh orange juice character, a finding that is explained by both physicochemical (fresh pulp contains high amounts of key aroma compounds, including acetaldehyde and mono- and sesquiterpenes) and cognitive effects, mainly due to the tactile properties of the pulp.
PREPARATION AND PROPERTIES OF HIGHMELTING CARBIDE ALLOYS (1963)

An analysis was made of temperature and pressure effects on ZrC and HfC sintering. The results showed that the most dense (2 to 5% porosity) specimens were prepared by hot pressing at 2900 deg C for ZrC and HfC and at 3000 deg C for HfC and TaC. (R.V.J.)
TaoStore: Overcoming Asynchronicity in Oblivious Data Storage (2016)

We consider oblivious storage systems hiding both the contents of the data as well as access patterns from an untrusted cloud provider. We target a scenario where multiple users from a trusted group (e.g., corporate employees) asynchronously access and edit potentially overlapping data sets through a trusted proxy mediating client-cloud communication. The main contribution of our paper is twofold. Foremost, we initiate the first formal study of asynchronicity in oblivious storage systems. We provide security definitions for scenarios where both client requests and network communication are asynchronous (and in fact, even adversarially scheduled). While security issues in ObliviStore (Stefanov and Shi, S&P 2013) have recently been surfaced, our treatment shows that also CURIOUS (Bindschaedler at al., CCS 2015), proposed with the exact goal of preventing these attacks, is insecure under asynchronous scheduling of network communication. Second, we develop and evaluate a new oblivious storage system, called Tree-based Asynchronous Oblivious Store, or TaoStore for short, which we prove secure in asynchronous environments. TaoStore is built on top of a new tree-based ORAM scheme that processes client requests concurrently and asynchronously in a non-blocking fashion. This results in a substantial gain in throughput, simplicity, and flexibility over previous systems.
Computer-Assisted Search Of Large Textual Data Bases (1995)

QA denotes high-speed computer system for searching diverse collections of documents including (but not limited to) technical reference manuals, legal documents, medical documents, news releases, and patents. Incorporates previously available and emerging information-retrieval technology to help user intelligently and rapidly locate information found in large textual data bases. Technology includes provision for inquiries in natural language; statistical ranking of retrieved information; artificial-intelligence implementation of semantics, in which surface level knowledge found in text used to improve ranking of retrieved information; and relevance feedback, in which user's judgements of relevance of some retrieved documents used automatically to modify search for further information.
Fetal loss rate after chorionic villus sampling and subsequent amniocentesis (1990)

Here we review a group of 82 patients who underwent both chorionic villus sampling (CVS) and amniocentesis in the same pregnancy during the period May 1984-May 1988. A fetal loss rate of 2.5% is documented. This is not essentially different from the sum of fetal loss rates following each of the procedures separately (CVS, 1.9%; amniocentesis, 1.0%) established during the same period.
THE COMPARISON OF SAMPLES WITH POSSIBLY UNEQUAL VARIANCES (1939)

The articles published by the Annals of Eugenics (1925–1954) have been made available online as an historical archive intended for scholarly use. The work of eugenicists was often pervaded by prejudice against racial, ethnic and disabled groups. The online publication of this material for scholarly research purposes is not an endorsement of those views nor a promotion of eugenics in any way.
<scp>l</scp>‐Arginine supplementation or arginase inhibition augments reflex cutaneous vasodilatation in aged human skin (2006)

Full expression of reflex cutaneous vasodilatation is dependent on nitric oxide (NO) and vasodilatation is attenuated in healthy older humans. NO bioavailability in aged skin may be decreased by an age-related upregulation of arginase, which reciprocally regulates the NO-synthase (NOS) substrate L-arginine (L-Arg). We hypothesized that increased arginase activity contributes to attenuated vasodilatation in aged skin by limiting L-Arg for NOS-mediated NO synthesis. Five microdialysis fibres were placed in forearm skin of 10 young (Y, 23 +/- 1 years) and 9 older (O, 68 +/- 1 years) human subjects, serving as control (C, Ringer solution), NOS-inhibited (10.0 mM NG-nitro-L-arginine), arginase-inhibited (5.0 mM (S)-(2-boronoethyl)-L-cysteine + 5.0 mM Nomega-hydroxy-nor-L-arginine), L-arg supplemented (L-Arg; 10.0 mM L-arginine) and combined arginase-inhibited + L-Arg sites. After 20 min thermoneutral baseline, cutaneous vasodilatation was induced by passive whole-body heating to increase oral temperature (Tor) by 1.0 degrees C. Red blood cell flux was measured by laser-Doppler flowmetry over each microdialysis site. Cutaneous vascular conductance was calculated (CVC = flux/mean arterial pressure) and normalized to maximal CVC (CVCmax, 28.0 mM sodium nitroprusside + local heating to 43 degrees C). Cutaneous vasodilatation during heating was attenuated in O (Y, 42 +/- 1, versus O, 30 +/- 1%CVCmax, P < 0.001) at control sites. NOS inhibition decreased vasodilatation in both age groups compared to C (Y, 22 +/- 2; O, 18 +/- 2%CVCmax; P < 0.001). Arginase inhibition, L-Arg supplementation, and arginase inhibition + L-Arg supplementation augmented vasodilatation in O (arginase-inhibited, 46 +/- 4; L-Arg, 44 +/- 4; arginase-inhibited + L-arg, 46 +/- 5%CVCmax; P < 0.001 versus C) but not in Y (arginase-inhibited, 46 +/- 4; L-Arg, 38 +/- 4; arginase-inhibited + L-Arg, 44 +/- 4%CVCmax; P > 0.05 versus C). Increasing L-Arg for NO synthesis by either arginase inhibition or direct L-Arg supplementation restores the age-related deficit in reflex cutaneous vasodilatation.
Importance of <i>Coniothyrium minitans</i> in survival of sclerotia of <i>Sclerotinia sclerotiorum</i> in wilted sunflower (1977)

The relationship between Sclerotinia sclerotiorum, causal agent of wilt or basal stem rot of sunflower (Helianthus annuus L.), and its hyperparasite Coniothyrium minitans was investigated in a sunflower field naturally infested with the two organisms. Sclerotia of S. sclerotiorum were collected biweekly from roots and basal stems of wilted plants and analyzed for infection by the hyperparasite. The results showed that C. minitans parasitized and killed the sclerotia produced on the root surface. This hyperparasite continued to parasitize the pathogen inside the root and upwards into the base of the stem, thus infecting the sclerotia produced at these sites. By the end of the growing season, 59%, 76%, and 29% of sclerotia on the root surface, inside the root, and inside the stem, respectively, had been killed by the hyperparasite, while 4%, 9%, and 68% of the sclerotia at these locations were healthy. Death of the rest of the sclerotia was due to organisms other than C. minitans. The data also indicate that C. minitans is more effective in parasitizing sclerotia produced on or inside the root than those produced in the basal stem.
Microtentacles Tip the Balance of Cytoskeletal Forces in Circulating Tumor Cells (2010)

Detection of circulating tumor cells (CTC) is advancing as an effective predictor of patient outcome and therapeutic response. Unfortunately, our knowledge of CTC biology remains limited, and the impact of drug treatments on CTC metastatic potential is currently unclear. Improved CTC imaging in vivo and analysis of free-floating tumor cells now show that cytoskeletal regulation in CTCs contrasts starkly with tumor cells attached to extracellular matrix. In this review, we examine how persistent microtubule stabilization promotes the formation of microtentacles on the surface of detached breast tumor cells and enhances metastatic potential.
<i>ROXY1</i> and <i>ROXY2,</i> two Arabidopsis glutaredoxin genes, are required for anther development (2007)

Glutaredoxins (GRXs) are small oxidoreductases that are involved in various cellular processes and play a crucial role in responses to oxidative stress. Three GRX subgroups exist in plants, and GRXs with active sites of the CPYC and CGFS types are common to pro- and eukaryotes. In contrast, GRXs with the CC type motif have so far only been identified in land plants. Here, we report that the two CC-type GRXs ROXY1 and ROXY2 together control anther development in Arabidopsis thaliana. Single roxy1 and roxy2 mutants are fertile and produce normal anthers. However, roxy1 roxy2 double mutants are sterile and do not produce pollen. Strikingly, abaxial and adaxial anther lobe differentiation are differently affected, with early lobe differentiation being defective in the adaxial lobes, whereas later steps during pollen mother cell differentiation are disrupted in the abaxial lobes. Expression studies show that ROXY1 and ROXY2 are expressed with overlapping patterns during anther development. Lack of ROXY1 and ROXY2 function affects a large number of anther genes at the transcriptional level. Genetic and RT-PCR data imply that ROXY1/2 function downstream of the early-acting anther gene SPOROCYTELESS/NOZZLE and upstream of DYSFUNCTIONAL TAPETUM1, controlling tapetum development. Mutagenesis of a conserved glutathione-binding glycine in the ROXY1 protein indicates that CC-type GRXs need to interact with glutathione to catalyze essential biosynthetic reactions. Analysis of these two novel anther genes indicates that redox regulation, as well as participating in plant stress defense mechanisms, might play a major role in the control of male gametogenesis.
Effect of Ethanol Administration on the Level of Dolichol in Rat Liver Microsomes and Golgi Apparatus (1998)

Data obtained in our laboratory had suggested that acute ethanol administration (6 g/kg body weight) selectively and rapidly affects the intracellular system of protein glycosylation at the level of the Golgi apparatus. Dolichols are important membrane components, and dolichyl phosphate is a glycosyl sugar carrier for N-glycosylation of proteins in endoplasmic reticulum and is considered rate-limiting for this process. In this study, modifications in the concentration and distribution of liver microsomal dolichols after acute ethanol administration were investigated. Between 3 and 24 hr after ethanol administration, the microsomal dolichyl phosphate concentration was significantly lower than in control animals. The highest reduction was observed at 12 hr (-52%). An earlier and more marked reduction of total dolichol was observed in the Golgi apparatus, and, in particular, in the secretory fraction F1 (-70% at 6 hr). Ethanol treatment of isolated hepatocytes led to a significant reduction of the de novo synthesis of both dolichyl phosphate and free dolichol. Moreover, in vitro experiments have demonstrated that pro-oxidant agents lead to a significant decrease of both free dolichol and dolichyl phosphate. Our results suggest that acute ethanol administration induces a marked decrease of dolichols, probably by increasing the degradation and impairing the biosynthetic pathway of these molecules.
Mutant ADA2 in Vasculopathies (2014)

CRT-D between patients with ischemic cardiomyopathy with NYHA class I or class II and patients with nonischemic cardiomyopathy. Hazard ratios were similar in these groups (0.66, 0.65, and 0.57, respectively), which denoted a similar effect size.
Pancreatic islet and stem cell transplantation: new strategies in cell therapy of diabetes mellitus. (2004)

Long-term studies strongly suggest that tight control of blood glucose can prevent the development and retard the progression of chronic complications of type 1 diabetes mellitus. In contrast to conventional insulin treatment, replacement of a patient's islets of Langerhans either by pancreas organ transplantation of by isolated islet transplantation is the only treatment to achieve a constant normoglycemic state and avoiding hypoglycemic episodes, a typical adverse event of multiple daily insulin injections. However, the expense of this benefit is still the need for immunosuppressive treatment of the recipient with all its potential risks. Islet cell transplantation offers the advantage of being performed as a minimally invasive procedure, in which islets can be perfused percutaneously into the liver via the portal vein. As of June 2003, 705 pancreatic islet transplants worldwide have been reported to the International Islet Transplant Registry (ITR) at our Third Medical Department, University of Giessen/Germany. Data analysis shows at 1 year after adult islet transplantation a patient survival rate of 97%, a functioning islet graft in 54% of the cases, whereas insulin independence was meanwhile achieved in 20% of the cases. However, using a novel protocol established by the Edmonton Center/Canada, the insulin independence rates have improved significantly reaching meanwhile a 50-80% level. Finally, the concept of islet cell or stem cell transplantation is most attractive since it offers many perspectives: islet cell availability could become unlimited and islet or stem cells my be transplanted without life-long immunosuppressive treatment of the recipient, just to mention 2 of them.
Why do Most Primary Bladder Neoplasms First Appear Around the Ureteric Orifices? (1993)

The majority of primary bladder neoplasms are known to arise within the mucosa around the ureteric orifices and bladder base. This may be due to the mucosa in this area being more susceptible to carcinogens than other areas of the bladder. Deficiency in the nucleotide salvage pathway enzyme thymidine kinase (TK), and especially its TK1 isozyme, has been shown to predispose cell lines to increased mutagenesis. Total TK and TK1 activities were measured in mucosal samples taken adjacent to the ureteric orifices and dome in 32 normal bladders and both total TK and TK1 were shown to be significantly decreased in the mucosa adjacent to the ureteric orifices. This may explain why primary bladder neoplasms occur more commonly in this site.
Substrate Integrated Waveguide Filter: Basic Design Rules and Fundamental Structure Features (2014)

The electromagnetic (EM) spectrum is becoming more crowded, and it is densely populated with various wireless signals and parasitic interferers in connection with communication and sensing services. Increasingly sophisticated radio-frequency (RF), microwave, and millimeter-wave filters are required to enable the selection and/or rejection of specific frequency channels. This will occur in future generations of the wireless system, such as the current hotly debated fifth-generation communication systems, where the spectral channelization of a heterostructured wide-band signals will be critical in support of a host of coexisting bandwidths or speeds and applications. Bandpass filters have been the most useful and popular types for such applications and are the most difficult to design and develop in practice. Other types of filters such as notch (stopband) and lowpass filters have also been widely used in many systems, and their design is generally perceived less critical with respect to band-pass filters. This article will focus on the presentation and discussion of bandpass filters. Design factors or parameters of filters, such as selectivity, cost, miniaturization, sensitivity to environmental effects (temperature and humidity, for example), and power handling, combined with predefined in-band and out-of-band performance metrics, are critical specifications of the design with respect to the development of RF and microwave front ends. This is indispensable for the efficient utilization of frequency spectrum resources and the cost-effective enhancement of wireless system performances.
Enterobacter Bacteremia in Pediatric Patients (1990)

Enterobacter has emerged as an important human pathogen, particularly in sick, hospitalized patients. Previous reports of nonepidemic enterobacter bacteremia have focused on adult patients. In this report, the epidemiologic factors, clinical characteristics, treatment, and outcome for 33 patients with enterobacter bacteremia in a large children's hospital during a 5-year period are reviewed. The ratio of males to females was 1.2:1. The patients' ages ranged from 2 days to 24 years, and 18 patients were less than 18 months old. Twenty-two cases were nosocomially acquired; six were polymicrobial in nature. Significantly underlying conditions were present in 32 patients. The biliary tract and central venous catheters were the most common sources of bacteremia. Two-thirds of patients had preceding antibiotic therapy. The overall mortality was 24%; mortality attributable to enterobacter bacteremia was 18%. Statistically significant differences in mortality were associated with an age less than 18 months (P = .031) or thrombocytopenia (P = .017); presence of fever was of borderline significance (P = .098). Enterobacter bacteremia is an important cause of morbidity and mortality in pediatric patients.