gebhart/patrepeval huggingface dataset:
Psychiatric Diagnostic Discriminations with Combinations of Quantitative EEG Variables (1984)

The possible psychiatric diagnostic utility of certain quantitative EEG measures was evaluated by further analysis of previously reported data from 242 unmedicated patients and 94 non-patients. Time series of amplitude, frequency and wave symmetry measures for 12-lead EEGs (eyes closed and open) were factor analyzed across leads. Factor scores meeting specified criteria in multivariate analyses were entered into discriminant analyses comparing pairs of the following groups: non-patients, neurotics, personality disorders, overt schizophrenics, latent schizophrenics, major depressives and manics. The following discriminations were obtained with at least 50 per cent sensitivity, and diagnostic confidence rates from 69 to 92 per cent: (a) non-psychotic patients (neuroses, personality disorders) from overt schizophrenics, latent schizophrenics or manics; (b) major depressives from latent schizophrenics or manics; (c) non-patients from schizophrenics (overt and latent), depressives or manics. Most discriminations were replicable in split-half analyses. Possible utility of EEG measures in differential diagnosis is supported.
Coordination of bis(azol-1-yl)methane-based bisphosphines towards Ru<sup>II</sup>, Rh<sup>I</sup>, Pd<sup>II</sup>and Pt<sup>II</sup>: synthesis, structural and catalytic studies (2016)

The coordination chemistry of bisphosphine ligands assembled on the five-membered heterocyclic platform of bis(azol-1-yl)methane viz.: bis(2-diphenylphosphinoimidazol-1-yl)methane (1), bis(5-diphenylphosphinopyrazol-1-yl)methane (2) and bis(5-diphenylphosphino-1,2,4-triazol-1-yl)methane (3) with Ru<sup>II</sup>, Rh<sup>I</sup>, Pd<sup>II</sup> and Pt<sup>II</sup> is described. The bisphosphines 1-3 react with elemental selenium to give the corresponding bis-selenoyl derivatives 4-6. The reactions of 1-3 with transition metal derivatives produce complexes with different coordination modes. Bisphosphine 1 showed a preference for the κ<sup>2</sup>-P,P mode of coordination, whereas bisphosphines 2 and 3, besides the κ<sup>2</sup>-P,P mode also showed a head-to-tail κ<sup>2</sup>-P,N coordination mode resulting in the formation of binuclear complexes [Rh<sub>2</sub>(COD)<sub>2</sub>{(CH<sub>2</sub>(1,2-C<sub>3</sub>H<sub>2</sub>N<sub>2</sub>PPh<sub>2</sub>)<sub>2</sub>)-κ<sup>2</sup>P,N}][BF<sub>4</sub>]<sub>2</sub> (14), [Rh<sub>2</sub>(COD)<sub>2</sub>{(CH<sub>2</sub>(1,2,4-C<sub>2</sub>HN<sub>3</sub>PPh<sub>2</sub>)<sub>2</sub>)-κ<sup>2</sup>P,N}][BF<sub>4</sub>]<sub>2</sub> (15), [Pd<sub>2</sub>(η<sup>3</sup>-C<sub>3</sub>H<sub>5</sub>)<sub>2</sub>{(CH<sub>2</sub>(1,2-C<sub>3</sub>H<sub>2</sub>N<sub>2</sub>PPh<sub>2</sub>)<sub>2</sub>)-κ<sup>2</sup>P,N}][BF<sub>4</sub>]<sub>2</sub> (21) and [Pd<sub>2</sub>(η<sup>3</sup>-C<sub>3</sub>H<sub>5</sub>)<sub>2</sub>{(CH<sub>2</sub>(1,2,4-C<sub>2</sub>HN<sub>3</sub>PPh<sub>2</sub>)<sub>2</sub>)-κ<sup>2</sup>P,N}][BF<sub>4</sub>]<sub>2</sub> (22). Several of these complexes have also been structurally characterized. The in situ generated Rh<sup>I</sup> complex of bisphosphine 1 showed moderate to good selectivity in the hydroformylation of various styrene derivatives.
Tenacibaculum litopenaei sp. nov., isolated from a shrimp mariculture pond (2007)

A yellow-coloured, aerobic, Gram-negative, rod-shaped bacterial strain, designated B-I(T), was isolated from the water of a shrimp (Litopenaeus vannamei) mariculture pond in Taiwan. No species with a validly published name showed 16S rRNA gene sequence similarity of more than 96.5 % to this novel isolate. The highest sequence similarities displayed by strain B-I(T) (93.2-96.1 %) were to members of the genus Tenacibaculum. The phenotypic properties of this organism were consistent with its classification in the genus Tenacibaculum. The novel isolate could be distinguished from all Tenacibaculum species by several phenotypic characteristics. The major fatty acids were iso-C(15 : 0) (22 %), summed feature 3 (C(16 : 1)omega7c and/or iso-C(15 : 0) 2-OH; 21.3 %), iso-C(17 : 0) 3-OH (12.7 %) and iso-C(15 : 1) (8.7 %). The G+C content of the genomic DNA was 35.2 mol%. Hence, genotypic and phenotypic data demonstrate that strain B-I(T) should be classified within a novel species in the genus Tenacibaculum, for which the name Tenacibaculum litopenaei sp. nov. is proposed. The type strain is B-I(T) (=BCRC 17590(T)=LMG 23706(T)).
Morphological and chemical considerations for the epitaxy of metals on semiconductors (1984)

The generally strong chemical interactions between semiconductors and metals introduce additional complexities in the experimental characterization and modelling of epitaxial growth. This article reviews the relevant epitaxial parameters and growth modes in relation to what is known to occur on semiconductors. A salient property of some metals and semimetals is their tendency to form covalent bonds, whose directionality strongly influences the epitaxial relationship between substrate and overgrowth. Both the substrate orientation and, for the binary semiconductors, the stoichiometry of the substrate, strongly influence the epitaxial relationships. Representative examples of the different growth modes are discussed in relation to interfacial bonding, with emphasis on the growth differences between Al, a reactive metal, and Ag, a nonreactive metal on GaAs. The latter part of the article discusses some of the outstanding issues of the epitaxy of metals on semiconductors and possible approaches to their solution.
Correlating Light Absorption with Various Nanostructure Geometries in Vertically Aligned Si Nanowire Arrays (2017)

Exploring the interactions between light and nanostructures contributes greatly to understanding and engineering nanoscale optical phenomena related to device performance. However, this often involves a compromise between uniformity and scalability. Given that optical properties, and especially light absorption, are governed by the geometries of nanostructures, this study investigated the correlation between light absorption and vertically aligned silicon nanowire (v-SiNW) arrays synthesized using KrF stepper lithography. Controlled growth experiments of the v-SiNW arrays indicated that their geometrical parameters strongly influence their corresponding light absorption properties, as confirmed by reflection measurements and finite difference time domain (FDTD) simulations, which showed specific wavelength-dependent absorption. Moreover, the extent of tapering the v-SiNW arrays was modulating to achieve broad absorption of visible light resulting from the gradual change in diameter and to optimize their optical characteristics, based on diameter-dependent nanophotonic resonance, for use in various applications.
Essential role for endothelin ET<sub>B</sub> receptors in fever induced by LPS (<i>E. coli</i>) in rats (1998)

1. The influence of endothelin receptor antagonists on febrile responses to E. coli lipopolysaccharide (LPS), interleukin-1beta (IL-1beta), tumour necrosis factor-alpha (TNF-alpha) and endothelin-1 (ET-1) was assessed in conscious rats. 2. Intravenous (i.v.) LPS (5.0 microg kg(-1)) markedly increased rectal temperature to a peak of 1.30 degrees C over baseline at 2.5 h. Pretreatment with the mixed endothelin ET(A)/ET(B) receptor antagonist bosentan (10 mg kg(-1), i.v.) or the selective endothelin ET(B) receptor antagonist BQ-788 (N-cis-2,6-dimethylpiperidinocarbonyl-L-gamma-methylleucyl-D -1-methoxycarboyl-D-norleucine; 3 pmol, into a lateral cerebral ventricle-i.c.v.) reduced the peak response to LPS to 0.90 and 0.75 degrees C, respectively. The selective endothelin ET(A) receptor antagonist BQ-123 (cyclo[D-Trp-D-Asp-Pro-D-Val-Leu]; 3 pmol, i.c.v.) was ineffective. 3. Increases in temperature caused by IL-1beta (180 fmol, i.c.v.), TNF-alpha (14.4 pmol, i.c.v.) or IL-1beta (150 pmol kg(-1), i.v.) were unaffected by BQ-788 (3 pmol, i.c.v.). 4. Central injection of endothelin-1 (0.1 to 3 fmol, i.c.v.) caused slowly-developing and long-lasting increases in rectal temperature (starting 2 h after administration and peaking at 4-6 h between 0.90 and 1.15 degrees C) which were not clearly dose-dependent. The response to endothelin-1 (1 fmol, i.c.v.) was prevented by BQ-788, but not by BQ-123 (each at 3 pmol, i.c.v.). Intraperitoneal pretreatment with the cyclo-oxygenase inhibitor indomethacin (2 mg kg(-1)), which partially reduced LPS-induced fever, did not modify the hyperthermic response to endothelin-1 (3 fmol, i.c.v.). 5. Therefore, central endothelin(s) participates importantly in the development of LPS-induced fever, via activation of a prostanoid-independent endothelin ET(B) receptor-mediated mechanism possibly not situated downstream from IL-1beta or TNF-alpha in the fever cascade.
Induced Pluripotent Stem Cells for Duchenne Muscular Dystrophy Modeling and Therapy (2018)

Duchenne muscular dystrophy (DMD) is an X-linked recessive disorder, caused by mutation of the <i>DMD</i> gene which encodes the protein dystrophin. This dystrophin defect leads to the progressive degeneration of skeletal and cardiac muscles. Currently, there is no effective therapy for this disorder. However, the technology of cell reprogramming, with subsequent controlled differentiation to skeletal muscle cells or cardiomyocytes, may provide a unique tool for the study, modeling, and treatment of Duchenne muscular dystrophy. In the present review, we describe current methods of induced pluripotent stem cell generation and discuss their implications for the study, modeling, and development of cell-based therapies for Duchenne muscular dystrophy.
Selection of nonprotonated carbon resonances in solid-state nuclear magnetic resonance (1979)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSelection of nonprotonated carbon resonances in solid-state nuclear magnetic resonanceS. J. Opella and M. H. FreyCite this: J. Am. Chem. Soc. 1979, 101, 19, 5854–5856Publication Date (Print):September 1, 1979Publication History Published online1 May 2002Published inissue 1 September 1979https://pubs.acs.org/doi/10.1021/ja00513a079https://doi.org/10.1021/ja00513a079research-articleACS PublicationsRequest reuse permissionsArticle Views909Altmetric-Citations640LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Phase correction by dielectric slabs in sectoral horn antennas (1961)

Beginning with Maxwell's equations, the field components and propagation constants are found inside a plane aperture <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">H</tex> -plane sectoral horn antenna containing two dielectrics. The horn is assumed to be fed from a waveguide containing the dominant <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">TE_{10}</tex> mode. Knowing the phase constants in the two dielectrics makes it possible to calculate the dimensions of a triangular-shaped dielectric slab which, when placed in the horn, can alter the curved phase front and produce an approximation to a uniform-plane phase front at the aperture of the horn. This improved phase front results in an improved far field pattern.
The cost of IUD failure in China. (1993)

By 1988, 71% of the 206 million married Chinese women of reproductive age were using a modern method of contraception. About 60 million women were using IUDs (41%), and 38% relied on tubal ligation, the main methods promoted by the national family planning (FP) program. During several trips to China between May 1990 and October 1991, some serious problems with the use of IUDs in China were discussed with Chinese FP officials. The main IUD produced and used in China is the single-ring, stainless steel IUD, which is made in several sizes (20-23 mm). There are 10 IUD factories in China, most of which manufacture the single ring, the Copper V-200, a uterine-shaped, steel-ring IUD; and several others. The failure and expulsion rates of the single ring are much higher than those of other IUDs. One study, conducted in 1983-84 in 13 provinces, compared 3 IUDs available in China: the single ring, the Copper T-220, and the Copper V-200. The single ring had a 12-month failure (pregnancy) rate of 10.6%, compared with a rate of 1.7% for the Copper T and 2.1% for the Copper V. The 1982 One per Thousand Fertility Survey reported that 34.11% of all abortions obtained by the women surveyed were the result of IUD failure. In abortions obtained by the women surveyed were the result of IUD failure. In a 1987 study, in one county where 32% of the women were using IUDs, 80% of the abortions were obtained after the failure of a contraceptive method, usually the stainless steel IUD. In 1987, there were more than 10 million reported abortions in China that cost the government about $45 million. China's FP program has been criticized for its heavy reliance on abortion. Reducing reliance on the single-ring IUD, by inserting better devices in first-time users and in those women experiencing single-ring failures, may help improve the image of China's FP program.
A single infliximab infusion vs corticosteroids for acute panuveitis attacks in Behcet's disease: a comparative 4-week study (2010)

A single infusion of infliximab should always be considered, even as an adjunct therapy, for the control of acute panuveitis attacks in BD.
Multivariate calibration models using NIR spectroscopy on pulp and paper industrial applications (1996)

A goal for the pulp and paper industry is to get a fast and reliable characterization of raw materials as wood and pulp compositions. One possibility for this is near infrared reflectance (NIR) spectroscopy combined with multivariate analysis. In the first part of this study the possibility to make predictions of mixtures of wood chips from three different wood species (Swedish pine, Swedish spruce and Polish pine) is investigated based on NIR spectroscopy. Mixture design and Partial least squares projections to latent structures (PLS) were used for the multivariate calibration modeling. The calculated model was validated both internally and with an external test set. The result was a PLS model with a Q2 = 0.91 according to cross-validation and good prediction of the test set objects, Q2test set = 0·78. In the second part NIR spectroscopy is used to characterize a series of pulp samples. The pulps were also characterized by seventeen traditionally measured pulp properties. PLS was used for the calibration model and internal as well as external validation were done. The resulting PLS model for the 17 pulp properties gave an overall Q2 = 0·61 according to cross-validation. Predictions of the test set objects show that most of the properties are well described by the model. © 1996 by John Wiley & Sons, Ltd.
ChemInform Abstract: RING‐CLEAVING CYCLOADDITIONS, II. REACTION OF HETEROCUMULENES WITH 5‐ETHOXY‐3‐PHENYLIMINO‐3H‐1,2,4‐DITHIAZOLE (1976)

Abstract Aus Xanthogenamid (I) und dem Senföl (II) in Gegenwart von 1,8‐Diazabicyclo[5.4.0]undecen‐( 7) (DBU) bildet sich der Allophansäureester (III), der zu dem Dithiazol (IV) cyclisiert wird.
The Frontiers of Art (1992)

Wells's distinctive contribution to the art of the short story was to focus attention upon it as a genre distinct from the novel. He rejected the view that it could be defined by fixed standards. In his introduction to The Country of the Blind (1911) he wrote: Each [short story] is intended to be a thing by itself; and if it is not too ungrateful to kindly and enterprising publishers, I would confess I would much prefer to see each printed expensively alone, and left in a little brown-paper cover to lie about a room against the needs of a quite casual curiosity.
Neutron-induced single event upsets in static RAMS observed a 10 km flight attitude (1993)

Observations of 14 neutron-induced single event upsets (SEUs) in static memory devices (SRAMs) at commercial aircraft flight altitudes are described. The observed SEU rate at a 10 km flight altitude based on an exposure of 160 standard 256 kb CMOS SRAMs is 4.8*10/sup -8/ upsets/b/day. In the laboratory, 117 SRAMs of two different brands were irradiated with fast neutrons from a Pu-Be source. A total of 176 SEUs have been observed, including two SEU pairs. The upset rates from the laboratory tests are compared to those found in the airborne SRAMs.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Small molecule ERK5 kinase inhibitors paradoxically activate ERK5 signalling: be careful what you wish for… (2020)

ERK5 is a protein kinase that also contains a nuclear localisation signal and a transcriptional transactivation domain. Inhibition of ERK5 has therapeutic potential in cancer and inflammation and this has prompted the development of ERK5 kinase inhibitors (ERK5i). However, few ERK5i programmes have taken account of the ERK5 transactivation domain. We have recently shown that the binding of small molecule ERK5i to the ERK5 kinase domain stimulates nuclear localisation and paradoxical activation of its transactivation domain. Other kinase inhibitors paradoxically activate their intended kinase target, in some cases leading to severe physiological consequences highlighting the importance of mitigating these effects. Here, we review the assays used to monitor ERK5 activities (kinase and transcriptional) in cells, the challenges faced in development of small molecule inhibitors to the ERK5 pathway, and classify the molecular mechanisms of paradoxical activation of protein kinases by kinase inhibitors.
Improvements in GPS integrity monitoring for non-precision sole means of navigation using hybrid GPS-INS (1997)

International audience
Clinical usefulness of cardiac event recording in dogs and cats examined because of syncope, episodic collapse, or intermittent weakness: 60 cases (1997–1999) (2000)

Results indicate that cardiac event recording had a high diagnostic yield in dogs and cats examined because of unexplained syncope, episodic collapse, or transient weakness and ataxia, regardless of whether animals did or did not have an underlying structural heart disease. Diagnostic yield of cardiac event recording was higher than that reported previously for Holter monitoring.
PERFORMANCE METRICS FOR OBJECT ORIENTED FRONT END COMPUTERS (1999)

Front end computer software in the AGS and RHIC control systems makes extensive use of object oriented programming techniques.A conservative design approach to front end computer architecture has resulted in systems that are not performance limited; however, several interesting performance challenges have been identified.Performance metrics are presented for these situations.Programming techniques which foster high performance object oriented software are discussed.
Representative Graph Neural Network (2020)

Non-local operation is widely explored to model the long-range dependencies. However, the redundant computation in this operation leads to a prohibitive complexity. In this paper, we present a Representative Graph (RepGraph) layer to dynamically sample a few representative features, which dramatically reduces redundancy. Instead of propagating the messages from all positions, our RepGraph layer computes the response of one node merely with a few representative nodes. The locations of representative nodes come from a learned spatial offset matrix. The RepGraph layer is flexible to integrate into many visual architectures and combine with other operations. With the application of semantic segmentation, without any bells and whistles, our RepGraph network can compete or perform favourably against the state-of-the-art methods on three challenging benchmarks: ADE20K, Cityscapes, and PASCAL-Context datasets. In the task of object detection, our RepGraph layer can also improve the performance on the COCO dataset compared to the non-local operation. Code is available at https://git.io/RepGraph.
Partial Discharge Distribution Analysis on Interlace Defects of Cable Joint using K-means Clustering (2007)

To investigate the influence of partial discharge(PD) distribution characteristics due to various defects on the power cable joints interface, we used the K-means clustering method. As the result of PD number(n) distribution analyzing on <TEX>$\Phi-n$</TEX> graph, the phase angle(<TEX>$\Phi$</TEX>) of cluster centroid shifted to <TEX>$0^{\circ}\;and\;180^{\circ}$</TEX> increasing with applying voltage. It was confirmed that the PD quantify(q) and euclidean distance of centroid were increased with applying voltage from the centroid distribution analyzing of <TEX>$\Phi-q$</TEX> plane. The dispersion degree was increased with calculated standard deviation of the <TEX>$\Phi-q$</TEX> cluster centroid. The PD number and mean value on <TEX>$\Phi-q$</TEX> graph were some different by electric field concentration with defect types.
A non-cationic nucleic acid nanogel for the delivery of the CRISPR/Cas9 gene editing tool (2019)

Herein, we report a non-cationic DNA-crosslinked nanogel for intracellular delivery of a Cas9 and single guide RNA (Cas9/sgRNA) complex. A DNA-grafted polycaprolactone brush (DNA-g-PCL) is first loaded with the Cas9/sgRNA complex and then crosslinked by DNA linkers via nucleic acid hybridization to form a nanosized hydrogel, in which the gene editing tools are embedded and protected inside. With compact architecture, the Cas9/sgRNA complex-containing nanogel exhibited excellent physiological stability against nuclease digestion and enhanced cellular uptake efficiency, making the delivery system a promising tool for target genome editing.
The Molecular Chaperone GRP78/BiP in the Development of Chemoresistance: Mechanism and Possible Treatment (2013)

Treatment of several types of cancer such as lung, breast, prostate and pancreas has shown notable progresses in the past decades. However, after an initial response, tumors eventually became resistant to chemotherapy. This phenomenon, known as chemoresistance, accounts for the death of most cancer patients. Several studies in patients refractory to therapy have revealed the upregulation of the molecular chaperone GRP78/BiP both at the RNA and protein expression level. Furthermore GRP78/BiP relocates to the cell membrane in malignant but not in benign cells. In this communication we review studies on the role and the mechanism of action of GRP78/BiP during development of chemoresistance in cancer cells. In addition we discuss the possible role of GRP78 as a biomarker and as a target in cancer therapy.
Investment, Equipment Prices, and Income Tax (1960)

High income-tax rates and an increasing price level, prominent among the economic developments of the last 20 years, have long been strongly criticized in business circles. They are considered major deterrents to investment, acting as brakes on the growth of the economy. Demands for lower tax rates, and for a halt to price escalation (usually called inflation), are constant topics in the business press, in public addresses by high company officials, 1 in presentations for the justification of price or rate increases before regulatory commissions, and in institutional advertising designed for the general public.