gebhart/patrepeval huggingface dataset:
Progress in ferromagnetism research (2006)

Fully Polarised States and Decoherence Ferromagnetism in Undoped Manganites Difference Equations for Correlation Functions and Form Factors of the Eight-Vertex/XYZ Model Basic Properties of Spin Injection and Transport in Ferromagnetic/Polymer Systems Theory of Spintronic Transport in Magnetic Tunnel Junctions Ferromagnetic Phase Transition in Spinor Bose Gases Giant Oscillations of the Density of States and the Conductance in a Ferromagnetic Conductor Coupled to two Superconductors The Effect of Geometry on the Magneto-Transport Properties of Insulating Granular Ferromagnets Many-Particle Effects in Half-Metallic Ferromagnets Phases and Phase Transitions in Spin-Triplet Ferromagnetic Superconductors Field and Stress -Tuneable Microwave Composite Materials Based on Ferromagnetic Wires Phase Diagram and Magnetic Properties of Ferromagnetic Shape Memory Alloys Spin Polarised States in Nuclear Matter with Skyrme Effective Interaction.
Comparison of primary afferent and glutamate excitation of neurons in the mammalian spinal dorsal horn (1988)

The actions of L-glutamate and agonists, agents blocking their membrane receptors and dorsal root afferent volleys, were compared on intracellularly recorded neuronal activity in an in vitro horizontal slice preparation of the hamster spinal dorsal horn. Bath-applied L-glutamate or L-aspartate (less than or equal to 1 mM) rapidly depolarized and excited less than a third of the dorsal horn neurons sampled. Bathing solutions containing low Ca2+ eliminated synaptic transmission in the slices but failed to block the excitatory effects of L-glutamate for the majority of the neurons tested. N-Acetylaspartylglutamate had no effect on dorsal horn neurons at concentrations up to 1 mM. Neurons excited by L-glutamate were most commonly located in the superficial dorsal horn (laminae I and II). Neurons insensitive to L-glutamate were more broadly distributed, with a number being located in laminae III-V. Kynurenic acid, 2-amino-4-phosphonobutyric acid, and 2,3-piperidine dicarboxylic acid selectively antagonized rapid, short-lasting synaptic components of the dorsal cord potentials. Kynurenic acid reversibly antagonized intracellularly recorded L-glutamate-induced excitation, spontaneous synaptic potentials, and fast synaptic potentials evoked by dorsal root volleys. Compounds with strong antagonist actions at the NMDA receptor, 2-amino-5-phosphonovaleric acid and D-alpha-aminoadipic acid, were much less effective in suppressing the effects of L-glutamate or in blocking synaptic potentials. We conclude that a subset of spinal neurons directly excited by dorsal root fibers have excitatory membrane receptors activated by L-glutamate. This conclusion is consistent with the concept that L-glutamate or a substance binding to the receptors it activates is released from the central terminals of some primary afferent fibers and mediates fast synaptic transmission from them to certain spinal neurons in the dorsal horn.
Search for new industrial oils. XIV. Seed oils of labiatae (1967)

Seed of 194 species in 56 genera of Labiatae, representing six of the eight subfamilies, were analyzed for oil and protein and for fatty acid composition of the oil. The oils are diverse and include some that contain up to 70% oleic acid, 79% linoleic acid, or 72% linolenic acid. An allenic function occurs in a third of the samples from the subfamily Stachyoideae and in the one sample analyzed from the Prasioideae. A method for determining the allene was devised. Oils fromTeucrium species containtrans unsaturation in unidentified components. Oils from twoLamium species have both allenic andtrans unsaturation. Two species ofThymus appear to produce hydroxy acids.
The Same Allele of Translation Initiation Factor 4E Mediates Resistance Against Two <i>Potyvirus</i> spp. in <i>Pisum sativum</i> (2007)

Pathogenicity of two sequenced isolates of Bean yellow mosaic virus (BYMV) was established on genotypes of Pisum sativum L. reported to carry resistance genes to BYMV and other potyviruses. Resistance to the white lupin strain of BYMV (BYMV-W) is inherited as a recessive gene named wlv that maps to linkage group VI together with other Potyvirus resistances. One of these, sbm1, confers resistance to strains of Pea seedborne mosaic virus and previously has been identified as a mutant allele of the eukaryotic translation initiation factor 4E gene (eIF4E). Sequence comparison of eIF4E from BYMV-W-susceptible and -resistant P. sativum genotypes revealed a polymorphism correlating with the resistance profile. Expression of eIF4E from susceptible plants in resistant plants facilitated BYMV-W infection in inoculated leaves. When cDNA of BYMV-W was agroinoculated, resistance mediated by the wlv gene frequently was overcome, and virus from these plants had a codon change causing an Arg to His change at position 116 of the predicted viral genome-linked protein (VPg). Accordingly, plants carrying the wlv resistance gene were infected upon inoculation with BYMV-W derived from cDNA with a His codon at position 116 of the VPg coding region. These results suggested that VPg determined pathogenicity on plants carrying the wlv resistance gene and that wlv corresponded to the sbm1 allele of eIF4E.
[Indirect immunofluorescence and complement absorption test characterization of anti-brain antibodies in schizophrenia]. (1981)

The content and tropism of anticerebral antibodies were examined in 20 schizophrenic patients using the indirect immunofluorescence and complement fixation tests. With the aid of the latter the antibodies were revealed in 15 patients, the antibodies to the homologous brain being more frequent in patients with a more severe, continuously progressing schizophrenia, while the antibodies to a heterologous (rat) brain were more often detected in patients with slowly progressing forms of the disease. In 18 patients, the indirect immunofluorescence test showed fixation of immunoglobulins on the nervous tissue components, such as, neurons, myelin, vascular walls. Rather frequently fluorescence of the microglia cells was observed: according to literary data this is not the case with sera of neurological patients. Of attention was a selective fluorescence of the canaliculi observed in examinations of the renal tissue. The data obtained point to a participation of the immunological reactions in the schizophrenia pathogenesis, these reactions involving various morphological and functional systems.
Multitrack Recording of Reduced Bandwidth TV Signals (1967)

The system described here was developed in order to record the pseudorandom scan television signal developed by Deutsch. The objective was to investigate the possibility of recording a 200 kHz video signal on a 1/4 in tape running at 15 in/s. The difficulties which arise in such a task are two-fold: 1) bandwidth limitations of the recorder; and 2) flutter and skew of the recorder. Since a tape recorder at this speed has a bandwidth of about 45 kHz, time-division multiplexing was used to reduce the signal into low-frequency signals. The problem is to reassemble the signals at playback. This is a difficult task since these signals are shifted in time randomly by flutter and skew. Experiments disclose that the skew is linearly distributed across the tape; therefore, by knowing this time shift between two tracks at any instant, the position of the appropriate sample at any other track can be predicted. For skew and flutter compensation purposes two reference signals are recorded on the two outer tracks of the tape. The phaseshift of the reference signals at playback is used as a measure for the skew prediction system for each track. Thus the video signals are sampled at the correct value. In order to reassemble the samples in the correct time sequence, they are stored in analog memory cells. The memory cells are read out with the aid of an oscillator which is in turn synchronized with flutter. The deflection waveforms are also generated synchronous with this oscillator.
Clinical poly(ADP-ribose) polymerase inhibitors for the treatment of cancer. (2007)

Poly(ADP-ribose) polymerase (PARP) is believed to play a critical role in the detection of DNA damage and initiation of DNA repair. Although inhibition of PARP has received increasing attention for therapeutic application in a wide variety of acute and chronic diseases, most of the current clinical data surrounding PARP inhibition is in the field of oncology. At least eight different PARP inhibitors have been, or are expected to be evaluated in the clinical oncology setting in 2007 and 2008. This review summarizes the most recently presented or published data on these therapeutic molecules, and discusses how these drugs may continue to be developed in the future.
Inhibition of erythrocyte sickling in vitro by pyridoxal. (1978)

To test the antisickling activity of pyridoxal, we compared the oxygen affinity and the percent sickling at low PO2 of untreated erythrocytes with values for cells from the same blood sample incubated with pyridoxal, glyceraldehyde, or pyridoxine. Pyridoxal increased oxygen affinity much more than glyceraldehyde. 20 mM pyridoxal and glyceraldehyde had equivalent antisickling activity. At PO2 levels above 20 mm Hg, both agents reduced sickling to less than 2%. In samples examined by electron microscopy, pyridoxal reduced the percent sickled cells and the percent cells that contain hemoglobin S fibers by the same amount (from 74 to 3%). Pyridoxine had no effect on oxygen affinity or sockling. Pyridoxal reacts with intracellular hemoglobin to increase oxygen affinity, which inhibits hemoglobin S polymerization and sickling.
FRET-capable supramolecular polymers based on a BODIPY-bridged pillar[5]arene dimer with BODIPY guests for mimicking the light-harvesting system of natural photosynthesis (2015)

AA/BB-type and A2/B3-type FRET-capable supramolecular polymers based on a BODIPY-bridged pillar[5]arene dimer and two BODIPY derivative guests have been successfully constructed and their application in mimicking the light-harvesting system of natural photosynthesis was studied.
The utility of Pax‐2 as an immunohistochemical marker for renal cell carcinoma in cytopathology (2008)

Pax-2 is a homeogene expressed during kidney development. Its expression in renal cell carcinoma (RCC) has been previously evaluated in histologic samples with a high sensitivity and specificity. Here, we investigated the utility of Pax-2 immunohistochemistry (IHC) for RCC in cytologic material, in comparison with a variety of other neoplasms. Pax-2 IHC was performed on cell block sections of 33 RCCs (14 primary, 19 metastatic) and 35 non-RCC malignancies, including 26 carcinomas, five mesenchymal tumors, one neuroblastoma, two melanomas, and one lymphoma, from fine-needle aspirations and body fluids. The presence or absence of nuclear staining and its intensity and distribution in positive cases were evaluated. Of 33 RCCs, Pax-2 was positive in 20 (61%) and negative in 13 (39%). All staining was nuclear, with an admixture of weakly or strongly staining nuclei. Only an endometrial adenocarcinoma was positive in the non-RCC group. The sensitivity and specificity of Pax-2 IHC for RCC were 61 and 97%, respectively. Pax-2 is a moderately sensitive and highly specific marker for RCC in cytologic material, with a lower sensitivity compared with tissue sections, likely due to a patchy expression pattern, and should be included in the immunohistochemical work-up of malignancies.
Separation of chlorophylls and carotenoids from marine phytoplankton:a new HPLC method using a reversed phase C8 column and pyridine-containing mobile phases (2000)

A high-performance liquid chromatographic (HPLC) method based on a reversed-phase C8 column and pyridine-containing mobile phases was developed for the simultaneous separation of chlorophylls and carotenoids. The method is selective enough to resolve monovinyl (MV) and divinyl (DV) pairs of polar chlorophylls and DV chlorophyll a (chl a ) (the marker pigment for the prokaryote Prochlorococcus marinus) from chl a (the MV analogue). Only the pair DV chl alchl b was not resolved. This resolution capability for chlorophylls was only prev~ously achieved using polymeric C),, columns in combination with ammonium acetate or pyridine-containing mobile phases. The proposed method also allows the separation of taxon-specific carotenoids belonging to 8 algal classes, including some critical pigment pairs for previous HPLC methods using C,, columns. The method employs a binary gradient, so it can be used with both low-pressure and high-pressure mixing instruments. Method transferability was tested using 3 HPLC systems. Only a slight adjustment of gradient profile was required to obtain similar results with HPLC equipment having different dwell volumes. The selectivity of the method towards some recently discovered chlorophyll and carotenoid pigments makes it especially suitable for studying not only fleld samples, but also for re-examining the pigment composition of different algal classes.
The Role of Bilirubin in Diabetes, Metabolic Syndrome, and Cardiovascular Diseases (2012)

Bilirubin belongs to a phylogenetically old superfamily of tetrapyrrolic compounds, which have multiple biological functions. Although for decades bilirubin was believed to be only a waste product of the heme catabolic pathway at best, and a potentially toxic compound at worst; recent data has convincingly demonstrated that mildly elevated serum bilirubin levels are strongly associated with a lower prevalence of oxidative stress-mediated diseases. Indeed, serum bilirubin has been consistently shown to be negatively correlated to cardiovascular diseases (CVD), as well as to CVD-related diseases and risk factors such as arterial hypertension, diabetes mellitus, metabolic syndrome, and obesity. In addition, the clinical data are strongly supported by evidence arising from both in vitro and in vivo experimental studies. This data not only shows the protective effects of bilirubin per se; but additionally, of other products of the heme catabolic pathway such as biliverdin and carbon monoxide, as well as its key enzymes (heme oxygenase and biliverdin reductase); thus, further underlining the biological impacts of this pathway. In this review, detailed information on the experimental and clinical evidence between the heme catabolic pathway and CVD, and those related diseases such as diabetes, metabolic syndrome, and obesity is provided. All of these pathological conditions represent an important threat to human civilization, being the major killers in developed countries, with a steadily increasing prevalence. Thus, it is extremely important to search for novel markers of these diseases, as well as for novel therapeutic modalities to reverse this unfavorable situation. The heme catabolic pathway seems to fulfill the criteria for both diagnostic purposes as well as for potential therapeutical interventions.
Plasma IL-37 Elevated in Patients with Chronic Heart Failure and Predicted Major Adverse Cardiac Events: A 1-Year Follow-Up Study (2017)

A great number of basic and clinical studies have demonstrated that inflammatory cytokines play an important role in the development and progression of chronic heart failure (CHF). However, there is limited information about the role of novel cytokine interleukin-37 (IL-37) in heart failure. We measured plasma IL-37 levels by enzyme-linked immunosorbent assay (ELISA) in 158 patients with chronic heart failure and 30 control subjects. Our results showed that plasma IL-37 levels were significantly elevated in patients with CHF compared with healthy controls (143.73 ± 26.83 pg/ml versus 45.2 ± 11.56 pg/ml, <i>P</i> < 0.001). Furthermore, plasma IL-37 levels were positively correlated with hs-CRP, hs-TnT, and NT-proBNP and negatively correlated with left ventricular ejection function (LVEF). 11 patients died of cardiovascular cause, and 27 HF patients were rehospitalized for worsening HF within 12 months. Multivariate Cox regression analysis showed that plasma IL-37 is an independent predictor of major adverse cardiac events (MACE). Furthermore, CHF patients with >99 pg/ml plasma IL-37 had significantly higher incidences of MACE within 12 months. Our data suggest that plasma IL-37 may play a role in the pathogenesis of CHF and may be a novel predictor of poor prognosis in HF patients.
Left ventricular shape changes induced by aneurysmectomy with endoventricular circular patch plasty reconstruction (1994)

Aneurysmectomy with left ventricular (LV) patch plasty reconstruction for anterior post-infarction LV aneurysm is usually followed by favourable haemodynamic results. The aim of this work was to describe the changes in LV shape induced by the intervention and to correlate them to the pre-operative data and to the surgical results. Twenty-two patients submitted to aneurysmectomy with this technique underwent a haemodynamic study before and 10-15 days after the intervention. Segmental wall motion was studied by the centreline method. LV shape was analysed by calculating the regional curvature of angiographic outlines (RAO 30 degrees projection). Results showed an improvement in LV pump function in 17 patients, which appeared mainly due to increased systolic shortening of the inferior wall. The intervention-induced modifications of LV geometry were characterized by: (1) marked reduction in end-diastolic volume, (2) shift of the angiographic apex counterclockwise, towards the aortic corner, (3) disappearance of the rim with negative curvature corresponding to the infero-apical border of the aneurysm, where the inferior wall resumed a normal outward convexity. No significant difference was found between the pre-operative haemodynamic data of patients who improved after surgery and those who did not. The presence of a rim of negative curvature at the infero-apical border of the aneurysm was the only pre-operative sign with a predictive value for the surgical outcome.
Advances in linear accelerator design for radiotherapy (1984)

The microwave-powered electron linear accelerator, or linac, is becoming the dominant radiotherapy treatment unit. Several technical advances, combined with attention to how patients are most effectively set up and treated, have led to continuing improvements in linac radiotherapy. This review describes: improvements in accelerator structures, widely variable energy linacs , microtrons , beam transport systems, and treatment head design.
The customizable keyboard (1986)

Abstract The need for deviations from the widely accepted QWERTY keyboard layout of usual office typewriters or workstations has been discussed in our twin paper (Gilad et al. 1986). In this paper we examine a related issue: How to customize any keyboard to a given application, cheaply and effectively. We here discuss this issue and establish why such customization is necessary and how modern technology and keyboard design solve half the problem.
Coexpression of invasive markers (uPA, CD44) and multiple drug-resistance proteins (MDR1, MRP2) is correlated with epithelial ovarian cancer progression (2009)

Our results suggest that the overexpression of uPA, CD44 and MRD1 is correlated with EOC progression; both uPA and CD44 are related with drug resistance during EOC metastasis and could be useful therapeutically.
High-performance current conveyor implementation (1984)

Wideband precision current conveyor performance can be obtained by adapting an approach previously developed for current convertors. The proposed circuit implementation of a CCII+ current conveyor significantly exceeds the performance of all previous conveyor circuit formulations and is also more suitable for monolithic fabrication.
Minority carrier capture cross section of the EL2 defect in GaAs (1992)

The EL2 defect in GaAs possesses two levels E1 and E2 located in the gap at 0.75 eV below the conduction band (E1) and 0.5 eV above the valence band (E2) for which only the majority carrier (electron for E1 and hole for E2) capture cross sections have been determined. We present a study in which the occupancy of the E1 level under minority carrier injection, monitored by deep level transient spectroscopy, provides the value of the capture cross section of holes on the E1 level. This enables us to estimate the contribution of the EL2 defect to the minority carrier lifetime in GaAs materials
SÍNDROME DE BURNOUT EM PROFISSIONAIS DE ENFERMAGEM NO SETOR DE URGÊNCIA E EMERGÊNCIA (2019)

INTRODUCAO: O termo burnout foi pela primeira vez utilizado no ano de 1974, sendo mencionado pelo psicologo Herbert J. Freudenberger, que descreveu sua observacao por meio de um quadro contendo jovens trabalhadores de uma clinica de dependentes de substâncias quimicas na cidade de Nova York, Estados Unidos. Sendo a proposta de Maslach a que obteve maior impacto e aceitacao academica, sendo definido como uma sindrome devido ao cansaco emocional, despersonalizacao e baixa realizacao pessoal, que pode ocorrer entre individuos cujo trabalho requer contato com pessoas, principalmente quando essa atividade requer ajuda (medicos, enfermeiros, professores) (MOREIRA, et al, 2009). OBJETIVOS: Avaliar os fatores estressores que influenciam no surgimento da Sindrome de Burnout e sua repercussao em profissionais de enfermagem que atuam no setor de urgencia e emergencia. METODOLOGIA: Para alcancar o proposito do projeto, foi optado pelo uso do metodo da revisao integrativa, pois viabiliza a sintese dos resultados de diversos estudos possibilitando conclusoes gerais do tema. A pesquisa foi baseada a partir dos bancos de dados eletronicos LILACS (Literatura Latino-Americano e Caribe em Ciencias da Saude) e Scielo (Scientific Eletronic Library Online), com os seguintes descritores que foram obtidos no Decs (Descritores em Ciencias da Saude) os quais sao: Esgotamento Profissional, Profissionais de Enfermagem, Pessoal de Saude, Emergencias.  RESULTADOS ESPERADOS : Este projeto contribuira para os estudos ja existentes sobre a Sindrome de Burnout, dando enfase nos fatores que influenciam para o desenvolvimento da mesma mostrando como ela impacta nos profissionais de enfermagem que atuam no setor de urgencia e emergencia.