gebhart/patrepeval huggingface dataset:
A radial velocity spectrometer for the Automated Planet Finder Telescope at Lick Observatory (2010)

The Ken and Gloria Levy Spectrometer is being constructed at the Instrument Development Laboratory (Technical Facilities) of UCO/ Lick Observatory for use on the 2.4 meter Automated Planet Finder Telescope at Mt. Hamilton. The mechanical design of the instrument has been optimized for precision Doppler measurements. A key component of the design is the space-frame structure that contains passive thermal compensation. Determinate hexapod structures are used to mount the collimator, prism, and echelle grating. In this paper we describe the instrument mechanical design and some features that will help it detect rocky planets in the habitable zone.
ChemInform Abstract: The η<sup>6</sup>,η<sup>1</sup>‐Coordination of Beryllium Atoms in the Graphite Analogue BeB<sub>2</sub>C<sub>2</sub>. (2008)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Phosphorylation of the regulatory subunit of smooth muscle protein phosphatase 1M at Thr850 induces its dissociation from myosin (2002)

Rho kinase is known to control smooth muscle contractility by phosphorylating the 110 kDa myosin-targetting subunit (MYPT1) of the myosin-associated form of protein phosphatase 1 (PP1M). Phosphorylation of MYPT1 at Thr695 has previously been reported to inhibit the catalytic activity of PP1. Here, we show that the phosphorylation of Thr850 by Rho kinase dissociates PP1M from myosin, providing a second mechanism by which myosin phosphatase activity is inhibited.
Dhydro: a generic environment developed to edit and access multilingual terminological data on the Internet (2000)

This paper is intended to provide a description of the functionalities of the Dhydro1 platform for the editing and consultation of multilingual terminological data bases. Initially, this platform was developed to allow the updating and computerized accessibility of the International Hydrographic Dictionary (IHD). Published by the International Hydrographic Bureau (IHB), this dictionary initially consisted of three monolingual volumes (English, French, and Spanish) containing hydrography-related terminology. These dictionaries were maintained by editors specialized in each of the languages. However, the geographical distance between them adversely affected the actual development of the dictionaries, whereas the printed format restricted the dissemination of terminology vital to the maritime community. The Dhydro project has two major objectives: • To provide the editors with the necessary communication tools to enable them effectively to interact with each other, to edit terminological data, to ensure quick access to the data base and to publish it in various formats (bilingual or trilingual glossaries, monolingual dictionaries, etc.). • To ensure the widest possible access to the terminological data base, with the IHB having agreed to publicize the data resulting from the project2. While this clearly identified the thematic field, we also sought to ensure that the tools used would be independent of, on the one hand, any particular area of specialization, and, on the 1 DHYDRO
Positioning accuracy of a new image-guided radiotherapy system (2011)

The isocenter alignment among the coordinate systems was performed with high accuracy. Furthermore, the automatic image fusion function achieved sufficient patient positioning accuracy and precision for image-guided radiotherapy.
Diffuse Large B-Cell Lymphoma of the Prostate (2014)

In this article, we review prostatic lymphomas and discuss the differential diagnosis of high-grade malignant neoplasms of the prostate. We illustrate this with a case of a 46-year-old man seen with lower urinary tract obstruction who had diffuse involvement by a high-grade malignancy on prostate biopsy. Morphologic evaluation and immunohistochemistry were consistent with diffuse large B-cell lymphoma of the prostate. Workup with positron emission tomography-computed tomography demonstrated intensely hypermetabolic lymph nodes in the mediastinum, as well as widespread osseous involvement and involvement of the pancreatic tail, prostate, and urinary bladder, suggesting secondary prostatic involvement by a nodal lymphoma. Lymphomas of the prostate are uncommon in surgical pathology practice and usually represent secondary involvement from leukemia/lymphoma at a more typical site. Chronic lymphocytic leukemia/small lymphocytic lymphoma is the most common subtype.
<title>Objective and subjective assessment of a new diffractive trifocal contact lens</title> (1997)

We tested the objective and subjective performance of the Holo-Or rigid gas permeable multifocal contact lens, a new trifocal diffractive contact lens. Eleven experienced and two non-experienced rigid gas permeable contact lens wearers participated in the study. Eleven patients were presbyopic (age 40 - 57) and two aphakic (age 12 and 14). All patients were tested both with their best spectacle correction for distance and near and the trifocal diffractive contact lenses. The follow up period was 3 - 8 months. Subjective opinion was also assessed. Statistical analysis was performed using Student's T-test. We did not find any significant difference in visual acuity measured at 6 m, 80 cm and 40 cm, between best spectacle correction and Holo-Or diffractive contact lenses. Depth of focus improved to a statistically significant extent when using trifocal contact lenses. A small reduction in contrast sensitivity was observed when the patients used the multifocal contact lenses. Overall satisfaction and comfort was good to excellent in ten of the thirteen patients. Two other patients who used a bifocal model of the same contact lens design showed similar results. Holo-Or trifocal diffractive contact lenses are a satisfactory means of optical correction for patients with presbyopia or accommodative problems.
Preparation of Vitreous Materials in the Form of Well-Defined Hollow Cylinders (1969)

Method for preparation of vitreous materials in hollow cylindrical form, considering chemical homogeneity, porosity and geometrical shape
[Asthma and infection: risk or prevention?]. (1998)

Upper respiratory tract infections and wheezing illnesses occur frequently in early childhood. Most viral infections associated with wheeze in infancy are attributable to respiratory syncitial virus, whereas in older children rhinovirus, influenza and parainfluenza virus prevail. The detection rate of viruses has increased since PCR techniques have been used. A British study for example showed that in 80% of episodes in asthmatic children aged 9-11 years viruses could be detected in nasal aspirates which had been taken within 4 days of the wheezing attack. In most cases rhinovirus was identified. Two major hypotheses have been proposed to explain the association between respiratory tract infections and subsequent respiratory abnormalities. One hypothesis states that viral infections early in life damage the growing lung or alter host immune regulation. The second hypothesis holds that respiratory infections are more severe in infants and children with some underlying predisposition. These notions await further clarification. Early childhood bacterial and viral infections may, however, also be associated with a reduced risk of developing atopic sensitization or allergic conditions, as the results of several recent studies suggest.
Piezo-Phototronic Effect on Electroluminescence Properties of <i>p</i>-Type GaN Thin Films (2012)

We present that the electroluminescence (EL) properties of Mg-doped p-type GaN thin films can be tuned by the piezo-phototronic effect via adjusting the minority carrier injection efficiency at the metal-semiconductor (M-S) interface by strain induced polarization charges. The device is a metal-semiconductor-metal structure of indium tin oxide (ITO)-GaN-ITO. Under different straining conditions, the changing trend of the transport properties of GaN films can be divided into two types, corresponding to the different c-axis orientations of the films. An extreme value was observed for the integral EL intensity under certain applied strain due to the adjusted minority carrier injection efficiency by piezoelectric charges introduced at the M-S interface. The external quantum efficiency of the blue EL at 430 nm was changed by 5.84% under different straining conditions, which is 1 order of magnitude larger than the change of the green peak at 540 nm. The results indicate that the piezo-phototronic effect has a larger impact on the shallow acceptor states related EL process than on the one related to the deep acceptor states in p-type GaN films. This study has great significance on the practical applications of GaN in optoelectronic devices under a working environment where mechanical deformation is unavoidable such as for flexible/printable light emitting diodes.
ChemInform Abstract: Novel Inhibitors of the Prenylated Protein Methyltransferase Reveal Distinctive Structural Requirements. (1997)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Confinement effects of oxide overlayers on the stress and yield behavior of Al alloys (1993)

The effect of oxide confinement on the stress and yield behavior of AlCuSi and AlCu films on oxidized Si substrates have been measured by bending beam techniques and examined using a film strength model. Our results reveal that the oxide thickness, alloy thickness, and metal grain size play a role in determining the plastic deformation behavior of the metal films above approximately 200 degree(s)C. The stress analysis of multilayers for bending beam measurements has been extended to include plastic deformation, making it possible to directly determine the effects of the oxide overlayer on the stress and yield behavior of the Al alloy film. Complementary transmission electron microscopy (TEM) studies of the Al alloy reveal that differences in the grain size with and without a SiO<SUB>2</SUB> passivation layer are central to determining whether an increase in film strength due to the passivation oxide will be observable. The overall experimental results, particularly the contrasting effects observed for AlCuSi and AlCu films, can be satisfactorily accounted for by a film strength model which takes into account the roles of film thickness, oxide thickness, and grain size in controlling the yield strength.
Efficacy of chemopreventive agents for growth inhibition of Apc [+/-] 1638NCOL colonic epithelial cells (2002)

Germline mutations of the Apc tumor suppressor gene result in increased risk for gastrointestinal carcinogenesis. The Apc1638N [+/-] mouse exhibits accelerated gastrointestinal carcinogenesis that is modifiable by select pharmacological and dietary agents. Experiments in the present study were conducted on a subculturable epithelial 1638NCOL cell line established from histologically normal colon of Apc1638N [+/-] mouse to examine the effects of selected chemopreventive agents that differ in their mechanism of action. Extent of growth arrest, number of cell population doublings, cell cycle progression and aneuploid G0/G1: S + G2/M ratio represented the quantitative endpoints for the susceptibility and efficacy of chemopreventive agents. Treatment of exponentially growing 1638NCOL cells with maximum cytostatic dose of 9cisRA, DFMO or SUL (100 microM) produced a 60-70% growth arrest, that with TAM and AMF (10 microM) produced a 20-40% growth arrest, while that with OLT (100 microM) produced a 25% growth arrest. This response was associated with corresponding decrease in the number of cell population doubling. 9cisRA, SUL or AMF increased the aneuploid G0/G1: S + G2/M ratio by inducing G1 checkpoint arrest, while DFMO, TAM and OLT decreased the ratio by inducing G2 checkpoint arrest. Thus, cell cycle phase-dependent susceptibility of the Apc [+/-] 1638NCOL cell line to mechanistically distinct chemopreventive agents validates a novel colon epithelial cell culture model for mechanistic, preventive or therapeutic studies on Apc regulated colon carcinogenesis.
Effects of capsaicin on the development of gastric mucosal damage by different necrotizing agents and of gastric cytoprotection by PGI2 atropine and cimetidine on rats. (1984)

Capsaicin desensitization was used as a tool to reveal the role of neurogenic inflammation in the gastric mucosal lesions induced by intragastric application of four different noxious chemical agents (96% ethanol, 0.6 M HCl, 0.2 M NaOH, 25% NaCl). In capsaicin desensitized rats the number of lesions did not differ from that of the controls one hour after the application. There was, however, a significant reduction in the severity of the mucosal damage. These findings provide the first evidence for the participation of neurogenic inflammation in the gastric mucosal damage induced by aggressive chemicals. Gastrocytoprotection induced by prostacyclin (PGI2, 5 micrograms/kg), atropine (25 micrograms/kg) or cimetidine (2.5 mg/kg) was not inhibited in capsaicin desensitized rats. The number of lesions was not altered, while the severity of damage was more effectively reduced in the desensitized group. These findings indicate that the cytoprotective effect of these drugs is not mediated through capsaicin-sensitive sensory-efferent local tissue reactions.
Cryogenic Ion Spectroscopy of Peptides and Glycans (2017)

Understanding the structure of biomolecules, which are directly related to physiological processes that take place in the human body, has always generated a large interest in the scientific community. In this thesis we focus our attention on two of these classes of biomolecules: peptides and glycans. In the first part of this work we investigate how the structure of helical peptides in the gas-phase is modified when one increases the number of amino acids in the sequence. Moreover, we analyze the role played by a mobile charge in the formation of the helical motif in the gas-phase. To achieve these goals, we make use of a home-built tandem mass spectrometer, and a pump-probe laser spectroscopic scheme. The combination of infrared and ultraviolet light together with cryogenic temperatures allows one to collect high-resolution conformer-specific spectra of gas-phase peptides. By comparing the experimental results obtained with density functional theory calculations, we show that the synergy between theory and experiment is key to provide accurate structural characterization of the investigated peptides. The mobile charge, in fact, induces unconventional backbone conformations, which cannot be predicted a priori by performing experiments alone. In the second part of this thesis we present a novel technique to identify and characterize glycans in the gas-phase that exploits a database approach. Due to their structural heterogeneity, glycans pose a problem for the currently available mass- and mobility-spectrometry techniques. In the work herein we show that we can easily identify glycan structural isomers, by adding a spectroscopic dimension to mass and mobility measurements. Cryogenic vibrational messenger spectroscopy, in fact, allows us to unambiguously identify disaccharides and pentasaccharides isomers due to the high-resolution provided by this method. Moreover, we can perform our experiments in a broad range of temperatures, going from liquid helium to liquid nitrogen. This shows the potential of our technique in becoming a more accessible analytical tool for glycan identification.
Introduction to the Special Issue on the 2019 International Solid-State Circuits Conference (2019)

Two papers were selected from the digital hardware related sessions of ISSCC 2019. Both papers propose energy-efficient architectures and circuits for accelerating deep neural networks inference and training. The first paper, by Kim <italic xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">et al.</i> , demonstrates a mobile processor that can perform reinforcement learning at high energy efficiency (2.1 TFLOPS/W) via a novel experience compression scheme. The second paper, by Lee <italic xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">et al.</i> , proposes another energy-efficient processor for learning. It can flexibly support 8-bit floating point (FP8) to 16-bit floating point (FP16) and achieves 25.3 TFLOPS/W.
<i>J</i>‐IMPEACH‐MBC: a new concatenated NMR experiment for <i>F</i><sub>1</sub> scalable, <i>J</i>‐resolved HMBC (2001)

Abstract A new and improved NMR experiment for F 1 scalable, J ‐Resolved HMBC is presented. This experiment, called J ‐IMPEACH‐MBC, utilizes a minimum number of 180° pulses to preserve maximum signal‐to‐noise ratio and provides a variable scaling factor ( N ) that can be used to scale the heteronuclear couplings in F 1 . It should prove to be useful for the determination of relative stereochemistry and other structural problems. In addition, a description of the advantages of the J ‐IMPEACH‐MBC compared with the J ‐Resolved HMBC‐2 is presented. The method is exemplified with strychnine. Copyright © 2001 John Wiley & Sons, Ltd.
A j-lanes tree hashing mode and j-lanes SHA-256. (2012)

Abstract. j-lanes hashing is a tree mode that splits an input message to j slices, computes j independent digests of each slice, and outputs the hash value of their concatenation. We demonstrate the performance advantage of j-lanes hashing on SIMD architectures, by coding a 4-lanes-SHA-256 implementation and measuring its performance on the latest 3 rd Generation Intel ® Core ™. For message ranging 2KB to 132KB in length, the 4-lanes SHA-256 is between 1.5 to 1.97 times faster than the fastest publicly available implementation (that we are aware of), and between ~2 to ~2.5 times faster than OpenSSL 1.0.1c. For long messages, there is no significant performance difference between different choices of j. We show that the 4-lanes SHA-256 is faster than the two SHA3 finalists (BLAKE and Keccak) that have a published tree mode implementation. We explain why j-lanes hashing will be even faster on the future AVX2 architecture with 256 bits registers. This suggests that standardizing a tree mode for hash functions (SHA-256 in particular) would deliver significant performance benefits for a multitude of algorithms and usages.
The effect of a stem on the tibial component of knee arthroplasty. A roentgen stereophotogrammetric study of uncemented tibial components in the Freeman-Samuelson knee arthroplasty (1990)

We studied the effect of a metal tray with an intramedullary stem on the micromotion of the tibial component in total knee arthroplasty. Of 32 uncemented Freeman-Samuelson knee arthroplasties performed in London and Gothenburg, nine had a metal backing and stem added to the tibial component. Micromotion of the tibial components, expressed as migration and inducible displacement, was analysed using roentgen stereophotogrammetric analysis up to two years follow-up. The addition of a metal back and a 110 mm stem to the standard polyethylene component significantly reduced both migration over two years and inducible displacement.
HST Imaging of Atmospheric Phenomena Created by the Impact of Comet Shoemaker-Levy 9 (1995)

Hubble Space Telescope (HST) images reveal major atmospheric changes created by the collision of comet Shoemaker-Levy 9 with Jupiter. Plumes rose to 3000 kilometers with ejection velocities on the order of 10 kilometers second-1; some plumes were visible in the shadow of Jupiter before rising into sunlight. During some impacts, the incoming bolide may have been detected. Impact times were on average about 8 minutes later than predicted. Atmospheric waves were seen with a wave front speed of 454 +/- 20 meters second-1. The HST images reveal impact site evolution and record the overall change in Jupiter's appearance as a result of the bombardment.
L'aide apportée par les collectivités locales aux grévistes : une compétence incertaine, des conséquences contestables (1991)

International audience
<title>3D kinematics of the tarsal joints from magnetic resonance images</title> (2001)

We have developed a method for analyzing motion at skeletal joints based on the 3D reconstruction of magnetic resonance (MR) image data. Since the information about each voxel in MR images includes its location in the scanner, it follows that information is available for each organ whose 3D surface is computed from a series of MR slices. In addition, there is information on the shape and orientation of each organ, and the contact areas of adjacent bones. By collecting image data in different positions we can calculate the motion of the individual bones. We have used this method to study human foot bones, in order to understand normal and abnormal foot function. It has been used to evaluate patients with tarsal coalitions, various forms of pes planus, ankle sprains, and several other conditions. A newly described feature of this system is the ability to visualize the contact area at a joint, as determined by the region of minimum distance. The display of contact area helps understand abnormal joint function. Also, the use of 3D imaging reveals motions in joints which cannot otherwise be visualized, such as the subtalar joint, for more accurate diagnosis of joint injury.
Sleep-Predominant Lowering of Ambulatory Blood Pressure by Bedtime Inhalation of a Novel Muscarinic M3 Receptor Antagonist: A New “Bronchoantihypertensive” Strategy Targeting the Lung in Hypertension with Chronic Obstructive Pulmonary Disease (2008)

Bedtime inhalation of a novel muscarinic M3 receptor antagonist markedly lowered ambulatory blood pressure (ABP), predominantly during sleep, in a chronic obstructive pulmonary disease (COPD) patient with masked nocturnal hypertension. This is the first case demonstrating that a bronchodilator significantly lowered ABP in a COPD patient with hypertension. This case suggests that bronchodilator therapy may have potential as a new antihypertensive strategy targeting the lung in hypertensive patients with impaired lung function. This "bronchoantihypertensive" therapy seems to be more effective for reducing sleep blood pressure in hypertensive patients with COPD and sleep hypoventilatory/hypoxemic syndromes.
Large format and high sensitivity VO x μ-bolometer detectors at SCD (2007)

SCD has established an uncooled detector product line based on the high-end VO<sub>x</sub> μ-bolometer technology. The first PFA launched was <i>BIRD384</i>, a 384x288 (or 320x240) configurable format with 25μm pitch. Typical NETD values for these FPAs are below 50mK with an F/1 aperture and 60 Hz frame rate. The product exhibits superior image uniformity, stability and reduced power consumption, making it most suitable for a broad range of "high-end" military and commercial applications. In this paper we report on our progress in development of new products in accordance with SCD's uncooled products roadmap: 1. A "sensitive" version of <i>BIRD384</i> with an improved NETD of ~ 30mK @ F/1, 60Hz frame rate. This performance is achieved by optimizing concurrently the membrane structure, pixel architecture and ROIC electronics. 2. An improved version of <i>BIRD384</i> ROIC that supports 100/120Hz frame rate and high dynamic range ("Fire Man" option). 3. First data of the <i>BIRD640</i> - a 640x480 array with 25μm pitch and NETD ≤ 50mK @ F/1, 60Hz frame rate.