gebhart/patrepeval huggingface dataset:
Deuteron NMR study of benzene-d6 in a liquid-crystalline polysiloxane (1991)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTDeuteron NMR study of benzene-d6 in a liquid-crystalline polysiloxaneMichael Schulz, Arthur Van der Est, Ernst Roessler, Gerhard Kossmehl, and Hans Martin ViethCite this: Macromolecules 1991, 24, 18, 5040–5045Publication Date (Print):September 1, 1991Publication History Published online1 May 2002Published inissue 1 September 1991https://pubs.acs.org/doi/10.1021/ma00018a009https://doi.org/10.1021/ma00018a009research-articleACS PublicationsRequest reuse permissionsArticle Views104Altmetric-Citations16LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Higher Median Levels of Free β-hCG and PAPP-A in the First Trimester of Pregnancy in a Chinese Ethnic Group (2005)

Ethnic Chinese have a significantly higher maternal serum level of free beta-hCG and PAPP-A in the first trimester, which could not be explained by differences in maternal weight. Adjustment for ethnicity may be necessary for these biochemical markers in a first trimester screening program.
Energy implications of solid-state lighting technology (2008)

The efficient yet highly controllable generation of light can be accomplished by light-emitting diodes that can have a 20 times greater efficiency than incandescent light sources. Implications on energy, environment, and finances will be discussed.
Glioma Cell Migration Dynamics in Brain Tissue Assessed by Multimodal Optical Imaging (2019)

Glioblastoma is a primary malignant brain tumor characterized by highly infiltrative glioma cells. Vasculature and white matter tracts are considered to be the preferred and fastest routes for glioma invasion through brain tissue. In this study, we systematically quantified the routes and motility of the U251 human glioblastoma cell line in mouse brain slices by multimodal imaging. Specifically, we used polarization-sensitive optical coherence tomography to delineate nerve fiber tracts while confocal fluorescence microscopy was used to image cell migration and brain vasculature. Somewhat surprisingly, we found that in mouse brain slices, U251 glioma cells do not follow white matter tracts but rather preferentially migrate along vasculature in both gray and white matter. In addition, U251 cell motility is ∼2-fold higher in gray matter than in white matter (91 vs. 43 μm<sup>2</sup>/h), with a substantial fraction (44%) of cells in both regions invading without close association with vasculature. Interestingly, within both regions, the rates of migration for the perivascular and televascular routes of invasion were indistinguishable. Furthermore, by imaging of local vasculature deformation dynamics during cell migration, we found that U251 cells are capable of exerting traction forces that locally pull on their environment, suggesting the applicability of a "motor-clutch"-based model for migration in vivo. Overall, by quantitatively analyzing the migration dynamics along the diverse pathways followed by invading U251 glioma cells as observed by our multimodal imaging approach, our studies suggest that effective antiinvasive strategies will need to simultaneously limit parallel routes of both perivascular and televascular invasion through both gray and white matter.
EXPECTED IMPACT OF HANFORD PROCESSING ORGANICS OF PLUTONIUM DURING TANK WASTE SLUDGE RETRIEVAL (2004)

This document evaluates the potential for extracting plutonium from Hanford waste tanks into residual organic solvents and how this process may have an impact on criticality specifications during the retrieval of wastes. The two controlling factors for concentrating plutonium are the solubility of the plutonium in the wastes and the extraction efficiency of the potential organic extractants that may be found in these wastes. Residual Hanford tank sludges contain plutonium in solid forms that are expected to be primarily insoluble Pu(IV) hydroxides. Evaluation of thermodynamic Pourbaix diagrams, documentation on solubility studies of various components in waste tank matrices, and actual analysis of plutonium in tank supernates all indicate that the solubility of Pu in the alkaline waste is on the order of 10{sup -6} M. Based on an upper limit plutonium solubility of 10{sup -5} M in high pH and a conservative distribution coefficient for organic extractants of <0.01 (the E{sub a}{sup 0} for plutonium in 30% TBP at 0.07 M HNO{sub 3}), the estimated concentration for plutonium in the organic phase would be <1 x 10{sup -7} M. This is well below the process control criteria. A significant increase in plutonium solubility or the E{sub a}{sup o} would have to occur to raise this concentration to the 0.01 M concern level for organics. Measured tank chemical component values, expected operating conditions, and the characteristics of the expected chemistry and extraction mechanisms indicate that concentration of plutonium from Hanford tank residual sludges to associated process organic extractants is significantly below levels of concern.
Conformation of cyclic peptides. VII. Cyclic hexapeptides containing the D-Phe-L-Pro sequence (1973)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTConformation of cyclic peptides. VII. Cyclic hexapeptides containing the D-Phe-L-Pro sequenceKenneth D. Kopple, Anita. Go, Thomas J. Schamper, and Craig S. WilcoxCite this: J. Am. Chem. Soc. 1973, 95, 18, 6090–6096Publication Date (Print):September 1, 1973Publication History Published online1 May 2002Published inissue 1 September 1973https://pubs.acs.org/doi/10.1021/ja00799a042https://doi.org/10.1021/ja00799a042research-articleACS PublicationsRequest reuse permissionsArticle Views92Altmetric-Citations31LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
The Linear Regression Model With Autocorrelated Errors: Just Say No To Error Autocorrelation (2002)

This paper focuses on the practice of serial correlation correcting of the Linear Regression Model (LRM) by modeling the error. Simple Monte Carlo experiments are used to demonstrate the following points regarding this practice. First, the common factor restrictions implicitly imposed on the temporal structure of yt and xt appear to be completely unreasonable for any real world application. Second, when one compares the Autocorrelation-Corrected LRM (ACLRM) model estimates with estimates from the (unrestricted) Dynamic Linear Regression Model (DLRM) encompassing the ACLRM there is no significant gain in efficiency! Third, as expected, when the common factor restrictions do not hold the LRM model gives poor estimates of the true parameters and estimation of the ACLRM simply gives rise to different misleading results! On the other hand, estimates from the DLRM and the corresponding VAR model are very reliable. Fourth, the power of the usual Durbin Watson test (DW) of autocorrelation is much higher when the common factor restrictions do hold than when they do not. But, a more general test of autocorrelation is shown to perform almost as well as the DW when the common factor restrictions do hold and significantly better than the DW when the restrictions do not hold. Fifth, we demonstrate how simple it is to, at least, test the common factor restrictions imposed and we illustrate how powerful this test can be.
Indicaciones terapéuticas en odontología de los nuevos antibióticos macrólidos en acción prolongada (2000)

Generalidades: En el tratamiento de las infecciones orales, los medicos han utilizado la eritromicina, un antibiotico de la familia de los macrolidos, como alternativa para el manejo de los pacientes con reacciones alergicas demostradas a la penicilina. En este articulo, el autor informa acerca de su valoracion sobre la farmacologia de la eritromicina y de otros antibioticos macrolidos mas modernos, asi como de sus indicaciones en la prevencion de la endocarditis bacteriana y de su posible utilizacion en las infecciones orales y dentales. 
Tipos de estudios revisados: El autor reviso la bibliografia mas reciente sobre farmacologia clinica, haciendo un especial hincapie en los articulos sobre la eficacia de estos antibioticos en el tratamiento de las infecciones odontologicas. 
Resultados: Los antibioticos analogos a la eritromicina comercializados actualmente en Estados Unidos son azitromicina, claritromicina y diritromicina. En comparacion con la eritromicina, los tres antibioticos presentan mayor duracion de accion, mejor estabilidad en medio acido y mejor distribucion en los tejidos. Asimismo, y en comparacion con la eritromicina, en estos tres nuevos macrolidos se ha informado tambien una incidencia mas baja de sintomas gastrointestinales y de colicos abdominales. La azitromicina y la diritromicina no parecen competir por las mismas enzimas de metabolizacion hepatica que la eritromicina, por lo que no se asocian a interacciones farmacologicas con este antibiotico. 
Conclusiones e implicaciones clinicas: En comparacion con la eritromicina, los modernos macrolidos ofrecen la ventaja de presentar una menor incidencia de efectos secundarios gastrointestinales, asi como unas pautas de dosificacion de solo una o dos veces al dia. No obstante, y comparados con la eritromicina, su utilizacion habitual se ve limitada por el coste extraordinariamente elevado de estos nuevos antibioticos.
n-type conduction in a-Ge<sub>20</sub>Bi<sub>4</sub>Se<sub>76</sub>thin films (1988)

Abstract Amorphous thin 6lms of Ge20Bi4Se76 exhibiting n-type conduction are reported for the first time. As compared to a-Ge20Se80 films, the modified films (a-Ge20Bi4Se76) show an increase in room-temperature electrical conductivity by several orders of magnitude, a transition from p-to n-type conduction, a decrease in the optical gap from 1.9 to 1.5 eV and a drastic fall in the electrical activation energy from 0.85 to 0.17eV. The correlation of the electrical and optical data suggests the existence of localized states at the conduction band edge arising from the incorporation of bismuth. The decrease of the activation energy for electrical conduction is much larger than the decrease of one-half the optical gap. This indicates unpinning of the Fermi level with a shift towards the conduction band edge.
In Vitro and Ex Vivo Neurochemical Screening Procedures for Antidepressants, Neuroleptics, and Benzodiazepines (2003)

Our knowledge of the biochemical actions of antidepressants, neuroleptics, and anxiolytics at the cellular and molecular level has led to the development of a number of rather rapid and inexpensive in vitro and ex vivo screening procedures that have proven useful in identifying new drugs with psychotropic properties, The biochemical actions most frequently tested include effects on uptake of radiolabeled biogenic amines by nerve-ending preparations, effects on monoamine oxidase (MAO) activity, and actions on binding of radiohgands to binding sites prepared from brain tissue. In the following review, each of these, along with effects on adenylate cyclase, will be considered, and the descriptions will include examples of specific applications and a discussion of how these tests fit into the overall strategies for testing potential psychotropic drugs.
Letter from the local organizing committee of the Bat-Sheva Symposium to Marshall W. Nirenberg (1978)

Littauer invites Nirenberg to the Satellite Symposium on Biochemical Development of Nervous Tissue in Culture at the Weizmann Institute of Science in Israel.
The μ-Calculus Alternation Hierarchy Collapses over Structures with Restricted Connectivity (2012)

It is known that the alternation hierarchy of least and greatest fixpoint operators in the mu-calculus is strict. However, the strictness of the alternation hierarchy does not necessarily carry over when considering restricted classes of structures. A prominent instance is the class of infinite words over which the alternation-free fragment is already as expressive as the full mu-calculus. Our current understanding of when and why the mu-calculus alternation hierarchy is not strict is limited. This paper makes progress in answering these questions by showing that the alternation hierarchy of the mu-calculus collapses to the alternation-free fragment over some classes of structures, including infinite nested words and finite graphs with feedback vertex sets of a bounded size. Common to these classes is that the connectivity between the components in a structure from such a class is restricted in the sense that the removal of certain vertices from the structure's graph decomposes it into graphs in which all paths are of finite length. Our collapse results are obtained in an automata-theoretic setting. They subsume, generalize, and strengthen several prior results on the expressivity of the mu-calculus over restricted classes of structures.
Study of Nonlinear Effects in Electrokinetics (2007)

We present an experimental and numerical investigation of induced charge electroosmosis (ICEO) on a planar electrode surface directly in contact with a high conductivity electrolytic solution. Symmetric rolls of ICEO flow were produced on the electrode by placing it in an AC electric field. The slip velocity was measured for a range of AC voltages and frequencies using micro particle image velocimetry ( μPIV). The slip velocity was also calculated by finite element simulations based on a linear and a nonlinear model of electrical double layer, respectively. The μPIV measurements were found to be much lower (two and half orders of magnitude) than the velocities predicted by the linear model. The linear model is valid only under Debye Huckel approximation ( / 25 mVolt B k T e φ = � at room temperature) which does not hold true for practical situations. The nonlinear model, on the other hand, predicts velocities which are lower than the linear model and closer to the experimental values. The nonlinearity reduces discrepancy between experimental and numerical results by approximately an order of magnitude. The nonlinear model accounts for nonlinear capacitance of the double layer and lateral conduction of charge in the double layer.
ChemInform Abstract: TUMOR‐INHIBITOREN 69. MITT. BEZIEHUNGEN ZWISCHEN SESQUITERPEN‐LACTONEN (1972)

Abstract Für eine Vielzahl von Sesquiterpen‐lactonen, z.B. (I)‐(IV), werden Relationen zwischen Cxtotoxizität und Struktur diskutiert.
Intravesical Adriamycin for Multiply Recurrent Superficial Bladder Cancer – Evaluation At 6 Years of Follow Up (1987)

No AccessJournal of Urology1 Jun 1987Intravesical Adriamycin for Multiply Recurrent Superficial Bladder Cancer – Evaluation At 6 Years of Follow Up Marc B. Garnick and Jerome P. Richie Marc B. GarnickMarc B. Garnick More articles by this author and Jerome P. RichieJerome P. Richie More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)75449-3AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "Intravesical Adriamycin for Multiply Recurrent Superficial Bladder Cancer – Evaluation At 6 Years of Follow Up." The Journal of Urology, 137(6), p. 178A © 1987 by The American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 137Issue 6June 1987Page: 178A Advertisement Copyright & Permissions© 1987 by The American Urological Association Education and Research, Inc.MetricsAuthor Information Marc B. Garnick More articles by this author Jerome P. Richie More articles by this author Expand All Advertisement PDF downloadLoading ...
Homolytic aromatic substitution of heterocyclic compounds. Part I. Decomposition of phenylazotriphenylmethane in thiophen (1969)

The reaction of thiophen with phenylazotriphenylmethane has been investigated. The percentage of the 2-phenyl-thiophen relative to that of the 3-isomer is considerably lower than those obtained with other phenylating agents and is highly dependent on the experimental conditions as well as on the working-up of the reaction mixtures. This is attributed to the trapping of the σ-complex leading to the 2-phenylthiophen by the triphenylmethyl radical to give two isomeric 2,5-dihydro-2-phenyl-5-triphenylmethylthiophens.
Cloning and Expression in<i>Escherichia coli</i>of<i>Clostridium stercorarium</i>Strain F-9 Genes Related to Xylan Hydrolysis (1990)

Journal Article Cloning and Expression in Escherichia coli of Clostridium stercorarium Strain F-9 Genes Related to Xylan Hydrolysis Get access Kazuo Sakka, Kazuo Sakka Department of Bio science, Faculty of Bioresources, Mie University, Tsu 514, Japan Search for other works by this author on: Oxford Academic Google Scholar Yuzo Kojima, Yuzo Kojima Department of Bio science, Faculty of Bioresources, Mie University, Tsu 514, Japan Search for other works by this author on: Oxford Academic Google Scholar Kazuhiro Yoshikawa, Kazuhiro Yoshikawa Department of Bio science, Faculty of Bioresources, Mie University, Tsu 514, Japan Search for other works by this author on: Oxford Academic Google Scholar Kyo Shimada Kyo Shimada Department of Bio science, Faculty of Bioresources, Mie University, Tsu 514, Japan Search for other works by this author on: Oxford Academic Google Scholar Agricultural and Biological Chemistry, Volume 54, Issue 2, 1 February 1990, Pages 337–342, https://doi.org/10.1080/00021369.1990.10869971 Published: 01 February 1990 Article history Received: 11 July 1989 Published: 01 February 1990
Analysis of the surveillance situation for viral encephalitis and meningitis in Europe (2008)

Infective processes in the brain, spinal cord and meninges are considered to be the main causes of encephalitis, myelitis and meningitis. However, most cases remain unexplained. The incidence of different viral aetiologies (zoonotic and non-zoonotic) is especially poorly estimated, due to the lack of a standard case definition and of agreed diagnostic algorithms, including harmonised diagnostic methods and sample collection. It is important to clarify the incidence of viral encephalitis/meningitis and to optimise the diagnosis of infectious neurological illness, particularly to ensure early recognition of outbreaks or emerging infectious such a West Nile encephalitis. The European Network for Diagnostics of 'Imported' Viral Diseases (ENIVD) has analysed the present surveillance situation for viral encephalitis/meningitis in Europe. Here we give an overview of the existing epidemiological sources of information in European Union (EU) Member States, mapping the laboratory capacity and identifying key requirements for a possible future surveillance study at European level. The data presented will help design a harmonised/standardised Europe-wide surveillance study investigating patients with encephalitis and/or meningitis in order to obtain more information on the role of infections in these rarely analysed syndromes, both from a clinical and an epidemiological perspective.
An Integrated Sequence in the Mathematical Sciences for Undergraduate Business Students (1973)

(1973). An Integrated Sequence in the Mathematical Sciences for Undergraduate Business Students. The American Mathematical Monthly: Vol. 80, No. 4, pp. 431-433.
Adhérence des globules rouges dans la Drépanocytose : rôle de Lu/BCAM et action de l'hydroxycarbamide (2011)

Les phenomenes d'adherence entre les globules rouges (GR) drepanocytaires et la paroi vasculaire interviennent dans la physiopathologie des accidents d'ischemie-reperfusion caracteristiques de la maladie. Parmi les molecules d'adherence, Lu/BCAM est le seul ligand erythrocytaire de la laminine. Cependant aucune etude n'a montre son implication dans les manifestations cliniques de la drepanocytose. Enfin, l'effet de l'hydroxycarbamide (HC) sur la fonction de Lu/BCAM n'a pas ete etudie. Nous avons montre que l'adherence des GR drepanocytaires a la laminine est augmentee au cours des crises vaso-occlusives severes et chez les patients ayant des atteintes viscerales severes a l'etat basai. Les patients traites par l'HC ont une adherence diminuee. Il existe une augmentation paradoxale de Lu/BCAM sous HC. Cependant l'HC diminue la phosphorylation de Lu/BCAM dans les GR de facon parallele a la diminution d'adherence. Cette diminution de phosphorylation est liee a l'inhibition d'une voie d'activation PKA/AMPc dependante. Nous avons confirme cette diminution d'adherence et de phosphorylation sous HC dans un modele cellulaire erythroleucemique (K562). Enfin nous avons montre que la voie d'activation de Lu/BCAM par phosphorylation etait presque exclusivement presente dans les reticulocytes. Ce travail montre pour la premiere fois que la fonction d'adherence de Lu/BCAM a la laminine est correlee a la gravite clinique. D'autre part il demontre l'action de l'HC sur l'inhibition de la fonction d'adherence de Lu/BCAM, par un mecanisme distinct de l'expression de l'hemoglobine fœtale, ouvrant ainsi de nouvelles perspectives therapeutiques.