gebhart/patrepeval huggingface dataset:
Differences in Global Gene Expression in Peripheral Blood Mononuclear Cells Indicate a Significant Role of the Innate Responses in Progression of Dengue Fever but Not Dengue Hemorrhagic Fever (2008)

We hypothesize that, during DF, genes in the IFN system and complement inhibitor play a role in lowering virus production and reducing tissue damage. In patients with DHF, the dysfunction of immune cells, complement, and cytokines increases viral load and tissue damage.
Regional gastrointestinal permeability of rifampicin and isoniazid (alone and their combination) in the rat. (2003)

The study shows higher in situ RMP disappearance in the presence of INH, attributable to drug degradation due to catalysis by INH. As the two drugs show regional specific permeability, FDCs without reduced RMP bioavailability resulting from its decomposition in the presence of INH can be designed by segregating delivery of the two drugs by around 3-4 h. RMP should be released in the stomach and INH in the intestine.
Raisin marketing: Program for exportable surplus may require government sponsored agency (1949)

California Agriculture - All Issues
Versuche zur Synthese von Steroiden, IX. Mitteil.: 2‐[2‐Methyl‐cyclopentyl]‐9‐methyl‐Δ<sup>4.10</sup> bzw. <sup>5.10</sup>‐oktalon‐(1) (1956)

Abstract Der über [2‐Methyl‐cyclopentyliden]‐cyanessigsäure‐äthylester zugängliche [2‐Methyl‐cyclopentyl]‐malonsäure‐diäthylester wird mit β‐[2‐Methyl‐Δ 1 ‐cyclohexenyl]‐äthylbromid zum [β‐2‐methyl‐Δ 1 ‐cyclohexenyl‐äthyl]‐[2‐methyl‐cyclopentyl]‐malonsäure‐diäthylester umgesetzt; Verseifung, Decarboxylierung und Cyclisierung liefert das ungesättigte Keton.
Role of Matriptase-2 (TMPRSS6) in Iron Metabolism (2009)

Iron, an essential element for life, is regulated primarily at the level of uptake, storage, and transport in order to maintain sufficient availability for normal physiology. The key protein in iron homeostasis is a 25-amino-acid peptide, hepcidin, which modulates the amount of iron in the circulation by binding and promoting the degradation of the iron exporter ferroportin. Given the central importance of hepcidin, recent studies have focused on how iron is sensed and how the iron signal is transmitted to hepcidin. Mutations in a type II serine protease, matriptase-2/TMPRSS6, were recently identified to be associated with severe iron deficiency caused by inappropriately high levels of hepcidin expression. A key biologically relevant substrate for the proteolytic activity of matriptase-2/TMPRSS6 was found to be hemojuvelin, a cell surface protein that regulates hepcidin expression through a BMP/SMAD pathway. In this review, we discuss the putative role of matriptase-2/TMPRSS6 in iron homeostasis.
Synoptic Monitoring of Gross Primary Productivity of Maize Using Landsat Data (2008)

There is a growing interest in monitoring the gross primary productivity (GPP) of crops due mostly to their carbon sequestration potential. Both within- and between-field variability are important components of crop GPP monitoring, particularly for the estimation of carbon budgets. In this letter, we present a new technique for daytime GPP estimation in maize based on the close and consistent relationship between GPP and crop chlorophyll content, and entirely on remotely sensed data. A recently proposed chlorophyll index (CI), which involves green and near-infrared spectral bands, was used to retrieve daytime GPP from Landsat Enhanced Thematic Mapper Plus (ETM+) data. Because of its high spatial resolution (i.e., 30 30 m/pixel), this satellite system is particularly appropriate for detecting not only between- but also within-field GPP variability during the growing season. The CI obtained using atmospherically corrected Landsat ETM+ data was found to be linearly related with daytime maize GPP: root mean squared error of less than 1.58 in a GPP range of 1.88 to 23.1 ; therefore, it constitutes an accurate surrogate measure for GPP estimation. For comparison purposes, other vegetation indices were also tested. These results open new possibilities for analyzing the spatiotemporal variation of the GPP of crops using the extensive archive of Landsat imagery acquired since the early 1980s.
Recent Development of Cognitive and Neuropsychological Assessment in Asian Countries. (2003)

There is a growing trend of research in neuropsychological assessment in Asia: The mean number of published studies increased from 1.8 in the 1980s to 16.0 in 2 recent years. About 40% of the studies reviewed concerned test development or adaptation, with the latter greatly outnumbering the former. To facilitate the test selection for clinical use, 36 clinical measures were evaluated based on some statistical criteria. The results showed that only 8 neuropsychological tests (5 Chinese, 2 Korean, and 1 Japanese) met the criteria. Given that Asian and Western populations differ on certain cognitive processes, future development of neuropsychological assessment measures in Asia should move from the adaptation of Western tests toward the construction of original tests with better ecological validity.
PageRank and rank-reversal dependence on the damping factor (2012)

PageRank (PR) is an algorithm originally developed by Google to evaluate the importance of web pages. Considering how deeply rooted Google's PR algorithm is to gathering relevant information or to the success of modern businesses, the question of rank stability and choice of the damping factor (a parameter in the algorithm) is clearly important. We investigate PR as a function of the damping factor d on a network obtained from a domain of the World Wide Web, finding that rank reversal happens frequently over a broad range of PR (and of d). We use three different correlation measures, Pearson, Spearman, and Kendall, to study rank reversal as d changes, and we show that the correlation of PR vectors drops rapidly as d changes from its frequently cited value, d_{0}=0.85. Rank reversal is also observed by measuring the Spearman and Kendall rank correlation, which evaluate relative ranks rather than absolute PR. Rank reversal happens not only in directed networks containing rank sinks but also in a single strongly connected component, which by definition does not contain any sinks. We relate rank reversals to rank pockets and bottlenecks in the directed network structure. For the network studied, the relative rank is more stable by our measures around d=0.65 than at d=d_{0}.
Foreword to the second edition (2010)

The extension of the authority to prescribe has moved on apace since the publication of the Review of the Prescribing, Supply and Administration of Medicines in 1999. Now nurses, pharmacists, allied health professionals and optometrists, as well as doctors and dentists, can prescribe. These rapid developments have set challenges for professional and regulatory bodies and for individual practitioners. However, all concerned have risen to these challenges with energy and enthusiasm. Training programmes are well developed, many nurses, pharmacists and allied health professionals have completed training, and the benefits to patients are already being felt.
Preparation of Gochujang Sauce and its Characteristics (2004)

To develope a sauce using Gochujang which can give foreigners good overall acceptance such as good flavor, taste, color, viscosity and versatility to many foods, we studied on the rheological properties and color control, recipes with spices, herbs, syrup, salt and flavor ingredients and sensory evaluation by Chinese, American and Japanese including Korean. From the survey, the Americans suggested that the proper fellow food of Gochujang sauce be fried chicken, barbecue, hamburger and pina, and hoped to reflect red color, low viscosity, hot taste, low sweetness, salty and sourness and diet effect. The Chinese suggest pork and fried food as a fellow with Gochujang sauce and showed similar opinion in the sensory attributes like the Americans except sweetness. When 5% of starch and xanthan gum was added to sauce, respectively, the yield stress of Gochujang sauce showed 33.21 Pa similar to tomato ketchup. In fluidity measured by voistic flow meter, Gochujang sauce showed 6.2 cm/30sec more or less faster than tomato ketchup which showed 4.7 cm/30sec. Gochujang sauce tended to show strong red color and lightness as pH decreased. The pH adjustant and Paprica oleoresin(2%) improved a value to 12.11 and L value to 24.24 similar to tomato kechup(a:12.42, L:25.48). The 1st gochujang sauce product show 4.50 to 5.75 pots in the overall acceptance in the consumer test including foreigners and koreans. However, the 2nd Gochujang sauce product showed 5.90 points and 6.30 points in the pina and fried chicken, respectively, in the same consumer test. Therefore, we propose that Gochujang can be used for developing sauce products which is most acceptable for various foreigners.
AMCs for ultra-thin and broadband RAM design (2009)

A novel methodology for ultra-thin and broadband radar absorbing material (RAM) design is proposed. The method is based on periodically arranging two different types of thin planar slabs that are both artificial magnetic conductors (AMCs) with different phase characteristics that are arranged in a checkerboard configuration. By controlling the phase difference between the two types of AMC slabs, the energy which is normally incident on the screen is redirected, and the RCS along the boresight is reduced over a wide frequency range.
Acoustic Sound Source Localisation and Tracking : in Indoor Environments (2008)

With advances in micro-electronic complexity and fabrication, sophisticated algorithms for source localisation and tracking can now be deployed in cost sensitive appliances for both consumer and commercial markets. As a result, such algorithms are becoming ubiquitous elements of contemporary communication, robotics and surveillance systems. Two of the main requirements of acoustic localisation and tracking algorithms are robustness to acoustic disturbances (to maximise localisation accuracy), and low computational complexity (to minimise power-dissipation and cost of hardware components). The research presented in this thesis covers both advances in robustness and in computational complexity for acoustic source localisation and tracking algorithms. This thesis also presents advances in modelling of sound propagation in indoor environments; a key to the development and evaluation of acoustic localisation and tracking algorithms. As an advance in the field of tracking, this thesis also presents a new method for tracking human speakers in which the problem of the discontinuous nature of human speech is addressed using a new state-space filter based algorithm which incorporates a voice activity detector. The algorithm is shown to achieve superior tracking performance compared to traditional approaches. Furthermore, the algorithm is implemented in a real-time system using a method which yields a low computational complexity. Additionally, a new method is presented for optimising the parameters for the dynamics model used in a state-space filter. The method features an evolution strategy optimisation algorithm to identify the optimum dynamics’ model parameters. Results show that the algorithm is capable of real-time online identification of optimum parameters for different types of dynamics models without access to ground-truth data. Finally, two new localisation algorithms are developed and compared to older well established methods. In this context an analytic analysis of noise and room reverberation is conducted, considering its influence on the performance of localisation algorithms. The algorithms are implemented in a real-time system and are evaluated with respect to robustness and computational complexity. Results show that the new algorithms outperform their older counterparts, both with regards to computational complexity, and robustness to reverberation and background noise. The field of acoustic modelling is advanced in a new method for predicting the energy decay in impulse responses simulated using the image source method. The new method is applied to the problem of designing synthetic rooms with a defined reverberation time, and is compared to several well established methods for reverberation time prediction. This comparison reveals that the new method is the most accurate.
(1<i>R</i>,2<i>R</i>)-(−)-<i>N</i>,<i>N</i>'-Bis(3,5-di-<i>tert</i>-butylsalicylidene)-1,2-cyclohexanediamine: a Salen Ligand of Jacobsen's Catalyst (1997)

In the title compound, C36H54N2O2, two salicylideneimine moieties are situated nearly perpendicular to each other so that one of them has to be rotated for complexation. There are O—H⋯N intramolecular hydrogen bonds in both salicylideneimine moieties.
Mechanical Properties of Mortar Containing Bio-Char From Pyrolysis (2012)

바이오매스에서 얻어지는 바이오차는 토질 개량제와 탄소 격리제로 제한적인 분야에서 성공적으로 사용되고 있다. 현재 산업전반에서 CO2 에 의한 환경에 부정적인 영향을 완화시키고 지속가능성을 증진시키기 위한 연구가 활발히 진행되고 있다. 이에 본 연구에서는 고탄소 바이오차를 탄소 격리제 또는 시멘트의 혼화재로써 활용 가능성을 평가하고자 하였다. 견목재에서 얻어진 바이오차를 혼화재로 사용하여 시멘트 배합조건을 달리하면서 모타르의 압축강도, 마이크로구조, 압축강도, 유동성, 중량감소와 같은 화학적, 물리적 재료성질을 평가하였다. 또한 플리이애쉬를 사용한 모르타르의 역학적 특성과 비교 평가하였다. Bio-char, obtained from biomass as a by-product of the pyrolysis process, is used successfully as a soil amendment and carbon sequester in this limited study. Recent and active research from literatures has extended the application of bio-char in the industry to promote sustainability and help mitigate the negative environmental impacts caused by carbon emissions. This study aims to investigate the feasibility of high-carbon bio-char as a carbon sequester and/or admixture in mortar and concrete to improve the sustainability of concrete. This paper presents the experimental results of an initial attempt to develop a cement admixture using bio-char. In particular, the effects of the water retention capacity of bio-char in concrete are investigated. The chemical and mechanical properties (e.g., the chemical components, microstructure, concrete weight loss, compressive strength and mortar flow) are examined using sample mortar mixes with varying replacement rates of cement that contains hardwood bio-char. The experimental results also are compared with mortar mixes that contain fly ash as the cement substitute.
Molecular mechanisms of antigen retrieval: antigen retrieval reverses steric interference caused by formalin-induced cross-links (2009)

The overwhelming majority of antibodies useful for formalin fixed, paraffin embedded (FFPE) tissues require antigen retrieval to reverse the effect of formalin fixation and re-establish immunoreactivity. How this reversal happens is poorly understood. We developed a new experimental model for studying the mechanism of formalin fixation and antigen retrieval. Epitope mapping studies on nine antibodies useful for FFPE tissues revealed that each consisted of a contiguous stretch of amino acids in the native protein (linear epitope). Small peptides representing the epitopes of antibodies to human epidermal growth factor receptor type (HER2), estrogen, and progesterone receptors were attached covalently to glass microscope slides in a peptide array. Most peptides retained immunoreactivity after formalin fixation. Immunoreactivity was completely abrogated for all peptides, however, if an irrelevant large protein was present during formalin-induced cross-linking. We hypothesize that cross-linking the irrelevant protein to the peptide epitopes sterically blocked antibodies from binding. Antigen retrieval dissociates irrelevant proteins and restores immunoreactivity. Because the epitopes for clinical antibodies require only primary protein structure, the fact that antigen retrieval probably denatures the secondary and tertiary structure of the protein is irrelevant. The same mechanism may occur in tissue samples subjected to formalin fixation and antigen retrieval.
Model-driven business process integration and management: A case study with the Bank SinoPac regional service platform (2004)

Business process integration and management (BPIM) is a critical element in enterprise business transformation. Small and medium-sized businesses have their own requirements for BPIM solutions: The engagement methodology should be fast and efficient; a reusable and robust framework is required to reduce cost; and the whole platform should be lightweight so that one can easily revise, develop, and execute solutions. We believe that model-driven technologies are the key to solving all of the challenges mentioned above. Model Blue, a set of model-driven business integration and management methods, frameworks, supporting tools, and a runtime environment, was developed by the IBM China Research Laboratory (CRL) in Beijing to study the efficacy of model-driven BPIM. To verify the technology and methodology, Model Blue was deployed with Bank SinoPac, a mid-sized bank headquartered in Taiwan. A lightweight BPIM solution platform was delivered for Bank SinoPac to design, develop, and deploy its business logic and processes. During the eight-month life span of the project, IBM teams developed four major solutions for Bank SinoPac, which also developed one solution independently. In spite of the remote working environment and the outbreak of the Severe Acute Respiratory Syndrome illness, the project was completed successfully on schedule and within budget, with up to 30% efficiency improvement compared with similar projects. Bank SinoPac was satisfied with the technology and methodology, and awarded IBM other projects. In this paper, we illustrate how each key business process integration and solution development phase was carried out and guided by business process modeling, together with major experiences gained. The following technical aspects are discussed in detail: a two-dimensional business process modeling view to integrate flow modeling and data modeling; a lightweight processing logic automation environment with tooling support; and the end-to-end BPIM methodology, with models and documents successfully integrated as part of (or replacement for) the deliverables defined in the existing servicing methodologies and software engineering approaches.
The Fringed Tapeworm (Thysanosoma actinioides) as a Parasite of the Rocky Mountain Elk in Yellowstone National Park (1969)

Post-mortem examination of 181 elk (Cervus canadensis nelsoni) from the northern Yellowstone Park herd in 1967–68 revealed that 41% were infected with Thysanosoma actinioides. Infections occurred in all age classes of animals from seven areas in the Yellowstone, Gardner and Lamar drainages in the northern section of the Park. Prevalence of the parasite was higher in calves and yearlings than in mature elk. Infections varied from 1 to 16 worms per animal, with an average intensity of 4.3 in 75 elk. Worms were confined to the first 6.2 feet of the small intestine, with no distinct habitat preference apparent within this area. Little evidence of T. actinioides or gross lesions associated with its presence was found in the liver or bile ducts of elk examined 20 to 40 minutes after death.
[Clinical efficacy and safety of huperzine Alpha in treatment of mild to moderate Alzheimer disease, a placebo-controlled, double-blind, randomized trial]. (2002)

A safe and effective medicine, huperzine Alpha remarkably improves the cognition, behavior, ADL,and mood of AD patients.
Socializing new chairs (2004)

Abstract This chapter, which focuses on the socialization process for new chairs, offers suggestions and recommendations for practice.
Simulating the GPS constellation for high fidelity operator training (2002)

This paper describes the development of the high fidelity GPS simulator Loral. The simulator will build upon existing ground system simulator software, and will take advantage of actual GPS spacecraft software developed by the satellite and payload manufacturers. Using multiprocessor computers, the system will simulate the entire satellite constellation to provide training in managing GPS worldwide navigation performance. At the same time, up to 4 complete satellite simulations can be run simultaneously to train in routine and anomalous operations of the satellites and satellite subsystems. Finally, all ground resources outside the walls of the RIGS are simulated. The simulator's user interface will allow instructors to easily input all types of anomalies to test the reaction of the students. The simulator will allow GPS operators to train individually, or as a unit, in handling true "day-in-the-life" scenarios prior to becoming certified. In addition, this paper discusses how the simulator will allow high fidelity testing of control system upgrades, reducing the need for operational resources during test. Finally, it discusses how the simulator can be adapted to support other less traditional applications.
The Dipole Moments of the Isomers of Dicarbadecaborane, B<sub>10</sub>H<sub>10</sub>C<sub>2</sub>H<sub>2</sub> (1965)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe Dipole Moments of the Isomers of Dicarbadecaborane, B10H10C2H2A. W. Laubengayer and W. R. RyszCite this: Inorg. Chem. 1965, 4, 10, 1513–1514Publication Date (Print):October 1, 1965Publication History Published online1 May 2002Published inissue 1 October 1965https://pubs.acs.org/doi/10.1021/ic50032a043https://doi.org/10.1021/ic50032a043research-articleACS PublicationsRequest reuse permissionsArticle Views120Altmetric-Citations45LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts