gebhart/patrepeval huggingface dataset:
Voltage‐sensitive conductances increase the sensitivity of rod photoresponses following pigment bleaching (2017)

A majority of our visual experience occurs during the day when a substantial fraction of the visual pigment in our photoreceptor cells is bleached. Under these conditions it is widely believed that rods are saturated and do not contribute substantially to downstream signalling. However, behavioural experiments on subjects with only rod function reveals that these individuals unexpectedly retain substantial vision in daylight. We sought to understand this discrepancy by characterizing the sensitivity of rod photoresponses following exposure to bright bleaching light. Measurements of the rod outer segment photocurrent in transgenic mice, which have only rod function, revealed the well-studied reduction in the sensitivity of rod photoresponses following pigment bleaching. However, membrane voltage measurements showed that the desensitization of the photovoltage was considerably less than that of the outer segment photocurrent following equivalent pigment bleaching. This discrepancy was largely eliminated during the blockade of cation channels due to the internal dialysis of Cs<sup>+</sup> , which increased the bleach-induced desensitization of the photovoltage and slowed its temporal characteristics. Thus, sensitization of the photovoltage by rod inner segment conductances appears to extend the operating range of rod phototransduction following pigment bleaching.
The Cytolethal Distending Toxin Induces Receptor Activator of NF-κB Ligand Expression in Human Gingival Fibroblasts and Periodontal Ligament Cells (2004)

Actinobacillus actinomycetemcomitans is associated with localized aggressive periodontitis, a disease characterized by rapid loss of the alveolar bone surrounding the teeth. Receptor activator of NF-kappaB Ligand (RANKL) and osteoprotegerin (OPG) are two molecules that regulate osteoclast formation and bone resorption. RANKL induces osteoclast differentiation and activation, whereas OPG blocks this process by acting as a decoy receptor for RANKL. The purpose of this study was to investigate the effect of A. actinomycetemcomitans on the expression of RANKL and OPG in human gingival fibroblasts and periodontal ligament cells. RANKL mRNA expression was induced in both cell types challenged by A. actinomycetemcomitans extract, whereas OPG mRNA expression remained unaffected. Cell surface RANKL protein was also induced by A. actinomycetemcomitans, whereas there was no change in OPG protein secretion. A cytolethal distending toxin (Cdt) gene-knockout strain of A. actinomycetemcomitans did not induce RANKL expression, in contrast to its wild-type strain. Purified Cdt from Haemophilus ducreyi alone, or in combination with extract from the A. actinomycetemcomitans cdt mutant strain, induced RANKL expression. Pretreatment of A. actinomycetemcomitans wild-type extract with Cdt antiserum abolished RANKL expression. In conclusion, A. actinomycetemcomitans induces RANKL expression in periodontal connective tissue cells. Cdt is crucial for this induction and may therefore be involved in the pathological bone resorption during the process of localized aggressive periodontitis.
Recovery after ECT: comparison of propofol, etomidate and thiopental Recuperação pós-eletroconvulsoterapia: comparação entre propofol, etomidato e tiopental (2008)

OBJECTIVES: To compare post anesthetic time for patient recovery after electroconvulsive therapy, as measured by the post anesthetic Recovery Score of Aldrete and Kroulik, using three different types of hypnotic drugs (propofol, etomidate and thiopental). METHOD: Thirty patients were randomized to receive one of the three drugs (n = 10 in each group), during a course of electroconvulsive therapy treatment. Patients and raters were blinded to which drug was received. Main treatment characteristics were recorded (as total electric charge received seizure threshold, number of treatments, and the mean time for recovery) along the whole treatment. RESULTS: Thiopental and propofol were associated with a significance increase in charge needed to induce a seizure (p < 0.0001) when compared to etomidate, as well as a significant decrease of time for recovery (p = 0.042). CONCLUSIONS: These findings suggest that, although there seems to be no difference in the clinical outcome across these three drugs, propofol offers the best recovery profile. However, it makes a higher mean electric charge necessary.<br>OBJETIVOS: Comparar o tempo de recuperação dos pacientes após eletroconvulsoterapia avaliada com a escala de recuperação pós-anestésica de Aldrete e Kroulik, utilizando três tipos de medicações anestésicas (propofol, etomidato and tiopental). MÉTODO: Trinta pacientes foram randomizados para receber uma das medicações (n = 10 em cada grupo) durante uma série de tratamentos com eletroconvulsoterapia. Os pacientes e o examinador ficaram cegos para o tipo de anestésico utilizado. As principais características do tratamento foram avaliadas (como carga total de eletricidade recebida, limiar convulsivo, número de sessões e o tempo médio para recuperação) ao longo de toda a série de tratamentos. RESULTADOS: Tiopental e propofol se associaram a um aumento significativo na carga elétrica total utilizada (p < 0,0001) quando comparados com etomidato, bem como uma diminuição significativa no tempo de recuperação pós-anestésica (p = 0,042). CONCLUSÕES: Estes achados sugerem que, apesar de não haver diferença na evolução clínica entre os três grupos estudados, a droga propofol oferece o melhor perfil de recuperação apesar de requerer uma carga elétrica média maior.
Innovative Approach to Fatigue Crack Propagation in Concrete Pavements (1997)

An innovative approach to characterize the micro- and macromechanical damage phenomena resulting from fatigue cracking and relate them to the design and durability of pavements has been developed. In this approach, crack propagation and its associated damage are considered as irreversible processes, and hence the general framework of the thermodynamics of irreversible processes is used to model fatigue crack propagation behavior. A constitutive equation, the modified crack layer model, is used to extract material parameters characteristic of the pavement’s resistance to fatigue crack propagation. These parameters are the specific energy of damage, γ′, and a dissipative characteristic, β′, of the paving mixture. The general applicability of the proposed approach has been extended to examine fatigue crack propagation data of concrete reported in the literature. It is found that the proposed model describes fatigue crack propagation behavior of concrete pavements over the entire range of the crack driving force.
Using a Phantom to Compare MR Techniques for Determining the Ratio of Intraabdominal to Subcutaneous Adipose Tissue (2003)

Conventional T1-weighted spin-echo MR imaging, the current sequence used in practice for measuring visceral adiposity, may not be the optimal MR sequence for this purpose. We found that the T1-weighted fast Dixon sequence was the most accurate at estimating all fat volumes. The T1-weighted 3D spoiled gradient-echo sequence generated similar ratios of intraabdominal to subcutaneous adipose tissue in a fraction of the acquisition time.
Simultaneous binding of platinum(II) to three different sites (N7, N1, N3) of a guanine nucleobase (1985)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSimultaneous binding of platinum(II) to three different sites (N7, N1, N3) of a guanine nucleobaseGabriele Raudaschl-Sieber, Helmut Schoellhorn, Ulf Thewalt, and Bernhard LippertCite this: J. Am. Chem. Soc. 1985, 107, 12, 3591–3595Publication Date (Print):June 1, 1985Publication History Published online1 May 2002Published inissue 1 June 1985https://pubs.acs.org/doi/10.1021/ja00298a031https://doi.org/10.1021/ja00298a031research-articleACS PublicationsRequest reuse permissionsArticle Views171Altmetric-Citations72LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
PIECEWISE POLYNOMIAL APPROXIMATIONS FOR HEAVY-TAILED DISTRIBUTIONS IN QUEUEING ANALYSIS (2005)

ABSTRACT A basic difficulty in dealing with heavy-tailed distributions is that they may not have explicit Laplace transforms. This makes numerical methods that use the Laplace transform more challenging. This paper generalizes an existing method for approximating heavy-tailed distributions, for use in queueing analysis. The generalization involves fitting Chebyshev polynomials to a probability density function g(t) at specified points t 1, t 2, …, t N . By choosing points t i , which rapidly get far out in the tail, it is possible to capture the tail behavior with relatively few points, and to control the relative error in the approximation. We give numerical examples to evaluate the performance of the method in simple queueing problems.
Efficient restoration and enhancement of super-resolved X-ray images (2008)

Our previous work demonstrates the ability to reconstruct a single higher resolution image from fusing a collection of multiple extremely low-dosage aliased X-ray images. While this computationally efficient method eliminates aliasing artifacts associated with undersampling, it does not address the problem of deblurring the reconstructed image. In this paper, we present a fast nonlinear deblurring algorithm, specifically designed to address the nonstationary noise associated with multiframe reconstructed images. The algorithm uses a combination of Fourier sharpening and wavelet denoising similar to the ForWarD algorithm. Experimental results on enhancing digital mammogram images attest to the effectiveness of the presented method.
Crystal chemistry of tetraradial species. Part 7. Lithium tetrakis(1-imidazolyl)-borate solvate, Li<sup>iv</sup>[Li<sup>iv</sup>(H<sub>2</sub>O)(MeOH)]-[B(C<sub>3</sub>H<sub>3</sub>N<sub>2</sub>)4]<sub>2</sub>•MeOH, a 3-dimensional polymer; with observations on the geometry of imidazole rings (1995)

The title compound is a 3-dimensional polymer with a completely ordered triclinic structure [Formula: see text] a = 12.380(2) Å, b = 14.434(2) Å, c = 9.683(3) Å, α = 90.36(2)°, β = 105.44(2)°, γ = 90.75(2)°, Z = 2). Every B atom is tetrahedrally coordinated by N(1) atoms of the imidazole rings, every Li(1) atom is tetrahedrally coordinated by N(3) atoms, and every Li(2) atom is coordinated by two N(3) and two oxygen atoms, one from the H 2 O molecule and one from a MeOH molecule. The imidazole rings connected by the B—N(1) and Li—N(3) bonds thus generate a 3-dimensional covalent polymeric network. The MeOH molecules of coordination are hydrogen-bonded to unengaged N(3) atoms, thereby supplementing the covalent bonding system. The H 2 O molecules are hydrogen-bonded to the MeOH molecules of solvation to form centrosymmetric [O w … O MeOH ] 2 rings, which in turn are connected to the covalent network by O MeOH —H … N(3) bonds to the remaining unengaged N(3) atoms. Every atom in the structure except the H(C) hydrogens is thus involved in the 3-dimensional bond system. The excellent consistency of the bond lengths and endocyclic bond angles [Formula: see text] in the eight imidazole rings of the title compound has provided an opportunity for investigating the effect of substitution on the geometry of the imidazole ring in a sample of 17 substituted imidazoles. While the bond lengths have been found at most weakly correlated, the multilinear correlations of the [Formula: see text] in this sample are highly significant. Among the substituents the NO 2 , group is the most ipso- [Formula: see text] -expanding and the anionic B (in the title compound) the most ipso- [Formula: see text] -contracting. Protonation or deprotonation at the N atoms affect the ipso C—N—C angles considerably. Limited comparisons are drawn with the results of the classical investigations by Domenicano et al. on the effect of substitution on the geometry of the benzene ring. Keywords: hydrogen bond, imidazole, lithium compounds, polymers, tetrahedral boron ions.
Comparison of the Physical and Chemical Changes Occurring in Oils During Aging in Vehicle and Engine Fuel Economy Tests (1998)

<div class="htmlview paragraph">Oils, which do not contain Molybdenum (Mo)-based friction modifiers, were aged in vehicle and engine fuel economy tests in order to determine if the different aging protocols caused similar changes in the physical and chemical properties of these oils. Vehicle and engine tests were found to cause similar changes in the high temperature high shear (HTHS) viscosities and boundary friction coefficients of oils. We also observed that the extent of oil oxidation, nitration and volatilization occurring in the vehicle tests could be duplicated by aging in the engine tests. The fuel economy performance of aged oils was also measured in engine tests and found to be highly dependent upon the aged oil's HTHS viscosity. However, we observed that an aged oil's boundary friction coefficient, by itself, did not correlate to an aged oil's fuel economy performance in the high temperature fuel economy measurement stages of engine tests.</div>
A Survey of Course Offerings in Colloid and Surface Chemistry, 1959 (1960)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTA Survey of Course Offerings in Colloid and Surface Chemistry, 1959Karol J. Mysels Cite this: J. Chem. Educ. 1960, 37, 7, 355Publication Date (Print):July 1, 1960Publication History Received3 August 2009Published online1 July 1960Published inissue 1 July 1960https://doi.org/10.1021/ed037p355RIGHTS & PERMISSIONSArticle Views28Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (2 MB) Get e-Alerts Get e-Alerts
Salt-Like Behavior of the t-Butyl Chloride Solvolysis Transition State<sup>1,2</sup> (1965)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSalt-Like Behavior of the t-Butyl Chloride Solvolysis Transition State1,2Edward M. Arnett, Wesley G. Bentrude, and Peter McC. DugglebyCite this: J. Am. Chem. Soc. 1965, 87, 9, 2048–2050Publication Date (Print):May 1, 1965Publication History Published online1 May 2002Published inissue 1 May 1965https://pubs.acs.org/doi/10.1021/ja01087a035https://doi.org/10.1021/ja01087a035research-articleACS PublicationsRequest reuse permissionsArticle Views96Altmetric-Citations27LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Protocol for a Systematic Mapping Study on Collaborative Model-Driven Software Engineering (2016)

Nowadays, collaborative modeling performed by multiple stakeholders is gaining a growing interest in both academia and practice. However, it poses a set of research challenges, such as large and complex models management, support for multi-user modeling environments, and synchronization mechanisms like models migration and merging, conflicts management, models versioning and rollback support. A body of knowledge in the scientific literature about collaborative model-driven software engineering (MDSE) exists. Still, those studies are scattered across different independent research areas, such as software engineering, model-driven engineering languages and systems, model integrated computing, etc., and a study classifying and comparing the various approaches and methods for collaborative MDSE is still missing. Under this perspective, a systematic mapping study (SMS) can help researchers and practitioners in (i) having a complete, comprehensive and valid picture of the state of the art about collaborative MDSE, and (ii) identifying potential gaps in current research and future research directions.
Spin Dependent Hopping and Colossal Negative Magnetoresistance in Epitaxial<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mrow><mml:msub><mml:mrow><mml:mi>Nd</mml:mi></mml:mrow><mml:mrow><mml:mn>0.52</mml:mn></mml:mrow></mml:msub></mml:mrow><mml:mrow><mml:msub><mml:mrow><mml:mi>Sr</mml:mi></mml:mrow><mml:mrow><mml:mn>0.48</mml:mn></mml:mrow></mml:msub></mml:mrow><mml:mrow><mml:msub><mml:mrow><mml:mi>MnO</mml:mi></mml:mrow><mml:mrow><mml:mn>3</mml:mn></mml:mrow></mml:msub></mml:mrow></mml:math>Films in Fields up to 50 T (1998)

The low carrier mobility of the magnetic perovskite ${\mathrm{Nd}}_{0.52}{\mathrm{Sr}}_{0.48}{\mathrm{MnO}}_{3}$ implies that the dominant conductivity mechanism is related to Mott hopping. We propose a modification of Mott's original model by taking into account that the hopping barrier depends on the misorientation between the spins of electrons at an initial and a final state in an elementary hopping process. Using this model we deduce a negative-magnetoresistivity scaling proportional to the Brillouin function $B$ in the ferromagnetic state and to ${B}^{2}$ in the paramagnetic state. Both predictions are in full agreement with the magnetoresistivity measured in pulsed magnetic fields up to 50 T.
Adsorption Equilibrium Modeling of Space Station Wastewaters (1999)

An adsorption equilibrium model was developed for predicting the total organic carbon (TOC) removal by the International Space Station water processor's multifiltration beds. Ideal adsorbed solution theory is used to describe the competitive interactions between fictive components (FCs) that make up the TOC. The FC physical properties were based on several identified compounds to represent the distribution adsorbing compounds in the wastewaters. The TOC isotherms were performed using the wastewaters on three absorbents (a coconut-based granular activated carbon, a coal-based granular activated carbon, and a polymeric-based resin), which are contained in the multifiltration beds. The isotherms were used to validate the model for all three adsorbents. The FCs were determined in such a way that they can describe the TOC concentration for multiple beds in series.
Assessment of Alternatives for Reducing Energy Consumption in Multi-RAT Scenarios (2014)

Modern radio base stations (RBSs) typically consist of components such as radio units (RUs) and digital units (DUs) that are capable of supporting multiple radio access technologies (RATs) at the same time. This enables several different possible configurations of a multi-RAT site and in this paper we assess the energy performance of some promising configurations. We start by evaluating an LTE-only network and conclude that with traffic according to predictions for 2015 the average cell will be idle 95% of the time and the additional energy consumption due to the user plane traffic is only 1.4%. We also show that even a significant future traffic increase will only have a minor impact on the energy consumption. We further show in this paper that a multi-RAT RBS where the RATs share the digital unit (PA) have the potential to reduce the site energy consumption with 40% compared to a multi-RAT RBS with separate PAs for each RAT. For operators with multiple RATs on the same site but using separate PAs per RAT, it is still possible to reduce energy consumption by utilizing load balancing between the RATs. This study shows that a potential energy reduction in the order of 30% is possible by utilizing load balancing between HS and LTE.
Development of a Methyl Bromide Collection System for Fumigated Farmland (2001)

Recent research has indicated that up to 73% of the methyl bromide (MeBr) applied to agricultural farmland is ultimately emitted to the atmosphere despite the practice of complete coverage of the fields with polyethylene (PE) tarp. To reduce the emission of MeBr, several techniques have been investigated. An alternative that has received little consideration is the collection and recycle or treatment of MeBr emissions. We investigated the potential of using a two-layer tarp system for collecting the MeBr. Laboratory experiments with a small two-layer diffusion reactor were conducted to determine the mass transfer coefficient (K) of MeBr through tarps and to validate a model of the collection system. For PE tarps K was 1.15 x 10(-6) m s-1 at 20 degrees C and 5.2 x 10(-6) m s-1 at 60 degrees C. K for so-called virtually impermeable films ranged from 4.6 x 10(-10) m s-1 to 1.3 x 10(-8) m s-1. The mathematical model was then used to simulate a full scale fumigant field application. Results indicate excellent agreement between the model, laboratory experiments, and previous field studies. Total emission from the field was a function of the air exchange rate through the swept volume between the two layers, the length of time the field is covered by the collection system, and the mass transfer coefficient of MeBr though the tarps. The results indicate that the proposed two-layer system can be very effective in collecting MeBr emissions from fumigated farmland.
Author Argues Have-nots Better Served by Postal Banking (2015)

Professor Mehrsa Baradaran argues that it's time to head back to the future and revive postal banking here as the cost-effective way to both free the underbanked from the abuses of fringe lenders and revitalize the U.S. Postal Service in a Q&A from Creditcards.com.