gebhart/patrepeval huggingface dataset:
Performance model of an optical switch using fiber delay lines for resolving contentions (2004)

The performance of an optical switch that handles contention resolution using a fiber delay line (FDL) is modeled and evaluated. We propose using a simple optical buffer that contains only a single FDL for contention resolution. The analytical model derived for the performance of an optical switch based on this buffer is verified using simulations. The analytical model can be utilized with both packet and burst switching schemes to characterize the performance of switches augmented with this FDL architecture.
Time-resolved spectra of high-current pulsed argon lasers (1968)

The time-resolved laser spectrum of a pulsed argon discharge has been examined in the visible region with a fast response photodiode and with an image converter camera in the streak mode. At 10 mtorr pressure of argon, laser action takes place on up to eight lines between 4579 and 5145 Å, seven of these lines being <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">4p \rightarrow 4s</tex> transitions and one a <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">4p' \rightarrow 3d</tex> transition. With peak discharge currents of 50 to 1500 amperes (400 to 12000 amperes-cm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">-2</sup> ) and duration of about 2 μs, laser action takes place both during the current pulse and in the afterglow. The primary laser output occurs during the first half of the current pulse, while the current is increasing, and then laser action ceases until the current has ceased to flow. In the afterglow, laser action recommences and lasts for up to 60 μs. The effects of variation of gas pressure, applied potential difference, and current pulse length on the threshold conditions, intensities, and duration of the lines are examined.
Comorbidities and causes of death in the management of localized <scp>T</scp>1a kidney cancer (2014)

Congestive heart failure, chronic kidney disease, peripheral vascular disease, chronic obstructive pulmonary disease, diabetes and cerebrovascular disease were associated with decreased overall survival among Medicare beneficiaries with small renal masses. The cardiovascular index could serve as a clinically useful prognostic aid when advising older patients that are borderline candidates for surgery or active surveillance.
Mesures sur les fonctions : caractérisation paramétrique des images en niveaux de gris et application aux surfaces non planes (1993)

L’analyse d’images a pour objet de les quantifier a l’aide de parametres. Pour obtenir ce resultat, on doit eliminer le bruit de l’image, extraire les objets par segmentation et enfin les mesurer. Malheureusement, toutes les images ne sont pas segmentables, en particulier les images topographiques obtenues par microscopie confocale ou microscopie electronique a balayage. Dans cet article, nous decrivons et faisons une etude critique des methodes permettant d’obtenir une quantification de l’information sur des images non segmentees en niveaux de gris.
Jet-Stirred Combustor Behavior Near Blowout: Observations and Implications (1992)

Abstract The behavior of jet-stirred combustors near blowout has been examined. Such units nominally emulate perfectly stirred reactors (PSR). Previous experimental data on instantaneous temperatures and stable species from a toroidal design have suggested non-PSR behavior as overall extinction is approached. Detailed mechanistic modeling in this work shows that such combustors experience global blowout at significantly lower mass flow rates than predicted by a PSR model. It is suggested that, as overall blowout is approached, only a fraction of the physical reactor volume is under active combustion as localized extinction occurs while apparent global stability still exists. This hypothesis is used to successfully predict observed global extinction points for C2H4/air and CO/H2/ air in a toroidal unit, and CH4/air in a spherical unit. In order to judge whether a stirred combustor is experiencing significant departures from PSR behavior, a test is offered for carbon-containing fuels burned under fuel-lean conditions. It compares the measured CO concentration with the predicted CO concentration obtained from a PSR computer simulation based on an elementary CO/H2 reaction mechanism and a modified feed composition. In this feed, the actual fuel is replaced with a stoiehiomelrically equivalent amount of CO and H2O, and the 02 feed is reduced accordingly. If localized instability is occuring, the measured CO level will exceed the predicted CO level. This test has been confirmed for fuel-lean C2H4 oxidation in air in a toroidal jet-stirred combustor.
The distribution of cosmic-ray-produced rare gases in iron meteorites (1960)

The cosmogenic Ar/sup 38/, Ar/sup 36/, Ne/sup 22/, Ne/sup 21/, Ne/sup 2/ s/sup 0/, He/sup 4/, and He/sup 3/ distribution in part of a cross section of the iron meteorite Grant was measured. The amounts were found to vary systematically with depth. The depth effect was analyzed in terms of a production mechanism, and numerical parameters were determined. Comparisons were made with the results of other investigations. Functional relationships correlating relative amounts of cosmogenic nuclides with position and size of a meteoritic body are demonstrated. In principle the determination of a sufficient number of cosmogenic nuclides in a single sample permits deductions about the radiation dosage and the size of the meteoroid as well as the location of the sample within the body. (auth)
Quantification of Variations in Machine-Vision-Computed Morphological Features of Cereal Grains (2002)

Six morphological features (area, perimeter, maximum radius, minimum radius, majoraxis length, and minor axis length) were extracted from high-resolution images of five differentcereal grains (barley, Canada Western Amber Durum (CWAD) wheat, Canada Western RedSpring (CWRS) wheat, oats, and rye). The variability in these features that can occur due to thekernel orientation, growing region, and images acquired from line- and area-scan cameras, wascalculated. The variation in features was mainly dependent on the maturity levels of kernelsbecause samples coming from different growing regions showed comparable variability to thosecoming from one growing region. The variability in features due to different image acquisitiondevices was statistically insignificant. Keywords. Digital image analysis, cereal grains, featureextraction.
Analyse bioinformatique de la régulation transcriptionnelle des complexes protéiques chez la levure Saccharomyces cerevisiae (2005)

Doctorat en Sciences
Development of monoclonal antibodies against human gastrointestinal cancer. (1990)

We have evaluated approximately 10,000 monoclonal antibodies resulting from 14 hybridization of spleen cells from mice immunized with established cancer cell lines. They were screened by binding assays using cancer cell lines or normal fibroblast cells, followed by immunohistochemical study on tissue sections. Ninety-one monoclonal antibodies were obtained by above binding assays. One of them, named KM10 was further investigated. Isotype of KM10 was IgG1 with kappa-light chain. It was shown that KM10 has strong reactivity with tumors of colon, stomach, papilla Vater, and pancreas, while the limited reactivity displayed with normal tissues. The electron microscopic observation revealed that the antigen recognized by KM10 is expressed on the surface of cancer cells. KM10 could mediate ADCC. These results indicate that KM10 is a good candidate for a probe of diagnosis and therapy of cancer.
Starch‐based backwards SHG for <i>in situ</i> MEFISTO pulse characterization in multiphoton microscopy (2008)

We report a simple methodology to provide complete pulse characterization at the sample plane of a two-photon excited fluorescence (TPEF) microscope. This is achieved by using backward propagating second-harmonic generation (SHG) from starch granules. Without any modification to the microscope, SHG-autocorrelation traces were obtained by using a single starch granule that was placed alongside the biological specimen being imaged. A spectrally resolved SHG autocorrelation was acquired by placing a spectrometer at the output port of the microscope. Complete in situ pulse information is then directly retrieved in an analytical way using the measurement of electric filed by interferometric spectral trace observation (MEFISTO) technique.
How Prevalent Are Autistic Traits Among Children With Attention-Deficit/Hyperactivity Disorder? A Qualitative Review of the Literature (2012)

Although this study was limited by the small amount of available literature about this subject, these findings suggest that a sizeable subset of children with ADHD manifest autistic traits and that the presence of these traits is associated with increased dysfunction and social and communication deficits.
On the dimensionality of spatial fields with restricted angle of arrival (2005)

Wireless communication occurs through continuous fields, over regions of space. Although the communication channel may be modelled in terms of infinite dimensional vector spaces, it is paramount to develop finite dimensional approximations for this channel. We extend previous work which examined the fundamental finite dimensionality of fields over a finite region of space to incorporate restricted angles of signal arrival. By considering a subspace of fields where direction of arrival of the field components, or source spatial distribution, is restricted we show the received field dimensionality is linearly related to the product of the radius of the region of interest and the angular restriction. This result provides a rigourous foundation for analysing the performance and capacity of MIMO systems in non isotropic environments. The proof is presented for the two dimensional case. It is apparent that this work can be extended to the case of three dimensions for a similar result
Pharmacological study on hydrocortisone 17-butyrate 21-propionate (1981)

The topical and systemic anti-inflammatory activities of hydrocortisone 17-butyrate 21-propionate (HBP) were studied. The systemic anti-inflammatory activities of HBP and reference steroids were examined for their effects on dinitrochlorobenzene dermatitis, carrageenin edema, cotton pellet granuloma and adjuvant arthritis in rats and by the delayed allergic edema test in mice. The topical anti-inflammatory activities of these steroids were examined for their effects on croton oil dermatitis, croton oil ear edema, carrageenin edema and cotton pellet granuloma in rats. Furthermore, effects of these steroids on liver glycogen deposition in mice, thymolysis, and decrease of serum corticosterone level in rats were examined. Systemically administered HBP was less potent than betamethasone 17-valerate (BV), but was almost equal to hydrocortisone 17-butyrate (HB) in anti-inflammatory activity, and its effects on liver glycogen deposition, thymolysis, and the decrease of serum corticosterone level. However, the topical anti-inflammatory activity of HBP was more potent than that of BV and HB, although in the same experiment, thymolytic activity of HBP was less potent than that of BV, but was almost equal to HB. The inhibitory effect of HBP on hypotonic induced hemolysis was weaker than that of BV, but was stronger than that of HB in vitro. The affinity of HBP was higher than that of BV and HB to polymorphonuclear leucocytes used as the inflammatory cells in vitro. On the other hand no marked difference was observed in the affinity to erythrocytes used as the non-inflammatory cells in vitro. These results suggest that HBP is a useful drug which has superior topical anti-inflammatory activity, but has a weak systemic effect.
Protein Binding Detection Using On-Chip Silicon Gratings (2011)

We demonstrate a silicon gratings-based biosensor to detect functionalized protein binding on its surface. The designed silicon gratings have sensitivities up to 197 nm/RIU in detecting refractive index change and 1.61 nm per nanometer of thickness change of bio-material on the surface of silicon gratings. Functionalizing proteins on gratings surface by eliminating unspecific binding makes this device more selective and efficient. Streptavidin at a concentration of 0.016 μmol/mL was functionalized on silicon substrate and biotin of 12 μmol/mL concentration was used as a target molecule in our detection experiments. Normal transmission measurements of gratings are made in air at different stages of immobilization, bare silicon grating, after attaching streptavidin and after trapping biotin. Total shifts in resonant peak wavelength of ∼15 nm in normal transmission were observed after immobilizing biotin with ∼7 nm of shift in resonant peak wavelength after functionalizing streptavidin to silicon substrate.
A firm, bluish, hemorrhagic nodule on the left heel (2013)

What is your diagnosis?
Slotted optical switching with pipelined two-way reservations (2006)

Optical burst switching is a core architecture designed to reconcile the available optical technology with the increasing burstiness of traffic. However, disappointing performance in terms of high packet loss and/or low system utilization discouraged broader experimental implementations. A method to avoid these losses by first sending over the control channel a short scout packet that simulates the events that the actual burst will experience is proposed in this paper. Once the scout message detects a drop at any intermediate node, it returns back to the source to avert the payload emission and repeat the process. The way the control works results in essential service quality features, i.e., no loss of bursts, no out-of-order emissions, increased efficiency, much reduced delay variation, and graceful throttling of the load respecting the contracted rates.
Early identification of wound infection: understanding wound odour (2017)

Malodorous wounds can be distressing for patients and their families, negatively impacting on quality-of-life outcomes. For health professionals malodorous wounds can also cause distress manifesting in feelings of disgust when faced with a wound emitting an unpleasant or repulsive odour. There has been investigation into the management of controlling odour particularly in relation to fungating wounds. However, there is limited research that explores techniques for early identification and recognition of wound odours that may be indicative of infection. Electronic nose technology has received some attention, but to date has not been integrated into either diagnostics of infection in wounds or education of health professionals to prepare them for the realities of clinical practice.
SEASONAL PATTERNS OF ROOT GROWTH IN RELATION TO SHOOT PHENOLOGY IN GRAPE AND APPLE (2006)

Growers plan many of their horticultural activities around certain shoot phenological stages such as bloom and veraison. Timing of root growth in relation to these stages of the shoot is of interest in fertilization scheduling and understanding carbon allocation demands of the root system. With the recent use of minirhizotron root observation tubes, a much greater understanding of patterns of root growth has been made possible. In this paper some published work and present data from ongoing studies on timing of root production are reviewed. Studies discussed include ongoing work in grape vineyards in Fredonia, New York, USA (Vitis lambruscana), and Oakville, California, USA (V. vinifera), and in apple orchards (Malus × domestica) in Summerland, British Columbia, Canada. Root production mainly occurs in the summer, but the specific timing varies widely between bloom and harvest from year to year. Usually there is little root growth in the few weeks prior to harvest and when the vines are dormant. Cultural practices may affect root production, usually from a combination of changes in the soil environment (moisture, temperature) and changes in photosynthetic capacity.
MR imaging of a subungual glomus tumor. (1999)

January 1999MR imaging of a subungual glomus tumor.Authors: G Opdenakker, G Gelin, and Y PalmersAuthor Info & AffiliationsVolume 172, Issue 1https://doi.org/10.2214/ajr.172.1.9888786 METRICS otherformats
Confocal optical sectioning and three‐dimensional reconstruction of carcinoma fragments in pap smears using sophisticated image data processing (1994)

Carcinoma fragments found in Pap smears contain important diagnostic information not available to the light microscopist because of their thickness and consequent blurring. Optical sectioning by the confocal microscope allows us to reclaim the mitotic figures, glandular architecture, and abnormal chromatin patterns in the restained original smears. The high spatial resolution of the confocal microscope can be further exploited by processing the digital images with the sophisticated Application Visualization System (AVS) on a CONVEX computer. Serial sections in which the fluorescent signals are color coded by this software package and three-dimensional reconstructions of the nuclei and mitotic figures expand our knowledge of these malignant epithelial fragments.
Survey and analysis of the efficacy and prescription pattern of sorafenib in patients with acute myeloid leukemia (2011)

Sorafenib is a multi-kinase inhibitor with activity against several intracellular kinases which may play a role in the pathogenesis of acute myeloid leukemia (AML). In vitro data and results from early clinical trials suggest that sorafenib might be an effective drug for the treatment of AML. However, clinical data are still sparse, and there are only a few reported cases of monotherapy. The aim of the present research was to collect clinical data on efficacy and safety in a systematic way by conducting a survey on clinical experience with sorafenib. Thirty institutions were asked to document all patients treated with sorafenib diagnosed with AML. Of all 29 evaluable patients, six (21%) responded to sorafenib containing treatment by achieving a complete remission (CR, n = 2) or complete remission with incomplete platelet recovery (CRi, n = 4). In 23 patients receiving sorafenib as monotherapy, the CRi rate amounted to 13% and no CRs were documented. Of the 18 FLT-ITD positive patients with sorafenib monotherapy, two patients achieved a CRi (11%). In five FLT3-ITD negative cases, one CRi was documented (20%). Our results suggest the potential ability of the drug to induce remissions in refractory or relapsed AML even when given as monotherapy.
Design of a Low-Cost Autoclave for Developing World Health Clinics (2012)

Incidence of surgical site infection is 2–5 times higher in developing nations as compared to developed nations. A low-cost, easy to use autoclave was designed to address the unique technical, behavioral, and market challenges present in rural, health posts of the developing world. A thorough stakeholder analysis was performed very early in the design process to address non-technical needs for sustained user adoption as well as manufacturability and scalability. Twelve partnering clinics in Nepal trialed these autoclaves from July until December 2012. Usage statistics and follow-up observations highlight important factors for successful adoption. These findings were used to improve the autoclave design. The goal of this paper is to detail a case study and methodology to incorporate multiple stakeholder needs into the early design process.
Ovulation induction in anestrous bitches by pulsatile administration of gonadotropin-releasing hormone. (1987)

Preliminary studies in anestrous Beagle bitches demonstrated that a single injection of gonadotropin-releasing hormone (150 micrograms) produced a rapid, physiological rise in serum estradiol lasting 1-3 days while progesterone remained below 1 ng/ml, whereas serial injections of FSH rapidly produced greater elevations in estradiol and a rapid rise in progesterone over 2 ng/ml. Consequently, attempts to induce fertile ovulation by means of pulsatile intravenous administration of GnRH (1 pulse/1.5 hours for 6-12 days; 0.04-0.43 micrograms/kg body weight/pulse) were conducted in eight anestrous bitches. Willingness to mate, serum progesterone levels and results of mating were monitored. In six of the eight bitches, vulval and vaginal signs of proestrus occurred by Day 2-4 after initiation of treatment (Day 0); but, two bitches showed negligible responses. In five of the six bitches in which proestrus was induced, behavioral (n = 4) and vaginal (n = 5) correlates of early estrus occurred by Day 5-7 of treatment and breedings occurred over a period of 4-12 days. Following onset of estrus, four of the five bitches had increases in serum progesterone levels between Days 14 and 18 after initiation of treatment (and 4-11 days after cessation of treatment); three of them became pregnant and whelped normal litters (ranging from 9 to 11 pups). The fifth bitch did not have elevated progesterone during the induced estrus, and upon return to estrus one month later was successfully bred and whelped a normal litter of 10 pups.(ABSTRACT TRUNCATED AT 250 WORDS)
Anomalous Optical Emission and Fragmentation at the Plasma-Solid Interface. (1992)

Anomalously strong optical emission from the excited CH radical was obserbed near the negatively biased electrode in a CH4/Ar glow plasma. The time evolution of the CH emission depends on the material and the surface state of the electrode as well as the applied bias voltage. A possibility of the anomalous emission by secondary electrons was denied from Monte Carlo simulation of the process. The experimental observations and calculations revealed the CH radical formation by two surface processes: fragmentation of hydrocarbon particles (ions and neutrals) at their impact on the cathode, and sputtering of the already deposited carbon film. These processes are essential for understanding the redeposition mechanisms in carbonized environement.
Obstetric Drugs and Infant Behavior: A Reevaluation (1991)

This chapter focuses on two issues underlying skepticism: problems of the confounding of obstetric drugs and various factors and faulty statistical analysis. Strong claims have been made about adverse effects of obstetric drugs on the behavioral development of children. Poorly designed and analyzed studies ascribing effects of obstetric drugs on infant behavior may not only have misrepresented facts but may also have rendered well-designed and analyzed studies difficult to execute. Obstetric drug decisions are determined by the difficulty of individual labors. The proliferation of poorly controlled studies purporting to demonstrate adverse effects of obstetrical medication have made it nearly impossible to execute further such trials. Drug use should be associated with any factor causative of, associated with, or resultant from, difficult labors: the health status or age of mother, parity, length of labor, level of anxiety, pain or tolerance for pain, and possibly socioeconomic status and home environments.
Risk perception and health behaviour (2001)

Health depends, in part, on deliberate decisions. Some are private, such as deciding whether to wear bicycle helmets and seat belts, follow safety warnings, use condoms and fry (or broil) food. Other decisions involve societal issues, such as whether to protest about the siting of an incinerator or halfway house, vote for fluoridation and ‘green’ candidates or support sex education.