gebhart/patrepeval huggingface dataset:
New fabrication method for highly oriented <i>J</i> aggregates dispersed in polymer films (1993)

We present a new fabrication method, called ‘‘vertical spin coating,’’ to prepare highly oriented J aggregates dispersed in polymer films. Linear dichroic spectra of the oriented J aggregate of 1,1′-diethyl-2,2′-quinocyanine bromide PIC-Br were measured at 5 K. The dichroic ratio at the peak of J band was 5 to 10, dependent on the preparation conditions. Precise measurement of the dichroism at the J band revealed that the J band is composed of two bands with transition dipole moments perpendicular to each other. The films are stable even at room temperature, and have applications as nonlinear optical devices.
ChemInform Abstract: DIBENZ(B,E)OXEPINALKANOIC ACIDS AS NONSTEROIDAL ANTIINFLAMMATORY AGENTS. 1. 6,11‐DIHYDRO‐11‐OXODIBENZ(B,E)OXEPIN‐2‐ACETIC ACIDS (1977)

Abstract Aus den Bromtolylcarbonsäureestern (I) und p‐Hydroxyphenylessigestern (II) werden durch Kondensation und Hydrolyse die Dicarbonsäuren (III) hergestellt und durch Behandlung mit Phosphorpentoxid/Äthanol zu Dihydro‐oxodibenzoxepinderivaten (IV) cyclisiert, aus denen Amide und verschiedene Ester (VII) hergestellt werden.
Electron-transfer kinetics of 4,4'-bis(alkoxycarbonyl)-2,2'-bipyridine-iron complexes in micellar solution (1985)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTElectron-transfer kinetics of 4,4'-bis(alkoxycarbonyl)-2,2'-bipyridine-iron complexes in micellar solutionMarco Vincenti, Edmondo Pramauro, Ezio Pelizzetti, Stephan Diekmann, and Jens FrahmCite this: Inorg. Chem. 1985, 24, 26, 4533–4537Publication Date (Print):December 1, 1985Publication History Published online1 May 2002Published inissue 1 December 1985https://pubs.acs.org/doi/10.1021/ic00220a023https://doi.org/10.1021/ic00220a023research-articleACS PublicationsRequest reuse permissionsArticle Views90Altmetric-Citations6LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mrow><mml:msup><mml:mrow><mml:mi mathvariant="normal">N</mml:mi></mml:mrow><mml:mrow><mml:mn>14</mml:mn></mml:mrow></mml:msup></mml:mrow><mml:mo>(</mml:mo><mml:mrow><mml:msup><mml:mrow><mml:mi mathvariant="normal">He</mml:mi></mml:mrow><mml:mrow><mml:mn>3</mml:mn></mml:mrow></mml:msup></mml:mrow><mml:mo>,</mml:mo><mml:mi> </mml:mi><mml:mi>n</mml:mi><mml:mo>)</mml:mo><mml:mrow><mml:msup><mml:mrow><mml:mi mathvariant="normal">F</mml:mi></mml:mrow><mml:mrow><mml:mn>16</mml:mn></mml:mrow></mml:msup></mml:mrow></mml:math>Reaction (1965)

Time-of-flight neutron spectra from the bombardment of a chromium nitride target by 3.5- and 6.2-MeV ${\mathrm{He}}^{3}$ particles indicate five neutron groups corresponding to the ground state of ${\mathrm{F}}^{16}$ and to excited states at 0.20\ifmmode\pm\else\textpm\fi{}0.05, 0.436\ifmmode\pm\else\textpm\fi{}0.030, 0.736\ifmmode\pm\else\textpm\fi{}0.040, and 3.78\ifmmode\pm\else\textpm\fi{}0.06 MeV, with widths of 50\ifmmode\pm\else\textpm\fi{}30, 40, 40\ifmmode\pm\else\textpm\fi{}30, 15 and 40 keV, respectively. The ground state $Q$ value is -0.963\ifmmode\pm\else\textpm\fi{}0.040 MeV, corresponding to a ${\mathrm{F}}^{16}$ atomic mass excess of 10.686\ifmmode\pm\else\textpm\fi{}0.040 MeV. The results are discussed in terms of the known information on the $T=1$ states in the $A=16$ isobaric triad.
Die Struktur der Sulfinsäuren (V. Mitteil. Über Polymerisationen und Polymerisationskatalysatoren) (1955)

Abstract Mit Hilfe von UV‐Spektren wird gezeigt, daβ den Sulfinsäuren in polaren und nichtpolaren Lösungsmitteln die Struktur R·SO(OH) zukommt.
Disruption of Re-replication Control by Overexpression of Human ORC1 in Fission Yeast (1996)

Initiation of DNA replication in Saccharomyces cerevisiae requires the binding of the origin recognition complex (ORC) to autonomously replicating sequences. HsORC1, a recently identified human protein related to yeast Orc1p and Cdc6p/Cdc18p, may be a component of the replication initiation complex in human cells. We have independently isolated the gene for HsORC1 and begun to address its function in eukaryotic DNA replication and its relationship to Cdc18p. Although HsORC1 failed to rescue the temperature-sensitive S. pombe cdc18-K46 strain, overexpression in a wild-type strain led to continuous DNA synthesis in the absence of mitosis. Deletion mutagenesis identified a short N-terminal region of HsORC1 that contains potential phosphorylation sites for cyclin-dependent kinase (CDK) as being sufficient to induce re-replication. In addition, we found that HsORC1 is an efficient substrate for CDKs in vitro. We propose that perturbation of the re-replication control by overexpression of HsORC1 is due to a titration of components involved in inactivating Cdc18p upon initiation of replication.
Glucose Monitoring by Means of an Intravenous Microdialysis Catheter Technique (2010)

These initial experiences are promising and motivate further research to improve the microdialysis technique. In future studies longer periods of recordings should be included to disclose technical problems.
Effect of Inlet Header Pre-Heating on the Temperature Distribution in a Steam Furnace Tube Bank (1998)

Abstract Steam furnaces encountered in chemical and power generation plants often experience a maldistribution of steam temperature at furnace tube outlets despite attempts to ensure good flow distribution in these tubes from the inlet feed header. An investigation of an existing tube bank configuration was carried out utilizing field measurements, a CFD analysis of the thermal/flow field, flow experiments with a 1:7 scale laboratory model using air as the working fluid, and a 1-D analysis of the temperature/flow distribution. The results indicate that although the inlet header does not actually run through the furnace, heat transfer by conduction from the tube walls to the inlet header wall causes preheating of the incoming steam, resulting in a substantial increase in steam temperature towards the end of the header. This steam temperature maldistribution at the inlet to the tubes persists along the tubes and manifests itself as a similar maldistribution in the tube skin wall temperatures. The latter has an impact on the system integrity if the skin wall temperature exceeds the metallurgical limit of the tube material used.
ALLOY 625 - IMPRESSIVE PASTISIGNIFICANT PRESENCEIA WESOME FUTURE (2001)

It has been close to half a century since the original research and development lead to the invention of alloy 625. Originally intended for ultra-critical steam piping, the alloy continues to find new applications and increased volume of production annually. This paper will review some of the markets where alloy 625 is the material of choice and explain the reasons for its success. Advances in material processing are noted and characterized. These advances are creating a better understanding of the uniqueness of the alloy and resulting in new uses. Welding and overlaying with alloy 625 for some developing applications will be reviewed.
Phase I Pharmacokinetic and Pharmacodynamic Study of the Oral, Small-Molecule Mitogen-Activated Protein Kinase Kinase 1/2 Inhibitor AZD6244 (ARRY-142886) in Patients With Advanced Cancers (2008)

AZD6244 was well tolerated with target inhibition demonstrated at the recommended phase II dose. PK analyses supported twice-daily dosing. Prolonged SD was seen in a variety of advanced cancers. Phase II studies are ongoing.
INTERCONVERSION AND DEGRADATION OF REDUCING SUGARS BY ANION EXCHANGE RESINS (1953)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTINTERCONVERSION AND DEGRADATION OF REDUCING SUGARS BY ANION EXCHANGE RESINSLudwig Rebenfeld and Eugene PacsuCite this: J. Am. Chem. Soc. 1953, 75, 17, 4370–4371Publication Date (Print):September 1, 1953Publication History Published online1 May 2002Published inissue 1 September 1953https://pubs.acs.org/doi/10.1021/ja01113a538https://doi.org/10.1021/ja01113a538research-articleACS PublicationsRequest reuse permissionsArticle Views71Altmetric-Citations14LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Hypoglycemic quaternary azolylpyridinium salts. Inactive analogs (1969)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTHypoglycemic quaternary azolylpyridinium salts. Inactive analogsVictor J. Bauer, Gretchen E. Wiegand, William J. Fanshawe, and Sidney R. SafirCite this: J. Med. Chem. 1969, 12, 5, 944–945Publication Date (Print):September 1, 1969Publication History Published online1 May 2002Published inissue 1 September 1969https://doi.org/10.1021/jm00305a067RIGHTS & PERMISSIONSArticle Views80Altmetric-Citations8LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (287 KB) Get e-Alerts Get e-Alerts
Effect of graphitic inclusions on the optical gap of tetrahedral amorphous carbon films (2001)

High sp3 fraction tetrahedral amorphous carbon (ta-C) films can be prepared using the filtered cathodic vacuum arc (FCVA). A by-product of the deposition process are small micrometer sized graphitic particles which are also incorporated into the film. The particle coverage of FCVA films is typically &lt;5%, and thus the effect of these graphite inclusions have been largely ignored in earlier optical gap measurements of ta-C. By incorporating a better filter design (e.g., S-bend filter), the particle coverage can be reduced to 0.1%. In this article, we show that the effect of these graphitic inclusions is to scatter or absorb light which significantly affects the optical gap measurement and hence reduces the “apparent” optical gap of the ta-C film. By comparing two ta-C films with different particle coverage but the same sp3 content of 85%, we show that we can correct for the effect of these inclusions. Our results confirm that the E04 gap of a 85% sp3ta-C matrix is 3.6 eV. The importance of considering these micro particles is emphasized as we find that for every 1% of area covered by particles, there is a 3–4 fold percentage difference between the corrected optical gap and measured gap of the film.
Ionization potentials of small carbon clusters (1993)

Ionization potentials (IP’s) of small carbon clusters (Cn, n=3–6) have been bracketed with an uncertainty of a few tenths of an eV by charge-transfer methods in a Fourier transform ion cyclotron resonance mass spectrometer. Values obtained are compared to previously determined experimental and theoretical values. Several interesting reactions other than charge-transfer were observed between the carbon cluster ions and the charge-transfer reference compounds. The products of these reactions are reported and discussed.
ChemInform Abstract: ACYLATION OF 4,6‐DIAMINO‐2‐MERCAPTOPYRIMIDINE AND ITS SALTS BY CARBOXYLIC ACID CHLORIDES (1981)

Abstract Die Acylierung von 4,6‐Dia1nino‐2‐mercapto‐pyrimidin (I) und seiner Alkalisalze mit den Säurechloriden (II) wird untersucht, wobei die Derivate (III) bis (V) gebildet werden können.
Algorithms and Hardness for Robust Subspace Recovery (2012)

We consider a fundamental problem in unsupervised learning called \emph{subspace recovery}: given a collection of $m$ points in $\mathbb{R}^n$, if many but not necessarily all of these points are contained in a $d$-dimensional subspace $T$ can we find it? The points contained in $T$ are called {\em inliers} and the remaining points are {\em outliers}. This problem has received considerable attention in computer science and in statistics. Yet efficient algorithms from computer science are not robust to {\em adversarial} outliers, and the estimators from robust statistics are hard to compute in high dimensions. Are there algorithms for subspace recovery that are both robust to outliers and efficient? We give an algorithm that finds $T$ when it contains more than a $\frac{d}{n}$ fraction of the points. Hence, for say $d = n/2$ this estimator is both easy to compute and well-behaved when there are a constant fraction of outliers. We prove that it is Small Set Expansion hard to find $T$ when the fraction of errors is any larger, thus giving evidence that our estimator is an {\em optimal} compromise between efficiency and robustness. As it turns out, this basic problem has a surprising number of connections to other areas including small set expansion, matroid theory and functional analysis that we make use of here.
Characteristics of a Phosphatidylinositol Exchange Activity of Soybean Microsomes (1987)

Microsome fractions from hypocotyls of dark-grown soybean (Glycine max [L.] Merrill) seedlings incorporated myo-inositol into phosphatidylinositol by an exchange reaction stimulated by Mn(2+) (optimum at 10 mm) and cytidine nucleotides (CMP = CDP approximately CTP) but not by Mg(2+) or nucleotides other than cytidine nucleotides. The activity was membrane associated, with an optimum pH of 8, stimulated by auxin, and inhibited by certain thiol reagents or by heating above 40 degrees C. With radioactive inositol, phosphatidylinositol was the only radioactive product. That turnover was by myo-inositol exchange was verified from experiments where unlabeled inositol replaced already incorporated inositol with approximately the same kinetics as for the incorporation of label. Both the incorporation and the displacement reactions were stimulated by Mn(2+) and CMP and both were responsive to auxin with comparable dose dependency. Corresponding exchange activities with choline or ethanolamine were not observed. The phosphatidylinositol-myo-inositol exchange activity was low or absent from plasma membrane, tonoplast, and mitochondria enriched fractions. The activity co-localized on free-flow electrophoresis and aqueous two-phase partition with NADPH cytochrome c reductase and latent IDPase, markers for endoplasmic reticulum and Golgi apparatus, respectively. With microsomes incubated with both ATP and inositol, polyphosphoinositides were unlabeled demonstrating separate locations for the inositol exchange and phosphatidylinositol kinase reactions. Thus, the auxin-responsive inositol turnover activity of soybean membranes is distinct from the usual de novo biosynthetic pathway. It is not the result of a traditional D-type phospholipase and appears not to involve plasma membrane-associated polyphosphoinositide metabolism. It most closely resembles previously described phosphatidylinositol-myo-inositol exchange activities of plant and animal endoplasmic reticulum.
Underlying quality dimensions of modern telephone connections (2006)

It is the aim of the present paper to analyze the perceptual quality dimensions of modern telephone connections. Such connections differ from standard connections in their timevariant characteristics (e.g., due to Voice-over-IP transmission or due to noise reduction algorithms) and their user interfaces (e.g., hands-free terminals). With the help of two independent auditory experiments with subsequent multidimensional analyses, three perceptual dimensions were identified for a diverse set of stimuli. These dimensions were labeled “directness/frequency content”, “continuity”, and “noisiness”. Overall listening quality scores were collected in a separate experiment. A mapping of the obtained dimensions onto the overall listening quality scores by means of a linear model revealed that “continuity” appears to be the most important dimension in terms of overall listening quality. Index Terms: assessment and modeling of speech quality, quality dimensions, multidimensional analyses
Degradation of PrP<sup>Sc</sup>by Keratinolytic Protease from<i>Nocardiopsis</i>sp. TOA-1 (2006)

A keratinolytic alkaline proteae (NAPase) from Nocardiopsis sp. TOA-1 degraded a scrapie prion without any chemical or physical treatment. Optimal temperature and pH were 60 degrees C and above pH 10.0. The scrapie prion was completely degraded within 3 min under optimal conditions.
Analysis of<i>Moraxella catarrhalis</i>by DNA Typing: Evidence for a Distinct Subpopulation Associated with Virulence Traits (2000)

Two DNA typing methods, probe-generated restriction fragment length polymorphism analysis and single-adapter amplified fragment length polymorphism analysis, were used to study the genetic relationships among 90 Moraxella catarrhalis strains. Both methods were found to be highly concordant, generating a dendrogram with 2 main branches. The division of the M. catarrhalis population into 2 subspecies was supported by analysis of the 16S rRNA sequences. Both beta-lactamase-positive and beta-lactamase-negative strains were found in all main branches, suggesting horizontal transfer of the beta-lactamase gene. In contrast, 2 virulence traits, complement resistance and adherence to epithelial cells, were strongly associated with 1 of the 2 subspecies. The branch depth suggested that complement-resistant adherent strains diverged from a common ancestor more recently than did complement-sensitive nonadherent strains. These findings suggest the existence of subpopulations of M. catarrhalis that differ in virulence, and they may have implications for vaccine development.
Head Pose and Movement Analysis as an Indicator of Depression (2013)

Depression is a common and disabling mental health disorder, which impacts not only on the sufferer but also their families, friends and the economy overall. Our ultimate aim is to develop an automatic objective affective sensing system that supports clinicians in their diagnosis and monitoring of clinical depression. Here, we analyse the performance of head pose and movement features extracted from face videos using a 3D face model projected on a 2D Active Appearance Model (AAM). In a binary classification task (depressed vs. non-depressed), we modelled low-level and statistical functional features for an SVM classifier using real-world clinically validated data. Although the head pose and movement would be used as a complementary cue in detecting depression in practice, their recognition rate was impressive on its own, giving 71.2% on average, which illustrates that head pose and movement hold effective cues in diagnosing depression. When expressing positive and negative emotions, recognising depression using positive emotions was more accurate than using negative emotions. We conclude that positive emotions are expressed less in depressed subjects at all times, and that negative emotions have less discriminatory power than positive emotions in detecting depression. Analysing the functional features statistically illustrates several behaviour patterns for depressed subjects: (1) slower head movements, (2) less change of head position, (3) longer duration of looking to the right, (4) longer duration of looking down, which may indicate fatigue and eye contact avoidance. We conclude that head movements are significantly different between depressed patients and healthy subjects, and could be used as a complementary cue.
Solifenacin for Overactive Bladder: Patient-Reported Outcomes from a Large Placebo-Controlled Trial (2009)

Objective: Overactive bladder (OAB) is a prevalent, chronic condition that can negatively affect health-related quality of life (HRQL). Treatment goals are to improve symptoms and HRQL. We assessed the efficacy of solifenacin in OAB patients using several patient-reported outcome (PRO) measures, with a focus on urgency severity. Results for the primary endpoint, reductions in daily urgency episodes, and other bladder-diary variables have been recently reported. Materials and Methods: In this 12-week multicenter trial, 739 patients (aged ⩾ 18 years) were randomized to flexibly dosed solifenacin (5/10 mg) or placebo. Prespecified secondary PRO measures included the Indevus Urgency Severity Scale (IUSS), Urgency Perception Scale (UPS), Patient Perception of Bladder Condition (PPBC), and Overactive Bladder Questionnaire (OAB-q). Appropriate statistical tests compared treatment-group differences in continuous and categorical data. Results: In the full analysis set, patients who received solifenacin (n = 357) versus placebo (n = 350) showed significant improvements on the IUSS and UPS; treatment-group differences were 0.4 (P < 0.0001) and 0.2 (P = 0.0018), respectively. On the PPBC, significantly more patients taking solifenacin (66%) than placebo (48%) perceived fewer bladder-related problems (P < 0.0001) by week 12. On the OAB-q, solifenacin was superior to placebo for the Symptom Bother and total HRQL scales and for 3 of the 4 HRQL domains at study end (P < 0.01). Overall, these findings were consistent with those reported previously for bladder-diary-documented urgency and other OAB symptoms. Conclusion: Flexibly dosed, once-daily solifenacin was associated with statistically significant and clinically meaningful improvements in urgency and other symptom-specific bother and HRQL compared with placebo.