gebhart/patrepeval huggingface dataset:
The hydrogeochemical dynamics of mine pit lakes (2002)

Abstract On cessation of mining open pits or opencast workings that extend below the water table are likely to fill with water and thus develop a mine pit lake (MPL). This body of water remains as a permanent feature on the mine site and as such becomes a closure issue with respect to water quality and potential to degrade groundwater. Further, it may present a risk to the environment through the development of poor quality water with elevated concentrations of metals, metalloids, sulphate and depressed pH. The prediction of future pit lake water quality within a MPL is, therefore, essential in considering environmental impact on a closed or abandoned mine facility. The controls on a MPL will vary over time, and will involve chemical, biological and physical processes. Localized and regional-scale processes affect these in turn. Consequently, in order to predict pit lake water quality it is essential to understand the hydrogeological, geochemical and limnological processes that influence water quality.
Stimulation of Root Initiation from Cultured Rose Shoots through the Use of Reduced Concentrations of Mineral Salts1 (1982)

Abstract In vitro -derived shoots of ‘Improved Blaze’ rose ( Rosa hybrida L.) were used to investigate the cause of improved root initiation obtained by lowering the concentration of the Murashige and Skoog (MS) salt formulation in the nutrient medium. The number and length of roots per explant increased as the concentration of total nitrogen in the MS salt formulation was reduced from 60 to 7.5 m m . There was no effect on rooting with as much as a 16-fold reduction in the concentration of the remaining MS salts from that of the normal MS formulation, when total nitrogen was kept at a constant 7.5 m m . When nitrogen was maintained at 7.5 m m and the concentrations of the remaining salts were maintained at 1/2 times that of the MS salt formulation, rooting was unaffected by raising the total solute concentration with NaCl to that when the medium contained the full MS nitrogen salt complement. These results show that lowering the total mineral salt level in the nutrient medium provides a more favorable nitrogen salts concentration for rhizogenesis than that provided by the MS salt formulation.
Fracture Properties of Multirecycled Asphalt Mixes from Four-Point Bending Test Using Digital Image Correlation and Back Calculation (2019)

ABSTRACT Six different asphalt mixes were subjected to the four-point bending fracture tests designed at the University of Lyon/École Nationale des Travaux Publics de l’État (ENTPE). Among the six tested mixes, three were hot mixes and three were produced according to a warm process with foamed binder. For each of the two processes, the first mix contained 0 % reclaimed asphalt pavement (RAP). The second mix contained 40 % RAP from a milling process. The third mixes contained 40 % of the second mix, aged artificially in the lab and recycled. Two methods were applied to determine the crack propagation during fracture testing. The first one, called the displacement ratio method for predicting crack length, is based on displacements measurements. The second one used digital image correlation and strain field analysis. The two methods gave similar results for crack length values during the tests. The stress intensity factor (KIC) as a function of crack length was calculated. Results showed rather close fracture properties for the six mix types.
Safety and Immunological Outcomes Following Human Inoculation With Nontypeable Haemophilus influenzae (2013)

The statistical design incorporated a slow escalation to higher dose levels. HCD50 and HCD90 Bayesian estimates were identified as approximately 2000 and 150 000 colony-forming units, respectively; credible interval estimates were broad. This study provides a potential platform for early proof of concept studies for NTHi vaccines, as well as a way to evaluate bacterial factors associated with colonization.
Spatial Distribution of Di- and Tri-methyl Lysine 36 of Histone H3 at Active Genes (2005)

Methylation of lysine 4 of histone H3 (K4/H3) is linked to transcriptional activity, whereas methylation of K9/H3 is tightly associated with gene inactivity. These are well characterized sites of methylation within histones, but there are numerous other, less characterized, sites of modification. In Saccharomyces cerevisiae, methylation of K36/H3 has been linked to active genes, but little is known about this methylation in higher eukaryotes. Here we analyzed for the first time the levels and spatial distribution of di- and tri-methyl (di- and tri-Me) K36/H3 in metazoan genes. We analyzed chicken genes that are developmentally regulated, constitutively active, or inactive. We found that active genes contain high levels of these modifications compared with inactive genes. Furthermore, in actively transcribed regions the levels of di- and tri-Me K36/H3 peak toward the 3' end of the gene. This is in striking contrast to the distributions of di- and tri-Me K4/H3, which peak early in actively transcribed regions. Thus, di/tri-Me K4/H3 and di/tri-Me K36/H3 are both useful markers of active genes, but their genic distribution indicates differing roles. Our data suggest that the unique spatial distribution of di- and tri-Me K36/H3 plays a role in transcriptional termination and/or early RNA processing.
Fluorescence lifetimes and sensitization rate constants for dyes adsorbed to silver halide microcrystals (1976)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTFluorescence lifetimes and sensitization rate constants for dyes adsorbed to silver halide microcrystalsAnnabel A. MuenterCite this: J. Phys. Chem. 1976, 80, 20, 2178–2183Publication Date (Print):September 1, 1976Publication History Published online1 May 2002Published inissue 1 September 1976https://pubs.acs.org/doi/10.1021/j100561a009https://doi.org/10.1021/j100561a009research-articleACS PublicationsRequest reuse permissionsArticle Views119Altmetric-Citations33LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Design and Evaluation of a Breath-Analysis System for Biological Monitoring of Volatile Compounds (2001)

To ensure the health and safety of workers, integrated industrial hygiene methodologies often include biological monitoring of the workers to help understand their exposure to chemicals. To this end, a field-portable breath-analysis system was developed and tested to measure selected solvents in exhaled air. The exhaled breath data were evaluated using a physiologically based pharmacokinetic (PBPK) model to relate exposure to tissue dose. The system was designed to monitor workers every time they entered or left a work environment--a vast improvement over current 8-hour integrated monitoring strategies. The system combines (1) chemical dosimeters to measure airborne contaminant levels (analyzed in the field/ workplace); (2) real-time breath analysis to quantitate exposure; and 3) PBPK models to estimate internal target tissue dose. To evaluate the system, field tests were conducted at two locations: (1) at an incinerator in Tennessee monitoring benzene and toluene exposures; and (2) a waste repackaging facility in Washington State where hexane, trimethylbenzene, and methylene chloride was monitored. Exhaled breath was sampled and analyzed before and after each specific job task, which ranged from 15 min to 8 hours in duration. In both field studies several volunteers had posttask breath levels higher than pretask levels. The greatest increase corresponded to 573 ppb for methylene chloride and 60 ppb for toluene. Compared with breath analysis, the chemical dosimeters underpredicted the dosimetry, particularly for longer sampling intervals when the volume of air sampled may have diluted exposures. The results of the field studies illustrate the utility of monitoring workers for exposures throughout the day, particularly when job-specific tasks may indicate a potential for exposure.
Multiview structure from motion in trajectory space (2011)

Most nonrigid objects exhibit temporal regularities in their deformations. Recently it was proposed that these regularities can be parameterized by assuming that the nonrigid structure lies in a small dimensional trajectory space. In this paper, we propose a factorization approach for 3D reconstruction from multiple static cameras under the compact trajectory subspace representation. Proposed factorization is analogous to rank-3 factorization of rigid structure from motion problem, in transformed space. The benefit of our approach is that the 3D trajectory basis can be directly learned from the image observations. This also allows us to impute missing observations and denoise tracking errors without explicit estimation of the 3D structure. In contrast to standard triangulation based methods which require points to be visible in at least two cameras, our approach can reconstruct points, which remain occluded even in all the cameras for quite a long time. This makes our solution especially suitable for occlusion handling in motion capture systems. We demonstrate robustness of our method on challenging real and synthetic scenarios.
One billion years of p53/p63/p73 evolution (2009)

Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans the biological, physical, and social sciences.
Therapeutic Guidelines for Atopic Dermatitis 2002 (2005)

We summarized the Therapeutic Guidelines for Atopic Dermatitis 2002, and outlined important points with reference to medical care and management of atopic dermatitis.
Gut-mediated hypercalcemia in rabbits bearing VX2 carcinoma: new mechanism for tumor-induced hypercalcemia. (1982)

The VX2 carcinoma-bearing rabbit is an animal model for tumor-induced hypercalcemia, thought to be due to increased bone destruction effected by prostaglandin E2. The present experiments suggest that the pathophysiology of the hypercalcemia differs from that previously proposed. Tumor was transplanted intramuscularly into 2.5- to 3-kg male New Zealand White rabbits, which were conditioned to a 1.5% calcium diet and treated with daily subcutaneous injections of dichloromethane diphosphonate (10 mg . kg-1 . day-1), a potent inhibitor of bone resorption, or 0.9% NaCl (2 ml . kg-1 . day -1). The diphosphonate had no significant effect on plasma Ca2+ in either group. After day 31, half the animals of each group were fed a calcium-free diet. This normalized the plasma Ca2+ in each VX2-bearing rabbit within 3 to 4 days but had little effect in control rabbits. In a second series of experiments, VX2-bearing rabbits maintained on standard rabbit chow were treated for 11 days with parenteral indomethacin (30--60 mg/day) or 0.9% NaCl. Although indomethacin normalized the markedly elevated urinary excretion of prostaglandin E2, both treatment groups became severely hypercalcemic. Dietary calcium restriction promptly restored to normal the plasma Ca2+ concentration. In a third series of experiments, rabbits were fed standard rabbit chow and treated with oral indomethacin (40 mg/day) while control-rabbits were pair fed in identical chow. Transplantation of VX2 tumor into both groups caused hypercalcemia. We conclude that the hypercalcemia produced by this tumor strain is indomethacin resistant and dependent on an increase in gastrointestinal calcium absorption, not on skeletal calcium mobilization.
Automated Solid‐Phase Synthesis and Structural Investigation of <i>β</i>‐Peptidosulfonamides and <i>β</i>‐Peptidosulfonamide/<i>β</i>‐Peptide Hybrids: <i>β</i>‐Peptidosulfonamide and <i>β</i>‐Peptide Foldamers are Two of a Different Kind (2002)

Abstract Fmoc‐protected β ‐aminoethane sulfonylchlorides can be employed for efficient automated solid phase synthesis of β ‐peptidosulfonamides and β ‐peptidosulfonamide/ β ‐peptide hybrids containing one or more β ‐peptidosulfonamide residues. Thus, Fmoc‐protected β ‐aminoethane sulfonylchlorides 5a – c led to the hexa‐ β ‐peptidosulfonamide 9 and the nona‐ β ‐peptidosulfonamide 10 . In addition, the β ‐peptidosulfonamide/ β ‐peptide hybrids 13 and 16 , consisting of six and nine β ‐residues, respectively, and containing a single β ‐peptidosulfonamide unit in the middle, as well as the peptidosulfonamide/ β ‐peptide hybrid 15 with nine β ‐residues, including an N‐terminal β ‐peptidosulfonamide residue, were synthesized by automated solid‐phase synthesis. Both CD and NMR spectroscopic measurements did not indicate any helical secondary structure for 9 and 10 . As was shown by CD‐measurements, the β ‐peptidosulfonamide residue in the hybrids 13, 15 , and 16 acts as a ‘helix breaker', especially when located in the middle of the hybrid chain ( 13 and 16 ), but, although to a lesser extent, also at the N‐terminus.
Model for a Common Notion of Privacy Leakage on Public Database. (2011)

Privacy is an increasingly important aspect of data publishing services. If personal private information is leaked from the data, the service will be regarded as unacceptable by the original owners of the data. Two different approaches to defining a notion of database privacy, the generalization method and the perturbation method, have been independently studied. These two approaches have significantly differences, making it hard to compare related research. In this paper, we propose a unified model that is based on the perturbation method, but which is applicable to generalized data sets. In particular, this model applies the notion of differential privacy to data sets that satisfy k-anonymity. We demonstrate this approach through a simple case study. This is a first step towards a common notion for protecting database privacy.
Advances and Challenges in the Synthesis of Poly(<i>p</i>‐phenylene vinylene)‐Based Polymers (2014)

Abstract We provide an overview of the current progress in the synthesis of poly( p ‐phenylene vinylene) (PPV) polymers. The described synthetic approaches can be divided into four main categories: polymerization of quinodimethane intermediates, metathesis polymerization, nucleophilic polycondensation, and palladium‐catalyzed cross‐coupling. While such variety is remarkable and very high‐molecular‐weight PPV can be prepared by some methods, the synthetic chemistry of PPV still limits the structural variety and purity of arylene vinylene polymers. In particular, palladium‐catalyzed cross‐coupling reactions, the method of choice in the contemporary conjugated polymer chemistry, often shows limited success in PPV series. On the other hand, the possibility of using metathesis polymerization creates new opportunities not available for other classes of conjugated polymers.
Negative differential resistances from Hg1−<i>x</i>Cd<i>x</i>Te-CdTe single quantum barrier heterostructures (1986)

A novel negative differential resistance device is proposed and analyzed theoretically. The proposed device is a Hg1−xCdxTe-CdTe-Hg1−xCdxTe single quantum barrier heterostructure with 0.2≤x≤0.4. The anticipated negative differential resistance is a consequence of the unique properties of Hg1−xCdxTe-CdTe heterojunctions. Calculations are performed to predict the current-voltage characteristics of the proposed device. The results indicate that room-temperature negative differential resistances can be obtained over a large range of applied voltages. The high-speed capabilities associated with quantum barrier tunnel structures make the proposed device a candidate for high-frequency applications.
A new approach to the estimation of the vocal tract area function (1993)

The authors present a novel method for estimating the area function of the vocal tract based on the magnitude of the Fourier transform of the speech signal and area(s) at some point(s) along the vocal tract. This method allows for incorporation of any available knowledge about the vocal tract in the solution. This iterative method is based on a combination of signal extrapolation and phase retrieval. Results obtained from synthesized speech show that the method converges to a realistic solution after a small number of iterations.< <ETX>></ETX>
Association of <i>MC1R</i> Variants and Risk of Melanoma in Melanoma-Prone Families with <i>CDKN2A</i> Mutations (2005)

Major risk factors for melanoma include many nevi, especially dysplastic nevi, fair pigmentation, freckling, poor tanning ability, and germ line mutations in the CDKN2A, CDK4, or MC1R genes. We evaluated the relationship between MC1R and melanoma risk in CDKN2A melanoma-prone families with extensive clinical and epidemiologic data. We studied 395 subjects from 16 American CDKN2A families. Major melanoma risk factors were assessed by clinical examination or questionnaire; MC1R was sequenced. Odds ratios were estimated by unconditional and conditional logistic regression models. We examined the distribution of MC1R variants and median ages at melanoma diagnosis in multiple primary melanoma (MPM) and single primary melanoma (SPM) patients. Presence of multiple MC1R variants was significantly associated with melanoma, even after adjustment for major melanoma risk factors. All 40 MPM patients had at least one MC1R variant; 65% of MPM patients versus only 17% of SPM patients had at least two MC1R variants (P < 0.0001). For all 69 melanoma patients combined, as well as the 40 MPM patients, there was a statistically significant decrease in median age at diagnosis as numbers of MC1R variants increased (P = 0.010 and P = 0.008, respectively). In contrast, no significant reduction in age at melanoma diagnosis was observed for SPM patients (P = 0.91). The current study suggests that the presence of multiple MC1R variants is associated with the development of multiple melanoma tumors in patients with CDKN2A mutations. Additional studies are needed to confirm these findings and to explore the mechanisms that may contribute to this relationship.
ChemInform Abstract: Stabilization of the Ti<sub>3</sub>Co<sub>5</sub>B<sub>2</sub>‐Type Structure for Ti<sub>3‐x</sub>Si<sub>x</sub>Ru<sub>5</sub>B<sub>2</sub> Through Si—Ti Substitution. (2015)

Abstract Ti 3‐x Si x Ru 5 B 2 (x = 0.25, 0.50, 0.75, 1.00, 1.25) phases are prepared by arc melting of the elements and characterized by single crystal XRD, magnetization and resistivity measurements, and electronic structure calculations at the TB‐LMTO‐ASA and extended Hueckel level of theory.
Assessment of Coronary Stenosis by a 16-Slice MDCT Scanner in Asymptomatic Diabetic Patients Starting Dialysis Therapy (2008)

MDCT seemed to be an effective non-invasive method of screening patients with diabetic CKD for CAD.
Partial ATP depletion induces Fas- and caspase-mediated apoptosis in MDCK cells (1999)

Brief periods of in vitro hypoxia/ischemia induce apoptosis of cultured renal epithelial cells, but the underlying mechanisms remain unknown. We show that partial ATP depletion (approximately 10-65% of control) results in a duration-dependent induction of apoptosis in Madin-Darby canine kidney (MDCK) cells, as evidenced by internucleosomal DNA cleavage (DNA laddering and in situ nick end labeling), morphological changes (cell shrinkage), and plasma membrane alterations (externalization of phosphatidylserine). The ATP-depleted cells display a significant upregulation of Fas, Fas ligand, and the Fas-associating protein with death domain (FADD). Exogenous application of stimulatory Fas monoclonal antibodies also induces apoptosis in nonischemic MDCK cells, indicating that they retain Fas-dependent pathways of programmed cell death. Furthermore, cleavage of poly(ADP)ribose polymerase (PARP) is evident after ATP depletion, indicating activation of caspases. Indeed, the apoptotic cells display a significant increase in caspase-8 (FLICE) activity. Finally, apoptosis induced by ATP depletion is ameliorated by pretreatment with inhibitors of caspase-8 (IETD), caspase-1 (YVAD), or caspase-3 (DEVD) but is not affected by inhibitors of serine proteases (TPCK). Our results indicate that partial ATP depletion of MDCK cells results in apoptosis and that Fas- and caspase-mediated pathways may play a critical role.
Capillary electrophoretic separations of proteins using nonionic surfactant coatings (1991)

Capillary zone electrophoretic separations of proteins have been achieved by using nonionic surfactant coated capillaries. Capillaries were prepared by derivatization of the silica surface with octadecylsilane followed by the deposition of a layer of nonionic surfactant from an aqueous solution above the critical micelle concentration. This coating is of sufficient thickness and hydrophilicity to reduce both protein adsorption and electroosmotic pumping. This hydrophilic coating reduces electroosmotic pumping 5-8-fold while resolving proteins quickly and efficiently with good recovery. The coating provides a stable and reproducible means of deactivation, while the rate of electroosmotic pumping stays relatively constant throughout the pH range 4-11. This allows the pH to be varied to enhance selectivity without adversely affecting the flow rate.
Behavior of Previously Frozen Erythrocytes Used during Open‐heart Surgery (1970)

Glycerolized human red blood cells that had been stored in the frozen state at ‐80 C up to six months, thawed, and washed by the dilution‐agglomeration procedure of Huggins, were administered during extracorporeal circulation along with nonfrozen acid‐citrate‐dextrose‐(ACD) stored blood. Eleven patients who received both nonfrozen ACD‐stored blood and the previously frozen, washed, concentrated cells were compared with 14 patients who were given whole blood stored only in ACD. No significant differences were observed between the two groups in respect to platelet count, partial thromboplastin time, prothrombin time, or fibrinogen level. Higher plasma and urine hemoglobin levels were observed in the patients who received both blood stored in ACD and washed, previously frozen, concentrated red blood cells. Hemoglobinuria was observed in both groups but was not accompanied by significant differences in BUN or creatinine levels. There was no significant difference in morbidity or mortality between the two groups of patients.
Optisch aktive Übergangsmetall-Komplexe, LV [1]. Darstellung und Stereochemie von [C<sub>5</sub>H<sub>5</sub>Mo(CO)<sub>2</sub> NN’]PF<sub>6</sub> mit NN’=Ethylen-diamin und Propylendiamin / Optically Active Transition Metal Complexes, LV [1]. Preparation und Stereochemistry of [C<sub>5</sub>H<sub>5</sub>Mo(CO)<sub>2</sub>NN′]PF<sub>6</sub> with NN′=Ethylenediamine and Propylene- diamine (1978)

In the reaction of C 5 H 5 Mo(CO) 3 Cl with ethylenediamine and propylenediamine, abbreviated with NN′, the square pyramidal cations [C 5 H 5 Mo(CO) 2 NN′] + are formed. The diastereoisomeric pairs of enantiomers of the propylenediamine derivative are separated by fractional crystallization. The epimerization at the asymmetric Mo atom (τ 1,2 = 30 min, 75 °C, CD 3 OD solution) can be followed by 1 H NMR spectroscopy