gebhart/patrepeval huggingface dataset:
SEGUNDO CONGRESO NACIONAL DE TRAUMATOLOGIA, CIRUGIA DE URGENCIA Y MEDICINA LEGAL (1957)

EL COMITE ORGANIZADOR, REPRESENTADO A TODOS LOS ELEMENTOS QUE FORMAN LOS SERVICIOS MEDICOS DE LA CRUZ VERDE DEL D.F., INVITA A LOS DOCTORES PARA QUE ASISTA Y PARTICIPE A LAS ACTIVIDADES QUE SE REALIZARAN DEL 7 AL 12 DE OCTUBRE, EN LAS CUALES SE REALIZARAN LABORES EN LOS QUIROFANOS EN EL NUEVO HOSPITAL DE LA CRUZ VERDE Y LAS SESIONES SE LLEVARAN A CABO EN EL AUDITORIO DE ESTE INMUEBLE.
Digital image analysis supports a nuclear‐to‐cytoplasmic ratio cutoff value below 0.7 for positive for high‐grade urothelial carcinoma and suspicious for high‐grade urothelial carcinoma in urine cytology specimens (2018)

The N:C ratios for the HGUC (0.57) and SHGUC (0.53) categories are lower than those previously suggested in TPS. The authors advocate reducing the N:C ratio below the current threshold of 0.7.
[Anti-inflammatory and analgesic activities of N-deacetyllappaconitine and lappaconitine]. (1987)

N-deacetyllappaconitine (DLA) 1—10 mg/kg or lappaconitine (LA) 1—6 mg/kg inhibited several inflammatory processes, such as increase of capillary permeability due to ip 0.7% acetic acid l0 mg/kg in mice； ear swelling induced by xylene in mice； edema produced by injecting 1% carrageenin 0.15 ml or fresh egg white 0.l ml beneath the planter surface of hind paw in rats and the growth of rat granuloma caused by cotton pellets, without influencing the weights of thymus and adrenal. Their anti-inflammatory activity was also demonstrated in adrenalectomized rats. DLA and LA neither prolonged the surviving time of adrenalectomized rats nor reduced the content of adrenal ascorbic acid in rats. These results suggest that the anti-inflammatory actions of DLA and LA do not depend on stimulation of the pituitary-adrenal axis.
 The hot plate, formaldehyde and HAc-writhing tests in mice showed that DLA and LA had a marked analgesic action, their sc median analgesic doses (ED50) were 7.1, 3.8 mg/kg and 2.3, 3.5 mg/kg in mice with formaldehyde and HAc-writhing test, respectively.
 DLA exhibited marked local anesthetic activity as shown by sciatic nerve block in mice, its ED50 concentration was 0.076%.
 DLA 15 mg/kg and LA 6 mg/kg ip showed an antipyretic effect in rats with fever induced by sc injection of 7% yeast 3 ml/kg.
 The ip LD50 of DLA and LA were 23.5, 10.5 mg/kg (mice) and 29.9, 9.9 mg/kg (rats), respectively.
Electric-field changes and the design of lightning-flash counters (1960)

Examples of electric-field and field-change records of lightning discharges will be discussed in relation to the design of lightning-flash counters. Correlations between stroke counts and visual observations of nocturnal lightning were found to be very poor for a stroke counter that operates on the abrupt-field-change principle. The abrupt field changes of both signs that accompany all lightning discharges make it virtually impossible to discriminate between ground and cloud flashes with stroke counters of the conventional type. A reliable total count for nocturnal lightning of both types can be obtained with a photomultiplier tube. A photomultiplier operated in coincidence with an electric-field-change meter can be utilized to discriminate against sferics and man-made interference. Conversely, if the photomultiplier and field-change meter are operated in anticoincidence, a trigger system can be constructed which will accept only sferics that originate from outside the area of visible lightning discharges.
Polarization-maintaining large-mode-area photonic crystal fibres with solid microstructured cores (2007)

A novel polarization-maintaining large-mode-area photonic crystal fibre is proposed. Birefringence in the fibre is introduced by a solid microstructured core with two-fold symmetry. Numerical investigation indicates that one such fibre shows an almost constant birefringence of 1.8 × 10−4 over a wide wavelength range and mode areas of 145.8 and 152.6 µm2 at the wavelength of 1.55 µm, for x- and y-polarized states, respectively.
Inhibition of rat colon tumor isograft growth with dequalinium chloride (1986)

• In searching for a new approach to the systemic treatment of colorectal carcinoma, we have observed that certain lipophilic cationic compounds are accumulated and retained for a significantly longer period in the mitochondria of living carcinoma cells than in normal cells or sarcoma cells. We report the in vivo therapeutic effect of one of these compounds, dequalinium chloride, on the W163 rat colon carcinoma isograft, which grows rapidly in Wistar/Furth rats after primary tumor implantation, and which recurs rapidly after primary tumor resection. In the primary transplant model, tumors were implanted, and daily dequalinium chloride treatments were begun the following day in doses ranging from 1 to 10 mg/kg. In the recurrence model, isografts were implanted, allowed to grow for one week, and then all gross tumor was resected. Dequalinium chloride was administered in varying daily doses starting the day after resection. In both models, tumor was removed on day 11 after implantation or resection. At sublethal doses, dequalinium chloride significantly inhibited primary tumor growth to 60% that of controls and recurrent tumor growth to 50% that of controls. We propose that this unique biologic approach of targeting carcinoma mitochondria with lipophilic cationic compounds may provide a major new opportunity for treating colorectal carcinoma. (<i>Arch Surg</i>1986;121:1272-1275)
A Heat and Mass Transfer Model for the Simulation of the Wet Limestone Flue Gas Scrubbing Process (1998)

The efficiency of a limestone flue gas scrubber depends on such a large number of coupled parameters that their influence on the absorption cannot be sufficiently investigated using only experimental measurements in pilot or full-scale plants. A systematic and cost-effective optimization of the highly developed technology used today is only possible with the support of a simulation model that is based on fundamental scientific and engineering principles containing a small number of physically well-defined parameters.
Back-attack Phenomena of Gas Jets with Submerged Horizontally Blowing and Effects on Erosion and Wear of Refractory Lining. (1999)

Taken the refining process in an 18 t AOD vessel for example, the "back-attack" phenomena of the horizontal rotating and non-rotating gas jets and their effects on the erosion and wear of the refractory lining were investigated in a water model. For this refining process, the two-tuyere (lance with constant cross-sectional area) blowing of gas is operated using the annular-tube type tuyere. The geometric similarity ratio of the model unit (including the tuyere) with its prototype was 1/3. The relations of the gas blowing rate, blowing pressure, angular separation between the two tuyeres, type of tuyere and other operation parameters with the back-attack action of the gas jet and the refractory lining erosion and wear were examined under the different operating modes. The appropriate back-attack frequencies and pressures were continuously monitored and measured by means of a dynamic resistance strain-meter of YD-21 type with an anti-water pressure sensor made specially. A light-beam oscilloscope of SC16A type recorded simultaneously the back-attack waves. Also, the modeling experiment on the erosion and wear of the refractory lining was carried out. The results indicated that the back-attack phenomena of the horizontal rotating and non-rotating gas jets have respectively the different features from that in a bottom blowing. On the back-attack phenomena of these two kinds of jets, the gas streams of the inner tubes (main-tuyeres) have all a governing bearing, and the annular slit pipe (sub-tuyere) streams show an evident alleviation and suppression effect. The circulative motion of the liquid in the bath would be another important reason to bring about the back-attack phenomenon of a submerged gas jet. The buoyancy force gives a considerable influence; it is able not only to increase the back-attack intensity of a horizontal gas jet, but also to enlarge the locally eroded and worn zone of the refractory lining. The influence of the tuyere position (the angle included between the two tuyeres) is not so remarkable in the conditions of the present work. The rotating motion of a horizontal gas jet may decrease the frequency and intensity of the back-attack action and reduce the eroded and worn rate and area of the refractory lining under a same blowing pressure. The annular-spiral tube type tuyere with a reasonable structure may be expected to have a good latent using power and composite effectiveness.
TRANSFORMATION KINETICS OF PLUTONIUM (1958)

The transformation kinetics of the alpha, beta, gamma, and delta phases of plutonium were determined using density measurements. Isothermal reaction curves of metastable beta, gamma, and delta were obtained and the time- temperature-transformation curves were sketched. The rate of transformation of alpha in the beta temperature range was determined. The temperature of the maximum rate of transformation of beta was betwcen 0 and --20 deg C. The reaction was quite sluggish above 80 deg C. Increasing the amount of normal impurities decrcases the rate of transformation and shifts the T-T-T- curves to the right. (auth)
Cell-free DNA from human plasma and serum differs in content of telomeric sequences and its ability to promote immune response (2017)

Circulating cell-free DNA (cfDNA) may be involved in immune response regulation. We studied the variations in abundance of telomeric sequences in plasma and serum in young healthy volunteers and the ability of cfDNA contained in these samples to co-activate the TNF-α m RNA expression in monocytes. We performed qPCR to determine relative telomere length (T/S ratios) in plasma, serum and whole blood of 36 volunteers. Using paired samples of plasma and serum and DNase treatment, we analysed the contribution of cfDNA to the co-activation of TNF-α mRNA expression in THP1 monocytic cell line. We found significant differences between paired plasma and serum samples in relative T/S ratios (median 1.38 ± 1.1 vs. 0.86 ± 0.25, respectively) and in total amounts of cfDNA and in estimated total amounts of telomeres which were significantly higher in serum than in plasma. TNF-α mRNA expression in THP1 cells increased significantly after DNase treatment of all samples used for stimulation. The highest TNF-α mRNA expressions were observed after stimulation with DNase treated serum samples. Our results suggest that the different content of telomeric sequences in plasma and serum may contribute to the tuning of immune response. Further studies of this interesting phenomenon are needed.
REACTION OF NITROGEN WITH NIOBIUM (1959)

Reaction rates of niobium with nitrogen were determined gravimetrically from 675. to 875 deg C with a recording microbalance and volumetrically from 1100 to 1600 deg C with a modified Sieverts apparatus. Diffusion coefficients and terminal solubilities were determined from 800 to 1600 deg C by the concentration- gradient technique. Tne reaction of nitrogen with niobium follows a parabolic rate law at 675 to 1600 deg C. The expression for the diffusion coefficient for nitrogen in niobium at 800 to 1600 deg C is given as well as the expression for the terminal solubility for nitrogen in niobium. (auth)
Transforming Growth Factor-α Stimulates Proto-Oncogene c- <i>jun</i> Expression and a Mitogenic Program in Primary Cultures of Adult Rat Hepatocytes (1989)

Human transforming growth factor-alpha (TGF-alpha, MW 5547) initiates a mitogenic program in "quiescent" 11-to 13-day-old primary cultures of adult rat hepatocytes. Using validated growth reinitiation assays and chemically defined conditions (Koch and Leffert, 1979a) that simulate proto-oncogene expression in regenerating liver (Kruijer et al., 1986), we find that 5.4 nM TGF-alpha stimulates: (i) increases in rates of amiloride-sensitive 22Na+ uptake; (ii) a transient induction in steady-state mRNA levels of proto-oncogene c-jun; (iii) specific increases in hepatocyte nuclear [3H]dT labeling indices, augmented synergistically by insulin and glucagon; and (iv) increases in rates of S-phase entry. Comparative studies indicate that TGF-alpha is a more effective hepatocyte growth promoter than mouse epidermal growth factor. These observations, and published reports linking normal and cancerous liver as biosynthetic sources of TGF-alpha, suggest an autocrine or paracrine role for TGF-alpha in the control of hepatic growth, regeneration, and gene expression.
Using PDMS Micro-Transfer Moulding for Polymer Flip Chip Packaging on MEMS (2005)

Polymer flip chip process utilizes Ag filled thermoset and/or thermoplastic polymers, in combination with stencil printing processes to form polymer bump interconnects of flip chip IC devices (Estes, 1998). Nevertheless, slumping behavior of conventional polymer interconnect material during bumping process on the wafer chip has constrained the bump height achieved by the most common stencil printing to 50mum (Kulesza et al., 1997). A bumping process to form fine pitch, high aspect ratio polymer flip chip bumps without slumping was developed by producing a through-hole PDMS micro-transfer mould on a metallized wafer (Wong, et al., 2003). In this paper, a MEMS chip (Lee, et al., 2003) was packaged by the PDMS micro-transfer mould technique to evaluate the performance of the interconnection method. Flip chip assembly process was then performed on the printed circuit board (PCB) and some functionality tests was conducted afterwards. The designed dimension of the polymer bump is 150mum in diameter, 90mum in height, and at a 245mum pitch. Bump adhesion force was measured and found to be about 40gram. Electrical conductivity test was also conducted after PCB assembly as preliminary reliability test of the whole assembly process. Results showed that the MEMS chip was functioning well with new polymer bumping method. With this bumping approach, intrinsic slumping problem of the conductive polymer paste is resolved. This low temperature fabrication technique is an important development for MEMS packaging
DCAF4L2 promotes colorectal cancer invasion and metastasis via mediating degradation of NFκb negative regulator PPM1B. (2016)

DCAF4L2 is a member of WD-repeat proteins, which commonly serve as mediators of protein-protein interplay. In this study, we reported that elevated DCAF4L2 expression in human colorectal cancer (CRC) significantly correlated with a more advanced clinical stage as in lymphatic and distant metastasis. More importantly, elevated DCAF4L2 expression is an independent prognosis factor for survival. Genetic perturbations demonstrated that DCAF4L2 overexpression in CRC cells promoted cell migration and invasion, whereas knockdown of which had opposing effects. Moreover we discovered that DCAF4L2 overexpression could promote epithelial-mesenchymal-transition (EMT) through activating NFκB signal pathway. Mass spectrometry analysis showed that DCAF4L2 could form an E3 ligase complex with Cul4A and DDB1 thus mediated degradation of PPM1B, which has been reported to negatively regulate NFκB signaling. We identified PPM1B as a substrate of Cul4A-DDB1-DCAF4L2 E3 ligase complex, as knockdown of PPM1B abrogated shDCAF4L2 mediated inhibition of cell invasion in CRC cells. For further verification, DCAF4L2 expression inversely correlated with PPM1B expression in a cohort of 87 CRC patients. These findings may provide insight into the understanding of DCAF4L2 as a novel critical factor and a candidate target for CRC treatment.
A new diamond search algorithm for fast block matching motion estimation (2002)

Based on the analysis of certain existing fast block matching algorithms (BMAs) and study of motion vector distributions of real-world image sequences, a new diamond search (DS) algorithm for fast block matching motion estimation is proposed in this paper. Simulation results demonstrate that the proposed DS algorithm greatly outperforms the well-known three-step search (TSS) algorithm. Compared with the new three-step search (NTSS) algorithm, the DS algorithm achieves similar performance but requires approximate 20%-25% less computation. Compared with some recently proposed fast BMAs, such as the four-step search (4SS) and the block-based gradient descent search (BBGDS), our DS algorithm also shows its superiority.
Radiographic changes in acute exacerbations of cystic fibrosis in adults: a pilot study. (1994)

The 14 specific radiographic findings studied, including peribronchial thickening, mucous plugs, air-space disease, and fluid levels, were not useful in determining whether an adult patient with cystic fibrosis was having acute exacerbation of the disease. With regard to these individual variables, chest radiographs are not helpful in the management of acute exacerbation of cystic fibrosis in adults. However, overall change approached statistical significance (p = .06). The value of chest radiography lies more in excluding the rare major complication, such as pneumothorax, than in diagnosing the usual exacerbation.
Plerixafor, a CXCR4 antagonist for the mobilization of hematopoietic stem cells (2008)

Stem cells harvested from peripheral blood are the most commonly used graft source in hematopoietic stem cell transplantation. While G-CSF is the most frequently used agent for stem cell mobilization, the use of G-CSF alone results in suboptimal stem cell yields in a significant proportion of patients undergoing autologous transplantation. Plerixafor (AMD3100, Genzyme Corporation) is a bicyclam molecule that antagonizes the binding of the chemokine stromal cell-derived factor-1 (SDF-1) to its cognate receptor CXCR4. Plerixafor results in the rapid and reversible mobilization of hematopoietic stem cells into the peripheral circulation and is synergistic when combined with G-CSF. In clinical studies of autologous stem cell transplantation, the combination of plerixafor and G-CSF allows the collection of large numbers of stem cells in fewer apheresis sessions and can salvage those who fail G-CSF mobilization alone.
A novel approach to the ultrastructural localization of cell surface receptors: affinity-gold labeling of Na, K-ATPase. (1988)

We describe here a novel method of affinity-gold labeling for the ultrastructural localization and biochemical characterization of functional cell surface receptors. This approach combines the widely used colloidal gold technique, a previously published method for coating the gold with a matrix of derivatized dextran, small receptor-specific ligands, and a photoactivatable cross-linker. The resulting gold-affinity probe directed to a selected receptor by the ligand, is subsequently attached to the receptor by light activation of the cross-linker. As a specific example, a gold affinity probe prepared with ouabain, a selective inhibitor of Na,K-ATPase, as the directing ligand was used to investigate the ultrastructural localization of this enzyme complex in cell membranes. The biological activity of ouabain covalently linked to derivatized dextran containing the photoactivatable cross-linker was examined by its action on ion transport across dog trachea epithelium and on the enzyme activity of Na,K-ATPase preparations obtained from the rectal gland of the elasmobranch, Mustelus californicus. By these tests the probe mimics the effects of free ouabain. Electron micrographs of labeled human erythrocytes and cultured human foreskin fibroblasts showed an apparent random distribution of Na,K-ATPase on the plasma membranes of these cells. Binding of the probe was blocked in the presence of excess ouabain, a result demonstrating that the affinity probe binds at the same sites as free ouabain. Covalent attachment of probe by light activation of the nitroarylazido groups greatly enhanced retention during washing and standard procedures of fixation and dehydration. The high density of the gold probe was utilized to isolate the covalently attached membrane components from labeled human foreskin fibroblasts.(ABSTRACT TRUNCATED AT 250 WORDS)
Spectroelectrochemical Investigations of Soluble Polyaniline Synthesized via New Inverse Emulsion Pathway (2005)

A new inverse emulsion protocol has been developed for the synthesis of polyaniline (PANI), which can be dissolved completely in common organic solvents such as chloroform. Benzoyl peroxide is used as the oxidizing agent and toluene + 2-propanol−water is used as the solvent. Dodecylbenzenesulfonic acid (DBSA) has been selected as the dopant because it also functions as the surfactant. Cyclic voltammetry and spectroelectrochemical investigations were carried out to study the electroactivity, UV−Vis response, and metal-to-insulator transition of the chemically synthesized PANI as a function of applied electrode potential. At more positive potentials, cyclic voltammograms of PANI in aqueous acids show two oxidation waves caused by redox processes of PANI as observed with electrochemically prepared PANI. Peak position and shape are influenced by the slow anion exchange rate. Electrical conductivity of the material is relatively high as the minimum resistance value is nearly 10 Ω. SEM investigations show that the amount of DBSA in the feed strongly influences the morphology of the polymer. In situ UV−Vis spectroscopy measurements reveal good electrochromic reversibility for the polymer very similar to the response of PANI synthesized electrochemically.
Succeeding with technology : computer system concepts for real life (2009)

Succeeding with Technology - Third Edition presents the latest ways to get ahead and lead a successful, fulfilling life with technology. Building off the innovative approach from previous editions, it focuses on the newest trends that are impacting the way we live, while providing just the right amount of foundational concepts to provide a thorough understanding. By focusing on the application of technology and how technology may be used by students for personal and professional gain, this text gives students the information they need to prosper.
Innocency's Complaint (1920)

Bulletin of Friends' Historical Society of Philadelphia - Volume 10, Number 1, Eleventh Month (November) 1920
Adaptive Fast Quadtree Level Decision Algorithm for H.264 to HEVC Video Transcoding (2015)

High Efficiency Video Coding (HEVC) was developed by the Joint Collaborative Team on Video Coding to replace the current H.264/Advanced Video Coding (AVC) standard, which has dominated digital video services in all segments of the domestic and professional markets for over ten years. Therefore, there is a lot of legacy content encoded with H.264/AVC, and an efficient video transcoding from H.264/AVC to HEVC will be needed to enable gradual migration to HEVC. In terms of rate-distortion (RD) performance, HEVC roughly doubles the RD compression performance of H.264/AVC at the expense of a high computational cost. HEVC adopts a quadtree-based coding unit (CU) block partitioning structure that is flexible in adapting various texture characteristics of images. However, this causes a dramatic increase in computational complexity due to the necessity of finding the best CU partitions. This paper presents an adaptive fast quadtree level decision algorithm that is designed to exploit the information gathered at the H.264/AVC decoder in order to make faster decisions on CU splitting in HEVC using a Naïve-Bayes probabilistic classifier that is determined by a supervised data mining process. The experimental results show that the proposed algorithm can achieve a good tradeoff between coding efficiency and complexity compared with the anchor transcoder; moreover, it outperforms other related works available in the literature.