gebhart/patrepeval huggingface dataset:
A Servo-Control System Using a Self-Controlled Synchronous Motor (SCSM) with Sliding Mode Controller (1987)

The application of sliding mode control for improving the dynamic response of a self-controlled synchronous motor (SCSM) based position servo system is presented. Sliding mode control gives fast dynamic response with no overshoot and zero steady-state error. It has the important feature of being highly robust, i.e., insensitive to plant parameter variations and external disturbances. A design procedure is outlined for the sliding mode controller for a servo driving using the self-controlled synchronous motor. A novel scheme for fast torque reversal is proposed and implemented. Digital computer simulation of the overall position control system is carried out using a time domain model in the d-q reference frame. The rigorous simulation of the servo system with sliding mode control shows the existence of limit cycles in the position response with certain type of speed encoder. Experimental results are provided for a 3-hp synchronous motor based servo drive. The sliding mode controller is implemented using a single-board microcomputer which controls a GTO thyristor current source inverter to drive the motor.
ALS& Aging: A Case Study in Autonomy and control (1983)

Abstract Quality of life is often seen as an ideal that is impossible to achieve in long‐term care. This paper suggests that the maintenance of automony and control is basic to attaining the highest potential quality of life. Quality of care has become a particular concern in nursing. In the long‐term care setting, the quality of care has come to the attention of the public, resulting in a loud outcry against the nursing home industry as a whole. Even those facilities that already provide high‐quality nursing care must strive for even higher standards if they are to move health care delivery towards the ever elusive ideal–the greatest possible quality of life. Individualization of patient care has become a watchword in nursing. Yet it may be undermined by the health care system and by nursing staffing patterns in general and nursing philosophy and allocation of time in particular. Upon entering a long‐term care facility the geriatric patient loses much autonomy. Activities of daily living become regulated by the system and are determined by the time available for staff members to assist the patient. As the elderly become more physically disabled they become increasingly dependent on the staff, losing more and more control over their life‐style– when they rise, what they wear, even how they dress. Quality of life must be considered from a person's point of view and in relation to the capabilities of that person (Cassel, 1980). The maintenance of autonomy and control can be crucial in maintaining self‐esteem and achieving quality of life. Loss of control over the outcome of one's own behavior leads to helplessness. Helplessness is based on the perceptions and beliefs of the individual, whether they be founded on fact or fallacy (Seligman, 1975). The helpless individual too frequently lacks quality of life. This paper presents a plan for individualized care, which focuses on the issue of patient autonomy versus “adequate” nursing care. It was developed collaboratively between a patient and the authors–nurses who assume the role of consultant and patient advocate.
Impact of ligands on CO2 adsorption in metal-organic frameworks: First principles study of the interaction of CO2 with functionalized benzenes. I. Inductive effects on the aromatic ring (2009)

Intermolecular interactions between the CO2 molecule and a range of functionalized aromatic molecules have been investigated using density functional theory. The work is directed toward the design of linker molecules which could form part of new metal-organic framework materials with enhanced affinity for CO2 adsorption at low pressure. Two classes of substituted benzene molecules were considered: (i) with halogen substituents (tetrafluoro-, chloro-, bromo-, and dibromobenzene) and (ii) with methyl substituents (mono-, di-, and tetramethylbenzene). In the benzene-CO2 complex, the main interaction is between the delocalized π aromatic system and the molecular quadrupole of CO2. Halogen substituents have an electron-withdrawing effect on the ring which destabilizes the π-quadrupole interaction. Weak “halogen-bond” and hydrogen bondlike interactions partially compensate for this, but not to the extent that any significant enhancement of the intermolecular binding energy is observed. Methyl groups, on the other hand, have a positive inductive effect which strengthens the CO2-aromatic interaction by up to 3 kJ mol−1 in the case of tetramethylbenzene. Weak hydrogen bondlike interactions with methyl H also contribute to the stability of the complexes.
Textbook of Prostate Cancer: Pathology, Diagnosis and Treatment (1999)

1. Natural History 2. Pathology 3. Prostatic Intraepithelial Neoplasia 4. Cell Biology and Growth Factors 5. Immunology 6. Gene Therapy 7. Screening 8. Prostatic-Specific Antigen 9. Transrectal Ultrasound in Biopsy 10. Evaluation of Metastases: Nuclear Medicine/CT and MRI 11. Surgery 12. Radiotherapy 13. Down-Staging 14. Cryosurgery 15. Hormonal Manipulation: 16. Antiandrogens/Testicular 17. Androgen Ablation/Combined 18. Androgen Blockade 19. Relapse: Chemotherapy /Palliative 20. The Future
Progress in High Temperature Physics and Chemistry Vol3 (1970)

This volume consists of four individual contributions, there being no common theme. Taking the contributions in turn: 'Review of shock tube chemistry' by R A Strehlow is comprehensive over the period 1964–66 with some references in 1967 and 1968, and dovetails into a previous, comprehensive review referred to in the text.
Cost‐effectiveness of Prostate Health Index for prostate cancer detection (2011)

• The strategy PSA plus phi may be an important strategy for prostate cancer detection at both thresholds of PSA ≥2 ng/mL and PSA ≥4 ng/mL to recommend a prostate biopsy compared with using PSA alone.
MAPK signaling pathways in the regulation of hematopoiesis (2009)

Abstract Relevance of mitogen-activated protein kinases ERK, JNK, and p38 in the regulation of myeloid differentiation. The MAPKs are a family of serine/threonine kinases that play an essential role in connecting cell-surface receptors to changes in transcriptional programs. MAPKs are part of a three-component kinase module consisting of a MAPK, an upstream MEK, and a MEKK that couples the signals from cell-surface receptors to trigger downstream pathways. Three major groups of MAPKs have been characterized in mammals, including ERKs, JNKs, and p38MAPKs. Over the last decade, extensive work has established that these proteins play critical roles in the regulation of a wide variety of cellular processes including cell growth, migration, proliferation, differentiation, and survival. It has been demonstrated that ERK, JNK, and p38MAPK activity can be regulated in response to a plethora of hematopoietic cytokines and growth factors that play critical roles in hematopoiesis. In this review, we summarize the current understanding of MAPK function in the regulation of hematopoiesis in general and myelopoiesis in particular. In addition, the consequences of aberrant MAPK activation in the pathogenesis of various myeloid malignancies will be discussed.
THE DYNAMICS OF THE SENSITIZATION STRUCTURE IN CHILDREN WITH BRONCHIAL ASTHMA, LIVING IN LVIV (2019)

The second most common reason of sensitization were was epidermal allergens (52.1 % -471 children). Less commonly diagnosed was fungal (34.18% -309 patients), pollen (26.77 % -242 patients) and food (19.91 % -180 patients) sensitization.
Safety of Lane Change Maneuver Through A Priori Prediction of Trajectory Using Neural Networks (2012)

Lane change (LC) is a maneuver that allows drivers to enter into a lane that suits their requirements and comfort. The LC process requires the driver to assess its neighborhood traffic in its original and target lanes before undertaking the maneuver. Other vehicles in the neighborhood also need to adjust for safe lane change. The LC trajectory is determined by the accuracy of these subjective assessments as well as the state of traffic. An erroneous assessment by LC vehicle or neighboring vehicles or an incorrect maneuver can cause collision. The collision can be prevented if the LC trajectory can be predicted and the feasibility of LC can be communicated to different vehicles involved in this process. . In the present paper, neural network is used for long term forecast of the lane change trajectory and for short term near future positions of the LC vehicle. The neural network is trained using past LC trajectories of different vehicles. The trained network is then used for long and short term forecast of the vehicle’s positions during LC. Simulation results with actual filed data observed data indicates that neural network is able to learn LC maneuvers and is able to perform short term prediction with sufficient accuracy.
Completed suicide, depression, and RELN polymorphisms (2016)

The present investigation, performed on a study sample from a population with one of the highest suicide rates in the world, indicated an association between rs2965087 in the reelin gene and the expression of suicidal threats a month before suicide in contrast to other symptoms of depression.
Selegiline in adults with attention deficit hyperactivity disorder: clinical efficacy and safety. (1996)

Clinical effects of high-dose and low-dose selegiline treatment were examined in 24 adults with attention deficit hyperactivity disorder (ADHD). The study used a double-blind randomized three-arm parallel-groups design with a 2-week placebo baseline followed by 6 weeks of treatment (placebo, 20 mg/day, or 60 mg/day selegiline) and then by 2 weeks of placebo post-treatment. A two-way repeated measures analysis of variance (ANOVA) showed no Drug x Time interaction and no main effect of Drug on severity of ADHD symptoms as self-rated by the subjects on the Conners Abbreviated Teacher Rating Scale (Conners ATRS). There was a significant effect of Time, indicating decreased ADHD symptom severity scores in all three groups. Selegiline treatment was not more effective than placebo. Side effects were more severe in the high-dose selegiline group than in either of the other groups. These preliminary results must be interpreted with caution because of methodological limitations in terms of sample size, patient population selection, and measurement tools.
Molecular parameters and olfaction in the oriental fruit fly <i>Dacus dorsalis</i> (1981)

The methyl eugenol receptor of the male oriental fruit fly (Dacus dorsalis) has been further characterized by evaluating the role of the linear free energy parameters product operator and sigma in the depolarization of the receptor by 37 substituted 3,4-dimethoxybenzenes. There was a strong positive correlation between the hydrophobic character of the primary substituent and intense odor and a positive correlation between the electron donating property of the primary substituent and intense odor. Maximum odor intensity was also associated with substituents of 3 atomic diameters and was improved by a center of unsaturation. Preference tests suggest that this simple and versatile odor receptor can serve as a model for investigation of molecular interactions between receptors and odorant molecules.
Zeroing in on <i>ROS1</i> Rearrangements in Non–Small Cell Lung Cancer (2012)

Rimkunas and colleagues report on the development and validation of an immunohistochemical assay evaluating non-small cell lung cancers (NSCLC) for the presence of ROS1 fusions. The diagnostic was validated in a screen of 556 NSCLCs, identifying 9 (1.6%) tumors with oncogenic ROS1 rearrangements. These patients are candidates for ROS1-targeted therapies.
5‐Desaza‐ und 5‐Thiariboflavine: Ein einfacher Weg zu Antimetaboliten des Vitamins B<sub>2</sub> (1976)

Die Aufklärung biochemischer Reaktionswege wird durch Antimetabolite erleichtert. Der Vitamin‐B 2 ‐Antimetabolit ( 1 ) sowie die Analoga mit Soder SO statt C 5 H sind jetzt gut zugänglich geworden. magnified image
[Granulometric determination of the effect of polyvinylpyrrolidone on the dissolution rates of difficultyly soluble drugs (author's transl)]. (1980)

The authors investigated the usability of the TUR ZG 2 gramulometer for determining the dissolution rates of difficultly soluble drugs (prednisolone, nitrofurantoin, nitrofural), especially under the influence of polyvinylpyrrolidone (PVP K 25 and PVP K 90), and for characterizing the changes in dispersity of PVP suspension gels. The dissolution gels of all three drugs were considerably increased by PVP (1--10%). Principally, PVP suspension gels of these drugs underwent changes in dispersity during storage (20 weeks), the particle numbers of prednisolone preparations being doubled. The particle numbers of the nitrofurantoin and nitrofural preparations decreased continuously, beginning with the second week of storage, which may be attributed to an improvement in solubility due to the use of the macromolecular adjuvant. PVP K 90 improved the solubilities of the drugs to a greater extent than PVP K 25.
The Backward Span of the Corsi Block-Tapping Task and Its Association With the WAIS-III Digit Span (2008)

The Corsi Block-Tapping Task measures visuospatial short-term and working memory, but a standardized backward condition is lacking. The authors present a standardized backward procedure that was examined in 246 healthy older adults (ages 50 to 92), comparing the results with the Digit Span subtest of the Wechsler Adult Intelligence Scale--Third Edition. Principal component analysis resulted in a two-factor model, dissociating a verbal and a spatial working-memory factor. Also the Corsi backward is not more difficult than the Corsi forward, in contrast to the Digit Span backward that is more difficult than the Digit Span forward. This may suggest that the Corsi Block-Tapping Task backward task relies on processing within working-memory's slave systems, whereas the Digit Span backward also relies on the central executive component of working memory. Finally, regression-based normative data and cutoff scores for older adults are presented for use in clinical practice.
Combined key-frame extraction and object-based video segmentation (2005)

Video segmentation has been an important and challenging issue for many video applications. Usually there are two different video segmentation approaches, i.e., shot-based segmentation that uses a set of key-frames to represent a video shot and object-based segmentation that partitions a video shot into objects and background. Representing a video shot at different semantic levels, two segmentation processes are usually implemented separately or independently for video analysis. In this paper, we propose a new approach to combine two video segmentation techniques together. Specifically, a combined key-frame extraction and object-based segmentation method is developed based state-of-the-art video segmentation algorithms and statistical clustering approaches. On the one hand, shot-based segmentation can dramatically facilitate and enhance object-based segmentation by using key-frame extraction to select a few key-frames for statistical model training. On the other hand, object-based segmentation can be used to improve shot-based segmentation results by using model-based key-frame refinement. The proposed approach is able to integrate advantages of these two segmentation methods and provide a new combined shot-based and object-based framework for a variety of advanced video analysis tasks. Experimental results validate effectiveness and flexibility of the proposed video segmentation algorithm.
Nonimmune IgM, but not IgG binds to the surface of Plasmodium falciparum-infected erythrocytes and correlates with rosetting and severe malaria. (2002)

Recent work suggests that IgG and IgM from nonimmune human serum (natural antibodies) bind to the surface of Plasmodium falciparum-infected erythrocytes and contribute to rosette formation by stabilizing the interaction between infected and uninfected erythrocytes. Here we show, in both laboratory clones and field isolates, that only IgM but not IgG is detected on the surface of infected cells. In field isolates, there was a strong positive correlation between IgM binding and rosette formation (Spearman's rank correlation coefficient p = 0.804, P < 0.001). Both rosette formation and IgM binding were associated with severe malaria, although statistical analysis indicates that rosette formation is the more strongly associated variable. Rosette formation, but not IgM binding, was also associated with malarial anemia. We conclude that IgM is the predominant class of natural antibodies binding to the surface of infected erythrocytes. However, we could not confirm previous suggestions that infected erythrocytes are coated with nonimmune IgG, which could lead to their interaction with host Fcgamma receptors.
Infant leukemia: An analysis of nine chinese patients (1990)

A study was made of the cellular and molecular characteristics of nine Chinese infants, consecutively presenting with acute leukemia. Five cases were acute lymphoblastic leukemia (ALL); four were acute nonlymphoblastic leukemia (ANLL). Hyperleukocytosis, hepatosplenomegaly, and poor response to conventional therapy were common features, and CNS involvement was detected at diagnosis in three cases. The blast cells from all five cases with ALL expressed early B-cell markers, i.e., HLA-DR+, CD19+, but CD10-. Terminal deoxynucleotidyl transferase (TdT) was present in blasts from four of the five cases and periodic acid-Schiff staining in blasts from two patients only. The leukemic cells of one patient also showed positive nonspecific esterase activity and expressed myeloid-associated antigens CD33 (My9), CD11 (OkM1), and CD14 (My4 and Mo2). Molecular analysis of leukemic cell DNA from this and two other patients showed rearrangement of the immunoglobulin (Ig) heavy-chain genes, but without any evidence of kappa light-chain gene rearrangement. T-cell receptor (TCR) genes remained in the germline configuration in these cases. Cytogenetic analysis showed translocation t(4;11) (q21;q23) in all four cases studied. In the group of ANLL, three cases belonged to the M4 and one to the M2 subtype. Chromosomal abnormality involving 11q23 was also detected in two patients: t(11;17)(q23;q11) and del(11)(q14q23) in each case respectively. Neither Ig nor TCR gene rearrangement was present in blast cells from patients with ANLL. The data indicate that chromosomal rearrangement of band 11q23 was quite common in Chinese infants with either form of leukemia, a finding that may have pathogenetic implications.
Towards high‐eficiency silicon solar cells by rapid thermal processing (1994)

Abstract Rapid thermal processing can offer many advantages, such as small overall thermal budget and low power and time consumption, in a strategy focused on cost‐effective techniques for the preparation of solar cells in a continuous way. We show here that this very short duration (a few tens of seconds) of isothermal heating performed in a lamp furnace can be used for many thermal steps of silicon solar cell processing. Rapid thermal processing was applied to form the p‐n junction from a phosphorus‐doped spin‐on silica film deposted on (100) silicon substrates at typical processing temperatures between 800 and 1100°C. the solar cells showed conversion efficiencies as good as those processed in a conventional way.
In Vitro Activities of Voriconazole, Itraconazole, and Amphotericin B against <i>Blastomyces dermatitidis</i> , <i>Coccidioides immitis</i> , and <i>Histoplasma capsulatum</i> (2000)

The in vitro activity of voriconazole was compared to those of itraconazole and amphotericin B against the mold forms of 304 isolates of three dimorphic fungi, Blastomyces dermatitidis, Coccidioides immitis, and Histoplasma capsulatum. MICs were determined by a broth microdilution adaptation of the National Committee for Clinical Laboratory Standards M27-A procedure. RPMI 1640 medium was used for tests with voriconazole and itraconazole, whereas Antibiotic Medium 3 with 2% glucose was used for amphotericin B. Minimum fungicidal concentrations (MFCs) were also determined. Amphotericin B was active against all three dimorphic fungi, with MICs at which 90% of the isolates tested are inhibited (MIC(90)s) of 0.5 to 1 microg/ml. Itraconazole had MIC(90)s of 0.06 microg/ml for H. capsulatum, 0.125 microg/ml for B. dermatitidis, and 1 microg/ml for C. immitis. The MIC(90)s of voriconazole were 0.25 microg/ml for all three fungi. Amphotericin B was fungicidal for B. dermatitidis and H. capsulatum with MFCs at which 90% of strains tested are killed (MFC(90)s) of 0.5 and 2 microg/ml, respectively. It was less active against C. immitis, with MFCs ranging from 0.5 to >16 microg/ml. Voriconazole and itraconazole were lethal for most isolates of B. dermatitidis, with MFC(50)s and MFC(90)s of 0.125 and 4 microg/ml, respectively. Both azoles were fungicidal for some isolates of H. capsulatum, with MFC(50)s of 2 and 8 microg/ml for itraconazole and voriconazole, respectively; neither had a lethal effect upon C. immitis. Our results suggest that voriconazole possesses promising activity against these important human pathogens.
Microsoft Office Outlook 2007 Plain & Simple (2007)

Get the fast facts that make learning Microsoft Office Outlook 2007 plain and simple! This no-nonsense guide uses easy numbered steps and concise, straightforward language that show the most expedient ways to learn a skill or solve a problem.
Intradetrusor onabotulinumtoxinA injection: how I do it. (2013)

Overactive bladder is a highly prevalent condition that may have significant impact on quality of life. This condition may be idiopathic or may have a neurogenic etiology. Antimuscarinics have long been the preferred agents for the treatment of this condition. OnabotulinumtoxinA, an injectible agent that prevents presynaptic release of acetylcholine at the neuromuscular junction, has emerged as an important option in the management of patients with urinary incontinence caused by refractory detrusor overactivity. This manuscript describes our technique for performing utilizing this therapy, describes key equipment needed and provides technical tips for avoiding common pitfalls.