gebhart/patrepeval huggingface dataset:
Education in behavioral medicine (1998)

SUMMARY Behavioral medicine has become increasingly relevant in contemporaneous medical education over the past two decades, but adoption of its principles and methods has been slow. Behavioral medicine stresses the effects of human behavior on health and illness, using a bipsychosocial approach. It focuses on the doctor-patient relationship and the development of communication skills which can result in greater patient satisfaction and increased compliance, producing effective treatment which is also cost-effective. There are several models available for medical schools to use in order to integrate behavioral medicine into undergraduate medical education. The authors conclude that undergraduate medical education must include a behavioral medicine component in order to improve the health of the public and to meet the demands of a changing health-care system.
The aminopyrine breath test as a measure of liver function. A quantitative description of its metabolic basis in normal subjects. (1982)

The APBT is used widely as a measure of liver function. The development of the APBT into a liver function test of greater diagnostic value requires quantitative information on the processes involved in aminopyrine disposition and metabolism in man and on how APBT values reflect changes in these processes. A dual-isotope kinetic study of aminopyrine disposition and metabolism has been carried out on five normal adult subjects. Oral administration of 13C-aminopyrine (2 mg/kg) accompanied by simultaneous intravenous injection of 14C-aminopyrine was followed by serial measurements of aminopyrine and monomethylaminopyrine in plasma and urine over 6 hr. Timed collections of respiratory CO2 were analyzed for the content of excess 13CO2 and for 14CO2. On separate days, an intravenous bolus of 13C-labeled NaHCO3 was administered to obtain estimates of the kinetic parameters of CO2 elimination in each subject. These data were fitted simultaneously to a multicompartmental model that, in addition to providing hitherto unavailable quantitative information, has revealed that (1) demethylation is the major elimination pathway for aminopyrine; (2) a major alternative pathway not involving demethylation exists for monomethylaminopyrine; and (3) only 50% of the labeled carbon generated by demethylation eventually is oxidized to HCO3-. The sensitivity of seven types of APBT scores to 50% reductions in the rates of aminopyrine absorption, metabolism of monomethylaminoantipyrine, intermediate carbon metabolism, and bicarbonate kinetics was evaluated with breath test curves simulated using the APBT model. Every APBT score currently in use was affected by variations in both gastrointestinal output of aminopyrine and bicarbonate kinetics. There is a need for further development of selective scoring methods in the aminopyrine breath test.
The Saccharomyces cerevisiae Prp5 Protein Has RNA-dependent ATPase Activity with Specificity for U2 Small Nuclear RNA (1996)

The Saccharomyces cerevisiae protein Prp5 is a member of the "DEAD box" family of putative RNA-dependent ATPases and helicases. The protein was purified from Escherichia coli and determined to be an RNA-dependent ATPase. The ATPase activity is 7-fold more specific for full-length U2 than for any of the other small nuclear RNAs or nonspecific RNAs tested. An RNaseH assay in extracts was used to demonstrate that Prp5 mediates an ATP-dependent conformational change in the intact U2 small nuclear ribonucleoprotein. We propose that this conformational change makes the branch point pairing sequence of U2 RNA accessible for pairing with the intron allowing formation of the pre-spliceosome.
A New BODIPY Derivative Bearing Piperazine Group (2007)

A new BODIPY derivative bearing piperazine group was synthesized and its fluorescent changes towards metal ions as well as pH are studied. The title compound displayed a moderate selectivity for Hg2+ among the metal ions examined.
Microbiologic and clinical value of primary broth cultures of wound specimens collected with swabs (1997)

In order to assess the microbiologic and clinical value of primary broth culture of wound specimens collected with swabs and submitted to the laboratory in transport medium, we compared the results of primary agar culture with the results of a corresponding primary broth culture for 344 aerobic specimens and 176 anaerobic specimens. While 8.7% (45 of 520) of the specimens yielded organisms from the primary broth culture that were not recovered from the corresponding primary agar culture, only 5.0% (26 of 520) of the specimens yielded organisms from the primary broth culture other than Staphylococcus epidermidis, viridans group streptococci, and Corynebacterium spp. Moreover, the primary broth culture of only 0.6% (3 of 520) of the specimens yielded organisms not recovered from the primary agar culture that caused a change in the therapy of the patient. Our conclusion is that primary broth cultures are unnecessary for the processing of wound specimens properly collected with swabs.
State of Palaestra (2015)

The start of 2015 gives us time to reflect and look back on the state of Palaestra in 2014. First, we lost the great David Beaver, founder and longtime editor-in-chief of Palaestra . Founded in 1984, Palaestra recently reached its 30th year anniversary. David's vision was to create an applied journal that covered areas of sport, recreation, and physical education for individuals with disabilities. At the time, there was no such journal covering these topics. My legacy to David is to keep the journal running smoothly and at the high quality he established and maintained for over 30 years.
Long-term cancer survival prediction using multimodal deep learning (2021)

The age of precision medicine demands powerful computational techniques to handle high-dimensional patient data. We present MultiSurv, a multimodal deep learning method for long-term pan-cancer survival prediction. MultiSurv uses dedicated submodels to establish feature representations of clinical, imaging, and different high-dimensional omics data modalities. A data fusion layer aggregates the multimodal representations, and a prediction submodel generates conditional survival probabilities for follow-up time intervals spanning several decades. MultiSurv is the first non-linear and non-proportional survival prediction method that leverages multimodal data. In addition, MultiSurv can handle missing data, including single values and complete data modalities. MultiSurv was applied to data from 33 different cancer types and yields accurate pan-cancer patient survival curves. A quantitative comparison with previous methods showed that Multisurv achieves the best results according to different time-dependent metrics. We also generated visualizations of the learned multimodal representation of MultiSurv, which revealed insights on cancer characteristics and heterogeneity.
Digestibility of Fatty Acids in the Gastrointestinal Tract of Dairy Cows Fed with Tallow or Saturated Fats Rich in Stearic Acid or Palmitic Acid (1992)

Abstract Fatty acid digestibility was studied with five lactating cows fed three different fat sources in a 5 × 5 latin square experiment. The treatments were 500 g of tallow, 500 or 1000 g of saturated fat rich in stearic acid (C18:0) (SARF) or 500 or 1000 g of saturated fat rich in palmitic acid (C16:0) (PARF) per day. The total daily fatty acid intake was about 1100 g in rations with the highest fat inclusion. The fatty acid digestibilities were 76% for tallow, 74 and 64% for 500 and 1000 g SARF, respectively, and 87 and 81% for 500 and 1000 g of PARF, respectively. When compared to fatty acid digestibility for tallow predicted from a model based on literature values, PARF had a higher fatty acid digestibility at both fat intakes, and SARF had a lower fatty acid digestibility, especially at high fat intake.
Investigation of multiple orifice Air Jet Vortex Generators for flow control (2011)

An experimental investigation was conducted to determine the performance characteristics of an Air Jet Vortex Generator (AJVG) configured as a closely spaced arrangement of geometrically related orifices. Testing was conducted at a Reynolds number of 6.4 10 on a NACA 6 series airfoil equipped with an array of the devices. Early studies with multiple orifice AJVG's suggested that the incremental increases in performance did not justify the additional energy expended. However, more recent work indicates that a geometrically related series of orifices used with a related air injection velocity profile may yield results of greater promise. The AJVG was tested with two main groups of velocity profiles. Results obtained suggest that augmenting an AJVG with additional momentum provides additional incremental increases in lift coefficient, however; one group of velocity profiles appeared to provide total lift coefficient gains for less overall energy consumption compared with the other.
Estimation of Winter Snow Operation Performance Measures with Traffic Data (2012)

This research produced an automatic process to identify the road condition recovered times during snow events\nfrom the traffic-flow data. For this study, the traffic data from the past snow events were analyzed and the speed\nvariation patterns indicating the road condition recovery states during the recovery periods were identified. The\nprototype process developed in this study finds the speed change point indicating the recovery of the road condition\nby analyzing the speed variations for a given location. The process was then applied to a set of the past snow\nevents and the estimated recovered times were compared with the reported lane-regain time data.
<title>Polarization-based peak detection in laser triangulation-range sensors</title> (1996)

We report a polarization-based peak detection method for use in laser triangulation range sensors. Such sensors depend critically on the accurate detection of a pattern of laser light projected onto a scene, usually a point or line. Problems arise with highly specularly reflective surfaces, which can generate visible reflections of the light in various parts of the image. These can confuse intensity-based detection algorithms and lead to incorrect range measurements. This paper demonstrates the failure of intensity-based methods by reference to an existing triangulation scanner and sample depth data. A polarization-based method is proposed and we demonstrate experimentally the feasibility of polarization-based vision for disambiguating multiple specular inter-reflections of the laser light.
Distributed-current-feed and distributed-energy-store railguns (1984)

Distributed-type railguns are combinations of power supplies and railguns designed to maintain a nearly constant current in the armature of a railgun and to overcome the accelerator length limitations of simple breech-fed railguns. This limitation arises from the increasing resistance and inductance of the rails with increasing railgun length. The energy efficiency of a railgun system from the primary energy store to the kinetic energy of the projectile can be improved as compared to the simple railgun in some applications. This is accomplished by a reduction of the stored magnetic field energy in the bore of the railgun at the end of a shot and reduction of the resistive losses in the rails. The improved system performance of the distributed railguns over the simple breech-fed railguns is achieved at the expense of greater system complexity. The only distributed-type railguns that have been built to date are distributed-energy-store (DES) railguns. These systems presently use capacitors as the primary energy store, which allows the use of closing switches to initiate current from each of the stores. In this paper a new type of railgun, the distributed-current-feed (DCF) railgun, is presented. The DCF railgun system is a compromise in system complexity and efficiency between the DES railguns and the simple breech-fed railguns. Also, the DCF railgun utilizes closing switches in such a manner as to allow the use of a variety of primary power supplies, including homopolar generators (HPGs), for such electromagnetic propulsion tasks as space launches.
Circulating adiponectin levels during human endotoxaemia (2003)

Adiponectin, an adipocytokine secreted by fat tissue, may prevent development of diabetes type II, as high adiponectin levels are linked with insulin sensitivity. In contrast, tumour necrosis factor (TNF)-alpha, which is also produced by fat tissue, leads to insulin resistance and furthermore inhibits adiponectin mRNA production and secretion of the protein. However, adiponectin also negatively regulates TNF-alpha levels. Therefore, we set out to test whether an infusion of endotoxin would influence circulating adiponectin levels in healthy human subjects. Twenty-three healthy human subjects were injected with endotoxin (2 ng/kg body weight); eight of these subjects were also injected with saline and served as controls. Plasma levels of adiponectin, TNF-alpha and interleukin-6 were measured at 0, 1.5, 2, 4, 8 and 24 h. TNF-alpha and interleukin-6 levels peaked at 1.5 h and 2 h, respectively. Control subjects injected with saline showed a decrease in adiponectin plasma levels with time (P < 0.05) presumably owing to the effect of fasting or physical inactivity. However, there was no change in adiponectin plasma levels in endotoxin injected subjects, thus the effect of fasting was opposed. In conclusion, circulating adiponectin levels are reduced during a resting and fasting state, an effect reversed by endotoxin injection.
Debug of the CELL Processor: Moving the Lab into Silicon (2006)

With 234 million transistors, making up 9 processing units and 3 asynchronous clock domains in a high speed design, the CELL processor clearly presents a challenge to debug work required during lab bring-up and test bring-up. Traditional multi-processing systems reap the benefit of standard system level debug practices, but as the system has moved into the silicon so must the access during bring-up. This paper explains some of the innovative debug features included in the CELL processor design that were critical for efficient bring-up in a limited access environment
Searching the Most Appropriate Sample Pretreatment for the Elemental Analysis of Wines by Inductively Coupled Plasma-Based Techniques (2008)

Different sample preparation methods were evaluated for the simultaneous multielement analysis of wine samples by inductively coupled plasma optical emission spectrometry (ICP-OES) and inductively coupled plasma mass spectrometry (ICP-MS). Microwave-assisted digestion in closed vessel, thermal digestion in open reactor, and direct sample dilution were considered for the determination of Li, Be, Na, Mg, Al, K, Ca, Sc, Ti, V, Cr, Mn, Fe, Co, Ni, Cu, Zn, As, Se, Sr, Y, Mo, Cd, Ba, La, Ce, Pr, Nd, Sm, Eu, Gd, Tb, Dy, Ho, Er, Tm, Yb, Lu, Tl, Pb, and Bi in 12 samples of red wine from Valencia and Utiel-Requena protected designation of origin. ICP-MS allows the determination of 17 elements in most of the samples, and using ICP-OES, a maximum of 15 elements were determined. On comparing the sample pretreatment methodology, it can be concluded that the three assayed procedures provide comparable results for the concentration of Li, Na, Mg, Al, K, Ca, Mn, Fe, Zn, and Sr by ICP-OES. Furthermore, ICP-MS data found for Cu, Pb, and Ba were comparable. Digestion treatment provides comparable values using both total decomposition in open system and microwave-assisted treatment for Cu by ICP-OES and for Cr, Ni, and Zn by ICP-MS. Open vessel total digestion provides excess values for Cr, Mn, Fe, and Zn by ICP-OES and defect values for Se. However, direct measurement of diluted wine samples provided uncomparable results with the digestion treatment for Mn, Cu, Pb, Zn, Ba, and Bi by ICP-OES and for Mg, Cr, Fe, Ni, and Zn by ICP-MS. Therefore, it can be concluded that microwave-assisted digestion is the pretreatment procedure of choice for elemental analysis of wine by ICP-based techniques.
Acquisition of β-glucuronidase activity by deficient fibroblasts during direct contact with lymphoid cells (1982)

ABSTRACT Fibroblasts deficient in β-glucuronidase acquired high levels of this enzyme when they were co-cultured with concanavalin A-stimulated lymphocytes. Acquired enzyme activity, determined using a single-cell cytochemical assay, was directly proportional to the number of lymphocytes added and persisted for several days in fibroblasts maintained at high density. Lymphocytes did not secrete significant levels of β-glucuronidase into their culture medium, and did not release other substances able to induce synthesis of the enzyme by the deficient fibroblasts. Nor did β-glucuronidase acquisition result from concanavalin A-mediated uptake of enzyme, since a-methylmannoside did not reduce acquired activity. Moreover, lymphocytes from various sources, whether unstimulated or activated by a different mitogen, bacterial lipopolysaccharide, were equally effective in promoting the appearance of β-glucuronidase. Deficient fibroblasts did not acquire β-glucuronidase by active endocytosis when co-cultured with lymphocytes, since enzyme extracted from lymphocytes was not itself effective in this respect. Furthermore, mannose 6-phosphate, which did inhibit endocytosis by deficient fibroblasts of exogenous β-glucuronidase prepared from 3T3 cells, had no effect on enzyme acquisition by fibroblasts during their co-culture with lymphocytes. Conversely, inhibitors of protein synthesis and energy metabolism, which did not interfere with endocytosis of exogenous enzyme, abolished the acquisition of βglucuronidase during co-culture. Deficient fibroblasts did not acquire β-glucuronidase when they were cultured together with lymphocytes but separated from them by Millipore membranes permeable to exogenous enzyme. Thus, although the mechanism of acquisition is still unclear, the present results suggest that β-glucuronidase is transferred from lymphocytes to deficient fibroblasts by a process in which direct cell-to-cell contact is obligatory.
Notes on some Rock'Paintings at Savuti (1969)

Although the area is fairly well known (it forms a part of the Chobe National Park) Liversedge's report is the first record of these paintings. The nearest known paintings are those at Tsodilo an hundred and fifty miles to the west. The presence of the Tsodilo paintings, previously isolated from the great concentrations of paintings in Rhodesia over four hundred miles away, has always led experts to suspect that paintings would finally be discovered on the few hills between Rhodesia and Tsodilo. But most people had tended to examine Gcoha Hill, fifteen miles to the north-east of Savuti. The nearest site where they occur to the east of Savuti is at Kalomo in Zambia, where there is one site with a few faded red schematic paintings, themselves isolated from other Zambian or Rhodesian rock paintings by nearly two hundred miles.
A Comparison of Imaging Techniques for the Investigation of Normal and Disordered Speech Production (2001)

Recent years have seen the development of a set of speech imaging techniques that speech scientists have been able to use for the investigation of both normal and disordered speech production. The use of x-radiography techniques in speech science has become much less common due to the potential risks, so it is timely to review what alternatives are available. In this article, we describe three such approaches: magnetic resonance imaging (MRI), electromagnetic articulography (EMA), and ultrasound. The operating principles behind each technique are described, together with a review of relevant literature. Finally, we contrast the strengths and weaknesses of each imaging system in relation to their potential to be used in research and clinical applications with disordered speech.
Foods and diseases. (1977)

An examination was made of the statistical correlations between the main foodstuff and nutrient intakes and the chief causes of mortality in 20 different countries, comprising 17 in Europe, and Canada, USA, and Japan. Subsidiary examinations were made of the effects of including and excluding Japan, and of the effects of various statistical standardisation procedures. Complex food patterns were identified and related both to geographical latitude and to levels of affluence; these, in turn, were related to complex patterns of mortality. Criteria for drawing special attention to specific associations were identified, based partly on statistical significance tests and also on strength-of-association yardsticks supplied by diseases with known causes. Findings suggesting causal interpretations were: (a) alcohol intakes and cirrhosis of the liver, cancer of the mouth, and cancer of the larynx; (b) total fat intakes and multiple sclerosis, cancer of the large intestine, and cancer of the breast; and (c) beer and cancer of the rectum.
Gait in hemiplegia: evaluation of clinical features with the wisconsin gait scale (2007)

The Wisconsin Gait Scale is a useful tool to rate qualitative gait alterations of post-stroke hemiplegic subjects and to assess changes over time during rehabilitation training. It may be used when a targeted and standardized characterization of hemiplegic gait is needed for tailoring rehabilitation and monitoring results.
The relationship between interior office space and employee health and well-being – a literature review (2020)

<p>Health is a trending topic in the office market, yet scientific research on healthy offices is scattered. This study undertakes a systematic literature review on the relationship between the interior space of offices and physical, psychological and social well-being. The review identifies the characteristics of interior office space that have been studied in relation to employee health, and outlines the empirical evidence. Of 2816 papers in the database, 50 addressed the relationship between interior office space and health and did so based on six features: layout, furniture, light, greenery, controls and noise. Evidence on the relationship between interior space and health has accumulated only within a few topics. On the one hand, open-plan offices, shared rooms and higher background noise are negatively related to health. On the other hand, positive relationships are found between physical well-being and aspects that encourage physical activity; between physical/psychological well-being and (day)light, individual control and real/artificial greenery; and between social well-being and small shared rooms. In measuring health, physical well-being is predominant. Similarly, studies have predominantly aimed to prevent health problems rather than enhance health. Overall, the related research is in a nascent stage. Further research is required to verify claims about healthy offices.</p>
Cellular and humoral bases of hemorrhage-induced [depression of lymphocyte function (1986)

Bacterial infection often occurs after trauma and hemorrhage and is believed to be a reflection of a compromised host defense system. In the present study, the effect of hemorrhage on phytohemagglutinin-induced lymphocyte proliferation was investigated. Lymphocytes obtained from rats 2 h after blood withdrawal in an amount equivalent to 30% of total blood volume showed a 48% reduction in proliferative response as compared to cells obtained from the same animal before bleeding. This depression in lymphocyte proliferative capacity appeared to be due to a serum factor or factors induced by hemorrhage. The hemorrhage-induced serum factor(s) is heat-stable, dialyzable, and has an apparent molecular weight between 13,000 and 23,000 on gel filtration chromatography. The hemorrhage-induced factor seems to suppress lymphocyte proliferation in a rapid and irreversible manner. This abnormality in host defense mechanisms may contribute to the increased incidence of sepsis present after trauma and hemorrhage.