gebhart/patrepeval huggingface dataset:
Detection and identification of fungi in blood using broad‐range 28S rDNA PCR amplification and species‐specific hybridisation (2000)

The aim of the present study was to develop a PCR-based method to detect and identify fungi directly from human venous blood. We used broad-range PCR primers that targeted a part of the large subunit 28S rRNA genes. To obtain species-specific hybridisation probes, type strains of Candida albicans, C. glabrata, C. krusei, C. parapsilosis, C. tropicalis and Cryptococcus neoformans were PCR amplified, and the amplicons were analysed by gene sequencing. Based on the sequence analysis, species-specific probes that targeted variable regions were designed and used in hybridisation analyses. Between 2 to 10 fungal cells/ml of spiked blood samples could be detected and correctly identified to species. We applied the technique to blood samples obtained from two patients with or two patients without verified candidaemia. The three samples of candidaemia patients were correctly identified to species level, and those of the negative patients remained negative. This method is a potential tool for diagnosis of systemic invasive candidiasis.
Influence of Chemisorption on the Thermal Conductivity of Single-Wall Carbon Nanotubes (2004)

The thermal conductivity at 300 K of (10,10) carbon nanotubes that have been functionalized by chemical attachment of phenyl rings through covalent bonding (chemisorption) at random positions has been calculated as a function of adsorption density using classical trajectories. The system exhibits a rapid drop in thermal conductivity with chemisorption, where chemisorption to as little as 1.0% of the nanotube carbon atoms reduces the thermal conductivity by over a factor of 3. The simulation results indicate that the effect is due to a reduction in phonon scattering length rather than changes in the vibrational frequencies of the carbon atoms in the nanotube.
Using Linear Superposition to Solve Multiple Heat Source Transient Thermal Problems (2007)

For many years engineers have been using linear superposition to solve steady state thermal problems with multiple-heat-source systems. Predicting transient response of single-heat-source systems has been performed using R-C Foster networks with reasonable success. In most real applications there are multiple heat sources that are interacting perhaps in very complex ways in the time domain. Being able to simulate these interactions using a spreadsheet tool or a circuit simulator may be very advantageous to a device or application engineer designing or evaluating an application design. Using an RC-network model of a system to represent the individual transient response curves, we’ll show how to do this bookkeeping (and all the other calculations) for a simple system using Microsoft Excel. We’ll also see how to set up this sort of problem in a circuit simulator.
Horse race analysis in credit card fraud—deep learning, logistic regression, and Gradient Boosted Tree (2017)

Fraud detection is an industry where incremental gains in predictive accuracy can have large benefits for banks and customers. Banks adapt models to the novel ways in which “fraudsters” commit credit card fraud. They collect data and engineer new features in order to increase predictive power. This research compares the algorithmic impact on the predictive power across three supervised classification models: logistic regression, gradient boosted trees, and deep learning. This research also explores the benefits of creating features using domain expertise and feature engineering using an autoencoder-an unsupervised feature engineering method. These two methods of feature engineering combined with the direct mapping of the original variables create six different feature sets. Across these feature sets this research compares the aforementioned models. This research concludes that creating features using domain expertise offers a notable improvement in predictive power. Additionally, the autoencoder offers a way to reduce the dimensionality of the data and slightly boost predictive power.
Plasma Brain-Derived Neurotrophic Factor as a Peripheral Marker for the Action Mechanism of Antidepressants (2008)

Numerous studies have demonstrated that depression is associated with a decreased expression of brain-derived neurotrophic factor (BDNF). BDNF shows antidepressant-like effects in animal models. Therefore, we tested the hypothesis that BDNF might be a peripheral marker for the mechanism of action of antidepressant agents in humans. Thirty-two patients meeting the DSM-IV criteria for major depressive disorder and 50 normal control subjects were recruited for this study. Plasma BDNF levels and Hamilton Depression Rating Scales were measured at baseline and 6 weeks after antidepressant administration. At baseline, the mean plasma BDNF level was lower in the depressive patients (698.1 +/- 537.7 pg/ml) than in the control subjects (830.7 +/- 624.8 pg/ml), although the difference was not statistically significant (p = 0.33). The plasma BDNF levels in depressive patients significantly increased from 698.1 +/- 537.7 to 1,028.9 +/- 744.5 after 6 weeks of antidepressant treatment (p = 0.01). Moreover, plasma BDNF levels were significantly increased after 6 weeks of treatment in the responder group, while there was no statistically significant change in the unresponsive group. These results suggest that the therapeutic response after antidepressant administration might be attributable to the increase in BDNF levels. BDNF may play a critical role in the action mechanism of antidepressant drugs. Further studies with a larger number of subjects are needed to verify these findings.
Electrochemical Vapor Deposition of SOFC Components (1989)

The kinetics for film growth of yttria doped zirconia are modeled considering a Wagner oxidation process. The growth kinetics are examined as a function of reaction temperature, yttria content in the film, as well as the oxygen partial pressure gradient across the film. Calculated results indicate that only at temperatures above 1300 K, and low doping levels is the growth rate governed by the diffusion of electrons. With decreasing temperature and increasing yttria content the diffusion of holes becomes increasingly important in the growth rate. These model studies are used to explain differences in observed morphologies of EVD grown films of YSZ.
Effects of high-sulfur water and clinoptilolite on health and growth performance of steers fed forage-based diets1 (2010)

Sulfur-induced polioencephalomalacia (sPEM), a neurological disorder affecting ruminants, is associated with consumption of diets with increased S (high-S). High-S water is commonly found in many western states and is a major source of dietary S for grazing cattle. Consumption of high-S water has been associated with sPEM and decreased performance. Identification of a feed supplement that would counteract the negative effects of high-S water would decrease the incidence of sPEM and prevent performance reductions in regions with problematic water sources. The objectives of this study were to 1) determine the effects of administering high-S drinking water to forage-fed feedlot steers on health and performance, and 2) determine the effectiveness of clinoptilolite, a clay mineral with increased cation-exchange capacity, in negating the effects of high-S drinking water. Yearling steers (n = 96; 318.2 +/- 2.1 kg of BW) were randomly assigned to 1 of 4 treatments for a 77-d trial period: control with low-S water (566 mg of SO(4)/L), high-S water (3,651 mg of SO(4)/L), or high-S water plus clinoptilolite supplemented at 2.5 or 5.0% of the diet DM. Feed and water consumption were measured daily, and all steers were weighed on d -2, -1, 29, 53, 76, and 77. Plasma samples were collected on d 0, 58, and 77, and liver samples on d 0 and 77. There was a greater (P <or= 0.046) frequency of sPEM in high-S steers than control steers, but no differences among high-S treatment groups. In total, 12 cases of sPEM were confirmed by the presence of cortical lesions in steers consuming high-S water. Daily DMI (P = 0.002) and daily water intake (P = 0.001) were less in high-S water steers than control steers. No differences (P >or= 0.546) in ADG or G:F were observed. Plasma Cu decreased (P = 0.029) to a greater magnitude in high-S water steers than the control steers over the 77-d trial period. Mineral analyses of hepatic tissue from randomly selected healthy steers from each treatment group (n = 10 per treatment) showed an interaction (P <or= 0.034) of sample time and treatment for Cu, Se, and Zn concentrations. These results suggest that clinoptilolite does not negate the effects of high-S water, and administration of high-S water decreases herd health through an increased incidence of sPEM and reduced nutritional status.
Gaussian processes regressors for complex proper signals in digital communications (2014)

In this paper we develop the complex-valued version of the Gaussian processes for regression (GPR) for proper complex signals. This tool has proved to be useful in the nonlinear detection in digital communications in real valued models. GPRs can be cast as nonlinear MMSE where hyperparameters can be tuned optimizing a marginal likelihood (ML). This feature allows for a flexible kernel that can easily adapt either to a linear or nonlinear solution. We introduce the complex-valued form of the GPR, and develop it for the proper complex case. We also deal with the optimization of the ML. Some experiments included illustrate the good performance of the proposal.
Bedeutung der Gewichtung von Mengenangaben für die Unterscheidbarkeit von Waldgesellschaften (1993)

Bei Vegetationsaufnahmen wird häufig grosses Gewicht auf Mengenangaben gelegt. In der Praxis zeigt sich aber, dass diese Informationen oft irrelevant oder sogar irreführend sind. Detaillierte Mengenangaben sind nur bei bestimmten Fragestellungen und in bestimmten Pflanzenbeständen aussagekräftig.
Patented inhibitors of p53–Mdm2 interaction (2006 – 2008) (2010)

The discovery p53-Mdm2 protein-protein interaction inhibitors have delivered new potential options for a targeted cancer therapy with drug-like, non-toxic small molecules. If successful, this approach could gain considerably more attention in the pharmaceutical industry by targeting a variety of validated intracellular protein-protein interactions.
A critical review of Compton imaging. (1987)

This paper reviews the basic aspects, problems, and applications of Compton imaging including those related to nonmedical applications. The physics and technology at the base of this specific methodology are analyzed and the relative differences and merits with respect to other imaging techniques, using ionizing radiations, are reviewed. The basic Compton imaging approaches, i.e., point-by-point, line-by-line, and plane-by-plane, are analyzed. Specifically, physical design and technological aspects are reviewed and discussed. Furthermore, the most important clinical applications of the different methods are presented and discussed. Finally, possibilities and applications of the Compton imaging method to other nonmedical fields, as in the case of the important area of object defects recognition, are analyzed and reviewed.
Reducing the uncertainty in the data processing of PS converted waves (2009)

We developed a simplified approach to reduce the uncertainty in parameter estimation and data processing of PS converted waves. This is archived by using a simplified PS‐wave moveout. In this moveout. , a combination parameter, is used to replace the vertical Vp/Vs ratio, effective Vp/Vs ratio and PS‐wave anisotropy, and m, another combination of these parameters, is empirically set to a constant value. This allows to a moveout equation with two parameters without losing accuracy. can be converted into , and for prestack time migration. Tools are developed to estimate these parameters and apply the parameters to moveout correction and prestack time migration. Applying these tools to a real dataset shows that the new approach can reduce the uncertainty in parameter estimation and simplify the processing steps. The results obtained from the new approach are the same as that from the original method.
Excimer-Laser-Induced In-Situ Fluorine Passivation Effects on Polycrystalline Silicon Thin Film Transistors (1999)

We report a new fluorine passivation method without ion implantation and additional annealing step by low-temperature process and its effects on p-channel polycrystalline silicon (poly-Si) thin film transistors (TFTs). The proposed method is not post-passivation, but in-situ passivation because fluorine passivation is simultaneous with excimer-laser-induced crystallization by employing excimer laser annealing of fluorine-doped silicon oxide (SiO x F y ) on amorphous silicon (a-Si) structure. From experimental results, it has been shown that in-situ fluorine passivation is effective to improve the electrical characteristics, specially field-effect mobility, and the stability of p-channel poly-Si TFTs. The improvement is due to fluorine passivation, which reduces the trap state density and forms the strong Si-F bonds in place of the weak Si-H bonds in poly-Si channel and SiO 2 /poly-Si interface.
Hamiltonian Decomposition of the Rectangular Twisted Torus (2011)

We show that the 2a\times a rectangular twisted torus introduced by Cámara et al. [5] is edge decomposable into two Hamiltonian cycles. In the process, the 2a × a × a prismatic twisted torus is edge decomposable into three Hamiltonian cycles, and the 2a × a × a prismatic doubly twisted torus admits two edge-disjoint Hamiltonian cycles.
: An Historical Survey of Plymouth Colony (1999)

Abstract This introductory chapter explains the coverage of this book, which is about the family of the Pilgrims in Plymouth Colony. It explains the reasons for undertaking this study and discusses the voyages and experiences of Pilgrim settlers from Scrooby, England, before they reached the New World. The book examines the Pilgrims' housing, furnishings, family relationships, master-and-servant relations, and coming of age traditions.
The Nitrone Disodium 2,4-Sulphophenyl-<i>N</i>-Tert-Butylnitrone is Without Cytoprotective Effect on Sodium Nitroprusside-Induced Cell Death in N1E-115 Neuroblastoma Cells <i>in vitro</i> (2007)

Disodium 2,4-sulphophenyl-N-tert-butylnitrone (NXY-059) is a novel free radical-trapping compound that is neuroprotective in both rodent and primate models of acute ischaemic stroke. Neuroprotection in vitro by NXY-059 has not been reported previously, and we have now investigated whether such an effect can be detected using a simple cell culture model of neurotoxicity. Neuron-like cells of the neuroblastoma-derived clonal cell line N1E-115 were exposed to the free radical-generating agent sodium nitroprusside (SNP), which produced a concentration-dependent reduction in mitochondrial complex II activity 24 h later (EC(50) approximately 100 micromolar). Cell death induced by SNP (100 micromolar), assessed either by an increased proportion of apoptotic nuclear morphology or by mitochondrial complex II activity, was inhibited by a cocktail of known antioxidants (ascorbate, reduced glutathione, and dithiothreitol, all at 100 micromolar) but not by NXY-059 at a concentration known to be neuroprotective in vivo (300 micromolar). Disodium 2,4-sulphophenyl-N-tert-butylnitrone was also without effect on H(2)O(2)-mediated cytotoxicity. These results support recent data suggesting that in vivo NXY-059 probably acts at the neurovascular unit rather than at an intracellular site as a neuroprotective agent.
Synthesis of naphthalene containing aralkyl novolac epoxy resins for electronic application (2000)

Naphthalene containing aralkyl novolac epoxy resins were synthesized by the condensation of p-xylylene glycol with 2,7-dihydroxynaphthalene or 2-naphthol followed by the epoxidation of the resulting aralkyl novolacs with epichlorohydrin. The mechanical and dynamic viscoelastic properties of cured aralkyl novolac epoxy resins were investigated. Comparisons of mono- and di-functional naphthalene containing aralkyl novolac epoxy resins based on thermal and moisture absorption properties were also studied. The results indicate that a naphthalene containing aralkyl epoxy resin made from the difunctional naphthol has a low coefficient of thermal expansion, high heat resistance, and low moisture absorption.
Evaluation of a rapid specific ward based assay for creatinine in blood. (1995)

We have evaluated a dry reagent stick test for the quantitation of creatinine in plasma employing a whole blood sample. The assay was found to be specific for creatinine and correlated well (r = 0.993) with an established laboratory procedure. The precision found indicated that the method was suitable for use in the diagnosis and monitoring of renal disease.
Psychological Distress, Emotional Stability, and Emotion Regulation Moderate Dynamics of Herpes Simplex Virus Type 2 Recurrence (2014)

Results are consistent with research indicating that psychological distress suppresses immune system functioning, and provide new evidence that genital HSV-2 viral shedding is related to, and regulated by, psychological distress.
Acute pancreatitis: Etiology and common pathogenesis (2009)

Acute pancreatitis is an inflammatory disease of the pancreas. The etiology and pathogenesis of acute pancreatitis have been intensively investigated for centuries worldwide. Many causes of acute pancreatitis have been discovered, but the pathogenetic theories are controversial. The most common cause of acute pancreatitis is gallstone impacting the distal common bile-pancreatic duct. The majority of investigators accept that the main factors for acute billiary pancreatitis are pancreatic hyperstimulation and bile-pancreatic duct obstruction which increase pancreatic duct pressure and active trypsin reflux. Acute pancreatitis occurs when intracellular protective mechanisms to prevent trypsinogen activation or reduce trypsin activity are overwhelmed. However, little is known about the other acute pancreatitis. We hypothesize that acute biliary pancreatitis and other causes of acute pancreatitis possess a common pathogenesis. Pancreatic hyperstimulation and pancreatic duct obstruction increase pancreatic duct pressure, active trypsin reflux, and subsequent unregulated activation of trypsin within pancreatic acinar cells. Enzyme activation within the pancreas leads to auto-digestion of the gland and local inflammation. Once the hypothesis is confirmed, traditional therapeutic strategies against acute pancreatitis may be improved. Decompression of pancreatic duct pressure should be advocated in the treatment of acute pancreatitits which may greatly improve its outcome.
Sheared Edge Characterization of Steel Products used for Closure Panel Applications (2006)

<div class="htmlview paragraph">Application of Advanced High Strength Steels (AHSS) to closure and structural parts in the automotive industry is increasing in future models. In addition to weight reduction, the other primary motivation to consider these products is the improvement of structural performance that is needed to meet future stringent safety standards. AHSS products have a combination of unique microstructures and mechanical behavior. It is important to develop basic knowledge and understanding of all the manufacturing aspects of forming these products, so that robust forming processes can be engineered to successfully form parts in a production environment. The edge condition obtained after post-draw operations such as trimming has a significant influence on processes such as stretch flanging. A study to investigate the influence of punching clearance on the edge characteristics of various AHSS products has been initiated at Mittal Steel R&amp;D. Hole expansion test conducted using a conical punch was used as a measure of stretch flangeability of products with different edge conditions. Results for DP500 product and the commonly used BH210 and DQSK used for closure applications are presented in this paper. In addition, guidelines to obtain optimum edge conditions to facilitate successful stretch flanging will be discussed.</div>
Control and function of sebaceous glands (1989)

This review describes the various types of sebaceous glands, their locations, and where possible their different functions. All sebaceous glands are similar in structure and secrete sebum by a holocrine process. However, the nature of this secretion and the regulation of the secretory process seem to differ among the various types of glands. Methods for measuring sebum secretion and assessing sebaceous gland activity are also described. The area of major interest during the last 20 years has undoubtedly been the mechanisms that control sebaceous gland function. Most studies have focused on the endocrine control and in particular on the role of androgens and pituitary hormones, although evidence suggests that nonendocrine factors may also be important. However, many questions remain and during the next few years attention will certainly be given to the role of retinoids and their mode of action in the treatment of acne.
Intelligent multi-player smart grid management considering distributed energy resources and demand response (2010)

The smart grid concept is rapidly evolving in the direction of practical implementations able to bring smart grid advantages into practice. Evolution in legacy equipment and infrastructures is not sufficient to accomplish the smart grid goals as it does not consider the needs of the players operating in a complex environment which is dynamic and competitive in nature. Artificial intelligence based applications can provide solutions to these problems, supporting decentralized intelligence and decision-making. A case study illustrates the importance of Virtual Power Players (VPP) and multi-player negotiation in the context of smart grids. This case study is based on real data and aims at optimizing energy resource management, considering generation, storage and demand response.
Opportunistic File-Associations for Mobile Operating Systems (2006)

This paper presents the design and implementation of opportunistic file-associations, designed to decouple the storage and handling of user files in a mobile device. A file with an opportunistic file-association is not limited to a local application environment on a mobile device. Rather, the runtime environment supporting opportunistic file associations causes a user file to be opened at the most appropriate device in the environment of the user
Virus Disease of Small Fruits (1987)

This illustrated handbook was compiled by international authorities on virus and viruslike diseases of small fruits. Crops covered are in the plant genera Fragaria (strawberry), Vaccinium (blueberry and cranberry), Ribes (currant and gooseberry), and Rubus (blackberry and raspberry). The history, geographic distribution, importance, symptoms, transmission, cause, detection, and control of virus and viruslike diseases attacking these crops are discussed.
Improvement of detection specificity of <i>Plasmodium</i>‐infected murine erythrocytes by flow cytometry using autofluorescence and YOYO‐1 (2005)

The method described is robust, increases the specificity and sensitivity of detection in routine testing, and is especially well suited for detection of low parasitemias in murine models of malaria.