gebhart/patrepeval huggingface dataset:
Molecular Evidence on Changing Pattern of Mixed Plasmodium falciparum and P. vivax Infections during Year-Round Transmission of Malaria in Chahbahar, Iran (2004)

Mixed malaria infections, Plasmodium falciparum and P. vivax, are suspected to occur at a greater frequency than is detected by conventional light microscopy. In order to determine the year round pattern of transmission and the frequency of mixed infections in malaria endemic area, we carried out a prospective comparison of diagnosis by conventional light microscopy and nested PCR in Chahbahar district, south-eastern part of Iran. Out of 280 Giemsa-stained slides, 158 (56.42%) were identified as having only P. vivax and 89 (31.78%) were P. falciparum infection by microscopy. Only eight slides (2.8%) were interpreted as having mixed P. vivax-P. falciparum infections and 25 (8.9%) were negative. Comparing to the microscopy results, the PCR detected 33 more mixed infections. These results showed that the number, of mixed infections was increased during April to September and reduced after September, although malaria cases with only P. falciparum were increased. The possibility that malaria patients in Chahbahar district may have undetected mixed infections during first peak of transmission should be kept in mind because of the specific therapy required both for P. falciparum and for radical cure of P. vivax. Iran. Biomed. J. 8 (2): 89-93, 2004
Production Forecasting in Unconventional Resources using Data Mining and Time Series Analysis (2014)

Abstract Production forecasting in shale reservoirs is a challenging task because of the complex influences of geology, lithology, stimulation practices, etc. The large well count makes history matching and forward simulation particularly time consuming and laborious. In such a context, it is important to consider alternative methods, and to this end, we have developed two new methods of forecasting production. The first method uses data mining techniques, which allow the analysis of large quantities of data to discover meaningful pattern and relationships. These can subsequently be used for prediction. Some common data mining tools are neural networks (NN), genetic algorithms (GA), and self-organizing maps (SOM). Our method uses NN for predicting the future performance of a shale gas well based on historical production data of the previous year. The decline in production is captured during the NN training process and applied to the production data during the forecasting phase. The model is simple, elegant and fast and is able to forecast production in an unconventional play with reasonable tolerance. The second method uses time series analysis. It the trend, changes in value, rate of decline, and correlation with the past to generate a rapid and accurate forecast. The stock markets use this technique, and it is safe to say that if it can predict the stock ticks, then it can yield good results on a fluctuating, but surely declining, production rate. These methods are elegant and fast and are able to forecast production in an unconventional play with reasonable tolerance. They are not data intensive and can also be automated to be applied to a large number of wells, which makes them particularly useful in integrated operations in which a comparison of actual versus predicted behavior would enable operators to quickly identify problem wells for a more detailed investigation. The methods were applied to wells from the Barnett, Bakken, and Eagle Ford plays.
An analysis of the in-plane acceleration sensitivity of contoured quartz resonators with rectangular supports (2002)

It is shown that the resultant in-plane acceleration sensitivity of contoured quartz resonators symmetrically supported along rectangular edges always vanishes. This result is essentially a consequence of symmetry and applies to any shape for which the support system is symmetric with respect to the center of the mode shape. When the active plate is supported on one side only, a state of flexure is induced in the resonator which degrades the in-plane sensitivity. This emphasizes the importance of a symmetric support system to achieve low acceleration sensitivities. The extensional and induced in-plane flexural biasing deformations are determined by means of the variational approximation procedure using the variational principles in which all conditions appear as natural conditions. The resulting biasing states are used in a perturbation equation along with the mode shapes of the contoured resonators to calculate the non-vanishing acceleration sensitivities.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Measurement of High-Energy Direct Photons in<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mi>ψ</mml:mi></mml:math>Decays (1980)

The inclusive $\ensuremath{\gamma}$ and ${\ensuremath{\pi}}^{0}$ momentum distributions at the $\ensuremath{\psi}$ have been measured. Using these data and estimates of $\ensuremath{\eta}$ production, it is found that (4.1 \ifmmode\pm\else\textpm\fi{} 0.8)% of $\ensuremath{\psi}$ decays contain a direct photon with energy greater than 60% of the beam energy. The expected momentum distribution for direct photons calculated to lowest order in quantum chromodynamics is qualitatively different from that observed in the data.
Energy transfer and CW laser action in Er<inf>2</inf>O<inf>3</inf>:Ho<sup>3+1</sup> (1966)

Summary form only, as given. Er2O2Ho3+ is an unusual laser material in that the host crystal itself provides the dominant pumping mechanism by means of energy transfer. The phenomenon of energy transfer between rare earth ions wherein the fluorescent intensity of one ion is enhanced by energy transfer from another ion has been investigated for the case of transfer from Er3+ to Ho3+ by Johnson et aL2s3 Erz03 is a rugged, refractory material which crystallizes with the type-C cubic rare earth sesquioxide structure. Substitution of other trivalent rare earths is easily effected without charge compensation. Erz03 is thus an ideal host for utilizing high concentrations.
The CLIC Main Linac Module Updated Design (2017)

In 2016, CLIC implementation working groups have started their reflection on how to finalize the CLIC design work in the different areas of the project, aiming for a technical design and an overall implementation plan for CLIC being available for the next European Strategy Update around 2019. One of the working groups has focused its attention on the Main Linac hardware, which has brought together the different competences of the study with the aim of producing an advanced set of specifications for the design, installation and operation of the CLIC module. As the fundamental unit for the construction of the Main Beam linac, the CLIC module needs to move from the existing prototypes exploring its performance into an advanced and functional unit where the full life cycle of the module is considered. The progress of the working group activity is summarized in this paper, with considerations on the requirements for the design of the next-phase CLIC module.
Histological evaluation of dermal tissue remodeling with the 1444‐nm neodymium:yttrium–aluminum–garnet laser in <i>in vivo</i> model (2013)

Laser lipolysis has a skin tightening effect by heating the deep dermis, in addition to the removal of fat tissues. The 1444-nm neodymium:yttrium-aluminum-garnet (Nd:YAG) laser has been expected to be more effective and safe for laser lipolysis, due to higher affinity to fat and water, than 1064-nm and 1320-nm wavelengths. The purpose of this study was to evaluate the skin tightening effect of the 1444-nm Nd:YAG laser through in vivo guinea pig models. The 1444-nm Nd:YAG laser was used to irradiate shaved dorsal skin of the guinea pigs and compared with controls (no power, only tunneling). Immediately, 1 week, 1 month and 3 months after laser administration, full-thickness skins were harvested and to evaluate dermal thickness, collagen organization, fibroblast proliferation, and intensity of elastic fibers and mucopolysaccharides, using hematoxylin-eosin, Masson-trichrome, Verhoeff's stain and Alcian blue stain. Dermal thickness showed an increase with time in all groups. In collagen organization, fibroblast proliferation, and intensity of elastic fibers and mucopolysaccharides, the treatment groups were higher than those of the control group, overall. Our study showed that the 1444-nm Nd:YAG laser appeared to be effective for the skin tightening effect in in vivo guinea pig models. The 1444-nm Nd:YAG laser can be used for skin tightening, as well as reduction of fat tissues.
PROLONGATION OF RAT CARDIAC ALLOGRAFT SURYIYAL BY SPLEXECTOMY FOLLOWING TRANSPLANTATION (1974)

Section of Plastic and Reconstructive Surgery Veterans Administration Hospital Palo Alto, California 04304 and Divisions of Plastic and lieconstrurtirc Surgery and Cardiovascular Surgery Stanford University Medical School Stanford, California O43O5
THE SELECTIVE NEURONAL UPTAKE AND RELEASE OF [<sup>3</sup>H]DL‐2,4‐DIAMINOBUTYRIC ACID BY RAT CEREBRAL CORTEX (1978)

Abstract— At 25°C the accumulation of [ 3 H] dl ‐2,4‐diaminobutyric acid (DABA) into small rat cortical slices was linear with time and a tissue: medium ratio of 35:1 was attained after 60 min. At 37°C the uptake was no longer linear and the tissue: medium ratio at 60 min was 66:1. Uptake was unaffected by the addition of 10 μ m ‐AOAA and dependent on the presence of Na + in the incubation media. The uptake was shown to have a high affinity component with a K m of 20.7 μ m and a V max of 28.6 nmol/g/min. IC50's for the inhibition of [ 3 H]DABA uptake by dl ‐DABA, l ‐DABA and GABA were 80, 40 and 17 μ m respectively. Two m m β ‐alanine, however, caused less than 13% inhibition of [ 3 H]DABA uptake. Electron microscopic autoradiographs showed the [ 3 H]DABA to be accumulated by 22% of the identifiable nerve terminals and, after 14 days exposure, the density of silver grains over nerve terminals was 36–38 times higher than that over the rest of the electron micrograph. On the other hand, [ 3 H]DABA was not taken up into rat sensory ganglia and light level autoradiography showed the small amount of [ 3 H]DABA accumulated by the ganglia to be evenly distributed throughout the tissue. Both electrical stimulation for 30 s and exposure of the tissue to a medium containing 47 m m ‐K + for 2 min caused a marked increase in the efflux of [ 3 H]DABA from the tissue. Both these effects were abolished by a reduction in Ca 2+ concentration and an increase in the Mg 2+ concentration of the superfusing medium. These results suggest that l ‐DABA acts as a ‘false transmitter’ for the neuronal uptake, storage and release of GABA.
Cross-Reactivity of a Monoclonal Antibody to the Amino Terminal Region of Thyrotropin Receptor with the Serum Protein Alpha <sub>1</sub> -Antitrypsin (2002)

In a study designed to detect the presence of soluble, secreted A subunit of thyrotropin hormone receptor (TSHR) in serum, using anti-TSHR murine antibodies (mAbs) and peptide specific antiserum for Western blotting of human serum proteins fractionated by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) it was consistently observed that only one mAb, termed A10, reacted strongly with the 53 kd serum protein. The reaction was specific with the mAb A10 only, but not with another mAb or polyclonal antiserum. Furthermore, A10 immunoreactivity was documented in a variety of sera from healthy donors and patients, including patients whose thyroid gland was ablated during treatment for thyroid cancer. This suggests that the A10 cross-reactive protein was not derived from thyroid cells. The A10 cross-reactive protein was purified from normal serum and subjected to N-terminal sequence analysis, which identified the protein as alpha(1)-antitrypsin. Further experiments by enzyme-linked immunosorbent assay (ELISA) and the binding of antibody with deglycosylated or elastase-treated purified serum protein confirmed the cross-reactivity of mAb A10 with alpha(1)-antitrypsin. Alignment of the TSHR amino acid sequence with that of alpha(1)-antitrypsin identified five identical amino acids in a short stretch of residues 34-39 (EEDFRV) in TSHR and residues 205-210 (EEDFHV) in alpha(1)-antitrypsin. Analysis of the structural model of alpha(1)-antitrypsin revealed that these residues were exposed on the surface of alpha(1)-antitrypsin and were accessible for antibodies. Autoantibodies in patients with Graves' disease do not appear to recognize this region of the receptor and hence do not react with serum alpha(1)-antitrypsin.
Failure to detect platelet-activating factor using the splenectomized mouse bioassay (1991)

The ability of purified preparations of platelet-activating factor (PAF), from three different suppliers, to induce thrombocytopaenia in mice after splenectomy and to activate mouse platelets in vitro was examined. Although the PAF preparations were potent activators of horse and cow platelets in vitro, injections of up to 1 microgram PAF failed to elicit thrombocytopaenia responses in either CD1 or Swiss Webster random-bred mice. However, when thrombin was injected into Swiss Webster mice, a dose-dependent decrease in the concentration of platelets was observed. Furthermore, isolated platelets from these strains and from 3 inbred lines (C3H/He, BALB/c, C57BL/6) of mice, were not aggregated by PAF in vitro but were sensitive to adenosine diphosphate and thrombin. No change in circulating platelet concentrations was observed over the initial 7 days of gestation in intact Swiss Webster and C57BL/6 or splenectomized C57BL/6 mice, suggesting either an absence of PAF production during early pregnancy in these strains or insensitivity of their platelets to PAF. These results suggest that many mouse strains are unsuitable for the bioassay of PAF.
Suprachoroidal Septic Effusion Leading to Panophthalmitis Following Strabismus Surgery (2005)

We describe a case of endophthalmitis following strabismus surgery. Drainage of the suprachoroidal effusion with injection of antibiotics was unsuccessful in salvaging vision. Endophthalmitis following strabismus surgery may present with findings simulating a choroidal effusion or hemorrhage. Treating physicians should be alert to signs and symptoms of this severe complication of strabismus surgery in preverbal children.
Arquitectura de publicación automatizada de contenidos educativos supervisados en Internet (1999)

Trabajo presentado a las II Jornadas de Ingenieria Telematica JITEL'99, Madrid, 15-17 de septiembre de 1999
Herzenbergite and Sn-bearing tinzenite from the NYF pegmatite in Třebíč Pluton, Moldanubicum, Czech Republic (2006)

Herzenbergite and Sn-bearing tinzenite from the NYF pegmatite in Třebic Pluton, Moldanubicum, Czech Republic
SERENADE: safer and ecodesign research and education applied to nanomaterial development, the new generation of materials safer by design (2017)

The SERENADE project aims to develop and apply the “safer by design” process to create safer nanoproducts.
Effects of age and sex on the pharmacokinetics of LCZ696, an angiotensin receptor neprilysin inhibitor (2015)

LCZ696, a novel angiotensin receptor neprilysin inhibitor, is in development for the treatment of heart failure. Administration of LCZ696 results in systemic exposure to sacubitril (inactive prodrug of LBQ657), LBQ657 (neprilysin inhibitor), and valsartan (angiotensin II receptor blocker). We investigated the potential effects of age and sex on the pharmacokinetics of LCZ696 analytes (LBQ657 and valsartan) in an open-label, single oral dose (400 mg), parallel-group study in healthy subjects. Among 36 enrolled subjects, there were 19 male and 17 female subjects; 18 subjects were 18-45 years old (young), and 18 subjects were 65 years of age or older (elderly). Compared with young subjects, the AUCinf and T1/2 for LBQ657 were 42% and 30% greater, respectively, in elderly subjects. The Cmax for LBQ657 was similar between age groups. The AUCinf, Cmax, and T1/2 for valsartan were 30%, 24% greater, and 3.35 hours longer, respectively, in the elderly when compared with young subjects. All pharmacokinetic parameters of LCZ696 analytes (LBQ657 and valsartan) were similar between male and female subjects, indicating no effect on the pharmacokinetics of LCZ696 analytes based on sex. Considering the magnitude of change and its clinical significance, dose adjustment based on age or sex is not considered necessary.
Entanglement entropy of multipartite pure states (2003)

Consider a system consisting of n d-dimensional quantum particles and an arbitrary pure state $|\ensuremath{\Psi}〉$ of the whole system. Suppose we simultaneously perform complete von Neumann measurements on each particle. The Shannon entropy of the outcomes' joint probability distribution is a functional of the state $|\ensuremath{\Psi}〉$ and of n measurements chosen for each particle. Denote $S[\ensuremath{\Psi}]$ the minimum of this entropy over all choices of the measurements. We show that $S[\ensuremath{\Psi}]$ coincides with the entropy of entanglement for bipartite states. We compute $S[\ensuremath{\Psi}]$ for some special multipartite states: the hexacode state $|H〉$ $(n=6,$ $d=2)$ and the determinant states $|{\mathrm{Det}}_{n}〉$ $(d=n).$ The computation yields $S[H]=4\mathrm{log}2$ and $S[{\mathrm{Det}}_{n}]=\mathrm{log}(n!).$ Counterparts of the determinant state defined for $d<n$ are also considered.
Site‐directed mutagenesis and chemical modification of the two cysteine residues of the UDP‐<i>N</i>‐acetylmuramoyl:<scp>l</scp>‐alanine ligase of <i>Escherichia coli</i> (1998)

Site-directed mutagenesis and chemical modification of the two cysteine residues of the MurC L-alanine-adding enzyme from Escherichia coli were undertaken to study their possible role in activity and stability. Their replacement by alanine was not critical for activity. However, C230 played a role in enzyme stability and substrate binding. N-Ethylmaleimide alkylation led to monoalkylated and dialkylated proteins. The monoalkylated protein had mostly unmodified C230 residues. The extent of alkylation of C230 paralleled the loss of activity, whereas that of C426 did not. Protection against inactivation by beta,gamma-imidoadenosine 5'-triphosphate implied the involvement of C230 in the ATP binding site.
Verification of Stable Circuit Operation of 180nm Current Controlled MOS Current Mode Logic under Threshold Voltage Fluctuation (2010)

We have succeeded in fabricating 180nm Current Controlled MOS Current Mode Logic (CC-MCML) and verified the stable circuit operation of 180nm CC-MCML under threshold voltage fluctuations by measurement. The performance stability of the CC-MCML inverter under the fluctuations of threshold voltage of NMOS and PMOS is evaluated from the viewpoint of diminishing the bias offset voltage ΔVB. The ΔVB, that is defined as (base voltage of output waveform) - (base voltage of input waveform), is a key design parameter for differential circuit. It is shown that when the threshold voltage of NMOS fluctuates in the range of 0.53V to 0.69V, and threshold voltage of PMOS fluctuates in the range of -0.47V to -0.67V, the CC-MCML technique is able to suppress ΔVB within only 30mV, where as the conventional MCML technique caused maximum ΔVB of 1.0V. In this paper, it is verified for the first time that the fabricated CC-MCML is more tolerant against the fluctuations of threshold voltages than the conventional MCML.
P‐20: A Predictor Method Based on Neural Network for CRT Cut‐off Potential Control (2001)

Abstract A predictor system based on neural network to control the cut‐off potential voltage within a stable range in CRT manufacturing was proposed. The neural networks and the genetic algorithms are presented for minimize the error value between the predicted and the desired by regulating the affect parameters. Utilizing this forecast system, the mechanical factors could be adjusted in advance and the cut‐off potential voltage would have a suitable control. This method is applied on the quality assurance department to demonstrate the stability of the cut‐off potential voltage and the CRT mass production performance.
Blood Group‐Active Surface Molecules of the Human Red Blood Cell (1990)

The surface of the human red blood cell is dominated by a small number of abundant blood group active proteins. The major proteins are the anion transport protein (band 3) which has AB(H) activity, and Glycophorin A which has MN activity. Band 3 and Glycophorin A are of equal abundance in the normal red cell membrane (approximately 10(6) copies of each) and the two proteins may associate together as a complex. The glucose transporter (band 4.5) had AB(H) activity and there are about 5 x 10(5) copies/red cell. Several polypeptides associate together to form the Rh complex. The major components of this complex (abundance 1-2 x 10(5) copies/red cell) are polypeptides of Mr 30,000, polypeptides of Mr 45,000-100,000 and Glycophorin B. The antigens of the Rh blood group system appear to be associated with the polypeptides of Mr 30,000 and those of Mr 45,000-100,000 (the latter also express AB(H) activity). Glycophorin B expresses the blood group 'N' antigen and the Ss antigens. Glycophorins C and D carry the Gerbich antigens and, together, these polypeptides comprise approximately 10(5) copies/red cell. The complete protein sequence of all the above-mentioned proteins is known, except for the Mr 30,000 and Mr 45,000-100,000 polypeptides of the Rh complex for which only partial sequences are available, and Glycophorin D, the sequence of which can be inferred from that of Glycophorin C. Several of the minor blood group active proteins at the red cell surface (abundance less than 1.2 x 10(4)/red cell) have been the subject of recent studies. The polypeptide expressing Cromer-related blood group antigens has been identified as decay-accelerating factor and that carrying the Ina/Inb antigens as CD44. The protein sequence of both of these proteins has been deduced form nucleotide sequencing. The polypeptides expressing Kell antigens, Lutheran antigens, Fy antigens, and LW antigens have also been identified and partially characterised.
Comparison of intracytoplasmic A particles and intracisternal A particles (1975)

Abstract Intracytoplasmic A particles and intracisternal A particles are associated with mouse tumors of various types, and both can coexist in the cytoplasm of the same cell. The designation of both as A particles is based on the recognition that they share morphological similarities. A comparison of purified isolates of these two particles reveals that the structural protein profiles are different, but that there is some antigenic crossreaction as demonstrated by immunodiffusion and complement fixation. This result does not appear to involve the major structural protein of intracisternal A particles, but may reflect the presence of common antigenic determinants located on minor proteins.
Computationally efficient and reliable fingerprint mosaicking on embedded hardware using minutiae (2004)

Fingerprint matching is a common technique for biometric authentication. Solid state sensors allow the use of fingerprint recognition in small sized embedded systems. The size of these sensors makes it necessary to store several impressions of the same finger to provide good coverage of the entire fingertip. In order to reduce memory requirements and matching time all these impressions can be fused into a single larger image. Memory constraints imposed by embedded computers prohibit the use of images. A fingerprint is therefore represented as a set of minutiae coordinates and minutiae angles. We present a two stage approach to combine two fingerprints. First, a RANSAC based method is used to determine a rigid transformation which roughly aligns the two fingerprints. Second, the transformation is optimised using a robust least median of squares solution. The reliability of the method is demonstrated on a large synthetic dataset and real fingerprint images. The computational complexity and memory requirements allow implementation of the algorithm on embedded hardware.