gebhart/patrepeval huggingface dataset:
1695: Initial Experience with Optical Coherence Tomography (OCT) During Laparoscopic and Robotic Prostatectomy (2007)

You have accessJournal of UrologyModerated Poster 52, Wednesday, May 23, 2007, 8:00 - 10:00 am1 Apr 20071695: Initial Experience with Optical Coherence Tomography (OCT) During Laparoscopic and Robotic Prostatectomy Monish Aron, Jihad H. Kaouk, Jose R. Colombo, Nicholas J. Hegarty, Georges-Pascal Haber, Benjamin I. Chung, Mike M. Nguyen, Robert J. Stein, Jason M. Hafron, and Inderbir S. Gill Monish AronMonish Aron More articles by this author , Jihad H. KaoukJihad H. Kaouk More articles by this author , Jose R. ColomboJose R. Colombo More articles by this author , Nicholas J. HegartyNicholas J. Hegarty More articles by this author , Georges-Pascal HaberGeorges-Pascal Haber More articles by this author , Benjamin I. ChungBenjamin I. Chung More articles by this author , Mike M. NguyenMike M. Nguyen More articles by this author , Robert J. SteinRobert J. Stein More articles by this author , Jason M. HafronJason M. Hafron More articles by this author , and Inderbir S. GillInderbir S. Gill More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(18)31883-4AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "1695: Initial Experience with Optical Coherence Tomography (OCT) During Laparoscopic and Robotic Prostatectomy." The Journal of Urology, 177(4S), p. 563 © 2016 by American Urological AssociationFiguresReferencesRelatedDetails Volume 177Issue 4SApril 2007Page: 563 Advertisement Copyright & Permissions© 2016 by American Urological AssociationMetricsAuthor Information Monish Aron More articles by this author Jihad H. Kaouk More articles by this author Jose R. Colombo More articles by this author Nicholas J. Hegarty More articles by this author Georges-Pascal Haber More articles by this author Benjamin I. Chung More articles by this author Mike M. Nguyen More articles by this author Robert J. Stein More articles by this author Jason M. Hafron More articles by this author Inderbir S. Gill More articles by this author Expand All Advertisement PDF downloadLoading ...
Tackling the Anglophones’ free ride (2007)

In science and in all other domains that require communication across borders, we need one lingua franca, and this lingua franca will be English. The adoption of the native language of some as everyone’s lingua franca unavoidably raises a problem of justice in various senses. One of these is cooperative justice, the fair distribution of the cost of producing a public good. This article proposes a criterion of fair burden sharing — proportionality of cost to benefit — and explores its policy implications. Does this criterion require a linguistic tax on the native speakers of the lingua franca in order to subsidize the learning of it by all others? If so, how high should the subsidy be, and should it be pitched at the same per capita level for all learning communities? If not, is there an alternative way of implementing a fair compensation for the free riding of lingua franca natives on everyone else’s learning? Among the article’s conclusions are that fair subsidies would need to be directed disproportionately to the Chinese — even abstracting from possible differences in the difficulty of learning English — and that more hopes should be focused on the compensatory poaching of the web than on anything resembling a linguistic tax.
Isolation and Structure Elucidation by LC-DAD-MS and LC-DAD-SPE-NMR of Cyclopeptide Alkaloids from the Roots of <i>Ziziphus oxyphylla</i> and Evaluation of Their Antiplasmodial Activity (2016)

Nine cyclopeptide alkaloids (1-9), of which five (compounds 2, 3, 5, 8, and 9) are described herein for the first time, were isolated from roots of Ziziphus oxyphylla by means of conventional separation methods as well as semipreparative HPLC with DAD and ESIMS detection and LC-DAD-SPE-NMR. Structure elucidation was done by spectroscopic means. Nummularine-R (1), a previously known constituent from this species, was isolated along with its new derivatives O-desmethylnummularine-R (2) and O-desmethylnummularine-R N-oxide (3). In addition, the known compounds hemsine-A (4) and ramosine-A (6), as well as hemsine-A N-oxide (5), were isolated. Moreover, oxyphylline-C (7), a known constituent of Z. oxyphylla stems, was obtained, and two new compounds were identified, oxyphyllines-E (8) and -F (9). Just like oxyphylline-C, oxyphyllines-E and -F belong to the relatively rare class of neutral cyclopeptide alkaloids. The antiplasmodial activity and cytotoxicity of compounds 1, 2, 4, 6, and 9 were evaluated, and the most promising activity was found for O-desmethylnummularine-R (2), which exhibited an IC<sub>50</sub> value of 3.2 ± 2.6 μM against Plasmodium falciparum K1, whereas an IC<sub>50</sub> value of >64.0 μM was evident for its cytotoxicity against MRC-5 cells.
Impact of Material Management on Productivity—A Case Study (1989)

Recent CII research has indicated that formal material management programs have the potential to yield significant construction cost savings, yet small‐ and medium‐sized commercial contractors may not feel that an integrated material management program is cost effective. The objective of this paper is to quantify the adverse impacts of ineffective material management practices. Data collected as part of an ongoing construction productivity study is used to analyze and compare the effects of material management practices on two steel erection projects. Rules of credit were applied to calculate the daily output. Adverse conditions caused by the lack of an effective material management program are identified, and the days on which the conditions occurred are noted. For these days, the actual daily productivity is compared with the expected productivity to determine the number of work‐hours lost. The cost impact is compared to the cost of effective material management. The results show a benefits/cost ratio of 5.7, favoring greater attention to material management.
Lack of correlation between surface and interfacial activities of saponins and their hemolytic properties. (1999)

For a series of model compounds (digitonin, aescine, tomatine, stevioside and ginsenoside Rg1) it was demonstrated that neither the surface nor the interfacial tension (n-decane/water) lowering properties of saponins can be correlated with their ability to induce hemolysis. Furthermore, no correlation was observed between the surface and interfacial activities of saponins and their hemolytic properties.
Differential Response of Human and Mouse Dendritic Cells to VEGF Determines Interspecies Discrepancies in Tumor-Mediated Th1/Th2 Polarity Shift (2011)

Whereas humans with metastatic cancer demonstrate dysregulated immune polarity in response to excess plasma VEGF, tumor mice do not. This appears to be due to differences in APC responses to VEGF stimulation. Differential immune effects of VEGF may represent a key species difference in the context of translation of preclinical cancer immunotherapeutics into early clinical testing.
Cosmic Microwave Background science from Dome C (2009)

We summarize the results of the Cosmic Microwave Background (CMB) working group of the ARENA project. The focus has been on precision measurements of CMB polarization (looking for the echoes of cosmological inflation) and high angular resolution CMB measurements (looking for Sunyaev Zeldovich effect in distant clusters of Galaxies, to probe the evolution of the Universe, Dark Matter and Dark Energy). For both projects the Dome C site represents the best choice worldwide.
Topographic antigenic determinants on cytochrome c. Immunoadsorbent separation of the rabbit antibody populations directed against horse cytochrome. (1979)

Seven populations of site-specific antibodies were isolated from each of three sera of rabbits immunized against glutaraldehyde-polymerized horse cytochrome c. The antibodies were separated using an immunoadsorption scheme which employed the following cytochromes c: horse, beef, guanaco, rabbit, mouse testicular, pigeon, and the cyanogen-bromide cleaved fragment of the rabbit protein containing residues 1 to 65. The monovalent, antigen-binding fragments of the antibodies (Fab') gave 1:1 stoichiometries with native horse cytochrome c in fluorescence quenching assays. Cross-reactivities with heterologous cytochromes c using fluorescence quenching and a modified Farr assay demonstrated that the antigenic determinants are situated around residues 44, 60, and 89/92, four of the six amino acid sequence positions where horse and rabbit cytochromes c differ. The remaining two differences occur at residues 47 and 62. The apparent lack of immunogenicity of these two substitutions may result from the presence of the more immunogenic residues 44 and 60 nearby. Of the seven antibody populations isolated, four were shown to bind in the region of residues 89 and 92. Since several cytochromes c have amino acid sequence differences from the horse protein at either of these two residue positions, it was possible to fractionate the antibodies directed against this complex site on the basis of subtle specificity differences between them. Two antibody populations bind in the region of residue 44. One of these is specific for proline at that position, while the other antibody population also binds to cytochrome c containing glutamic acid at position 44. The remaining antibody population binds in the region of the lysine residue at position 60. Each of the seven site-specific antibody populations binds effectively to any cytochrome c having a suitable amino acid sequence in the antigenic determinant regardless of any residue differences from the immunogen outside of that area. It was also demonstrated that these seven antibody populations represent the totality of the antibodies elicited in rabbits against horse cytochrome c, since the immunoadsorbants bound all the antibodies specific for the native protein. Furthermore, the rabbit antisera contained no other antibody population that could bind to the conformationally disturbed, cyanogen bromide-cleaved fragment of horse cytochrome c containing residues 1 to 65, making it appear that there were no antibodies elicited against a "processed" form of cytochrome c.
Characterization of high-lysine barley genotypes (2008)

The lysine increase caused by single recessive genes is governed by two mechanisms in high-lysine barley mutants: either a decrease of the lysine-poor prolamins is compensated for by increased amounts of free lysine and non-prolamin proteins, or specific lysine-rich proteins are increased. One approach for obtaining an enhanced lysine content in the barley seed has been to combine high-lysine genes from each type. Herewith an increased lysine content has been achieved by an interactive effect of the high-lysine genes. In these combinations the glutelin proteins contribute with the greatest proportion of total seed lysine. Rat nitrogen balance tests show that the nutritional quality is improved to meet the essential amino acid requirement by man as well as monogastric animals. The grain weight and, thus, the grain yield of these high-lysine combinations are, however, reduced compared to standard varieties. An impaired synthesis of storage proteins (prolamins) and of starch can partly explain the lowered grain weight. By selecting for genetic backgrounds that interact harmoniously with the high-lysine genes the lowered grain yield might be overcome. Lysine screening methods are evaluated and divided into two groups, those detecting the lysine increase directly, and those indicating the lysine increase by measuring other properties.
High quality extremely thin SOI fabricated by facilitated ion-cut with H-trapping effect (2016)

High-quality strain-relaxed extremely thin silicon-on-insulator (ETSOI) has been fabricated by using H-trapping and etch-stop process in the H-implanted Si/Si0.70Ge0.30/Si/B-doped Si0.70Ge0.30/Si heterostructure. Compared to conventional ion-cut process, the combination of ultrathin SiGe interlayer with boron doping can significantly decrease the critical hydrogen implantation dosage needed for layer transfer by improving H-trapping efficiency. During subsequent annealing process, implanted H preferentially agglomerates at the trapping centers and induces long microcracks at the B-doped Si0.70Ge0.30/Si interface as well as in the near-interface region. The selective etch-stop process was used to remove residual Si/SiGe layers to expose a strain-relaxed Si device layer with a smooth surface morphology. These results demonstrate facilitated ion-cut as a promising approach for fabricating high crystalline quality ETSOI substrate and further offer a potential solution for scaling planar complementary metal–oxide–semiconductor to 22 nm node and beyond.
Investigation of<i>in vitro</i>biocompatibility of novel pentablock copolymers for gene delivery (2006)

Novel pentablock copolymers of poly(diethylaminoethylmethacrylate) (PDEAEM), poly(ethylene oxide) (PEO), and poly(propylene oxide) (PPO), (PDEAEM-b-PEO-b-PPO-b-PEO-b-PDEAEM), were synthesized as vectors for gene delivery, and were tested for their biocompatibility on SKOV3 (human ovarian carcinoma) and A431 (human epidermoid cancer) cell lines under different in vitro conditions using various assays to elucidate the mechanism of cell death. These copolymers form micelles in aqueous solutions and can be tuned for their cytotoxicity by tailoring the weight percentage of their cationic component, PDEAEM. Copolymers with higher PDEAEM content were found to be more cytotoxic, though their polyplexes were less toxic than the polycations alone. Pentablock copolymers displayed higher cell viability than commercially available ExGen 500 at similar N:P ratios. While cell death with ExGen was found to be accompanied by an early loss of cell membrane integrity, pentablock copolymers caused very little membrane leakage. Caspase-3/7 assay confirmed that none of these polymers induced apoptosis in the cells. These pentablock copolymers form thermo-reversible gels at physiological temperatures, thereby enabling controlled gene delivery. Toxicity of the polymer gels was tested using an agarose-matrix, simulating an in vivo tumor model where injected polyplex gels would dissolve to release polyplexes, diffusing through tumor mass to reach the target cells. Twenty five weight percent of copolymer gels were found to be nontoxic or mildly cytotoxic after 24 h incubation. Transfection efficiency of the copolymers was found to be critically correlated to cytotoxicity and depended on DNA dose, polymer concentration, and N:P ratios. Transgene expression obtained was comparable to that of ExGen, but ExGen exhibited greater cell death.
Recovery of Coal fines from Rejects byColumn Flotation (2000)

Investigations were carried out using column flotation to recover coking coal fines from the tailings generated at flotation plant of one of theoperating washeries. Columns of different diameter designed and developed by RRL, Bhubaneswar were used in these studies. Washabilitiy
studies indicated that the tailings have the potential to yield 60% of clean coal at 15.0% ash level. Flotation studies in cell indicated thata product with 16% ash can be obtained at 50% yield from these tailings. Results of column flotation had indicated that the performance
of column is superior to cell and close to washability data. Most of the coal values being rejected presently can be recovered by using theflotation column. The results obtained by 100 mm and 220 mm diameter laboratory columns could be reproduced on pilot column of 1000 mm diameter, confirming the validity of design and scale up criteria.
Fabrication of vertically aligned ferroelectric polyvinylidene fluoride mesoscale rod arrays (2013)

ABSTRACT We have fabricated vertically aligned ferroelectric PVDF mesoscale rod arrays comprising β and γ phases using a 200 nm diameter anodized aluminum oxide (AAO) as the porous template. We could synthesize the ferroelectric phase in mesoscale rod forms by combining the well‐established recipe for crystallizing the β phase using dimethyl sulfoxide (DMSO) at low temperature and template‐guided infiltration processing for the rods using AAO. We measured the dimensions of the PVDF rods by scanning electron microscopy and identified the polymorph phases by X‐ray diffraction and Fourier transform infrared spectroscopy. The length of the rods varied from 3.82 μm to 1.09 μm and the diameter from 232 nm to 287 nm when the volume ratio between DMSO and acetone changed from 5 : 5 to 10 : 0. We obtained well‐defined piezoresponse hysteresis loops for all rods with remnant piezoresponse ranging from 2.12 pm/V to 5.04 pm/V and coercive voltage ranging from 2.29 V to 2.71 V using piezoresponse force microscopy. Our results serve as a processing platform for flexible electronic devices that need high capacitance and piezoelectric functionalities such as flexible memory devices or body energy harvesting devices for intelligent systems. © 2013 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 130: 3842–3848, 2013
Arachidonic Acid Metabolites on Renin and Vascular Smooth Muscle Cell Growth (1996)

The interaction of hormones, growth factors, or cytokines to their specific cell surface receptors can lead to the stimulation of a cascade of biochemical events including the activation of several phospholipases which in turn can result in the release of several lipid second messengers (1) as outlined. Thus, the action of angiotensin II (AII) or other vascular smooth muscle cell (VSMC) growth factors can activate one or more phospholipases, phosphoinositide phospholipase C (PI-PLC), phosphatidylcholine-specific PLC (PC-PLC), or phospholipase D (PLD). This process results in the formation of the second messengers inositol trisphosphate (IP3), which leads to calcium (Ca2+) mobilization from intracellular stores, as well as diacylglycerol (DAG) which in turn can activate the Ca2+- and phospholipid-sensitive protein kinase C (PKC) (2-5). It has been suggested that the cellular response to AII is obtained by the temporal integration of the IP3/Ca2+-calmodulin branch responsible for the initial transient response and the DAG/PKC branch responsible for the sustained phase of All action (6). DAG is also a rich source of AA that can be released by the action of the enzyme DAG lipase (7) whereas the enzyme DAG-kinase can convert DAG to phosphatidic acid.
Low Vitamin D Levels Are Associated With Need For Surgical Correction In Pediatric Fractures (2015)

BACKGROUND: There is growing concern over a relationship between severity of pediatric fractures and low Vitamin D [25-hydroxyvitaminD, 25(OH)D] status. OBJECTIVE: Compare 25(OH)D levels and lifestyle of children with fractures to controls. Determine if 25(OH)D levels are associated with fractures and what the 25(OH)D fragility fracture threshold is within the fracture group. DESIGN/METHODS: Pediatric fracture and community controls were included. Bone health survey and medical record data was analyzed. Univariate and multivariable ordinal regression analyses were performed. Fractures were placed into groups using the Abbreviated Injury Score (AIS). AIS scores get progressively worse starting at AIS 1. AIS 3 were fractures requiring surgery. RESULTS: 369 fracture patients and 662 controls ≤ 18 years were included. Fracture and control groups’ 25(OH)D levels were not statistically different. Fracture group had mean 25(OH)D of 27.5 ± 8.9 vs 27.4 ± 9.1 in controls (p=0.914). However, among fracture patients, those with surgical fracture (AIS 3) had lower 25(OH)D levels (24.6) vs. nonsurgical fractures (AIS 1 & 2 with mean 30.0 and 28.3, respectively, p=0.001). The bone health survey found an association between increased outdoor play time and AIS fracture severity 3 (p=0.042). Adjusted odds ratios (OR) for Vitamin D levels on surgical fracture were calculated. Patients who had 25(OH)D <12 ng/mL were 20 times more likely to have a surgical fracture (OR 21.4, 95% CI 0.9-532, p=0.062). If 25(OH)D was <20ng/mL, the risk of surgical fracture was 3.5 times more likely (OR 3.5, 95% CI: 1.4-9.0, p=0.007). Patients who were <30ng/mL in 25(OH)D levels were twice as likely to have surgical fracture (OR 2.2, 95% CI: 1.0-4.7, p=0.059). Age, sex, and BMI were not found to be significant factors for AIS severity in this study. CLINICAL RELEVANCE: While the occurrence of a pediatric fracture was not associated with 25(OH)D levels in this study, kids with deficient Vitamin D levels appear to be at risk for more severe fractures. Ideal target serum level for 25(OH)D should be least 30ng/mL. Duration of outdoor play appears to be associated with more severe fracture risk. Future studies should investigate if this is due to increased exposure time to more at-risk activities while outdoors.
Crystal and magnetic structure of<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mrow><mml:msub><mml:mrow><mml:mi mathvariant="normal">Ca</mml:mi></mml:mrow><mml:mrow><mml:mn>2</mml:mn></mml:mrow></mml:msub></mml:mrow><mml:mrow><mml:msub><mml:mrow><mml:mi mathvariant="normal">RuO</mml:mi></mml:mrow><mml:mrow><mml:mn>4</mml:mn></mml:mrow></mml:msub></mml:mrow><mml:mo>:</mml:mo></mml:math>Magnetoelastic coupling and the metal-insulator transition (1998)

The crystal and magnetic structure of ${\mathrm{Ca}}_{2}{\mathrm{RuO}}_{4}$ (CRO) has been studied by powder neutron diffraction. CRO was synthesized in two different modifications (stoichiometric and containing excess oxygen) whose crystal structures are, in spite of strong differences in the lattice constants, closely related. Both structures are derived from the ideal ${\mathrm{K}}_{2}{\mathrm{NiF}}_{4}$ structure type by a rotation of the ${\mathrm{RuO}}_{6}$ octahedra around the long axis, combined with a tilt around an axis lying in the ${\mathrm{RuO}}_{2}$ plane. The orientation of the tilt axis seems to distinguish the two room-temperature symmetries; the excess oygen compound is characterized by a smaller tilt angle and shorter Ru-O in-plane bond distances. Stoichiometric CRO undergoes large structural changes on cooling, though no symmetry change was detected. In contrast, the excess oxygen containing compound undergoes a first-order structural phase transition accompanied by a change from metallic to insulating behavior in the electric resistivity. Both compounds exhibit antiferromagnetic order below 110--150 K; for the stoichiometric sample, the onset of magnetic order is associated with several structural anomalies.