gebhart/patrepeval huggingface dataset:
Evaluation of a five-antigen ELISA for diagnosis of tuberculosis in cattle and Cervidae (1996)

Results suggest that the 5-antigen ELISA would not be a good test for tuberculosis, especially in cattle, if used alone. However, when results of the ELISA and tuberculin test were interpreted in parallel, sensitivity of the combination was greater than sensitivity of either test alone. Similarly, when results of the 2 tests were interpreted in series, specificity of the combination was greater than specificity of either test alone.
Career Advancement Obstacles for Women in the Foodservice Industry (1996)

ABSTRACT While the number of females entering the management ranks of the foodservice industry is increasing, women continue to face obstacles not common to their male counterparts. The authors explore issues such as inequality in pay, stereotypes faced by women, women's responsibilities as primary family manager, the need for role models, and sexual harassment. These issues stymie the growth potential of women in foodservice management.
A New Aptameric Biosensor for Cocaine Based on Surface‐Enhanced Raman Scattering Spectroscopy (2008)

The present study reports the proof of principle of a reagentless aptameric sensor based on surface-enhanced Raman scattering (SERS) spectroscopy with "signal-on" architecture using a model target of cocaine. This new aptameric sensor is based on the conformational change of the surface-tethered aptamer on a binding target that draws a certain Raman reporter in close proximity to the SERS substrate, thereby increasing the Raman scattering signal due to the local enhancement effect of SERS. To improve the response performance, the sensor is fabricated from a cocaine-templated mixed self-assembly of a 3'-terminal tetramethylrhodamine (TMR)-labeled DNA aptamer on a silver colloid film by means of an alkanethiol moiety at the 5' end. This immobilization strategy optimizes the orientation of the aptamer on the surface and facilitates the folding on the binding target. Under optimized assay conditions, one can determine cocaine at a concentration of 1 muM, which compares favorably with analogous aptameric sensors based on electrochemical and fluorescence techniques. The sensor can be readily regenerated by being washed with a buffer. These results suggest that the SERS-based transducer might create a new dimension for future development of aptameric sensors for sensitive determination in biochemical and biomedical studies.
Expression of phosphatidylserine (PS) on wild‐type and Gerbich variant erythrocytes following glycophorin‐C (GPC) ligation (2005)

Glycophorin-C (GPC) is a 40 kDa glycoprotein expressed on erythrocytes and is a receptor for the malarial parasite Plasmodium falciparum to invade these cells. A link between GPC binding (ligation) and phosphatidylserine (PS) expression on erythrocytes has been suggested by its appearance on P. falciparum-infected erythrocytes. Phosphatidylserine expression has also been shown to be a marker of cellular death in a number of biological pathways including some in erythrocytes. Using Annexin V binding, we demonstrated that ligation of GPC with mouse mAb (BRIC-10) induced PS expression on normal erythrocytes. Phosphatidylserine exposure was prevented following tryptic digestion of intact erythrocytes. In addition, GPC variant phenotypes Yus (Delta exon 2) and Gerbich (Delta exon 3), which express a truncated extracellular domain, did not express PS following BRIC-10 binding, whereas PS was exposed on Ls(a) erythrocytes (duplication of exon 3). GPC ligation was also shown to result in a concomitant loss of erythrocyte viability in wild-type erythrocytes after 24 h in vitro. These results identify a potential pathway linking GPC to PS exposure on erythrocytes that may have a role in regulating red cell turnover. Further characterization of this pathway may also identify new targets for the treatment of P. falciparum malaria.
Observation of room temperature negative differential resistance in multi-layer heterostructures of quantum dots and conducting polymers (2010)

Multi-layer heterostructure negative differential resistance devices based on poly-[2-methoxy-5-(2'-ethyl-hexyloxy)-1,4-phenylenevinylene] (MEH-PPV) conducting polymer and CdSe quantum dots is reported. The conducting polymer MEH-PPV acts as a barrier while CdSe quantum dots form the well layer. The devices exhibit negative differential resistance (NDR) at low voltages. For these devices, strong negative differential resistance is observed at room temperature. A maximum value of 51 for the peak-to-valley ratio of current is reported. Tunneling of electrons through the discrete quantum confined states in the CdSe quantum dots is believed to be responsible for the multiple peaks observed in the I-V measurement. Depending on the observed NDR signature, operating mechanisms are explored based on resonant tunneling and Coulomb blockade effects.
An essential role for mitogen‐activated protein kinases, ERKs, in preventing heat‐induced cell death (1999)

Stimulation of mitogen-activated protein kinases (MAPKs) or extracellular signal regulated protein kinases (ERKs) after exposure of mammalian cells to ultraviolet (UV) and X-irradiation occurs through activation of receptor tyrosine kinases via Ras/Raf/Mek/ERKs cascade. This activation of MAPKs is proposed to play a role in the replacement of damaged proteins during these stresses. Heat shock also activates MAPKs; however, the signaling cascade and the biochemical and physiological links between activation by heat and downstream effects are unknown. In this report we demonstrate that, unlike irradiation, heat induces MAPKs through ceramide metabolism to sphingosine with stimulation of Raf-1 protein kinase. The activation of MAPKs by heat does not occur in all cell types, because the step(s) downstream of ceramide to activation of Raf-1 protein kinase is missing in myeloid leukemic cells such as HL-60, U937, and K562, while it is present in NIH3T3 fibroblasts. Heat-induced MAPK activation may enhance the ability of cells to survive a severe heat shock. Blocking 60–70% of the activity of MAPK (ERK1) by stable overexpression of the dominant negative allele ERK1-KR renders NIH3T3 and K562 cells up to 100-fold more sensitive to cytotoxic effects of heat. Conversely, NIH3T3 and K562 cells stably overexpressing the wild-type ERK1 develop resistance to killing by heat. These results suggest that increased thermal sensitivity of leukemic cells to thermal stress or other cancer therapy regimens could be attributable to lack of pertinent activation of the MAPK pathway by such stresses. J. Cell. Biochem. 74:648–662, 1999. © 1999 Wiley-Liss, Inc.
Synthesis of polymer–inorganic hybrid nanoparticles <i>via</i> radical polymerization initiated by surface‐immobilized photoiniferter (2003)

Abstract Polymer–inorganic hybrid nanoparticles were prepared through radical photo‐polymerization of methyl methacrylate initiated by N,N ‐diethyldithiocarbamyl surface functionalized silica nanoparticles under UV irradiation at ambient temperature. IR analysis and UV spectroscopy confirmed the occurrence of Et 2 NCS 2 —end groups on the resulting poly(methyl methacrylate), and the morphology of these hybrid nanoparticles was observed directly by means of tapping mode atomic force microscopy (AFM). Copyright © 2003 Society of Chemical Industry
Consultant pharmacist drug therapy recommendations from monthly drug regimen reviews in a geriatric nursing facility: a two-year study and cost analysis. (1997)

Geriatric long-term care patients appear to have numerous drug-related problems (DRPs) requiring unsolicited consultations, especially adverse drug reactions. Acceptance of consultant pharmacist recommendations may influence cost of overall care.
Comprehensive planning of robotic therapy and assessment of task-oriented functions via improved QFD applicable to hand rehabilitation (2010)

A successful implementation of any effective rehabilitation process using robotics systems must consider the issues in both clinical and engineering. Although many recent robotics rehabilitation works involve interdisciplinary teams with engineers and clinicians, there seems to be a gap between the engineers and the clinical groups. Useful and important results achieved in the clinical groups are not widely-received in the robotics community. Parts of the reason might lie with the complexity of the unfamiliar clinical topics and practical issues to engineers. On the other hand, many engineering works and results documented do not seem to focus on the crucial clinical problems. To this end, the present work aims to close the gap, as much as we could, by applying clinical aspects to robotics rehabilitation system via an improved quality function deployment (QFD) template based on effective rehabilitation outcome. The objective is to promote and enhance effective hand rehabilitation process by virtue of the proposed programme planning and assessment of hand functionality through clinical trials. The improved QFD template with main components can be extended to other clinical-based robotics rehabilitation works.
Respiratory viral infection predisposing for bacterial disease: a concise review (1999)

Although bacterial superinfection in viral respiratory disease is a clinically well documented phenomenon, the pathogenic mechanisms are still poorly understood. Recent studies have revealed some of the mechanisms involved. Physical damage to respiratory cells as a result of viral infection may lead to opportunistic adherence of bacteria. Enhanced bacterial adherence by specific mechanisms has been documented for respiratory cells infected with influenza A virus, respiratory syncytial virus and adenovirus in both in vitro and in vivo models. To date, results of various experimental studies indicate that different mechanisms for increased bacterial adherence induced by viruses are operating for specific viral-bacterial combinations. In the present review, a number of key findings obtained during the past two decades is presented and discussed.
Defect prediction metrics for infrastructure as code scripts in DevOps (2018)

Use of infrastructure as code (IaC) scripts helps software teams manage their configuration and infrastructure automatically. Information technology (IT) organizations use IaC scripts to create and manage automated deployment pipelines to deliver services rapidly. IaC scripts can be defective, resulting in dire consequences, such as creating wide-scale service outages for end-users. Prediction of defective IaC scripts can help teams to mitigate defects in these scripts by prioritizing their inspection efforts. The goal of this paper is to help software practitioners in prioritizing their inspection efforts for infrastructure as code (IaC) scripts by proposing defect prediction model-related metrics. IaC scripts use domain specific languages (DSL) that are fundamentally different from object-oriented programming (OOP) languages. Hence, the OOP-based metrics that researchers used in defect prediction might not be applicable for IaC scripts. We apply Constructivist Grounded Theory (CGT) on defect-related commits mined from version control systems to identify metrics suitable for IaC scripts. By applying CGT, we identify 18 metrics. Of these metrics, 13 are related to IaC, for example, count of string occurrences in a script. Four of the identified metrics are related to churn, and one metric is lines of code.
Thermodynamics and Magnetism of YCo5 Compound Doped with Fe and Ni: An Ab Initio Study (2020)

YCo5 permanent magnet exhibits high uniaxial magnetocrystalline anisotropy energy and has a high Curie temperature. These are good properties for a permanent magnet, but YCo5 has a low energy product, which is notably insufficient for a permanent magnet. In order to improve the energy product in YCo5, we suggest replacing cobalt with iron, which has a much bigger magnetic moment. With a combination of density-functional-theory calculations and thermodynamic CALculation of PHAse Diagrams (CALPHAD) modeling, we show that a new magnet, YFe3(Ni1-xCox)2, is thermodynamically stable and exhibits an improved energy product without significant detrimental effects on the magnetocrystalline anisotropy energy or the Curie temperature.
Terphenyl Ligand Systems in Lanthanide Chemistry:  Synthesis and Structural Characterization of Two 2,6-Dimesitylphenyl Derivatives of Trivalent Ytterbium (1999)

The molecular structures of two 2,6-dimesitylphenyl derivatives of trivalent ytterbium are reported, representing first examples of organolanthanide complexes with a sterically demanding terphenyl ligand system as the only organic substituent at the metal center. For example, the molecular structure of a base adduct of DmpYbCl2 (shown) features a monomeric complex with a distorted octahedral coordination environment about the metal center.
Side effects of high pressure irrigation (1977)

The Journal of Trauma: Injury, Infection, and Critical Care: March 1977 - Volume 17 - Issue 3 - p 256
HIV-1 latency in actively dividing human T cell lines (2008)

We describe the development of a new in vitro model for HIV-1 latency and discuss the advantages of this system. The data suggest that HIV-1 proviral latency is not restricted to resting T cells, but rather an intrinsic property of the virus.
Tectonics of Northern Franklin Mountains and Colville Hills, District of Mackenzie, Canada: Regional Arctic Geology of Canada (1973)

The northern Franklin Mountains and the Colville Hills, District of Mackenzie, are a series of ridges of divergent trends separated by broad, mostly drift-covered valleys. Some ridges are supported by thrust plates, and others by asymmetric anticlines. These structures, which represent shortening of the sedimentary cover, record tangential compression. Despite a variety of structural trends, there is no evidence for more than one phase of compression. The structural province is characterized by enigmatic thrust reversals. Typically, one end of a range is underlain by a southwest-dipping fault and the other by a northeast-dipping fault. The abrupt transition takes place via a transverse fault which separates the opposing blocks, and which seems to require longitudinal shortening of the range in addition to the more obvious shortening perpendicular to it. Reversals along the trend of a particular range are inadequately explained, but the close geometric relation between reversals and transverse faults suggests an interrelated origin dependent on longitudinal shortening in conjunction with lateral shortening. Most of the northern Franklin Mountains appear to be floored by a decollement zone in shale and evaporite beds of the Cambrian Saline River Formation. Structures above the zone probably are accentuated by tectonic thickening of the Saline River Formation. The decollement is assumed to extend beneath the Colville Hills about 175-200 mi (280-320 km) northeast of the Mackenzie Mountain front. In the McConnell Range on the south and the Mackenzie Mountains on the southwest, the decollement zone must be at a lower stratigraphic level, because beds older than the Saline River Formation are exposed in structures.
Design of a lattice decoder for MIMO systems in FPGA (2004)

Hardware implementation of lattice decoding algorithms becomes a challenging task as the complexity of MIMO systems increases. This paper presents the design and implementation of a Schnorr-Euchner strategy based lattice decoder using an FPGA. This lattice decoding algorithm has high data dependency during the iterative closest lattice point search procedures. The parallelism of the algorithm is explored and efficient hardware architectures are developed with the decoding function on FPGA and the data preprocessing on DSP. The system prototype of the decoder shows that it supports 2.7 Mbits/s data rate on a Virtex2-1000 FPGA, and is about 4 times faster than a DSP-based lattice decoder. The bit error rate (BER) performance is also tested and verified with software simulation.
Compensation of chromatic dispersion and dispersion slope using a virtually imaged phased array (2002)

Chromatic dispersion produced by the virtually imaged phased array (VIPA) is discussed. A newly designed 3-dimensional mirror produces uniform dispersion for each WDM channel with a wide variable dispersion range. The VIPA with the mirror also produces dispersion slope by including a diffraction grating.
Cancer Immunotherapy Using Tumor Cryoablation (2013)

Cryoablation is increasingly being used as a primary treatment for localized cancers and as a salvage therapy for metastatic cancers. Anecdotal clinical reports and animal experiments have confirmed an induction of systemic antitumor immune response by tumor cryoablation. To capitalize on the stimulatory effects of cryoablation for cancer immunotherapy, this response must be intensified using other immunomodulatory agents. This article reviews the preclinical and clinical evidence and discusses the mechanism of the antitumor immune response generated by cryoablation. The rationale and evidence behind several immunotherapy approaches that can be combined with cryoablation to devise a cryoimmunotherapeutic strategy with a potential to impact the progression of metastatic disease are described.
Concentration-dependent influence of various cytochalasins and chaetoglobosins on the phalloidin-induced polymerization of G-actin in 0.6 M potassium iodide (1980)

Phalloidin, a bicyclic peptide from the poisonous Amanita phalloides mushroom, stimulates the viscosimetrically determined polymerization of G-actin to F-actin in 0.6 m potassium iodide, a medium in which spontaneous polymerization does not occur. The cytochalasins B, D, E, and G (CB, CD, etc.) and the chaetoglobosins A, B, C, E, F, and J (Ch-A, Ch-B, etc.) have been found to influence the rat of polymerization in different ways, depending on their chemical structure and concentrations applied. Class I cytotoxins, e.g., CB, CG, Ch-C, Ch-E, and Ch-F, which exert on F-actin a weak degradative power (DP, "Spudich effect"), increase the polymerization rate when present in a ratio of 4 mol to 1 mol of actin. Polymerization is slightly enhanced or retarded at molar ratios ranging from 0.04:1 to 0.4:1. Class III cytotoxins of strong degradative power, i.e., high affinity for actin, such as CE, Ch-B, and Ch-J, decrease the polymerization rate at a molar ratio of 4:1 during the first 30-40 min; however, they increase it at a molar ratio of 0.4:1. Members of class II (CD, Ch-A) exert an effect that can be interpreted as a combination of the effects of class I and class III cytotoxins. An explanation of this difference in behavior is offered on the basis of experiments on F-actin degradation by Ch-J and its reconstitution by phalloidin in the presence of Ch-J.
Increasing detection of polymerase chain reaction (PCR) by isolation of PCR products (IPCRp). (2005)

The IPCRp procedure can be accomplished in less than 20 minutes. Efficient isolation of the PCR products has two steps, washing and denaturation. It can increase the yield of targeted PCR product and increase the sensitivity of the detection platform.
Providing a More Successful Education Experience for Asian Hospitality Management Students Studying in Australia (2002)

ABSTRACT Economic necessity and political influence has resulted in many western universities striving to increase the number of international students choosing their institution. The consequences of increased numbers of international students has implications for teaching staff and domestic students. This research is focused on international students from Asia studying the Bachelor of Business (Hospitality Management) at The University of Queensland and is set in the context of those students' learning experience. Focusing on issues of teaching and learning styles, the research is based on the suggestion that Asian students have to make a substantial adjustment in terms of their learning styles in order to succeed in a Western University. The empirical research focuses on Asian students' motivation, choices and expectations of their learning experience in Australia and identifies difficulties those students have experienced. Insights of staff within the School of Tourism and Leisure Management at the University of Queensland are also discussed, particularly focusing on cultural issues. This article concludes with several recommendations concerning strategies that could be, and are being adopted by The University, academic staff and Asian students.
Genital Sensations in Persistent Genital Arousal Disorder: A Case for an Overarching Nosology of Genitopelvic Dysesthesias? (2018)

The proposed model can provide an important framework for conceptualizing conditions characterized by unpleasant genitopelvic sensations. A model such as this one can benefit highly misunderstood conditions that are questioned in terms of their legitimacy and severity-such as PGAD-by conceptualizing them as sensory disorders, which in turn can reduce stigma, unify research efforts, and potentially improve access to care. Pukall CF, Jackowich R, Mooney K, et al. Genital Sensations in Persistent Genital Arousal Disorder: A Case for an Overarching Nosology of Genitopelvic Dysesthesias? Sex Med Rev 2019;7:2-12.
Phase Shift Corrections for Infrared Interference Measurement of Epitaxial Layer Thickness (1966)

Under certain conditions of wavelength and substrate impurity level, correction factors were found to be necessary for the infrared interference method of measuring epitaxial layer thickness. A general theory has been developed which relates the index of refraction and extinction coefficient to physical properties of the semiconductor and the wavelength. From these constants, a phase change at the epitaxial layer‐substrate interface is calculated. This phase shift is shown to influence the measurement and a correction factor is derived.
Theory of the Detection of Two Modulated Waves by a Linear Rectifier (1933)

In this paper there is developed a mathematical analysis of the detection, by a linear rectifier, or two modulated waves. Solutions are obtained which are manageable over wide ranges of values of carrier ratio and degrees of modulation. These solutions are of greater applicability and are more convenient than those previously obtained, and give a full treatment of the action of an ideal linear rectifier under the action of two modulated waves. The development is first made in terms of the derivatives of zonal harmonics of an angle which is directly related to the phase difference between the carriers. As these derivatives are tabulated functions the solution is convenient. The solutions are limited by the condition that K <(1-M)/(1+m), K being the carrier ratio, M the degree of modulation of the stronger carrier, and m that of the weaker. Two methods of attack are developed one of which is applicable when K is small and M and m large, and the other when M and m are small and K large. The cases of identical and of different programs are both considered and a number of curves are given showing the magnitudes of various output frequency components under typical operating conditions. In the latter part of the paper the phase angle between the carriers is set equal to μt so that a beat note exists.