gebhart/patrepeval huggingface dataset:
Metal carbonyl chemistry. Part XV. Reactions of the dicarbonylbis-(triphenylphosphine)rhodate anion, [Rh(CO)<sub>2</sub>(PPh<sub>3</sub>)<sub>2</sub>]<sup>–</sup>, with some perfluoroaromatic compounds (1971)

The carbonylmetal anion [Rh(CO)2(PPh3)2]– has been shown to be a strong nucleophile of similar power to that of [(π-C5H5)Fe(CO)2]– or [(π-C5H5)Ru(CO)2]–. Its reactions with the compounds C6F6, C6F5X (X = CN or CO2Et), (NC)2C6F4, C5F5N, and 2-(NC)C5F4N to afford some new perfluoroaromatic rhodium(l) complexes are discussed.
Ras recruits mitotic exit regulator Lte1 to the bud cortex in budding yeast (2003)

ACdc25 family protein Lte1 (low temperature essential) is essential for mitotic exit at a lowered temperature and has been presumed to be a guanine nucleotide exchange factor (GEF) for a small GTPase Tem1, which is a key regulator of mitotic exit. We found that Lte1 physically associates with Ras2-GTP both in vivo and in vitro and that the Cdc25 homology domain (CHD) of Lte1 is essential for the interaction with Ras2. Furthermore, we found that the proper localization of Lte1 to the bud cortex is dependent on active Ras and that the overexpression of a derivative of Lte1 without the CHD suppresses defects in mitotic exit of a Deltalte1 mutant and a Deltaras1 Deltaras2 mutant. These results suggest that Lte1 is a downstream effector protein of Ras in mitotic exit and that the Ras GEF domain of Lte1 is not essential for mitotic exit but required for its localization.
Assessment of Sex Differences in the Initial Symptom Burden, Applied Treatment Strategy, and Quality of Life in Japanese Patients With Atrial Fibrillation (2019)

In contemporary Japanese clinical practice among unselected patients with AF, women were initially seen with greater QOL impairment, and the sex gap grew 1 year after presentation. The present study underscores the need for focused efforts to better understand and close this observed sex gap over the initial year of treatment for patients with AF.
Synthesis and behavior of Belite-Alite-Ye’elimite (BAY) cement (2016)

Póster en congreso científico
QoS-Aware Resource Discovery in Mobile Environments (2006)

In this chapter, we will address the problem of resource discovery that ensures sustained QoS (Quality of Service) for mobile applications. We present two aspects of the resource discovery problem: (i) static resource discovery that determines the best resources to service a request when it is initiated, (ii) dynamic resource reprovisioning that continues to find nearby resources as a mobile client moves arbitrarily. We explain the role of context information in effective resource discovery and discuss what constitutes relevant context information for mobile applications. By introducing a generalized mediation-based architecture, we show how context information is collected and applied to support static and dynamic resource discovery. We illustrate potential solutions to these issues through a case study that uses nearby grid resources to support mobile services.
Summary report: Working group 6 on {open_quotes}microwave sources{close_quotes} (1997)

This report summarizes the discussions of the Microwave Source Working Group during the Advanced Accelerator Concepts Workshops held October 13{endash}19, 1996 in the Granlibakken Conference Center at Lake Tahoe, California. Progress on rf sources being developed for linear colliders is reviewed. Possible choices for high-power rf sources at 34 GHz and 94 GHz for future colliders are examined. {copyright} {ital 1997 American Institute of Physics.}
Synthesis of (±)-Kopsinitarine E (2020)

Key words (±)-kopsinitarine E - kopsia alkaloid - Dieckmann-like condensation - semipinacol rearrangement - Mannich reaction
The Value of Intraoperative Histology in Predicting Infection in Patients Undergoing Revision Elbow Arthroplasty (2013)

Diagnostic level I. See Instructions for Authors for a complete description of levels of evidence.
Genomic adaptations to aquatic and aerial life in mayflies and the origin of insect wings (2020)

The evolution of winged insects revolutionized terrestrial ecosystems and led to the largest animal radiation on Earth. However, we still have an incomplete picture of the genomic changes that underlay this diversification. Mayflies, as one of the sister groups of all other winged insects, are key to understanding this radiation. Here, we describe the genome of the mayfly Cloeon dipterum and its gene expression throughout its aquatic and aerial life cycle and specific organs. We discover an expansion of odorant-binding-protein genes, some expressed specifically in breathing gills of aquatic nymphs, suggesting a novel sensory role for this organ. In contrast, flying adults use an enlarged opsin set in a sexually dimorphic manner, with some expressed only in males. Finally, we identify a set of wing-associated genes deeply conserved in the pterygote insects and find transcriptomic similarities between gills and wings, suggesting a common genetic program. Globally, this comprehensive genomic and transcriptomic study uncovers the genetic basis of key evolutionary adaptations in mayflies and winged insects.
Reclassification of Desulfovibrio desulfuricans Norway 4 as Desulfomicrobium norvegicum comb. nov. and Confirmation of Desulfomicrobium escambiense (corrig., Formerly "escambium") as a New Species in the Genus Desulfomicrobium (1997)

Desulfomicrobium escambiense, Desulfomicrobium baculatum, Desulfomicrobium apsheronum, and Desulfovibrio desulfuricans Norway 4 are closely related as determined by a 16S rRNA comparison (levels of relatedness, 0.976 to 0.997) and are distinct on the basis of levels of DNA-DNA similarity (11.1 to 27.4%), genomic restriction fragment length polymorphism patterns, and certain phenotypic characteristics. We proposed that Desulfovibrio desulfuricans Norway 4 be renamed Desulfomicrobium norvegicum comb. nov.
Nitric oxide formation in a lean, premixed-prevaporized jet A/air flame tube: An experimental and analytical study (1992)

An experimental and analytical study was performed on a lean, premixed-prevaporized Jet A/air flame tube. The NO(x) emissions were measured in a flame tube apparatus at inlet temperatures ranging from 755 to 866 K (900 to 1100 F), pressures from 10 to 15 atm, and equivalence ratios from 0.37 to 0.62. The data were then used in regressing an equation to predict the NO(x) production levels in combustors of similar design. Through an evaluation of parameters it was found that NO(x) is dependent on adiabatic flame temperature and combustion residence time, yet independent of pressure and inlet air temperature for the range of conditions studied. This equation was then applied to experimental data that were obtained from the literature, and a good correlation was achieved.
Organophosphazenes. 15. Reactions of hexafluorocyclotriphosphazene with tert- and n-butyllithium reagents (1982)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTOrganophosphazenes. 15. Reactions of hexafluorocyclotriphosphazene with tert- and n-butyllithium reagentsKolikkara Ramachandran and Christopher W. AllenCite this: J. Am. Chem. Soc. 1982, 104, 9, 2396–2399Publication Date (Print):May 1, 1982Publication History Published online1 May 2002Published inissue 1 May 1982https://pubs.acs.org/doi/10.1021/ja00373a011https://doi.org/10.1021/ja00373a011research-articleACS PublicationsRequest reuse permissionsArticle Views136Altmetric-Citations17LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
Prognostic significance of <i>GSTP1 and MGMT</i> hypermethylation in invasive ductal breast carcinoma patients. (2009)

Abstract Abstract #4053 Purpose: Methylation-mediated suppression of detoxification, DNA repair and tumor suppressor genes has been implicated in cancer development, by shifting cells from the normal cellular cycle to a state of high proliferation that favors tumor development and progression. The current study was designed to analyze the methylation status of these genes in sera of breast cancer patients and determine the correlation of promoter hypermethylation of these genes with disease prognosis and patient survival.&#x2028; Experimental design: To test the hypothesis that promoter methylation of GSTP1 and MGMT is associated with disease prognosis, the methylation status of these genes was analyzed in invasive ductal carcinoma tissues and corresponding sera of breast cancer patients and correlated with disease free survival of these patients.&#x2028; Results: Promoter methylation of GSTP1 and MGMT was observed in 25% and 38% of breast tumor tissues, respectively and in 23% and 35% of the corresponding sera of breast cancer patients. There was significant association between methylation of GSTP1 and advanced tumor stage. Patients harboring methylated GSTP1 were more likely to have disease progression and reduced overall survival compared with patients who did not have the methylated gene.&#x2028; Conclusion: GSTP1 methylation in tumor and sera may serve as a poor prognostic marker in patients with invasive ductal carcinoma. Citation Information: Cancer Res 2009;69(2 Suppl):Abstract nr 4053.
Characteristics of Red Palm Oil, a Carotene- and Vitamin E–rich Refined Oil for Food Uses (2000)

A novel process involving pretreatment of crude palm oil, followed by deacidification and deodorization using molecular distillation, can be used to produce a carotene-rich refined edible palm oil. the product is a refined red palm oil that meets standard refined edible oil specifications and retains up to 80% of the carotene and vitamin E originally present in the crude palm oil. the oil contains no less than 500 ppm carotene, 90% of which is present as α- and β-carotene. the vitamin E content is about 800 ppm, 70% of it in the form of tocotrienols (mainly as α-, β-, and γ-tocotrienols). Other valuable minor components present in this oil are ubiquinones and phytosterols. the process is also applicable for the commercial production of other natural vitamin-rich palm fractions, such as stearin, olein, and palm mid-fraction. Such products are currently available and can be used in various food applications, both as cooking media and as ingredients that enhance the appearance and nutritional value of foods.
Microbiome-Metabolome Responses to a High-Grain Diet Associated with the Hind-Gut Health of Goats (2017)

Studies on the effect of a high-concentrate (HC) diet on the hindgut microbiota and metabolome of ruminants are rarely reported. We used 454 pyrosequencing of 16S rDNA genes and gas chromatography–mass spectrometry to evaluate the effects of long-term feeding (HL) or short-term (HS) feeding of an HC diet on changes in bacterial microbiota and their metabolites in the hindgut, with Guanzhong goat as a ruminant model. Results indicated that an HC diet decreased bacterial diversity and induced metabolic disorder in the hindgut. The levels of lactate, endotoxin (lipopolysaccharide [LPS]), and volatile fatty acid concentrations were higher in the intestinal digesta of the HC goats than in those of the LC goats (P < 0.05). The level of beta-alanine decreased, whereas the levels of stigmasterol and quinic acid decreased in the cecal and colonic digesta of the HC goats. At the genus level, the abundance of Clostridium and Turicibacter was significantly increased in both the colonic and cecal digesta of the HC goats. Several potential relationships between metabolites and several microbial species were revealed in this study. The mRNA expression of the genes functionally associated with nutrients transport, including NHE2, NHE3, MCT1 and MCT4 were significantly downregulated in the colonic mucosa by the HC diet (P < 0.05). The expression levels of the genes related to the inflammatory response, including TLR4, MYD88, TNF-α and IL-1β were markedly upregulated in the cecal mucosa by the HC diet (P < 0.05). Our results indicate that an HC diet induces microbiota dysbiosis, metabolic disorders, and mucosal damage in the hindgut of goats.
Schwingungsenergieumverteilung in Lösung (1987)

Abstract Large molecules are vibrationally excited via resonant absorption of infrared picosecond pulses or via electronic absorption and subsequent rapid internal conversion. The relaxation of vibrational energy is monitored by a second light pulse which measures changes in the long‐wavelength tail of the electronic absorption. Very rapid intramolecular energy redistribution (τ inter < 2 ps) is observed, followed by intermolecular energy transfer to the surrounding ( t inter ∼ 10 ps).
Resistive synaptic interconnects for electronic neural networks (1987)

High-density, nonvolatile, associative electronic memories, based on neural network models, require large arrays of highly uniform, small-area, resistive (106–107 Ω) synaptic-feedback connections. Such passive, two-terminal resistors (very weak connections) are uncommon in the current very large scale integrated (VLSI) world. We report on the use of resistivity-tailored amorphous Ge1−xMx alloy (M=Al, Cu; 2≤x≤25 at. %) and Pt/Al2O3 cermet thin films as the resistive interconnects for the associative memories. Resistivity of the films is primarily controlled by their metal contents and deposition conditions. Arrays of highly uniform (±5%) interconnects, typically 10–20 μm long, 10 μm wide, and 0.1 μm thick, have been fabricated employing conventional photolithography. Suitability of the α-Ge:M and Pt/Al2O3 connections in the fault-tolerant, neural network memories is discussed.
Die Polymerisation von Lactamen. IV. Die anionische Copolymerisation von 6‐Caprolactam mit 8‐Caprylolactam (1974)

Abstract Es wurden die Bedingungen für die Herstellung homogener Gußstücke auf der Basis der Copolymeren aus 6‐Caprolactam und 8‐Caprololactam durch anionische adiabatische Tieftemperaturcopolymerisation beider Lactame unterhalb des Schmelzpunktes der Polymerprodukte (Katalysator: Natriumsalz der Lactame, Aktivator: N‐Acetyl‐6‐caprolactam) untersucht. Der Anteil von 8‐Caprylolactam im Copolymeren ist auf Konzentrationen maximal bis zu 30 Mol‐% beschränkt, und zwar wegen seiner hohen Polymerisationswärme und wegen der Abhängigkeit der Schmelztemperatur der Copolymeren vom Anteil beider Lactame; unter diesen Bedingungen kann keine Homopolymerisation von 8‐Caprylolactam vorgenommen werden. Die Schmelztemperatur der Copolymeren weist ein Minimum im Gebiet der äquimolaren Anteile beider Lactame auf. Ferner wurde die Temperaturabhängigkeit der spezifischen Wärme von 8‐Caprylolactam im Bereich von 100–226°C (C p =0,2543 + 0,0007 T) bestimmt. Die Gesamtgeschwindigkeit der anionischen Copolymerisation nimmt mit steigendem Gehalt an 8‐Caprylolactam im Einklang mit den Differenzen in der Geschwindigkeit der Homopolymerisation beider Lactame zu. Proportional mit dem zunehmenden Gehalt an 8‐Caprylolactam sinkt der Gehalt an mit Wasser extrahierbaren Anteilen im anionischen Copolymeren, ähnlich wie bei den durch hydrolytische Copolymerisation hergestellten Gleichgewichts‐Copolymerisaten.
Surgical Salvage of Bleeding Peptic Ulcers after Failed Therapeutic Endoscopy (2009)

With advances in therapeutic endoscopy, patients who developed failed endoscopic hemostasis are likely to be poor surgical candidates with multiple comorbidities. The approach to salvage surgery has inclined towards minimal surgery to hasten surgical hemostasis among these fragile patients.
Application of Immunosignatures for Diagnosis of Valley Fever (2014)

Valley fever (VF) is difficult to diagnose, partly because the symptoms of VF are confounded with those of other community-acquired pneumonias. Confirmatory diagnostics detect IgM and IgG antibodies against coccidioidal antigens via immunodiffusion (ID). The false-negative rate can be as high as 50% to 70%, with 5% of symptomatic patients never showing detectable antibody levels. In this study, we tested whether the immunosignature diagnostic can resolve VF false negatives. An immunosignature is the pattern of antibody binding to random-sequence peptides on a peptide microarray. A 10,000-peptide microarray was first used to determine whether valley fever patients can be distinguished from 3 other cohorts with similar infections. After determining the VF-specific peptides, a small 96-peptide diagnostic array was created and tested. The performances of the 10,000-peptide array and the 96-peptide diagnostic array were compared to that of the ID diagnostic standard. The 10,000-peptide microarray classified the VF samples from the other 3 infections with 98% accuracy. It also classified VF false-negative patients with 100% sensitivity in a blinded test set versus 28% sensitivity for ID. The immunosignature microarray has potential for simultaneously distinguishing valley fever patients from those with other fungal or bacterial infections. The same 10,000-peptide array can diagnose VF false-negative patients with 100% sensitivity. The smaller 96-peptide diagnostic array was less specific for diagnosing false negatives. We conclude that the performance of the immunosignature diagnostic exceeds that of the existing standard, and the immunosignature can distinguish related infections and might be used in lieu of existing diagnostics.
ICT and Privacy in Europe. Experiences from technology assessment of ICT and Privacy in seven different European countries. Final report October 16, 2006, European Parliamentary Technology Assessment network (EPTA) (2007)

This report is offered by the European Parliamentary Technology Assessment network (EPTA) as a contribution to the European debate and policy-making on privacy. It is based on 28 technology assessment projects carried out by the participating EPTA members. These projects have been reviewed and a cross-European synthesis has been made. From the analysis of the societal as well as technological developments we have derived conclusions and policy options.
Promoter-specific insulin-like growth factor 2 gene imprinting in human fetal liver and hepatoblastoma (1998)

Insulin-like growth factor 2 (IGF2) gene imprinting has been demonstrated to be promoter-specific, in that expression from the P1 promoter is biallelic whereas that from the P2-P4 promoters is monoallelic. In the present study, in order to investigate IGF2 gene imprinting status at the cellular level, allelic analysis was performed of IGF2 gene expression transcribed from the P1 and P3 promoters, using reverse transcription polymerase chain reaction (RT-PCR) on human fetal liver and hepatoblastoma. In situ hybridization was also undertaken, to obtain information about the cellular localization of transcripts expressed from the P1 and P3 promoters. The results indicated that transcripts expressed from the P1 and P3 promoters co-localized in the same fetal or neoplastic hepatocytes. These data should provide information regarding the molecular basis of genomic imprinting, suggesting that an imprint recognized for the differential expression may be strictly local and localized downstream of the IGF2 P1 promoter.
Elevated Umbilical Cord Ghrelin Concentrations in Small for Gestational Age Neonates (2003)

Ghrelin has orexigenic effects. It is present in umbilical cord plasma in full-term neonates, raising the prospect that ghrelin plays a role in fetal and neonatal energy balance. We measured ghrelin in small (SGA), appropriate (AGA), and large (LGA) for gestational age neonates and evaluated whether ghrelin levels are modulated by neonatal insulin and glucose concentrations. Plasma concentrations of ghrelin, insulin, and glucose were measured in cord blood sampled at birth in 123 SGA, AGA, and LGA neonates (gestational age, 24-41 wk) born to mothers with and without diabetes. Ghrelin was detected in samples from all infants. Its concentration was 40% higher in SGA neonates (mean +/- SD, 2436 +/- 657 pg/ml) compared with AGA (1738 +/- 380) and LGA (1723 +/- 269) neonates. There was a positive correlation between ghrelin and gestational age in AGA/LGA (r = 0.23; P < 0.05) and a negative correlation in SGA (r = -0.67; P < 0.005) neonates. Therefore, the difference in ghrelin between SGA and AGA/LGA neonates decreases with advancing gestational age. Birth weight z-score, maternal hypertension, and glucose concentrations were significant determinants of ghrelin concentrations. In conclusion, SGA neonates present with higher umbilical cord ghrelin plasma concentrations than AGA/LGA neonates. Ghrelin may play a physiological role in fetal adaptation to intrauterine malnutrition.
370 mW, 1.06 μm, CW TEM <sub>00</sub> output from an Nd:YAG laser rod end-pumped by a monolithic diode array (1987)

We report 370 mW CW output at 1.06 μm in the TEM∞ mode with 9.1% electrical to optical (wall-plug) conversion efficiency from an Nd:YAG laser rod end-pumped by a monolithic 100 μm-wide diode laser array.
Pipe Production Technology And Properties of X120 Linepipe (2003)

To provide a lower cost option for long distance gas transmission, X120 UOE linepipe has been developed. After development of heavy plate and basic seam welding technology, finite element models and forming tests in the UOE mill established the forming conditions and tooling design criteria to solve the problem of the large spring back that occurs during forming of the plate. To confirm X120 mass production technology, more than one hundred pipes were manufactured in a small-scale, commercial production run or “mini-roll.” The produced pipe generally met the dimensional tolerances and mechanical property targets, but improvements are planned for future runs. Field bending of the X120 pipe has been demonstrated, and the resistance to hydrogen embrittlement by cathodic protection has been confirmed.
High Winds of Neptune: A Possible Mechanism (1991)

Neptune receives only 1/900th of the earth's solar energy, but has wind speeds of nearly 600 meters per second. How the near-supersonic winds can be maintained has been a puzzle. A plausible mechanism, based on principles of angular momentum and energy conservation in conjunction with deep convection, leads to a regime of uniform angular momentum at low latitudes. In this model, the rapid retrograde winds observed are a manifestation of deep convection, and the high efficiency of the planet's heat engine is intrinsic from the room allowed at low latitudes for reversible processes, the high temperatures at which heat is added to the atmosphere, and the low temperatures at which heat is extracted.