gebhart/patrepeval huggingface dataset:
D2Taint: Differentiated and dynamic information flow tracking on smartphones for numerous data sources (2013)

With smartphones' meteoric growth in recent years, leaking sensitive information from them has become an increasingly critical issue. Such sensitive information can originate from smartphones themselves (e.g., location information) or from many Internet sources (e.g., bank accounts, emails). While prior work has demonstrated information flow tracking's (IFT's) effectiveness at detecting information leakage from smartphones, it can only handle a limited number of sensitive information sources. This paper presents a novel IFT tagging strategy using differentiated and dynamic tagging. We partition information sources into differentiated classes and store them in fixed-length tags. We adjust tag structure based on time-varying received information sources. Our tagging strategy enables us to track at runtime numerous information sources in multiple classes and rapidly detect information leakage from any of these sources. We design and implement D2Taint, an IFT system using our tagging strategy on real-world smartphones. We experimentally evaluate D2Taint's effectiveness with 84 real-world applications downloaded from Google Play. D2Taint reports that over 80% of them leak data to third-party destinations; 14% leak highly sensitive data. Our experimental evaluation using a standard benchmark tool illustrates D2Taint's effectiveness at handling many information sources on smartphones with moderate runtime and space overhead.
The advantage of mucosal immunization for polysaccharide‐specific memory responses in early life (2005)

The aim of vaccination is to rapidly elicit protective immunity and generate memory for sustained protection. We studied the induction and persistence of polysaccharide (PS)-specific memory in neonatal and infant mice primed with pneumococcal conjugate (Pnc1-TT) by assessing the response to native pneumococcal PS (PPS-1), the kinetics of the PPS-1-specific IgG response to a second Pnc1-TT dose and affinity maturation. A subcutaneous (s.c.) Pnc1-TT booster induced a rapid increase in PPS-1-specific IgG, indicating efficient priming for memory by a single dose of Pnc1-TT already at 1 week of age. High levels were maintained for >12 weeks. However, a PPS-1 booster induced no response in neonatal or infant mice. The adjuvant LT-K63 significantly enhanced the IgG response and affinity to Pnc1-TT by both the s.c. and the intranasal (i.n.) route in all age groups. In neonatal and infant mice, PPS-1 and LT-K63 induced a booster response only when given i.n. following either s.c. or i.n. priming with Pnc1-TT and LT-K63. In contrast, PPS-1 with or without LT-K63 administered s.c. compromised the ongoing PPS-1-specific response elicited in neonatal mice by either s.c. or i.n. priming with Pnc1-TT and LT-K63. These results demonstrate the advantage of the mucosal route for elicitation of PS-specific memory responses in early life.
Pore filling behavior of <scp>YSZ</scp> under <scp>CMAS</scp> attack: Implications for designing corrosion‐resistant thermal barrier coatings (2018)

Abstract To understand the pore filling behavior in thermal barrier coatings during calcium‐magnesium‐alumino‐silicate ( CMAS ) infiltration process, porous yttria‐stabilized zirconia pellets with different sizes of spherical pores were prepared to simulate thermal barrier coatings. The pores (D50 ranging from 6 to 77 μm) were introduced to the pellets using poly methyl methacrylate as pore forming agents. Then the pellets were sintered to remove the pore forming agents and to achieve a similar volume fraction of porosity with thermal barrier coatings. After CMAS infiltration, only some small pores in the CMAS ‐infiltrated zones were filled by CMAS , whereas all large pores (larger than 13 μm) remained unfilled; besides, the results also show that even open pores can resist filling by CMAS . The reason may relate to pore diameters; if the diameter of a pore is relatively large, the pore surface will not be completely wetted by liquid CMAS , the liquid meniscus will be discontinuous, and therefore the pore cannot be filled. The key insight gained from this study is that introducing “ CMAS ‐proof” pores into thermal barrier coatings may be a potential way to mitigate CMAS damage.
LOGO-Net: Large-scale Deep Logo Detection and Brand Recognition with Deep Region-based Convolutional Networks (2015)

Logo detection from images has many applications, particularly for brand recognition and intellectual property protection. Most existing studies for logo recognition and detection are based on small-scale datasets which are not comprehensive enough when exploring emerging deep learning techniques. In this paper, we introduce "LOGO-Net", a large-scale logo image database for logo detection and brand recognition from real-world product images. To facilitate research, LOGO-Net has two datasets: (i)"logos-18" consists of 18 logo classes, 10 brands, and 16,043 logo objects, and (ii) "logos-160" consists of 160 logo classes, 100 brands, and 130,608 logo objects. We describe the ideas and challenges for constructing such a large-scale database. Another key contribution of this work is to apply emerging deep learning techniques for logo detection and brand recognition tasks, and conduct extensive experiments by exploring several state-of-the-art deep region-based convolutional networks techniques for object detection tasks. The LOGO-net will be released at http://logo-net.org/
Estimation of traffic density from drone-based delivery in very low level urban airspace (2020)

Driven by rising consumer demand, interest is growing in the application of autonomous unmanned aerial vehicles (drones) for the last-mile delivery of small express packages and fast-food meals in cities. To be realised, this would require the Very Low Level (VLL) urban airspace to be able to cope with high traffic densities of commercial delivery drones. The potential benefits of such novel drone-based applications are a reduction of traffic congestion in cities, lower greenhouse gas emissions and more efficient transportation operations. To help realise this concept, programs such as U-Space, the unmanned traffic management system for Europe, are developing important services such as deconfliction management and dynamic capacity management. However, for several of these services, design choices will depend on how, and how extensive they will be used. It therefore becomes important to estimate how many delivery drones would operate in a typical city. This paper aims to provide an estimate by establishing a framework to determine the traffic demand for express drone-based package delivery of five European countries. In addition, a detailed case-study is presented for determining traffic density of express package drone delivery for Paris metropolitan area in order to assess the feasibility from a user's perspective. The paper also discusses the potential of fast-food meal delivery drones compared to traditional delivery modes for Paris. Results suggest that hourly traffic densities culminating from express package and fast-food meal delivery drones will exceed today's global commercial aircraft traffic of 10,000 per day by more than six-fold for just one potential metropolitan city.
Supply-side economics and the 2017 Tax Act (2018)

Several of the designers of the 2017 Tax Act were prominent as 'supply side advocates at the time of Reagan tax cuts during the 1980s.The economic argument for supply side tax rate reductions drew on a policy mix framework developed by Robert Mundell as early as 1962.Within that framework, the easy fiscal/ tight monetary policy solution was intended for circumstances of either pressure on reserves or the exchange rate (as during the Kennedy Administration) or of serious domestic inflation (as under the Carter and Reagan Administrations).Tax cuts in the US since the 1980s have not had the intended stimulus effects because neither the currency weakness nor inflationary preconditions have existed.Absent such conditions, tax rate reductions will generate either domestic over-heating or a redistribution of income to those in higher brackets.Any argument in favor of the 2017 Tax Act should not fall back on Mundell's policy mix advocacy.In contrast, the case for an easy fiscal/ tight money policy may have unexpected force in situations of fixed exchange rates, or where domestic monetary policy options are otherwise constrained or absent -as in Eurozone periphery countries.
Long Patch Base Excision Repair with Purified Human Proteins (1999)

Among the different base excision repair pathways known, the long patch base excision repair of apurinic/apyrimidinic sites is an important mechanism that requires proliferating cell nuclear antigen. We have reconstituted this pathway using purified human proteins. Our data indicated that efficient repair is dependent on six components including AP endonuclease, replication factor C, proliferating cell nuclear antigen, DNA polymerases delta or epsilon, flap endonuclease 1, and DNA ligase I. Fine mapping of the nucleotide replacement events showed that repair patches extended up to a maximum of 10 nucleotides 3' to the lesion. However, almost 70% of the repair synthesis was confined to 2-4-nucleotide patches and DNA ligase I appeared to be responsible for limiting the repair patch length. Moreover, both proliferating cell nuclear antigen and flap endonuclease 1 are required for the production and ligation of long patch repair intermediates suggesting an important role of this complex in both excision and resynthesis steps.
[Expression of antisecretory factor and aquaporin 1, 2 in the rat inner ear and their interaction]. (2007)

(1) AF, AQP1 and AQP2 have its individual specific localization in the rat inner ear, which was close to the parts of endolymph, so regulating water of the endolymph may be possible. (2) The range of localization of AF overlapped the distribution of AQP1 and AQP2. The results showed the existence of AF protein in the immunoprecipitate using co-immunoprecipitation combined with Western Blot. It suggested that the interaction between AQP1, AQP2 and AF might be possible.
<b>The Structures of Mitomycins A, B and C and Porfiromycin--Part I</b> (1962)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe Structures of Mitomycins A, B and C and Porfiromycin--Part IJohn S. Webb, Donna B. Cosulich, John H. Mowat, James B. Patrick, Robert W. Broschard, Walter E. Meyer, Richard P. Williams, Carl F. Wolf, William. Fulmor, Charles. Pidacks, and John E. LancasterCite this: J. Am. Chem. Soc. 1962, 84, 16, 3185–3187Publication Date (Print):August 1, 1962Publication History Published online1 May 2002Published inissue 1 August 1962https://pubs.acs.org/doi/10.1021/ja00875a032https://doi.org/10.1021/ja00875a032research-articleACS PublicationsRequest reuse permissionsArticle Views398Altmetric-Citations155LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Temperature-induced switch to the pathogenic yeast form of <i>Histoplasma capsulatum</i> requires Ryp1, a conserved transcriptional regulator (2008)

Histoplasma capsulatum, a fungal pathogen of humans, switches from a filamentous spore-forming mold in the soil to a pathogenic budding-yeast form in the human host. This morphologic switch, which is exhibited by H. capsulatum and a group of evolutionarily related fungal pathogens, is regulated by temperature. Using insertional mutagenesis, we identified a gene, RYP1 (required for yeast phase growth), which is required for yeast-form growth at 37 degrees C. ryp1 mutants are constitutively filamentous irrespective of temperature. Ryp1 is a member of a family of fungal proteins that includes Wor1, a master transcriptional regulator of the white-opaque transition required for mating in Candida albicans. Ryp1 associates with its own upstream regulatory region, consistent with a direct role in transcriptional control, and both the protein and its transcript accumulate to high levels in wild-type yeast-phase cells. Microarray analysis demonstrated that Ryp1 is required for the expression of the vast majority of yeast-specific genes, including two genes linked to virulence. Thus, Ryp1 appears to be a critical transcriptional regulator of a temperature-regulated morphologic switch in H. capsulatum.
La construcción de modelos de prohombre en el liberalismo isabelino (2009)

A mutually inclusive model directing the development of critical thinking includes facilitating critical thinking dispositions or affective attributes of individuals as well as their critical thinking skills. This inclusion takes into account personal and subjective ways of making meaning as part of the conceptualization of critical thinking. There is a gap in understanding the disposition dimensions of critical thinking among professional nursing students and how they may relate with other behavioral aspects. Many baccalaureate programs have been found to define and/or measure critical thinking as primarily cognitive in nature. Guided by this crucial omission of knowledge regarding critical thinking dispositions, this study addressed the following research questions: (1) What are the critical thinking dispositions and learning styles of baccalaureate nursing students? and (2) Are there correlations between critical thinking dispositions and learning modes? A descriptive, correlational study was conducted in which the California Critical Thinking Disposition Inventory and Kolb's Learning Style Inventory were administered to two convenience groups of senior-level nursing students (n = 100). Low critical thinking self-confidence mean scores for both groups were found. Other disposition scores that reflected weaknesses were analyticity, systematicity, and inquisitiveness. Strong disposition scores are described as are dominant learning styles. The Spearman Rank-Difference Correlation measurement indicated relationships between specific components of critical thinking dispositions and learning modes. Implications for nursing education are presented.
Calculated electrostatic properties of ion traps (1986)

A trap for charged particles is an important tool in many important experiments in atomic physics. The electrodes in many such traps are truncated hyperboloids. Data given here allow evaluation of the effects on trap performance of some of the details of the truncation. It is shown that if the truncation of the ring and endcap electrodes is done in a ``balanced'' way the performance degradation can be small. Some specific designs are suggested and some appropriate data reported.
Rhythmic Response of <i>Serratia marcescens</i> to Elevated Temperature (1965)

Dimmick, Robert L. (University of California, Berkeley). Rhythmic response of Serratia marcescens to elevated temperature. J. Bacteriol. 89:791-798. 1965.-Populations of Serratia marcescens of varied ages and pretreatments, which had been grown in a chemically defined medium, were subjected to thermal stress at 50 to 56 C. The numbers of survivors were plotted vs. time to form survivor curves, and the curves were assembled to form three-dimensional models. The manner in which survivors varied as a function of age and time of heating was variable and often rhythmic. Different three-dimensional patterns were found when different inoculum for the test culture was used. Apparently some "dead" cells again produced colonies after extended heating periods (recuperation); this tendency varied with the age of the culture. Diminutive colony forms, which produced normal colonies upon transfer, appeared and disappeared during heating; this tendency fluctuated with age. It is suggested that survivor curves represent a distribution of resistant forms within the population, and that this distribution varies in a manner best described in terms of servomechanistic response within each cell and within a given culture. Difficulties of attempting to relate changes in specific molecular species to subsequent whole-cell responses are discussed.
Parallel hierarchical routing for VLSI on a transputer network (1989)

As the problems of design complexity management of VLSI continue to grow, designers have sought methods to reduce the time taken in bringing a system-level design to final silicon. The increasing use of design automation and the exploitation of system hierarchy wherever possible have both been crucial in this context. Due to the computational complexity of the layout process (placement and routing), it takes up a very large part of the time required to design an integrated circuit. Exploiting parallelism is one of the ways of gaining substantial reductions in the time required to perform the layout phase of the VLSI design process, leading to significant reductions in the cost of producing an IC design. The paper describes research into a novel technique for exploiting parallelism in the automatic routing process for hierarchical chip design. A parallel routing model has been set up to be as flexible as possible to that the hardware on which it is based can be used to speed up all phases of the VLSI design cycle. >
Drug Development for Central Nervous System Diseases Using In vitro Blood-brain Barrier Models and Drug Repositioning (2020)

An important goal of biomedical research is to translate basic research findings into practical clinical implementation. Despite the advances in the technology used in drug discovery, the development of drugs for central nervous system diseases remains challenging. The failure rate for new drugs targeting important central nervous system diseases is high compared to most other areas of drug discovery. The main reason for the failure is the poor penetration efficacy across the blood-brain barrier. The blood-brain barrier represents the bottleneck in central nervous system drug development and is the most important factor limiting the future growth of neurotherapeutics. Meanwhile, drug repositioning has been becoming increasingly popular and it seems a promising field in central nervous system drug development. In vitro blood-brain barrier models with high predictability are expected for drug development and drug repositioning. In this review, the recent progress of in vitro BBB models and the drug repositioning for central nervous system diseases will be discussed.
Phosphorylation sites mapping in the N-terminal domain of c-myc modulate its transforming potential. (1993)

The nuclear proto-oncoprotein c-Myc is involved in the regulation of cell growth and differentiation. c-Myc is phosphorylated at multiple sites in vivo, two of which we have identified near the amino terminus. In chicken Thr-61/Ser-65 are phosphorylated, as are the comparable positions, Thr-58/Ser-62 in human c-Myc. These residues are located within a domain that is implicated in transactivation and is important for the transforming potential of the protein. Furthermore, these phosphorylation sites or nearby amino acids are frequently mutated in v-myc and in several c-myc genes from Burkitt's lymphoma cells. In vitro these two phosphorylation sites can be modified by glycogen synthase kinase 3 and mitogen activated protein kinase. To address their biological importance we mutated these amino terminal phosphorylation sites separately and together. Stably transfected Rat1A cells expressing the mutated proteins have an increased growth potential in soft agar compared to wt-c-myc transfectants. These altered transformation characteristics indicate that Myc function may be negatively regulated by the amino terminal phosphorylation.
Biology of anaerobic microorganisms (1989)

Geochemistry and Biogeochemistry of Anaerobic Habitats (A. Zehnder & W. Stumm). Microbiology, Physiology, and Ecology of Phototrophic Bacteria (M. Madigan). Molecular Mechanisms of Bacterial Photosynthesis (J. Amesz & D. Knaff). Ecology of Denitrification and Dissimilatory Nitrate Reduction to Ammonium (J. Tiedje). Dissimilatory Reduction of Oxidized Nitrogen Compounds (A. Stouthamer). Microbial Reduction of Manganese and Iron (W. Ghiorse). Anaerobic Microbial Degradation of Cellulose, Lignin, Oligolignols, and Monoaromatic Lignin Derivatives (P. Colberg). Anaerobic Hydrolosis and Fermentation of Fats and Proteins (M. McInerney). Acetogenesis (J. Dolfing). Microbiology and Ecology of Sulfate- and Sulfur-Reducing Bacteria (F. Widdel). Dissimilatory Reduction of Sulfur Compounds (J. LeGall & G. Fauque). Biogeochemistry of Methanogenic Bacteria (R. Oremland). Biochemistry of Methane Production (G. Vogels, et al.). Principles and Limits of Anaerobic Degradation: Environmental and Technological Aspects (B. Schink). Index.
Technical note: Simple and robust removal of sun glint for mapping shallow‐water benthos (2005)

Specular reflection of solar radiation on non‐flat water surfaces is a serious confounding factor for benthic remote sensing in shallow‐water environments. This problem was recently overcome by Hochberg et al., who provided an effective method for the removal of ‘sun glint’ from remotely sensed images by utilization of the brightness in a near‐infrared (NIR) band. Application of the technique was shown to give an increase in the accuracy of benthic habitat classification. However, as presented, the method is sensitive to outlier pixels, requires a time‐consuming masking of land and cloud, and is not formulated in a manner leading to ease of implementation. We present a revised version of the method, which is more robust, does not require masking and can be implemented very simply. The practical approach described here will hopefully expedite the routine adoption of this effective and simple technique throughout the aquatic remote sensing community.
Application of the zero-crossing rate, LOFAR spectrum and wavelet to the feature extraction of passive sonar signals (2002)

In this paper, the features extraction of passive sonar signals and classification recognition of underwater target are introduced. Due to the complexity and non-stationary of underwater signals, the zero-cross ratio is first used to initially classify the noise signal; then the LOFAR spectrum reflecting non-stationary signal is extracted, and during which the wavelet transform is carried out for some classes of signals. Finally, a fuzzy ART neural network is constructed to carry out the classification. Results of the experiment show that, for six-class target 147 running environments, 5000 realistic data of ship, the mean correct ratio achieves 89%. The result obtained is satisfactory.