gebhart/patrepeval huggingface dataset:
Use of NMR spectrometry for studying the acetolysis of hexamethylenetetramine III. The reaction between hexamethylenetetramine and acetic anhydride to form TRAT (1987)

Abstract The acetolysis of hexamethylenetetramine (HA) to form 1,3,5‐triacetyl‐1,3,5‐triazacyclohexane (TRAT) has studied by NMR. It was found that this reaction experienced two different courses. HA turned to TRAT through the intermediate 3,7‐diacetyl‐1,3,5,7‐tetraaza‐[3.3.1]‐bicyclononace (DAPT), and HA converted at first to an intermediate M 1 , which gave TRAT through another intermediate M 2 in the presence of water. Based on the 1 H and 13 C spectra, the change in the spectra with reaction and the possibility of reaction, we assumed both the structure of M 2 and its reaction mechanism.
Some remarks on the history of fracture mechanics (2009)

This paper is an essay over the evolution of fundamental ideas of fracture mechanics. This evolution is described from an historical point of view following three major directions: experimental methods, numerical methods and analytical methods. It starts from the observation of Leonardo da Vinci from the fifteenth century and goes until the present time, pointing out the most important moments and ideas in the evolution of fracture mechanics.
Acquisition of neuroendocrine characteristics by prostate tumor cells is reversible: implications for prostate cancer progression. (1999)

Neuroendocrine (NE) cells occur as scattered foci within prostatic adenocarcinoma, similar to their distribution within ductal epithelial cells of the normal prostate. However, the density of NE cells is often greater in prostate carcinomas than in normal tissue, and the frequency of NE cells correlates with tumor grade, loss of androgen sensitivity, autocrine/paracrine activity, and poor prognosis. Although NE cells are nonmitotic, proliferating cells are found in direct proximity to them, suggesting that NE cells provide paracrine stimuli for surrounding carcinoma cells. In vitro, differentiation of the LNCaP and PC3M prostatic tumor cell lines to a NE phenotype can be induced by dibutyryl cyclic AMP (cAMP), suggesting that physiological agents that increase intracellular concentrations of cAMP might regulate NE differentiation in vivo. Indeed, we demonstrate in this report that LNCaP cells acquire NE characteristics in response to treatment with physiological and pharmacological agents that elevate intracellular cAMP, agents such as epinephrine, isoproterenol, forskolin, and dibutyryl cAMP. The androgen-independent LNCaP-derived cell line C4-2 also responded to these agents, indicating that cells representing later stages of tumor progression are also capable of differentiation. The NE phenotype in this study was monitored by the appearance of dense core granules in the cytoplasm, the extension of neuron-like processes, loss of mitogenic activity, and expression of the NE markers neuron-specific enolase, parathyroid hormone-related peptide, neurotensin, serotonin, and chromogranin A. However, contrary to previous reports, we observed rapid loss of the NE phenotype in both LNCaP and C4-2 cells upon withdrawal of inducing agents. Withdrawal also resulted in a rapid, dramatic increase in tyrosine kinase and mitogen-activated protein kinase activities, suggesting that activation of these intracellular signaling enzymes may be important for reentry into the cell cycle. Together, these results indicate that chronic cAMP-mediated signaling is required to block proliferation of prostate tumor cells and to induce NE differentiation.
Transvaginal Natural Orifice Transluminal Endoscopic Surgery (Notes): Surgical Technique and Results (2011)

using transvaginal NOTES in humans appeared in the literature. In this chapter we will discuss Natural Orifice Transluminal Endoscopic Surgery with the vagina as the point of entry into the abdominal cavity.
Physiological and Molecular Response of Prorocentrum minimum to Tannic Acid: An Experimental Study to Evaluate the Feasibility of Using Tannic Acid in Controling the Red Tide in a Eutrophic Coastal Water (2016)

Bioassay and gene expression experiments were conducted in order to evaluate the growth and physiology of Prorocentrum minimum isolated from a eutrophic coastal water in response to tannic acid. In the bioassay experiments, variations in abundance, chlorophyll (chl) a concentration, maximum fluorescence (in vivo Fm), and photosynthetic efficiency (Fv/Fm) were measured over the course of a seven-day incubation. Moreover, stress-related gene expression in both the control and an experimental (2.5 ppm TA treatment) group was observed for 24 h and 48 h. The molecular markers used in this study were the heat shock proteins (Hsp70 and Hsp90) and cyclophilin (CYP). The findings show that P. minimum can thrive and grow at low concentrations (<2.5 ppm) of tannic acid, and, above this concentration, cells begin to slow down development. In addition, TA concentration of 10 ppm halted photosynthetic activity. At the molecular level, treatment with tannic acid increased the expression of Hsp70, Hsp90, and CYP, and heat shock proteins are more upregulated than the cyclophilin gene. Exposure to tannic acid increased the expression of stress factors over time (48 h) by 10- to 27-fold the expression level of the control group. These results suggest that tannic acid can be used to control harmful algal blooms such as those containing P. minimum in eutrophic coastal waters.
Acercamiento a un modelo didáctico para la formación de la competencia prescripción del ejercicio físico (2018)

In the work that is presented, which is part a wider work is essential form of support by the authors a didactic model training in the proficiency prescription of physical exercise in the area of biological sciences degree in physics culture, which manifested as a distinguishing feature from other research on the prescription of physical exercise, integration as a whole of interrelated components of the aspects more common to allow identify proficiency prescription of exercise physical.
Optimization of center of gravity algorithms in a Shack-Hartmann sensor (2006)

We propose analytical studies supported by simulation of various centroiding algorithms for Shack-Hartmann based wavefront sensor. We focused on the simple center of gravity as well as one of its optimization, the weighted center of gravity. Noise effects, as well as linearity issues and high flux bias induced by sub-aperture size and PSF structures are investigated. For each method, optimal parameters are defined in function of photon flux, readout noise, and turbulence level.
Análisis modal de fallos y efectos del proceso de prescripción, validación y dispensación de medicamentos (2011)

By applying a failure modes and effects analysis to the prescription, validation and dispensing process, we have been able to identify critical aspects, the stages in which errors may occur and the causes. It has allowed us to analyse the effects on the safety of the process, and establish measures to prevent or reduce them.
Using n-gram analysis to cluster heartbeat signals (2012)

The two experiments presented in this paper demonstrate that AIIA method can categorize different heart diseases. Both experiments acquired the best category results when using the Bayesian Network. For future work, the concept of the AIIA method can be extended to the categorization of other physiological signals. More features can be added to improve the accuracy.
Electroencephalographic Characteristics of Emergence from Propofol/Sufentanil Total Intravenous Anesthesia (1995)

We recorded the electroencephalogram (EEG) in 16 patients during propofol/sufentanil total intravenous anesthesia to determine whether EEG changes might predict imminent awakening during emergence.Changes in absolute and relative power in four frequency bands, median frequency (MF), 95th percentile frequency (F95), and two frequency band power ratios (beta/alpha and (alpha + beta)/delta) were quantified. One minute before eye opening, absolute power in the delta and alpha bands had decreased to 49% (25%-73%) and 42% (25%-58%) of the value during the infusion (P > 0.005). MF, F95, and the two frequency band power ratios increased during emergence (P > 0.05). Of the individual spectral variables, only a 50% decrease in absolute alpha power was more than 90% sensitive and specific in predicting eye opening. We conclude that, although pronounced EEG changes occur during emergence from propofol/sufentanil anesthesia, the EEG does not reliably predict eye opening. (Anesth Analg 1995;81:366-71)
Effects of doping pairs on the preparation and dielectricity of PLZT ceramics (1986)

By doping Li2CO3, Na2CO3, B2O3 and Bi2O3 into PLZT 8/65/35, the diffuse phase transition is enhanced and the sintering temperature is lowered. In order to balance out the charge fluctuations caused by doping, a R-a-R3+b pair doping is adopted. Low temperature coefficient of capacitance (TCC) of the doped PLZT 8/65/35 can be obtained by Na+-B3+ or Li+-Bi3+ pair dopings. The sintering temperature is lowered down to 1050°C or below. The enhancement in diffuse phase transition is explained by the possible interstitial site occupancy of Li+ and Bi3+. Annealing in air at 970°C can effectively drive out the doped ions, and cause the recovery of the lattice structure.
Improved isolation of Escherichia coli O157 using large enrichment volumes for immunomagnetic separation (2000)

The recovery of low numbers of Escherichia coli O157 in foods by immunomagnetic separation (IMS) was improved, on average, ninefold by increasing the enrichment volume tested from 1 to 10 ml while maintaining the volume of immunobeads constant at 0.02 ml. Although 50 ml volumes also gave improved recoveries (approximately threefold), the 50 ml volume cannot be recommended until a suitable magnetic separation apparatus has been developed. By testing 10 ml volumes, the improved sensitivity of the IMS procedure will reduce false-negative E. coli O157 tests and help improve epidemiological studies of this pathogen.
A Text Mining Approach to the Prediction of Disease Status from Clinical Discharge Summaries (2009)

OBJECTIVE The authors present a system developed for the Challenge in Natural Language Processing for Clinical Data-the i2b2 obesity challenge, whose aim was to automatically identify the status of obesity and 15 related co-morbidities in patients using their clinical discharge summaries. The challenge consisted of two tasks, textual and intuitive. The textual task was to identify explicit references to the diseases, whereas the intuitive task focused on the prediction of the disease status when the evidence was not explicitly asserted. DESIGN The authors assembled a set of resources to lexically and semantically profile the diseases and their associated symptoms, treatments, etc. These features were explored in a hybrid text mining approach, which combined dictionary look-up, rule-based, and machine-learning methods. MEASUREMENTS The methods were applied on a set of 507 previously unseen discharge summaries, and the predictions were evaluated against a manually prepared gold standard. The overall ranking of the participating teams was primarily based on the macro-averaged F-measure. RESULTS The implemented method achieved the macro-averaged F-measure of 81% for the textual task (which was the highest achieved in the challenge) and 63% for the intuitive task (ranked 7(th) out of 28 teams-the highest was 66%). The micro-averaged F-measure showed an average accuracy of 97% for textual and 96% for intuitive annotations. CONCLUSIONS The performance achieved was in line with the agreement between human annotators, indicating the potential of text mining for accurate and efficient prediction of disease statuses from clinical discharge summaries.
Posthumanism Invited to Dinner: Exploring the Potential of a More-Than-Human Perspective in Food Studies (2019)

Research Article| May 01 2019 Posthumanism Invited to Dinner: Exploring the Potential of a More-Than-Human Perspective in Food Studies Sarah Elton Sarah Elton University of Toronto Sarah Elton is a PhD candidate at the Dalla Lana School of Public Health at the University of Toronto, where she researches in the area of ecological public health and food sovereignty. Her work is supported by a scholarship from the Social Sciences and Humanities Research Council, and during the writing of her article in this issue she was a graduate fellow at the University of Toronto Scarborough's Culinaria Research Centre. Sarah is also the author of several bestselling books, including Consumed: Food for a Finite Planet (University of Chicago Press, 2013) and Starting from Scratch for young readers. Search for other works by this author on: This Site PubMed Google Scholar Gastronomica (2019) 19 (2): 6–15. https://doi.org/10.1525/gfc.2019.19.2.6 Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn MailTo Tools Icon Tools Get Permissions Cite Icon Cite Search Site Citation Sarah Elton; Posthumanism Invited to Dinner: Exploring the Potential of a More-Than-Human Perspective in Food Studies. Gastronomica 1 May 2019; 19 (2): 6–15. doi: https://doi.org/10.1525/gfc.2019.19.2.6 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentGastronomica Search This content is only available via PDF. © 2019 by the Regents of the University of California. All rights reserved. Please direct all requests for permission to photocopy or reproduce article content through the University of California Press's Reprints and Permissions web page, http://www.ucpress.edu/journals.php?p=reprints.2019 Article PDF first page preview Close Modal You do not currently have access to this content.
Analysis of Characteristics of Type III Drift Pair Bursts (2002)

Six metric type Ⅲ bursts with bidirectional frequency drifts observed with the Acousto-Optic Spectrograph at the Yunnan Observatory during the 22nd solar cycle are analysed in the present article.These events respectively reveal that the demarcation frequencies between the positive and negative drift bursts are in between 244 MHz and 272 MHz. The radiation mechanism of the type Ⅲ drift pair events is also discussed from the observation characteristics.
The Relationship Between Exchange Rates and Stock Prices: A Causality Analysis (2015)

This paper analyzes empirically the relationship between stock prices and exchange rates by using high-frequency data of exchange rates and aggregate stock indices of Turkey. With time-series techniques, this study provides evidence that a long-run stable relationship between stock indices and exchange rate exist. But our results indicate that causality relationship exists only from exchange rate to industry sector index.
Simple perturbation theory estimates of equilibrium constants from force fields (1991)

We propose and test a very simple method for calculating equilibrium constants from quartic force fields.
Changes in Level and Activity of Phospholipid Transfer Protein during Maturation and Germination of Maize Seeds (1989)

The variations of the amounts of phospholipid transfer proteins (PLTP), determined by ELISA and immunoblotting methods, were followed during the maturation and germination of maize (Zea mays L.) seeds. Changes of the amounts of PLTP occur during seed maturation. The levels of PLTP, low in the first 3 weeks after fecondation, strongly raised 3 to 5 weeks after, then reached and maintained a high value (10% of total soluble proteins) during the last steps of maturation. These variations, determined by ELISA, are in accordance with the observations made by immunoblotting. Changes in phospholipid transfer activity were also found when protein extracts prepared from seeds at different stages of maturation were assayed for transfer activity. The levels of PLTP were also determined during the germination of maize seeds and the early growth of the plantlets, both in the endosperm and the aerial parts. While no major change was observed in the endosperm, a high increase in PLTP level was found in the aerial part of the plantlet, both by ELISA and immunoblotting. An enhancement of the phospholipid transfer activity was parallely observed in the protein extracts of plantlets at various stages of germination. These results are consistent with an in vivo correlation between the synthesis of phospholipid transfer protein, observed during the maturation and germination of maize seeds, and the biogenesis of membranes which involves intracellular movements of phospholipids.
Microstructure and recording properties of bicrystal disks with GaAs substrates (1994)

Bicrystal disks with CoCrTa magnetic layer and Cr underlayer were fabricated on {001} GaAs single crystalline wafers. It is found that the epitaxial orientation relationship of Cr onto GaAs is {001}<110> Cr/spl par/{001}<110> GaAs. Disks with coercivity up to 2600 Oe, accompanied by near unity coercive and remanent squarenesses, were obtained. Measured medium noise power is extremely low and remains unchanged as recording density increases up to 4000 fr/mm. The recording properties of the bicrystal media are compared with those of conventional longitudinal thin film media which have similar coercivities.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
37. Fluorescent reagents. Acyl chlorides and acyl hydrazides (1950)

W. Baker, C. N. Haksar and J. F. W. McOmie, J. Chem. Soc., 1950, 170 DOI: 10.1039/JR9500000170
[Ropivacaine--a new local anesthetic with specific properties]. (1990)

Ropivacaine is the (S)-enantiomer of 1-propyl-2',6'-pipecoloxylidide. In terms of its physicochemical properties, it is a long-acting local anesthetic (molecular weight of the base 274, pKa 8.07, protein-binding 92%). It shows a selective action on A delta and C fibers. This may be attributable to its relatively low partition coefficient (6.1 in n-heptane). The subcutaneous and intravenous acute toxicity (LD50) is lower than that of other long-acting local anesthetics. Because of its vasoconstrictor potency, its use as a vasoconstrictor-free solution is of particular interest.
The design of a wireless-controlled intra-oral electrolarynx. (1977)

Many patients who have failed to acquire esophageal speech after total laryngectomy are presently using artificial electrolarynges. Two of the principle objections to currently available devices are their bulkiness and visibility. The authors have developed and tested a wireless-controlled intra-oral electrolarynx which overcomes these main objections. In addition, it produces intelligible speech which compares favorably with other existing devices. In this paper, the design details will be presented which significantly influence the performance and the patients' acceptability of the new device.
Rapid thermal annealing of Cu-In/Se stacked layers (1991)

A rapid thermal annealing technique has been reported to prepare CuInSe2 films from Cu-In/Se stacked layers. A non-aqueous bath has been used to grow the Cu-In alloy films. Steady state polarization characteristics of the alloy plating bath are also discussed. From the XRD and SEM results, it is shown that the CuInSe2 films are polycrystalline and have a preferred (112) orientation of the chalcopyrite phase.
Concurrent preoperative chemotherapy and radiation therapy in localized esophageal adenocarcinoma (1992)

Twenty-four patients with localized, potentially resectable adenocarcinoma of the esophagus were enrolled in this study to evaluate the use of preoperative chemotherapy and radiation therapy, followed by transhiatal esophagectomy. The patients were newly diagnosed and had received no prior treatment. Radiation therapy consisted of 4900 cGy, administered as 350-cGy fractions 5 days a week for 14 fractions. The chemotherapy consisted of 5-fluorouracil 300 mg/m2/day administered as a continuous 24-hour intravenous infusion for 96 hours each week, concomitantly with the radiation therapy. After a 3-week rest, patients underwent transhiatal esophagectomy. Twenty-two patients could be observed for their responses to the chemotherapy and radiation regimen. Radiographically, 41% showed improvement, 36% had stable disease, and 23% had progression. Nineteen patients underwent surgery; all patients had total gross removal of disease, and two patients had a complete histologic response. All 24 patients could be examined for toxicity assessment. There were three deaths during the treatment period: one patient died of a perioperative complication, one of pneumonia, and one of a myocardial infarction. Eleven patients eventually had pleural and/or pericardial effusions, and six of these were symptomatic. All 24 patients could be examined for survival analysis. The median follow-up for all patients was 12.5 months, with 32.5 months for all surviving patients. Median survival was reached at 11 months. Disease-free survival was 9.5 months. It was concluded that the radiation-fractionation schedule in this preoperative regimen was associated with marked toxicity in the form of pleural and pericardial effusions. There was no improvement in survival compared with historic controls. The role of combined preoperative treatment in this patient population has yet to be determined.
Acoustoelastic Theory for Plastically Deformed Solids (1990)

In this paper, we have attempted to precisely formulate a generalized acoustoelastic theory by extending the theory proposed by Kobayashi [1987], which was derived to evaluate acoustoelastic effects of ultrasonic waves induced by slight orthotropy in elasticity and plastic anisotropy growth in plastically deformed solids. Moreover, in order to examine the accuracy of the proposed theory, numerical calculations of the transverse wave velocity changes in the elastoplastic range were carried out and compared with the experimental data on a commercially available pure aluminum specimen subjected to uniaxial tension. The good agreement between theoretical and experimental results indicates that the plastic anisotropy is closely related to the acoustoelastic effects through the elastoplastic coupling strain rate induced by the vertexlike yield effects at the corner of the yield surface.
A tracking-by-detection method with radio-frequency tomography network (2013)

This paper presents a tracking-by-detection method which can localize and track an unknown and time-varying number of moving objects with radio-frequency tomography network. First, a novel detection method based on scanning circles is proposed to preliminarily estimate the number of targets and determine the multi-target positions using the received signal strength measurements. Then, particle probability hypothesis density filter algorithm is applied to perform target tracking and eliminate false positives caused by multipath environment or system noise. Experimental results demonstrate that the tracking-by-detection method achieves high accuracy in estimating target number and positions.
The spider toxin, argiotoxin<sub>636</sub>, binds to a Mg<sup>2+</sup> site on the N‐methyl‐<scp>d</scp>‐aspartate receptor complex (1991)

1. The mechanism of action of the arylalkylamine spider toxin, argiotoxin636, on the N-methyl-D-aspartate (NMDA) receptor was investigated by use of [3H]-dizocilpine binding to well-washed membranes obtained from rat brain. 2. Argiotoxin636 decreased [3H]-dizocilpine binding with an apparent potency of about 3 microM. The inhibition of [3H]-dizocilpine by argiotoxin636 was insensitive to the concentration of glutamate, glycine and spermidine in the assay. 3. Argiotoxin636 alone had no effect on the dissociation of [3H]-dizocilpine. However, argiotoxin636 reversed the actions of Mg2+ on the dissociation of [3H]-dizocilpine by decreasing the apparent potency of Mg2+. Argiotoxin636 also reversed the action of Ca2+ on the dissociation of [3H]-dizocilpine. 4. These results suggest that argiotoxin636 exerts a novel inhibitory effect on the NMDA receptor complex by binding to one of the Mg2+ sites located within the NMDA-operated ion channel.