gebhart/patrepeval huggingface dataset:
XML on LDAP network database (2002)

This paper outlines a design that uses the eXtensible Markup Language (XML) to describe the network database scheme. The XML information is encapsulated in the lightweight directory access protocol (LDAP) messages. The LDAP has already established itself as a popular directory search protocol. Typically, the LDAP response message can carry unintelligible information at the LDAP layer. In the design in this paper, this information is passed to an XML parser and translator for further processing. As a result, we can modify, update database information without taking down the whole system. This is the main objective in combining both XML and LDAP in a network model. We investigate two aspects in this paper. The first objective is to use the flexibility and extensibility of XML that allow us to change the database contents dynamically. The second objective is to demonstrate that the combination of XML and LDAP can be a powerful tool in delivering dynamic database content to different recipients on-the-fly.
Long-term clinical results of chairside Cerec CAD/CAM inlays and onlays: a case series (2008)

The survival rate probability of 88.7% after up to 17 years of clinical service for Cerec computer-aided design/computer-assisted machining restorations made of Vita Mk I feldspathic ceramic is regarded as a very respectable clinical outcome.
Serotonin and fluoxetine modulate bone cell function in vitro (2006)

Recent studies have proposed a role for serotonin and its transporter in regulation of bone cell function. In the present study, we examined the in vitro effects of serotonin and the serotonin transporter inhibitor fluoxetine "Prozac" on osteoblasts and osteoclasts. Human mononuclear cells were differentiated into osteoclasts in the presence of serotonin or fluoxetine. Both compounds affected the total number of differentiated osteoclasts as well as bone resorption in a bell-shaped manner. RT-PCR on the human osteoclasts demonstrated several serotonin receptors, the serotonin transporter, and the rate-limiting enzyme in serotonin synthesis, tryptophan hydroxylase 1 (Tph1). Tph1 expression was also found in murine osteoblasts and osteoclasts, indicating an ability to produce serotonin. In murine pre-osteoclasts (RAW264.7), serotonin as well as fluoxetine affected proliferation and NFkappaB activity in a biphasic manner. Proliferation of human mesenchymal stem cells (MSC) and primary osteoblasts (NHO), and 5-HT2A receptor expression was enhanced by serotonin. Fluoxetine stimulated proliferation of MSC and murine preosteoblasts (MC3T3-E1) in nM concentrations, microM concentrations were inhibitory. The effect of fluoxetine seemed direct, probably through 5-HT2 receptors. Serotonin-induced proliferation of MC3T3-E1 cells was inhibited by the PKC inhibitor (GF109203) and was also markedly reduced when antagonists of the serotonin receptors 5-HT2B/C or 5-HT2A/C were added. Serotonin increased osteoprotegerin (OPG) and decreased receptor activator of NF-kappaB ligand (RANKL) secretion from osteoblasts, suggesting a role in osteoblast-induced inhibition of osteoclast differentiation, whereas fluoxetine had the opposite effect. This study further describes possible mechanisms by which serotonin and the serotonin transporter can affect bone cell function.
CFD Analyses of Heat Sinks for CPU Cooling With Fluent (2005)

In this study, forced cooling of heat sinks mounted on CPUs was investigated. Heat sink effectiveness, effect of turbulence models, effect of radiation heat transfer and different heat sink geometries were numerically analyzed by commercially available computational fluid dynamics softwares Icepak and Fluent. The numerical results were compared with the experimental data and they were in good agreement. Conjugate heat transfer is simulated for all the electronic cards and packages by solving Navier-Stokes equations. Grid independent, well converged and well posed models were run and the results were compared. The best heat sink geometry is selected and it is modified in order to have lower maximum temperature distribution in the heat sink. This paper was also originally published as part of the Proceedings of the ASME 2005 Pacific Rim Technical Conference and Exhibition on Integration and Packaging of MEMS, NEMS, and Electronic Systems.
A Smart, Integrated Battery Analysis and Control System with Wireless Communication (2003)

<div class="htmlview paragraph">Micron Corporation is under contract with U.S. Army Tank-Automotive and Armaments Command (TACOM) to develop the prototype of a smart microprocessor based battery analysis and control system for automotive SLI batteries. The system is an integral part of the battery case. It communicates wireless with the vehicle computer for battery status indication, with the alternator for gas controlled pulsed charging and with maintenance personnel to issue maintenance instructions. The system is designed to maintain the original dimensions of a conventional battery and requires no additional wiring from the battery to the vehicle.</div>
Ajax: A New Approach to Web Applications (2007)

Despite this, Web interaction designers can’t help but feel a little envious of our colleagues who create desktop software. Desktop applications have a richness and responsiveness that has seemed out of reach on the Web. The same simplicity that enabled the Web’s rapid proliferation also creates a gap between the experiences we can provide and the experiences users can get from a desktop application.
Controlled ovarian hyperstimulation and intrauterine insemination for treating male subfertility: a controlled study (1998)

In this randomized crossover trial we investigated whether the use of controlled ovarian hyperstimulation with low-dose human menopausal gonadotrophin in couples with male subfertility leads to a higher probability of conception when intrauterine insemination (IUI) is applied. We also investigated whether the efficacy of IUI in natural or stimulated cycles was related to the severity of male subfertility. Seventy-four couples completed 308 treatment cycles. Thirteen pregnancies occurred after IUI in a natural cycle (pregnancy rate per completed cycle: 8.4%) and 21 after IUI in a stimulated cycle (pregnancy rate per completed cycle: 13.7%). The difference between the two treatment modalities was not statistically significant. The efficacy of IUI in stimulated cycles was related to the severity of the semen defect. In couples with a total motile sperm count < 10 x 10(6), ovarian stimulation did not improve treatment outcome, while it did in couples with a total motile sperm count > or = 10 x 10(6). Compared with the expected chance of conceiving spontaneously without treatment, both natural and stimulated cycles improved the probability of conception. We conclude that, for the group as a whole, ovarian stimulation did not improve the probability of conception. However, in couples with less severe semen defects, ovarian stimulation did improve the probability of conception.
Coronavirus Disease 2019 Treatment: A Review of Early and Emerging Options (2020)

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the cause of coronavirus disease 2019 (COVID-19), has spread across the globe resulting in a pandemic. At the time of this review, COVID-19 has been diagnosed in more than 200 000 patients and associated with over 8000 deaths (Centers for Disease Control and Prevention, World Health Organization). On behalf of the Society of Infectious Diseases Pharmacists, we herein summarize the current evidence as of March 18, 2020 to provide guidance on potential COVID-19 treatment options. It is important to caution readers that new data emerges daily regarding clinical characteristics, treatment options, and outcomes for COVID-19. Optimized supportive care remains the mainstay of therapy, and the clinical efficacy for the subsequent agents is still under investigation. Antimicrobial stewardship programs, including infectious diseases pharmacists and physicians, are at the forefront of COVID-19 emergency preparedness. We encourage all readers to continue to assess clinical data as it emerges and share their experience within our community in a well-controlled, adequately powered fashion.
Human Health Consequences of Antimicrobial Drug--Resistant Salmonella and Other Foodborne Pathogens (2005)

There are several clinical and public health consequences associated with antimicrobial drug resistance in non-Typhi Salmonella species and other foodborne pathogens. If bacteria acquire resistance to clinically important antimicrobial drugs, early empirical treatment may fail, and there will be limitations in the choices of treatment after the establishment of microbial diagnosis. Drug-resistant gastrointestinal pathogens preferentially cause illness in persons receiving antimicrobial drugs for any medical condition. Consequently, emerging resistance in foodborne pathogens may result in increased burdens of illness and outbreaks in settings where patients are treated with antimicrobial drugs. Finally, resistance may be associated with increased virulence, and several epidemiological studies have demonstrated that infections with drug-resistant non-Typhi Salmonella serotypes and Campylobacter species are associated with excess mortality and morbidity. Mitigation of drug resistance in foodborne bacteria is likely to be of benefit for human health.
Clinical Estimational of Gestational Age by Means of Neurologic Examination (1980)

Clinical estimation of gestational age at birth has been applied to 181 newborn infants who were born at Ewha Womans University Hospital from July to September 1979. Authors used neurologic examination based on evalution of passive tone, active tone and primary reflexes in order to estimate the gestational age, 1) Correlation coefficient between gestational age calculated from last menstrual period and clinical estimation of gestational age used in this study was 0.833 and regression formula was Y = 0.741+10.27. 2) There was no stastically significant difference in correlation coefficient between S.G.A, A.G.A., and I.G.A. groups. 3) Neurologic examination is objective and reproducible for estimation of gestational age in newborn infants.
[DNA and protein in the postnatal growth of mouse cardiomyocytes]. (1983)

DNA and protein were measured in the cell on bicolour smears stained with the Feulgen reagent and with Naphtol yellow S. The mean protein quantity and histograms are the same for mononuclear and binuclear myocytes with the same ploidy. The growth rate of these cells is also the same. A discrepancy is revealed between the protein content and the gene dosage in growing myocytes: doubling of ploidy was not followed by a corresponding increase in the amount of protein.
A Comprehensive Sensitivity Analysis Framework for Model Evaluation and Improvement Using a Case Study of the Rangeland Hydrology and Erosion Model (2007)

The complexity of numerical models and the large numbers of input factors result in complex interdependencies of sensitivities to input parameter values, and high risk of having problematic or nonsensical model responses in localized regions of the input parameter space. Sensitivity analysis (SA) is a useful tool for ascertaining model responses to input variables. One popular method is local SA, which calculates the localized model response of output to an input parameter. This article describes a comprehensive SA method to explore the parameter behavior globally by calculating localized sensitivity indices over the entire parameter space. This article further describes how to use this framework to identify model deficiencies and improve model function. The method was applied to the Rangeland Hydrology and Erosion Model (RHEM) using soil erosion response as a case study. The results quantified the localized sensitivity, which varied and was interdependently related to the input parameter values. This article also shows that the localized sensitivity indices, combined with techniques such as correlation analysis and scatter plots, can be used effectively to compare the sensitivity of different inputs, locate sensitive regions in the parameter space, decompose the dependency of the model response on the input parameters, and identify nonlinear and incorrect relationships in the model. The method can be used as an element of the iterative modeling process whereby the model response can be surveyed and problems identified and corrected in order to construct a robust model.
Identification of cell-surface heparin/heparan sulfate-binding proteins of a human uterine epithelial cell line (RL95). (1992)

The interaction of heparin (HP) with the cell-surface components of a human uterine epithelial carcinoma cell line (RL95) was studied. Binding of [3H]HP to cell surfaces was saturable in a dose- and time-dependent manner. HP and certain forms of heparan sulfate (HS) efficiently compete for [3H]HP binding. In contrast, other glycosaminoglycans, such as chondroitin sulfate, keratan sulfate, hyaluronic acid, and dermatan sulfate, do not compete for binding to these sites. Scatchard analysis revealed that [3H]HP bound to these sites with an apparent KD of 0.7-0.9 microM and a binding capacity of 9 x 10(6) sites/cell to attached cells. EDTA-detached cells displayed a similar apparent KD, but an approximately 2-fold increase in binding capacity. Protease digestion of cells on ice markedly reduced [3H]HP binding, indicating that these binding sites were associated with proteins. In contrast, heparinase treatment of cells stimulated binding by approximately 2-fold, indicating that a large fraction of these binding sites were occupied with endogenous ligand. We examined the structural features of HP/HS required for HP/HS binding. O-Sulfation, substitution of amino groups, and, to a lesser extent, the presence of carboxyl groups were important recognition features of HP/HS by cell-surface HP/HS-binding sites. N-Sulfation was not required. Photoaffinity labeling with 125I-sulfosuccinimidyl 2-(p-azidosalicylamido)-ethyl-1, 3-dithiopropionate-HP was used to identify HP/HS-binding proteins on RL95 cell surfaces. Proteins with M(r) values of 14,000-18,500 and 31,000 were photolabeled at the surfaces of attached cells. Photolabeling was blocked by the addition of excess HP, but not chondroitin sulfate. Additional proteins with M(r) values greater than 31,000 were photolabeled specifically on EDTA-detached cells. Moreover, the M(r) 14,000-18,500 and 31,000 proteins were retained on the EDTA-detached cells. These observations indicated that certain cell-surface HP/HS-binding proteins were not exposed when cells were attached to substrata. Proteins of similar M(r) values as the photolabeled components as well as many additional proteins were identified by heparin-agarose chromatographic selection of extracts of cells labeled metabolically with [35S]methionine or vectorially with Na125I at the cell surface. Fragments of cell-surface HP/HS-binding proteins were released from intact RL95 and mouse uterine epithelial cells by mild trypsinization and isolated by heparin-agarose affinity chromatography. Three peptides with M(r) values between 6000 and 14,000 required greater than 0.5 M salt for elution from heparin-agarose, retained HP binding activity in a 125I-HP gel overlay assay, and selectively bound [3H]HP in a solid-phase binding assay.(ABSTRACT TRUNCATED AT 400 WORDS)
Mononuclear phagocytes of blood and bone marrow: comparative roles as viral reservoirs in human immunodeficiency virus type 1 infections. (1989)

We examined human immunodeficiency virus (HIV) production in cultured mononuclear cells from 36 seropositive homosexual males. Production was detected by using an HIV p24 antigen ELISA assay in blood mononuclear cells in 54% of asymptomatic, 71% of acquired immunodeficiency syndrome (AIDS)-related complex, and 100% of AIDS patients. When the peripheral blood mononuclear cells were separated into monocytes and CD4+ T cells, we found that the CD4+ T-cell fraction was preferentially infected in the three clinical stages. The ability to isolate HIV from blood monocyte-derived macrophages was similar in the three stages (24-33%) and required coculture with phytohemagglutinin-stimulated lymphoblasts. Bone marrow and blood mononuclear cells cultured simultaneously yielded virus from both sources in 13 individuals. Again the prime source of virus was the nonadherent bone marrow mononuclear cells, which contained CD4+ T cells, and not the adherent monocyte-enriched fraction. We conclude that blood mononuclear cells yield productive virus more readily as disease progresses and that infection is detected in association with CD4+ T-cell-enriched fractions. In our large sample of patients, monocyte infection was detected in only a small fraction, suggesting that this cell type is neither a primary nor an exclusive reservoir of HIV infection.
The Palladium-Hydrogen System (1982)

This article completes the review of the relationship between equilibrium pressure and composition, which was started in the first part of the paper, before going on to consider some other aspects of the hydrogen-palladium system.
Intravenous glycyrrhizin for the treatment of chronic hepatitis C (1998)

van Rossum, T. G.J.; Vulto, A. G.; Hop, W. C.J.; Brouwer, J. T.; Schalm, S. W. Author Information
Where Only Fools Dare to Tread: An Empirical Study on the Prevalence of Zero-Day Malware (2009)

Zero-day malware is malware that is based on zero-day exploits and/or malware that is otherwise so new that it is not detected by any anti-virus or anti-malware scanners. This paper presents an empirical study that exposed updated Micsosoft Windows XP PCs with updated anti-virus software to a number of unsavoury Internet software repositories. A total of 124 zero-day malware instances were detected in our experiment. Our conclusion is that if a user is sufficiently adventurous (or foolish), no anti-virus protection can prevent a zero-day malware infection.
A very simple method to obtain one additional fully regulated output in zero-current-switched quasiresonant converters (2002)

A novel solution to the problem of obtaining an additional fully regulated output in zero current-switched quasi-resonant power converters (ZCS-QRCs) is presented. The solution consists of connecting low-power PWM (pulse width modulation) topology to the resonant switch and modulating the duty cycle (in addition to the switching frequency) in the power transistor. The PWM topology must have a transformer or a tapped-inductor to overcome a constraint between the output voltage gain in both outputs. The converter obtained has a nonzero-current-switching, but the increase in switching losses is very small if the power handled by the new output is much smaller than the one delivered by the main output.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
The Nicotinic Acetylcholine Receptor as a Target for Antidepressant Drug Development (2012)

An important new area of antidepressant drug development involves targeting the nicotinic acetylcholine receptor (nAChR). This receptor, which is distributed widely in regions of the brain associated with depression, is also implicated in other important processes that are relevant to depression, such as stress and inflammation. The two classes of drugs that target nAChRs can be broadly divided into mecamylamine- and cytisine-based compounds. These drugs probably exert their effects via antagonism at α4β2 nAChRs, and strong preclinical data support the antidepressant efficacy of both classes when used in conjunction with other primary antidepressants (e.g., monoamine reuptake inhibitors). Although clinical data remain limited, preliminary results in this area constitute a compelling argument for further evaluation of the nAChR as a target for future antidepressant drug development.
Iodometric Determination of Resorcinol (1950)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTIodometric Determination of ResorcinolH. H. Willard and A. L. WootenCite this: Anal. Chem. 1950, 22, 4, 585–586Publication Date (Print):April 1, 1950Publication History Published online1 May 2002Published inissue 1 April 1950https://pubs.acs.org/doi/10.1021/ac60040a025https://doi.org/10.1021/ac60040a025research-articleACS PublicationsRequest reuse permissionsArticle Views111Altmetric-Citations4LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
The Theory of Halftone Screen Image Formation and its Bearing on Practical Applications (1959)

Practical halftone photography developed at first almost independently of theoretical considerations, although theory based on geometric optics provided some guide for the practical operator. The “diffraction” theory is reviewed; it now provides a fairly complete explanation of halftone image formation, and has further defined the conditions for practical work.The techniques required to produce screen negatives and positives with optimum tonal gradation and dot formation for relief and surface printing are discussed. Some techniques have been made possible by the introduction of new types of photographic emulsion.The development of the “contact” screen is outlined, and the results obtained with available contact and cross-line screens are compared with special reference to the gradation and resolution of the final image.
DENTIFRICES AND MOUTHWASHES INGREDIENTS AND THEIR USE (2003)

Most people brush their teeth twice daily with a toothpaste and many of us even supply this with a mouthwash. Toothpastes and mouthrinses are sold world wide in foodstores, drugstores, chemists, healthstores and some are even sold in dental clinics.\nThe variety of different dentifrices is enormous. Brand names like Colgate, Sensodyne and Solidox are familiar to most of us, but what about brand names such as Bioforce and Ayurdent...? What is it that makes the consumer choose what product he or she wants? Do they wonder about the ingredients added in dentifrices? Do they ask their dental hygienist or dentist for recommendations in order to choose the “right” product? Or is it the grand marketing campaigns from the producers that has the biggest influence?