gebhart/patrepeval huggingface dataset:
Antimicrobial activity of essential oils and chloroform alone and combinated with cetrimide against<i>Enterococcus faecalis</i>biofilm (2013)

The Enterococcus faecalis bacteria have been identified as the most commonly recovered species from teeth with persistent endodontic infections. The antimicrobial activity of essential oils and chloroform (CHL), alone and in association with various concentrations of cetrimide (CTR), against biofilm of Enterococcus faecalis was investigated. Solutions of CHL, eucalyptus oil (EO) and orange oil (OO) associated with CTR at 0.3%, 0.2%, 0.1%, and 0.05% were used to determine antimicrobial activity by exposing treated bovine dentine blocks to E. faecalis. Biofilms grown in the dentine blocks for 7 days were exposed to solutions for 2 and 5 min. Biofilm reduction between OO and EO at 2 min did not show any significant differences; however, OO had a higher kill percentage of biofilms than did the eucalyptus oil at 5 min (p < 0.01). Combinations with CTR at all concentrations achieved a 100% kill rate at 2 and 5 min. The association of CTR with solvent agents achieved the maximum antimicrobial activity against E. faecalis biofilms in dentine.
Ligand Symmetry Modulation for Designing Mixed-Ligand Metal–Organic Frameworks: Gas Sorption and Luminescence Sensing Properties (2016)

Herein, we report the synthesis of a new mixed-linker Zn(II)-based metal-organic framework (MOF), {[Zn2(atz)2(bpydb)](DMA)8}n (1) (atz = deprotonated 3-amino-1,2,4-triazole, bpydb = deprotonated 4,4'-(4,4'-bipyridine-2,6-diyl) dibenzoic acid, DMA = N,N-dimethylacetamide), through symmetry modulation of a triazole ligand. The desymmetrized triazole linkers not only bond to the Zn(II) ions to result in a new helical Zn-triazolate chain building unit but also lead to the formation of a highly porous framework (N2 uptake: 617 cm(3)/g; BET surface area: 2393 m(2)/g) with 1D helical channels. The adsorption properties of desolved 1 were investigated by H2, C2H2, CO2, and CH4 sorption experiments, which showed that 1 exhibited high uptake capacity for H2 at 77 K and C2H2 around room temperature. More importantly, the high C2H2 uptake capacity but low binding energy makes this MOF a promising candidate for effective C2H2 capture from C2H2/CO2 and C2H2/CH4 mixed gases with low regenerative energy cost. In addition, 1 shows potential application for the luminescence sensing of small aromatic molecules picric acid (PA) and p-xylene (PX).
5-Hydroxytryptamine (1958)

Journal Article 5-Hydroxytryptamine Get access 5-Hydroxytryptamine . Edited by Lewis G. P. . 252 pgs., illus. Pergamon Press , New York . ( 1958 ) $9.50 Parkhurst A. Shore Parkhurst A. Shore National Institutes of Health Search for other works by this author on: Oxford Academic Google Scholar AIBS Bulletin, Volume 8, Issue 5, November 1958, Page 45, https://doi.org/10.2307/1292588 Published: 01 November 1958
Optimal management of ankle syndesmosis injuries (2014)

Syndesmosis injuries occur when there is a disruption of the distal attachment of the tibia and fibula. These injuries occur commonly (up to 18% of ankle sprains), and the incidence increases in the setting of athletic activity. Recognition of these injuries is key to preventing long-term morbidity. Diagnosis and treatment of these injuries requires a thorough understanding of the normal anatomy and the role it plays in the stability of the ankle. A complete history and physical examination is of paramount importance. Patients usually experience an external rotation mechanism of injury. Key physical exam features include detailed documentation about areas of focal tenderness (syndesmosis and deltoid) and provocative maneuvers such as the external rotation stress test. Imaging workup in all cases should consist of radiographs with the physiologic stress of weight bearing. If these images are inconclusive, then further imaging with external rotation stress testing or magnetic resonance imaging are warranted. Nonoperative treatment is appropriate for stable injuries. Unstable injuries should be treated operatively. This consists of stabilizing the syndesmosis with either trans-syndesmotic screw or tightrope fixation. In the setting of a concomitant Weber B or C fracture, the fibula is anatomically reduced and stabilized with a standard plate and screw construct. Proximal fibular fractures, as seen in the Maisonneuve fracture pattern, are not repaired operatively. Recent interest is moving toward repair of the deltoid ligament, which may provide increased stability, especially in rehabilitation protocols that involve early weight bearing. Rehabilitation is focused on allowing patients to return to their pre-injury activities as quickly and safely as possible. Protocols initially focus on controlling swelling and recovery from surgery. The protocols then progress to restoration of motion, early protected weight bearing, restoration of strength, and eventually a functional progression back to desired activities.
<title>Fourier optoelectronic signal pre-processor</title> (1994)

This paper describes an attempt to provide a practical application of a fourier optical signal processing as a preprocessor to a digital signal system. The input illumination is a coherent light source from a HeNe laser and computation of the Fourier Transform (FT) is carried out via an FT lens. An object with its symmetry is placed in the front focal plane of the FT lens and at the back focal plane of the lens, the Joint Fourier transform image results. Limitation and boundary condition of the optical system were studied and experimented. Problem encountered during transformation due to differing light source and intensity to various degree of coherency were also considered both at the optical processing and the digital system processor/compensator. Phase measurement and the digital processor/compensator uses the sum-of-product carry save add-subtract unit with reconfigurability so as to allow optimum cost-performance relationship. The sum-of-product consists of 24-bit floating point units capable of performing efficient multiplication, addition and subtraction. Many of such floating-point units are used in parallel in a pipelined architecture to perform Discrete Fourier Transform or other complex function for Digital Signal Processing computations. This also helps to understand the limitation and accuracy of the transformation and the practical behavior of the optical lens-camera system.© (1994) COPYRIGHT SPIE--The International Society for Optical Engineering. Downloading of the abstract is permitted for personal use only.
Modelling of liquid flow after a hydraulic jump on a rotating disk prior to centrifugal atomization (2000)

This paper describes a simplified numerical model which is used to calculate the height distribution, and the radial and tangential velocities of a liquid on a rotating disk after a hydraulic jump and prior to centrifugal atomization. The results obtained from this numerical model are compared with predictions made using previously derived `hydraulic jump' and `analytical' models. Calculations, in conjunction with experimental measurements relating to the trajectory of liquid flow on the atomizing disk, have shown that the numerical model can not only give a reasonable prediction of the hydraulic jump location, but also yields more accurate information regarding the variations in liquid height, and radial and tangential velocities. The model is ideally suited for engineering applications.
Efficient Resource Provisioning Using Virtualization Technology in Cloud Environment (2014)

Cloud computing is the practice of using a network of remote servers hosted on the Internet to store, manage, and process data, rather than a local server or a personal computer. Resource Allocation is the process of assigning available resources to the needed cloud applications over the internet. In computing environment, virtualization means creating a virtual version of a device or a resource, such as server, storage device, network or even an operating system in which the framework divides the resource into one or more execution environments. In this project, we present a system uses virtualization technology to allocate data center resources dynamically based on application demands and support green computing by optimizing the number of servers in use. After the resources are allocated in virtual machines, the measure of skewness is used to identify the unevenness in the multidimensional resource utilization of a server. To minimize skewness, different types of workloads are combined to improve the overall utilization of server resources. This will provide an efficient method for allocating resources in Cloud environment.
Lack of allele-specific efficacy of a bivalent AMA1 malaria vaccine (2010)

This Phase 2 trial of a bivalent AMA1 malaria vaccine found no evidence of vaccine selection or strain-specific efficacy, suggesting that the extreme genetic diversity of AMA1 did not account for failure of the vaccine to provide protection.
Anti-inflammatory effects of essential oil in Echinacea purpurea L. (2013)

Echinacea purpurea L. is a medicinal plant originally from North America. It has become a commonly used herbal medicine worldwide because it contains various biologically active compounds. This study was designed to investigate the anti-inflammatory effects of essential oils from E. purpurea in both mice and rats. The extract was obtained from flower of E. purpurea by steam distillation. The anti-inflammatory potential was evaluated in vivo by using different animal models such as xylene-induced mouse ear edema, egg-white-induced rat paw edema, and cotton-induced granuloma tissue proliferating inflammation in mice. The serial dosages were used in vivo: the low dosage, the medium dosage and the high dosage. The low, medium and high dosages of extracts produced inhibitions of 39.24%, 47.22% and 44.79% respectively in the ear edema induced by xylene when compare with the control group. Only the high dosage group showed statistically significant inhibition (48.51%) of paw edema formation induced three hours by egg white compared with the control group (P<0.01). Moreover, the granulation formation was also significantly reduced the most by 28.52% in the high dose groups compared with the control group (P <0.05). The pro-inflammatory cytokines such as IL-2, IL-6 and TNF-α in the blood were reduced in the treated groups. The essential oils from extracts of E. purpurea have anti-inflammatory effects.
Connecting interface for modularization of digital microfluidics (2008)

Here, interconnection technique to link digital microfluidic chips is proposed. Three kinds of digital microfluidic modules with connecting interface, including flexible module and two types of connector modules, are designed and fabricated. Since these modules are fabricated on a compliant polymer-based substrate (ITO PET), chip-to-chip droplet transportation even at different planes can be achieved by the proposed technique. A low-temperature fabrication process is developed for the polymer substrates, where the SU-8 acts as the insulator. Droplet transportation through electrowetting on curved surface is confirmed by testing on the bended flexible modules with different curvatures from 0 to 0.06 mm<sup>-1 </sup>at around 70 V<sub>AC</sub>. Then the droplet transportations between flexible and connector modules are investigated. It is found that the gap size between two modules and the sidewall profiles at interface affect the droplet transportation directly. For the gap size around 50μm with a smooth perpendicular sidewall profile, 80 V<sub>AC</sub> is shown to actuate droplet of 1.5 μl, 2.5 μl, or 3.5 μl to cross over the interface successfully.
Die polarographische Bestimmung von Tocopherolen und Tocopherylchinonen in Ölen und Fetten (1967)

Abstract Eine Methode zur polarographischen Bestimmung von α‐, γ‐ und δ‐Tocopherol und der entsprechenden Tocopherylchinone in Ölen und Fetten wurde ausgearbeitet. Nach Verseifung der Proben und Extraktion des Unverseifbaren mit Äther werden die im Öl bzw. Fett ursprünglich vorhandenen Tocopherylchinone direkt polarographisch bestimmt. Die in der Probe enthaltenen Tocopherole werden mit Cer(IV)‐sulfat quantitativ zu den entsprechenden Tocopherylchinonen oxydiert und diese dann ebenfalls polarographiert. Im Unverseifbaren neben den Tocopherolen vorliegende Begleitsubstanzen stören die Bestimmung der Tocopherole und Tocopherylchinone nicht. Die Tocopherol‐Gehalte verschiedener Öle und Fette werden mitgeteilt.
Diurnal variation of corneal sensitivity. (1972)

The continuous wear of contact lenses affects corneal sensitivity. A reduction of corneal sensitivity to touch takes place and seems to become greater with the number of hours of wear, becoming significant after 6 to 8 hours of wear. This phenomenon has been demonstrated by several authors and was reviewed by Millodot (I97I). The measurements are carried out before inserting the lens and just after removal. However it is not known how the sensitivity of the cornea would vary throughout the day if the patient were not wearing contact lenses, and the present study was designed to determine the diurnal variation of corneal sensitivity in persons who do not wear contact lenses. Such data provide the control experiment against which the reduction of corneal sensitivity in contact lens wearers must be compared. It will be shown that corneal sensitivity does not diminish throughout the day in the control eyes and that, therefore, the contact lenses must account for the reduction. Moreover, the normal eye actually becomes more sensitive by the evening, so that the reduction brought about by wearing contact lenses is even greater than it appears to be when the sensitivity is measured in the same eye before and after wearing the lens.
Cholomyzon Palpiferum N. Gen., N. Sp., a Siphonostome Cyclopoid Copepod Parasitic in the Coral Dendrophyllia From Madagascar (1969)

Description d'un nouveau genre, Cholomyzon, et d'une nouvelle espece, C. palpiferum, de Copepodes siphonostomes, endoparasite d'un corail malgache, Dendrophyllia. Quoique ce parasite ressemble, par certaines reductions (quasi-absence de P4 et de P5, fusion des articles distaux de l'A1♀) a la famille des Artotrogidae, la structure des appendices cephaliques (A2, mandibule) montre une affinite tres nette avec les Asterocheridae. A l'interieur de cette famille, il se place dans la sous-famille des Cletopontiinae.
Tire-road friction estimation for enhancing the autonomy of wheel-driven vehicles (2007)

For improving the stability of vehicles, especially for autonomous driving, various techniques including vehicle dynamic control, traction control, and anti-lock braking system have been developed and are being adopted. To accomplish these systems, the most important factor is to acquire the tire-road friction characteristics. The majority of tire-road friction estimation algorithms are based on the tire slip ratio and the tracking force obtained by a tire model. However, as the slip ratio and tracking force by a tire model cannot be measured directly and be defined strictly, additional estimation algorithm to get these values are required. Therefore, in this paper, in the view of traditional friction definition, we propose a tire-road friction estimation method that uses the traditional friction model. The real car experimental result shows good performance of the proposed methodology.
Pattern Generation for Complex Data Using Hybrid Mining (2013)

Combined mining is a hybrid mining approach for mining informative patterns from single or multiple data-sources, multiple-features extraction and applying multiple-methods as per the requirements. Data mining applications often involve complex data like multiple heterogeneous data sources, different user preference and create decision-making actions. The complete useful information may not be obtained by using single data mining method in the form of informative patterns as that would consume more time and space. This paper implements hybrid or combined mining approach that applies Lossy-counting algorithm on each data-source to get the frequent data item-sets and then generates the combined association rules. Applying multi-feature approach, we generate incremental pair patterns and incremental cluster patterns. In multi-method combined mining approach, FP-growth and Bayesian Belief Network are combined to generate classifier to get more informative knowledge. This paper uses two different data-sets to get more useful knowledge and compare the results.
Clinical significance of the laboratory determination of low serum copper in adults (2007)

Copper deficiency, Wilson disease (or a carrier state), and aceruloplasminemia are all associated with low serum copper. The presence of coexisting neurological or hematological manifestations that are recognized sequelae of copper deficiency should be considered prior to making a diagnosis of copper deficiency. Gastrointestinal disease or surgery is a common cause of acquired copper deficiency. Even in patients in whom low serum copper is indicative of copper deficiency, the cause of the copper-deficient state may not be evident.
Über Pyromellitsäure‐ und Cumidinsäure‐Derivate. VII. Teil (1962)

Abstract The condensation of dianilino‐pyromellitic acid‐dianhydride (I) and dichloro‐pyromellitic acid‐dianhydride (XI) with substituted anilines gave new derivates of dianilino‐pyromellitic acid‐di‐phenylimide (II).
Maternal Recognition of Pregnancy in the Goat: Effects of Conceptus Removal on lnterestrus Intervals and Characterization of Conceptus Protein Production during Early Pregnancy1 (1989)

Goat conceptuses were surgically removed from the uterus at different days during early pregnancy and cultured for 24-30 h in the presence of L-[3H]leucine to determine the effects of embryo removal on the interestrus interval and to characterize in vitro synthesis and release of conceptus proteins. Normal cyclic and animals (controls) exhibited interestrus intervals of 20.44 +/- 0.89 days. Removal of conceptuses on Days 13 and 15 did not alter interestrus intervals compared to cyclic animals. Removal of conceptuses on Day 17 and times thereafter resulted in significant (p less than 0.05) prolongation of interestrus intervals. These results demonstrate that maternal recognition of pregnancy in the goat occurs between Days 15 and 17. Proteins synthesized and released into the medium by conceptuses were first detectable at Day 16 by the analytical method employed (two-dimensional polyacrylamide gel electrophoresis followed by fluorography). The major protein synthesized at this time was acidic (pI = 5.2-5.7) and consisted of two isotypes with molecular weights of about 17,000. Although patterns of protein production became more complex with conceptus development, this protein remained as a major product through Day 21 but not afterwards. This protein, as well as two other low molecular weight acidic proteins (Mr approximately equal to 21,000, 23,000; pI = 5.7-6.0) were shown by immunoprecipitation to react with anti-ovine trophoblast protein-1 (oTP-1) serum. Hence, these products may comprise a caprine trophoblast protein-1 (cTP-1) complex.(ABSTRACT TRUNCATED AT 250 WORDS)
How AI technology can tame the scientific literature (2018)

As artificially intelligent tools for literature and data exploration evolve, developers seek to automate how hypotheses are generated and validated. As artificially intelligent tools for literature and data exploration evolve, developers seek to automate how hypotheses are generated and validated.
Prediction of Biological Activity Spectra for Substances: Evaluation on the Diverse Sets of Drug-Like Structures (2003)

The concept of Biological Activity Spectrum served as a basis for developing PASS (Prediction of Activity Spectra for Substances) software product. PASS predicts simultaneously more than 780 pharmacological effects and biochemical mechanisms based on the structural formula of a substance. It may be used for finding new targets (mechanisms) for known pharmaceuticals and for searching new biologically active substances. PASS prediction ability was evaluated by activity spectra prediction for 63 substances that are presented in the Molecule of the Month section of Prous Science (http://www.prous.com), belong to different chemical classes and reveal various types of biological activity. Mean accuracy of prediction turned out to be about 90%; therefore, it is reasonable to use PASS for finding and optimizing new lead compounds. A web-site with a new internet version of PASS is introduced into practice in December 2001 (http://www.ibmh.msk.su/PASS). On the site, one can find a detailed description of the PASS approach as well as some examples of its applications, and estimate the quality of prediction by submitting structures of substances with known activities.
Differential effects of early hemisphere damage on lexical comprehension and production (1993)

Abstract The effects of early hemisphere damage on lexical development were investigated in 33 children with unilateral left (n = 21) or right (n = 12) hemisphere damage and 16 normal healthy controls. Single-word naming was assessed using the Expressive One-Word Picture Vocabulary Test (EOW) and lexical comprehension was assessed using the Peabody Picture Vocabulary Test-Revised (PPVT-R). Left lesion subjects (LL) performed comparable to controls in naming, but scored lower than controls on the PPVT-R. Right lesion subjects (RL) scored lower than controls and LL subjects on both the EOW and the PPVT-R. The unexpected superiority of LL in comparison to RL children on the EOW and the PPVT-R argues against a simple left hemisphere dominance for early lexical development. RL subjects' significant comprehension deficits failed to correlate with more general measures of verbal intelligence, supporting a specialized role of the right hemisphere in mediating the acquisition of word meaning.
Related umbilical cord blood transplantation in patients with thalassemia and sickle cell disease (2002)

Allogeneic bone marrow transplantation (BMT) from HLA-identical siblings is an accepted treatment for both thalassemia and sickle cell disease (SCD). However, it is associated with decided risk of both transplant-related mortality (TRM) and chronic graft-versus-host disease (GVHD). We analyzed 44 patients (median age, 5 years; range, 1-20 years) given an allogeneic related cord blood transplant for either thalassemia (n = 33) or SCD (n = 11). Thirty children were given cyclosporin A (CsA) alone as GVHD prophylaxis, 10 received CsA and methotrexate (MTX), and 4 patients received other combinations of immunosuppressive drugs. The median number of nucleated cells infused was 4.0 x 10(7)/kg (range, 1.2-10 x 10(7)/kg). No patient died and 36 of 44 children remain free of disease, with a median follow-up of 24 months (range, 4-76 months). Only one patient with SCD did not have sustained donor engraftment as compared with 7 of the 33 patients with thalassemia. Three of these 8 patients had sustained donor engraftment after BMT from the same donor. Four patients experienced grade 2 acute GVHD; only 2 of the 36 patients at risk developed limited chronic GVHD. The 2-year probability of event-free survival is 79% and 90% for patients with thalassemia and SCD, respectively. Use of MTX for GVHD prophylaxis was associated with a greater risk of treatment failure. Related CBT for hemoglobinopathies offers a good probability of success and is associated with a low risk of GVHD. Optimization of transplantation strategies could further improve these results.