gebhart/patrepeval huggingface dataset:
Vacuum ultra-violet absorption spectra of various mono-substituted benzenes (1965)

The vacuum ultra-violet spectra of various mono-substituted benzenes were measured in the wavelength region of 1550 Å to 2200 Å in the vapour phase by a recording vacuum ultra-violet spectrophotometer. The compounds studied here are phenols (phenol, anisole, phenetole and thiophenol), halogenobenzenes (fluorobenzene, chlorobenzene, bromobenzene and iodobenzene), and toluene. It was found that four π→π* transition bands appear in the wavelength region of 1550 Å to 3000 Å for phenol, anisole, phenetole, fluorobenzene, chlorobenzene and bromobenzene. On the other hand, six π→π* transition bands were found in the same wavelength region for thiophenol and iodobenzene. The absorption spectra of the former group are similar to that of benzene itself. On the other hand, the absorption spectra of the latter group are very different from that of benzene and rather similar to those of the anilines studied in a previous paper. From this point of view, the former group may be regarded as the molecules with weak substituents, and the latter as the molecules with substituents. Theoretical studies of π-electron structures have been carried out with the phenols and halogenobenzenes by considering configurational interactions among the ground, locally excited, and intramolecular charge-transfer configurations. Good agreement was obtained between the experimental and theoretical values for both transition energies and oscillator strengths. It was concluded that the energies of charge-transfer configurations have a great effect upon the absorption spectra of the mono-substituted benzene molecules. That is to say, the charge-transfer configurations lie intermediate between the locally excited configurations for the molecules with strong substituents, while for the molecules with weak substituents they have higher energies than the locally excited configurations. Intramolecular charge-transfer bands were observed for the molecules with strong substituents. The electron affinity of benzene was determined to be -1·1 ± 0·3 eV from the energy of the charge-transfer configuration estimated in such a way as to explain as well as possible the observed absorption spectra of the mono-substituted benzenes under consideration.
Thermoelectric properties of thin film of Graphene-Mesoporous Semiconductor Nanocomposites (2019)

International audience
Effectiveness of Spinal Release and Halo-Femoral Traction in the Management of Severe Spinal Deformity (2004)

The purpose of this retrospective review was to assess the effectiveness of spinal release and halo-femoral traction in the management of severe spinal deformity. Twenty-four patients had halo-femoral traction and a spinal release. Analysis focused on pre-traction curve, preoperative curve in bending or hyperextension films, final traction curve, traction weight as a percent of body weight, and complications associated with traction. The average pre-traction curve was 95 degrees and the average pre-traction curve in bending was 73 degrees; the final traction average curve was 44 degrees. The difference between the magnitude of curve correction in bending and traction films was statistically significant. Traction weight was increased to an average of 54% of body weight. The only complication was a bilateral lower extremity sensory deficit that resolved after traction weight reduction. The average final correction was 71%. Spinal release and halo-femoral traction offer a safe approach to the correction of severe spinal deformities before fusion.
Observation of Zn II, Zn III and Other Unknown Spectral Lines of Zn* (Part 1) (1969)

A number of 176 unknown spectral lines of Zn in the wave-length region from 3400 A to 5200 A have been observed and 90 lines among which have been identified to be of the new lines of Zn III and Zn II as found by Dick K. A. and Crooker A.M. in last year.
CONTINUOUS INTRATHECAL BACLOFEN IN SPINAL CORD SPASTICITY (1992)

Continuous intrathecal infusion of the well known antispastic medication baclofen was evaluated in ten consecutive patients. One year after pump implantation the average Ashworth scale for muscle tone decreased, compared with before treatment, 2.32 points (P < 0.0001), reflexes decreased 2.22 points (P < 0.0001) and the spasm score decreased 1.65 points (P < 0.0001). The average dose increased from 92.22 to 290.95 micrograms (P < 0.0001) between the 1st month of treatment and 1 yr of treatment. The dosage for all patients more than doubled (P < 0.0022) between 3 months and 1 yr postimplantation. There was no significant difference for muscle tone, reflexes or spasms at 3 months v 1 yr. Complications were not unusual and included temporary atelectasis, orthostatic hypotension with escalation of baclofen dose, loss of penile erections, postsurgical pseudo-meningoceles, catheter disruptions and exhausted pump reservoirs. One patient suffered a seizure apparently related to a rapid withdrawal from intrathecal baclofen as a result of catheter sequestration. All patients required a period of intensive inpatient rehabilitation to benefit functionally from the decreased motor tone and/or increased voluntary motor control. The procedure is expensive and close follow-up is necessary for assessing efficacy and refilling the pump. Intrathecal baclofen infusion by subcutaneous pump is useful in treating the effects of spinal spasticity resistant to oral medications. However, there appears to be accommodation to intrathecal baclofen necessitating escalating doses to maintain clinical effects.
The Gene Responsible for Tunicamycin Resistance,<i>tmr B</i>, in<i>Bacillus subtilis</i> (1988)

Journal Article The Gene Responsible for Tunicamycin Resistance, tmr B, in Bacillus subtilis Get access Shigeyoshi Harada, Shigeyoshi Harada Department of Agricultural Chemistry, University of Tokyo, Yayoi, Bunkyo-ku, Tokyo 113, Japan Search for other works by this author on: Oxford Academic Google Scholar Koji Yoda, Koji Yoda Department of Agricultural Chemistry, University of Tokyo, Yayoi, Bunkyo-ku, Tokyo 113, Japan Search for other works by this author on: Oxford Academic Google Scholar Masaki Mori, Masaki Mori Department of Agricultural Chemistry, University of Tokyo, Yayoi, Bunkyo-ku, Tokyo 113, Japan Search for other works by this author on: Oxford Academic Google Scholar Akihiko Tanimoto, Akihiko Tanimoto Department of Agricultural Chemistry, University of Tokyo, Yayoi, Bunkyo-ku, Tokyo 113, Japan Search for other works by this author on: Oxford Academic Google Scholar Takashi Furusato, Takashi Furusato Institute of Biological Sciences, University of Tsukuba, Tsukuba, Ibaraki 305, Japan Search for other works by this author on: Oxford Academic Google Scholar Kunio Yamane, Kunio Yamane Institute of Biological Sciences, University of Tsukuba, Tsukuba, Ibaraki 305, Japan Search for other works by this author on: Oxford Academic Google Scholar Akira Takatsuki, Akira Takatsuki Department of Agricultural Chemistry, University of Tokyo, Yayoi, Bunkyo-ku, Tokyo 113, Japan Search for other works by this author on: Oxford Academic Google Scholar Makari Yamasaki, Makari Yamasaki Department of Agricultural Chemistry, University of Tokyo, Yayoi, Bunkyo-ku, Tokyo 113, Japan Search for other works by this author on: Oxford Academic Google Scholar Gakuzo Tamura Gakuzo Tamura Department of Agricultural Chemistry, University of Tokyo, Yayoi, Bunkyo-ku, Tokyo 113, Japan Search for other works by this author on: Oxford Academic Google Scholar Agricultural and Biological Chemistry, Volume 52, Issue 7, 1 July 1988, Pages 1785–1789, https://doi.org/10.1080/00021369.1988.10868940 Published: 01 July 1988 Article history Received: 05 February 1988 Published: 01 July 1988
Near‐infrared Raman imaging microscope based on fiber‐bundle image compression (1999)

The design and performance of a near-infrared Raman imaging microscope (NIRIM) is described. This new instrument utilizes fiber-bundle image compression (FIC) to collect simultaneously a 3-D Raman spectral imaging data cube. Key NIRIM design features are discussed, including the FIC fiber-bundle, excitation laser, optical coupling to the microscope and fiber-bundle, holographic filtering, spectrograph imaging requirements, CCD parameters and chemical image processing. The theoretical collection efficiency and image quality of the NIRIM instrument are compared with those of tunable filter and line scanning Raman imaging methods. The performance of the NIRIM is demonstrated using a white light image of a bar-target and Raman chemical images of samples containing fructose–sucrose and Pb(NO3)2–K2SO4 microcrystalline mixtures. A Raman image collection time as fast as 1 s (total detector integration time) is demonstrated, for a 3-D data cube containing 322 image resolution elements and 900 Raman shift wavelengths. Copyright © 1999 John Wiley & Sons, Ltd.
ChemInform Abstract: Increasing Rates of Reaction: Microwave‐Assisted Organic Synthesis for Combinatorial Chemistry (2002)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
In utero transplantation: hepatic potential of human CD34+CD45+ progenitors (2004)

Comment on Almeida-Porada et al, page [2582][1] 

In utero–injected, long-term repopulating human hematopoietic stem and progenitor cells are capable of hepatic differentiation in the liver of preimmune sheep. 

Liver-specific injuries applied in rodent models have demonstrated that hematopoietic
Multiscale electrochemistry of hydrogels embedding conductive nanotubes (2015)

The local functionalities of biocompatible objects can be characterized under conditions similar to the operating ones, using scanning electrochemical microscopy (SECM). In the case of alginate beads entrapping carbon nanotubes (CNTs), SECM allows evidencing of the local conductivity, organization, and communication between the CNTs. It shows that the CNT network is active enough to allow long range charge evacuation, enabling the use of alginate/CNT beads as soft 3D electrodes. Direct connection or local interrogation by a microelectrode allows visualization of their communication as a network and eventually the study of them individually at the nanoscale.
Domain Coarsening in a Two-Dimensional Binary Mixture: Growth Dynamics and Spatial Correlations (1994)

Late-stage coarsening in a 2D binary mixture has been investigated via direct imaging of "bubble" domains in an amphiphilic monolayer at an air-water interface. In a regime with growth exponent $n\ensuremath{\simeq}0.28$ for the mean domain radius, the radius distribution exhibits dynamic scaling, closely approaching a Gaussian shape. The local structure of disordered bubble patterns ensures short-range screening of topological charge. Pattern statistics correspond to equilibrated random Voronoi lattices and indicate a prominent role of entropy maximization. Pattern stabilization against bubble coalescence is attributed to electrostatic interactions.
Experimental and Numerical Studyof an Earth-to-Air Heat Exchangerin Northeastern Poland (2018)

Our paper presents empirical data from a laboratory experiment investigating the performance of an air-to-soil heat exchanger between July and August 2016. Measurements were performed in a laboratory of the Department of Civil Engineering and Building Engineering Physics of the University of Warmia and Mazury in Olsztyn. Empirical data were compared with the results of analytical calculations based on meteorological data for a typical meteorological year.
A Portable Operating System Interface and Utility Library (1986)

OSSI provides the interface missing between Modula-2 and system-dependent I/O operations. It can be ported between systems with minimal changes.
Design and kinetic characterization of multisubstrate inhibitors of dopamine .beta.-hydroxylase (1986)

The synthesis and kinetics characterization of a new class of dopamine beta-hydroxylase (DBH; EC 1.14.17.1) inhibitor, 1-(4-hydroxybenzyl)imidazole-2-thiol, is reported. These inhibitors, which incorporate a phenethylamine substrate mimic and an oxygen mimic into a single molecule, exhibit both the kinetic properties and the potency (Kis approximately 10(-9) M) expected for a multisubstrate inhibitor and are therefore classified as such. Steady-state kinetic experiments with these multisubstrate inhibitors and their substructural analogues support the recently proposed pH-dependent changes in substrate binding order [Ahn, N., & Klinman, J. P. (1983) Biochemistry 22, 3106] and a mechanism whereby the inhibitor binds specifically to the reduced Cu+ form of enzyme at both the phenethylamine substrate site and the active-site copper atom(s). A Yonetani-Theorell double-inhibition experiments indicates mutually exclusive binding of the inhibitor substructures p-cresol and 1-methylimidazole-2-thiol to suggest an extremely short intersite distance between the phenethylamine binding site and the active-site copper atom(s).
Calculations of Doppler Radar Velocity Spectrum Parameters for a Mixture of Rain and Hail (1976)

The radar reflectivity factors, the reflectivity-weighted mean terminal velocities (VT), and the standard deviations (σv) of the resulting Doppler spectra, were computed for specified size distributions of rain, dry and wet ice spheres (taken to be hailstones), and rain with hail. Unambigous estimates of the mean velocity and standard deviation can be obtained from a radar measurement of reflectivity for rain alone and for dry ice spheres as a function of maximum sphere size. The results for wet ice spheres are strongly dependent on the thickness of the liquid water coating on the ice core. When rain and hail coexist, large values of reflectivity are associated with large ranges of VT and σv. If the shape of the hail size distribution is known, an independent measurement of the maximum hailstone diameter or a knowledge of the standard deviation of the observed Doppler velocity spectrum can reduce the uncertainty in estimates of VVT.
Cleavage Reactions of Penicillin Nuclei with Seyferth Reagents (1989)

Scission avec PhHgCX 3 : obtention d'α-isopropylidene dihalogenomethylthio-2 oxo-4 azetidine acetates-1
On the stability of the DC and RF gain of GaInP/GaAs HBTs (2002)

In the present work the reliability of Carbon-doped GaInP/GaAs HBTs is evaluated by means of a current stress performed at room temperature. The impact of the stress on DC and RF characteristics and low frequency noise is reported, and a correlation between DC, RF, and noise variations is demonstrated. The effects observed are explained in terms of Carbon passivation by Hydrogen atoms released from passivation/semiconductor interface during the stress.
β‐Lithio Ketone Enolates: Generation and Reactions with Electrophiles (1991)

Deprotonation and Sn/Li exchange transforms the ketone 1 into the title compound 2, which proves to be a most useful synthesis step. The α,β-dianions of ketones react with electrophiles, whereby two different electrophiles can react sequentially.
Building Elastin: Incorporation of Recombinant Human Tropoelastin into Extracellular Matrices using Nonelastogenic Rat-1 Fibroblasts as a Source for Lysyl Oxidase (2001)

The purpose of this study was to assess the feasibility of crosslinking exogenously produced tropoelastin, the precursor of insoluble elastin, into existing elastin. Tritiated recombinant human tropoelastin (rhTE) was added to neonatal rat aorta smooth-muscle cell (NNRSMC) cultures. As much as 12% of the added rhTE was incorporated into the NNRSMC-derived insoluble elastin with the formation of the elastin crosslinks desmosine (DES) and isodesmosine (IDES) in a time-dependent fashion. The ratio of radioactivity found in DES and IDES crosslinks to that found in lysyl residues increased from 0.18 immediately after incubation with rhTE to 0.76 after 14 d. Crosslinking of rhTE into elastin and the accompanying formation of tritiated water was inhibited by beta-aminoproprionitrile, a potent inhibitor of lysyl oxidase, an enzyme critical for the post-translational processing of elastin and collagen. Acellular NNRSMC matrices were produced and replated with Rat-1 fibroblasts, cells that were found to express lysyl oxidase but not tropoelastin. At 14 d after incubation with rhTE, the ratio of DES and IDES radioactivity to that of lysine in the insoluble elastin was 0.38. We show for the first time that cells expressing lysyl oxidase, but not elastin, as well as elastogenic cells can incorporate rhTE into insoluble elastin with the formation of elastin crosslinks. This novel approach might be used to augment elastin repair in certain pathologic states.
Drug loaded magnetic nanoparticles for cancer therapy (2006)

Magnetic nanoparticles have been investigated for biomedical applications for more than 30 years. In medicine they are used for several approaches such as magnetic cell separation or magnetic resonance imaging (MRI). The development of biocompatible nanosized drug delivery systems for specific targeting of therapeutics is the focus of medical research, especially for the treatment of cancer and diseases of the vascular system. In an experimental cancer model, we performed targeted drug delivery and used magnetic iron oxide nanoparticles, bound to a chemotherapeutic agent, which were attracted to an experimental tumour in rabbits by an external magnetic field (magnetic drug targeting). Complete tumour remission could be achieved. An important advantage of these carriers is the possibility for detecting these nanoparticles after treatment with common imaging techniques (i.e. x-ray-tomography, magnetorelaxometry, magnetic resonance imaging), which can be correlated to histology.
Synthesis of Partially Reduced Graphene Oxide/Silver Nanocomposite and Its Inhibitive Action on Pathogenic Fungi Grown Under Ambient Conditions (2016)

Abstract In the present study partially reduced graphene oxide‐ Silver Nanocomposite (GO−Ag NC) was chemically synthesized by using graphene oxide as a precursor and simultaneously its antimicrobial property is studied. Results indicate growth inhibition of fungi belonging to phylum Zygomycota as well as several types of microbes grown under open environment at ambient conditions in Luria Bertani Agar medium. SEM and HRTEM images represent highly exfoliated r GO layers with Silver Nanoparticles embedded on r GO flakes indicating the formation of r GO−Ag Nanocomposite. XRD and Raman spectroscopy confirmed the formation of good quality GO flakes and r GO−Ag Nanocomposite. XPS confirmed intercalation of Graphite by Oxygen containing functional groups, confirming the oxidation of Graphite and corresponding changes in functional groups introduced by the inclusion of Ag Nanoparticles. FTIR and UV‐Vis Spectroscopy confirm the formation of good quality GO, r GO, r GO−Ag Nanocomposite. The behaviour of the silver ion release from the r GO−Ag NC was studied in an acidic solution.Comparative study to see the effect of GO, r GO and Ag Nanoparticles were also carried out on microbes. SEM images of fungi shows destruction of microbial cell membrane.
Propagation of electrical spiking activity along the small intestine: intrinsic versus extrinsic neural influences. (1979)

1. The electrical activity of the small intestine of conscious dog, recorded by means of chronically implanted electrodes, was related to the transit time estimated by phenol red infusion and its propagation observed after a single or double transection and following either isolation or removal of a 50 cm jejunal loop. 2. In the fasted dog, the activity was characterized by the propagation of myoelectric complexes at a velocity of 4 cm/min during which the mean transit time averaged 13 min/m. About 2/3 of these complexes were seen to pass beyond a single section and anastomosis of the jejunum with a delay of 15 min. This number was reduced to 1/3 and the delay doubled when a second section was performed 50 cm distally. 3. In dog with an isolated jejunal loop, most of the myo-electric complexes were seen to pass from the proximal intestine to the loop and then to the intestine beyond the sit of anastomosis within 37 min. Some complexes however passed directly through the anastomosis within 30-32 min, affecting or not the loop. Others started on the loop and/or on the intestine beyond the anastomosis. Finally, the total number of complexes recorded on the distal jejunum was greater than on the duodenum, an effect which disappeared after removal of the isolated loop. 4. The propagation of the complexes occurred at a lower velocity after denervation of a jejunal segment in situ but was arrested in the case of an isolated-denervated jejunal loop. 5. It is concluded that continuity of structures in the bowel is essential for the propagation of a myo-electric complex which is stopped and replaced by another complex at the level of an anastomosis, the number os complexes reorganized beyond an anastomosis and their velocity of propagation depending upon both intrinsic and extrinsic neural influences.
Bifurcation/chaos and their practical relevance to chemical and biological systems (2014)

Bifurcation and chaos are important phenomena affecting many physical and chemical systems. They are also related to the stability/instability and multiplicity phenomena associated with these systems. The phenomena are not only of theoretical/mathematical interest but are also important for laboratory, pilot plant and commercial units. This paper concentrates on 3 systems: 1. The novel auto-thermic Circulating Fluidized Membrane Steam Reformer (CFBMSR) for the efficient production of the clean fuel hydrogen and which shows multiplicity of the steady state (static bifurcation). 2. A novel fermentor for the efficient production of bio-ethanol that shows static/dynamic bifurcation as well as chaotic behaviour. 3. The neurocycle of the acetylcholine transmitter in the brain using diffusion-reaction models in order to gain insight into their possible connection to Alzheimer and Parkinson Diseases (AD/PD); these are preliminary efforts to investigate the bifurcation and chaotic behaviour of this neurocycle.
Nivolumab in Resected and Unresectable Metastatic Melanoma: Characteristics of Immune-Related Adverse Events and Association with Outcomes (2015)

Cutaneous irAEs are associated with improved survival in melanoma patients treated with nivolumab, and clinical benefit should be validated in larger prospective analyses.
Al 2 O 3 prepared by atomic layer deposition as gate dielectric on 6H-SiC(0001) (2003)

Al 2 O 3 films were deposited as alternative gate dielectric on hydrogen-terminated 6H-SiC(0001) by atomic layer chemical vapor deposition and characterized by photoelectron spectroscopy (PES) and admittance measurements. The PES results indicate an abrupt interface free of significant Si–suboxide contributions where the Al2O3 layer is connected to SiC by bridging oxygen atoms. The admittance measurements yield an interface state density which is lower than that of the thermally formed oxide and show in particular no increase toward the conduction band edge. Furthermore, a nearly symmetrical band alignment of Al2O3 on 6H-SiC with offsets of 2.2 and 1.8 eV is determined for the valence and conduction bands, respectively. This makes Al2O3 a serious competitor to thermal oxides as gate insulator in SiC devices.
Are asthma-like symptoms in elite athletes associated with classical features of asthma? (2009)

Asthma-like symptoms in elite athletes are not necessarily associated with classic features of asthma and alone should not give a diagnosis of asthma. More studies are needed to further investigate if and how the asthma phenotype of elite athletes differs from that of classical asthma.
Synthesis and antimicrobial activity of some 2-[1-(4-oxo-3,4-dihydrophthalazine-1-yl)alkyl]-1H-isoindole-1,3(2H)-dione and their imidoxy derivatives (2007)

In this study, a series of 2-[(4-substituted phthalazine-1