gebhart/patrepeval huggingface dataset:
Molecular Structures and Photophysical Properties of Dirhodium Fluorophosphine Complexes (1996)

The excited state properties of a series of singly bonded dirhodium compounds, consisting of Rh(0)(2), Rh(0)Rh(II)X(2), and Rh(II)(2)X(4) (X = Cl and Br) cores coordinated by three bis(difluorophosphino)methylamine ligands, have been investigated. The newly synthesized complexes with X = Br have been structurally characterized. The mixed-valence complex Rh(2)[&mgr;-CH(3)N(PF(2))(2)](3)Br(2)[(PF(2))CH(3)N(PF(2))] crystallizes in the orthorhombic space group P2(1)2(1)2(1) with a = 13.868(7) Å, b = 16.090(5) Å, c = 11.614(5) Å, V = 1591(3) Å(3), and Z = 4; the structure was refined to values of R = 0.052 and R(w) = 0.062. Orange crystals of Rh(2)[&mgr;-CH(3)N(PF(2))(2)](3)Br(4) are monoclinic with a C2/c space group: a = 14.62(6) Å, b = 12.20(2) Å, c = 14.33(1) Å; beta = 106.0(2) degrees; V = 2457(11) Å(3); Z = 4; and R = 0.058 and R(w) = 0.056. Crystalline solids and low-temperature glasses of each member of the chloride and bromide series exhibit long-lived red luminescence. Excitation profiles and temperature dependencies of the emission bandwidths and lifetimes for all complexes are characteristic of luminescence originating from a dsigma excited state. Efficient nonradiative decay is observed upon the thermal population of an excited state proximate to the lowest energy emissive excited state of these complexes. The nonradiative decay rate constant of the upper excited state is 10(2)-10(3) and 10(3)-10(4) greater than that of the emissive excited state for complexes with X = Cl and Br, respectively.
A ferrocene crown ether–functionalized polypyrrole film electrode for the electrochemical recognition of barium and calcium cations (1997)

Transfer of the recognition activity of a ferrocene ionophore to an electrode surface from the homogeneous phase has been successfully accomplished for the first time. The synthesis and electrochemical characterization of a new pyrrole‐substituted ferrocene crown ether are described, followed by the formation of the corresponding polymer film modified electrode. It is shown that the electrode exhibits amperometric recognition in an organic solvent of Ca 2⊕ and Ba 2⊕ among the alkaline and alkaline earth metal cations.
TXL: a rapid prototyping system for programming language dialects (2003)

A rapid prototyping system for extensions to an existing programming language is described. Such extensions could include language features or could introduce notation specific to a particular problem domain. The system consists of a dialect description language used to specify the syntax and semantics of extensions and a context-sensitive syntactic transducer that automatically implements the extensions by transforming source programs written using them to equivalent programs in the original unextended language. Because the transformer is context-sensitive, it is more powerful than traditional context-free preprocessors and extensible languages, and can be used to prototype language extensions involving significantly novel programming paradigms such as object-oriented programming.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Extraction and quantification of amino acids in human stratum corneum <i>in vivo</i> (2010)

It follows that reverse iontophoresis is useful for quantifying AAs in the SC and these data are highly correlated with levels obtained by tape stripping. However, reverse iontophoresis is impractical for the routine monitoring of AA plasma concentrations (unlike the situation for glucose, the skin reservoir of which is much smaller).
Adaptive control of kinematically redundant robots (1997)

A redundant robot has more degrees of freedom than those needed to position the Robert end-effector uniquely. In a usual robotic task, only end-effector position trajectory is specified. The joint position trajectory is unknown, and it must be selected from a self-motion manifold for a specified end-effector. In many situations, the robot dynamic parameters such as the link mass, inertia, and joint viscous friction are unknown. The lack of knowledge of the joint trajectory and the dynamic parameters make it difficult to control redundant robots. In this paper we show, through careful formulation of the problem, that the adaptative control of redundant robots can be addressed as a reference-velocity traking problem in the joint space. A control law ensures bounded estimation of the unknown dynamic parameters of the robot, and the convergence to zero of the velocity traking error is derived. To ensure the joint motion on the self-motion manifold remains bounded, a homeomorphic transformation is found. This transformation decomposes the dynamics of the velocity tracking error into a cascade system consisting of the dynamics in the end-effector error coordinates and the dynamics on the self-motion manifold. The dynamics on the self-motion manifold is shown to be related to the concept of zero dynamics. In the shown that, if the reference joint trajectory is selected to optimize a certain type of objective function, then stable dynamics on the self-motion manifold result. This ensures the overall stability of the adaptive system. Detailed simulations are given to test the theoretical developments. The proposed adaptive scheme does not require measurements of the joint acceleration or the inversion of the inertia matrix of the robot.
Delayed closure effect in preterm infants with patent ductus arteriosus (2008)

Purpose : This study aims to determine whether early closure (within 7 d) of significant patent ductus arteriosus (PDA) with indomethacin or ligation reduces neonatal morbidity when compared with delayed closure (after 7 d). Methods : Fifty-eight extremely-low-birth-weight infants admitted to the NICU of Seoul National University Hospital from April 2005 to May 2007 with PDA were studied retrospectively. Results : The mean gestational age (GA) was 26±2 weeks (range, 23-32 wk), and the birth weight was 782±146 g (range, 430-990 g). The delayed closure group was associated with early GA (25.7±1.7 wk vs. 27.1±2.0 wk, P=0.013), in vitro fertilization (IVF) (55% vs 24%, P=0.017), and the absence of preeclampsia (5% vs. 34%, P=0.013). There was no difference in ductal size between the early closure and delayed closure groups. The incidence of bronchopulmonary dysplasia (95% vs 65%, P=0.012) and intraventricular hemorrhage (70% vs. 39%, P=0.027) increased in the delayed closure group. Using regression analysis adjusted for gestational age, delayed closure correlated positively with the duration of ventilator support (P=0.008), hospitalization (P=0.020), time to full enteral feeding (P
Introduction to Network Security (2008)

This chapter contains sections titled: Goals of cryptographic protocols Basics and terminology Attack types Defense mechanisms Security protocols Weak authentication techniques Secure DNS
Abstract 121: Identification of tumor suppressive microRNAs in maxillary sinus squamous cell carcinoma based on microRNA expression signature (2011)

Abstract Maxillary sinus squamous cell carcinoma (MSSCC) comprises 2-3% of all cancers of head and neck tumor and the annual incidence rate is 0.5-1.0 per 100,000 populations. After introduction of multimodality treatment comprising radiation therapy along with concomitant intra-arterial chemotherapy, rates of local control was improved. However the prognosis of advanced MSSCC is still worse. The 5-years survival rate of T4 tumors is 50% around. Local recurrence is the most common cause of treatment failure and death. Greater understanding of the molecular oncogenic pathways in MSSCC could help improve diagnosis, therapy, and prevention of the disease. MicroRNAs (miRNAs), non-coding RNA 21-25 nucleotides in length, regulate gene expression primarily at the posttranscriptional level. Growing evidence suggests that miRNAs are aberrantly expressed in many human cancers, and that they play significant roles in carcinogenesis and cancer progression. The expression signature of cancer related miRNAs could contribute as useful biomarkers for diagnosis and improvement of prognosis for MSSCC. No studies have been carried out for the purpose of identifying specific miRNA alterations in MSSCC. In this study, we performed the miRNA expression signature specific to MSSCC by evaluating 749 mature miRNAs expressions in 5 matched pairs of MSSCC tissues and normal maxillary sinus epithelium. A subset of 9 miRNAs was significantly down-regulated in our signature. Gain-of-function analysis revealed that miR-874 was significantly inhibited cell proliferation, suggesting miR-874 has a tumor suppressive function in MSSCC. We are continuing a search of target genes of miR-874 by using genome-wide gene expression analysis. The identification of tumor suppressive miRNAs and their target genes could provide new insights into potential mechanism of MSSCC carcinogenesis. Citation Format: {Authors}. {Abstract title} [abstract]. In: Proceedings of the 102nd Annual Meeting of the American Association for Cancer Research; 2011 Apr 2-6; Orlando, FL. Philadelphia (PA): AACR; Cancer Res 2011;71(8 Suppl):Abstract nr 121. doi:10.1158/1538-7445.AM2011-121
Biliary tract motility and its relationship to clinical disorders. (1990)

Biliary tract motility and its relationship to clinical disorders.W J DoddsAudio Available | Share
1403 Flow-induced structure change of CTAB/NaSal aqueous solution in sinusoidal shear flow (2007)

Flow-induced structure change of a surfactant solution caused by sinusoidal shear flow was investigated. An aqueous solution of CTAB/NaSal is used as a test fluid and it is known that this surfactant makes wormlike micelles and it causes flow-induced structure change in step shear. In this experiment, it is found that the sinusoidal shear strain also causes shear-induced structure change and the appearance condition of critical shear strain and shear rate is almost the same measured by step shear. The maximum shear stress at the first period is very high and it decreases at the following period. The relaxation time of this reducing maximum shear stress was evaluated and it is found that it is decreasing with increasing angular frequency and with increasing the maximum strain.
Characterisation and measurement of silicon solar cells with floating junction passivation (2002)

Theoretical and experimental demonstrations have shown that excellent rear surface passivation can be attained by using a floating junction. The extent to which the rear is passivated, however, can be difficult to ascertain, particularly when there exist parasitic shunts across the floating junction. This paper presents a new experimental technique suitable for bifacial floating junction solar cells, that determines two key parameters associated with the rear: the fraction of current transferred from the rear to the front, and the magnitude of the parasitic shunt resistance. In the latter case, either a local or an averaged value can be found. Measurements on floating junction buried contact solar cells show that the shunt resistance in buried contact solar cells can be over 1 M/spl Omega/.
X-ray photoemission study of CoFeB∕MgO thin film bilayers (2007)

The authors present results from an x-ray photoemission spectroscopy study of CoFeB∕MgO bilayers where they observe process-dependent formation of B, Fe, and Co oxides at the CoFeB∕MgO interface due to oxidation of CoFeB during MgO deposition. Vacuum annealing reduces the Co and Fe oxides but further incorporates B into the MgO forming a composite MgBxOy layer. Inserting an Mg layer between CoFeB and MgO introduces an oxygen sink, providing increased control over B content in the barrier.
Efficacy of oleylphosphocholine (Ol<scp>PC</scp>) <i>in vitro</i> and in a mouse model of invasive aspergillosis (2015)

Invasive aspergillosis (IA) has become increasingly common and is characterised by high morbidity and mortality. Upcoming resistance threatens treatment with azoles and highlights the continuous need for novel therapeutics. This laboratory study investigated the in vitro and in vivo potential of the alkylphospholipid oleylphosphocholine (OlPC) against Aspergillus. In vitro activities of OlPC, miltefosine, posaconazole and voriconazole were determined for Aspergillus fumigatus, A. niger, A. terreus and A. flavus. In vivo efficacy of OlPC was evaluated in a systemic A. fumigatus mouse model, adopting a short-term and long-term oral or intraperitoneal dosing regimen. OlPC showed good in vitro activity against A. fumigatus (IC50 = 1.04 μmol l(-1)). Intraperitoneal administration of 50 mg kg(-1) day(-1) OlPC significantly reduced the fungal organ burdens at 4 days post-infection (dpi). Although 5- and 10-day OlPC treatment improved survival, organ burdens were not affected at 10 and 15 dpi. While this study showed excellent in vitro activity of OlPC against Aspergillus spp., its therapeutic efficacy in an acute mouse model for IA was less convincing. Given the limited therapeutic options in the current antifungal market for invasive infections, OlPC activity should be assessed in a less stringent in vivo model, potentially in combination treatment with other already marketed antifungal drugs.
Long-term follow-up of anti-CD19 CAR T-cell therapy for B-cell lymphoma and chronic lymphocytic leukemia. (2020)

3012 Background: T cells expressing anti-CD19 chimeric antigen receptors (CARs) can cause complete remissions of relapsed lymphoma. We conducted the first clinical trial of anti-CD19 CAR T cells to show responses against lymphoma. This CAR was later developed as axicabtagene ciloleucel. Here, we aimed to assess the long-term durability of remissions and the long-term adverse effects after anti-CD19 CAR T-cell therapy. Methods: Between 2009 and 2015, we treated 43 patients with anti-CD19 CAR T cells preceded by conditioning chemotherapy of cyclophosphamide plus fludarabine (NCT00924326). Three patients were re-treated for a total of 46 CAR T-cell treatments. Twenty-eight patients had aggressive lymphoma (diffuse large B-cell lymphoma or primary mediastinal B cell lymphoma), eight patients had low-grade lymphoma (five with follicular lymphoma and 1 each with splenic marginal zone lymphoma, mantle cell lymphoma, and unspecified low-grade non-Hodgkin lymphoma), and seven patients had chronic lymphocytic leukemia (CLL). Patients were treated in three cohorts that differed in the CAR T-cell production process and conditioning chemotherapy dose. Results: Of the 43 treated patients, 63% had chemotherapy-refractory lymphoma. Patients had received a median of 4 previous lines of therapy. The median CAR + T cell dose per kilogram was 2X10^6. The overall remission rate was 76% with 54% complete remissions (CR) and 22% partial remissions (PR). Patients with CR had higher median peak blood CAR levels (86 CAR + cells/µL) than those who did not have CR (16 CAR + cells/µL, P= 0.0041). Long-term adverse effects were rare except for B-cell depletion and hypogammaglobulinemia, which both improved over time. Conclusions: This is the longest follow-up study of patients who received anti-CD19 CAR T cells. Anti-CD19 CAR T cells cause highly durable remissions of relapsed B-cell lymphoma and CLL, and long-term adverse effects of anti-CD19 CAR T cells were rare and usually mild. Clinical trial information: NCT00924326 . [Table: see text]
Endothelial Function Varies According to Insulin Resistance Disease Type (2007)

Among these different types of patients with insulin resistance, we found abnormal endothelium-dependent vasodilation only in the patients with type 2 diabetes. We postulate that variations in the mechanism of insulin resistance may affect endothelial function differently than glucose homeostasis.
Automatic delay controller (1987)

An automatic delay controller is described for a system for radiographic recording of high-speed processes whose speed varies from experiment to experiment. The controller has been used with a MIRA-5B/1 source of single x-ray pulses. The controller is implemented by integrated circuits of series 155 and permits discrete variation of the trigger-pulse delay in the range of (1-16)H, where H is the distance between the detectors of the phase of the high-speed process. The accuracy of locking of the trigger pulse of the x-ray radiator onto a given phase of the process under study is 1 ..mu..sec. The trigger-pulse delay range is 0-999 ..mu..sec.
Redatuming through a salt canopy and target-oriented salt-flank imaging (2008)

Abstract We describe a new shortcut strategy for imaging the sediments and salt edge around a salt flank through an overburden salt canopy. We tested its performance and capabilities on 2D synthetic acoustic seismic data from a Gulf of Mexico style model. We first redatumed surface shots, using seismic interferometry, from a walkaway vertical seismic profile survey as if the source and receiver pairs had been located in the borehole at the positions of the receivers. This process creates effective downhole shot gathers by completely moving surface shots through the salt canopy, without any knowledge of overburden velocity structure. After redatuming, we can apply multiple passes of prestack migration from the reference datum of the bore-hole. In our example, first-pass migration, using only a simple vertical velocity gradient model, reveals the outline of the salt edge. A second pass of reverse-time, prestack depth migration using full two-way wave equation was performed with an updated velocity model that consisted of the velocity gradient and salt dome. The second-pass migration brings out dipping sediments abutting the salt flank because these reflectors were illuminated by energy that bounced off the salt flank, forming prismatic reflections. In this target-oriented strategy, the computationally fast redatuming process eliminates the need for the traditional complex process of velocity estimation, model building, and iterative depth migration to remove effects of the salt canopy and surrounding overburden. This might allow this strategy to be used in the field in near real time.
Effects of Fuel Injection Conditions and Ambient Gas Conditions on Auto-ignition and Combustion of Hydrogen Jet (2002)

It is thought that hydrogen diesel engine for an inert gas recirculating co-generation system, was proposed by WE-NET project, has potential for a high efficiency and zero emission. To accomplish the optimum performance of this direct-injection gaseous fuel engine, the characteristics of the auto-ignition and combustion processes in hydrogen jet have to be understood. In this research, the ignition delay and rate of heat release of hydrogen jet were measured in a constant-volume combustion vessel with a hydraulically actuated gas injector under simulated direct-injection diesel engine-like conditions in order to clarify the effects of the injection conditions, the ambient gas temperature and oxygen concentration.
Optimal multitone bit allocation for fixed-rate video transmission over ADSL (2002)

In this paper we propose a novel approach for the bit allocation performed in an ADSL modulator. This new method is based on the observation that the transmission speed using ADSL strongly depends on the distance between the central office and the subscriber's side and does not permit real-time transmission for high bitrate video on long distances. The algorithm we develop takes into account the characteristics of a video sequence and distributes the channel error according to visual sensitivity. This method involves variable transmission Bit Error Rate.
Macroscale lattice‐Boltzmann methods for low Peclet number solute and heat transport in heterogeneous porous media (2010)

This paper introduces new methods for simulating subsurface solute and heat transport in heterogeneous media using large‐scale lattice‐Boltzmann models capable of representing both macroscopically averaged porous media and open channel flows. Previous examples of macroscopically averaged lattice‐Boltzmann models for solute and heat transport are only applicable to homogeneous media. Here, we extend these models to properly account for heterogeneous pore‐space distributions. For simplicity, in the majority of this paper we assume low Peclet number flows with an isotropic dispersion tensor. Nevertheless, this approach may also be extended to include anisotropic‐dispersion by using multiple relaxation time lattice‐Boltzmann methods. We describe two methods for introducing heterogeneity into macroscopically averaged lattice‐Boltzmann models. The first model delivers the desired behavior by introducing an additional time‐derivative term to the collision rule; the second model by separately weighting symmetric and anti‐symmetric components of the fluid packet densities. Chapman‐Enskog expansions are conducted on the governing equations of the two models, demonstrating that the correct constitutive behavior is obtained in both cases. In addition, methods for improving model stability at low porosities are also discussed: (1) an implicit formulation of the model; and (2) a local transformation that normalizes the lattice‐Boltzmann model by the local porosity. The model performances are evaluated through comparisons of simulated results with analytical solutions for one‐ and two‐dimensional flows, and by comparing model predictions to finite element simulations of advection isotropic‐dispersion in heterogeneous porous media. We conclude by presenting an example application, demonstrating the ability of the new models to couple with simulations of reactive flow and changing flow geometry: a simulation of groundwater flow through a carbonate system.
Effects of warfarin at beginning doses on patients with valve replacement. (1992)

Warfarin administered to patients with valve replacement at a dose of 0.1 mg/kg for 2 days after surgery, and blood levels of warfarin, TT, PT, HPT, total vitamin K and vitamin K1-epoxide were determined at various time intervals after the administration of the drug. The measurements were obtained from 15 patients: 8 patients with AVR, 6 patients with MVR, and 1 patient with DVR. The blood levels of warfarin reached a peak of 462 +/- 160 ng/ml 6 hours after the administration, TT, PT and HPT were 40% of the initial values 24 hours after the administration, and vitamin K1-epoxide was 1.28 +/- 0.30 ng/ml 24 hours after the administration. It is clear from the results that warfarin exhibits sufficient anticoagulant effects at a beginning dose of 0.1 mg/kg after surgery to prevent a sudden decrease in blood coagulation.
Effect of prenatal exposure to oestrogen on quality of semen: comparison of twins and singleton brothers (2002)

Some have argued that industrial funding has undue influence on the research agenda. 10 Others state that a
CMOS system-on-a-chip voltage scaling beyond 50nm (2000)

The limits on CMOS energy dissipation imposed by subthreshold leakage currents and by wiring capacitance are investigated for CMOS generations beyond 50nm at NTRS projected local and global clock rates for high performance processors. Physical short-channel MOSFET models that consider high-field effects, threshold voltage roll-off and reverse subthreshold swing roll-off are employed in tandem with stochastic interconnect distributions to calculate optimal supply voltage, threshold voltage and gate sizes that minimize total CMOS power dissipation by exploiting trade-offs between saturation drive current and subthreshold leakage current and between device size and wiring capacitance. CMOS power dissipation at its lower limit, increases exponentially with clock frequency imposing limits on performance set by heat removal. Heat removal constraints at high local clock rates, limiting the average wire length and device size within a local zone of synchrony, or macrocell, in a short-wire cellular array architecture are used to project the maximum macrocell size and count for generations beyond 100nm.