gebhart/patrepeval huggingface dataset:
Fragile X‐associated primary ovarian insufficiency: evidence for additional genetic contributions to severity (2008)

The fragile X mental retardation gene (FMR1) contains a CGG repeat sequence in its 5' untranslated region that can become unstable and expand in length from generation to generation. Alleles with expanded repeats in the range of approximately 55-199, termed premutation alleles, are associated with an increased risk for fragile-X-associated primary ovarian insufficiency (FXPOI). However, not all women who carry the premutation develop FXPOI. To determine if additional genes could explain variability in onset and severity, we used a random-effects Cox proportional hazards model to analyze age at menopause on 680 women from 225 families who have a history of fragile X syndrome and 321 women from 219 families from the general population. We tested for the presence of a residual additive genetic effect after adjustment for FMR1 repeat length, race, smoking, body mass index, and method of ascertainment. Results showed significant familial aggregation of age at menopause with an estimated additive genetic variance of 0.55-0.96 depending on the parameterization of FMR1 repeat size and definition of age at menopause (P-values ranging between 0.0002 and 0.0027). This is the first study to analyze familial aggregation of FXPOI. This result is important for proper counseling of women who carry FMR1 premutation alleles and for guidance of future studies to identify additional genes that influence ovarian insufficiency.
Psychology and U.S. psychologists in torture and war in the Middle East. (2006)

The involvement of U.S. psychologists and their influence on torture in Cuba, Afghanistan and Iraq provides previously unrevealed evidence of U.S. torture and military tactical policy, and points to probable military goals the U.S. Administration has denied. What is revealed is that current torture has been designed and used, not so much for interrogation as the Administration and the media insist, but for control by terror. Further, Iraqi civilian deaths may be deliberate and for the same purpose. That is, discovery of involvement of the U.S. psychological professions is a clue to torture, and perhaps killing, as policy, not accident.
Congo Virus from Domestic Livestock, African Hedgehog, and Arthropods in Nigeria (1970)

Thirty-four strains of Congo virus, an agent previously unrecognized in West Africa, were recovered from vertebrate and arthropod material collected in Nigeria during arbovirus investigations in the period July 1964 through December 1968. All isolations were made in infant mice. Five of the strains came from the blood of market animals; one from pooled liver and spleen of the hedgehog. Atelerix albiventris; 27 from ticks (four species of Hyalomma, Amblyomma variegatum, and Boophilus decoloratus); and one from Culicoides spp. The behavior of the strains in infant mice is described. A female Hyalomma rufipes that had engorged on an experimentally infected calf was found positive for Congo virus 18 days after dropping and 24 days after viremia was last detected in the calf.
Orthokinetic destabilization of a protein-stabilized emulsion by a water-soluble surfactant (1993)

The coalescence rate of liquid droplets in a protein-stabilized emulsion containing water-soluble non-ionic surfactant has been studied in turbulent shear flow by monitoring the change in average droplet size with shearing time. The pronounced effect on orthokinetic stability of small surfactant additions may be attributed to increased adsorbed layer mobility without significant protein displacement from the interface.
Solid-State Maser Amplifier (1958)

The operation of a solid-state maser amplifier at 2800 Mc/sec is described. A dual-frequency cavity containing paramagnetic potassium chromicyanide in an isomorphous cobalt diluent is used at 1.25\ifmmode^\circ\else\textdegree\fi{}K. The experimental observations of the maser both as an amplifier and as an oscillator are compared with theory.
Green tea - A short review (2018)

Green tea, which is produced from the leaves of the Camellia sinensis plant and belongs to the family Theaceae, is one of the most popular beverages worldwide. Over the past 30 years or more, scientists have studied this plant in respect to potential health benefits. The health benefits of green tea for a wide variety of ailments, including different types of cancer, heart disease, and liver disease, were reported. Many of these beneficial effects of green tea are related to its catechin, particularly (-)-epigallocatechin-3-gallate, content. There is evidence from in vitro and animal studies on the underlying mechanisms of green tea catechins and their biological actions. There are also human studies on using green tea catechins to treat metabolic syndrome, such as obesity, type II diabetes, and cardiovascular risk factors. Long-term consumption of tea catechins could be beneficial against high-fat diet-induced obesity and type II diabetes and could reduce the risk of coronary disease. This review is done to spread awareness among general population about the benefits of green tea.
Living at Micro Scale: The Unexpected Physics of Being Small (2009)

Kermit the Frog famously said that it isn't easy being green, and in Living at Micro Scale David Dusenbery shows that it isn't easy being small - existing at the size of, say, a rotifer, a tiny multicellular animal just at the boundary between the visible and the microscopic. 'Imagine,' he writes, 'stepping off a curb and waiting a week for your foot to hit the ground.' At that scale, we would be small enough to swim inside the letter O in the word 'rotifer.' What are the physical consequences of life at this scale? How do such organisms move, identify prey and predators and (if they're so inclined) mates, signal to one another, and orient themselves? In clear and engaging prose, Dusenbery uses straightforward physics to demonstrate the constraints on the size, shape, and behavior of tiny organisms. While recounting the historical development of the basic concepts, he unearths a corner of microbiology rich in history, and full of lessons about how science does or does not progress. Marshalling findings from different fields to show why tiny organisms have some of the properties they are found to have, Dusenbery shows a science that doesn't always move triumphantly forward, and is dependent to a great extent on accident and contingency.
[Three cases of laryngeal mycosis]. (2005)

喉真菌病少见,以前仅有散发报告,而近几年其发病率似有上升趋势,为进一步提高对该病的认识,探讨对该病的诊断及治疗,现对我科1998年至2002年收治喉真菌病的临床资料作一分析,并对参阅资料作回顾性分析.
Design for reliability: the major challenge for VLSI (1993)

Selected integrated circuit (IC) reliability issues are discussed within the context of the design-in reliability concept. The electrical reliability issues discussed are latchup, electrostatic discharge, hot carrier effects, thin dielectric breakdown, and electromigration. Examples of the environmental reliability issues discussed are alpha -particle induced soft errors, thermal stress, mechanical stress, and corrosion.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Latency Aware and Service Delay with Task Scheduling in Mobile Edge Computing (2018)

In a traditional Mobile Cloud Computing (MCC), a stream of data produced by mobile users (MUs) is uploaded to the remote cloud for additional processing throughout the Internet. Though, due to long WAN distance it causes high End to End latency. With the intention of minimize the average response time and key constrained Service Delay (network and cloudlet Delay) for mobile users (MUs), offload their workloads to the geographically distributed cloudlets network, we propose the Multi-layer Latency Aware Workload Assignment Strategy (MLAWAS) to allocate MUs workloads into optimal cloudlets, Simulation results demonstrate that MLAWAS earns the minimum average response time as compared with two other existing strategies.
Disorders of the sleep–wake cycle in adults (1998)

Adults have an intrinsic body clock which regulates a complex series of rhythms including sleep and wakefulness, fatigue and cognitive ability. This endogenous clock naturally runs more slowly than the solar day and is entrained to a 24-h rhythm primarily by the alternation of light and darkness. Jet lag, shift-work sleep disorder, and some of the chronic insomnias are caused by a temporal discrepancy of the body clock relative to the surrounding environment and social network. The underlying mechanisms and general management are described. Both bright light and melatonin therapy have potential in the management of these disorders. Traditionally, bright light therapy has been used to alleviate the depression associated with seasonal affective disorder. Melatonin has received much ill-formed publicity, it being claimed that it is a panacea and an 'antiageing' treatment. Both of these treatment approaches are reviewed.
Walking on potential energy surfaces (1983)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTWalking on potential energy surfacesJack Simons, Poul Joergensen, Hugh Taylor, and Judy OzmentCite this: J. Phys. Chem. 1983, 87, 15, 2745–2753Publication Date (Print):July 1, 1983Publication History Published online1 May 2002Published inissue 1 July 1983https://pubs.acs.org/doi/10.1021/j100238a013https://doi.org/10.1021/j100238a013research-articleACS PublicationsRequest reuse permissionsArticle Views1564Altmetric-Citations394LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
A Comparative Study of Topical vs Retrobulbar Anesthesia in Complicated Cataract Surgery (2000)

Surgery-related complications and patient discomfort were similar for the 2 methods of anesthesia. Topical anesthesia is justified as a means of improving safety without causing discomfort to the patient even in complicated cases of cataract surgery. Arch Ophthalmol. 2000;118:1037-1043
Role of Autoantibodies in the Diagnosis of Connective-Tissue Disease ILD (CTD-ILD) and Interstitial Pneumonia with Autoimmune Features (IPAF) (2017)

The diagnosis of interstitial lung disease (ILD) requires meticulous evaluation for an underlying connective tissue disease (CTD), with major implications for prognosis and management. CTD associated ILD (CTD-ILD) occurs most commonly in the context of an established CTD, but can be the first and/or only manifestation of an occult CTD or occur in patients who have features suggestive of an autoimmune process, but not meeting diagnostic criteria for a defined CTD-recently defined as "interstitial pneumonia with autoimmune features" (IPAF). The detection of specific autoantibodies serves a critical role in the diagnosis of CTD-ILD, but there remains a lack of data to guide clinical practice including which autoantibodies should be tested on initial assessment and when or in whom serial testing should be performed. The implications of detecting autoantibodies in patients with IPAF on disease behaviour and management remain unknown. The evaluation of CTD-ILD is challenging due to the heterogeneity of presentations and types of CTD and ILD that may be encountered, and thus it is imperative that immunologic tests are interpreted in conjunction with a detailed rheumatologic history and examination and multidisciplinary collaboration between respiratory physicians, rheumatologists, immunologists, radiologists and pathologists.
The Use of Fibrin Glue in the Correction of Pollybeak Deformity (2003)

Fibrin glue is an excellent adjunct to rhinoplasty procedures because it successfully eliminates the dead space that can cause soft tissue pollybeak deformity.
One-step synthesis of α,β-unsaturated arylsulfones by a novel multicomponent reaction of aromatic aldehydes, chloroacetonitrile, benzenesulfinic acid sodium salt (2012)

为合成的一个新、绿的方法，不饱和的 arylsulfones 通过芳香的醛的冷凝作用被完成了， chloroacetonitrile，面对 1-butyl-3-methyl imidazolium 氢氧化物咸的 benzenesulfinic 酸钠([bmim ] 哦) 在在倒流下面的 EtOH。离子的液体为随后的反应被恢复并且再循环。协议是无毒的、容易的病情的检查和好收益的这的优点。
Synthesis and Biological Evaluation of Novel Epibatidine Analogues (2003)

In an effect to develop for more selective neuronal nicotinic acetylcholine receptor analgesics that have less toxicity and adverse side effects relative to epibatidine, three new classes of epibatidine analogues were synthesized and evaluated in vitro as potential potent selective nAChR ligands. Specifically, three analogues of epibatidine were synthesized to explore the structure-activity relationships of epibatidine relative to neuromuscular blocking activity as well as nAChRs. Both quaternary epibatidine analogues 2 and bis-epibatidine derivative 3 exhibited high binding affinity relative to nicotine. In addition, a new series of 2-(hydroxyalkylpyridyl)-7-azabicyclo[2.2.1]heptane derivatives were synthesized and evaluated as potential ligands for nicotinic acetylcholine receptors. Moreover, two rigid 2-acetoxy-7-azabicyclo[2.2.1]heptane analogues have been prepared to study the binding conformation of acetylcholine at the active sites of the nicotinic acetylcholine receptors.
Near Shannon limit quasi-cyclic low-density parity-check codes (2004)

The paper presents two classes of quasi-cyclic low-density parity-check (LDPC) codes which perform close to the Shannon limit. The construction of these codes is based on decomposition of circulant matrices constructed from finite geometries.
The constituent object parser: syntactic structure matching for information retrieval (1989)

article The constituent object parser: syntactic structure matching for information retrieval Share on Authors: D. P. Metzler Department of Information Science, University of Pittsburgh Department of Information Science, University of PittsburghView Profile , S. W. Haas Department of Information Science, University of Pittsburgh Department of Information Science, University of PittsburghView Profile Authors Info & Claims ACM SIGIR ForumVolume 23Issue SIJune 1989 pp 117–126https://doi.org/10.1145/75335.75348Online:01 May 1989Publication History 6citation327DownloadsMetricsTotal Citations6Total Downloads327Last 12 Months1Last 6 weeks0 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteGet Access
Reducing therapist contact in cognitive behaviour therapy for panic disorder and agoraphobia in primary care: global measures of outcome in a randomised controlled trial. (2000)

The standard therapist contact group showed the greatest treatment efficacy in the present study. As it was of notably shorter duration than many other current formulations of CBT, it represents a useful and efficient treatment for panic disorder and agoraphobia in primary care.
Redneck Redux (1991)

News| November 01 1991 Redneck Redux Grant H. Kester Grant H. Kester Search for other works by this author on: This Site PubMed Google Scholar Afterimage (1991) 19 (4): 2. https://doi.org/10.1525/aft.1991.19.4.2 Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter LinkedIn Tools Icon Tools Get Permissions Cite Icon Cite Search Site Citation Grant H. Kester; Redneck Redux. Afterimage 1 November 1991; 19 (4): 2. doi: https://doi.org/10.1525/aft.1991.19.4.2 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAfterimage Search This content is only available via PDF. © 1991 by The Regents of the University of California1991 Article PDF first page preview Close Modal You do not currently have access to this content.
Cellulose aluminium oxide coated with organofunctional groups containing nitrogen donor atoms (2000)

A composite of cellulose and aluminium oxide, cel/Al2O3, was prepared and further modified with organofunctional groups by reacting with the coupling reagent (C2H5O)3SiL, where L represents –(CH2)3NH2, –(CH2)3NH(CH2)2NH2, –(CH2)3NH(CH2)2NH(CH2)2NH2 or –(CH2)3N(C3H3)N [–N(C3H3)N = imidazolyl radical], abbreviated to ap, enp, dienp and imp, respectively. The experimental preparation procedures were very reproducible and resulted in the following values for the amount of organofunctional groups grafted on cel/Al2O3 (average values in mmol g−1): cel/Al2O3/Si(ap) = 0.35; cel/Al2O3/Si(enp) = 0.30; cel/Al2O3/Si(dienp) = 0.25 and cel/Al2O3/Si(imp) = 1.0. The 27Al MAS NMR spectra, which show an intensification of the area under the peak at 62 ppm due to Al in a tetrahedral environment, and the increase of the Al/C atomic ratios (determined from X-ray photoelectron spectra) after reaction with the coupling reagents indicate that Al atoms have migrated to the surface. This indicates that (C2H5O)3SiL is adsorbed on the matrix surface and reacts with the AlOH groups forming Al–O–Si bonds. The adsorption isotherms from ethanol solutions of FeCl3, CuCl2 and ZnCl2 were obtained at 298 K. The average stability constants were determined for each metal halide and the results indicated that the constants for the bi- and tridentate ligands, enp and dienp, are slightly higher than those for ap and imp, both monodentate ligands.
Sensorless active yaw control for wind turbines (2002)

An active yaw control scheme for a horizontal axis wind turbine is proposed. The control strategy is based on measurement of the generated output power, without any wind intensity and/or wind direction sensors. Special attention is given to some control parameters to make the yaw driver less sensitive to wind turbulence. Results obtained in the laboratory implementation are presented and discussed in this paper.
Operating lines in cascade separation of binary mixtures (1965)

Abstract The general case of cascade operation is treated without any restriction on the value of the separation factor. Equilibrium curves are briefly discussed. These are generally a function of the cut. The equations of operating lines for both of enriching and stripping sections are derived for the general case by appropriate material balances. Also, three specific applications are presented in detail, by showing graphical constructions and discussing characteristic features for each case.
Defining High Conflict (2010)

The term high conflict is used regularly across various literatures; such as divorce, family court, and psychotherapy; to describe relationships that are mired in conflict. Despite its widespread use, the term has not been precisely defined in a clinically meaningful way. This article offers a definition of high conflict based on a synthesis of previous literatures related to high conflict, observations of court personnel, and the authors’ own clinical experiences working with this population. A case study illustrates the pervasive negative exchanges and hostile insecure emotional environment that characterize these couples. The implications of this definition for clinical practice are also discussed.
Method for the Determination of Vitamin K Homologues in Human Plasma Using High-Performance Liquid Chromatography-Tandem Mass Spectrometry (2004)

We report here the development of a precise and sensitive method for the determination of vitamin K homologues including phylloquinone (PK), menaquinone-4 (MK-4), and menaquinone-7 (MK-7) in human plasma using HPLC-tandem mass-mass spectrometry with atmospheric pressure chemical ionization (LC-APCI-MS/MS). The method involves the use of stable isotope (18)O-labeled internal standard compounds, which were synthesized in our laboratory, and the selection of a precursor and product ion with a MS/MS multiple reaction monitoring method. The average intraassay and interassay variation values for PK, MK-4, and MK-7 were <10%. Average spiked recoveries from authentic compounds added to normal human plasma samples for PK, MK-4, and MK-7 were 98-102%. Mean plasma concentrations of PK, MK-4, and MK-7 from healthy subjects (n = 20) were 1.22 +/-0.57, 0.39 +/- 0.46, and 6.37 +/- 7.45 ng/mL, respectively. We conclude that this novel LC-APCI-MS/MS method should be useful for the evaluation of vitamin K status in postmenopausal women and elderly subjects and provides useful information for the treatment and prevention of osteoporosis with vitamin K.
Cross-Linked Hyaluronic Acid Films to Reduce Intra-Abdominal Postsurgical Adhesions in an Experimental Model (2009)

Placement of HA films between injured tissues significantly decreases the severity of abdominal adhesions. Furthermore, the HA film's resistance to monocyte adhesion could be contributory to lowering in vivo adhesion scores.
Optical Properties of the Silver and Cuprous Halides (1963)

The exciton spectrum of AgI, CuI, CuBr, and CuCl is discussed and various peaks attributed to several coexisting crystal modifications. The shift of the peaks with alloy concentration in the pseudobinary systems formed with these compounds is reported and interpreted. The absorption and reflection spectra of these materials and their alloys for energies between the energy gap and 10 eV is reported and the structure attributed to transitions between regions of the valence band lying below the highest maximum and parts of the conduction band higher than the lowest minimum. These spectra are compared with the corresponding spectra of other zincblende- and wurtzite-like materials.
Transaminations catalysed by brain glutamate decarboxylase (1985)

In addition to normal decarboxylation of glutamate to 4-aminobutyrate, glutamate decarboxylase from pig brain was shown to catalyse decarboxylation-dependent transamination of L-glutamate and direct transamination of 4-aminobutyrate with pyridoxal 5'-phosphate to yield succinic semialdehyde and pyridoxamine 5'-phosphate in a 1:1 stoichiometric ratio. Both reactions result in conversion of holoenzyme into apoenzyme. With glutamate as substrate the rates of transamination differed markedly among the three forms of the enzyme (0.008, 0.012 and 0.029% of the rate of 4-aminobutyrate production by the alpha-, beta- and gamma-forms at pH 7.2) and accounted for the differences among the forms in rates of inactivation by glutamate and 4-aminobutyrate. Rates of transamination were maximal at about pH 8 and varied in parallel with the rate constants for inactivation from pH 6.5 to 8.0. Rates of transamination of glutamate and 4-aminobutyrate were similar, suggesting that the decarboxylation step is not entirely rate-limiting in the normal mechanism. The transamination was reversible, and apoenzyme could be reconstituted to holoenzyme by reverse transamination with succinic semialdehyde and pyridoxamine 5'-phosphate. As a major route of apoenzyme formation, the transamination reaction appears to be physiologically significant and could account for the high proportion of apoenzyme in brain.