gebhart/patrepeval huggingface dataset:
Effects of islet cell surface antibodies on isolated neonatal rat islets of Langerhans in vitro. (1986)

Islet cell surface antibodies (ICSA) were raised by immunization of rabbits with viable neonatal rat pancreatic islet cell suspensions. By absorption with liver powder and spleen cells unspecific cytotoxic components were removable from the sera. Cytotoxic effect of islet cell antiserum against islet cells was indicated by 51Cr-release. In dependence on serum concentration beta-cell damage induced by ICSA-positive serum was detectable by insulin leakage from neonatal rat islets of Langerhans. The immune cytolytic effect of rabbit anti-rat islet cell surface serum was accompanied by morphological alterations of the islet surface structure as revealed by scanning electron microscopy. Pretreatment of pancreatic islets with cytotoxic islet cell antiserum results in an increased insulin leakage even after the removal of the cytotoxic conditions suggesting the persistence of cell membrane lesions. Insulin secretion of islets of Langerhans first exposed to cytotoxic ICSA-positive serum is still stimulated by 15 mmol/1 glucose plus 0.1 mmol/1 3-isobutyl-1-methylxanthine (IBMX) but taking into account the increased insulin leakage the secretory capacity of these islets is significantly diminished.
Outpatient intravenous antibiotic therapy. (1989)

Outpatient intravenous antibiotic therapy is a cost-effective modality to shorten hospital stays and provide continued care to patients with infections. The recent availability of tamper-proof pumps that can deliver multiple antibiotics on independently timed regimens will further expand the use of home intravenous antibiotics. Problems with reimbursement remain, and new classes of oral antibiotics may provide alternatives to parenteral medications.
A Synthetic Diet for the Spruce Budworm, <i>Choristoneura fumiferana</i> (Clem.) (Lepidoptera: Tortricidae) (1965)

Abstract The spruce budworm, Choristoneura fumiferana (Clemens), was reared on a synthetic diet. Comparison of two successive laboratory generations reared on synthetic diet and on frozen balsam fir buds showed that diet-fed insects had a higher survival, developed faster, were heavier, mated more successfully, and were more fecund.
Isolation and characterization of lactic acid bacteria producing antimutagenic substance from Korean Kimchi (1999)

Various lactic acid bacteria were isolated from Korean Kimchi in order to study their antimutagenic substances. Ames test using Salmonella typhimurium TA98 and TA100 showed the strain KLAB21 to have the highest antimutagenic activity among the 230 isolated strains against MNNG (N-methyl-N'-nitro-N-nitrosoguanidine), NPD (4-nitro-O-phenylenediamine), NQO (4-nitrosoquinoline-1-oxide) and AFB1 (aflatoxin B1). The strain was identified as Lactobacillus plantarum based on its morphological, cultural and physiological characteristics. Antimutagenic activity of L. plantarum KLAB21 was found in culture supernatant suggesting the bacterium secrete antimutagenic substance in the media. No mutagenic activity was found in the culture supernatant. The isolated strain L. plantarum KLAB21 showed much higher antimutagenic activity than L. plantarum IAM1261 which is being used industrially for fermented milk production. The antimutagenic activity of L. plantarum KLAB21 was reconfirmed by the spore-rec assay using spores of Bacillus subtilis H17(Rec+) and M45(Rec-).
Effect of strategic deworming of village cattle in Uganda with moxidectin pour-on on faecal egg count and pasture larval counts : short communication (2004)

Strategic application of moxidectin pour-on (Cydectin) was evaluated in Uganda for its effect on pasture larval counts and gastrointestinal nematode faecal egg counts in village cattle kept under tethering (semi-intensive) grazing management. The strategic deworming schedule involved treating cattle twice at an interval of 2 months, at the end of the 1st wet season and during the 2nd wet season. Two groups of 30 cattle, each consisting of a treated and a control group, were examined for nematode infections every 4 weeks from June 1999 to January 2000. The treated group had significantly lower mean faecal egg counts than the untreated groups (t-value = 2.47, P < 0.05). Generally, the pasture larval counts on treated farms were lower than on untreated ones, but not significantly so (t-value = 2.22, P = 0.068). Pasture larval counts with different nematode species on treated farms were lower than on untreated ones, but the differences were not significant for Haemonchus spp. (t-value = 1.68, P = 0.145), Oesophagostomum spp. (t-value = 1.87, P = 0.111), Trichostrongylus spp. (t-value = 1.93, P = 0.102), Dictyocaulus spp. (t-value = -0.74, P = 0.485) and Cooperia spp. (t-value = -1.00, P = 0.356). Treated farms did, however, have significantly lower pasture larval counts of Bunostomum spp. (t-value = 4.64, P < 0.05). This study has revealed that the application of moxidectin pour-on on cattle has an effect on faecal egg count and pasture contamination under the tethering grazing system. Moxidectin pour-on and the strategic deworming schedule evaluated here could be used for the control of gastrointestinal nematode infections in cattle by small-scale farmers who practise tethering or semi-intensive grazing management in Uganda and other tropical countries, especially where there is a bimodal rainfall pattern.
Properties of the spectrin‐like structural element of smooth‐muscle α‐actinin (1991)

The fragment of smooth muscle alpha-actinin, comprising the four spectrin-like structural repeating units, has a high alpha-helix content, similar to that of spectrin, and a hydrodynamic frictional coefficient, indicative of an elongated, probably bent or kinked rod-like structure, as found for spectrin dimer and tetramer. The fragment exists in solution as an extremely stable dimer, which is dissociated only under denaturing conditions and is much more resistant to dissociation by urea than is the spectrin heterodimer. High-resolution proton magnetic resonance spectra reveal that a part of the polypeptide chain gives rise to sharp resonances; this is also true of spectrin and it implies that the individual structural repeating units contain segmentally mobile elements, which may be required to generate the elastic properties of the spectrin family of proteins. Again like spectrin, the alpha-actinin fragment contains multiple binding sites for long-chain fatty acids, as revealed by quenching of tryptophan fluorescence by 2-bromostearate (though not by 9(10)-bromostearate). The results point to extensive structural and functional similarities between the repeating units of all the proteins of the spectrin family.
In vitro and in vivo studies of ePTFE vascular grafts treated with P15 peptide (2005)

The purpose of this study is to evaluate the effectiveness of P15 cell-binding peptide treated ePTFE vascular grafts in vitro and in vivo. The P15 peptide was covalently immobilized onto ePTFE vascular grafts by an atmospheric plasma coating method. In vitro cell growth properties were studied using primary human umbilical vein endothelial cells (HUVECs) and primary human umbilical artery smooth muscle cells (HUASMCs). X-ray photoelectron spectroscopy and amino-acid analysis were used to analyze the surface characteristics of the peptide treated and untreated grafts. The cell growth study showed that the P15 peptide effectively promoted the adhesion and proliferation of endothelial cells. 700% more endothelial cells were proliferated on the P15-treated ePTFE grafts compared to the untreated ePTFE controls. In contrast, the P15 peptide was significantly less effective for promoting the adhesion and proliferation of smooth muscle cells than endothelial cells; only about 100% more smooth muscle cells proliferated on the P15-treated samples compared to the untreated control samples. The sheep model was used in the in vivo study. The amount of neointimal hyperplasia present at the arterial and venous sides of the anastomosis and the degree of endothelialization on the luminal surface of the grafts were assessed. Four P15-treated grafts and two control grafts were implanted as arteriovenous grafts between the femoral artery and vein or the carotid artery and jugular vein in two sheep (n = 6). The in vivo study showed that the thickness of the neointimal hyperplasia of untreated grafts was 3-times thicker than that of P15-treated grafts (P < 0.05) at the venous side of the anastomosis. P15-treated grafts also had a higher degree of endothelialization on the graft lumen.
A Sputtered Silicon Oxide Electrolyte for High-Performance Thin-Film Transistors (2017)

Low operating voltages have been long desired for thin-film transistors (TFTs). However, it is still challenging to realise 1-V operation by using conventional dielectrics due to their low gate capacitances and low breakdown voltages. Recently, electric double layers (EDLs) have been regarded as a promising candidate for low-power electronics due to their high capacitance. In this work, we present the first sputtered SiO<sub>2</sub> solid-state electrolyte. In order to demonstrate EDL behaviour, a sputtered 200 nm-thick SiO<sub>2</sub> electrolyte was incorporated into InGaZnO TFTs as the gate dielectric. The devices exhibited an operating voltage of 1 V, a threshold voltage of 0.06 V, a subthreshold swing of 83 mV dec<sup>-1</sup> and an on/off ratio higher than 10<sup>5</sup>. The specific capacitance was 0.45 µF cm<sup>-2</sup> at 20 Hz, which is around 26 times higher than the value obtained from thermally oxidised SiO<sub>2</sub> films with the same thickness. Analysis of the microstructure and mass density of the sputtered SiO<sub>2</sub> films under different deposition conditions indicates that such high capacitance might be attributed to mobile protons donated by atmospheric water. The InGaZnO TFTs with the optimised SiO<sub>2</sub> electrolyte also showed good air stability. This work provides a new pathway to the realisation of high-yield low-power electronics.
High capacity digital network management and control (2002)

Modern wideband and broadband digital cross-connect systems are being increasingly deployed in fiber networks in the Bell Operating Companies (BOCs). A network controller maximizes the effectiveness of these elements in automating the management and control high capacity digital networks, and the provisioning and service restoration of DS1 and DS3 facilities. Strategies used in providing the above capabilities in a recently deployed network, and associated architectures and interfaces are discussed. The first customer application of AT&T's DACScan-2000 controller is used to illustrate how these strategies are realized in the BOC environment.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Physical and chemical cell disruption for the recovery of intracellular proteins. (1991)

There are many ways to disrupt microorganisms and plant and animal tissue. Selecting the best cell disruption method depends on the factors listed in Table 6. The kind or type of cells is an important consideration. For example, some disruption methods which work well for animal tissue do not work at all for microorganisms. A guideline for the suitabiity of a given disruption method for some cell types is given in Table 7. The ratings in this table are not incontestable and, as mentioned earlier, combinations of methods can sometimes produce satisfactory results whereas one method alone fails. The disruptibility of cells can be influenced by their growth and storage history. For microorganisms, cells in log phase growth tend to produce thinner cell walls which are more easy to disrupt. This and other conditions which can influence microbial cell disruptiability are listed in Table 8. The cell disruption method selected will depend on its capability to process samples of a certain size or to be able to process multiple samples in a reasonable period of time. Other considerations are the availability, cost, and general utility of the disruption equipment. Thus, in a research environment the purchase of an expensive cell disrupter which processes a wide variety of cell types may be more easy to justify than a specialized disrupter. And if the long-term goal is to scale up, the choice of disruption methods narrow considerably. Indeed, several of the most successful laboratory cell disruption methods have no possibility of being scaled up. Despite possible scale-up difficulties, in the case of many bioactive recombinant products expressed at high levels in microorganisms, this concern may be irrelevant. Few of these products are likely to be manufactured in really large amounts and current laboratory scale or pilot plant scale production equipment may be entirely adequate. For instance, active human TNF (tissue necrosis factor) can be expressed in Pichia pastoris yeast at levels of 100 g/kg of yeast (dry weight). At this level of expression, only a few kilograms of r-DNA yeast needs be disrupted to meet the worldwide demand for this research material. Finally, the operating and energy requirements which affect the economics of the disruption process (batch versus continuous, disruption yield, cell fragment size, effect of added enzymes on downstream separation, etc.) are important considerations in the selection of production equipment.
Radiohalogen incorporation into organic systems (2002)

Abstract This Review reports the more recent applications of radiohalogen labelling in organic compounds. Modern synthetic methods place more emphasis upon substitution at specific sites. Electrophilic substitution, especially at aromatic carbon atoms, involves displacement of halogen or of metals rather than the earlier popular halogen‐deprotiation processes. Nucleophilic displacement, at either aliphatic or aromatic sites, has also become widespread since it may be made more selective by the inclusion of appropriate activating groups or suitable displaced groups. Microwave and thermally induced methods are both reported with a critical assessment of the value of each process. Copyright © 2002 John Wiley & Sons, Ltd.
The effectiveness of mézières therapy in the ucam’s athletes with low back pain (2019)

Se pretende verificar la efectividad del tratamiento postural del Método Mézières (MM) en diferentes atletas con dolor lumbar leve o moderado. DISEŇO: Ensayo aleatorio controlado, paralelo y doble ciego que comparó la pre y post intervención de 24 semanas en 2 grupos: experimental y control activo. AJUSTE: Campo de entrenamiento. PARTICIPANTES: Ciento treinta y nueve atletas en total, con dolor de espalda (LBP) participaron en el estudio. Concretamente, la muestra utilizada estaba formada por gimnastas de la gimnasia rítmica nacional en Murcia; Jugadores del equipo de baloncesto UCAM Murcia CB / EBA, y del equipo UCAM Murcia Futbol Club. INTERVENCIÓN: En consecuencia, se utilizaron tres posturas básicas, aquellas que actuaron preferiblemente en la cadena posterior de una manera más global: posición supina con las piernas a 90 °, en posición sentada y en posición vertical con una flexión de 90 °. MEDIDAS DE LOS RESULTADOS: Se utilizaron; la escala analógica visual del dolor (VAS), la prueba de flexibilidad Sit and Reach, la aplicación de Android Runtastic Podómetro, el cuestionario de Roland-Morris (CRM) que mide la discapacidad física de los atletas y el cuestionario de estado de salud (SF-12). RESULTADOS: Al observar el Grupo de Control (CG) y el Grupo Experimental (EG), se evidenció que la escala de evaluación del dolor VAS en las pruebas previas (T0-T1) tuvo un valor significativo (F = 32.7; p˂0.05; η2 = 0.19) en el análisis entre grupos. Y el tamaño del efecto entre los grupos fue alto durante las 50 sesiones de tratamiento (d˃0.8). Para la prueba de flexibilidad Sit and Reach se pudo observar un cambio significativo entre el análisis de grupos (F = 27.7; p˂0.05; η2 = 0.16). Además, por lo que respecta al tamaño del efecto entre grupos, se confirmó que es alto durante el período de intervención (d˃0.8). Para el rendimiento del podómetro Runtastic, en el análisis entre grupos, se observó un efecto significativo (F = 399.1; p˂0.05; η2 = 0.74) y un alto tamaño del efecto durante toda la fase de tratamiento (d˃0.8). El estado de incapacitación (CRM) se observó en la diferencia entre grupos y se anotó una significación en el propio análisis (F = 44.2; p˂0.05; η2 = 0.24). Concretamente, el tamaño del efecto fue alto durante las 24 semanas de tratamiento (d˃0.8). Y las diferencias entre los grupos del estado de salud (SF12) y el tamaño del efecto analizado para las dos subescalas (PCS y MCS) también fue significativo (p˂0.05; d˃0.8). CONCLUSIÓN: MM puede aplicarse en protocolos convencionales establecidos para aliviar el dolor y la funcionalidad, al mejorar la calidad de vida del deportista junto con su estado físico y emocional.
La notificación a las personas jurídicas a través de la Sede Judicial Electrónica (2018)

Con la interpretacion integradora de la normativa vigente no cabe duda no solo de la validez, sino tambien de la obligacion de realizar todas las comunicaciones con las personas juridicas de los actos procesales electronicamente, a traves de la direccion electronica habilitada, siendo plenamente aplicable el articulo 162 LEC en cuanto a su eficacia y consecuencias. No obstante, a la vista de las posturas discordantes, todas juridicamente defendibles, seria de agradecer una aclaracion via pleno no jurisdiccional por parte del Tribunal Supremo en evitacion de situaciones que pudieran determinar la nulidad de lo actuado con la perdida que conlleva, tanto para el justiciable como para las oficinas judiciales.
A Collaborative and Content Based Event Recommendation System Integrated with Data Collection Scrapers and Services at a Social Networking Site (2009)

There are many activities that people prefer/opt out attending and these events are announced for attracting people. An intelligent recommendation system can be used in a social networking site in order to recommend people according to content and collaboration assessment. This study is an effort to recommend events to users within a social networking site. It can be any networking environment. We have used social environment that has been designed as a facebook application. Our application has also been integrated with several web sites. System collects event data from several related web sites either by using web services or web scraping. It also permits users rating events they have attended or planned. Given the social network between people, system tries to recommend upcoming events to users. For this purpose a combination of content based and collaborative filtering has been used. We have also taken geographical location info and social concept of an event.
HEREDITARY NEUROPATHY WITH LIABILITY TO PRESSURE PALSIES. ELECTROPHYSIOLOGICAL AND HISTOPATHOLOGICAL ASPECTS (1972)

Journal Article HEREDITARY NEUROPATHY WITH LIABILITY TO PRESSURE PALSIES. ELECTROPHYSIOLOGICAL AND HISTOPATHOLOGICAL ASPECTS Get access F. BEHSE, F. BEHSE Institute of Neurophysiology, the Laboratory of Clinical Neurophysiology, Rigshospital, and the Physical Laboratory II, University of CopenhagenDenmark Search for other works by this author on: Oxford Academic PubMed Google Scholar F. BUCHTHAL, F. BUCHTHAL Institute of Neurophysiology, the Laboratory of Clinical Neurophysiology, Rigshospital, and the Physical Laboratory II, University of CopenhagenDenmark Search for other works by this author on: Oxford Academic PubMed Google Scholar F. CARLSEN, F. CARLSEN Institute of Neurophysiology, the Laboratory of Clinical Neurophysiology, Rigshospital, and the Physical Laboratory II, University of CopenhagenDenmark Search for other works by this author on: Oxford Academic PubMed Google Scholar G. G. KNAPPEIS G. G. KNAPPEIS Institute of Neurophysiology, the Laboratory of Clinical Neurophysiology, Rigshospital, and the Physical Laboratory II, University of CopenhagenDenmark Search for other works by this author on: Oxford Academic PubMed Google Scholar Brain, Volume 95, Issue 4, 1972, Pages 777–794, https://doi.org/10.1093/brain/95.4.777 Published: 01 January 1972 Article history Published: 01 January 1972 Received: 09 March 1972
Josephson-Junction Amplifier (1971)

Positive feedback has been used within a double-Josephson-junction quantum interferometer to achieve a current amplification which can be adjusted from outside the cryostat over the range 1–100. The interferometer may be regarded as a three-terminal amplifying device.
Rate control for scalable video model (2005)

Scalable video coding (SVC) has become more and more important with the enrichment of multimedia data and the diversification of network and terminal devices. In current MPEG SVC activities, a scalable extension of H.264/AVC, called scalable video model (SVM), is proposed by HHI and has shown further coding efficiency improvement and scalability functionality. However, the SVM model doesn't provide an efficient rate control scheme now, and rate control is achieved through a full search for selecting a suitable quantization parameter (QP). That is very inefficient and much time-consuming. In this paper, an efficient rate control scheme is proposed for the SVM, which is derived from the state-of-the-art hybrid rate control schemes of JVT with some considerations for scalable video coding. In the proposed rate control scheme, the rate distortion optimization (RDO) involved in the step of encoding temporal subband pictures is only implemented on the low-pass subband pictures, and rate control is independently applied to each spatial layer. For each spatial layer, the rate control is implemented at GOP, picture and basic unit levels. Furthermore, for the temporal subband pictures obtained from the motion compensation temporal filtering (MCTF), the target bit allocation and quantization parameter selection inside a GOP could make full use of the hierarchical relations inherent from the MCTF. The proposed rate control scheme has been implemented into SVM3.0 and experiment results show that the proposed algorithm can achieve the target bit rate with little bit rate fluctuation and keep fine image quality at the same time, but the computation complexity is reduced heavily.
Metadata and the Web (2004)

The rapid increase in the number and variety of resources on the World Wide Web has made the problem of resource description and discovery central to discussions about the efficiency and evolution of this medium. The inappropriateness of traditional schemas of resource description for web resources has encouraged significant activities recently on defining web-compatible schemas named "metadata". While conceptually old for library and information professionals, metadata has taken more significant and paramount role than ever before and is considered as the golden key for the next evolution of the web in the form of semantic web. This article is intended to be a brief introduction to metadata and tries to present its overview in the web.