gebhart/patrepeval huggingface dataset:
Giant and isotropic low temperature magnetocaloric effect in magnetic semiconductor EuSe (2013)

We present the giant and isotropic magnetocaloric effect (MCE) in antiferromagnetic semiconductor EuSe. Near the transition temperature TN = 4.6 K, the maximum value of the magnetic entropy change (−ΔSmmax) and the relative cooling power of EuSe for a field change of 5 T are evaluated to be 37.5 J kg−1 K−1 and 580 J kg−1, respectively, based on the magnetization and specific heat data. The −ΔSmmax value of EuSe obtained in this work is the largest among the low temperature (&lt;20 K) magnetic refrigerant materials reported so far, which is even larger than that of the best known room temperature giant MEC materials.
Lower risk of severe hypoglycaemia with insulin glargine 300 U/ <scp>mL</scp> versus glargine 100 U/ <scp>mL</scp> in participants with type 1 diabetes: A <scp>meta‐analysis</scp> of <scp>6‐month</scp> phase 3 clinical trials (2020)

Severe hypoglycaemia (SH) remains a challenge to people with type 1 diabetes (T1DM), and new-generation basal insulins may improve patient outcomes. This post hoc meta-analysis explored the risk of SH with insulin glargine 300 U/mL (Gla-300) versus glargine 100 U/mL (Gla-100) in a pooled population with T1DM from three randomized, multicentre, 6-month similarly designed phase 3 trials: EDITION 4, EDITION JP 1 and EDITION JUNIOR. Endpoints included incidence and time to first occurrence of SH. Among 629 and 626 participants randomized to Gla-300 and Gla-100, respectively, glycated haemoglobin reductions were similar. Fewer participants experienced ≥1 SH event with Gla-300 (6.2%) than with Gla-100 (9.3%). From baseline to month 6, the risk of a first SH event was lower with Gla-300: hazard ratio 0.65 [95% confidence interval (CI) 0.44-0.98; stratified log-rank test P = 0.038]. SH event rates were numerically lower with Gla-300 versus Gla-100 from baseline to month 6 [relative risk (RR) 0.80 (95% CI 0.49-1.29); P = 0.356] and baseline to week 8 [RR 0.73 (95% CI 0.37-1.44); P = 0.369]. Thus, Gla-300 demonstrated similar glycaemic control with lower risk of SH versus Gla-100, particularly during the titration period.
Nonenzymatic Modification of Ubiquitin under High-Pressure and -Temperature Treatment: Mass Spectrometric Studies (2014)

The effect of high-pressure and/or high-temperature on the glycation of a model protein (ubiquitin) was investigated by mass spectrometry. This paper reports the impact of high pressure (up to 1200 MPa) on the modification of a ubiquitin using ESI-MS measurements. The application of glucose labeled with stable isotope allows a quantitative assessment of modification under the conditions of high-pressure (HPG) and high-temperature (HTG) glycation. A higher degree of modification was observed for the sample heated at 80 °C for 25 min under atmospheric pressure than for sample treated under high pressure. In samples treated at pressure below 400 MPa an insignificant increase of glycation level was observed, whereas high pressure (>600 MPa) has only a minor effect on the number of hexose moieties (Fru) attached to the lysine residue side chain.
Indirect foraminal decompression after lateral transpsoas interbody fusion (2012)

Average foraminal area increased approximately 35% after cage placement without variation based on cage position. While ODI and SF-12 scores increased significantly, there was no significant association with cage position or foraminal area change, likely attributable to the multifactorial nature of preoperative pain.
Radiation-Associated Sarcoma? (2011)

To the Editor: I read the recent article by Schmitt et al1 titled “Radiation-Induced Sarcoma in a Large Vestibular Schwannoma Following Stereotactic Radiosurgery: Case Report.” As the authors state, “It is, therefore, possible that this tumor represented a low-grade sarcoma that initially responded favorably to the [stereotactic radiosurgery] treatment but then further dedifferentiated and progressed more aggressively. Without pretreatment tissue diagnosis there is no way to resolve this dilemma definitively.” I have several comments on this report. First, because the original pathology was not known, this does not fulfill the Cahan criterion of a change in histology. Second, the tumor approximately tripled in volume between the June 2000 and May 2001 scans before radiosurgery (Figures 1 and 2). This growth rate is not typical of a vestibular schwannoma. Third, the degree of postirradiation edema at 7 months is atypical. I think that the title could have been better stated as “radiation-associated” sarcoma, not “radiation-induced.” The issue of causation is important. Indeed, this tumor may have been an unrecognized sarcoma at presentation. Loeffler et al2 wrote an article on this topic 8 years ago. Douglas Kondziolka Pittsburgh, Pennsylvania
Baculovirus-mediated Gene Transfer: An Evolving New Concept (2000)

I. INTRODUCTION The great potential of gene therapy has recently been supported by successful treatments of immune deficiency and cancer patients (1,2). However, much remains to be solved before gene therapy becomes a standard procedure. One major obstacle is the low efficiency of gene transfer (3); thus, further development of vectors is necessary. In this context, baculoviruses have raised increasing interest because they have a long history as safe and efficient gene delivery tools in insect cells (4), and the long-lived dogma of incompability with mammalian cells has recently been revised (5-7).
Intra‐tumoral administration of naked plasmid DNA encoding mouse endostatin inhibits renal carcinoma growth (2001)

Endostatin is a C-terminal fragment of collagen XVIII and has potent anti-angiogenic and anti-tumor activity. Mouse endostatin-coding sequences were obtained using PCR and linked to the signal sequence of influenzavirus hemagglutinin. The signal-sequence endostatin fragment was subcloned into plasmid vectors under the transcriptional control of cytomegalovirus promoter. Murine renal carcinoma (Renca) cells transfected with endostatin-coding plasmid are shown to secrete full-length endostatin. Endostatin-secreting Renca cells demonstrate slower growth in vivo compared to empty vector–transfected cells, but their in vitro growth is unaffected. Anti-angiogenic activity of secreted endostatin was confirmed in a Matrigel angiogenesis assay in vivo. We report growth inhibition of Renca tumors resulting from intra-tumoral delivery of plasmid vector encoding secretable endostatin. Elevated local concentrations of endostatin resulted from multiple intra-tumoral injections of endotoxin-purified plasmid DNA. Local endostatin levels were high enough to obtain growth arrest of Renca tumors. © 2001 Wiley-Liss, Inc.
Synthesis, structure and magnetic properties of the one-dimensional chain compound {K[Fe(1,3,5-triazine-2,4,6-tricarboxylate)(H2O)2]·2H2O}∞ (2002)

The one-dimensional chain compound {[Fe(1,3,5-triazine-2,4,6-tricarboxylate)(H2O)2]}n−n was obtained from a reaction of 1,3,5-triazine-2,4,6-tricarboxylate with Fe(II) in water at room temperature. The high-spin Fe(II) centers adopt a pentagonal bipyramid geometry with unusual ligand binding modes. Magnetic measurements revealed weak magnetic interactions between paramagnetic centers; these were modeled with both axial and rhombic distortions.
Cationic Zirconocene Mediated Cascade Synthesis of Tetrahydrofurans (2005)

Tetrahydrofurans and tetrahydropyrans are common structural features of numerous natural products, most notably the marine toxins and the polyether antibiotics, such brevetoxin and monensin. Despite the structural complexity of these two classes of compounds, a similarity arises when comparing the structural cores. The framework of all polyether antibiotics contains 2,5-disubstituted tetrahydrofurans, substituted tetrahydropyrans and spiroketal systems. A characteristic feature in the core of marine toxins is a trans-fused polycyclic ether moiety. Because of these similarities, it is believed that polycyclic ether compounds have a similar biogenetic origin, and many groups have postulated that Nature synthesizes these compounds via a polyene→polyepoxide→polyether pathway. Based on previous Wipf group methodology, enantiomerically pure diepoxide substrates with electronically differently ester terminating groups were subjected to 10 mol% Cp₂ZrCl₂ and 20 mol% AgClO₄. It was found that the 2-furyl and 2-benzofuryl ester moieties furnished the best yields and diastereoselectivities of the desired highly functionalized tetrahydrofurans.
Optical amplification of vacuum ultraviolet argon excimer produced by a high-intensity laser (2007)

We report the Ar <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> amplification with a gain-length product of 6 pumped by a high-intensity laser and the generation of subpicosecond seed pulses at 126 nm using harmonic radiation of an infrared Ti:sapphire laser.
The magnetic aftereffect in CoCr films: A model (1990)

We have previously reported experimental studies of the magnetic aftereffect in CoCr films. In that work data were compared to phenomenological models, and it was recognized that the decay of the magnetization was driven by the demagnetizing field. The difficulty of incorporating such fields into phenomenological models, which rely on a broad distribution of relaxation times or activation energies to account for the quasilogarithmic decays, motivated the present study. Here we present a simple alternate model which does not assume a distribution of energies. Instead, we focus on the time dependence of the local magnetic field h which drives the magnetization. We approximate h by the average internal field Hi =Ha−4πM, where Ha is the applied field, M is the magnetization averaged over regions large compared to domains, and 4π is the demagnetizing factor appropriate for a planar geometry. The magnetization is found to relax quasilogarithmically with time in this model. We have also made a more detailed comparison with experimental results. We conclude that this simple model is more transparent to the essential physics of the problem than previously used models, and may be useful in analyzing decays in other materials.
Conductivity assessment of conductive polymer bonding for flip chip applications (2002)

Numerous experimental studies of electrically conductive polymers have shown that bonding systems between flip chip and substrate with conductive polymers have a certain amount of contact resistance between contact pad and conductive polymer and among the fillers, in addition to the bulk resistance of the fillers themselves. The contact resistance of a conductive polymer bonding system and its variation in a life cycle are obviously two important parameters that impact the electrical behavior of electrical components and devices, if flip chip bonding is involved in their packaging. There are two kinds of conductive polymers, isotropically conductive polymer and anisotropically conductive polymer, which have been intensively studied for application to flip chip packaging. Conductive polymers generally consist of conductive filler and adhesive polymer matrix. The electrical conductivity depends not only on filler material, filler ratio, and operating environment, but also on filler packing structure, voltage drop across the contact spot and mechanical stress due to the mismatch of coefficients of thermal expansion, which results in deformation of the chip and substrate. In this paper, we conducted an analysis, based on fundamental electrical contact physics, material kinetics and particle packing structure, to deepen our understanding of the correlation between the conductivity of the polymer bonding system and key variables such as filler packing configuration, stress, voltage drop and operating environment.
Application-tailored database systems: a case of aspects in an embedded database (2004)

Current techniques used to design and implement database systems do not provide support for efficient implementation of crosscutting concerns in the database software, e.g., failure detection, database policies such as concurrency control and scheduling, and synchronization. Aspect-oriented software development (AOSD) is a new technique that provides an efficient way of modularizing crosscutting concerns in software systems. In This work we evaluate the effectiveness of applying AOSD to database systems thereby paving way for successful application of aspect languages to the database domain. Our focus is on embedded database systems, as a representative for a class of database systems. We show, by analyzing and re-engineering one commercial well-known embedded database system (Berkeley database), that aspect-orientation has promise, especially in enabling development of tailorable, maintainable, and evolvable database systems.
Characterization of Surface Structure of Silica Thin Films by Auger Parameter (2001)

Abstract Si Auger parameter of silica films obtained under different hydrolysis conditions was calculated in order to determine SiOH concentration. It was found that the Auger parameter increased with increasing silicate molecular. Silica films with a large Auger parameter were observed by transmission electron microscope (TEM) to consists of a large diameter particle than films with a small Auger parameter. Increased silica particle diameter demonstrates that the condensation reaction proceeds to an extent that the concentration of OH groups has decreased. It has been concluded that silica film surfaces with a large Auger parameter had few OH groups per Si atom.
On the dynamics of manipulators in space using the virtual manipulator approach (2005)

Robotic manipulators carried by future spacecraft are expected to perform important tasks in space, like servicing satellites. Such applications will encounter problems due to the dynamic coupling between the manipulator and the spacecraft. A Virtual Manipulator (VM) concept has been developed recently for the modelling of manipulators working in space. This paper shows that the VM facilitates planning and control of the motions of manipulators mounted on spacecraft, that minimizes the degrading consequences of manipulator/vehicle dynamic interactions. The VM is a new theoretical approach for the design and development of future space manipulator systems.
Safety and efficacy of abciximab combined with dalteparin in treatment of acute coronary syndromes (2002)

Treatment with abciximab, aspirin and s.c. dalteparin is associated with a low risk of major side effects and is as safe as the combination of abciximab and UFH. Without early coronary intervention there is no indication for abciximab treatment.
Transportation, Launch, and Self-Upend Analysis of the Kilauea Jacket Using Proven Analytical Techniques (1990)

ABSTRACT The self-upending, light-weight Kilauea jacket was designed with a minimum amount of flooding and venting equipment. The installation procedure was sensitive to changes in the jacket's weight and buoyancy properties. As a result, this jacket was subjected to extensive installation engineering and careful weight monitoring. This paper describes the methodology and results of the transportation, launch, self-upend, flotation, set-down and on bottom stability analyses of the Kilauea jacket. All hydrodynamic and friction coefficients and weight margins used are based on experience gained from past projects. Controlled ballasting was used to set the jacket down on the seabed and to obtain initial leveling and on-bottom stability. INSTALLATION PHILOSOPHY Installation Overview In the final design stage, it was envisioned that the Kilauea jacket would be installed based on the following general procedures:Load out the jacket from McDermott's fabrication yard on to the launch barge Intermac 650 (I-650) with the barge freely floating at an approximate draft of 30 feet. At this draft, the barge launch ways are level with the fabrication skid ways.After load out, reduce the barge draft to the design Gulf tow draft (24 feet) and install transverse and longitudinal sea fastenings and prepare the jacket and the barge for tow.Reduce the barge draft to 14 feet for river tow and tow the jacket using three river tugs to the Eugene Island sea buoy.Based on good weather forecast, replace the three river tugs with three ocean going tugs and start the Gulf tow while continuing to ballast the barge down to arrive at the Gulf tow draft.Prior to the arrival at the launch site, and on confirmation of good weather forecast for launch, barge ballasting is continued to arrive at the pre-launch configuration.Prepare to launch the jacket against the current and facing the derrick barge. Two tugs and two head lines from the derrick barge are connected to the top four corners of the jacket (see Figure 1).Once all sea fastenings have been cut, and the I-650 is in the pre-launch draft and trim condition, the jacket is jacked until it starts sliding by itself and launch begins. After launch, the jacket self-upends itself and is then pulled in towards the derrick barge using the two headlines.Once the jacket is at the stern of the derrick barge, the derrick barge crane is attached and lifts the jacket about 10 feet to gain more positive control of the jacket. This is followed by lowering of the jacket to the seabed using a combination of hooklC1ad and controlled ballasting of the jacket's compartments. Further ballasting is then used to level the jacket to within acceptable limits and to achieve the desired on-bottom weight.Piles are then launched and self-upended from the side of the derrick barge and stabbed into the pile sleeves using the assistance of Remotely Controlled Vehicles (ROVs). This is followed by pile driving and grouting.
Structure of 4,9-dibromo-1,6-dioxaspiro[4.4]nona-3,8-diene-2,7-dione, C7H2Br2O4 (1993)

The molecule consists of two rings connected through a single C atom. The angle between the least-squares planes defined by the rings is 90.7 (4) o . The crystal structure consists of isolated 4,9-dibromo-1,6-dioxaspiro[4,4]nona-3,8-diene-2,7-dione molecules. The C-Br distances are 1.855 (10) and 1.837 (10) A
THE PAPILIONACEOUS ALKALOIDS: XXI. THE ALKALOIDS OF <i>LUPINUS</i> <i>PILOSUS</i> WALT. AND THE STRUCTURE OF TETRALUPINE (1955)

The alkaloidal extract from Lupinus pilosus Walt. was found to contain two alkaloids, one widely occurring one, d-lupanine, and one which had already been reported to occur in this plant, i.e., d-epilupinine, but no lupinine. The alkaloid tetralupine has been found by direct comparison of the bases and their corresponding salts and by their infrared absorption spectra to be identical with dl-epilupinine. A study of the infrared absorption spectra of lupinine and epi-lupinine leads to the same conclusion as the chemical evidence, i.e., that in the former the hydroxymethylene group occupies the axial position whereas in epilupinine this group is in the equatorial position.
Selective Detection of Zinc Ions with Novel Luminescent Lanthanide Probes (2003)

Strahlendes Beispiel: Eine bemerkenswerte Verstärkung der Lumineszenz des TbIII-Komplexes 1 wird bei Zugabe von ZnII-Ionen beobachtet (siehe Bild). Durch seine ausgeprägte Selektivität für ZnII-Ionen und eine Lumineszenz-Lebensdauer im Millisekundenbereich eignet sich 1 hervorragend als Prototyp für die Entwicklung langlebiger ZnII-empfindlicher Lumineszenz-Chemosensoren. A=Lichtabsorption, ET=Energietransfer, E=Lichtemission. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2001/2003/z51122_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
An Investigation of N-Substituted methionine derivatives for food supplementation (1975)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXT An Investigation of N-Substituted methionine derivatives for food supplementationRalph. DamicoCite this: J. Agric. Food Chem. 1975, 23, 1, 30–33Publication Date (Print):January 1, 1975Publication History Published online1 May 2002Published inissue 1 January 1975https://pubs.acs.org/doi/10.1021/jf60197a025https://doi.org/10.1021/jf60197a025research-articleACS PublicationsRequest reuse permissionsArticle Views136Altmetric-Citations19LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Thermal noise and coating optimization in multilayer dielectric mirrors (2011)

Optical multilayer coatings of high-reflective mirrors significantly determine properties of Fabry-Perot resonators. Thermal (Brownian) noise in these coatings produce excess phase noise which can seriously degrade the sensitivity of high-precision measurements using these cavities. In particular, it is one of the main limiting factors at the current stage in laser gravitational-wave detectors (for example, project LIGO). We present a method to calculate this effect accurately and analyze different strategies to diminish it by optimizing the coating. Traditionally, the effect of the Brownian noise is calculated as if the beam is reflected from the very surface of the mirror's coating. However, the beam penetrates the coating, and Brownian expansion of the layers leads to dephasing of interference in the coating and consequently to an additional change in the reflected amplitude and phase. Fluctuations in the thickness of a layer change the strain in the medium and hence, due to a photoelastic effect, change the refractive index of this layer. This additional effect should also be considered. It is possible to reduce the noise by changing the total number and thicknesses of high and low refractive layers preserving the reflectivity. We show how an optimized coating may be constructed analytically rather than numerically as before. We also check the possibility of using internal resonant layers, an optimized cap layer, and double mirrors to decrease the thermal noise.
Production of <scp>d</scp>-Allulose with <scp>d</scp>-Psicose 3-Epimerase Expressed and Displayed on the Surface of <i>Bacillus subtilis</i> Spores (2016)

The production of d-allulose is usually conducted via isolated-enzyme or whole-cell biocatalysis reactions. In the present study, an innovative biocatalyst, d-psicose 3-epimerase (DPEase) from Clostridium scindens ATCC 35704, presented on the surface of Bacillus subtilis spores, was applied for d-allulose production. DPEase was fused at the C-terminus of the anchoring protein, CotZ, via a peptide linker, and trophic genes were used as selection markers during the chromosomal integration. The optimal temperature and pH of the fusion protein CotZ-DPEase were 55 °C and pH 7.5-8.0, respectively, and the anchored DPEase exhibited high thermostability. Under optimal conditions, 30 g/L of recombinant spores can produce 85 g/L d-allulose from 500 g/L d-fructose after 12 h, and 60% of the yield was maintained after five cycles of utilization. Therefore, this biocatalyst system, capable of expressing and immobilizing DPEase on the spore surface of B. subtilis, was an appropriate alternative for d-allulose production.