gebhart/patrepeval huggingface dataset:
Ultrastructural studies on neuroblastoma. Evaluation of cytodifferentiation and correlation of morphology and biochemical and survival data (1978)

Fifteen cases of neuroblastoma, ganglioneuroblastoma and ganglioneuroma were studied by electron microscopy. Ultrastructural features of cytodifferentiation, including numbers of dense core neurosecretory granules (NSG) and neuritic processes, were used to evaluate variation within the neuroblastoma group to determine whether differences in cytodifferentiation exist where light microscopic variations are not evident. These studies revealed that undifferentiated neuroblastomas do show ultrastructural variations not evident by light microscopy. The ultrastructural findings for each case were compared with initial urinary catecholamine excretory patterns, the latter having recently been shown to have valuable prognostic significance. There was a positive correlation, in the undifferentiated neuroblastomas, between increased numbers of NSG and prognostically favorable biochemical excretory patterns. Conversely, low numbers of NSG were associated with an unfavorable biochemical pattern and fatal clinical course. These correlations between ultrastructural differentiation and the biochemical secretory pattern indicate that ultrastructural evaluation of undifferentiated neuroblastomas would appear to have prognostic value, particularly in cases lacking initial biochemical data or as an adjunct to biochemical studies.
Incremental detection of text on road signs from video with application to a driving assistant system (2004)

This paper proposes a fast and robust framework for incrementally detecting text on road signs from natural scene video. The new framework makes two main contributions. First, the framework applies a Divide-and-Conquer strategy to decompose the original task into two sub-tasks, that is, localization of road signs and detection of text. The algorithms for the two sub-tasks are smoothly incorporated into a unified framework through a real time tracking algorithm. Second, the framework provides a novel way for text detection from video by integrating 2D features in each video frame (e.g., color, edges, texture) with 3D information available in a video sequence (e.g., object structure). The feasibility of the proposed framework has been evaluated on the video sequences captured from a moving vehicle. The new framework can be applied to a driving assistant system and other tasks of text detection from video.
Immunochemical Characterization of Two Activator Proteins Stimulating Enzymic Sphingomyelin Degradation in vitro Absence of One of them in a Human Gaucher Disease Variant (1986)

Two nonenzymic activator proteins shown previously to strongly stimulate enzymic sphingomyelin degradation in vitro were purified from human Gaucher type 1 and control spleen. Activator A1 (molecular mass 6,500 Da) had affinity for ConA-Sepharose, while activator A2 (molecular mass 3,500 Da) did not. Monospecific antibodies to each activator protein were prepared in rabbits by immunization with protein purified from type 1 Gaucher spleen. A1 and A2 activators from Gaucher type 1 spleen were shown to be immunochemically identical to A1 and A2 activators from control spleen. However, A1 and A2 activators, whether isolated from Gaucher type 1 or control spleen, were shown to be distinct proteins. Immunochemical examination of all collected fractions during the purification revealed the existence of a third activator (molecular mass 6,000 Da), which was antigenically identical to A1 activator but had no affinity for ConA-Sepharose. The two forms of A1 activator showed similar mobility on immunoelectrophoresis differing from that of A2 activator. Fibroblast extracts from controls and patients with different variants of Gaucher disease were investigated using immunodiffusion against antisera to A1 or A2 activator. In contrast to normal and Gaucher (types 1, 2 and 3) cell extracts, those of a Gaucher patient with normal glucosylceramidase activity had no visible precipitin line towards the antiserum against the two forms of A1 activator. The lack of crossreacting material to antibodies against A1 activator was confirmed by radial immunodiffusion and rocket immunoelectrophoresis. A1 activator stimulated the basal glucosylceramidase activity 5-6 fold in fibroblasts from this patient, whereas the normal effect was only a 1.2-1.5-fold stimulation. The immunological results together with the biochemical data provide evidence for the lack of an activator protein in a variant form of human Gaucher disease for the first time.
Oculomotor Biofeedback Therapy for Exotropia (1982)

Twelve exotropes of various types received oculomotor biofeedback therapy at State College of New York (SUNY) University Optometric Center. Feedback of a variable pitch tone which reflected changes in ocular vergence reinforced motor control of eye posture. Patients were trained to achieve and sustain alignment in a variety of viewing situations. The six intermittent exotropes in the study who did not have amblyopia or prior history of unsuccessful surgical or orthoptic therapy achieved the highest recovery rating after training. The amblyope and those who had orthoptic training learned to voluntarily correct their eye position, although they did not achieve as acute a sensitivity to loss of alignment as did the others. Therapy restored eye control at near in a young constant exotrope whose condition resulted from severe neurological dysfunction. A constant postsurgical exotrope who had no ability for sensory fusion made little progress. Advantages of oculomotor biofeedback therapy are shorter treatment time, elimination of lengthy home training exercises, and enhanced patient motivation.
A virtual prototyping approach to mold design (2003)

Mold design is a complex process involved in many decision factors and often requires prototypes to assess the assemblability and demouldability of the design. Virtual prototyping (VP) is an alternative to hardware prototyping in which analysis of designs can be done without manufacturing physical samples. The paper presents a virtual prototyping environment supporting mold design in which the mold virtual prototype is generated by combining automated and interactive approaches. The generated virtual prototype can be input into a virtual reality environment for visualization and design evaluation by performing virtual assemble and physical-based injection moving simulation. By creating a VP that allows for assessing assemblability and demouldability early in the mold design process, a design can be modified to accommodate assemblability and demouldability before final stages of design are reached.
SEPARATION OF POLONIUM FROM BISMUTH BY DISTILLATION (1953)

C. The coefficient for Bi was found to be approximately 5 x 10/sup -22/ and 5 x l0/sup - 10/ square centimeters per second at 150 and 200 deg C, respectively. This report describes briefly some of the mathematics of diffusion phenomema and how the coefficients are calculated from experimental data. The experimental method and sources of error are discussed. The data above are presented in detail in tubular form. Several typical autoradiographs of foils used in the experiments are included. A methcd of making thin Bi sheets is described, and pictures showing grain size and structure are attached. An appendix describes a correction necessary for alpha counters when thick sources are used. (auth)
Molecularly Imprinted Polymer Sensors for the Detection of Phosphate in Agriculture (2017)

Molecularly imprinted polymers (MIPs) are biomimetic sensing elements that combine the accuracy and highly specific binding affinity of a biosensor, with the robustness and reusability associated with artificial electrochemical sensors.
This thesis investigates the application of a MIP sensor to address the challenge of phosphate detection in precision agriculture. Traditional chemical sensing approaches using portable electrochemical sensors display a significant cross-interference between inorganic phosphate and other nutrient ions. This is due to the low position of phosphate in the Hofmeister Selectivity Series for anions, its high electronegativity and its pH dependent structure, resulting in a molecule that is very difficult to detect.
To address this challenge, a sensor was created by spin coating a phosphate selective MIP onto a substrate containing a series of electrodes. These electrode devices allowed for electrical measurements to be taken using an inductance, capacitance and resistance (LCR) testing station, and to observe the change in the materials dielectric constant as the binding sites become occupied by the target analyte. The devices underwent several design reiterations to produce an optimised setup consisting of 100 interdigitated chrome electrodes with a width of 1 μm and a separation distance of 1 μm on a quartz substrate.
The final electrode design was used to carry out a nutrient cross-interference study across several polymer permutations. The purpose of this was to develop an optimised MIP formulation for binding specifically to inorganic phosphate ions. From this study, an optimal phosphate selective MIP was identified, based upon a binding site constructed from methacrylic acid around a diphenyl phosphate template molecule. During capacitance measurements, this MIP formulation demonstrated a clear preferential response to phosphate (1610 pF) over the average capacitance results observed following exposure to the competing nitrate (1286 pF) and sulphate (1212 pF) nutrients tested in the cross-interference study.
LA REFORMA FISCAL, MÁS BUENA QUE MALA (2002)

LAS REFORMAS FISCALES SON MAS BUENAS QUE MALAS, CON IMPORTANTES ELEMENTOS POSITIVOS QUE VAN EN EL CAMINO CORRECTO PARA ATACAR LA EVASION Y ELUSION DEL PAGO DE IMPUESTOS DE LOS SECTORES CON MAYORES RECURSOS. POR ELLO, LOS EMPRESARIOS REALIZAN UNA CAMPANA EN BUSCA DE EVITAR CUBRIR ESTAS CONTRIBUCIONES, A PESAR DE QUE REPRESENTAR N 73 MIL MILLONES DE PESOS ADICIONALES A LOS INGRESOS GUBERNAMENTALES, ASEGURO EL ACADEMICO DE LA FACULTAD DE ECONOMIA, EMILIO CABALLERO URDIALES. PARA MINIMIZAR LOS CONFLICTOS, RECOMENDO AL GOBIERNO FEDERAL EFECTUAR UN ACUERDO POLITICO CON TODOS LOS SECTORES DE LA SOCIEDAD, SIN QUE POR ELLO DEJEN DE PAGAR IMPUESTOS. EN CONFERENCIA DE PRENSA, MODERADA POR EL JEFE DE LA DIVISION DE ESTUDIOS PROFESIONALES DE LA FACULTAD, JOSE LUIS VICTORIA TOSCANO, EL ESPECIALISTA EN TEORIA ECONOMICA PRECISO QUE EL PROBLEMA DE FONDO ES QUE EL IMPUESTO AL VALOR AGREGADO (IVA) NO FUE TOCADO, LO CUAL RESULTA POSITIVO PORQUE CUALQUIER INCREMENTO -SOBRE TODO EN ALIMENTOS Y MEDICINAS COMO PROPONIA EL GOBIERNO FEDERAL- HUBIERA AFECTADO A LOS MAS DESPROTEGIDOS. ASEGURO QUE LOS ERRORES Y CONTRADICCIONES QUE APARECEN EN LAS REFORMAS FISCALES SON SOLO DE FORMA Y PUEDEN CORREGIRSE; EL PROPOSITO ES QUE PAGUEN QUIENES TIENEN MAS. PRECISO QUE SE MODIFICARON EL IMPUESTO SOBRE LA RENTA (ISR), LOS IMPUESTOS ESPECIALES SOBRE PRODUCCION Y SERVICIOS (IEPS) Y SE CREO UNO NUEVO: ARTICULOS SUNTUARIOS.
TFA-Sensitive Arylsulfonylthiourea-Assisted Synthesis of N,N‘-Substituted Guanidines (2003)

An efficient synthesis of N,N'-substituted guanidine derivatives was developed via an aromatic sulfonyl-activated thiourea intermediate. The use of certain aromatic sulfonamides, such as PbfNH(2), as the key reagent to incorporate a TFA-labile guanidine protection group greatly facilitates solid-phase synthesis of N,N'-substituted guanidine compounds.
<i>CYP1A2</i> Genetic Polymorphisms are Associated with Treatment Response to the Antidepressant Paroxetine (2010)

Genetic variants in the CYP1A2 region may be indicators of treatment response in MDD patients to paroxetine.
Electronic Interactions and Thermal Disorder in Molecular Crystals Containing Cofacial Pentacene Units (2005)

We computed the intermolecular electronic coupling and the band structure of three pentacene derivatives that stack cofacially in one or two dimensions. We rationalize the results building a map of the coupling between HOMOs and LUMOs of isolated pentacene molecules as a function of the relative molecular orientation and finding the position on such map of the actual molecular pairs. The apparently chaotic dependence of the intermolecular coupling from the crystal structure is explained, and directions for the design of materials with improved electric transport properties are given. We run molecular dynamics simulations to explore the variation of the intermolecular coupling due to the thermal motions. It is shown that, even in the crystal phase, the limited conformational space explored at room temperature is large enough to produce consistent variation in the intermolecular coupling. The consequences of this finding on the practicability of the transport properties of organic materials are analyzed.
Antithrombotic and Anticoagulant Activities of a Low Molecular Weight Fucoidan by the Subcutaneous Route (1999)

Fucoidans (high-molecular-weight sulfated polysaccharides extracted from brown seaweeds) have anticoagulant and antithrombotic effects. They inhibit thrombin by catalyzing both serpins (antithrombin and heparin cofactor II) according to their chemical structures and origins. In this study, a low-molecular-weight (LMW) fucoidan of 8 kDa was obtained by chemical degradation of a high-molecular-weight fraction. The antithrombotic and anticoagulant activities of this new compound were compared to those of a low-molecular-weight heparin (LMWH), dalteparin, following subcutaneous administration to rabbits. This LMW fucoidan exhibited dose-related venous antithrombotic activity, with an ED80 of about 20 mg/kg, 2 h after a single subcutaneous injection. Its activity was comparable to that of dalteparin (close to 200 anti-Xa IU/kg) and was maximal 30 min after a single subcutaneous injection. The activity remained stable (about 70%) from 1 to 4 h after injection, but disappeared by 8 h. The antithrombotic activity was not associated with either a prolongation of the thrombin clotting time (TCT) or an increase in anti-Xa activity, contrary to dalteparin. A slight prolongation of APTT occurred with both compounds. This venous antithrombotic activity was associated with a decrease in ex vivo thrombin generation and with a significant increase in the lag phase in a thrombin generation test. LMW fucoidan thus has potent antithrombotic activity and a potentially weaker haemorrhagic effect (i.e. a smaller effect on coagulation tests and a smaller prolongation of the bleeding time) than dalteparin.
Linux + Certification Bible (2002)

From the Publisher:
The only guide you need for Linux+ exam success You're holding in your hands the most comprehensive and effective guide available for the CompTIA Linux+ exam. Trevor Kay delivers incisive, crystal-clear explanations of every Linux+ topic, highlighting exam-critical concepts and offering hands-on tips that can help you in your real-world career. Throughout, he provides pre-tests, exam-style assessment questions, and scenario problems  everything you need to master the material and pass the exam. Inside, you'll find complete coverage of Linux+ exam objectives
Get up to speed on Linux basics and understand the differences between different Linux distributionsTackle Linux installation, from planning to network configuration, dual-boot systems, and upgradesGet the scoop on managing Linux disks, file systems, and processes; implementing security; and backing up your systemLearn the ins and outs of configuring the X Window system and setting up a networkFind out how to establish users and groups, navigate the Linux file system, and use Linux system commandsDelve into troubleshooting techniques for the boot process, software, and networkingGet a handle on maintaining system hardware, from CPU and memory to peripherals
Test-Prep Software and More on CD-ROM
Test engine powered by Boson Software, with hundreds of sample questionsLinux tools, including Phatlinux, Big brother system and network monitor, Apache Web Server, Squid Web Proxy Cache, AbiWord word processor, and EncompassPlus an e-version of the book
Boson Software System Requirements: PC with Pentium 120 mhz or greater; 32 MB RAM; 500 MB free hard drivespace. See the About the CD appendix for details and complete system requirements. www.hungryminds.com
Author Biography: About the Author
Trevor Kay is A+, Network+, Server+, and Linux+ certified. Trevor is currently a technical consultant and author. He has worked as an IT helpdesk consultant, technical support specialist, and network administrator, and played a key role in Y2K preparations at one of Canada's largest financial organizations.
Semantic mapping using object-class segmentation of RGB-D images (2012)

For task planning and execution in unstructured environments, a robot needs the ability to recognize and localize relevant objects. When this information is made persistent in a semantic map, it can be used, e. g., to communicate with humans. In this paper, we propose a novel approach to learning such maps. Our approach registers measurements of RGB-D cameras by means of simultaneous localization and mapping. We employ random decision forests to segment object classes in images and exploit dense depth measurements to obtain scale-invariance. Our object recognition method integrates shape and texture seamlessly. The probabilistic segmentation from multiple views is filtered in a voxel-based 3D map using a Bayesian framework. We report on the quality of our object-class segmentation method and demonstrate the benefits in accuracy when fusing multiple views in a semantic map.
Buoyancy Regulation in a Strain of Aphanizomenon flos-aquae (Cyanophyceae): the Importance of Carbohydrate Accumulation and Gas Vesicle Collapse (1986)

Buoyancy regulation in light-limited continuous cultures of Aphanizomenon 30s-aquae was studied. Gas vesicle collapse did not occur during growth under a light-dark cycle. Only cultures with growth rates less than 20% of the maximal growth rate were positively buoyant. The loss of buoyancy at higher growth rates was due to a lower gas vesicle content in the cells. Carbohydrate accumulation was the main factor which caused buoyancy loss if the cells were shifted from low to high photon flux densities. In these experiments turgor-induced gas vesicle collapse occurred only in cultures adapted to long light periods, and several hours after the cells had lost buoyancy due to ballast increase. The results are discussed in relation to adaptation patterns in photosynthesis and carbon metabolism caused by intermittent light.
Energy Harvesting Chip and the Chip Based Power Supply Development for a Wireless Sensor Network (2008)

In this study, an energy harvesting chip was developed to scavenge energy from artificial light to charge a wireless sensor node. The chip core is a miniature transformer with a nano-ferrofluid magnetic core. The chip embedded transformer can convert harvested energy from its solar cell to variable voltage output for driving multiple loads. This chip system yields a simple, small, and more importantly, a battery-less power supply solution. The sensor node is equipped with multiple sensors that can be enabled by the energy harvesting power supply to collect information about the human body comfort degree. Compared with lab instruments, the nodes with temperature, humidity and photosensors driven by harvested energy had variation coefficient measurement precision of less than 6% deviation under low environmental light of 240 lux. The thermal comfort was affected by the air speed. A flow sensor equipped on the sensor node was used to detect airflow speed. Due to its high power consumption, this sensor node provided 15% less accuracy than the instruments, but it still can meet the requirement of analysis for predicted mean votes (PMV) measurement. The energy harvesting wireless sensor network (WSN) was deployed in a 24-hour convenience store to detect thermal comfort degree from the air conditioning control. During one year operation, the sensor network powered by the energy harvesting chip retained normal functions to collect the PMV index of the store. According to the one month statistics of communication status, the packet loss rate (PLR) is 2.3%, which is as good as the presented results of those WSNs powered by battery. Referring to the electric power records, almost 54% energy can be saved by the feedback control of an energy harvesting sensor network. These results illustrate that, scavenging energy not only creates a reliable power source for electronic devices, such as wireless sensor nodes, but can also be an energy source by building an energy efficient program.
Distributed Energy Adaptive Computing (2010)

Fueled by burgeoning online services, power and thermal issues are becoming crucial both in terms of utility costs and environmental impact. In this paper, we motivate an approach that puts power/thermal issues at the heart of distributed computing, and strives to alter the behavior of the computation in order to dynamically adjust to changing energy constraints. The paper discusses three distributed energy adaptation paradigms and shows why they are essential for sustainable computing. The paper also compares and contrasts two basic techniques for energy adaptation in servers, namely power capping and use of sleep modes.
Structure of Protein Phosphatase Methyltransferase 1 (PPM1), a Leucine Carboxyl Methyltransferase Involved in the Regulation of Protein Phosphatase 2A Activity (2004)

The important role of the serine/threonine protein phosphatase 2A (PP2A) in various cellular processes requires a precise and dynamic regulation of PP2A activity, localization, and substrate specificity. The regulation of the function of PP2A involves the reversible methylation of the COOH group of the C-terminal leucine of the catalytic subunit, which, in turn, controls the enzyme's heteromultimeric composition and confers different protein recognition and substrate specificity. We have determined the structure of PPM1, the yeast methyltransferase responsible for methylation of PP2A. The structure of PPM1 reveals a common S-adenosyl-l-methionine-dependent methyltransferase fold, with several insertions conferring the specific function and substrate recognition. The complexes with the S-adenosyl-l-methionine methyl donor and the S-adenosyl-l-homocysteine product and inhibitor unambiguously revealed the co-substrate binding site and provided a convincing hypothesis for the PP2A C-terminal peptide binding site. The structure of PPM1 in a second crystal form provides clues to the dynamic nature of the PPM1/PP2A interaction.
Visual Data Mining : Techniques and Tools for Data Visualization and Mining (2002)

From the Publisher:
Data mining techniques offer marketing analysts a better understanding of customer buying habits. That data can then be used to develop new marketing campaigns and new products. New visual mining tools are becoming widely available, and can provide a quick and easily accessible way of retrieving information. These visual techniques also have the ability to make it possible for nontechnical business managers to understand their markets and make more savvy business decisions.
The eXtensible Access Method (XAM) Standard (2009)

Recent developments in the storage industry have resulted in the creation of an industry standard application programmer’s interface (API) known as XAM, the eXtensible Access Method. The XAM API focuses on the creation and management of reference information (otherwise known as fixed content). Storage vendors supporting the XAM API will provide new benefits to applications that are creating and managing large amounts of fixed content. The benefits described by this paper merit consideration and research by developers creating applications for Digital Curators.