gebhart/patrepeval huggingface dataset:
GDS-3 STUDY ON DESIGN OF CROSSED HELICAL GEARS(GEAR DESIGN AND SYNTHESIS) (2001)

Since the tooth surfaces of the crossed helical gears have an involute helicoid surface, the production and assembly of the gears are easy compared with other kind of gears. On the other hand, Because the contacting tooth surfaces of crossed helical gears are engaged in a point contact, the load carrying capacity of crossed helical gears is quite limited. Theoretical studies on crossed helical gears have been published [1-5]. Since the engagement of crossed helical gears is dealt with in three-dimensional space, the design formulas for the crossed helical gears become complex. In this study, we developed a new designing method in which shaft angle, reduction ratio and center distance can be arbitrarily set using dual vectors. In addition, using the crossed helical gears designed by our method, tooth contact analysis was carried out to examine the effect of the design conditions of the crossed helical gears on Hertzian pressure between tooth surfaces.
Induction of fibroblast growth factor 10 (FGF10) in the ileal crypt epithelium after massive small bowel resection suggests a role for FGF10 in gut adaptation (2008)

We have previously reported that fibroblast growth factor 10 (FGF10) is crucial for the survival and proliferation of progenitor cells during embryonic gastrointestinal development. We sought to characterize the potential role of FGF10 signaling in the adaptive response following small bowel resection. Adult wild-type and Fgf10(LacZ) mice underwent 50% small bowel resection (SBR) or sham operation. Tissues were harvested 24 or 48 hr after surgery for histology, immunohistochemistry, and in situ hybridization. After SBR, Fgf10 expression was demonstrated in the epithelium at the base of the crypts. Moreover, there was a statistically significant increase in proliferating cells and goblet cells after SBR. In vitro studies using rat intestinal epithelial crypt (IEC-6) cells exposed to medium with or without recombinant FGF10 showed increased proliferation and phosphorylation of Raf and AKT with the addition of FGF10. Our results suggest that FGF10 may play a therapeutic role in diseases involving intestinal failure.
Enhancement of lung adenoma formation by neonatal thymectomy in mice treated with 7,12‐dimethylbenz(a)anthracene or urethan (1967)

Abstract The influence of neonatal thymectomy on lung adenoma formation in mice was investigated. SWR and Swiss mice thymectomized at 3 days of age and given a single dose of 7,12‐dimethylbenz (a) anthracene (DMBA) or urethan showed significantly higher incidences of tumors than did intact controls, when examined at various intervals after the carcinogenic treatment. These differences in the yield of tumors were manifested as early as 10 weeks after urethan administration. Levels of hemolysins and hemagglutinins in response to sheep erythrocytes were decreased in thymectomized mice as compared with normal animals. The probable relationship between enhanced susceptibility to chemical carcinogens and immunological deficit of neonatally thymectomized mice is discussed.
Reflexive autoepistemic logic and logic programming (1993)

In this paper we show that reflexive autoepistemic logic of Schwarz is a particularly convenient modal formalism for studying properties of answer sets for logic programs with classical negation and disjunctive logic programs. Syntactical properties of logic programs imply that a. natural interpretation of default logic in the logic of minimal knowledge (nonmonotonic S4F) provides also a modal representation of logic programs. Moreover, in the case of logic programs one can use reflexive autoepistemic logic which is stronger and possesses simpler semantical characterizations than the logic of minimal knowledge. Reflexive autoepistemic logic and autoepistemic logic are bi-interpretable. Consequently, our results provide embeddings of logic programs with classical negation and disjunctive programs in autoepistemic logic.
<title>The BBN Byblos Hindi OCR system</title> (2005)

The BBN Byblos OCR system implements a script-independent methodology for OCR using Hidden Markov Models (HMMs). We have successfully ported the system to Arabic, English, Chinese, Pashto, and Japanese. In this paper, we report on our recent effort in training the system to perform recognition of Hindi (Devanagari) documents. The initial experiments reported in this paper were performed using a corpus of synthetic (computer-generated) document images along with slightly degraded versions of the same that were generated by scanning printed versions of the document images and by scanning faxes of the printed versions. On a fair test set consisting of synthetic images alone we measured a character error rate of 1.0%. The character error rate on a fair test set consisting of scanned images (scans of printed versions of the synthetic images) was 1.40% while the character error rate on a fair test set of fax images (scans of printed and faxed versions of the synthetic images) was 8.7%.
Diffusion tensor imaging in cases with visual field defect after anterior temporal lobectomy. (2005)

Optic radiation showed a decreased FA value in cases after temporal lobectomy. In later stages, ADC values tended to increase and high signal intensities on T2-weighted images were observed. The FA value can be used for evaluating Wallerian degeneration of optic radiation even in the early stages after surgery.
A Dynamic Model for the Performance of Carving Skis (2003)

To analyze the behavior and the local force transfer condition by simulation techniques, the ski was modeled with 18 segments and an additional shovel segment. The elastic and damping properties of the ski were concentrated to the joints between the segments representing the bending and torsional characteristics according to measurements. The ski-snow contact comprises forces due to penetration, cutting properties of the edge and friction; new measurements were used for essential data. Since the experimental verification of the simulation results was essential, a special ski-sledge was used instead of a skier. The results on the one hand show good agreement between measured trajectories for a half turn and their simulated counterparts. On the other hand, by the simulation the discrepancy between carving radii of the deformed skis and the traveled radius became obvious — and consequently starting points for improvements. Moreover, the local force transfer along the edge shows the vertical force distribution and the positions where lateral skidding is relevant. Further utilization of the dynamic simulation, including local force distribution, should lead to more optimal design of skis and binding plates — as local stiffening of the structure — thereby enhancing sports performance and reducing the effort for recreational skiers.
Expression Signature Developed from a Complex Series of Mouse Models Accurately Predicts Human Breast Cancer Survival (2009)

Together, our data support that novel gene signature derived from mouse models of cancer can be used for predicting human cancer outcome. Our approaches set precedence that similar strategies may be used to decipher novel gene signatures for clinical utility.
Temporal stability of solid oxidizers at high temperature and humidity. Memorandum report (1985)

Chemical Warfare/Biological Warfare (CW/BW) decontamination operations may rely on aqueous solutions prepared from stored solid oxidizers. Needed are data defining the shipboard storage stability of candidate oxidizers. Therefore, the stability of a series of potential decontaminants has been examined at high temperature (90 + C) and humidity (95 + % R.H.). The loss of oxidizing capacity in aliquots of the oxidizers was followed with time by iodometric titration. Calcium hypochlorite lost over 99% of its oxidizing capacity in less than two days, whereas lithium hypochlorite retained one-third oxidizing capacity for approximately twenty days. Sodium perborate, and sodium persulfate were very hygroscopic and unstable with time. H-48 decomposed in approximately two days, while sodium isocyanurate lost about 80% of its oxidizing capacity in two weeks. The data presented documents severe stability problems of one sort or another with all the materials tested, although overall the sodium isocyanurate appeared to be the more stable candidate undr extreme conditions. In any case, packaging and storage considerations are shown to be important for any potential decontaminant to be stored under environmentally severe conditions.
Single Pixel Camera Approach for Biometrics (2017)

The work describes implementation of a single-pixel camera approach for development of biometrics authentication system as well as new ways of performing spatial light modulation required for this approach – by using a liquid crystal display or diffusely scattering medium. It is shown that such improvements of the single-pixel camera approach allow us to avoid using a conventional optical system thus performing miniaturization of the entire system.
The Association of Metabolic Disorders with the Metabolic Syndrome Is Different in Men and Women (2003)

These results are consistent with the concept that a clustering of metabolic disorders occurs frequently in both women and men. However, the contribution of several metabolic disorders to the metabolic syndrome is different in men and women. This finding supports the concept that different criteria are necessary to define the metabolic syndrome in women and men.
Optical Atomic Clocks Based Upon Neutral Atoms (2007)

We report new measurements for two optical atomic clocks. The calcium clock uses freely expanding atoms, while the ytterbium clock uses lattice-confined atoms to suppress Doppler effects. We measure a fractional instability between the clocks of 4 × 10−16 for 100 s averaging time.
4-Hydroperoxycyclophosphamide purging of breast cancer from the mononuclear cell fraction of bone marrow in patients receiving high-dose chemotherapy and autologous marrow support: a phase I trial. (1991)

We designed an ex vivo bone marrow treatment for breast cancer patients receiving high-dose chemotherapy and autologous bone marrow support (ABMS), using 4-hydroperoxycyclophosphamide (4-HC), an active derivative of cyclophosphamide with known activity against breast cancer. This phase I bone marrow purging trial used ficoll-separated mononuclear cells (MNC) (devoid of granulocytes and RBCs), as opposed to the buffy coat. Twenty-five patients with metastatic breast cancer were studied. Patients received three cycles of the Adriamycin (doxorubicin; Adria Laboratories, Columbus, OH), fluorouracil, and methotrexate (Duke AFM) regimen, followed by marrow harvest. An MNC fraction of marrow was prepared and treated with 4-HC in concentrations of 20 micrograms/mL (four patients), 40 micrograms/mL (four patients), 60 micrograms/mL (nine patients), or 80 micrograms/mL (eight patients) and cryopreserved. Patients then received high-dose systemic cyclophosphamide, cisplatin, and carmustine, followed by infusion of the purged marrow. The study end point was marrow engraftment, defined as WBC count greater than 1,000 cells per microliter. At the first three dose levels (20, 40, and 60 micrograms/mL 4-HC), there was no significant delay in time to engraftment (19, 20, and 23 days, respectively) compared with the unpurged historical controls (17 days). At 80 micrograms/mL, engraftment was significantly delayed compared with the lower concentrations (P = .027), and further escalation of 4-HC was not attempted. A significant correlation was observed between the time of leukocyte engraftment and the 4-HC concentration (P = .017). With a methylcellulose-based tissue culture assay, we demonstrated a statistically significant correlation between the colony-forming unit-granulocyte-macrophage (CFU-GM) content in the purged marrow and the days to engraftment. Ninety-five percent of patients responded clinically to the entire program, 55% of them completely. Longer follow-up is required to assess the ultimate benefit of intensive therapy on long-term survival.
Simultaneous Determination of Antimony(III) and Molybdenum(VI) by Adsorptive Stripping Voltammetry Using Quercetin as Complexing Agent (2012)

Abstract A sensitive and selective voltammetric method for simultaneous determination of Sb(III) and Mo(VI) using Quercetin (Q) as complexing agent is described. Optimal conditions were found to be: pH 3.7, C Q =6.0 µmol L −1 and E acc =−0.10 V. The LOD (3 σ ) for Sb(III) are 0.076 and 0.040 µg L −1 , whereas for Mo(VI) are 0.086 and 0.048 µg L −1 with t acc of 60 and 120 s, respectively. The method was validated using synthetic sea water (ASTM D665) and was applied to the determination of Sb(III) and Mo(VI) in natural waters with satisfactory results.
Structure of myotoxin II, a catalytically inactive Lys49 phospholipase A<sub>2</sub>homologue from<i>Atropoides nummifer</i>venom (2006)

Lys49 snake-venom phospholipase A2 (PLA2) homologues are highly myotoxic proteins which, although lacking catalytic activity, possess the ability to disrupt biological membranes, inducing significant muscle-tissue loss and permanent disability in severely envenomed patients. Since the structural basis for their toxic activity is still only partially understood, the structure of myotoxin II, a monomeric Lys49 PLA2 homologue from Atropoides nummifer, has been determined at 2.08 angstroms resolution and the anion-binding site has been characterized.
Restricted diffusion of highly dense starburst-dendritic poly(amido amine) in porous glasses (1992)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTRestricted diffusion of highly dense starburst-dendritic poly(amido amine) in porous glassesYihong Guo, Kenneth H. Langley, and Frank E. KaraszCite this: Macromolecules 1992, 25, 19, 4902–4904Publication Date (Print):September 1, 1992Publication History Published online1 May 2002Published inissue 1 September 1992https://pubs.acs.org/doi/10.1021/ma00045a012https://doi.org/10.1021/ma00045a012research-articleACS PublicationsRequest reuse permissionsArticle Views60Altmetric-Citations11LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Multi-model tracking using team actuation models (2006)

Robots need to track object. Object tracking efficiency completely depends on the accuracy of the motion model and of the sensory information. Interestingly, when multiple team members can actuate the object being tracked, the motion can become highly discontinuous and nonlinear. We have previously developed a successful tracking approach that switches among target motion models as a function of one robot's actions. In this paper, we report on a tracking approach that can use a dynamic multiple motion model based on a team coordination plan. We present the multi-model probabilistic tracking algorithms in detail and present empirical results both in simulation and in a human-robot Segway soccer team. The team coordination plan allows the robot to much more effectively track mobile targets
Cerebellin1 is a novel orexigenic factor which potently increases food intake via hypothalamic neuropeptide Y release (2009)

Background: Cerebellin1 (Cbln1) is a highly conserved 16 amino acid neuropeptide. Cbln1 was originally identified in the cerebellum and has since been found to have widespread distribution in the CNS and periphery. High levels of Cbln1 mRNA expression are found in the hypothalamus, a critical area of the brain involved in appetite regulation. However, the role of Cbln1 in the regulation of food intake and body weight is not known.
Digital Control of a Buck Converter Based on Input-Output Linearization. An Interpretation Using Discrete-Time Sliding Control Theory (2019)

This paper presents the analysis and design of a PWM nonlinear digital control of a buck converter based on input-output linearization. The control employs a discrete-time bilinear model of the power converter for continuous conduction mode operation (CCM) to create an internal current control loop wherein the inductor current error with respect to its reference decreases to zero in geometric progression. This internal loop is as a constant frequency discrete-time sliding mode control loop with a parameter that allows adjusting how fast the error is driven to zero. Subsequently, an outer voltage loop designed by linear techniques provides the reference of the inner current loop to regulate the converter output voltage. The two-loop control offers a fast transient response and a high regulation degree of the output voltage in front of reference changes and disturbances in the input voltage and output load. The experimental results are in good agreement with both theoretical predictions and PSIM simulations.
EPITAXY AND DEVICE APPLICATIONS OF GaAs ON Si (1987)

Recent results of GaAs on Si epitaxy and device fabrication are reviewed. Emphasis is on the growth initiation procedures, defect reduction processes, and integrated circuit fabrication. The effects of Si substrate orientation and substrate temperature on the GaAs layer properties are detailed. Stress related issues are also discussed.
Differentiation of benign and malignant sub-1 cm breast lesions using dynamic contrast enhanced MRI (2003)

The purpose of this work is to assess the additional benefit of MRI-based morphology and quantification of contrast enhancement in the differential diagnosis of sub-1cm breast lesions. Forty-three women with suspected breast cancer were examined using X-ray mammography, ultrasound mammography, and MRI. Dynamic contrast imaging was performed and relative enhancement at various time-points was calculated. The dynamic data was also processed using a two-compartment pharmacokinetic model. Radiological interpretation of high-resolution post-contrast images revealed a similar accuracy (69%) compared to X-ray mammography (69%) and ultrasound mammography (67%). The best individual parameter calculated from the dynamic images was found to be the exchange rate constant which revealed a diagnostic accuracy of 0.74 +/- 0.08. When information from the post-contrast images and dynamic data was combined in a logistic regression model a diagnostic accuracy of 0.92 +/- 0.03 was achieved. In conclusion, MR imaging of small breast lesions is feasible and the incorporation of quantitative MR derived parameters is beneficial.
Genetic Defect in Phospholipase Cδ1 Protects Mice From Obesity by Regulating Thermogenesis and Adipogenesis (2011)

PLCδ1 has essential roles in thermogenesis and adipogenesis and thereby contributes to the development of obesity.
Abstract 1333: Advanced Cardiac Imaging Uncovers Diagnosis in Patients With Persistent Chest Pain (2009)

Possible involvement of 18S rRNA fragment 1638-1650 including basements of the helices h44 and h28 and nucleotides of the ribosomal decoding site in the cap-independent translation initiation on plant ribosomes is studied. This rRNA fragment is shown to be accessible for complementary interactions within the 40S ribosomal subunit. It is found that the sequence complementary to the 18S rRNA fragment 1638-1650 is able to enhance efficiency of a reporter mRNA translation when placed just after the initiation codon. The results obtained indicate that in the course of the cap-independent translation initiation, complementary interactions can occur between mRNA coding sequence and 18S rRNA fragment in the region of the ribosomal decoding site.
Locally advanced unresectable gastric cancer successfully resected after neoadjuvant chemotherapy with FADE regimen (1990)

The prognosis of unresectable advanced gastric cancer is extremely poor. We tried a neoadjuvant chemotherapy in locally advanced unresectable stomach cancer diagnosed by initial explo-laparotomy. After chemotherapy with the FADE regimen (5-fluorouracil + adriamycin + cisplatin + etoposide), the patient was diagnosed clinically as a complete response state on re-staging with radiological gastrointestinal study, fiber-gastroscopy and computerized tomography. During the second-look operation, the advanced cancer was completely resected and the pathological diagnosis was early gastric cancer (EGC) type IIc, stage II (T1N2Mo).
Syntheses of Heterocyclic Compounds of Nitrogen LIII (1951)

1) By the application of dimethylamine or diethylamine on β-bromethylidene diethyl ether, dimethyl- or diethyl-aminoacetal was obtained in a good yield.2) Grignard reagent was applied on 2-benzylideneamino- and 5-chloro-2-benzylideneamino-pyridines to form addition products which were condensed with β-dimethylaminoethyl or β-diethyaminoethyl chloride to obtain four kinds of pyribenzamine compounds.
Application of Enantioselective Radical Reactions:  Synthesis of (+)-Ricciocarpins A and B (2004)

Enantioselective synthesis of (+)-ricciocarpins A and B has been achieved in 41 and 45% overall yields, respectively, starting from a beta-substituted oxazolidinone. The key steps in the strategy are an enantioselective conjugate radical addition and the addition of a furyl organometallic to a key aldehyde intermediate. [reaction--see text]
PILOT_PROTEIN: Identification of Unmodified and Modified Proteins via High-Resolution Mass Spectrometry and Mixed-Integer Linear Optimization (2012)

A novel protein identification framework, PILOT_PROTEIN, has been developed to construct a comprehensive list of all unmodified proteins that are present in a living sample. It uses the peptide identification results from the PILOT_SEQUEL algorithm to initially determine all unmodified proteins within the sample. Using a rigorous biclustering approach that groups incorrect peptide sequences with other homologous sequences, the number of false positives reported is minimized. A sequence tag procedure is then incorporated along with the untargeted PTM identification algorithm, PILOT_PTM, to determine a list of all modification types and sites for each protein. The unmodified protein identification algorithm, PILOT_PROTEIN, is compared to the methods SEQUEST, InsPecT, X!Tandem, VEMS, and ProteinProspector using both prepared protein samples and a more complex chromatin digest. The algorithm demonstrates superior protein identification accuracy with a lower false positive rate. All materials are freely available to the scientific community at http://pumpd.princeton.edu.