gebhart/patrepeval huggingface dataset:
Characterization of isomeric dimethylfuranocoumarins by electron impact ionization and surface and gaseous collision activation mass spectrometry (1989)

Five dimethylfuranocoumarin isomers have been examined by conventional electron impact (EI) mass spectrometry and by collisional activation tandem mass spectrometry using collisions upon both gaseous and solid targets. Kiloelectron-volt collision-induced dissociation (CID) experiments were conducted upon the molecular cation (M+.), the molecular anion (M−.) and the protonated molecule ([M + H]+). Low-energy (electron-volt) CID and surface-induced dissociation (SID) experiments were performed on the molecular cation (M+.) as a function of collision energy in order to vary the internal energy deposited into the ion. Characteristic fragment ions were observed in the EI mass spectra of each isomer, which allowed for their clear distinction. High-energy CID performed on the molecular cation (M+.) yielded similar daughter ion spectra for each isomer, although small variations in the relative intensities of selected fragment ions allowed for their distinction. Nearly identical CID spectra were obtained for the molecular anions and protonated molecules. Low-energy CID performed upon the molecular cation under multiple-collision conditions at collision energies ranging from 10 to 29 eV yielded nearly identical daughter ion spectra for all but one isomer, suggesting that isomerization to a common ion structure may have occurred. By contrast, ion/surface (SID) collisions on M+. were highly effective in distinguishing the various isomers in that characteristic fragment ions were obtained for each compound. Remarkable features of the SID data are the extensive degree of fragmentation recorded for these aromatic molecules, and the reduced tendency of the activated ion to undergo rearrangement to a common ion structure.
Photo-cross-linkable oligonucleotide probes for in situ hybridization assays. (2000)

In situ hybridization techniques have been an important research tool since first introduced 30 years ago, and more recently clinical applications have been expanding greatly. Still, further improvements in the assay sensitivity and protocols that are amenable to routine clinical use are desired. We use a novel photo-cross-linking technology to irreversibly bind short oligonucleotide probes to the target sequence following a hybridization period. The cross-linking agent is incorporated into the backbone of the probe and is activated to react with pyrimidines in the opposite strand by near-UV (300-370 nm) irradiation. By locking the probe to the target, very stringent wash conditions can be used that would otherwise completely remove probes that are hybridized but not cross-linked to the target. Consequently, the probe-specific signal is maximized, while the background signal is minimized to the greatest extent possible with the stringency of the wash. The use of short, photo-cross-linkable probes presents a new strategy for maximizing the sensitivity of probe hybridization or signal amplification-based in situ techniques.
Palmitoylation of KChIP Splicing Variants Is Required for Efficient Cell Surface Expression of Kv4.3 Channels (2002)

The Ca(2+)-binding proteins KChIP1-4 (KChIP3 is also known as DREAM and calsenilin) act as auxiliary subunits for voltage-gated K(+) channels in the Kv4 family. Here we identify three splicing isoforms of rat KChIP2 with variable N-terminal peptides. The two longer isoforms, which contain the 32-amino acid peptide, produce larger increases in Kv4.3 protein level and current density and more effectively localize themselves and their associated channels at the plasma membrane than the shortest variant. The 32-amino acid peptide contains potential palmitoylation cysteines. Metabolic labeling demonstrates that these cysteines in the KChIP2 isoforms, as well as the corresponding sites in KChIP3, are palmitoylated. Mutating these cysteines reduces their plasma membrane localization and the enhancement of Kv4.3 current density. Thus, palmitoylation of the KChIP auxiliary subunits controls plasma membrane localization of their associated channels.
ChemInform Abstract: Synthesis and Catalysis of Chemically Reduced Metal—Metalloid Amorphous Alloys (2013)

Abstract Review: 310 refs.
Eosinophils expressing heparin-binding EGF-like growth factor mRNA localize around lung microvessels in pulmonary hypertension. (1993)

In pulmonary hypertension, induced in rats breathing high oxygen at normobaric pressure, vascular cell hypertrophy and hyperplasia thicken the walls of lung microvessels (15-100 microns in diameter). Over a 28-day time course, new contractile cells develop from intimal precursor smooth muscle cells, which include intermediate cells and interstitial fibroblasts. Cell labeling studies in vivo have shown that these cells proliferate more than other vascular cells and that most of this activity occurs between 4 and 7 days of hyperoxia. The growth factors responsible for this proliferation are unknown. In the present study, we investigate the expression of mRNA for the epidermal growth factor (EGF)-related protein, heparin-binding EGF-like growth factor (HB-EGF), a newly discovered mitogen for fibroblasts and smooth muscle cells. Northern analysis shows HB-EGF mRNA levels to be low in normal lung but increased 100-fold by day 7 of hyperoxia. In situ hybridization identifies a select group of cells expressing HB-EGF mRNA. In normal lung, hybridizing cells are randomly distributed in the alveolar wall and space. By day 7, they increase in number and cluster around the microvessels. Histochemical techniques identify cells expressing HB-EGF mRNA as eosinophils.
Inflammation at the insertion site is not predictive of catheter-related bloodstream infection with short-term, noncuffed central venous catheters* (2002)

Local inflammation is uncommon with infected CVCs, probably because most catheter-associated infections are currently caused by coagulase-negative staphylococci, a pathogen that incites little local or systemic inflammation. Whereas overt inflammation of the insertion site should raise suspicion of CVC-related BSI caused by or Gram-negative bacilli, especially if the patient has fever or other signs of sepsis, in general, site appearance cannot be relied on to identify catheter colonization or CVC-related BSI.
Preserving Reproducibility: Provenance and Executable Containers in DataONE Data Packages (2018)

Many data packaging standards are available to researchers and data repository operators and the choice to use an existing standard or create a new one is challenging. We introduce the DataONE Data Package standard which is based on the existing OAI-ORE Resource Map standard. We describe the functionality Data Package provides, implementation considerations, compare it to existing standards, and discuss future extensions to the standard including the ability to describe execution environments via WholeTale "Tales"" and alternate serialization formats.
Effect of Self-Assembled Monolayer Modification on Indium–Tin Oxide Surface for Surface-Initiated Vapor Deposition Polymerization of Carbazole Thin Films (2010)

With the aim of controlling the interface between an inorganic electrode and an organic layer, a surface-initiated vapor deposition polymerization method was employed to prepare carbazole polymer thin films that are chemically bound to an indium–tin oxide (ITO) surface. A self-assembled monolayer (SAM) that has an azo initiator as a terminal group was prepared on an ITO surface, on which carbazole acrylate monomers were evaporated under ultraviolet (UV) irradiation. The surface morphological characteristics of the films prepared with/without UV irradiation and with/without the SAM were compared. It was found that the UV irradiation leads to the polymerization of carbazole monomers irrespective of the type of substrate used. On the other hand, the surface morphological characteristics were largely dependent on the existence of the SAM. Uniform and smooth polymer thin films were obtained only when the monomers were evaporated on the SAM-modified surface under UV irradiation. A comparison of film growth characteristics on a UV–ozone-treated ITO surface suggested that the formation of uniform films was made possible not by the modification of surface energy but by the growth of the polymers chemically bound to the substrate surface.
Substitutive chlorination of naphthalene esters (1968)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSubstitutive chlorination of naphthalene estersGrover L. Farrar and Phillip W. StormsCite this: J. Chem. Eng. Data 1968, 13, 2, 284–286Publication Date (Print):April 1, 1968Publication History Published online1 May 2002Published inissue 1 April 1968https://pubs.acs.org/doi/10.1021/je60037a047https://doi.org/10.1021/je60037a047research-articleACS PublicationsRequest reuse permissionsArticle Views75Altmetric-Citations3LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Electrical response of the Summit‐Greenland ice core to ammonium, sulphuric acid, and hydrochloric acid (1994)

Electrical and chemical analysis of the GRIP ice core from Summit in central Greenland confirms that the ECM current is controlled solely by acids in the ice, though there could be different responses for different acids. The dielectric conductivity is dependent on strong acid, on sea salt chloride, and also on ammonium concentrations in the ice. The response to NH 4 + is similar to that of sea salt chloride, as they both conduct only at AC frequencies, but NH 4 + is approximately twice as conductive per mole. The response to the strong acids shows results consistent with earlier work, with similar responses throughout the length of the core. It seems as if all the thousands of electrical peaks in the GRIP core may be explained by the response to just three chemical species: acidity, ammonium salts, and a third component which is probably chloride.
UTILISATION ÉNERGÉTIQUE DE L'ORGE, DU BLÉ, DU MAÏS ET DU SORGHO PAR L'AGNEAU EN CROISSANCE (1970)

L'tude de l'utilisation nergtique de 4 Crales, effectue sur 86 agneaux en croissance par estimation de la composition corporelle, indique que la valeur nergtique nette du mas est suprieure celle de l'orge, du sorgho et du bl ; la valeur nergtique nette du bl est elle-mme suprieure celle de l'orge. Pour des agneaux ayant eu une vitesse de croissance modre (de 1 6 3 175 g/j) la protinogense a t par rapport la lipogense plus importante avec le mas qu'avec les trois autres crales.
Synthesis of hydroxy sodalite from coal fly ash using waste industrial brine solution (2011)

The effect of using industrial waste brine solution instead of ultra pure water was investigated during the synthesis of zeolites using three South African coal fly ashes as Si feedstock. The high halide brine was obtained from the retentate effluent of a reverse osmosis mine water treatment plant. Synthesis conditions applied were; ageing of fly ash was at 47 ° C for 48 hours, and while the hydrothermal treatment temperature was set at 140 ° C for 48 hours. The use of brine as a solvent resulted in the formation of hydroxy sodalite zeolite although unconverted mullite and hematite from the fly ash feedstock was also found in the synthesis product.
Vasopressin-secreting neurons derived from human embryonic stem cells through specific induction of dorsal hypothalamic progenitors (2018)

Arginine-vasopressin (AVP) neurons exist in the hypothalamus, a major region of the diencephalon, and play an essential role in water balance. Here, we established the differentiation method for AVP-secreting neurons from human embryonic stem cells (hESCs) by recapitulating in vitro the in vivo embryonic developmental processes of AVP neurons. At first, the differentiation efficiency was improved. That was achieved through the optimization of the culture condition for obtaining dorsal hypothalamic progenitors. Secondly, the induced AVP neurons were identified by immunohistochemistry and these neurons secreted AVP after potassium chloride stimulation. Additionally, other hypothalamic neuropeptides were also detected, such as oxytocin, corticotropin-releasing hormone, thyrotropin-releasing hormone, pro-opiomelanocortin, agouti-related peptide, orexin, and melanin-concentrating hormone. This is the first report describing the generation of secretory AVP neurons derived from hESCs. This method will be applicable to research using disease models and, potentially, for regenerative medicine of the hypothalamus.
Biochemical evidence linking the GIX thymocyte surface antigen to the gp69/71 envelope glycoprotein of murine leukemia virus. (1975)

It is known that the thymocyte surface antigen GIX is found in some strains of mice and not others, and that its expression in mice of strain 129, in which most extensive genetic studies have been made, is controlled by two unlinked cellular chromosomal loci. We have now isolated a protein with a mol wt of approximately 70,000 daltons from the surface of thymocytes from 129 mice, which have antigenic and biochemical properties characteristic of the gp69/71 envelope component of murine leukemia virus. Our evidence is compatible with the conclusion that it carries the GIX antigen.
Theory of Rolling for the Range of Mixed Friction : Part 2, A Method of Calculation for the Rolling with Front and Back Tensions (1978)

In our previous paper, a theoretical solution applicable to plate or strip rolling process without tension has been derived from Orowan's fundamental equations by making some mathematical approximations to them. This solution is effective for explaining the rolling characteristics especially in the range of mixed friction where the regions of slipping friction and sticking friction coexist on the contact arc with roll. In this paper, we extend this solution to the case where front and back tensions are applied, and theoretically examine the effect of tension on rolling phenomena under various states of friction, particularly in the range of mixed friction.
Das Valenzkraftfeld des Dimethylnitrosamins (1974)

Abstract Das Valenzkraftfeld des Dimethylnitrosamins wurde mit den Schwingungsfrequenzen der sieben isotopen Moleküle (CH 3 ) 2 NNO, (CD 3 ) 2 NNO, (CH 3 ) 2 NN 18 O, (CH 3 ) 2 N 15 NO, (CH 3 ) 2 15 NNO, CD 3 (CH 3 )NNO und CH 3 )NNO bestimmt. Die Normalschwingungen und die Verteilung der potentiellen Energie wurden berechnet. Die Kraftkonstanten zeigen eine starke Konjugation zwischen NN‐ und NO‐Bindung an. Die für die wichtigeren Abstände berechneten mittleren Schwingungsamplituden stimmen gut mit den Ergebnissen einer Elektronenbeugungs‐Untersuchung überein.
Modelling of Current Percolation Channels in Emerging Resistive Switching Elements (2012)

Metallic oxides encased within Metal-Insulator-Metal (MIM) structures can demonstrate both unipolar and bipolar switching mechanisms, rendering them the capability to exhibit a multitude of resistive states and ultimately function as memory elements. Identifying the vital physical mechanisms behind resistive switching can enable these devices to be utilized more efficiently, reliably and in the long-term. In this paper, we present a new approach for analysing resistive switching by modelling the active core of two terminal devices as 2D and 3D grid circuit breaker networks. This model is employed to demonstrate that substantial resistive switching can only be supported by the formation of continuous current percolation channels, while multi-state capacity is ascribed to the establishment and annihilation of multiple channels.
Restriction map construction using a ‘complete sentences compatibility’ algorithm (1988)

We have developed a new algorithm 'Complete sentences compatibility' (CSC) which uses single and double digestion fragments to rapidly determine restriction maps of circular DNA. From possible combinations of fragments of each simple digestion, which we call 'sentences of decomposition', we construct a restriction map which combines the sentences while taking into account compatibility rules. The algorithm can also deal with experimental errors of fragment weight and can suggest solutions that account for non-readable bands (fragments of zero length or multiple bands) on the gel. Because experiments using pairs of restrictive enzymes often result in multiple solutions, a complementary algorithm tries to reduce the number of proposed solutions by establishing consensus maps. The restriction map construction algorithm was tested on real cases, some containing more than fifteen fragments. Execution times range from 1-10 s on an IBM PC compatible microcomputer.
Mätstudie av några avgassystems strömningsakustiska egenskaper : en mätrapport utförd åt Volvo PV (2000)

Matstudie av nagra avgassystems stromningsakustiska egenskaper : en matrapport utford at Volvo PV
ChemInform Abstract: STUDY OF THE SYNTHESIS OF KETONES BY ALKYLATION AND GRIGNARD REACTION. SYNTHESIS OF STERICALLY VERY HINDERED KETONES (1981)

Abstract Ketone R‐CO‐R′ (die längste C‐Kette in R bzw. R′ besteht dabei aus maximal 3 C‐Atomen) werden bezüglich ihrer Herstellung durch Alkylierung von Ketonen oder durch Um‐ 55 setzung von Säurechloriden mit Grignardreagentien graphentheoretisch behandelt.
CC Bond‐Forming Reactions (2006)

This chapter contains sections titled: General Transition Metal-Mediated Vinylations, Arylations, and Alkylations The Suzuki Coupling The Heck Reaction The Sonogashira Coupling The Stille Coupling Remarks on Pd-mediated Couplings on a Polymeric Support Experimental Approach Materials and Methods Miscellaneous Aryl-Aryl Couplings Ullmann/Wurz Coupling on a Polymeric Support Intermolecular Alkyl-Alkyl Coupling Negishi Couplings Alkene Metathesis Reactions Ring-Closing Metathesis (RCM) Reactions Cross-Metathesis (CM) Reactions Cycloaddition Reactions on a Polymeric Support C1 Fragments (Additions of Carbenes to Alkenes) Electron-Deficient C2 Fragments (Cycloadditions Involving Azomethines, Nitrones, Nitrile Oxides, and Dienes) Electron-Rich C2 Fragments ([2 + 1], [2 + 2], [2 + 3], [2 + 4]-Cycloadditions, Additions with Nitrile Imines, Nitrile Oxides, and Chalcones) CX Fragment on Solid Support CCX Fragments on the Polymeric Support CXC Fragment CXY-Fragment (Nitrile Oxide on Solid Phase) CCCC Fragments on Solid Phase CCCX Fragments on Solid Support CCXC Fragment on Solid Support (Grieco Three-Component Condensation) CXXC Fragment on Solid Support CCXX Fragment on Solid Support ([4 + 1]-Cycloaddition) Cycloadditions Involving Larger Support-Bound Fragments: Intramolecular Hetero Diels-Alder Pauson-Khand and Nicolas Reaction C-Nitroalkene Additions Multicomponent Reactions (MCRs) Ugi Four-Component Reaction Ugi Reaction with Solid-Supported Isonitriles Ugi reaction with Solid-Supported Amines Ugi Reaction with Solid-Supported Carboxylic Acid Derivatization of Boronic Acids Other MCRs Using Isonitriles Petasis (Borono-Mannich) Condensation Imidazo[1,2-α]pyridines Biginelli Dihydropyrimidines Synthesis Thiophene Synthesis Tetrahydropyridones Cyclization Cleavage Electrophiles Bound to the Polymeric Support Reactions with Organyls of Zn, Mg, Li Reactions Involving Grignard Reagents, Organolithium, and Organozinc Reagents Reactions with Water-Sensitive Reagents such as Grignard Reagents, Lithium Alkyls, or Zinc Organyls [375] on Solid Phases Indium-Mediated Allylation of Support-Bound Aldehydes Sn/Pd-Mediated C-Allylation of Solid-Phase-Bound Aldehydes Metal-free Alkylations by Acyl Halides on Polymeric Supports Nucleophilic Aromatic Substitution with C-Nucleophiles Pyridine-N-Oxides Trapping Phosphorus Ylides with a Ketone Bound to the Solid Phase Michael Acceptor on Solid Phase (Route to 3,4,6-Trisubstituted Pyrid-2-ones) Solid phase N-Acyliminium Ions, Imines and Glyoxylate Chemistry Solid-Supported Imines and Glyoxylate Solid-Phase Pictet-Spengler Reactions Solid-Phase Baylis-Hillman Reaction Solid-Phase Fischer Indole Synthesis Solid-Phase Madelung Indole Synthesis Boron Enolates with Support-Bound Aldehydes Summary of Solid-Supported Electrophiles Generation of Carbanions on Solid Supports Transition Metal-Mediated Carbanion Equivalent Formations Lewis Acid-Mediated Electrophilic Substitutions Generation of Stabilized Carbanions Under Basic Conditions Experimental Approach Stereoselective Alkylations on a Chiral Solid Phase Solid-Phase Radical Reactions Outlook References
Catalytic activity of the electron donor–acceptor complex of polynaphthoquinone with potassium (1972)

High catalytic activities of the electron donoracceptor complex of polynaphthoquinone with potassium are reported for H2–D2 exchange, the synthesis of ammonia, hydrogen exchange of propene with deuterium, hydrogenation of propene, and isomerization of butene.
Analysis of triglyceride synthesis unveils a green algal soluble diacylglycerol acyltransferase and provides clues to potential enzymatic components of the chloroplast pathway (2017)

Our analysis contributes to advance in the knowledge of complex superfamilies involved in lipid metabolism and provides clues to possible enzymatic players of chloroplast TAG synthesis.
ChemInform Abstract: Efficient Syntheses of a Novel 5‐Thia‐1‐azacycl[3.3.2]azine Ring System and 3H‐1,4‐Diazacycl[3.3.2]azine Derivatives. (2000)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Active Variable Reactance Rectifier—A New Approach to Compensating for Coupling Variations in Wireless Power Transfer Systems (2019)

This article introduces a new approach to compensate for coupling variations in wireless power transfer (WPT) systems by utilizing an active variable reactance (AVR) rectifier. The AVR rectifier operates at a fixed frequency and incorporates a power-splitting resonant network. By controlling the ratio of the split powers in its branches, the AVR rectifier continuously compensates for large misalignments and distance variations between couplers, while maintaining full power transfer. A comprehensive methodology is presented that maximizes the tolerable range of misalignments in an AVR-rectifier-enabled capacitive WPT system while meeting efficiency targets. The proposed approach is validated using a 13.56-MHz, 300-W, 12-cm nominal air-gap prototype capacitive WPT system, which incorporates an AVR rectifier and can be scaled up in power for dynamic electric vehicle (EV) charging applications. The prototype system maintains full power transfer for up to 45% lateral misalignment in the coupler and up to 45% increase in the vehicle's road clearance. In a dynamic EV charging scenario, the AVR-rectifier-enabled system transfers 80% more energy during a single pass of the vehicle over the charging pad, as compared to a system without the AVR rectifier. The measured performance of the prototype system is in good agreement with predictions.