gebhart/patrepeval huggingface dataset:
ChemInform Abstract: SYNTHESIS AND PROPERTIES OF N‐(ALKYL‐ AND ARYLSULFINYL)PHTHALIMIDES, A NEW CLASS OF SULFINYL‐TRANSFER REAGENTS (1974)

Abstract m‐Chlorperbenzoesäure oxidiert die Alkylmercapto‐phthalimide (I) zu den‐ Sulfmyl= Verbindungen (II); aus dem Disulfid (III) entsteht analog das Mono‐sulfoxid (IV).
Reaction of N-benzoyl amino acids with oxalyl chloride: a facile route to 4-substituted 2-phenyloxazole-5-carboxylates (1995)

T. Cynkowski, G. Cynkowska, P. Ashton and P. A. Crooks, J. Chem. Soc., Chem. Commun., 1995, 2335 DOI: 10.1039/C39950002335
Upwelling Radiance at 976 nm Measured from Space Using a CCD Camera (2015)

The Optical Payload for Lasercomm Science (OPALS) Flight System on-board the International Space Station uses a charge coupled device (CCD) camera for receiving a beacon laser from Earth. Relative measurements of the background contributed by upwelling radiance under diverse illumination conditions and varying terrain is presented. In some cases clouds in the field-of-view allowed a comparison of terrestrial and cloud-top upwelling radiance. In this paper we will report these measurements and examine the extent of agreement with atmospheric model predictions.
Adsorption of Acridine Orange at a C<sub>8,18</sub>/Water/Acetonitrile Interface (2007)

Fully atomistic simulations are used to characterize the molecular dynamics (MD) of acridine orange (3,6-dimethylaminoacridine) at a chromatographic interface. Multiple 1 ns MD simulations were performed for acridine orange at the interface between three different acetonitrile/water mixtures (0/100, 20/80, and 50/50) with C8 and C18 alkyl chains. The diffusion coefficient, D, of acridine orange in pure solvent was found to be 4 times smaller at the water/C18 interface (D = 0.022 x 10(-4) cm2/s) than in bulk water (D = 0.087 x 10(-4) cm2/s), in qualitative agreement with experiment. Rotational reorientation times were 20 and 700 ps, which also agree favorably with the measured time scales of 130 and 740 ps. Contrary to experiment, the simulations found that for increasing surface coverage, the diffusion coefficient for acridine decreased. Detailed analysis of the solvent structure showed that the transport properties of acridine were primarily governed by the solvent distribution above the functionalized surface. The solvent structure, in turn, was largely determined by the surface consisting of the silica layer, the alkyl chains, and their functionalization.
Effect of quercetin conjugates on vascular permeability and expression of adhesion molecules (2004)

Quercetin and its glucosides exist in plant foods and are recovered in human plasma as glucuronide and sulfate conjugates. Quercetin and its conjugates show antioxidant activity in model experiments. It remains obscure, however, whether these conjugates retain these biological functions in vivo. We investigated the interaction of quercetin conjugates with lipid bilayers using liposome systems. Less quercetin conjugate was incorporated into liposomes than quercetin aglycone. We also studied the vascular permeability of quercetin-3-glucuronide using cell culture inserts. Incubation of human aortic endothelial cells (HAECs) with IL-1alpha resulted in increased permeability of quercetin-3-glucuronide. Furthermore, quercetin-3-glucuronide showed no suppressive effect on TNF-alpha-induced cell expression of intercellular adhesion molecule-1 (ICAM-1) on HAECs. These observations suggest that circulating conjugates of quercetin pass through the endothelium to reach vascular smooth muscle cells and exert their biological effects in the blood vessels during inflammation followed by deconjugation of the conjugates.
Development of real-time control system for single-wheeled inverted pendulum platform (2011)

Wheeled inverted pendulum has been a standard benchmark in control research. It normally has two wheels to limit the unstable mode in the longitudinal direction. In this paper, wheeled inverted pendulum with only one wheel is investigated. The dynamics model is derived based on Lagrange-Euler formulation. Linear controller is then designed for balancing task and straight-line tracking task. Simulation in MATLAB is also performed to confirm the linear controller performance. Finally, a simple prototype is developed which confirms simulation results and sheds light on the many practical problems and limitations, not observable from simulation: sensor noise, sampling rate, gear backlash, static and dynamic friction, mechanical vibration, time delay and actuator saturation.
A prototype hardware cognitive radio for communications in an interference environment (2009)

The application of cognitive radio (CR) techniques to enable efficient utilization of spectrum is an area of growing interest. In this paper we describe the design and the functionality of a hardware CR prototype board aimed at providing a low cost mass production solution for networked cognitive radios. The CR prototype enables the development and investigation of spectrally efficient waveforms tailored for operation in the military 225-400 MHz VHF/UHF bands, in the presence of interference.
Stable fiber-source gyroscopes (1990)

We describe two new configurations of fiber gyroscopes that use superfluorescent fiber laser sources. In the first configuration we introduce a backward-pumping technique that achieves an order-of-magnitude increase in the power that can be launched into the gyroscope without instabilities. In the second configuration we employ the optical gain of the superfluorescent fiber laser source to amplify the signal returned from the gyroscope, obtaining an additional three-orders-of-magnitude increase in the optical power incident upon the detector, with an implication for simplification of the electronics. In both configurations, source beat-noise-limited rotation sensitivity is achieved.
Anti-VP6 IgG antibodies against group A and group C rotaviruses in South India (2009)

In an epidemiological survey from South India, 936 serum samples were tested for IgG against recombinant baculovirus-expressed VP6 proteins from human group A and group C rotaviruses. The overall seroprevalence for group A was 100% and for group C was 25.32% (95% CI 22.64-28.21). The lowest seroprevalence for group C was in children aged <10 years (16.79%). An age-related rise in seroprevalence in group C, but not group A, suggests different patterns of exposure. Seroprevalence was similar in rural and urban subjects, unlike the higher prevalence in rural subjects in studies elsewhere.
Stable and Efficient Generation of High Repetition Rate ($>$160 GHz) Subpicosecond Optical Pulses (2011)

A stable optical beat-signal with frequency >; 160 GHz is produced by injection-locking two narrow-linewidth semiconductor lasers emitting at frequencies spaced by the beat-frequency to a low-jitter 10-GHz optical comb. The generated beat-signal with broadband noise suppression of >; 75 dB is temporally compressed by factors of up to four in a high stimulated Brillouin scattering threshold aluminosilicate highly nonlinear fiber. The generated subpicosecond pulses have a root mean square (rms) timing jitter below 150 fs measured over 1 s.
nEASE: a method for gene ontology subclassification of high-throughput gene expression data (2012)

Supplementary data are available at Bioinformatics online.
Study on Weldability of Dispersion Hardening Alloy (Report 4) (1974)

The weldability of dispersion hardening alloys must be made clear in order to use them in various industries. Especially, on the point of practical use, it is very important to increase the joint efficiency.So, in this report, the disappearance of voids and the behavior of ThO2 particles at the bonding interface were discussed as the first step of applying the solid state bonding to the dispersion hardening alloys.The main results obtained are summarized as follows;(1) The disappearance of voids is mainly accelerated by the local creep deformation. The mechanical deformation at the bonding interface is an important process for the solid state bonding.(2) The disappearance phenomena of voids and the behavior of ThO2 particles at the bonding interface were metallurgically investigated. The authors indicated the temperature-time region which was useful to etermine the solid state bonding conditions of TD nickel.
The incidence of virulence factors in mesophilic<i>Aeromonas</i>species isolated from farm animals and their environment (1990)

Sixty-one isolates of Aeromonas spp. from the faeces of pigs, cows and a variety of associated environmental sources were examined for the characteristics that are reputed to have roles in pathogenicity. Most isolates of Aeromonas hydrophila were cytotoxic (96.4%) and were capable of producing cell elongation factor (75%) and haemagglutinins (67.9%). In contrast few of the Aeromonas caviae isolates produced these three markers (13.6%, 27.3% and 36.4% respectively). In general, Aeromonas sobria occupied an intermediate position (36.4%, 27.3% and 54.5%), but they did produce the highest mean invasion index for HEp-2 cells. Statistical analysis revealed significant associations between the carriage of these factors and it was clear that many isolates of aeromonads from water and animals possessed the full battery of putative virulence factors.
DTI Detection of Longitudinal WM Abnormalities Due to Accumulated Head Impacts (2015)

Longitudinal evaluation using diffusion-weighted imaging and collision event monitoring was performed on high school athletes who participate in American football. Observed changes in white matter health were suggestive of injury and found to be correlated with accumulation of head collision events during practices and games.
Influence of Cytokines on the Growth Kinetics and Immunophenotype of Daughter Cells Resulting From the First Division of Single CD34+Thy-1+lin− Cells (1998)

There is a need to determine whether culture conditions may exist for ex vivo expansion of hematopoeitic stem cells (HSC), which favor solely proliferative self-renewal of HSC as opposed to proliferation with differentiation. Using single cells, we studied the effects of individual and combinations of cytokines in serum-free medium on the kinetics of the first cell doubling and the resulting phenotype of each of individual daughter cell. CD34+Thy-1+lin−cells were plated 1 cell per well in Terasaki plates in serum-free medium containing cytokines. Each well containing a single cell was monitored daily over 7 days for maintenance, division, or death. When division occurred in an individual well, the phenotype of the daughter cells was determined by staining with anti-CD34 fluorescein isothiocyanate (FITC)- and phycoerythrin (PE)-conjugated lineage specific antibodies. The cumulative percent of wells with an undivided single cell, wells in which the cell had divided, and wells in which the cell had died were scored. The number of doublets with conserved phenotype (CD34+lin−) was compared to those wells with one or more differentiated daughter cells (CD34+lin+). Over 7 days, cells cultured in single factors showed that between 13% (interleukin-6 [IL-6]) and 29% (thrombopoietin [TPO]) of the cells were undivided, between 13% (IL-1) and 35% (TPO) of the cells doubled, and between 35% (TPO) and greater than 60% (IL-11, IL-1, or hepatocyte growth factor [HGF]) died. When combinations of cytokines were used over 7 days, between 5% (FLT-3 ligand [FLT-3L], stem cell factor [SCF], IL-3, IL-6, granulocyte colony-stimulating factor [G-CSF], β nerve growth factor [βNGF]) and 22% (FLT-3L + HGF) of the cells remained undivided, between 15% (HGF, IL-1, IL-11, G-CSF) and 68% (SCF + TPO) of the cells had doubled and between 27% (FLT-3L + TPO) and 70% (HGF, IL-1, IL-11, G-CSF) died. The combination of FLT-3L + TPO induced the highest total percent (64.6%) of cells with conserved phenotype (percent conserved doublets + percent with 1 cell conserved), followed by SCF + TPO, (50%) and the combination of FLT-3L, SCF, IL-3, IL-6, G-CSF, βNGF (53%). These combinations also produced the highest yield of cells with conserved phenotype after one division (FLT-3L + TPO − 81 cells/100 initial cells, SCF + TPO − 68 cells/100 initial cells) (P = .01). Observation of the time of the initial cell division and phenotype of the daughter cells allowed us to identify candidate combinations of cytokines that promote maintenance of lin− cells (TPO), or recruit the primitive cells to divide and undergo phenotypic self-renewal (FLT-3L + TPO, SCF + TPO).
ChemInform Abstract: NEW SYNTHESIS OF SUBSTITUTED DISELENADITHIAFULVALENES (DSDTF) AND TETRASELENAFULVALENES (TSF) (1977)

Abstract 2‐Chl0rcyclopentanon (I) und Tetramethylthio‐ (IIa) und Tetramethylselenoharnstoff (IIb) reagieren bei Raumtemperatur zu den Perchloraten (III), die mit HzSe zu den Selenoverbindungen (IV) gespalten werden.
PROGNOSTIC SIGNIFICANCE OF A SINGLE NUCLEOTIDE POLYMORPHISM IN THE MMP-1 PROMOTER IN CHONDROSARCOMA (2005)

Introduction and Aims: Matrix metalloproteinases can contribute to the processes of tumor invasion and metastasis. One proposed mechanism that could augment MMP-1 expression in individual patients is the existence of an Ets transcription factor-binding site in the MMP-1 promoter sequence. The aim of our study was to identify the prevalence of this single nucleotide polymorphism in chondrosarcoma patients and investigate its impact on disease outcome. Method: Sixty-seven chondrosarcoma specimens were selected from an established tumor bank. DNA was extracted, amplified with polymerase chain reaction, and sequenced to determine the proportion of genotypes demonstrating the presence (GG) or absence (G) of the SNP at the base pair of interest. The presence of the Ets binding site was correlated with disease-free survival. Results: Eighteen (27%) samples were G/G homozygous for absence of the Ets site, 34 (51%) were G/GG heterozygous for the SNP, and 15 (22%) were GG/GG homozygous for the SNP. The five-year overall survival rate for patients with the G/G homozygote was 78%, compared with 80% and 84% in patients with the G/GG heterozygotes and GG/GG homozygotes, respectively (p=0.5527). The disease-free survival rate of patients with the G/G genotype were 34%, compared with 74% and 100% in patients with the G/GG and GG/GG genotypes, respectively (p=0.0365). Conclusion: The disease-free survival in patients having a GG allele was statistically better than the G allele. The observed correlation between the presence of the Ets binding site and better prognosis suggests a down-regulation of MMP-1 expression.
Protein nutrition of the neonate (2000)

The period of growth and development between birth and weaning is crucial for the long-term well-being of the organism. Protein deposition is very rapid, is achieved with a high nutritional efficiency, and is accompanied by marked differences in the growth rates of individual tissues and a series of maturational processes. These important aspects of development occur while the neonate is consuming a single and highly-specific food source, milk. Surprisingly, although there is a clear relationship between the nutrient density of milk and the growth rate of its recipient, this relationship does not apply to the overall amino acid composition of mixed milk proteins. Some amino acids, notably glycine and arginine, are supplied in milk in quantities that are much less than the needs of the neonate. The milk-fed neonate is therefore capable of carrying out a tightly-regulated transfer of N from amino acids in excess to those that are deficient. The rapid growth of the neonate is supported by a high rate of tissue protein synthesis. This process appears to be activated by the consumption of the first meals of colostrum. Recent research has identified that skeletal muscle and the brain are specifically responsive to an unidentified factor in colostrum. Following the initial anabolic response the rate of protein synthesis in some tissues, notably muscle, falls from birth to weaning. This decrease reflects a progressively smaller anabolic response to nutrient intake, which not only involves an overall fall in the capacity for protein synthesis, but also in responses to insulin and amino acids. The study of growth and protein metabolism, and their regulation in the neonate is not only important for pediatrics, but may provide important pointers to more general aspects of regulation that could be applied to the nutrition of the mature animal.
Beta mixture models and the application to image classification (2009)

Statistical pattern recognition is one of the most studied and applied approaches in the area of pattern recognition. Mixture modelling of densities is an efficient statistical pattern recognition method for continuous data. We propose a classifier based on the beta mixture models for strictly bounded and asymmetrically distributed data. Due to the property of the mixture modelling, the statistical dependence in a multi-dimensional variable is captured, even with the conditional independence assumption in each mixture component. A synthetic example and the USPS handwriting digit data was used to verify the effectiveness of this approach. Compared to the conventional Gaussian mixture models (GMM), the beta mixture models has a better performance on data which has strictly bounded value and asymmetric distribution. The performance of beta mixture models is about equivalent to that of GMM applied to data transformed via a strictly increasing link function.
Patient-reported frequency, awareness and patient-physician communication of hypoglycaemia in Belgium (2014)

Hypoglycaemic events and unawareness of these events are common in Belgian insulin-treated diabetes patients. Patients often fail to report hypoglycaemic events to their physician and many physicians do not inquire about hypoglycaemia, meaning the current burden of hypoglycaemic events may be underestimated.
Correlation of Histologic and Clinical Images to Determine the Diagnostic Value of Fluorescein Angiography for Studying Retinal Capillary Detail (2010)

FFA provides incomplete morphologic information about the superficial capillary network and even less information about the deep capillary network. Caution should, therefore, be exercised when using FFA data to extrapolate information about microvascular histopathologic processes. The usefulness of newer technology for studying retinal capillary detail should be investigated.
Minicircle DNA Immobilized in Bacterial Ghosts: In vivo Production of Safe Non-Viral DNA Delivery Vehicles (2004)

DNA as an active agent is among the most promising technologies for vaccination and therapy. However, plasmid backbone sequences needed for the production of pDNA in bacteria are dispensable, reduce the efficiency of the DNA agent and, most importantly, represent a biological safety risk. In this report we describe a novel technique where a site-specific recombination system based on the ParA resolvase was applied to a self-immobilizing plasmid system (SIP). In addition, this system was combined with the protein E-specific lysis technology to produce non-living bacterial carrier vehicles loaded with minicircle DNA. The in vivo recombination process completely divided an origin plasmid into a minicircle and a miniplasmid. The replicative miniplasmid containing the origin of replication and the antibiotic resistance gene was lost during the subsequently induced PhiX174 gene E-mediated lysis process, which results in bacterial ghosts. The minicircle DNA was retained in these empty bacterial cell envelopes during the lysis process via the specific interaction of a membrane anchored protein with the minicircle DNA. Using this novel platform technology, a DNA delivery vehicle--consisting of a safe bacterial carrier with known adjuvant properties and minicircle DNA with an optimized safety profile--can be produced in vivo in a continuous process. Furthermore, this study provides the basis for the development of an efficient in vitro minicircle purification process.
Dimethyloxosulfonium 2-(methylamino)benzoylmethylide. New stable ylide and its use in heterocyclic syntheses (1968)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTDimethyloxosulfonium 2-(methylamino)benzoylmethylide. New stable ylide and its use in heterocyclic synthesesA. M. Van Leusen and Edward Curtis TaylorCite this: J. Org. Chem. 1968, 33, 1, 66–70Publication Date (Print):January 1, 1968Publication History Published online1 May 2002Published inissue 1 January 1968https://pubs.acs.org/doi/10.1021/jo01265a013https://doi.org/10.1021/jo01265a013research-articleACS PublicationsRequest reuse permissionsArticle Views160Altmetric-Citations7LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Medical Presentations of Choriocarcinoma (1971)

Choriocarcinoma commonly presents with symptoms resulting from metastases in the lungs, central nervous system, or alimentary tract. This tumour may occur without any gynaecological symptoms and when pelvic examination and uterine curettage show no abnormality. Several years may elapse between the antecedent pregnancy and presentation with metastatic disease. The ability to eradicate these tumours with present chemotherapeutic methods depends on detecting their presence as soon as possible after the antecedent pregnancy.Wider recognition of the varied manifestations of metastatic choriocarcinoma and greater use of tests for chorionic gonadotrophin should result in earlier diagnosis and an improved prognosis in these patients. In particular, such tests should be made in patients with unexplained intracranial haemorrhage, progressive dyspnoea, and gastrointestinal haemorrhage.
Sulfur reduction potential of the bituminous coals of Pennsylvania. [Extensive washability data for PA coals] (1982)

This report presents the results of a washability study of 205 raw coal channel samples with an emphasis on sulfur reduction. These raw coals contained on the average 14.8% ash, 1.73% pyritic sulfur, 2.52% total sulfur, 12,812 Btu/lb, and 4.0 pounds of SO/sub 2/ emissions per million Btu, on a moisture free basis. The complete washability data and ultimate-proximate data are presented for these samples. Each individual washability analysis is presented in Appendix A. Statistical evaluations of the washability data and ultimate-proximate analyses are presented on a coalbed basis, whenever there are six or more samples from a given coalbed. An additional evaluation is included showing the composite data interpolated at Btu recovery levels of 50, 60, 70, 80, 90, and 100%. Graphical representations are given for various coal characteristics of both raw and washed coal fractions for all coalbeds with six or more samples. For coalbeds with 20 or more samples, goodness-of-fit tests were made comparing SO/sub 2/ distributions with both normal and log-normal distributions. Confidence intervals and tolerance limits are calculated and illustrated for the SO/sub 2/ emission values as a function of specific gravity for these coalbeds. In general, ash reduction, pyritic sulfur reduction, total sulfur reduction,more » and SO/sub 2/ emissions reduction increase as the coal is crushed to smaller top sizes and as the coal is cleaned at lower specific gravities. This report presents the reduction curves for the ten major coalbeds in Pennsylvania's Main Bituminous Coalfield.« less