gebhart/patrepeval huggingface dataset:
Reduction in Alternative Complement Pathway Mediated C3 Conversion following Burn Injury (1981)

Studies were performed to further investigate an abnormality of the alternative complement pathway associated with burn injury. C3 conversion by inulin and cobra venom factor was measured in serial serum samples from 18 burned patients and in the sera from 25 normal controls. C3 conversion by both activating substances in the patients' sera was significantly decreased during 50 days postburn in comparison to C3 conversion in the normal sera. The most marked reduction in C3 conversion occurred in patients with large full-thickness injuries and infectious complications. However, the abnormality was not more severe in patients with pneumonia and bacteremia in comparison to patients with bacteremia only. It was also not predictive of fatal outcome resulting from infectious complications. Preliminary evidence was presented to suggest that the abnormality is caused by a serum inhibitor, which has an affinity for cellulose and/or is inactivated by it.
A review of properties and treatment of oil sands tailings (1992)

The hot water process used to extract bitumen from the oil sands in northern Alberta produce an alkaline tailings stream containing sand, clays, residual bitumen, and small amounts of soluble organic compounds. The suspension formed by the fine clay minerals has proven to be resistant to consolidation, leaving a growing pool of persistent sludge in large tailings ponds. An introduction is provided to the literature that exists in the area of oil sand tailings characterization and treatment. Studies on the chemical, physical, and microbiological makeup of oil sands tailings and the tailings ponds are described, including settling and consolidation behavior of solids in tailings ponds and various theories as to why tailings pond sludge is so resistant to consolidation. Studies undertaken to reduce the tailings problem are reviewed, including investigation of reclamation methods for the mine site, and chemical, physical, geotechnical and biotechnical approaches to tailings treatment. Finally, there is a brief discussion of tailings problems in other industries and the methods used to try to alleviate those problems. 275 refs., 5 figs., 12 tabs.
Displacement measurement using a focusing chromatic modulator (1990)

A novel, optical-fibre-based, displacement sensing system is described and its properties and behaviour investigated experimentally and theoretically. The system utilises the chromatic modulation principle in conjunction with a spherical modulator element which economically combines both modulating and focusing functions. A computer design package based upon a two-dimensional ray model is used to illustrate the behaviour of the sensing element and to establish optimised sensor element designs. The system is shown to offer a number of advantages which include simplicity and in-built insensitivity to variations in light intensity. A resolution of 1 in 104 is shown to be achievable. No quadrature referencing is needed for direction discrimination.
HARVEY: THE SCENE OF HIS LAST YEARS AND HOURS (1960)

IT has traditionally been held that William Harvey died in his brother Eliab's house in Roehampton but there has hitherto been no really definite evidence on this point. The present paper results from an attempt to discover more about the connection of the Harvey family with the one-time village of Roehampton and to identify the exact location of the house in which the great physiologist died.
Elliptic Curve-Based Certificateless Signatures for Identity-Based Encryption (ECCSI) (2012)

Many signature schemes currently in use rely on certificates for
authentication of identity. In Identifier based cryptography, this
adds unnecessary overhead and administration. The ECCSI signature
scheme described in this document is certificate-less. This scheme has
the additional advantages of low bandwidth and low computational
requirements.
A Relationship between Colour and Structure for Simple Nitro Dyes (1967)

The long‐wavelength bands in the spectra of nitrobenzenes containing one or two strong electron‐donor groups are correlated with the 260‐ or 297‐mμ bands (or both) of nitrobenzene. The shift resulting from the introduction of two electron‐donor groups into nitrobenzene is shown to be equal to the sum of those resulting from analogous monosubstitution. Correlations of the longest wavelength band in the respective spectra of nitrobenzenes containing electron‐donor groups should thus allow for the possibility of these bands having different origins in different isomers.
A Great Improvement of the Enantioselectivity of Lipase-Catalyzed Hydrolysis and Esterification Using Co-Solvents as an Additive (2008)

Abstract Addition of co-solvents such as tetrahydrofuran resulted in a great improvement of the enantioselectivity of lipase-catalyzed hydrolysis of butyl 2-(4-substituted phenoxy)propanoates in an aqueous buffer solution. On the other hand, lipase lyophilized from an aqueous solution containing the co-solvents catalyzed highly enantioselective esterification of 2-(4-substituted phenoxy)propionic acids, 2-(4-isobutylphenyl)propionic acid (ibuprofen), and 2-(6-methoxy-2-naphthyl)propionic acid (naproxen) in an organic solvent. An increase in the E value up to two orders of magnitude was observed for some substrates. The origin of the enantioselectivity enhancement caused by the co-solvent addition was mainly attributed to a significant deceleration in the initial reaction rate for the incorrectly binding enantiomer, as compared with that for the correctly binding enantiomer. From the results of FT-IR, CD, and ESR spectra, the co-solvent addition was also found to bring about a partial destruction of the tertiary structure of lipase.
LOCNET - an experimental broadband LAN with optical switching (1984)

In a new research project of the Heinrich-Hertz-Institut Berlin (HHI) an experimental local area broadband network utilizing optical switching techniques has been designed and will be installed as a laboratory system. The local optical communication network-LOCNET-will support narrowband services like ISDN telephone and data communication with 64 kbit/s, high speed data communication up to some 4 Mbit/s (so called mediumband services) and broadband services like videophone and other services with transmission rates up to 216 Mbit/s and even more. The authors give a description of the network and its capabilities.
Engendering the Narrative Act: Old Wives' Tales in The Winter's Tale , Macbeth , and The Tempest (1998)

Framing her criticism with attacks against his masculinity—Are you a man? and What, quite unmanned in folly?—Lady Macbeth rep resents Macbeth's tearfulness as a degrading regression to the andro gyny of childhood. Her anxious allusion to women's tales in this context suggests their continuing and threatening power, and the ef feminizing attraction of the early bonds with women they signify. Paradoxically, Lady Macbeth's accusation becomes self-reflexive to the play which includes it. The air-drawn dagger which Lady Mac beth denigrates as appropriate only to women's tales places Macbeth squarely within this devalued oral tradition; so do its ghosts and its witches. Macbeth is not alone in its self-reflexive allusions to this early scene of narration. Passages within The Winter's Tale and The Tempest also invoke this oral tradition as originary to their art. Together, these allusions expose the power of childhood tales as prototypes for the fictions of the stage. From this distance in time, it is impossible to judge whether these stories were primarily authoriz'd by grandams or also composed and performed by men. The gender of their authors was, however, largely irrelevant to the reception of these tales by young children at the knees of the women who told them. Whatever the point of origin,
CD133 antibody-conjugated immunoliposomes encapsulating gemcitabine for targeting glioblastoma stem cells (2014)

CD133<sup>+</sup> cells in glioblastoma multiforme (GBM) display glioma stem cell (GSC) properties and have been considered to be the culprit in tumor recurrence, justifying the exploration of potential therapeutic modalities targeting CD133<sup>+</sup> cells. Such strategies require a drug-delivery vehicle, and increasingly, the unique properties of PEGylated liposomes are being exploited for this purpose. More advanced liposomal delivery studies have suggested conjugation of CD133 antibodies as a suitable method for targeting GSCs. For targeting studies, GSCs separated from U87 GBM cells using a magnetic bead separation method were challenged with liposomes encapsulating gemcitabine (GEM) conjugated with a CD133 monoclonal antibody (PEG-lipo-CD133-GEM). An in vitro study showed that conjugation of CD133 antibody significantly enhanced the cytotoxicity of GEM through endocytosis of CD133 surface markers overexpressed on GSCs. The anti-tumor effect of PEG-lipo-CD133-GEM was 15 times higher than that of free GEM, presumably reflecting the specific targeting of the CD133 surface marker by PEG-lipo-CD133-GEM and the enhanced stability and cytotoxicity through the PEGylated liposome formulation in xenograft models. Moreover, monitoring of body weight changes showed that the use of PEGylated liposomes significantly reduced the toxicity of GEM. Taken together, our studies demonstrate that PEG-lipo-CD133-GEM shows promise for the treatment of gliomas in vitro and in xenograft models.
The Composite Camshaft: Advanced Materials to Meet the Requirements of Today (1990)

<div class="htmlview paragraph">There is great emphasis in the automotive industry to develop innovative designs using advanced materials and techniques. Not only must these designs be creative and cost effective, they must also meet the ever increasing demands of present and future applications. One area where designers look for savings in both weight and production cost is the camshaft. Innovative design, the excellent use of a wide variety of materials and the power of computer aided engineering are all being combined to produce a lighter, more cost effective camshaft.</div> <div class="htmlview paragraph">This paper will discuss the key aspects of material, design and analysis that led to the development of the composite camshaft. It will list both the economical and physical advantages of sintered, machined, and formed components, stabilized by an engineering plastic. All of this information will show that the right combination of design, material and analysis has produced a breakthrough in the camshaft industry, opening the door for future design in other areas.</div> <div class="htmlview paragraph">SEVERAL COMPANIES are developing new types of camshafts that will be lighter, generate less noise and cost less. There are developments that involve new methods of manufacturing, using separate components that are combined to form a composite camshaft.</div> <div class="htmlview paragraph">One of these methods uses metal lobes and journals that are precisely located on a hollow metal shaft which is then expanded, either mechanically or hydraulically, locking the lobes and journals in place. Another method uses a diffusion bonding technique to weld the lobes and journals into place. A third, and very unique method utilizes an engineering plastic to bind the lobes and journals to the center shaft. The design and development of this unique method of using plastic to create what is truly a composite camshaft will be discussed.</div>
Corn proteins: chemical and physical changes during drying of grain (1975)

Changes in proteins in high-moisture corn dried at elevated temp. were investigated to determine reasons for previously reported reduced grain quality for seed, milling, and feed uses. Grain harvested at 25% moisture was dried to about 15% moisture by heating at air temp. ranging from 15° to 143°C in a forced-air dryer. Proteins were sequentially extracted from defatted grain or endosperm meals with various solvents. Amounts of proteins extracted with 0.5N NaCl were markedly reduced in meals heated to 143°C, and their electrophoretic patterns changed significantly. A smaller decrease occurred in yield of zein extracted with 70% ethanol-0.5% sodium acetate. Buffer containing 0.5% sodium dodecyl sulphate (SDS) dissolved some of the unsolubilized protein. Increased solubility in 0.5% SDS solution containing mercaptoethanol of proteins of corn dried with 143°C air indicated that intermolecular disulphide bonds are formed during heating. The number of sulphydryl groups decreased during heating of whole grain; a parallel decrease occurred in grain viability. Lysine and available lysine contents were reduced slightly by heating at the highest temp.
Dynamic stability and network constrained optimal spinning reserve allocation (2011)

This paper presents an integrated work for regulation reserve allocation considering dynamic stability and load variations. In deregulated power system, participants compete to maximize their surplus without considering system stability margin, which forces the power system to operate closer to their instability boundaries. Suitable spinning reserve amount and allocation to meet additional load demand and the corresponding power flows through transmission lines at acceptable stability margin is an important aspect for a secure power system operation following a credible contingency. The geographical localization and coordination of the available amount of spinning reserve used for regulation must be based on accurate online system state to cover the uncertainty associated with electric demand. The target is to minimize the cost of spinning reserve considering system operational constraints independent on the energy market auctions. This target is achieved by using a mixture of a modified particle swarm optimization (PSO) and artificial neural network (ANN). ANN is used to assess power system stability to shortage the computation time. The rescheduling process based on the generation companies The critical clearing time (CCT) at the critical contingency is considered as an index for transient stability. System minimum damping of oscillation (MDO) is considered as indicator for oscillatory stability. The proposed framework has been applied on a 66-bus test system.
High-power broadly tunable erbium-doped silica fibre laser (1989)

A Ti:sapphire laser at 980 nm has been used to pump a grating-tuned erbium-doped silica fibre laser. 540 mW launched pump power produces up to 270 mW tunable output near 1.55μm, with more than 250mW obtainable from 1.52 to 1.57μm.
Texture classification with tree-structured wavelet transform (2003)

Proposes a multiresolution approach based on a tree-structured wavelet transform for texture classification. The development of tree-structured wavelet transform is motivated by the observation that textures are quasi-periodic signals whose dominant frequencies are located in the middle frequency channels. With the transform, one is able to zoom into desired frequency channels and performs further decomposition. In contrast, the conventional wavelet transform only decomposes subsignals in low frequency channels. A progressive texture classification algorithm which is not only computationally attractive but also has excellent performance is developed.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Padded Frames: A Novel Algorithm for Stable Scheduling in Load-Balanced Switches (2006)

The load-balanced Birkhoff-von Neumann switching architecture consists of two stages: a load balancer and a deterministic input-queued crossbar switch. The advantages of this architecture are its simplicity and scalability, while its main drawback is the possible out-of-sequence reception of packets belonging to the same flow. Several solutions have been proposed to overcome this problem; among the most promising are the uniform frame spreading (UFS) and the full ordered frames first (FOFF) algorithms. In this paper, we present a new algorithm called padded frames (PF), which eliminates the packet reordering problem, achieves 100% throughput, and improves the delay performance of previously known algorithms.
Emerging roles of lipid metabolism in cancer metastasis (2017)

Cancer cells frequently display fundamentally altered cellular metabolism, which provides the biochemical foundation and directly contributes to tumorigenicity and malignancy. Rewiring of metabolic programmes, such as aerobic glycolysis and increased glutamine metabolism, are crucial for cancer cells to shed from a primary tumor, overcome the nutrient and energy deficit, and eventually survive and form metastases. However, the role of lipid metabolism that confers the aggressive properties of malignant cancers remains obscure. The present review is focused on key enzymes in lipid metabolism associated with metastatic disease pathogenesis. We also address the function of an important membrane structure-lipid raft in mediating tumor aggressive progression. We enumerate and integrate these recent findings into our current understanding of lipid metabolic reprogramming in cancer metastasis accompanied by new and exciting therapeutic implications.
A peripheral marker for schizophrenia: Increased levels of D3 dopamine receptor mRNA in blood lymphocytes (2001)

Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans the biological, physical, and social sciences.
Hemopoiesis in ectopically implanted bone marrow. (1984)

Ectopically implanted bits of marrow undergo a regenerative process that recapitulates the marrow ontogeny. This process is possible only because marrow tissue has considerable angiogenic potential. The regenerative process originates from marrow stroma, leading to the formation of primitive mesenchyme, osteoid bone, reconstitution of marrow organization including its distinctive sinusoidal system, and repopulation with circulating hemopoietic stem cells. Expansion of hemopoiesis is then associated with bone resorption. Also, few adipose cells develop and they are interspersed with hemopoiesis. The final product is a hemopoietic nodule surrounded by a shell of bone. A similar process occurs within the marrow cavity after ablation of the marrow tissue. In yellow marrow implants, the subsequent development of adipose tissue replaces entirely the hemopoietic tissue. Splenic implants can also regenerate in an analogous fashion despite their lack of significant angiogenic potential. As a model system, ectopic implantation of marrow has been the forerunner of long-term marrow culture and has provided important information on the relationship between hemopoietic cells and their supporting stroma. It has also led us to further understanding of the relationship between the marrow and its surrounding bone. Moreover, it has been an excellent system to study the relationship between red and yellow marrow and their interconversion. The full potential of this model system has not yet been fully realized. In application, for example, the conversion of yellow to red marrow can be exploited to reactivate the areas of hemopoietically inactive marrow in the limbs. Such exploitation may permit more liberal use of ablative radiotherapy in malignant diseases, particularly those of the lymphoreticular system. In basic research, in conjunction with long-term bone marrow culture, ectopic marrow implantation can yet provide considerable information on the role of stroma and bone in hemopoiesis.
General discussion (1960)

B. J. Mason, W. J. Dunning, E. R. Buckle, N. H. Fletcher, H. Wilman and W. R. Lane, Discuss. Faraday Soc., 1960, 30, 59 DOI: 10.1039/DF9603000059
The Petroleum System (1994)

The petroleum system concept is a reliable and logical way to judge and describe the petroleum potential and exploration risks of undrilled propects, plays, and basins. In 19 chapters on petroleum system basics and 18 case study chapters, this comprehensive volume provides an integrated look at the processes of petroleum generation in active source rocks, migration, and accumulation in traps.
The ammonium sulfate inhibition of human angiogenin (2016)

In this study, we investigate the inhibition of human angiogenin by ammonium sulfate. The inhibitory potency of ammonium sulfate for human angiogenin (IC50 = 123.5 ± 14.9 mm) is comparable to that previously reported for RNase A (119.0 ± 6.5 mm) and RNase 2 (95.7 ± 9.3 mm). However, analysis of two X-ray crystal structures of human angiogenin in complex with sulfate anions (in acidic and basic pH environments, respectively) indicates an entirely distinct mechanism of inhibition. While ammonium sulfate inhibits the ribonucleolytic activity of RNase A and RNase 2 by binding to the active site of these enzymes, sulfate anions bind only to peripheral substrate anion-binding subsites of human angiogenin, and not to the active site.
Multiparty Key Agreement Using Bilinear Map. (2007)

⎯ A key agreement protocol is a cryptographical primitive which allows participants to share a common secret key via insecure channel. In particular, a multiparty key agreement protocol is a key agreement protocol that can manage arbitrary number of participants at once. In the security point of view, authentication and forward secrecy are the most important requirements in such protocols. One interesting problem in key agreement protocols is to construct a multiparty key agreement protocol satisfying the above security requirements with minimal number of communication rounds (i.e. one-round). In literature, there has been no one-round multiparty key agreement protocol that satisfies both of authentication and forward secrecy. In this paper, we present a new multiparty key agreement protocol using bilinear map and adopting the key generation center. The protocol demands only one–round for arbitrary number of participants to share a group key and satisfies both authentication and (partial) forward secrecy. Keywords⎯Multiparty Key Agreement, Authentication, Bilinear Map, Weil Pairing