gebhart/patrepeval huggingface dataset:
Comparison of cloud liquid water paths derived from in situ and microwave radiometer data taken during the SHEBA/FIREACE (2001)

Mean cloud liquid water path LWP derived from microwave measurements using the standard ARM retrieval technique is nearly twice as large as coincident in situ aircraft data taken over the SHEBA ice camp in the Arctic during FIRE ACE. Using an algorithm adopted from satellite remote sensing that more completely accounts for the temperature dependence of water absorption and atmospheric gas absorption results in a 25 to 45 % reduction in LWP values relative to the standard ARM estimates. If possible precipitation cases are excluded, the mean results from the new technique differ by only 3% from the in situ data. Greater differences for heavier clouds may result from in situ probe uncertainties. This algorithm should provide accurate LWP retrievals for a variety of cloud conditions from the tropics to the highly supercooled Arctic clouds.
Irradiation-Induced Damage to the Salivary Glands: The Role of Redox-Active Iron and Copper (1997)

The mechanism of irradiation-induced hypofunction of the salivary glands is a process that is not fully understood. Here we examine the hypothesis that intracellular and redox-active ions of iron and copper, which are associated with the secretion granules, play a catalytic role in the irradiation-induced damage. Rats were subjected to head and neck irradiation (15 Gy X rays) and allowed to recover for 2 months. The function of the parotid and submandibular glands was then determined by pilocarpine-stimulated salivary secretion. A 45% decrease in the function of both glands was obtained when compared to nonirradiated controls. Treatment prior to irradiation (90 min) with cyclocytidine (200 mg/kg) led to a massive degranulation of the parotid gland and yielded nearly complete protection from radiation-induced damage. In contrast, pilocarpine stimulation prior to irradiation led to a marginal degranulation of the parotid gland and yielded only 13% protection. Neither agent caused degranulation of the submandibular gland mucous cells or yielded functional protection of this gland. Treatment with both agents yielded a marked increase in iron, copper and manganese levels in the parotid gland saliva. An analogous marked increase in the redox activity of iron and copper ions was recorded for the parotid saliva stimulated by pilocarpine and cyclocytidine. Pilocarpine-stimulated submandibular gland saliva contained metal levels similar to those of the parotid gland saliva. However, no redox activity and no increase in metal mobilization could be demonstrated in the submandibular gland saliva stimulated by both agents. The correlation between the patterns of gland degranulation, mobilization of redoxactive metals and the protection of gland function, for both parotid and submandibular glands, focuses attention on the catalytic roles played by transition metal ions in promoting free radical reactions, which likely participate in the process of injury to the tissue.
An improved MPPT technique for high gain DC-DC converter using model predictive control for photovoltaic applications (2014)

This paper presents an enhanced Maximum Power Point Tracking (MPPT) of Photovoltaic (PV) systems by means of Model Predictive Control (MPC) techniques. The PV array can feed power to the load through a DC/DC converter boosting the output voltage. Due to stochastic behavior of solar energy, MPPT control technique of PV arrays is required to operate at maximum power point. Extracting the maximum power from PV systems has been widely investigated within the literature. The main contribution of this paper is enhancement of the Incremental Conductance (INC) method through a fixed step predictive control under measured fast solar radiation variation. The proposed predictive control to achieve Maximum Power Point (MPP) speeds up the control loop since it predicts error before the switching signal is applied to the selected high gain multilevel DC-DC converter. Comparing the developed technique to the conventional INC method shows significant improvement in PV system performance. Experimental validation is presented using the dSpace CP 1103 to implement the proposed MPC-MPPT.
Polymorphisms of the DAX1 and EGR4 Genes are Not Common Causes of Abnormal Spermatogenesis (2008)

The study of gene mutations causing sequence variation in spermatogenesis-related genes has revealed a highly stable spermatogenic code with little variability and even fewer disease-causing mutations. The current study supports the same trend, indicating that EGR4 and DAX1, two spermatogenesis-related genes, have a high genetic fidelity and do not contain polymorphic sites that would lead to a disease state. This was determined from a population of 192 men, 96 control samples from men with known paternity, acquired from the Utah Genetic Reference Project (UGRP), and 96 infertile men. The diagnosis of the infertile men was stratified amongst three diagnostic groups, non-obstructive azoospermic, severe oligozoospermic, and men with abnormal protamine expression.
Biomechanical Stability of Intramedullary Nailed High Proximal Third Tibial Fractures With Cement Augmented Proximal Screws (2005)

Lower bone density decreased the stability of the uncemented construct; however, cement augmentation of the proximal screws showed a trend to eliminate this effect in the varus/valgus loading configuration and should be considered when nailing proximal third tibial fractures in osteoporotic patients.
Inkjet Printing for Producing Li-Ion Secondary Batteries (2020)

Recently, emerging devices such as IoT (internet of things) sensors and wearable devices require lithium-ion batteries (LIBs) with flexibility, various forms in terms of shape and size, and high power density. As required of these points, we have developed a new approach to producing free-designed cathodes and anodes for LIBs using inkjet printing. In this study, we mobilized all our accumulated technological expertise, including ceramic particle grinding technology and high dispersion technology to develop a new printable dispersion liquid for electrode materials. Most types of cathode and anode materials have been successfully used to demonstrate high concentration and low viscosity dispersion liquid for an inkjet printing with high productivity. The thickness of an inkjet printed electrode can be controlled by the number of droplets landed on the current collector. Because of the digital tuning of the thickness, we can obtain a thinner electrode with high-power density than the one fabricated by the conventional coating methods. In order to demonstrate the high-power usage of inkjet-printed electrodes, we fabricated a “R”-shaped prototype cell with capacity of 3mAh using common ceramic-type cathode and anode materials. As a result of the low impedance of inkjet-printed electrodes, the prototype cell can operate over 30C rate. This prototype cell had enough power to send data collected on temperature and humidity every five seconds via Bluetooth to a computer.
Data-Adaptive Detection of a Weak Signal (1983)

Motivated by a form of the likelihood-ratio-tesf statistic for detection of a rank-one Gaussian signal in colored Gaussian noise, we apply our earlier technique for estimation of a low-rank signal to the problem of estimating and subtracting the waveform of a strong sinusoidal interference prior to detection of a weak sinusoidal signal. We consider the difficult case in which samples of data are taken over a short interval of time or space and the frequencies of the sinusoidal signal and sinusoidal interference are more closely spaced than the reciprocal of the extent of the aperture. The method can be applied to cases of nonsinusoidal and/or random signals and interference. The most important assumption is that when the samples of the interference are arranged in matrix form the matrix is approximately of low rank in the sense that, with high probability, the interference-only matrix can be well approximated by a matrix of low rank.
Use of Disposable Punch Biopsy Device to Add Foley Catheter Fenestration to Improve Drainage of Post Radical Prostatectomy Anastomotic Leak (2019)

Based on these experimental results, we recommend using a 3.0 mm punch biopsy in an 18 Fr catheter 1.0 cm. proximal to the balloon for an auxiliary drain site in Foley catheter when the anastomosis is not watertight or the surgeon has reason to believe the patient is at higher risk for an AL Factors such as history of pelvic radiation, abnormal anatomy, large prostate, post-surgical hematoma formation, obesity, previous prostatic surgery, difficult anastomosis, blood loss and postoperative urinary tract infection may make use of this type of device more attractive.
A study on split-output TSPC CMOS circuits (2002)

In this paper, we present a heuristic study of a class of CMOS true single-phase clocked circuits (TSPC). TSPC circuits have proven to yield good performances at high frequencies. The proposed method may speed up design by identifying technology insensitive circuit properties. Our study focuses on split-output circuits which are believed to yield better performances than the other single-phase clocked circuits. We also present a characterization of the performances of these circuits as a function of load with NORTEL 0.8 /spl mu/m CMOS technology. With realistic (nonideal) Hspice simulated netlist extracted from layout, we observed that the maximum operating frequency for split-output was 1.17 GHz. It is shown that the maximum speed of TSPC latches obtained with our simple suboptimal design method does not directly decrease with loading as in static gates. Finally, the speed degradation of the studied circuit with degraded clocks is characterized.
Chiral analysis of anti‐acquired immunodeficiency syndrome drug, 9‐(<i>R</i>)‐[2‐(phosphonomethoxy)propyl]adenine (tenofovir), and related antiviral acyclic nucleoside phosphonates by CE using β‐CD as chiral selector (2009)

A new CZE method has been developed for chiral analysis of an important anti-acquired immunodeficiency syndrome drug, 9-(R)-[2-(phosphonomethoxy)propyl]adenine ((R)-PMPA, tenofovir), and six related antiviral acyclic nucleoside phosphonates using beta-CD as a chiral selector. The influence of the composition, concentration and pH of the BGE and the type and concentration of chiral selector on enantiomer resolution was investigated. Complete separations of (R,S)-enantiomers of PMPA with very good resolution (R(s)=1.50-3.64) were achieved within a short time (4-15 min) in 20-50 mM sodium borate or sodium tetraborate BGEs, pH 10.0, at 20 mg/mL concentration of beta-CD. (R,S)-enantiomers of five similar PMPA analogs containing purine bases (adenine, diaminopurine or guanine) and hydroxyl or fluor substituents at C3 carbon atom of propyl chain were baseline separated within 10-17 min in 35 mM sodium tetraborate BGE, pH 10.0, at 20 mg/mL beta-CD concentration. Another important antiviral used by acquired immunodeficiency syndrome patients, derived from pyrimidine base cytosine, 1-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]cytosine (cidofovir), and the (R)-enantiomer of this drug were successfully separated in 50 mM sodium tetraborate BGE, pH 10.5, at 20 mg/mL beta-CD concentration within 45 min. Using the UV-absorption detection at 206 nm, the concentration detection limits of the analyzed acyclic nucleoside phosphonates were determined in the submicromolar to micromolar range (0.15-2.51 microg/mL level).
ChemInform Abstract: REARRANGEMENTS OF OXAHOMOADAMANTANE DERIVATIVES IN ACIDIC MEDIA (1982)

Abstract Bei der Behandlung mit Schwefelsäure oder Thionylhalogeniden erhält man aus dem Oxahomoadamantan (I) ‐vermutlich über Zwischenstufen wie (II)‐ die Oxa‐adamantane (III) und die Oxahomoadamantane (IV) in unterschiedlichen Mengen.
Enterococcal Bacteremia: Risk Factors for Vancomycin Resistance and Predictors of Mortality (1999)

These results suggest that restrictions on antibiotic use, particularly in patients with renal insufficiency and neutropenia, may help to combat the rising incidence of VRE. Although patients with VRE bacteremia demonstrated higher mortality rates than patients with infection due to susceptible isolates, vancomycin resistance was not an independent predictor of mortality in these patients and likely serves more as a marker of underlying severity of illness.
Successive modification of polydentate complexes gives access to planar carbon- and nitrogen-based ligands (2019)

Polydentate complexes containing combinations of nitrogen and carbon (N and C) ligating atoms are among the most fundamental and ubiquitous molecules in coordination chemistry, yet the formation of such complexes with planar high-coordinate N/C sites remains challenging. Herein, we demonstrate an efficient route to access related complexes with tetradentate CCCN and pentadentate CCCCN and NCCCN cores by successive modification of the coordinating atoms in complexes with a CCCC core. Combined experimental and computational studies reveal that the rich reactivity of metal-carbon bonds and the inherent aromaticity of the metallacyclic skeletons play key roles in these transformations. This strategy addresses the paucity of synthetic approaches to mixed N/C planar pentadentate chelating species and provides valuable insights into the synthesis of carbon-based high-coordinate complexes. Furthermore, the resulting complexes are the examples of organometallic species with combined photoacoustic, photothermal, and sonodynamic properties, which makes them promising for application in related areas.
CFD in Drying Technology – Spray‐Dryer Simulation (2007)

This chapter contains sections titled: Introduction The Euler–Lagrange Approach: an Extended Model for Spray-dryer Calculations Droplet-drying Models Collisions of Particles Example of a Spray-dryer Calculation Prediction of Product Properties Summary Additional Notation used in Chapter 5
Stability and Oligomeric Equilibria of Refolded Interleukin-1β Converting Enzyme (1996)

We report the preparation and characterization of interleukin-1beta converting enzyme (ICE) refolded from its p20 and p10 protein fragments. Refolded ICE heterodimer (p20p10) was catalytically active but unstable, and in size exclusion chromatography eluted at an apparent molecular mass of 30 kDa. The mechanisms of the observed instability were pH-dependent dissociation at low enzyme concentrations, and autolytic degradation of the p10 subunit at high concentrations. Binding and subsequent removal of a high affinity peptidic inhibitor increased the apparent molecular mass to 43 kDa (by size exclusion chromatography), and significantly increased its stability and specific activity. Chemical cross-linking and SDS-polyacrylamide gel electrophoresis analysis of the 43-kDa size exclusion chromatography conformer revealed a 60-kDa species, which was absent in the 30-kDa conformer, suggesting that inhibitor binding caused formation of a (p20p10)2 homodimer. The observation of a reversible equilibrium between ICE (p20p10) and (p20p10)2 suggests that analogous associations, possibly between ICE and ICE homologs, can occur in vivo, resulting in novel oligomeric protease species.
A randomized, double-blind, placebo-controlled, multicenter, multinational, phase II trial of L-BLP25 in patients with colorectal carcinoma following R0/R1 hepatic metastasectomy. (2012)

TPS3641^ Background: Approximately 15-20% of patients diagnosed with colorectal cancer (crc) develop metastatic disease. Surgical resection remains the only potentially curative treatment. 5-year survival following R0-resection of liver metastases lies ~28 -39%. Recurrence occurs in ~70% of pts. Adjuvant chemotherapy has not significantly improved clinical outcomes. The primary objective of the LICC trial (L-BLP25 in Colorectal Cancer) is to analyze whether L-BLP25, an active cancer immunotherapy, extends recurrence-free survival (RFS) time over placebo in colorectal cancer pts following R0/R1 resection of hepatic metastases. L-BLP25 targets MUC1 glycoprotein, which is highly expressed in hepatic metastases from crc. In a phase IIB trial, L-BLP25 showed acceptable tolerability and a trend toward longer survival in pts with stage IIIB NSCLC. Methods: This is a multinational, phase II, multicenter, randomized, double-blind, placebo-controlled trial with a sample size of 159 pts from 20 centers in 3 countries. Pts must have stage IV cr adenocarcinoma limited to liver metastases. Following complete resection of the primary tumor and all syn-/metachronous metastases, eligible pts are randomized 2:1 to receive either L-BLP25 or placebo. Those allocated to L-BLP25 receive a single dose of 300 mg/m 2 cyclophosphamide (CP) 3 days before first L-BLP25 dose, then primary treatment with sc L-BLP25 930 μg once weekly for 8 weeks, followed by maintenance doses at 6-week (years 1 and 2) and 12-week (year 3) intervals until recurrence. In the control arm, CP is replaced by saline solution and L-BLP25 by placebo. Primary endpoint: RFS time. Secondary endpoints: OS time, safety status, tolerability, RFS/OS in MUC-1 positive cancers. Exploratory immune response analyses are planned. First recruitment was of Q3 2011. To date, 8 of 20 centers are initiated and 4 pts recruited. Completion of recruitment is scheduled for Q3 2013. Primary endpoint will be assessed in Q3 2016: Follow-up will end Q3 2017. No interim analysis is planned. Design and implementation of this vaccination study in colorectal cancer is feasible. No major issues identified during setup of the study.
EFFECT OF DEGREE OF COMPRESSION ON TEXTURE PROFILE PARAMETERS (1981)

Texture Profile Analysis (TPA) was performed on apple, carrot, frankfurter, cream cheese and pretzels with the Instron and the effect of the degree of compression on TPA parameters measured at a compression speed of 5 cm/min. Fracturability is almost independent of the degree of compression. Hardness, area 1, area 2, cohesiveness, gumminess, and chewiness usually increase with increasing compression but the rate of increase varies widely. Springiness increases for pretzel sticks and decreases for the four other commodities as compression increases. Adhesive force and adhesive area of cream cheese increase but stringiness decreases with increasing compression. Since the TPA parameters vary so widely with degree of compression, all TPA measurements should standardize the degree of compression and clearly state in reports what compression was used.
A 10-Watt cw photodissociation laser with iodo-perfluoro-tert-butane (1989)

The operation of a 10-W cw iodine laser system with the iodide t-C4F9I was achieved. The laser system was driven by a 40-kW solar simulating irradiance from a long argon arc that was previously operated with the common iodide n-C3F7I.1
Optical Monitoring of Laser-Induced Plasma Derived from Graphite and Characterization of the Deposited Carbon Film (1994)

Mechanisms of the deposition of carbon thin films by the laser ablation of graphite were investigated by monitoring the plasma emission. Parameters such as electron density, ionization temperature, and vibrational temperature during plasma growth were evaluated as a function of the laser power density and the surrounding atmosphere. Also, Raman spectra of the deposited films were measured so that the particle size can be estimated from the intensity ratio of the Raman bands around 1360 and 1580 cm −1 . The increase in power density caused an increase in ionization temperature and vibrational temperature of carbon species in the plasma but a decrease of particle size of the deposited thin films. The existence of 10 Torr of helium as a surrounding atmosphere caused drastic changes in the plasma parameters. The films deposited with helium atmosphere showed a low optical band gap, which indicates heat restructuring of ablated graphite particles in the hot plasma. The results can be explained with a simple model of laser ablation and the subsequent interaction of ablated particles with the laser-induced plasma.
Random access MAC for efficient broadcast support in ad hoc networks (2002)

Wireless communications are becoming an important part of our everyday lifestyle. One major area that will have an enormous impact on the performance of wireless ad hoc networks is the medium access control (MAC) layer. Current random access MAC protocols for ad hoc networks support reliable unicast but not reliable broadcast. We propose a random access MAC protocol, broadcast support multiple access (BSMA), which improves the broadcast reliability in ad hoc networks.
Cardiac Function after Eight Hour Storage by Using Polyethylene Glycol Hemoglobin Versus Crystalloid Perfusion (2000)

Efforts to extend myocardial preservation for transplantation by crystalloid perfusion have been limited by edema and compromised function. We hypothesized that hypothermic perfusion preservation with a polyethylene glycol (PEG) conjugated hemoglobin solution may extend preservation times. The purpose of this study was to compare cardiac function after continuous perfusion by using a hypocalcemic, normokalemic crystalloid perfusate with and without the addition of PEG-hemoglobin (Hb). The hearts of 20 anesthetized and ventilated New Zealand White rabbits were harvested after cold cardioplegic arrest. Group I (n = 10) hearts were continuously perfused with a hypocalcemic, normokalemic 3% bovine PEG-Hb solution at 20 degrees C and 30 mm Hg for 8 hours. Group II (n = 10) hearts were continuously perfused with an identical crystalloid solution without PEG-Hb for 8 hours under the same conditions as group I hearts. Cardiac function was measured with a left ventricular force transducer after transfer to a standard crystalloid Langendorff circuit at 37 degrees C and an aortic root pressure of 59 mm Hg. After 8 hours of perfusion preservation, heart rate was similar for groups I and II (p = not significant [NS]). Coronary blood flow after and during preservation was similar between PEG-Hb and crystalloid preserved hearts (p = NS). Left ventricular developed pressure, peak dP/dt, and peak -dP/dt were superior in hearts preserved with PEG-Hb. Percent water of total ventricular weight was 82.0% for group I and 81.6% for group II (p = NS). Continuous perfusion preservation of rabbit hearts for 8 hours with a hypocalcemic normokalemic PEG-Hb based solution at 30 mm Hg and 20 degrees C yields left ventricular function that is superior to perfusion with a similar crystalloid solution without PEG-Hb, despite similar myocardial edema and coronary flow. Extended cardiac perfusion preservation with this PEG-Hb based solution deserves further study, including comparison with traditional cardioplegic preservation solutions.