gebhart/patrepeval huggingface dataset:
Use of two calcium concentrations in hemodialysis – Report of a 20-year clinical experience (2009)

Over the past almost 50 years several calcium concentrations in the dialysate (CaD) have been used to balance calcium in hemodialysis (HD) patients but a consensus as to which is most appropriate has not been established. Moreover, since the late 1980s, further confusion has been caused following the use of calcium salts as intestinal phosphate binders. This paper reports results of 387 chronic HD patients with respect to secondary hyperparathyroidism (sHPT) and renal osteodystrophy (ROD) of a single center over 20 years. The most important therapeutic measures applied were use of only 2 CaD, 1.5 and 1.75 mmol/l, with very few exceptions, administration of either calcium-containing or calcium-magnesium-containing and/or calcium-free phosphate binders, no dietary restrictions and continuous compensation of uremic acidosis via dialysate and oral supplements of bicarbonate. Using one of the two CaD and selective administration of different phosphate binders for fine adjustment of serum calcium through this combination, we were able to maintain in the long term almost physiological conditions. With exception of the phosphate metabolism, most physiological functions with regard to sHPT and ROD returned close to normal. As a result, the incidence of hypercalcemia, hypocalcemia, extraosseous, extravascular calcification, bone pain and spontaneous bone fractures was extremely low. We conclude that the clinical advantages of the therapeutic measures, above all precise balance of calcium homeostasis, in our investigation were demonstrated by high survival rates (92% after the first year on HD, 82% after 2, and 55% after 5 years), low incidence of cardiovascular fatalities (about 25%), and very low incidence of sHPT (mostly normal parathyroid hormone levels, 1 parathyrdoidectomy within 20 years).
1C23 Development of autonomous battery exchange system for multi-rotor helicopter(The 12th International Conference on Motion and Vibration Control) (2014)

This paper presents a heliport for industrial multi rotor helicopter which is possible to exchange battery automatically. Recent years, study of multi rotor helicopter is active in all over the world and it develops for practical use is in progress. In our group, we develop multi rotor helicopter named Mini-Surveyor, and we are trying various studies. However, flight time of multi rotor helicopter is as short as 10 to 15 minutes because most of them are drive by lithium polymer battery. So, in order to extend the flight time of the multi rotor helicopter, we develop autonomous battery exchange system. We have developed an automatic battery exchange system than before. But it is directed to small multi-rotor helicopter, so payload is too small to operate using some device and there was a problem in landing system. So now, we develop new automatic battery exchanger. This new system is developed based on old system, but when the multi rotor helicopter take off and land, it performs accurate take off and land at battery exchanger using by the Vicon system which is high accuracy positioning system. In addition, we develop transportable heliport system which is consisting of autonomous battery exchanger, Vicon system, generator and others. It is designed to be able to operate multi rotor helicopter and battery exchanger in long time at dangerous place such as disaster cannot stay a person and it is possible to operate the multi rotor helicopter only the heliport system. Here we report design of heliport system including autonomous battery exchanger and discuss autonomous takeoff and landing from the heliport.
Geometrical-optics solution to light scattering by droxtal ice crystals (2004)

We investigate the phase matrices of droxtals at wavelengths of 0.66 and 11 microm by using an improved geometrical-optics method. An efficient method is developed to specify the incident rays and the corresponding impinging points on the particle surface necessary to initialize the ray-tracing computations. At the 0.66-microm wavelength, the optical properties of droxtals are different from those of hexagonal ice crystals. At the 11-microm wavelength, the phase functions for droxtals are essentially featureless because of strong absorption within the particles, except for ripple structures that are caused by the phase interference of the diffracted wave.
On OFDM-based cognitive radio spectrum sharing systems with random access (2012)

The performance of an orthogonal frequency-division multiplexing (OFDM)-based spectrum sharing communication system that assumes random access and no information about the primary user's (PU) channel occupation information is studied. Also, no cooperation, information exchange overhead, or subcarrier allocation mechanism between the secondary users (SUs) is assumed. SUs randomly access the subcarriers of the primary network and collide with the PUs' subcarriers with a certain probability. To maintain the quality of service (QoS) requirement of PUs, the interference that SUs causes onto PUs is controlled by adjusting SUs transmit power below a predefined threshold, termed interference temperature. Herein paper, the average capacity of SU with subcarrier collisions is employed as performance measure to investigate the proposed random access scheme. Bounds and scaling laws of average capacity with respect to the number of SUs', PUs' and available subcarriers are derived, and corroborated by computer simulations.
Bile salt-stimulated lipase from human milk and mucosal transmission of pathogens during breastfeeding (2013)

Human milk contains an array of antimicrobial products that can interfere with pathogens being transmitted from mothers to their infants during breastfeeding. In this chapter we specifically discuss factors that can influence human immonodeficiency virus type-1 (HIV-1) transmission. We discuss the potential mechanisms through which HIV-1 can cross a mucosal barrier and the array of cell types involved with such a mechanism. One of the major cells proposed to be involved with transmission are dendritic cells (DCs) which express an array of receptors which carry the potential to interact with pathogen antigens as well as whole pathogens. The C-type lectin DC-specific ICAM-3 grabbing non-intergrin (DC-SIGN) has specifically been postulated to mediate mucosal transmission of HIV-1. The gp120 envelope protein of HIV-1 can interact with DC-SIGN and promote pathogen capture and uptake and subsequent presentation of virus to CD4+ T-lymphocytes, through a mechanism known as trans-infection. HIV-1 is not the only pathogen known to bind DC-SIGN and this mechanism in all likelihood involved in transmission of a number of viruses, bacteria and fungi. Factors in human milk with the potential to modulate pathogen capture would therefore have the capacity to influence transmission. We have shown that a human glycoprotein found in human milk, bile salt-stimulated lipase, can potently bind DC-SIGN and prevent HIV-1 capture and transfer to CD4+ T-lymphocytes. This protein is composed of a variable number of 11 amino acid repeats at the C-terminus and this variation can be associated with strength of binding DC-SIGN. Factors with similar activity have also been identified in other bodily fluids suggesting that we have evolved ways of interfering with pathogen transmission across a mucosal surface. Since DCs are modulators of immune responses it is tempting to speculate that such factors skew immunity towards a desired response beneficial for the exposed host.
FFT-based RLS in signal processing (1993)

An algorithm for fast adaptive filtering is proposed. The algorithm applies a FFT (fast Fourier transform)-based iterative method and uses sliding data windows involving block updating and downdating computations. The method is stable and robust, and computes the tap weight filter vector in O(L log N) operations, where the sliding window Toeplitz data matrix X is L-by-N. The complexity thus generally lies between those of the family of unstable but fast, O(N), methods and the stable but slow O(N/sup 2/) Cholesky factor updating methods.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Improving Educational Outcomes of Hispanic Students in a Professional Degree Program (2010)

In an attempt to reduce the educational achievement gap of Hispanic students in a professional degree program, two courses grounded in the Keller method were implemented at a pharmacy school. The Keller method is characterized by breaking course content into modules, then allowing students to test and repeatedly remediate and retest until competency is achieved. Outcomes from this intervention-based cohort study suggest that the Keller method is effective in reducing the educational achievement gap of Hispanic students in a professional degree program.
Fluoroolefins. XI. The Conversion of Fluoroolefins to Fluoroalkyl Nitroso Compounds via Alkylmercury Compounds (1964)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTFluoroolefins. XI. The Conversion of Fluoroolefins to Fluoroalkyl Nitroso Compounds via Alkylmercury CompoundsPaul Tarrant and D. E. O'ConnorCite this: J. Org. Chem. 1964, 29, 7, 2012–2013Publication Date (Print):July 1, 1964Publication History Published online1 May 2002Published inissue 1 July 1964https://pubs.acs.org/doi/10.1021/jo01030a503https://doi.org/10.1021/jo01030a503research-articleACS PublicationsRequest reuse permissionsArticle Views46Altmetric-Citations15LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Faculty Opinions recommendation of Chaperonin overexpression promotes genetic variation and enzyme evolution. (2009)

Most protein mutations, and mutations that alter protein functions in particular, undermine stability and are therefore deleterious. Chaperones, or heat-shock proteins, are often implicated in buffering mutations, and could thus facilitate the acquisition of neutral genetic diversity and the rate of adaptation. We examined the ability of the Escherichia coli GroEL/GroES chaperonins to buffer destabilizing and adaptive mutations. Here we show that mutational drifts performed in vitro with four different enzymes indicated that GroEL/GroES overexpression doubled the number of accumulating mutations, and promoted the folding of enzyme variants carrying mutations in the protein core and/or mutations with higher destabilizing effects (destabilization energies of >3.5 kcal mol(-)(1), on average, versus approximately 1 kcal mol(-)(1) in the absence of GroEL/GroES). The divergence of modified enzymatic specificity occurred much faster under GroEL/GroES overexpression, in terms of the number of adapted variants (>or=2-fold) and their improved specificity and activity (>or=10-fold). These results indicate that protein stability is a major constraint in protein evolution, and buffering mechanisms such as chaperonins are key in alleviating this constraint. PMID: 19494908 Funding information This work was supported by: PHS HHS, United States Grant ID: W81XWH-07-2-0020
Control Strategy for Biventricular Assistance with Mixed‐Flow Pumps (2000)

A left ventricular assist device (LVAD) is an effective method to rescue severe heart failure. Although some require a biventricular assist, the control method for the biventricular assist device (BVAD) with a rotary pump is rarely shown. The objective of this study was to investigate the strategy for controlling BVAD with rotary pumps by in vivo studies. Using 5 piglets, we set a BVAD through a left thoracotomy and made global ischemia for 30 min by clamping the base of the ascending aorta. After unclamping, the analysis of pumping performance acted for 6 h reperfusion. We set the target flow of the LVAD and set the right ventricular assist device (RVAD) speed limit as less than when the atrial collapse occurs. To detect the ventricular collapse without any specific sensor, we calculated the index of current amplitude from motor current waveform and simultaneous mean current value. In all cases, over 6 h of observation was performed, and the RVAD was weaned almost automatically.
Evidence against hole filling by Pr in<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mrow><mml:msub><mml:mrow><mml:mi mathvariant="normal">YBa</mml:mi></mml:mrow><mml:mrow><mml:mn>2</mml:mn></mml:mrow></mml:msub></mml:mrow></mml:math><mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mrow><mml:msub><mml:mrow><mml:mi mathvariant="normal">Cu</mml:mi></mml:mrow><mml:mrow><mml:mn>3</mml:mn></mml:mrow></mml:msub></mml:mrow></mml:math><mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mrow><mml:msub><mml:mrow><mml:mi mathvariant="normal">O</mml:mi></mml:mrow><mml:mrow><mml:mn>7</mml:mn></mml:mrow></mml:msub></mml:mrow></mml:math> (1990)

Electron-energy-loss spectroscopy has been used to investigate the changes of the electronic structure in ${\mathrm{Y}}_{1\mathrm{\ensuremath{-}}\mathit{x}}$${\mathrm{Pr}}_{\mathit{x}}$${\mathrm{Ba}}_{2}$${\mathrm{Cu}}_{3}$${\mathrm{O}}_{7}$ (0\ensuremath{\le}x\ensuremath{\le}1). The O 1s absorption edges and the low-energy-loss function indicate that Pr does not fill holes in the ${\mathrm{CuO}}_{2}$ planes. This suggests, by comparison with other experiments, that Pr localizes mobile holes thereby leading to the suppression of superconductivity and the metal-insulator transition.
BET specific surface area and pore structure of MOFs determined by hydrogen adsorption at 20 K (2010)

Low-pressure high-resolution hydrogen adsorption for the metal-organic framework MIL-101 are measured at 19.5 K and pressures below 57 kPa. The BET specific surface area and micropore volume are determined and compared to results from nitrogen adsorption at 77 K. Steps in the hydrogen adsorption isotherm are correlated to the pore structure of MIL-101.
An analytical approach to quantify uniformity artifacts for circular and noncircular detector motion in single photon emission computed tomography imaging (1987)

Uniformity artifacts in rotating gamma camera tomography will result if there are errors in the correction factors which are routinely calculated from a static uniformity flood image. The accuracy of the correction factors is a function of the statistics in the collected flood image. Since the factors are applied to each projection view, an error in a correction factor will propagate as a projection error at the same pixel location for each view. For circular detector motion, the error in each projection is reconstructed as a ring whose maximum amplitude varies approximately inversely proportional to the square root of the distance of the projection error from the center of rotation. For noncircular detector motion the artifacts are not rings but are more complicated geometric curves. Simulations show that statistical fluctuations in the reconstructed image will mask the uniformity artifacts provided the correction flood satisfies minimum count requirements. An analytical expression is derived for the percent root-mean-square (% rms) error in the reconstruction and is compared with the percent relative amplitude error (% RAE) of the reconstructed artifacts in order to obtain expressions for uniformity flood counting statistics. For an elliptical source distribution with total counts equal to CT, the uniformity statistics required to reconstruct elliptical disks is inversely proportional to the square root of the area: U greater than or equal to KCT/area 1/2. The constant K depends on the filter function and type of detector motion.
Effect of Trovafloxacin on Production of Cytokines by Human Monocytes (1998)

Antibiotics have previously been shown to have immunomodulatory effects. We examined the effect of the broad-spectrum fluoroquinoline antibiotic trovafloxacin on cytokine synthesis by monocytes obtained from healthy human volunteers and stimulated with either lipopolysaccharide or gram-positive cells (heat-killed Staphylococcus aureus [Pansorbin]). Trovafloxacin levels achievable in humans suppressed in vitro synthesis of each of the cytokines analyzed, viz., interleukin-1 alpha (IL-1 alpha), IL-1 beta, IL-6, IL-10, granulocyte-macrophage colony-stimulating factor, and tumor necrosis factor alpha. This effect was not due to direct effects of the drug on cellular viability; at these concentrations, trovafloxacin did not have demonstrable cytotoxicity for the monocytes, as determined by the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-tetrazolium bromide (MTT) assay. Although similar patterns of suppression of cytokine synthesis were observed in samples obtained from the same volunteers on different days, there were significant day-to-day variations. These results reveal that trovafloxacin possesses significant immunomodulatory activity in vitro and suggest that suppression of acute-phase inflammatory responses may occur in vivo, elicited through trovafloxacin's effect on cytokine synthesis by human monocytes.
High-Field Transport and Velocity Saturation in Synthetic Monolayer MoS<sub>2</sub> (2018)

Two-dimensional semiconductors such as monolayer MoS<sub>2</sub> are of interest for future applications including flexible electronics and end-of-roadmap technologies. Most research to date has focused on low-field mobility, but the peak current-driving ability of transistors is limited by the high-field saturation drift velocity, v<sub>sat</sub>. Here, we measure high-field transport as a function of temperature for the first time in high-quality synthetic monolayer MoS<sub>2</sub>. We find that in typical device geometries (e.g. on SiO<sub>2</sub> substrates) self-heating can significantly reduce current drive during high-field operation. However, with measurements at varying ambient temperature (from 100 to 300 K), we extract electron v<sub>sat</sub> = (3.4 ± 0.4) × 10<sup>6</sup> cm/s at room temperature in this three-atom-thick semiconductor, which we benchmark against other bulk and layered materials. With these results, we estimate that the saturation current in monolayer MoS<sub>2</sub> could exceed 1 mA/μm at room temperature, in digital circuits with near-ideal thermal management.
Síntese e reatividade de α-metiltio sulfonas benzílicas orto- e meta-substituídas (1992)

+ C 2 H 5 S Na /CH 3 0H 4.7.1. Dessu.lf'enilao de fenil a,a-(cmet.i1t.io}-para--nit.robenzil sulf'ona (73k) 4.7.2. Dessulfenilao de fenil a,a-(cmet.i1t.io)-met.a--nit.robenzil sulf"ona <73f) 4 .8. Sint.ese de benzaldeidos ort.o-e met.a-subst.i t.uidos pela decomposio t.rmica de fenil ort.o-e met.a-benzi! sulf'Ona:51 4.8.1. Decomposio t.rmica de f'enil a-met.i1t.io ort.o--met,xibenzil sulona (63a) 4.8.2. Decomposio t.rmica de f'enil a-met.i1t.io ort.o--nit.:robenzil .u.lf"ona <63b) 4.8.3. Decomposio t.rmica de f'enil a-met.ilt.io ort.o--met.ilbenzil .ulf'ona <630) 4.8.4. Decomposio t.rmica de f'enil a-met.ilt.io ort.o--cianobenzil sulfona (63d) 4.8.5. Decomposio t.rmica de f'enil a-met.ilt.io met.a--met,xibenzil sulona (639) 4.8.6. Decomposio t.rmica de fenil a-met.ilt.io met.a--nit.robenzil sulf'ona (63f') 152 4.8.7. Decomposio t.rmica de fenil a-met.ilt.io met.a--met.ilbenzil sulf"ona (63C) 1~3 4.8.8. Decomposio t.rmica de fanil a-met.i1t.io met.
State of the copper-containing component and the catalytic properties of Cu/ZSM-5 in selective NO reduction with propane (2014)

Supported Cu/ZSM-5 catalysts have been synthesized by ion exchange and impregnation using aqueous ammonia solutions of copper nitrate containing orbital-ordered copper ions. The state of the copper-containing component in the pore space of the catalysts and copper sorption in the catalysts have been investigated by a complex of physicochemical methods. The catalytic properties of Cu/ZSM-5 in the selective catalytic reduction of NO with propane are reported. The catalytic properties depend on the copper precursor structure and deposition method, which determine the size of the copper oxide clusters on the outer surface of zeolite crystals.
Birth of a Normal Girl After in Vitro Fertilization and Preimplantation (1993)

HANDYSIDE, ALAN H.; LESKO, JOHN G.; TARÍN, JUAN J.; WINSTON, ROBERT M. L.; HUGHES, MARK R.Author Information
Reversible Vasoconstriction Syndrome with Bilateral Basal Ganglia Hemorrhages (2011)

Reversible cerebral vasoconstriction syndrome (RCVS) is an increasingly recognized acute cerebrovascular condition that may produce myriad transient and sustained neurologic deficits as well as a host of radiologic features. We report the case of a woman with RCVS and a severe clinical syndrome with bilateral basal ganglia hemorrhages, cerebral infarctions, and marked vascular abnormalities. The patient made a near complete clinical recovery, representing an extreme and illustrative form of RCVS.
Allergenic relevance of nonspecific lipid transfer proteins 2: Identification and characterization of Api g 6 from celery tuber as representative of a novel IgE-binding protein family (2013)

Api g 6, a novel nsLTP2 from celery tuber represents the first well-characterized allergen in this protein family. Despite similar structural and physicochemical features as nsLTP1, immunological properties of Api g 6 are distinct which warrants its inclusion in molecule-based diagnosis of A. graveolens allergy.
Coronary dilator effects of intracoronary nifedipine and isosorbide dinitrate (1987)

Although both nitrates and calcium antagonists may be administered by the intracoronary route, the relative efficacy of these agents and of their combination is unknown. In this study, we investigated the coronary vasodilatory potential of intracoronary nifedipine, isosorbide dinitrate and their combination in patients undergoing routine coronary arteriography. Both normal and diseased segments of coronary arteries were studied. Coronary artery diameters were measured from 35 mm cine film before and after the administration of each drug. Two groups of 10 patients were studied: group I received nifedipine, 0.2 mg, followed by isosorbide dinitrate, 1 mg, group II received isosorbide dinitrate, 1 mg, followed by nifedipine, 0.2 mg. Both agents resulted in significant dilatation of normal and diseased segments of the coronary arteries when injected as the first drug, but neither nifedipine nor isosorbide dinitrate produced significant additional vasodilation when injected as the second drug. The degree of dilatation of both diseased and normal segments produced by either nifedipine or isosorbide dinitrate was similar, suggesting that the dose used, of either drug, produced near maximal coronary vasodilatation. Importantly, drug induced dilatation of stenotic segments was similar to that of normal segments.
ChemInform Abstract: Catalytic C—F Activation and Hydrodefluorination of Fluoroalkyl Groups (2009)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.