gebhart/patrepeval huggingface dataset:
A NOVEL NEURAL NETWORK APPROACH FOR FAULT SECTION ESTIMATION (2002)

Fault section estimation is of great importance to the restoration of power systems. In this paper, the application of Radial Basis Function Neural Network (RBF NN) to fault section estimation is addressed. The orthogonal least square algorithm has been extended to optimize the parameters of RBF NN. A classical Back Propagation Neural Network (BP NN) has been developed to solve the same problem for comparison. Computer test is conducted on a 4 bus test system and the test results show that the RBF NN is quite effective and superior to BP NN in fault section estimation.
Discrete square root filtering: A survey of current techniques (1971)

The conventional Kalman approach to discrete filtering involves propagation of a state estimate and an error covariance matrix from stage to stage. Alternate recursive relationships have been developed to propagate a state estimate and a square root error covariance instead. Although equivalent algebraically to the conventional approach, the square root filters exhibit improved numerical characteristics, particularly in ill-conditioned problems. In this paper, current techniques in square root filtering are surveyed and related by applying a duality association. Four efficient square root implementations are suggested, and compared with three common conventional implementations in terms of computational complexity and precision. The square root computational burden should not exceed the conventional by more than 50 percent in most practical problems. An examination of numerical conditioning predicts that the square root approach can yield twice the effective precision of the conventional filter in ill-conditioned problems. This prediction is verified in two examples. The excellent numerical characteristics and reasonable computation requirements of the square root approach make it a viable alternative to the conventional filter in many applications, particularly when computer word length is limited, or the estimation problem is badly conditioned.
Optical studies of AlN/n-Si(100) films obtained by the method of high-frequency magnetron sputtering (2008)

Morphological and optical (with reflection spectra in the range of 200–750 nm, transmission spectra in the range of 2–25 μm, and ellipsometry) studies were performed for AlN films that had a thickness of 2–3 μm and were obtained by the method of high-frequency magnetron sputtering of an aluminum target in a gas mixture of Ar and N2 (1: 3) with deposition onto single-crystal n-Si (100) substrates with a resistivity of 20–60 Ω cm. It is shown that the films are dense and transparent; they are amorphous with crystalline grains and can be used efficiently in thin-film technology for fabrication of modern microelectronic and optoelectronic devices.
Structural and functional analysis of fatty acid-binding proteins (2008)

The mammalian FA-binding proteins (FABPs) bind long-chain FA with high affinity. The large number of FABP types is suggestive of distinct functions in specific tissues. Multiple experimental approaches have shown that individual FABPs possess both unique and overlapping functions, some of which are based on specific elements in the protein structure. Although FA binding affinities for all FABPs tend to correlate directly with FA hydrophobicity, structure-function studies indicate that subtle three-dimensional changes that occur upon ligand binding may promote specific protein-protein or protein-membrane interactions that ultimately determine the function of each FABP. The conformational changes are focused in the FABP helical/portal domain, a region that was identified by in vitro studies to be vital for the FA transport properties of the FABPs. Thus, the FABPs modulate intracellular lipid homeostasis by regulating FA transport in the nuclear and extra-nuclear compartments of the cell; in so doing, they also impact systemic energy homeostasis.
New insight into the mechanism underlying the silk gland biological process by knocking out fibroin heavy chain in the silkworm (2018)

Accumulation of abnormal fib-H protein might arouse the activation of proteasomes as well as autophagy process, to promote the rapid degradation of such abnormal proteins and the silk gland cells. Our study therefore proposes a subsequent process of protein and partial cellular degradation caused by mutation of silk protein, which might be helpful for understanding its impact of the silk gland biological process, and further exploration the re-allocation of nitrogen in the silkworm.
Pilot Testing of Technologies to Treat Multiple Contaminants in Drinking Water at the Pine Hill School on the Ramah Navajo Reservation: A Collaborative Project between the Navajo Nation EPA and Sandia National Laboratories. (2006)

Abstract not provided.
Skeletal muscle membrane lipid composition is related to adiposity and insulin action. (1995)

The cellular basis of insulin resistance is still unknown; however, relationships have been demonstrated between insulin action in muscle and the fatty acid profile of the major membrane structural lipid (phospholipid). The present study aimed to further investigate the hypothesis that insulin action and adiposity are associated with changes in the structural lipid composition of the cell. In 52 adult male Pima Indians, insulin action (euglycemic clamp), percentage body fat (pFAT; underwater weighing), and muscle phospholipid fatty acid composition (percutaneous biopsy of vastus lateralis) were determined. Insulin action (high-dose clamp; MZ) correlated with composite measures of membrane unsaturation (% C20-22 polyunsaturated fatty acids [r= 0.463, P < 0.001], unsaturation index [r= -0.369, P < 0.01]), a number of individual fatty acids and with delta5 desaturase activity (r= 0.451, P < 0.001). pFAT (range 14-53%) correlated with a number of individual fatty acids and delta5 desaturase activity (r= -0.610, P < 0.0001). Indices of elongase activity (r= -0.467, P < 0.001), and delta9 desaturase activity (r= 0.332, P < 0.05) were also related to pFAT but not insulin action. The results demonstrate that delta5 desaturase activity is independently related to both insulin resistance and obesity. While determining the mechanisms underlying this relationship is important for future investigations, strategies aimed at restoring "normal" enzyme activities, and membrane unsaturation, may have therapeutic importance in the "syndromes of insulin resistance."
Partus ancillae, fetus pecudis e il principio del commodum (2012)

La ricerca si occupa della questione, spesso dibattuta in passato ma in misura minore nei tempi recenti, se possa valere per il partus ancillae il principio conceptus pro iam nato habetur, quotiens de commodis ipsius partus quaeritur (espresso in D. 1.5.7 e 50.16.231) nei casi in cui non si discuta della sua libertà ma solo dell'appartenenza ad uno o un altro proprietario
Oxygen vacancies and intense luminescence in manganese loaded Zno microflowers for visible light water splitting (2015)

ZnO nanorods and Mn/ZnO microflowers with nano-sized petals exhibit singly ionized oxygen vacancies, V. This is strongly supported by a green photoluminescence emission at 2.22 eV and an EPR g value of 1.953, both of which are suppressed greatly after annealing in an oxygen atmosphere. A strong red emission observed during exposure to X-rays reveals the presence of F(+) centres as a consequence of the V. Mn/ZnO displayed enhanced H2 generation with visible light exposure, when compared to pure ZnO and annealed Mn/ZnO in the visible region, which directly correlated with the oxygen vacancy concentration. There is an interesting correlation between the intensities of the EPR lines at the g-value of 1.953 due to the oxygen vacancies, the intensity of light emitted from the exposure to X-rays, the intensity of the photoluminescence due to oxygen vacancies and the quantity of H2 produced by the photocatalytic effect when comparing the three different nanomaterials, viz. pure ZnO, Mn/ZnO before and after annealing, all having been made exactly by the same methodologies.
Emerging Roles for Eph Receptors and Ephrin Ligands in Immunity (2019)

Eph receptors are the largest family of receptor tyrosine kinases and mediate a myriad of essential processes in humans from embryonic development to adult tissue homeostasis through interactions with membrane-bound ephrin ligands. The ubiquitous expression of Eph receptors and ephrin ligands among the cellular players of the immune system underscores the importance of these molecules in orchestrating an optimal immune response. This review provides an overview of the various roles of Eph receptors and ephrin ligands in immune cell development, activation, and migration. We also discuss the role of Eph receptors in disease pathogenesis as well as the implications of Eph receptors as future immunotherapy targets. Given the diverse and critical roles of Eph receptors and ephrin ligands throughout the immune system during both resting and activated states, this review aims to highlight the critical yet underappreciated roles of this family of signaling molecules in the immune system.
From laboratory to clinic: noradrenergic enhancement of physical therapy for stroke or trauma patients. (1997)

Research on treatments for cerebral stroke or traumatic brain injury (TBI) has focused on limiting the cascade of toxic pathologic events leading to primary and secondary neuronal death occurring early after injury. This approach of rescuing compromised neurons or "sparing" has had limited clinical success, and the very short therapeutic window limits therapeutic potential. This hopeless attitude for improving the status of patients weeks or a month after stroke may change with the accumulating data on the noradrenergic strategy. This approach uses any of a family of drugs to increase central levels of noradrenaline (NA), which, combined with physical therapy (NA/PT), produces an enduring alleviation of some symptoms of cortical injury. Importantly, beneficial effects of short-term treatment endure even when treatment is initiated a month after stroke. Long-term follow-up showed that the beneficial effect is robust, producing recovery to an ultimately higher level of hemiplegia recovery. Data from TBI patients indicate enhanced functional recovery of cognitive deficits using a similar intervention. The NA hypothesis for the beneficial effect is complemented with data from laboratory as well as from stroke patients that show slowing of recovery is produced by commonly prescribed drugs blocking alpha 1 NA receptors and other drugs shown harmful to recovery in animal models. Preliminary data suggest these beneficial and harmful effects on recovery may be extended to more complex functions such as aphasia. These findings are interpreted as NA modulation of a diaschisis, or remote functional depression in the cerebellum resulting from cortical injury.
Construction of oncogenetic tree models reveals multiple pathways of oral cancer progression (2009)

Oral cancer develops and progresses by accumulation of genetic alterations. The interrelationship between these alterations and their sequence of occurrence in oral cancers has not been thoroughly understood. In the present study, we applied oncogenetic tree models to comparative genomic hybridization (CGH) data of 97 primary oral cancers to identify pathways of progression. CGH revealed the most frequent gains on chromosomes 8q (72.4%) and 9q (41.2%) and frequent losses on 3p (49.5%) and 8p (47.5%). Both mixture and distance-based tree models suggested multiple progression pathways and identified +8q as an early event. The mixture model suggested two independent pathways namely a major pathway with -8p and a less frequent pathway with +9q. The distance-based tree identified three progression pathways, one characterized by -8p, another by -3p and the third by alterations +11q and +7p. Differences were observed in cytogenetic pathways of node-positive and node-negative oral cancers. Node-positive cancers were characterized by more non-random aberrations (n = 11) and progressed via -8p or -3p. On the other hand, node-negative cancers involved fewer non-random alterations (n = 6) and progressed along -3p. In summary, the tree models for oral cancers provided novel information about the interactions between genetic alterations and predicted their probable order of occurrence.
Preparation and Evaluation of<i>P-tert</i>-Butyl-calix[8]arene-bonded Silica Stationary Phase for High Performance Liquid Chromatography (2000)

ABSTRACT A new p-fert-butyl-calix[8]arene-bonded silica gel stationary phase was synthesized through heterogeneous functionalisation of suspended porous silica. A characterization of its structure was carried out by using elemental analysis, FTIR and 13C solid state NMR spectroscopy. Chromatographic performance of the new packing material was investigated by employing polycyclic aromatic hydrocarbons (PAHs) as probes and using methanol-water as mobile phase. The investigations show that the new stationary phase behaves as a reversed phase stationary phase. The liquid chromatographic separation of PAHs solutes on the new bonded phase was compared with that on a p-tert-butyl-calix[4]arene-bonded silica stationary phase. The new p-tert-butyl-calix[8]arene-bonded phase exhibited higher retention and better separation selectivity, although the carbon content and coverage of the new packing material was lower than that of the p-tert-butyl-calix[4]arene bonded silica stationary phase. A possible retention mechanism for the new packing material was also proposed.
New therapeutic uses for an old family of drugs: travels of a dental researcher from the lab to the University’s office of technology transfer and beyond (1996)

The authors, including an academic-inventor, the director of the University’s tech-transfer office, and the CEO of a “start-up” pharmaceutical company based on the professor’s (and his colleague’s) inventions, relate the history and current status of
Affect and machine design: Lessons for the development of autonomous machines (2003)

Human beings have evolved a rich and sophisticated set of processes for engaging with the world in which cognition and affect play two different but equally crucial roles. Cognition interprets and makes sense of the world. Affect evaluates and judges, modulating the operating parameters of cognition and providing warning of possible dangers. The study of how these two systems work together provides guidance for the design of complex autonomous systems that must deal with a variety of tasks in a dynamic, often unpredictable, and sometimes hazardous environment.
Donkey (1965)

Donkey Get access F. C. H. F. C. H. Search for other works by this author on: Oxford Academic Google Scholar Notes and Queries, Volume s3-VII, Issue 160, 21 January 1865, Page 66, https://doi.org/10.1093/nq/s3-VII.160.66c Published: 21 January 1965
A high-performance, miniaturized X-band active mixer for DBS receiver application with on-chip IF noise filter (1990)

A GaAs monolithic microwave integrated circuit (MMIC) dual-gate FET active mixer at X-band is described that is designed for direct broadcast satellite (DBS) applications. All of the components of the mixer, including biasing circuitry, RF, LO, and IF matching networks, as well as the IF noise filter, are implemented monolithically into a 25-mil*30-mil area. The design was process tolerant, and layout was compact for manufacturability and low cost. The mixer was integrated monolithically into a complete single-chip DBS low-noise block (LNB) converter. The active mixer has a conversion gain of 5.5 dB and a single-sideband noise figure of 8.5 dB. The circuit is manufactured using a 0.5- mu m gate length, buried p/sup -/ depletion mode MESFET process without substrate-through via holes.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Estimating genomic instability mediated by Alu retroelements in breast cancer (2009)

Alu-PCR is a relatively simple technique that can be used to investigate genomic instability in cancer. This technique allows identification of the loss, gain or amplification of gene sequences based on the analysis of segments between two Alu elements coupled with quantitative and qualitative analyses of the profiles obtained from tumor samples, surgical margins and blood. In this work, we used Alu-PCR to identify gene alterations in ten patients with invasive ductal breast cancer. Several deletions and insertions were identified, indicating genomic instability in the tumor and adjacent normal tissue. Although not associated with specific genes, the alterations, which involved chromosomal bands 1p36.23, 1q41, 11q14.3, 13q14.2, occurred in areas of well-known genomic instability in breast and other types of cancer. These results indicate the potential usefulness of Alu-PCR in identifying altered gene sequences in breast cancer. However, caution is required in its application since the Alu primer can produce non-specific amplification.
Elastic fibers in elastofibroma dorsi by fine‐needle aspiration (2013)

Fine-needle aspiration (FNA) features of elastofibroma dorsi (EFD) in a 56-year-old woman were evaluated. The patient presented with 5 cm soft tissue mass located between the inferior part of scapula and the chest wall. FNA smears were hypercellular, characterized by a mixture of uniform spindle cells, mature adipocytes, and collagen tissue fragments in varying proportions. The cytological findings included abundant degenerated elastic fibers presented as linear ("braid-like") and globular bodies with shell-like and stellate appearances with serrate borders, permitting a diagnosis of EFD. Occurrence of degenerated elastic fibers in FNA smears of elastofibroma is a highly diagnostic sign in the typical clinical setting and eliminates the need for preoperative histological examination.
The 'Desert' Society in Languedoc (1686-1704) as Popular Culture and the Roots of French Quakerism (2005)

The 'Desert' society in Cevennes, Languedoc, was an offshoot of the persecution of French Protestants by Louis XIV. The clandestine assemblies that met in the ravines gave rise to lay ministry, as the Revocation of the Edict of Nantes (1685) had forced professional ministers to flee abroad. At first, Predicants replaced ministers, then Prophets and Prophetesses in turn replaced the killed Predicants. The 'Desert' society gave birth to a popular culture. At the end of the seventeenth century, the Protestants' resistance was peaceful, but as persecutions grew, the Camisard war broke out in 1702. But a minority of Prophets refused violence, even in self-defence, as a solution to the Protestants' problems. They gathered in the Vaunage valley, around Congenies, near Nimes. Their spiritual descendants met British Friends in 1785, and joined the Religious Society of Friends in 1788. They also belonged to the popular culture of the 'Desert' society.
Observations on the use of a medium detecting β-glucuronidase activity and lactose fermentation for the simultaneous detection of Escherichia coli and coliforms (1994)

A study of the use of a recently described single membrane medium for the simultaneous enumeration of Escherichia coli and coliforms has shown similar E. coli confirmation rates (92%) for both membrane lauryl sulphate broth (MLSB) and membrane lactose glucuronide agar (mLGA). Of the presumptive E. coli examined, a higher proportion of those examined from MLSB subsequently produced acid and gas from lactose peptone water and indole from tryptophan than on mLGA. These results differ in some respects from those presented in the original paper and may therefore be of interest to those workers involved in the detection of E. coli in water. Further investigation showed that mLGA which has been stored under aerobic conditions was less efficient than freshly‐prepared medium in recovering coliforms and that the size of the colonies obtained on stored medium was sometimes much smaller than those found on freshly‐prepared medium.
Comparative Analysis of Space Vector Pulse-Width Modulation and Third Harmonic Injected Modulation on Industrial Drives. (2012)

This paper presents a detailed analysis of the comparative advantage of space vector pulse width modulation (SVPWM) over the existing third order harmonic injected pulse width modulation. The MATLAB/SIMULINK simulation results obtained from the direct application of 3-level voltage source inverter using SVPWM and third harmonic injected modulation drive strategy on 10 Horse Power, 400 volts,50Hz induction motor are also presented in this work with values of their respective total harmonic distortions been compared. The analysis and results obtained from this work will be very useful in the study of multi-level pulse-width modulation based technique especially in the industrial drive applications. This work will also help in determining the most efficient modulation strategy that has an acceptable performance with appreciable reduction in the magnitudes of harmonic distortion obtained during modulation which leads to optimum performance index.
Genetic Analysis of the Bone Morphogenetic Protein-Related Gene, gbb, Identifies Multiple Requirements During Drosophila Development (1999)

We have isolated mutations in the Drosophila melanogaster gene glass bottom boat (gbb), which encodes a TGF-beta signaling molecule (formerly referred to as 60A) with highest sequence similarity to members of the bone morphogenetic protein (BMP) subgroup including vertebrate BMPs 5-8. Genetic analysis of both null and hypomorphic gbb alleles indicates that the gene is required in many developmental processes, including embryonic midgut morphogenesis, patterning of the larval cuticle, fat body morphology, and development and patterning of the imaginal discs. In the embryonic midgut, we show that gbb is required for the formation of the anterior constriction and for maintenance of the homeotic gene Antennapedia in the visceral mesoderm. In addition, we show a requirement for gbb in the anterior and posterior cells of the underlying endoderm and in the formation and extension of the gastric caecae. gbb is required in all the imaginal discs for proper disc growth and for specification of veins in the wing and of macrochaete in the notum. Significantly, some of these tissues have been shown to also require the Drosophila BMP2/4 homolog decapentaplegic (dpp), while others do not. These results indicate that signaling by both gbb and dpp may contribute to the development of some tissues, while in others, gbb may signal independently of dpp.
Current Technologies for Sludge Treatment and Disposal (1996)

Abstract This paper reviews the current sludge technologies and discusses likely future trends associated with those technologies. It describes the role of thickening, dewatering, pasteurization, stabilization, thermal destruction and product enhancement to satisfy environmental standards. Reference is made to technologies which, for decades, have been associated with sewage sludge but where market conditions have forced R and D initiatives to be introduced and commercialized.
Synthesis and evaluation of novel N–H and N-substituted indole-2- and 3-carboxamide derivatives as antioxidants agents (2007)

We have previously reported on the synthesis of novel indole derivatives where some compounds showed significant antioxidant activity. Here, we report the synthesis of novel N-H and N-substituted indole-2- and 3-carboxamide derivatives and investigated their antioxidant role in order to identify structural characteristics responsible for activity. Although all compounds showed a strong inhibitory (95-100%) effect on superoxide anion (SOD) only compounds 4, 5 and 6 showed simliar potency for the inhibition of lipid peroxidation (81-94%) which revealed that compounds 4, 5 and 6 possessed highly potent antioxidant properties. Substitution in the 1-position of the indole ring caused the significant differences between the activity results regarding lipid peroxidation inhibition.