gebhart/patrepeval huggingface dataset:
Water-Mediated Cooperative Migration of Chemisorbed Hydrogen on Graphene (2014)

The kinetics associated with the migration of chemisorbed hydrogen on a graphene sheet is studied using density-functional theory. Chemisorbed H atoms interact strongly through the carbon sheet and each chemisorbed H atom must form a pair with a H atom bound on the opposite side of the sheet in order to lower the energy with respect to the free H2 state. The two H atoms in a pair are correlated and migrate cooperatively. Because of the strong C-H bonds, the barrier to H cooperative migration is higher than 2.0 eV. However, when mediated by H2O molecules, the barrier can be reduced to less than 0.8 eV. The H pairing up leads to distinctive behavior of graphene hydrogenation, different from H chemisorption on a graphite surface. This study also demonstrates the superior effectiveness of water activation of C-H bonds and uncovers the mystery of fast kinetics of H spillover [Y. W. Li and R. T. Yang, J. Am. Chem. Soc. 128, 8136 (2006).
Platinum(II)–Gadolinium(III) Complexes as Potential Single‐Molecular Theranostic Agents for Cancer Treatment (2014)

Abstract Theranostic agents are emerging multifunctional molecules capable of simultaneous therapy and diagnosis of diseases. We found that platinum(II)–gadolinium(III) complexes with the formula [{Pt(NH 3 ) 2 Cl} 2 GdL](NO 3 ) 2 possess such properties. The Gd center is stable in solution and the cytoplasm, whereas the Pt centers undergo ligand substitution in cancer cells. The Pt units interact with DNA and significantly promote the cellular uptake of Gd complexes. The cytotoxicity of the Pt–Gd complexes is comparable to that of cisplatin at high concentrations (≥0.1 m M ), and their proton relaxivity is higher than that of the commercial magnetic resonance imaging (MRI) contrast agent Gd–DTPA. T 1 ‐weighted MRI on B6 mice demonstrated that these complexes can reveal the accumulation of platinum drugs in vivo. Their cytotoxicity and imaging capabilities make the Pt–Gd complexes promising theranostic agents for cancer treatment.
Staphylococcal Enterotoxin Superantigens (1991)

Staphylococcal enterotoxins (SE) are a family of structurally related proteins that are produced by Staphylococcus aureus. They play a role in the pathogenesis of food poisoning and are the most potent activators of T lymphocytes known. The receptors for SE on antigen-presenting cells are major histocompatibility complex class II molecules. Recent studies have shown that a complex of SE and major histocompatibility complex class II molecules is required for binding to the variable region of the T cell antigen receptor beta-chain. SE mitogenic activity is dependent on induction of interleukin 2, which may be intimately involved in the mechanism of SE toxicity. The minor lymphocyte-stimulating "endogenous" self-superantigen has recently been shown to be a retroviral gene product, so that this too is apparently a microbial superantigen. An understanding of the mechanism of action of these microbial superantigens has implications for normal and pathological immune functions.
Intensive hypermethylation of the CpG island of Ras association domain family 1A in hepatitis B virus-associated hepatocellular carcinomas. (2003)

HCC has the highest incidence of promoter methylation of RASSF1A among all malignancies yet reported suggesting that hypermethylation of the CpG island promoter of RASSF1A may play an important pathological role in this tumor.
Open Source Development Process: a Review. (2006)

This paper presents a review of the Open Source development process from the point of view of the involvement of the developers in the production process. The study focuses on how developers contribute to projects in terms of involvement, size and kind of their contribution. Data have been collected from different kinds of open source projects and the results show that the general behavior is the same, even if projects and people are different.
Electro-Optic Sampling of High Speed Nonlinear Devices (1993)

Get PDF Email Share Share with Facebook Tweet This Post on reddit Share with LinkedIn Add to CiteULike Add to Mendeley Add to BibSonomy Get Citation Copy Citation Text K. W. Chang and W. V. Sorin, "Electro-Optic Sampling of High Speed Nonlinear Devices," in Ultrafast Electronics and Optoelectronics, J. Shah and U. Mishra, eds., Vol. 14 of OSA Proceedings Series (Optica Publishing Group, 1993), paper I3. Export Citation BibTex Endnote (RIS) HTML Plain Text Citation alert Save article
Fluorescent lamp inverters using charge pump and partial smoothing capacitors (2002)

A highly efficient RF suppression circuit for fluorescent lamp inverters based on charge pump and partial smoothing capacitors is proposed. The circuit consists of a pumping capacitor, a partial smoothing capacitor and a control switch. The pumping capacitor is of comparatively small capacitance and the control switch operates to ensure that the pumping capacitor charging current is proportional to the AC power supply voltage even across the interval where the AC voltage is near zero. Effective use of current charging reduces the RF harmonic components in the supply current and improves the power factor. The charging voltage of the pumping capacitor (Vcp) and the charging voltage of the partial smoothing capacitor (Vch) together effect inverter driving of the lamp circuit. When the lamp starts, the control switch provides the high voltage, Vcp+Vch. After the lamp has started, Vcp and Vch are switched in alternation. During the period in which the partial smoothing capacitor is charging, the time constants of the choke coil at the rectifier circuit input and the partial smoothing circuit are optimized, while use of the charging voltage of the pump capacitor prevents the sudden appearance of a charging current at the input. Test circuits exhibited a power factor of 97.4% (well above the 85% rating), and the third to eleventh harmonics were at about half of the rated values, demonstrating the feasibility of a high-power-factor low-RF inverter.
The hydrogen sulfide donor IK‐1001 stimulates neovascularization and improves wound healing (2008)

Here we studied the effects of the novel biological mediator hydrogen sulfide (H2S) on angiogenesis and wound healing. We have utilized IK‐1001, an aqueous formulation of H2S. Treatment of chicken chorioallantoic membranes with H2S (0.24–240 pmol/egg) increased vascular length. In vitro, incubation of human umbilical vein endothelial cells with H2S (6 uM to 600 uM concentration) promoted cell growth. In addition, treatment of the cells with H2S (60 uM) increased their migration and capillary morphogenesis on matrigel. We have next tested the potential effect of hydrogen sulfide in a wound healing model. Rats received a 30% total body surface area dorsal full‐thickness scald burn under deep anesthesia. Starting at 48h post burn, the animals received daily subcutaneous injections at four equally spaced sites in the transition zone between burn eschar and healthy tissue. IK‐1001 (0.1 mg per injection) or saline control was used at each time point. After four weeks, the burn eschar was removed and the remaining wound area as well as the degree of re‐epithelialization determined. Re‐epithelialization was improved in the presence of hydrogen sulfide (24±2% vs. 16±5%, p<0.02). Our results demonstrate the pro‐angiogenetic and wound healing promoting effects of hydrogen sulfide.
Tissue Specific Modulation of cyp2c and cyp3a mRNA Levels and Activities by Diet-Induced Obesity in Mice: The Impact of Type 2 Diabetes on Drug Metabolizing Enzymes in Liver and Extra-Hepatic Tissues (2017)

Various diseases such as type 2 diabetes (T2D) may alter drug clearance. The objective of this study was to evaluate the effects of T2D on CYP450 expressions and activities using high-fat diet (HFD) as a model of obesity-dependent diabetes in C57BL6 mice. The cyp450 mRNA expression levels for 15 different isoforms were determined in the liver and extra-hepatic tissues (kidneys, lungs and heart) of HFD-treated animals (<i>n</i> = 45). Modulation of cyp450 metabolic activities by HFD was assessed using eight known substrates for specific human ortholog CYP450 isoforms: in vitro incubations were conducted with liver and extra-hepatic microsomes. Expression levels of cyp3a11 and cyp3a25 mRNA were decreased in the liver (>2-14-fold) and kidneys (>2-fold) of HFD groups which correlated with a significant reduction in midazolam metabolism (by 21- and 5-fold in hepatic and kidney microsomes, respectively, <i>p</i> < 0.001). HFD was associated with decreased activities of cyp2b and cyp2c subfamilies in all organs tested except in the kidneys (for tolbutamide). Other cyp450 hepatic activities were minimally or not affected by HFD. Taken together, our data suggest that substrate-dependent and tissue-dependent modulation of cyp450 metabolic capacities by early phases of T2D are observed, which could modulate drug disposition and pharmacological effects in various tissues.
Photonic crystal waveguides as discrete systems (2003)

Photonic crystals (PCs) are regarded as a promising and variable material base for a future photonic integration. Here we present a much simpler mathematical description, which often allows for analytical solutions. We start from the Bloch-modes of the unperturbed PCW. Using a kind of reciprocity theorem we obtain a set of evolution equations to describe the spatial-temporal evolution of the amplitudes of these Bloch-modes in the presence of arbitrary perturbations. Another important result of the reciprocity theorem is a new orthogonality relation for Bloch-modes, which allows to derive analytical expressions to quantify the coupling between PCWs and conventional waveguides. Reflection coefficient between two consecutive PCWs determined by means of the theory of a strongly coupled discrete system is presented.
Using fine grain multithreading for energy efficient computing (2007)

We investigate extremely fine-grain multithreading as a means for improving energy efficiency of single-task program execution.Our work is based on low-overhead threads executing an explicitly parallel program in a register-sharing context. The thread-based parallelism takes the place of instruction-level parallelism, allowing us to use simple and more energy-efficient in-order pipelines while retaining performance that is characteristic of classical out-of-order processors. Our evaluation shows that in energy terms, the parallelized code running over in-order pipelines can outperform both plain in-order and out-of-order processors.
Mediastinal Synovial Sarcoma (2009)

Synovial sarcoma of the mediastinum is a rare neoplasm that has overlapping histological and immunophenotypic features with other tumors in the differential diagnosis. We describe a case of this disease. The tumor was located at the right side of the pericardium, where an FDG-PET scan showed an uptake. It was resected, a resection which was complicated by the necessity of partially resecting the pericaridium and right middle lobe which were invaded by the tumor. The doubling time of the main tumor was 11.8 days. The margin of the resected specimen was tumor-free both macro- and microscopically. Reverse transcription-PCR confirmed the diagnosis of synovial sarcoma. The patient rejected chemotherapy or radiation therapy, and had recurrent tumors only one month after the operation. Finally, she opted to have only palliative care and died 79 days after the operation.
ChemInform Abstract: AZIDOMETHYL PHENYL SULFIDE. A SYNTHON FOR NH2 (1981)

Abstract Mit Hilfe der Titelverbindung (II) läßt sich die NHz‐Gruppe, ausgehend von Grignardverbindungen wie (I) oder entsprechenden Organo‐Li‐Derivaten von Arenen wie (V), einführen; durch Hydrolyse der prim. gebildeten (z.T.
EPITHELIOID ANGIOMYOLIPOMA OF THE KIDNEY (2009)

A 37-year-old female was referred to our department for a renal mass which was incidentally found during a medical check-up. She had no history of tuberous sclerosis. Computed tomography and magnetic resonance imaging showed a 1.5-cm enhancing mass at the lower pole of the left kidney. An open partial nephrectomy was performed for a pre-operative diagnosis of renal cell carcinoma. Pathological examination revealed sheets of large polygonal epithelioid cells that showed positive immunostaining for HMB-45, which confirmed the diagnosis of an epithelioid angiomyolipoma. The patient remained free of recurrent or metastatic disease at 3 months of follow-up. Epithelioid angiomyolipoma is a recently identified variant of angiomyolipoma, which is sometimes associated with aggressive clinical behavior including local recurrence and metastasis. We present this case and review the literature concerning this unusual disorder.
Real time landscape modelling and visualization (2007)

With the rapid development of information and communication technology and widely spreading of internet, digital landscape becomes a high topic recently. This paper presents a landscape modeling- and visualizationssystem. The first part of this paper focuses on the real time 3D-model- lingsprocess out of large point-clouds. Diverse experiments have been done on the reconstruction of various famous regions of Bavaria with tourist features. And the second part concentrates on the interactive online visualizationssystem for massive meshes. To enable an efficient interactive online visualization of these large meshes, we convert them firstly with a multi-resolution hierarchy, and then display them progressively. As a preprocessing for the inter-active rendering, we generate a hierarchical tree of bounding spheres from triangle meshes and write it to disk. It will be used for view frustum culling, backface culling and level-of-detail control. We use a recursive algorithm for display. And the traverse-depth in the tree is decided by the projected size of the current node on the screen. By an interactive rendering, once the user stops moving the mouse, the scene will be redrawn with successively smaller thresholds until a size of one pixel is reached.
Committee Reports, October 2007 (2008)

Reports from the Executive Committee, the Division Business Meeting, the Journal of Chemical Education, the Examinations Institute, and the ACS Council Meeting, are published. Volunteers and awards are celebrated. The 20th annual BCCE meeting is introduced and a call for papers is announced.
Fiber size, type, and myosin heavy chain content in rhesus hindlimb muscles after 2 weeks at 2 G. (2002)

Our hypothesis was rejected. The changes in the proportion of fibers expressing type I MHC are the reverse of that expected with chronic loading of extensors and, paradoxically, are similar to changes observed with chronic unloading, such as occurs during spaceflight, in this primate model. The data are consistent with the observed decrease in total daily activity levels.
33. Commission de la Statistique Stellaire (1939)

The following report, which has been drawn up partly on the basis of the reports of the members of the Commission, touches briefly and without any attempt at completeness a few points of the recent developments in certain important fields falling within the domain of the Commission.
Identification of DNA markers linked to the Me3 gene controlling resistance to root-knot nematodes in pepper (Capsicum annuum) (1996)

International audience
A graph optimization approach for motion estimation using inertial measurement unit data (2018)

This study presents a novel approach for processing motion data from a six-degree-of-freedom inertial measurement unit (IMU). Trajectory estimation through double integration of acceleration measurements results in the generation and accumulation of multiple errors. Existing IMU-based measurement methods often use constrained initial and final states to resolve these errors. The constraints on the initial and final states lead to a uniform distribution of the accumulated errors throughout the calculated trajectory so that they cancel each other. We develop a generalized method that can incorporate the constraints from the measurements of intermediate states. The proposed approach is inspired by graph-based simultaneous localization and mapping processes from robotics research. We tested the proposed method with simulated and actual IMU data and found that our method estimates trajectories more accurately than conventional methods with acceptably higher computational costs.
Image Enlargement Based on Proportional Salient Feature (2014)

Abstract This paper proposes an image enlargement method that produces proportional salient content of image magnification. To obtain the proportional salient image content: first, we enlarge the source image to the high size of the target image using uniform enlarging. Second, we slice the image into sections from top to bottom following the minimum energy and detect the salient feature of the image. Third, we enlarge the slice of the image region that does not containthe salient feature of the image to the full size of the target image. The proposed method has been tested in several images, such as akiyo, butterfly, cameraman, canoe, dolphin, and parrot. The experimental results show that the proposed method results in a proportional content for image enlargement in the different ratios compared with the comparison method.
ChemInform Abstract: SYNTHESIS AND CONFORMATIONAL ANALYSIS OF ISOMERIC 3‐PROPANANILIDOTROPANES (1977)

Abstract Synthesis and Conformational Analysis of Isomeric 3‐Propananilidotropanes.
Preparation and Characterization of a New Tl-1222 Layered Cobaltite (2002)

The preparation and the characterization of a new layered cobaltite of formula Tl0.900±0.005Sr3LaCo2O8.60±0.07 is described. This oxide is isostructural with the so-called 1222 member of the homologous cuprate series (Space Group I4/mmm). Oxygen vacancies are rather located in thallium layers or in apical positions. The six oxygen atoms surrounding the cobalt form an elongated octahedron of C4v symmetry. The magnetic susceptibility exhibits a complex behavior attributed to a change of the cobalt effective moment with temperature. The compound is a semiconductor. The temperature dependencies of the electrical conductivity and of the thermoelectric power are interpreted in terms of hopping and variable range hopping at low temperature. The behavior of this 1222 cobaltite is compared to that of the 1201-TlSr2CoO5, paying a particular attention to the interplay of electronic properties with structural distortion, disordering, and cobalt mixed valence. Präparation und Charakterisierung eines neuen Tl-1222 Schicht-Cobaltits Präparation und Charakterisierung eines neuen Schicht-Cobaltits der Formel Tl0, 900±0, 005Sr3LaCo2O8, 60±0, 07 wird beschrieben. Dieses Oxid ist isostrukturell mit dem sogenannten 1222-Mitglied der homologen Cuprat-Reihe (Raumgruppe I4/mmm). Suerstofffehlstellen sind eher in Thalliumschichten oder in apikalen Positionen lokalisiert. Die sechs Sauerstoffatome, die das Cobaltatom umgeben, bilden ein gestrecktes Oktaeder mit C4v-Symmetrie. Die magnetische Suszeptibilität zeigt ein komplexes Verhalten aufgrund der Abhängigkeit des effektiven Moments des Cobalts von der Temperatur. Die Verbindung ist ein Halbleiter. Die Temperaturabhängigkeit der elektrischen Leitfähigkeit sowie der Thermokraft werden als hopping- und variable-range hopping-Prozesse bei niedriger Temperatur interpretiert. Das Verhalten dieses 1222-Cobaltits ist ähnlich dem des 1201-TlSr2CoO5 unter besonderer Beachtung der Wechselwirkung der elektronischen Eigenschaften mit strukturellen Verzerrungen, Fehlordnungen und der gemischten Valenz der Cobaltatome.
Assessment of GNSS signal acquisition sensitivities for indoor and urban scenarios (2010)

Signals of Galileo and modernized GPS will provide a new possibility in the next five years that will enable to overcome current limitations in indoor/urban environments. With modernization of GPS L1C, L2C, L5 and full deployment of Galileo, E1b, c, E5a, b, E6 signals will be available. It is therefore of major interest to assess new capabilities of the incoming GNSS signals and their potential for the location based and emergency services in GNSS enabled mobile phone or PDA. In this paper, the acquisition performance of the available GPS and Galileo signals are evaluated related to the receiver sensitivity and the computational complexity within different scenarios. By using a weighting evaluation, we show that GPS L5 pilot signal gives the optimum performance among available signals.
Sociologie économique et politiques publiques (2019)

Après que le regard des sociologues s’est, durant une cinquantaine d’années, occupé à fragmenter les objets économiques en autant de champs spécialisés (les professions, le travail, les organisations, etc.), la sociologie économique a connu, à compter du début des années 1970 aux États-Unis et des années 1990 en France, une forme de renaissance : à la faveur de travaux séminaux (Granovetter, 1974 ; Garcia, 1986), elle s’est rapidement imposée comme un espace intellectuel au dynamisme exceptionnel, reconnu et structuré par la publication de traités et d’ouvrages de synthèse (Smelser et Swedberg, 2005 ; Steiner et Vatin, 2009 ; François, 2008).\n\nIci résumée à grands traits, la trajectoire historique de la sociologie économique s’est accompagnée d’une renégociation permanente de certaines frontières disciplinaires : avec l’économie modélisatrice au premier chef, mais aussi avec les différentes branches de l’économie hétérodoxe, des sciences de gestion ou de la science politique. L’objet de cet article est précisément d’explorer cette dernière marge disciplinaire, en nous attachant à l’arpenter non sur le territoire qui pourrait sembler le plus évident (celui où pourraient dialoguer sociologie économique et political economy [Hall et Soskice, 2001]), mais en évoquant l’articulation de la sociologie économique et de l’analyse des politiques publiques. Cette articulation prend un tour paradoxal : sociologie économique et analyse de l’action publique ont beaucoup à apprendre l’une de l’autre – pour l’essentiel, cependant, elles ne se parlent pas. [extrait des deux premiers paragraphes]
A NEW METHOD OF CALCULATING EVOLUTIONARY RATES OF PROTEINS APPLIED TO INSULIN AND C‐PEPTIDES (1974)

The optimal number of differences between sequences for phylogenetic studies is derived, and the developed theory is used to show that a sequenced peptide assumed to be duck proinsulin C‐peptide had the expected differences from the mammalian C‐peptides. The theory is used to separate the guinea pig insulin from other insulins, indicating that the pressure of selection on guinea pig insulin has been significantly lower than that on other insulins. Finally, calculation of the half‐life of a protein as a measure of the pressure of selection rather than the evolutionary rate constant is proposed.
Unit for monitoring and controlling the hall effect using labview (2008)

We assembled a Hall effect and electric conductivity measuring unit that allows the determination of transport properties in semiconductor and metal films, including the type and concentration of majority carriers and their mobility, from measurements of Hall voltage and current. It is clear that electrons are the charge carrier in metals, however some metals such as aluminum, zinc and cadmium among others exhibit a behavior that, according to the classical view, should be positive charge carriers (holes). In this paper we discuss Hall effect measurements in two types of materials: copper (Cu) and zinc (Zn). Results from measurements show that copper has a negative Hall coefficient RH = - (0.28 ± 0.01)◊10 -10 m 3/C and zinc has a positive coefficient RH = + (4.2 ± 0.2)◊10 -11 m 3/C. Our results agree with those reported in the scientific literature. Most of the textbooks on solid state physics do not mention explicitly the reason why some metals show a positive Hall coefficient. We discuss this fact based on their band structures.