gebhart/patrepeval huggingface dataset:
The Lesson of Supplementary Treatment with Chinese Medicine on Severe Laboratory-Confirmed SARS Patients (2006)

Chinese medicine (CM) has been used to control infectious diseases for thousands of years. In 2003 outbreaks of severe acute respiratory syndrome (SARS) occurred in China, Hong Kong and Taiwan. In view of the possible beneficial effect of CM on SARS, we conducted this study to examine whether CM is of any benefit as a supplementary treatment of SARS. Four severe laboratory-confirmed SARS patients received routine western-medicine treatment plus different supplementary treatment: CM A, CM B and CM C (placebo control). We reported the course of the cases in terms of changes in chest radiographic scores. Case 1 treated as a placebo control passed away on the 9th day after onset of disease. The other three cases treated with CM A or CM B survived. The initial findings seemed to indicate a favorable effect of CM on management of SARS. The findings need to be verified with a larger sample. Using CM as a supplementary treatment of severe SARS seems to indicate that natural herbal medicine can be used against avian influenza. Hence, such related experience or clinical trials should be taken into consideration when facing the possible outbreak of avian influenza in the future.
Feasibility of tracked electrodes for use in epilepsy surgery (2016)

Subdural electrode recording is commonly used to evaluate intractable epilepsy. In order to accurately record electrical activity responsible for seizure, electrodes must be positioned precisely near targets of interest, often indicated preoperatively through imaging studies. To achieve accurate placement, a large craniotomy is used to expose the brain surface. With the intent of limiting the size and improving the location of craniotomy for electrode placement, we examined magnetic tracking for localization of electrode strips. Commercially available electrode strips were attached to specialized magnetic tracking sensors developed by Medtronic plc. In a rigid phantom we evaluated the strips to determine the accuracy of electrode placement on targets. We further conducted an animal study to evaluate the impact of magnetic field interference during data collection. The measured distance between the physical fiducial and lead coil of the electrode strip was 1.32 ± 1.03mm in the phantom experiments. The tracking system induces a very strong signal in the electrodes in the Very Low Frequency, an International Telecommunication Union (ITU) designated frequency band, from 3 kHz to 30 kHz. The results of the animal experiment demonstrated both tracking feasibility and data collection.
Characterization of three monoclonal antibodies to membrane co-factor protein (MCP) of the complement system and quantification of MCP by radioassay (1991)

MCP is a widely distributed regulatory glycoprotein of the complement system which binds C3b and C4b and has factor I-dependent co-factor activity. Monoclonal antibodies raised to lymphocytes (E4.3), chorionic microvilli (GB24) and an embryonal carcinoma cell line (TRA-2-10) recognize MCP (CD46). GB24 inhibited both the binding of MCP to its ligand iC3 and co-factor activity; E4.3 and TRA-2-10 did not. The binding of GB24 to cells bearing MCP was not cross-inhibited by E4.3 or TRA-2.10, but TRA-2-10 blocked binding and displaced pre-bound E4.3. Using these antibodies, we developed a radioassay for quantifying the number of MCP molecules/cells. Human peripheral blood mononuclear (PBMC) and polymorphonuclear cells (PMN) had about 10,000 MCP cell; platelets had about 600/cell, and no MCP was found on erythrocytes. Neoplastic hematopoietic cell lines, of myelocytic and T lymphocytic origin, had several-fold more (20-60,000) molecules cell than peripheral blood cells or B cell lines (about 12,000). Malignant epithelial cell lines. HeLa (about 100,000/cell) and HEp-2 (about 250,000 cell) had the highest MCP expression of any cells examined. These monoclonal antibodies--especially GB24, which blocks MCP function--and the direct binding assay will facilitate the further analysis of the biology of this complement regulatory protein.
Emerging Risks in the Biodiesel Production by Transesterification of Virgin and Renewable Oils (2010)

Biodiesel is a very attractive biofuel because of its environmental benefits. However, despite its status as a safe substance, the production process can be hazardous because methanol or other flammable reactants, such as sodium methylate, can leave plants vulnerable to fire and explosion if not properly engineered and operated. However, further issues are emerging for the increasing capacity of plants, which have driven up on-site volumes of highly hazardous chemicals. Furthermore, some catastrophic accidents have occurred in very recent years in the glycerine neutralization phase. In this paper, insights of risks within this fairly new industry are presented. Heterogeneous catalysis seems to be the promising step for safer biodiesel productions.
Mechanistic Modes for Solid Carbon Conversion in High Temperature Fuel Cells (2010)

Progress in solid fuel utilization in fuel cells relies on devising effective delivery mechanisms for solid fuel and oxygen to the electrochemical reaction site. This paper provides a mechanistic overview of the different delivery modes and vehicles that have been adopted for engaging solid fuel and oxygen at the electrochemical interface to achieve efficient oxidation of carbon. Also, a "CO shuttle" mechanism is proposed to explain the operation and behavior of several direct carbon fuel cell (DCFC) approaches in or inert environments. This paper also introduces the operating principle and experimental results of a concept: the fluidized bed (FB) DCFC. It consists of a solid oxide fuel cell arrangement coupled to a Boudouard-type FB dry gasifier. A maximum power density of (or 4 W) was achieved at for the conversion of activated carbon in this FB-DCFC arrangement.
To the Peripheries of Mormondom: The Apostolic Around-the-World Journey of David O. McKay, 1920–1921 (2013)

Book Review| January 01 2013 To the Peripheries of Mormondom: The Apostolic Around-the-World Journey of David O. McKay, 1920–1921 To the Peripheries of Mormondom: The Apostolic Around-the-World Journey of David O. McKay, 1920–1921, Hugh J. Cannon and Reid L. Neilson. Gregory A. Prince Gregory A. Prince Search for other works by this author on: This Site Google Journal of Mormon History (2013) 39 (1): 216–218. https://doi.org/10.2307/24243750 Cite Icon Cite Share Icon Share Facebook Twitter LinkedIn MailTo Permissions Search Site Citation Gregory A. Prince; To the Peripheries of Mormondom: The Apostolic Around-the-World Journey of David O. McKay, 1920–1921. Journal of Mormon History 1 January 2013; 39 (1): 216–218. doi: https://doi.org/10.2307/24243750 Download citation file: Zotero Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All Scholarly Publishing CollectiveUniversity of Illinois PressJournal of Mormon History Search Advanced Search The text of this article is only available as a PDF. © 2013 Mormon History Association2013 Article PDF first page preview Close Modal You do not currently have access to this content.
Cell Wall Replication in <i>Escherichia coli</i> , Studied by Immunofluorescence and Immunoelectron Microscopy (1966)

Beachey, Edwin H. (National Institute of Allergy and Infectious Diseases, Bethesda, Md.), and Roger M. Cole. Cell wall replication in Escherichia coli, studied by immunofluorescence and immunoelectron microscopy. J. Bacteriol. 92:1245-1251. 1966.-Cell wall components of four different strains of Escherichia coli (B; B/r, try(-); O5; and O86:B7) were labeled with homologous fluorescent antibodies (FLG); the way the label was dispersed on further growth in media free of antibody was followed by fluorescence microscopy. Fluorescence diminished diffusely along longitudinal wall but remained bright at cell poles (or cross walls); newly formed cross walls did not fluoresce. In agreement, reverse labeling (preincubation in unlabeled antibody, followed by staining on the slide with homologous FLG) showed that stainability of longitudinal wall increased gradually and diffusely with increased time of incubation, whereas polar wall remained nonfluorescent or stained only faintly; newly formed poles (or cross walls), on the other hand, stained brightly. These observations were confirmed by electron microscopy, after immunoferritin labeling. Although the mode of cross-wall formation remained unclear, our findings refuted reported ideas of segmental or polar growth of cell wall in E. coli and supported the idea of wall replication by diffuse intercalation, as described for Salmonella.
Mapping of Protein-Protein Interactions of E. coli RNA Polymerase with Microfluidic Mechanical Trapping (2014)

The biophysical details of how transcription factors and other proteins interact with RNA polymerase are of great interest as they represent the nexus of how structure and function interact to regulate gene expression in the cell. We used an in vitro microfluidic approach to map interactions between a set of ninety proteins, over a third of which are transcription factors, and each of the four subunits of E. coli RNA polymerase, and we compared our results to those of previous large-scale studies. We detected interactions between RNA polymerase and transcription factors that earlier high-throughput screens missed; our results suggest that such interactions can occur without DNA mediation more commonly than previously appreciated.
MONOLITHIC SILICON BOLOMETERS COUPLED TO WAVEGUIDE (2001)

We have measured the performance of ion-implanted silicon bolometers developed for observations of faint astrophysical sources at millimeter wavelengths. These devices are mounted in waveguide to couple to a single mode of electromagnetic radiation. We measure optical coupling efficiencies of ~ 90 % across a full waveguide band. When cooled to 0.1 K and operated under low background conditions, the devices have a time constant of 1.5 – 4 ms and NEP ~ . They have a small cross-section to cosmic rays. We describe an application of these bolometers to a balloon-borne measurement of the 2.7 K cosmic microwave background radiation at frequencies between 65 and 170 GHz.
Search-Based SAT Using Zero-Suppressed BDDs (2002)

We introduce a new approach to Boolean satisfiability (SAT) that combines backtrack search techniques and zero-suppressed binary decision diagrams (ZBDDs). This approach implicitly represents SAT instances using ZBDDs, and performs search using an efficient implementation of unit propagation on the ZBDD structure. The adaptation of backtrack search algorithms to such an implicit representation allows for a potential exponential increase in the size of problems that can be handled.
Nitric oxide synthase-independent long-term potentiation in area CA1 of hippocampus (1993)

In order to elucidate the role of NO in LTP, we have investigated a biochemical effector of NO action at hippocampal synapses, guanylyl cyclase. We have observed that LTP-inducing stimuli elicit an increase in the activity of guanylyl cyclase, an effect blocked by inhibitors of NO synthase. Extracellular application of hemoglobin, which binds NO and thereby blocks its actions, also attenuated the increase in guanylyl cyclase activity. Taken together, these results provide direct biochemical evidence for an elevation of NO levels with LTP-inducing stimulation, and support the hypothesis that NO can function as a transcellular messenger in the hippocampus. These findings also implicate guanylyl cyclase as a target of NO and demonstrate that while NO is elevated with LTP-inducing stimuli, the activity of NO synthase is not necessary for induction of LTP by all stimulus paradigms.
The OSSA simulation environment: a supporting tool to transport safety evaluation and assessment (2002)

The OSSA project addresses the need to produce a user-friendly and meaningful traffic simulation environment to end-users. This will be achieved by the development of a standard OPEN simulation framework that will provide interoperability among different simulation related applications and tools: UTC systems, dynamic O/D matrix, co-simulators (emissions), data sources: GIS, traffic data, etc. By using the OSSA simulation environment, transport planners, traffic engineers and decision makers will be able evaluate traffic management strategies in terms of safety and security, as well as to plan specific strategies for special or emergency events.
Abstract 1966: Comparison of Right Ventricular Strain and Strain Rate in Patients with Arrhythmogenic Right Ventricular Cardiomyopathy, Right Ventricular Outflow Tract Tachycardia, and Matched Controls (2007)

Background: Arrhythmogenic right ventricular cardiomyopathy (ARVC) is characterized by fibro-fatty replacement of RV myocardium leading to ventricular tachycardia and sudden death in otherwise healthy individuals. Diagnosis is challenging as there are no diagnostic tests with adequate accuracy. Current diagnosis of ARVC is made by the task force criteria. One of the main diagnostic dilemmas continues to be distinguishing ARVC from a relatively benign entity of right ventricular out flow tract tachycardia (RVOT VT). Assessment of myocardial strain and strain rate has been used to study patients with ischemic heart disease and has shown utility in identifying subtle myocardial dysfunction not detected by routine wall motion assessment. The goal of this study was to compare myocardial strain and strain rates in patients with ARVC, RVOT VT and matched controls. Methods: We prospectively enrolled 12 patients with ARVC (based on task force criteria), 10 with RVOT VT, and 22 age and gender matched controls. Echo studies (including tissue Doppler derived myocardial strain echocardiography) were performed with commercially available systems (GE, Vivid 7). Peak systolic RV myocardial strain and strain rate were measured at base, mid, and apical RV free wall and compared. Results: ARVC patients had significantly lower peak systolic RV strain compared to both RVOT VT patients and matched controls (Table ). There was also significantly lower peak systolic strain rate at the apical RV myocardium in patients with ARVC compared to both those with RVOT VT (p=0.02) and controls (p=0.01). Conclusions: Patients with ARVC have abnormally low RV systolic strain and strain rates when compared to matched controls as well as those with RVOT VT. This modality can be routinely used in assessing patients suspected of ARVC as it might assist in earlier diagnosis as well as help in distinguishing patients with ARVC from those with RVOT VT. P<0.05 compared to controls, † P<0.05 compared to RVOT VT group
Solution Self-Assembly of the Sophorolipid Biosurfactant and Its Mixture with Anionic Surfactant Sodium Dodecyl Benzene Sulfonate (2011)

The self-assembly in aqueous solution of the acidic (AS) and lactonic (LS) forms of the sophorolipid biosurfactant, their mixtures, and their mixtures with anionic surfactant sodium dodecyl benzene sulfonate, LAS, has been studied using predominantly small-angle neutron scattering, SANS, at relatively low surfactant concentrations of <30 mM. The more hydrophobic lactonic sophorolipid forms small unilamellar vesicles at low surfactant concentrations, in the concentration range of 0.2 to 3 mM, and transforms via a larger unilamellar vesicle structure at 7 mM to a disordered dilute phase of tubules at higher concentrations, 10 to 30 mM. In marked contrast, the acidic sophorolipid is predominantly in the form of small globular micelles in the concentration range of 0.5 to 30 mM, with a lower concentration of larger, more planar aggregates (lamellar or vesicular) in coexistence. In mixtures of AS and LS, over the same concentration range, the micellar structure associated with the AS sophorolipid dominates the mixed-phase behavior. In mixtures of anionic surfactant LAS with the AS sophorolipid, the globular micellar structure dominates over the entire composition and concentration range studied. In contrast, mixtures of LAS with the LS sophorolipid exhibit a rich evolution in phase behavior with solution composition and concentration. At low surfactant concentrations, the small unilamellar vesicle structure present for LS-rich solution compositions evolves into a globular micelle structure as the solution becomes richer in LAS. At higher surfactant concentrations, the disordered lamellar structure present for LS-rich compositions transforms to small vesicle/lamellar coexistence, to lamellar/micellar coexistence, to micellar/lamellar coexistence, and ultimately to a pure micellar phase as the solution becomes richer in LAS. The AS sophorolipid surfactant exhibits self-assembly properties similar to those of most other weakly ionic or nonionic surfactants that have relatively large headgroups. However, the more hydrophobic nature of the lactonic sophorolipid results in a more complex and unusual evolution in phase behavior with concentration and with concentration and composition when mixed with anionic surfactant LAS.
Characterization of buried photonic crystal waveguides and microcavities fabricated by deep ultraviolet lithography (2005)

We present results of the optical characterization of silicon photonic crystal waveguides and microcavities that are completely buried in a silicon dioxide cladding and are fabricated by deep ultraviolet (UV) lithography. The advantages of buried waveguides and deep UV lithography are discussed. Transmission spectra and loss factors for photonic crystal waveguides, as well as quality factors for resonant microcavities, are obtained. The observed characteristics are in good agreement with three-dimensional simulations.
ChemInform Abstract: EINE UNERWARTETE RK.‐AENDERUNG IM GLEICHGEWICHT ZWISCHEN S(N)2‐ UND E2‐RK. MIT FORMIAT UND OXALAT ALS NUCLEOPHILEN (1972)

Abstract Aus dem (zt)‐Hydroxy‐lacton (Ia) erhält man mit p‐Tosylchlorid das Derivat (Ib), das mit Tetrabutylammoniumacetat zum Acetat (IIb) neben dem Cyclopenten (III) reagiert.
Studies on Proteolytic Enzyme of the Cricket, Gryllulus taiwanemma Ohmachi (1965)

protease was isolated from the alimentary canal of crickets.
Global Measles and Rubella Laboratory Network Support for Elimination Goals, 2010–2015 (2016)

In 2012, the World Health Assembly endorsed the Global Vaccine Action Plan (GVAP)* with the objective to eliminate measles and rubella in five World Health Organization (WHO) regions by 2020. In September 2013, countries in all six WHO regions had established measles elimination goals, and additional goals for elimination of rubella and congenital rubella syndrome were established in three regions (1). Capacity for surveillance, including laboratory confirmation, is fundamental to monitoring and verifying elimination. The 2012-2020 Global Measles and Rubella Strategic Plan of the Measles and Rubella Initiative(†) calls for effective case-based surveillance with laboratory testing for case confirmation (2). In 2000, the WHO Global Measles and Rubella Laboratory Network (GMRLN) was established to provide high quality laboratory support for surveillance (3). The GMRLN is the largest globally coordinated laboratory network, with 703 laboratories supporting surveillance in 191 countries. During 2010-2015, 742,187 serum specimens were tested, and 27,832 viral sequences were reported globally. Expansion of the capacity of the GMRLN will support measles and rubella elimination efforts as well as surveillance for other vaccine-preventable diseases (VPDs), including rotavirus, and for emerging pathogens of public health concern.
Mechanistic Investigations of 1-Aminocyclopropane 1-Carboxylic Acid Oxidase with Alternate Cyclic and Acyclic Substrates (2006)

The behavior of three cyclic and three acyclic analogues of 1-aminocyclopropane-1-carboxylic acid (ACC) with ACC oxidase has been analyzed with regard to turnover rates, product distribution, and O(2) uncoupling. The cyclic analogues all form ethylene, and the acyclic analogues all undergo decarboxylation. The degree of uncoupling varies from almost none (ACC) to 21-fold (glycine), while turnover rates (k(cat)) are all within a factor of 4-fold of that of ACC. The aggregate data point toward a rate-determining formation of an activated iron-oxo intermediate, which partitions between amine oxidation and reductive uncoupling in a manner that is dependent on substrate structure.
Effects of γ Irradiation on the Structure of Ribonuclease<sup>*</sup> (1966)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTEffects of γ Irradiation on the Structure of Ribonuclease*Evelyn Slobodian and Martin FleisherCite this: Biochemistry 1966, 5, 7, 2192–2200Publication Date (Print):July 1, 1966Publication History Published online1 May 2002Published inissue 1 July 1966https://pubs.acs.org/doi/10.1021/bi00871a006https://doi.org/10.1021/bi00871a006research-articleACS PublicationsRequest reuse permissionsArticle Views27Altmetric-Citations10LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Opto-electrical characterization of infrared sensors based on carbon nanotube films (2010)

A large array of devices based on a carbon nanotubes film was realized. Electrical characterization by the transfer length method enables the determination of the sheet resistance, and contact resistance, which is extremely low. The resistance dispersion is shown to be due to the film non-uniformity, and is low enough to enable the realization of bolometer focal plane arrays. A decrease of the resistance with the temperature is observed and leads to a TCR of <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" overflow="scroll"> <mml:mo>−</mml:mo> <mml:mn>0.2</mml:mn> <mml:mtext>%</mml:mtext> <mml:msup> <mml:mtext>K</mml:mtext> <mml:mrow> <mml:mo>−</mml:mo> <mml:mn>1</mml:mn> </mml:mrow> </mml:msup> </mml:math> . The strong absorption of carbon nanotubes films in the mid infrared transmission band (3–5 μm and of 8–14 μm) enables us to demonstrate the first carbon nanotubes photo response for these wavelengths.
ChemInform Abstract: PYRIMIDIN‐DERIVATE UND VERWANDTE VERBINDUNGEN 68. MITT. RK. VON DIALKYLACYLPHOSPHONATEN MIT 1,3‐DISUBSTITUIERTEN BENZIMIDAZOLIUMHALOGENIDEN (1970)

Abstract Bei der Umsetzung der Benzimidazoliumsalze (I) mit den Acylphosphonaten (II) in Dimethylformamid und in Gegenwart von Triäthylamin entstehen bei 2 ‐ 3°C 1:1‐Addukte (III) oder Betaine (IV), deren Behandlung mit Alkali die entsprechenden 2‐Imidazolinone (V) oder ringgeöffnete N‐Formyl‐ Derivate (VI) liefert.