gebhart/patrepeval huggingface dataset:
Studies on the Metabolism of D-Amino Acid in Microorganisms (1956)

A new enzyme responsible for the oxidation of D-glutamic acid was obtained from the mycelium of Aspergillus ustus strain f isolated from the soil. Many properties of this enzyme in the state of dried cell or crude extract were studied. The enzyme preparation strongly oxidizes D-glutamie-and D-aspartic acids but does not affect any other DL-amino acids at all. A new micro-determination method for D-glutamic acid has been devised by means of this enzyme.
Microcavity effects in a spin-coated polymer two-layer system (1995)

We report on the design and the optical properties of a spin-coated multilayer organic microcavity. Tri(stilbene)amine blended with polysulfone as the first layer and an oxadiazole derivative (BPBD) blended with polystyrene as the second layer are sandwiched between two planar mirrors. Enhancement of the luminescence and spectrally narrow emission are observed. By means of time resolved luminescence spectroscopy we show that the spontaneous emission rate is increased in the cavity.
Name Identification of People in News Video by Face Matching (2007)

Recently, there is a strong demand for making use of large amounts of video data efficiently and effectively. When considering broadcast news video, people who appear in it is one of the major interests to a viewer. This is the common motivation of recent works that focus on extracting names of people that appear in news video footages. However, these works suffer a serious problem; a person is often referred to by various names depending on situations and along time. In this paper, we propose and evaluate a method that handles this problem by identifying faces together with names. Faces are extracted by face detection technology and annotated with person name candidates extracted from closedcaption text. Then, all face-name pairs are compared by face identification technology and text matching of names. As a result, different names of a same person are identified.
How painful is juvenile chronic arthritis? (1997)

These include: References http://adc.bmjjournals.com/cgi/content/full/77/5/451#BIBL This article cites 32 articles, 9 of which can be accessed free at: Rapid responses http://adc.bmjjournals.com/cgi/eletter-submit/77/5/451 You can respond to this article at: service Email alerting top right corner of the article Receive free email alerts when new articles cite this article sign up in the box at the
Isolation and in Vitro Translation of RNAs from Developing Peach Fruit (1989)

Abstract Peach [ Prunus persica (L.) Batsch] RNA was extracted from fruit at six times during development, from leaves and from isolated ovules. These RNAs were translated in a wheat germ extract and the resulting polypeptides were compared by one-dimensional NaDodSO 4 /PoIyacrylamide gel electrophoresis (PAGE). RNAs encoding polypeptides of 100,85, 59,54,42, 41, and 25.5 kDa increased, while those encoding polypeptides of 46, 40, 25.5, and 25 kDa decreased during peach fruit development. These RNAs are present in fruit but not in ovules or leaves. This study suggests that fruit development in peach is at least partially regulated at the transcriptional level or at the level of mRNA stability.
The implications of propensity score variable selection strategies in pharmacoepidemiology: an empirical illustration (2020)

To examine the effect of variable selection strategies on the performance of propensity score (PS) methods in a study of statin initiation, mortality and hip fracture assuming a true mortality reduction of <15% and no effect on hip fracture.
Xylocoris galactinus (Fieber) (Hemiptera: Anthocoridae) newly discovered in Montana stored grain. (1994)

(Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
ChemInform Abstract: The Interleukin‐4‐Receptor: From Recognition Mechanism of Pharmacological Target Structure (2000)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Crystal-induced neutrophil activation. IX. Syk-dependent activation of class Ia phosphatidylinositol 3-kinase (2007)

The deposition of monosodium urate (MSU) crystals in the joints of humans leads to an extremely acute, inflammatory reaction, commonly known as gout, characterized by a massive infiltration of neutrophils. Direct interactions of MSU crystals with human neutrophils and inflammatory mediators are crucial to the induction and perpetuation of gout attacks. The intracellular signaling events initiated by the physical interaction between MSU crystals and neutrophils depend on the activation of specific tyrosine kinases (Src and Syk, in particular). In addition, PI-3Ks may be involved. The present study investigates the involvement of the PI-3K family in the mediation of the responses of human neutrophils to MSU crystals. The results obtained indicate that the interaction of MSU crystals with human neutrophils leads to the stimulation of class Ia PI-3Ks by a mechanism that is dependent on the tyrosine kinase Syk. We also found an increase in the amount of p85 associated with the Nonidet P-40-insoluble fraction derived from MSU crystal-stimulated human neutrophils. Furthermore, MSU crystals induce the formation of a complex containing p85 and Syk, which is mediated by the Src family kinases. Finally, evidence is also obtained indicating that the activation of PI-3Ks by MSU crystals is a critical element regulating phospholipase D activation and degranulation of human neutrophils. The latter response is likely to be involved in the joint and tissue damage that occurs in gouty patients.
Structural and Microstructural Analysis of K0.5Na0.5NbO3 Ceramics Doped with Strontium (2012)

Extended abstract of a paper presented at Microscopy and Microanalysis 2012 in Phoenix, Arizona, USA, July 29 – August 2, 2012.
Randomized Controlled Trial of Adalimumab in Patients With Nonpsoriatic Peripheral Spondyloarthritis (2014)

Treatment with adalimumab ameliorated the signs and symptoms of disease and improved physical function in patients with active nonpsoriatic peripheral SpA who exhibited an inadequate response or intolerance to NSAIDs, with a safety profile consistent with that observed in patients with AS, PsA, or other immune-mediated diseases.
A phase II study of 5-fluorouracil/L-leucovorin/oxaliplatin (mFOLFOX6) in Japanese patients with metastatic or unresectable small bowel adenocarcinoma (2017)

Although the primary endpoint was not met, mFOLFOX6 showed effective and good tolerance as a first-line treatment for SBA.
Deconvolution for positive time-frequency distributions (2002)

A method is presented for generating high-resolution time-frequency distributions (TFDs) which are everywhere nonnegative and satisfy the time and frequency marginals. These TFDs are obtained by deconvolution, wherein the effects of the smoothing window are removed from a spectrogram of the signal. The method may also be used to incorporate information from multiple spectrograms of the signal, thereby improving the result.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
ChemInform Abstract: Morita—Baylis—Hillman Alkylation of Unsaturated Thioesters (2011)

Abstract in the presence of Bu 3 P in catalytic or stoichiometric amounts
Activation of Protein Kinase C in Human Uterine Smooth Muscle Induces connexin-43 Gene Transcription through an AP-1 Site in the Promoter Sequence (1996)

Myometrial connexin-43 gap junctions are scarce throughout gestation but appear in large numbers at term to facilitate contractions during labor. The mechanisms that regulate this process are incompletely characterized. This report investigates the effects of protein kinase C activation on the regulation of connexin-43 gene transcription in human uterine smooth muscle cells. In primary myometrial cells treated with phorbol ester, transient increases in c-Fos and c-Jun protein levels were observed at 2-4 h, followed by significant increases in connexin-43 protein levels at 6-8 h. Nuclear run-on transcription analysis showed an increase in connexin-43 transcription 3 h after phorbol ester treatment. AP-1 sites were identified in the sequence of the 5'-flanking promoter region of the human connexin-43 gene at 44 and 1000 base pairs upstream of transcription start. Transcription from a reporter plasmid containing the proximal human connexin-43 promoter was increased in transfected primary cultures treated with phorbol ester. Mutation of the proximal AP-1 site in the promoter abolished the phorbol ester-dependent transactivation. This work provides evidence that transcription of the human connexin-43 gene is induced through protein kinase C activation in uterine smooth muscle cells, and that the induction involves up-regulation and activation of c-Jun and c-Fos.
ChemInform Abstract: Cesium Carbonate: A Powerful Inorganic Base in Organic Synthesis (2010)

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Neural Gas for Sequences (2003)

Abstract — For unsupervised sequence processing, standard self organizing maps (SOM) can be naturally extended by recurrent connections and explicit context representations. Known models are the temporal Kohonen map (TKM), recursive SOM, SOM for structured data (SOMSD), and HSOM for sequences (HSOM-S). We discuss and compare the capabilities of exemplary approaches to store different types of sequences. A new efficient model, the Merge-SOM (MSOM), is proposed, combining ideas of TKM and SOMSD, and which is well suited for processing sequences with dynamic multimodal densities. 1
Synthesis of 9‐Allyl‐10‐hydroxycamptothecin via Suzuki Reaction (2013)

A facile and eco‐friendly approach for synthesizing 9‐allyl‐10‐hydroxycamptothecin ( 2 ), a key intermediate for the preparation of camptothecin analogs, is described. The product was obtained in good yield and high purity (≥99% HPLC) under mild Suzuki reaction condition.
Combinatorial Surface-Enhanced Raman Spectroscopy and Spectroscopic Ellipsometry of Silver Island Films (2009)

Utilizing a combinatorial method, we used spectroscopic ellipsometry to determine the dielectric functions of silver island films over a large range of sizes and morphologies from the percolation threshold down to average particle size smaller than 5 nm. We measured films on silicon substrates with 2 and 20 nm oxide layers and compared the surface-enhanced Raman scattering properties of the films. As expected, the films on 20-nm-thick oxide substrates showed increased Raman counts due to reduced damping of the plasmon resonance; however, the optical absorption was greater in the films on 2 nm oxide. The maximum Raman scattering was observed for average particle diameters of 13.6 and 25 nm and interparticle spacings of 3.3 and 4.1 nm for the 2 and 20 nm oxide substrates, respectively. The use of a combinatorial method resulted in significantly reduced uncertainties by avoiding multiple sample preparations and allowed unambiguous identification of optimal film parameters for the different substrates.
Compressed sensing in photonics: tutorial (2022)

Traditional optical imaging and sensing methods capture signals of interest by direct sampling in the domain of interest such as by forming images on pixelated camera sensors or by regular temporal sampling of a waveform. These methods are indispensable in our daily lives and for many scientific disciplines such as microscopy in biology and spectroscopy in chemistry. Using these approaches, the sampling constraints and their impact on the bounds on signal fidelity are well understood through the Nyquist–Shannon sampling theorem. However, the problems of modern science require ever increasing amounts of data at unprecedented temporal and spatial scales and resolutions, which challenges the limits of traditional sensing. The increased availability of computational power combined with recent strides in signal processing promise to surpass many of the problems associated with traditional sensing methods through computational imaging and sensing methods. Within the realm of computational sensing, compressed sensing (CS), in particular, has enabled the capture of signals with lower sampling resources than traditionally required by the Nyquist–Shannon sampling theorem using prior information such as sparsity. In this tutorial, we focus on the operation and impact of such sub-Nyquist sampling schemes through the use of CS in photonic sensing and imaging systems. Emphasis is placed on intuition, but mathematical results are derived or cited where appropriate. Finally, we highlight several applications in macroscopic and microscopic imaging, spectroscopy, and microwave photonic sensing.
Spectrotemporal dynamics of a two-coupled-mode laser (1998)

In their review about intracavity laser spectroscopy, P. E. Toschek and V. Baev [in Laser Spectroscopy and New Ideas, edited by W. M. Yen and M. D. Levenson, Springer Series in Optical Science (Springer, Berlin, 1987)] have shown that multimode lasers are needed to obtain a high sensitivity. In this paper we show that two modes is enough. We discuss first the ideal case where only the spontaneous emission limits the sensitivity. In a second part we take into account the spatial hole burning, which couples the two modes and has for effect a lower limitation of the sensitivity. Analytical expressions are given for the modified absorption coefficient and the time evolution of the intensity of the two modes is calculated by numerical integration.
Upgrade of the 30-m x-ray pencil beam line at the Institute of Space and Astronautical Science (2015)

The 30-m x-ray pencil beam line at the Institute of Space and Astronautical Science has been upgraded. The vacuum chamber has been replaced by a new cylindrical chamber of diameter 1.8 m and length 11.3 m. Stages on which a telescope and detectors had been mounted were also replaced. At the same time, a new charge-coupled device consisting of 1240×1152 pixels of size 22.5×22.5 μm2 was introduced. The detector stage can be moved along the x-ray beam in the vacuum chamber, which enables us to vary the distance between the sample and the detectors from 0.7 to 9 m. The two stages can be moved in a square region 500×500 mm2 in the plane normal to the x-ray beam. The pitching of moving axes of Y direction (horizontal and normal to the beam) of the sample and the detector stages is somewhat large, but does not exceed 60 arc sec. The pitching of the other axes and the yawing of all the axes are less than 30 arc sec. As for rolling, we could obtain only the upper limits because of the difficulty in measuring them. The upper limit of the Z direction (vertical and normal to the beam) of the detector stage moving axis is somewhat large and is about 60 arc sec, and those of the other axes are less than 30 arc sec. A summary of the beam line performance is presented. Soon after the upgrade, the ASTRO-H Soft X-ray telescopes were calibrated in this beam line.
40 W Integrated Car Radio Audio Amplifier (2005)

This paper describes a BTL (Bridge Tied bad) class-H, high -power, high-efficiency audio amplifier for car radio applications. With a supply of 14.4 V, the output power is 40 W into an 8 /spl Omega/ load this is not possible using a normal class-B amplifier. Assuming that the music signal at the input has a normal (Gaussian) amplitude disrnbution, the dissipation is about 50% less than that of a class-B BTL amplifier with the same output power.
Preparation of diamond-shaped channels in SU-8 for optical control of the filling state (2009)

To improve control during the filling of the channels of a microfluidic device with the fluid under investigation, a new concept is presented: channels with a diamond-shaped cross section. These channels easily allow one to distinguish an unfilled channel from a filled channel by simple optical microscopy. The idea is based on the fact that incident light is totally reflected with unfilled channels, whereas it is mostly transmitted with filled channels. Preparation of such channels in thin SU-8 layers on a glass was performed via a double replication of a Si template with undercut trenches. Functionality tests with filling materials spanning the range of refractive indices of typical organic media provided an excellent contrast between filled and unfilled channels, thus demonstrating the capacity of this concept.
Simvastatin and ROCK inhibition in Th0 and Th17 systems (2012)

The deregulation of the Def6-ROCK2-IRF4 axis in murine models results in both lupus-like and rheumatoid arthritis-like disease characterized by increased IL-17 and IL-21 production that is ameliorated by ROCK inhibition. A known beneficial pleiotropic effect of statins is inhibition of ROCK activation via their effect on RhoA activation. Statins have also been reported to decrease IL-17 and IL-21 production in T cells. Whether statins exert their inhibitory effects by interfering with the ROCK2-IRF-4 interaction in CD4+ T cells is unknown. The aim of the present study is to investigate whether statins can inhibit the ROCK pathway in CD4+ T cells and inhibit IL-17 and IL-21 production.
Efficient polarization of high-angular-momentum systems (2016)

We propose methods of optical pumping that are applicable to open, high-angular-momentum transitions in atoms and molecules, for which conventional optical pumping would lead to significant population loss. Instead of applying circularly polarized cw light, as in conventional optical pumping, we propose to use techniques for coherent population transfer (e.g., adiabatic fast passage) to arrange the atoms so as to increase the entropy removed from the system with each spontaneous decay from the upper state. This minimizes the number of spontaneous-emission events required to produce a stretched state, thus reducing the population loss due to decay to other states. To produce a stretched state in a manifold with angular momentum $J$, conventional optical pumping requires about $2J$ spontaneous decays per atom; one of our proposed methods reduces this to about ${log}_{2}2J$, while another of the methods reduces it to about one spontaneous decay, independent of $J$.
On distinguishability of states of automata (2003)

We investigate variants of the notion of distinguishability of automata. The distinguishability in the sense of a given metric on the set of output symbols, the k -distinguishability and the ∞-distinguishability are considered. For each variant the exact value of the corresponding Shannon function is obtained.We find the minimum value of the parameter k for which the k -distinguishability implies the ∞-distinguishability.
Pickering Miniemulsion Polymerization Using Laponite Clay as a Stabilizer (2007)

Solid-stabilized, or Pickering, miniemulsion polymerizations using Laponite clay discs as stabilizer are investigated. Free radical polymerizations are carried out using a variety of hydrophobic monomers (i.e., styrene, lauryl (meth)acrylate, butyl (meth)acrylate, octyl acrylate, and 2-ethyl hexyl acrylate). Armored latexes, of which the surfaces of the particles are covered with clay discs, are obtained, as confirmed by scanning electron microscopy (FE-SEM) and atomic force microscopy (AFM). Overall polymerization kinetics of the Pickering miniemulsion polymerizations of styrene were investigated via gravimetry. Comparison with the bulk polymerization analogue clearly shows compartmentalization. Moreover, retardation effects up to intermediate monomer conversions are observed; they are more prominent for the smaller particles and are ascribed to the Laponite clay. A model is presented that allows for the prediction of the average particle size of the latexes produced as a function of the amounts of monomer and Pickering stabilizers used. It shows that under specific generic conditions the number of clay discs used correlates in a linear fashion with the total surface area of the latex particles. This is a direct result of the reversibility of the Laponite clay disc adhesion process under the emulsification conditions (i.e., sonication) used.
Analysis of a phase mismatched three-waveguide coupler with an optical amplifier (1987)

The optical coupler consists of three parallel dielectric waveguides. The propagation constants of each waveguide are slightly mismatched so that coupling among them is weak. Two adjacent waveguides are passive ridge guides, and the third is an active waveguide.
The Challenge of Analyzing the Proteome in Humans with Autoimmune Diseases (2005)

Analysis of blood samples from patients suffering from autoimmune diseases remains a mainstay in the clinic for initial diagnosis, prognostication, and clinical decision making. In particular, testing for the presence of serum autoantibodies has proved to be one of the most useful confirmatory assays for many different diseases. Recent genomic and transcript profiling studies have implicated certain cytokines, surface receptors, signaling pathways, and cell types in the pathogenesis of inflammatory diseases. The next obvious step is to delve into the much more complex level that follows the genome and transcriptome-the expressed proteome. This review focuses on several proteomics technologies being applied and/or developed by our laboratory for the study of autoimmunity, cancer, and cardiovascular disease, all of which are known to be associated with defects in immunity and inflammation. The findings of other participants in the recent Human Immunology Conference hosted by the Dana Foundation and the New York Academy of Sciences (May 17 & 18, 2005) are included. In particular, major pitfalls in the study of the human proteome are pointed out, and important areas for immediate investigation to move the field forward as rapidly as possible are proposed.
Maternal serum free β‐human chorionic gonadotrophin levels in twin pregnancies: Implications for screening for down's syndrome (1994)

Free beta-human chorionic gonadotrophin values are, on average, 1.90 times greater in twin pregnancies than in singleton pregnancies [95 per cent confidence interval (CI) 1.69-2.13]. This information can be used in screening for Down's syndrome, so that twin pregnancies can be interpreted in addition to singleton pregnancies.
Design and characterization of a sensitive optical micro-machined ultrasound transducer (2015)

Novel 3D intravascular or transesophageal ultrasound approaches require transducer arrays containing many small elements. Conventional piezo-electric techniques face fabrication challenges due to narrow kerfs and dense wiring. Micro-machined alternatives like CMUTs and PMUTs lack either sensitivity or bandwidth to fully compete. Therefore we developed an opto-mechanical ultrasound sensor. The absence of wiring makes it MRI compatible. The developed OMUT contains integrated photonics, which is fabricated using standard silicon-on-insulator technology, providing a small footprint and enabling mass production and ease of integration. The sensor consists of a straight waveguide and a micro-ring resonator integrated on a 124 μm wide, 2.7 μm thick acoustical membrane. Light, passing the waveguide, is partly coupled into the ring resonator. A dip appears in the spectrum of the transmitted light at the resonance wavelength of the micro-ring. If the acoustical membrane and hence the micro-ring is deformed due to an incident ultrasound wave, this is observed as a shift in the resonance wavelength of the ring. This paper presents the construction and characterization of our device. Measurement results of the linearity, frequency response, sensitivity and temperature dependence are compared with a model. The results demonstrate that our OMUT is a promising basis for future ultrasound arrays.