gebhart/patrepeval huggingface dataset:
Permeability Predictions from Acoustic Core Measurements (2014)

Core measurements published by Weger et al. (2009) are used as a training dataset. We have used a modified version of the rock physics model for carbonates of Sun (2000, 2004), to estimate permeability solely as a function of P-wave velocity and porosity in brine saturated carbonates. The results were tested against an independent database with 101 carbonate core measurements from seven different locations. The test results are promising, indicating that over 72 % of the permeabilities can be predicted within one order of magnitude. An analysis of the prediction errors indicated the validity areas of the model. The model struggles to reproduce permeability in high porous - low permeability rocks, which from thin sections were found to be oomoldic. Also low porosity - high permeability carbonates were difficult to predict. It is shown that integration of the developed model with geological knowledge will improve the prediction accuracy. This methodology elucidates the intricate link between carbonate rock frame stiffness and pore structure flow properties. It offers the potential to improve permeability predictions from wireline sonic data.
T Cell Homeostasis and Autoreactivity in Rheumatoid Arthritis (2000)

Rheumatoid arthritis (RA) is a chronic inﬂammatory disease that prima-rily aVects the synovial membrane and causes irreversible joint damage. Theprevailing pathogenetic model of RA assumes an autoimmune mechanism.Considerable evidence exists that the disease is mediated or at least regulatedby abnormal T cell responses. The most important and, so far, the onlyuniversallyimplicateddiseaseriskgenesareallelicpolymorphismsoftheHLA-DRB1 genes that serve as ligands for the T cell receptor (TCR) of CD4 T cells[1–3]. CD4 T cells are a major component of the inﬂammatory inﬁltrate inthe rheumatoid synovium. In many patients, CD4 T cells and B cells inthe synovial inﬁltrates are organized into lymphoid structures that resemblegerminal centers [4, 5]. Clonally expanded T cell populations are easily detect-able within synovial lesions and identical TCR sequences have been identiﬁedin distinct joints of the same patient, strongly suggesting that CD4 T cellsrecognize antigens in the synovium [6, 7].In spite of this unequivocal evidence of antigen-driven T cell responses, itappearsincreasinglyunlikelythatRAisanantigen-speciﬁcautoimmunedisease.In the strictest sense, autoimmunity is deﬁned as the loss of tolerance and thegeneration of an adaptive immune response to an autoantigen. Such a singleautoantigen has not been identiﬁed in RA. In contrast, recent data suggest thatrecognitionofamultitudeofself-antigensmaybeinvolvedinthediseaseprocess.RA patients have global abnormalities in the peripheral T cell repertoire thatare associated with increased T cell turnover and a contraction of repertoirediversity.Theseaberrationsmaynotonlyreﬂecttherecognitionofmultipleself-antigens but by themselves are likely to have a negative impact on peripheral
"Pale Ale" as a Nickname for Englishmen (1906)

"Pale Ale" as a Nickname for Englishmen Get access Henry Taylor Henry Taylor Search for other works by this author on: Oxford Academic Google Scholar Notes and Queries, Volume s10-V, Issue 128, 9 June 1906, Page 447, https://doi.org/10.1093/nq/s10-V.128.447d Published: 09 June 1906
The Enzymatic Deficiency in Tyrosinemia (1967)

SOME time ago I reviewed the literature on tyrosinosis to write a chapter on this subject.<sup>1</sup>This required careful restudy of the classic investigations by Dr. Grace Medes in 1927 of a metabolic disorder of tyrosine metabolism, which she named, tyrosinosis.<sup>2,3</sup>In the intervening 30 years since her studies, considerable advances have been made in our understanding of tyrosine metabolism both in vitro and in vivo. With this additional information, the biochemical findings and conclusions were reexamined. It seemed more probable that the enzymatic deficiency underlying the metabolic disorder in her patient was a deficiency of liver tyrosine transaminase (tyrosine-α-ketoglutarate-aminotransferase) rather than a deficiency of<i>p</i>-hydroxyphenylpyruvic acid (pHPPA) oxidase, as had been originally proposed. Two biochemical abnormalities were found which are more compatible with the alternative proposal: the patient excreted 3,4-dihydroxyphenylalanine (dopa) when large amounts of tyrosine were ingested; and he excreted large amounts of pHPPA but
Fabrication and molecular dynamics analyses of highly thermal conductive reduced graphene oxide films at ultra-high temperatures (2017)

Thin films with high thermal conductivity are urgently needed as heat dissipation materials for electronic devices. In this study, we developed a readily scalable roller coating method followed by ultra-high temperature annealing to prepare large-sized, free-standing, and flexible reduced graphene oxide (rGO) films with high thermal conductivity. The in-plane thermal conductivity measured by a laser flash method for the sample annealed at 2800 °C was 826.0 W m<sup>-1</sup> K<sup>-1</sup>, which was much higher than that of copper foil. X-ray diffraction, Raman, and SEM analyses indicated that, different from common chemical reduction, heat treatment at high temperature could not only remove O, H, and other impure elements but also develop the in-plane crystal size of graphene and decrease the interlayer spacing of graphene sheets. Meanwhile, tight embedding during annealing and concomitant mechanical impaction was indispensable for retaining the shape and raising the density of the films. Furthermore, molecular dynamics analyses demonstrated that point defects, pentagonal/heptagonal defects, or even large in-plane holes in graphene could be rehabilitated to a great extent during ultra-high temperature annealing. In addition, real-time temperature monitoring demonstrated that the rGO films could act as an excellent thermal dissipation material in LED packages by reducing 10%-15% of the temperature increase.
Observation of the Spectrum of Light Scattered from a Pure Fluid Near its Critical Point (1965)

Received 20 September 1965DOI:https://doi.org/10.1103/PhysRevLett.15.649©1965 American Physical Society
Passive radiofrequency shimming in the thighs at 3 Tesla using high permittivity materials and body coil receive uniformity correction (2015)

Combining high permittivity dielectric pads with an appropriate body coil receive sensitivity filter improves the image uniformity substantially compared with the situation without pads. Magn Reson Med 76:1951-1956, 2016. © 2015 International Society for Magnetic Resonance in Medicine.
Adresse des habitants de la ville d'Aurillac, présenté par M. Hébrard, contre la minorité qui affiche désobéissance et révolte contre l'autorité légitime, lors de la séance du 2 août 1791 (1888)

Andrieu César Pierre, Hébrard de Fau Pierre. Adresse des habitants de la ville d'Aurillac, présenté par M. Hébrard, contre la minorité qui affiche désobéissance et révolte contre l'autorité légitime, lors de la séance du 2 août 1791. In: Tome XXIX - Du 29 juillet au 27 août 1791. pp. 107-108.
Calibrating Differential Reflectivity on the WSR-88D (2006)

Abstract A calibration procedure of differential reflectivity on the Weather Surveillance Radar-1988 Doppler (WSR-88D) is described. It has been tested on NOAA's modified WSR-88D research and development polarimetric radar and is directly applicable to radars that simultaneously transmit and receive waves having horizontal and vertical polarization.
Suppressors of Oxygen Metabolites Fail to Reduce Vein Graft Intimal Hyperplasia (1995)

Arterial reconstruction often involves interposition of vein segments into the arterial circulation. These veins are subject to ischemia and reperfusion, with the potential for generation of reactive oxygen metabolites and subsequent vein graft injury, resulting in intimal hyperplasia. We hypothesized that perioperative pharmacologic intervention either to scavenge or to reduce the production of reactive oxygen metabolites would attenuate the initial vein graft injury and thus limit the subsequent development of intimal hyperplasia. These data create doubt as to the influence of reactive oxygen metabolites in the initiation of intimal hyperplasia in the vein graft.
GM‐CSF increases cross‐presentation and CD103 expression by mouse CD8<sup>+</sup> spleen dendritic cells (2011)

Resident CD8(+) DCs perform several functions, including cross-presenting antigen and rapidly engulfing the Gram-positive intracellular pathogen Listeria monocytogenes. Little is known about how these functions of CD8(+) DCs are modulated. Here, we show that granulocyte-macrophage CSF (GM-CSF), a cytokine that exists at low levels at steady state but is elevated during infection and inflammation, enhances cross-presentation and rapid uptake of L. monocytogenes by resident CD8(+) DCs. This previously unrecognized functional enhancement of CD8(+) DCs by GM-CSF was independent of promoting DC survival in vitro. Enhancement of these functions by GM-CSF was also marked by CD103 expression on CD8(+) DCs that was strongly regulated by GM-CSF. Our findings not only identify GM-CSF as a key molecule regulating CD8(+) DC function, but also as a factor responsible for functional heterogeneity of CD8(+) DCs that is at least substantially demarcated by CD103 expression.
Computerized 3D morphological analysis of glenoid orientation (2015)

An accurate preoperative measurement of glenoid orientation is crucial for evaluating pathologies and successful total shoulder arthroplasty. Existing methods may be labor-intensive, observer-dependent, and sensitive to the misalignment between the scapula plane and CT scanning direction. In this study, we proposed a computation framework and performed an automated analysis of the glenoid orientation based on 3D surface data. Three-dimensional models of 12 scapulae were analyzed. The glenoid cavity and external anatomical features were automatically extracted from these 3D models. Glenoid version was calculated using the scapula plane and the fulcrum axis alternatively. Glenoid inclination was measured both relative to transverse axis of the scapula and the medial pole-inferior tip axis. The mean (±SD) of the fulcrum-based glenoid version was -0.55° (±4.17°), while the scapular-plane-based glenoid version was -5.05° (±3.50°). The mean (±SD) of glenoid inclinations based on the medial pole and inferior tip was 12.75° (±5.03°) while the mean (±SD) of the glenoid inclination based on the medial pole and glenoid center was 4.63° (±4.86°). Our computational framework was able to extract the reproducible morphological measures free of inter- and intra- observer variability. For the first time in 3D, we showed that the fulcrum axis was practically perpendicular to the glenoid plane normal (radial line), and thus extended the fulcrum-based glenoid version for quantifying 3D glenoid orientation.
Mechanistic Fracture Criteria For The Failure Of Human Cortical Bone (2002)

A mechanistic understanding of fracture in human bone is critical to predicting fracture risk associated with age and disease. Despite extensive work, a mechanistic framework for describing how the underlying microstructure affects the failure mode in bone is lacking.
Induction of Long-Term Protective Immune Responses by Influenza H5N1 Virus-Like Particles (2009)

These results provide support for clinical evaluation of H5N1 VLP vaccination as a public health intervention to mitigate a possible pandemic of H5N1 influenza.
Optical amplification and stability of spiroquaterphenyl compounds and blends (2015)

In this contribution, we present a systematic investigation on a series of spiroquaterphenyl compounds optimised for solid state lasing in the near ultraviolet (UV). Amplified spontaneous emission (ASE) thresholds in the order of 1 μ/cm 2 are obtained in neat (undiluted) films and blends, with emission peaks at 390±1 nm for unsubstituted and meta-substituted quaterphenyls and 400±4 nm for para -ether substituted quaterphenyls. Mixing with a transparent matrix retains a low threshold, shifts the emission to lower wavelengths and allows a better access to modes having their intensity maximum deeper in the film. Chemical design and blending allow an independent tuning of optical and processing properties such as the glass transition.
In Situ Studies of Solid Electrolyte Interphase (SEI) Formation on Crystalline Carbon Surfaces by Neutron Reflectometry and Atomic Force Microscopy (2017)

The solid electrolyte interphase (SEI) is a complex and fragile passivation layer with crucial importance for the functionality of lithium-ion batteries. Due to its fragility and reactivity, the use of in situ techniques is preferable for the determination of the SEI's true structure and morphology during its formation. In this study, we use in situ neutron reflectometry (NR) and in situ atomic force microscopy (AFM) to investigate the SEI formation on a carbon surface. It was found that a lithium-rich adsorption layer is already present at the open circuit voltage on the carbon sample surface and that the first decomposition products start to deposit close to this potential. During the negative potential sweep, the growth of the SEI can be observed in detail by AFM and NR. This allows precise monitoring of the morphology evolution and the resulting heterogeneities of individual SEI features. NR measurements show a maximum SEI thickness of 192 Å at the lower cutoff potential (0.02 V vs Li/Li<sup>+</sup>), which slightly decreases during the positive potential scan. The scattering length density (SLD) obtained by NR provides additional information on the SEI's chemical nature and structural evolution.
Luciferase-Based Measurement of Water Contaminants (2003)

Aquatic environments are continually being subjected to a wide variety of contaminants from industrtal, agricultural, and municipal sources. These contaminants include bacterial and parasitic pathogens, as well as toxic organic and inorgamc chemical compounds.
Radiation Dose Estimation for Prospective and Retrospective ECG-Gated Cardiac CT Angiography in Infants and Small Children Using a 320-MDCT Volume Scanner (2012)

EDs for 320-MDCT volumetrically acquired ECG-gated pediatric cardiac CTA are lower than those published for conventional 16- and 64-MDCT scanners.
ChemInform Abstract: 1,3‐Dipolar Cycloaddition Reactions of Substituted Imidazolin‐1‐oxides (Nitrones) with Olefins. (1985)

Abstract Die Titelreaktion zwischen (Ia) und (II) liefert die Bicyclen (IIIa)‐(IIIc) [(IIId) bzw. (IIIe) werden analog erhalten]; die Cycloaddition verläuft regio‐ und stereospezifisch.
2D complexity reduced model for nonlinearity and I/Q imperfections in concurrent dual-band RF transmitters (2015)

Impairments in the in-phase/quadrature (I/Q) modulators can adversely affect the performance of wireless transmitters. This problem is much more noticeable in dual-band transmitters including two I/Q modulators. In this paper, a 2D Hammerstein model is proposed to model the I/Q modulator impairments and power amplifier (PA) nonlinearity in concurrent dual-band transmitters. The obtained results revealed the accuracy and the superiority of the proposed model compared to conventional 2D models.
Structural stability of disulfide mutants of basic pancreatic trypsin inhibitor: A molecular dynamics study (1996)

The structure and folding of basic pancreatic trypsin inhibitor (BPTI) has been studied extensively by experimental means. We report a computer simulation study of the structural stability of various disulfide mutants of BPTI, involving eight 250-psec molecular dynamics simulations of the proteins in water, with and without a phosphate counterion. The presence of the latter alters the relative stability of the single disulfide species [5–55] and [30–51]. This conclusion can explain results of mutational studies and the conservation of residues in homologues of BPTI, and suggests a possible role of ions in stabilizing one intermediate over another in unfolding or folding processes. © 1996 Wiley-Liss, Inc.
PROLONGED SYSTEMIC AND REGIONAL HAEMODYNAMIC EFFECTS OF INTRACEREBROVENTRICULAR ANGIOTENSIN II IN CONSCIOUS SHEEP (1996)

1. The haemodynamic mechanisms by which infusion of angiotensin II (AngII), either into the lateral cerebral ventricles (i.c.v.) or intravenously (i.v.), increased arterial pressure were studied in conscious sheep. 2. Sheep were previously fitted with flow probes for measurement of cardiac output and coronary, mesenteric, renal and iliac blood flows. 3. Intracerebroventricular AngII (10 nmol/h for 1 h) increased arterial pressure by 11 +/- 4 mmHg (P < 0.001) due to vasoconstriction, predominantly in the mesentric vasculature. These effects developed over 30 min and took 2 h to return to control. Following the infusion renal conductance increased continuously for 3 h, resulting in a parallel increase in renal blood flow (to 75 +/- 18 mL/min above control, P < 0.001). 4. Intracerebroventricular AngII increased plasma vasopressin from 0.8 +/- 0.3 to 7.2 +/- 1.8 pg/mL (P, 0.01), and reduced plasma renin concentration from 0.9 +/- 0.3 to < 0.4 nmol/L/h. 5. The pressor effect of i.v. AngII (5, 10, 25, 50 nmol/h) also depended on peripheral vasoconstriction, but the pattern of responses was different. The greatest degree of vasoconstriction occurred in the renal, followed by the mesentric and iliac vascular beds; these effects were rapid in onset and offset. 6. In conclusion, the pressor responses to both i.c.v. and i.v. angiotensin depended on peripheral vasoconstriction, but there were contrasting regional haemodynamic changes. ICV AngII caused a prolonged pressor response, mainly due to mesentric vasoconstriction possibly partly due to vasopressin release, and following the infusion there was a pronounced, long-lasting renal vasodilatation. In contrast, i.v. AngII caused vasoconstriction preferentially in the renal vascular bed and its effects were short lasting.
Effects of Estrogen and Goitrogen on Numbers and Activities of Rumen Micro-organisms (1964)

The authors wanted to study on the mechanism of the effects of estrogen or/and goitrogen in cattle fattening from the points of digestion physiology.The effects of these two hormonal substances on numbers and activities of rumen micro-organisms were examined in vivo and in vitro. Diethyl-stilbestrol (DES) was used as an estrogen and methylthiouracil (MTU) as a goitrogen.The effects of DES or/and MTU on the numbers of rumen micro-organisms in sheep were examined twice in vivo with different basal rations but no significant effect was found. The effects of these two hormonal substances on ratios of kinds of rumen protozoa in sheep were examined but no significant result was found either. It was found that when the concentrates and alfalfa pellet were given to the sheep, the number of rumen protozoa increased, and the ratio of Entodinium also increased but the one of Diplodinium decreased, comparing with sheep when the concentrates and hay were given.Using artificial rumen, the effects of DES or/and MTU on performance of cellulose digestion of rumen bacteria in cattle were examined in vitro. But no significant effect was found when the concentration of the hormonal substances was the same with the one which had been used ordinarily for cattle fattening. When the concentration of DES in tube of artificial rumen was over 5mcg/ml, the performance of cellulose digestion of rumen bacteria decreased.Using the artificial rumen, the effects of DES or/and MTU on performance of volatile fatty acids production of rumen protozoa in cattle were examined in vitro but no significant effect was found.From the results mentioned above, the authors guessed that the principal mechanism of the actions of hormonal substances in cattle fattening was not in the part of digestion physiology but in the other part, for example, the part of endocrinology.
Long-lived mantle-plume influence on an Archean protocontinent: Geochemical evidence from the 3 Ga Lumby Lake greenstone belt, Ontario, Canada (1998)

Research Article| August 01, 1998 Long-lived mantle-plume influence on an Archean protocontinent: Geochemical evidence from the 3 Ga Lumby Lake greenstone belt, Ontario, Canada Derek Wyman; Derek Wyman 1Centre for Strategic Mineral Deposits, Department of Geology, University of Western Australia, Nedlands 6009, Australia Search for other works by this author on: GSW Google Scholar Pete Hollings Pete Hollings 2Department of Geological Sciences, University of Saskatchewan, Saskatoon, Saskatchewan S7N 5E2, Canada Search for other works by this author on: GSW Google Scholar Author and Article Information Derek Wyman 1Centre for Strategic Mineral Deposits, Department of Geology, University of Western Australia, Nedlands 6009, Australia Pete Hollings 2Department of Geological Sciences, University of Saskatchewan, Saskatoon, Saskatchewan S7N 5E2, Canada Publisher: Geological Society of America First Online: 02 Jun 2017 Online ISSN: 1943-2682 Print ISSN: 0091-7613 Geological Society of America Geology (1998) 26 (8): 719–722. https://doi.org/10.1130/0091-7613(1998)026<0719:LLMPIO>2.3.CO;2 Article history First Online: 02 Jun 2017 Cite View This Citation Add to Citation Manager Share Icon Share Facebook Twitter LinkedIn MailTo Tools Icon Tools Get Permissions Search Site Citation Derek Wyman, Pete Hollings; Long-lived mantle-plume influence on an Archean protocontinent: Geochemical evidence from the 3 Ga Lumby Lake greenstone belt, Ontario, Canada. Geology 1998;; 26 (8): 719–722. doi: https://doi.org/10.1130/0091-7613(1998)026<0719:LLMPIO>2.3.CO;2 Download citation file: Ris (Zotero) Refmanager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentBy SocietyGeology Search Advanced Search Abstract The 3.0 to 2.9 Ga Lumby Lake belt of the Superior province is composed of plume-related komatiite-tholeiite sequences and calc-alkalic volcanic units, and tonalite-trondhjemite-granodiorite units formed by coeval magmatism; they are all intercalated throughout a 100 m.y. interval. These observations are inconsistent with plateau-accretion models of crustal growth. Sporadic subduction of plume-modified ocean spreading centers, followed by plume impingement beneath a northern Superior province cratonic nucleus, more readily accounts for the long duration of coexisting plume- and arc-type volcanism. The recognition of such complex geodynamic settings in the Archean has important consequences for crustal-growth models. This content is PDF only. Please click on the PDF icon to access. First Page Preview Close Modal You do not have access to this content, please speak to your institutional administrator if you feel you should have access.
Tourette Syndrome: Prediction of Phenotypic Variation in Monozygotic Twins by Caudate Nucleus D2 Receptor Binding (1996)

Tourette syndrome, a chronic tic disorder with autosomal dominant inheritance, exhibits considerable phenotypic variability even within monozygotic twin pairs. The origins of this variability remain unclear. Recent findings have implicated the caudate nucleus as a locus of pathology, and pharmacological evidence supports dopaminergic involvement. Within monozygotic twins discordant for Tourette syndrome severity, differences in D2 dopamine receptor binding in the head of the caudate nucleus predicted differences in phenotypic severity (r = 0.99); this relation was not observed in putamen. These data may link Tourette syndrome with a spectrum of neuropsychiatric disorders that involve associative striatal circuitry.