gebhart/patrepeval huggingface dataset:
The CD34 hemopoietic progenitor cell associated antigen: biology and clinical applications. (1992)

CD34, which was first detected in hemopoietic and lymphopoietic progenitors, is a heavily glycosylated Type I transmembrane protein that does not share any significant similarity with other transmembrane proteins. Its functions are still unknown. Several monoclonal antibodies were raised against CD34, and at least 4 different epitopes could be recognized. CD34 expression is confined to a few cell lines, to 1-4% of adult bone marrow mononuclear cells (including marrow-repopulating cells, all multipotent and committed myeloid progenitors, B and T lymphoid precursors, osteoclast precursors, and most likely the precursors for stromal cells), and to less than 1% of peripheral blood mononuclear cells. In non-lymphohemopoietic tissues its expression is confined to endothelial cells and to some cells of the skin. In malignancies, CD34 expression is not fully elucidated. Immature hemolymphopoietic malignancies (namely acute leukemias) and the blast cells of chronic myeloid leukemia are frequently positive. Chronic lymphoproliferative disorders and lymphomas are negative. Among other tumors, only vascular derived tumors are positive. Clinical applications of CD34+ cells include autologous transplantation of putative CD34+ stem cells isolated by positive selection from the bone marrow, and transplantation of autologous peripheral blood stem cells, using the proportion and number of CD34+ cells as a guideline for the harvesting procedure.
ESPAÇO SOCIAL DESTINADO AO EXERCÍCIO E À DIFUSÃO DA LEITURA, CULTURA E CIDADANIA (2016)

O acesso aos produtos literários na sociedade brasileira não se dá de forma igualitária. Existem vários fatores que contribuem para esse quadro, por exemplo: as desigualdades típicas de uma formação de capitalismo tardio com histórica concentração de renda e capital; a indisponibilidade de bibliotecas públicas nas periferias dos grandes centros e em cidades pequenas e médias; as diferenças de qualidade da educação básica ofertada às crianças e aos jovens das classes trabalhadoras; as disparidades culturais e simbólicas na apropriação da leitura entre as classes sociais. Nesse sentido, as políticas institucionais de construção e o fomento de bibliotecas comunitárias ganham importância decisiva na mitigação de parte desse quadro de desigualdade de acesso. Por isso, o DEMIN/UFOP, o IFMG - Ouro Preto e as comunidades dos bairros Saramenha de Cima e Morro São Sebastião, em Ouro Preto/MG, decidiram implantar e manter duas bibliotecas comunitárias para ampliar e dinamizar as oportunidades de leitura e estudo entre crianças, jovens, adultos e idosos. O foco nas bibliotecas é o desenvolvimento de atividades de estímulo à leitura, reforço escolar e ações culturais e sociais. Isso tem concorrido para melhorias na leitura e interpretação dos estudantes atendidos, na transformação do espaço de leitura em local de práticas culturais e para viabilização do acesso à produção literária brasileira e estrangeira clássica e a mais recente.
Tracing Sequence Diversity Change of RNA-Cleaving Deoxyribozymes under Increasing Selection Pressure during in Vitro Selection (2004)

In vitro selection has been used extensively over the past 10 years to create functionally diverse DNA enzymes. The majority of in vitro selection experiments to date have focused on the outcome rather than the process itself, a process that remains to be fully elucidated. In vitro selection techniques rely on the probability that some DNA molecules in a random-sequence library will fold into an appropriate tertiary structure and catalyze a desired reaction. Thus, sufficient sequence diversity in the DNA pool (and hence more catalytic DNA sequences) is a prerequisite for the successful isolation of efficient deoxyribozymes. The catalytic sequence diversity established by in vitro selection is governed largely by the choice of selection pressures, one of which is the length of the reaction time. The objective of this study was to evaluate the sequence diversity change of a pool of RNA-cleaving deoxyribozymes as a function of the reaction time. Seventeen rounds of in vitro selection were performed, and the reaction time was progressively decreased from 5 h to 5 s. A representative population from each time class was subsequently cloned and sequenced. A decline in sequence diversity was observed with decreasing reaction time, and the relationship appears to be logarithmic. In contrast, a control selection performed with a constant reaction time during each round led to a linear and comparatively very slow decrease in sequence diversity. This study provides the first methodical examination of the change in catalytic sequence diversity that occurs through the course of a deoxyribozyme selection experiment. Moreover, it represents a first step toward fully understanding the intricate pathway that lies between the beginning and end of an in vitro selection experiment.
Efficient Multi-Keyword Ranked Query on Encrypted Data in the Cloud (2012)

Cloud computing is becoming increasingly prevalent in recent years. It introduces an efficient way to achieve management flexibility and economic savings for distributed applications. To take advantage of computing and storage resources offered by cloud service providers, data owners must outsource their data onto public cloud servers which are not within their trusted domains. Therefore, the data security and privacy become a big concern. To prevent information disclosure, sensitive data has to be encrypted before uploading onto the cloud servers. This makes plain text keyword queries impossible. As the total amount of data stored in public clouds accumulates exponentially, it is very challenging to support efficient keyword based queries and rank the matching results on encrypted data. Most current works only consider single keyword queries without appropriate ranking schemes. The multi-keyword query problem was being considered only recently. MRSE [1] is one of the first research works to define and address the problem of effective yet secure ranked multi-keyword search over encrypted cloud data. However, the keyword dictionary used in MRSE is static and must be rebuilt when the number of keywords in the dictionary increases. It also has severe out-of-order problems in the matching results and does not take the keyword access frequencies into account, which greatly affects its usability. In this paper, we propose a novel approach, called MKQE, to address these issues. Only minor changes in the dictionary structure have to be done when extra keywords are introduced. We also introduce new trapdoor generation and scoring algorithms to make in-order query results. Furthermore, the keyword access frequency is considered so as to select an adequate matching file set. We conduct extensive simulations and the results prove that our approach performs much better than previous solutions.
Reactive oxygen species explicit dosimetry to predict local tumor control for Photofrin-mediated photodynamic therapy (2019)

Although photodynamic therapy (PDT) is an established modality for cancer treatment, current dosimetric quantities, such as light fluence and PDT dose, do not account for the differences in PDT oxygen consumption for different fluence rates (<i>ϕ</i>). A macroscopic model was adopted to calculate reactive oxygen species concentration ([ROS]<sub>rx</sub>) to predict Photofrin-PDT outcome in mice bearing radiation-induced fibrosarcoma (RIF) tumors. Singlet oxygen is the primary cytotoxic species for ROS, which is responsible for cell death in type II PDT, although other type I ROS is included in the parameters used in our model. Using a combination of fluences (50-250 J/cm<sup>2</sup>) and <i>ϕ</i> (50 - 150 mW/cm<sup>2</sup>), tumor regrowth rate, <i>k</i>, was determined for each condition by fitting the tumor volume vs. time to V<sub>0</sub>*exp(k*t). Treatment was delivered with a collimated laser beam of 1 cm diameter at 630 nm. Explicit dosimetry of initial tissue oxygen concentration, tissue optical properties, and Photofrin concentration was used to calculate [ROS]<sub>rx,cal</sub>. <i>ϕ</i> was determined for the treatment volume based on Monte-Carlo simulations and measured tissue optical properties. Tissue oxygenation is measured using an oxylite oxygen probe to throughout the treatment to calculate the measured [ROS]<sub>rx,mea</sub>. Cure index, CI = 1-<i>k/k</i> <sub><i>ctr</i></sub> , for tumor gowth up to 14 days were determined as an endpoint using five dose metrics: light fluence, PDT dose, and [ROS]<sub>rx,cal</sub>, and [ROS]<sub>rx,mea</sub>. PDT dose was defined as the product of the time-integral of photosensitizer concentration and <i>ϕ</i> at a 3 mm tumor depth. Preliminary studies show that [ROS]<sub>rx,mea</sub> best correlates with CI and is an effective dosimetric quantity that can predict treatment outcome.
Status of Drill-Stem Testing Techniques and Analysis (1961)

Abstract This paper is a compilation of the latest drill-stem testing techniques. New tools are described, together with present-day interpretation techniques, and their limitations are given. The importance of proper times for shut-in and flow periods are stressed. A number of suggestions for the future are given, and a rather complete list of references in the field of drill-stem testing has been supplied for use by interested readers. Introduction A drill-stem test (DST) is a temporary completion. It consists of a combination of a packer arrangement and drill pipe or tubing. Valves are present in this arrangement to open and close the tool, and pressure and temperature recording devices are employed. Upon completion of the test, the entire arrangement is withdrawn from the well. The purpose of a DST isto determine whether or not to complete the well andto obtain reservoir or aquifer information for exploration applications. The DST will render a wealth of information - e.g., a sample of the fluid itself, the actual productivity index, the reservoir pressure, the theoretical productivity index and the amount of wellbore damage. The fluid will show whether the well can be completed as an oil well, a condensate well or a gas well; or, it will show if the formation should be abandoned (for being a water producer or for being dry). Tests can be run on the sample to determine the hydrocarbons present, viscosity of the mixture, API gravity, paraffin content, pour point or gas-oil ratio. The water produced can be analyzed for salinity and electrolytes present to aid in stratigraphic correlation, and the resistivity of the water will aid the logging engineer in his evaluation of the electric logs. The DST further aids in determining gas-oil or oil-water contacts, and the proximity of pinchouts or faults.
Loopback radio frequency translator for the ACTS Mobile Terminal (2002)

The ACTS Mobile Terminal (AMT) is a ground based mobile satellite communications terminal designed to operate with the NASA Advanced Communications Technology Satellite (ACTS). With a scheduled launch in mid-1993, propagation experiments will begin in late 1993. This will be done to characterize the communications path between a fixed communication site in Cleveland, Ohio and a mobile terminal in Southern California via ACTS. The terminal uplink frequency is 29.634 GHz/spl plusmn/150 MHz and the downlink frequency is 19.914 GHz/spl plusmn/150 MHz. A pilot signal at 29.630 GHz will be transmitted from the fixed site for antenna tracking by the mobile terminal. This paper summarizes the system design and performance measurements of the Loopback Translator, a satellite simulator to be used in testing the fixed and mobile terminal hardware prior to the ACTS launch. The Translator provides full duplex, single stage up and down conversion between the 3.373 GHz Intermediate Frequency (IF) and the transmit/receive frequencies.
Estimation of Nakagami fading channel parameters with application to optimized transmitter diversity systems (2002)

An optimum power loading algorithm for transmitter diversity systems over correlated and unbalanced Nakagami (1960) paths and its performance evaluation under perfect channel estimation conditions are derived. In addition, various on-line estimators of the required Nakagami channel parameters for optimized power loading and the comparison of their mean square error via Monte Carlo simulations are presented. These estimators are used to obtain the performance of optimized transmitter diversity systems under imperfect channel estimation (ICE). These numerical results show that the diversity gain achieved by these optimized systems increases as the severity of fading decreases and as the degree of branch unbalance increases even under ICE. On the other hand, in weakly correlated and/or unbalanced branches, optimized transmitter diversity systems offer negligible gain or even losses compared to unoptimized systems because of the ICE.
The relevancy of controlled nanocrystallization on rifampicin characteristics and cytotoxicity (2016)

A novel RIF NS could be followed as an approach for enhancing RIF physicochemical characteristics with a prominence of a safer and better drug delivery.
Flowering, seeding, and seedling establishment of narrow‐leaved Snow Tussock, <i>Chionochloa Rigida</i> (1965)

Summary The infrequent flowering years of the narrow‐leaved snow tussock appear to depend on abnormally high temperatures during the long‐day period of summer in the season before flowering. Physiological induction then occurs and morphological initiation of the inflorescence may take place during autumn, or it may be delayed until early spring, i.e., for about eight months. IntenSity of flowering increases with the duration of high temperatures during the inductive period when daylength exceeds about 14 hnurs. Even so, considerable variation in the intensity of flowering occurred both between sites and between individual tussocks at a site. In their flowering response the plants appear to be insensitive to differences in light intensity. Inflorescence development resembles that already described for the genus. It is increasingly delayed at higher altitudes, but is not subject to control by daylength. Floret size and seed weight decrease significantly with altitude. Seed set and viability are usually satisfactory at sites below 1,300 m, but above 1,000 m seed set is variable and usually small, and moreover, viability is low. Some germination and establishment occur at most sites studied, but viable seeds may remain dormant on the ground for several years. However, fire may lead to immediate germination and establishment of many seedlings. Because of the longevity of individual tussocks the number of seedlings needed to maintain the status quo is relatively small. There is little indication that narrow‐leaved snow tussock is a relic species in the areas studied.
Signal-to-noise ratio degradation with channel mismatch (in magnetic recording) (1991)

Sensitivities of different run-length-limited coding and equalization/detection schemes to channel response variations have been investigated. Channel variations considered are due to the head-medium velocity variations and head-medium spacing fluctuations, reflected in the height and width changes in the read pulse. Given equalizers/detectors are first tuned to a specific value of PW50, the half-height width of the read pulse. The signal-to-noise ratio degradation was observed as the actual PW50 is varied around this nominal value. The results show that the sensitivity varies widely across different detectors. For example, the partial response maximum likelihood (PRML) schemes, which achieve large performance advantages over peak detection under ideal conditions, are highly sensitive to channel variations and perform worse than peak detection as the PW50 mismatch becomes large. On the other hand, the recently introduced fixed-delay tree search with decision feedback (FDTS/DF) exhibits good resistance to channel variations while achieving favorable nominal performance.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Overview on In-Space Internet Node Testbed (ISINT) (2000)

The Satellite Networks and Architecture Branch has developed the In-Space Internet Node Technology testbed (ISINT) for investigating the use of commercial Internet products for NASA missions. The testbed connects two closed subnets over a tabletop Ka-band transponder by using commercial routers and modems. Since many NASA assets are in low Earth orbits (LEO's), the testbed simulates the varying signal strength, changing propagation delay, and varying connection times that are normally experienced when communicating to the Earth via a geosynchronous orbiting (GEO) communications satellite. Research results from using this testbed will be used to determine which Internet technologies are appropriate for NASA's future communication needs.
Synthesis and characterization of oxime resin of poly(4‐viny1, 2′‐carboxybenzophenone) and its metal polychelates (1995)

Abstract The synthesis and characterization of oxime resin of poly(4‐vinyl, 2′‐carboxybenzophenone) is described and its exchange properties for Cu(II), Ni(II), and Co(II) are studied. The metal poiycheiates are investigated by magnetic measurements, diffuse reflectance spectroscopy, and infrared spectroscopy. © 1995 John Wiley & Sons, Inc.
A Middleware for the Internet of Things (2016)

The Internet of Things (IoT) connects everyday objects including a vast array of sensors, actuators, and smart devices, referred to as "things" to the Internet, in an intelligent and pervasive fashion. This connectivity gives rise to the possibility of using the tracking capabilities of things to impinge on the location privacy of users. Most of the existing management and location privacy protection solutions do not consider the low-cost and low-power requirements of things; or, they do not account for the heterogeneity, scalability, or autonomy of communications supported in the IoT. Moreover, these traditional solutions do not consider the case where a user wishes to control the granularity of the disclosed information based on the context of their use (e.g. based on the time or the current location of the user). To fill this gap, a middleware, referred to as the Internet of Things Management Platform (IoT-MP) is proposed in this paper.
Aggravation of Arrhythmia: (1993)

Aggravation of arrhythmia, defined as worsening of a preexisting arrhythmia or the occurrence of a new arrhythmia, is a common complication of antiarrhythmic drug therapy. Although it is largely an unpredictable event, patients at greatest risk are those with a history of congestive heart failure due to systolic dysfunction who present with a sustained ventricular tachyarrhythmia. As a rule, aggravation of arrhythmia is an early event, occurring within the first few days of initiating therapy. However, in the Cardiac Arrhythmia Suppression Trial (CAST), the increased sudden death mortality due to drug therapy, which was a result of arrhythmia aggravation, occurred throughout the entire duration of the trial, suggesting that arrhythmia aggravation can also be a late complication of therapy. Also disturbing was the fact that patients in CAST were low risk and did not have congestive heart failure or a serious ventricular tachyarrhythmia. This suggests that another important risk factor is myocardial ischemia and its potentially dangerous interaction with antiarrhythmic drugs. In patients with heart disease, especially those with coronary artery disease, antiarrhythmic drugs must therefore be used cautiously. Close and continuous follow-up is mandatory.
Notizen: N-Alkyl-bis-(chlorsulfonyl)-imide (1970)

am 23. Septem ber 1970
Lead Immobilization Using Phosphoric Acid in a Smelter-Contaminated Urban Soil (2001)

Transformation of soil lead (Pb) to pyromorphite, a lead phosphate, may be a cost-effective remedial strategy for immobilizing soil Pb and reducing Pb bioavailability. Soil treatment using phosphoric acid (H3PO4) was assessed for its efficacy to reduce Pb solubility and bioaccessibility. Soil containing 4,360 mg of Pb kg(-1), collected from a smelter-contaminated site in Joplin, MO, was reacted with 1,250, 2,500, 5,000, and 10,000 mg of P kg(-1) as H3PO4. The reaction was followed by measurements of Pb bioaccessibility, solubility products, and microprobe analyses. Soluble Pb concentration in the soil decreased with increasing H3PO4 addition. Adding 10,000 mg of P kg(-1) reduced bioaccessible Pb by 60%. The logarithm of bioaccessible Pb decreased as a linear function of increasing H3PO4 addition with an R2 of 0.989. A higher soil/solution ratio was required to extract bioaccessible Pb after the treatment. Microprobe analyses showed that the Pb particles contained P and Cl after the reaction, and the spectra generated by the wavelength-dispersive spectrometer were similar to those of synthetic chloropyromorphite. Lead solubility in the P-treated soil was less than predicted for hydroxypyromorphite [Pbs(PO4)3-OH] and greater than predicted for chloropyromorphite [Pbs(PO4)3Cl]. The P treatment caused approximately 23% redistribution of soil Pb from the clay and silt size fractions to the sand fraction. Soil treatment with H3PO4 resulted in the formation of a compound similar to chloropyromorphite and reduced bioaccessibility of soil Pb, which may have a potential as an in situ technique for Pb-contaminated soil remediation.
It's all in the ions (2001)

Bill Graham, who recently wrote about technological plasmas (March pp31–36), should note that these materials are, by his own definition, far more commonplace than his description of their applications might make them seem.
Compatibility of Bacillus thuringiensis and Captan When Used In a Mixture for Treating Seed Corn for Moth Control1 (1983)

Captan (Orthocide) in aqueous suspension at 58.6 mg of Al/ml prevented germination of Bacillus thuringiensis Berliner (Dipel) spores but did not kill the spores. Upon dilution with water, spores that had been incubated with captan for 4 h germinated and produced colonies on agar plates. Captan had no effect on the toxicity of B. thuringiensis to almond moths, Ephestia cautella (Walker), and only a slight negative effect on toxicity to Indianmeal moths, Plodia interpunctella (Hübner), perhaps because of its effects on the spores to which this species is susceptible. Captan alone was slightly toxic to these insect species, but it did not increase the toxicity of B. thuringiensis in mixtures.
The use of in-line repeaters in leaky feeder radio systems for coal mines (1978)

Leaky feeder techniques are being used increasingly to provide radio communication with men and vehicles in mines and tunnels. A continuing study by the UK National Coal Board has devoted considerable attention to the use of line-powered repeaters in such systems to compensate for line losses as they occur. Several different ways of achieving duplex communication with simple one-way repeaters have been developed or proposed, and these are capable of providing a far more even and reliable performance than was possible with the earlier multiple-base-station operation. The engineered systems described have been developed primarily for coal mines, where considerations of intrinsic safety impose severe restrictions on line-fed power. The resulting need for highest efficiency in the repeaters overrides considerations of linearity, and the threat of intermodulation interference arises in multichannel operation. This in turn may be countered by further system techniques such as time-division-multiplexing and diversity.
A new design for the disk-type molecular pump (1990)

This new design of the disk-type molecular pump, in which the direction of momentum transferring to gas molecules by a rotating disk is identified with the pumping direction of the pump, is described in this paper. When a pump is constructed in a series of two stages, the pumping speed and maximum compression ratio of the present pump for dry air increases by 50% and 53%, respectively, as compared with the previous type.