gebhart/patrepeval huggingface dataset:
Studies on Zinc in Poultry Nutrition (1958)

STUDIES on zinc in the nutrition of the chick by Edwards, Young and Gillis (1958) have shown that the chick can obtain small quantities of zinc from feed and water and zinc-galvanized materials. Zinc may be obtained from the latter either by direct contact or by contamination of the feed and water from these materials. This paper is a report on the study of the chicks’ requirement for zinc under carefully controlled experimental conditions where special precautions were taken to isolate the chicks from any environmental zinc. Although O’Dell and Savage (1957) and Edwards et al. (1958) have described the general symptoms of a zinc deficiency in chicks, the severe zinc deficiency symptoms encountered in this study are described in detail and illustrated. EXPERIMENTAL Single Comb White Leghorn cockerels were used in all experiments. In five experiments, the chicks were housed in plastic cages with stainless steel tops. Five chicks . . .
Cholesteryl ester transfer from phospholipid vesicles to human density lipoproteins. (1981)

The exchange of cholesteryl esters between different lipoproteins was reported to bae mediated by a protein present in human plasma. In this study wer have examined the movement of cholesteryl ester from unilamellar phospholipid vesicles to high density lipoprotein (HDL). Experimental conditions were establisehd so that vesicles containing egg yolk lecithin and cholesteryl oleatea (molar ratio of 86:1) could be incubated with human HDL so that neaither disruption of particles nor transfer of lipid occurred. Addition of human lipoprotein-deficient plasma to the system promoted the transfer of cholesteryl oleate, but not phospholipid, from vesicles to HDL. Cholesteryl oleate transfer was dependent upon amount of HDL or lipoproteain-deficient plasma added and occurred when either HDL2 or HDL3 were present. Addition of unesterified cholesterol to the vesicles did not influence lcholesteryl ester transfer to HDL. When phospholipid vesicles containing both cholesteryl oleate and triolein (molar ratio 86:1:1) were incubated with HDL and lipoprotein-deficient plasma, only cholesteryl oleate was transferred from the vesicles to HDL. Lipoprotein-deficient plasma derived from rabbits promoted the selective transfer of cholesteryl oleate from these visicles, but rat plasma did not cause any movement of cholesteryl oleate or triolein from vesicles to HDL. HDL containing labeled cholesteryl esters was prepared and incubated with vesicles containing unlabeled cholesteryl esters or phospholipid alone. Addition of lipoprotein-deficient plasma did not promote transfer of cholesteryl esters from HDL to vesicles, whereas transfer from HDL to low density lipoprotein was readily observed. The results indicated that a protein present in rabbit and human plasma is effective in the selective, unidirectional transport of cholesteryl esters from a phospholipid bilayer to a plasma lipoprotein.
Web information analysis for open-domain decision support (2011)

In this paper, we investigate the effectiveness of the system design of a Web information analysis for open-domain decision support. In order to make decisions, it is required to collect and compare information from various view points. In case of making decisions based on Web information, however, it is difficult to obtain diverse information from variety of sources by using current search engines. Based on this observation, we design a system for supporting open-domain decision making, which analyzes Web information. Among the major design decisions are to focus on two elements, i.e. identifying the source of information and the extraction of informative content, and to organize the two elements so that the user can quickly grasp who is saying what on the Web. The assumption behind such decisions is that information organized in such a way would facilitate proper judgments in the user's decision making process. We conduct users evaluation to verify the effectiveness of our approach. In the result, it is confirmed that our system is superior to current search engine for grasping organized information from different stance of senders and supports the process of decision making, by (i) uncovering biases, (ii) showing various opinions from multiple view points, (iii) revealing information sources.
Seafloor borehole geophysical observatories in the western Pacific (2010)

Seismological networks provide critical data for better understanding the dynamics of the Earth; however, a great limitation on existing networks is the uneven distribution of stations. In order to achieve a more uniform distribution of seismic stations, observatories must be constructed in the ocean basins. The best configuration for oceanic seismic observatories is thought to be placement of seismometers in deep boreholes drilled into oceanic basement rocks. We constructed four borehole geophysical observatories in the western Pacific area, where plate-consuming boundaries are concentrated, from 1999 to 2001. The four seafloor borehole observatories, which were installed in cooperation with Ocean Drilling Program, are situated at three sites. The geophysical observatories were designed to work as stand-alone systems. The system of these observatories is basically identical except for geophysical sensors and the power supply. From an analysis of the data from broadband seismometers, we confirm that seismic observation in deep-sea borehole gives the best environment for long-term, low-noise, high-resolution earthquake observation in marine areas. Two observatories were collecting the data from the tiltmeter which recorded the earth tides clearly. It is not so difficult to connect the borehole system to a seafloor cable system, because the borehole system works with low voltages of power supply. It is important to cooperate with Integrated Ocean Drilling Program (IODP) for establishment of standard technology of connecting a borehole observation system to a seafloor cable system.
Generation of 400-fs solitons with 2-MHz repetition rate by a Yb-fiber laser (2006)

We study the minimum repetition rate achievable with a Yb fiber laser. We find that a cavity with large anomalous dispersion generates 400-fs, near-transform-limited pulses at repetition rate of 2 MHz
The receptor deformation model of TCR triggering (2008)

Signal initiation from the T cell antigen receptor (TCR) by its ligand, peptide antigen presented by major histocompatibility complex (pMHC), is a critical step in immune responses. How TCR is “triggered” by ligand binding is still unclear. Using lipid bilayer and plastic based artificial antigen presenting systems, we demonstrate that TCR can be triggered by a very low number (<10) of monomeric agonist pMHCs anchored on a surface. TCR triggering was not dependent on the presence of endogenous pMHCs. It was, however, critically dependent on active T cell adhesion to the surface and intact actin cytoskeleton function. Based on these observations, and the dynamic T cell/APC interaction observed in vivo by other groups, we propose the receptor deformation model of TCR triggering. In this model, TCR signaling is initiated by conformational changes of the TCR/CD3 complex, induced by a pulling force originating from the cytoskeleton, and transmitted through pMHC‐TCR binding interactions with enough strength to resist rupture. The increased dissociation rate of pMHC‐TCR interaction under force should facilitate fast and efficient TCR serial triggering by a single agonist pMHC, thus explaining the sensitivity of TCR triggering. This model also offers “pMHC‐TCR binding strength under force” as the parameter that defines the specificity of TCR triggering, i.e., the ability and potency of certain pMHCs to trigger TCR.
SULFATE RETENTION BY SPODOSOLS IN THE PRESENCE OF ORGANIC LIGANDS (1994)

The aim of this work was to study the influence of low molecular weight organic acid concentration (0 to 1600 μmol C L−1) and type (oxalic, citric (CI), salicylic) and of solution pH (3.2 to 4.7) on the kinetics of SO4 sorption by the B horizon of two Spodosols (HER and CON) from the Lower Laurentians, Quebec. Using a miscible displacement technique, the soil materials were leached at a flow rate of 0.2 ml min−1 for 6 h at 25°C. The slope parameter (1/β) of the Elovich equation was used as an apparent SO4 sorption rate. The presence of organic ligands in solution reduced SO4 sorption by the HER B and the CON B horizons from 543 to 365 μmol SO4 kg−1 and from 1053 to 642 μmol SO4 kg−1, respectively. For both soils, 1/β values were always higher (97 to 51 μmol kg−1 In min−1 (HER) and 256 to 135 μmol kg−1 In min−1 (CON)) in systems that were free of organic acids; however, the relationships between the properties of the acids and their relative SO4 sorption inhibition capacity was not clear. The extent of SO4 sorption inhibition increased considerably as CI concentration was augmented from 100 to 1600 μmol C L−1. The efficiency of CI in reducing SO4 sorption by the HER B horizon was pH dependent, with SO4 sorption during the experiment decreasing by 23% at pH 3.2 and by 355% (desorption) at pH 4.7. The presence of CI led to the desorption of native exchangeable SO4 when the pH was above 4.2 or when the total C concentration was high (1600 μnol C L−1). The data thus reveal that temporal changes in C cycling can affect SO4 mobility in acidic forest soils with potential implications on the transport of nutrient cations if the total anionic equivalent charge of the soil solution is increased.
Carbon Dioxide Separation Using a High-toughness Ion Gel with a Tetra-armed Polymer Network (2014)

Abstract A high-performance CO2 separation membrane consisting of an ion gel has been prepared. The tetra-armed poly(ethylene glycol) ion gel contains a large fraction of ionic liquid (94 wt %) and shows excellent CO2 permselectivity over a wide temperature range, up to 100 °C. We also demonstrate that the ion gel can absorb CO2 without solvent seeping at a high pressure of 3 MPa.
Patch Residence Time and Encounters With Parasitised Hosts: a Reaction (1992)

Patch residence time of a foraging parasitoid is determined by different interplaying events. It has been shown that for some species initial motivation to search the patch is modified by ovipositions and that the effect depends on their timing. Here, I address the question whether encounters with parasitised hosts affect the probability that a parasitoid will leave a patch. I show that, like the effect of ovipositions, a possible effect of encounters with parasitised hosts would depend on the sequence of encounters with parasitised hosts and ovipositions and their timing. Therefore, experimental data collected to demonstrate a possible effect cannot be analysed with simple non-parametric statistics, but should be analysed using Cox (1972) proportional hazards model. I argue that experimental data and statistical analysis used by VAN LENTEREN (1991), do not allow the conclusion that encounters with parasitised hosts as such have a decremental effect on patch time. I also show that previous experience with ovipositions in unparasitised hosts is not needed to generate shorter patch times on patches containing parasitised hosts.
A Novel Photoreversible Photochromic System Involving a Hydrogen Transfer/Cyclization Sequence. (2003)

Abstract For Abstract see ChemInform Abstract in Full Text.
Detection of mycobacterial lipid antigens by a combination of thin-layer chromatography and immunostaining (1986)

An immunostaining method is described for the direct detection of mycobacterial lipid antigens on thin-layer chromatograms, no prior purification of the crude lipid extract is required. Analysis of Mycobacterium scrofulaceum serovar 41 gave positive reactions for the polar, but not the non-polar, glycopeptidolipids, with an antiserum against whole cells of the same strain. The family of phosphatidylinositol mannosides did not react with this antiserum but a reaction was obtained with an antiserum against intracellular material from another strain.
Competitive inhibition by verapamil of ATP-dependent high affinity vincristine binding to the plasma membrane of multidrug-resistant K562 cells without calcium ion involvement. (1989)

Verapamil, a calcium channel blocker, can inhibit the efflux of antitumor agents from multidrug-resistant cells and reverse drug resistance. We have recently reported that the plasma membrane prepared from an adriamycin (ADM)-resistant variant (K562/ADM) of human myelogenous leukemia K562 cells showed ATP/Mg2+-dependent high affinity binding of vincristine (VCR), which is closely related to the drug transport mechanism in this cell line. To clarify how calcium channel blockers inhibit the transport of antitumor agents from the resistant cells, we analyzed the effect of calcium channel blockers and Ca2+ ion on the VCR binding to K562/ADM plasma membrane. The ATP-dependent VCR binding was inhibited by calcium channel blockers (verapamil, nicardipine, and diltiazem), which are known to inhibit drug efflux from the resistant cells. Addition of [ethylenebis(oxyethylenenitrilo)]tetraacetic acid or high concentration of Ca2+ decreased the amount of VCR binding to some extent; however, a substantial amount of VCR still could bind to K562/ADM plasma membrane. The inhibitory effect of verapamil on the VCR binding was observed regardless of the Ca2+ concentration. Klotz plot analysis revealed that the inhibition of the VCR binding to K562/ADM plasma membrane by verapamil was competitive. Dissociation constant (Kd) of VCR and apparent inhibitory constant (Kiapp) of verapamil were calculated to be 0.1 +/- 0.1 microM (SD) and 1 +/- 1 microM, respectively. These results indicate that Ca2+ ion is not required for the VCR binding and that verapamil competitively inhibits the VCR binding without concerning Ca2+ ion. Antitumor agents (vinblastine, actinomycin D, ADM, and colchicine) and other agents known to reverse multidrug resistance (nicardipine, diltiazem, cyclosporin A, quinidine, and trifluoperazine) also inhibited the VCR binding competitively.
The <i>Streptococcus pneumoniae</i> Beta-Galactosidase Is a Surface Protein (2000)

The beta-galactosidase gene of Streptococcus pneumoniae, bgaA, encodes a putative 2,235-amino-acid protein with the two amino acid motifs characteristic of the glycosyl hydrolase family of proteins. In addition, an N-terminal signal sequence and a C-terminal LPXTG motif typical of surface-associated proteins of gram-positive bacteria are present. Trypsin treatment of cells resulted in solubilization of the enzyme, documenting that it is associated with the cell envelope. In order to obtain defined mutants suitable for lacZ reporter experiments, the bgaA gene was disrupted, resulting in a complete absence of endogenous beta-galactosidase activity. The results are consistent with beta-galactosidase being a surface protein that seems not to be involved in lactose metabolism but that may play a role during pathogenesis.
Can We Continue Research in Splenectomized Dogs? <i>Mycoplasma haemocanis:</i> Old Problem – New Insight (2004)

We report the appearance of a Mycoplasma haemocanis infection in laboratory dogs, which has been reported previously, yet, never before in Europe. Outbreak of the disease was triggered by a splenectomy intended to prepare the dogs for a hemorrhagic shock study. The clinical course of the dogs was dramatic including anorexia and hemolytic anemia. Treatment included allogeneic transfusion, prednisone, and oxytetracycline. Systematic follow-up (n = 12, blood smears, antibody testing and specific polymerase chain reaction) gives clear evidence that persistent eradication of M. haemocanis is unlikely. We, therefore, had to abandon the intended shock study. In the absence of effective surveillance and screening for M. haemocanis, the question arises whether it is prudent to continue shock research in splenectomized dogs.
Numerical Integration of Fluid Power Circuit Models Using Two-Stage Semi-Implicit Runge-Kutta Methods (1994)

Fluid power circuits that contain fluid volumes of different orders of magnitude are difficult to simulate because the system of ordinary differential equations is numerically stiff. Even algorithms specially designed for stiff systems require excessively small time steps to avoid numerical oscillation in simulations of some circuits. In this paper the accuracy and numerical stability of several two-stage semi-implicit Runge-Kutta methods that have been proposed in circuit simulation literature are analysed and compared. It is shown that, for integration of very stiff circuits, the best method in this class is an L-stable method. A simple numerical example is used to verify the theoretical results. The example includes a novel way of modelling orifice flow that is especially suitable for numerical simulations.
Structures of Two C<sub>13</sub>-Norisoprenoid Glucosidic Precursors of Wine Flavor (1994)

ABSTRACT The β-D-glucopyranosides of (3R,8E)-3-hydroxy-β-damascone and (6R,7E,9R)-3-oxo-α-ionol have been characterized in a Riesling wine glycosidic extract by means of GC/MS analysis of their trifluoroacetylated derivatives and synthesis of authentic racemic compounds. The absolute configurations were determined by 1H-NMR spectros-copy of the diastereomeric esters prepared from (R)-2-phenyl propionic acid and racemic (E)-3-hydroxy-β-damascone and by comparison with (6R,7E,9R)-3-oxo-α-ionol extracted from tobacco. These two glucosides were also identified in wines and grapes from other Vitis vinifera cultivars
Shift Multiplexed Holographic 3-D Disk System (1996)

We have demonstrated for the first time a fully functional holographic disk system using shift multiplexing. The architecture of our system is similar to the compact disc, but with higher storage density and data transfer rate. Figure 1 shows the experimental setup. An amplitude data mask containing 590,000 random bits (pixels) is imaged to the detector plane by a pair of Nikon F/1.4 50mm camera lenses. A 120mm glass substrate coated with a holographic recording medium (DuPont's HRF-150 100 micron thick photopolymer) is placed slightly after the Fourier plane of the camera lenses. The photopolymer disk is rotated by a microstepping motor capable of 125,000 steps per revolution. A F/1.4 CCD camera lens is used to create the spherical reference beam necessary for shift multiplexing [1]. The stored data is retrieved by a CCD camera placed at the detector plane.
Combined Electromyographic and Gas Urethral Pressure Profilometry (1976)

Combined electromyographic and gas urethral pressure profilometry provide for rapid assessment of urethral function in neurological dysfunction of the detrusor muscle and urethra.
A Convenient Synthesis of γ-Hydroxy-α-methylene Silanes (1996)

ADVERTISEMENT RETURN TO ISSUEPREVNoteNEXTA Convenient Synthesis of γ-Hydroxy-α-methylene SilanesAnthony G. M. Barrett and Peter W. H. WanView Author Information Department of Chemistry, Imperial College of Science, Technology and Medicine, South Kensington, London SW7 2AY, U.K. Cite this: J. Org. Chem. 1996, 61, 24, 8667–8670Publication Date (Web):November 29, 1996Publication History Received30 May 1996Published online29 November 1996Published inissue 1 January 1996https://doi.org/10.1021/jo9610063Copyright © 1996 American Chemical SocietyRequest reuse permissionsArticle Views161Altmetric-Citations17LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit Read OnlinePDF (216 KB) Get e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information SUBJECTS:Aldehydes,Chemical reactions,Group 14 compounds,Inorganic compounds,Reagents Get e-Alerts
Hydrolysis of heparinase I to synthetic heparin-pentasaccharide and effect on its anti-factor Xa activity (2001)

The hydrolysis of Heparinase I (from Flavobacterium heparinase, EC 4.2.2.7) to synthetic heparin-pentasaccharide (SHP) which contained an antithrombin III binding site was examined. The kinetics of this reaction was studied and the products were separated by strong anion exchange high performance liquid chromatography (SAX-HPLC). The structure of disaccharide and trisaccharide derived from SHP were confirmed by NMR and MS techniques. The experiment results showed that, heparinase I, which currently is used as a heparin reversal agent, can also reverses this synthetic pentasaccharide and make it losing its anti-factor Xa activity.
Successful Living Placement for Adults with Disabilities: (1996)

This article presents a study which was implemented to investigate successful community living in rural non-elders with chronic physical disabilities. Based on the results of an initial naturalistic study, a survey design was used to identify factors which distinguish persons with disabilities between the ages of 16-65 in institutional settings from their counterparts in community-based settings. The findings revealed significant differences in desire for autonomy, satisfaction with participation in the level of decision making around living environment, knowledge of community living and service options, fear of being alone in the community, support from family and personal care assistance in the community and socialization patterns. Yet no significant differences in functional status or need for assistance in activities of daily living was noted between the groups. The study suggests that living placement is not a function of medical or activities of daily living assistance need, but rather is a complex phenomenon comprised of numerous personal, social, resource and environmental factors.
Isolation of Hydroxyoctaprenyl-1′,4′-hydroquinone, a new Octaprenylhydroquinone from the Marine Sponge <i>Sarcotragus spinosulus</i> and Evaluation of its Pharmacological Activity on Acetylcholine and Glutamate Release in the Rat Central Nervous System (2014)

Three polyprenyl-1',4'-hydroquinone derivatives, heptaprenyl-1',4'-hydroquinone (1), octaprenyl-1',4'-hydroquinone (2), and hydroxyoctaprenyl-1',4'- hydroquinone (3) were isolated from the marine sponge Sarcotragus spinosulus collected at Baia di Porto Conte, Alghero (Italy). Our findings indicate that the compounds isolated from S. spinosulus can significantly modulate the release of glutamate and acetylcholine in the rat hippocampus and cortex and might, therefore, represent the prototype of a new class of drugs regulating glutamatergic and cholinergic transmission in the mammalian central nervous system.
Proposing a RPL based protocol for intelligent connected vehicles (2014)

According to the growth of different projects and research in the transportation field and also connected, automated and intelligent vehicles the use of effective protocols and standardization is a growing necessity in this context. In this paper we customized an existing internet standard which is called RPL (Routing Protocol for Low Power and Lossy Networks) for connected vehicles. RPL is flexible and has special specifications such as supporting many low power and lossy nodes, different traffics and self-healing. We believe customized RPL could be suitable for connected vehicles. Our proposed RPL with respect to the Quality of Service (QoS) parameters and the simulation results with different scenarios prove our claims.