gebhart/patrepeval huggingface dataset:
Effect of PCBM Concentration on Photoluminescence Properties of Composite MEH‐PPV/PCBM Nanoparticles Investigated by a Franck–Condon Analysis of Single‐Particle Emission Spectra (2009)

The emission of composite conjugated polymer (MEH-PPV)/fullerene (PCBM) nanoparticles is investigated by single particle spectroscopy (SPS), and changes in vibronic structure with nanoparticle composition are evaluated by means of a detailed Franck-Condon analysis. Consistent with previous reports we find that the emission spectra can be modeled as the superposition of two types of emitters, one with aggregate character and one with molecular character. Major findings from the fitting of the SPS data to a Franck-Condon model are that 1) the occurrence of each of the two types of emitters changes with nanoparticle composition to the point that no aggregate emitters are detected (at 50 wt% PCBM), 2) at the highest PCBM doping levels (75 wt% PCBM) aggregate emitters reappear due to nanoscale phase separation in the composite nanoparticles, 3) the molecular emitters show small Huang-Rhys factors that increase with PCBM doping, indicative of extensive delocalization and exciton migration that is reduced by the disorder introduced in the polymer material by PCBM doping and 4) the aggregate emitters show large Huang-Rhys factors, indicative of the localized nature of these energy trap sites, with a broad distribution of values of these Huang-Rhys factors. The latter observation suggests a broad heterogeneous distribution of aggregate morphologies in blended conducting polymer materials, which can be attributed to variations in polymer chain folding and stacking at the aggregate sites. The reported results obtained by the SPS approach show how blending conjugated polymers with fullerenes at various doping levels induces changes in interchain interactions and aggregate site density even at length scales below a few tens of nanometers that affect conjugated polymer material properties, an observation that has gone unnoticed in bulk studies of blended conjugated polymer films.
Immunological Characterization of <i>Escherichia coli</i> O157:H7 Intimin γ1 (2002)

Portions of the intimin genes of Escherichia coli O157:H7 strain E319 and of the enteropathogenic E. coli O127:H6 strain E2348/69 were amplified by PCR and cloned into pET-28a+ expression vectors. The entire 934 amino acids (aa) of E. coli O157:H7 intimin, the C-terminal 306 aa of E. coli O157:H7 intimin, and the C-terminal 311 aa of E. coli O127:H6 intimin were expressed as proteins fused with a six-histidine residue tag (six-His tag) in pET-28a+. Rabbit antisera raised against the six-His tag-full-length E. coli O157:H7 intimin protein fusion cross-reacted in slot and Western blots with outer membrane protein preparations from the majority of enterohemorrhagic and enteropathogenic E. coli serotypes which have the intimin gene. The E. coli strains tested included isolates from humans and animals which produce intimin types alpha (O serogroups 86, 127, and 142), beta1 (O serogroups 5, 26, 46, 69, 111, 126, and 128), gamma 1 (O serogroups 55, 145, and 157), gamma 2 (O serogroups 111 and 103), and epsilon (O serogroup 103) and a nontypeable intimin (O serogroup 80), results based on intimin type-specific PCR assays. Rabbit antisera raised against the E. coli O157:H7 C-terminal fusion protein were much more intimin type-specific than those raised against the full-length intimin fusion protein, but some cross-reaction with other intimin types was also observed for these antisera. In contrast, the monoclonal antibody Intgamma1.C11, raised against the C-terminal E. coli O157 intimin, reacted only with preparations from intimin gamma 1-producing E. coli strains such as E. coli O157:H7.
Trichloroethylene and methyl chloroform in groundwater: A problem assessment (1981)

The national effort of past decades to reduce pollution has made great strides on some fronts, while practically ignoring potential disasters on others. Billions of dollars have been expended to equip and operate air pollution control systems, such as electrostatic precipitators, SO 2 scrubbers, and catalytic converters. Similarly, water pollution control has seen tremendous investment in both the industrial and municipal sectors, including advanced waste treatment practices for phosphorus removal, nitrification and denitrification facilities, and tertiary organic removal via carbon adsorption. Groundwater pollution remains a problem of immense importance, and only recently have methods been developed to help decontaminate polluted wells.
Escape analysis for object-oriented languages (1999)

Escape analysis [27, 14, 5] is a static analysis that determines whether the lifetime of data exceeds its static scope.
Novel human lncRNA–disease association inference based on lncRNA expression profiles (2013)

The code of LRLSLDA is freely available at http://asdcd.amss.ac.cn/Software/Details/2.
ZrNbCuNiAl bulk metallic glass matrix composites containing dendritic bcc phase precipitates (2002)

We report on phase formation of a multicomponent Zr66.4Nb6.4Cu10.5Ni8.7Al8 glass-forming alloy upon copper mold casting. A bcc phase embedded in a glassy matrix forms for moldcast bulk samples yielding an in-situ bulk metallic glass matrix composite upon slow cooling from the melt. Upon annealing, the first exothermic transformation of the material is related to precipitation of an icosahedral phase from the glassy matrix. The formation of the bcc phase-containing metallic glass composite is strongly governed by the alloy composition and the actual cooling rate during solidification. Room-temperature compression tests reveal significant yielding and plastic deformation before failure.
CE combined with rolling circle amplification for sensitive DNA detection (2007)

Here we describe an assay which combines CE with rolling circle amplification (RCA) for sensitive DNA detection and quantification. RCA is an isothermal DNA replication technique that generates a long ssDNA with tandem repeats. It requires simpler temperature control in reaction and offers higher sequence specificity and greater quantitation capability compared to other amplification technologies. In this study, RCA amplified the DNA target via a circular template, and the product was digested into monomers for CE analysis. Less than 2 fmol of the DNA target could easily be detected using this RCA-CE assay and the assay has a dynamic range of two orders of magnitudes. Moreover, simultaneous detection of both the target DNA and the internal standard was achieved by designing two padlock probes with different sizes, which could significantly improve the quantification accuracy. The RCA-CE assay is easy to perform, readily adaptable for detection of multiple targets because of the high resolution power of CE, and is compatible with other applications employing RCA as a signal amplification tool. Additionally, this assay can be used with a capillary array system to perform sensitive, high-throughput genetic screening.
A heterogeneous power efficient load balancing target-monitoring protocol for sensor networks (2010)

A critical aspect of applications with WSNs is increase the sensor nodes lifetime. Power constrained WSNs are useable such as they can communicate sensed data to a processing node. Communication and sensing consume energy therefore energy saving and improving lifetime of WSNs can be achieved by scheduling of sensor nodes. In scheduling allow sensor nodes can interchange its state into idle, sleep and active modes and adjusting the transmission or sensing range. In this paper, we provide a problem formulation for the lifetime maximization problem in WSNs with adjustable sensing ranges for a heterogeneous network model (super, advance and normal nodes). The network lifetime increases with the number of sensors at different targets and sensing range. When number of targets increased, the lifetime of the network decreases as more targets are monitored. The simulation results for target monitoring protocol, HALBPS verify that with the adjustable sensing range, heterogeneous nodes and different targets, the overall network lifetime improved as compared with existing protocols.
Ca2+ causes active contraction of bile canaliculi: direct evidence from microinjection studies. (1984)

Cytoplasmic microinjection of Ca2+ triggers contraction of bile canaliculi in freshly isolated monolayer cultures of rat hepatocytes. Unseparated paired hepatocytes were used to demonstrate this motility-based phenomenon. Only one cell of the pair was injected, but fluorescein spread from the target cell to the opposite cell; also, the contractions were always uniform, equally involving both hepatocytes that form the canaliculus, indicating that communication exists between the cell pairs. Inhibitors of calmodulin and actin filaments, trifluoperazine and cytochalasin B, respectively, inhibited the Ca2+-induced contractions. Hence, the mechanism of contraction has features in common with actin-myosin based cytoplasmic motility behavior found in other non-muscle cells.
Design of a superplastic alloy steel (1974)

An iron alloy, containing a relatively low concentration of alloying elements, which shows good superplastic behaviour in the temperature range 900°–960°C, has been designed from first principles. The alloy, of composition Fe–4%Ni–3%Mo–1·6%Ti, was developed so that at high temperatures it would have a duplex α-γ structure containing approximately equal proportions of the two phases. Grain refinement was achieved by hot rolling in the two-phase field or by cold working and recrystallizing in the two-phase field. At elevated temperatures values of strain-rate sensitivity for the microduplex structure lay in the range 0·5–0·6, and under optimum conditions tensile elongations of >BOO % were obtained. Cavitation occurred during superplastic straining and failure was associated with the growth and interlinkage of cavities. In the air-cooled condition the alloy was fully ferritic and showed good room-temperature tensile properties. A similar alloy which had a lower titanium content and, as a consequence, a larger volume fraction of austenite, did not exhibit such marked superplastic behaviour. Tensile failure was again associated with cavitation but the addition of a trace amount of boron to the alloy led to a marked reduction in the extent of cavitation during deformation.
Brain-Derived Neurotrophic Factor Val/Met Polymorphism and Bipolar Disorder (2008)

These findings suggest that BDNF Val/Met is related to the suicidal behavior of bipolar patients, and may have clinical relevance as a biological indicator of bipolar patients at risk of suicide.
Methylmalonsäure: nur ein (unsicheres) Surrogat - Replik (2009)

Die blichen Normgrenzen, nicht nur fr Vitamin B12, sondern auch fr andere Stoffe, die auf mannigfaltige Art im Krper wirken, wurden statistisch bestimmt, was
Serine Proteases of Malaria Parasite<i>Plasmodium falciparum</i>: Potential as Antimalarial Drug Targets (2014)

Malaria is a major global parasitic disease and a cause of enormous mortality and morbidity. Widespread drug resistance against currently available antimalarials warrants the identification of novel drug targets and development of new drugs. Malarial proteases are a group of molecules that serve as potential drug targets because of their essentiality for parasite life cycle stages and feasibility of designing specific inhibitors against them. Proteases belonging to various mechanistic classes are found in P. falciparum, of which serine proteases are of particular interest due to their involvement in parasite-specific processes of egress and invasion. In P. falciparum, a number of serine proteases belonging to chymotrypsin, subtilisin, and rhomboid clans are found. This review focuses on the potential of P. falciparum serine proteases as antimalarial drug targets.
Effect of low dose recombinant human omega erythropoietin (rHuEPO) on anaemia in patients on hemodialysis. (1995)

The effect of low dose rHuEPO therapy in ESRD patients on regular dialysis therapy was assessed in a prospective study in 22 patients. Routine hematological and biochemical tests, bone marrow aspiration, serum iron and ferritin studies were performed. The quality of life was also assessed. rHuEPO was administered in a dose of 25 units/kg i.v. post dialysis 3 times a week for 8 weeks, followed by 36 units/kg for further 4 weeks. Significant rise (p = 0.0001) in Hb & PCV with rise in reticulocyte count (0.016) was noted. Serum ferritin was a better index of iron status of the body. Significantly improved anemia and quality of life of ESRD patients on hemodialysis was seen in 95% of the patients.
Array calibration by Fourier series parameterization: stochastic maximum likelihood solution (2003)

A truncated Fourier series is proposed to approximate an array's response. Based on this model and a calibration procedure, the log-likelihood function is derived. An antenna array's response was computed using a numerical electromagnetic method. Based on this array response a calibration was simulated. Direct maximization of the log-likelihood function allowed for full azimuthal calibration with low error and required only 40 sources.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Acoustic multipole logging in transversely isotropic poroelastic formations (1989)

The properties of the modes generated by multipole sources in a fluid-filled borehole embedded in (radially layered) formations that include transversely isotropic poroelastic layers are investigated. These layers are modeled following Biot’s and homogenization theories, under the assumption that the principal axes of symmetry of both the transversely isotropic skeleton and the complex permeability tensor are parallel to the vertical axis of the borehole. A general formulation based on the Thomson–Haskell method accounts for any combination of fluid, elastic, and poroelastic layers, either isotropic or transversely isotropic. The investigation is achieved through the computation of dispersion and attenuation curves, and frequency-dependent sensitivity coefficients with respect to the parameters. In the presence of a fast or slow radially semi-infinite transversely isotropic poroelastic formation with an impermeable borehole wall, the shear-wave transverse isotropy of the skeleton can be determined using the low-frequency parts of the fundamental modes generated by a monopole source and one of higher order. With a permeable interface, the fluid flow effects refer to the horizontal mobility (horizontal permeability/saturant fluid viscosity) and disables the determination of the shear-wave transverse isotropy. Without this information, any horizontal mobility determination is incorrect. Whatever the nature of any fluid–poroelastic interface, the presence of radial layering decreases the reliability of any estimation of parameter related to the virgin formation except for the velocity and attenuation of the vertically propagating SV wave. Whatever the configuration, the transverse isotropy of the compressional wave velocity cannot be determined nor can that of the complex permeability tensor or the anelastic attenuation due to the polarization of the (quasi) body waves involved. The results of this work also show that, in contrast to the pure elastic situation, a transverse isotropy of the complex permeability tensor leads to slightly different quasi-SV-wave velocities along the principal directions of propagation at ultrasonic frequencies.
Orthopaedic Implant Technology: Biomaterials from Past to Future (2011)

Orthopaedic implant technology is heavily based on the development and use of biomaterials. These are non-living materials (e.g. metals, polymers and ceramics) that are introduced into the human body as constituents of implants that fulfill or replace some important function. Examples would be prosthetic joint replacements and fracture fixation implants. For orthopaedic biomaterials to succeed in their desired functions and outcomes in the body, a number of factors need to be considered. The most obvious mechanical properties of the implants are that they need to suit their intended function, and various classes and types of biomaterials have been developed and characterised for use in different implant components depending on their demands. Less well understood but no less important are the interactions that occur between the constituent biomaterials and the living cells and tissues, both of the human host as well as pathogens such as bacteria. Biomaterials used for orthopaedic applications are generally considered to be biocompatible. However, adverse effects arising from interactions at the implant interface can result in various modes of implant failure, such as aseptic loosening and implant infection. This review paper uses the illustrative example of total hip replacement (which has been called the operation of the century) to highlight key points in the evolution of orthopaedic biomaterials. It will also examine research strategies that seek to address some of the major problems that orthopaedic implant surgery are facing today.
The Fast Fourier Transform in the Analysis of the Normal Phonocardiogram (1979)

The present study is focused on spectrum analysis as a useful method of processing the PCG in order to obtain the frequency spectral distribution of normal heart sounds. Thirty normal subjects aged from 17 to 34 were studied. PCG was recorded on the fourth intercostal space at the left sternal border using a sound level meter coupled with a standard 6 ml cavity. The microphone had a linear response from 0.2 to 8,000 Hz. The signal was filtered with the standard B network according to the ANSI specifications and was registered on a four track FM tape recorder. A four channel analyzer with a microprocessor for off-line elaborations was used with 10 KHz sampling frequency. The PCG signal was triggered by a QRS detector on the R wave of the simultaneously recorded ECG. Fast Fourier transform was performed employing either a four channel analyzer with a microprocessor, or an A/D converter with a computer. Finally the results of the analysis were statistically elaborated. The described procedures permit to obtain a direct and exact tracing of the acoustic features of the heart, thus representing an attempt to come closer to the standardization and automatic analysis of the phonocardiographic technique.
Study on the formation mechanism of a flat rheology by poly(diethylenetriamine dimer acid amide) and organoclay in nonaqueous drilling fluids over a wide temperature range (2020)

This work aims to establish the relationship between the morphology and rheology changes affected by the addition of Flat-rheology modifier (FRM) to organoclay (OC)/white oil dispersions between 2 and 65 °C to analyze the flat-rheology formation mechanism in nonaqueous drilling fluids. The FRM used in this work is poly(diethylenetriamine dimer acid amide), and the OC is organo-montmorillonite. Temperature-controlled rheological tests confirmed that FRM addition to dispersions with low OC loadings (lower than 3.0 wt%) results in a relatively constant gel strength from 2 to 65 °C. This could be explained by the morphology variations in the dispersions generated by the FRM. Based on macroscopic settlement, particle size distribution, optical microscopy, transmission electron microscopy (TEM) and wide-angle X-ray scattering (WAXS) results, FRM molecules were inserted into and enlarged the interlayer space between OC platelets, thus reducing the particle size and improving the dispersion stability. Subsequently, the original card house network formed by OC particles was destroyed, and a new network with a larger volume fraction was formed by the highly dispersed platelets and FRM molecules. The increase in network volume fraction and extension of FRM molecular carbon chains with increasing temperature inhibit network strength deterioration. As a result, the rheological properties at 65 °C remained similar to those at 2 °C, thereby forming a flat rheology.
DESERCIÓN ESTUDIANTIL EN LA FACULTAD DE MEDICINA DEL INSTITUTO DE CIENCIAS DE LA SALUD, MEDELLIN. 1997 (1997)

Se realizo un estudio de tipo descriptivo retrospectivo sobre la desercion estudiantil en la facultad de Medicina del Instituto de Ciencias de la Salud, CES, entre los anos 1991 - 1996 para identificar sus principales causas (externas a la universidad, internas de la universidad, e intrinsecas del estudiante) debido a la alta tasa de desercion que se presenta en la institucion.
Se entiende por desercion abandonar o desamparar una causa o apelacion que se tenia interpuesta y es el obstaculo mas importante al que se enfrentan alumnos y profesores.
El estudio se realizo a traves de encuestas, a 40 estudiantes que cumplian con los requisitos propuestos por los investigadores (matriculados que no terminaron su semestre academico y estudiantes que culminaron bien su semestre y no se volvieron a matricular)
Se encontro relevante en el estudio la relacion con desercion y pruebas del ICFES; edad al ingreso; aceptacion del curriculum y de la educacion recibida; rendimiento academico y numero de materias perdidas por semestre. Para la mayoria de los estudiantes la causa de retiro mas importante fue psicologica

ABSTRACT
A descriptive retrospective study about student desertion in the Medical School at the Instituto de Ciencias de la Salud CES, between 1991-1996 was done to identify its main causes (university independent, university dependent and student dependent) due to the high rate of abandonment presented in this school.
Desertion means to abandon or quit a cause that was interposed and it is the most important obstacle students and attendings have to face.
The study was made through questionnaires to forty students that fulfilled investigators (enrolled students that didn’’t finish their academic year and students that finished their academic year but never registered again).
A relevant relation between drop-out and the ICFES test; entering age; curriculum acceptance and received education; academic efficiency and number of failled subjects per semester was found. The most important cause of drop-out for students was psychological.
Planning high-carbohydrate, high-fiber diets with a microcomputer. (1983)

Current research suggests that a diet high in carbohydrate and fiber (HCF) may be useful in the management of diabetes mellitus, hypercholesterolemia, and hypertriglyceridemia. To meet the needs of our clinic population, a microcomputer program has been developed that allows for individualization of HCF menu patterns that satisfy both the diet prescription and the patient's preferences. Educational materials were prepared to guide and augment the HCF diet instruction. It is hoped that this comprehensive approach to diet planning and teaching can be applied in similar settings to facilitate the delivery of quality patient care.
Fatal Case of <i>Salmonella enterica</i> subsp. <i>arizonae</i> Gastroenteritis in an Infant with Microcephaly (2003)

Salmonella enterica subsp. arizonae is a common gut inhabitant of reptiles, with snakes as the most common reservoir. Though human cases due to this organism are exceedingly rare, it may infect young infants and immunocompromised individuals with a history of intimate associations with reptiles. Gastroenteritis is the most common presentation; others include peritonitis, pleuritis, osteomyelitis, meningitis, and bacteremia. We report a fatal case of S. enterica subsp. arizonae gastroenteritis in a 3-month-old child with microcephaly, with a review of earlier cases and problems encountered in identification of this rare human pathogen.