gebhart/patrepeval huggingface dataset:
Quantification of Inflammation Within Rabbit Atherosclerotic Plaques Using the Macrophage-Specific CT Contrast Agent N1177: A Comparison with <sup>18</sup>F-FDG PET/CT and Histology (2009)

The intensity of enhancement detected with CT in the aortic wall of rabbits injected with N1177 correlates with intense uptake of (18)F-FDG measured with PET and with macrophage density on histology, suggesting a role for N1177 in noninvasive identification of high-risk atherosclerotic plaques with CT.
Domain Morphology of Star Block Copolymers of Polystyrene and Polyisoprene (1975)

ADVERTISEMENT RETURN TO ISSUEPREVArticleDomain Morphology of Star Block Copolymers of Polystyrene and PolyisopreneLe-Khac Bi and L. J. FettersCite this: Macromolecules 1975, 8, 1, 90–92Publication Date (Print):January 1, 1975Publication History Published online1 May 2002Published inissue 1 January 1975https://pubs.acs.org/doi/10.1021/ma60043a026https://doi.org/10.1021/ma60043a026research-articleACS PublicationsRequest reuse permissionsArticle Views235Altmetric-Citations59LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Targeting the fungal plasma membrane proton pump. (1995)

The need for new mechanistic classes of broad spectrum antifungal agents has prompted development of the membrane sector and ectodomain of the plasma membrane proton pumping ATPase as an antifungal target. The fungal proton pump is a highly abundant, essential enzyme in Saccharomyces cerevisiae. It belongs to the family of P-type ATPases, a class of enzymes that includes the Na+,K(+)-ATPase and the gastric H+,K(+)-ATPase. These enzymes are cell surface therapeutic targets for the cardiac glycosides and several anti-ulcer drugs, respectively. The effects of acid-activated omeprazole show that extensive inhibition of the S. cerevisiae ATPase is fungicidal. Fungal proton pumps possess elements within their transmembrane loops that distinguish them from other P-type ATPases. These loops, such as the conformationally sensitive transmembrane loop 1+2, can attenuate the activity of the enzyme. Expression in S. cerevisiae of fully functional chimeric ATPases that contain a foreign target comprising transmembrane loops 1+2 and/or 3+4 from the fungal pathogen Candida albicans suggests that these loops operate as a domain. The chimera containing C. albicans transmembrane loops 1+2 and 3+4 provides a prototype for mutational analysis of the target region and the screening of inhibitors directed against opportunistic fungal pathogens. Panels of mutants with modified ATPase regulation or with altered cell surface cysteine residues are also described. Information about the ATPase membrane sector and ectodomain has been integrated into a model of this region.
Innovative Concept of a Drilling and/or Production Platform for Operating in Arctic and Deep Water (2007)

A concept of an innovative floating platform using a conical structure was originally developed for operation in arctic region. It is called as MCAD (MonoCone Arctic Drilling Platform). The conical structure is used to reduce ice-loading as it facilitates ice to break in flexure while riding the slope of the conical surface. For supporting the weight of the platform, equipment, and ballast, a base structure with sufficient buoyancy is added at the base of conical structure. To ensure the platform with adequate stability, a heavy (solid) ballasting system that can be lowered to adjust the vertical center of gravity of the platform is incorporated in the system. The conceptual platform configuration has been analyzed for a large payload of more than 25,000 ST operating in approximately 125 feet of water depth. In the winter season, the platform is subjected to more than 12,000 ST of ice load. For warmer season the platform has been designed to survive a 45 feet significant wave height with 80 knots wind, and a very strong current of 6 knots. To withstand such magnitude of ice forces, mooring system using 32 lines was designed. For lower ice loads in a milder environment, the number of mooring lines can be reduced considerably. For operating in the warmer season, the platform was analyzed for design environments of operating and survival conditions. The motion responses in these conditions were found to be excellent in comparison to other deepwater concepts in use. With the promising motion response results of the conceptual platform with such a high payload, the concept is expected to provide operating company an alternative for deepwater application as well. Since the concept has been developed for a very large payload, the excess payload may be utilized as storages of produced oil. Mooring system for operating in deep water has been developed, and has been compared with that of the system for arctic condition. This paper describes the concept identifying the salient features. The effects of various features on the design and platform performance are also described. The ballast system with its lowering system makes this concept attractive for easy installation without the assistance of a large derrick vessel, a significant reduction of installation time is also expected. Results of stability, motion and mooring analyses is presented in the paper as well. Preliminary structural analyses were carried out to confirm the viability of the concept in operational, installation and survival conditions.
Snow ablation modelling in a mature aspen stand of the boreal forest (1998)

Snow ablation modelling at the stand scale must account for the variability in snow cover and the large variations of components of energy transfer at the forest floor. Our previous work successfully predicted snow ablation in a mature jack pine stand by using a one-dimensional snow process model and models predicting radiation below forest canopies. This work represents a second test of our basic modelling scenario by predicting snow ablation in a leafless, deciduous aspen stand and verifying the results with field data. New modifications to the snow model accounted for decreased albedo owing to radiation penetration through optically thin snowpacks. A provisional equation estimates litter fall on the snowpack, thereby reducing the areal averaged albedo. We showed that subcanopy radiation measurements can be used with a canopy model to estimate a branch area index for defoliated aspen as an analogue to the foliage area index used for conifers. Modelled incoming solar and long-wave radiation showed a strong correlation with measurements, with r2=0·96 and 0·91 for solar and long-wave radiation, respectively. Model results demonstrate that net radiation overwhelms turbulent exchanges as the most significant driving force for snowmelt in aspen forests. Predicted snow ablation in the aspen stand compared very favourably with available data on snow depth. © 1998 John Wiley & Sons, Ltd.
Numerical Analysis for Moving Phase Boundary in Finite/Semi-Infinite Multi-phase Diffusion Couple (1993)

Numerical analysis for the calculation of concentration-distance curves in a binary finite/semi-infinite multi-phase diffusion couple based on the forward finite difference method has been proposed. By use of this method concentration-distance curves in the diffusion couple in which more than three diffusion phase layers are formed can be calculated for various periods of anneal time. This method will be useful to investigate disappearance or growth of the diffusion phase layers in the finite/finite or finite/infinite diffusion couple.
A METHOD FOR ISOLATION OF CAMPYLOBACTER SPP. (<i>JEJUNI, COLI AND LARI</i>) FROM SHELLFISH AND THE MARINE ENVIRONMENT (1995)

A method has been developed to detect thermophilic species of Campylobacter in shellfish, marine and tributary waters, sediment and farm runoff by‐products such as manure and silage. The method consists of a 48 h enrichment incubation and subcultured to selective agars. Presumptive colonies confirmed with a latex agglutination (antibodies) to common flagellar antigens of C. jejuni, C. coli and C. lardi. Over an 8 year period, West Coast estuaries (Washington, Oregon, and California) were sampled, resulting in analysis of a total of 512 samples. Results suggest that Campylobacter spp. are well distributed in the marine environment. Two enrichment broths were compared for the recovery of campylobacters from environmental samples. The method described in the Food and Drug Administration Bacteriological Analytical Manual (FDA/BAM) (1984), was compared to a modified method. Use of the modified method described here resulted in higher recovery rates of Campylobacter spp. Recoveries of campylobacters from sediment, shellfish, and water were 10,13, and 28% higher for the modified method, respectively.
Use of Satellite Radar Images in Surveillance and Control of Two Giant Oilfields in California (2001)

A global analysis of the evolution of an entire giant oilfield is now feasible. The oilfield can be viewed as a single complex system consisting of reservoir rock and fluids, and coupled injectors and producers. The vertically averaged areal signatures of primary and waterflood projects in the field can be tracked in time as the displacement of ground surface above these projects. The Synthetic Aperture Radar interferograms (InSAR) from satellites are the enabling technology. In this paper, we add a new element to our multilevel, integrated surveillance and control system: time-lapse satellite InSAR images of the oilfield surface. In particular, we analyze ten differential InSAR images of the South/North Belridge and Lost Hills diatomite fields, CA, between 04/95 and 12/99. The images have been reprocessed and normalized to obtain the ground surface displacement rate. In return, we have been able to calculate section-bysection the net subsidence of ground surface over the entire field areas. The calculated subsidence volumes are thought to be close to the subsidence at the tops of the reservoirs. The images show that the rate of subsidence has decreased in some parts of Lost Hills and Belridge, while it increased in others. Using the production and injection data from the California Conservation Commission and Chevron, we have been able to demonstrate the remarkable behavior of both fields: (1) There is recirculation of injected water through the
Triple neutron correlation for MOX waste assay (1993)

Triple neutron signal correlation techniques were applied to measure the waste in 220-l barrels. Small waste packages weighing 1 to 2 kg originating from a mixed-oxide (MOX) fuel fabrication plant were first measured in a dual range detector head by the plant operator. The correlated pair count rate of each individual package was used together with a calibration constant to determine the effective [sup 240]Pu mass equivalent. A set of such packages was then loaded into a 220-l barrel, keeping the alpha activity well below a prescribed tolerance limit. The task was to verify the [sup 240]Pu equivalent mass content in each barrel for safeguards purposes.
Progress in Device Technology (1998)

A dvances in implantable device technology over the past few years can be seen in these illustrations. The photograph on the left shows a 1997-model implantable cardioverter-defibrillator (ICD) in front of an older version. Beside it is a modern single-chamber pacemaker in front of an older mercury-zinc-cell model. The Table shows their relative weights. These devices are now small enough to permit implantation of both in the same pectoral position, as shown in the photograph on the right. The implanted devices in this case were not the same as the one in the photograph but were of similar vintage. Tomorrow's dual-chamber pacemakers and ICDs will surely be contained in the same "can" and will be smaller still.
Influence of the Doping Level on the Interactions between Poly(3,4‐ethylenedioxythiophene) and Plasmid DNA (2010)

Abstract The influence of the doping level in the formation of specific interactions between plasmid DNA and PEDOT is investigated using experimental assays and theoretical calculations. Electrochemical methods are used to prepare polymer samples with oxidation degrees ranging from 0.14 to 1.05 positive charges per repeating unit. A combination of experimental and theoretical results are used to propose a mechanism for the formation of DNA/conducting polymer complexes, which consists of the initial stabilization of the adducts through non‐specific interactions followed by small structural re‐arrangements that allow to be established specific hydrogen bonds involving the polar groups of the conducting polymer and selected DNA bases. magnified image
Enhancing Effects of High-fat Diet on 3,2'-Dimethyl-4-Aminobiphenyl Urinary Bladder Carcinogenesis in the Hamster. (1996)

Effects of high-fat diet on urinary bladder tumorigenesis in male Syrian golden hamsters caused by 3, 2'-dimethyl-4-aminobiphenyl (DMAB) were analyzed. DMAB was administered i. g. suspended in corn oil at a dose of 100mg/kg b. w. once a week for 20 weeks. Diet supplemented with 5% corn oil was administered throughout the experiment (50 weeks) or for 30 weeks after DMAB treatment. Incidences of DMAB-induced urinary bladder carcinomas were 27% (3/11 animals) in the basal diet group, and 58% (7/12) and 57% (4/7) respectively in the 50 and 30 week high-fat diet groups. The enhancement of bladder carcinogenesis by the high-fat diet was statistically significant by the cumulative chi-square test applied for the sequence of hyperplastic and neoplastic lesions. Thus, corn oil added to the diet increased DMAB-induced bladder carcinogenesis in hamsters.
The Tao of Serials: 101 Things Non-Catalogers Should Know About Serials … or Is It Continuing Resources? (2009)

RecorderSerial catalog records must be interpreted and understood by a wide variety of catalog users: collection development, acquisitions, public services staff, patrons, and even catalogers themselves.This NASIG preconference workshop covered past and current cataloging rules as well as how the applications of these rules are recorded in the MARC 21 format.Key MARC fields were explained, and the presenters demonstrated how some OPACs handle serials-specific information to either the benefit or detriment of catalog users.Also discussed was the expanded definition of continuing resources and how the application of this definition affects cataloging decisions.New standards for next generation catalogs will need to take into account the FRBR (Functional Requirements for Bibliographic Records) conceptual model as well as the development of other metadata content and communication standards beyond both AACR2 and MARC 21.
ICD/ITKE Research Pavilion 2013‐14: Modular Coreless Filament Winding Based on Beetle Elytra (2015)

The ICD/ITKE Research Pavilion 2013‐14, presented here by Moritz Doerstelmann, Jan Knippers, Achim Menges, Stefana Parascho, Marshall Prado and Tobias Schwinn of the Institute for Computational Design (ICD) and Institute of Building Structures and Structural Design (ITKE) research team at the University of Stuttgart, is based on biological lightweight construction principles. It demonstrates how the development of integrative processes of design computation, simulation and robotic fabrication enable the simultaneous exploration of novel design possibilities, constructional effectiveness and robustness through the expression of material characteristics.
Natalizumab (Tysabri®)—Re-defining Efficacy in Multiple Sclerosis—Data from Clinical Trials to Post-marketing Experience (2010)

Multiple sclerosis (MS) is a chronic, disabling condition with severe clinical and social consequences. Current first-line disease-modifying treatments have limited efficacy and do not halt long-term disease progression in the majority of patients. Natalizumab (Tysabri®) is the only monoclonal antibody licensed for use in relapsingremitting MS (RRMS). It is regarded by many neurologists as the most effective MS drug on the market today, and has the potential to re-define successful MS therapy. Its efficacy has been demonstrated both in large-scale clinical trials and in post-marketing settings. Beneficial effects include reduction of relapse rates and disease progression, as well as magnetic resonance imaging (MRI) measures of disease activity. Natalizumab treatment has a substantial impact on patient quality of life. Moreover, patients have shown significant improvement following natalizumab treatment, making continuing clinical remission a realistic goal in MS for the first time. However, the benefits of natalizumab must be balanced against risk. Progressive multifocal leukoencephalopathy (PML) is a rare event associated with natalizumab treatment that may be minimized with a risk management plan to educate physicians on patient selection and management.
Constant Envelope Modulation with Hammerich Transmit Filter (2011)

We propose the Hammerich pulse as a transmit filter for minimum shift keying (HMSK). The spectral properties of HMSK are compared to Gaussian minimum shift keying (GMSK). Furthermore, simulation for coherent demodulation by means of the Laurent approximation and Wiener equalizer are performed in order to compare the bit error rate of both modulation schemes in the AWGN channel.
Minimizing flow-associated noise in electrochemical detectors for liquid chromatography (1982)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTMinimizing flow-associated noise in electrochemical detectors for liquid chromatographyStephen G. WeberCite this: Anal. Chem. 1982, 54, 12, 2126–2127Publication Date (Print):October 1, 1982Publication History Published online1 May 2002Published inissue 1 October 1982https://pubs.acs.org/doi/10.1021/ac00249a056https://doi.org/10.1021/ac00249a056research-articleACS PublicationsRequest reuse permissionsArticle Views57Altmetric-Citations6LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Studies of the Flash Carbonization Process. 2. Violent Ignition Behavior of Pressurized Packed Beds of Biomass:  A Factorial Study (2006)

The Flash Carbonization (FC) process is a novel procedure by which biomass is converted to biocarbon (i.e., charcoal) quickly and efficiently. To begin this process, a canister containing a packed bed of feedstock is placed within a pressure vessel, compressed air is used to charge the system to an initial pressure of ∼1−2 MPa, and a flash fire is ignited at the bottom of the bed. After about two minutes, air is delivered to the top of the bed and the biomass is converted to a high-yield biocarbon. In lab-scale tests, some fuels have been observed to ignite violently, resulting in a sudden drastic pressure rise (ΔP ≈ 1 MPa within 2−3 s). Because this event could be potentially hazardous, a study of this phenomenon was undertaken in preparation for a scale-up of the FC process to a commercial-sized demonstration reactor. The influence of initial pressure, feed moisture content, and ignition heater power were examined following a 23 full factorial experimental design approach. The combined effect of initial pressure and feed moisture content was found to influence the violence of the combustion phenomenon. Additionally, the continued propagation of the initial violent combustion was found to be limited by heat and mass transfer constraints and not by the complete exhaustion of the fuel or oxidizer initially present in the system.
Multivessel coronary spasm as a cause of ischemic syncope in angina at rest* (1982)

Two patients with vasospastic angina at rest developed ST segment elevation both in the anterior and inferior leads during spontaneous and ergonovine-induced attacks. In both cases the acute myocardial ischemia secondary to multivessel coronary spasm led to reversible electromechanical dissociation. Coronary arteriography showed normal coronary arteries in one case and severe three-vessel disease in the other; spasm of the right coronary artery was demonstrated in both patients. These cases show that in patients with vasospastic angina coronary spasm may simultaneously involve different arteries and lead to ischemic electromechanical dissociation. Ergonovine testing is contraindicated in those patients with suspected or proved multivessel coronary spasm.
Real-Time Multibody System Dynamic Simulation: Part II. A Parallel Algorithm and Numerical Results (1991)

ABSTRACT This paper presents a computational algorithm that exploits inherent parallelism in the modified recursive formulation presented in Part I of the paper. Computational data flows to implement the algorithm are defined. By combining the topological analysis method presented in Part 1 of the paper, an efficient general purpose dynamic simulation algorithm is developed. Examples using the code developed show that real-time simulation can be achieved for moderately complex mechanical systems using a shared memory multiprocessor.
Asymmetric coupled transmission lines with anisotropic coupling (2002)

The characteristics of asymmetric coupled transmission lines are derived for the case of general anisotropic coupling, special cases of which are certain geometries of anisotropic materials or from distributed active devices. In addition to deriving the terminal characteristics for the uniform coupled-line, four-port case with anisotropic coupling, it is shown that simplified alternate equivalent expressions for the mode impedances and admittances can be derived. These simplified expressions are useful when examining special cases where a good approximation can be achieved by considering either a generalized anisotropic mutual admittance.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Rearrangement of Allylic and Propargylic Alcohols Catalyzed by the Combined Use of Tetrabutylammonium Perrhenate(VII) and <i>p</i>-Toluenesulfonic Acid (1991)

Abstract Allylic rearrangement and/or dehydration of allylic alcohols proceed by the use of a catalytic amount of tetrabutylammonium perrhenate and p-toluenesulfonic acid. Treatment of propargylic alcohols with the above reagents affords the rearranged products, α,β-unsaturated carbonyl compounds.