gebhart/patrepeval huggingface dataset:
IMPROVING THE REDUCTION OF TIBIAL FRACTURES TREATED BY EXTERNAL FIXATION (2003)

Fractures of the tibia should be reduced as accurately as possible. Fractures opened for internal fixation can be reduced accurately under direct vision, but unstable closed fractures treated by external fixation must be reduced by indirect means. Most surgeons reduce the fracture by manipulation, insert the bone-screws, apply the fixator and then manipulate the fracture again to improve the reduction before locking the fixator. Using this technique it is difficult to obtain a perfect reduction. A poor reduction can prolong healing time and may lead to malunion causing long-term impairment of function. A good reduction lessens the loading imposed on the bone-screws and fixator. We describe a device with which closed tibial fractures can be reduced with a predictable high degree of precision prior to external fixation.

A reduction device, the Staffordshire Orthopaedic Reduction Machine (STORM), was developed. Externally fixed unstable closed tibial fractures reduced by conventional methods (n=37) were compared with those reduced using the STORM (n=41). In the STORM group, the holes for the fixator pins were only drilled once the fracture had been perfectly reduced and no further manipulation was undertaken after the fixator had been applied. Reductions were assessed by measurements of radiographs taken at, and 4 weeks after, fixator removal. All cases were treated with monolateral external fixation.

The STORM significantly improves the precision of reduction of unstable tibial fractures without increasing operating time. Its use obviates the need for reduction joints on external fixators for the tibia.
The Increasing Use of Polypharmacotherapy for Refractory Mood Disorders (2000)

Increasing numbers of medications in more recent NIMH cohorts were required to achieve the same degree of improvement at hospital discharge. More systematic approaches to the complex regimens required for treatment of patients with refractory mood disorder are clearly needed.
Normal Cerebrospinal Fluid Histamine and tele-Methylhistamine Levels in Hypersomnia Conditions (2012)

CSF histamine and tele-methylhistamine did not significantly differ between patients with narcolepsy-cataplexy and other etiologies of non-hypocretin-1 deficient central hypersomnias; these measurements, therefore, are not useful in assessing the etiology or severity of centrally mediated hypersomnia.
Opioids in modulation of experimental pain in a polymodal and tissue differentiated pain model (2005)

440, No. 1226-P96
Pre-filtering improves Prony analysis of disturbance records (2004)

Prony analysis provides resolution of closely spaced multiple modes in signals with high signal to noise ratio. Results are not satisfactory for practical noisy signals recorded during power system disturbances. Attenuation of estimated parameters is the outcome in the case of low signal to noise ratio. This paper presents the application of the smoothing filter for pre-processing signals before using Prony's method. This technique is tested on real power system examples.
The parasympatholytic effects of atropine sulfate and glycopyrrolate in rats and rabbits. (1994)

Nine groups of rats (n = 5 per group) received an intramuscular (IM) injection of one of the following drugs or drug combinations: saline, atropine (0.05 mg/kg), glycopyrrolate (0.5 mg/kg), ketamine:xylazine (85:15 mg/kg), ketamine:detomidine (60:10 mg/kg), atropine:ketamine:xylazine (0.05: 85:15 mg/kg), glycopyrrolate: ketamine:xylazine (0.5:85:15 mg/kg), atropine:ketamine:detomidine (0.05: 60:10 mg/kg) or glycopyrrolate: ketamine:detomidine (0.5:60:10). Similarly six groups of rabbits (n = 5) received an IM injection of either saline, atropine (0.2 mg/kg), atropine (2 mg/kg), glycopyrrolate (0.1 mg/kg), ketamine:xylazine (35:10 mg/kg) or glycopyrrolate:ketamine:xylazine (0.1:35:10 mg/kg). In rats, atropine sulfate (0.05 mg/kg) and glycopyrrolate (0.5 mg/kg) produced an increase in heart rate for 30 and 240 min, respectively. In rabbits atropine sulfate at either 0.2 or 2.0 mg/kg did not induce a significant increase in heart rate, but glycopyrrolate (0.1 mg/kg) elevated the heart rate above saline treated animals for over 50 min. Both atropine and glycopyrrolate provided protection against a decrease in heart rate in rats anesthetized with ketamine: xylazine (85:15 mg/kg) or ketamine: detomidine (60:10 mg/kg); however, glycopyrrolate was significantly more effective in maintaining the heart rate within the normal range. Glycopprrolate also prevented a decrease in heart rate in rabbits anesthetized with ketamine:xylazine (35:5 mg/kg). Neither glycopyrrolate nor atropine influenced respiration rate, core body temperature or systolic blood pressure when used alone or when combined with the injectable anesthetic. Glycopyrrolate is an effective anticholinergic agent in rabbits and rodents and more useful as a preanesthetic agent than atropine sulfate in these animals.
ChemInform Abstract: Glycosyl Imidates. Part 66. Synthesis of the Tetrasaccharide Moiety of Plant Growth Regulator Calonyctin A. (1994)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Preparation of Dithiatetrazocines and Secondary Reactions. (1989)

Abstract The title compounds (IV) are prepared according to the scheme.
Chemistry of heterocyclic compounds. 72. Nicotinic acid crown ethers. An unexpected facile etherification process (1982)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTChemistry of heterocyclic compounds. 72. Nicotinic acid crown ethers. An unexpected facile etherification processGeorge R. Newkome and Hyo Won LeeCite this: J. Org. Chem. 1982, 47, 14, 2800–2802Publication Date (Print):July 1, 1982Publication History Published online1 May 2002Published inissue 1 July 1982https://pubs.acs.org/doi/10.1021/jo00135a029https://doi.org/10.1021/jo00135a029research-articleACS PublicationsRequest reuse permissionsArticle Views220Altmetric-Citations12LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Nd-YAG Laser Resection of Major Airway Tumors : Anesthetic Management Using a Laryngeal Mask Airway Under Total Intravenous Anesthesia. (1998)

気管内腫瘍に対するNd-YAGレーザー焼灼術の麻酔管理では,気道確保,気道内引火,冷却用空気による吸入麻酔薬や吸入酸素濃度の不安定性が問題となる.われわれは声門下1.8cm,4.4cm,6.5cmの部位に転移した気管内悪性腫瘍に対するNd-YAGレーザー焼灼術の麻酔管理をラリンジアルマスクと完全静脈麻酔で行ない良好な結果を得た.ラリンジアルマスクを用いた調節呼吸は,良好な術視野を得る上で有用であった.また,完全静脈麻酔は,吸入酸素濃度を28%で維持することにより気道内引火を予防するとともに,冷却用空気の影響を受けることなく安定した麻酔深度を得る上で有用であった.
Squamous cell carcinoma of the tonsil managed by conventional surgery and postoperative radiation (2014)

Lymphovascular invasion but not pathological stage of the neck is an independent predictor of outcome in patients with tonsillar SCC.
Biosensors and Chromatographic Supports Based on New Combinations of Conductive Materials (1996)

Several approaches towards the optimization of amperometric biosensors using a soluble mediator in combination with reticulated vitreous carbon (RVC) were studied. RVC material was used as the working electrode with biomolecules (enzyme/co-enzyme) immobilised on its surface and intergrated with a FIA system. By using the soluble electron transfer mediator Meldola Blue the oxidation potentials for the electrochemical reactions were reduced, decreasing the interference by compounds that may be oxidised at higher potentials. Electrodes for the determination of glucose, lactate, acetylthiocholine and paraoxon were prepared. The influences of various parameters on the electrode sensitivity were investigated. In a glucose sensor, ferrocene was used as electron transfer mediator together with a conducting polymer (polypyrrole) for electron transport between the enzyme (glucose oxidase) and the electrode surface (RVC). The glucose oxidation was monitored by calorimetry while the system was electrochemically regenerated. The metabolic activity of yeast cells could be monitord by a DC resistometric method using the conducting polymer polypyrrole for immobilisation of the cells. The cobination of superporous agarose gel with electroactive material was used for construction of a chromatographic support material that was both electrically conducting and electrochemically active. A specially designed chromatography column containing this material was connected to a potentiostat and, by changing the applied potential, reduction or oxidation of the support material could be accomplished which influenced the chromatographic properties substantially.
Spin wave generation by surface acoustic waves (2017)

Surface acoustic waves (SAW) on piezoelectric substrates can excite spin wave resonance (SWR) in magnetostrictive films through magnetoelastic coupling. This acoustically driven SWR enables the excitation of a single spin wave mode with an in-plane wave vector k matched to the magnetoelastic wave vector. A 2D frequency domain finite element model is presented that fully couples elastodynamics, micromagnetics, and piezoelectricity with interface spin pumping effects taken into account. It is used to simulate SAW driven SWR on a ferromagnetic and piezoelectric heterostructure device with an interdigital transducer configuration. These results, for the first time, present the spatial distribution of magnetization components that, together with elastic wave, exponentially decays along the propagation direction due to magnetic damping. The results also show that the system transmission rate S21(dB) can be tuned by both an external bias field and the SAW wavevector. Acoustic spin pumping at magnetic film/normal metal interface leads to damping enhancement in magnetic films that decreases the energy absorption rate from elastic energy. This weakened interaction between the magnetic energy and elastic energy leads to a lower evanescence rate of the SAW that results in a longer distance propagation. With strong magnetoelastic coupling, the SAW driven spin wave is able to propagate up to 1200 μm. The results give a quantitative indication of the acoustic spin pumping contribution to linewidth broadening.
Technique de prédistorsion numérique adaptative pour la linéarisation des amplificateurs de puissance micro-ondes (1996)

Techniques de linéarisation numériques -- Classification des techniques de linéarisation -- Techniques analogiques -- Techniques de linéarisation numériques -- Introduction à la technique de prédistorsion numérique adaptive avec la modélisation en temps réel de la non linéarité -- Adaptive digital predistorter for power amplifiers with real time modeling of memoryless complex gains -- The new linearization technique -- Simulation method -- Results -- Technique de prédistorsion adaptative avec modélisation en temps réel (synthèse) -- Synthèse de la technique.
Industrial Marketing Education: Current Status and Future Needs (1983)

The subject of industrial marketing education has been discussed, debated, and written about extensively over the last several decades, but there has been relatively little progress made towards making this topic a significant part of the curriculum in United States business schools. This article is intended to provide a measure of the level of industrial marketing education today, the need for improving that level, and some steps that might be taken toward accomplishing that goal.
<title>Holographically recorded ion-etched variable-line-space gratings</title> (1998)

Variable line space (VLS) diffraction gratings present interesting solutions to design high resolution monochromators for synchrotrons. The problem is to be able to record holographically the desired grooves distribution in order to take advantage of the holographic recording and ion etching process: low stray light, absence of ghosts and second order reduction. We will review the method of calculation of VLS diffraction gratings recorded holographically by using spherical and aspherical laser wavefronts. Then the manufacture of these gratings (accuracy of recording and ion etching process) will be described. We will give an example. And finally, the theory and the accuracy of a checking method will be presented.
Antagonism of the Human Thromboxane A2 Receptor by an Anti-asthmatic Agent AA-2414. (1994)

The human thromboxane A2 receptor (TXA2-R)-coding gene was introduced into Chinese hamster ovary cells and a cell line (TCHO-25) stably expressing TXA2-R, at a level of 3 x 10(5)/cell, was obtained. An anti-asthmatic agent AA-2414 [(+-)-7-(3,5,6-trimethyl-1,4-benzoquinon-2-yl)-7- phenylheptanoic acid] competitively inhibited the specific binding of a TXA2 mimic ([3H]U-46619) to the TCHO-25 cells, with an IC50 of 6.0 x 10(-8) M, indicating that the drug is an antagonist of human TXA2-R. The TCHO-25 cells offer a tool for the screening and characterization of human TXA2-R antagonists.
Usefulness of automatic detection of fragmented red cells using a hematology analyzer for diagnosis of thrombotic microangiopathy (2002)

We previously reported an automatic method for quantitative analysis of schistocytes or fragmented red cells using an automatic hematology analyzer, XE-2100. In the study reported here, we evaluated the accuracy of this detection method in patients with thrombotic microangiopathy (TMA). A follow-up study was performed on 14 patients with two types of TMA, thrombotic thrombocytopenic purpura or hemolytic uremic syndrome. Schistocyte percent was evaluated both with an automatic counter and by means of microscopic observation. Total activity and isoenzyme pattern of lactate dehydrogenase (LD) were also determined. In these patients, schistocyte percent determined by automatic counting correlated highly with that determined by manual counting under microscopic observation (r = 0.852, P < 0.0001). Schistocyte percent was shown to correlate significantly with isoenzyme fractions 1 and 2 of LD (r = 0.732, P < 0.02), reflecting hemolysis. Nine of 11 patients tested had high concentrations of LD isoenzyme five without distinct liver damage, and schistocyte percent did not relate to fraction 5 of LD. Automatic detection of schistocyte percent using a hematology analyzer was useful for an accurate diagnosis and follow-up of thrombotic microangiopathy. The origin of LD fraction 5 remains to be determined.
The 192R/Q polymorphs of serum paraoxonase PON1 differ in HDL binding, lipolactonase stimulation, and cholesterol efflux (2006)

Serum paraoxonase (PON1) is a HDL-associated enzyme exhibiting potentially antiatherogenic properties. Here, we examined the common PON1-192R/Q human polymorphism. Despite numerous studies, the effect of this polymorphism on the antiatherogenic potential of PON1 is yet unresolved. Our structural model suggests that amino acid 192 constitutes part of the HDL-anchoring surface and active site of PON1. Based on our findings that PON1 is an interfacially activated lipolactonase that selectively binds HDL carrying apolipoprotein A-I (apoA-I) and is thereby greatly stabilized and catalytically activated, we examined the interaction of the PON1-192 isozymes with reconstituted HDL-apoA-I particles. We found that PON1 position 192 is indeed involved in HDL binding. The PON1-192Q binds HDL with a 3-fold lower affinity than the R isozyme and consequently exhibits significantly reduced stability, lipolactonase activity, and macrophage cholesterol efflux. We also observed the lower affinity and stability of the 192Q versus the 192R isozyme in sera of individuals belonging to the corresponding genotypes. The observed differences in the properties of PON1-192R/Q isozymes provide a basis for further analysis of the contribution of the 192R/Q polymorphism to the susceptibility to atherosclerosis, although other factors, such as the overall levels of PON1, may play a more significant role.
Deep Levels in CVD Diamond and Their Influence on the Electronic Properties of Diamond-Based Radiation Sensors (2002)

Deep levels in undoped chemical vapor deposited (CVD) diamond films have been characterized by thermally stimulated current spectroscopy (TSC) in the range of 300–650 K. The TSC results have been tentatively correlated to the performance of the samples as on-line dosimeters and particle detectors. The TSC signal is dominated by a set of deep levels with an activation energy in the range of 1.0–1.4 eV. The trapping activity of these levels, which can be related to grain boundaries, strongly influences the detector performance at room temperature. After neutron irradiation up to the fluence of 2 × 1015 n/cm2 the amplitude of the TSC signal decreases of about one order of magnitude, the pumping effect becomes significantly less pronounced and the charge collection efficiency decreases of about 30%. Thus, the radiation-induced removal of these deep levels must be accompanied by the creation of other traps, probably vacancy-related and not visible by TSC in this temperature range, which have little effect on the dynamic response of the device but can affect the charge collection efficiency.
Book Review. Principles of Adsorption and Adsorption Processes (1985)

ADVERTISEMENT RETURN TO ISSUEPREVArticleBook Review. Principles of Adsorption and Adsorption ProcessesShivaji SircarCite this: Langmuir 1985, 1, 4, 529Publication Date (Print):July 1, 1985Publication History Published online7 January 2004Published inissue 1 July 1985https://pubs.acs.org/doi/10.1021/la00064a901https://doi.org/10.1021/la00064a901research-articleACS PublicationsRequest reuse permissionsArticle Views490Altmetric-Citations8LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
CD5+ Follicular Lymphoma (2002)

Follicular lymphoma (FL) is a low-grade lymphoma that typically lacks CD5 antigen expression. We report 3 cases of FL with unusual expression of CD5. All cases showed histologic features of FL, including effaced nodal architecture, follicular growth pattern, and a spectrum of grades from 1 to 3 using World Health Organization criteria. In flow cytometric studies, all 3 cases showed a light chain-restricted, CD19+, CD20+ B-cell population coexpressing CD10 and low-level CD5. Immunohistochemical studies demonstrated an identical B-cell immunophenotype with weak expression of CD5 and coexpression of bcl-2 protein and the germinal center-associated markers, CD10 and bcl-6 protein. None of the cases showed expression of CD43, cyclin D1, or IgD. By molecular analysis, immunoglobulin heavy chain gene rearrangements were demonstrated in all 3 cases, and 2 of 3 cases had a t(14;18). These cases highlight the difficulty classifying these lymphomas by flow cytometric studies alone and emphasize the importance of recognizing FL in the differential diagnosis of CD5+ B-cell lymphomas.
PLASTIC SURGERY FOR MANDIBULAR RETRUSION (1950)

From the Department of Plastic Surgery, Johns Hopkins Hospital and Johns Hopkins University School of Medicine.
Heat treatment enhances the plant phenolic (+)-catechin, a weak antimicrobial agent when combined with copper sulphate (2015)

The aim of the study was to compare the antimicrobial activities of freshly-made, heat-treated (HT), and 14 d stored (+)-Catechin solutions with (+)-catechin flavanol isomers in the presence of copper sulphate. (+)-Catechin activity was investigated when combined with different ratios of Cu(2+) ; 100°C heat treatment; autoclaving; and 14 d storage against Staphylococcus aureus. Cu(2+) -(+)-Catechin complexation, isomer structure-activity relationships, and H2 O2 generation were also investigated. Freshly-made, HT, and 14d stored flavanols showed no activity. Whilst combined Cu(2+) -autoclaved (+)-Catechin and -HT(+)-Catechin activities were similar, HT(+)-Catechin was more active than either freshly-made (+)-catechin (generating more H2 O2 ) or (-)-Epicatechin (though it generated less H2 O2 ) or 14d-(+)-Catechin (which had similar activity to Cu(2+) controls - though it generated more H2 O2 ). When combined with Cu(2+) , in terms of rates of activity, HT(+)-Catechin was lower than (-)-Epigallocatechin gallate and greater than freshly-made (+)-Catechin. Freshly-made and HT(+)-Catechin formed acidic complexes with Cu(2+) as indicated by pH and UV-vis measurements although pH changes did not account for antimicrobial activity. Freshly-made and HT(+)-Catechin both formed Cu(2+) complexes. The HT(+)-Catechin complex generated more H2 O2 which could explain its higher antimicrobial activity. This article is protected by copyright. All rights reserved.
Antimetabolite Suppression of Corneal Hypersensitivity (1965)

The corneal homograft reaction, like the rejection of other homotransplanted tissues and organs, is an immune response of the host to the donor cornea. The precise nature of this immune response, however, is not entirely clear. At the risk of oversimplification, it is useful to divide all immunological reactions into two classes. The first includes all states of hypersensitivity which seem to have their basis in immunologically competent, bloodborne, mononuclear cells. This group of immune phenomena is referred to as delayed hypersensitivity. The second general class of immunological reactions is mediated by circulating humoral antibodies; this group is referred to as immediate hypersensitivity. We may assume, therefore, that the homograft reaction in the cornea or elsewhere has one of three etiologic mechanisms. First, the antigen of the graft may stimulate the production of immunologically competent lymphoid cells which, in turn, leave their site of origin and enter the grafted foreign
Vanishing fluctuations in atomic spectra (1991)

Spectral fluctuations are discussed in the context of the K-matrix theory of interacting autoionizing resonances. New measurements of the doubly-excited spectrum of Ba I in the vicinity of the 6p1/2 threshold provide unambiguous evidence for the disappearance of fluctuations at a specific excitation energy well below the associated series limit. The authors discuss the origin of this effect, and show that it occurs close to the resonance energy of one broad intruder level, and also suggest a more general connection between the vanishing width effect and the disappearance of fluctuations in atomic spectra.