gebhart/patrepeval huggingface dataset:
Adaptive progressive download based on the MPEG-4 file format (2006)

In this paper we describe how progressive download and adaptive streaming can be combined into a simple and efficient streaming framework. Based on the MPEG-4 file format (MP4) we use HTTP for transport and argue that these two components are sufficient for specifying an open streaming architecture. The client selects appropriate chunks from the MP4 file to be transferred based on (1) the header information (i.e. the “moov” box) in the first part of the file and (2) his observation of network throughput. The framework is completely client driven which allows for better server scalability and reduces signalling overhead. We discuss architecture and implementation issues such as complexity, interoperability and scalability and compare to 3GPP PSS Rel-6 adaptive streaming when appropriate. Measurements from a simple MP4/HTTP streaming client are presented showing that appropriate chunks are selected such that increased reliability is achieved.
Anti‐peroxidase antibody‐secreting hybrid lines. I. Identification, cloning and cell characterization (1979)

Anti-peroxidase antibody (Ab)-secreting hybrids have been produced by fusion of peroxidase (PO)-immunized mouse lymph node cells and immunoglobulin (Ig)-secreting P3-X63-Ag8 (X63) myeloma cells. Identification of Ab-secreting hybrids can be performed as early as day 5 after cell fusion by the hemolytic plaque assay. Immediately after identification, hybrids were directly isolated, by means of a micropipette, into Terasaki microchambers containing nutrient medium and a thymocyte filler layer. The yield of secreting hybrids is improved by using this procedure. All the cells of the PO 772 C2 clone show the same ultrastructural pattern and immunocytological properties; they are proplasmocytes, as are the parental X63 cells; they present intracisternae Ab and show no Ig or Fc receptors at the cell surface. Over 90% of viable PO 772 C2 cells form specific plaques. Isoelectric focusing and sodium dodecyl sulfate polyacrylamide gel electrophoresis show that the cells of this clone secrete Ab; the secreted Ig are formed with chi and gamma 1 chains from the parental X63 cells and specific L and H chains from the lymphoid parent. These biological investigations demonstrate the relative stability of the PO 772 C2 clone secreting anti-peroxidase antibody.
High speed reflectometer for EUV mask-blanks (2005)

AIXUV GmbH and partners have developed a high speed Reflectometer for EUV mask-blanks which is fully compliant with the SEMI-standard P38 for EUV-mask-blank metrology. The system has been installed in June 2004 at SCHOTT Lithotec AG. It features high throughput, high lateral and spectral resolution, high reproduci-bility and low absolute uncertainty. Using AIXUV's EUV-LAMP and debris mitigation, low cost-of-ownership and high availability is expected. The spectral reflectance of up to 3 mask-blanks per hour can be measured with at least 20 spots each. The system is push button-controlled. Results are stored in CSV file format. For a spot size of 0.1×1 mm<sup>2</sup>, 2000 spectral chan-nels of 1.6 pm bandwidth are recorded from 11.6 nm to 14.8 nm. The reflectance measurement is based on the comparison of the sample under test to two reference mirrors calibrated at the PTB radiometry laboratory at BESSY II. The three reflection spectra are recorded simultaneously. For each spot more than 107 photons are ac-cumulated in about 20 s, providing statistical reproducibility below 0.2 % RMS. The total uncertainty is below 0.5 % absolute. Wavelength calibration better than 1 pm RMS over the whole spectral range is achieved by refe-rence to NIST published wavelengths of about 100 xenon emission lines. It is consistent with the wavelength of the krypton 3d-5p absorption resonance at 13.5947 nm to better than 2 pm.
Sylvian aqueduct syndrome and global rostral midbrain dysfunction associated with shunt malfunction (1999)

It is probable that in obstructive hydrocephalus, at the time of shunt malfunction, the development of a transtentorial pressure gradient could initially induce a functional impairment of the upper midbrain, inducing upward gaze palsy. The persistence of the gradient could lead to a global dysfunction of the upper midbrain. Third ventriculostomy contributes to equalization of cerebrospinal fluid pressure across the tentorium by restoring free communication between the infratentorial and supratentorial compartments, resulting in resolution of the patient's clinical symptoms.
Rubella Virus Neutralization by Plaque Reduction. (1967)

The hemadsorption-negative plaque assay technique has provided a means of quantitatively studying rubella virus neutralization. A 3-day assay for rubella antibodies has been developed which is sensitive and reproducible. The addition of fresh guinea pig serum enhanced rubella antibody titers up to 16 times those obtained in heated sera. The factor or factors responsible for the enhancement of antibody titers have the properties of complement.
From Drug Screening to Target Deconvolution: a Target-Based Drug Discovery Pipeline Using Leishmania Casein Kinase 1 Isoform 2 To Identify Compounds with Antileishmanial Activity (2016)

Existing therapies for leishmaniases present significant limitations, such as toxic side effects, and are rendered inefficient by parasite resistance. It is of utmost importance to develop novel drugs targeting Leishmania that take these two limitations into consideration. We thus chose a target-based approach using an exoprotein kinase, Leishmania casein kinase 1.2 (LmCK1.2) that was recently shown to be essential for intracellular parasite survival and infectivity. We developed a four-step pipeline to identify novel selective antileishmanial compounds. In step 1, we screened 5,018 compounds from kinase-biased libraries with Leishmania and mammalian CK1 in order to identify hit compounds and assess their specificity. For step 2, we selected 88 compounds among those with the lowest 50% inhibitory concentration to test their biological activity on host-free parasites using a resazurin reduction assay and on intramacrophagic amastigotes using a high content phenotypic assay. Only 75 compounds showed antileishmanial activity and were retained for step 3 to evaluate their toxicity against mouse macrophages and human cell lines. The four compounds that displayed a selectivity index above 10 were then assessed for their affinity to LmCK1.2 using a target deconvolution strategy in step 4. Finally, we retained two compounds, PP2 and compound 42, for which LmCK1.2 seems to be the primary target. Using this four-step pipeline, we identify from several thousand molecules, two lead compounds with a selective antileishmanial activity.
De Dysphonia Severity Index: een objectieve maat Voor de stemkwaliteit (2000)

De Dysphonia Severity Index (DSI) modelleert de stemkwaliteit van een patient, met het oog op het weerspiegelen van de gepercipieerde stemkwaliteit door middel van objectieve en kwantitatieve metingen. De DSI is gebaseerd op een gewogen combinatie van geselecteerde stemparameters: de hoogste frequentie (Fo-High in Hz), de laagste intensiteit (I-Low in dB), de maximale fonatietijd (MPT ins) en de jitter (%). Deze DSI is het resultaat van een multivariate analyse van stemmen van 387 personen en wordt als volgt berekend (Wuyts, F. L. et al., 2000): DSI = 0.13 * MPT + 0.0053 * Fo-High – 0.26* I-Low – 1.18 * Jitter (%) + 12.4, De DSI voor perceptueel normaal klinkende stemmen is +5 en voor ernstiggestoorde stemmen -5. Hoe negatiever een index is, des te slechter is de stemkwaliteit van de patient. Daardoor is de DSIeen instrument dat zich goed leent voor het evalueren van een therapie bij een patient met een hese stem. Daarnaast bestaatereen goede correlatie met de Voice Handicap Index score, die de psychosociale impact van het stemprobleem zoals door de patient wordt ervaren, weerspiegelt.
InP HBT amplifier MMICs operating to 0.67 THz (2013)

Two indium-phosphide (InP) double-heterojunction bipolar transistor (DHBT) based terahertz monolithic integrated circuit (TMIC) amplifiers are reported with record operating bandwidths up to 694 GHz. The first amplifier uses 3 μm long emitter transistors, has 24 dB gain at 670 GHz, and a saturated output power of -4 dBm at 585 GHz. The second amplifier uses 6 μm long emitter transistors, has 20 dB gain at 655 GHz, and a saturated output power of -0.7 dBm at 585 GHz. Both TMICs use Teledyne's 130nm InP DHBT transistors in a common base configuration and are matched using inverted CPW transmission lines realized using a three-metal-layer high-density thin-film interconnects system. These results demonstrate the capability of 130nm InP DHBT technology to enable sophisticated TMIC circuits for operation in the terahertz band.
CYP2A6 slow nicotine metabolism is associated with increased quitting by adolescent smokers (2013)

Variation in the CYP2A6 gene, which decreases the rate of nicotine metabolic inactivation, is associated with higher adult smoking cessation rates during clinical trials. We hypothesized that slow metabolism is associated with increased quitting during adolescence. White adolescent smokers (N=308, aged 12-17, 36.3% male) from a cohort study were genotyped for CYP2A6, resulting in 7.8% slow, 14.0% intermediate and 78.2% normal metabolizers. Overall, 144 smokers quit smoking, as indicated by being abstinent for at least 12 months. In logistic regression analyses, the odds ratio for quitting was 2.25 (95% confidence interval 1.05, 4.80; P=0.037) for slow metabolizers relative to normal metabolizers. A linear trend toward increased quitting with decreasing CYP2A6 activity was also observed (odds ratio=1.44, 95% confidence interval 1.02, 2.01; P=0.034). Thus, CYP2A6 slow metabolism is associated with increased adolescent smoking cessation, indicating that even early in the smoking history, genetic variation is influencing smoking cessation.
Comparison of continuous flow analysis techniques: A laboratory exercise (1989)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTComparison of continuous flow analysis techniques: A laboratory exerciseC. L. M. Stults , Paul R. Kraus , S. K. Ratanathanawongs , Chas. J. Patton , and S. R. Crouch Cite this: J. Chem. Educ. 1989, 66, 12, 1060Publication Date (Print):December 1, 1989Publication History Received3 August 2009Published online1 December 1989Published inissue 1 December 1989https://doi.org/10.1021/ed066p1060RIGHTS & PERMISSIONSArticle Views95Altmetric-Citations4LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (2 MB) Get e-Alerts Get e-Alerts
Expression of two different FMOs in sheep liver. (1998)

Five different members of the flavin-dependent monooxygenase gene family from different animal species have been described to date. We report the purification and characterization of two FMOs from sheep liver. The predominant isoform was purified 240-fold and was homogenous in SDS PAGE. Its molecular weight (MW) was 58 KDa. The N-terminal sequence, the cross-reactivity with anti-rat FMO3 antibodies, and the catalytic properties such the ability to metabolize trimethylamine (TMA) and to stereoselectively produce L-methionine-d-sulfoxide from L-methionine, are all consistent with this protein being an FMO3. The minor form has a MW of 59 KDa and cross-reacts with anti-rat FMO1 antibodies. The methimazole S-oxidase activity catalyzed by this form was not inhibited by TMA but was inhibited by imipramine. These facts imply that this protein is an FMO1. The expression profile of FMO in sheep liver is similar to that in the human or the mouse but differs from the rat profile.
An integrated RF MEMS tunable filter (2012)

This paper reports on a high-performance MEMS lumped bandpass filter continuously tuned from 1 GHz to 0.6 GHz using 12 electrostatically actuated MEMS capacitors. To demonstrate the benefits of MEMS technologies, a reconfigurable filter array is implemented on a PCB using SMT components and its performance is compared to that of the MEMS filter. Besides the advantage in size, the MEMS filter also exhibits lower loss and greater rejection. To become a viable solution for RF applications, other performance specifications of MEMS filters such as tuning speed and reliability need to be improved.
Apnea–hypopnea index in nonobese women with polycystic ovary syndrome (2009)

PCOS was directly linked to increased obstructive respiratory events during sleep in nonobese women in Taiwan.
Synthesis of Functionalized Pyridazin-3(2<i>H</i>)-ones via Selective Bromine–Magnesium Exchange and Lactam Directed Ortho C–H Magnesiation (2011)

Selective bromine-magnesium exchange on 2-benzyl-5-bromo-4-methoxypyridazin-3(2H)-one could be achieved when MesMgBr was used as reagent. With more nucleophilic RMgCl species (R = Bu, i-Pr, Ph) both nucleophilic addition-elimination at C-4 and bromine-magnesium exchange at C-5 occurred. In 2-benzyl-5-bromopyridazin-3(2H)-one, which does not contain a substituent at C-4, addition could not be suppressed. Less nucleophilic Mg amides (TMPMgCl·LiCl) allowed regioselective C-H magnesiation at the C-4 position in such substrates, as exemplified for 2-benzyl-5-chloro- and 2-benzyl-6-chloropyridazin-3(2H)-one. Quenching of the magnesiated pyridazinones with electrophiles gives access to a variety of hitherto unknown pyridazin-3(2H)-one derivatives.
Liquid CO<sub>2</sub> as a Safe and Benign Solvent for the Ozonolysis of Fatty Acid Methyl Esters (2015)

We have shown that liquid CO2 dissolves O3 in higher concentrations compared to conventional solvents and is therefore an effective medium for the ozonolysis of unsaturated compounds. The Beer–Lambert law extinction coefficient for ozone in liquid CO2 is determined to be 3.2 ± 0.3 M–1 cm–1. Further, the Henry’s law coefficient for ozone dissolution in dense phase CO2 is determined to be on the order of 0.25 mol L–1 bar–1 in the temperature range −10 to +4 °C. Rapid ozonolysis of methyl oleate in liquid CO2 has been successfully demonstrated with the 1,2,4-trioxolanes (secondary ozonides) being the major stable product, as confirmed by NMR analysis. The product distribution is consistent with a lack of solvent cage effects due to the low polarity of liquid CO2. In addition to the inertness of liquid CO2 to ozone attack, the dominant presence of dense CO2 in the vapor phase promotes inherent process safety.
Fabrication and properties of SmFe<sub>2</sub>-PZT magnetoelectric thin films (2013)

Magnetoelectric (ME) thin film composites are attracting a continually increasing interest due to their unique features and potential applications in multifunctional microdevices and integrated units such as sensors, actuators and energy harvesting modules. By combining piezoelectric and highly magnetostrictive thin films, the potentialities of these materials increase. In this paper we report the fabrication of SmFe<sub>2</sub> and PZT thin films and the investigation of their properties. First of all, a ~ 400 nm thin SmFe film was deposited on top of Si/SiO<sub>2</sub> substrate by magnetron sputter deposition. Afterwards, a 140 nm Pt bottom electrode was sputtered on top of the SmFe film forming a bottom electrode. Spin coating was employed for the deposition of the 150 nm thin PZT layer. A PZT solution with 10 %Pb excess was utilized for this fabrication step. Finally, circular Pt top electrodes were sputtered as top electrodes. This paper focuses on the microstructure of the individual films characterized by X-Ray diffractometer (XRD) and scanning electron microscopy (SEM). A piezoelectric evaluation system, aixPES, with TF2000E analyzer component was used for the electric hysteresis measurements of PZT thin films and a vibrating sample magnetometer (VSM) was employed for the magnetic characterization of the SmFe. The developed thin films and the fabricated double layer SmFe-PZT exhibit both good ferromagnetic and piezoelectric responses which predict a promising ME composite structure. The quantitative chemical composition of the samples was confirmed by energy dispersive spectroscopy (EDX).
Utilizing lexical data from a Web-derived corpus to expand productive collocation knowledge (2009)

Abstract Collocations are of great importance for second language learners, and a learner’s knowledge of them plays a key role in producing language fluently (Nation, 2001: 323). In this article we describe and evaluate an innovative system that uses a Web-derived corpus and digital library software to produce a vast concordance and present it in a way that helps students use collocations more effectively in their writing. Instead of live search we use an off-line corpus of short sequences of words, along with their frequencies. They are preprocessed, filtered, and organized into a searchable digital library collection containing 380 million five-word sequences drawn from a vocabulary of 145,000 words. Although the phrases are short, learners can browse more extended contexts because the system automatically locates sample sentences that contain them, either on the Web or in the British National Corpus. Two evaluations were conducted: an expert user tested the system to see if it could generate suitable alternatives for given text fragments, and students used it for a particular exercise. Both suggest that, even within the constraints of a limited study, the system could and did help students improve their writing.
Nano-Enabled Smart Chemiresistors for Improved Chemical Sensing. (2007)

Abstract not provided.
Personal documentation and information system for engineers (1989)

Enumerates the information explosion environment and the findings of past research on information gathering patterns of engineers, presents basic concepts of documentation, information and personal documentation and information system, stresses the need for systematic management of personal documentation and information system, explains briefly the various principles, procedures and processes involved in developing and managing personal documentation and information system and concludes by calling for little investment of time and energy on the part of engineers to develop and maintain scientific personal documentation and information systems to derive enormous benefits to the organisations and individuals.
Rock creek multiple coal streams project. Final report, July 1984-November 1994 (1995)

Pyridoxine, at dosages known to be safe from previous studies (<250 mg/day) can restore migratory ability and shear stress response to endothelial cells cultured in high-glucose conditions. This indicates that pyridoxine is a potential candidate for treatment of diabetic ulcers and atherosclerosis in diabetes due to the link between these pathologies and endothelial dysfunction in diabetes.
ICONE15-10781 HEAT TRANSFER IN HELIUM-COOLED STORAGE BASKET FOR SPENT PWR FUEL RODS (2007)

The Environmental Technology grows nowadays to play an important role, so the storage technique for nuclear spent fuel is a key to supporting the reactor safety against the environmentalists. This paper addresses the thermal conduction in solid fuel, the thermal natural convection due to buoyancy and thermal radiation by using the commercial Computational Fluid Dynamics solver, Fluent 6 in the helium-cooled storage basket for nuclear reactor spent fuel rods. This study finds out the maximum temperature of the rods under the steady state balancing the total heat transfer rate, in addition, how much the radiation affects the overall heat transfer rate is envisaged. The basket contains the total 15x15 element rod fuel bundle. The decay heat generated on rod surface is transferred through the inner basket plate wall. The surface-to-surface model is selected as thermal radiation model. The helium contained and sealed initially inside the canister tank is treated as Boussinesq approximation assuming incompressible fluids in an enclosure sealed completely. Therefore, the overall solution process is carried out under steady state solution. The emissivity is constant as 0.8 for the fuel rod and 0.3 for the inner plate and other wall according to verification and validation assessments in Pacific Northwest Laboratory. And the calculation results are compared with that of experimentation. The deviation temperature differences are turned out to be a limited temperature more or less. The temperature gradient in radial direction of the basket shows the good agreement with the experiment. Almost of all heat power generated from the bundle is transferred via buoyancy coupled with thermal radiative heat transfer, here the ratio of thermal radiation is dependent on the emissivity. Temperature on basket surface affects the bundle temperature in basket. The total heat transfer rate of the fuel bundles is shared as natural circulation and thermal radiation, the heat balance sheet confirms the convergency of steady state approaching of calculations.
Developing a course about nano-packaging (2005)

This paper describes the students' education in electronics packaging at Dresden University of Technology, Germany. Beginning with a summary about the general model and the existing lectures it is shown, how step by step the knowledge about the topics of producing electronic modules is improved and also combined with practical experiences and skills. Following this a brief section shows the recent developments in packaging. This leads to the necessity to enhance the courses contents to these leading-edge developments to well the students up for their upcoming business. Finally the concept of a course offered for graduate students and dealing with topics around nano-packaging is introduced.
Grain-Boundary Migration and Cavitation during Fatigue (1968)

AbstractAbstractHigh-purity copper, magnesium, and Magnox AL80 have been fatigued at temperatures of 0.5T m and above. Grain-boundary migration and cavitation were observed after fatigue, and quantitative measurements of the angular distributions of total and cavitated boundaries were made. These showed that grain boundaries tended to migrate to planes of maximum shear stress during fatigue, the driving force most probably being provided by the imbalance of dislocations across boundaries due to inhomogeneity of slip. Similarly, the incidence of cavitated boundaries showed a maximum around the planes of maximum shear stress. The results support the theory of the growth of cavities by absorption of lattice vacancies continuously generated in the grains by alternating plastic strain.
Identification of pollutant gases from an atmospheric mixture using high resolution Dispersive Fourier Transformation Spectroscopy (2008)

Dispersive Fourier Transformation Spectroscopy technique allows us to accurately measure the refractive index and absorption coefficient of pollutant gases over a wide range of frequencies from 0.3 - 0.9 Thz. This spectrum can be used to identify and detect a gas in a mixture. In this study, the absorption and refractive index data of carbon monoxide mixed with air is presented. The peaks observed in the data set show similar trends with the dielectric data of atmospheric and carbon monoxide gases measured separately.