gebhart/patrepeval huggingface dataset:
Normalization of Platelet Survival in an Experimental Model after Platelet Exposure of Thrombin in Vitro or adp in Vivo (1977)

It is generally assumed that when platelets are damaged during preparation, their subsequent survival in the circulation is decreased. We have examined the effect of exposure of platelets to stimuli such as thrombin and ADP prior to studying their interaction with either damaged vessel wall or in vivo aggregation by infused collagen. Catheters inserted in the abdominal aorta of rabbits produced marked vascular damage. This was associated with a significant shortening of platelet half life (T½) of homologous 51Cr-labelled platelets (T½-18hrs: Control animals T½-34hrs). In contrast, the platelet half lives of platelets degranulated by thrombin in vitro and those harvested from donors treated with ADP in vivo were 23 and 30 hrs respectively. In vivo collagen-induced platelet aggregation of the thrombin degranulated and the ADP exposed platelets was also found to be significantly diminished when compared with those obtained from untreated control animals. These results suggest that exposure of platelets to either exogenous or endogenous stimuli could possibly mask a reduction in platelet survival in thrombovascular disorders and its modification by drugs.
Zur Stereochemie der thermischen Fragmentierung von Hydrazonderivaten substituierter N‐Amino‐aziridine. Vorläufige Mitteilung (1970)

Abstract The thermally induced fragmentations of the hydrazones derived from phenylglyoxal and the diastereomeric 2,3‐diphenyl‐1‐amino‐aziridines and 2,3‐dimethyl‐1‐amino‐aziridines proceed with high stereospecificity.
Two-stage stochastic power generation scheduling in microgrids (2014)

In this study, the power scheduling problem in μ-grids is investigated taking the uncertainties in power demand and wind power into account. The problem is formulated as a stochastic mixed-integer linear optimization problem with the objective being minimizing the total μ-grid cost. The objective is subject to a set of operational constraints imposed on the generating units and the system itself. A two-stage stochastic programming method has been applied to find the optimal power generation schedule for a μ-grid. The developed approach was implemented in a General Algebraic Modeling System platform (GAMS). The developed method was tested on a μ-grid consisting of eight dispatchable units and a wind turbine. To demonstrate the necessity of uncertainty modeling, the value of the stochastic solution (VSS) and the expected value of perfect information (EVPI) were used to compare the stochastic power schedule obtained with the deterministic one.
ChemInform Abstract: Mono Alcohols, Glycols, and Their Ethers and Esters by CO Hydrogenation (1994)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Optical heterodyne strain sensor (1981)

It has been demonstrated that heteordyne optical strain sensing can be used to measure both static and vibratory strains to a range of 2000 microstrain with a sensitivity approaching one microstrain and an accuracy approaching one percent. The theoretical and experimental work undertaken to develop a heteordyne optical strain sensing system, as described herein, includes: 1) the fabrication of a prototype device; 2) a system evaluation study; and 3) application to a beam, turbine blade and crack detection. In addition to a detailed discussion of the results, the principles of heterodyne optical strain measurements, as originally conceived at the United Technologies Research Center, are presented. (Author)
Basic Study on laser Oscillator and Characteristics of Beam. Study on Materials Processing by High Peak Short Pulse CO2 Laser. Report 1. (1992)

It is very difficult to obtain high quality without cracks and charring by heat affection in the field of materials processing on ceramics or fibre reinforced plastics (FRP) by conventional CO2 laser owing to its low peak power and long pulse duration.
Disseminated Rhinovirus C8 Infection with Infectious Virus in Blood and Fatal Outcome in a Child with Repeated Episodes of Bronchiolitis (2015)

We report a fatal case of acute lower respiratory tract disease with human rhinovirus C (HRV-C) as the unique cause in a 19-month-old girl with a history of repeated episodes of bronchiolitis. HRV-C type 8 nucleic acids were observed in respiratory, stool, and cerebrospinal fluid samples, and infectious virions were isolated from patient serum after inoculation onto reconstituted airway epithelia.
ChemInform Abstract: RK. VON ACETYLEN MIT ORGANISCHEN DISULFIDEN 5. MITT. EINFLUSS DER RK.‐BEDINGUNGEN AUF AUSBEUTEN UND ANTEILE MOEGLICHER RK.‐PRODUKTE (1971)

Abstract Die Addition des Disulfids (I) an Acetylen (II) in Gegenwart von 10 Gew.% (bezogen auf das Disulfid) K‐tert.‐butylat oder 10 Gew.% KOH bei 110‐120°C liefert bei einer Disulfid‐Konversion von 97 bzw. 80% Gemische der Addukte (III) (Ausbeute 25 bzw. 49%) und (IV) (63 bzw. 36%).
Plasmonic Nanostructures: Tuning Dichroic Plasmon Resonance Modes of Gold Nanoparticles in Optical Thin Films (Adv. Funct. Mater. 13/2013) (2013)

On page 1655 Angel Barranco, Agustín R. Gonzalez-Elipe, and co-workers report the synthesis of asymmetric gold plasmonic nanostructures along the tilted intercolumnar space of SiO2 thin films prepared at glancing deposition angles. The film dichroism, evidenced by changing the light polarization and/or sample orientation, can be lithographically removed using a nanosecond laser for the development of advanced optical encryption patterns at micro-macroscales.
The OYSTER Open Source Project for Introducing Entity Resolution and MDM into Information Systems Curricula. (2018)

Entity resolution (ER), or record linking, is foundational for identity management, master data management (MDM), and data integration. Even though these topics may be covered in various parts of an IS curriculum, these modules often lack a hands-on component because appropriate software is easily available. Even when an IT vendor provides an educational license, students are exposed to only one design and implementation ER and MDM. OYSTER is an open source Java platform written specifically to support teaching and research in entity resolution, identity management, and MDM. OYSTER has been used to teach a graduate-level course in ER each year since 2010 and has been downloaded from SourceForge.net thousands of times. \\ \\ Some of the features supported in the current 3.5 version of the software (now resident on BitBucket.net) are deterministic (Boolean) matching, probabilistic (scoring) matching at both the attribute and value level, list matching, property-value pair list matching, and multivalued attributes matrix matching. It also supports inverted index match key blocking on multiple match keys. In addition to basic deduplication (merge-purge linking) operation, the software also supports the full life cycle of identity management from identity capture through identity update and assertions for knowledgebase (graph) maintenance. All of the oyster features and functions are configurable through three XML scripts executed at run time. \\ \\ New features, bug fixes, and documentation updates are continually being added by the OYSTER development team. New features in development include a logistic regression match rule and a probabilistic weight calculator. The system comes with documentation and a set of pre-configured scripts and test data to help students learn the basic operation of the system and fundamentals of ER. Instructors can also request a set of 4 files (272K records) comprising synthetic customer occupancy data. These files can be used as the basis for a team Ã¢â¬ÅchallengeÃ¢â¬Â project to link all of the same customer records within and across files. Because the challenge data was synthetically generated, teams can easily check the precision and recall of their linking results at any time through a web service that scores the results against the correct linking. \\ \\ The talk will include lessons learned from using OYSTER in classes, textbooks available for covering ER and MDM topics, ideas for improving student experience with the system, and an invitation to contribute to OYSTER development and lesson development. \\
La nostra sicurezza e la privacy dei criminali (2019)

Le piattaforme digitali applicano codici crittografici inviolabili e non vogliono fornire accesso alle forze dell’ordine per difendere la privacy. Ma in questo modo lasciano spazio alle reti della criminalità e dei pedofili. Ora persino un potente servizio segreto Usa riconosce che queste aziende stanno diventando più potenti dello Stato. E propone loro un patto. Vogliamo davvero che lo Stato abdichi il suo ruolo di controllo?
FM noise reduction and subkilohertz linewidth of an AlGaAs laser by negative electrical feedback (1990)

Negative electrical feedback was applied to a CSP-type AlGaAs laser, reducing its FM noise at the Fourier frequency range of f<or=40 MHz. The magnitude of the FM noise was far lower than the quantum noise level of the free-running laser at 100 Hz<or=f<or=4.4 MHz. It was as low as 1*10/sup -7/ approximately 1*10/sup -6/ that of the free-running laser at 100 Hz<or=f<or=1 kHz. The full width at half maximum of the field spectrum was reduced to 560 Hz. The major factors necessary for realizing the very low FM noise level were: (1) the laser had almost constant FM response characteristics for a wide Fourier frequency range; (2) a high-finesse Fabry-Perot interferometer was employed for highly-sensitive FM noise detection and to get higher feedback gain; (3) the reflection mode of the Fabry-Perot interferometer was employed to increase the bandwidth and efficiency of the FM noise detection; and (4) a computer simulation was utilized for optimum design of the feedback loop.<<ETX>>
4‐Methylumbelliferyl 5‐Acetamido‐3,4,5‐trideoxy‐α‐<scp>D</scp>‐<i>manno</i>‐2‐nonulopyranosidonic Acid: Synthesis and Resistance to Bacterial Sialidases (1986)

Abstract The synthesis of 4‐methylumbelliferyl α‐ D ‐glycoside 13 of N ‐acetyl‐4‐deoxyneuraminic acid and its behaviour towards bacterial sialidases is described. N ‐Acetyl‐4‐deoxyneuraminic acid ( 1 ) was transformed into its methyl ester 2 and then acetylated to give the anomeric pentaacetates 3 and 4 of methyl 4‐deoxyneuraminate and the enolacetate 5 ( Scheme ). A mixture 3/4 was treated with HCl/AcCl to give the glycosyl chloride, which was directly converted into the 4‐methylumbelliferyl α‐ D ‐glycoside 9 of methyl 7‐ O ,8‐ O ,9‐ O , N ‐tetraacetylneuraminate and into the 2,3‐dehydrosialic acid 11 . The ketoside 9 was de‐ O ‐acetylated to 12 with NaOMe in MeOH. Saponification (NaOH) of the methyl ester 12 followed by acidification gave the free 13 , which was also converted into the sodium salt 14 by passage through Dowex 50 (Na + ). The 4‐deoxy α‐ D ‐glycoside 13 is not hydrolyzed at significant rates by Vibrio cholerae and Arthrobacter ureafaciens sialidase. Neither the free N ‐acetyl‐4‐deoxyneuraminic acid ( 1 ), nor the α‐ D ‐glycoside 13 inhibit the activity of these sialidases.
ChemInform Abstract: CROWN‐CATION COMPLEX EFFECTS. IV. CROWN ETHER AND QUATERNARY ION MEDIATED DISPLACEMENTS IN ARYLDIAZONIUM COMPOUNDS (1977)

Abstract Die Umsetzung von Diazoniumsalzen (I) zu den Folgeprodukten (III) und (IV) wird in Gegenwart von Benzyltrimethylammoniumsalzen oder von Kronenäthern untersucht.
Appendix C - Planar transmission lines (2019)

The Appendix discusses: microstrip transmission line design, discontinuity compensation, dielectric covered microstrip lines, twin strip transmission lines, and parallel plate transmission lines. Chapter Contents: C.1 Microstrip transmission line design C.2 Discontinuity compensation C.3 Dielectric covered microstrip line C.4 Twin strip transmission line C.5 Parallel plate transmission line References Inspec keywords: transmission line theory; microstrip lines Other keywords: twin strip transmission lines; discontinuity compensation; parallel plate transmission lines; dielectric covered microstrip lines; microstrip transmission line Subjects: Waveguides and microwave transmission lines; Transmission line theory
The Mechanism Of The Desire Process (1987)

Multilayer resist techniques have been studied for several years already. Especially with the trilayer systems very good results can be obtained, but only at the expense of added complexity. Their complexity has caused some reluctance to implement these techniques into IC manufacturing lines. Using the PLASMASK resist in the so called DESIRE process, even better performance can be obtained, without any of the disadvantages of multilayer techniques. The process is based on a silylation which results from the selective diffusion of a silylating agent into the resist matrix. The basic chemistry that enables this differentiation in diffusion is discussed, as well as the principle advantages of the diffusion-controlled process.
Faculty Opinions recommendation of Hypermutability and error catastrophe due to defects in ribonucleotide reductase. (2013)

The enzyme ribonucleotide reductase (RNR) plays a critical role in the production of deoxynucleoside-5'-triphosphates (dNTPs), the building blocks for DNA synthesis and replication. The levels of the cellular dNTPs are tightly controlled, in large part through allosteric control of RNR. One important reason for controlling the dNTPs relates to their ability to affect the fidelity of DNA replication and, hence, the cellular mutation rate. We have previously isolated a set of mutants of Escherichia coli RNR that are characterized by altered dNTP pools and increased mutation rates (mutator mutants). Here, we show that one particular set of RNR mutants, carrying alterations at the enzyme's allosteric specificity site, is characterized by relatively modest dNTP pool deviations but exceptionally strong mutator phenotypes, when measured in a mutational forward assay (>1,000-fold increases). We provide evidence indicating that this high mutability is due to a saturation of the DNA mismatch repair system, leading to hypermutability and error catastrophe. The results indicate that, surprisingly, even modest deviations of the cellular dNTP pools, particularly when the pool deviations promote particular types of replication errors, can have dramatic consequences for mutation rates. PMID: 24167285 Funding information This work was supported by: Intramural NIH HHS, United States NIEHS NIH HHS, United States Grant ID: Z01 ES065086
Cardiovascular Effects and Placental Passage of Dantrolene in the Maternal-Fetal Sheep Model (1988)

The effects of dantrolene on skeletal muscle when used for the control of malignant hyperthermia are well known. Since dantrolene may also alter the function of smooth and cardiac muscles, the safety of the drug during pregnancy was investigated in a maternal-fetal sheep model.
Antibacterial effect of cotton fabric treated with silver nanoparticles of different sizes and shapes (2019)

Silver nanoparticles have an extremely large specifi c surface area, which increases when in contact with bacteria, viruses, and fungi. This signifi cantly increases their bactericidal activity by decreasing the sizes of silver nanoparticles and by increasing their surface area to volume ratio
Anti-glycation Effect of Gold Nanoparticles on Collagen (2012)

Gold nanoparticles (GNPs) have been reported to exhibit a variety of biological effects including anti-inflammatory and anti-oxidant activities. The extent of an in vitro glycation reaction mixture of collagen and glycolaldehyde was assayed to investigate the inhibition of glycolaldehye-derived advanced glycation end products (glycol-AGEs) formation with GNPs in collagen, which is a major protein component of the human dermis. GNP-treated collagen showed significantly less glycation (56.3 ± 4.2%) than an untreated glycation control. Moreover, GNP-treated glycation in a collagen lattice model significantly decreased the AGEs distribution in the model system. Taken together, these results suggest that GNPs have the potential for use in the prevention of glycation-induced skin aging.
Optical metrology of a large deformable aspherical mirror using software configurable optical test system (2014)

The software configurable optical test system (SCOTS) is an efficient metrology technology based on reflection deflectometry that uses only a liquid-crystal display and a camera to measure surface slope. The surface slope is determined by triangulation using the co-ordinates of the display screen, camera, and test mirror. We present our SCOTS test results concentrated on high dynamic range measurements of low order aberrations. The varying astigmatism in the 910-mm diameter aspheric deformable secondary mirror for the large binocular telescope was measured with SCOTS, requiring no null corrector. The SCOTS system was designed on-axis with camera and screen aligned on the optical axis of the test mirror with the help of a 6-inch pellicle beam splitter. The on-axis design provides better control of the astigmatism in the test. The high dynamic range of the slope provided a measurement of astigmatism within 0.2-μm root-mean-square accuracy in the presence of 231-μm peak-to-valley aspheric departure. The simplicity of the test allowed the measurements to be performed at multiple gravity angles.
High‐content drug screening for rare diseases (2017)

Per definition, rare diseases affect only a small number of subjects within a given population. Taken together however, they represent a considerable medical burden, which remains poorly addressed in terms of treatment. Compared to other diseases, obstacles to the development of therapies for rare diseases include less extensive physiopathology knowledge, limited number of patients to test treatments, and poor commercial interest from the industry. Recently, advances in high-throughput and high-content screening (HTS and HCS) have been fostered by the development of specific routines that use robot- and computer-assisted technologies to automatize tasks, allowing screening of a large number of compounds in a short period of time, using experimental model of diseases. These approaches are particularly relevant for drug repositioning in rare disease, which restricts the search to compounds that have already been tested in humans, thereby reducing the need for extensive preclinical tests. In the future, these same tools, combined with computational modeling and artificial neural network analyses, may also be used to predict individual clinical responses to drugs in a personalized medicine approach.
Accurate quantitation ofLeishmania infection in cultured cells by flow cytometry (2000)

The FCM assay provided rapid quantitation of Leishmania infection either in mouse macrophages, the natural host cell in murine leishmaniasis, or in Chinese hamster ovary (CHO) cells, a non-macrophage cell line proposed as an in vitro model for studying host-parasite interactions. The protocol described here should be adaptable to studies involving other parasites residing in nucleated cells.
ChemInform Abstract: para‐Selective Fries Rearrangement of Phenyl Acetate in the Presence of Zeolite Molecular Sieves. (1989)

Abstract The thermolysis of phenyl acetate (I) is performed in the presence of various zeolites at 170 or 210°C, yielding the acetyl phenols (II) and (III), p‐acetylphenyl acetate (IV), and phenol (V).
Groove Pancreatitis. A Mini-Series Report and Review of the Literature (2015)

Groove pancreatitis can present in a similar fashion to head of pancreas cancer and chronic pancreatitis. For this reason it is paramount for clinicians to be aware of groove pancreatitis, as this can lead to the correct diagnosis and management of this unique disease.
[Dynamic renal echography versus urography in the follow-up of patients who have undergone ureterosigmoidostomy]. (1994)

The main post uretero-sigmoidostomy complications are stricture of the anastomosis, chronic infection and urolithiasis. In our institution the patients with ureterosigmodostomy undergo a follow-up protocol in which blood chemistry, ultrasonography, intravenous pyelography and C.T. are periodically performed. The aim of the present paper is to compare the accuracy of kidney sonography after diuretic stimulation with intravenous pyelography in the diagnosis of ureteral stenosis. Out of 91 patient with ureterosigmoidostomy 18 patients (34 kidneys) underwent intravenous pyelography, a basal U.S. and then a dynamic one at 5, 10, 15, 30, 45, 60, 90, 120 minutes after administration of furosemide 20 mg i.v. At basal U.S. 27 kidneys were normal and 7 showed a dilations. After diuretic stimulation we observed 16 normal kidneys, 16 dilated units and 2 intermittent hydronephrosis. Out of 16 dilated kidneys 6 became normal in 60 minutes. Out of 10 dilated units 3 were normal in 90 minutes (hipotonic), 2 were normal before 120 minutes (low grade obstruction) and 5 were dilated after 120 minutes (high grade obstruction). With intravenous pyelography we observed 27 normal kidneys and seven dilated units. Dynamic sonography have shown high sensibility (100%), specificity (88.8%) and accuracy (91%) in diagnosis of ureteral obstruction in to I.V.P. in the follow-up of this kind of divesion.
Multimodal reflectivity of CRIGF filters: First experimental observation and modelling (2015)

Cavity Resonator Integrated Guided-mode Resonance Filter (CRIGF) are a new class of filtering reflectors whose selected wavelength and spectral width are independent of the angle of incidence unlike GMRF. These particular properties allow both compactness and a high angular acceptance. However, ours studies show that CRIGFs offer simultaneously spectral and modal filtering and we evidence high-spatial-order reflected modes. In this paper, we will present characterization of the spectral and spatial profile that demonstrates the existence of these high-order modes. In addition, we will present a model based on the physical understanding of implied phenomena to explain the experimental results. This model combines coupled-mode modelling and moiré fringes analysis. These modes could be harnessed for simultaneous spatial and spectral laser stabilization, to design and fabricate selective reflectors or outcouplers for spatial mode division multiplexing (SMDM) in few-mode fibers (FMFs) or for particles optical trapping.