gebhart/patrepeval huggingface dataset:
Cerebral Hemodynamics in Subarachnoid Hemorrhage Evaluated by Transcranial Doppler Sonography. Part 2. Pulsatility Indices (1993)

In previous publications on the diagnostic value of transcranial Doppler sonography (TCD), conflicting results concerning predictive capacities for evaluating vasospasm by measuring flow velocities were reported, and the necessity to examine pulsatility indices (PIs) was stressed. PIs are known to give useful information on cerebral hemodynamics in cases of stenosis of the extracranial internal carotid artery and cerebral arteriovenous malformations. Whether the examination of PIs can give additional information in cases of subarachnoid hemorrhage (SAH) and allow prediction of impending delayed ischemic deficits (DIDs) is still unclear. Normal reference values for the Gosling pulsatility index, the Pourcelot resistance index, and the first Fourier pulsatility index were established in a series of 97 normal subjects. A significant increase in the indices was found as age increased, and there was a strong relation between the indices. There were no statistically significant differences between the right and left sides. An inverse relation was found between the flow velocity and PIs in the middle cerebral artery. In a prospective study of 455 follow-up TCD examinations in 66 SAH patients treated routinely with nimodipine, three different groups were analyzed separately: Group I, patients without DIDs; Group II, patients with DIDs; and Group III, patients with neurological deficits not strictly classifiable as DIDs. The analysis of all three groups together showed a typical time course after the onset of SAH: initially elevated PIs normalized around the tenth day after bleeding. According to Fisher grading, the amount of subarachnoid blood influences the increase in PIs significantly.(ABSTRACT TRUNCATED AT 250 WORDS)
Minimum fault coverage in reconfigurable arrays (2003)

The authors discuss the case in which the redundant elements are arranged in the form of spare rows and spare columns for a rectangular array. Redundant RAMs are examples of such case. A covering is set of rows and columns that are to be replaced by spare rows and spare columns so that all defective elements are replaced. The authors introduce the notion of a critical set, which is a maximum set of rows and columns that must be included in any minimum covering. They show that for a given pattern of defective elements the corresponding critical set is unique. They also present a polynomial-time algorithm for finding the critical set and demonstrate how the concept of critical sets can be used to solve a number of fault-coverage problems.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Understanding and Servicing CD Players (1994)

INCLUDE: Basic principles of CD technology Basic CD player Optical assemblies Focus servo Tracking servo Carriage servo Disc or spindle motor servo Decoder System control Power supplies Fault diagnosis Adjustments
A Theoretical Analysis of the Viscous Flow in a Narrowly Spaced Radial Diffuser (1957)

Abstract A theoretical method for calculating the radial pressure distribution for laminar viscous flow in a narrowly spaced radial diffuser having arbitrarily shaped walls deviating only moderately from a plane surface is developed. The analysis as it stands is also directly applicable to turbulent flow in the initial inlet region of a diffuser. Additional work is necessary to obtain a complete turbulent-flow analysis. Pressure distributions calculated by the laminar-flow theory show reasonably good agreement with the limited experimental pressure distributions available at the time of the analysis. Fairly good agreement also is obtained for the performance of a disk-valve element.
The Effect of Amitriptyline on Ectopic Discharge of Primary Afferent Fibers in the L5 Dorsal Root in a Rat Model of Neuropathic Pain (2009)

These results provide direct evidence that amitriptyline, which is used clinically for the treatment of neuropathic pain, selectively inhibits ectopic discharge of low frequency and bursting discharge in the rat neuropathic pain model.
Damage Localization Based on Power Spectral Density Analysis (2007)

An environmental excitation having random characteristics may be more effective and cost-efficient than other excitation means for non-destructive damage identification purpose on most of the large-scale engineering structures under operation. In general, many existing damage indexes are constructed based on the modal properties derived firstly from the power spectral density (PSD) analysis of the structures under random excitation. However, the derivation procedures for the modal parameters usually introduce some extra errors into the indexes. This paper aims to propose a simple and feasible damage location index (DLI) constructed directly derived from the analysis results of the structural response PSD. The performance of DLI was verified using an aluminum beam with fixed ends and an experimental reinforced concrete (RC) beam under free boundary condition. Our results show that the damage location of the aluminum beam can be determined via the plot of DLI value by selecting the peaks with the amplitudes exceeding a predefined threshold value in both single- and multi-damaged scenarios. And the index may also predict the possible damage zones in the RC beam experimentally tested.
T-Lymphocyte Lines Specific for Glutamic Acid Decarboxylase (GAD) the 64K β-Cell Antigen of IDDM (1992)

Insulin-dependent diabetes mellitus (IDDM) is viewed as a thymus-dependent autoimmune disease, although the specific beta-cell autoantigen or autoantigens remain unknown. The recent identification of the beta-cell 64K antigen as the enzyme glutamic acid decarboxylase (GAD) permits investigation of GAD as a candidate for the autoantigen associated with beta-cell destruction, mediated by T-lymphocytes, in susceptible individuals. In this study, we describe the isolation of GAD-specific T-lymphocyte lines from BB rats, an animal model of IDDM. GAD (Escherichia coli) was inoculated into the footpads of diabetes-resistant BB rats, and after 10 days, a popliteal lymph node cell culture suspension was prepared. GAD-specific T lymphocytes were obtained by culture with interleukin 2 and repeated stimulation with GAD in the presence of BB rat thymic antigen-presenting cells. Four stable, CD4+, MHC (RT1u)-restricted T-lymphocyte lines were isolated. They proliferate selectively in the presence of GAD and secrete interleukin 2 and interferon-gamma. T-lymphocyte lines such as these could be important in the definition of pathogenetic epitopes associated with GAD.
Enzymatic Vitreolysis with Ocriplasmin for Vitreomacular Traction and Macular Holes (2012)

Intravitreal injection of the vitreolytic agent ocriplasmin resolved vitreomacular traction and closed macular holes in significantly more patients than did injection of placebo and was associated with a higher incidence of ocular adverse events, which were mainly transient. (Funded by ThromboGenics; ClinicalTrials.gov numbers, NCT00781859 and NCT00798317.).
Precise Eye Detection From Image Sequences (1998)

Publication in the conference proceedings of EUSIPCO, Rhodes, Greece, 1998
Generalization of symmetric α-stable Lévy distributions for q&gt;1 (2010)

The alpha-stable distributions introduced by Lévy play an important role in probabilistic theoretical studies and their various applications, e.g., in statistical physics, life sciences, and economics. In the present paper we study sequences of long-range dependent random variables whose distributions have asymptotic power-law decay, and which are called (q,alpha)-stable distributions. These sequences are generalizations of independent and identically distributed alpha-stable distributions and have not been previously studied. Long-range dependent (q,alpha)-stable distributions might arise in the description of anomalous processes in nonextensive statistical mechanics, cell biology, finance. The parameter q controls dependence. If q=1 then they are classical independent and identically distributed with alpha-stable Lévy distributions. In the present paper we establish basic properties of (q,alpha)-stable distributions and generalize the result of Umarov et al. [Milan J. Math. 76, 307 (2008)], where the particular case alpha=2,q[1,3) was considered, to the whole range of stability and nonextensivity parameters alpha(0,2] and q[1,3), respectively. We also discuss possible further extensions of the results that we obtain and formulate some conjectures.
Users' guides to the medical literature. II. How to use an article about therapy or prevention. A. Are the results of the study valid? Evidence-Based Medicine Working Group (1993)

<h3>CLINICAL SCENARIO</h3> You are working as an internal medicine resident in a rheumatology rotation and are seeing a 19-year-old woman who has had systemic lupus erythematosus diagnosed on the basis of a characteristic skin rash, arthritis, and renal disease. A renal biopsy has shown diffuse proliferative nephritis. A year ago her creatinine level was 140 μmol/L, 6 months ago it was 180 μmol/L, and in a blood sample taken a week before this clinic visit, 220 μmol/L. Over the last year she has been taking prednisone, and over the last 6 months, cyclophosphamide, both in appropriate doses. You are distressed by the rising creatinine level and the rheumatology fellow with whom you discuss the problem suggests that you contact the hematology service to consider a trial of plasmapheresis. The fellow states that plasmapheresis is effective in reducing the level of the antibodies responsible for the nephritis and cites a number
Synthesis of Chitosan-Based Molecularly Imprinted Polymers for Pre-Concentration and Clean-up of Chloramphenicol (2014)

Chitosan-based molecularly imprinted polymers (CHI-MIPs) were prepared under optimized conditions using chloramphenicol (CAP) as template molecule, acrylamide as functional monomer and CHI as functional matrix. The influences of template molecule and concentrations of functional monomer as well as imprinting conditions on the binding properties of the MIPs were analyzed. The adsorption properties were evaluated by kinetic binding experiments, static binding experiments and Scatchard analysis, which indicated that the synthesized polymers had high binding capacity. Results of competitive recognition studies showed that the imprinting factor of CAP was found to be 7.43, which was much higher than those of its analogues. Solidphase extraction (SPE) using the prepared CHI-MIPs as sorbents was then applied to selectively extract CAP from spiked honey and milk samples. The average recoveries of SPE were in the range of 94.96–100.58% with relative standard deviation less than 5%.
The reduction of fiber-fed echelle spectrograph data: Methods and an IDL-based solution procedure (1994)

Echelle spectrograph data present several challenges in data reduction. In this paper we address the general problem of accurately extracting spectra from a night's worth of raw CCD fiber-fed echelle data frames. We first briefly review echelle spectroscopy: properties of the basic echelle spectrograph, how the orders are arranged on the CCD, and what demands and constraints this data format places on reduction algorithms. We then discuss solutions to the various problems for fiber-fed data, with particular emphasison the removal of the scattered light background. Finally, we discuss our implementation of these solutions. We have written a package using the Interactive Data Language (IDL) that uses the methods described in this paper to give accurate extractions of spectra from fiber-fed echelle frames with any number of spectral orders of arbitrary tilt and curvature. We describe how interested persons may obtain the package through anonymous FTP.
Efficacy and Safety of Hair-Coloring Agents (1994)

Overview | The leading peer-reviewed scientific journal in contact dermatitis, and the only journal in its field that publishes leading research in atopic, contact, occupational, environmental, and drug dermatitis.
Adjusting for regression toward the mean when variables are normally distributed (1997)

Many studies use the same variable, for example blood pressure in studies of antihypertensive treatments, to identify subjects to be included in the study and to evaluate the effects of a treatment. As a consequence, if not properly accounted for, the effect of regression toward the mean can confound the evaluation of treatment effects if the study has no randomized control group. In this paper we review the methods that have been proposed for adjusting for the effect of regression toward the mean when the variable of interest is assumed to be normally distributed. Maximum likelihood estimation and moment-based estimation are considered, including more recent methods which can be applied when repeated measurements on each subject are available.
Symptom Description and Management in Narcolepsy (1996)

Narcolepsy is a neurologic condition that is chronic and lifelong. The study reported describes the experience of living with the most prevalent symptoms of narcolepsy and the management strategies employed for those symptoms by persons with narcolepsy. Descriptions of living with excessive daytime sleepiness, sleep attacks, and cataplexy are given. Nonpharmacologic strategies for symptom management were described by 63.2% of the study participants for cataplexy, 54.5% for sleep attacks, and 35.5% for excessive daytime sleepiness. Specific management and coping strategies are provided.
Quasi-Monte Carlo method for calculating X-ray scatter in CT (2021)

In this paper we transform the trajectories of X-ray as it interacts with a phantom into a high-dimensional integration problem and give the integral formula for the probability of photons emitted from the X-ray source through the phantom to reach the detector. We propose a superior algorithm called gQMCFRD, which combines GPU-based quasi-Monte Carlo (gQMC) method with forced random detection (FRD) technique to simulate this integral. QMC simulation is deterministic versions of Monte Carlo (MC) simulation, which uses deterministic low discrepancy points (such as Sobol' points) instead of the random points. By using the QMC and FRD technique, the gQMCFRD greatly increases the simulation convergence rate and efficiency. We benchmark gQMCFRD, GPU based MC tool (gMCDRR), which performs conventional simulations, a GPU-based Metropolis MC tool (gMMC), which uses the Metropolis-Hasting algorithm to sample the entire photon path from the X-ray source to the detector and gMCFRD, that uses random points for sampling against PENELOPE subroutines: MC-GPU. The results are in excellent agreement and the Efficiency Improvement Factor range 27 ∼ 37 (or 1.09 ∼ 1.16, or 0.12 ∼ 0.15, or 3.62 ∼ 3.70) by gQMCFRD (or gMCDRR, or gMMC, or gMCFRD) with comparison to MC-GPU in all cases. It shows that gQMCFRD is more effective in these cases.
Effect of retinoids on the growth, ultrastructure, and cytoskeletal structures of malignant rat osteoblasts. (1985)

A clonal rat osteogenic sarcoma cell line, UMR 106-06, was used to study the effects of retinoic acid (RA) on its growth and morphology. Retinoic acid caused a reversible, time and dose-dependent inhibition of growth. RA-treated cells were larger, were more adherent to the substratum, and contained fewer mitotic figures. Half-maximal growth inhibition was observed at 10(-8) M. Among the naturally occurring retinoids, RA was clearly the most potent while the arotinoids, Ro 13-7410 and Ro 13-6298, were approximately 50 times more potent than was RA. A similar range of potencies was observed in the cloning efficiencies of the cells in soft agar. Fluorescence microscopy revealed that RA treatment increased the cellular content and organization of F-actin fibers. Ultrastructural changes include decreased chromatin dispersion and increased number of nucleoli per nucleus, decreased rough endoplasmic reticulum, decreased electron density and number of mitochondria, and increased formation of microfilaments and microtubules. These results identify this clonal cell line, which has been extensively characterized as the malignant counterpart of the normal osteoblast, as a target for vitamin A action.
Functional Analysis of the Murine LI-Cadherin Promoter (2004)

The LI-cadherin (cadherin-17) is a structurally divergent member of the cadherin superfamily, with seven rather than five extracellular cadherin repeats, exclusively expressed in the small and large intestine but not in the upper gastric tract. Although lacking from the healthy gastric epithelia, LI- cadherin becomes strongly expressed during intestinal metaplasia and in gastric adenocarcinomas. In this thesis, the first analysis of the mechanisms regulating murine and human LI-cadherin expression was performed. The transcriptional start site was identified by 5'-RACE and primer extension analysis. Activity of 2.8 kb of the 5'-flanking region was tested with luciferase reporter gene constructs in gastrointestinal cell lines. A comparison of the human and murine 5'-flanking region revealed putative binding sites for the transcription factors Cdx2, HNF-1, AP-1, Sp1 and GATA-1, 2, 3.. The Cdx2 and HNF-1 binding sites were both conserved in mouse and human, while the GC-box was only found in the murine 5'-flanking region. Deletion analysis was used to identify regions of the LI-cadherin promoter required for activity in transfected intestinal cells. The results indicated that promoter activity was dependent on positive regulatory elements located within only 55 nucleotides directly upstream of the transcriptional start site. EMSA and supershift assays identified the hepatocyte nuclear factor HNF-1 and Sp1 as interacting factors within this region. Further upstream, the intestine-specific homeodomain protein Cdx2 was found to interact with the promoter. Mutational analysis demonstrated a positive regulatory role for HNF-1 and Cdx2. While the GC-box was lacking in the human sequence, function in mouse was indicated through mutational analysis of the murine GC-box in reporter gene assays.
Literatura y TIC: book-trailer como herramienta educativa (2017)

The advance of digital technologies has changed education, the teaching and learning processes and the way we approach literary texts. This paper presents an analysis of how the Internet has transformed literacy and has promoted the emergence of new digital genres. Literacy has been changed through multimodality – it refers to the use of several resources in different formats (images, texts, music, video, among others) integrated in a new text, creating new forms of expression and communication. An example of multimodality is the book-trailer, which is a visual representation of a book in a similar way to a movie trailer, and it can be considered as an example of good practice in education, allowing the integration of several codes and promoting students´motivation.
The International Law Standard in Treaties of the United States (1954)

Journal Article The International Law Standard in Treaties of the United States Get access The International Law Standard in Treaties of the United States. By Robert Renbert Wilson. Cambridge, Mass., Harvard University Press; London, Oxford University Press, 1953. xii+321 pp. Bibliog. Index. 812′​′×5′​′⁠. $4.50. 30s. R. Y. J. R. Y. J. Search for other works by this author on: Oxford Academic Google Scholar International Affairs, Volume 30, Issue 2, April 1954, Pages 204–205, https://doi.org/10.2307/2607530 Published: 01 April 1954
Bearing Damage Detection of BLDC Motors Based on Current Envelope Analysis (2012)

We’ve built this digital research platform to provide academics everywhere with fast, stable and secure digital access to our library of over 110,000 scholarly books and 800,000 journal articles. We’ve tested the platform in close cooperation with leading academic institutions. If you have any questions or you notice something doesn’t quite work as it should, please visit our <a href="/publishing/faq?lang=en" class="text-primary">Help/FAQ</a> page and let us know.
Liquid biopsy for minimally invasive heart transplant monitoring: a pilot study (2019)

There is a undeniable need for an alternative, non-invasive diagnostic procedure of early transplant rejection and investigation of donor-derived cell-free DNA seems to be the promising choice. The very high sensitivity is particularly enticing to consider liquid biopsy as a potential screening tool. Its minimal invasiveness may allow for more frequent examination and, thus, tighter monitoring. The reliable assessment of its clinical utility requires an adequately powered and properly designed multicentre study.
Lester R. Dragstedt (1988)

Lester Dragstedt was born in anaconda, Montana, the son of Swedish immigrant parents. His entire college and professional education took place at the University of Chicago, where he received a B.S. degree in 1915, a master's degree in physiology in 1916, a Ph.D. in physiology in 1920, and the M.D. degree (from Rush) in 1921. His first academic appointment was as a physiologist at the State University of Iowa. In 1925 Dragstedt was recruited by Dallas B. Phemister to help design the new University Hospital research facilities on the campus of the University of Chicago. Following completion of this responsibility Phemister appointed Dragstedt as Associate Professor of Surgery, stating, “I can teach surgery to a physiologist; I am interested in teaching physiology to surgeons.” In 1947 Dragstedt succeeded Phemister as chairman, a post he occupied until his retirement in 1959. Dragstedt was regarded as a skilled clinician as well as a dexterous and artistic surgeon. But he was particularly recognized for his contributions as physiologist-surgeon in the treatment of diseases of the pancreas, parathyroids, and especially diseases of the stomach. In 1943, he performed a transthoracic vagotomy on a patient with a duodenal ulcer who refused to accept the standard operation, subtotal gastrectomy. A lesser known but classical work of Dragstedt and his coworkers is reproduced here for this series. Dragstedt was the originator of the skin-grafted ileostomy in the treatment of ulcerative colitis. The author describes a complete “take” of the split-thickness graft in four patients, although he observed that the “resulting ileostomy looked somewhat like a penis.” One can only surmise about the psychologic disability that would be produced. The stoma could, however, be fitted with an appliance that would minimize the risk of abdominal wall digestion. When reading the article and understanding the experimental studies proposing the possible causative organism of ulcerative colitis, one is impressed by Dragstedt's creative thinking. Dragstedt's renown as a basic scientist was illustrated by his election to the National Academy of Sciences. Following his Chicago retirement he became again a full-time physiologist with appointments as research professor in both the department of surgery and the department of physiology at the University of Florida College of Medicine. Active until the end, he died at his summer home on Elk Lake, Michigan on July 16, 1975.
Toxic Contaminants in Harvested Forages (1997)

Harvested forages are vitally important and commonly used for beef production.But contamination can occur which results in reduced forage quality and palatability or may even result in animal illness and death.Outlined below are some of the common problems that should be considered. QUALITYForage quality is affected primarily by moisture damage, maturity at harvest, and contamination with other plants.The effect is reduced protein, energy and vitamin content.Under some conditions, toxins or poisons may also be produced.