gebhart/patrepeval huggingface dataset:
Study of the Polymerization of Methyl Methacrylate Initiated by Thioxanthone Derivatives: A Magnetic Field Effect (2009)

Free radical photopolymerization of methyl methacrylate (MMA) initiated by 2-mercaptothioxanthone (TX-SH), thioxanthone-thioacetic acid (TXSCH_2COOH), and thioxanthone-carboxymethoxy acetic acid (TXOCH_2COOH) as so called one-component initiators was performed with and without an external magnetic field (MF). These initiators contain light-absorbing and electron/hydrogen-donating fragments in one molecule and do not require an additional hydrogen donor, and initiate the polymerization of MMA in the air. Polymerization experiments were performed in solutions with 3 different optical densities at \lambda 365 nm, where the photoinitiator absorbs. It was observed that application of MF leads to both larger conversion and higher molecular weight of the prepared PMMA, other conditions being equal. The effect of MF on the photopolymerization of MMA is discussed.
Tritium pellet injector TPI-1 (2002)

Tasks and design of a tritium repeating pellet injector developed in Russia are presented. The injector uses improved in-situ and extrusion technologies for pellet formation.
Photocatalytic pretreatment of contaminated groundwater for biological nitrification enhancement (2002)

Abstract The sequential photocatalytic/biological treatment of a contaminated groundwater from a local industrial site was studied. The ground water contained approximately 100 mg dm −3 ammonia, as well as mg dm −3 levels of nitrification‐inhibiting organics such as chlorobenzene. An existing treatment system uses carbon adsorption pretreatment to remove the nitrification inhibitors before the water is treated in a biological nitrification system. Photocatalysis, using a corrugated plate photoreactor, was studied as an alternative to the carbon adsorption system for inhibitor removal. Photocatalytic pretreatment was found to significantly enhance the extent of biological nitrification. An optimal pretreatment time appeared to exist, since further pretreatment resulted in accumulation of nitrite. Although further study is required, there appears to be a potential for using photocatalysis to remove inhibitors from biological nitrification systems. © 2002 Society of Chemical Industry
An identified histaminergic neuron modulates feeding motor circuitry in Aplysia (1986)

An identified histaminergic neuron, C2, in the marine mollusk Aplysia is a complex mechanoafferent which appears to contribute to the maintenance of food arousal by means of its synaptic connections to the metacerebral cell (MCC). Because C2 also has extensive synaptic outputs to neurons other than the MCC, we studied its possible motor functions. We identified several synaptic followers of C2 and found that some were excitatory motor neurons for extrinsic muscles of the buccal mass, while others were modulatory motor neurons that inhibited contractions. In addition, we found that these neurons and other synaptic followers of C2 received powerful inputs during feeding motor programs. In order to determine the functional significance of the synaptic outputs of C2, we studied extrinsic buccal muscles (E4 and E5) whose motor neuron (C6) is excited by C2. Extracellular recordings from these muscles indicated that they receive input during swallowing and rejection, but not during biting movements. Lesions of these muscles, or of all extrinsic muscles, did not prevent animals from feeding, but decreased feeding efficiency, that is, the amount of seaweed an animal could ingest with each swallow. The data suggest that C2 is an integrative proprioceptive cell that functions as a premotor neuron. The non-MCC synaptic outputs of C2 may reinforce the actions of the central feeding motor program. Specifically, C2 appears to aid the functioning of muscles that produce fine adjustments of the buccal mass and contribute to the efficiency of feeding behavior, rather than in producing gross movements.
A rule-based method to model myocardial fiber orientation in cardiac biventricular geometries with outflow tracts (2018)

Rule-based methods are often used for assigning fiber orientation to cardiac\nanatomical models. However, existing methods have been developed using data\nmostly from the left ventricle. As a consequence, fiber information obtained\nfrom rule-based methods often does not match histological data in other areas\nof the heart such as the right ventricle, having a negative impact in cardiac\nsimulations beyond the left ventricle. In this work, we present a rule-based\nmethod where fiber orientation is separately modeled in each ventricle\nfollowing observations from histology. This allows to create detailed fiber\norientation in specific regions such as the endocardium of the right ventricle,\nthe interventricular septum and the outflow tracts. We also carried out\nelectrophysiological simulations involving these structures and with different\nfiber configurations. In particular, we built a modelling pipeline for creating\npatient-specific volumetric meshes of biventricular geometries, including the\noutflow tracts, and subsequently simulate the electrical wavefront propagation\nin outflow tract ventricular arrhythmias with different origins for the ectopic\nfocus. The resulting simulations with the proposed rule-based method showed a\nvery good agreement with clinical parameters such as the 10 ms isochrone ratio\nin a cohort of nine patients suffering from this type of arrhythmia. The\ndeveloped modelling pipeline confirms its potential for an in silico\nidentification of the site of origin in outflow tract ventricular arrhythmias\nbefore clinical intervention.\n
Role of Confocal Laser Endomicroscopy in Detection of Residual Barrett's Esophagus after Radiofrequency Ablation (2011)

Endoscopic endoluminal radiofrequency ablation (RFA) is a novel and promising modality for Barrett's esophagus (BE) treatment. Actually the only surveillance method after the ablation treatment is random biopsies throughout the whole treated area. Confocal laser endomicroscopy (CLE) is a new endoscopic imaging tool that permits high-resolution microscopic examination of the gastrointestinal tract. The technology has garnered increasing attention because of its ability to provide real-time "optical" biopsy specimens, with a very high sensitivity and specificity. This paper summarize the potential application of CLE in the surveillance of the reepithelialization of BE, after endoscopic RFA.
<title>Fiber optic sensor for adsorption studies using surface plasmon resonance</title> (1995)

An optical fiber sensor for absorption studies based on surface plasmon resonance (SPR) interrogation in the wavelength domain is proposed. The SPR wavelength is measured with high resolution which makes it possible to detect very small changes in SPR owing to the absorption of molecules onto the sensing surface. As a model case, the absorption of water molecules on silicon dioxide was studied experimentally.
Fatigue and Fracture of Medical Metallic Materials and Devices (2007)

Description Get the latest information on the thermal and mechanical properties of shape memory alloys (SMA's) and metallic medical materials and devices. Eleven peer-reviewed papers: • Define the environments in body-specific locations such as the superficial femoral artery, carotid, abdominal and thoracic arteries • Develop constitutive expressions for the deformation response of nitinol via specific test methodologies and data analyses • Develop the appropriate mechanics analyses for cumulative damage calculations and to ultimately • Ascertain the fatigue lifetime of medical devices in the human body. The principle focus of this new publication is on nitinol since these unique alloys offer the designer new dimensions in controlling the shape of devices used in medical and many structural applications. Shape memory devices such as valves, actuators, clutches, and gaskets are proposed for monitoring units, drive systems, and repair schemes. STP 1481 also covers other metallic medical materials and devices.
d-6. Dynamic Aspects of Glioma Cells <i>in vitro</i> (1968)

2-year-survival-rate was 29% and 3-year-survival-rate was 15%, and the longest survival period was 9 years after operation. Generally, the survival period of the astrocytoma grade 2 was much similar to that of the astrocytoma grade 3/4.
Second Generation of Freescoo Solar DEC Prototypes for Residential Applications (2015)

Freescoo is an innovative all-in-one compact solar Desiccant Evaporative Cooling (DEC) air conditioner concept. Results of the first prototype developed were presented at SHC Conference last year. Now a second generation of freescoo prototypes for applications in residential and small office buildings have been installed in Italy at ENEA Casaccia and at UNIPA. The thermodynamic cycle is based on the use of fixed and cooled adsorption beds and advanced evaporative cooling concepts. The adsorption bed, which is a fin and tube heat exchanger packed with silica gel grains, allows simultaneous dehumidification and cooling of the process air. The indirect evaporative cooling process, operated downstream to the dehumidification, is realized usingan optimized configuration with two wet plate heat exchangers connected in series. Low wet bulb temperatures reached on the secondary flow, allow supply air temperatures to the room below 20 °C. Systems are designed also for stand-alone operation thanks to a battery accumulator and PV cells installed. No auxiliary device is used for cold production. The main features of the second generation prototype system are first discussed, as well as some optimizations carried out from the first to the second generation prototype. Results are related both to field monitoring data. Performance indicators such EER and thermal COP, maximum cooling power achieved, stand alone operation data and control issues are presented and discussed.
Hands-on learning in biomedical signal processing (2003)

For 20 years, the Harvard-MIT Division of Health Sciences and Technology (HST) has offered a graduate-level course on Biomedical Signal and Image Processing (HST582J). This course takes a practical, hands-on approach to learning about signal processing and physiological signals through the application of digital signal processing methods to biomedical problems. It is by all accounts a successful course, with steadily increasing enrollment and high student satisfaction. In recent years, we have instituted a number of changes in the course, motivated by our awareness of new pedagogical strategies and assessment techniques. The purpose of this article is to use HST582J as a case study, demonstrating how incremental changes can improve an already successful course and ensure that hands-on exercises are not only fun and interesting but also achieve the desired learning objectives.
Asteroseismology of RXJ 2117+3412, the hottest pulsating PG 1159 star (2021)

The pulsating PG 1159 planetary nebula central star RXJ 2117+3412 has been observed over three successive seasons of a multisite photometric campaign. The asteroseismological analysis of the data, based on the 37 identified
Migratory Bee Hive Transportation Contributes Insignificantly to Transgenic Pollen Movement Between Spatially Isolated Alfalfa Seed Fields (2016)

Contracted commercial beekeeping operations provide an essential pollination service to many agricultural systems worldwide. Increased use of genetically engineered crops in agriculture has raised concerns over pollinator-mediated gene flow between transgenic and conventional agricultural varieties. This study evaluated whether contracted migratory beekeeping practices influence transgenic pollen flow among spatially isolated alfalfa fields. Twelve honey bee (Apis mellifera L.) colonies were permitted to forage on transgenic alfalfa blossoms for 1 wk in Touchet, WA. The hives were then transported 112 km to caged conventional alfalfa plots following one and two nights of isolation (8 and 32 h, respectively) from the transgenic source. Alfalfa seed harvested from the conventional plots was assessed for the presence of the transgene using a new seedling germination assay. We found that 8 h of isolation from a transgenic alfalfa source virtually eliminated the incidence of cross-pollination between the two varieties.
Three-dimensional high-resolution particle tracking for optical tweezers by forward scattered light (1999)

A quadrant photodiode placed in the back-focal plane of the microscope of a laser trap provides a high-resolution position sensor. We show that in addition to the lateral displacement of a trapped sphere, its axial position can be measured by the ratio of the intensity of scattered laser light to the total amount of the light reaching the detector. The addition of the axial information offers true three-dimensional position detection in solution, creating, together with a position control, a photonic force microscope with nanometer spatial and microsecond temporal resolution. The measured position signals are explained as interference of the unscattered trapping laser beam with the laser light scattered by the trapped bead. Our model explains experimental data for trapped particles in the Rayleigh regime (radius a <0.2lambda) for displacements up to the focal dimensions. The cross-talk between the signals in the three directions is explained and it is shown that this cross-talk can be neglected for lateral displacements smaller than 75 nm and axial displacements below 150 nm. The advantages of three-dimensional single-particle tracking over conventional video-tracking are shown through the example of the diffusion of the GPI-anchored membrane protein Thy1.1 on a neurite.
Oxygen thermochemical treatment combined with DLC coating for enhanced loadbearing capacity of Ti–6Al–4V (1998)

In the present investigation, a novel duplex treatment of Ti–6Al–4V combining oxygen diffusion (OD) treatment with a carbon rich coating has been developed. A diamond like carbon (DLC) coating containing a small amount of titanium was deposited on to 0D treated Ti–6Al–4V using an unbalanced magnetron sputtering system. A graded intermediate layer of Ti/TiN /TiCN /TiC between the 0 D treated zone and the DLC coating was applied to facilitate good bonding. The loadbearing capacities of the duplex treated, as well as solely DLC coated, Ti–6Al–4V specimens were evaluated, both statically and dynamically using a friction monitored scratch tester, a ball on disc tribometer, and an indentation tester. It was found that both the staticand dynamic loadbearing capacities were significantly increased by a factor of 2·5 to 5 following the twofold treatment. Based onfurther fractographic examinations by high resolution SEM and finite element analysis, the excellent performance of the duplex system is discussed in terms of plastic deformation of the substrate, interface maximum shear stress, and coating/substrate interfacial integrity.
Identification of a G-Protein coupled receptor for esterified 15(S)hydroxyeicosatetraenoic acid on human primary bronchial epithelial cells (P6255) (2013)

Abstract In asthmatic epithelium, the TH2 cytokine milieu results in production of phospholipid-esterified 15-HETE and elevated mucus secretion. A high-throughput 15-HETE binding assay was developed using 15-HETE esterified to biotin and Streptavidin-AlexaFluor488 to form the ligand (15HETE-Bt:SA-AlF). 15HETE-Bt:SA-AlF binding to Beas-2B cells and PBEC grown under air-liquid interface were assessed from 2- 60 min. Specificity of binding was monitored with unlabeled fatty acids [0.05-10 μM], biotin-hydrazide and SA-ALF. CyclicAMP (cAMP) was quantified using a competitive immunoassay kit. Intracellular calcium [Ca2+]i was measured (Fluo-3 / Fura-red) by flow cytometry. Beas-2B (n=8) and PBEC (n=3 donors) demonstrated time-dependent binding of 15HETE-Bt:SA-AlF, reaching equilibrium at 30 min., 4 deg.C. Binding of 15HETE-Bt:SA-AlF was dose-dependently displaced on Beas2B with 15-HETE&gt;12-HETE, 5-HETE &gt; 5,15diHETE,&gt;15-KETE &gt;&gt; LTB4 (p&lt; .05, 15-HETE vs. other fatty acids) whereas biotin-hydrazide:SA-ALF or SA-ALF were ineffective. In Beas2B cells, 15-HETE-Bt [0.1 - 10 μM] induced pM [cAMP] (n =4) whereas cholera toxin pretreatment (1 μg/ml, 5 hr.) inhibited 55-100% of cAMP production (n=2). A transient increase in [Ca2+]i was detected with 3-10 μM 15-HETE-Bt or 15-HETE in Beas2B (n=2). Bronchial epithelial cells exhibit specific, reversible binding of esterified 15-HETE suggesting a unique Gs- GPCR for esterified 15-HETE that may regulate airway inflammation in asthma.
MAJOR BREAKTHROUGH IN TUNABLE SOLID-STATE LASERS (1988)

Get PDF Email Share Share with Facebook Tweet This Post on reddit Share with LinkedIn Add to CiteULike Add to Mendeley Add to BibSonomy Get Citation Copy Citation Text V. PETRICEVIC, S. K. GAYEN, and R. R. ALFANO, "MAJOR BREAKTHROUGH IN TUNABLE SOLID-STATE LASERS," Optics News 14(12), 13-14 (1988) Export Citation BibTex Endnote (RIS) HTML Plain Text Citation alert Save article
Nanopatterning of GeTe phase change films via heated-probe lithography (2017)

The crystallization of amorphous germanium telluride (GeTe) thin films is controlled with nanoscale resolution using the heat from a thermal AFM probe. The dramatic differences between the amorphous and crystalline GeTe phases yield embedded nanoscale features with strong topographic, electronic, and optical contrast. The flexibility of scanning probe lithography enables the width and depth of the features, as well as the extent of their crystallization, to be controlled by varying probe temperature and write speed. Together, these technologies suggest a new approach to nanoelectronic and opto-electronic device fabrication.
Metal‐Organic Framework Materials (2010)

This chapter contains sections titled: Introduction Porosity Incorporation of Other Properties Concluding Remarks Acknowledgements References
Thermal poling of glass modified by femtosecond laser irradiation (2002)

Thermal poling of silica glass modified by femtosecond laser irradiation is demonstrated. Increase of second-harmonic generation in the irradiated regions is observed. This enhancement is interpreted in terms of structural modifications in silica glass that make the poling process more efficient. Evidence of a change in the distribution of the electrostatic field frozen in glass during poling is obtained. This technique is used for χ(2) grating fabrication.
Effect of anomalous resistivity on MHD wave damping (1995)

We investigate the effect of nonlinearity of the voltage current plasma characteristic on the damping rate of shear and compressional Alfvén waves in current‐carrying plasmas. It is shown that the shear Alfvén wave experiences much stronger turbulent damping than compressional wave due to its effect on the level of ion acoustic turbulence excited by an external current.
Assessment of antibodies to double‐stranded DNA induced in rheumatoid arthritis patients following treatment with infliximab, a monoclonal antibody to tumor necrosis factor α: Findings in open‐label and randomized placebo‐controlled trials (2000)

Objective To compare the incidence of anti–double-stranded DNA (anti-dsDNA) antibodies in rheumatoid arthritis (RA) patients receiving either single or multiple doses of a chimeric anti–tumor necrosis factor α (anti-TNFα) antibody or placebo infusions, with or without methotrexate, in open-label, randomized, placebo-controlled trials. Methods Multiple sera obtained from 156 patients before and after treatment with infliximab and from 37 patients treated with placebo infusions were tested for anti-dsDNA antibodies by 3 methods: Crithidia luciliae indirect immunofluorescence test (CLIFT), a commercial Farr assay (Ortho Diagnostics radioimmunoassay [RIA]) in which the antigen source is mammalian DNA, and a Farr assay employing 125I-labeled circular plasmid DNA (Central Laboratory of The Netherlands Red Cross Blood Transfusion Service [CLB] RIA). Patients with positive findings on the CLIFT were also tested for antibodies to histones (H1–H5) and chromatin and for IgM rheumatoid factors (IgM-RFs). Results None of the RA patients had a serum sample that was positive for anti-dsDNA antibodies by the CLIFT prior to infliximab therapy. Of the 22 patients who developed a positive CLIFT result, 11 (7% of 156 exposed to infliximab) also had positive findings on the Ortho RIA at a concentration of >10 units/ml and another 8 (5%) were positive at a concentration of >25 units/ml. In all but 1 patient, the anti-dsDNA antibodies were solely of the IgM isotype. Only 1 patient had detectable anti-dsDNA antibodies by the CLB RIA. All sera containing anti-dsDNA by the CLIFT contained antibodies to chromatin, and sera from 2 patients also contained antibodies to histones. IgM-RF titers showed a significant reduction following infliximab therapy in these 22 patients. One patient developed anti-dsDNA antibodies of IgG, IgA, and IgM isotype and had positive results on both Farr assays (peaking at 22 weeks and resolving by 54 weeks); this was associated with a reversible lupus syndrome. Conclusion Anti-dsDNA antibodies of IgM class are induced by infliximab therapy; the frequency is dependent on the assay method used. Only 1 of the 156 patients who were treated with infliximab developed a self-limiting clinical lupus syndrome; that patient developed high titers of anti-dsDNA antibodies of IgG, IgM, and IgA class, as detected by the CLIFT and by 2 different Farr assays.
Age-Specific Nonpersistence of Endocrine Therapy in Postmenopausal Patients Diagnosed with Hormone Receptor–Positive Breast Cancer: A TEAM Study Analysis (2011)

Nonpersistence within 1 year of follow-up was associated with lower breast cancer-specific and overall survival probabilities in patients aged <65 years, but it was not associated with survival outcomes in patients aged 65-74 years or in patients aged ≥75 years. These results suggest that extrapolation of outcomes from a young to an elderly breast cancer population may be insufficient and urge age-specific breast cancer studies.
Identification and characterization of the STIM (stromal interaction molecule) gene family: coding for a novel class of transmembrane proteins (2001)

STIM1 (where STIM is stromal interaction molecule) is a candidate tumour suppressor gene that maps to human chromosome 11p15.5, a region implicated in a variety of cancers, particularly embryonal rhabdomyosarcoma. STIM1 codes for a transmembrane phosphoprotein whose structure is unrelated to that of any other known proteins. The precise pathway by which STIM1 regulates cell growth is not known. In the present study we screened gene databases for STIM1-related sequences, and have identified and characterized cDNA sequences representing a single gene in humans and other vertebrates, which we have called STIM2. We identified a single STIM homologue in Drosophila melanogaster (D-Stim) and Caenorhabditis elegans, but no homologues in yeast. STIM1, STIM2 and D-Stim have a conserved genomic organization, indicating that the vertebrate family of two STIM genes most probably arose from a single ancestral gene. The three STIM proteins each contain a single SAM (sterile α-motif) domain and an unpaired EF hand within the highly conserved extracellular region, and have coiled-coil domains that are conserved in structure and position within the cytoplasmic region. However, the STIM proteins diverge significantly within the C-terminal half of the cytoplasmic domain. Differential levels of phosphorylation appear to account for two molecular mass isoforms (105 and 115kDa) of STIM2. We demonstrate by mutation analysis and protein sequencing that human STIM2 initiates translation exclusively from a non-AUG start site in vivo. STIM2 is expressed ubiquitously in cell lines, and co-precipitates with STIM1 from cell lysates. This association into oligomers in vivo indicates a possible functional interaction between STIM1 and STIM2. The structural similarities between STIM1, STIM2 and D-STIM suggest conserved biological functions.