gebhart/patrepeval huggingface dataset:
Regulatory T Cells in Kidney Allograft Infiltrates Correlate With Initial Inflammation and Graft Function (2010)

These data suggest Treg recruitment at the acute phase of the allogenic response, where they could act to diminish the interstitial inflammation and its associated lesions.
Deep Wide-Field<i>BVI</i>CCD Photometry of the Sextans Dwarf Spheroidal Galaxy (2003)

We present deep wide-field VI CCD photometry of the Sextans dwarf spheroidal galaxy (dSph) in the Local Group, covering a field of 42' × 28' located at the center of the galaxy (supplemented by short B photometry). The limiting magnitudes with 50% completeness are V = 24.4 mag and I = 23.6 mag. Color-magnitude diagrams of the Sextans dSph show a well-defined red giant branch (RGB), blue horizontal branch (BHB), prominent red horizontal branch (RHB), and asymptotic giant branch (AGB), as well as ∼120 variable star candidates including RR Lyrae stars and anomalous Cepheids, ∼230 blue stragglers (BSs), and main-sequence (MS) stars. The main-sequence turnoff (MSTO) of the old population is found to be located at V ≈ 23.7 mag and V-I ≈ 0.56. The distance to the galaxy is derived using the I-band magnitude of the tip of the RGB at ITRGB = 15.95 ± 0.04: (m - M)0 = 19.90 ± 0.06, for an adopted reddening of E(B-V) = 0.01. This estimate agrees well with the distance estimate based on the mean V-band magnitude of the HB at V(HB) = 20.37 ± 0.04. The mean metallicity of the RGB is estimated from the V-I color: [Fe/H] = -2.1 ± 0.1 (statistical error) ±0.2 (standard calibration error) dex, with a dispersion of σ[Fe/H] = 0.2 dex. The age of the MSTO of the main old population is estimated to be similar to that of the metal-poor Galactic globular cluster M92, and some stellar populations with younger age are seen. There is found to be one RGB bump at V = 19.95 ± 0.05 mag (MV = 0.03 mag) and a weak brighter bump at V = 19.35 ± 0.05 mag (MV = -0.58 mag), which is probably an AGB bump. The V-band luminosity function of the RGB and MS stars is in general similar to that of the globular cluster M92, with a slight excess of stars in the magnitude range brighter than the MSTO with respect to that of M92. The bright BSs are more centrally concentrated than the faint BSs. The V-band luminosity function of the BSs in the inner region is found to extend to a brighter magnitude and to have a flatter slope compared with that of the BSs in the outer region. Significant radial gradients are seen for several kinds of populations: the RHB, the red RGB, the red subgiant branch (SGB), and the bright BSs are more centrally concentrated toward the center of the galaxy compared with the BHB, the blue RGB, the blue SGB, and the faint BSs, respectively.
Full‐waveform model and measurements of electromagnetic to seismic conversion (2011)

The development of electromagnetic to seismic conversion (electroseismic) exploration methods is hindered by a scarcity of investigations. Here we present a full‐waveform electroseismic model that predicts the conversion of electromagnetic waves to acoustic waves at a fluid/porousmedium interface. The conversion is on the order of 10 Pa for a 1 C/m2s line source of vertical electric current. Laboratory measurements of electroseismic conversions are shown for a synthetic porous sample and a natural rock. The results allow the appreciation of electroseismic exploration methods.
Synergistic toughening of composite fibres by self-alignment of reduced graphene oxide and carbon nanotubes (2012)

The extraordinary properties of graphene and carbon nanotubes motivate the development of methods for their use in producing continuous, strong, tough fibres. Previous work has shown that the toughness of the carbon nanotube-reinforced polymer fibres exceeds that of previously known materials. Here we show that further increased toughness results from combining carbon nanotubes and reduced graphene oxide flakes in solution-spun polymer fibres. The gravimetric toughness approaches 1,000 J g(-1), far exceeding spider dragline silk (165 J g(-1)) and Kevlar (78 J g(-1)). This toughness enhancement is consistent with the observed formation of an interconnected network of partially aligned reduced graphene oxide flakes and carbon nanotubes during solution spinning, which act to deflect cracks and allow energy-consuming polymer deformation. Toughness is sensitive to the volume ratio of the reduced graphene oxide flakes to the carbon nanotubes in the spinning solution and the degree of graphene oxidation. The hybrid fibres were sewable and weavable, and could be shaped into high-modulus helical springs.
HELIC-II: As a legal argumentation support system (2002)

Summary form only given. The authors present HELIC-II, a legal reasoning system on the parallel inference machine. HELIC-II draws legal conclusions for a given case by referring to a statutory law (legal rules) and judicial precedents (old cases). This system consists of two inference engines. The rule-based engine draws legal consequences logically by using legal rules. The case-based engine generates legal concepts by referencing similar old cases. These engines together draw all possible conclusions, and output them in the form of inference trees. Using these inference trees HELIC-II can support arguments in a legal suit. HELIC-II can draw conclusions quickly by parallel inference.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Kinetics of Alkanethiol Adsorption on Gold (1996)

ADVERTISEMENT RETURN TO ISSUEPREVNoteNEXTKinetics of Alkanethiol Adsorption on GoldW. Pan, C. J. Durning, and N. J. TurroView Author Information Department of Chemistry and Department of Chemical Engineering, Materials Science and Mining, Columbia University, New York, New York 10027Cite this: Langmuir 1996, 12, 18, 4469–4473Publication Date (Web):September 4, 1996Publication History Received2 November 1994Revised26 April 1996Published online4 September 1996Published inissue 1 January 1996https://pubs.acs.org/doi/10.1021/la9408634https://doi.org/10.1021/la9408634brief-reportACS PublicationsCopyright © 1996 American Chemical SocietyRequest reuse permissionsArticle Views1284Altmetric-Citations134LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Adsorption,Alcohols,Crystals,Ethanol,Gold Get e-Alerts
Oxygenated fatty acids of oil from sunflower seeds after prolonged storage (1968)

Chemical analysis of a number of sunflower (Helianthus annuus) seed oil samples revealed a low and variable percentage of hydrogen bromide-reactive material. To characterize the compounds responsible for this reactivity, oil was extracted from selected introductions from Uruguay, Turkey, and Yugoslavia that had been subjected to prolonged storage. Two epoxy fatty acids and two conjugated dienolic acids were isolated from the methyl esters derived from these sunflower seed oils by using a combination of column chromatography and countercurrent distribution. The epoxy acids arecis-9,10-epoxystearic acid (0.5%) andcis-9,10-epoxy-cis-12-octadecenoic (coronaric) acid (2.2%). Characterization of the dienols revealed that they are 9-hydroxy-trans-10,cis-12-octadecadienoic acid (1.2%) and 13-hydroxy-cis-9,trans-11-octadecadienoic acid (1.3%). Fresher seed of some of these introductions contained less of the oxygenated components.Oil from recently produced seed of selected high-oil Russian sunflower varieties, including some currently grown in the United States, contained no more than trace amounts of oxygenated acids. Though the relative contributions of genetic and environmental factors toward genesis of oxygenated acids are not established, increase of those acids in some sunflower lines as a result of storage has been demonstrated.
Evaluation of Seebeck coefficients in n- and p-type silicon nanowires fabricated by complementary metal–oxide–semiconductor technology (2012)

Silicon-based thermoelectric nanowires were fabricated by using complementary metal-oxide-semiconductor (CMOS) technology. 50 nm width n- and p-type silicon nanowires (SiNWs) were manufactured using a conventional photolithography method on 8 inch silicon wafer. For the evaluation of the Seebeck coefficients of the silicon nanowires, heater and temperature sensor embedded test patterns were fabricated. Moreover, for the elimination of electrical and thermal contact resistance issues, the SiNWs, heater and temperature sensors were fabricated monolithically using a CMOS process. For validation of the temperature measurement by an electrical method, scanning thermal microscopy analysis was carried out. The highest Seebeck coefficients were - 169.97 μV K(-1) and 152.82 μV K(-1) and the highest power factors were 2.77 mW m(-1) K(-2) and 0.65 mW m(-1) K(-2) for n- and p-type SiNWs, respectively, in the temperature range from 200 to 300 K. The larger power factor value for n-type SiNW was due to the higher electrical conductivity. The total Seebeck coefficient and total power factor for the n- and p-leg unit device were 157.66 μV K(-1) and 9.30 mW m(-1) K(-2) at 300 K, respectively.
Influence of percutaneous mitral valve repair using the <scp>M</scp>itra<scp>C</scp>lip® system on renal function in patients with severe mitral regurgitation (2014)

Successful PMVR was associated with an improvement in renal function. The improvement in renal function was associated with the extent of MR reduction and pre-existing kidney dysfunction. Our data emphasize the relevance of PVMR to stabilize the cardiorenal axis in patients with severe MR.
New Androgen-Stimulated Proteins in the Kidneys of Female Mice* (1980)

Testosterone administration to female mice for 25 days produced a 70% increase in total kidney protein in both A/J and C57BL/6J mice. This is in contrast to the known androgen-responsive proteins, such as beta-glucuronidase and alcohol dehydrogenase, which each represent less than 1% of the total kidney proteins even after maximum stimulation. To investigate this discrepancy, we initiated a study to identify major proteins which increase with androgen treatment. Three new cytoplasmic proteins designated T1, T2, and T3 were found in different subcellular fractions of both A/J and C57BL/6J mice. T1 (43,000 daltons) and T2 (60,000 daltons) were found in the mitochondrial-lysosomal fraction of 25-day androgen-treated mice. T3 (54,000 daltons) was found in the microsomal fraction. Each of these proteins increased several-fold during androgen treatment, so that they were easily identified using sodium dodecyl sulfate polyacrylamide gel electrophoresis. By contrast, no major changes were noted in the soluble proteins. A nonhistone chromosomal protein of 54,000 mol wt (T4) was found in chromatin preparations from androgen-stimulated A/J mice. Additional studies with androgen-insensitive Tfm/Y mice and with various hormones indicated that stimulation of the T proteins was dependent on androgenic steroid and a functional androgen receptor.
Immunohistochemical Localization of Nuclear 3,5,3'-Triiodothyronine Receptor Proteins in Rat Tissues Studied with Antiserum against C-ERB A/T<sub>3</sub>Receptor* (1990)

We have previously raised an anti-c-erb A peptide antibody (designated 4B II) which immunoprecipitated in vitro transcription/translation products of c-erb A alpha 1 and beta. 4B II could recognize nuclear T3 receptor (NT3R) without distinction between difference in species and tissues. Using 4B II, we studied immunohistochemical localization of NT3R proteins in various tissues of the rat. Cryostat sections (4-6 microns) of selected rat tissues were incubated with 4B II at 4C overnight, followed by fluorescein-isothyocianate-conjugated anti-rabbit immunoglobulin G for 60 min at 25 C. The cellular localization of fluorescence in all tissues examined was exclusively nuclear. Under the same conditions, control sections stained with antiserum which had previously absorbed with c-erb A peptide or inactive serum showed no specific staining. In the brain the large nuclei, supposed to be neuronal, were strongly stained in the cerebral cortex and the granular layer of the cerebellum. In the kidney, cells in the glomerulus, the distal, but not the proximal, tubules, and the collecting ducts exhibited nuclear staining. Nuclear fluorescence was observed homogeneously in the heart and liver, but the intensity was much weaker in the latter. Less intense fluorescence was seen in the testis and spleen, although specific immunostaining was clearly observed in the nuclei of spermatocytes, Leydig cells, and the heads of the sperms in the testis, and many lymphocytes in the spleen. Nuclei of follicular cells of the thyroid exhibited very strong fluorescence, suggesting existence of plenty of NT3R proteins. The anterior pituitary showed strong immunostaining in most nuclei, and clear nuclear fluorescence was also detected in the intermediate lobe of the pituitary. The present study showed that NT3R distributes selectively in certain types of cells in many tissues and that the content of NT3R proteins seems to correlate with the concentration of c-erb A mRNA alpha 1 and beta among many organs.
Mucociliary transport determined by in vivo microdialysis in the airways of normal and CF mice (2004)

We report a novel method to measure mucociliary transport (MCT) in both the upper and lower airways of normal and CF mice. The in vivo microdialysis technique involves placing a small quantity of dye on the airway surface and a microdialysis probe a defined distance from the site of dye deposition. The dye is transported toward the probe by ciliary transport and, upon reaching the microdialysis probe, diffuses across the dialysis membrane and is collected in the dialysate leaving the probe. The rate of MCT is calculated from the length of time from dye deposition to recovery. The rate of tracheal MCT in normal mice was 2.2 +/- 0.45 (SE) mm/min (n = 6), a value similar to that in reports using other techniques. MCT in CF mice was not different (2.3 +/- 0.29, n = 6), consistent with previous observations suggesting that tracheal ion transport properties are not different between CF and normal mice. The rate of MCT in the nasal cavity of normal mice was slower than in the trachea (1.3 +/- 0.26, n = 4). MCT in the CF mouse nasal cavity (1.4 +/- 0.31, n = 8), a region in which the CF mouse exhibits bioelectric properties similar to the human CF patient, was, again, not different from the normal mouse, perhaps reflecting copious gland secretion offsetting Na(+) and liquid hyperabsorption. In conclusion, we have developed a versatile, simple in vivo method to measure MCT in both upper and lower airways of mice and larger animals.
Salinity-dependent copy number increase of a marine cyanobacterial endogenous plasmid (1991)

A marine cyanobacterium Synechococcus sp. NKBG 042902 grown in the presence of various NaCl concentrations showed different plasmid profiles. This strain possesses a 2.7-kb endogenous plasmid pSY10, whose copy number increased five-fold when the salinity of the growth medium was increased from 0 to 3% NaCl. Cells were grown initially in a fresh water medium and then transferred to a NaCl supplemented medium. The copy number of pSY10 began to increase after 7 h of incubation in 3% NaCl BG11 medium. This phenomenon was specific to NaCl and did not occur when other osmotica such as KCl and sorbitol were used. This is the first report of a cyanobacterial plasmid with a salinity-dependent copy number.
Characterization of the Heparin-Mediated Activation of PKR, the Interferon-Inducible RNA-Dependent Protein Kinase (1996)

Heparin can substitute for double-stranded (ds) RNA in the autophosphorylation and activation of the interferon-inducible, RNA-dependent elF-2 alpha protein kinase (PKR). We have used heparin oligosaccharides of defined lengths to examine the heparin-mediated activation of human PKR. Heparin oligosaccharide with 8 sugar residues was nearly as efficient as 16-residue heparin (Hep-16) in mediating the activation of PKR autophosphorylation, whereas 6-residue heparin was a poor activator. When examined in combination, Hep-16 and dsRNA did not act synergistically in activating PKR autophosphorylation. The RNA-binding activity of recombinant PKR, measured with adenovirus VA RNA, was competed by poly(rl):poly(rC) but not by Hep-16. When the catalytically inactive, histidine-tagged mutant PKR protein [His-PKR(K296R)] was examined as a substrate for purified wild-type PKR, the intermolecular phosphorylation of His-PKR(K296R) was efficiently catalyzed by dsRNA-activated PKR but not by heparin-activated PKR. However, elF-2 alpha phosphorylation was catalyzed by both heparin-and dsRNA-activated PKR. Preincubation of PKR with Hep-16 in the absence of ATP blocked subsequent autophosphorylation mediated either by Hep-16 or dsRNA, whereas preincubation with dsRNA either alone or in combination with Hep-16 did not impair subsequent autophosphorylation. Neither Hep-16 nor dsRNA caused a detectable degradation of PKR during preincubation or subsequent autophosphorylation of PKR. These results suggest that, while both dsRNA and heparin are capable of activating PKR autophosphorylation, the structural and functional basis of PKR activation differs for these two classes of polyanionic biomolecules.
Effect of Indion Complexation on the Stability and Bioavailability of some Non-steroidal Anti-inflammatory Drugs (2012)

Ion exchange resins are commonly used for masking of drug objectionable taste. Our work aimed to study the effect of this complexation on the drug stability and bioavailability in rabbits. In this work, paracetamol and ibuprofen complexes with indion 204 were prepared; drug stability and bioavailability from the prepared complexes were studied and compared with that of the commonly used commercial tablets Tylenol and Motrin respectively. The clinical protocol and information about drugs were discussed with a group of healthy albino rabbits. The results showed that t max of both drugs were kept constant at 1.5hrs and 2hrs without any change from the reference standards Tylenol and Motrin respectively. The calculated pharmacokinetic parameters Cp max, AUC (0-24) and AUC (0- ∞ ) respectively for paracetamol were 0.431µg/ml, 3.535µg.hr/ml and 3.756µg.hr/ml from the prepared complexes in comparison to 0.494µg/ml, 4.083µg.hr/ml, 4.198µg.hr/ml from Tylenol, and 0.743µg/ml, 5.380µg.hr/ml, 5.559µg.hr/ml from the prepared ibuprofen complexes in comparison to 0.803µg/ml, 6.272 µg.hr/ml, 6.432 µg.hr/ml from Motrin. The relative bioavailability of both drugs from the prepared complexes were calculated using Tylenol and Motrin as reference standards and the 90 % confidence intervals of the geometric mean values for the test/reference ratios for Cp max, AUC (0-24) and AUC (0- ∞ ) were within the bioequivalence acceptance range of 80–125 % according to the European Guideline. Statistical analysis (ANOVA) indicated a significance difference between the calculated pharmacokinetic parameters for both drugs. From these results we can conclude that indion complexation of drugs significantly affects their pharmacokinetics and retards their bioavailability.
Telecommunications Primer: Data, Voice and Video Communications, 2ndEdition (2002)

Get PDF Email Share Share with Facebook Tweet This Post on reddit Share with LinkedIn Add to CiteULike Add to Mendeley Add to BibSonomy Get Citation Copy Citation Text Bogdan Hoanca, "Telecommunications Primer: Data, Voice and Video Communications, 2nd Edition," J. Opt. Netw. 1, 112-113 (2002) Export Citation BibTex Endnote (RIS) HTML Plain Text Citation alert Save article
Persistence-based segmentation of deformable shapes (2010)

In this paper, we combine two ideas: persistence-based clustering and the Heat Kernel Signature (HKS) function to obtain a multi-scale isometry invariant mesh segmentation algorithm. The key advantages of this approach is that it is tunable through a few intuitive parameters and is stable under near-isometric deformations. Indeed the method comes with feedback on the stability of the number of segments in the form of a persistence diagram. There are also spatial guarantees on part of the segments. Finally, we present an extension to the method which first detects regions which are inherently unstable and segments them separately. Both approaches are reasonably scalable and come with strong guarantees. We show numerous examples and a comparison with the segmentation benchmark and the curvature function.
The Subcellular Localization of the Long-Acting Thyroid Stimulator Inhibitor in Bovine Thyroid Gland* (1978)

To characterize further the nature and site of the receptor for the IgG stimulator in Graves' disease, we have developed a preparative scheme to provide a bovine thyroid subfraction rich in plasma membranes. Pellets (800 X g) obtained from bovine thyroid homogenates were layered on a 30-64% continuous sucrose gradient (SG). The centrifuged gradient was divided into four portions (SG1, 2, 3, and 4); and these along with the 800 X g pellet were characterized in terms of their capacity to neutralize (bind) the biological activity of LATS, their specific binding of [125I]TSH, and their subcellular marker content. Subfraction SG1 contained the highest adenyl cyclase specific activity, the highest [125I]TSH binding specific activity, and vied with the 800 X g pellet and SG3 for the highest specific activity of LATS neutralization. Electron microscopy of SG1 showed a predominance of plasma membrane structures contaminated with a modest amount of cellular debris. Adenyl cyclase activity in SG1 was enhanced by TSH, LATS, and sodium fluoride. Although a dose-response curve could be established for TSH, a similar relationship could not be established for LATS. We conclude that activation of plasma membrane-bound adenyl cyclase is associated with neutralization of the biological activity of LATS. Further, the difference between [125I]TSH binding and LATS neutralization activity observed in the various thyroid membrane subfractions suggests that either LATS and TSH interact at different sites or have different mechanisms of binding at a common site.
Bayesian Models for Multimodal Perception of 3D Structure and Motion (2008)

In this text we will formalise a novel solution, the Bayesian Volumetric Map (BVM), as a framework for a metric, short-term, egocentric spatial memory for multimodal perception of 3D structure and motion. This solution will enable the implementation of top-down mechanisms of attention guidance of perception towards areas of high entropy/uncertainty, so as to promote active exploration of the environment by the robotic perceptual system. In the process, we will to try address the inherent challenges of visual, auditory and vestibular sensor fusion through the BVM. In fact, it is our belief that perceptual systems are unable to yield truly useful descriptions of their environment without resorting to a temporal series of sensory fusion processed on a short-term memory such as the BVM.