gebhart/patrepeval huggingface dataset:
Dual-energy X-ray absorptiometry predicts bone formation in lower limb callotasis lengthening. (1997)

The rate of regenerate bone mineral content (BMC) acceleration was studied using dual-energy X-ray absorptiometry (DEXA) in callotasis lengthening of the lower limb. Eleven youngsters (age range 5-17 years) undergoing callotasis lengthening for congenital, post-traumatic or post-infective conditions were studied longitudinally. Patients were initially scanned once a week until completion of the lengthening phase, and at 2-week intervals thereafter until removal of the fixator. They were subsequently followed up at regular intervals on an outpatient basis for up to 2 years after removal of the fixator (average, 14 months). The BMC accretion slopes exhibited by the patients and the rate of new bone formation allowed the identification of three groups. In the fast formation group, the rate of new bone formation was 0.3-0.6% per day. In the moderate formation group the rate of new bone formation is 0.1-0.3% per day, while in the poor formation group the rate of new bone formation is < 0.1% per day. From the analysis of time graphs, a direct correlation emerged between early bone formation and subsequent bone mineral content accretion. Measurement of BMC during callotasis lengthening in the lower limb allows precise monitoring of the process. It may prove useful to prevent complications occurring after removal of the fixator at an unduly early stage, such as plastic deformation and fracture through the regenerate bone. It may be used to predict the bone formation rate in a given patient, and to implement measures to try to influence it.
Posttraumatic Immune Modulation in Chronic Alcoholics Is Associated with Multiple Organ Dysfunction Syndrome (2002)

The significantly elevated levels of IL-6, IL-10, and sE-selectin in chronic alcoholic trauma patients on admission to the ICU could play an important role in the development of MODS in intensive care. In patients with high levels of inflammatory mediators, immune modulatory treatment before the development of MODS may be considered.
Septic Arthritis, the Unexpected Complication (1969)

AbstractFourteen patients with septic arthritis superimposed on a variety of conditions have been reported. Physical examination of joints produces diagnostic suspicion, and joint paracentesis produces diagnostic certainty. In rheumatoid arthritis and other nonmalignant conditions, prompt diagnosis and proper therapy usually lead to complete recovery with preservation of joint function.
Microbial Hydrogen Production with Immobilized Sewage Sludge (2002)

Municipal sewage sludge was immobilized to produce hydrogen gas under anaerobic conditions. Cell immobilization was essentially achieved by gel entrapment approaches, which were physically or chemically modified by addition of activated carbon (AC), polyurethane (PU), and acrylic latex plus silicone (ALSC). The performance of hydrogen fermentation with a variety of immobilized-cell systems was assessed to identify the optimal type of immobilized cells for practical uses. With sucrose as the limiting carbon source, hydrogen production was more efficient with the immobilized-cell system than with the suspended-cell system, and in both cases the predominant soluble metabolites were butyric acid and acetic acid. Addition of activated carbon into alginate gel (denoted as CA/AC cells) enhanced the hydrogen production rate (v(H2)) and substrate-based yield (Y((H2)/sucrose)) by 70% and 52%, respectively, over the conventional alginate-immobilized cells. Further supplementation of polyurethane or acrylic latex/silicone increased the mechanical strength and operation stability of the immobilized cells but caused a decrease in the hydrogen production rate. Kinetic studies show that the dependence of specific hydrogen production rates on the concentration of limiting substrate (sucrose) can be described by Michaelis-Menten model with good agreement. The kinetic analysis suggests that CA/AC cells may contain higher concentration of active biocatalysts for hydrogen production, while PU and ALSC cells had better affinity to the substrate. Acclimation of the immobilized cells led to a remarkable enhancement in v(H2) with a 25-fold increase for CA/AC and ca. 10- to 15-fold increases for PU and ALSC cells. However, the ALSC cells were found to have better durability than PU and CA/AC cells as they allowed stable hydrogen production for over 24 repeated runs.
Ocular toxocariasis in a 36-year-old patient: a case report. (1995)

A 36-year-old female presented wit unilateral papillitis, followed by the development of a posterior pole granuloma. A positive ELISA-test for toxocara canis with a titer of 1/200 established the diagnosis. The patient was consecutively treated by pars plana vitrectomy and oral corticosteroids.
ChemInform Abstract: HERST. VON ADAMANTAN‐D16 (1971)

Abstract Aus dem Tricyclodecan (I) erhält man bei der Behandlung mit Deuterium in Gegenwart von Pd/Cdas deuterierte Derivat (II), das mit Aluminiumchlorid zum voll deuterierten Adamantan (III) umgelagert wird.
A Synthesis of<i>dl</i>-C<sub>17</sub>-<i>Cecropia</i>Juvenile Hormone (1972)

A novel synthesis of dl-C17-Cecropia juvenile hormone (I) was accomplished.
A wavelet based method for the extraction of sea wave orientation (2005)

In this paper, a method for determining sea wave orientation from image data is presented. Instead of focusing on images that cover vast distances such as those obtained from satellite synthetic aperture radar (SAR), this research is concerned with images acquired on a local level such as those obtained from a ship based, mast mounted camera. The developed method is based on the two-dimensional wavelet transform and its ability to isolate (or preserve) directional features contained in the root image. Another important property associated with wavelets is the notion of scale or resolution. The dominant wave features of the image are extracted through the use of a multi-scale wavelet analysis. These features are then used to determine the overall wave orientation for the image. Results are shown for images taken from both traditional visual cameras and forward-looking infrared (FLIR) based cameras.
Inorganic coordination polymers. XIV. Chromium(III) phosphinate perfluorocarboxylate polymers (1974)

Abstract A series of polymers, {Cr(OH)(OPRR′O)[OOC(CF 2 ) n CF(CF 3 ) 2 ]} x has been prepared and studied. The polymers with R = R′ = C 6 H 5 are soluble in CCl 2 FCClF 2 , whereas those with R = CH 3 and R′ = C 6 H 5 and with R = R′ = C 8 H 17 are insoluble in all solvents. Attempts to prepare similar materials without hydroxyl groups gave the polymers {Cr(OH) r (OPRR′O) p [OOC(CF 2 ) n CF(CF 3 ) 2 ] q } x with 0 < r < 1. The latter polymers are much more tractable than the former; however they are also less thermally stable. The perfluoro‐carboxylate groups in these materials can either be chelating or bridging, depending on the other ligands present.
Claiming More: The Increased Voluminosity of Patent Applications and its Determinants (2006)

The joint increase in the number and size of patents filed around the world puts the patent system under pressure. This paper analyses the sources of this surge in number of claims and pages of patent applications at the EPO. Four hypotheses are scrutinized: the diffusion of national drafting practices, the increasing complexity of inventions, the emergence of new sectors, and new patenting strategies. The results show that the increasing voluminosity is explained by all these hypotheses and suggest that the diffusion of the US model through the PCT is one of the major factors driving the size of EPO patent applications.
Backscatter from the ocean surface at low frequency (1982)

Backscatter strengths from the ocean surface were measured using a vertically directive, impulsive sound source having a 26-Hz bandwidth centered at a frequency of 52 Hz. The ocean surface was characterized by a 6.3-m swell having an 80-m wavelength, with 15-kt wind waves superposed. Backscatter strengths were measured as functions of the vertical grazing angle θ and of the horizontal angle ψ between the swell and the backscatter directions. The results are summarized by the expression for scattering strength, SS = −66.5 + 53 sin θ + 8.7 cos ψ. These values of scattering strength are somewhat larger than those reported by Brown and Saenger [M. V. Brown and R. A. Saenger, J. Acoust. Soc. Am. 52, 944–960 (1973)], but their data were not obtained from surfaces having such a large swell. The backscattered intensities have swell-induced amplitude modulation, suggesting that backscatter from wind waves is periodically shadowed by swell troughs. [Work supported by DARPA.]
Matched-field processing of multi-tone acoustic signals in shallow water with a horizontal line array (1997)

Matched-field processing results are presented which compare the resolution (in range, depth, and azimuth) and peak-to-sidelobe ratios obtained using a bottom-mounted horizontal line array and a tilted vertical line array. The arrays were deployed in the May 1996 shallow water evaluation cell experiment (SWellEx-96) carried out west of Point Loma in 200-m water of complex bathymetry. Results are presented for a towed source transmitting signals between 49 and 388 Hz at ranges between 0.7 and 6 km and at bearings between broadside and endfire. [Work sponsored by Office of Naval Research, Code 321(US).]
Fuel-Binder Requirement for Composite Propellants (1956)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTFuel-Binder Requirement for Composite PropellantsWilliam F. ArendaleCite this: Ind. Eng. Chem. 1956, 48, 4, 725–726Publication Date (Print):April 1, 1956Publication History Published online1 May 2002Published inissue 1 April 1956https://pubs.acs.org/doi/10.1021/ie50556a019https://doi.org/10.1021/ie50556a019research-articleACS PublicationsRequest reuse permissionsArticle Views103Altmetric-Citations2LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Turbojet and turbofan cycle considerations and engine configurations for application in lightweight aircraft (1968)

Cycle characteristics and structural configuration of turbojet and turbofan engines for lightweight aircraft
Personality and substance use in Japanese adolescents: The Japanese version of Substance Use Risk Profile Scale (2014)

Substance Use Risk Profile Scale (SURPS; Conrod & Woicik, 2002) measures four risk personality dimensions related to substance use; anxiety sensitivity (AS), hopelessness (H), sensation seeking (SS), impulsivity (IMP). The aim of this study is to develop the Japanese version of Substance Use Risk Profile Scale (SURPS-J) and to probe the reliability and validity of this scale to the Japanese context. This study consists of the test of the factor analysis (Study 1; N = 462), the reliability (Study 2; N = 64), and the validity (Study 3; N = 182). Our findings are as below; Study 1 showed the conformed factorial structure of SURPS-J and Study 2 revealed the good test–retest reliability. Additionally, Study 3 demonstrated the adequate validity of SURPS-J and its sensitivity in identifying risky drinking motivations and lifetime tobacco and alcohol use. Results showed that high H individuals are likely to experience smoking under the personal and collective situations, while high SS and IMP individuals are prone to drink alcohol under the collective situation. Additionally, high AS individuals are prone to drink by virtue of negative reinforcement motives and high SS and IMP drink by reason of all drinking reinforcement motives.
Kinetics of fibrinogen and platelet adherence to biomaterials. (1976)

The initial task was to establish a conceptually and materially simple test procedure that could quantitate and evaluate the thrombogenic potential of a biomaterial surface. Since the primary events of thrombus formation on prosthetic surfaces are believed to involve the deposition of a plasma protein monolayer followed by platelet adhesion to its fibrinogen component, it seemed reasonable to focus on the binding kinetics of fibrinogen and platelets to a commonly used biomaterial. Employing solutions of 125I-fibrinogen in buffered saline, the adsorption characteristics of several types of biomedical tubing could be compared, and the competition and exchange among plasma proteins at surface binding sites of PVC were evaluated. Human platelets with 51Cr were found to adhere to PVC surfaces proportional to surface fibrinogen concentration, but only in the presence of plasma; the circulation of labelled platelets in buffered saline only resulted in significant adherence to the native surface, while surface fibrinogen was inhibitory. Physiological concentrations of albumin were the most effective in preventing both fibrinogen adsorption and platelet adherence. The most important consequence of this work, perhaps, is the many avenues of future experimentation discovered from this methodological approach, not only in the thrombogenic evaluation of a specific biomedical surface, but also in the delineation of thrombogenic sequelae in general.
Microbial Sulfur Cycle in Two Hydrothermal Chimneys on the Southwest Indian Ridge (2014)

There have been limited studies on chimney sulfides located at ultraslow-spreading ridges. The analysis of metagenomes of hydrothermal chimneys on the ultraslow-spreading Southwest Indian Ridge suggests the presence of a microbial sulfur cycle. The sulfur cycle should be centralized within a microbial community that displays enrichment for sulfur metabolism-related genes. The present study elucidated a significant role of the microbial sulfur cycle in sustaining an entire microbial community in low-temperature hydrothermal chimneys on an ultraslow spreading midocean ridge, which has characteristics distinct from those of other types of hydrothermal fields.
A mutation in the glutamate-rich region of RNA-binding motif protein 20 causes dilated cardiomyopathy through missplicing of titin and impaired Frank–Starling mechanism (2016)

A mutation outside the mutational hotspot of RBM20 results in haploinsufficiency of RBM20. This leads to disturbed alternative splicing of TTN, resulting in a dramatic shift to highly compliant titin isoforms and an impaired FSM. These effects may contribute to the early onset, and malignant course of DCM caused by RBM20 mutations. Altogether, our results demonstrate that heterozygous loss of RBM20 suffices to profoundly impair myocyte biomechanics by its disturbance of TTN splicing.
Response of Beta Cells to Different Levels of Glucose: Fetal Pancreases Grown in Organ Culture and Subsequently Transplanted to Maternal Hosts (1970)

Portions of pancreases from fetal rats (normal or alloxan diabetic mothers) of 19.5 days were grown in organ culture for four days on either a low glucose medium (162 to 170 mg. glucose per 100 ml.) or a high glucose medium (1,031 to 1,073 mg. glucose per 100 ml.). Certain cultures were fixed for microscopic study. Other cultures were transplanted to the mothers at two sites: into the anterior chamber of the eye and under the capsule of the kidney. Four or ten days later, the grafts were removed, fixed and prepared for microscopic study. Pancreases of fetuses from normal mothers had granulated beta cells at the time of explantation. When explants were grown on the high glucose medium, the beta cells became degranulated—the insulin stored at the time of explant was released from the beta cells. Subsequent transplantation of such cultures into the normal mothers restored the beta cell granulation, i.e., new insulin was synthesized and stored within the beta cells. Pancreases of fetuses from alloxanized diabetic mothers had de granulated beta cells at the time of explantation. When these explants were grown on the low glucose medium, the beta cells developed extensive granulation representing a synthesis and storage of insulin. Following subsequent transplantation of such cultures into the diabetic mothers, the beta cells became degranulated, i.e., release of stored insulin from the beta cells. These observations indicate that the beta cells maintain their functional integrity (ability to store or release insulin in response to glucose) both in organ culture and when subsequently grown as grafts in maternal hosts.
The English turf : a record of horses and courses / by Charles Richardson ; edited by E. T. Sachs ... (1901)

An exhaustive account of the principal races of the nine- teenth century would alone involve a series of volumes longer than any encyclopaedia yet published, and as this volume deals with the Turf as it is, j ust enough reference to the past, and no more, is made to enable some sort of comparison to be made between the horses of the present and of former generations.
Dihydroceramide-based Response to Hypoxia (2011)

To understand the mechanisms of ceramide-based responses to hypoxia, we performed a mass spectrometry-based survey of ceramide species elicited by a wide range of hypoxic conditions (0.2-5% oxygen). We describe a rapid, time-dependent, marked up-regulation of dihydroceramides (DHCs) in mammalian cells and in the lungs of hypoxic rats. The increase affected all DHC species and was proportional with the depth and duration of hypoxia, ranging from 2- (1 h) to 10-fold (24 h), with complete return to normal after 1 h of reoxygenation at the expense of increased ceramides. We demonstrate that a DHC-based response to hypoxia occurs in a hypoxia-inducible factor-independent fashion and is catalyzed by the DHC desaturase (DEGS) in the de novo ceramide pathway. Both the impact of hypoxia on DHC molecular species and its inhibitory effect on cell proliferation were reproduced by knockdown of DEGS1 or DEGS2 by siRNA during normoxia. Conversely, overexpression of DEGS1 or DEGS2 attenuated the DHC accumulation and increased cell proliferation during hypoxia. Based on the amplitude and kinetics of DHC accumulation, the enzymatic desaturation of DHCs fulfills the criteria of an oxygen sensor across physiological hypoxic conditions, regulating the balance between biologically active components of ceramide metabolism.
LPC modeling with speech production constraints (2000)

Despite the approximations it supposes, performing LPC-based acoustico-articulatory inversion is justified in some applicative frameworks.By illustrating this assertion through experiments aiming at incorporating speech production constraints from the DRM model and from a factor-based model into an LPC modeling scheme, we promote the use of LPC-based inversion as an interface between Production Modeling and Automatic Speech Processing methods.
Carbon-rich acetylenic scaffolding: rods, rings and switches (2001)

Derivatives of tetraethynylethene (TEE, 3,4-diethynylhex-3-ene-1,5-diyne) and (E)-1,2-diethynylethene ((E)-DEE, (E)-hex-3-ene-1,5-diyne) provide a unique class of π-conjugated building blocks for modular construction of one- and two-dimensional carbon-rich scaffolds such as monodisperse, linearly π-conjugated oligomers extending in length beyond 10 nm or large macrocyclic all-carbon cores. Lateral functionalisation of these novel chromophores with donor–acceptor substituents strongly enhances their advanced materials properties and leads to exceptional third-order optical nonlinearities. New photochromic molecules were prepared which undergo photochemical cis → trans and trans → cis isomerisation without competing thermal isomerisation pathways, thereby paving the way for applications as light-driven molecular switches in optoelectronic devices.
Infants fed formula with added long chain polyunsaturated fatty acids have reduced incidence of respiratory illnesses and diarrhea during the first year of life (2014)

In healthy infants, formula with DHA/ARA was associated with lower incidence of common respiratory symptoms and illnesses, as well as diarrhea.
Tea Flavonoids: Bioavailability <i>In Vivo</i> and Effects on Cell Signaling Pathways <i>In Vitro</i> (2001)

The elucidation of the potential health benefits of tea beverage continues to be a focus of research in many laboratories. Beneficial effects of tea have been particularly evident in animal tumorigenesis models, with green and black tea frequently demonstrating similar effectivity. Human data are now emerging to support a beneficial role for tea in cardiovascular disease, but the data with respect to cancer risk at various sites remain inconclusive. The constituent flavonoids of green and black tea beverage are known to be potent antioxidants, and although this may be a major factor in explaining their biological activity, it appears that the gallated flavonoids in particular (e.g., epigallocatechin gallate and the gallated theaflavins) impact on a wide range of molecular targets that influence cell growth and more specifically pathways such as those involving angiogenesis. Data on the pharmacokinetic properties of tea flavonoids, primarily on the catechins and therefore related most closely to green tea, have provided indications of the plasma levels and circulating molecular forms that may be expected in humans following tea consumption. The structural complexity of black tea flavonoids, in particular the thearubigins, has hindered efforts to describe their bioavailability and to perform mechanistic studies. Recent studies on the effects of catechins and theaflavins on growth factor-, nuclear factor-kappaB-, and stress-mediated signal transductions are described in this review, where possible in relation to their bioavailability in vivo. These studies indicate that effects that may be relevant to both cancer and atherosclerosis are often observed at tea flavonoid levels that could realistically be encountered in vivo. However, more studies need to be performed using those molecular forms of tea flavonoids (methylated, sulfated, and glucuronidated conjugates) that are the major circulating species encountered following tea consumption. Such studies, combined with further human epidemiological and interventional data, should ultimately elucidate the full beneficial potential of tea beverage on human health.
Characterization of T cell-mediated responses in nonhealing and healing Leishmania major infections in the absence of endogenous IL-4 (1997)

IL-4 drives polarized Th2 responses, and differentiating Th2 cells down-regulate their sensitivity to IL-12. Therefore, the failure of BALB/c mice to heal Leishmania major infection could be due to an IL-4-dependent biased Th2 response or to a reduced capacity of Leishmania-specific Th cells to respond to IL-12. We examined the ability of CD4+ Th cells from L. major-infected wild-type and IL-4-deficient BALB/c mice to respond to IL-12. We show that the inability of normal and IL-4-deficient BALB/c mice to heal L. major infections is due to their inability to generate effective Th1 responses and not to persistent IL-4-dominated Th2 responses. Redirection of immune responses in vivo by administration of IL-12 or anti-CD4 mAb treatment in the early phase of infection (+/-12 days) allows both normal and IL-4-deficient BALB/c mice to heal their lesions by allowing them to develop an efficient Th1 response regardless of the presence or the absence of IL-4. Finally, on a population level, Ag-specific Th cells from infected animals induced to heal display a strongly elevated response to IL-12.