gebhart/patrepeval huggingface dataset:
Preparation and characterization of hydroxyapatite-coated iron oxide particles by spray-drying technique (2009)

Magnetic particles of iron oxide have been increasingly used in medical diagnosis by magnetic resonance imaging and in cancer therapies involving targeted drug delivery and magnetic hyperthermia. In this study we report the preparation and characterization of iron oxide particles coated with bioceramic hydroxyapatite by spray-drying. The iron oxide magnetic particles (IOMP) were coated with hydroxyapatite (HAp) by spray-drying using two IOMP/HAp ratios (0.7 and 3.2). The magnetic particles were characterized by way of scanning electronic microscopy, energy dispersive X-ray, X-ray diffraction, Fourier transformed infrared spectroscopy, flame atomic absorption spectrometry,vibrating sample magnetometry and particle size distribution (laser diffraction). The surface morphology of the coated samples is different from that of the iron oxide due to formation of hydroxyapatite coating. From an EDX analysis, it was verified that the surface of the coated magnetic particles is composed only of HAp, while the interior containsiron oxide and a few layers of HAp as expected. The results showed that spray-drying technique is an efficient and relatively inexpensive method for forming spherical particles with a core/shell structure.
Cancer Stem Cells as Mediators of Treatment Resistance in Brain Tumors: Status and Controversies (2007)

Malignant primary brain tumors are characterized by a short median survival and an almost 100% tumor-related mortality. Despite the addition of new chemotherapy regimes, the overall survival has improved marginally, and radiotherapy is only transiently effective, illustrating the profound impact of treatment resistance on prognosis. Recent studies suggest that a small subpopulation of cancer stem cells (CSCs) has the capacity to repopulate tumors and drive malignant progression and mediate radio- and chemoresistance. This implies that future therapies should turn from the elimination of the rapidly dividing, but differentiated tumor cells, to specifically targeting the minority of tumor cells that repopulate the tumor. Although there exists some support for the CSC hypothesis, there remain many uncertainties regarding theoretical, technical, and interpretational aspects of the data supporting it. If correct, the CSC hypothesis could have profound implications for the way tumors are classified and treated. In this review of the literature, we provide original data and hypotheses supporting alternative explanations and outline some of the therapeutic implications that can be derived.
Functional imaging in radiation therapy planning for head and neck cancer (2013)

Functional imaging and its application to radiotherapy (RT) is a rapidly expanding field with new modalities and techniques constantly developing and evolving. As technologies improve, it will be important to pay attention to their implementation. This review describes the main achievements in the field of head and neck cancer (HNC) with particular remarks on the unsolved problems.
Scalable Bloom Filters (2006)

Bloom filters provide space-efficient storage of sets at the cost of a probability of false positives on membership queries. The size of the filter must be defined a priori based on the number of elements to store and the desired false positive probability, being impossible to store extra elements without increasing the false positive probability. This leads typically to a conservative assumption regarding maximum set size, possibly by orders of magnitude, and a consequent space waste. This paper proposes Scalable Bloom Filters, a variant of Bloom filters that can adapt dynamically to the number of elements stored, while assuring a maximum false positive probability.
Analyzing the causes for Guilin traffic accidents and the countermeasures (2013)

Aiming at the severe problems in Guilin traffic safety,the causes for traffic accidents are analyzed by adopting the systematic engineering.The countermeasures are put forward by referencing the traffic experience from Hong Kong,which is to enhance the road supervision by using high technology,to promote vehicle safety performance by strengthening management,to improve the road situation by boosting the road planning,and to consolidate people's safety consciousness by creating traffic safety culture.
Myelin Proteomics: Molecular Anatomy of an Insulating Sheath (2009)

Fast-transmitting vertebrate axons are electrically insulated with multiple layers of nonconductive plasma membrane of glial cell origin, termed myelin. The myelin membrane is dominated by lipids, and its protein composition has historically been viewed to be of very low complexity. In this review, we discuss an updated reference compendium of 342 proteins associated with central nervous system myelin that represents a valuable resource for analyzing myelin biogenesis and white matter homeostasis. Cataloging the myelin proteome has been made possible by technical advances in the separation and mass spectrometric detection of proteins, also referred to as proteomics. This led to the identification of a large number of novel myelin-associated proteins, many of which represent low abundant components involved in catalytic activities, the cytoskeleton, vesicular trafficking, or cell adhesion. By mass spectrometry-based quantification, proteolipid protein and myelin basic protein constitute 17% and 8% of total myelin protein, respectively, suggesting that their abundance was previously overestimated. As the biochemical profile of myelin-associated proteins is highly reproducible, differential proteome analyses can be applied to material isolated from patients or animal models of myelin-related diseases such as multiple sclerosis and leukodystrophies.
No forced council amalgamations in NSW (2016)

Smiling nsw liberal Premier Mike Baird is showing himself to be yet another ruthless political gangster for the billionaire class and a wide range of people are uniting in resistance to his assaults on democracy.
Soil washing: From characterization to implementation (1995)

Only recently has soil washing begun to be applied to remediation of contaminated soils in the US. The experience gained during full-scale and large pilot-scale projects points to the importance of soil and site characterization in correctly evaluating the applicability of soil washing to a site and determining accurate cost estimates for its implementation. This paper will discuss actual case studies of various treatability and pilot study approaches that led to successful evaluation and implementation of soil washing remedies. Soil washing is applicable to a broad variety of chemical contaminants. Target contaminants include metals, radionuclides, pesticides, polychlorinated biphenyls, polynuclear aromatic hydrocarbons and petroleum hydrocarbons, as well as combinations of these contaminants. Because the contaminants noted above are deposited in the soils in a variety of forms, the unit operations necessary to treat the soil vary. It is the diversity of the available treatment alternatives, and the ability to use the units in a variety of process flow configurations that result in a very broad definition of soil washing.
Adobe Photoshop CS4 on Demand (2008)

Adobe Photoshop CS4 on DemandWhat you need, when you need it!Need answers quickly? Adobe Photoshop CS4 on Demand provides those answers in a visual step-by-step format. We will show you exactly what to do through lots of full color illustrations and easy-to-follow instructions.Inside the Book Improve productivity with the CS4 interface and templates Use automatic layer alignment and blending to work with objects Use live filters to vie w and modify the results of opening files Use more precise color correction to enhance a photo Easily convert images to black and white Use image trickery to change or enhance an image Create eye-catching bevels and special effects Transform plain text into a show-stopping image Create web animation sequences the easy way Use tool presets to construct the right tool for the right job Test content on different target devicesBonus Online Content Register your book at queondemand.com to gain access to: Workshops and related files Keyboard shortcutsVisit the author site: perspection.com
Neuropsychological consequences of chronic bilateral stimulation of the subthalamic nucleus in Parkinson's disease (2000)

The aim of this study was to examine possible neuropsychological changes in patients with advanced idiopathic Parkinson's disease treated with bilateral deep brain stimulation (DBS) of the subthalamic nucleus (STN). Eleven patients (age = 67 +/- 8 years, years with Parkinson's disease = 15 +/- 3, verbal IQ = 114 +/- 12) were evaluated (in their best 'on state') with tests assessing processes reliant on the functional integrity of frontal striatal circuitry, prior to the procedure (n = 11), at 3-6 months (n = 11) and at 9-12 months (n =10) post-operatively. Six of these patients were older than 69 years. Despite clinical motor benefits at 3-6 months post-operative, significant declines were noted in working memory, speed of mental processing, bimanual motor speed and co-ordination, set switching, phonemic fluency, long-term consolidation of verbal material and the encoding of visuospatial material. Declines were more consistently observed in patients who were older than 69 years, leading to a mental state comparable with progressive supranuclear palsy. 'Frontal' behavioural dyscontrol without the benefit of insight was also reported by half (three of six) of the caregivers of the elderly subgroup. At 9-12 months postoperative, only learning based on multiple trials had recovered. Tasks reliant on the integrity of frontal striatal circuitry either did not recover or gradually worsened over time. Bilateral STN DBS can have a negative impact on various aspects of frontal executive functioning, especially in patients older than 69 years. Future studies will evaluate a larger group of patients and examine the possible reversibility of these effects by turning the DBS off.
Synthesis and Properties of NaSICON‐type LATP and LAGP Solid Electrolytes (2019)

Inorganic solid electrolytes play a critical role in solid-state lithium batteries achieving high safety levels and high energy densities. The synthetic approaches to solid electrolytes are important for both fundamental research and practical applications. Li<sub>1+x</sub> Al<sub>x</sub> Ti<sub>2-x</sub> (PO<sub>4</sub> )<sub>3</sub> (LATP) and Li<sub>1+x</sub> Al<sub>x</sub> Ge<sub>2-x</sub> (PO<sub>4</sub> )<sub>3</sub> (LAGP) are two representative solid electrolytes with a sodium superionic conductor (NaSICON) structure. Herein, LATP and LAGP solid electrolytes are reviewed from the synthesis perspective, and correlated with their structure and conductive properties, as well as their electrochemical applications in batteries. First, the solid- and liquid-based synthetic methods to LATP and LAGP solid electrolytes and the key influencing factors are described. Second, the crystal structures and phase purities obtained from different synthetic approaches are introduced. Third, the conductive mechanisms, composition effects, and synthetic effects on the conductivities of LATP and LAGP solid electrolytes are compared. Fourth, the electrochemical applications of these two solid electrolytes in full batteries are discussed, including roles as solid electrolytes, composite components in electrodes, and surface coatings on electrodes. In the last section, a brief outlook is provided on the future development of NaSICON-type solid electrolytes for all-solid-state batteries.
Necrotizing Fasciitis Due to (1970)

Necrotizing fasciitis due to group A β-hemolytic streptococci is a serious acute cutaneous infection which is distinct from erysipelas and other ulcerating and gangrenous processes. It is characterized by rapidly spreading, ill-defined erythema followed by painless ulceration and necrosis along fascial planes. A satisfactory outcome depends on early recognition, and vigorous medical and surgical management.
[The effect of Ca-diethylenetriamine pentaacetate on the bio-behavior of tumor-affine metal complexes]. (1992)

The complexon CaDTPA was injected into tumour-bearing mice in concentrations of 0.05, 0.1, 0.3, and 0.6 mole/l (pH:6) 30 min after the 169Yb-injection. 100 microliters of a 0.3 M CaDTPA solution were injected at different time points (simultaneously, 2, 5, 10, 20, 30, 40 and 50 min, 1, 1.25, 1.5, 2.5 and 10 h) after 169Yb-citrate injection. The animals were killed 24 h after radionuclide administration. A strong radioactivity decrease was observable 24 h p.i. not only in blood, liver, spleen, muscle and bone but also in the tumour if CaDTPA was administered within the first 2 h after ytterbium injection. Thereafter no change in radioactivity could be achieved by DTPA. A time phase in which the Yb could be eliminated from the tissues by means of DTPA (time intervals < 2 h) was distinguishable from a time phase in which it was not attainable for DTPA (time intervals > 5 h). This indicates that the incorporation of Yb into the cells is completed after 5 h and that the metals are intracellularly bound, probably to the lysosomes. Improvements of the scintigraphic tumour detection cannot be expected from the use of complexons.
Automatic fluid velocity detection methods for digital angiography (2002)

Digital angiography is a medical procedure that is used to visualize blood flow. A radioisotope is injected through a catheter that has been maneuvered into the area to be visualized. A sequence of X-ray images is then captured. Digital subtraction is performed between X-ray images captured before and after the dye injection in order to visualize blood flow, without obscuring anatomical structures. Many hemodynamic parameters can now be determined, including blood how velocity. What is lacking in this procedure, however, is a measure by which the method for velocity determination can be verified. Here, the authors present the first step towards verification of automatic flow velocity calculation. They offer an objective comparison of four methods for automatic fluid velocity calculation in which the actual flow velocity is known. They give a concise description of the theory behind and implementation of each method. Finally, the authors discuss the results of applying the four techniques to their experimental data.
Predicting breast cancer survivability using random forest and multivariate adaptive regression splines (2011)

In this paper, we propose a hybrid of random forest and multivariate adaptive regression splines algorithms for building a breast cancer survivability prediction model. We use random forest to perform a preliminary screening of variables and to receive a importance ranks. Then, the new dataset is extracted from initial WDBC dataset according to top-k important predictors and is input into the MARS procedure, which is responsible for building interpretable models for predicting breast cancer survivability. The capability of this combination method is evaluated using basic performance measurements (e.g., accuracy, sensitivity, and specificity) along with a 10-fold cross-validation. Experimental results show that the proposed method provides a higher accuracy and a relatively simple model.
Crowdsourcing Accessibility Related Information From POI-Destinations in Finland (2011)

The use of Social media is growing fast. The objective of the SosPromo project was to investigate the possibilities of Social Media tools and processes as a rapid way of information collection and sharing to enable and support the mobility of the selected user group, people with some movement reducing factor. The actual implementation in SosPromo-project focused on crowdsourcing accessibility information from Points Of Interest, POIs (e.g. restaurants, cafes, shops) especially in the Helsinki capital region in Finland. This information can be used for personalised journey planning especially with disabled or elderly users or persons with temporary mobility restrictions, e.g. when moving in a city with a small child in a push chair. The introduced SosPromo concept enables further information sharing between different user groups.
All-Optical WDM/TDM Star-Bus Network using Optical Amplifiers (1995)

We propose a broadband WDM/TDM star-bus network using EDFAs. Taps with different tap ratios are used to reduce the dynamic range of the power at the receivers. A network with NM customers can be implemented using N buses (wavelength assignments) and using optical TDM to support M users per bus. Three different variations and their protocols have been considered and compared. Calculation methods and their algorithms are devised to determine the number of stations to be supported for buses of different types of taps. By combining the advantages of the star and bus topologies along with the use of amplifiers and TDM technology, it becomes more efficient for a large number of customers to share a broadband network such as the Metropolitan Area Network.
RF MEMS technology (2007)

Abstract Recently, to meet the demands of multimode/multiband functions for the next generation communication systems, RF MEMS technology is being developed for the reconfigurable transceiver system. In this article, RF MEMS devices such as switches, high‐Q inductors, and high‐Q resonators are reviewed for their operating principles and device structures, as well as the reliability and commercial issues. Single pole single throw (SPST)‐type MEMS switches show characteristics superior to solid‐state switches in the aspects of insertion loss, isolation, and linearity. Single pole multithrow (SPMT) switches will enable ultra small‐sized cellular phones, but insertion loss and coupling between channels should be improved. For a high‐Q inductor, out‐of‐plane inductors show improved results, and an inductor with a Q‐factor of 75 at 1GHz has been fabricated by using the internal stress of a MoCr film. The MEMS inductor improves the performance of a voltage controlled oscillator (VCO), but proper hermetic packaging and standard libraries are also necessary for mass production. The MEMS resonator can operate up to 1.4 GHz and can be used as an oscillator for the timing device as well as component of the filter circuit. The SiTime Company recently has started delivery of a product with performance similar to the quartz oscillator, in which they solved the reliability issues by modifying the annealing and vacuum packaging. Copyright © 2007 Institute of Electrical Engineers of Japan© 2007 Institute of Electrical Engineers of Japan. Published by John Wiley & Sons, Inc.
Satellite Control System (1979)

International Telemetering Conference Proceedings / November 19-21, 1979 / Town and Country Hotel, San Diego, California
Coded Phase/Frequency Modulation (1986)

Channel coding combined with expanded signal sets has been shown [1] to improve error performance over uncoded modulation without expanding the bandwidth of the transmitted signals. In this paper, new coded modulation formats defined over an expanded set of signals varying both in phase and frequency are presented. The new schemes combine FSK and PSK modulation and make use of trellis coding and Viterbi decoding to improve error performance over uncoded modulation. The free Euclidean distance is calculated for several classes of codes, and upper bounds and simulation results are also presented for some simple codes. The spectral characteristics of the proposed coded modulation formats are evaluated and compared to conventional two-dimensional modulation formats. Differential encoding and various extensions of the basic scheme are also discussed.
Temperature Overshoot in Shock Waves (1966)

Temperature associated with the logitudinal thermal velocities overshoots for M1 &gt; (9/5)½ for monatomic gases. The overshoot and the location of the maximum temperature are functions of M1.
THE BRAND CAPABILITY VALUE OF INTEGRATED MARKETING COMMUNICATION (IMC) (2005)

Practitioners perpetually question whether they are spending the right amount of money on the right marketing activities to optimize sales, profitability, brand equity, and shareholder value. This perennial problem is perhaps even more salient today, as organizations increasingly begin to recognize the value of intangible assets and question the extent to which marketing should be viewed as an investment (as opposed to an expense). This paper introduces the notion of brand capability within a tangible-intangible asset valuation framework. Specifically, a model is developed to assess the impact of integrated marketing communication on brand equity by leveraging capability-enhancing marketing expenses to economic values through the use of specific combinations of expense-leveraged value indices.
An improved strategy for a genetic assay for site-specific proteolysis. (2001)

We have previously reported a genetic assay that is suitable for the study of substrate specificity of a protease in vivo, and herein present a simplified version of the method. In this procedure, expressed in Saccharomyces cerevisiae by using the constitutive alcohol dehydrogenase promoter is a fusion protein in which a transcription factor is linked to the intracellular domain of an integral membrane protein by a protease substrate sequence. Following this, a protease is expressed by using the inducible GAL promoter in the same yeast cells. The cleavage of the substrate sequence by the specific protease results in the release of the transcription factor and subsequent activation of reporter genes in nucleus. Since the expression of a protease is strictly under the control of the inducible GAL promoter, false substrate sequences that are cleaved by endogenous yeast proteases can be easily recognized and eliminated from further characterization. This suggests that the modified strategy provides an efficient tool for the analysis of substrate sequences of a protease in vivo.
Rosuvastatin and vascular dysfunction markers in pulmonary arterial hypertension: a placebo-controlled study (2008)

We investigated whether chronic rosuvastatin administration could improve the abnormalities of the circulating levels of vascular dysfunction markers in pulmonary arterial hypertension (PAH). Sixty patients, aged 13 to 60 years, with idiopathic (N = 14) or congenital heart disease-associated PAH (N = 46) were equally but randomly assigned to rosuvastatin treatment (10 mg a day, orally) or placebo for 6 months in a blind fashion. Plasma levels of P-selectin, tissue-plasminogen activator and its inhibitor as well as von Willebrand factor antigen were measured by enzyme-linked immunoassay before and after 1, 3, and 6 months of treatment. Baseline levels of biomarkers were elevated (68, 16, 45 and 46% increase relative to controls, for P-selectin, von Willebrand factor antigen, tissue-plasminogen activator and its inhibitor, respectively; P < 0.001). P-selectin values at baseline, 1, 3, and 6 months were 39.9 +/- 18.5, 37.6 +/- 14.6, 34.8 +/- 14.6, and 35.4 +/- 13.9 ng/mL, respectively, for the rosuvastatin group and 45.7 +/- 26.8, 48.0 +/- 26.9, 48.1 +/- 25.7, and 45.7 +/- 25.6 ng/mL for the placebo group. The P-selectin level was lower in the rosuvastatin group compared with placebo throughout treatment (P = 0.037, general linear model). A trend was observed towards a decrease in tissue-plasminogen activator in the statin group (16% reduction, P = 0.094), with no significant changes in the other markers. Since P-selectin is crucial in inflammation and thrombosis, its reduction by rosuvastatin is potentially relevant in the pathophysiological scenario of PAH.