gebhart/patrepeval huggingface dataset:
Influence of location, fluid flow direction and bone tissue maturity on the permeability of vertebral end-plates (2005)

Non renseigné
Statistical analysis plan for the HEAT trial: a multicentre randomised placebo-controlled trial of intravenous paracetamol in intensive care unit patients with fever and infection (2013)

We developed an SAP for the HEAT trial, and produced a mock Consolidated Standards of Reporting Trials diagram and tables. Our prespecified SAP accords with high-quality standards of internal validity and should minimise future analysis bias.
Investigation of the Influence of Different Asperity Contact Models on the Elastohydrodynamic Analysis of a Conrod Small-End/Piston Pin Coupling (2018)

<div class="section abstract"><div class="htmlview paragraph">Bearings represent one of the main causes of friction losses in internal combustion engines, and their lubrication performance has a crucial influence on the operating condition of the engine. In particular, the conrod small-end bearing is one of the most critical engine parts from a tribological point of view since limited contact surfaces have to support high inertial and combustion forces. In this contribution an analysis is performed of the tribological behavior of the lubricated contact between the piston pin and the conrod small-end of a high performance motorbike engine. A mass-conserving algorithm is employed to solve the Reynolds equation based on a complementarity formulation of the cavitation problem. The analysis of the asperity contact problem is addressed in detail. A comparison between two different approaches is presented, the former based on the standard Greenwood/Tripp theory and the latter based on a complementarity formulation of the asperity contact problem. Differently from the Greenwood/Tripp method, the complementarity formulation needs only one parameter related to the roughness of the mating surfaces to be set and allows a solution to be obtained without the need of an iterative procedure thus avoiding convergence issues. Similar results are obtained comparing both the approaches used to solve the asperity contact problem. However, such an agreement is only reached after an appropriate calibration of the model input data is performed; a remarkable sensitivity of the results obtained using the Greenwood/Tripp model to the adjustment parameters is found and highlighted. Finally, a full model validation is performed by comparing the results obtained adopting the proposed algorithm, using the implementation of the Greenwood/Tripp asperity contact model, with those obtained adopting the commercial software AVL Excite Power Unit.</div></div>
[University of Florida and Center for Drug Discovery through a visiting scholar's view]. (2001)

The article introduces University of Florida and the Center for Drug Discovery based on the author's experience as a visiting research fellow.
Cognitive Temporary Bypassing for Reliable Multi-Hop Transmission in Wireless Ad Hoc Networks (2010)

Multi-hop wireless ad hoc networks suffer from temporary link error due to fading. In order to improve packet transmission reliability and achieve efficient transmission in fading environment, a new cognitive temporary bypassing scheme is proposed based on a cross-layer approach and cognitive behavior of local nodes. The proposed scheme enables neighboring nodes to prepare and create a temporary bypass for lost-packets. This is done by monitoring message packets that include information of the multi-hop route and link-acknowledgement. The scheme also includes an anti-collision function that is necessary to prevent contention among multiple bypassing nodes. Packet success probability with the proposed scheme is studied both by theoretical analysis and time-domain computer simulation for Rayleigh faded single- and multi-hop links. Network simulation using a modified QualNet simulator validate that packet success probability is remarkably improved with the scheme for maximum Doppler frequencies up to 30Hz.
An efficient algorithm for classical density functional theory in three dimensions: Ionic solutions (2010)

Classical density functional theory (DFT) of fluids is a valuable tool to analyze inhomogeneous fluids. However, few numerical solution algorithms for three-dimensional systems exist. Here we present an efficient numerical scheme for fluids of charged, hard spheres that uses O(N log N) operations and O(N) memory, where N is the number of grid points. This system-size scaling is significant because of the very large N required for three-dimensional systems. The algorithm uses fast Fourier transforms (FFTs) to evaluate the convolutions of the DFT Euler-Lagrange equations and Picard (iterative substitution) iteration with line search to solve the equations. The pros and cons of this FFT/Picard technique are compared to those of alternative solution methods that use real-space integration of the convolutions instead of FFTs and Newton iteration instead of Picard. For the hard-sphere DFT, we use fundamental measure theory. For the electrostatic DFT, we present two algorithms. One is for the "bulk-fluid" functional of Rosenfeld [Y. Rosenfeld, J. Chem. Phys. 98, 8126 (1993)] that uses O(N log N) operations. The other is for the "reference fluid density" (RFD) functional [D. Gillespie et al., J. Phys.: Condens. Matter 14, 12129 (2002)]. This functional is significantly more accurate than the bulk-fluid functional, but the RFD algorithm requires O(N(2)) operations.
Bandwidth, Area Efficient And Target Device Independent Ddr Sdram Controller (2008)

The application of the synchronous dynamic random access memory (SDRAM) has gone beyond the scope of personal computers for quite a long time. It comes into hand whenever a big amount of low price and still high speed memory is needed. Most of the newly developed stand alone embedded devices in the field of image, video and sound processing take more and more use of it. The big amount of low price memory has its trade off – the speed. In order to take use of the full potential of the memory, an efficient controller is needed. Efficient stands for maximum random accesses to the memory both for reading and writing and less area after implementation. This paper proposes a target device independent DDR SDRAM pipelined controller and provides performance comparison with available solutions.
Analysis of Eddy Currents in a Resistive Coating of the Injection Kicker Beam Tube (1995)

This report talks about the Analysis of Eddy Currents in a Resistive Coating of the Injection Kicker Beam Tube
Regularization using the MDL principle: estimation of regularization parameters for regions containing discontinuities (1999)

Regularization is widely utilized as an effective means of solving ill-posed problems, where the solution cannot be uniquely determined from the observed data alone. In most past studies, regularization is applied by setting the regularization parameter as a constant over the entire given image plane. The objective of this to derive an adequate solution adapted to the local properties of the object. A method is proposed in which the regularization parameter is determined for each local area of an image by the MDL (minimum description length) principle. More precisely, the following method is proposed. The description length, which represents the adequateness of the solution derived from the penalty functional and the stabilization functional, and the description length of the regularization parameter distribution on the image, are calculated. Then, the regularization parameter is estimated for each local area based on the MDL principle so that the sum of those description lengths is minimized. As a result, the regularization parameter is determined for each discontinuous area and each smooth area of the object. Lastly, the proposed method is applied to optical flow estimation, and its effectiveness is demonstrated by the results of experiments. © 1999 Scripta Technica, Syst Comp Jpn, 30(8): 61–71, 1999
Micropropagation végétative in vitro d'Ailanthus vilmoriana (1988)

info:eu-repo/semantics/published
Design, construction and application of a fully automated equimolar peptide mixture synthesizer (1992)

A fully automated peptide synthesizer has been constructed that is capable of the synthesis of equimolar peptide mixtures and the simultaneous synthesis of 36 individual peptides. The synthesizer was constructed from a workstation of our own design utilizing a Zymark robot arm. A Macintosh II computer coordinates the movements of the robotic arm, the switching of over 40 solenoid valves and the monitoring of sensors in the workstation. The robot hands are used to deliver solvents from pressurized spigot lines and to pipet amino acid solutions from reservoirs to an array of reaction vessels. Liquid dispensing, reagent mixing and solvent removal are controlled from a multifunction I/O board in the computer. The design features of the synthesizer are presented, as well as the characterization of multiple individual peptides, a simple mixture of 19 components, and a complex mixture of 15,625 components.
Hydridic Nature of the "Lower Oxide of Thorium" (1962)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTHydridic Nature of the "Lower Oxide of Thorium"Leonard I. Katzin, Louis Kaplan, and Thomas SteitzCite this: Inorg. Chem. 1962, 1, 4, 963–964Publication Date (Print):November 1, 1962Publication History Published online1 May 2002Published inissue 1 November 1962https://pubs.acs.org/doi/10.1021/ic50004a065https://doi.org/10.1021/ic50004a065research-articleACS PublicationsRequest reuse permissionsArticle Views52Altmetric-Citations9LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Formate dehydrogenase from <i>Clostridium pasteurianum</i> (1985)

Formate dehydrogenase from Clostridiun pasteurianum catalyses the interconversion of CO 2 , and formate. It is a complex enzyme, containing molybdenum, iron, acid‐labile sulfur and pterin. Redox potentiometry and EPR analysis reveal two spectrally and thermodynamically distinct iron‐sulfur clusters, with g 1.87, 1.95 and 2.05 ( E m8 ‐318 mV) and g 1.92 and 2.05 ( E m8 ‐372 mV), both present at approx. 0.3 spins per enzyme. There is also a free radical signal centered near g 2.005 which we attribute to the pterin, perhaps in its anionic semiquinone form. This signal disappears on oxidation ( E m8 ‐150 mV), but is not reduced further at pH 8. It is present at approx. 0.8 spins per enzyme. No EPR signals attributable to the molybdenum were detected.
Re: Nephron Sparing Surgery for Renal Cell Carcinoma in Von Hippel-Lindau Disease (1996)

No AccessJournal of UrologyClinical Urology: Letter to the Editor1 Aug 1996Re: Nephron Sparing Surgery for Renal Cell Carcinoma in Von Hippel-Lindau Disease McClellan M. Wather, and W. Marston Linehan McClellan M. WatherMcClellan M. Wather More articles by this author , and W. Marston LinehanW. Marston Linehan More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(01)65891-9AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "Re: Nephron Sparing Surgery for Renal Cell Carcinoma in Von Hippel-Lindau Disease." The Journal of Urology, 156(2), pp. 480–481 References 1 : Characterization of the renal pathology of a familial form of renal cell carcinoma associated with von Hippel-Lindau disease: clinical and molecular genetic implication. J. Urol.1995; 153: 22. Abstract, Google Scholar 2 : Parenchymal sparing surgery in patients with hereditary renal cell carcinoma. J. Urol.1995; 153: 913. part 2. Link, Google Scholar 3 : The natural history of renal lesions in von Hippel-Lindau disease: a serial CT study in 28 patients. AJR1992; 159: 1229. Google Scholar 4 : Enucleation procedures in patients with multiple hereditary renal tumors. World J. Urol.1995; 13: 248. Google Scholar 5 : Evaluation of color Doppler intraoperative ultrasound in parenchymal sparing renal surgery. J. Urol.1994; 152: 1984. Link, Google Scholar 6 : Germline mutations in the von Hippel-Lindau disease tumor suppressor gene: correlations with phenotype. Hum. Mut.1995; 5: 66. Google Scholar Urologic Oncology Section, NIH/SB/COP/DCT/NCI, 9000 Rockville Pike, Building 10. Room 2B-43, 10 Center Drive MSC 1502, Bethesda, Maryland 20898-1502.© 1996 by American Urological Association, Inc.FiguresReferencesRelatedDetails Volume 156Issue 2August 1996Page: 480-481 Advertisement Copyright & Permissions© 1996 by American Urological Association, Inc.MetricsAuthor Information McClellan M. Wather More articles by this author W. Marston Linehan More articles by this author Expand All Advertisement PDF DownloadLoading ...
Experimental Determination of Elastic Anisotropy and Biot's Constant in a Saudi Arabian Reservoir Sandstone (2002)

Abstract Rock mechanical triaxial and hydrostatic tests were conducted on 1.5-inch diameter sandstone samples obtained from four wells. A total of 23 different depth intervals were tested, at pressures representing the in-situ reservoir conditions. Static elastic moduli (Young's modulus and Poisson's ratio) and static Biot's constant were determined from the results of the triaxial tests. Dynamic elastic constants of selected rock samples were determined from ultrasonic compressional and shear wave transmission data obtained under hydrostatic stress conditions through vertical, horizontal and 45-degree-oriented samples. Porosity and permeability measurements were also made on corresponding sister samples. Wave velocities and the computed dynamic moduli indicated the existence of stress-induced elastic anisotropy, which was found to decrease with increasing confining pressure. Biot's constant values in planes parallel and perpendicular to the bedding were found to be nearly the same, indicating that the anisotropy in the wave velocities and dynamic elastic moduli does not translate directly into anisotropy in the Biot's constant. However, the Biot's constant in both planes decreased significantly with hydrostatic stress, indicating a stress-dependency. The static Biot's constant obtained from triaxial tests also decreased with increase in axial stress, demonstrating a significant axial stress-dependency as well. The results were found to be in general agreement with the literature.
Involvement of epidermal growth factor in inducing obesity in ovariectomized mice (1993)

Ovariectomy (Ovx) of mice significantly increases the epidermal growth factor (EGF) concentration in the submandibular gland. To elucidate the role of this elevated EGF in obesity of Ovx mice, we examined the effects of sialoadenectomy (Sx) and anti-EGF rabbit antiserum administration on the body weight (BW) gain and carcass fat deposition in Ovx animals. Studies were performed in four groups of mice consisting of control, Ovx, Ovx+Sx, and Ovx+anti-EGF groups. Ovx increased the BW gain compared with the control animals, whereas Sx and anti-EGF significantly reduced it. Although the relative weights (weight ratio to BW) of the liver and kidney were not significantly changed by Ovx, Sx, or anti-EGF treatment of Ovx mice, the relative weights of mesenteric, parametrial, and subcutaneous fat tissues were increased in Ovx mice, and this increase was significantly reduced by Sx or anti-EGF administration. Ovx induced adipocyte hypertrophy, and this effect was eliminated by Sx and anti-EGF. Moreover, acyl-CoA synthetase mRNA level was increased by Ovx, and this increase was reduced by Sx and anti-EGF in mesenteric fat tissue. These findings suggest that elevation of EGF may play a role in the induction of obesity in Ovx mice.
An Industrial Hygiene Study of Flame Cutting in a Granite Quarry (1969)

Abstract The use of flame cutting in a granite quarry has been evaluated and found to result in noise and dust exposures which differ from those noted with conventional quarrying operations. Flame cutting units are severe noise sources and hearing conservation programs are required where they are used. The dust generated by flame techniques includes crystalline material generated during the spalling action of the flame. A high percentage of this material is melted in the flame and forms spherical particles. A fume with a diameter less than 0.10 micron is also generated by the flame. Dust exposures on flame operations are routinely below 10 mppcf when evaluated by conventional techniques. Exposure to the rock fume warrants additional study.
Comparative Bioavailability/Bioequivalence of Two Different Sertraline Formulations (2011)

An open-label, randomised, crossover single dose study, using 2 periods x 2 sequences, with a minimum washout period of 4 weeks, was conducted in order to assess the comparative bioavailability of two formulations of sertraline hydrochloride (CAS 79617-96-2) 100 mg tablets. Plasma samples were obtained at intake (baseline) and at +1 h, +2 h, +3 h, +4 h, +5 h, +6 h, +7 h, +8 h, +9 h, +12 h, +24 h, +48 h, +72 h and +96 h post administration. Sertraline plasma concentrations were determined by high pressure liquid chromatography with tandem mass detection (HPLC-MS/MS) and the lower limit of quantification was set at 100.15 pg/mL. Pharmacokinetic parameters used for bioequivalence assessment (AUClast, AUCinf and Cmax) were determined by non-compartmental analysis. Classical 90 % confidence intervals (90CI) were calculated for the overall sample, and for males and females separately, and gender effects were investigated using an appropriate model. The results showed that overall classical 90CI were 84.55-100.32 % for Cmax 86.96-98.68 % for AUClast, and 86.79-98.93 for AUCinf, that is, they were all within the predefined ranges for bioequivalence acceptance. Separate gender analysis showed very similar results for males and females when analysed independently, and no gender effects were detected in bioequivalence analysis (p > 0.05). It may be therefore concluded that the evaluated formulations are bioequivalent in terms of rate and extent of absorption.
Unconventional processing of the 3' termini of the Epstein-Barr virus DNA polymerase mRNA. (1993)

Northern blot analysis of the Epstein-Barr virus DNA polymerase mRNA identified two discrete sizes of virally encoded polymerase transcripts, 5.08 kb detected in strains P3HR1, Raji, W-91, and FF-41 and 3.7 kb detected solely in the prototype B95-8 strain. 3' S1-nuclease mapping and analysis of cDNA sequence generated by RNA-based PCR demonstrated that the 3.7-kb polymerase mRNA from B95-8 terminates 484 base pairs downstream of the open reading frame in a region of the genome remarkable for its lack of an apparent polyadenylylation signal. Moreover, between the cleavage point and the poly(A) tract of the cDNAs are a series of inserted nucleotides, mostly adenosine and uridine residues of unknown origin. A similar analysis of the 3' terminus of the 5.0-kb mRNA from the other cell lines revealed that polyadenylylation occurs 1.4 kb downstream of the B95-8 terminus. This region is deleted in B95-8, which accounts for the alternate upstream terminus used in B95-8. Like the 3.7-kb terminus, the 5.0-kb terminus lacks a canonical polyadenylylation signal, but contains a rarely used UAUAAA sequence 32 bp upstream of the poly(A) tail. These results indicate that the mRNA encoded by the Epstein-Barr virus DNA polymerase gene is polyadenylylated at two different termini without the use of canonical signals, raising the possibility of involvement of a virus-encoded factor in 3' processing of this message.
Modular Chemistry with Aluminum Phosphanides: Cluster Formation of (AlP)n (n=3,6,7), Al4P3, and Al4Li4P6 Frameworks (2000)

The Al3P3 heterocycle 1 is formed in 94 % yield by the reaction of the primary silylphosphane 6 a with Me3Al in toluene at 70 °C. While 1 crystallizes in an isomerically pure form, in which the six-membered Al3P3 ring prefers the chair conformation and the P-H hydrogen atoms adopt exo positions, it isomerizes in solution to give different diastereomers as shown by 1H and 31P NMR spectroscopy. Intermolecular cyclocondensation of 1 at 110 °C in toluene leads, under liberation of methane, to the distorted hexameric-prismatic (AlP)6 cluster 2 in 98 % yield. The capability of 1 to function as a building block was further used for the synthesis of the solvent-separated ion pair [Li(thf)2]+ [(Me2Al)4(PR)3]− (3) which was prepared by a one-pot reaction of 1 with nBuLi and Me2AlCl in 15 % yield. The structure of 3 was established by an X-ray diffraction analysis. Double deprotonation at phosphorus in 1 with RPLi2 (R=iPr3Si) (molar ratio 1:2), and subsequent transformation of the reaction mixture with Me3Al afforded the novel donor-solvent-free cluster 4 in 62 % yield. The latter consists of a rhombododecahedral Al4Li4P6 framework, in which the Li centers are three-coordinate. The reaction of the silylphosphane 6 b with the trimethylamine adduct of alane furnishes not only the hexamer (RPAlH)6 (R=(iPrMe2C)Me2Si) but also the corresponding heptamer 5, which has a nonregular polyhedral (AlP)7 framework and represents the first cluster of this type.
Fiber Optic Sensors With Internal Referencing (1989)

The main problem with amplitude modulating type sensors is that any variation in the intensity of the optical signal which occurs throughout the sensing system is interpreted by the photodetector as resulting from the sensor itself and is reflected as an error in the sensed parameter. To account for these errors, a referencing technique with the signal and reference channels separated in the time domain over the same fiber link can be used. Selected sensing and signal processing techniques involving temporally separated signal and referencing channels are described. A transition from the time into the frequency domain is also discussed. Experimental data are presented.
Predaceous Neuropterans in Georgia and Kansas Pecan Trees (1994)

Fourteen species, six genera, and three families of Neuroptera were found in Georgia and Kansas pecan tree canopies. Chrysoperla rufilabris (Burmeister) was the most numerous green lacewing collected in both areas. Chrysoperla carnea Stephens was the second most abundant green lacewing collected. Micromus posticus (Walsh) and Hemerobius humulinus L. were the two most commonly collected brown lacewings in both regions. Green lacewing populations were 6 to 11-fold larger in Kansas than in Georgia. Brown lacewing populations were slightly larger in Georgia than in Kansas. Green lacewing seasonal incidence was similar in both areas, with the late season peak occurring 2 to 3 wks later in Georgia than in Kansas. Brown lacewing seasonal incidence varied considerably between regions and years. Coniopteryx westwoodi Melander was the primary microneuropteran species collected. In Kansas, pesticide applications had significant effect on lacewing populations in some years but not others. Carbaryl applications had greater effect on population levels than phosalone.