gebhart/patrepeval huggingface dataset:
ChemInform Abstract: Direct Oxyfunctionalization at Unactivated Sites. Synthesis of 5β‐ Hydroxysteroids by Perfluorodialkyloxaziridines. (1995)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Studies on the induction of immunologic unresponsiveness. I. Effects of endotoxin and phytochemagglutinin. (1967)

Summary The time course of the inhibition of establishment of immunologic unresponsiveness to human γ-globulin (HGG) in adult mice by endotoxin (ET) has been studied. ET prevents the establishment of unresponsiveness in C57BL/6J and A/J mice only if given up to 2 days after injection of HGG. ET given before or 3 or more days after HGG is ineffective. The effect of ET on induction of unresponsiveness is apparently independent of the granulopectic activity of the reticuloendothelial system (RES), as measured by clearance of colloidal carbon from the circulation, since ET is effective when the activity of the RES is either elevated or depressed. One dose of ET before HGG eliminates the ability of the ET given after HGG to prevent the establishment of immunologic unresponsiveness, although the granulopectic activity of the RES is elevated. The amount of HGG associated with spleen cells is comparably elevated above controls in animals treated with ET before or after HGG. The effect is not the result of complex formation between ET and HGG. Cortisone given at the time of ET does not alter the effect of ET. Phytohemagglutinin (PHA) induces an intense proliferation of spleen cells in vivo as measured by incorporation of tritiated thymidine and increase in cell number, but has no effect on the induction of immunologic unresponsiveness. Neither ET nor PHA affect the unresponsive state which has been induced in neonatal life.
ON THE ANDROMIMETIC ACTION OF THE ADRENALS OF IMMATURE HYPOPHYS-ECTOMIZED-GONADECTOMIZED RATS (1951)

It is generally agreed that under certain pathological conditions the adrenals are capable of secreting huge amounts of androgenic substances. The pituitary control of this adrenal function is, however, not fully understood. Clinical studies led Thorn & Forsham (1949) to the conclusion that the adrenocorticotrophic hormone (ACTH) is able to induce an increased release of andromimetic substances from the adrenals, while Howard et al. (1950) assume that a combined action of ACTH and of the interstitial cell stimulating hormone (ICSH) is necessary. It has also been suggested (Thorn & Forsham) that the secretion of adrenal androgens in children at puberty is initiated by the increased secretion of pituitary luteotrophin (LTH).
Asymptotic locally optimal detector for large-scale sensor networks under the Poisson regime (2005)

We consider distributed detection with a large number of identical binary sensors deployed over a region where the phenomenon of interest (POI) has spatially varying signal strength. Each sensor makes a binary decision based on its own measurement, and the local decision of each sensor is sent to a fusion center using a random access protocol. The fusion center decides whether the event has occurred under a global size constraint in the Neyman-Pearson formulation. Assuming homogeneous Poisson distributed sensors, we show that the distribution of "alarmed" sensors satisfies the local asymptotic normality (LAN). We then derive an asymptotically locally most powerful (ALMP) detector optimized jointly over the fusion form and the local sensor threshold under the Poisson regime. We establish conditions on the spatial signal shape that ensure the existence of the ALMP detector. We show that the ALMP test statistic is a weighted sum of local decisions, the optimal weights being the shape of the spatial signal; the exact value of the signal strength is not required. We also derive the optimal threshold for each sensor. For the case of independent, identically distributed (iid) sensor observations, we show that the counting-based detector is also ALMP under the Poisson regime. The performance of the proposed detector is evaluated through analytic results and Monte Carlo simulations and compared with that of the counting-based detector. The effect of mismatched signal shapes is also investigated.
Some physical properties of multilayered films (1969)

Abstract Some properties of multilayered films are summarized in relation to the properties of the component materials. Polymers may be selected for co‐extrusion into layered films to obtain various combinations of properties, such as barrier, stiffness, heat sealability, optics, and toughness. Properly chosen combinations of high and low modulus materials exhibit mutual interlayer reinforcement. Permeabilities of multilayer films can be calculated from layer geometry and individual component properties.
TinkerNet: a low-cost networking laboratory (2004)

The 2002 SIGCOMM Workshop on Educational Challenges for Computer Networking [Kur02a] exposed many issues related to teaching computer networking with the need for a laboratory in parallel with lecture a recurring theme. We have created TinkerNet, a low cost (mostly throw-away PCs), laboratory environment for networking experiments focused on the Build-Your-Own-Stack (BYOS) activity. This paper describes the hardware and software environment that is TinkerNet together with a set of student experiments. We discuss our plans for formal assessment to determine how the addition of laboratory experiments affects student learning. Finally the status and availability of TinkerNet is noted.
Longitudinal Stability of Coagulation, Fibrinolysis, and Inflammation Factors in Stored Plasma Samples (2001)

Summary We sought to assess the longitudinal stability of risk factors for atherosclerosis and thrombosis, including several coagulation, fibrinolysis, and inflammation factors, in frozen plasma samples stored at –70° C for months or years. We reviewed data collected on 29 different control pools over periods ranging from 7 to 59 months for two functional assays (factor VII and fibrinogen) and seven antigen measurements (C-reactive protein, D-dimer, plasmin-α 2-antiplasmin complex, plasminogen activator inhibitor-1, protein C, protein S, and tissue plasminogen activator), totaling more than 15,000 data points. Screening of the data using least squares regression revealed only sporadic associations between monthly means and time, with no consistent trends. Analysis by repeated measures and summary measure methods revealed no evidence of sample degradation over time for the factors studied. Our finding of longitudinal stability in the biochemical properties of frozen plasma strengthens the presumption of sample stability on which molecular epidemiologic studies are based.
FINAL RESULTS OBTAINED IN THE SETTING UP OF THE MOLECULAR GUN (1961)

Contents: Ion gun Modifications to the ion accelerator Production of charge or momentum exchanges be tween the high speed ions and the molecules Detection and measurement of the speeds of the high speed molecules Final modifications to the body of the apparatus
Radon anomalies in soil gas caused by seismic activity (2004)

At the Orlica fault in the Krško basin, combined barasol detectors were buried in six boreholes, two along the fault itself and four on either side of it, to measure and record radon activity, temperature and pressure in soil gas every 60 minutes for four years. Data collected have been anal-ysed in a manner aimed at distinguishing radon anoma-lies resulting from environmental parameters (air and soil temperature, barometric pressure, rainfall) from those caused solely by seismic events. The following approaches have been used to identify anomalies: (i) ± 2σ deviation of radon concentration from the seasonal average, (ii) corre-lation between time gradients of radon concentration and barometric pressure, and (iii) prediction with regression trees within a machine learning program. In this paper the results obtained with regression trees are presented. A model has been built in which the program was taught to predict radon concentration from the data collected during the seismically inactive periods when radon is presumably influenced only by environmental parameters. A correlation coefficient of 0.83 between measured and predicted values was obtained. Then, the whole data time series was included and a significantly lowered correlation was observed during the seismically active periods. This reduced correlation is thus an indicator of seismic effect.
Uncertainty of Videogrammetric Techniques used for Aerodynamic Testing (2002)

The uncertainty of videogrammetric techniques used for the measurement of static aeroelastic wind tunnel model deformation and wind tunnel model pitch angle is discussed. Sensitivity analyses and geometrical considerations of uncertainty are augmented by analyses of experimental data in which videogrammetric angle measurements were taken simultaneously with precision servo accelerometers corrected for dynamics. An analysis of variance (ANOVA) to examine error dependence on angle of attack, sensor used (inertial or optical). and on tunnel state variables such as Mach number is presented. Experimental comparisons with a high-accuracy indexing table are presented. Small roll angles are found to introduce a zero-shift in the measured angles. It is shown experimentally that. provided the proper constraints necessary for a solution are met, a single- camera solution can he comparable to a 2-camera intersection result. The relative immunity of optical techniques to dynamics is illustrated.
Modal parameter identification of civil engineering structures under operational conditions (2011)

This paper deals with the realization of finite dimensional, linear, time-invariant models of structural systems in the state space description from the response (output) of the system. The theory and and underlying principles of two stochastic system identification algorithms are first described. The applications of the algorithms to two civil engineering structures follow the theory. Ambient vibration data collected from a building and a bridge, both are permanently instrumented by accelerometer networks, are used to derive the models. The vibration characteristics, i.e., the frequencies, damping ratios, and associated mode shapes, of the structures are then retrieved from the models. The stochastic system identification algorithms prove to be very effective in identifying the vibration characteristics of the structures.
PhySoc Outreach Grant: Reading Science Slam (2014)

In depth Imaging tools and freebiesUnbeknownst to many there is a veritable treasure trove of free online resources and tools for those who engage in biological imaging.The list below is hardly exhaustive, but I've endeavoured to share with you the ones that I've found most useful in my own work, and that will hopefully save you both time and money! Fluorescence Spectraviewer & Stain Your Own Cellwww.lifetechnologies.com/uk/en/home/support/research-tools.htmlTwo extremely useful tools to help with experimental design are offered free online with Invitrogen (Life Technologies).The Fluorescence SpectraViewer allows you to check compatibility of your fluorescent dyes with one another to prevent potential overlap and bleed through.You can also determine what dyes may be suitable for your imaging set-up with the excitation/emission settings.The cell stainer is great for getting an idea of what subcellular structures you may want to counterstain and informs you what reagents are suitable for live or fixed cell purposes.
Colloidal Quantum Dots: Light-Emitting Diodes, Ligands, and Lifetimes (2006)

We describe multilayer hybrid organic/inorganic colloidal quantum dot light-emitting diodes with narrow electroluminescence spectra and good efficiencies at display brightness. We discuss the role of device structure and quantum dot surfactants on device performance. Article not available.
An odyssey in the space of molecules, genes, biology and brain: an interview with Sabine Cordes (2015)

Sabine Cordes is currently Senior Investigator at the Lunenfeld-Tanenbaum Research Institute, where she studies the genes involved in craniofacial and neuronal development and psychiatric disorders. Although now renowned as an excellent mouse geneticist and neurobiologist, she is actually a biochemist by training. Indeed, she started her career at the Department of Biochemistry at Berkeley, University of California, studying ethylene-induced gene expression during tomato fruit ripening with Robert L. Fischer. She then became fascinated by brain development and decided to join Greg Barsh’s lab at Stanford University to work specifically on hindbrain segmentation. Her interest in psychiatric disorders was, in her own words, ‘accidental’. In this interview, Sabine recounts the interesting steps that took her from the study of chemistry and molecules to that of genes and mouse genetics, to researching on neurodevelopment and mood disorders. She also shares with us her personal forward-looking view of biomedical science, based on her own experience and on the impact of new advances that are revolutionising our understanding of cell biology and neurobiology.
Fingerprint-based detection of acute aquatic toxicity (2010)

DOAJ is a unique and extensive index of diverse open access journals from around the world, driven by a growing community, committed to ensuring quality content is freely available online for everyone.
TRPA1 Is a Component of the Nociceptive Response to CO <sub>2</sub> (2010)

In humans, high concentrations of CO(2), as found in carbonated beverages, evoke a mixture of sensations that include a stinging or pungent quality. The stinging sensation is thought to originate with the activation of nociceptors, which innervate the respiratory, nasal, and oral epithelia. The molecular basis for this sensation is unknown. Here we show that CO(2) specifically activates a subpopulation of trigeminal neurons that express TRPA1, a mustard oil- and cinnamaldehyde-sensitive channel, and that these responses are dependent on a functional TRPA1 gene. TRPA1 is sufficient to mediate responses to CO(2) as TRPA1 channels expressed in HEK-293 cells, but not TRPV1 channels, were activated by bath-applied CO(2). CO(2) can diffuse into cells and produce intracellular acidification, which could gate TRPA1 channels. Consistent with this mechanism, TRPA1 channels in excised patches were activated in a dose-dependent manner by intracellular protons. We conclude that TRPA1, by sensing intracellular acidification, constitutes an important component of the nociceptive response to CO(2).
Thermoluminescence and photoluminescence characteristics of nanocrystalline LiNaSO<sub>4</sub> : Eu phosphor (2003)

Europium doped LiNaSO4 in its nanocrystalline form has been prepared and its thermoluminescence (TL) properties are studied. The TL glow curve of the phosphor has been found to have a simple structure with a single peak at 432 K. Though the highly sensitive, commercially available TL phosphor LiF : Mg, Cu, P (TLD-700H) is about 1.5 times more sensitive than the nanocrystalline material, the sensitivity of the concerned nanomaterial is much higher (∼10 times) than the other standard phosphor TLD-100 (LiF : Mg, Ti). Compared to the conventional LiNaSO4 : Eu phosphor (prepared through a melting procedure and having particle size of 125 µm), the nano-sized phosphor has a lesser TL sensitivity. However, this reduction in TL sensitivity on decreasing the particle size from micrometres to nanometres gives a better understanding of the TL phenomenon. The order of TL kinetics for the concerned nanomaterial is also found to be different from that of the conventional material. Photoluminescence studies that have been performed on these materials throw light on the reasons for such a change in the order of kinetics. Further, fading and reusability of the concerned nanomaterial has also been studied and it has been found that the phosphor is quite suitable for radiation dosimetry.
Oscillation of bundle conductors in overhead lines due to turbulent wind (1990)

An analytical methodology to simulate the dynamic behavior of bundle conductors in a turbulent flow is presented. The experimental methodology used in examining the oscillatory behavior of triple-bundled conductors in an operating transmission line is described, and the mathematical model used to predict oscillation amplitudes by comparing the theoretical with the experimental results is validated. The analytical methodology can be used to analyze ice galloping for any kind of bundle, provided the aerodynamic coefficients relevant to the particular ice profiles are known. The results obtained during experiments carried out on a span of an energized 420 kV line equipped with triple bundles and subjected to oscillations due to buffeting are given. The experimental data are compared with the analytical results and satisfactory agreement is obtained.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
The Relationship between the Visual Analog Pain Intensity and Pain Relief Scale Changes during Analgesic Drug Studies in Chronic Pain Patients  (1999)

The relationship between visual analog pain intensity and pain relief scores changed systematically during both analgesic drug studies. The authors hypothesize that patients' interpretation of the pain relief scale had changed during the studies and therefore suggest using the pain intensity scale to quantify analgesic drug action over time.
Thyroid autoimmunity and neuropsychological development. (1992)

Thyroid autoimmunity may affect neuropsychological development by interfering with the fetal and/or neonatal thyroid status; indeed, both hypo- and hyperthyroidism during the fetal-neonatal life may be associated with a subsequent impairment of intellectual and psychomotor performances. Maternal thyroid status during early pregnancy, and in particular hypothyroidism due to autoimmune thyroiditis, can also affect the fetal neurological development. Finally, anti-thyroid drugs used to control hyperthyroidism in pregnant women with Graves' disease have been widely investigated for their possible effect on the intellectual development of the offspring.
Two-Dimensional Electrophoresis and Western-Blotting Analyses with anti Ara h 3 Basic Subunit IgG Evidence the Cross-Reacting Polypeptides of<i>Arachis hypogaea</i>,<i>Glycine max,</i>and<i>Lupinus albus</i>Seed Proteomes (2005)

The allergenicity of seed storage proteins, the major components of edible legume seeds, may cause serious reactions in both children and adult population. Updated methodologies for evaluation of the activity of these proteins are needed. In this paper we used two-dimensional (2D) electrophoretic techniques to investigate the immuno-cross-reactivities of anti Ara h 3 basic subunit IgG to the seed proteomes of three legume species, namely, peanut, soybean, and lupin. The seed proteins, extracted with two different procedures, were separated by 2D electrophoresis, and the electrophoretic maps were analyzed by Western blot. In peanut proteome the antibodies strongly reacted with the 23 kDa polypeptides, corresponding to Ara h 3 basic isoforms, the antigen they were raised to, and three unidentified acidic polypeptides near 45 kDa. Remarkable cross-reactivities with lupin and soybean Ara h 3 homologous polypeptides and nonrelated proteins, namely, lupin conglutin gamma and soybean Bg7S, were detected. Therefore, these proteins may be regarded as new putative allergens. The present findings show the potentiality of 2D electrophoresis in the identification of food allergens and open the way to the traceability of the new cross-reacting proteins in the food chain.
ChemInform Abstract: Ni(II)‐Catalyzed Reactions of Free D‐Fructose Derivatives Modified at Positions C‐5 and/or C‐6. (1999)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Isolation and Culture of Rhesus Adipose-Derived Stem Cells (2010)

Adipose tissue is as an abundant and accessible source of stem cells with multipotent properties suitable for tissue engineering and regenerative medical applications. Rhesus monkeys are physiologically and phylogenetically similar to humans, and they and their cells are valuable for biomedical research and evaluation of preclinical therapies. Here, we describe methods for the isolation, culture, and differentiation of rhesus adipose-derived stem cells (rASCs).
Advanced metamorphosis based on bounded space-time blending (2004)

We further develop a new approach to shape metamorphosis using bounded blending operations in space-time. The key steps of the metamorphosis algorithm are: dimension increase by converting two input kD shapes into half-cylinders in (k+1)D space-time, applying bounded blending union with added material to the half-cylinders, and making cross-sections for getting intermediate shapes under the transformation. This approach is extended here in two directions. First, the problem of "jump" in animation or the rapid transition between shapes in the given interval is solved using "smoothed" versions of half-cylinders which undergo bounded blending. Second, the approach is extended to 3D initial and final shapes with the bounded blending union operation applied to the corresponding "smoothed" 4D space-time half-cylinders.
Studies on Lignin (1959)

Coniferyl alcohol, 1-(4-hydroxy-3-methoxyphenyl)-propanediol-(1, 3) and 1-(4-hydroxy-3-methoxyphenyl)-propanediol-(1, 2) have been found to react with hydrogen sulfide. From the results of paper chromatography and U. V. spectra a portion of the sulfidation products obtained from the first and second compounds appear to be identical. Upon alkali treatment, these products readily yielded a double bond conjugated to aromatic nucleus. From the last-named compound, a crystalline compound was obtained and its structure is discussed here. In accordance with previous works, it was found that symplocosigenol and dehydrodi-isoeugenol do not react with hydrogen sulfide.
A Neurohumoral Mechanism of Reticulo-Cortical Activation (1956)

Cross-perfusion experiments were performed on unanesthetized intact and ‘encephale isole’ cats paralyzed with minimal amounts of succinylcholine-chloride. Stimulation of the bulbar reticular formation in one animal (donor) produced electrocortical ‘activation’ in the second (recipient) animal after 30–80 seconds. In addition to evoking typical activation patterns in the recipient animal, both facilitation and inhibition of Metrazol spikes were obtained in the recipient animal by reticular stimulation of the donor. This effect on the brain of the recipient animal is attributed to the release of a humoral agent from the brain of the first, electrically stimulated (donor) animal. The long latency effect is believed to represent elaboration of the neurohumor through intermediate stages.