gebhart/patrepeval huggingface dataset:
Percutaneous Spinal Fixation Simulation With Virtual Reality and Haptics (2012)

The experiments showed evidence (P = .04) of performance accuracy improvement from the first to the second percutaneous needle placement attempt. This result, combined with previous learning retention and/or face validity results of using the simulator for open thoracic pedicle screw placement and ventriculostomy catheter placement, supports the efficacy of augmented reality and haptics simulation as a learning tool.
How the Structure of the Sarcoplasmic Reticulum Regulates the Accumulation of Calcium (1976)

Conference Article| August 01 1976 How the Structure of the Sarcoplasmic Reticulum Regulates the Accumulation of Calcium G. WARREN; G. WARREN 1Department of Biochemistry, University of Cambridge, Tennis Court Road, Cambridge CB2 1QW, U.K. Search for other works by this author on: This Site PubMed Google Scholar J. C. METCALFE J. C. METCALFE 2Department of Biochemistry, University of Cambridge, Tennis Court Road, Cambridge CB2 1QW, U.K. Search for other works by this author on: This Site PubMed Google Scholar Biochem Soc Trans (1976) 4 (4): 561. https://doi.org/10.1042/bst0040561 Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter LinkedIn Cite Icon Cite Get Permissions Citation G. WARREN, J. C. METCALFE; How the Structure of the Sarcoplasmic Reticulum Regulates the Accumulation of Calcium. Biochem Soc Trans 1 August 1976; 4 (4): 561. doi: https://doi.org/10.1042/bst0040561 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsBiochemical Society Transactions Search Advanced Search This content is only available as a PDF. © 1976 Biochemical Society1976 Article PDF first page preview Close Modal You do not currently have access to this content.
Ulcer associated cell lineage glands expressing trefoil peptide genes are induced by chronic ulceration in ileal pouch mucosa (2001)

UACL glands arise de novo in ileal pouch mucosa of patients with pouchitis and express all three TFF peptide genes. Chronic inflammation alone, present in healthy pouches, is not enough to stimulate the growth of the UACL, and additional stimuli consequent on ulceration may be needed.
Recent Patents on Polymeric Scaffolds for Tissue Engineering (2009)

The past several decades have seen explosive growth in the reports of tissue engineering for tissue repair. All scaffolds of tissue engineering are made of special materials, known as biomaterials, which have been defined as “materials intended to interface with biological systems to evaluate, treat, augment or replace any tissue, organ, or function of the body” [D.F. Williams, The Williams Dictionary of Biomaterials, Liverpool University Press, Liverpool, 1999]. The present article discusses the useful patents in the field of the polymeric biomaterials that are currently developed as scaffolds with their intrinsic physicochemical and dimensional properties for the application towards recent therapeutic strategies for tissue engineering including soft and hard tissue engineering. Keywords: Polymer, scaffold, tissue engineering, tissue regeneration
Guest Editorial (2009)

The 19 papers in this special issue focus on the challenges in the RFID domain and present a broad overview of the state-of-the-art.
A Compendious Urdu Dictionary (1937)

An abstract is not available for this content so a preview has been provided. Please use the Get access link above for information on how to access this content.
Intermediate state polarization in multiphoton ionization of HCl (2006)

The paper presents the detailed theoretical description of the intermediate state polarization and photofragment angular distribution in resonance enhanced multiphoton ionization (REMPI) of molecules and the experimental investigation of these effects in the E(1)Sigma(+) and V(1)Sigma(+) states of HCl populated by two-photon transitions. It is shown that the intermediate state polarization can be characterized by the universal parameter b which is in general a complex number containing information about the symmetry of the two-photon excitation and possible phase shifts. The photofragment angular distribution produced by one- or multiphoton excitation of the polarized intermediate state is presented as a product of the intermediate state axis spatial distribution and the angular distribution of the photofragments from an unpolarized intermediate state. Experiments have been carried out by two complementary methods: REMPI absorption spectroscopy of rotationally resolved (E,v'=0<--X,v"=0) and (V,v'=12<--X,v"=0) transitions and REMPI via the Q(0) and Q(1) rotational transitions followed by three-dimensional ion imaging detection. The values of the parameter b determined from experiment manifest the mostly perpendicular nature of the initial two-photon transition. The experimentally obtained H(+) -ion fragment angular distributions produced via the Q(1) rotational transition show good agreement with theoretical prediction.
Chemical Purity Analysis of PET Radiotracers via Microchip Capillary Electrophoresis (2016)

Production of a positron emission tomography (PET) tracer involves three stages: production of the radioisotope, radio-labeling and purification of the tracer, and quality control (QC) testing of the final product (if the tracer is used in humans). Though the production of the positron-emitting radioisotope requires expensive and complex instrumentation (e.g. cyclotron or generator), in many cases, the radioisotope can simply be obtained from a commercial source. The radio-labeling and purification step is performed by machines called radiosynthesizers, which perform chemical synthesis and purification processes in a remote-controlled or automated manner within radiation-shielded âhot cellsâ. Quality control testing is performed to ensure each batch of radiopharmaceutical is safe prior to use in human subjects, and requires several analytical chemistry instruments. Though a couple of PET tracers are routinely available in final form from commercial sources, most other tracers need to be specially manufactured and quality tested at the researcherâs facility.Advances in radiosynthesizer technology such as automation, programmability, and reagent kits simplify the production of diverse tracers. Furthermore, recent efforts in miniaturized synthesizers based on microfluidics aim to reduce equipment cost, shielding and lab space needs, and quantities of expensive reagents, to make it more affordable to produce custom batches of PET tracers on demand.In the context of these emerging technologies, quality control testing still remains a bottleneck due to the high cost of the many expensive instruments, specially-trained staff, and documentation needed to determine the purity and ensure the levels of all potential contaminants are below acceptable limits. Several companies are developing automated systems for quality control testing to alleviate some of these issues. However, high cost and large size remain obstacles. We have therefore explored the use of microfluidic analytical chemistry techniques to address these remaining critical issues. In this dissertation, the feasibility of using capillary electrophoresis (CE) to analyze the chemical purity of PET tracers is investigated as a compact and inexpensive replacement for high performance liquid chromatography (HPLC) and other techniques that are normally used for this purpose. After establishing that CE has sufficient performance (comparable to HPLC) using several example chemical systems, the design, development, and characterization of a microscale chemical purity testing system are presented, along with a discussion of its capabilities and limitations. Overall, it appears that microchip CE could be used instead of HPLC for performing many of the required QC tests of PET tracers.
MIMO Multiple Access Channel with an Arbitrarily Varying Eavesdropper (2012)

A two-transmitter Gaussian multiple access wiretap channel with multiple antennas at each of the nodes is investigated. The channel matrices at the legitimate terminals are fixed and revealed to all the terminals, whereas the channel matrix of the eavesdropper is arbitrarily varying and only known to the eavesdropper. The secrecy degrees of freedom (s.d.o.f.) region under a strong secrecy constraint is characterized. A transmission scheme that orthogonalizes the transmit signals of the two users at the intended receiver and uses a single-user wiretap code is shown to be sufficient to achieve the s.d.o.f. region. The converse involves establishing an upper bound on a weighted-sum-rate expression. This is accomplished by using induction, where at each step one combines the secrecy and multiple-access constraints associated with an adversary eavesdropping a carefully selected group of sub-channels.
Note Concerning Multiple Reflections within Absorbing Thin Films (1956)

It is shown that the generalized multiple beam model as it is currently formulated breaks down under certain conditions when dealing with multilayer film combinations containing absorbing elements. An example is given by way of illustration.
Resolving power of laser lithography on thin metal films (1984)

A theoretical analysis is made of the resolving power of laser thermolithography under destructive and nondestructive interaction conditions. It is shown that the maximum resolving power of laser lithography in the case of nondestructive interaction corresponds to the resolving power of the optical system employed, whereas in the case of destructive interaction it is governed by the properties of film and substrate materials, by the film thickness, and by the irradiation regime. The conditions ensuring maximal resolving power of laser thermolithography are determined.
Synthesis of [5-Isoleucine,8-alanine]-angiotensin II by the Solution Method Synthesis and the Solid-Phase Method Synthesis<sup>*</sup> (1967)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSynthesis of [5-Isoleucine,8-alanine]-angiotensin II by the Solution Method Synthesis and the Solid-Phase Method Synthesis*Won Kil Park, Robert R. Smeby, and F. Merlin BumpusCite this: Biochemistry 1967, 6, 11, 3458–3464Publication Date (Print):November 1, 1967Publication History Published online1 May 2002Published inissue 1 November 1967https://pubs.acs.org/doi/10.1021/bi00863a016https://doi.org/10.1021/bi00863a016research-articleACS PublicationsRequest reuse permissionsArticle Views32Altmetric-Citations20LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
The crystal structure of SrCl<sub>2</sub> and BaCl<sub>2</sub> hemihydrates by powder diffraction (1994)

Abstract The crystal structures of isomorphous SrCl 2 and BaCl 2 hemihydrates were solved by powder diffraction method. Strontium and barium atoms are coordinated either by nine chloride atoms or by seven chloride and two oxygen atoms. Space group: Pmmn(59), lattice parameters: a ‐ 15.976(1), b ‐ 4.260(5), c ‐ 8.090(1) and a ‐ 16.477(5), b ‐ 4.555(1), c ‐ 8.330(3) Å, for strontium and barium compound, respectively. Rietveld refinement results in the discrepancy factors R B ‐ 10.85, R wp ‐ 12.71% and R B ‐ 4.50% for SrCl 2 and BaCl 2 hemihydrate, respectively.
Control of the p53-p21CIP1 Axis by E2f1, E2f2, and E2f3 Is Essential for G1/S Progression and Cellular Transformation (2006)

The E2F family of transcription factors is believed to have an essential role in the control of cellular proliferation by regulating the transcription of genes involved in cell cycle progression. Previous work has demonstrated that the targeted inactivation of E2f1, E2f2, and E2f3 results in elevated p21(CIP1) protein levels, loss of E2F target gene expression, and cell cycle arrest at G1/S and G2/M, suggesting a strict requirement for these E2Fs in the control of normal cellular proliferation. We now demonstrate that E2f1, E2f2, and E2f3 are also required for oncogene-mediated transformation of mouse embryonic fibroblasts. Analysis of synchronized populations of mouse embryonic fibroblasts revealed that the inactivation of p21(CIP1) restores the ability of E2f1-3-deficient cells to enter and transit through G1/S (but not G2/M). In contrast, loss of p53 restored the ability of these cells to progress through both G1/S and mitosis, leading to their continued proliferation. The inactivation of p53 (but not p21(CIP1)) rendered E2f1-3-deficient cells sensitive to transformation and tumorigenesis. These results suggest that the negative regulation of the p53-p21(CIP1) axis by the E2F1-3 factors is critical for cell cycle progression and cellular transformation.
A new approach for the regiospecific annelation of butenolides (1984)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTA new approach for the regiospecific annelation of butenolidesAede De Groot and Ben J. M. JansenCite this: J. Org. Chem. 1984, 49, 11, 2034–2035Publication Date (Print):June 1, 1984Publication History Published online1 May 2002Published inissue 1 June 1984https://pubs.acs.org/doi/10.1021/jo00185a047https://doi.org/10.1021/jo00185a047research-articleACS PublicationsRequest reuse permissionsArticle Views174Altmetric-Citations22LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Editor's Comments (1994)

An abstract is not available for this content so a preview has been provided. As you have access to this content, a full PDF is available via the ‘Save PDF’ action button.
Numerical analysis of the effect of nitrogen and oxygen admixtures on the chemistry of an argon plasma jet operating at atmospheric pressure (2015)

ABSTRACT: In this paper we study the cold atmospheric pressure plasma jet, called kinpen, operating in Ar with different admixture fractions up to 1% pure ${{{\rm N}}_{2}}$, ${{{\rm O}}_{2}}$ and ${{{\rm N}}_{2}}$ + ${{{\rm O}}_{2}}$. Moreover, the device is operating with a gas curtain of dry air. The absolute net production rates of the biologically active ozone (${{{\rm O}}_{3}}$) and nitrogen dioxide (${\rm N}{{{\rm O}}_{2}}$) species are measured in the far effluent by quantum cascade laser absorption spectroscopy in the mid-infrared. Additionally, a zero-dimensional semi-empirical reaction kinetics model is used to calculate the net production rates of these reactive molecules, which are compared to the experimental data. The latter model is applied throughout the entire plasma jet, starting already within the device itself. Very good qualitative and even quantitative agreement between the calculated and measured data is demonstrated. The numerical model thus yields very useful information about the chemical pathways of both the ${{{\rm O}}_{3}}$ and the ${\rm N}{{{\rm O}}_{2}}$ generation. It is shown that the production of these species can be manipulated by up to one order of magnitude by varying the amount of admixture or the admixture type, since this affects the electron kinetics significantly at these low concentration levels.
Efficient learning from adaptive control under sufficient excitation (2019)

Summary Parameter convergence is desirable in adaptive control as it enhances the overall stability and robustness properties of the closed‐loop system. In existing online historical data (OHD)–driven parameter learning schemes, all OHD are exploited to update parameter estimates such that parameter convergence is guaranteed under a sufficient excitation (SE) condition which is strictly weaker than the classical persistent excitation condition. Nevertheless, the exploitation of all OHD not only results in possible unbounded adaptation but also loses the flexibility of handling slowly time‐varying uncertainties. This paper presents an efficient OHD‐driven parameter learning scheme for adaptive control, where a variable forgetting factor is specifically designed and is equipped with an estimation error feedback such that exponential parameter convergence is achieved under the SE condition without the aforesaid drawbacks. The proposed parameter learning scheme is incorporated with direct adaptive control to construct an OHD‐based composite learning control strategy. Numerical results have verified the effectiveness of the proposed approach.
Development of Water Quenching Technique for Cold Rolled Steel Strip (1976)

The cause of deterioration in strip shape in the course of water quenching has been made clear, and the water quenching technique for steel strip has been developed. The deterioration of strip shape results from the uneven disappearing (particularly from the edge of strip) of vapour film on strip surface. In order to improve the shape, it is necessary to quench the strip under such a condition that vapour film is not formed. This condition can be realized by spraying water to the strip uniformly with the impinging pressure of over 15 cm aq. until the strip is cooled below the transition temperature from film boiling to nucleate boiling. This condition of jet stream of water can be industrialized by means of an appropriate arrangement of slit nozzles and the suitable control of water pressure in headers. The most important point in the nozzle arrangement is to make the intervals between nozzles less than those between nozzle plates and strip. The shape of quenched sheet can be improved to the same level as that of shipped cold rolled sheet through the appropriate control of quenching conditions.
Interfacial phenomena in enhanced oil recovery (1982)

The aspects of interfacial phenomena important to tertiary oil recovery discussed include fundamental aspects of the oil displacement processes, interfacial properties and phase behavior, fluid microstructures, petroleum component properties, dynamic phenomena including droplet coalescence and entrapment processes, surfactant precipitation and redissolution, flow through porous media, and inaccessible pore volume and slip phenomena in polymer flow.
4-Piperidones from Enantiomerically Pure Enones. Synthesis of 6-alkylsubstituted 4-oxo-pipecolic acid derivatives (1998)

The cyclization of the enantiomerically pure α,β-unsaturated ketone 1, an aliphatic aldehyde 3 and ammonia or benzylamine gives diastereoselectively cis-piperidones 4/4′. Although only modest yields were obtained, the presented cyclization has the advantage of being a single step reaction. The products 4 can serve as precursors for all-cis-4-hydroxy-piperidones 5 and novel pipecolic acid derivates 9.
Human Monoclonal Antibodies against Highly Conserved HR1 and HR2 Domains of the SARS-CoV Spike Protein Are More Broadly Neutralizing (2012)

Immune sera from convalescent patients have been shown to be effective in the treatment of patients infected with Severe Acute Respiratory Syndrome Virus (SARS-CoV) making passive immune therapy with human monoclonal antibodies an attractive treatment strategy for SARS. Previously, using Xenomouse (Amgen British Columbia Inc), we produced a panel of neutralizing Human monoclonal antibodies (HmAbs) that could specifically bind to the ectodomain of the SARS-CoV spike (S) glycoprotein. Some of the HmAbs were S1 domain specific, while some were not. In this study, we describe non-S1 binding neutralizing HmAbs that can specifically bind to the conserved S2 domain of the S protein. However, unlike the S1 specific HmAbs, the S2 specific HmAbs can neutralize pseudotyped viruses expressing different S proteins containing receptor binding domain sequences of various clinical isolates. These data indicate that HmAbs which bind to conserved regions of the S protein are more suitable for conferring protection against a wide range of SARS-CoV variants and have implications for generating therapeutic antibodies or subunit vaccines against other enveloped viruses.
Novel Sulfinyl Imine Ligands for Asymmetric Catalysis (2003)

[structure: see text] A novel class of P,N-sulfinyl imine ligands has been prepared that incorporates chirality solely at sulfur. The Pd complex of ligand 14 catalyzes the allylic alkylation reaction with high enantioselectivity (94%), and the first crystal structure of a Pd-bound sulfinyl imine provides insight into binding mode and origins of stereoselectivity.
Direct Measurements of Deuterium Kinetic Isotope Effects in Anionic, Gas-Phase Substitution and Elimination Reactions (2007)

Reactions with dianion nucleophiles were used to determine deuterium kinetic isotope effects (KIE's) in gas-phase E2 and SN2 reactions. This approach allows for the direct identification of elimination and substitution products in the reactions of simple alkyl halides. In general, the E2 reactions give large KIE's (∼7) for perdeutero substrates; however, elimination isotope effects are attenuated in reactions that occur near the collision-controlled limit. In a very slow elimination, a large KIE (>20) is observed, presumably due to lifetime effects in the collision complex. The SN2 reactions all give secondary deuterium isotope effects near unity, with the exception of one system, where suppression of the E2 channel in the perdeutero substrate leads to an enhancement of the SN2 rate and causes a modest inverse isotope effect.
Improvement in Rod-Pinch Diode Performance With Anode Heating (2002)

We have studied the performance of rod‐pinch diodes with heated anodes. Anode heating is seen to virtually eliminate the proton component of the ion beam, leading to an increase in radiation efficiency. With heated anodes the beam pinches slightly closer to the rod tip which leads to a reduction in spot size when tapered anodes are used. An expected reduction in the rate of impedance collapse is not observed. Heating is easy to implement, and the observed improvements in diode performance merit further study of this approach.