gebhart/patrepeval huggingface dataset:
Effect of pressure on the crystallization of polyethylene (1973)

Abstract Crystallization of polyethylene under pressure has been studied systematically with regard to the structure of the resultant crystal. It was found that in the isothermal crystallization under pressure, alteration of the form of the crystals from folded to extended occurred above certain pressures within a relatively narrow temperature range. The highest temperature that allows isothermal crystallization increases linearly with the pressure, while the lowest temperature to give the extended‐chain crystals increases rather slowly with pressure, widening the temperature range to give the extended‐chain crystals. The least pressure required was found between 2000 and 3000 kg/cm 2 for the polymer studied in this work. It is considered that control by a particular nucleation or growth mechanism, different from the ordinary folded‐chain type crystallization and possibly the formation of bundle‐type nucleus is more likely than the effect of annealing or secondary growth of once folded molecules.
Quest and Evaluation of Topcoat Materials for Environmental Barrier Coatings of SiC/SiC Composites (2006)

SiC fiber reinforced SiC matrix (SiC/SiC) composites are one of the most promising materials for high temperature structural applications such as power generation and propulsion systems. SiC/SiC composites are, however, susceptible to accelerated attacks in water vapor environments through oxidation and volatilization reaction. For protection from such attacks, Environmental Barrier Coatings (EBCs) are indispensable. We have investigated some oxides and rare-earth silicates as topcoat candidate materials for EBCs. Topcoat materials must be stable in the high-water-vapor pressurized environments at high temperatures. Also, it is important that the thermal expansion coefficient of topcoat materials is similar to that of the SiC/SiC composites. In this study, first, zirconium oxides, lutetium silicates and yttrium silicates were selected as topcoat candidate materials. They were exposed in a water-containing atmosphere at a temperature of 1673 K for 100 h under a total pressure 0.96 MPa. Mass changes, structure of crystals and microstructures were investigated after the exposure experiments in order to evaluate the thermal stability of these materials. After their estimation, lutetium silicates were considered to be promising for topcoat materials. Then, lutetium silicates were coated as the topcoat of an EBC system on SiC/SiC composites, and their fracture toughness and microstructures were investigated after exposure to an oxidizing atmosphere. The evaluation results of the topcoat materials are reported in this paper.
Use of Solvent Effects to Improve Control Over Nitroxide‐Mediated Polymerization of Isoprene (2012)

The use of 1,4-dioxane or pyridine as solvents for the polymerization of isoprene mediated by the acid-functional SG1-based alkoxyamines N-(2-methylpropyl)-N-(1-diethylphosphono-2,2-dimethylpropyl)-O-(2-carboxylprop-2-yl)hydroxylamine (BlocBuilder MA) and N-(2-methylpropyl)-N-(1-diethylphosphono-2,2-dimethylpropyl)-O-(2-carboxyleth-2-yl)hydroxylamine results in an increase in the rate of consumption of the initiator and narrower molecular weight distributions of the resulting polymer. In pyridine, an improved control of the polymerization was also obtained for a non-acid-functional initiator, and the overall rate of polymerization increased. These effects are likely to be the result of the disruption of intramolecular hydrogen bonding and, in the case of pyridine, stabilization of the polar SG1 free radical.
Instruction set selection for ASIP design (2003)

Article Instruction set selection for ASIP design Share on Author: Michael Gschwind IBM Thomas J. Watson Research Center, Yorktown Heights, NY IBM Thomas J. Watson Research Center, Yorktown Heights, NYView Profile Authors Info & Affiliations CODES '99: Proceedings of the seventh international workshop on Hardware/software codesignMarch 1999 Pages 7–11https://doi.org/10.1145/301177.301187Published:01 March 1999 25citation505DownloadsMetricsTotal Citations25Total Downloads505Last 12 Months3Last 6 weeks0 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteGet Access
ART and uterine pathology: how relevant is the maternal side for implantation? (2014)

The real effect of different uterine/endometrial integrity pathologies on ART is not known. Moreover, currently proposed treatments are not based on solid evidence, and little can be done to assess ER in normal or abnormal conditions. No strong recommendations can be given based on the published experience, bringing an urgent need for well-designed studies. In this context, we propose algorithms to study the uterus in ART.
Breakthrough in energy generation for mobile or portable devices (2007)

Portable devices (telephone, GPS, Walkman...) are more and more popular and sophisticated. Thus they require more and more energy for comfortable use of new functionalities (TV on telephones, video on Walkmans). The problem of the too frequent energy recharges of these objects, which make them less and less "nomadic", is then a topical subject. Indeed, the interest of having the video-telephony on the mobile phone becomes very limited since it is necessary to recharge the device more than once per day. We will consequently study what is currently available on the market to provide the required energy, i.e. essentially the batteries. By observing that the batteries do not always constitute a satisfactory response to this problem, in particular from the point of view of their recharge, of their provisioning and, of course, of the environment, it is interesting to look at the most promising alternatives at short or medium term. And finally we propose to analyze the solutions suggested, in terms of use wished by the user.
ChemInform Abstract: Intramolecular (2 + 2) Photocycloaddition. Part 17. Effects of the Linkage Length and Substituents on the Photocycloaddition of Bis( vinylnaphthyl)alkanes Toward Naphthalenophanes. (1993)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Low Overhead Broadcast Encryption from Multilinear Maps. (2014)

We use multilinear maps to provide a solution to the long-standing problem of public-key broadcast encryption where all parameters in the system are small. In our constructions, ciphertext overhead, private key size, and public key size are all poly-logarithmic in the total number of users. The systems are fully secure against any number of colluders. All our systems are based on an O(logN)-way multilinear map to support a broadcast system for N users. We present three constructions based on different types of multilinear maps and providing different security guarantees. Our systems naturally give identity-based broadcast systems with short parameters. 1
Endothelium-dependent relaxation by angiotensin-converting enzyme inhibitors in canine femoral arteries (1994)

The effects of angiotensin-converting enzyme (ACE) inhibitors on vascular reactivity were investigated using isolated canine femoral arteries with and without endothelium. N-N-(S)-1-carboxy-3-phenylpropyl-L-alanyl-N-(indan-2-yl)glycine (M-1; an active metabolite of delapril, a nonsulfhydryl ACE inhibitor) and captopril (a sulfhydryl ACE inhibitor, 10(-8) to 10(-5) M) relaxed in a dose-dependent manner canine femoral arterial rings precontracted with prostaglandin F2 alpha in the presence of endothelium only. The endothelium-dependent relaxations by M-1 and captopril were completely blocked by methylene blue, an inhibitor of soluble guanylate cyclase; NG-monomethyl-L-arginine (L-NMMA), an inhibitor of nitric oxide synthesis; and oxyhemoglobin, an inactivator of nitric oxide; they were partially blocked by aspirin, an inhibitor of cyclooxygenase and were enhanced by superoxide dismutase, a radical scavenger. The inhibitory effect of L-NMMA on the relaxations by M-1 and captopril were reversed by a high dose of L-arginine. Moreover, a bradykinin antagonist partially inhibited these relaxations. These results suggest that endothelium-dependent relaxations by M-1 and captopril in canine femoral arteries are mediated through the release of both prostanoids and endothelium-derived nitric oxide via endogenous bradykinin.
Induction of Apoptosis in B Lineage Cells by Activin A Derived from Macrophages (1995)

A factor produced by P388D1 cell line murine macrophages showed a profound suppressive effect on the in vitro proliferation of B lineage cells. It was purified to homogeneity from conditioned media of P388D1 cells stimulated with phorbol 12-myristate 13-acetate for 48 h by a three-step procedure. The purified factor gave a single band of protein with a molecular mass of 16 kD on SDS-polyacrylamide gel electrophoresis. We show here that exposure of B lineage cells to this factor results in the induction of a cytotoxic effect and a significant increase in the proportion of fragmented DNA. DNA fragmentation was detected in B lineage cells after 3 h culture with the factor in the quantitative colorimetric determination. The mechanism of cell death was characterized by a ladder-like electrophoretic pattern of degraded chromosomal DNA, indicating that the factor induces apoptosis. The NH2-terminal amino acid sequence of this factor was identical with that of activin A over the 26 amino acid residues identified. We sought to determine whether apoptosis could be modulated by two kinds of inhibitor of protein kinases, H7 and HA1004, in concentrations that are below their toxicity limits. Apoptosis induced by the factor was suppressed by H7 but was relatively unaffected by HA1004. These findings suggest that the signals by protein kinases may regulate apoptotic B cell death by the factor activin A, derived from macrophages.
Instability of a plane conducting free surface submitted to an alternating magnetic field (1998)

This paper considers the stability of a horizontal liquid-metal free surface in the presence of a horizontal alternating magnetic field. A weak formulation is used to derive a generalized Mathieu–Hill equation for the evolution of surface perturbations. Previous studies which rely on time-averaging the electromagnetic force over one field cycle have predicted a generally weak instability, but we find much larger growth rates near the resonances, where the surface wave frequency is an integral multiple of the field frequency. The method can be extended to include viscous and ohmic damping; the former has little effect, while the latter damps all waves except those whose frequency is close to the field frequency. Growth rates can be closely approximated by simple algebraic formulae, as can the critical magnetic field strength for the onset of instability.
Viscoelastic effects and anomalous transient levelling exponents in thin films (2014)

International audience
A vitamin D analogue (MC 1288) has immunomodulatory properties and suppresses collagen-induced arthritis (CIA) without causing hypercalcaemia (1998)

The immunomodulatory properties of the vitamin D analogue MC 1288 (20-epi-1alpha,25-dihydroxycholecalciferol) were investigated in CIA in rats. The analogue was administered systemically at three different time points; (i) for 10 consecutive days before collagen (CII) immunization; (ii) for 10 consecutive days after CII immunization; or (iii) for 7 consecutive days from disease onset. Treatment initiated either 10 days before CII immunization or at the day of collagen immunization effectively suppressed the development of arthritis. Treatment initiated at the day of the onset of arthritis reduced the severity of joint inflammation. Significantly, doses which did not induce hypercalcaemia decreased the incidence and severity of arthritis. In vivo treatment with the 20-epi analogue of 1alpha,25-dihydroxycholecalciferol diminished the serum levels of antibodies to rat CII. Similarly, mitogen-induced proliferation of lymph node cells from rat CII-immunized animals was reduced. The experiments demonstrate that the vitamin D analogue MC 1288 has the ability to prevent, and furthermore to suppress, already established CIA by its immunomodulatory properties without inducing hypercalcaemia.
Ultimate Confinement of Phonon Propagation in Silicon Nanocrystalline Structure (2018)

Temperature-dependent thermal conductivity of epitaxial silicon nanocrystalline (SiNC) structures composed of nanometer-sized grains separated by ultrathin silicon-oxide (SiO_{2}) films (∼0.3 nm) is measured by the time domain thermoreflectance technique in the range from 50 to 300 K. The thermal conductivity of SiNC structures with a grain size of 3 and 5 nm is anomalously low at the entire temperature range, significantly below the values of bulk amorphous Si and SiO_{2}. The phonon gas kinetic model, with intrinsic transport properties obtained by first-principles-based anharmonic lattice dynamics and phonon transmittance across ultrathin SiO_{2} films obtained by atomistic Green's function, reproduces the measured thermal conductivity without any fitting parameters. The analysis reveals that mean free paths of acoustic phonons in the SiNC structures are equivalent or even below half the phonon wavelength, i.e., the minimum thermal conductivity scenario. The result demonstrates that the nanostructures with extremely small length scales and a controlled interface can give rise to ultimate classical confinement of thermal phonon propagation.
Using Bessel beams and two-photon absorption to predict radiation effects in microelectronics (2019)

Pulsed-laser testing is an attractive tool for studying space-based radiation effects in microelectronics because it provides a high degree of spatial resolution and is more cost-effective than conventional accelerator-based testing. However, quantitatively predicting the effects of radiation is challenging for this optical method. A new approach to pulsed-laser testing is presented, which addresses these challenges by using a Bessel beam and carrier generation via two-photon absorption. By producing a carrier distribution in the device under test that is similar to that of a heavy ion, this optical approach aims to quantitatively predict the response of the device under heavy ion tests that represent space radiation. Furthermore, the carrier distribution can be accurately described using a single analytic expression thereby enabling the laser to be tuned to emulate a specific heavy ion. Herein, we describe the modifications made to an existing pulsed-laser setup to generate this carrier distribution, characterize this distribution using a novel method that provides sub-micron spatial resolution, and provide the equations that describe the distribution. Finally, we use this method to study a silicon photodiode and find that the transient response of the device shows strong agreement with the response generated using heavy ions.
Nylon cDNA Expression Arrays (2003)

Nucleic acid arrays provide a powerful methodology for studying biological systems on a genomic scale. BD Atlas™ Arrays, developed by BD Biosciences Clontech, are expression profiling products specifically designed to be accessible to all laboratories performing isotopic blot hybridization experiments. We have developed two types of readily accessible BD Atlas Arrays: nylon macroarrays, well suited for high-sensitivity expression profiling using a limited gene set, and broad-coverage plastic microarrays, for a more extensive analysis of a comprehensive set of genes. In this chapter, we describe protocols for printing and performing gene expression analysis using nylon membrane-based arrays. For a more in-depth description and protocols related to plastic film-based arrays, please refer to Chapter 3 .
Drilling Delamination Outcomes on Glass and Sisal Reinforced Plastics (2012)

Nowadays, fibre reinforced plastics are used in a wide variety of applications. Apart from the most known reinforcement fibres, like glass or carbon, natural fibres can be seen as an economical alternative. However, some mistrust is yet limiting the use of such materials, being one of the main reasons the inconsistency normally found in their mechanical properties. It should be noticed that these materials are more used for their low density than for their high stiffness. In this work, two different types of reinforced plates were compared: glass reinforced epoxy plate and sisal reinforced epoxy plate. For material characterization purposes, tensile and flexural tests were carried out. Main properties of both materials, like elastic modulus, tensile strength or flexural modulus, are presented and compared with reference values. Afterwards, plates were drilled under two different feed rates: low and high, with two diverse tools: twist and brad type drill, while cutting speed was kept constant. Thrust forces during drilling were monitored. Then, delamination area around the hole was assessed by using digital images that were processed using a computational platform previously developed. Finally, drilled plates were mechanically tested for bearing and open-hole resistance. Results were compared and correlated with the measured delamination. Conclusions contribute to the understanding of natural fibres reinforced plastics as a substitute to glass fibres reinforced plastics, helping on cost reductions without compromising reliability, as well as the consequence of delamination on mechanical resistance of this type of composites.
Behavior of liquid lithium jet irradiated by 1 MeV electron beams up to 20 kW (2005)

Experiments were conducted to demonstrate the stable operation of the windowless liquid lithium target under extreme thermal loads that are equivalent to uranium beams from the proposed Rare Isotope Accelerator (RIA) driver linac. The cross section of the windowless liquid lithium target was 5mm×10mm and the velocity of the liquid lithium was varied up to 6m∕s. Thermal loads up to 20 kW within a beam spot of 1 mm in diameter were applied on the windowless liquid lithium target by 1 MeV electron beams. The maximum power density and total power deposited within the target was equivalent to that of a 200 kW, 400MeV∕u uranium beam. It was demonstrated that the windowless liquid lithium target flowing at as low as 1.8m∕s stably operates at a beam energy deposition up to 20 kW without disruption or excess vaporization.
Salt‐tolerant <i>Triticum</i>×<i>Lophopyrum</i> derivatives limit the accumulation of sodium and chloride ions under saline‐stress (1989)

Abstract. Cultivars of hexaploid wheat ( Triticum aestivum cvs. Chinese Spring or PI 178704) and derivatives containing chromosomes from both a cultivar and a wild, salt‐tolerant species ( Lophopyrum elongatum or L. ponticum ) were compared to determine differences in growth, ion transport and ion accumulation under salt‐stress. Two experiments were conducted in which plants were grown under saline and non‐saline conditions and harvested at various lime intervals throughout ontogeny. Under salt‐stress the growth rate of the cultivars, as compared to the growth rate of the derivatives, decreased more rapidly later in development. Transport rates from root to shoot of Na + and Cl − reached higher levels in the cultivars. The cultivars accumulated more Na + and Cl − and relatively less K + in the shoot. The K + /Na + ratio was higher in the derivatives than in the cultivars from which they were derived. The addition of chromosomes from Lophopyrum species into wheat altered ion accumulation, growth rates, and ion transport rates from root to shoot.
[OP.5A.08] HCARG/COMMD5 IMPROVES KIDNEY REPAIR BY REGULATING EGF RECEPTOR TRAFFICKING (2017)

Objective: Epidermal Growth Factor Receptor (EGFR) is crucially involved in nephrogenesis. Although, constitutive EGFR signaling is needed for normal kidney development and can enhance recovery of renal function and structure following acute kidney injury, its overexpression may leads to excess renal tissue fibrosis and functional deterioration in diabetic and hypertensive nephropathy. Consequently, targeting EGFR in renal diseases is complex. Our group has identified HCaRG (Hypertension-related, Calcium-Regulated Gene), currently named COMMD5, whose overexpression in an in vivo model of renal carcinoma inhibited tumor growth and angiogenesis by inhibiting EGFR activation and downstream signaling. Overexpression of COMMD5 in renal proximal tubules of transgenic mice increased mice survival and recovery of renal tissue integrity and function after acute kidney injury. Our goal is to demonstrate that COMMD5 accelerated kidney repair by controlling EGFR activity, endocytosis and trafficking. Design and method: COMMD5 was silenced by siRNA and EGFR expression and activation were evaluated in renal cell lines. Intracellular localization of COMMD5, EGFR and endosome associated protein, such as Rab, were analyzed by confocal microscopy and live cell imaging. Co-immunoprecipitations were used to investigate interactions between COMMD5 and proteins known to be involved in vesicle trafficking. Results: We demonstrated that COMMD5 is an adaptor protein forming a bridge between endosomes and cytoskeleton by binding Rab protein and microtubules/actin. This tethering is essential because silencing of COMMD5 delayed the intracellular transport dynamic and consequently cargo protein such as EGFR. Defect in intracellular trafficking led to loss of cell polarity and oriented migration which are crucial for tissue repair. Conclusions: Our results demonstrated that COMMD5 plays a crucial role in controlling EGFR signaling/trafficking and suggest that COMMD5 could be used as a novel target for EGFR-targeted therapy in kidney diseases.