gebhart/patrepeval huggingface dataset:
Evaluation of a self‐administered questionnaire on hand dermatitis (1992)

The purpose of the study was to evaluate a self-administered questionnaire on hand dermatitis that was developed to identify persons with hand dermatitis in epidemiological studies. A total of 109 nurses were subject to dermatological examination of the hands within 1 month of returning the questionnaire. 2 types of questionnaire diagnoses were made: a 'symptom-based' diagnosis and a 'self-reported diagnosis'. These were compared to the medical diagnosis of hand dermatitis. The prevalence of hand dermatitis in the 12 months before the study, based on the medical diagnosis, was 18.3%. The prevalence according to the symptom-based diagnosis and the self-reported diagnosis was 47.7% and 17.4%, respectively. The sensitivity and specificity of the symptom-based diagnosis were 100% and 64%, respectively. It is concluded that the symptom-based diagnosis can be used as screening instrument for the detection of cases in large study populations, if followed by dermatological examination of persons with a positive diagnosis. The sensitivity and specificity of the self-reported diagnosis were 65% and 93%, respectively. It is concluded that the self-reported diagnosis can be used to obtain a rough estimate of the prevalence, although comparison of prevalence figures between study populations may be distorted due to a difference in reporting of hand dermatitis. The results of the study illustrate the size of the differences in prevalence estimates that may arise as a result of differences in the definition and method of diagnosing hand dermatitis.
Intel's secret is out (1989)

The design and development of the million-transistor N10 chip, which is aimed at workstations and supercomputers, is described. This superfast microprocessor is also the company's first chip to use a reduced instruction set. The chip is designed for testability, executes each instruction in one clock cycle, and features on-chip parallelism.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Energy Production Analysis and Optimization of Mini-Grid in Remote Areas: The Case Study of Habaswein, Kenya (2017)

Rural electrification in remote areas of developing countries has several challenges which hinder energy access to the population. For instance, the extension of the national grid to provide electricity in these areas is largely not viable. The Kenyan Government has put a target to achieve universal energy access by the year 2020. To realize this objective, the focus of the program is being shifted to establishing off-grid power stations in rural areas. Among rural areas to be electrified is Habaswein, which is a settlement in Kenya’s northeastern region without connection to the national power grid, and where Kenya Power installed a stand-alone hybrid mini-grid. Based on field observations, power generation data analysis, evaluation of the potential energy resources and simulations, this research intends to evaluate the performance of the Habaswein mini-grid and optimize the existing hybrid generation system to enhance its reliability and reduce the operation costs. The result will be a suggestion of how Kenyan rural areas could be sustainably electrified by using renewable energy based off-grid power stations. It will contribute to bridge the current research gap in this area, and it will be a vital tool to researchers, implementers and the policy makers in energy sector.
Calculation of poissonian fields by means of the method of tubes and slices (1985)

Dual variational principles have been devised to provide a simple and accurate method for the calculation of the energy of Poissonian fields. The method is illustrated by the calculation of the inductance of a T-shaped conductor in a slot with iron boundaries. In comparison with the normal finite-element method, the computing time is reduced by at least an order of magnitude.
Periodic Carbohydrate Replacement during 50 Min of High-Intensity Cycling Improves Subsequent Sprint Performance (1995)

The purpose of this study was to investigate the effect of 7% carbohydrate-electrolyte (CE) drink on sprint capacity immediately following 50 min of high-intensity cycling. After an overnight 12-hr fast, 8 trained male cyclists performed two 50-min simulated time trials on a Monark stationary cycle ergometer. Subjects consumed either the CE or a flavored water placebo (PL) at 10, 20, 30, and 40 min during the time trial. At the conclusion of each 50-min time trial, subjects immediately performed a Wingate Anaerobic Power Test. Peak power, mean power, and minimum power were significantly higher for the CE trials, whereas mean RPE was significantly lower. Mean heart rate and fatigue index were not different between trials. These results suggest that sprint performance following a high-intensity simulated time trial of only 50 min can be improved with periodic consumption of CE during the ride, particularly following an overnight fast, when liver glycogen is likely to be low. These findings have implications for competitive cycling, where sprint capacity at the conclusion of a race is an important determinant of success.
Depolymerization of synovial fluid hyaluronic acid (HA) by the complete myeloperoxidase (MPO) system may involve the formation of a HA-MPO ionic complex. (1990)

Gel filtration analysis (Sephacryl S-1000) indicated that the Mr of purified equine synovial cell culture 3H-hyaluronic acid (HA) (Mr greater than 1.67 x 10(7) Da) decreased in a concentration dependent manner after exposure to hypochlorite (OCl-). Both high (equine) and medium (human, Mr = 5.5 x 10(5) Da) molecular weight HA were cleaved by the complete myeloperoxidase system (MPO/H2O2/Cl-). Purified human neutrophil myeloperoxidase (MPO) bound tightly to HA-Sepharose and we suggest that this is due to a strong ionic interaction between HA and MPO. The formation of such a complex did not disturb MPO activity. The significance of these results in relation to our previous studies concerning the reduction in viscosity and potential cleavage of HA by the product of the MPO/H2O2/Cl- system is discussed.
A Study on the Decontaminated Efficiency of Ultraviolet Device on the Indoor Airborne Bacteria (2017)

The aims of this paper were studied bactericidal effect of the ultraviolet lamp on irradiation intensity, irradiation time and installation height. Three independent variables were set, such as irradiation intensity, irradiation time and installation height. By natural sedimentation method, the airborne bacteria were sampled before and after radiation of ultraviolet lamp, then the decay rates of airborne bacteria were calculated. The decontaminated efficiency were more than 40% when irradiation power of UV were 30w (42.5%) and 40w (60%). With the lengthen irradiation time, the better reduced rate of the airborne bacteria. The bactericidal effect of the ultraviolet lamps was in proportion to their irradiation intensity and in inverse proportion to their installation height. According to the actual circumstance of university cafeteria, the arrangement of ultraviolet lamp was that irradiation intensity was 40W, installation height was 2.0m, and irradiation time was 60min.
Identification of ErbB-2 kinase domain motifs required for geldanamycin-induced degradation. (2003)

The ansamycin antibiotic geldanamycin (GA) induces the intracellular degradation of ErbB-2/neu. Degradation of ErbB-2 proceeds through cleavage(s) within the kinase domain, resulting in the formation of a 135 kDa ectodomain fragment and a fragment(s) of approximately 50 kDa containing the COOH-terminal region. On the basis of independent means of identification, two adjacent sequence motifs have been identified in ErbB-2 that are required for GA-induced degradation. These motifs encompass residues 776-783 and 784-786 within the NH(2)-terminal lobe of the ErbB-2 kinase domain. This is also a region in which the epidermal growth factor receptor and ErbB-2 kinase domains differ significantly in sequence. Although mutations in this region abrogate GA-induced ErbB-2 degradation, the tyrosine kinase activity of ErbB-2 is not disrupted. Interestingly, these ErbB-2 mutants are specifically resistant to GA-induced degradation but retain sensitivity to other drugs, such as staurospore and curcumin, which are also able to provoke ErbB-2 degradation.
Multidrug-Resistant<i>Acinetobacter</i>spp.: Increasingly Problematic Nosocomial Pathogens (2011)

Pathogenic bacteria have increasingly been resisting to antimicrobial therapy. Recently, resistance problem has been relatively much worsened in Gram-negative bacilli. Acinetobacter spp. are typical nosocomial pathogens causing infections and high mortality, almost exclusively in compromised hospital patients. Acinetobacter spp. are intrinsically less susceptible to antibiotics than Enterobacteriaceae, and have propensity to acquire resistance. A surveillance study in Korea in 2009 showed that resistance rates of Acinetobacter spp. were very high: to fluoroquinolone 67%, to amikacin 48%, to ceftazidime 66% and to imipenem 51%. Carbapenem resistance was mostly due to OXA type carbapenemase production in A. baumannii isolates, whereas it was due to metallo-β-lactamase production in non-baumannii Acinetobacter isolates. Colistin-resistant isolates were rare but started to be isolated in Korea. Currently, the infection caused by multidrug-resistant A. baumannii is among the most difficult ones to treat. Analysis at tertiary care hospital in 2010 showed that among the 1,085 isolates of Acinetobacter spp., 14.9% and 41.8% were resistant to seven, and to all eight antimicrobial agents tested, respectively. It is known to be difficult to prevent Acinetobacter spp. infection in hospitalized patients, because the organisms are ubiquitous in hospital environment. Efforts to control resistant bacteria in Korea by hospitals, relevant scientific societies and government agencies have only partially been successful. We need concerted multidisciplinary efforts to preserve the efficacy of currently available antimicrobial agents, by following the principles of antimicrobial stewardship.
Properties of an Expansive Cement for Chemical Prestressing (1961)

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P. Laborde. — Les villes françaises. Bayonne et la région urbaine côtière. (1976)

Robert Jean. P. Laborde. — Les villes françaises. Bayonne et la région urbaine côtière.. In: Norois, n°89, Janvier-Mars 1976. pp. 118-120.
Cytotoxic effects of Coptis chinensis and Epimedium sagittatum extracts and their major constituents (berberine, coptisine and icariin) on hepatoma and leukaemia cell growth (2004)

1. The present study was conducted to evaluate the cytotoxic effects of Coptis chinensis and Epimedium sagittatum extracts and their major constituents on hepatoma and leukaemia cells in vitro. 2. Four human liver cancer cell lines, namely HepG2, Hep3B, SK-Hep1 and PLC/PRF/5, and four leukaemia cell lines, namely K562, U937, P3H1 and Raji, were used in the present study. 3. Of the two crude drugs, C. chinensis exhibited the strongest activity against SK-Hep1 (IC50 = 7 microg/mL) and Raji (IC50 = 4 microg/mL) cell lines. The IC50 values for C. chinensis on HepG2, Hep3B and PLC/PRF/5 cell lines were 20, 55 and 35 microg/mL, respectively. The IC50 values for C. chinensis on K562, U937 and P3H1 cell lines were 29, 29 and 31 microg/mL, respectively. 4. With the exception of HepG2 and Hep3B, the E. sagittatum extract inhibited the proliferation of all cell lines (SK-Hep1, PLC/PRF/5, K562, U937, P3H1 and Raji), with IC50 values of 15, 57, 74, 221, 40 and 80 microg/mL, respectively. 5. Interestingly, the two major compounds of C. chinensis, berberine and coptisine, showed a strong inhibition on the proliferation of both hepatoma and leukaemia cell lines, with IC50 values varying from 1.4 to 15.2 microg/mL and from 0.6 to 14.1 microg/mL, respectively. However, icariin (the major compound of E. sagittatum) showed no inhibition of either the hepatoma or leukaemia cell lines. 6. The results of the present study suggest that the C. chinensis extract and its major constituents berberine and coptisine possess active antihepatoma and antileukaemia activities.
Spontaneous and Context-Aware Media Recommendation in Heterogeneous Spaces (2007)

While mobile users move from one smart space to another, it is highly desirable for them to access the right media contents from the overabundant media information in the right form with their own devices. This paper deals with two important issues in pervasive media access: one is the spontaneous media access in heterogeneous environments, the other is the context-aware media recommendation in different spaces. A general platform for spontaneous media access and context-aware media recommendation has been proposed and implemented. The proposed hybrid recommendation algorithm shows quite good performance in heterogeneous environments.
Interest rates in open economies : real interest rate parity, exchange rates, and country risk in industrial and developing countries (1994)

The paper tests for the relative importance of international capital market integration in determining interest rates in a broad sample of both industrial and developing countries. The recent turbulence in industrial country financial markets has underscored these concerns. One view holds that it is possible for countries to conduct an independent domestic interest rate policy. The other suggests that there is very little room for managing interest rates in open economies without destabilizing effects on exchange rates - given the massive volumes of capital market transactions that force interest rate parity across countries. Interest rate formation in developing countries has attracted much less attention. But it is an increasingly important issue as a growing number of them undertake financial liberalization. The central question for policy-makers is again the degree to which domestic interest rates are influenced by world interest rates. A separate concern is high domestic interest rates, relative to world interest rates, in some developing countries. A model of real interest rate parity is proposed as the main test for capital market integration - that is, that nominal interest rate differences across countries are largely explained by inflation differentials (rather than uncovered or covered nominal interest parity). The evidence suggests strongly that although domestic monetary policies play a significant role, real interest parity is a dominant factor, in both industrial and developing countries. However, expectations of exchange rate changes also significantly influence interest rates. A third key factor is the apparent presence of significantcountry risk, unexplained by macroeconomic imbalances, for some developing countries (for example, Chile, Indonesia, Mexico, and the Philippines) pushing real domestic interest rates higher than what would be otherwise predicted. The concluding section discusses the possible reasons for suchcountry-riskin the case of Indonesia.
Pediatric regional anesthesia: what is the current safety record? (2010)

The use of regional anesthetics, whether as adjuncts, primary anesthetics or postoperative analgesia, is increasingly common in pediatric practice. Data on safety remain limited because of the paucity of very large-scale prospective studies that are necessary to detect low incidence events, although several studies either have been published or have reported preliminary results. This paper will review the data on complications and risk in pediatric regional anesthesia. Information currently available suggests that regional blockade, when performed properly, carries a very low risk of morbidity and mortality in appropriately selected infants and children.
Semantic Models for Scalable Search in the Internet of Things (2013)

The Internet of Things is anticipated to connect billions of embedded devices equipped with sensors to perceive their surroundings. Thereby, the state of the real world will be available online and in real-time and can be combined with other data and services in the Internet to realize novel applications such as Smart Cities, Smart Grids, or Smart Healthcare. This requires an open representation of sensor data and scalable search over data from diverse sources including sensors. In this paper we show how the Semantic Web technologies RDF (an open semantic data format) and SPARQL (a query language for RDF-encoded data) can be used to address those challenges. In particular, we describe how prediction models can be employed for scalable sensor search, how these prediction models can be encoded as RDF, and how the models can be queried by means of SPARQL.
Graphical description of improved thickness sensitivity methods in optical monitoring of thin films (1986)

Level monitoring was described by Macleod and Pelletier 1 and elaborated on by Zhao 2 and has been shown to have error compensation capabilities of potentially great benefit to optical coatings of certain types. The insight into the principles can tend to be obscured by the mathematics for even those with advanced education. We review the principles of level monitoring using circle diagrams to aid in their visualization and show how to design the level monitoring scheme for various cases including the design of precoated monitoring chips. The film thickness sensitivity of various optical monitoring strategies varies considerably. We discuss ways to choose the more sensitive strategies in particular cases to increase the repeatability of the results. Zero level trigger point monitoring offers great sensitivity of change in reflectance vs change in thickness, and it should therefore give small optical thickness errors when optically monitored. We describe zero level trigger point monitoring and how and when it can be applied.
Mutations in the GCD7 subunit of yeast guanine nucleotide exchange factor eIF-2B overcome the inhibitory effects of phosphorylated eIF-2 on translation initiation. (1994)

Phosphorylation of the alpha subunit of eukaryotic translation initiation factor 2 (eIF-2 alpha) impairs translation initiation by inhibiting the guanine nucleotide exchange factor for eIF-2, known as eIF-2B. In Saccharomyces cerevisiae, phosphorylation of eIF-2 alpha by the protein kinase GCN2 specifically stimulates translation of GCN4 mRNA in addition to reducing general protein synthesis. We isolated mutations in several unlinked genes that suppress the growth-inhibitory effect of eIF-2 alpha phosphorylation catalyzed by mutationally activated forms of GCN2. These suppressor mutations, affecting eIF-2 alpha and the essential subunits of eIF-2B encoded by GCD7 and GCD2, do not reduce the level of eIF-2 alpha phosphorylation in cells expressing the activated GCN2c kinase. Four GCD7 suppressors were shown to reduce the derepression of GCN4 translation in cells containing wild-type GCN2 under starvation conditions or in GCN2c strains. A fifth GCD7 allele, constructed in vitro by combining two of the GCD7 suppressors mutations, completely impaired the derepression of GCN4 translation, a phenotype characteristic of deletions in GCN1, GCN2, or GCN3. This double GCD7 mutation also completely suppressed the lethal effect of expressing the mammalian eIF-2 alpha kinase dsRNA-PK in yeast cells, showing that the translational machinery had been rendered completely insensitive to phosphorylated eIF-2. None of the GCD7 mutations had any detrimental effect on cell growth under nonstarvation conditions, suggesting that recycling of eIF-2 occurs efficiently in the suppressor strains. We propose that GCD7 and GCD2 play important roles in the regulatory interaction between eIF-2 and eIF-2B and that the suppressor mutations we isolated in these genes decrease the susceptibility of eIF-2B to the inhibitory effects of phosphorylated eIF-2 without impairing the essential catalytic function of eIF-2B in translation initiation.
Coping with conflict in cooperative knowledge-based systems (1997)

In this paper, we address a critical issue of cooperative problem solving: the existence of conflict among distributed agents. In particular, we focus our study on cooperative knowledge-based systems. To obtain a better understanding and more balanced judgement of multiagent conflict, we provide a general scheme to study the logical structure of multiagent conflict and rational strategies of coping with it under different situations. Our research finding is that there is no grand unified theory of coping with conflict in performing complex real-world computer supported tasks. Instead, a library of alternative methods should be considered. We discuss four methods: inquiry, arbitration, persuasion, and accommodation. These methods can be combined in an order appropriate to the application domain such that if one method fails, the system will try the next. We point out merits and shortcomings of these methods and illustrate them using several high-level protocols and application examples from a prototype system, the Building Design Network.
Methodology and design principles for a generic simulation platform for distributed robotic system experimentation and development (2002)

The high cost of acquiring and operating a collection of advanced autonomous mobile robots for distributed robotic system (DRS) experiments stimulates the interest of developing a generic, real-time, virtual reality based simulation platform. The specification and design principles for such a system is presented. New concepts introduced in the paper include levels of users for the simulation platform, abstract sensors/actuators; the bandwidth of sensing/actuating devices, the bandwidth of a robot and that for the simulation platform; integrating hard systems with computer simulation; and simulated concurrency. A multiprocessor based DRS simulation platform, currently being developed at the Robotics Laboratory, UC Riverside, is used as an example.
[Nicotinamide inhibition of 2-14C acetate incorporation into free fatty acids and lipids of rat tissues]. (1978)

The synthesis of fatty acids and lipids in the rat tissues is inhibited to a considerable extent during fasting and is activated when feeding highly carobhydrate ration to rats after fasting. Nicotinamide (50 mg/100 g of weight) causes a decrease in intensity of 14C incorporation into free fatty acids and lipids of blood, liver, epididimal and perienal fatty tissues. The degree of nicotinamide inhibition of fatty acids and lipids sythesis is in direct dependence on lipogenesis intensity.
Tandem inverse-electron-demand hetero-/retro-Diels–Alder reactions for aromatic nitrogen heterocycle synthesis (2012)

The merged inverse-electron-demand hetero-Diels-Alder (ihDA)/retro-Diels-Alder (rDA) reaction sequence can be used to rapidly synthesise highly functionalised nitrogen heteroaromatics. The reaction offers many advantages: high atom economy, high levels of regioselectivity, it rarely requires a catalyst and, in some cases, can be performed in the absence of solvent. In this tutorial review we discuss the range of commonly used dienophiles and aza-dienes for this process whilst highlighting the reactivity trends, and illustrating their applications.