gebhart/patrepeval huggingface dataset:
A Method for Measuring Deformation Rates in Hydrogel Structures: Multi-Plane Imaging and Measurement Limitations (2000)

Abstract A technique for determining the three dimensional motions of hydrogel structures in microchannels is introduced. In developing this technique, we have adapted microscopic particle image velocimetry (μPIV), a method for measuring velocity fields in microfluidic devices. The motions of 1 μm fluorescent seed particles that are incorporated into a hydrogel microstructure (200 μm tall × 400 μm diameter) are tracked over several expansion cycles using microscopy. Combining measurements taken in different planes produces a three-dimensional representation of the motions present during volume changes can be reconstructed. By providing cross sections of the local deformation rates in hydrogel microstructures, this technique allows for the optimization of device designs as well as providing a better understanding of the processes by which hydrogels change volume under mechanical constraints.
<i>Brucella</i> sp. vertebral osteomyelitis with intercurrent fatal <i>Staphylococcus aureus</i> toxigenic enteritis in a bottlenose dolphin (<i>Tursiops truncatus</i>) (2011)

A previously beach-stranded, juvenile, male, bottlenose dolphin ( Tursiops truncatus) was diagnosed with vertebral osteomyelitis of unknown etiology. Antemortem serological testing suggested past or current Brucella sp. infection; however, this could not be confirmed prior to death despite multiple isolation attempts from aspirates, blood, and biopsies. Systemic antibiotics were administered for over a year to control the suspected infection; however, the animal succumbed peracutely to infection by a highly pathogenic, enterotoxin-secreting Staphylococcus sp. Gross necropsy findings included a fistulous tract leading to locally extensive osteomyelitis of a coccygeal vertebra with sequestra and osteophytes from which a Brucella species was isolated. Histopathological examination of intestine revealed pseudomembranous enteritis with a uniform population of intraluminal Gram-positive cocci. Staphylococcus aureus was isolated in pure culture from the intestine and tested positive for the staphylococcal enterotoxin A gene by polymerase chain reaction analysis. Serum taken shortly before death had endotoxin and elevated antibody titers to staphylococcal enterotoxin A when compared to samples collected during a period of apparent good health 18 months earlier. The isolation of a pyrogenic toxin superantigen-producing staphylococcal isolate, clinical signs, and diagnostic findings in this animal resembled some of those noted in human toxic shock syndrome. The present case highlights the clinical challenges of treating chronic illnesses, complications of long-term antibiotic use, and promotion of pathogenic strains in cases of prolonged rehabilitation of marine mammals.
Tissue-specific changes in size and shape of the ligaments and tendons of the porcine knee during post-natal growth (2019)

Prior studies have analyzed growth of musculoskeletal tissues between species or across body segments; however, little research has assessed the differences in similar tissues within a single joint. Here we studied changes in the length and cross-sectional area of four ligaments and tendons, (anterior cruciate ligament, patellar tendon, medial collateral ligament, lateral collateral ligament) in the tibiofemoral joint of female Yorkshire pigs through high-field magnetic resonance imaging throughout growth. Tissue lengths increased by 4- to 5-fold from birth to late adolescence across the tissues while tissue cross-sectional area increased by 10-20-fold. The anterior cruciate ligament and lateral collateral ligament showed allometric growth favoring change in length over change in cross-sectional area while the patellar tendon and medial collateral ligament grow in an isometric manner. Additionally, changes in the length and cross-sectional area of the anterior cruciate ligament did not increase as much as in the other ligaments and tendon of interest. Overall, these findings suggest that musculoskeletal soft tissue morphometry can vary within tissues of similar structure and within a single joint during post-natal growth.
Middleware-based database replication (2008)

The need for high availability and performance in data management systems has been fueling a long running interest in database replication from both academia and industry. However, academic groups often attack replication problems in isolation, overlooking the need for completeness in their solutions, while commercial teams take a holistic approach that often misses opportunities for fundamental innovation. This has created over time a gap between academic research and industrial practice.
The role of HIV in serious diseases other than AIDS (2008)

Udgivelsesdato: 2008-Nov-30
Microflora of partially processed lettuce (1990)

Bacteria, yeasts, and molds isolated from partially processed iceberg lettuce were taxonomically classified. The majority of bacterial isolates were gram-negative rods. Pseudomonas, Erwinia, and Serratia species were commonly found. Yeasts most frequently isolated from lettuce included members of the genera Candida, Cryptococcus, Pichia, Torulaspora, and Trichosporon. Comparatively few molds were isolated; members of the genera Rhizopus, Cladosporium, Phoma, Aspergillus, and Penicillium were identified.
ChemInform Abstract: KINETIC STUDY OF THE HOMOLYTIC BROMINOLYSIS OF 1,2‐DIARYLCYCLOPROPANES (1981)

Abstract 1,2‐Diaryl‐cyclopropane (I) werden photolytisch durch Brom zu den 1,3‐Diaryl‐1,3‐dibrompropanen (II) gespalten.
Optical coating on nano-optical antennas to enhance directional radiation (2015)

A traditional high-reflection optical coating was applied to enhance the directional radiation of nanoantennas. A highly reflective multilayer upon the top lateral side of a horizontally lying silver nanorod enhances the forward scattering when an optical wave is incident on the bare bottom side of the nanorod. Enhanced forward scattering can thus be observed from a glancing deposited silver nanorod array (NRA). An effective method for coupling the energy of incident light into a NRA involves arranging the NRA in a prism coupling. The highly efficient light coupling effect over a broadband and a wide range of angles results in extra-strong forward light scattering.
Loss of α‐tocopherol upon exposure to nitric oxide or the sydnonimine SIN‐1 (1993)

SIN‐1 which spontaneously decomposes to yield nitric oxide (NO . and Superoxide anion (O 2 .− radicals caused a loss of microsomal α‐tocopherol paralleled by the formation of α‐tocopheryl quinone. The loss was partially prevented by Superoxide dismutase but not by catalase. The SIN‐1‐induced loss of α‐tocopherol also occurred when tocopherol was dissolved in ethanol/potassium phosphate buffer (20/80, v/v). Likewise, addition of authentic NO . to α‐tocopherol dissolved in ethanol resulted in loss of the vitamin and quinone formation. These results suggest that NO . or its products such as peroxynitrite or nitrogen dioxide react with α‐tocopherol, the quinone derivative being a major oxidation product. Depletion of vitamin E by NO . may contribute to tissue injury, e.g. in neuronal tissues.
Recurrent genomic alterations in benign and malignant pheochromocytomas and paragangliomas revealed by whole-genome array comparative genomic hybridization analysis (2010)

Pheochromocytomas and abdominal paragangliomas are adrenal and extra-adrenal catecholamine-producing tumours. They arise due to heritable cancer syndromes, or more frequently occur sporadically due to an unknown genetic cause. The majority of cases are benign, but malignant tumours are observed. Previous comparative genomic hybridization (CGH) and loss of heterozygosity studies have shown frequent deletions of chromosome arms 1p, 3q and 22q in pheochromocytomas. We applied high-resolution whole-genome array CGH on 53 benign and malignant pheochromocytomas and paragangliomas to narrow down candidate regions as well as to identify chromosomal alterations more specific to malignant tumours. Minimal overlapping regions (MORs) were identified on 16 chromosomes, with the most frequent MORs of deletion (> or = 32%) occurring on chromosome arms 1p, 3q, 11p/q, 17p and 22q, while the chromosome arms 1q, 7p, 12q and 19p harboured the most common MORs of gain (> or = 14%). The most frequent MORs (61-75%) in the pheochromocytomas were identified at 1p, and the four regions of common losses encompassed 1p36, 1p32-31, 1p22-21 and 1p13. Tumours that did not show 1p loss generally demonstrated aberrations on chromosome 11. Gain of chromosomal material was significantly more frequent among the malignant cases. Moreover, gain at 19q, trisomy 12 and loss at 11q were positively associated with malignant pheochromocytomas, while 1q gain was commonly observed in the malignant paragangliomas. Our study revealed novel and narrow recurrent chromosomal regions of loss and gain at several autosomes, a prerequisite for identifying candidate tumour suppressor genes and oncogenes involved in the development of adrenal and extra-adrenal catecholamine-producing tumours.
Articulating Factors Defining RMS Delay Spread in LV PLC Networks (2010)

Communication over the power line network (PLN) referred as power line communication (PLC) has a long history of narrowband applications. With the recent developments in the field of digital communications, current interest is to exploit this medium for wideband communications for several applications such as Internet access, home networking, and in-vehicle data communication. In line with this recently emerging interest which envisions the conversion of a power transmission network into a communication network, understanding the root-mean-squared (RMS) delay spread is essential for multipath PLC channels for the establishment of reliable communication systems. In this paper, factors that play a role on the RMS delay spread value of low voltage (LV) PLC channels are articulated. Among these factors, dependency of the RMS delay spread on attenuation, loading, and physical characteristics of the communication channel in the PLNs is investigated.
A macromodel compaction scheme for the fast simulation of large linear mesh circuits (2002)

Analysis of large linear mesh circuits is critical in modern IC extraction and verification tools due to the complex 3-D effects associated with parasitic coupling through interconnects and the chip substrate. The limited availability of computer resources, however, is a major obstacle in the fast and accurate analysis of such circuits. This paper introduces a technique that divides the mesh into a number of partitions, develops macromodels of each partition using a compaction technique and then combines them in a nested fashion to determine a macromodel for the original mesh circuit, which can then be used in simulation. This method makes much better use of CPU time and memory and allows for the fast analysis of extremely large meshes.
MALDI imaging: a new technology to discover and validate new biomarkers (2007)

International audience
Electron impact-ionization effects in UHV/CVD SiGe HBT's in the temperature range of 300 to 83 K (1998)

The electron impact-ionization rates (M-1) in SiGe HBT's are investigated using a new technique in the temperature range of 300 to 83K. In the new technique, the initial current for avalanche multiplication is explicitly controlled in the presence of Early effect and self-heating, and the low V CB limitation set by the open emitter current I CBC is removed. With cooling, M-1 increases first, and then saturates. when T < 117K. A 2.3V critical reverse CB voltage at which base current reversal occurs is observed at 83K, which is sufficiently high for today's bipolar and BiCMOS logic applications. Comparison with the silicon control devices suggests that the M-1 is not increased by the incorporation of SiGe, despite its smaller bandgap, indicating that SiGe HBT's are suitable for RF power applications.
Conformations of macromolecules (2006)

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The Influence of the Microstructure of Thermal Barrier Coating Systems on Sintering and Other Properties (2002)

Abstract This paper investigates the influence of microstructure on the sintering behavior of thermal barrier coatings. A significant difference is observed between coatings with typical microcracks and those with segmentation cracks. Segmented coatings showed a lower sintering rate and little change in pore size distribution after heat treatment. Conventional coatings, on the other hand, showed an increase in pore diameter and in more porous areas, sintering was more pronounced. All coatings had an elastic modulus in the range of 15-20 GPa, which more than doubled after a 10-h heat treatment at 1200 °C. Paper includes a German-language abstract.
Augmentation of urea‐synthetic capacity by inhibition of nitric oxide synthesis in butyrate‐induced differentiated human hepatocytes (2000)

We have recently developed an in vitro differentiation model of immortalized non-transformed human hepatocytes using butyrate, and observed the induction of inducible NO synthase (iNOS). In this study, we analyzed the effect of NO on the urea-synthetic capacity of these cells. The inhibition of iNOS during butyrate treatment significantly increased the urea-synthetic capacity as compared to that of butyrate treatment alone, possibly through the further induction of ornithine transcarbamylase expression. Therefore, the inhibition of NO production might be useful for obtaining more differentiated hepatocytes in the process of in vitro induction of hepatocyte-specific differentiation.
A Double-Quantum Solid-State NMR Technique for Determining Torsion Angles in Polymers (1996)

This paper introduces a double-quantum solid-state NMR experiment for determining torsion angles in unoriented polymers which contain segments with pairs of 13C-labeled sites separated by only one or two bonds. By double-quantum excitation and evolution, two-dimensional spectra are obtained in which the first dimension displays the sum of the anisotropic chemical shifts. As a consequence, the two-dimensional spectral patterns depend on the relative orientation of the coupled sites and thus on the torsion angle. The double-quantum approach achieves homonuclear dipolar decoupling in the first dimension without multiple-pulse sequences and removes the natural-abundance background signal. The experiment is demonstrated on polyethylene isotopically labeled with dilute (∼4%) 13C−13C spin pairs and confirms the all-trans structure in the crystalline regions. In polypeptides, it will be applicable to the determination of the backbone torsion angle ψ in a doubly 13C-labeled amino acid residue, with a sensitivity to analyze one residue in a repeat unit comprising up to 20 residues.
Manufacture of a Prototype Advanced Permanent Magnet Motor Pod (2003)

Podded propulsion is prevalent in the marine industry. Podded propulsion systems provide many advantages to the ship owner, including increased propulsion efficiency and reduced construction cost. To evaluate the potential of a new pod configuration, a prototype machine was constructed and tested. This prototype machine was mainly constructed of composite parts. The propeller, housings, structural blading, motor canning, and fairings were constructed of composite materials. Composite materials were chosen as a cost saving, schedule reduction, performance enhancement, and as a technology demonstration. This paper will review the unit construction, and test results, focusing on the lessons learned for the composite part manufacture.
A convex set based optimization algorithm for structural reliability analysis (2001)

In certain applications of structural reliability, it is required to find points on the limit-state surface with minimal distance to the origin of the standard normal space. This problem can be formulated as a constrained optimization problem and several algorithms can be used in the solution. In this paper, a convex set approach is used along with a penalty method for the solution of this constrained minimization problem. Several problems are solved to demonstrate the generality, robustness, and efficiency of the new method.
PDMS as a sacrificial substrate for SU-8-based biomedical and microfluidic applications (2008)

We describe a new fabrication process utilizing polydimethylesiloxane (PDMS) as a sacrificial substrate layer for fabricating free-standing SU-8-based biomedical and microfluidic devices. The PDMS-on-glass substrate permits SU-8 photo patterning and layer-to-layer bonding. We have developed a novel PDMS-based process which allows the SU-8 structures to be easily peeled off from the substrate after complete fabrication. As an example, a fully enclosed microfluidic chip has been successfully fabricated utilizing the presented new process. The enclosed microfluidic chip uses adhesive bonding technology and the SU-8 layers from 10 µm to 450 µm thick for fully enclosed microchannels. SU-8 layers as large as the glass substrate are successfully fabricated and peeled off from the PDMS layer as single continuous sheets. The fabrication results are supported by optical microscopy and profilometry. The peel-off force for the 120 µm thick SU-8-based chips is measured using a voice coil actuator (VCA). As an additional benefit the release step leaves the input and the output of the microchannels accessible to the outside world facilitating interconnecting to the external devices.
Noise Filtering, Channel Modeling and Energy Utilization in Wireless Body Area Networks (2012)

Constant monitoring of patients without disturbing their daily activities can be achieved through mobile networks. Sensor nodes distributed in a home environment to provide home assistance gives concept of Wireless Wearable Body Area Networks. Gathering useful information and its transmission to the required destination may face several problems. In this paper we figure out different issues and discuss their possible solutions in order to obtain an optimized infrastructure for the care of elderly people. Different channel models along with their characteristics, noise filtering in different equalization techniques, energy consumption and effect of different impairments have been discussed in our paper. The novelty of this work is that we highlighted multiple issues along with their possible solutions that a BAN infrastructure is still facing.
Synthesis and characterization of biocompatible and biodegradable poly(ϵ‐caprolactone‐b‐γ‐benzylglutamate) diblock copolymers (1993)

peer reviewed
Zhx2 protects the liver from high‐fat induced liver damage (2010)

Obesity is a significant and growing health concern in the US due to its associated risks, including atherosclerosis and nonalcoholic fatty liver disease. A recent genetic study, identified a QTL on mouse chromosome 15, called hyplip2, associated with hyperlipidemia and increased atherosclerotic lesions (ATVB, 24:1928). We have found that the zinc‐finger and homeoboxes 2 (Zhx2) gene (PNAS, 102:396) is responsible for the hyplip2 phenotype. The objective of this study is to understand the role of Zhx2 in liver function during a high fat diet. BALB/c (wild‐type Zhx2) and BALB/cJ (mutant Zhx2) female mice were fed a normal or high fat diet. AFP mRNA and serum ALT levels were elevated in BALB/cJ on the high fat diet compared to all other groups. Hepatic TNF mRNA levels increased in response to the high fat diet but were not significantly different between the two strains. CYP8B1 (involved in bile acid synthesis) mRNA levels were higher in BALB/cJ than BALB/c on the high fat diet. This data suggests that Zhx2 may protect the liver from high fat‐induced damage and involved in regulating lipid metabolic enzymes.
Speeding up database applications with Pyxis (2013)

We propose to demonstrate Pyxis, a system that optimizes database applications by pushing computation to the database server. Our system applies program analysis techniques to the application source code to determine pieces of application logic that should be moved to the database server to improve performance. This frees the developer from the need to understand the intricacies of database operations or learn a new programming language for stored procedures. In addition, by dynamically monitoring resource utilization on the database server, Pyxis can migrate computation between application and database in response to workload changes. Our previous experiments have shown that Pyxis can decrease latency up to 3x for transactional applications, and improve throughput up to 1.7x when compared to a standard implementation using embedded SQL statements in application logic. We will demonstrate these capabilities via a visualization of real-time performance as well as an interactive code partitioning tool we have developed.
A Framework for Ethernet Tree (E-Tree) Service over a Multiprotocol Label Switching (MPLS) Network (2014)

This document describes an Ethernet-Tree (E-Tree) solution framework for supporting the Metro Ethernet Forum (MEF) E-Tree service over a Multiprotocol Label Switching (MPLS) network.The objective is to provide a simple and effective approach to emulate E-Tree services in addition to Ethernet LAN (E-LAN) services on an existing MPLS network.
Synthesis and Electrochemical Properties of Redox-Active [2]Rotaxanes Based on the Inclusion Complexation of 1,4-Phenylenediamine and Benzidine by Cyclobis(paraquat-p-phenylene) (1995)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSynthesis and Electrochemical Properties of Redox-Active [2]Rotaxanes Based on the Inclusion Complexation of 1,4-Phenylenediamine and Benzidine by Cyclobis(paraquat-p-phenylene)Emilio Cordova, Richard A. Bissell, and Angel E. KaiferCite this: J. Org. Chem. 1995, 60, 4, 1033–1038Publication Date (Print):February 1, 1995Publication History Published online1 May 2002Published inissue 1 February 1995https://pubs.acs.org/doi/10.1021/jo00109a040https://doi.org/10.1021/jo00109a040research-articleACS PublicationsRequest reuse permissionsArticle Views411Altmetric-Citations70LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Poly(phenylene ether ketones) prepared by electrophilic polycondensation methods (1991)

Abstract Poly(phenylene ether ketones) were prepared by polyacylation reactions in hydrogen fluoride‐boron trifluoride and by aluminum trichloride promoted Friedel‐Crafts reactions modified by Lewis bases. Structural and engineering properties of these polymers are presented.