gebhart/patrepeval huggingface dataset:
3D orthorhombic elastic full-waveform inversion in the reflection domain from hydrophone data (2016)

We formulate the theory of 3D orthorhombic full-waveform inversion using adjoint state techniques for recovery of shear and p-wave elastic stiffness coefficients from acquired pressure data. In formulating the adjoint of forward Born scattering, we use a novel transformation of wavefields that allows us to use the same high performance elastic propagation kernel for the adjoint that we use for forward elastic modeling. We further derive inversion equations suitable for recovery of p-wave and shear velocities in fixed inhomogeneous density media with fixed inhomogeneous anisotropic coefficients, through the use of a chain rule formulation. We demonstrate that for a simple model with a strong Class 2 AVO signature involving phase reversal, a sequence of short-offset p-wave elastic stiffness recovery (equivalently velocity or impedance) folllowed by long offset shear elastic stiffness recovery produces a significant uplift in data fitting when compared to simple acoustic inversion for p-wave velocity. We also demonstrate effective recovery in 2D using similar techniques, for a more complex model with thin sands exhibiting strong AVO behavior. Presentation Date: Tuesday, October 18, 2016 Start Time: 8:00:00 AM Location: 146 Presentation Type: ORAL
Glucose and lipid metabolism in young lean normotensive males with the G protein beta3 825T-allele. (2003)

The 825T-allele of the C825T polymorphism in GNB3, the gene for the G protein beta3 subunit, has been reported to be associated with essential hypertension and obesity. Expression of Gbeta3s, the gene product of GNB3 associated with the GNB3 825T-allele, causes increased signal transduction which may contribute to pathogenetic mechanisms ultimately resulting in hypertension and obesity. Given the known involvement of heterotrimeric G proteins in insulin secretion and insulin action on the cellular level, we analysed insulin sensitivity in each 15 young lean normotensive males with TC- and CC-genotypes, respectively. Blood glucose and serum insulin samples were taken during a standard oral glucose tolerance test. Insulin-stimulated glucose disposal was analysed by euglycemic-hyperinsulinemic clamp. Both groups did not differ with regard to the time-courses for glucose or insulin concentrations in the oral glucose tolerance test. Furthermore, insulin-stimulated glucose disposal was virtually independent of genotype. The TC-genotype is not associated with a primary defect in insulin secretion or sensitivity suggesting that obesity and hypertension in carriers of 825T do not likely result from primary alterations in glucose and insulin homeostasis. However, GNB3 825T-associated obesity may predispose to insulin resistance, an issue which remains to be investigated. Furthermore, fasting cholesterol was significantly higher in TC compared to CC genotype (4.71 versus 3.96 mmol/l; p = 0.007) suggesting that enhanced G protein signalling might be associated with alterations of cholesterol metabolism.
Workflow Strategies (1997)

From the Publisher:
While may sound abstract, it's at the heart of intranet and corporate enterprise network development. Fast Ethernet, FireWire, Windows NT, IntranetWare -- all these things can only be part of streamlining and enhancing how organizations of people work together. Indeed, they count for nothing if an efficient workflow management system isn't in place.
In Workflow Strategies, Network World contributing editor and recognized authority on strategic telecommunications and information systems James Kobielus offers an understandable, practical examination of the critical issues confronting organizations as they reengineer their technological infrastructure to take advantage of cutting-edge computing, networking, and telecommunications advances. More importantly, Kobielus provides real-world guidance on implementing workflow management strategies so that the productivity and efficiency of employees increases right along with customer and client satisfaction -- which of course is what it's all about.

In Kobielus' own words,

This book illustrates the technical backbone behind the often fuzzy concept of business-process reengineering. It shows the average business reader how to start from a small-scale workflow pilot and scale up as appropriate to a complex, enterprise-wide information routing and tracking system. The focus is always on the bottom line: illustrating how workflow applications can help you increase the speed, flexibility, and efficiency of your business processes.

Aimed not only at information systems and telecommunications professionals but also atbusiness professionals responsible for business-process reengineering, Workflow Strategies is the most complete workflow guide available today. If you're ready to get beyond the buzzwords and hype of intranets, groupware, and the like, be sure to check out Workflow Strategies.
An Infovis approach to compare ATC comets : A theoretical basis for comparing visual entities (2008)

International audience
Optical Double Negative Metamaterial at 813 nm (2007)

A negative index metamaterial demonstrating n = -1.0 + 0.8i with both negative effective permittivity and permeability at 813 nm of linearly polarized light is fabricated. It also exhibits a negative refractive index (n = -0.7 + 1.3i) at 772 nm for orthogonal polarization.
Time course analysis of gene expression identifies multiple genes with differential expression in patients with in-stent restenosis (2011)

In a study of patients undergoing bare metallic stent implantation, we have identified and replicated differential gene expression in peripheral blood mononuclear cells, studied across a time series of blood samples. The genes identified suggest alterations in cellular growth and metabolism pathways, and these results provide the basis for further specific functional hypothesis generation and testing of the mechanisms of ISR.
Influence of the <i>n</i>-Hexoxy Group on the Properties of Fluoroalkoxyphosphazene Polymers (2004)

ADVERTISEMENT RETURN TO ISSUEPREVNoteNEXTInfluence of the n-Hexoxy Group on the Properties of Fluoroalkoxyphosphazene PolymersAndrew E. Maher and Harry R. AllcockView Author Information Department of Chemistry, 104 Chemistry Building, The Pennsylvania State University, University Park, Pennsylvania 16802 Cite this: Macromolecules 2005, 38, 2, 641–642Publication Date (Web):December 30, 2004Publication History Received10 March 2004Revised5 October 2004Published online30 December 2004Published inissue 1 January 2005https://pubs.acs.org/doi/10.1021/ma0495184https://doi.org/10.1021/ma0495184brief-reportACS PublicationsCopyright © 2005 American Chemical SocietyRequest reuse permissionsArticle Views239Altmetric-Citations6LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Elastomers,Materials,Mesostructures,Polymers,Substituents Get e-Alerts
A miniprep procedure for isolating genomic DNA from Magnoporthe grisea (1990)

We have developed a simple miniprep procedure for the isolation of genomic DNA from the ascomycete Magnaporthe grisea. This pathogen of many grasses, including rice, has a moderate growth rate and produces intermediate to low numbers of conidia when grown in culture. Thus, in our previous DNA preparation procedure we inoculated swirling liquid cultures with mycelium that had been fragmented in a blender rather than with conidia. The mycelium obtained from these cultures was ground in liquid nitrogen for DNA extraction. Though the quantity and quality of DNA obtained by this method is satisfactory, the technique is too laborious for analysis of many strains. We developed the procedure described below to eliminate the need to fragment mycelium in a blender to inoculate cultures and to eliminate the need to grind mycelium in liquid nitrogen for DNA extraction. The new procedure, which relies on the enzymatic removal of cell walls and the lysis of protoplasts, should be readily adaptable to other filamentous fungi with growth characteristics similar to those of M. grisea.
Abstract P2-04-26: Identifying patient-specific neoepitopes for cell-based and vaccine immunotherapy across breast cancer classifications reveals rarely shared recurrent neoepitopes (2017)

Abstract Introduction: Targeted therapies for breast cancers such as trastuzumab and everolimus have durable clinical benefits for patients that express the relevant biomarkers (HER2 and mTOR respectively). Triple negative breast cancer patients lack these biomarkers and are left with few options. Recent advances in immunotherapy agents against PD-1/CTLA4 for patients with melanoma have yielded amazing clinical benefits for a subset of patients and may have similar results in breast cancer patients, but again the vast majority of patients still undergo disease progression. We analyzed whole genome sequencing (WGS) and RNA sequencing data from The Cancer Genome Atlas (TCGA) to identify neoepitopes among breast cancer patients that could be used to develop next-generation, patient-specific cancer immunotherapies. Neoepitopes are tumor specific markers that arise from mutations acquired from cancer and may represent a path to targeted therapies even in triple negative breast cancers. Results: We analyzed 99 breast cancer patients from TCGA, containing a mixture of PR+/HER2+/ER+ and TNBC classifications. These breast cancer patient samples were selected by the availability of whole genome sequencing (WGS) data, RNA-sequencing data as well as clinical outcome data. We identified an average of 680 potential neoepitopes per patient based solely on WGS data. To further refine and select high quality neoepitopes we restricted these neoepitopes based on gene expression yielding an average of 304 expressed neoepitopes per patient. We predicted each patient's HLA typing using only omics data, which we then used to predict HLA-expressed neoepitope binding analysis resulting in an average of 11 high-quality tumor specific neoepitopes per patient. We identified few recurrent neoepitopes that were bound and expressed, indicating the need for a personalized medicine approach. Conclusions: Within the TCGA dataset, the majority of neoepitopes among patients with breast cancer were unique to each patient. Rarely within subsets of breast cancers such as HER2+, we identify neoepitopes that are shared between patients. For breast cancer patients who do not respond to targeted therapies, high-throughput identification of neoepitopes could serve as the basis for the development of next-generation, patient-specific immunotherapies. Citation Format: Nguyen A, Sanborn JZ, Vaske CJ, Rabizadeh S, Niazi K, Soon-Shiong P, Benz SC. Identifying patient-specific neoepitopes for cell-based and vaccine immunotherapy across breast cancer classifications reveals rarely shared recurrent neoepitopes [abstract]. In: Proceedings of the 2016 San Antonio Breast Cancer Symposium; 2016 Dec 6-10; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2017;77(4 Suppl):Abstract nr P2-04-26.
ChemInform Abstract: SYNTH. VON POLYGODIAL (1971)

Abstract Im Zusammenhang mit der Synthese des aus Polygonum hydropiper isolierten Polygodials (VIII) werden aus Monocyclofamesinsäure (I) die angegebenen Reaktionsprodukte hergestellt.
Linear Non Linear Digital control for DC/DC Converters with fast transient response PARTE II (2009)

This article presents a digital control that improves the stability of the system, solves the problem of the limit cycle, shortens the recovery time and limits the overcoming of the rectified output voltage. The digital linear-nonlinear control function for DC / DC converters is described. The simulation model in the mixed environment of matlab-simulink / active -hdl is described. Preliminary results of the preliminary hardware test on a step-down-phase converter are presented and simulation and experimental results are also presented.
Efficacy of supraspinatus tendon repair using mesenchymal stem cells along with a collagen I scaffold (2015)

The implantation of MSCs along with a collagen I scaffold into surgically created tendon defects is safe and effective. MSCs improved the tendon's maximum load over time, indicating that MSCs could help facilitate the dynamic process of tendon repair.
Double Depth First Search Based Parametric Analysis for Parametric Time-Interval Automata (2005)

In this paper, we propose a parametric model checking algorithm for a subclass of Timed Automata called Parametric Time-Interval Automata(PTIA). In a PTIA, we can specify upper-and lower-bounds of the execution time (time-interval) of each transition using parameter variables. The proposed algorithm takes two inputs, a model described in a PTIA and a property described in a PTIA accepting all invalid infinite/finite runs (called a never claim), or valid finite runs of the model. In the proposed algorithm, firstly we determinize and complement the given property PTIA if it accepts valid finite runs. Secondly, we accelerate the given model, that is, we regard all the actions that are not appeared in the given property PTIA as invisible actions and eliminate them from the model while preserving the set of visible traces and their timings. Thirdly, we construct a parallel composition of the model and the property PTIAs which is accepting all invalid runs that are accepted by the model. Finally, we perform the extension of Double Depth First Search(DDFS), which is used in the automata-theoretic approach to Linear-time Temporal Logic(LTL) model checking, to derive the weakest parameter condition in order that the given model never executes the invalid runs specified by the given property.
Identity, Security and XML Web Services (2003)

The use of security credentials and concepts of single-sign-on and “identity” play a big part in Web Services as developers start writing enterprise-grade line-of-business applications. An overview is provided of the emerging XML security credential standards such as SAML, along with various “identity” standards such as Passport and Liberty. We examine how “identity aware” Web Service implementations need to be, and the value a Web Services platform can add in reducing complexity in this area, with lessons drawn from experiences using J2EE technology for real-world security scenarios.
Aerospace Sensors (1995)

The prelims comprise: Introduction Market Structure General Requirements for Aerospace Systems Sensor Types and Technological Trends Market Trends Summary Acknowledgments References
[A case of large cell carcinoma of the lung producing granulocyte colony-stimulating factor]. (1994)

A 48-year-old female was admitted complaining of cough and right chest pain. A chest X-ray showed a tumorous mass in the right lower lung field and hilar and mediastinal lymphadenopathy. The patient underwent transbronchial lung biopsy, and was diagnosed as having a malignant tumor. Because a metastatic lesion was detected in the left lung filed, we opted for chemotherapy. The white blood cell count rose to 103,700/mm3 and 190,000/mm3 in the fifth and sixth month after hospitalization, respectively. The serum granulocyte colony-stimulating factor (G-CSF) level by enzyme immunoassay exceeded 1000 pg/ml. The histological diagnosis of large cell carcinoma was made from the specimen obtained by percutaneous needle biopsy of the lung. The carcinoma cells in this specimen, showed positive staining with anti-G-CSF monoclonal antibody.
Development of a simple in vitro digestion model suitable for multi‐nutrient food systems (2012)

In vitro digestion models screen kinetics of digestion of nutrients, as alternatives to in vivo testing. Most models digest only one type of macronutrient. We developed a batch in vitro digestion model for ranking digestion of all macronutrients alone, mixed, or as whole food. Ingredients are sequentially agitated with saliva, gastric, and duodenal/bile solutions at 37°C for up to 72 h. Ingredients are characterized by: primary structure (PS), physical form (PF), and controlled architecture (CA). We selected ingredients of known digestibility and predicted their rate (slow/fast) and extent (complete/incomplete) of digestion. Selected rate examples Nutrient: Concept Digestibility PS CHO: High Amylose (Amy) slows digestion Proteins: Native structure Waxy corn starch (CS) > common CS>50%Amy CS Casein≈Whey≈Soy>Pea>Rice PF CHO:Gelatinization increases digestion Proteins: Processing Lipids: Higher melting point (MP) slows digestion Gelatinized CS >Native 50% Amy CS Native Soy>Freeze dried soy Olive oil >high MP solid fats CA Whole food: Processing Bread Whole wheat (WW) flour >Raw WW flour The model is suitable for digestion of mixed macronutrients and appropriately ranks their rate/extent of digestion on basis of PS, PF, and CA. Applications include slowed digestion as a satiety marker, and enhanced digestibility for clinical/animal husbandry use. Comparative studies in pigs are ongoing. Funded by Cargill Inc.
Ku Band High-Q Tunable Surface-Mounted Cavity Resonator Using RF MEMS Varactors (2011)

This paper presents a 14 GHz high-Q (quality factor) tunable resonator using microelectromechanical system (MEMS) varactors. A brass surface mountable cavity has been bonded on a fused silica wafer on which are processed three 1.1 mm long MEMS varactors. Their location has been optimized in order to obtain a wide frequency shift, when the cantilevers are actuated on the substrate. 15% tuning range from 11.9 GHz to 14.2 GHz has been obtained with a continuous shift from 11.9 GHz to 13.6 GHz. Measurements result in an average unloaded quality factor ( <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">Qu</i> ) of 480 over the operating frequency band.
Observation of Kosterlitz‐Thouless Transition and Conductivity Fluctuation in Superconducting Ybco Thin Films (1990)

Kosterlitz-Thouless properties of laser deposited high Tc superconducting thin films of YBa2Cu3O7-x were examined. The exponent of the power law dependence of V on I showed a “universal jump” at Tc. ID like conductivity fluctuation was also found at temperatures slightly above the mean-field transition temperature Tco, which may be the result of imperfections of the sample.
Fusion Moves for Markov Random Field Optimization (2009)

The efficient application of graph cuts to Markov Random Fields (MRFs) with multiple discrete or continuous labels remains an open question. In this paper, we demonstrate one possible way of achieving this by using graph cuts to combine pairs of suboptimal labelings or solutions. We call this combination process the fusion move. By employing recently developed graph-cut-based algorithms (so-called QPBO-graph cut), the fusion move can efficiently combine two proposal labelings in a theoretically sound way, which is in practice often globally optimal. We demonstrate that fusion moves generalize many previous graph-cut approaches, which allows them to be used as building blocks within a broader variety of optimization schemes than were considered before. In particular, we propose new optimization schemes for computer vision MRFs with applications to image restoration, stereo, and optical flow, among others. Within these schemes the fusion moves are used 1) for the parallelization of MRF optimization into several threads, 2) for fast MRF optimization by combining cheap-to-compute solutions, and 3) for the optimization of highly nonconvex continuous-labeled MRFs with 2D labels. Our final example is a nonvision MRF concerned with cartographic label placement, where fusion moves can be used to improve the performance of a standard inference method (loopy belief propagation).
LOCKSMITH (2006)

One common technique for preventing data races in multi-threaded programs is to ensure that all accesses to shared locations are consistently protected by a lock. We present a tool called LOCKSMITH for detecting data races in C programs by looking for violations of this pattern. We call the relationship between locks and the locations they protect consistent correlation, and the core of our technique is a novel constraint-based analysis that infers consistent correlation context-sensitively, using the results to check that locations are properly guarded by locks. We present the core of our algorithm for a simple formal language λ> which we have proven sound, and discuss how we scale it up to an algorithm that aims to be sound for all of C. We develop several techniques to improve the precision and performance of the analysis, including a sharing analysis for inferring thread locality; existential quantification for modeling locks in data structures; and heuristics for modeling unsafe features of C such as type casts. When applied to several benchmarks, including multi-threaded servers and Linux device drivers, LOCKSMITH found several races while producing a modest number of false alarm.
Modified Crystallization in PET/PPS Bicomponent Fibers Revealed by Small-Angle and Wide-Angle X-ray Scattering (2012)

We present a small-angle X-ray scattering (SAXS) and wide-angle X-ray scattering (WAXS) characterization of the semicrystalline structure of homo- and heterobicomponent core–sheath fibers melt-spun from poly(ethylene terephthalate) (PET) and poly(phenylene sulfide) (PPS). The two-dimensional SAXS/WAXS patterns of the various bicomponent fibers are found to reflect the mutual influence of the components on their thermal profiles along the spinline, leading to modified crystallization of the PET component and a larger strain rate in the PPS component. The predominant scattering features in the SAXS patterns are four-point reflections, an intense equatorial streak, and a central anisotropic diffuse scattering. The four-point reflections are attributed to tilted crystalline lamellar stacks of PET. The lamellar stack dimensions and the orientation of their lamellar surfaces are determined. We find that the heterobicomponent arrangement can promote the formation of equally spaced and uniformly sized crystallites in the PET phase and highly oriented crystallites in the PPS phase.
Purchase of a Gas Chromatograph-Mass Spectrometer (1990)

Abstract : This report summarizes the final results of the purchase, acquisition and installation of a Hewlett-Packard Model 5988A Gas Chromatograph-Mass Spectrometer. Gas chromatograph, Mass spectrometer, GC-MS, Nuclear instrumentation, Physical chemistry.
High absorption GaAs/AlGaAs quantum well infrared photodetectors (2002)

NRC publication: Yes
ChemInform Abstract: A Synthesis of Novel Perfluoro Dienes. (1991)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: DYNAMIC NMR STUDY OF 3‐METHYLENE‐1‐OXASPIRO(4,5)DECAN‐2‐ONE AND SINGLE‐CRYSTAL X‐RAY DIFFRACTION ANALYSIS OF CIS‐8‐TERT‐BUTYL‐3‐METHYLENE‐1‐OXASPIRO(4,5)DECAN‐2‐ONE (1979)

Abstract Der nach bekannten Verfahren erhaltene Brommethyl‐acrylsäureester (II) liefert mit den Cyclohexanonen (I) isomere Addukte (III) sowie durch deren Cyclisierung isomere Spirocyclen (IV).