gebhart/patrepeval huggingface dataset:
Stability of bulk Ba sub 2 YCu sub 3 O(7-x) in a variety of environments (1988)

Small bars of ceramic Ba2YCu3O(7-x) were fabricated and subjected to environments similar to those that might be encountered during some NASA missions. These conditions include ambient conditions, high humidity, vacuum, and high fluences of electrons and protrons. The normal state resistivity or critical current density (J sub c) were monitored during these tests to assess the stability of the material. When normal state resistivity is used as a criterion, the ambient stability of these samples was relatively good, exhibiting only a 2 percent degradation over a 3 month period. The humidity stability was shown to be very poor, and to be a steep function of temperature. Samples stored at 50 C for 40 min increased in normal state resistivity by four orders of magnitude. Kinetic analysis indicates that the degradation reaction is second order with water vapor concentration. It is suspected that humidity degradation also accounts for the ambient instability. The samples were stable to vacuum over a period of at least 3 months. Degradation of J sub c in a 1 MeV electron fluence of 9.7 x 10 to the 14th e(-)/sq cm was determined to be no more than about 2 percent. Degradation of J sub c inmore » a 8.7 x 10 to the 14th p(+)/sq cm of 42 MeV protons was found to be grain size dependent. Samples with smaller grain size and initial J sub c of about 240 A/sq cm showed no degradation. while that with larger grain size and an initial J sub c of about 30 A/sq cm degraded to 37 percent of its original value.« less
Radical polymerization of vinyl monomers containing cyclotriphosphazene and thermal behavior of their polymers (1989)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTRadical polymerization of vinyl monomers containing cyclotriphosphazene and thermal behavior of their polymersKenzo Inoue, Masato Nakano, Masataka Takagi, and Teiichi TanigakiCite this: Macromolecules 1989, 22, 4, 1530–1533Publication Date (Print):April 1, 1989Publication History Published online1 May 2002Published inissue 1 April 1989https://pubs.acs.org/doi/10.1021/ma00194a004https://doi.org/10.1021/ma00194a004research-articleACS PublicationsRequest reuse permissionsArticle Views240Altmetric-Citations31LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Velocity Distributions of Food Particle Suspensions in Holding Tube Flow: Experimental and Modeling Studies on Average Particle Velocities (1990)

ABSTRACT Average particle velocities of model food particles were investigated by videotaping particles suspended in sodium carboxymethylcellulose solutions during passage through a transparent holding tube similar in dimension to that of commercial aseptic processing systems. Results indicated the mean normalized velocity of particles was significantly affected by particle Froude number and a dimensionless viscosity. Within the range of this study, particle concentration effects were significant only with respect to standard deviations of distributions. Generalized Reynolds number poorly correlated with mean normalized particle velocity. A mathematical model for particle action was in qualitative agreement with experimental results.
Defective bile salt biosynthesis and hydroxylation in mice with reduced cytochrome P450 activity (2012)

Hrn mice have strongly impaired bile salt synthesis and (re)hydroxylation capacity and are more susceptible to acute TDC-induced cholestasis. In this mouse model, a more-human BS pool can be instilled by BS feeding, without hepatic damage, which makes Hrn mice an attractive model to study the effects of human BS.
Development of a wide-tuning-range two-parallel-plate tunable capacitor for integrated wireless communication systems (2001)

This paper reports on the development of a micromachined parallel-plate tunable capacitor with a wide tuning range. Different from conventional two-parallel-plate tunable capacitors, this tunable capacitor consists of one suspended top plate and two fixed bottom plates. One fixed plate and the top plate form a variable capacitor, while the other one provides necessary electrostatic actuation. Among the fabricated prototype devices, a maximum controllable tuning range of 69.8%@1 MHz has been obtained experimentally, exceeding the theoretical limit (50%) of conventional two-parallel-plate tunable capacitors. A component quality factor (Q) of 30@5 GHz and a self-resonant frequency far beyond 5 GHz have been achieved. The fabrication process is compatible with the existing standard IC (integrated circuit) technology, which makes it suitable for integrated wireless communication applications. © 2001 John Wiley & Sons, Inc. Int J RF and Microwave CAE 11: 322–329, 2001.
Selective Potentiation of 5-Methyl-2-(1-Methylcyclohexyl)-4-Oxazoleacetic Acid (AD-4610) on Glucose-Induced Insulin Secretion (1988)

In the perfused pancreas from normal SD rats, AD-4610 (0.01-0.1 mM) potentiated biphasic insulin secretion induced by 7.5 mM of glucose. The concentration-response curve of insulin secretion to glucose was shifted leftwards with AD-4610 (0.1 mM) without altering either the threshold concentration of glucose to induce insulin secretion or the maximal insulin response to glucose, indicating increased sensitivity of the pancreatic B-cells to glucose. On the other hand, AD-4610 was 10-fold less effective in altering insulin secretion induced by arginine and glyceraldehyde. The effect of AD-4610 on insulin secretion and glucose metabolism was compared with that of tolbutamide in vivo. AD-4610 (100 mg/kg) potentiated insulin secretion induced by an intravenous glucose load, and also accelerated glucose metabolism without altering basal insulin secretion in normal rats. On the other hand, tolbutamide (20 mg/kg) increased basal insulin secretion, but slightly decreased glucose-induced insulin secretion. In yellow KK mice with hyperglycemia, AD-4610 (10-100 mg/kg) had a dose-dependent hypoglycemic action, but tolbutamide did not. Thus, AD-4610 stimulated insulin secretion in a glucose-dependent fashion and enhanced glucose metabolism in vivo. These results suggest that AD-4610 selectively potentiates glucose-induced insulin secretion by increasing the sensitivity of pancreatic B-cells to glucose and may be useful for treating human NIDDM through a different mechanism than that of tolbutamide.
Valorisation du lait de jument (2008)

Le lait de jument est doté de vertus nutritionnelles et diététiques intéressantes par rapport au lait de vache. Il est plus riche en vitamine C et en lactose, en substances antimicrobiennes (lactoferrine, lysozyme) et plus pauvre en matière grasse qui sont riches en acides gras essentiels. C’est également depuis toujours un aliment de remplacement idéal pour les enfants souffrant d’allergie au lait de vache. Il est aussi utilisé en cosmétique (savons, crèmes) et pour d’autres applications plus anecdotiques (bain, spa). Il peut donc constituer un débouché complémentaire intéressant pour la filière agricole de Franche-Comté qui dispose d’environ 3000 juments de race Comtoise utilisées pour le moment pour le loisir et la production de viande, la plupart du temps dans des élevages mixtes. La traite est toutefois contraignante (2 à 5 fois par jour en présence du poulain) et la mise en oeuvre du lait difficile (peu d’extrait sec, caséine peu coagulable en particulier). Sous l’impulsion de l’ANCTC (Association Nationale du Cheval de Trait Comtois) et de la Chambre Régionale d’Agriculture de Franche-Comté (CRAFC), un projet court depuis 2007, qui mobilise les moyens de recherche et d’expérimentation de l’UMT de Poligny . Deux pistes technologiques sont explorées à ce jour : (1) Coagulation enzymatique, fabrication de fromages à base de lait de jument et filtration membranaire (INRA-URTAL et ENIL-39), (2) Lait de consommation, fermentation et coagulation acide (ENIL-25). ACTILAIT assure une grande partie de la caractérisation chimique, biochimique et microbiologique du lait en collaboration avec l’INRA-URTAL. Le lait est produit dans 3 exploitations pilotes du Doubs et du Jura. Le projet est coordonné dans son ensemble par Patrice Dieudonné responsable Recherche et Développement à l’ENIL-25, par Sylvie Pochet (INRA-URTAL) en ce qui concerne les travaux effectués sur le site de Poligny et par Eric Notz pour ACTILAIT. Ces travaux bénéficient entre autres de fonds Eperon (provenant des recettes du PMU) et OSEO. Dans le cadre du pôle de compétitivité VITAGORA, des contacts ont été établis récemment avec la région Bourgogne qui dispose d’un potentiel de 250 juments de race Auxoise (dont 25 au Centre d’Elevage de Bierre-lès-Semur) pour tenter de développer des actions communes sur le thème nutrition–santé du lait de jument.
X‐Ray Structures of Two Xanthine Inhibitors Bound to PEPCK and N‐3 Modifications of Substituted 1,8‐Dibenzylxanthines. (2003)

Abstract For Abstract see ChemInform Abstract in Full Text.
Thorium and uranium M-shell x-ray production by 0.4–4.0 MeV protons and 0.4–6.0 MeV helium ions (2009)

M-shell x-ray production cross sections for thorium and uranium have been determined for protons of energies 0.4–4.0 MeV and helium ions of energies 0.4–6.0 MeV. The M-shell line and total M-shell x-ray production cross sections are compared to the predictions of the first Born approximation and ECUSAR ionization theory using recently recommended atomic parameters. Both theories are in good agreement with the data for protons and He ions above 1 MeV. The data of others for energies above 1 MeV protons on uranium, however, fall significantly under the present measurements. Below 1 MeV, with decreasing energy of these projectiles, the first Born approximation increasingly overestimates our measurements while the ECUSAR theory underestimates them to a similar degree. The same trends are seen versus the data of others.
Deep ultraviolet photodetectors grown by gas source molecular beam (2006)

Optically-based chemical and biological sensors require optoelectronic devices with specific emission and detection\nwavelength ranges. Semiconductor optoelectronic devices applicable to this sensing are of particular interest due to their\nlow power consumption, compact size, long lifetime, and low cost. We report the electrical and optical properties of\ndeep UV p-i-n photodiodes (PDs) based on short period superlattices (SPSLs) of AlN/AlGaN. All device and test\nstructures are grown by gas source molecular beam epitaxy with ammonia on sapphire and AlGaN/sapphire substrates.\nAlGaN/sapphire substrates were grown by stress controlled hydride vapor phase epitaxy (HVPE). The cutoff\nwavelength of PDs based on these SPSLs can be varied from 250 to 280 nm by changing the SPSL barrier/well\nthickness ratio. For mesa diodes with 150 μm diameter we obtain extremely low dark leakage current of ~ 3 pA/cm2,\nand high zero-bias resistance of ~ 6 × 1014 Ω. A cutoff wavelength of 247 nm is obtained for these devices with four\norders of magnitude rejection by 315 nm. We obtain a maximum responsivity of 60 mA/W.
9-(2,3,4-tri-O-benzyl-D-arabinopyranosyl)Purines (1969)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXT9-(2,3,4-tri-O-benzyl-D-arabinopyranosyl)PurinesAbelardo P. Martinez, William Wei Lee, and Leon GoodmanCite this: J. Med. Chem. 1969, 12, 6, 1125Publication Date (Print):November 1, 1969Publication History Published online1 May 2002Published inissue 1 November 1969https://pubs.acs.org/doi/10.1021/jm00306a050https://doi.org/10.1021/jm00306a050research-articleACS PublicationsRequest reuse permissionsArticle Views27Altmetric-Citations3LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
The biological role of oncogenes--insights from platelet-derived growth factor: Rhoads Memorial Award lecture. (1985)

No one in tumor biology can now be unaware of the overlap between growth factors and oncogenes. Many if not all oncogenes are now perceived as functional components of a mitogenic cascade which is normally controlled by growth factors. Some oncogenes function at the onset of this cascade by directing the synthesis of an automitogenic growth factor. Others function in the interior of the cascade by directing synthesis of a growth factor receptor or a structurally altered receptor derivative. Still other oncogenes appear to be mutated or rearranged homologues of genes the expression of which is normally induced by growth factors. Those of us working with platelet-derived growth factor (PDGF) take particular satisfaction in this new conceptual framework. It is within the molecular biology of PDGF that the overlap between growth factors and oncogenes is illustrated to its fullest and most tangible extent. An oncogene termed c-sis directs synthesis of a functional PDGF subunit. The PDGF receptor protein is in all probability encoded by a member of the src family of oncogenes. Formation of the PDGF:receptor complex stimulates expression of the c-myc and c-fos protooncogenes. My associates and I have devoted the past 10 years to the molecular biology of PDGF. Our studies on the control of the 3T3 cell cycle by PDGF contributed a pair of new jargon terms to the oncology literature--"competence" and "progression." We also had some input into the bottom end of the "oncogene hierarchy" displayed in Chart 1. The effort that we invested paid a pleasant dividend for me when, in the spring of 1984, the American Association for Cancer Research honored me with the Rhoads Memorial Award. What follows is an overview of the PDGF literature which is more anecdotal than comprehensive. My object is to show how the PDGF field moved from the level of whole animal biology, through biochemistry, down to molecular genetics in just 10 years time.
Translocator Protein (18 kDa) Polymorphism (rs6971) Explains <i>in-vivo</i> Brain Binding Affinity of the PET Radioligand [<sup>18</sup>F]-FEPPA (2012)

[(18)F]-FEPPA binds to the 18-kDa translocator protein (TSPO) and is used in positron emission tomography (PET) to detect microglial activation. However, quantitative interpretations of the PET signal with new generation TSPO PET radioligands are confounded by large interindividual variability in binding affinity. This presents as a trimodal distribution, reflecting high-affinity binders (HABs), low-affinity binder (LAB), and mixed-affinity binders (MABs). Here, we show that one polymorphism (rs6971) located in exon 4 of the TSPO gene, which results in a nonconservative amino-acid substitution from alanine to threonine (Ala147Thr) in the TSPO protein, predicts [(18)F]-FEPPA total distribution volume in human brains. In addition, [(18)F]-FEPPA exhibits clearly different features in the shape of the time activity curves between genetic groups. Testing for the rs6971 polymorphism may allow quantitative interpretation of TSPO PET studies with new generation of TSPO PET radioligands.
Residential data services via hybrid fiber-coax local access networks (1996)

The deployment of two-way broadband hybrid fiber-coax (HFC) local access networks will enable a wide variety of new communication services for consumers and small businesses. Interactive television, video-on-demand, video telephony, and other services focused on TV and video have attracted much attention. Broadband local access networks also offer compelling data-oriented services that support computers and other devices in homes and small businesses. This paper gives an overview of these new residential data services and applications, the technical challenges involved in their delivery, and architectures and key components of the required networking infrastructure.
Overproduction of <i>Thermus</i> sp. Strain T2 β-Galactosidase in <i>Escherichia coli</i> and Preparation by Using Tailor-Made Metal Chelate Supports (2003)

A novel thermostable chimeric beta-galactosidase was constructed by fusing a poly-His tag to the N-terminal region of the beta-galactosidase from Thermus sp. strain T2 to facilitate its overexpression in Escherichia coli and its purification by immobilized metal-ion affinity chromatography (IMAC). The poly-His tag fusion did not affect the activation, kinetic parameters, and stability of the beta-galactosidase. Copper-iminodiacetic acid (Cu-IDA) supports enabled the most rapid adsorption of the His-tagged enzyme, favoring multisubunit interactions, but caused deleterious effects on the enzyme stability. To improve the enzyme purification a selective one-point adsorption was achieved by designing tailor-made low-activated Co-IDA or Ni-IDA supports. The new enzyme was not only useful for industrial purposes but also has become an excellent model to study the purification of large multimeric proteins via selective adsorption on tailor-made IMAC supports.
Scaling Laws for Photoelectron Holography in the Midinfrared Wavelength Regime (2012)

Midinfrared strong-field laser ionization offers the promise of measuring holograms of atoms and molecules, which contain both spatial and temporal information of the ion and the photoelectron with subfemtosecond temporal and angstrom spatial resolution. We report on the scaling of photoelectron holographic interference patterns with the laser pulse duration, wavelength, and intensity. High-resolution holograms for the ionization of metastable xenon atoms by 7-16 μm light from the FELICE free electron laser are presented and compared to semiclassical calculations that provide analytical insight.
A Preplexity Based Cover Song Matching System For Short Length Queries. (2011)

[TODO] Add abstract here.
Approximate Modified Policy Iteration (2012)

Modified policy iteration (MPI) is a dynamic programming (DP) algorithm that\ncontains the two celebrated policy and value iteration methods. Despite its\ngenerality, MPI has not been thoroughly studied, especially its approximation\nform which is used when the state and/or action spaces are large or infinite.\nIn this paper, we propose three implementations of approximate MPI (AMPI) that\nare extensions of well-known approximate DP algorithms: fitted-value iteration,\nfitted-Q iteration, and classification-based policy iteration. We provide error\npropagation analyses that unify those for approximate policy and value\niteration. On the last classification-based implementation, we develop a\nfinite-sample analysis that shows that MPI's main parameter allows to control\nthe balance between the estimation error of the classifier and the overall\nvalue function approximation.\n
A Fundamental Limit on Antenna Gain for Electrically Small Antennas (2008)

A fundamental limit on an antenna's gain is derived and compared to measurements taken on a number of different antennas. First, a propagation formula applicable in both the near and far fields is developed, and that result is used to demonstrate that the gain of an antenna is limited by its electrical size.
Identification, regulation, and function of virulence factors (2002)

Alternatives to mammalian model systems. Virulence and essential gene identification. Global gene expression. Microarrays and proteomics. Bacterial perturbations of the eukaryotic cell cycle and apoptosis. Bacterial modification or exploitation of eukaryotic signal transduction. Type III secretion systems. Quarom sensing and gene regulation.
Predicting major depression in brain tumor patients (2002)

Very few studies have been performed utilizing DSM criteria to diagnose major depressive disorder (MDD) in adult brain tumor patients. This study aimed to diagnose MDD in this population using DSM-IV criteria.Eighty-nine adult brain tumor patients were examined in an ambulatory neuro-oncology clinic setting using a structured psychiatric interview which followed current DSM-IV diagnostic criteria for MDD. This sample was interviewed and evaluated on a one-time basis. The patients were referred for evaluation on a consecutive basis. Multiple regression was used to model critical independent variables to predict MDD.Twenty-eight percent of the sample (N=89) were found to have major depressive disorder using DSM-IV criteria. Key predictors of MDD included frontal region of tumor location (p=0.001), combined sadness and lack of motivation symptoms (p=0.0001), and family psychiatric history (p=0.006). The multiple regression models account for 37% of variance in predicting MDD (R(2)=0.37).A substantially higher incidence of MDD was found in this sample of adult brain tumor patients compared with other adult, ambulatory cancer patients previously evaluated with DSM criteria. The incidence of MDD was about triple that found in other published studies using DSM criteria.
Computational and Monte-Carlo Aspects of Systems for Monitoring Reliability Data (2010)

Monitoring plays a key role in today’s business environment, as large volumes of data are collected and processed on a regular basis. Ability to detect onset of new data regimes and patterns quickly is considered an important competitive advantage. Of special importance is the area of monitoring product reliability, where timely detection of unfavorable trends typically offers considerable opportunities of cost avoidance. We will discuss detection systems for reliability issues built by combining Monte-Carlo techniques with modern statistical methods rooted in the theory of Sequential Analysis, Change-point theory and Likelihood Ratio tests. We will illustrate applications of these methods in computer industry.