gebhart/patrepeval huggingface dataset:
Association constant of the sex-specific agglutinin in the yeast, Hansenula wingei (1970)

ADVERTISEMENT RETURN TO ISSUEPREVArticleAssociation constant of the sex-specific agglutinin in the yeast, Hansenula wingeiNeil Welling Taylor and William L. OrtonCite this: Biochemistry 1970, 9, 14, 2931–2934Publication Date (Print):July 7, 1970Publication History Published online1 May 2002Published inissue 7 July 1970https://pubs.acs.org/doi/10.1021/bi00816a027https://doi.org/10.1021/bi00816a027research-articleACS PublicationsRequest reuse permissionsArticle Views17Altmetric-Citations9LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
LABORATORY (1933)

LABORATORY A YEAST EXTRACT MEDIUM FOR DETERMINING THE BACTERIAL CONTENT OF MILK BY THE PLATE METHOD * E. D. Devereux, and J. L. Etchells CopyRight*Journal Article No. 121 (n.s.) from the Michigan Agricultural Experiment Station. https://doi.org/10.2105/AJPH.23.2.149 Published Online: August 29, 2011
Stable and Selective Recognition of Three Base Pairs in the Parallel Triple‐Helical DNA Binding Motif (2004)

Modifying bases in parallel-triplex-forming oligonucleotides with a 2′-O-aminoethyl backbone enabled an extended DNA triplex recognition code to be developed for use in the control of gene expression. Removal of the oxygen atom at C4 of thymine transforms a donor/acceptor base into a double acceptor base and redirects recognition from A–T to strong and highly selective C–G recognition (see scheme).
Attacks and countermeasures in communications and power networks (2014)

The threat of malicious network attacks has become significant ever since networking became pervasive in our life. When adversaries have enough control over the network measurements and control procedures, the effect of attacks can be as detrimental as the breakdown of the whole network operations. This dissertation studies possible adversarial effects under certain protection strategy, the conditions under which attacks can be detected, and protection strategies to render attacks detectable. Specifically, attacks on two types of networks are considered: communications networks and power networks.
First, we consider an attack on communications networks, where a pair of nodes are suspected to belong to the chain of compromised nodes used by the adversary. If the pair belongs to the compromised chain, it forwards attack packets along the chain, and thus there should exist an information flow between the pair. Detection of an information flow based on node transmission timings is formulated as a binary composite hypothesis testing. An unsupervised and nonparametric detector with linear complexity is proposed and tested with real-world TCP traces and MSN VoIP traces. The detector is proved to be consistent for a class of nonhomogeneous Poisson processes.
Secondly, the topology attack on power networks is studied. In a so-called man-in-the-middle topology attack, an adversary alters data from certain meters and network switches to mislead the control center with an incorrect network topology while avoiding detection by the control center. A necessary and sufficient condition for the existence of an undetectable attack is obtained, and countermeasures to prevent undetectable attacks are presented. It is shown that any topology attack is detectable if a set of meters satisfying a certain branch covering property are protected from adversarial data modification. The proposed attacks are tested with IEEE 14-bus and IEEE 118-bus system, and their effect on real-time locational marginal pricing is examined.
Lastly, a new attack mechanism aimed at misleading the power system control center about the source of data attacks is proposed. As a man-in-the-middle state attack, a data framing attack is proposed to exploit the bad data detection and identification mechanisms at the control center. In particular, the proposed attack frames normal meters as sources of bad data and causes the control center to remove useful measurements from the framed meters. The optimal design of data framing attack is formulated as a quadratically constrained quadratic program (QCQP). It is shown that the proposed attack is capable of perturbing the power system state estimate by an arbitrary degree using only half of the critical measurements. Implications of this attack on power system operations are discussed, and the attack performance is evaluated using benchmark systems.
Antibacterial Efficacy of Benzoyl Peroxide in Phospholipid Liposomes (1999)

A BPO formulation in phospholipid liposomes may represent an improvement of the conventional external BPO treatment of acne.
β<sub>2</sub>‐Adrenoceptors, NADPH oxidase, ROS and p38 MAPK: another ‘radical’ road to heart failure? (2010)

Persistent activation of the cardiac β-adrenergic system may contribute to the pathogenesis of congestive heart failure. Both β₁- and β₂-adrenoceptors are known to mediate these noxious effects, yet the β₁-adrenoceptor-PKA axis has received greater attention with less information available on β₂-adrenoceptor driven pathways. In the present issue, Xu and colleagues provide new evidence, showing that β₂-adrenoceptor over-expression leads to increased reactive oxygen species (ROS) emission, mainly caused by up-regulation of reduced nicotinamide adenine dinucleotide phosphate oxidase (Nox) 2 and 4. Increase in ROS levels is accompanied by p38 mitogen-activated protein kinase activation, fibrosis, apoptosis and cardiac dysfunction. Both Nox inhibition and administration of the antioxidant N-acetyl cysteine prevent these adverse effects. Interestingly, antioxidant treatment also prevents the increase in Nox expression, suggesting that β₂-adrenoceptor stimulation triggers a vicious cycle eventually amplified by both Nox isoforms. The possible existence of a circuitry to enhance ROS signalling and detrimental consequences on myocardial remodelling are also discussed, in light of the recent description of intracellular localization of Nox4.
Genetic changes in breast cancer detected by comparative genomic hybridisation (2000)

Breast cancer is characterised by a number of genetic aberrations. Our purpose was to use comparative genomic hybridisation (CGH) to screen breast carcinomas for copy number changes: 44 ductal and 8 lobular carcinomas were studied and a large number of genetic aberrations identified. Many of these showed similarity to previous CGH results, however, a number of loci not previously shown to have undergone frequent change were identified. This included copy number gains affecting chromosomes 1p, 4q, 5q, 6q and 13q. Furthermore, we have identified 2 regions of copy number change, the gain on 5p and deletion of 16q, which correlated with lobular carcinomas. Our results highlight several areas of the genome that may be important in the molecular genetics of breast cancer. Int. J. Cancer 86:494–500, 2000. © 2000 Wiley-Liss, Inc.
A Direct Catalytic Asymmetric Mannich-type Reaction via a Dinuclear Zinc Catalyst:  Synthesis of Either <i>anti</i>- or <i>s</i><i>yn</i>-α-Hydroxy-<i>β</i>-Amino Ketones (2006)

The use of imines bearing a hydrolyzable nitrogen substituent in direct asymmetric Mannich reactions with alpha-hydroxyketones is developed. Previous work focused on the use of N-arylimines or nonenolizable imines, and the latter with only methoxy-substituted alpha-hydroxyacetophenones. Using a dinuclear catalyst devised from 2,6-di-(S)-2'-diphenylhydroxymethylpyrrolidino-N-methyl)-4-methylphenol and diethylzinc, a broad array of hydroxyacetylated aromatics, including phenyl, 2-furyl, 1-naphthyl, and 2-naphthyl, react well. In addition, the reactions focused on the use of enolizable imines. With the N-diphenylphosphinoyl, the reactions are anti selective with enantiomeric excesses ranging from 83 to 99%, except for the reaction of the 2-methoxy-2'-hydroxyacetylbenzene. With the N-Boc-imines, the reactions were syn selective with enantiomeric excesses from 90 to 94%. The dependence of the diastereoselectivity on the nature of the N-substituent presumably arises from the steric demands of the diphenylphosphinoyl group.
Typing of LaCrosse, snowshoe hare, and Tahyna viruses by analyses of single-strand conformation polymorphisms of the small RNA segments (1995)

Single-strand conformation polymorphism analysis was developed to differentiate the small RNA segments of three California serogroup bunyaviruses. The small RNA segments of La Crosse, snowshoe hare, and Tahyna viruses were reverse transcribed and PCR amplified. The cDNAs were then denatured, rapidly chilled to promote intrastrand reassociation, separated electrophoretically on a nondenaturing gel at room temperature, and silver stained. The resulting single-strand conformation polymorphism patterns were specific for the respective viruses. This molecular technique offers great potential for virus typing and taxonomic studies.
<title>Sensitometry At Low X-Ray Energies</title> (1981)

Inverse-square sensitometry for low kVp techniques is limited by air attenuation and beam hardening. It is thus difficult to obtain accurate H and D curves for mammographic screen-film combinations at technique factors used clinically. Methods are described for the determination of characteristic curves at low x-ray energies which provide composite intensity-scale curves using small changes in source-to-receptor distance and concomitant changes in either exposure time, beam attenuation or kVp. H and D curves obtained at low kVp's using the various sensitometric approaches are compared with those obtained using inverse-square sensitometry; the relative merits of the different methods are discussed.
M2GSNet: Multi-Modal Multi-Task Graph Spatiotemporal Network for Ultra-Short-Term Wind Farm Cluster Power Prediction (2020)

Ultra-short-term wind power prediction is of great importance for the integration of renewable energy. It is the foundation of probabilistic prediction and even a slight increase in the prediction accuracy can exert significant improvement for the safe and economic operation of power systems. However, due to the complex spatiotemporal relationship and the intrinsic characteristic of nonlinear, randomness and intermittence, the prediction of regional wind farm clusters and each wind farm’s power is still a challenge. In this paper, a framework based on graph neural network and numerical weather prediction (NWP) is proposed for the ultra-short-term wind power prediction. First, the adjacent matrix of wind farms, which are regarded as the vertexes of a graph, is defined based on geographical distance. Second, two graph neural networks are designed to extract the spatiotemporal feature of historical wind power and NWP information separately. Then, these features are fused based on multi-modal learning. Third, to enhance the efficiency of prediction method, a multi-task learning method is adopted to extract the common feature of the regional wind farm cluster and it can output the prediction of each wind farm at the same time. The cases of a wind farm cluster located in Northeast China verified that the accuracy of a regional wind farm cluster power prediction is improved, and the time consumption increases slowly when the number of wind farms grows. The results indicate that this method has great potential to be used in large-scale wind farm clusters.
The Challenge of Maintaining Stormwater Control Measures: A Synthesis of Recent Research and Practitioner Experience (2018)

The methods for properly executing inspection and maintenance of stormwater control measures are often ambiguous and inconsistently applied. This paper presents specific guidelines for inspecting and maintaining stormwater practices involving media filtration, infiltration, ponds, and permeable pavements because these tend to be widely implemented and often unsatisfactorily maintained. Guidelines and examples are based on recent scientific research and practitioner experience. Of special note are new assessment and maintenance methods, such as testing enhanced filtration media that targets dissolved constituents, maintaining proper vegetation coverage in infiltration practices, assessing phosphorus release from pond sediments, and the development of compressed impermeable regions in permeable pavements and their implications for runoff. Inspection and maintenance examples provided in this paper are drawn from practical examples in Northern Midwest USA, but most of the maintenance recommendations do not depend on regional characteristics, and guidance from around the world has been reviewed and cited herein.
Liquid Crystal Polymers: A Small Angle Neutron Scattering Study (1988)

Abstract One reports Small Angle Neutron Scattering (SANS) studies on mesogenic comb-like polymers. One has drawn attention on different polymethacrylates specially in nematic phase. A way to determine the conformation of these polymers, consists to measure their quadratic sizes by the labelling method. One has also tested this method in function of the molecular length of a LC-polysiloxane. It appears that wathever the chemical species, the backbone of polymers prefer to be perpendicular to their mesogenic groups in the smectic phase. The situation is less simple in the nematic phase.
Climate-induced larch growth response within the central Siberian permafrost zone (2015)

Aim: estimation of larch ( Larix gmelinii ) growth response to current climate changes. Location: permafrost area within the northern part of Central Siberia (∼65.8°N, 98.5°E). Method: analysis of dendrochronological data, climate variables, drought index SPEI, GPP (gross primary production) and EVI vegetation index (both Aqua/MODIS satellite derived), and soil water content anomalies (GRACE satellite measurements of equivalent water thickness anomalies, EWTA). Results : larch tree ring width (TRW) correlated with previous year August precipitation ( r = 0.63), snow accumulation ( r = 0.61), soil water anomalies ( r = 0.79), early summer temperatures and water vapor pressure ( r = 0.73 and r = 0.69, respectively), May and June drought index ( r = 0.68–0.82). There are significant positive trends of TRW since late 1980 s and GPP since the year 2000. Mean TRW increased by about 50%, which is similar to post-Little Ice Age warming. TRW correlated with GPP and EVI of larch stands ( r = 0.68–0.69). Main conclusions: within the permafrost zone of central Siberia larch TRW growth is limited by early summer temperatures, available water from snowmelt, water accumulated within soil in the previous year, and permafrost thaw water. Water stress is one of the limiting factors of larch growth. Larch TRW growth and GPP increased during recent decades.
SPEPlip: the detection of signal peptide and lipoprotein cleavage sites (2003)

It can be accessed through the web page at http://gpcr.biocomp.unibo.it/predictors/
Radiation therapy with concomitant and adjuvant cisplatin and paclitaxel in high-risk cervical cancer: long-term follow-up. (2006)

The combination of paclitaxel and cisplatin appears efficacious in "high-risk" cervical cancer patients. Hematologic toxicity was common but tolerable. Long-term survival was common in these patients, however late toxicity was significant. This regimen should be investigated in collaborative phase III trials.
Direct assessment of series resistance in thin film solar cells utilizing electroluminescence (2010)

The direct assessment method of series resistance of transparent conductive oxide (TCO) in thin film cells was proposed utilizing the line scan analysis of electroluminescence (EL) emission intensity. The line scan profile of EL intensity represents the series resistance in TCO, and the quantitative information can be obtained by simulating the line intensity profiles along the injection edge to the collection edge. The non-destructive assessment method in as-fabricated cells will be useful in designing the optimized structure to get high efficiency.
Increased Shear Stress Leads to Differential Release of Endothelin and ATP from Isolated Endothelial Cells from 4- and 12-Month-Old Male Rabbit Aorta (1992)

Freshly isolated thoracic aortic endothelial cells from 4- and 12-month-old male rabbits were exposed to two periods of increased flow rate and the levels of ATP, endothelin (ET) and arginine vasopressin (AVP) released into the perfusate were measured. The rapid, significant release of ATP and ET with increased flow from cells isolated from 12-month-old rabbits was not seen when cells isolated from 4-month-old rabbits were exposed to the same conditions. Increased flow did not stimulate AVP release from cells from either age group. Basal release with low flow also differed in endothelial cells from 4-month-old compared to 12-month-old rabbits; thus in 4-month preparations basal release of AVP was greater, that of ET was smaller, while that of ATP was unchanged relative to 12-month preparations. Immunohistochemical studies showed that almost half as many endothelial cells isolated from 4-month-old rabbits were immunoreactive to ET and AVP compared to cells isolated from 12-month-old animals. It is suggested that the endothelial contribution to the control of vascular tone in rabbit thoracic aorta changes during ageing.
<title>Potential of a beryllium x-ray lens</title> (1997)

The use of refractive lenses for focusing x-ray beams has been the subject of publications since the early 1980s. Detailed calculations have been made for different shapes for the refractive lens: cylindrical, spherical, parabolic, and for a Fresnel-type refractive lens. The main drawback to the use of a single refractive lens to focus x-rays is that the index of refraction (n equals 1 - (delta) ) is very close to 1, which results in a lens with a very long focal length. Recently Snigerov and others have suggested and experimentally demonstrated, using cylindrical-shaped lenses, that this problem of long focal lengths can be overcome by using many lenses in series. Each lens refracts the photon through a small angle, but the sum of these sequential changes in direction can be moderately large. This increase in effective refraction angle reduces the focal length of the lens to a few meters or less and makes the multi-element lens a much more useful instrument for focusing x-rays. This paper, annualizes the expected performance of a lens consisting of a series of aligned hollow spheres in a beryllium substrate. The use of hollow spheres rather than hollow cylinders produces focusing of the x rays into a small focal spot in contrast to the single-directional focusing of the hollow cylinders, which produces a line focus. The use of beryllium as the substrate results in lower photo cross sections for both scattering and absorption relative to the value of the refractive index as compared to higher-Z materials and results in higher transmission values than for lenses with thin webs between the lens elements without distorting the surfaces of the neighbor lens element. This plus beryllium's low density, keep the absorption and scattering in the web at a minimum. The calculations suggest that one will be able to make Be lenses with short focal lengths (1 to 2 m) with useable transmissions (10 to 30%). Two multi-element lenses have been constructed: one with 20 1-mm-diameter hollow spheres in an aluminum substrate, and one with 50 hollow spheres, 1 mm in diameter, in a beryllium substrate. Some construction details and calculations of the expected performance, are given for these two multi-element lenses.
Structurally integrated phased arrays (2011)

This paper will discuss the benefits and challenges of integrating large structural apertures or antennas into aircraft structure. <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">12</sup> Current generation parasitic (non-load bearing) antennas are limited in size and installation location by vehicle airframe and flight characteristics. Typical mission scope is adversely impacted by the weight and aerodynamic drag associated with surface mounted fairings, blades, and radomes. These features reduce electrical/structural efficiency by limiting payload, range and overall RF performance. Structurally integrating antenna apertures in non-traditional locations (e.g., doors, wing skins, and fuselage panels) could greatly improve mission capability and ISR effectiveness on a wide array of air, water, ground and space-based assets. Structural integration of radiators and associated electrical components can result in reductions in aerodynamic drag count, significant parasitic weight, and total system volume. Such integrated apertures have the potential to enhance the number and nature of sensor functions above and beyond what is currently provided by traditional aperture radome systems. Boeing, in conjunction with Air Force Research Labs, has been developing a novel structurally integrated phased array concept. The structural phased array design space includes wing, door, and fairing integration. To address the feasibility of integrating structural arrays into this design space, a series of analyses, coupons, and tests were performed. Finite element modeling (FEM) was performed to configure the array to meet structural design requirements under various load conditions. Coupons were fabricated to address the manufacturability of the structural arrays. Structural tests were performed to verify the modeling and provide a check for the continuity of the electronics. The results from the structural tests confirm the compatibility of structural arrays within the wing, doors, and fairing structures to meet structural and Radio Frequency (RF) requirements.