gebhart/patrepeval huggingface dataset:
Virtual bronchoscopic approach for combining 3D CT and endoscopic video (2000)

To improve the care of lung-cancer patients, we are devising a diagnostic paradigm that ties together three-dimensional (3D) high-resolution computed-tomographic (CT) imaging and bronchoscopy. The system expands upon the new concept of virtual endoscopy that has seen recent application to the chest, colon, and other anatomical regions. Our approach applies computer-graphics and image-processing tools to the analysis of 3D CT chest images and complementary bronchoscopic video. It assumes a two-stage assessment of a lung-cancer patient. During Stage 1 (CT assessment), the physician interacts with a number of visual and quantitative tools to evaluate the patient's 'virtual anatomy' (3D CT scan). Automatic analysis gives navigation paths through major airways and to pre-selected suspect sites. These paths provide useful guidance during Stage-1 CT assessment. While interacting with these paths and other software tools, the user builds a multimedia Case Study, capturing telling snapshot views, movies, and quantitative data. The Case Study contains a report on the CT scan and also provides planning information for subsequent bronchoscopic evaluation. During Stage 2 (bronchoscopy), the physician uses (1) the original CT data, (2) software graphical tools, (3) the Case Study, and (4) a standard bronchoscopy suite to have an augmented vision for bronchoscopic assessment and treatment. To use the two data sources (CT and bronchoscopic video) simultaneously, they must be registered. We perform this registration using both manual interaction and an automated matching approach based on mutual information. We demonstrate our overall progress to date using human CT cases and CT-video from a bronchoscopy- training device.© (2000) COPYRIGHT SPIE--The International Society for Optical Engineering. Downloading of the abstract is permitted for personal use only.
Microbial hydroxylation of the herbicide N-(3,4-dichlorophenyl)methacrylamide (dicryl) (1973)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTMicrobial hydroxylation of the herbicide N-(3,4-dichlorophenyl)methacrylamide (dicryl)Peter R. Wallnoefer, Steve Safe, and Otto HutzingerCite this: J. Agric. Food Chem. 1973, 21, 3, 502–504Publication Date (Print):May 1, 1973Publication History Published online1 May 2002Published inissue 1 May 1973https://pubs.acs.org/doi/10.1021/jf60187a047https://doi.org/10.1021/jf60187a047research-articleACS PublicationsRequest reuse permissionsArticle Views35Altmetric-Citations7LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Gene transfer and transposition mutagenesis in Streptomyces roseosporus: mapping of insertions that influence daptomycin or pigment production (1996)

Streptomyces reseosporus, the producer of the cyclic lipopeptide antibiotic daptomycin, was shown to be a suitable host for molecular genetic manipulation. S. roseosporus does not appear to express significant restriction barriers based upon bacteriophage plaque formation studies. Plasmid DNA can be introduced into S. roseosporus by bacteriophage-FP43-mediated transduction and by conjugation from Escherichia coli. The streptomycete transposons Tn5096 and Tn5099, derived from IS493, transpose in S. roseosporus, and Tn5099-induced transposition mutants altered in the production of daptomycin, red pigment or black pigment were identified, and mapped to Dral and Asnl fragments. Three auxotrophic mutations (argB1, ade-1 and metB1) were identified among 100 individual Tn5096 insertions. Alignment and physical mapping of several Tn5099 insertions in Dral-E and Asnl-B fragments was facilitated by the presence of Dral and Asnl cleavage sites in Tn5099.
Effects of Verapamil and Atenolol on Exercise Tolerance in 5,000 m Cross-Country Running: A Double-Blind Cross-Over Study in Normal Humans (1990)

The effects on exercise tolerance of 7-day treatment with a calcium channel blocker, verapamil 160 mg twice daily (b.i.d.), and a beta 1-selective blocker, atenolol 50 mg b.i.d., were compared in 10 healthy and physically active young subjects in 5,000-m cross-country running at high intensity. The study was a double-blind cross-over trial. Comparison was made with a single-blind placebo as well. Performance time was measured every 1,000 m in seven 5,000-m runs, in which subjects were instructed to keep to a constant fatigue perception (Borg scale rating). Both drugs significantly (p = 0.001) increased the performance time over the first 1,000 m as compared with placebo. However, running time after 1,000, 2,000, and 3,000 m was prolonged significantly less (p less than 0.05) by verapamil than by atenolol. For the entire 5,000-m run, atenolol caused a significant increase (p = 0.001) in mean running time by 1 min 34 s (i.e., 7.5%; 95% confidence interval 48 s to 2 min 21 s) as compared with placebo, whereas verapamil caused no significant change (+46 s).
Microbial Requirements for Optimal Surfactant Degradation in a Denitrifying, Fixed-Bed Bioreactor (2001)

<div class="htmlview paragraph">Ground studies at Kennedy Space Center were conducted to determine microbial requirements of the Immobilized Microbe Microgravity Water Processing System (IMMWPS), a denitrifying, fixed-bed reactor designed for Shuttle flight-testing. The reactor was operated with a simulated graywater “waste stream” containing the surfactant Igepon TC-42<sup>TM</sup> as the sole carbon source. Experiments were conducted to determine the effect of hydraulic retention time (HRT) and feed nutrient composition on surfactant degradation. The source of inoculum as well as procedure for inoculating the reactor was also examined. A complete nutrient mix in the feed formulation was required for sustained Igepon degradation throughout the reactor runs at the short (1.4 days) and intermediate (1.9 days) hydraulic retention time (HRT), regardless of inoculum source.</div>
Is hormonal treatment efficacious in the management of ovarian cysts in women with histories of endometriosis? (1996)

In a controlled, randomized study, we evaluated the effectiveness of various hormonal regimens in treating 70 women (mean age 34.7 +/- 5.7 years) who had unilateral of bilateral ovarian cysts presumed to be physiological (functional) and a history of endometriosis. The patients were assigned randomly to one of the following groups: group I (control), no treatment; group II, oral contraceptives (35 micrograms ethinyl oestradiol and 1 mg norethindrone); group III, oral contraceptives (50 micrograms ethinyl oestradiol and 1 mg norethindrone); group IV, danazol 800 mg/day. Serum CA-125 concentrations were measured in 32 women. All medications were taken continuously for 6 weeks. Subjects were re-evaluated by pelvic examination and transvaginal ultrasound. Those with persistent cysts were offered diagnostic and possible operative laparoscopy. As 11 patients did not complete the study and five did not follow-up, the final study population comprised 54 women. At 6 weeks follow-up, complete resolution of cysts was found in: group I, 12 out of 18 (66.7%); group II, five out of none (55.6%); group III, eight out of 14 (57.1%); and group IV, seven out of 13 (53.9%). Two of the 22 women with persistent cysts opted for 6 weeks further medical therapy and achieved complete resolution; 19 underwent laparoscopy, and one was lost to follow-up. All laparoscopic findings revealed benign masses. We found no statistically significant effect when hormonal treatment was compared with expectant management. There was no correlation between serum CA-125 concentrations and the persistence of resolution of cysts.
Model-based sparse component analysis for reverberant speech localization (2014)

In this paper, the problem of multiple speaker localization via speech separation based on model-based sparse recovery is studies. We compare and contrast computational sparse optimization methods incorporating harmonicity and block structures as well as autoregressive dependencies underlying spectrographic representation of speech signals. The results demonstrate the effectiveness of block sparse Bayesian learning framework incorporating autoregressive correlations to achieve a highly accurate localization performance. Furthermore, significant improvement is obtained using ad-hoc microphones for data acquisition set-up compared to the compact microphone array.
Up-Regulation of CCR1 and CCR3 and Induction of Chemotaxis to CC Chemokines by IFN-γ in Human Neutrophils (1999)

Abstract Human neutrophils (polymorphonuclear leukocytes; PMN) respond to some CXC chemokines but do not migrate to CC chemokines. Recent work has shown that chemokine receptors can be modulated by inflammatory cytokines. In this study, the effect of IFN-γ, a prototypic Th1 cytokine, on chemokine receptor expression in PMN was investigated. IFN-γ caused a rapid (∼1 h) and concentration-dependent increase of CCR1 and CCR3 mRNA. The expression of CCR2, CCR5, and CXCR1–4 was not augmented. IFN-γ-treated PMN, but not control cells, expressed specific binding sites for labeled monocyte-chemotactic protein (MCP)-3 and migrated to macrophage-inflammatory protein (MIP)-1α, RANTES, MCP-3, MIP-5/HCC2, and eotaxin. 7B11, a mAb for CCR3, inhibited the chemotactic response of IFN-γ-treated PMN to eotaxin, and aminoxypentane-RANTES blocked PMN migration to RANTES. These results suggest that the selectivity of certain chemokines for their target cells may be altered by cytokines produced within an inflammatory context. Since PMN may play a role in orienting immunity toward Th1 responses, it is possible to speculate that IFN-γ not only promotes Th1 differentiation directly, but also reorients the functional significance of Th2 effector cytokines by broadening the spectrum of their action to include PMN.
Ongoing Telmisartan Alone and in Combination with Ramipril Global Endpoint Trial (2008)

The angiotensin-receptor blocker telmisartan is equally effective in reducing cardiovascular risk as the angiotensin-converting enzyme inhibitor ramipril in patients with vascular disease or high-risk diabetes. However, the combination is no more effective than either drug alone and causes more side effects according to results from the ONTARGET Trial.
Boric Acid in the Aqueous Carboxylation of m-Aminophenol to p-Aminosalicylic Acid<sup>1</sup> (1958)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTBoric Acid in the Aqueous Carboxylation of m-Aminophenol to p-Aminosalicylic Acid1LEONARD DOUB, J. A. SCHAEFER, O. L. STEVENSON, C. T. WALKER, and J. M. VANDENBELTCite this: J. Org. Chem. 1958, 23, 10, 1422–1424Publication Date (Print):October 1, 1958Publication History Published online1 May 2002Published inissue 1 October 1958https://pubs.acs.org/doi/10.1021/jo01104a005https://doi.org/10.1021/jo01104a005research-articleACS PublicationsRequest reuse permissionsArticle Views354Altmetric-Citations6LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Preparation and structure of a six-coordinate cobalt(III) complex containing the quinquedentate ligand N,N'-bis(salicylidene)dipropylenetriamine (1974)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPreparation and structure of a six-coordinate cobalt(III) complex containing the quinquedentate ligand N,N'-bis(salicylidene)dipropylenetriamineThomas J. Kistenmacher, Luigi G. Marzilli, and Patricia A. MarzilliCite this: Inorg. Chem. 1974, 13, 9, 2089–2093Publication Date (Print):September 1, 1974Publication History Published online1 May 2002Published inissue 1 September 1974https://pubs.acs.org/doi/10.1021/ic50139a009https://doi.org/10.1021/ic50139a009research-articleACS PublicationsRequest reuse permissionsArticle Views72Altmetric-Citations11LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
Polarity determination of single-crystal epitaxial layers by x-ray diffraction (1989)

The anomalous scattering of x rays has been used to determine the polarity of single-crystal epitaxial layers, as grown on the substrate material. The method relies on the breakdown of Friedel’s law in noncentrosymmetric structures and is particularly effective when there exists a large difference between the values of the imaginary anomalous dispersion correction, f″, for the respective atomic species. The method is nondestructive and measurements are taken from only one side of the sample (the side with the epitaxial layer).
Positioning control of direct drive robot with two-degree-of-freedom compensator (2002)

Recently, a disturbance observer based controller has been widely used in the industrial world because of its simplicity. However, this method depends on the intuitive approach in determining the disturbance estimation filter, and therefore, more systematic approach is desired. In this paper, we first combine the generalized compensator and the disturbance observer based controller by clarifying the internal structure of the generalized 2-degree-of-freedom (DOF) compensator. Secondly, based on the clarified structure, we derive a robust stability condition, and propose the design algorithm of a free parameter taking into account the condition. The proposed design algorithm is easy to implement and, as a result, we obtain a lower order free parameter than that of the conventional design algorithm. Thirdly, we show by adopting an appropriate coprime factorization that the clarified structure can also be regarded as an extended version of the conventional PD compensator. Finally, we apply the proposed algorithm to a positioning control of a 3-DOF direct drive robot, and show some experimental results to verify the effectiveness of the proposed algorithm.
Superelectrophilic Amidine Dications: Dealkylation by Triflate Anion (2012)

Superelektrophile: Formamide, die bei der Behandlung mit Trifluormethansulfonsäureanhydrid (Tf2O) superelektrophile Amidin-Dikationen ergeben, wurden entworfen. Die Dikationen waren so elektrophil, dass sie in situ durch das Triflat-Anion desalkyliert wurden (siehe Schema). Mithilfe von DFT-Rechnungen wurden die mechanistischen Details der Desalkylierung ermittelt.
Distributed Adaptive Optimization in Virtual Body Assembly (2005)

The Digital Body Development System (DBDS) is 4 year project to shorten the time to launch vehicles by improving the launch problem solving process. The project is based on two concepts: virtual functional build and an intelligent agent based decision support system. This paper presents a novel architecture for the decision support system that streamlines the launch process through the integration of a virtual assembly simulation, problem identification, and solution generation and evaluation. Following the virtual functional build process, the architecture deploys a number of multi-agent systems to provide system functionality, such as problem knowledge retrieval, solution generation, modification, and evaluation. The architecture has been implemented and will be explained on a simple 2-D door model and a casebase of 100 cases. Results show that the DBDS can find the correct solution much faster than a random search and can automatically implement and evaluate the solution.
Bacillus licheniformis FMCH001 Increases Water Use Efficiency via Growth Stimulation in Both Normal and Drought Conditions (2020)

Increasing agricultural losses due to biotic and abiotic stresses caused by climate change challenge food security worldwide. A promising strategy to sustain crop productivity under conditions of limited water availability is the use of plant growth promoting rhizobacteria (PGPR). Here, the effects of spore forming <i>Bacillus licheniformis</i> (FMCH001) on growth and physiology of maize (<i>Zea mays</i> L. cv. Ronaldinho) under well-watered and drought stressed conditions were investigated. Pot experiments were conducted in the automated high-throughput phenotyping platform PhenoLab and under greenhouse conditions. Results of the PhenoLab experiments showed that plants inoculated with <i>B. licheniformis</i> FMCH001 exhibited increased root dry weight (DW) and plant water use efficiency (WUE) compared to uninoculated plants. In greenhouse experiments, root and shoot DW significantly increased by more than 15% in inoculated plants compared to uninoculated control plants. Also, the WUE increased in FMCH001 plants up to 46% in both well-watered and drought stressed plants. Root and shoot activities of 11 carbohydrate and eight antioxidative enzymes were characterized in response to FMCH001 treatments. This showed a higher antioxidant activity of catalase (CAT) in roots of FMCH001 treated plants compared to uninoculated plants. The higher CAT activity was observed irrespective of the water regime. These findings show that seed coating with Gram positive spore forming <i>B. licheniformis</i> could be used as biostimulants for enhancing plant WUE under both normal and drought stress conditions.
ChemInform Abstract: Reversible Hydrogen Storage via Titanium‐Catalyzed LiAlH<sub>4</sub> and Li<sub>3</sub>AlH<sub>6</sub>. (2002)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
The 5.8S RNA gene sequence and the ribosomal repeat of<i>Schizosaccharomyces pombe</i> (1982)

We have characterized the rRNA gene repeat in Schizosaccharomyces pombe. This repeat, which does not contain the 5S RNA gene, is found in a 10.4 kb HindIII DNA fragment. We have determined the nucleotide sequences of the S. pombe 5.8S RNA gene and intergenic spacers from two different 10.4 kb DNA fragments. Analysis of isolated total cellular 5.8S RNA revealed the presence of eight species of 5.8S RNA, differing in the number of nucleotides at the 5'-end. The eight 4.8S RNA species vary in length from 158 to 165 nucleotides. Apart from the heterogeneity observed at the 5'-end, the sequence of the eight 5.8S RNA species appears to be identical and is the same sequence as coded for by the 5.8S genes. The gene sequence shows great homology to the 5.8S RNA genes or S. cerevisiae and N. crassa. Most of the base differences are confined to the highly variable stem though to be involved in co-axial helix stacking with the 25S RNA, where base pairing is nearly identical despite the sequence differences. Secondary structure models are examined in light of 5.8S RNA oligonucleotide conservation across species from yeasts to higher eukaryotes.
Accelerated onset of uterine tumors in transgenic mice with aberrant expression of the estrogen receptor after neonatal exposure to diethylstilbestrol (1997)

The role of estrogen and the estrogen receptor (ER) in the induction and promotion of tumors was investigated by using transgenic MT-mER mice, which overexpress the ER. It was hypothesized that because of this abnormal expression of the ER, the reproductive-tract tissues of the MT-mER mice may be more susceptible to tumors after neonatal exposure to the potent synthetic estrogen diethylstilbestrol (DES). Normally non-estrogen responsive tissues that may have expressed ER as a result of the transgene were also studied for DES-induced tumors. Wild-type and MT-mER littermates were treated with 2 micrograms/pup/d DES 1-5 d after birth and then killed at 4, 8, 12, and 18 mo of age. The DES-treated MT-mER mice demonstrated a significantly higher incidence of uterine adenocarcinoma at 8 mo (73%) than the DES-treated wild-type mice (46%). The tumors of the MT-mER mice were often more aggressive than those in the wild-type animals. These tumors were also preceeded at 4 mo by a significantly higher incidence of the preneoplastic lesion atypical hyperplasia in the MT-mER mice (26% compared with 0% in the wild-type mice). Other DES-induced abnormalities were observed at equal rates in the wild-type and MT-mER mice. Although no tumors were observed in untreated wild-type females, a single untreated MT-mER female had uterine adenocarcinoma at 18 mo. These data indicate that the level of ER present in a tissue may also be a determining factor in development of estrogen-responsive tumors.
ChemInform Abstract: Supramolecular Aggregation of m‐Nitrobenzoic Acid by C—H×××O and O—H×××O Hydrogen Bondings in the Crystalline Charge‐Transfer Complexes with Aromatic Hydrocarbons. (2000)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
A Simple and Facile Total Synthesis of Sesquiterpene, Cuparene by Using Furan Derivatives (1979)

Abstracts -5-Methyl-2-(4-methylbenzy1)furan ( ) obtained from the condensation of 2-lithio-5-methylfuran with 4-methylbenzvl bromide was converted into 3-methyl-2-(4-methylbenzy1~cyclopenten- 2-one ($,) via 1-(4-methylpheny1)-hexane-2.5-dione( 2 ) .1,4-Addition of methyl group into $, furnished 3,3-dimethyl-2-(4-methylpheny1)cyclopentanone (;I).This result constitutes a formal total synthesis of cuparene (XI.Since the first isolation of the sesouiterpene hydracarbon cuparene (4) by Enzell and ~rdtman', many related compounds with various oxidation patterns in the aromatic