gebhart/patrepeval huggingface dataset:
Characterization of the Leader Papain-like Proteinase of MHV-A59: Identification of a New in Vitro Cleavage Site (1995)

Sequence analysis of the mouse hepatitis virus, strain A59 (MHV-A59) genome predicts the presence of two papain-like proteinases encoded within the first open reading frame (ORF 1a) of the replicase gene. The more 5' of these domains, the leader papain-like proteinase, is responsible for the cleavage of the amino terminal protein, p28. The core of this proteinase domain was defined to between amino acids 1084 and 1316 from the beginning of ORF 1a. Through the use of deletion analysis coupled with in vitro expression, we studied the role of the coding region between p28 and the leader papain-like proteinase on the cleavage of p28 itself. Expression of a series of deletion mutants showed processing of p28, albeit at lower levels. Reduced p28 production resulting from a 0.4-kb deletion positioned between p28 and the proteinase domain suggests an involvement of this region in catalytic processing. Some mutants displayed cleavage patterns indicative of a second cleavage site. Interestingly, this new cleavage site identified in vitro maps to a position similar to the expected cleavage site of a p65 polypeptide detected in MHV-A59-infected cells. Mutagenesis of the catalytic His1272 residue demonstrates that both cleavages observed are mediated by the leader papain-like proteinase encoded in ORF 1a.
Eidothea open short test tool (2007)

Eidothea open short test tool is able to test all open short condition including single pin open short failure and multiple pin open short failure. Eidothea performs open short test on 112 lead QFP (quad flat package) within 1.12 seconds. Figure 10 shows the full coverage of open short test that is captured by Eidothea. Eidothea can cover IO to IO open short test, IO to VSS open short test, IO to VDD open short test, VSS to VSS open short test, VSS to VDD open short test and VDD to VDD open short test.
Preparation and Some Physical Properties of ZnGeP<sub>2</sub> (1969)

Abstract Single crystal ZnGeP 2 has been prepared by slow cooling from the melt and by vapour transport of the constituent elements in a phosphorus atmosphere. X‐ray powder studies lead to a c/a ratio for the chalcopyrite‐structured ZnGeP 2 of 1.961. Thermal analysis measurements give a phase change at (952 ± 2) °C, probably disordering of chalcopyrite to zinc blende, and congruent melting at 1025 °C. Resistance‐temperature investigations suggest that acceptor levels at 0.10 and 0.62 eV control the free carrier concentration above and below room temperature, respectively. Undoped ZnGeP 2 is always p‐type. Minority carrier studies point to an electron mobility between 10 3 and 10 4 cm 2 /Vs. Photoconductivity and optical absorption measurements lead to the conclusion that the direct energy gap in ZnGeP 2 is 2.25 eV.
Submucosal Diathermy of the Inferior Turbinate and the Congested Nose (1985)

Surgical correction of the congested nose is frequently attempted. In the absence of a septal deformity, engorgement of the inferior turbinate is usually held to be the culprit, and various procedures have been advocated to counter this problem. Submucosal diathermy to the inferior turbinates is widely practised, but relatively little has been published about it. 204 patients who underwent submucosal diathermy of the inferior turbinates between 1977 and 1983 have been studied. 60 patients have been followed up by questionnaire, for periods ranging from 1 to 5 years since surgery. Surgery was of benefit in up to 72% of cases. Surgical technique and the problems of patient selection and assessment are discussed.
Delayed transplantation of human neural precursor cells improves outcome from focal cerebral ischemia in aged rats (2010)

Neural precursor cell (NPC) transplantation may have a role in restoring brain function after stroke, but how aging might affect the brain's receptivity to such transplants is unknown. We reported previously that transplantation of human embryonic stem cell (hESC)-derived NPCs together with biomaterial (Matrigel) scaffolding into the brains of young adult Sprague-Dawley rats 3 weeks after distal middle cerebral artery occlusion (MCAO) reduced infarct volume and improved neurobehavioral performance. In this study, we compared the effect of NPC and Matrigel transplants in young adult (3-month-old) and aged (24-month-old) Fisher 344 rats from the National Institute on Aging's aged rodent colony. Distal MCAO was induced by electrocoagulation, and hESC-derived NPCs were transplanted into the infarct cavity 3 weeks later. Aged rats developed larger infarcts, but infarct volume and performance on the cylinder and elevated body swing tests, measured 6-8 weeks post-transplant, were improved by transplantation. We conclude that advanced age does not preclude a beneficial response to NPC transplantation following experimental stroke.
Orthokeratology. Part II: Evaluating the Tabb method. (1984)

This summary of the experimental design and methodology of a study evaluating ocular response to orthokeratology presents a method of orthokeratology that involves modifying the optic zone diameter, intermediate, and peripheral curve zones of a PMMA contact lens. An evaluation of the Tabb method of orthokeratology to determine the ocular tissue changes most responsible for observed refractive and acuity changes found that noncorneal parameters measured did not change, whereas two corneal parameters measured did change as orthokeratology occurred. The corneal parameters that appeared most involved in refractive and acuity changes were corneal thickness and shape factor. The Tabb method of orthokeratology did not cause an increase in corneal with-the-rule astigmatism.
1,4-Thiazans. I. C-Alkyl Thiomorpholines (1954)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXT1,4-Thiazans. I. C-Alkyl ThiomorpholinesBernard Idson and Paul E. SpoerriCite this: J. Am. Chem. Soc. 1954, 76, 11, 2902–2906Publication Date (Print):June 1, 1954Publication History Published online1 May 2002Published inissue 1 June 1954https://pubs.acs.org/doi/10.1021/ja01640a013https://doi.org/10.1021/ja01640a013research-articleACS PublicationsRequest reuse permissionsArticle Views164Altmetric-Citations8LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Engineered quasi-phase-matching for second-harmonic generation (2003)

An approach for analytically calculating the second-harmonic output field from an arbitrary quasi-phase-matched non-linear crystal is presented. By applying this method within a simulated annealing minimization routine we demonstrate a way of designing quasi-phase-matched gratings whose conversion response can be tailored to closely match any chosen profile. The influence on the final conversion response of important parameters such as the number of crystal domains and the algorithm temperature is presented in detail.
Human Trajectory Prediction using Spatially aware Deep Attention Models (2017)

Trajectory Prediction of dynamic objects is a widely studied topic in the field of artificial intelligence. Thanks to a large number of applications like predicting abnormal events, navigation system for the blind, etc. there have been many approaches to attempt learning patterns of motion directly from data using a wide variety of techniques ranging from hand-crafted features to sophisticated deep learning models for unsupervised feature learning. All these approaches have been limited by problems like inefficient features in the case of hand crafted features, large error propagation across the predicted trajectory and no information of static artefacts around the dynamic moving objects. We propose an end to end deep learning model to learn the motion patterns of humans using different navigational modes directly from data using the much popular sequence to sequence model coupled with a soft attention mechanism. We also propose a novel approach to model the static artefacts in a scene and using these to predict the dynamic trajectories. The proposed method, tested on trajectories of pedestrians, consistently outperforms previously proposed state of the art approaches on a variety of large scale data sets. We also show how our architecture can be naturally extended to handle multiple modes of movement (say pedestrians, skaters, bikers and buses) simultaneously.
A Dual Polarized Vivaldi Antenna with the Notched Band by Feed Line Filter on Conductive Plane (2018)

In this paper, a dual polarized Vivaldi antenna with the notched band by the feed line filter on conductive plane is presented. Two Vivaldi antennas are intercrossed vertically to realize dual polarization. Each Vivaldi antenna is placed on the substrate with the size of 62 × 50.5 mm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> . The thickness and relative permittivity of substrate are 0.6 mm and 2.65, respectively. In addition, the front-to-back ratio of the antenna is improved by adding the 160 mm diameter conductive plane below. The notched band is achieved by introducing printed capacitively loaded loop (CLL) resonators close to the feeding line as filter of the Vivaldi antenna. The simulated and measured results demonstrate that the antenna achieves an impedance bandwidth from 2.6 GHz to 14.9 GHz (VSWR ≤ 2) except the bandwidth of 6.0 ~ 7.5 GHz.
Green tea and cancer in humans: A review of the literature (1998)

Researchers have investigated green tea as a potential protectant against cancer. This review focuses on studies of green tea in humans. Green tea contains polyphenols, chemicals that act as powerful antioxidants. Epidemiological and human studies have shown varying results. Thirty-one human studies and four reviews were examined. Among five studies reporting on colon cancer, three found an inverse association and one reported a positive association. For rectal cancer, only one of four studies reported an inverse association; increased risks were seen in two of the studies. An inverse association is suggested for urinary bladder cancer in two of two studies. Of 10 studies examining the association of green tea and stomach cancer, 6 suggest an inverse and 3 a positive association. The most comprehensive of these studies supports an inverse association of green tea and stomach cancer. Pancreatic cancer studies hint at an inverse association in two of three studies. A strong inverse effect was found with green tea and esophageal cancer. Lung cancer studies have shown an inverse effect with Okinawan tea, yet tentatively increased risk was shown in another study. Although human studies have their limitations, the research has warranted a further look into the effects of green tea and cancer.
Respiratory symptoms and lung function in hemp workers. (1990)

Respiratory symptoms and abnormalities of lung function were studied in 84 female and 27 male hemp workers employed in two textile mills (A and B) processing soft hemp (C sativa). In mill A 46 women and 27 men were investigated and 38 female workers were studied in mill B. Forty nine women and 30 men from a non-dusty industry served as controls. A significantly higher prevalence of almost all chronic respiratory symptoms was found in female hemp workers when compared to control workers. Among the men these differences were significant for nasal catarrh and sinusitis. A high prevalence of byssinosis was found among female hemp workers in both mills (group A, 47.8%; group B, 57.9%) as well as in the male workers (66.7%). Statistically significant across shift reductions in lung function were found for all ventilatory capacity measurements in female and male hemp workers varying from 7.1% for forced expiratory volume in one second (FEV1) to 15.1% for flow rates at 50% vital capacity (FEF50). Measured Monday baseline values before the work shift were significantly lower than expected for hemp workers, being particularly reduced for FEF25 and FEF50. The data suggest that occupational exposure to hemp dust is a significant risk factor for the development of acute and chronic lung disease in workers employed in this textile industry.
Exploring data rate limitations of channel front-ends for rigid disk drives (2001)

Each of the components of the channel front-end (i.e., medium, heads, interconnects, and read/write electronics), can limit the data rate. In the read path, the head-to-electronics suspension interconnect forms the major bottleneck. The skin-effect losses, multi-mode propagation effects and reflections limit the maximum achievable data rate. In the write path, the reflections along the suspension interconnect causing long settling times and also the relatively slow response of the ferromagnetics of the write-head limit the data rate. Modeling shows that the overall write path is data rate limited by settling times that are too long, leading to uncorrectable timing distortion in the location of the one but nearest neighbor transitions.
Fuzzy logic based vision enhancement using sigmoid function (2017)

In this paper, the image haze-removal technique proposed by us is free from artifacts as well as it's execution time is also very less. The method proposed here can overcome the halo-artifacts occurring due to non-uniform transmission within patches by patch size regulation and is also capable of removing the blocking artifacts (especially in the sky region) and can restore the contrast of the image by using sigmoid function and fuzzy logic. Moreover, since we have taken a large number of hazy images in our database and have obtained satisfactory results by applying the algorithm on all the hazy images, hence we can state that our algorithm is not dependent on the features of the hazy images and can remove haze from all kinds of hazy images irrespective of its characteristics.
Novel role of zinc in the regulation of prostate citrate metabolism and its implications in prostate cancer (1998)

The prostate gland of humans and many other animals has the major function of accumulating and secreting extraordinarily high levels of citrate. This specialized metabolic process of "net citrate production" is the result of unique metabolic capabilities of the secretory epithelial cells. Most importantly, in prostate cancer (Pca) the capability for net citrate production is lost. In addition to citrate, the normal and BPH (benign prostatic hyperplasia) prostate also accumulates the highest levels of zinc in the body. As with citrate, in Pca the ability for high zinc accumulation is diminished. These and other correlations between zinc and citrate in the prostate have been indicative of an important role of zinc in the regulation of citrate metabolism in normal and malignant prostate epithelial cells. The link between zinc and citrate metabolism has now been established. The intramitochondrial accumulation of high zinc levels inhibits mitochondrial (m-) aconitase activity, which inhibits citrate oxidation. This essentially truncates the Krebs cycle and markedly decreases the cellular energy (ATP) production normally coupled to citrate oxidation. It is also clear that zinc accumulation in citrate-producing prostate epithelial cells is regulated by testosterone and by prolactin. These relationships form the basis for a new concept of the role of zinc and citrate-related energy metabolism in prostate malignancy. The inability of malignant prostate cells to accumulate high zinc levels results in increased citrate oxidation and the coupled ATP production essential for the progression of malignancy. The concept offers new approaches to the treatment of Pca.
’Looking Through a Soda Straw’: Mediated Vision in Remote Warfare (2017)

Image-guided military operations embed soldiers into a complex system of image production, transmission, and perception. These soldiers separate their bodies from the battlefield, but they also mediate between them. In particular, remote controlled operations of so-called unmanned aerial systems (UAS) require the synchronization between human actors and technical sensors in real-time, such as the knowledge of a situation. This situational awareness relies almost exclusively on the visualization of sensory data. This human-machine entanglement corresponds to a new operative modality of images which differs from previous forms of real-time imaging such as live broadcasting, as it is based on a feedback-loop that turns the observer into an actor. Images are not simply analyzed and interpreted but become agents in a socio- technological assemblage. The paper will draw upon this functional shift of images from a medium of visualization towards a medium that guides operative processes. Based on the analysis of vision, architecture, and navigation in remote warfare, it will discuss how real-time video technology and the mobilization of sensor and transmission technology produce a type of intervention, in which action and perception is increasingly organized and determined by machines.
Parallel 4×4 2D transform and inverse transform architecture for MPEG-4 AVC/H.264 (2003)

Transform coding has been widely used in video coding standards. In this paper, a hardware architecture for accelerating transform coding operations in MPEG-4 AVC/H.264 is presented. This architecture calculates 4 inputs in parallel by fast algorithms described previously. The transpose operations are implemented by a register array with directional transfers. This architecture has been mapped into a 4 /spl times/ 4 multiple transforms unit and synthesized in TSMC 0.35um technology. The multiple transform processor can process 320M pixels/sec at 80Mhz for all 4 /spl times/ 4 transforms used in MPEG-4 AVC/ H.264.
Expression of the Na+/I- Symporter Gene in Human Thyroid Tumors: A Comparison Study with Other Thyroid-Specific Genes (1999)

The expression of 4 thyroid tissue-specific genes [Na(+)/I(-) symporter (NIS), thyroid peroxidase (TPO), thyroglobulin (Tg), TSH receptor (TSH-R)] as well as of the glucose transporter type 1 (Glut1) gene was analyzed in 90 human thyroid tissues. Messenger ribonucleic acids were extracted from 43 thyroid carcinomas (38 papillary and 5 follicular), 24 cold adenomas, 5 Graves' thyroid tissues, 8 toxic adenomas, and 5 hyperplastic thyroid tissues; 5 normal thyroid tissues were used as reference. A kinetic quantitative PCR method, based on the fluorescent TaqMan methodology and real-time measurement of fluorescence, was used. NIS expression was decreased in 40 of 43 thyroid carcinomas (10- to 1200-fold) and in 20 of 24 cold adenomas (2- to 700-fold); it was increased in toxic adenomas and Graves' thyroid tissues (up to 140-fold). TPO expression was decreased in thyroid carcinomas, but was normal in cold adenomas; it was increased in toxic adenomas and Graves' thyroid tissues. Tg expression was decreased in thyroid carcinomas, but was normal in the other tissues. TSH-R expression was normal in most tissues studied and was decreased in only some thyroid carcinomas. In thyroid cancer tissues, a positive relationship was found between the individual levels of expression of NIS, TPO, Tg and TSH-R. No relationship was found with the age of the patient. Higher tumor stages (stages >I vs stage I) were associated with lower expression of NIS (P = 0.03) and TPO (P < 0.01). Expression of the Glut1 gene was increased in 1 of 24 adenomas and in 8 of 43 thyroid carcinomas. In 6 thyroid carcinoma patients, (131)I uptake was studied in vivo; NIS expression was low in all samples; 3 patients with normal Glut-1 gene expression had (131)I uptake in metastases, whereas the other 3 patients with increased Glut-1 gene expression had no detectable 131I uptake. In conclusion, this study shows 1) a reduced expression of NIS gene in most hypofunctioning benign and malignant thyroid tumors; 2) a differential regulation of the expression of thyroid-specific genes; 3) an increased expression of Glut-1 gene in some malignant tumors that may suggest a role for glucose derivative tracers to detect in vivo thyroid cancer metastases by positron emission tomography scanning.
Pyridone, V Oxidativer Abbau der N‐Methylnicotone (1976)

Abstract Der Abbau von „N‐Methylnicoton”︁ nach Karrer mit Phosphorpentachlorid und anschließender Permanganatoxidation führt entgegen den ursprünglichen Angaben nicht zu 2‐ sondern zu 6‐ Chlornicotinsäure. Der Chromsäureabbau von 1‐Methyl‐3‐[1‐methylpyrrolidyl‐(2)]‐pyridon‐(2) und ‐pyridon‐(6) ergibt in beiden fällen die Hygrinsäure. Bei Einsatz von optisch aktivem Material wird im Gesamtreaktionsverlauf keine Racemisierung beobachtet.
A taxa de crecemento compatible co equilibrio externo: un test para a economía española (2006)

In this paper a Balance of Payments Constrained Growth Model is tested. Usually theses models specify a relationship among income, imports and the rest-of-the world income, while here the specified relationship is among income, domestic demand and the rest-of-the world income. Once the relationship is regressed, the balance of payments equilibrium growth rate is obtained. We test whether the sustainable equilibrium growth rate obtained in such a way predicts accurately the actual rate of growth. Finally, we determine which components of domes- tic demand are more relevant in order to determine economic growth. The results show that, for the Spanish Economy, the rate of economic growth is predicted quite precisely as a function of private demand and the rest-of-the world income. Keywords: External equilibrium / Economic growth.
The Options Course: High Profit & Low Stress Trading Methods (1998)

Introduction to Options Trading. The Big Picture. Elements of a Good Investment. A Short Course in Investment Economics. How to Spot Explosive Opportunities. Option Basics. Introduction to Delta Neutral Trading. The Greeks and Option Pricing. Risk Profiles. Risk and Margin. Basic Trading Strategies. The Nuts and Bolts of Delta Neutral Trading. Advanced Delta Neutral Strategies. Trading Techniques for Range-Bound Markets. Increasing Your Profits with Adjustments. Processing Your Trade. Placing Orders. Final Summary. Appendices. Glossary. Index. George Fontanills' Trading Package.
Creep Properties of lnconel-617 in Air and Helium at 800 to 1000°C (1984)

Creep and structural data are presented on three casts of Inconel alloy 617 tested in air and controlled impurity helium for times up to 42 000 h in a test facility at CIIR, Oslo. Prior cold work reduced initial creep rate at 850°C, but it also reduced the room-temperature tensile ductility measured after samples had been subjected to small creep strains.The main effect of environment was that air promoted high rupture ductilities, relative to the helium atmosphere used in this work. It was found that air testing caused nucleation and growth of many oxidefilled cracks. Carburization occurred during the helium tests, but this had little influence on rupture life (relative to air tests) under the experimental conditions used here.Structural examination showed that creep conditions favored the precipitation of carbides on grain boundaries transverse to the imposed tensile stress.