gebhart/patrepeval huggingface dataset:
2712 Fundamental analysis on the dynamic behavior of buttress threads (2005)

This paper describes a fundamental analysis on dynamic rotational slip between male and female buttress threads with static load-carrying and non-slip characteristics, which occurs when the flank faces of a pair of threads contact each other with relative axial speed. The mixed lubrication theory is employed to calculate friction coefficient between contact surfaces, which determines the dynamic behavior of threads, and calculation results are evaluated by comparison with experimental results. The analysis shows the calculation method proposed in this paper can be used to estimate the actual amount of slip.
Evaluation of the Precision and Accuracy of a Uranium Isotopic Analysis Using Glow Discharge Optogalvanic Spectroscopy (1995)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTEvaluation of the Precision and Accuracy of a Uranium Isotopic Analysis Using Glow Discharge Optogalvanic SpectroscopyC. M. Barshick, R. W. Shaw, J. P. Young, and J. M. RamseyCite this: Anal. Chem. 1995, 67, 20, 3814–3818Publication Date (Print):October 1, 1995Publication History Published online1 May 2002Published inissue 1 October 1995https://pubs.acs.org/doi/10.1021/ac00116a033https://doi.org/10.1021/ac00116a033research-articleACS PublicationsRequest reuse permissionsArticle Views124Altmetric-Citations24LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Proximity Effect and Magnetic Field Calculation in GIL and in Isolated Phase Bus Ducts (2001)

This paper deals with an integral numerical method suitable to predict the current density distribution in typical multiconductor systems represented by gas-insulated lines (GIL) or by isolated phase MV bus ducts, highlighting their proximity effect. Besides the prediction of power density distribution due to Joule losses, the integral approach makes the evaluation of the external flux density easy. The simplicity of the approach, the conciseness of the matrix algebra applied, and the close-to-reality procedure make this method extremely attractive for self-made software implementation on any commercially available math packages such as Matlab. For the sake of comparison, a finite-element method (FEM) model of the system has been implemented. In this model, a coupling between electric circuit and electromagnetic model has been used in order to take into account the real power supply conditions.
Franco-Irish military connections, 1590–1945. Edited by Nathalie Genet-Rouffiac and David Murphy. Pp 304. Dublin: Four Courts Press. 2009. €55. (2010)

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ChemInform Abstract: MIT COENZYMEN UND BASENPAAREN VERWANDTE SYNTHETISCHE SPEKTROSKOPISCHE MODELLE 10. MITT. QUATERNISIERTE BISNICOTINAMIDE (1972)

Abstract Die intramolekularen Wechselwirkungen der quaternisierten Nicotinamidgruppen in Verbindungen des Typs (I) werden anhand der hyperchromen intramolekularen Störung von UV‐Banden der quaternisierten Nicotinamidgruppe durch Vergleich mit den Oszillatorstärken von 3‐Carbamoyl‐1‐propyl‐pyridiniumchlorid ermittelt.
The Association of Lacking Insurance With Outcomes of Severe Sepsis (2013)

Uninsured are more likely to die following admission for severe sepsis than patients with insurance, even after adjusting for potential confounders. This was not due to a hospital effect or demographic or clinical factors available in our administrative database. Further research should examine the mechanisms that lead to this association.
81. Absorption spectra of ketones. Part VII. The n→π* band of axial and equatorial 2-arylcyclohexanones (1962)

R. C. Cookson and J. Hudec, J. Chem. Soc., 1962, 429 DOI: 10.1039/JR9620000429
Phase II Study of Alemtuzumab Treatment in Patients with Pretreated T-Cell Lymphoma. (2004)

Abstract To evaluate the efficacy and toxcity of Alemtuzumab, an anti-CD52 monoclonal antibody in patients with relapsed or refractory cutaneous T-cell lymphomas and peripheral T-cell lymphomas. Between 2003 and March 2004, 10 previously treated patients with mycosis fungoides (MF; n=4) and peripheral T-cell lymphoma unspecified (PTCLU) with nodal involvement (n=6) were enrolled onto a phase II trial and treated with Alemtuzumab in our Institute. This monoclonal antibody was given at a dose of 10 mg 3 times a week for 4 consecutive weeks. Of the 10 patients, 2 (20%) achieved complete response (CR), 4 (40%) partial response (PR), and the remaining 4 showed no benefits from the treatment. In the MF subset were observed only PR (3/4, 75%), while in the PTCLU patients there were 2 (33%) CR and 1 (17%) PR, respectively. The durations of CRs were 3 and 8 months. Treatment was well tolerated; hematolgic toxicity was mild. In terms of infectious adverse events, cytomegalovirus reactivation occurred in 1 (10%) patient and none patient had additional suspect or manifest infection. The results of the present phase II study show activity of Alemtuzumab as a single agent in patients with pretreated CTCL and PTCL using a low dose schedule; at the same time, this efficacious reduced dose permitts to avoid treatment-related mortality and to curtail the CMV reactivation rate.
Characterization of the Biosynthesis, Processing and Kinetic Mechanism of Action of the Enzyme Deficient in Mucopolysaccharidosis IIIC (2011)

Heparin acetyl-CoA:alpha-glucosaminide N-acetyltransferase (N-acetyltransferase, EC 2.3.1.78) is an integral lysosomal membrane protein containing 11 transmembrane domains, encoded by the HGSNAT gene. Deficiencies of N-acetyltransferase lead to mucopolysaccharidosis IIIC. We demonstrate that contrary to a previous report, the N-acetyltransferase signal peptide is co-translationally cleaved and that this event is required for its intracellular transport to the lysosome. While we confirm that the N-acetyltransferase precursor polypeptide is processed in the lysosome into a small amino-terminal alpha- and a larger ß- chain, we further characterize this event by identifying the mature amino-terminus of each chain. We also demonstrate this processing step(s) is not, as previously reported, needed to produce a functional transferase, i.e., the precursor is active. We next optimize the biochemical assay procedure so that it remains linear as N-acetyltransferase is purified or protein-extracts containing N-acetyltransferase are diluted, by the inclusion of negatively charged lipids. We then use this assay to demonstrate that the purified single N-acetyltransferase protein is both necessary and sufficient to express transferase activity, and that N-acetyltransferase functions as a monomer. Finally, the kinetic mechanism of action of purified N-acetyltransferase was evaluated and found to be a random sequential mechanism involving the formation of a ternary complex with its two substrates; i.e., N-acetyltransferase does not operate through a ping-pong mechanism as previously reported. We confirm this conclusion by demonstrating experimentally that no acetylated enzyme intermediate is formed during the reaction.
Note on Virtual Phonon Processes in Thermal Accommodation (1969)

It is shown that the effect of the inclusion of virtual phonon processes accompanying a real single-phonon emission or absorption in calculating the accommodation coefficient for noble-gas atoms impinging on a metal surface is negligible. This result contradicts the conclusion of a recently published calculation.
Effects of Duration of Exposure to Low Temperatures on Bolting and Flowering of Rosetted Seedlings and Lateral Bud Emergence after Flower Harvest in Elatum Hybrids of Delphinium. (2002)

エラータム系デルフィニウムのロゼット打破に必要な低温遭遇量を知るため, 最初に, 無加温で栽培した苗を順次加温することにより, 秋∿冬季の自然低温遭遇によってロゼットが打破される時期を調べた.次いで, 2番花および3番花となるシュート基部の側芽についても, 同様の方法でその伸長に必要な低温遭遇量を検討した.秋∿冬季にロゼット化した'ブルースプリングス'の苗は, 自然日長下で, 12月15日まで自然低温に遭遇させるとほぼロゼットが打破された.ロゼットが打破されるために必要な低温遭遇期間は, 最低夜温が7℃程度の自然低温で30日間であったが, 加温後の長日処理は必要な低温遭遇期間を10日間程度短縮させた.2番花となる1番花のシュート基部の側芽は, 1番花の採花直後には休眠あるいはロゼット化しており, 最低夜温5℃程度の自然低温に30日間遭遇させると, ほぼ確実に伸長させることができた.伸長した1番花のシュート基部の側芽は, 最低夜温を10℃に加温すると, 加温開始から70∿74日後に株当たり平均2.1本が開花した.3番花となる2番花のシュート基部の側芽は, 2番花が4月上旬に開花した後, ロゼット化することなく抽だいし, 約2か月後に開花した.
Anti-bacterial effect of marine sea grasses mediated endophytic actinomycetes against K. pneumoniae (2021)

In this study, the pure, pale white, powdery nature and pigment produced endophytic actinomycetes strains were isolated from marine Sea grasses sample. The isolated strains were endophytes as confirmed by surface sterilization and validation methods. The anti-bacterial efficacy materials of the crude compound were extracted by liquid–liquid extraction using various organic solvents. Anti-bacterial efficacy of the isolated actinomycetes strain RMN 10 was exhibited excellent anti-bacterial activity against K. pneumoniae at increasing concentration. In addition, the minimum inhibition concentration (MIC) of the crude actinomycetes compound has excellent anti-bacterial activity at 250 µg/mL concentration and this concentration was fixed as a MIC. Further, the structural and shape damages of actinomycetes crude compound treated K. pneumoniae cells were clearly identified in SEM images. All the invitro experiments were proved that the actinomycetes compound has excellent anti-bacterial activity against K. pneumoniae.
Reduction of Colitis by Prebiotics in HLA-B27 Transgenic Rats Is Associated with Microflora Changes and Immunomodulation (2005)

HLA-B27 transgenic rats develop spontaneous colitis under specific pathogen-free conditions (SPF) but germ-free rats remain disease-free, emphasizing a role for intestinal bacteria in the pathogenesis of chronic intestinal inflammation. Prebiotics are dietary substances that affect the host by stimulating growth and/or activity of potentially health promoting bacteria. The aims of this study were to investigate whether prebiotics can prevent colitis in SPF HLA-B27 rats, and secondly, to explore mechanisms of protection. SPF HLA-B27 transgenic rats received orally the prebiotic combination long-chain inulin and oligofructose (Synergy 1), or not, prior to the development of clinically detectable colitis. After seven weeks, cecal and colonic tissues were collected for gross cecal scores (GCS), histologic inflammatory scores (scale 0-4), and mucosal cytokine measurement. Cecal and colonic contents were collected for analysis of the gut microbiota by PCR-denaturing gradient gel electrophoresis (PCR-DGGE) and fluorescent in-situ hybridization (FISH), and analysis of short-chain fatty acid composition. Prebiotic treatment significantly decreased GCS and inflammatory histologic scores in the cecum and colon. Prebiotic treatment also decreased cecal IL-1beta, but increased cecal TGF-beta concentrations. Inulin/oligofructose altered the cecal and colonic PCR-DGGE profiles, and FISH analysis showed significant increases in cecal Lactobacillus and Bifidobacterium populations after prebiotic treatment compared with water-treated rats. In conclusion, the prebiotic combination Synergy 1 reduced colitis in HLA-B27 transgenic rats, which effect was associated with alterations to the gut microbiota, decreased tissue proinflammatory cytokines and increased immunomodulatory molecules. These results show promise for prebiotics as primary or adjuvant maintenance therapy for chronic inflammatory bowel diseases.
Analiza površine vlaken z mikroskopijo atomskih sil (AFM) (2000)

Mikroskopija atomskih sil (ang.: atomic force microscopy AFM) je ena od oblik mikroskopij, ki omogoca opazovanje neprevodnih povrsin v nanometrskem merilu. Razvila sta jo Nobelova nagrajenca s podrocja fizike, Binnig in Roher [5, 6]. Od izuma leta 1986 pa do danes je mikroskop atomskih sil postal zelo pomemben instrument v laboratorijih za fiziko trdnih snovi, kemijskih, polimernih in bioloskih laboratorijih, pojavlja pa se tudi že v industriji. Izredno uporaben je na podrocju tekstilstva, ceprav njegovih zmožnosti na tem podrocju do sedaj se niso intenzivneje raziskali.
Struktura vlaken je zapletena. Vecinoma je morfologija povrsine drugacna od tiste v notranjosti. Oblika povrsine vlaken vpliva na procese, ki se odvijajo na mejnih povrsinah. Zato je toliko bolj pomembno uvajanje novih metod na podrocje analize povrsinskih lastnosti vlaken. Mikroskop atomskih sil AFM nudi informacije o fibrilni strukturi vlaken, poleg tridimenzionalne analize povrsine vlaken omogoca tudi merjenje medmolekulskih in medatomskih sil velikostnega reda nekaj nN. V primerjavi z elektronskim mikroskopom je priprava vzorca mnogo enostavnejsa. V prispevku je opisan princip delovanja AFM in predstavljeni rezultati analize PAG filamenta. Na povrsini PA6 monofilamenta je vidna fibrilna struktura. Najmanjsi fibrili, ki jih je mogoce razlociti, imajo premer le nekaj 10 nm. Združujejo se v vecje fibrilne snope, ki v najsirsih predelih merijo 1 do 2 μm. Praznine in vdolbine na povrsini so razlicno velike (30-200 nm) in so okrogle ali ovalne oblike, usmerjene v smeri osi vlakna. Povrsina filamenta je v smeri osi vlakna manj razbrazdana; visinska razlika med najnižjimi in najvisjimi podrocji znasa v precni smeri do 70 nm, v vzdolžni smeri pa do 30 nm.
Correlation between preirradiation channel mobility and radiation-induced interface-trap charge in metal-oxide-semiconductor transistors (1991)

We find a strong correlation between preirradiation channel resistance and radiation-induced interface-trap charge in n-channel metal-oxide-semiconductor (MOS) transistors. While it has long been known that the postirradiation mobility of MOS transistors degrades with exposure to ionizing radiation, we believe this is the first time that differences in the postirradiation interface-trap charge have been linked to differences in preirradiation device parameters. A simple model is presented that relates the observed variations in preirradiation channel resistance to scattering from defects at the Si/SiO2 interface which may be precursors to the radiation-induced interface-trap charge.
The <scp>S</scp>taufen<scp>1</scp>‐dependent cell cycle regulon or how a misregulated <scp>RNA‐</scp>binding protein leads to cancer (2021)

In recent years, an increasing number of reports have linked the RNA-binding protein Staufen1 (STAU1) to the control of cell decision making. In non-transformed cells, STAU1 balances the expression of messenger RNA (mRNA) regulons that regulate differentiation and well-ordered cell division. Misregulation of STAU1 expression and/or functions changes the fragile balance in the expression of pro- and anti-proliferative and apoptotic genes and favours a novel equilibrium that supports cell proliferation and cancer development. The misregulation of STAU1 functions causes multiple coordinated modest effects in the post-transcriptional regulation of many RNA targets that code for cell cycle regulators, leading to dramatic consequences at the cellular level. The new tumorigenic equilibrium in STAU1-mediated gene regulation observed in cancer cells can be further altered by a slight increase in STAU1 expression that favours expression of pro-apoptotic genes and cell death. The STAU1-dependent cell cycle regulon is a good model to study how abnormal expression of an RNA-binding protein promotes cell growth and provides an advantageous selection of malignant cells in the first step of cancer development.
Redes temáticas en la web: una propuesta de componentes y caracterización (2014)

Many types of research on Social Sciences, Political Sciences and Market Sciences present the need to obtain information about the opinion or public reaction to certain topics. The Web is a source of information which might help satisfying this need, but to achieve this goal it is necessary to develop concepts and methodologies allowing to understand how it works, and to extract the different forms of knowledge it contains. This article presents the concept of “issue network”, and through a theoretical revision of hyperlink studies, the concepts of “issue” and “actor” and the concept of issue network itself, we expose its characteristics, the problems it solves and the possibilities it offers to opinion studies.
Parametric point spread function modeling and reduction of stray light effects in digital still cameras (2007)

In any real optical imaging system, some portion of the entering light flux is misdirected to undesired locations due to scattering from surface imperfections and multiple reflections between optical elements. This unwanted light is called stray light. Its effects include lower contrast, reduced detail, and color inaccuracy. Accurate removal of stray-flux effects first requires determination of the stray light point-spread function (PSF) of the system. For digital still cameras, we assume a parametric, shift-variant, rotationally invariant PSF model. For collection of data to estimate the parameters of this model, we use a light source box that provides nearly uniform illumination behind a circular aperture. Several images of this light source are captured when it is at different locations in the field of view of the camera. Also, another exposure of each scene with a different shutter speed is used to provide details in the darker regions. A subset of the data obtained from these images is used in a nonlinear optimization algorithm. After estimating the parameters of the PSF model, we provide the results of applying the correction algorithm to the images taken of real world scenes.
Identification and purification of the specific antigen of<i>Paracoccidioides brasiliensis</i>responsible for immunoelectrophoretic band E (1977)

A new purified antigen (E2) of Paracoccidioides brasiliensis mycelial growth phase was isolated by immunoadsorption from a crude metabolic soluble extract of the fungus. The antiserum prepared in a rabbit by inoculation of E2 antigen developed only one immunodiffusion line with the crude metabolic extract. Findings on immunological analysis showed that E2 antigen is the antigenic component of immunoelectrophoretic band E. The isolated antigens did not possess detectable alkaline phosphatase activity. It reacted in immunodiffusion tests with all the sera (14/14) from P. brasiliensis infected patients containing precipitating antibodies.
Ensuring query integrity for spatial data in the cloud (2012)

With the popularity of location-based services (LBS) and the abundant usage of smart phones, tablets and other GPS-enabled devices, the necessity of providing efficient, reliable and cost-effective spatial data services has grown rapidly over the past few years. Consequently, outsourcing databases to third party service providers is becoming a common practice for data owners to reduce the cost of managing and maintaining databases in-house but maintaining the same quality-of-service to their clients. Meanwhile, the fast arising trend of Cloud storage and Cloud computing services has provided a flexible and cost-effective platform for hosting data from businesses and individuals, further enabling many location-based applications. Nevertheless, in this new database outsourcing paradigm, how to ensure the integrity of the query results for the clients remains a challenging problem. 
To address the query integrity problem, we propose a new framework, named VN-Auth, which allows a client to verify the correctness and completeness of the result set retrieved from the Cloud using spatial neighborhood information derived from the Voronoi diagram of the underlying dataset. VN-Auth handles not only fundamental spatial query types, such as k-nearest-neighbor and range queries, but also more advanced query types like reverse k nearest neighbors, k aggregate nearest neighbors, and spatial skylines. Furthermore, we show that VN-Auth can be extended from the Euclidean space to road networks where objects can only move on pre-defined trajectories, enabling spatial network query integrity. We evaluated VN-Auth based on real-world datasets using mobile devices (Google Droid smart phones with Android OS) as query clients. Compared to the current state-of-the-art approaches (i.e., methods based on Merkle hash trees), our experiments show that VN-Auth produces significantly smaller verification objects and is more computationally efficient, especially for queries with low selectivity.
Is There Merit in Merit Aid? (2017)

Interview with Dr. Roy Ziegelstein on the increasing concentration of medical-school debt among fewer students. (08:47)Download There is broad agreement that something must be done to address medical students’ increasing educational debt. An important question is whether merit scholarships are part of the solution or part of the problem.
Comparison of Luteinizing Hormone and Progesterone in Blood and Metabolites of Progesterone in Urine of Domestic Sows during the Estrous Cycle and Early Pregnancy (1970)

Yearling Hampshire sows, 15 pregnant and 8 nonbred, were used to compare hormone relationships during the estrous cycle and the first 26 to 28 days of pregnancy. Blood and urine were collected on day 16 preceding and during the third post-weaning estrus. Subsequent collections were made from 12 of the sows on day 2 and the remainder on day 4, and at 4 day intervals thereafter through days 26 or 28. Urine was analyzed for 4 metabolites of progesterone using enzyme and solvolysis procedures for hydrolysis during extraction, and gas-liquid chromatography for quantification of the compounds as the acetate derivatives. Luteinizing hormone (LH) was determined by radioimmunoassay. Progesterone concentration in peripheral blood plasma was similar, except at periods around estrus, whether determined by double isotope derivative or competitive protein binding assays (n=86; r=0.75; P<.01). Days when samples were collected in relation to estrus or breeding were significantly related to the substances measured. The data for pregnant sows differed significantly as compared to nonpregnant sows in levels of progesterone and LH in peripheral blood plasma and rate of excretion of two metabolites of progesterone in urine, namely 5β-pregnan-3α-ol-20-one and 5β-pregnan-3α,6α-diol-20-one. Compared to nonpregnant sows, changes in excretion of metabolites may be detected as early as the fourth to eighth day after breeding as indicated by increased excretion of 5β-pregnan-3α-ol-20-one and 5β-pregnan-3α,6α-diol-20-one. The four metabolites of progesterone were correlated with each other and with total metabolites at different stages of the estrous cycle and the first 28 days of pregnancy. It appears that measurement of 5β-pregnan-3α-ol-20-one in urine would provide reasonable estimates of luteal function and total metabolites of progesterone in urine.