gebhart/patrepeval huggingface dataset:
Excess loss caused by an outer layer in multimode step-index fibers: experiment (1977)

Experiments have been performed to evaluate the increase in loss due to an outer layer around the cladding in a multimode step-index fiber composed of core and cladding. Liquid has been used to simulate the outer layer. Measured excess loss for each mode group is in agreement with our previously developed electromagnetic theory. Total excess loss for all guided modes existing in the fiber has also been measured by varying the mode power distribution, the refractive index of the outer layer, the cladding thickness, and the wavelength. Results are found to be in good agreement with the theory, and it is concluded that the theory is correct.
Thermophysical property modeling of a hydrogenic pellet production system (2010)

J.W. Leachman, J.M. Pfotenhauer, and G.F. Nellis, Thermophysical property modeling of a hydrogenic pellet production system,� Transactions of the Cryogenic Engineering Conference, CEC: Advances in Cryogenic Engineering, 1218, (2010), 1570-1577.
Adherence, accumulation, and cell division of a natural adherent bacterial population (1996)

Developing dental bacterial plaques formed in vivo on enamel surfaces were examined in specimens from 18 adult volunteers during the first day of plaque formation. An intraoral model placing enamel pieces onto teeth was used to study bacterial plaque populations developing naturally to various cell densities per square millimeter of surface area of the enamel (W. F. Liljemark, C. G. Bloomquist, C. L. Bandt, B. L. Philstrom, J. E. Hinrichs, and L. F. Wolff, Oral Microbiol. Immunol. 8:5-15, 1993). Radiolabeled nucleoside incorporation was used to measure DNA synthesis concurrent with the taking of standard viable cell counts of the plaque samples. Results showed that in vivo plaque formation began with the rapid adherence of bacteria until ca. 12 to 32% of the enamel's salivary pellicle was saturated (ca. 2.5 x 10(5) to 6.3 x 10(5) cells per mm2). The pioneer adherent species were predominantly those of the "sanguis streptococci." At the above-noted density, the bacteria present on the salivary pellicle incorporated low levels of radiolabeled nucleoside per viable cell. As bacterial numbers reached densities between 8.0 x 10(5) and 2.0 x 10(6) cells per mm2, there was a small increase in the incorporation of radiolabeled nucleosides per cell. At 2.5 x 10(6) to 4.0 x 10(6) cells per mm2 of enamel surface, there was a marked increase in the incorporation of radiolabeled nucleosides per cell which appeared to be cell-density dependent. The predominant species group in developing dental plaque films during density-dependent growth was the sanguis streptococci; however, most other species present showed similar patterns of increased DNA synthesis as the density noted above approached 2.5 x 10(6) to 4.0 x 10(6) cells per mm2.
North Sea Chalk Porosity Resolved by Integration of Seismic Reflectivity and Well Log Data (2000)

B-30 NORTH SEA CHALK POROSITY RESOLVED BY INTEGRATION OF SEISMIC REFLECTIVITY AND WELL LOG DATA Abstract A regional study of the Upper Cretaceous – Danian chalk in the Central North Sea based on 2D seismic- and log- data revealed that: • Simplified carbonate porosity units can be resolved in the wells based on gamma ray and sonic logs (GR/DT-logs). • It is possible qualitatively to define areas of porous and tight chalk based on seismic reflectivity. In order to achieve the integration of the seismic and log data to elucidate the reservoir geology of the chalk a simple log-derived GR/DT-lithology
Impact of Color Blindness on Recognition of Blood in Body Fluids (2001)

Color blindness impairs recognition of blood in body fluids. Color-blind individuals and their health care providers need to be made aware of this limitation.
Alternative transcription cycle for bacterial RNA polymerase (2019)

Summary RNA polymerases (RNAPs) transcribe genes through a cycle of recruitment to promoter DNA, initiation, elongation, and termination. After termination, RNAP is thought to initiate the next round of transcription by detaching from DNA and rebinding a new promoter. We used single-molecule fluorescence microscopy to observe individual RNAP molecules after transcript release at a terminator. Following termination, RNAP almost always remained bound to DNA and sometimes exhibited one-dimensional sliding over thousands of basepairs. Unexpectedly, the DNA-bound RNAP often restarted transcription, usually in reverse direction, thus producing an antisense transcript. Furthermore, we report evidence of this “secondary initiation” in live cells, using genome-wide RNA sequencing. These findings reveal an alternative transcription cycle that allows RNAP to reinitiate without dissociating from DNA, which is likely to have important implications for gene regulation.
Predictors of radiologic progression free survival (rPFS) during abiraterone acetate (AA) treatment in a randomized phase II study of AA maintenance in combination with docetaxel (D) after disease progression to AA in metastatic castration resistant prostate cancer (mCRPC): ABIDO-SOGUG trial. (2017)

e16536 Background: AA improves OS and rPFS in asymptomatic/minimally symptomatic mCRPC patients. D is currently one of the standard treatments after progression to AA. However, the value of maintaining AA along with D despite progression to AA has not been tested. ABIDO trial aims to evaluate efficacy and safety of AA + D maintenance after disease progression to first line AA in mCRPC. Clinicopathologic features associated with rPFS during first line AA are presented. Methods: ABIDO trial is a randomized, phase II, open-label study with two stages. In stage I pts receive AA (1000 mg + prednisone (P) 10 mg qd) until progressive disease. In the stage II pts will be randomized to receive three-weekly D 75 mg/m 2 plus P 10 mg/d with (arm A) or without (arm B) AA 1000 mg/d. Pts had no visceral metastases, ECOG PS 0-1, and adequate organ functions. Clinicopathological predictors for rPFS to first line AA were estimated using the Kaplan-Meier method and independent associations were evaluated using Cox regression models. Results: 143 pts were included. Analyzed variables were: median age was 70y, 60% of pts had ECOG 0, 84% bone metastases (18% > 4), 42% BPI score 2-3, 53% Gleason > = 8, 30% PSA > 80 ng/mL, 38% node involvement and 11% had at least one lymph node > = 3 cm; 53% of pts achieved 4 weeks PSA reduction > 50%.Median rPFS was 18 months. Univariate analysis identified as significant variables: PSA, BPI, Gleason, node involvement, 4 weeks PSA reduction > 50%, and total volume of lymph node metastasis. On multivariate analysis, BPI (0-1 vs 2-3) (hazard ratio [HR] 1.81; p = 0.039), Gleason ( < 8 vs > = 8) (HR 2.51; p = 0.005), node involvement (no nodes, nodes < 3 cm and at least 1 node > = 3 cm (HR 2.8; p = 0.001 and 3.57; p = 0.009) and PSA reduction > 50% (HR 3.06; p < 0.001) were independently associated with rPFS. Median rPFS was superior in pts with 3 or more good prognostic factors (14m vs not reached; p < 0.001). Conclusions: BPI, Gleason, node involvement and 4-week PSA response were identified as independent prognostic factors for rPFS in first line AA treated patients. Clinical trial information: NCT02036060.
Interleukin 10 secretion in relation to human IL-10 locus haplotypes (1998)

Stimulation of human blood cultures with bacterial lipopolysaccharide (LPS) shows large inter-individual variation in interleukin 10 (IL-10) secretion, which has been shown to have a genetic component of over 70%. Alleles at two microsatellite loci in the 4 kb immediately upstream of the human IL-10 transcription initiation site in 132 individuals from 56 Dutch families were defined and assigned as haplotypes. LPS-induced IL-10 secretion was measured by ELISA and related to the IL-10 promoter haplotypes present in 78 unrelated individuals obtained from these families. Analysis showed that LPS-induced IL-10 secretion from unrelated individuals varied with IL-10 promoter haplotypes (P = 0.024; Kruskal-Wallis test). Two observations were made in relation to secreted IL-10 levels and promoter haplotypes; first, those haplotypes containing the allele IL10.R3 were associated with lower IL-10 secretion than haplotypes containing any other IL10.R allele. Second, the haplotype IL10.R2/IL10.G14 was associated with highest IL-10 secretion overall, whereas the haplotype IL10.R3/IL10.G7 was associated with lowest IL-10 secretion. These data demonstrate that the ability to secrete IL-10 can vary in man according to the genetic composition of the IL-10 locus.
Fatty acid, sterol and hydrocarbon composition of Antarctic sea ice diatom communities during the spring bloom in McMurdo Sound (1993)

The lipid composition of microalgal communities dominated by diatoms collected from the sea ice at three locations within McMurdo Sound during the austral spring bloom of 1989/90, was determined using gas chromatography (GC) and GC mass spectrometry. A range of C 27 -C 29 sterols were detected. The major sterols found at the three sites were 24-methylcholesta-5, 22E-diene-3β-ol (Cape Armitage); trans -22-dehydrocholesterol, 24-ethylcholesterol and 24-methylenecholesta (Erebus Ice Tongue); and 24-methylenecholesterol (Cape Royds). The difference in sterol profiles is believed to reflect the differing species composition at each site. The high relative levels (as % of total) of 24-ethylcholesterol at the Erebus Ice Tongue site (possibly related to Amphiprora kufferathii ) supports the proposal that diatoms are a more probable source of C 29 sterols in Antarctic lakes than are other algal groups or cyanobacteria. Changes in sterol composition over the course of the bloom were evident at the Cape Armitage site, particularly within the cellular free-lipid fraction. The major fatty acids identified were 14:0, 16:0, 16:1ω7c, 16:4ω1 and 20:5ω3 (Cape Armitage and Erebus Ice tongue sites); 16:0, 16:1ω7c and 20:5ω3 (Cape Royds site). All sites demonstrated high levels of PUFA (40–50% of total fatty acids), with an average 20:5ω3 level of 21% Erebus Ice Tongue, 20% Cape Royds, and 17% Cape Armitage. Variation was also observed in the percentage of 20:5ω3 for the Cape Armitage community over the sampling period. Levels of 22:6ω3 were between 0.4 and 1% of total fatty acids for the three sites. A C 25:2 isoprenoid hydrocarbon was present in samples from all sites, adding further evidence to the proposal that diatoms are probably a source of this and related isoprenoid alkenes in marine and coastal sediments.
ChemInform Abstract: Flux Synthesis, Crystal Structure, and Photoluminescence of a Heterometallic Uranyl‐Europium Germanate with U=O—Eu Linkage: K<sub>4</sub> [(UO<sub>2</sub>)Eu<sub>2</sub>(Ge<sub>2</sub>O<sub>7</sub>)<sub>2</sub>]. (2013)

Abstract Crystals of the new title compound are synthesized from UO 3 , Eu 2 O 3 , and GeO 2 using a mixture of KF and MoO 3 as flux (Pt crucible, 950 °C, 48 h).
Sparse feature extraction for model-less robust face pose estimation (2017)

Head pose estimation has been a focus of research in computer vision both implicitly in tasks that use full body pose estimation, and explicitly in tasks that perform face tracking and face recognition. One of the main problems in the field of face recognition techniques is the difficulty of handling varying poses. In this work, we propose a robust pose estimation approach that represents the relationship between the features of the face and the corresponding labels through a sparse representation. The discrimination of this representation is enhanced by projecting to a new space, pushing similar samples closer to each other. Experiment results are provided to show the robustness and accuracy of our approach.
Nitrous Oxide Control in the Dental Operatory: Auxiliary Exhaust and Mask Leakage, Design, and Scavenging Flow Rate as Factors (1996)

Abstract Two new local exhaust systems, intended primarily to control patient mouth emissions of N2O, were installed in a dental operatory, and resulting exposure concentrations to dental personnel were observed. The exposures were found to be typically unaffected by the presence and operation of these new controls. Laboratory testing on a head form, in conjunction with the operatory observations, established that mask leakage due to poor fit was the primary cause of N2O emissions. An improved mask fit and the addition of a slotted skirt around the outer mask shell individually resulted in greatly reduced leakage rates in the laboratory tests. Also, exhaust systems placed on the chin, on the chest, or in the mouth proved effective in capturing mouth emissions simulated by a breathing machine and head form. Keywords: dental operatorylocal exhaust systemsnitrous oxide
Competition between sulfur extrusion and thermal synthesis of thienocyclobutadiene in the pyrolysis of cis- and trans-1,2-diethynylthiiranes. Dimerization of the rearrangement product to bisthienocyclooctatetraene (1973)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCompetition between sulfur extrusion and thermal synthesis of thienocyclobutadiene in the pyrolysis of cis- and trans-1,2-diethynylthiiranes. Dimerization of the rearrangement product to bisthienocyclooctatetraeneK. Peter C. Vollhardt and Robert G. BergmanCite this: J. Am. Chem. Soc. 1973, 95, 22, 7538–7539Publication Date (Print):October 1, 1973Publication History Published online1 May 2002Published inissue 1 October 1973https://pubs.acs.org/doi/10.1021/ja00803a072https://doi.org/10.1021/ja00803a072research-articleACS PublicationsRequest reuse permissionsArticle Views140Altmetric-Citations38LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
ChemInform Abstract: NICKEL‐CARBON ADDITION TO THE COMPLEXED ALKENE (1983)

Abstract Die n5‐Cyelopentadienyl‐n3‐ethylen‐( cyclopropyl‐ bzw. phenyll‐nickel‐Komplexe (I) reagieren bei 20°C ′ bzw. ‐30°C (′ unter Addition der R‐Ni‐Bindtmg an das komplexierte Ethylen zu den Komplexen (ll ), die mit übersehüssigem Ethylen (III) als n5(yelopentadienyl‐nz‐ethylen‐(eyelopropylethylbzw.
ChemInform Abstract: THE SYNTHESIS, CHARACTERIZATION, AND REACTIVITY OF AN UNUSUAL, AMPHOTERIC (TETRAHYDROBORATO)RUTHENIUM HYDRIDE COMPLEX OF A CHELATING TRIPHOSPHINE, RU(H)(η2‐BH4)(TTP) (1982)

Abstract Die Behandlung des polymeren Ru(II)‐Komplexes (I) mit einem Überschuß an Na‐tetrahydridoborat führt zu dem Hydrido‐borato‐Komplex (II).
Amino acid residues in the transmembrane domain of the type 1 sigma receptor critical for ligand binding (1999)

The type 1 sigma receptor expressed in Xenopus oocytes showed binding abilities for the sigma-1 ligands, [3H](+)pentazocine and [3H]NE-100, with similar kinetic properties as observed in native tissue membranes. Amino acid substitutions (Ser99Ala, Tyr103Phe and di-Leu105,106di-Ala) in the transmembrane domain did not alter the expression levels of the type 1 sigma receptor as determined by immunoblot analysis using an anti-type 1 sigma receptor antiserum. By contrast, ligand binding was significantly suppressed by the substitutions. These findings provide evidence that the transmembrane domain of the type 1 sigma receptor plays a critical role in ligand binding of this receptor.
Effect of Thyroidectomy and Aminoglutethimide on Adrenal Function in Rats (1970)

Thyroidectomy caused a decrease in adrenal and ovarian weight and a decrease in the corticosterone secretion rate. Peripheral plasma levels of corticosterone were normal in resting conditions after thyroidectomy but decreased in surgical stress. Responses to aminoglutethimide after thyroidectomy were qualitatively of the same kind as in intact animals but quantitatively reduced. It is suggested that this was a manifestation of an impaired hypothalamo- pituitary-adrenal system, induced by thyroid deficiency, rather than a direct or specific dependence on thyroid hormones for action of the drug. (Endocrinology87: 1088, 1970)
New frontiers: self-assembly and nanoelectronics (2001)

In the quest for new semiconductor materials and processes, researchers focus on self-assembly, a concept that draws from diverse disciplines like chemistry, biology, material science, and electrical engineering. The following areas are examined: information theory; thermodynamics, synergetics and self-assembly; ribosome based lithography; nanofabrication by self-assembly; molecular electronics; and smart matter.
Rearrangement of PPARγ in a thyroid adenoma without 2q13 involvement: evidence for a breakpoint hot spot within the close surrounding of PPARγ? (2005)

In benign thyroid tumours main cytogenetic subgroups characterized by trisomy 7 and by rearrangements of either 19q13 or 2p21, respectively, have been described. Recently, we had been able to describe a novel gene called THADA (thyroid adenoma associated) affected by translocations involving chromosomal band 2p21. THADA is rearranged in benign thyroid tumors leading to a THADA-fusion gene in which the 3'-part is truncated and ectopic sequences derived from the translocation partners are fused to THADA. Other fusion genes found in thyroid tumours are RET/PTC2 and PAX8/PPARγ. The latter is caused by a translocation t(2;3)(q13;p25). Apart from PAX8/PPARγ rearrangements the chromosomal region 3p25 where PPARγ maps to is frequently affected by rearrangements in different thyroid tumours including papillary carcinomas, follicular carcinomas, and follicular adenomas, indicating that this region seems to be a breakpoint hot spot region.
Injecting Botulinum Toxin at Different Depths Is Not Effective for the Correction of Eyebrow Asymmetry (2014)

Because of the diffusion of the BoNT-A between muscle layers, the eyebrow depressor muscles cannot be accurately targeted with deep injection into the muscle belly for correction of eyebrow height discrepancies.
Rhythmic Bursting in the Cortico-Subthalamo-Pallidal Network during Spontaneous Genetically Determined Spike and Wave Discharges (2005)

Absence seizures are characterized by impairment of consciousness associated with bilaterally synchronous spike-and-wave discharges (SWDs) in the electroencephalogram (EEG), which reflect paroxysmal oscillations in thalamocortical networks. Although recent studies suggest that the subthalamic nucleus (STN) provides an endogenous control system that influences the occurrence of absence seizures, the mechanisms of propagation of cortical epileptic discharges in the STN have never been explored. The present study provides the first description of the electrophysiological activity in the cortico-subthalamo-pallidal network during absence seizures in the genetic absence epilepsy rats from Strasbourg, a well established model of absence epilepsy. In corticosubthalamic neurons, the SWDs were associated with repetitive suprathreshold depolarizations correlated with EEG spikes. These cortical paroxysms were reflected in the STN by synchronized, rhythmic, high-frequency bursts of action potentials. Intracellular recordings revealed that the intraburst pattern in STN neurons was sculpted by an early depolarizing synaptic potential, followed by a short hyperpolarization and a rebound of excitation. The rhythmic hyperpolarizations in STN neurons during SWDs likely originate from a subpopulation of pallidal neurons exhibiting rhythmic bursting temporally correlated with the EEG spikes. The repetitive discharges in STN neurons accompanying absence seizures might convey powerful excitation to basal ganglia output nuclei and, consequently, may participate in the control of thalamocortical SWDs.
An IC architecture for board-level mixed-signal test support (2002)

This paper investigates the use of mixed-signal test support ICs to extend a digital, board level test infrastructure to the analog section of a mixed-signal board. The architecture of a prototype test support IC is described and its application to the test of an infrared emitter-receiver board is discussed.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Cultured endothelial cell mobilization induced by partially purified human uterine angiogenic factor (1992)

The mobilization of endothelial cells may be induced by a number of external factors, and represents one step in a sequence of events which occurs during angiogenic stimulation. In vitro endothelial cells can organize and form a three-dimensional capillary network [1]. This process entails cellular motility.
The Ontogeny of Bladder Function in the Fetal Calf (1995)

Although numerous experimental studies have addressed urinary bladder physiology and pharmacology, little information is available concerning the ontogeny of bladder function. The present in vitro study describes the developmental aspects of bladder compliance, pressure generation and emptying in bovine fetuses from early second trimester to term (280 days). The results can be summarized as follows: 1) bladder compliance increased 3-fold between early second trimester and term; 2) sustained contractile response to bethanechol was present in all bladders; 3) field stimulation produced a submaximal, nonsustained contraction and an active relaxation when the field stimulus was turned off; 4) bladder emptying in response to bethanechol was nearly 100% in mid- and late-gestational bladders but was only 50% at early gestation; 5) bladder emptying in response to field stimulation was 20% to 40% for all gestational age groups; 6) field stimulated relaxation was observed only in the fetal bladder. These studies demonstrate that bladder physiology in utero is different from postnatal bladder function. The presence of a relaxant response during the fetal period may reflect a unique and significant role of the in utero bladder in protecting the upper urinary tracts from sustained increased pressure.
<sup>17</sup>O‐NMR‐Spektroskopie von Benzoylverbindungen YC<sub>6</sub>H<sub>4</sub> COX: Empfindlichkeit auf Substituenteneinflüsse als Maß für den Elektronenmangel an der Carbonylgruppe (1990)

Entgegen einer weit verbreiteten Meinung ist die 13 C‐NMR‐Spektroskopie nicht zur Ermittlung von Elektronendichte am Carbonyl‐C‐Atom geeignet. Durch Messung der 17 O‐chemischen Verschiebung bei aromatischen Carbonylverbindungen Y‐C 6 H 4 ‐COX, X = CF 3 , H, CH 3 , CO 2 R, Br, Cl, F, OCOAryl, SR, OR, NH 2 , OH, O ⊖ , konnten jedoch verläßliche Aussagen über die Elektrophilie des Carbonyl‐C‐Atoms gemacht werden. Es ist beruhigend, daß die Ergebnisse in Einklang mit klassischen chemischen Regeln sind. Vieles spricht dafür, der 17 O‐NMR‐Spektroskopie mehr Aufmerksamkeit zu schenken.