gebhart/patrepeval huggingface dataset:
Fused Ring Systems from Dieneynes. VI.<sup>1</sup> Some Limitations of the Cyclization Reaction (1937)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTFused Ring Systems from Dieneynes. VI.1 Some Limitations of the Cyclization ReactionP. S. Pinkney and C. S. MarvelCite this: J. Am. Chem. Soc. 1937, 59, 12, 2669–2672Publication Date (Print):December 1, 1937Publication History Published online1 May 2002Published inissue 1 December 1937https://pubs.acs.org/doi/10.1021/ja01291a057https://doi.org/10.1021/ja01291a057research-articleACS PublicationsRequest reuse permissionsArticle Views56Altmetric-Citations12LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Letter to the Editor (2010)

With great interest we read the paper by Kang et al 1 on the analgesic effects of ketamine infusion therapy in Korean patients with neuropathic pain.Since 1994, various articles based on case reports, pilot studies, and clinical trials have documented the value and tolerability of ketamine for the treatment of neuropathic pain states. 2 Due to its unique mechanism of action, ketamine is a highly interesting drug for treatment-resistant neuropathic pain syndromes, administered via various routes.Long periods of decreased pain can be triggered by relatively short courses of infusion.Dutch anesthesiologists found that complex regional pain syndrome type 1 (CRPS-1) patients with severe pain treated for 4 days with a continuous infusion of low-dose S-ketamine (N = 30) had a clinically relevant and statistically significant reduction in pain lasting for up to 11 weeks compared with patients receiving placebo (P < 0.001).However, one of the troublesome clinical aspects of treatment using intravenous ketamine is the reemergence of pain after some weeks and, therefore, the necessity to readminister treatment. 35][6][7] In a 2009 double-blind, placebo-controlled, crossover study, ketamine 10% in pluronic lecithin organogel was associated with alleviating allodynia in CRPS-1 patients without detectable blood levels of ketamine. 8This might suggest a topical mechanism of action, or a suboptimal dose regimen.In our clinic, we gained experience prescribing 10% racemic ketamine cream in CRPS-1 patients with treatment-refractory pain.Anecdotally, we have noted significant pain reduction with this intervention without additional adverse effects, including without negative effects on blood pressure.Well-designed studies evaluating the use of a topical 10% ketamine cream are necessary, as such treatment may be more easily tolerated and less expensive than ketamine infusion therapy.
A curious thing (2008)

Many of us who have had an influenza infection will know that we aren’t at our sharpest mentally when ill with flu. So, when I and other psychiatry researchers were invited by virology colleagues to test this hypothesis, we jumped at the opportunity. Twenty healthy volunteers were quarantined for 10 days and infected with influenza virus. We administered a number of validated neuropsychological tests assessing various aspects of …
Preparation of PZT Deposited Films by Using an Aerosol Jet Printing System and their Electric Properties. (1995)

PZT
The Pop-Gun Plot (1989)

The so-called Pop-Gun Plot involved five members of the London Corresponding Society: John Smith, a bookseller, of Portsmouth Street, Lincoln's Inn Fields; George Higgins, a chemist's shopman, of Fleet Market, nowadays Fleet Street; Paul Thomas Le Maitre, a watchmaker, of Denmark Street, Soho; Thomas Upton, also a watchmaker, of Bell Yard, Temple Bar; and Robert Thomas Crosfield (1768–1802), of no fixed abode. Although all were arrested after an investigation by the Privy Council, Crosfield alone faced the ordeal of a trial for high treason. Parkinson appeared for the defence both before the Privy Council and at the trial.
Myelolipoma of the Kidney (1974)

No AccessJournal of Urology1 Jul 1974Myelolipoma of the Kidney Dan Beraha, Norman L. Block, and Victor A. Politano Dan BerahaDan Beraha , Norman L. BlockNorman L. Block , and Victor A. PolitanoVictor A. Politano View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)59632-9AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail © 1974 by The American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetailsCited bySneiders A, Zhang G and Gordon B (2018) Extra-Adrenal Perirenal MyelolipomaJournal of Urology, VOL. 150, NO. 5 Part 1, (1496-1497), Online publication date: 1-Nov-1993. Volume 112Issue 1July 1974Page: 19-21 Advertisement Copyright & Permissions© 1974 by The American Urological Association Education and Research, Inc.MetricsAuthor Information Dan Beraha More articles by this author Norman L. Block More articles by this author Victor A. Politano More articles by this author Expand All Advertisement PDF downloadLoading ...
Quantification of liver fat in the presence of iron overload (2016)

1 J. Magn. Reson. Imaging 2017;45:428-439.
Determining Bayesian evidence and decay time estimates in acoustically coupled volumes (2006)

Sound energy decay analysis is an important element in understanding acoustical properties of coupled volumes in architectural acoustics. A Bayesian model formulation using Monte Carlo algorithms [Xiang and Goggans, J. Acoust. Soc. Am. 110 1415–1424 (2001); Jasa and Xiang, ibid. 117, 3707(A) (2005)] has been applied to estimating both the decay times and decay order required in sound energy decay analysis. The need to focus on model selection in a Bayesian model formulation of sound energy decay analysis was presented by Jasa and Xiang [J. Acoust. Soc. Am. 119, 3343(A) (2006)] along with a discussion of the limitations of the existing Monte Carlo algorithms used for this purpose. This paper will present some recent algorithms that can overcome the limitations of a Monte Carlo approach to model selection and show how these algorithms can be applied to determining both the proper model and decay time estimates for acoustically coupled rooms.
ChemInform Abstract: Synthesis of 1,1‐Dioxopenicillanoyloxymethyl 6‐[D‐α‐(Benzylideneaminophenylacetamido)]penicillanate and Analogues. New Intermediates in the Preparation of Sultamicillin. (2001)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Liquid phase growth of epitaxial Ni and Co silicides (1983)

Epitaxial Ni and Co silicides have been fabricated using pulsed laser melting and ultrarapid solidification techniques. Interfacial instabilities and cell formation are suppressed during the liquid phase epitaxy by melting mono or disilicide layers. Single crystal NiSi2 and CoSi2 films have been grown on (100) and (111) Si. This method does not require ultrahigh vacuum deposition or reaction techniques.
Inhibition of spinal opioid antinociception by intrathecal β‐endorphin<sub>1–27</sub> in the rat (1993)

1. The effects of intrathecal (i.t.) administration of beta-endorphin and two shorter fragments, human and ovine beta-endorphin1-27, were examined for antinociceptive activity in the tail-flick and paw-pressure tests in the rat. Additionally, the ability of ovine beta-endorphin1-27 to influence the action of i.t. beta-endorphin, morphine and [D-Pen2-D-Pen5]enkephalin (DPDPE) was also examined in these tests. 2. After i.t. injection, beta-endorphin produced potent dose-related antinociception in the tail-flick and paw-pressure tests. Shorter endorphins produced much weaker effects. The order of antinociceptive efficacy was beta-endorphin > human beta-endorphin1-27 > ovine beta-endorphin1-27. 3. Administration of ovine beta-endorphin1-27 (0.72, 1.44 nmol, i.t.) significantly attenuated the antinociceptive effect of beta-endorphin (2.88 nmol, i.t.) in the tail-flick and paw-pressure tests. 4. Both i.t. morphine and DPDPE produced dose-related antinociception in the tail-flick and paw-pressure tests. The potency of DPDPE was lower than that of morphine in both tests; however, the effect of DPDPE was weaker in the paw-pressure test. 5. Administration of ovine beta-endorphin1-27 (1.44 nmol, i.t.) significantly attenuated the antinociceptive effect of morphine (14.9 nmol, i.t.) in both tests and the effect of DPDPE (38.7 nmol) in the tail-flick test. 6. The results show that beta-endorphin1-27 acts as an opioid antagonist at the spinal level in the rat. Its ability to inhibit the action of morphine and DPDPE suggests that it may attenuate beta-endorphin action by an interaction with mu- and/or delta-opioid receptors.
Yes -- Neural Network Learning Theory Can Resolve the Behavioral Cognitive Controversy (1996)

The positive comments and constructive ton with which Forsyth, Hawkins, and Hutchinson (1996) begin their response to Tryon's (1993b, 1995a, 1995b) thesis that Neural Network Learning Theory (NNLT) can resolve the behavioral cognitive controversy identifies consistencies between Radical Behaviorism (RB) and connectionistic Neural Network Learning Theory (NNLT). The questions they raise in subsequent sections are important to achieving rapprochement of the cognitive behavioral schism and are therefore addressed here. The primary task of unification is to combine the positive contributions of both the behavioral and cognitive perspectives without rejecting or compromising important values of either orientation. For reasons presented below, I conclude the NNLT, which is completely compatible with cognitive psychology, is also theoretically compatible with behavior analysis and will broaden the appeal of behavioral analysis within the scientific community.
Poly(β‐hydroxyalkanoates): Biorefinery polymers in search of applications (1988)

Abstract Poly(β‐hydroxyalkanoates) are nature's high molecular weight thermoplastic polyesters. They occur as storage granules in a variety of bacteria. From a plastics, film, and fibres perspective, the statistically random copolyesters based on β‐hydroxybutyrate (HB) and β‐hydroxyvalerate (HV) repeating units have high potential for commercial exploitation because of their biodegradability. They provide a range of melting points from 180°C down to 80°C and all compositions exhibit high crystallinity due to isodimorphism. The latter is due to the similar crystalline conformations of poly(β‐hydroxybutyrate) (PHB) and poly(β‐hydroxyvalerate) (PHV). The nascent granules of a 21 mole % HV copolyester sample in freeze‐dried bacterial cells were examined by 13 C solid‐state NMR. A disorder in the HV ethyl side group was noted but backbone carbons for HB and HV units showed evidence of crystalline order which was confirmed by x‐ray diffraction. In keeping with the isodimorphous properties of this system, electron diffraction of copolyester single crystals for compositions up to 21 mole % HV confirmed a lattice expansion previously observed for bulk crystallized P(HB‐co‐HV). Solution or melt crystallized films showed decreasing rates of crystallization with increasing HV content. Homogeneous blends of PHB with P(HB‐co‐HV) could be formed which showed a single melting peak by differential scanning calorimetry. The potential of P(HB‐co‐HV) as a source of value‐added small molecules is discussed. Depending on the method of degradation (i.e., chemical or pyrolytic) chiral synthons or vinylic small molecules are obtainable in nearly quantitative yields. Because their physical properties resemble those of polyolefins this family of chiral thermoplastics will probably find wide use in biomedical applications where compatibility and absorbability are essential features.
First Synthesis and Characterization of CH<sub>4</sub>@C<sub>60</sub> (2019)

The endohedral fullerene CH<sub>4</sub> @C<sub>60</sub> , in which each C<sub>60</sub> fullerene cage encapsulates a single methane molecule, has been synthesized for the first time. Methane is the first organic molecule, as well as the largest, to have been encapsulated in C<sub>60</sub> to date. The key orifice contraction step, a photochemical desulfinylation of an open fullerene, was completed, even though it is inhibited by the endohedral molecule. The crystal structure of the nickel(II) octaethylporphyrin/ benzene solvate shows no significant distortion of the carbon cage, relative to the C<sub>60</sub> analogue, and shows the methane hydrogens as a shell of electron density around the central carbon, indicative of the quantum nature of the methane. The <sup>1</sup> H spin-lattice relaxation times (T<sub>1</sub> ) for endohedral methane are similar to those observed in the gas phase, indicating that methane is freely rotating inside the C<sub>60</sub> cage. The synthesis of CH<sub>4</sub> @C<sub>60</sub> opens a route to endofullerenes incorporating large guest molecules and atoms.
Screen-printed electrodes modified with HRP-zirconium alcoxide film for the development of a biosensor for acetaminophen detection (2010)

Abstract The development of a biosensor based on the immobilization of horseradish peroxidase (HRP) within a zirconium alkoxide-polyetilenimine film onto screen-printed electrodes (SPE) for acetaminophen detection and acetaminophen quantification in pharmaceutical products is described. The biosensor operation mode is based on monitoring the amperometric signal produced by the electrochemical reduction of the enzymatically generated electroactive oxidized species of acetaminophen in the presence of hydrogen peroxide. The enzyme immobilization is performed by retention in a polyethylenimine-zirconium alcoxide porous gel film, a technique that offers good entrapping and a protective environment for the biocomponent due to the hydration properties of the immobilization layer. SPEs have the advantage of being easily mass-produced at low costs with superior characteristics in comparison with classical electrode materials. In this configuration, zirconium alkoxide demonstrates its electrocatalytic activity. The biosensor allows the quantification of acetaminophen with a limit of detection of 6.21×10−8 M and a linear range between 4.35×10−7 M and 4.98×10−6 M. Finally, the biosensor is applied to the quantitative analysis of acetaminophen in Perdolan® tablets.
Endovascular treatment strategy for direct carotid-cavernous fistulas resulting from rupture of intracavernous carotid aneurysms. (2003)

Although other techniques using a transvenous approach and/or detachable coils may also be useful, embolization with detachable balloons should be a safe and effective method to immediately occlude the fistula.
Light-matter excitations in the ultra-strong coupling regime (2008)

In a microcavity, light-matter coupling is quantified by the vacuum Rabi frequency $\Omega_R$. When $\Omega_R$ is larger than radiative and non-radiative loss rates, the system eigenstates (polaritons) are linear superposition of photonic and electronic excitations, a condition actively investigated in diverse physical implementations. Recently, a quantum electrodynamic regime (ultra-strong coupling) was predicted when $\Omega_R$ becomes comparable to the transition frequency. Here we report unambiguous signatures of this regime in a quantum-well intersubband microcavity. Measuring the cavity-polariton dispersion in a room-temperature linear optical experiment, we directly observe the anti-resonant light-matter coupling and the photon-energy renormalization of the vacuum field.
Meridian UAV Flight Performance Analysis Using Analytical and Experimental Data (2009)

The Center for Remote Sensing of Ice Sheets (CReSIS) is a Science and Technology Center established by the National Science Foundati on (NSF) in 2005, with the mission of developing new technologies and computer models to measure and predict the response of sea level change to the mass balance of ice sheets in G reenland and Antarctica. The CReSIS is developing sophisticated sensors and long-duration inhabitant aerial vehicle (UAV) which is called the Meridian. This paper presents the Meridi an flight performance analysis. A simulation model of the Meridian was developed using Advanced Aircraft Analysis (AAA) software. Using the AAA model stability derivatives and performance analysis were also. To validate the AAA results a parallel performance analysis was conduct ed using analytical methods and experimental data. Two different analytical methods were used f or the performance analysis; this helped to check the validity of the AAA results.
A PROTECTIVE ROLE FOR NATURAL IGM ANTIBODIES TO PHOSPHORYLCHOLINE IN CARDIAC TRANSPLANT RECIPIENTS (2010)

1Imperial College London, London/UNITED KINGDOM, 2National Heart And Lung Institute, Imperial College London, London/UNITED KINGDOM
Distribution of Radioactivity in Body Fat and Organs of Rats Treated with Labeled Quinestrol, Ethynylestradiol or 17 -Estradiol. (1967)

SummaryThe distribution of radioactivity in body fat and organs, 24 hours after administration of radiolabeled ethynylestradiol-3-cyclopentyl ether (EECPE), ethynylestra-diol (EE) and 17 β-estradiol (E2) has been studied in castrated female rats. Radioactivity was highest in various types of fat of EECPE-treated animals. Only 1/10-1/30 as much tritium was detected in fat of rats treated with EE or E2. Each steroid exhibited an individual preference for each particular type of fat. Concentration of steroid in the various organs did in general correspond to the amount of fat present. Free (ether soluble) metabolites were in general more concentrated in organs than in plasma whereas water soluble metabolities (presumably conjugates) were generally higher in plasma than in the various organs. The data on the 3H/14C ratio suggests that the 14C labeled cyclopentyl group is cleaved from EECPE and eliminated via the kidney at a faster rate than the steroid moiety. The distribution of radioactivity in different br...
A Method Applicable to the Standardization of Influenza Virus Vaccines. (1947)

A procedure applicable to the standardization of influenza virus vaccines has been described. The total time required for completion of the test can be as little as 16 days. The procedure, referred to as the anti-genic extinction titration, determines the highest dilution of antigen capable of inducing the formation of demonstrable amount of virus-neutralizing antibody in the pooled serum of groups of 10 mice. The test for neutralizing antibody is carried out in ovo and may; therefore, be used in those instances in which the strain of virus that may be included in a vaccine has been adapted only to the chick embryo and is not pathogenic for mice.
Complete Sequence of a <i>bla</i> <sub>KPC</sub> -Harboring Cointegrate Plasmid Isolated from Escherichia coli (2015)

Horizontal transfer of bla(KPC)-harboring plasmids contributes significantly to the inter- and intraspecies spread of Klebsiella pneumoniae carbapenemase (KPC). Here we report the complete nucleotide sequence of a bla(KPC)-harboring IncFIA plasmid, pBK32533, from Escherichia coli. pBK32533 is a cointegrate plasmid comprising of a 72-kb sequence identical to that of the nonconjugative pBK30661 plasmid plus an additional 170-kb element that harbors the genes for plasmid transfer. pBK32533 demonstrates how bla(KPC) can be spread from a nonconjugative plasmid through cointegration.
Normotensive and hypotensive closed-loop resuscitation using 3.0% NaCl to treat multiple hemorrhages in sheep* (2006)

Volume sparing was apparent with HS, but no hemodynamic or metabolic advantage was apparent when used for either normotensive or hypotensive resuscitation. Trends toward lower base excess values and higher occurrences of deaths only in the hypotensive treatment protocols suggest that resuscitation to a target mean arterial pressure of 65 mm Hg may be too low.
Robust Stabilization and Disturbance Rejection for Uncertain Systems by Decentralized Control (1990)

This paper develops a decentralized control design which provides robust H ∞ disturbance rejection for a plant with structured uncertainty in a bounded admissible set. The design consists of an observer in each control channel, which includes estimates of the controls generated in the other channels and of the worst disturbance as determined by a state-feedback H ∞ solution. The observer gains are computed from a positive-definite solution of a Riccati-like algebraic equation. A convexity property of a matrix Riccati function is used to compute for the closed-loop system an H ∞-norm bound smaller than the predetermined bound, and to find an enlarged admissible set of plant uncertainities.
Host Genotype Effects on Inoculum Production by Cephalosporium gramineum from Infested Residue (1990)

(...) Straw from Plainsman V supported the production of inoculum at a level similar to that observed for Sturdy, whereas straw from Arkan supported a level of inoculum midway between those of Sturdy and Newton. Inoculum production was not related to the resistance response of the cultivar: Sturdy is highly susceptible, and Newton and Plainsman V are moderately resistant. These results suggest that Cephalosporium stripe decline induced by monoculture of moderately resistant cultivars is not the result of reduced ability of the infested residue of these cultivars to produce inoculum
Constitutive modelling of Sandvik 1RK91 (2003)

A physically based constitutive equation is being developed for the maraging stainless steel Sandvik 1RK91. The steel is used to make precision parts. These parts are formed through multistage forming operations and heat treatments from cold rolled and annealed sheets. The specific alloy is designed to be thermodynamically unstable, so that deformation even at room temperatures can bring about a change in the phase of face centred cubic austenite to either hexagonal closed packed martensite and/or, body centred cubic martensite. This solid state phase change is a function of the strain path, strain, strain rate and temperature. Thus, the fraction of the new phase formed depends on the state of stress at a given location in the part being formed. Therefore a set of experiments is being conducted in order to quantify the stress-strain behavior of this steel under various stress states, strain, strain rate as well as temperature. A magnetic sensor records the fraction of ferromagnetic martensite formed from paramagnetic austenite. A thermocouple as well as an infra red thermometer is used to log the change in temperature of the steel during a mechanical test. The force-displacement data are converted to stress-strain data after correcting for the changes in strain rate and temperature. These data are then cast into a general form of constitutive equation and the transformation equations are derived from Olson-Cohen type functions.
TENDON REPAIRS WITH NYLON AND A MODIFIED PULLOUT TECHNIQUE (1971)

MANGUS, DONALD J. M.D.1; BROWN, FAYETTE M.S.2; BYRNES, WILLIAM M.D.1; HABAL, AYMEN3 Author Information