gebhart/patrepeval huggingface dataset:
Spectra and structure of chiral molecules. III.a) Vibrational assignment and normal coordinate analysis of 1-bromo-1-chloro-1-fluoroethane and 1-bromo-1-chloro-1-fluoroethane?2-<i>d</i>1 (1978)

The infrared spectra (3100–200 cm−1) of the gaseous, neat solid and argon matrix, and the Raman spectra of the liquid and solid states are reported for 1-bromo-1-chloro-1-fluoroethane and for the three conformations of 1-bromo-1-chloro-1-fluoroethane-2-d1. Forty-seven distinct frequencies were used to calculate a generalized valence force field (GVFF) and a Urey–Bradley (UBFF) force field.
Genesis and maintenance of &quot;Mediterranean hurricanes&quot; (2005)

Abstract. Cyclonic storms that closely resemble tropical cyclones in satellite images occasionally form over the Mediterranean Sea. Synoptic and mesoscale analyses of such storms show small, warm-core structure and surface winds sometimes exceeding 25ms-1 over small areas. These analyses, together with numerical simulations, reveal that in their mature stages, such storms intensify and are maintained by a feedback between surface enthalpy fluxes and wind, and as such are isomorphic with tropical cyclones. In this paper, I demonstrate that a cold, upper low over the Mediterranean can produce strong cyclogenesis in an axisymmetric model, thereby showing that baroclinic instability is not necessary during the mature stages of Mediterranean hurricanes.
Mems-based sonoporation devices for intratumoral gene therapy (2005)

This paper presents a miniature device for intratumoral delivery of oligonucleotides (ASO). A PZT plate (1 cm/sup 2/ /spl times/ 0.75mm) is used to transfect cells using cavitation-induced sonoporation. Both human umbilical vein endothelial cells (HUVEC) and human prostate cancer cells (PC3) are investigated in vitro. Preliminary results show that after cavitation-induced sonoporation, the transfection rate for HUVEC increases by 10% compared to controls (p<0.01). For PC3, the transfection rate increases by 7% compared to controls (p<0.01).
Color segmentation for scene exploration (2000)

In this contribution we describe the results of the color structure code algorithm and a modified split and merge algorithm, which both segment a color image into regions. We integrate these algorithms into our system for knowledge–based image analysis and compare the two distinct methods concerning their applicability in our system for knowledge-based exploration of a scene. 1
Dietary Modifications of Nitrogen Intake Decreases Inflammation and Promotes Rejuvenation of Spleen in Aged Mice (2018)

The spleen is a lymphoid organ with multiple functions including blood filtration and immune activity. Aging changes the spleenâs anatomy for both immune and stromal cells and can lead to immunesenescence, contributing to the increased rates of mortality and morbidity commonly observed in the elderly. Much evidence indicates that the combination of food quantity and quality can influence chronic inflammatory states in the spleen. Quantitative amino-acids (AA) adequacy is pivotal to maintain cell integrity in mammals. Aged mice feed with balanced essential-AA (EAA) formulation improved mitochondrial biogenesis and morphological and molecular changes in many organs, as well as increased lifespan. Here, we evaluated the inflammatory state of the spleen in aged male mice (fifteen months old) chronically fed for twelve months with a particular EAA-rich diet compared to a standard laboratory diet. This study found that chronic consumption of an EAA-rich diet decreased inflammation and modulated reticular and mitochondrial chaperones, mitochondrial function and cells survival, maintaining the correct architecture of the spleen. These changes could also be beneficial for immune system integrity, providing a possible theoretical-speculative basis for the role of EAA improving the quality of life of the elderly by probably slowing immune-senescence.
Photobleaching with phloxine B sensitizer to reduce food matrix interference for detection of Escherichia coli serotype O157:H7 in fresh spinach by flow cytometry (2013)

A flow cytometric method (RAPID-B™) with detection sensitivity of one viable cell of Escherichia coli serotype O157:H7 in fresh spinach (Spinacia oleracea) was developed and evaluated. The major impediment to achieving this performance was mistaking autofluorescing spinach particles for tagged target cells. Following a 5 h non-selective enrichment, artificially inoculated samples were photobleached, using phloxine B as a photosensitizer. Samples were centrifuged at high speed to concentrate target cells, then gradient centrifuged to separate them from matrix debris. In external laboratory experiments, RAPID-B and the reference method both correctly detected E. coli O157:H7 at inoculations of ca. 15 cells. In a follow-up study, after 4 cell inoculations of positives and 6 h enrichment, RAPID-B correctly identified 92% of 25 samples. The RAPID-B method limit of detection (LOD) was one cell in 25 g. It proved superior to the reference method (which incorporated real time-PCR, selective enrichment, and culture plating elements) in accuracy and speed.
Absorption spectroscopy and binding constants for first-row transition metal complexes of a DOPA-containing peptide (2005)

A diverse array of biological systems incorporate 3,4-dihydroxyphenlyalanine (DOPA) into proteins and small molecules for cross-linking and material generation. Marine worm eggshells, sea squirt wound plugs, and marine mussel adhesives may all be formed by combining DOPA-containing molecules with high levels of metals. In order to provide model systems for characterizing these biomaterials, we carried out a study on metal binding to a DOPA-containing peptide. Ultraviolet-visible absorption spectra are presented for the AdopaTP peptide binding to Fe3+, V3+, VO2+, Mn3+, Ti4+, Cu2+, Co2+, and Ni2+ in mono, bis, and where applicable, tris coordination modes. Association constants were determined for selected metal ions binding to the peptide. In general, the spectroscopic and binding properties of this DOPA-containing peptide were found to be similar to those of catechol.
The United Kingdom Diabetic Retinopathy Electronic Medical Record Users Group, Report 1: baseline characteristics and visual acuity outcomes in eyes treated with intravitreal injections of ranibizumab for diabetic macular oedema (2016)

In a large cohort of eyes with DMO treated with ranibizumab injections in the UK, 33% of patients achieved better than or equal to 6/12 in the treated eye at 12 months compared with 25% at baseline. The mean visual gain was five letters. Eyes with excellent VA at baseline maintain good vision at 18 months.
Measurement of Deflection Distribution Using Phase-shifting Digital Holography (2002)

In this study, the deflection distribution of a cantilever is measured combining the holographic interferometry and phase-shifting digital holography. Holographic interferometry can measure with high accuracy, high sensitivity, and full-field by noncontacting. But the development processing of a film is troublesome by holographic interferometry. Digital holography record on CCD and it reconstructs it with a computer. Therefore, development processing is not needed and it is early reproducible by digital holography. Digital holography has the amplitudes information and phase information in digital information. By the holographic interferometer, the sum of complex amplitude before and after deformation is reconstructed. In this study, the sum of complex amplitude before and after deformation is calculated and reconstructed. Therefore, phase difference computed for digital information and the displacement of a nano-meter order will be able to measure with this method.
ChemInform Abstract: A Novel Process for Fabricating Conformal and Stable TiN‐Based Barrier Films. (1997)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Network-based Localized Mobility Management Interface between Mobile Node and Access Router (2006)

This document specify an IP layer interface between mobile nodes (MN)
and access routers (AR) of a network-based localized mobility
management (NetLMM) domain. Such an interface is subject to a certain
number of threats, amongst which are attacks on the mapping between
the MN Identifier and IPv6 address set. A binding enforcement
mechanism between those two is hence required to prevent malicious
nodes to carry on various attacks like service theft or denial-of-
service attacks. In the absence of link-layer specific mechanisms
enforcing this binding, it is required to implement such mechanism at
the IP layer MN-AR interface. Moreover, it is required that no NetLMM
specific software support is present on MNs. The IP layer MN-AR
interface described in this document fulfills these two requirements
by using the SEND public key as the MN identifier, while being solely
based on standard track IPv6 protocols (DNA and SEND) implemented by
non-NetLMM MNs.
Robust Backlash Estimation for Industrial Drive-Train Systems—Theory and Validation (2018)

Backlash compensation is used in modern machine-tool controls to ensure high-accuracy positioning. When wear of a machine causes deadzone width to increase, high-accuracy control may be maintained if the deadzone is accurately estimated. Deadzone estimation is also an important parameter to indicate the level of wear in a machine transmission, and tracking its development is essential for condition-based maintenance. This paper addresses the backlash estimation problem using sliding-mode and adaptive estimation principles and shows that prognosis of the development of wear is possible in both theory and practice. This paper provides the proof of asymptotic convergence of the suggested estimator, and it shows how position offset between motor and load is efficiently utilized in the design of a very efficient estimator. The algorithm is experimentally tested on a drive-train system with the state-of-the-art Siemens equipment. The experiments validate the theory and show that expected performance and robustness to parameter uncertainties are both achieved.
Building collaborative teams for multidisciplinary educational projects in optoelectronics (2000)

Multidisciplinary team-oriented research is an effective method for investigating systems spanning multiple knowledge areas. Building on cross-functional team strategies developed for highly competitive industries, experts from a variety of technical domains can be brought together in a team and focused toward a common set of goals. However, building and maintaining these teams is an art that combines technical, social, and management skills, and requires proactive, conscious attention to enable and achieve positive results. This paper explores some avenues toward effective multi-disciplinary team building, and explores the educational potential associated with team-oriented research.
Betriebstechnik der Rangierbahnhöfe (2011)

Im Gesamtsystem des Eisenbahnverkehrs stellt das Rangieren gegenüber dem Fahren der Züge nur einen Hilfsprozess dar (siehe Abschnitt 1.3.3). Durch den Übergang zum Wendezugbetrieb und das in Mitteleuropa abgesehen von einigen internationalen Verbindungen kaum noch übliche Verkehren von Kurswagen beschränken sich Rangierfahrten im Personenverkehr heute weitgehend auf das Bereitstellen und Abräumen der Zugeinheiten am Beginn und Ende des Zuglaufs, den Wechsel von Triebfahrzeugen und das Umsetzen von Fahrzeugen in den Nebengleisanlagen der Betriebswerke. Ähnlich ist die Situation im Güterverkehr in den Geschäftsfeldern des Ganzzugverkehrs und des kombinierten Ladungsverkehrs. Rangierfahrten finden fast nur im Bereich der Ladestellen in den Anschlussbahnen und Umschlagbahnhöfen sowie beim Triebfahrzeugwechsel statt.
Experimental Confirmation of Computed, Three-Dimensional Streaklines for Natural Convection in an Inclined Rectangular Enclosure (1979)

高さ3cm, 奥行3cm, 幅6cmの矩形容器の上方面を冷却, 下方面を加熱, 周囲を断熱した時の内部のグリセリンの自然対流流動形態を調べた.容器の水平方向の短辺あるいは長辺を傾け, トレーサーを入れてみた結果, 各傾斜角度において出現する自然対流のロールセルには, いずれの場合にも共軸二重らせん渦とでもいうべき流れが存在することがわかった.一般に2次元流れとみなされやすい短辺傾斜の場合においてさえロールの軸方向 (3次元方向) の流速は無視できないほどで, 壁近くの粒子は容器中央付近まで輸送されることがわかった.これらの知見は3次元数値解析に基づく長時間粒子軌跡図で予測される流動特性とまったく同じものと認められ, 箸者らの開発による3次元数値解析法を裏づけるものと考えられる.
Lipomas after blunt soft tissue trauma: are they real? Analysis of 31 cases (2007)

The existence of a pathogenic link between blunt soft tissue trauma and the formation of post-traumatic lipomas is still controversial. Two potential mechanisms are discussed. Firstly, the formation of so-called post-traumatic 'pseudolipomas' may result from a prolapse of adipose tissue through fascia induced by direct impact. Alternatively, lipoma formation may be explained as a result of preadipocyte differentiation and proliferation mediated by cytokine release following soft tissue damage after blunt trauma and haematoma formation.
High Tg aliphatic polyesters by the polymerization of spirolactide derivatives (2010)

A series of bicyclic and tricyclic lactide derivatives was prepared using L-lactide as the starting material. Exomethylene-lactide served as a platform for the Diels–Alder addition of various dienes to afford norbornene-, cyclohexadiene-, and isoprene-lactide derivatives. Norbornene-lactide (NL) was also hydrogenated to the saturated norbornane analog. These new lactide derivatives were subjected to ring-opening polymerization using 1,5,7-triazabicyclo[4.4.0]dec-5-ene (TBD) as the catalyst. Homopolymers of poly(cyclohexadiene-lactide) (Mn = 6.4 kg mol−1), poly(isoprene-lactide) (Mn = 15.3 kg mol−1), and poly(norbornane-lactide) (Mn = 34.4 kg mol−1) exhibited glass transition temperatures (Tg's) of 119 °C, 77 °C, and 107 °C, respectively. The decomposition temperature (Td) of unsaturated PLA derivatives was ≤280 °C, whereas saturated poly(norbornane-lactide) has a Td of 300 °C. Additionally, a series of poly(norbornene-lactide-s-L-lactide) (P(NL-s-L)) copolymers with varying ratios of NL and L-lactide were prepared. The Tg's of the P(NL-s-L) samples ranged from 61 to 100 °C, and the values were well-described by the Fox equation.
A computational approach to building gene silencing modules (2013)

The past decades pointed out RNA has alot of functions besides being an information carrier (mRNA). Small RNAs (e.g. antisense RNA) form an essential part of different prokaryotic regulatory mechanisms by, for example, blocking the ribosome binding site (RBS). As such sRNA can be used in synthetically constructed biological devices to silence a gene on demand. Tools and know how for model-based design of RNA molecules that efficiently block the RBS of a specific gene are however still underdeveloped. Here we present a method to design silencing modules that can efficiently block the translational process. This approach uses knowledge on antisense RNA to model the physical nature of this biological interaction. The available literature was used to identify potential characteristics of a good silencing sequence. Based on this information a bioinformatics framework was developed to enable a computational characterization of a potential silencing sequence. Herein, several dynamic programming algorithms are used to accurately predict these RNA-RNA interactions. The influence of the different defined features of the candidate sequences, which were semi-rationally generated and send through a preliminary in silico filter, was investigated. The performance of a group of selected candidate sequences are tested in vivo to determine their silencing capacities. As a test case, mRNA containing a red fluorescent protein was constructed using biofab parts. Based on these results the importance of the features is evaluated. Ultimately, this computational approach can be used for the design of tailor made silencing modules with excellent performance.
A case of a female infant with simultaneous occurrence of <i>de novo</i> terminal deletions on chromosome 14q and 20p (1993)

This is a case report on an infant with de novo terminal deletions on the long arm of chromosome 14 and on the short arm of chromosome 20 [46, XX, del(14)(q32)del(20)(p11)]. Examination revealed that the infant had a peculiar face, a cleft and high palate, abnormal dentition, butterfly-like vertebral defects, finger anomalies, a simian line on the left hand, talipes equinovarus, deep plantar furrows, abnormally high values of alkali phosphatase and lactate dehydrogenase, mild anemia and psychomotor retardation. Comparing the present case with previously reported cases of a single deletion on chromosome 14q or chromosome 20p, the infant showed some symptomatic and dysmorphic features of both deletions.
Cranial anatomy and detection of ischemic stroke in the cat by nuclear magnetic resonance imaging. (1982)

Proton nuclear magnetic resonance (NMR) images of cat heads were obtained using a small, experimental imaging system. As a prelude to the study of experimental ischemic brain infarction, the normal cat head was imaged for identification of anatomical features. Images of one cat which had undergone ligation of the middle cerebral artery three weeks previously showed brain changes associated with chronic ischemic stroke and compared favorably with findings on computed tomography (CT). The NMR images have millimetric spatial resolution. NMR parameters inherent in the tissues provide intensity variations and are sufficiently sensitive to yield contrast resolution surpassing that of CT.
The Effects of Direct Current Countershock on Ventricular Late Potentials (1987)

Signal averaging is a noninvasive method of recording ventricular late potentials. These late potentials are present in many patients with sustained ventricular tachycardia. Analysis of ventricular late potential characteristics may develop as a useful marker of antiarrhythmic drug efficacy. Often antiarrhythmic drugs are tested acutely in the electrophysiology laboratory after direct current countershock (DC shock). The purpose of this study was to investigate the effects of DC shock delivered for cardioversion of sustained ventricular tachycardia or fibrillation on ventricular late potentials. Signal averaged electrocardiograms (SAEKGs) were recorded before and after 13 DC shocks. There was no significant change in QRS duration, duration of the high frequency filtered QRS, or duration of the high frequency signal under 40 microvolts. There was a small increase in the root mean square amplitudes of the terminal 40 milliseconds (41 microV to 49 microV). This degree of change is felt to be clinically insignificant. Except for one trial, no late potential appeared or disappeared after electrical cardioversion. We have shown that ventricular late potentials are only slightly altered by programmed ventricular stimulation, induced sustained ventricular tachycardia or ventricular fibrillation, and DC countershock. To analyze changes in ventricular late potentials after antiarrhythmic drug administration in the electrophysiology laboratory, in those patients requiring DC countershock, comparisons should be made to postshock SAEKGs rather than those obtained prestudy.
Induction of 33-kD and 60-kD Peroxidases during Ethylene-Induced Senescence of Cucumber Cotyledons (1988)

Ethylene enhanced the senescence of cucumber (Cucumis sativus L. cv `Poinsett 76') cotyledons. The effect of 10 microliters per liter ethylene was inhibited by 1 millimolar silver thiosulfate, an inhibitor of ethylene action. An increase in proteins with molecular weights of 33 to 30 kilodaltons and lower molecular weights (25, 23, 20, 16, 12, and 10 kilodaltons) were observed in sodium dodecyl sulfate-polyacrylamide gel electrophoresis gels after ethylene enhanced senescence. The measurement of DNase and RNase activity in gels indicated that these new proteins were not nucleases. Two proteins from ethylene-treated cotyledons were purified on the basis of their association with a red chromaphore and subsequently were identified as peroxidases. The molecular weights and isoelectric points (pI) of two of these peroxidases were 33 kilodaltons (cationic, pI = 8.9) and 60 kilodaltons (anionic, pI = 4.0). The observation that [(35)S]Na(2)SO(4) was incorporated into these proteins during ethylene-enhanced senescence suggests that these peroxidases represent newly synthesized proteins. Antibodies to the 33-kilodalton peroxidase precipitated two in vitro translation products from RNA isolated from ethylene-treated but not from control cucumber seedlings. This indicates that the increase in 33-kilodalton peroxidase activity represents de novo protein synthesis. Both forms of peroxidase degraded chlorophyll in vitro, which is consistent with the hypothesis that peroxidases have catabolic or scavenging functions in senescent tissues.
Use of time resolution to eliminate bilirubin interference in the determination of fluorescein (1986)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTUse of time resolution to eliminate bilirubin interference in the determination of fluoresceinFrank V. Bright, George H. Vickers, and Gary M. HieftjeCite this: Anal. Chem. 1986, 58, 6, 1225–1227Publication Date (Print):May 1, 1986Publication History Published online1 May 2002Published inissue 1 May 1986https://pubs.acs.org/doi/10.1021/ac00297a056https://doi.org/10.1021/ac00297a056research-articleACS PublicationsRequest reuse permissionsArticle Views75Altmetric-Citations7LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Predictive Models of Insulin Resistance Derived from Simple Morphometric and Metabolic Measurements Related to Obesity in Baboons. (2008)

Abstract Non-human primates are valuable models for the study of insulin resistance and human obesity. In baboons, insulin sensitivity levels can be evaluated directly with the euglycemic clamp and is highly predicted by adiposity, metabolic markers of obesity and impaired glucose metabolism (i.e. percent body fat by DXA and hemoglobin A1C). However, a simple method to screen and identify obese insulin resistant baboons for inclusion in interventional studies is not available. We characterized a population of obese nondiabetic, insulin resistant baboons using the euglycemic clamp technique and used a multivariate linear regression analysis (after adjustment for gender) to test three different predictive models for insulin sensitivity. In the first model, abdominal circumference explained 63% of insulin mediated glucose uptake. The second model, which included fasting plasma insulin (log transformed) and abdominal circumference, explained 69% of insulin-stimulated glucose uptake. The third model, which contained abdominal circumference and 1/log (FPI+FPG), explained 70% of insulin sensitivity. In baboons, simple morphometric measurements of adiposity/obesity, i.e. abdominal circumference, plus baseline markers of glucose metabolism, i.e. fasting plasma glucose and insulin, provide a feasible method to screen and identify overweight/obese insulin resistant baboons for inclusion interventional studies aimed to study human obesity and type 2 diabetes.