gebhart/patrepeval huggingface dataset:
Crosslink point mobility in swollen polymer networks by phosphorus-31 spin-lattice relaxation in the rotating frame (1988)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCrosslink point mobility in swollen polymer networks by phosphorus-31 spin-lattice relaxation in the rotating frameL. Charles Dickinson, James C. W. Chien, and W. J. MacKnightCite this: Macromolecules 1988, 21, 10, 2959–2963Publication Date (Print):October 1, 1988Publication History Published online1 May 2002Published inissue 1 October 1988https://pubs.acs.org/doi/10.1021/ma00188a012https://doi.org/10.1021/ma00188a012research-articleACS PublicationsRequest reuse permissionsArticle Views71Altmetric-Citations7LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Evaluation of Bromovinyldeoxyuridine-Related Compounds in the Treatment of Experimental Herpes Simplex Keratitis (1985)

Several newly synthesized compounds, all structurally related to the highly potent and selective antiherpes agent bromovinyldeoxyuridine ( [E]-5-[2-bromovinyl]-2'-deoxyuridine), have been evaluated for their healing effect on herpes simplex virus type 1 keratitis in rabbits. These novel compounds included chloroethyldeoxyuridine (5-[2-chloroethyl]-2'-deoxyuridine), trifluoropropenyldeoxyuridine ( [E]-5-[3,3,3-trifluoro-1-propenyl]-2'-deoxyuridine), bromovinylaminodideoxyuridine ( [E]-5-[2-bromovinyl]-3'-amino-2',3'-dideoxyuridine), bromovinylarabinofuranosyluracil ( [E]-5-[2-bromovinyl]-1-beta-D-arabinofuranosyluracil), and glycylbromovinyldeoxyuridine (5'-O-aminoacetyl-[E]-5-[2-bromovinyl]-2'-deoxyuridine). Bromovinylaminodideoxyuridine and trifluoropropenyldeoxyuridine did not promote a significant healing of herpes simplex keratitis. Bromovinylarabinofuranosyluracil markedly reduced the severity of keratitis, but to a significantly lesser extent than bromovinyldeoxyuridine. Finally, chloroethyldeoxyuridine and glycylbromovinyldeoxyuridine caused a pronounced healing effect on herpes simplex keratitis, comparable to that obtained with bromovinyldeoxyuridine. Chloroethyldeoxyuridine was even slightly better than bromovinyldeoxyuridine, but the difference in their healing effect was not statistically significant.
Enhanced water stability and CO<sub>2</sub> gas sorption properties of a methyl functionalized titanium metal–organic framework (2014)

A methyl-modified metal–organic framework (m-TiBDC) exhibiting significantly enhanced hydrostability than unmodified TiBDC maintains its framework structure and also CO<sub>2</sub> gas adsorption capacity even after its immersion in water for 2 hours.
Effect of the Acoustic Reflex on the Impedance at the Eardrum (1965)

Seventeen ears of 12 subjects with normal hearing were tested in both a laboratory and a clinical setting to study impedance changes in normal human ears associated with the acoustic reflex. Compliance and resistance at the eardrum were measured with middle ear muscles relaxed and contracted by means of a contralateral noise stimulus, respectively. The reflex induced impedance changes were compared to similar impedance data obtained by other investigators, and to typical otosclerotic impedance values. The reflex is shown to affect the impedance by a decrease in compliance and a slight decrease in resistance.
Elevated Second-Trimester Serum Homocyst(e)ine Levels and Subsequent Risk of Preeclampsia (1999)

Our findings are consistent with other indications of vascular endothelial dysfunction predating clinical preeclampsia. Studies designed to examine the effect of dietary and/or pharmacological mediators of homocyst(e)ine metabolism in preeclampsia are warranted.
Spherical grating monochromator with interferometer control and in-vacuum reference (2002)

Physical Science Laboratory’s new generation of spherical grating monochromators incorporates a laser interferometer to control scan angle and an in-vacuum absolute angle reference, as well as other improvements. The design accommodates up to six gratings which can be moved axially (under motor control, with encoder position readback) at any scan angle. The gratings are cooled by means of spring-loaded clamps which conduct heat to a water-cooled plate. The instruments feature hollow roller bearings on the scan axis to minimize bearing runout, and a pseudosine-bar drive for precise control of grating angle. The interferometer angle-measuring optics are mounted inside the vacuum chamber and measure the angle between the grating scan axis and the instrument’s granite base. The laser interferometer measures the grating angle with a resolution of approximately 0.02 arcsec over the entire scan range of 40°. To provide a reference for the interferometer angle measurement, we have built an in-vacuum optical reference which uses custom chrome-on-glass reticles mounted inside the vacuum chamber. Collimated light from a source outside the vacuum passes through the reticles to yield quadrature signals which precisely define an absolute reference angle for the interferometer. Repeatability of the grating angle is within a range of ±0.05 arcsec. Two of these instruments are in operation at SRRC (Taiwan) and a third instrument has been delivered to NSLS (Brookhaven).
Teratological Nymphal<i>Ixodes scapularis</i>(Acari: Ixodidae) From Wisconsin (2015)

Abnormalities of physiological development (teratological forms) in ticks are rare. The occurrence of gigantism, dwarfism, gynandromorphs, missing legs, extra legs, and asymmetries is most often reported from lab-reared specimens, but has been observed in field-collected specimens. All morphologically anomalous ticks (besides gynandromorphy) described to date are from species other than Ixodes scapularis Say (Acari: Ixodidae). Here we describe four teratological I. scapularis nymphs collected while dragging vegetation in Wisconsin in 2015, including two asymmetrical ticks, one with a missing leg, and one with an extra leg.
Decontamination Efficacy and Skin Toxicity of Two Decontaminants against Bacillus anthracis (2015)

Decontamination of bacterial endospores such as Bacillus anthracis has traditionally required the use of harsh or caustic chemicals. The aim of this study was to evaluate the efficacy of a chlorine dioxide decontaminant in killing Bacillus anthracis spores in solution and on a human skin simulant (porcine cadaver skin), compared to that of commonly used sodium hypochlorite or soapy water decontamination procedures. In addition, the relative toxicities of these decontaminants were compared in human skin keratinocyte primary cultures. The chlorine dioxide decontaminant was similarly effective to sodium hypochlorite in reducing spore numbers of Bacillus anthracis Ames in liquid suspension after a 10 minute exposure. After five minutes, the chlorine dioxide product was significantly more efficacious. Decontamination of isolated swine skin contaminated with Bacillus anthracis Sterne with the chlorine dioxide product resulted in no viable spores sampled. The toxicity of the chlorine dioxide decontaminant was up to two orders of magnitude less than that of sodium hypochlorite in human skin keratinocyte cultures. In summary, the chlorine dioxide based decontaminant efficiently killed Bacillus anthracis spores in liquid suspension, as well as on isolated swine skin, and was less toxic than sodium hypochlorite in cultures of human skin keratinocytes.
<i>Ab initio</i>structure determination of sulfathiazole polymorph V from synchrotron X-ray powder diffraction data (1999)

The crystal structure of sulfathiazole [4-amino- N -(2,3-dihydro-2-thiazolylidene)benzenesulfonamide, C 9 H 9 N 3 O 2 S] polymorphic form V has been determined from high-resolution synchrotron X-ray powder diffraction data. The structure is monoclinic, space group P 2 1 / n , Z = 8, with two molecules in the asymmetric unit. The unit-cell dimensions are a = 14.3296 (3), b = 15.2733 (2), c = 10.4428 (2) Å and β = 91.052 (1)° with cell volume V = 2285.13 (8) Å 3 . The structure has been solved by direct methods without recourse to any computational modelling techniques for generating possible structures. The unrefined structure obtained from direct methods gave an R wp value of 36.5%. Refinement of atomic and displacement parameters yielded a final R wp of 12.54% ( R p = 9.37%). The conformations of the two molecules in the asymmetric unit are nearly identical and very similar to that found in other forms of sulfathiazole. The molecular packing is characterized by molecular sheets lying perpendicular to the a axis. Each sheet is two molecules thick, being integrated by hydrogen bonding. With 16 non-H atoms in the molecule and two molecules in the asymmetric unit, this structure represents a further advance in terms of the complexity of an organic structure solved from X-ray powder diffraction data.
XFEM formulation for discontinuities in fractured rock masses (2015)

The paper describes some aspects of the application of XFEM to represent Geomechanical discontinuities, including the choice of additional nodal variables and the appearance and remedies to the oscillations that may take place depending on the mesh layout. An example of application to recover the stresses along a discontinuity line emanating from a tunnel cross-section is presented together with the comparison to an analytical solution. The formulation is developed in terms of the “overhang” displacement variables on the other side of the discontinuity (instead of more traditional displacement jump variables), and the oscillations associated to nodes too close to the discontinuity are solved by moving those nodes onto the discontinuity (instead of moving them away as seems more common in current practice).
Dilithium tetraborate (Li/sub 2/B/sub 4/O/sub 7/) fabrication technology (2003)

Dilithium tetraborate (DLTB) is a piezoelectric material for frequency control and signal processing applications. The growth and fabrication technology of DLTB crystals are discussed, together with recent worldwide efforts to grow large bulk crystals and thin films. Special emphasis is given to: (1) the Czochralski technique, including the effort to eliminate a number of crystal defects arising from the use of this method and the activity for the growth of large diameter crystal boules: and (2) the sol-gel method for thin film preparation, including the effect of acid and water on crystallization and side products. Other lesser-used techniques for bulk and thin film production of DLTB, such as Bridgman growth, RF sputtering, vapor deposition, and laser ablation deposition, are discussed.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Multiplex analysis of age‐related protein and lipid modifications in human Bruch's membrane (2010)

ABSTRACT Aging of the human retina is characterized by progressive pathology, which can lead to vision loss. This progression is believed to involve reactive metabolic intermediates reacting with constituents of Bruch's membrane, significantly altering its physio‐chemical nature and function. We aimed to replace a myriad of techniques following these changes with one, Raman spectroscopy. We used multiplexed Raman spectroscopy to analyze the age‐related changes in 7 proteins, 3 lipids, and 8 advanced glycation/lipoxidation endproducts (AGEs/ALEs) in 63 postmortem human donors. We provided an important database for Raman spectra from a broad range of AGEs and ALEs, each with a characteristic fingerprint. Many of these adducts were shown for the first time in human Bruch's membrane and are significantly associated with aging. The study also introduced the previously unreported up‐regulation of heme during aging of Bruch's membrane, which is associated with AGE/ALE formation. Selection of donors ranged from ages 32 to 92 yr. We demonstrated that Raman spectroscopy can identify and quantify age‐related changes in a single nondestructive measurement, with potential to measure age‐related changes in vivo. We present the first directly recorded evidence of the key role of heme in AGE/ALE formation.—Beattie, J. R., Pawlak, A. M., Boulton, M. E., Zhang, J., Monnier, V. M., McGarvey, J. J., Stitt, A. W. Multiplex analysis of age‐related protein and lipid modifications in human Bruch's membrane. FASEB J. 24, 4816–4824 (2010). www.fasebj.org
Case of a Superficial Hypopharyngeal Cancer at the Pharyngoesophageal Junction Which Is Detected by Transnasal Endoscopy Using Trumpet Maneuver (2015)

Aims: In order to observe the pharyngoesophageal junction, the trumpet maneuver with trans-nasal endoscopy was used. Its efficacy is reported here. Material and Methods: A 71-year-old man who underwent esophagectomy in esophageal cancer 2 years ago was admitted to our hospital with primary pharyngeal cancer. The type of upper endoscope used was EG-580NW (FUJI Film, Tokyo, Japan). The endoscope is a trans-nasal endoscope that can provide high quality endoscopic images. The pharyngeal cancer located at right lateral wall which was previously detected could be observed easily. We asked the patient to blow hard and puff his cheeks with his mouth closed. When inspecting the hypopharynx and the orifice of the esophagus, we told the patient that we would start the trumpet maneuver. Results: After the trumpet maneuver, the pharyngeal mucosa was stretched out. Another primary lesion was observed at the posterior wall of the hypopharynx near the pharyngoesophageal junction. This technique provided a much better view of the lesion than had been possible with trans-oral endoscopy，allowing us to remove the biopsy specimen without sedation. Conclusion: In conclusion, the trumpet maneuver using trans-nasal endoscopy is a useful technique for precise inspection before treatments for patients who have already detected the lesions.
Olmesartan for the Treatment of Arterial Hypertension (2008)

Angiotensin-receptor blockers (ARBs) are an important class of agents used for the treatment of arterial hypertension. Olmesartan medoxomil, the seventh latest ARB approved by the US FDA, is an oral, once-daily, AT(1)-receptor selective ARB with high receptor affinity. Pharmacologically, it acts as a competitive and insurmountable Ang II antagonist with linear pharmacokinetics and without cytochrome P450 interaction. The drug is licensed for the treatment of arterial hypertension alone or in combination with other antihypertensive agents. Olmesartan has demonstrated its dose-dependent inhibitory effect on Ang I-induced blood pressure responses between 10 and 80 mg in Phase II studies. These results, confirmed in an international clinical trial programme covering over 3000 hypertensive patients in numerous studies, demonstrated rapid blood pressure-lowering effects within 1 week. A daily oral dose of 20 mg olmesartan is considered to be the optimal dose. In clinical trials and postmarketing studies, olmesartan has been shown to be safe and well tolerated with an adverse event profile similar to the placebo. Active comparative studies demonstrated either similar or superior efficacy of olmesartan compared with other ARBs, angiotensin-converting enzymes inhibitors, beta-blockers or calcium-channel blockers. Besides its antihypertensive efficacy, olmesartan was shown in clinical trials to reduce vascular microinflammation, decrease intrarenal vascular resistance, significantly reduce vascular remodeling of small resistance arteries and exert antiatherosclerotic effects by significantly reducing the volume of large atherosclerotic plaques.
Electrostatic Interaction between ATP and Lysenin Channels Modulates the Conductance (2015)

This work focuses on understanding the interactions between lysenin, a pore-forming toxin, and ATP. We measured the conductance of lysenin channels inserted into a planar, lipid bilayer membrane. The channel conductance before and after the addition of ATP was determined from the slope of current versus voltage plots. Single-channel and buffer-exchange experiments were used to assess reversibility and to study the interaction mechanism. Our results show ATP blocks current through the channels in a concentration dependent manner and induces a significant shift in the voltage required to close the channels. Single channel current measurements indicate the absence of step-wise changes, which suggests ATP binds electrostatically to lysenin and in doing so partially occludes the channels. This hypothesis is further supported by observed reversibility of ATP binding when employing buffer exchange. The interaction between ATP and lysenin channels induces a decrease in current and shifts the open probability curve upward. The most probable interaction mechanism is electrostatic binding, which may yield partial occlusion of the channels and affect the voltage-gating energy landscape.
An approach to information propagation in 1-D cellular neural networks-Part I: Local diffusion (1998)

This is the first of two companion papers devoted to a deep analysis of the dynamics of information propagation in the simplest nontrivial Cellular Neural Network (CNN), which is one-dimensional and has connections between nearest neighbors only. We will show that two behaviors are possible: local diffusion of information between neighboring cells and global propagation through the entire array. This paper deals with local diffusion, of which we will first give an accurate definition, before computing the template parameters for which the CNN has this behavior. Next we will compute the number of stable equilibria, before examining the convergence of any trajectory toward them, for three different kinds of boundary conditions: fixed Dirichlet, reflective, and periodic.
A Note on Two Dimensional Division Ring Extensions (1989)

A division subring Γ of a division ring Δ is said to be Galois in Δ (and Δ is Galois over Γ) if Γ is the set of invariants (or fixed points) of a group of automorphisms acting in Δ. The two dimensional Galois extensions of a division ring have been determined by Dieudonné.2 In this note we shall show that if Γ is a division ring of characteristic ≠ 2 which is finite dimensional over its center Ψ and Δ contains Γ and has left dimensionality [Δ:Γ] L = 2 then Δ is Galois over Γ On the other hand, we shall construct a class of examples where [Δ: Γ] L = 2 = [Δ:Γ] R , Γ of characteristic ≠ 2 and Δ is not Galois over Γ.
Modeling of NOx Emissions with Comparison to Exhaust Measurements for a Gas Fuel Converted Heavy-Duty Diesel Engine (1996)

<div class="htmlview paragraph">In previous work the KIVA-II code has been modified to model modem DI diesel engines and their emissions of particulate soot and oxides of nitrogen (NOx). This work presents results from a program to further validate the NOx emissions models against engine experiments with a well characterized modern engine. To facilitate a simplified comparison with experiments, a single cylinder research version of the Caterpillar 3406 heavy duty DI diesel engine was retrofitted to run as a naturally-aspirated, propane-fueled, spark-ignited engine. The retrofit includes installing a low compression ratio piston with bowl, adding a gas mixer, replacing the fuel injector assembly with a spark plug assembly and adding spark and fuel stoichiometry control hardware. Cylinder pressure and engine-out NOx emissions were measured for a range of speeds, exhaust gas residual (EGR) fractions, and spark timing settings.</div> <div class="htmlview paragraph">Cylinder pressure and engine-out NOx emissions results predicted with the modified version of KIVA were found to compare favorably with the engine measurements. Good agreement was found for both cylinder pressure and NOx emissions for the range of speeds, spark timings and EGR fractions of the engine experiments. Furthermore, the Extended Zel'dovich NO Mechanism was found to satisfactorily model the measured engine-out NOx emissions over the full range of conditions. The present results demonstrate that multidimensional modeling is useful for NOx emissions predictions in large bore spark ignition engines.</div>
Metabolism of human embryos following cryopreservation: Implications for the safety and selection of embryos for transfer in clinical IVF (2006)

The data suggests that cryopreservation in IVF is a safe procedure and that amino acid turnover can be used to select which cryopreserved embryo will develop to the blastocyst stage, irrespective of their post-thaw grade.
Prognostic significance of Ki-67 immunostaining in nonmetastatic renal cell carcinoma. (1993)

The tumor-specific PR obtained by Ki-67 labeling seems to be an independent marker to describe the proliferative activity and aggressiveness of individual tumors. This new tumor-biologic marker detects RCC patients at high risk for recurrent disease, especially in those cases with identical pT and G.
Effect of the similarity of gut microbiota composition between donor and recipient on graft function after living donor kidney transplantation (2020)

Graft outcomes of unrelated donor kidney transplant are comparable with those of related donor kidney transplant despite their genetic distance. This study aimed to identify whether the similarity of donor-recipient gut microbiota composition affects early transplant outcomes. Stool samples from 67 pairs of kidney transplant recipients and donors were collected. Gut microbiota differences between donors and recipients were determined using weighted UniFrac distance. Among the donor-recipient pairs, 30 (44.8%) pairs were related, while 37 (55.2%) were unrelated. The unrelated pairs, especially spousal pairs, had similar microbial composition, and they more frequently shared their meals than related pairs did. The weighted UniFrac distance showed an inverse correlation with the 6-month allograft function (p = 0.034); the correlation was significant in the unrelated pairs (p = 0.003). In the unrelated pairs, the microbial distance showed an excellent accuracy in predicting the estimated glomerular filtration rate of < 60 mL/min/1.73 m<sup>2</sup> at 6-months post-transplantation and was better than human leukocyte antigen incompatibility and rejection. The incidence of infection within 6 months post-transplantation increased in the recipients having dissimilar microbiota with donors compared to the other recipients. Thus, pre-transplantation microbial similarity in unrelated donors and recipients may be associated with 6-month allograft function.
ChemInform Abstract: AN ELECTRON SPIN RESONANCE STUDY OF THE HYDROLYTIC PRODUCTS FORMED BY TITANIUM(III) TRICHLORIDE IN AQUEOUS AND MIXED AQUEOUS SOLUTIONS AND FROZEN SOLUTIONS (1975)

Abstract Durch ESR‐Messungen von wäßrigen TiCl 3 enthaltenden Lösungen bei Zimmertemperatur und 77K werden als Hydrolyse‐Hauptprodukt bei niedrigem pH‐Wert aquotisierte Ti(OH)( 2 +) ‐ Spezies neben geringen Mengen dimerer Ti 2 (OH) 2 ( 4 +)‐Ionen nachgewiesen.