gebhart/patrepeval huggingface dataset:
Ultrasonic Examination of Double-Shell Tank 241-AY-101 Examination Completed August 2003 (2003)

COGEMA Engineering Corporation (COGEMA), under a contract from CH2M Hill Hanford Group (CH2M Hill), has performed an ultrasonic nondestructive examination of selected portions of Double-Shell Tank 241-AY-101. The purpose of this examination was to provide information that could be used to evaluate the integrity of the wall of the secondary tank. The requirements for the ultrasonic examination of Tank 241-AY-101 were to detect, characterize (identify, size, and locate), and record measurements made of any wall thinning or pitting that might be present in the wall of the secondary tank. Any measurements that exceed the requirements set forth in the Engineering Task Plan (ETP), RPP-11832 (Jensen 2002) and summarized on page 1 of this document, are reported to CH2M Hill and the Pacific Northwest National Laboratory (PNNL) for further evaluation. Under the contract with CH2M Hill, all data is to be recorded on disk and paper copies of all measurements are provided to PNNL for third-party evaluation. PNNL is responsible for preparing a report that describes the results of the COGEMA ultrasonic examinations.
Seven-Year Clinical and Immune Monitoring Follow-Up in an Alemtuzumab and Sirolimus Regimen for Kidney Transplantation. (2014)

PURPOSE: To characterize immunologic conditions allowing for successful tapering of sirolimus monotherapy after alemtuzumab induction. METHODS: Ten patients underwent renal transplantation (9 HLA haplo-matched; 1 zero mismatch)(ITN013ST). Immunosuppression included Campath-1H (3 doses of 30mg), short-term Tacrolimus (60 days), and eventual Sirolimus monotherapy. Immune monitoring included measurement of donor specific antibody (DSA), regulation via the indirect pathway using the tv-DTH assay, and cytokine kinetics (MLC). Sirolimus dose was tapered at 1-year if patient GFR was greater than 50 mL/min/1.73m2 and no rejection was present on protocol biopsy. RESULTS: All patients are alive 7 years post transplant with their original renal allografts. Patients were grouped for comparison: (1) Low dose monotherapy Sirolimus (4-5 ng/ml serum level), (2) standard dose monotherapy Sirolimus (7-8ng/ml), and (3) traditional triple-drug immunosuppression. Group 1 patients (n=3) were rejection free with good GFR (61-68 mL/min/1.73m2), regulators, hypo or non-responsive to donor via MLC assay, with no DSA development. Group 2 patients (n=3) were rejection free with adequate GFR (48-54 mL/min/1.73m2). One patient was a non-regulator and the other two inconsistently regulated, all were hypo-responsive by MLC assay, and one patient developed class-I DSA. Group 3 patients (n=4) all developed acute rejection (2 AMR; 2 AMR+ACR) with poor GFR (11-39 mL/min/1.73m2). There were 2 non-regulators, 1 inconsistent regulator, and 1 sensitized patient. Two patients in Group 3 were hyper-responsive via MLC and three patients developed DSA (1 Class-I; 2 Class I+II).Figure: No Caption available.CONCLUSION: Patients who maintain excellent renal function on low dose sirolimus monotherapy demonstrated consistent indirect pathway regulation post transplant. Patients with no early regulation, an inconsistent indirect pathway status, or consistent sensitization, required more standard immunosuppression.
The relationship between osteoporosis and periodontitis in women aged 45–70 years (2011)

Subjects with osteoporosis (OPR) presented with greater CAL than the subjects with normal BMDa, which suggests a greater severity of periodontitis. Subjects with OPR had greater GR than the subjects with normal BMDa. Subjects with osteopenia and subjects with normal BMDa did not differ in CAL, which might suggest that the early diagnosis of reduced BMDa, prior to the establishment of a significant negative impact on the periodontal tissues, might be important. Smoking and menopausal status did not alter these associations.
Black teeth: beauty or caries prevention? Practice and beliefs of the Kammu people (2006)

The procedure was simple and resulted in black, beautiful (?) teeth. The soot of DD nuts effectively inhibited growth of salivary mutans streptococci in in vitro experiments.
Heterogeneous Functional Integration and Manufacturing at the Nanoscale (2009)

Nanoscience – the ‘science of the small’ – produces stunning revelations that, almost daily, redefine the realm of the possible. Yet, the manufacturing processes and systems to transform this new knowledge into technologies and products that benefit us in our daily life is a crucial missing element. At Illinois, the Nanoscale Chemical-Electrical-Mechanical Manufacturing Systems (Nano-CEMMS) Center, a NSF-sponsored Nanoscale Science and Engineering Center (NSEC), is exploring and developing new methodologies and tools that exploit chemical, mechanical, and electronic phenomena and processes for manufacturing at the nanoscale. This talk is a broad overview of the research within the Center. Specifically, it will describe heterogeneous integration in product design as a motivation for a repertoire of micro and nanoscale manufacturing processes. Processes such as electrohydrodynamic printing, electrochemical patterning, micro transfer printing, etc. will be described. The possibilities for patterning and integrating mechanical, optical and mechanical functions into materials will be discussed.
Coral reef habitat discrimination using multivariate spectral analysis and satellite remote sensing (2003)

Coral reefs are important both biologically and economically, but are under increasing pressure from pollution and human-induced disturbance. Coral reefs are often remote, relatively large and shallow. Thus, optical remote sensing techniques provide an efficient and cost-effective approach to mapping and monitoring the condition of reefs. We tested the hypothesis that in-situ spectral signatures, together with water column attenuation measurements, satellite imagery and Geographical Information System, can effectively differentiate reef substrates. In situ upwelling radiances were collected for coarse descriptive habitat types near Lee Stocking Island, Bahamas between 17 July and 27 July, 1998. Down-looking spectral scans from 300-750 nm were taken 1 m above the substrate and 1 m below the water surface, using a LiCor-1800 underwater spectroradiometer. Principal component analysis of upwelling radiances indicated that wavelengths from 515-580 nm are most useful in distinguishing between substrates. Landsat Thematic Mapper (TM) multi-spectral imagery was geo-registered and an ISODATA unsupervised classification was used to delineate reef features and associated communities. Using this method, we achieved an overall accuracy of 74% for coarse descriptive resolution mapping of seven substrate types (i.e. ocean, deep sand, shallow sand, deep coral, shallow coral, seagrass, and mixed sand and seagrass) within an area of 590 km 2 near Lee Stocking Island.
Characterization of a Novel Fungal Protein, p15, Which Induces Neuronal Differentiation of PC12 Cells (1999)

In our previous paper, we reported that a 15 kDa protein (p15) produced by a fungus, genus Helicosporium, enhanced NGF-induced neurite outgrowth from PC12 cells. Here we further characterized the actions of p15. The complete amino acid sequence of p15 was determined and it was shown to be a hydrophilic protein composed of 118 amino acid residues with two intramolecular disulfide bridges. p15-induced neurite outgrowth was blocked by the depletion of extracellular Ca(2+) in the culture medium and was significantly inhibited by L-type Ca(2+) channel inhibitor nicardipine. p15 stimulated Src kinase and MAPK activities, and neurite outgrowth was not observed in srcDN2, a dominant negative c-src(K295R)-expressing cell line, and was significantly reduced in RasN17-expressing cells. These results suggest that p15 stimulates neurite outgrowth through the potentiation of L-type Ca(2+) channels, thereby activating the Src-Ras-MAPK cascade.
Solution-Like Behavior of Photoswitchable Spiropyrans Embedded in Metal–Organic Frameworks (2017)

1,3,3-Trimethylindolino-6'-nitrobenzopyrylospiran (SP-1) as an example of a photoswitchable spiropyran was loaded into the pores of different prototypical metal-organic frameworks, namely MOF-5, MIL-68(In), and MIL-68(Ga), by a vapor-phase process. The successful incorporation in the pores of the MOF was proven by X-ray powder diffraction, and the amount of the embedded photoswitchable guest was determined by X-ray photoelectron spectroscopy and elemental analysis. In contrast to the sterically hindered crystalline state, SP-1 embedded in solid MOF hosts shows photoswitching under irradiation with UV light from the spiropyran to its merocyanine form with a nearly complete photoisomerization. Switching can be reversed by heat treatment. These switching properties were confirmed by means of UV/vis and IR spectroscopy. Remarkably, the embedded guest molecules show photoswitching and absorption properties similar to those in the dissolved state, so that MOFs might be considered as "solid solvents" for photoswitchable spiropyrans. In contrast to that, embedment of SP-1 in the smaller pores of MIL-53(Al) was not successful. SP-1 is mainly adsorbed on the surfaces of the MIL-53(Al) particles, which also leads to photoswitching properties.
DIABETOGENIC ACTION OF HUMAN GROWTH HORMONE Synthesis and Activity of<i>C</i>‐terminal Fragments (1979)

Three peptides corresponding to the C-terminal region of human growth hormone have been synthesized by the solid-phase method: HGH-(177--191), HGH-(178--191) and HGH-(179--191). The diabetogenic activities of these synthetic peptides are reported. The data indicate that extension of HGH-(179--191) at its NH2-terminus is required for in vivo activity. The reduced and S-carbamidomethylated form of HGH-(177--191) was also active, indicating that the disulphide bond is possibly not a prerequisite for biological activity.
Cleavage of aldehyde hydrazonium iodides under mild conditions. A convenient route to chiral nitriles of high enantiomeric purity (1990)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCleavage of aldehyde hydrazonium iodides under mild conditions. A convenient route to chiral nitriles of high enantiomeric purityJ. S. Moore and S. I. StuppCite this: J. Org. Chem. 1990, 55, 10, 3374–3377Publication Date (Print):May 1, 1990Publication History Published online1 May 2002Published inissue 1 May 1990https://pubs.acs.org/doi/10.1021/jo00297a072https://doi.org/10.1021/jo00297a072research-articleACS PublicationsRequest reuse permissionsArticle Views250Altmetric-Citations22LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Evaluating the impact of simultaneous multithreading on network servers using real hardware (2005)

This paper examines the performance of simultaneous multithreading (SMT) for network servers using actual hardware, multiple network server applications, and several workloads. Using three versions of the Intel Xeon processor with Hyper-Threading, we perform macroscopic analysis as well as microarchitectural measurements to understand the origins of the performance bottlenecks for SMT processors in these environments. The results of our evaluation suggest that the current SMT support in the Xeon is application and workload sensitive, and may not yield significant benefits for network servers.In general, we find that enabling SMT on real hardware usually produces only slight performance gains, and can sometimes lead to performance loss. In the uniprocessor case, previous studies appear to have neglected the OS overhead in switching from a uniprocessor kernel to an SMT-enabled kernel. The performance loss associated with such support is comparable to the gains provided by SMT. In the 2-way multiprocessor case, the higher number of memory references from SMT often causes the memory system to become the bottleneck, offsetting any processor utilization gains. This effect is compounded by the growing gap between processor speeds and memory latency. In trying to understand the large gains shown by simulation studies, we find that while the general trends for microarchitectural behavior agree with real hardware, differences in sizing assumptions and performance models yield much more optimistic benefits for SMT than we observe.
Expanding the Cavity Size: Preparation of 2:1 Inclusion Complexes Based on Dinuclear Square Metallocycles (2009)

The self-assembly of two new ligands based on the trans-1,2-bis(4-pyridyl)ethylene motif with palladium or platinum complexes led to quadrangular metallocycles. 1,1'-Methylenebis(4-((E)-2-(pyridin-4-yl)vinyl)pyridinium gave the square metallocycles, while the second ligand, which is less symmetrical, gave a mixture of the regioisomeric metallocyles. The metallocycles display the ideal disposition of the pi-acceptor units to maximize the pi-stacking interactions with aromatic guests. Thus, molecular recognition of pi-donor aromatic guests by square metallocycles produced the corresponding 2:1 inclusion complexes. On the other hand, starting from the mixture of regioisomers, the incorrect regioisomer rearranged to the correct metallocycle upon the addition of aromatic guests. On the basis of this behavior, a [3]catenane was obtained regioselectively from the mixture of the regioisomeric metallocycles and the appropriate cyclophane. The formation of this catenane was confirmed by NMR and X-ray crystallographic studies.
D134 Effects of oxygen concentration on the radiative characteristics of NH_3/N_2/O_2 laminar premixed flame (2015)

The total radiative heat flux and the radiation spectra of the ammonia flame were measured to understand the radiative characteristics of ammonia flame in this study. A slot burner was used for stabilizing the laminar ammonia/N_2/O_2 premixed flame. The concentration of O_2 in the oxidizer and equivalence ratio were varied for increasing the flame temperature. The results showed that radiative heat flux of ammonia was lower than that of methane/air premixed flame in all condition of that has the same net heating values per unit time.
Roles of vascular endothelium in atherogenesis. (1995)

One of the characteristic features of early atherogenesis is focal accumulation of monocyte/macrophages and T lymphocytes in arteral intima. Endothelial expression of adhesion molecules, such as VCAM-1 and ICAM-1, appear to play a role in this process. Lysophosphatidylcholine (lyso-PC), a prominent phospholipid component of atherogenic lipoproteins such as oxidized LDL and β-VLDL, can upregulate expression of VCAM-1 and ICAM-1 in cultured human and rabbit arterial endothelial cells. Lyso-PC also induces endothelial expression of potent smooth muscle growth factors such as PDGF A- and B-chains and HB-EGF in culture.Thus, lyso-PC may be an important stimulus, in atherogenesis, to enhance mononuclear leukocyte recruitment into arterial lesions and to stimulate migration and proliferation of vascular smooth muscle cells in situ.
Effect of Previous Live Birth and Prior Route of Delivery on the Outcome of Early Medical Abortion (2009)

Parous women are at increased risk for failed medical abortion in comparison with nulliparous women. Prior cesarean delivery is significantly associated with failed medical abortion.
Effects of building design and quality on nuisance bird problems (1976)

G nerve agents are colorless, odorless, and lethal chemical warfare agents (CWAs). The threat of CWAs, which cause critical damage to humans, continues to exist, e.g., in warfare or terrorist attacks. Therefore, it is important to be able to detect these agents rapidly and with a high degree of sensitivity. In this study, a surface acoustic wave (SAW) array device with three SAW sensors coated with different sensing materials and one uncoated sensor was tested to determine the most suitable material for the detection of nerve agents and related simulants. The three materials used were polyhedral oligomeric silsesquioxane (POSS), 1-benzyl-3-phenylthiourea (TU-1), and 1-ethyl-3-(4-fluorobenzyl) thiourea (TU-2). The SAW sensor coated with the POSS-based polymer showed the highest sensitivity and the fastest response time at concentrations below the median lethal concentration (LCt<sub>50</sub>) for tabun (GA) and sarin (GB). Also, it maintained good performance over the 180 days of exposure tests for dimethyl methylphosphonate (DMMP). A comparison of the sensitivities of analyte vapors also confirmed that the sensitivity for DMMP was similar to that for GB. Considering that DMMP is a simulant which physically and chemically resembles GB, the sensitivity to a real agent of the sensor coated with POSS could be predicted. Therefore, POSS, which has strong hydrogen bond acid properties and which showed similar reaction characteristics between the simulant and the nerve agent, can be considered a suitable material for nerve agent detection.
Thermo-structural behavior of underfilled flip-chips (2002)

The continuing drive towards high-density, low-profile integrated circuit packaging has accelerated the spread of flip-chip technology. The use of an area array of solder bumps for the electrical and mechanical, as well as thermal attachment of the chip to the substrate provides flip-chip technology with considerable advantages in cost, density, and electrical performance, relative to the use of conventional single-chip packages. Unfortunately, however the difference in the coefficients of thermal expansion, between the silicon die and the substrate, leads to substantial, thermally-induced strains, which can result in fatigue failure of the solder joints. This problem is exacerbated by the use of the larger chips now becoming available. In recent years it has been found possible to obtain dramatically-higher reliability and to operate successfully with much larger chip sizes by "underfilling" the gap between the chip and substrate with epoxy. The present effort is aimed at exploring the thermo-structural behavior of such underfilled chips and more firmly establishing the physical basis for the improved reliability of this packaging technology. The thermo-structural behavior of an underfilled flip-chip package has been evaluated using the structural FEM code NIKEDP and employing an axisymmetric model of a typical flip-chip structure. In the course of this effort, numerical simulations were performed for underfill materials of varying thermo-structural properties and two solder bump heights. The results were used to examine the parametric sensitivity of the thermal strain in the solder joints and the axial, as well as shear, stress in the underfill material. The Coffin-Manson relation is used to relate the increased number of cycles-to-failure to the solder strain reduction associated with the use of underfilling.
Growth and development of journalism in the United States (1899)

Citation: Wilson, Alexander George. Growth and development of journalism in the United States. Senior thesis, Kansas State Agricultural College, 1898.
Proton MR spectroscopy of gadolinium‐enhanced multiple sclerosis plaques (1992)

Magnetic resonance (MR) imaging and proton MR spectroscopy were performed in 14 patients with clinically definite multiple sclerosis (MS). Prominent resonances in the 0.5-2.0-ppm region were seen in the spectra of six of nine gadopentetate dimeglumine-enhanced plaques in seven patients. These resonances were presumed to originate in lipids and other myelin breakdown products. Similar resonances were detected in only seven of 21 unenhancing plaques. The more frequent presence of such signals in the gadolinium-enhanced regions indicates that myelin breakdown is often associated with the inflammation that occurs in early stages of MS plaque evolution. It remains uncertain, however, whether active inflammation as indicated by gadolinium enhancement is a necessary precursor of myelin breakdown as detected at MR spectroscopy. Quantitative spectral analysis did not indicate statistically significant differences in N-acetyl aspartate and choline levels relative to creatine plus phosphocreatine between healthy volunteers and MS patients.
Development and characterization of a pair of 30–40 ps x-ray framing cameras (1995)

We have constructed two slightly different high-speed framing cameras for use on NOVA and the OMEGA Upgrade. Both units are based on the gating of a microchannel plate, with one detector having a pore length to diameter ratio half that of the other. We will discuss the factors limiting the temporal resolution of each detector and will compare the results of modeling with gate width measurements taken using a short-pulse laser. We will also compare time-resolved x-ray images recorded using one of these devices with data from an older (∼90 ps resolution) detector.
Magnetic resonance imaging in primates. The example of the mouse lemur (Microcebus murinus): From detection of pathological aging to therapeutic evaluations (2010)

Cerebral aging is a major public health issue in our societies as the aged population increases dramatically. It leads in many cases to neurodegenerative diseases such as Alzheimer disease (AD). Rodents and particularly transgenic mice are widely used as models for research on physiopathology of cerebral aging, neurodegenerative diseases and for the evaluation of therapies. However these models do not mimic all the pathophysiological aspects of human diseases. Complementary models such as non-human primates are phylogenetically close to humans and thus more predictive of drug efficiency in humans. Mouse lemur (Microcebus murinus) is a small primate (about 12cm, 100g) described as a useful model of cerebral aging and as a potential model of AD. Indeed several animals develop age-associated cerebral alterations like amyloidosis and other cerebral changes. Non invasive medical imaging methods such as magnetic resonance imaging (MRI) can be used to follow-up brain changes in these animals. In this review, we present how mouse lemurs can be followed-up by MRI and how MRI can be used during therapeutic evaluations and other applications in this model. MR images can be used to follow-up cerebral anatomy in mouse lemurs. It allows for the description of age-associated atrophic processes, age-associated iron accumulation, and vascular anatomy (thanks to MR angiography). Cerebral glucose uptake can be studied in mouse lemurs with other in vivo imaging modalities such as positron emission tomography (PET). In this case, MRI can be used as a support for quantification of radioligand uptake in specific structures. Ex vivo MR imaging is another MR protocol that can be used to describe cerebral aging in lemurs. It provides high resolution 3D histological brain images and allows for studying exquisite anatomical details or microhemorrhages. Finally, MRI can be used to practice cerebral surgery in lemurs and determine coordinates for stereotactic injections. It can also be used during therapeutic interventions by selecting animals to be involved in therapeutic trials and also by following specific MR biomarkers. MRI is thus critical to better characterize cerebral aging in the mouse lemur and to better carry out longitudinal studies in this primate model.