gebhart/patrepeval huggingface dataset:
Sources of variability in normal CA 125 levels. (1993)

Two hundred eighty-eight serum specimens from 144 asymptomatic menopausal women were assayed two times each for CA 125. The specimens were randomly assigned to sixteen CA 125 kits. Our purpose was to quantitate the biological variability and the assay variability that occurs at low levels of this tumor marker. All of the subjects had CA 125 values less than 35 units/ml. The total error from all sources was about 13% of the observed values. These findings suggest that single, low CA 125 values are reliable indicators of a woman's true CA 125 value. Clinical trials of ovarian cancer screening that incorporate CA 125 measurements should evaluate the performance of this test at thresholds lower than the usual 35 units/ml.
Developmental Expression of the Genes Encoding Transforming Growth Factor Alpha and Its Receptor in the Hypothalamus of Female Rhesus Macaques (1994)

Studies in female rats have shown that transforming growth factor alpha (TGF alpha) stimulates release of luteinizing hormone-releasing hormone (LHRH), the neuropeptide controlling sexual maturation, and that expression of the TGF alpha gene in the hypothalamus increases during both the initiation of normal puberty and after hypothalamic lesions that induce sexual precocity. Since blockade of epidermal growth factor receptors (EGFR), which mediate TGF alpha actions, delayed the normal timing of puberty, it was postulated that TGF alpha/EGFR contributes to the neuroendocrine process that underlies the initiation of normal female puberty. The present study was undertaken to examine the hypothesis that hypothalamic expression of the TGF alpha gene and its receptor changes in relation to the stage of sexual development in nonhuman primates, and to determine whether these changes are accompanied by corresponding alterations in LHRH gene expression. DNA fragments complementary to the coding regions of the rhesus monkey TGF alpha, EGFR and LHRH genes were cloned by reverse transcription-polymerase chain reaction (RT-PCR), sequenced and used to prepare monkey-specific antisense RNA probes. A quantitative RT-PCR was developed in which the cloned sequences were utilized to prepare RNA standards for the quantitation of tissue mRNA levels. Both TGF alpha and EGFR mRNA levels in the medial basal hypothalamus and preoptic area of female monkeys were elevated during neonatal life (1 week to 6 months of age), when FSH secretion is also high, decreased during juvenile development (8-18 months of age), when secretion of both FSH and LH is low, and markedly increased during the expected time of puberty (30-36 months of age). No such changes were observed in either the cerebellum or the cerebral cortex, two brain regions irrelevant to neuroendocrine reproductive control. In contrast to the pronounced alterations in hypothalamic TGF alpha/EGFR gene expression observed during sexual development, LHRH mRNA levels did not vary significantly during this time. Hybridization histochemistry revealed the presence of both TGF alpha and EGFR mRNAs in cells scattered throughout the hypothalamus, but more predominantly in the median eminence, suprachiasmatic nuclei, optic chiasm and cells along the wall of the third ventricle. These results demonstrate that increases in TGF alpha and EGFR gene expression, specific to the neuroendocrine brain, occur during developmental phases in which gonadotropin output is also elevated--most noticeably at the time of puberty.(ABSTRACT TRUNCATED AT 400 WORDS)
Bone morphogenetic proteins in tissue engineering: the road from laboratory to clinic, part II (BMP delivery) (2008)

Bone morphogenetic proteins (BMPs) are cytokines with a strong effect on bone and cartilage growth and with important roles during embryonic patterning and early skeletal formation. BMPs have promising potential for clinical bone and cartilage repair, working as powerful bone-inducing components in diverse tissue-engineering products. Synthetic polymers, natural origin polymers, inorganic materials and composites may be used as carriers for the delivery of BMPs. Carriers range from nanoparticles to complex three-dimensional (3D) scaffolds, membranes for tissue-guided regeneration, biomimetic surfaces and smart thermosensitive hydrogels. Current clinical uses include spinal fusion, healing of long bone defects and craniofacial and periodontal applications, amongst others. BMP-2 and BMP-7 have recently received approval by the US Food and Drug Administration (FDA) for specific clinical cases, delivered in absorbable collagen sponges. Considering the expanding number of publications in the field of BMPs, there are prospects of a brilliant future in the field of regenerative medicine of bone and cartilage with the use of BMPs.
VALIDAÇÃO DA ESCALA "PERFIL DO ESTILO DE VIDA INDIVIDUAL" (2008)

O objetivo desta investigação foi analisar a validade de construto da escala “Perfi l do Estilo e Vida Individual” (PEVI).Participaram da amostra 1606 professores de Educação Física que atuam no magistério público estadual dos estados da região Sul do Brasil. Na análise estatística, utilizou-se a análise fatorial, com rotação varimax, e adotou-se o critério de Kaiser para determinar o número de fatores necessários do instrumento, o alfa de Cronbach para verificar a consistência interna da escala e a correlação de Spearman para avaliar o nível de associação entre as questões. Os testes estatísticos foram realizados nos pacotes estatísticos Statistica 7.0 e SPSS 11.0, sendo adotado o nível de signifi cância de 5%. Os resultados da análise fatorial, quando considerados os cinco fatores, apresentaram a mesma distribuição das questões contempladas na proposta originaldesta escala, sendo que o total da variância explicada do instrumento foi de 58,65%. Em relação a sua consistência interna, encontrou-se um coeficiente alfa de Cronbach de 0,78, considerado razoável para avaliação geral do instrumento. Quanto ao nível de associação entre as questões, apenas em quatro situações encontrou-se moderada correlação (rs entre 0,45 e 0,57). As evidências encontradas confirmam que o instrumento apresenta adequada consistência interna, que as questões estãoassociadas aos respectivos componentes, assim como abordam diferentes indicadores das dimensões investigadas. Assim, conclui-se que o PEVI apresenta medidas psicométricas confiáveis para avaliar o estilo de vida de pessoas que apresentam características semelhantes aos participantes deste estudo.
Virgil, <i>Georgics</i> iv. 228–30 (1955)

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Listeriosis (1989)

<i>LISTERIA monocytogenes</i>has been recognized as a human pathogen for more than 50 years; it causes illness mainly in pregnant women, newborns, elderly persons, and immunocompromised persons. The organism is found in multiple ecological sites and throughout the food chain, and anecdotal reports have linked human illness with the ingestion of foods contaminated with<i>Listeria</i>.<sup>1</sup>More recently, it has been shown to cause outbreaks of illness that were associated with commercial food products.<sup>2-5</sup>The Food and Drug Administration has recommended product recalls when<i>L monocytogenes</i>has been identified in commercial foods that are available for consumption without further cooking. Although recalls have generated widespread public concern, information about the magnitude of risk and the clinical presentations of disease has not been widely available to the medical community. This article reviews the history, microbiology, ecology, pathogenesis, epidemiology, and clinical spectrum of human illnesses caused by<i>L monocytogenes</i>and highlights
Simple and economical capacitive displacement system for UHV operation (1979)

A parallel plate capacitor was assembled as a displacement transducer for operation in an UHV environment. The capacitive displacement system was linear over a 2.5 mum range with a resolution of 0.051 mum. Components in the electric circuit were common laboratory instruments.
Pasteurized Milk and Colostrum Feeding Systems: Capturing the Benefits and Avoiding the Pitfalls (2011)

producers are faced with the challenge of raising healthy calves, while still paying close attention to rearing costs and profit. Factors that may be considered in selecting a liquid feeding program may include the number of calves fed, economics and cash flow, nutritional characteristics, calf performance targets, resource availability (e.g. consistent supply of non-saleable milk), infectious disease control concerns, and personal preferences. Feeding raw non-saleable milk represents one way to gain important economic and nutritional efficiencies, but this can introduce the risk of infectious diseases to dairy calves. The introduction of commercial on-farm pasteurization systems offers producers a method for reducing the risk of pathogen transmission and can be a viable economic strategy for feeding dairy calves. However, to be successful, producers must be committed to properly managing and monitoring a pasteurized non-saleable milk feeding program. This paper will discuss some of the benefits and limitations of feeding pasteurized non-saleable milk, describe commercially available on-farm pasteurization systems, describe the results of studies with feeding pasteurized non-saleable milk, and outline the important considerations needed to successfully adopt and implement a pasteurized non-saleable milk feeding program. The paper will also discuss special considerations and early research findings surrounding the heat-treatment of colostrum.
INTERNAL COMBUSTION ENGINES (1970)

THERMODYNAMICS OF INTERNAL COMBUSTION ENGINES AND THEIR CARBURETION SYTEM ARE PRESENTED. /RRI/
Regional ground temperature survey in the Taupo‐Reporoa depression (1965)

Abstract Ground temperatures at a depth of 1 metre have been measured at intervals of 1 mile along all the roads and tracks within the Taupo—Reporoa depression. The results, which show extensive areas where ground temperature is in excess of normal, are assisting in the interpretation of an electrical resistivity survey currently under way.
Comparison of the Cytokine Profile in Mesenchymal Stem Cells from Human Adipose, Umbilical Cord, and Placental Tissues (2021)

Human mesenchymal stem cells (MSCs) can be isolated from various tissues. However, the cytokine profile in different MSC types remains unclear. In this study, MSCs were extracted from adipose, umbilical cord, and placental tissues. The surface marker expression, multilineage differentiation potential, and cytokine secretion of these cells were compared. The isolated MSCs exhibited similar morphology and surface marker expression. However, they differed with regard to their differentiation potential. Adipose-MSCs (A-MSCs) exhibited a higher potential for adipogenesis and osteogenic differentiation compared with umbilical cord-MSCs (UC-MSCs) and placental-MSCs (P-MSCs). The expression levels of 80 cytokines were detected, and the data demonstrated that the three MSC types abundantly secreted insulin-like growth factor-binding protein (IGFBP)-4, IGFBP-3, tissue inhibitor of metalloproteinase (TIMP)-1, TIMP-2, IGFBP-6, monocyte chemoattractant protein-1, and granulocyte colony-stimulating factor. However, the expression levels of vascular endothelial growth factor, tumor necrosis factor alpha, interleukin (IL)-6 receptor, and IL-13 in A-MSCs were higher compared with those of UC-MSCs and P-MSCs. Moreover, the expression levels of intercellular adhesion molecule-1 and growth differentiation factor 15 were lower in A-MSCs. Kyoto Encyclopedia of Genes and Genomes analysis indicated that the "adipocytokine" and the "PI3K/Akt pathways" were enriched in A-MSCs. Taken together, the results demonstrated that MSCs from different sources exhibited differences in the secretion of specific factors. A-MSCs were associated with the expression of several proangiogenic factors and may be an improved source for angiogenesis and tissue regeneration.
Global Warming Problems and Solid Waste Management. Actions Towards Global Environmental Problems by Electric Power Co. Examples by Kansai Electric. (1997)

関西電力 (株) は, 地球環境保全を重要な経営課題の一つとして位置づけ, 具体的な行動計画である「関西電力地球環境アクションプラン」を策定し, 全事業分野において具体的な活動を着実に推進している。さらに, あらゆる企業活動においてCO2削減の可能性を追求するために, 総合的な対策として「ニューERA戦略」を展開している。「ERA」はEfficiency (エネルギー利用の効率化) , Reduction (電力生産におけるCO2排出量の削減) , Absorption (自然界の吸収源の拡大) の頭文字をとったものである。すなわち, 原子力の推進や火力発電所での熱効率の向上などにより化石燃料への依存度を下げるだけでなく, 省エネルギーをお客さまに呼びかけたり, 自然界の生物などを利用したCO2の吸収・固定化の研究を進めるなど, E, R, Aの三つの対策をバランスよく進めている。
Quantum Impurities in the Two-Dimensional Spin One-Half Heisenberg Antiferromagnet (2002)

The study of randomness in low-dimensional quantum antiferromagnets is at the forefront of research in the field of strongly correlated electron systems, yet there have been relatively few experimental model systems. Complementary neutron scattering and numerical experiments demonstrate that the spin-diluted Heisenberg antiferromagnet La2Cu1-z(Zn,Mg)(z)O4 is an excellent model material for square-lattice site percolation in the extreme quantum limit of spin one-half. Measurements of the ordered moment and spin correlations provide important quantitative information for tests of theories for this complex quantum-impurity problem.
A Multiple Model-Based Approach for Fault Diagnosis of Jet Engines (2012)

In this brief, a novel real-time fault detection and isolation (FDI) scheme that is based on the concept of multiple model is proposed for aircraft jet engines. A modular and a hierarchical architecture is developed which enables the detection and isolation of both single faults as well as multiple concurrent faults in the jet engine. The nonlinear dynamics of a dual spool jet engine is linearized and a set of linear models corresponding to various operating modes of the jet engine (namely healthy and different faulty modes) at each operating point is obtained. Using the multiple model approach the probabilities corresponding to each operating point of the jet engine are generated and the current operating mode of the system is detected based on evaluating the maximum probability criteria. It is shown that the proposed methodology is also robust to the failure of pressure and temperature sensors and extensive levels of noise outliers in the sensor measurements. Simulation results are presented that demonstrate the effectiveness and capabilities of our proposed multiple model FDI algorithm for both structural faults and an actuator fault in the aircraft jet engine.
Thermal stress cracking in granite (1989)

We have developed a comprehensive experimental capability to study thermally induced microfractures in rock. We count acoustic emissions and measure compressional wave velocities while a sample is heated to a maximum temperature of 300°C under confining pressures up to 55 MPa. After a heating cycle we measure crack porosity and crack compressibility. We count the cracks under an SEM, sorting them by grain boundary and intragranular types and by mineral pair occurrence. Our observations reveal that (1) significant thermal cracking occurs in granites heated above 200° or 250°C under 28 and 55 MPa and above 100°C in granites heated under 7 MPa, (2) most newly created thermal cracks close at pressures below 40 MPa (1.5 km depth), (3) grain boundaries between quartz grains or between quartz and another mineral are preferentially cracked, (4) the threshold temperature for acoustic emissions is a positive, linear function of pressure, (5) total acoustic emission counts in Westerly granite heated to 300°C are slightly lower under 55 than 28 MPa confining pressure and are substantially lower under 28 than 7 MPa, (6) the compressional velocity decreases 22% as Westerly granite is heated to 300°C at 7 MPa, 15% at 28 MPa, and 10% at 55 MPa, and (7) greater hysteresis in compressional velocities occurs in samples heated at lower pressures. The acoustic emission counts in Westerly granite during heating show one or more peaks of activity as a function of temperature, with more peaks at lower pressures. We interpret this result to mean that additional crack populations are able to open at lower confining pressures. The curves of acoustic emission count rates can be fit by summing one to three Gaussian density functions.
Development of a new high performance immunoaffinity micro-column for aflatoxin B_1 purification in crain and oil (2006)

A new micro-column combined with a semiautomatic negative-pressure apparatus for aflatoxin B_1 purification characterized by high performance,simplicity and convenience for use was developed from seven self-designed micro-columns based on immunoaffinity.The condition such as injection,rinse, elution,flow velocity,binding capability,recovery and stability of the columns were studied and optimized.The results showed that the binding capability of the column exceeded 25μg/kg,and the recoveries rate were from 80.00%~91.50% in different level.The RSD of different batches were 1.76% which indicated that different batches of columns had no significant differences.According to national standard method,the purifying of aflatoxin B_1 in grain and oil samples was carried out by the new self-designed columns,the recoveries were in range of 80.00%~92.00%.It was concluded that the new column could satisfy the request of national standards for aflatoxin B_1 determination in grain and oil.
Novel two-stage piezoelectric-based electrical energy generators for low and variable speed rotary machinery (2009)

A novel class of two-stage piezoelectric-based electrical energy generators is presented for rotary machinery in which the input speed is relatively low, varies significantly over time, and is even reversing. This class of energy generators is highly suitable for applications such as wind mills, turbo-machinery used to harvest tidal flows, and the like. Current technology uses magnet-and-coil-based rotary generators. However, to make the generation cycle efficient, gearing or other similar mechanisms have to be used to increase the input speed to the generator. Variable speed-control mechanisms are also usually needed to achieve high mechanical to electrical energy conversion efficiency. This novel class of electrical energy generators uses a decoupled two-stage system. The harvesting environment (wind, tidal flow, etc.) directly provides input to the primary system. The low and varying input motion is then used to successively excite an array of vibrating elements (secondary system). The key advantage is that by having two decoupled systems, the low speed and highly varying input motion is converted into constant and much higher frequency mechanical vibrations, which are then harvested using piezoelectric elements. As a result, by eliminating the need for gearing and speed control mechanisms, the system complexity and cost - including those related to maintenance and service - is significantly reduced. Additionally, these novel generators can expand the application of power generation to much slower input speeds than are harvestable using current technology.
High-dose alfacalcidol improves anaemia in patients on haemodialysis (1997)

High-dose alfacalcidol is efficient in anaemic patients with moderate hyperparathyroidism on maintenance HD and has a direct effect on erythropoietic cells regardless of serum calcium and iPTH levels.
Folate supplementation and methotrexate treatment in rheumatoid arthritis: a review (2003)

We propose that folic acid supplements be prescribed routinely to all patients receiving MTX for the treatment of RA. We recommend a pragmatic dosing schedule of 5 mg of oral folic acid given on the morning following the day of MTX administration.
Person identification from aerial footage by a remote-controlled drone (2017)

Abstract Remote-controlled aerial drones (or unmanned aerial vehicles; UAVs) are employed for surveillance by the military and police, which suggests that drone-captured footage might provide sufficient information for person identification. This study demonstrates that person identification from drone-captured images is poor when targets are unfamiliar (Experiment 1), when targets are familiar and the number of possible identities is restricted by context (Experiment 2), and when moving footage is employed (Experiment 3). Person information such as sex, race and age is also difficult to access from drone-captured footage (Experiment 4). These findings suggest that such footage provides a particularly poor medium for person identification. This is likely to reflect the sub-optimal quality of such footage, which is subject to factors such as the height and velocity at which drones fly, viewing distance, unfavourable vantage points, and ambient conditions.
Fabrication of Imprint Stamp by Using Nanosphere Lithography and Its Utilization to Photoluminescence Enhancement (2008)

Nanosphere lithography is proposed as a new technique for the fabrication of nanoscale pillars on p-GaN layer. This technique is an easy and simple process using a self-assembled monolayer of spheres, which act as etching masks to form pillars on a Si3N4 substrate, that could be utilized as a stamp for UV-based imprint lithography. We can apply the UV-based imprint technique in the field of solid-state lighting in order to extract more lights to out-world by texturing the outer surface of the light emitting diodes (LED) structure. Photoluminescence intensity from the pillar patterned GaN layer was higher than that from the unpatterned GaN layer by 2.5 times.
Clinical case management for the chronically mentally ill: A conceptual analysis (1988)

Abstract Clinical case management for chronic mental patients combines the clinical sensitivity and interpersonal skills of the psychotherapist with the creativity and action orientation of the environmental architect.
Initial synchronization of TDMA communication in distributed real-time systems (2003)

This paper discusses the startup phase of a TDMA protocol intended for safety-critical real-time systems using a broadcast bus. The protocol contains sender id in each message, and nodes send messages of equal size in a fixed order. A single channel media is used and data and synchronization information must therefore share the same channel. Synchronization is challenging, since clocks must be synchronized to guarantee successful transmissions, and successful transmissions rely on synchronized clocks. We describe three different start-up algorithms and evaluate them with respect to complexity, resynchronization time and performance in the presence of transient faults.
The design and evaluation of a high-performance soft keyboard (1999)

The design and evaluation of a high performance soft keyboard for mobile systems are described. Using a model to predict the upper-bound text entry rate for soft keyboards, we designed a keyboard layout with a predicted upper-bound entry rate of 58.2 wpm. This is about 35% faster than the predicted rate for a QWERTY layout. We compared our design (OPTI) with a QWERTY layout in a longitudinal evaluation using five participants and 20 45-minute sessions of text entry. Average entry rates for OPT1 increased from 17.0 wpm initially to 44.3 wpm at session 20. The average rates exceeded those for the QWERTY layout after the 10 session (about 4 hours of practice). A regression equation (R = .997) in the form of the power-law of learning predicts that our upper-bound prediction would be reach at about session 50.