gebhart/patrepeval huggingface dataset:
One pot synthesis of chiral block copolymers combining controlled radical polymerisation and enzymatic ring opening polymerisation (2003)

Plasma androstenedione and oestrone concentrations were measured in 72 postmenopasual women. The women included some who had undergone oophorectomy, some with osteoporosis, and normal controls; they were matched for years since menopause. Both hormone concentrations were significantly reduced in the women with osteoporosis. The women who had undergone oophorectomy had hormone concentrations intermediate between the normal and osteoporotic values. Oestrogen deficiency secondary to low androstenedione levels is a major risk factor in postmenopausal osteoporosis, and may be caused by failure of ovarian stromal androgen secretion or some abnormality in the pituitary-adrenal axis.
Agarwood oil (<i>Aquilaria agallocha</i> Roxb.). Its composition and eight new valencane‐, eremophilane‐ and vetispirane‐ derivatives (1995)

Abstract The profile of the total extract of agarwood oil ( Aquilaria agallocha Roxb.) is discussed and eight new sesquiter‐penoids are presented: two with the eremophilane‐skeleton ( rel‐(2R,8S,8aR )‐2‐(1,2,3,5,6,7,8,8a‐octahydro‐8,8a‐dimethy1‐2‐naphthyl)‐prop‐2‐en‐1‐ol ( 1 , eremophila‐9,11(13)‐dien‐12‐ol) and rel ‐( 3R,7R,9R,10S )‐9,10‐dimethyl‐6‐methylene‐4‐oxatricyclo[7.4.0.0 3,7 ]tridec‐1‐ene ( 2 , 8,12‐epoxy‐eremophila‐9,11(13)‐diene)), one with the valencane‐skeleton ( rel ‐( 2R,8S,8aR )‐2‐(1,2,6,7,8,8a‐hexahyro‐8,8a‐dimethyl‐2‐naphthyl)‐propan‐2‐ol ( 3 , valenca‐1(10),8‐dien‐11‐ol)) and four with the vetispirane‐skeleton ( rel‐(5R,10R) ‐(2‐isopropylidene‐10‐methyl‐spiro[4,5]dec‐6‐ene‐6‐carbaldehyde ( 4 , vetispira‐2(11),6‐dien‐14‐al), rel‐(5R,7R,10R) ‐2‐isopropylidene‐10‐methyl‐6‐rnethylene‐spiro[4.5]decan‐7‐01 ( 5 , vetispira‐2(11),6(14)‐dien‐7‐01), rel‐(1R,2R) ‐9‐isopropyl‐2‐rnethyl‐8‐oxatricyclo[7.2.1.0 1,6 ]dodec‐5‐ene ( 6 , 2,14‐epoxy‐vetispir‐6‐ene) and rel‐(1R,2R) ‐(9‐isopropyl‐2‐methyl‐8‐oxatricyclo[7.2.1.0 1,6 ]dodeca‐4,6‐diene ( 7 , 2,14‐epoxy‐vetispira‐6(14),7‐diene)). 2‐(1,2,3,5,6,7,8,8a‐octahydro‐8,8a‐dimethyl‐2‐naphthyl)‐propanal ( 8 , valenc‐ or eremophil‐9‐en‐12‐al) is tentatively identified.
A novel laser resonator for fractal modes (2018)

Mathematical self-similar fractals manifest identical replicated patterns at every scale. Recently, fractals have found their way into a myriad of applications. In optics, it has been shown that manipulation of unstable resonator parameters such as cavity length, curvatures of mirrors, the design of aperture and its transverse position can reveal self-similar fractal patterns in the resonators eigenmodes. Here, we present a novel laser resonator that can generate self-similar fractal output modes. This resonator has a special plane termed self-conjugate, during each round trip inside the cavity, is imaged upon itself with either a magnification or demagnification depending on the direction of beam propagation inside the cavity. By imaging an aperture placed in the self-conjugate plane inside the cavity, we qualitatively show the fractal behaviour occurring at various scales which, are given by powers of the magnification at the self-conjugate plane. We computed the fractal dimension of the patterns we generated and obtained non-integer values, as is expected for fractals.
On the Role of the Support in Pt Anode Catalyst Degradation under Simulated H<sub>2</sub> Fuel Starvation Conditions (2018)

In order to learn more about the effect of H2 fuel starvation on the degradation of Pt anode catalysts and in particular on the role of the support therein, we have investigated the impact of a simulated fuel starvation procedure on three different polymer electrolyte fuel cell anode catalysts, Pt/C, Pt/TiO2 and Pt/TiO2+C, by differential electrochemical mass spectrometry (DEMS) measurements. Monitoring the potential as well as the mass spectrometric signal transients of the possible reaction products CO2 (carbon oxidation reaction – COR) and O2 (oxygen evolution reaction – OER) upon switching from H2-saturated to N2-saturated electrolyte under galvanostatic oxidation conditions, we find a rapid increase of the potential to values at about 1.75 V upon electrolyte exchange, together with the onset of CO2 formation and O2 evolution, where the latter dominates at high potentials. The ratio of O2 evolution and carbon support oxidation differs significantly for different catalyst supports, with the COR contributing more for the carbon-containing catalysts in the initial stage of the fuel starvation period, and the OER prevailing for the Pt/TiO2 catalyst over the whole starvation time. The complex interplay between different catalyst degradation processes during fuel starvation is discussed.
Kinetics and mechanism of the decomposition of cobalt dioxygen complexes of the binucleating macrocyclic ligand BISBAMP [3,9,17,23,29,30-hexaaza-6,20-dioxatricyclo[23.3.1.111,15]triaconta-1(28),11,13,15(30),25(29),26-hexaene] (1989)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTKinetics and mechanism of the decomposition of cobalt dioxygen complexes of the binucleating macrocyclic ligand BISBAMP [3,9,17,23,29,30-hexaaza-6,20-dioxatricyclo[23.3.1.111,15]triaconta-1(28),11,13,15(30),25(29),26-hexaene]Manuel Garcia Basallote, Dian Chen, and Arthur E. MartellCite this: Inorg. Chem. 1989, 28, 18, 3494–3499Publication Date (Print):September 1, 1989Publication History Published online1 May 2002Published inissue 1 September 1989https://doi.org/10.1021/ic00317a020RIGHTS & PERMISSIONSArticle Views46Altmetric-Citations15LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (715 KB) Get e-Alerts Get e-Alerts
Mobility and distribution of a cell surface glycoprotein and its interaction with other membrane components (1977)

Fluorescence photobleaching recovery and immunofluorescence methods have been used to study the lateral mobility and topographical distribution of a major cell surface glycoprotein (CSP). Both endogenous CSP and fluorescent-labeled exogenous CSP bind to the cell surface in a fibrillar pattern and are immobile on the experimental time scale. Azide, vinblastine, and cytochalasin B do not alter the immobility and cell surface distribution of the CSP molecules. Therefore, oxidative phosphorylation and the cytoskeleton do not seem to be responsible for the properties of the bound glycoprotein. The presence of immobile CSP fibrils does not, however, impede the diffusion of a lipid probe, a ganglioside analogue, or various surface antigens. Therefore, the fibrils apparently do not form a "barrier" across the lipid phase of the plasma membrane. In contrast, concanavalin A binds to CSP and is largely immobile in regions rich in CSP. The presence of immobile concanavalin A receptors in areas or on cells lacking CSP indicates that other types of immobile concanavalin A receptors also exist.CSP does not bind to lipid bilayers composed of phosphatidylcholine or oxidized cholesterol. It does bind to dextran-coated bilayers as a diffuse distribution of mobile molecules that can patch after addition of antibodies to CSP. The latter result suggests that CSP molecules do not interact strongly with other CSP molecules under these conditions. Exogenous CSP binds to regions on the cell surface that already bear CSP. In view of the apparent weakness of CSP-CSP interactions on the lipid bilayer, it seems possible that the assembly of CSP fibrils is nucleated by cell surface components in addition to CSP.
Solid-State Reaction and Vacancy-Type Defects in Bilayer Fe/Hf Studied by the Slow Positron Beam (2015)

The positron annihilation lifetimes and the Doppler broadening by slow positron beam are measured in thin Fe films with thickness 500 nm, a thin Hf film with thickness 100 nm, and the bilayer Fe (50 nm)/Hf (50 nm) on quartz glass substrate. We have analyzed the behavior in vacancy-type defects in each layer through some deposition temperatures and annealing. It is observed that the thin Fe film, the thin Hf film, and the bilayer Fe (50 nm)/Hf (50 nm) already contain many vacancy-type defects. We have investigated the change of densities of the vacancy-carbon complex and the small vacancy-cluster with carbons, through solid-state amorphization of Fe (50 nm)/Hf (50 nm) bilayer.
Millimeter Wave Communications with Reconfigurable Antennas (2018)

The highly sparse nature of propagation channels and the restricted use of radio frequency (RF) chains at transceivers limit the performance of millimeter wave (mmWave) multiple-input multiple- output (MIMO) systems. Introducing reconfigurable antennas to mmWave can offer an additional degree of freedom on designing mmWave MIMO systems. This paper provides a theoretical framework for studying the mmWave MIMO with reconfigurable antennas. We present an architecture of reconfigurable mmWave MIMO with beamspace hybrid analog-digital beamformers and reconfigurable antennas at both the transmitter and the receiver. We show that employing reconfigurable antennas can provide throughput gain for the mmWave MIMO. We derive the expression for the average throughput gain of using reconfigurable antennas, and further simplify the expression by considering the case of large number of reconfiguration states. In addition, we propose a low-complexity algorithm for the reconfiguration state and beam selection, which achieves nearly the same throughput performance as the optimal selection of reconfiguration state and beams by exhaustive search.
Regiospecific synthesis of 3-substituted-5-alkylisoxazoles by modification of the dilithiooxime route to isoxazoles (1982)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTRegiospecific synthesis of 3-substituted-5-alkylisoxazoles by modification of the dilithiooxime route to isoxazolesDennis H. Hoskin and R. A. OlofsonCite this: J. Org. Chem. 1982, 47, 26, 5222–5225Publication Date (Print):December 1, 1982Publication History Published online1 May 2002Published inissue 1 December 1982https://pubs.acs.org/doi/10.1021/jo00147a042https://doi.org/10.1021/jo00147a042research-articleACS PublicationsRequest reuse permissionsArticle Views150Altmetric-Citations18LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Synthesis and Structure of the Silver(I) Complexes [Ag<sub>2</sub>(C<sub>4</sub>H<sub>6</sub>O<sub>4</sub>N)NO<sub>3</sub>]·H<sub>2</sub>O and Ag<sub>6</sub>(C<sub>6</sub>H<sub>6</sub>O<sub>6</sub>N)<sub>2</sub> for the Formulation of Silver Inks in Nanoimprint Lithography (2020)

Two new carboxylate silver(I) complexes, namely [Ag 2 (C 4 H 6 O 4 N)]NO 3 · H 2 O or [Ag 2 (HIDA)]NO 3 · H 2 O with IDA = iminodiacetate (1) and Ag 6 (C 6 H 6 O 6 N) 2 or Ag 6 (NTA) 2 with NTA = nitrilotriacetate (2) are synthesized and characterized by X‐ray powder diffraction, thermal analysis and infrared spectroscopy. Rietveld refinement reveals [Ag 2 (HIDA)]NO 3 · H 2 O to form a 2D coordination polymer while Ag 6 (NTA) 2 forms a 3D network, both featuring short Ag(d 10 )–Ag(d 10 ) contacts. The resulting complexes are suitable precursors for the printing of silver structures at low temperature, in particular for micro and submicrometer patterns obtained via nanoimprint lithography. The patterns reveal low specific resistivity ( ρ ≈ 10 –7 Ω m) and good transmittance (> 50 %) in the visible range enabling applications in optoelectronic devices.
History-based device graphical user-interfaces (2010)

Due to limited screen space on mobile computers, device GUIs can span multiple screens-requiring tedious scrolling and tabbing for commands. History-based device GUIs can significantly reduce required space by only presenting the commands a user typically needs based on the user's behavior over a short training period. Moreover, history-based UIs and model-based UI generation are symbiotic. Generation relieves programmers from the overhead of logging and interpreting the interaction histories. Conversely, history-based user-interaction noticeably lowers inherent UI generation time by omitting unneeded commands.
Guideline systems for deep-sea deployments (1974)

systems can be operated in water depths to at least 4,500 feet without serious entanglement problems. Payload rotation produced during the deployment test was found to be small and results from variations in static forces. The design of guideline hardware and at-sea handling is discussed. In addition to surface motion compensation, a means for releasing in-line torque must be provided to achieve entanglement-free operations.
Behavior of Gaseous Microemboli in Extracorporeal Circuits: Air versus Co<sub>2</sub> (2006)

Current ECC systems fail to eliminate gas entering the circuit, leading rather to microbubble dispersion. CO2 is much faster resorbed within the circuit than room air. In open heart surgery as valvular operations, CO2 insufflation into the operative field is protective, as we have demonstrated in our models.
Evaluation of Abdominal-transhiatal Resection with Mediastinoscopy for Carcinoma of the Esophagogastric Junction (2011)

はじめに : 食道胃接合部に対する定義は一定の見解を得ておらず治療法の選択に苦慮することが多い．今回，食道癌取扱い規約に定められる食道胃接合部癌に対し，非開胸・縦隔鏡補助下経裂孔的下部食道切除術と左開胸開腹連続切開術との治療成績を比較検討し，至適アプローチ法，中・下縦隔リンパ節郭清の意義につき検討した．方法 : 対象は2001年1月から2008年12月までに食道胃接合部癌と診断し根治術を施行した23例（左開胸開腹連続切開（left thoracoabdominal approach；以下，LTAと略記）8例，非開胸・縦隔鏡補助下経裂孔的下部食道切除（abdominal-transhiatal approach；以下，THと略記）15例）．治療成績につき比較検討した．結果 : 最大腫瘍径，食道切除長に有意差を認めなかった．手術時間はLTAと比較しTHは有意に短く（p＜0.001），出血量もTHが少なかった（p＜0.001）．中・下縦隔リンパ節転移は23例中7例（30.4%）に認められた．術後平均観察期間は3.5年であるが，再発は7例に認めるもすべて遠隔再発であり，1例を除き全例原病死となった．考察 : THはLTAと比較しても同等の成績を得ることが可能であり，必ずしも開胸操作は必要ないことが考えられた．中・下縦隔リンパ節郭清に関しては，組織型を問わず根治を期待できる症例に関しては必要であると考えられた．
ChemInform Abstract: CONVERSION OF ALKYL CHLORIDES TO BROMIDES, SELECTIVE REACTIONS OF MIXED BROMOCHLOROALKANES, AND HALOGEN EXCHANGE (1976)

Abstract Primäre Alkylchloride, z.B. (I), werden in Gegenwart von Äthylbromid, N‐Methyl‐2‐pyrrolidinon (PYRR) und katalytischen Mengen von NaBr quantitativ in die Bromide (II) übergeführt.
Prognostic importance of left ventricular function after angioplasty or thrombolysis for acute myocardial infarction. (2001)

The benefits of primary coronary angioplasty compared with streptokinase are well sustained during long-term follow-up.
Large-effect pleiotropic or closely linked QTL segregate within and across ten US cattle breeds (2014)

This largest GWAS ever performed in beef cattle, led us to discover several novel across-breed and breed-specific large-effect pleiotropic QTL that cumulatively account for a significant percentage of additive genetic variance (e.g. more than a third of additive genetic variance of birth and mature weights; and calving ease direct in Hereford). These results will improve our understanding of the biology of growth and body composition in cattle.
Lack of <i>Mycobacterium tuberculosis</i>–specific interleukin‐17A–producing CD4<sup>+</sup> T cells in active disease (2013)

Protective immunity to Mycobacterium tuberculosis (Mtb) is commonly ascribed to a Th1 profile; however, the involvement of Th17 cells remains to be clarified. Here, we characterized Mtb-specific CD4(+) T cells in blood and bronchoalveolar lavages (BALs) from untreated subjects with either active tuberculosis disease (TB) or latent Mtb infection (LTBI), considered as prototypic models of uncontrolled or controlled infection, respectively. The production of IL-17A, IFN-γ, TNF-α, and IL-2 by Mtb-specific CD4(+) T cells was assessed both directly ex vivo and following in vitro antigen-specific T-cell expansion. Unlike for extracellular bacteria, Mtb-specific CD4(+) T-cell responses lacked immediate ex vivo IL-17A effector function in both LTBI and TB individuals. Furthermore, Mtb-specific Th17 cells were absent in BALs, while extracellular bacteria-specific Th17 cells were identified in gut biopsies of healthy individuals. Interestingly, only Mtb-specific CD4(+) T cells from 50% of LTBI but not from TB subjects acquired the ability to produce IL-17A following Mtb-specific T-cell expansion. Finally, IL-17A acquisition by Mtb-specific CD4(+) T cells correlated with the coexpression of CXCR3 and CCR6, currently associated to Th1 or Th17 profiles, respectively. Our data demonstrate that Mtb-specific Th17 cells are selectively undetectable in peripheral blood and BALs from TB patients.
Perianal Crohn’s disease and hidradenitis suppurativa: a possible common immunological scenario (2015)

The presence of numerous CD4+ CD161+ lymphocytes in fistula and HS lesion curettages suggests that these cells may play a pathogenic role, and candidates CD161 as a possible biological target for medical treatment.
The ASC-Inclusion Perceptual Serious Gaming Platform for Autistic Children (2018)

“Serious games” are becoming extremely relevant to individuals who have specific needs, such as children with an autism spectrum condition (ASC). Often, individuals with an ASC have difficulties in interpreting verbal and nonverbal communication cues during social interactions. The ASC-Inclusion EU-FP7 funded project aims to provide children who have an ASC with a platform to learn emotion expression and recognition, through play in the virtual world. In particular, the ASC-Inclusion platform focuses on the expression of emotion via facial, vocal, and bodily gestures. The platform combines multiple analysis tools, using onboard microphone and webcam capabilities. The platform utilizes these capabilities via training games, text-based communication, animations, video, and audio clips. This paper introduces current findings and evaluations of the ASC-Inclusion platform and provides detailed description for the different modalities.
Transactions Papers Distributed Space-Time Block Coding (2006)

In this paper, a new class of distributed space-time block codes (DSTBCs) is introduced. These DSTBCs are designed for wireless networks which have a large set of single-antenna relay nodes , but at any given time only a small, a priori unknown subset of nodes can be active. In the proposed scheme, the signal transmitted by an active relay node is the product of an information-carrying code matrix and a unique node signature vector of length . It is shown that existing STBCs designed for co-located antennas are favorable choices for the code matrix, guaranteeing a diversity order of if nodes are active. For the most interesting case, , the performance loss entailed by the distributed implementation is an- alytically characterized. Furthermore, efficient methods for the op- timization of the set of signature vectors are provided. Depending on the chosen design, the proposed DSTBCs allow for low-com- plexity coherent, differential, and noncoherent detection, respec- tively. Possible applications include ad hoc and sensor networks employing decode-and-forward relaying.
Modulation of the cellular uptake and localization of conjugated Trojan peptides. (2007)

International audience
Ionic Liquids (2019)

Abstract An overview of the field of ionic liquids is presented, including the nomenclature and types of ionic liquids. Their synthesis and purification methods are described, along with typical characterisation procedures and general physico‐chemical properties. The various applications of ionic liquids are also summarised including in batteries, in green chemistry as low vapour pressure solvents, in medicinal chemistry and in protein stabilisation.
Chromatographic Evidence for the Presence of Multiple Tachykinins in the Bovine Adrenal Medulla (1992)

Among the mammalian tachykinins, substance P (SP) has been shown to be the most potent at modulating the response due to nicotinic acetylcholine receptor stimulation of bovine adrenal chromaffin cells. SP-like immunoreactivity has been detected in nerve terminals innervating the adrenal medulla; however, little is known of the presence of other tachykinins in this tissue. In this study, reverse-phase HPLC was used to fractionate peptides in bovine adrenal medullary extracts, and the fractions were analyzed by radioimmunoassay using antisera to SP or neurokinin A (NKA). The results show that both NKA- and SP-like immunoreactivities are present in the adrenal medulla. The presence of neurokinin B is also indicated. The presence of multiple tachykinins in this tissue raises questions as to their functions in the adrenal medulla.
Salmonella typhimurium–Associated Severe Protracted Diarrhea in Infants and Young Children (1990)

Eleven (13.8%) children (4-14 months; mean of 7.8 +/- 3.6 months) presenting with protracted diarrhea (duration greater than 21 days) and weight loss had associated infection with Salmonella typhimurium. All had documented weight loss of 16-25% and progressive clinical deterioration. On admission, they had high purging rates (greater than 4 ml/kg/h), hyponatremia (5/11), mucosal injury, and malabsorption as measured by 1 h blood D-xylose, fecal alpha 1-antitrypsin, and oral fat tolerance test. Diarrhea was secretory in 8 of 11 and fecal sodium was high (54-142 mEq/L; mean of 102 +/- 27 mEq/L). The organism showed multiple drug resistance. All patients received antibiotics (amikacin and nalidixic acid/norfloxacin) for 10-14 days, which was followed by rapid improvement in clinical status and absorption studies. The two youngest patients died. Due to ethical reasons, an untreated control group was not included. Use of appropriate antibiotics may benefit children with S. typhimurium-associated severe protracted diarrhea and rapid progressive weight loss.
Antitumor effect of dicyclohexylammonium sulfate, a potent inhibitor of spermidine, synthase. (1981)

The antitumor effect of dicyclohexylammonium sulfate (DCHA), a potent inhibitor of spermidine synthase, was tested on mice inoculated with Ehrlich ascites carcinoma, Ehrlich solid carcinoma and solid sarcoma-180. DCHA prolonged the survival time of mice bearing Ehrlich ascites carcinoma at doses of 50 approximately 100 mg/kg/day X 5. For Ehrlich solid carcinoma and solid sarcoma-180 the tumor growth was suppressed significantly at doses of 2 approximately 50 mg/kg/day X 10. The spermidine concentration of the tumor cells was lowered, while the spermine concentration hardly changed. The depletion of spermidine in the tumor cells might be a cause of the suppression of tumor growth.