gebhart/patrepeval huggingface dataset:
The Cytoplasmic Membrane-proximal Domain of the HtrII Transducer Interacts with the E-F Loop of Photoactivated Natronomonas pharaonis Sensory Rhodopsin II (2004)

The structures of the cytoplasmic loops of the phototaxis receptor sensory rhodopsin II (SRII) and the membrane-proximal cytoplasmic domain of its bound transducer HtrII were examined in the dark and in the light-activated state by fluorescent probes and cysteine cross-linking. Light decreased the accessibility of E-F loop position 154 in the SRII-HtrII complex, but not in free SRII, consistent with HtrII proximity, which was confirmed by tryptophans placed within a 5-residue region identified in the HtrII membrane-proximal domain that exhibited Forster resonance energy transfer to a fluorescent probe at position 154 in SRII. The Forster resonance energy transfer was eliminated in the signaling deficient HtrII mutant G83F without loss of affinity for SRII. Finally, the presence of SRII and HtrII reciprocally inhibit homodimer disulfide cross-linking reactions in their membrane-proximal domains, showing that each interferes with the others self-interaction in this region. The results demonstrate close proximity between SRII-HtrII in the membrane-proximal domain, and in addition, light stimulation of the SRII inhibition of HtrII cross-linking was observed, indicating that the contact is enhanced in the photoactivated complex. A mechanism is proposed in which photoactivation alters the SRII-HtrII interaction in the membrane-proximal region during the signal relay process.
Scan Islands - a scan partitioning architecture and its implementation on the Alpha 21364 processor (2003)

The paper presents a pragmatic scan partitioning architecture that allows less than perfect scan design in high performance, VLSI circuits to cost-effectively achieve test development and manufacturing test goals. The paper then describes an implementation of the architecture on Compaq's Alpha 21364 microprocessor.
Coupling of Alkenes and Alkynes: Synthesis of the C1−C11 and C18−C28 Fragments of Miyakolide (2008)

A transition metal-mediated, atom-economical approach toward the crucial A and D rings of miyakolide is described. A Pd-catalyzed alkyne-alkyne coupling/6- endo- dig cyclization is employed to assemble the A ring fragment. The key D ring pyran is constructed utilizing an Ru-catalyzed alkene-alkyne coupling followed by a Pd-catalyzed allylic alkylation to establish the all-cis stereochemistry.
Experimental Trichosporon Infection in Persistently Granulocytopenic Rabbits: Implications for Pathogenesis, Diagnosis, and Treatment of an Emerging Opportunistic Mycosis (1992)

Disseminated Trichosporon infection, an uncommon but emerging opportunistic mycosis due to Trichosporon beigelii, is frequently difficult to diagnose, refractory to treatment, and associated with a high attributable mortality. Models of disseminated and gastrointestinal Trichosporon infection were developed in persistently granulocytopenic rabbits. The patterns of infection resembled those of clinical disease, including cutaneous lesions, chorioretinitis, renal infection, pulmonary infection, and antigenemia cross-reactive with cryptococcal capsular polysaccharide. Antigenemia, an early manifestation of disseminated Trichosporon infection, originated in vivo from a fibrillar extracellular matrix. Trichosporon organisms disseminated from the gastrointestinal tract to visceral tissue in colonized immunosuppressed rabbits, whereas there was no dissemination from the gastrointestinal tract of otherwise normal rabbits. The antifungal triazoles, fluconazole and SCH 39304, were most active; maximum tolerated doses of amphotericin B and liposomal amphotericin B were ineffective. Trichosporon antigenemia declined in response to antifungal therapy. These findings contribute to improved understanding of the pathogenesis, diagnosis, and treatment of disseminated Trichosporon infection.
Integrating and Visualizing Tropical Cyclone Data Using the Real Time Mission Monitor (2009)

The Real Time Mission Monitor (RTMM) is a visualization and information system that fuses multiple Earth science data sources, to enable real time decision-making for airborne and ground validation experiments. Developed at the NASA Marshall Space Flight Center, RTMM is a situational awareness, decision-support system that integrates satellite imagery, radar, surface and airborne instrument data sets, model output parameters, lightning location observations, aircraft navigation data, soundings, and other applicable Earth science data sets. The integration and delivery of this information is made possible using data acquisition systems, network communication links, network server resources, and visualizations through the Google Earth virtual globe application. RTMM is extremely valuable for optimizing individual Earth science airborne field experiments. Flight planners, scientists, and managers appreciate the contributions that RTMM makes to their flight projects. A broad spectrum of interdisciplinary scientists used RTMM during field campaigns including the hurricane-focused 2006 NASA African Monsoon Multidisciplinary Analyses (NAMMA), 2007 NOAA-NASA Aerosonde Hurricane Noel flight, 2007 Tropical Composition, Cloud, and Climate Coupling (TC4), plus a soil moisture (SMAP-VEX) and two arctic research experiments (ARCTAS) in 2008. Improving and evolving RTMM is a continuous process. RTMM recently integrated the Waypoint Planning Tool, a Java-based application that enables aircraft mission scientists to easily develop a pre-mission flight plan through an interactive point-and-click interface. Individual flight legs are automatically calculated on the fly. The resultant flight plan is then immediately posted to the Google Earth-based RTMM for interested scientists to view the planned flight track and subsequently compare it to the actual real time flight progress. We are planning additional capabilities to RTMM including collaborations with the Jet Propulsion Laboratory in the joint development of a Tropical Cyclone Integrated Data Exchange and Analysis System (TC IDEAS) which will serve as a web portal for access to tropical cyclone data, visualizations and model output.
Network characterization of a finite array of folded-slot antennas for spatial power combining application (2003)

An electromagnetic modeling procedure for a CPW-based spatial power combining array with folded-slot antennas is presented. The concept of a direct extraction of the network parameters from the method of moment matrix is explained. Calculations of the network parameters of a unit cell and an array are presented.
Adaptive optics technologies for industrial and medical applications (2005)

Adaptive optics is a maturing technology. Developed primarily for big-science applications in the military and astronomy areas adaptive optics systems, the components produced to implement adaptive systems, are increasingly finding more down-to-earth uses.
Role of mast cells, eosinophils and IL‐5 in the development of airway hyperresponsiveness in sensitized mice (1996)

These data suggest that mast cells play an important role in the onset of airway hyperreactivity but do not play a role in the production of IL-5 and eosinophilia. Furthermore, indicate that the inhibition of IL-5 is not always associated with a reduction in antigen-induced airway hyperreactivity in mice.
A Randomized, Double-Blind, Multicenter Trial Comparing Transdermal Scopolamine Plus Ondansetron to Ondansetron Alone for the Prevention of Postoperative Nausea and Vomiting in the Outpatient Setting (2009)

TDS + OND reduces PONV compared with OND alone. This is achieved with a reduction in adverse events.
Use of Mixture Equations for Estimating Theoretical Complex Permittivities from Measurements on Porous or Powder Ceramic Specimens (1995)

Two dielectric mixture equations were used in order to obtain estimates of theoretical permittivities from measurements on porous or powder ceramic specimens. Complex permittivities of alumina ( Al 2 O 3 ) and zirconia ( ZrO 2 ) were measured using a coaxial probe technique over the temperature and frequency ranges of 25-1200° C and 0.2-4.0 GHz, respectively. It appears that the equations are applicable to porous specimens but not always applicable to powder specimens without knowledge of density change and effect of porosity on permittivity change.
Concept Development of a Pneumatically Driven, Fixed Root Circulation Controlled Helicopter (2007)

<div class="htmlview paragraph">Circulation control technologies have been applied to fixed wing aircraft for approximately four decades. During those early tests an increase in lift coefficient of nearly four times the unaltered airfoil was achieved. Applying these or similar technologies, particularly inducing the coanda effect through blowing slots to rotorcraft blades, can enhance the performance of the helicopter.</div> <div class="htmlview paragraph">The increase in lift coefficient of the rotor blade provides more options to the designer, including decreasing the rotor diameter, decreasing the rotor speed, increasing the payload capacity, or a combination of all three. By either reducing the diameter and/or the rotor speed the blade tip speed can be reduced, thus allowing a higher forward flight speed. Retreating blade stall can also be reduced by applying circulation control to the leading edge of the rotor blade.</div> <div class="htmlview paragraph">A three phase design process is envisioned for the development of a pneumatically driven, fixed root circulation control helicopter rotor. The first phase would be to develop a high lift rotor blade. This would require the modification of conventional helicopter airfoils to incorporate rounded trailing edges and active blowing slots. The second phase would be to determine the ability to cycle the blowing slot velocity to minimize the asymmetry of lift during maneuvering flight, eliminating the need to physically change the pitch of the blade. The third phase would build on the fixed root circulation control blade by adding a jet of air at the tip of the blade, to provide the power to turn the rotor minimizing the torque transferred to the helicopter fuselage.</div> <div class="htmlview paragraph">In the transfer of fixed wing, active circulation control technologies to rotary wing aircraft several major obstacles need to be addressed and overcome. Some of these are, the supply of air to the active circulation control blowing slots given the limited space within the rotor blades and the transmission of the airflow from the non-rotating fuselage to the rotating plan-form of the rotor.</div>
ChemInform Abstract: A Concise Synthesis of the Molecular Framework of Pleuromutilin. (2011)

Abstract Two pleuromutilin analogues (VI) and (X) are prepared via a diastereoselective 1,4‐conjugate addition of cyanide (III) to enones and a ring‐closing metathesis as key steps.
Polarized TCR-Transgenic Th17 Cells Resemble Th1 Cells in Their Capacity to Adoptively Transfer Ocular Inflammation, but Differ in Other Biological Activities (130.44) (2007)

Abstract The role of Th17 lymphocytes in immunopathogenic processes has been well established, although little is known about their mode of action and other biological activities. Here, we prepared polarized populations of TCR-transgenic (Tg) Th1 or Th17 cells specific against hen egg lysozyme (HEL) and compared each line for its capacity to adoptively transfer ocular inflammation into Tg recipients expressing lens-associated HEL, as well as for other biological activities. To establish each line, naive CD4+ cells were cultured in the presence of HEL and "cocktails" containing cytokines and antibodies known to drive polarization to Th1 or Th17. Successful polarization of Th1 and Th17 lines was confirmed by intracellular expression and release into the culture medium of IFNγ or IL17, respectively. Surface marker expression was determined by flow cytometry of cultured cells. Recipient eyes were examined histologically. Polarized cells were also tested for their capacity to induce splenomegaly in recipient mice (Chen et al JI 2006). Our results showed that Th1 and Th17 cells were similarly immunopathogenic, transferring ocular inflammation at doses as low as 0.2 million. Histological comparison of eyes from each group, however, revealed slight although discernible differences between Th1 and Th17 recipients. The two populations also differed in their expression of surface markers, particularly in CD49d and CD62L. Finally, Th17 cells were remarkably less efficient than Th1 cells in their capacity to induce splenomegaly in recipient mice.
Potential differences in the inferior vena cava and between cava and extravascular electrode at leg contraction in man. (1992)

When a voluntary adult male contracted his leg muscles, electric potential differences were recorded between platinum electrodes positioned inside the vena cava or between the vena cava and the grounded skin. Two experiments confirm that potential differences at leg contractions in man have a similar appearance as those in the rat at pain-evoked contractions of leg muscles. Platinum electrodes were used in man. The potential differences obtained are thereafter compared with recordings with Ag-AgCl electrodes in salt-bridges in the rat. Slow potential waves with superimposed irregular potential oscillations are recorded in man as previously found in the rat using platinum or Ag-AgCl electrodes. The findings indicate that vascular-interstitial routes participate in a vascular-interstitial-neuromuscular closed circuit, which is activated at contraction of the muscles.
Studies on the control of plasminogen activator production by cultured human embryonic lung cells: Requirements for inhibition by corticosteroids (1980)

The ability of actinomycin D to interfere with the dexamethasone-mediated inhibition of plasminogen activator (PA) production by human-embryonic lung (HuEL) cells has been examined. The enzyme produced by HuEL cells in the presence of both dexamethasone and actinomycin D appears to be the product of de novo protein synthesis, as determined by the dependence of PA production on active protein synthesis and the net increase in total PA during the course of an experiment. Inhibition of RNA synthesis must be continuous to maintain PA production in the presence of dexamethasone, since reinitiation of RNA synthesis causes an immediate loss of PA activity in the cells. Cordycepin and alpha-amanitin also prevent dexamethasone-mediated inhibition of PA in HuEL cells, indicating that the RNA whose synthesis must be prevented is of the mRNA class. These experiments imply that PA production in HuEL cells may be under translational as well as transcriptional control.
Shear Orientation and Rheology of a Lamellar Polystyrene-Polyisoprene Block Copolymer (1995)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTShear Orientation and Rheology of a Lamellar Polystyrene-Polyisoprene Block CopolymerS. S. Patel, R. G. Larson, K. I. Winey, and H. WatanabeCite this: Macromolecules 1995, 28, 12, 4313–4318Publication Date (Print):June 1, 1995Publication History Published online1 May 2002Published inissue 1 June 1995https://pubs.acs.org/doi/10.1021/ma00116a038https://doi.org/10.1021/ma00116a038research-articleACS PublicationsRequest reuse permissionsArticle Views953Altmetric-Citations123LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
<title>Framework for dynamically reconfigurable video codec using multiple coding tools</title> (1998)

In this paper, we propose framework for dynamically reconfigurable video codec. We introduce the concept of a virtual codec and a virtual tool to facilitate the use of multiple codec structures and multiple coding tools in a single video codec. Existing coding standards as well as new codec structures and coding tools can be integrated seamlessly in the proposed codec. The experimental results show that when implementing a standard codec such as H.263 the proposed codec can achieve a comparable performance to dedicated standard codecs. The results also demonstrate the codec's ability to use multiple coding tools and codec structures which are useful for implementing MSDL for MPEG-4 video.
ChemInform Abstract: REACTION OF NICKEL ELECTRODE SURFACES WITH ANIONIC METAL‐CYANIDE COMPLEXES: FORMATION OF PRECIPITATED SURFACES (1984)

Abstract Komplexe, die beim Mischen mit Ni" in Lösung Niederschläge bilden, eignen sich auch zur Derivatisierung von Nickelelektrodenoberflächen.
ChemInform Abstract: Synthesis and Transformations of Metallocycles. Part 15. A Novel Method for β‐Vinylation of α‐Olefins with AlEt3 under the Action of Ni‐ and Zr‐Containing Catalysts. (1995)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
How to Manipulate Cold Atoms (2003)

Since Bose-Einstein condensates were first realized in 1995, experimentalists have focused on characterizing and manipulating these weakly interacting systems. In their Perspective,
 Cirac and Zoller
 look ahead toward the next challenge for atomic physics: strongly interacting atomic systems that may be of use in quantum computing and may clarify fundamental properties of quantum mechanics. They explain how optical lattices can be used to tune the interactions between cold atoms and how a quantum simulator may be constructed. The latter may enable the first quantum computers that can outperform ordinary computers for nontrivial problems.
Studies in Organic Sulfur Compounds. V.<sup>1</sup> Synthesis of 21-Thiolacetates of Adrenal Cortical Hormones (1953)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTStudies in Organic Sulfur Compounds. V.1 Synthesis of 21-Thiolacetates of Adrenal Cortical HormonesCarl Djerassi and A. L. NussbaumCite this: J. Am. Chem. Soc. 1953, 75, 15, 3700–3703Publication Date (Print):August 1, 1953Publication History Published online1 May 2002Published inissue 1 August 1953https://pubs.acs.org/doi/10.1021/ja01111a028https://doi.org/10.1021/ja01111a028research-articleACS PublicationsRequest reuse permissionsArticle Views107Altmetric-Citations12LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Extraction with Spinodal Decomposition – Experiment and Simulation (2006)

Abstract Experimental results on the growth and velocity of droplets (up to 0.45 mm/s) during the temperature‐induced phase separation of the 3‐methoxypropionitrile/water solvent system as well as a variety of theoretical methods used to study the demixing dynamics are presented. Due to computational costs, the simulation with Molecular Dynamics (MD) is feasible only for very short times (ps) and miniscule boxes (Å). Dissipative Particle Dynamics (DPD), where a coarse‐grained model of the system is employed, allows nanosecond simulations in a box with more than 13 million atoms in a diffusion‐dominated regime. Finally, the influence of the diffusion/convection ratio during the separation in the μs scale is studied by use of a code based on Model H for both instantaneous and non‐instantaneous quenching cases. Structural information and macroscopic parameters, such as interfacial tension, can be derived from the molecular simulations.
Full and partial posttraumatic stress disorder: findings from a community survey (1997)

These findings in an epidemiologic sample underscore observations from patient and military groups that many traumatized persons suffer from a subsyndromal form of PTSD. These persons with partial PTSD, although somewhat less impaired than persons with the full syndrome, nonetheless exhibit clinically meaningful levels of functional impairment in association with their symptoms. This subthreshold form of PTSD may be especially prevalent in women. Additional study of partial PTSD is warranted.
Charts, Interaction-Free Grammars, and the Compact Representation of Ambiguity (1997)

Recently researchers working in the LFG framework have proposed algorithms for taking advantage of the implicit context-free components of a unification grammar [Maxwell 96]. This paper clarifies the mathematical foundations of these techniques, provides a uniform framework in which they can be formally studied and eliminates the need for special purpose runtime data-structures recording ambiguity. The paper posits the identity: Ambiguous Feature Structures = Grammars, which states that (finitely) ambiguous representations are best seen as unification grammars of a certain type, here called ``interaction-free'' grammars, which generate in a backtrack-free way each of the feature structures subsumed by the ambiguous representation. This work extends a line of research [Billot and Lang 89, Lang 94] which stresses the connection between charts and grammars: a chart can be seen as a specialization of the reference grammar for a given input string. We show how this specialization grammar can be transformed into an interaction-free form which has the same practicality as a listing of the individual solutions, but is produced in less time and space.