gebhart/patrepeval huggingface dataset:
Shear- vs. nanotopography-guided control of growth of endothelial cells on RGD-nanoparticle-nanowell arrays (2013)

Endothelialization of therapeutic cardiovascular implants is essential for their intravascular hemocompatibility. We previously described a novel nanowell-RGD-nanoparticle ensemble, which when applied to surfaces led to enhanced endothelialization and retention under static conditions and low flow rates. In the present study we extend our work to determine the interrelated effects of flow rate and the orientation of ensemble-decorated surface arrays on the growth, adhesion and morphology of endothelial cells. Human umbilical vascular endothelial cells (HUVECs) were grown on array surfaces with either 1 μm × 5 μm spacing ("parallel to flow") and 5 μm × 1 μm spacing ("perpendicular to flow") and were exposed to a range of shear stress of (0 to 4.7 ± 0.2 dyn·cm-2 ), utilizing a pulsatile flow chamber. Under physiological flow (4.7 ± 0.2 dyn·cm-2), RGD-nanoparticle-nanowell array patterning significantly enhanced cell adhesion and spreading compared with control surfaces and with static conditions. Furthermore, improved adhesion coincided with higher alignment to surface patterning, intimating the importance of interaction and response to the array surface as a means of resisting flow detachment. Under sub-physiological condition (1.7 ± 0.3 dyn·cm-2; corresponding to early angiogenesis), nanowell-nanoparticle patterning did not provide enhanced cell growth and adhesion compared with control surfaces. However, it revealed increased alignment along the direction of flow, rather than the direction of the pattern, thus potentially indicating a threshold for cell guidance and related retention. These results could provide a cue for controlling cell growth and alignment under varying physiological conditions.
Resistance of polish potato cultivars to PVY Strains (1998)

*INRA, URD, BP 29, 35653 Le Rheu Cedex Diffusion du document : INRA, URD, BP 29, 35653 Le Rheu Cedex
Inclusion Complexes of Poly(neopentyl glycol sebacate) with Cyclodextrins (2001)

Poly(neopentyl glycol sebacate) (PNGS) is able to form inclusion complexes with three cyclodextrins (α-CD, β-CD, and γ-CD). The complexes are characterized by XRD, 13C CP/MAS NMR, FTIR, 1H NMR, and TGA. The complexes possess a column structure wherein some structural change occurs when the “raw” γ-CD/PNGS complex is washed and dried. It is suggested that α-CD can “squeeze” over the bulky dimethyl groups and settle on and complex the thinner part of the polymer chain.
Defect Engineering of Iron-Rich Orthosilicate Cathode Materials with Enhanced Lithium-Ion Intercalation Capacity and Kinetics (2019)

Defect engineering via nonstoichiometric composition control can serve as an effective strategy to tune the electronic and crystal structures of intercalation compounds, as has been recently evidenced in Li-rich cathode materials. To extend this strategy in another direction, Fe-richness as opposed to Li-richness is investigated in improving the electrochemical performance of a promising cathode material, Li2FeSiO4 (LFS). Nonstoichiometric LFS compounds in orthorhombic Pmn21 phase with up to 8% Fe-excess are successfully synthesized via controlled hydrothermal synthesis. It is demonstrated that, in addition to the higher electron capacity from the accessible Fe2+/Fe3+ redox couple, the presence of excess Fe enhances the intercalation kinetics vis-à-vis the stoichiometric composition. From combined electrochemical evaluation and first-principles DFT calculations, the enhanced kinetics are rationalized by the introduction of the FeLi• + VLi′ defect pair and newly generated electron conducting states from the creation of local Fe–O–Fe configurations. Moreover, the Fe-rich structure facilitates Fe migration to the Li-site due to a lower energy barrier than that of stoichiometric LFS, hence apparently leading to faster phase transformation from Pmn21 toward the cycled inverse Pmn21 phase. More generally, this study opens alternative defect and compositional engineering approaches in designing next generation intercalation materials with improved electrochemical performance.
Shockley and Tamm surface states in photonic crystals (2006)

Existence of the Shockley surface states in photonic crystals is demonstrated for the first time. We show that in photonic crystals, the surface states of defect chain with unit cell containing one defect are the Tamm rather than Shockley states as commonly assumed. The Shockley states can appear only in the defect chain with unit cell containing more than one defect. We first analyze the surface states using the tight-binding theory. Theoretical predictions are confirmed by the numerical simulations.
<i>MSH6</i> Mutations Arise in Glioblastomas during Temozolomide Therapy and Mediate Temozolomide Resistance (2009)

MSH6 mutations are selected in glioblastomas during temozolomide therapy both in vitro and in vivo and are causally associated with temozolomide resistance.
Terahertz Computed Tomography of NASA Thermal Protection System Materials (2011)

A terahertz axial computed tomography system has been developed that uses time domain measurements in order to form cross-sectional image slices and three-dimensional volume renderings of terahertz-transparent materials. The system can inspect samples as large as 0.0283 cubic meters (1 cubic foot) with no safety concerns as for x-ray computed tomography. In this study, the system is evaluated for its ability to detect and characterize flat bottom holes, drilled holes, and embedded voids in foam materials utilized as thermal protection on the external fuel tanks for the Space Shuttle. X-ray micro-computed tomography was also performed on the samples to compare against the terahertz computed tomography results and better define embedded voids. Limits of detectability based on depth and size for the samples used in this study are loosely defined. Image sharpness and morphology characterization ability for terahertz computed tomography are qualitatively described.
Corrections - Developmental Changes of Mammalian Lactic Dehydrogenases (1964)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCorrections - Developmental Changes of Mammalian Lactic DehydrogenasesI. Fine, N. Kaplan, and D. KuftinecCite this: Biochemistry 1964, 3, 3, 469Publication Date (Print):March 1, 1964Publication History Published online30 October 2003Published inissue 1 March 1964https://pubs.acs.org/doi/10.1021/bi00891a600https://doi.org/10.1021/bi00891a600research-articleACS PublicationsRequest reuse permissionsArticle Views12Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
G-lambda and EnLIGHTened: Wrapped In Middleware Co-allocating Compute and Network Resources Across Japan and the US (2007)

This paper describes innovative architectures and techniques for reserving and coordinating highly distributed resources, a capability required for many large scale applications. In the fall of 2006, Japan’s G-lambda research team and the United States’ EnLIGHTened Computing research team used these
Flight Test Results of a Powered Parafoil System (Aeroflyer) (1976)

Abstract : Eighty flight tests of the AeroFlyer are carried out in order to demonstrate that it can fly and in order to obtain flight performance data. All of these tests are summarized with particular emphasis on the data obtained from the three flight tests at Wright Field. These demonstrate that the AeroFlyer can take off directly from the ground, climb, turn right and left, glide and achieve a precision soft landing. The data from the three flights at Wright Field is analyzed and compared with performance predictions. The turns were accomplished by rudder, by wing deflection, and by combinations of both. The representative flight velocity is 29 mph and the rate of climb is 60 ft/min for an AeroFlyer weighing 579.3 lbs. using a 400 sq. ft. Parafoil. The horsepower required for level flight was 12. The minimum radius of turn demonstrated was 175 ft. and the nominal landing roll was estimated to be less than 20 ft. This performance data is used to predict optimum parafoil performance for flight system weights ranging from 10 lbs. to 10,000 lbs. (Author)
Colorimetric Determination of Phenolic Resins (1956)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTColorimetric Determination of Phenolic ResinsM. H. Swann and D. J. WeilCite this: Anal. Chem. 1956, 28, 9, 1463–1465Publication Date (Print):August 21, 1956Publication History Published online1 May 2002Published inissue 21 August 1956https://pubs.acs.org/doi/10.1021/ac60117a033https://doi.org/10.1021/ac60117a033research-articleACS PublicationsRequest reuse permissionsArticle Views89Altmetric-Citations5LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Constant Pressure Molecular Modeling of Six Optimised Titanium Oxide Polymorphs: Metal Oxide Semiconductors (2010)

Six polymorphs of Titania which include Rutile, Anatase, Brookite, high-pressure Brookite, the columbite-type TiO2-II and Corundum-like type CLT, have been modelled under constant pressure using the General Utility Lattice Program (GULP) with results comparing favourably with the classical and long standing molecular dynamics model by Matsui and Akaogi (1991). Using energy (Buckingham potential model) minimization criteria with no need for thermal expansivity correction, the simulation yielded satisfactory mechanical and thermodynamic properties, and produced stable optimized nanoparticle for the polymorphs investigated except the CLT. Our procedure and results were validated by conducting a Molecular Dynamic optimization for all six polymorphs and using the Broyden-Fletcher-Goldfarb-Shanno: BFGS optimizer with a secondary switch to Rational Functional Optimization- RFO with satisfactory results. Our simulations suggests that enhanced performances for wide-bandgap semiconductors and of photovoltaic cell electrodes can be a reality with lower heat capacity Titania polymorphs.
The Role of Properdin in the Assembly of the Alternative Pathway C3 Convertases of Complement (2005)

Complement is a powerful host defense system that contributes to both innate and acquired immunity. There are three pathways of complement activation, the classical pathway, lectin pathway, and alternative pathway. Each generates a C3 convertase, a serine protease that cleaves the central complement protein, C3. Nearly all the biological consequences of complement are dependent on the resulting cleavage products. Properdin is a positive regulator of complement activation that stabilizes the alternative pathway convertases (C3bBb). Properdin is composed of multiple identical protein subunits, with each subunit carrying a separate ligand-binding site. Previous reports suggest that properdin function depends on multiple interactions between its subunits with its ligands. In this study I used surface plasmon resonance assays to examine properdin interactions with C3b and factor B. I demonstrated that properdin promotes the association of C3b with factor B and provides a focal point for the assembly of C3bBb on a surface. I also found that properdin binds to preformed alternative pathway C3 convertases. These findings support a model in which properdin, bound to a target surface via C3b, iC3b, or other ligands, can use its unoccupied C3b-binding sites as receptors for nascent C3b, bystander C3b, or pre-formed C3bB and C3bBb complexes. New C3bP and C3bBP intermediates can lead to in situ assembly of C3bBbP. The full stabilizing effect of properdin on C3bBb would be attained as properdin binds more than one ligand at a time, forming a lattice of properdin: ligand interactions bound to a surface scaffold.
Diving Depths of the Weddell Seal (1964)

Dives as deep as 350 meters have been recorded for the Weddell seal in the waters of McMurdo Sound, Antarctica. It is suggested that Weddell seals possess a well-developed navigational system which enables them to swim long distances under thick ice shelves where light and breathing holes are limited.
A Framework for Sparse Matrix Code Synthesis from High-level Specifications (2000)

We present compiler technology for synthesizing sparse matrix code from (i) dense matrix code, and (ii) a description of the index structure of a sparse matrix. Our approach is to embed statement instances into a Cartesian product of statement iteration and data spaces, and to produce efficient sparse code by identifying common enumerations for multiple references to sparse matrices. The approach works for imperfectly-nested codes with dependences, and produces sparse code competitive with hand-written library code for the Basic Linear Algebra Subroutines (BLAS).
Accuracy of Model-Based Iterative Reconstruction for CT Volumetry of Part-Solid Nodules and Solid Nodules in Comparison with Filtered Back Projection and Hybrid Iterative Reconstruction at Various Dose Settings: An Anthropomorphic Chest Phantom Study (2019)

MIR was the most accurate algorithm for volume measurements of both PSNs and SNs in comparison with FBP and HIR at low-dose as well as standard-dose settings. Specifically, MIR was effective in the volume measurement of the smallest PSNs and SNs.
Drug activity prediction using multiple-instance learning via joint instance and feature selection (2013)

The empirical results demonstrate that the selected instances (prototype conformers) and features (pharmacophore fingerprints) have competitive discriminative power and the convergence of the selection process is also fast.
[Modulation of the tumoral progression by anti-idiotypic antibodies of angiogenesis factors]. (1996)

We took advantage of the anti-idiotypic strategy to design circulating probes mimicking the biological effects of VEGF (vascular endothelial growth factor) or FGF2 (fibroblast growth factor 2). The activation of the VEGF receptor KDR/flk-1 induced endothelial cell proliferation but not their migration, whereas that of the FGF receptor FGF-R1 gave opposite results. The long lasting delivery of KDR/flk-1 agonists, but not that of FGF-R1, in nude mice grafted with tumor fragments enhanced the tumor volume. Microscopic examination showed an increase in both the vascularization and the proliferation of cancer cells. In contrast, no difference in cell proliferation was observed within normal tissues.
Normalized pulsed energy thresholding in a nonlinear optical loop mirror (2015)

We demonstrate for the first time, to the best of our knowledge, that a Sagnac interferometer can threshold the energies of pulses. Pulses below a given threshold T are suppressed, while those above this threshold are normalized. The device contains an in-loop tunable isolator and 10.4 m of a highly doped silica fiber. We derive an analytical model of the nonlinear optical loop mirror's pulse energy transfer function and show that its energy transfer function approximates a step function for very high phase shifts (>π). We reveal some limitations of this approach, showing that a step-function transfer function necessarily results in pulse distortion in fast, nonresonant all-optical devices.
Preparation of 9‐fluoro‐9‐deoxy‐<i>N</i>‐[2‐<sup>14</sup>C]acetylneuraminic acid (1984)

9‐Fluoro‐9‐deoxy‐ N ‐[2‐ 14 C]acetylneuraminic acid has been prepared from 6‐fluoro‐6‐deoxy‐ N ‐acetylmannosamine and [2‐ 14 C]pyruvic acid for the first time, using Clostridium perfringens N ‐acetylneuraminate pyruvate‐lyase (EC 4.1.3.3). The fluoro sugar was activated by CMP‐ N ‐acetylneuraminic acid synthase and CTP to yield CMP‐9‐fluoro‐9‐deoxy‐ N ‐[2‐ 14 C]acetylneuraminic acid. Both products were obtained in good yield (60 and 30%, respectively). The radioactive sugar in its activated form is glycosidically attached to asialo‐α 1 ‐acid glycoprotein by sialyltransferase and can be removed by the action of Vibrio cholerae sialidase. The reaction rates of the enzymes studied are lower with the 9‐fluoro derivatives than with the N ‐acetylneuraminic acid substrates.
ChemInform Abstract: PHOSPHORYLIERTE UND THIOPHOSPHORYLIERTE BENZAZOLYLIDEN‐ UND BENZAZOLYLHARNSTOFFE (1975)

Abstract Durch Umsetzung der Isocyanato(thio)‐phosphate und Isocyanato(thio)‐phosphonate (II) mit den 2‐Aminoazolen (I) entstehen die Hanrstoffe (III).
Simulations and experiments of SiC heteroepitaxial growth on Si(001) surface (1993)

Mechanism of SiC heteroepitaxial growth by the carbonization of the Si(001) surface was studied at the atomic scale using molecular dynamics (MD) simulations and molecular beam epitaxy (MBE) experiments. Heteroepitaxial growth of single crystal 3c-SiC on the Si(001) surface (3c-SiC[001]∥Si[001] and 3c-SiC[110]∥Si[110]) was observed in both the MD simulations and MBE experiments. Breaking of the Si—Si bonds and shrinkage of the [110] Si rows with C atoms are possible mechanisms for the heteroepitaxial growth of SiC on Si(001). Microscopic structures and mechanisms of the twin formations and pit formations are discussed. Ultraviolet light irradiation is proposed and confirmed to enhance the epitaxial growth of SiC in the MBE experiments.
Helicons and Nonresonant Cyclotron Absorption in Semiconductors. II.<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mrow><mml:msub><mml:mrow><mml:mi mathvariant="normal">Hg</mml:mi></mml:mrow><mml:mrow><mml:mn>1</mml:mn><mml:mo>−</mml:mo><mml:mi>x</mml:mi></mml:mrow></mml:msub></mml:mrow><mml:mrow><mml:msub><mml:mrow><mml:mi mathvariant="normal">Cd</mml:mi></mml:mrow><mml:mrow><mml:mi>x</mml:mi></mml:mrow></mml:msub></mml:mrow><mml:mi mathvariant="normal">Te</mml:mi></mml:math> (1969)

We have used microwave helicons of 23 and 70 GHz and nonresonant cyclotron absorption to measure the carrier densities, effective masses, and mobilities of electrons in ${\mathrm{Hg}}_{1\ensuremath{-}x}{\mathrm{Cd}}_{x}\mathrm{Te}$ for $0.135\ensuremath{\le}x\ensuremath{\le}0.203$. Most measurements were made at 77\ifmmode^\circ\else\textdegree\fi{}K, but some values are reported for 1.3\ifmmode^\circ\else\textdegree\fi{}K. Carrier concentrations at 77\ifmmode^\circ\else\textdegree\fi{}K ranged from 8\ifmmode\times\else\texttimes\fi{}${10}^{20}$ to 2\ifmmode\times\else\texttimes\fi{}${10}^{22}$${\mathrm{m}}^{\ensuremath{-}3}$ and were sufficiently low to enable us to measure ${m}^{*}$ close to the conduction-band edge. The mass values, in the range $0.004{m}_{0}\ensuremath{-}0.010{m}_{0}$, are in good agreement with values calculated from Kane's expression for the conduction band using literature values for the energy gap, its variation with temperature and alloy concentration, and the momentum matrix element, $P$. One specimen with $x=0.149$ was studied from 77 to 185\ifmmode^\circ\else\textdegree\fi{}K. Over this range the mobility was closely proportional to ${T}^{\ensuremath{-}2}$. The variation of electron density permitted an estimate of the effective mass of the holes, ${{m}_{h}}^{*}=0.71{m}_{0}$.
Stability and design criteria studies for compressed air energy storage reservoirs. Progress report, FY 1977. (1978)

Progress made during FY-1977 in establishing design criteria to ensure the successful operation and long-term stability of Compressed Air Energy Storage (CAES) reservoirs in underground porous media, such as aquifers is summarized. The formulation of pertinent criteria is important since the long-term stability of air storage reservoirs is probably the item of greatest risk to the successful demonstration and commercialization of the CAES concept. The study has been divided into four phases: (1) state-of-the-art survey, (2) analytical modeling studies, (3) laboratory studies, and (4) field testing. The first of these phases, the state-of-the-art survey for air storage in porous reservoirs, has been completed on schedule and is reported in Section 2. Sections 3 and 4 are progress reports on Phases 2 and 3. No work has been done on Phase 4. It is planned that the field testing phase of this study will be carried out in conjunction with the Department of Energy/Electric Power Research Institute (DOE/EPRI) CAES Demonstration Program. This phase is not scheduled to begin until FY-1979.
Modification of Cell Attachment Properties of Tissue-Culture Polystyrene Surface by Silver-Negative-Ion Implantation. (1999)

Modification of the tissue-culture polystyrene (TCPS) surface by the silver-negative-ion implantation was investigated with respect to contact angle, selective cell attachment properties and control of cell orientation. Negative-silver ions were implanted into TCPS at a condition in energy and dose region : 5-30 keV and 1 × 1014-1 × 1016 ions/cm2. By this implantation, the surface of TCPS was changed to be hydrophobic, and loosed its cell attachment property. In the patterned implantation through a mask with slits of 40 μm-wide and 4 mm-long with a spacing of 40 μm, the cells attached on the unimplanted region of TCPS. In addition, most of the attached cells aligned along a stripe pattern.
Hexamethylhexaphenylcyclohexasilan (1972)

Abstract The preperation of hexamethylhexaphenylcyclohexasilane (I) from CH3(C6H5)SiCl2 with Na/K - alloy is described. The ring-size was proved by reaction of I with HJ and LiCH3 to give dodecamethyl-cyclohexasilane, which was identical with an authentic sample of this compound.
[Malignant peritoneal mesothelioma: apropos a new case]. (1993)

Prognosis for patients with malignant peritoneal mesothelioma is very poor, and most patients are beyond cure by the time the diagnosis has been made. The pathogenesis of this uncommon neoplasm seems to be related to asbestos and radiation exposure. The authors report a case of diffuse peritoneal mesothelioma in a 33-year-old man. Since the patient complained of aspecific symptoms and both biochemical and "imaging" studies did not provide useful informations for a definitive diagnosis, an exploratory laparotomy was performed. Intraoperative histological findings demonstrated the presence of a malignant peritoneal mesothelioma which had spread all over the omentum; considering the inoperability assessment of this case, the operation was completed and the patient was dismissed with an adjuvant chemo-therapy. Five weeks later the patient died.