gebhart/patrepeval huggingface dataset:
<i>Wolbachia</i> , normally a symbiont of <i>Drosophila</i> , can be virulent, causing degeneration and early death (1997)

Wolbachia, a maternally transmitted microorganism of the Rickettsial family, is known to cause cytoplasmic incompatibility, parthenogenesis, or feminization in various insect species. The bacterium-host relationship is usually symbiotic: incompatibility between infected males and uninfected females can enhance reproductive isolation and evolution, whereas the other mechanisms enhance progeny production. We have discovered a variant Wolbachia carried by Drosophila melanogaster in which this cozy relationship is abrogated. Although quiescent during the fly's development, it begins massive proliferation in the adult, causing widespread degeneration of tissues, including brain, retina, and muscle, culminating in early death. Tetracycline treatment of carrier flies eliminates both the bacteria and the degeneration, restoring normal life-span. The 16s rDNA sequence is over 98% identical to Wolbachia known from other insects. Examination of laboratory strains of D. melanogaster commonly used in genetic experiments reveals that a large proportion actually carry Wolbachia in a nonvirulent form, which might affect their longevity and behavior.
Highly Stable and Finely Tuned Magnetic Fields Generated by Permanent Magnet Assemblies (2013)

Permanent magnetic materials are the only magnetic source that can be used to generate magnetic fields without power consumption or maintenance. Such stand-alone magnets are very attractive for many scientific and engineering areas, but they suffer from poor temporal field stability, which arises from the strong sensitivity of the magnetic materials and mechanical support to temperature variation. In this work, we describe a highly efficient method useful to cancel the temperature coefficient of permanent magnet assemblies in a passive and accurate way. It is based on the combination of at least two units made of magnetic materials with different temperature coefficients arranged in such a way that the ratio of the fields generated by each unit matches the ratio of their effective temperature coefficients defined by both the magnetic and mechanical contributions. Although typically available magnetic materials have negative temperature coefficients, the cancellation is achieved by aligning the fields generated by each unit in the opposite direction. We demonstrate the performance of this approach by stabilizing the field generated by a dipolar Halbach magnet, recently proposed to achieve high field homogeneity. Both the field drift and the homogeneity are monitored via nuclear magnetic resonance spectroscopy experiments. The results demonstrate the compatibility of the thermal compensation approach with existing strategies useful to fine-tune the spatial dependence of the field generated by permanent magnet arrays.
Antiviral Antibodies Are Necessary for Control of Simian Immunodeficiency Virus Replication (2007)

To better define the role of B cells in the control of pathogenic simian immunodeficiency virus (SIV) replication, six rhesus monkeys were depleted of B cells by intravenous infusion of rituximab (anti-CD20) 28 days and 7 days before intravaginal SIVmac239 inoculation and every 21 days thereafter until AIDS developed. Although the blood and tissues were similarly depleted of B cells, anti-SIV immunoglobulin G (IgG) antibody responses were completely blocked in only three of the six animals. In all six animals, levels of viral RNA (vRNA) in plasma peaked at 2 weeks and declined by 4 weeks postinoculation (PI). However, the three animals prevented from making an anti-SIV antibody response had significantly higher plasma vRNA levels through 12 weeks PI (P = 0.012). The remaining three B-cell-depleted animals made moderate anti-SIV IgG antibody responses, maintained moderate plasma SIV loads, and showed an expected rate of disease progression, surviving to 24 weeks PI without developing AIDS. In contrast, all three of the B-cell-depleted animals prevented from making anti-SIV IgG responses developed AIDS by 16 weeks PI (P = 0.0001). These observations indicate that antiviral antibody responses are critical in maintaining effective control of SIV replication at early time points postinfection.
Base hydrolysis of halopentaamminecobalt(III) ions (1968)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTBase hydrolysis of halopentaamminecobalt(III) ionsDavid A. Buckingham, I. I. Olsen, and Alan M. SargesonCite this: Inorg. Chem. 1968, 7, 1, 174–175Publication Date (Print):January 1, 1968Publication History Published online1 May 2002Published inissue 1 January 1968https://pubs.acs.org/doi/10.1021/ic50059a041https://doi.org/10.1021/ic50059a041research-articleACS PublicationsRequest reuse permissionsArticle Views35Altmetric-Citations11LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Steroids and related natural products. LIII. Bufadienolides. 6. Synthesis of 17.beta.-(6-.alpha.-pyronyl)androstanes (1970)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSteroids and related natural products. LIII. Bufadienolides. 6. Synthesis of 17.beta.-(6-.alpha.-pyronyl)androstanesGeorge R. Pettit, John C. Knight, and Cherry L. HeraldCite this: J. Org. Chem. 1970, 35, 5, 1393–1398Publication Date (Print):May 1, 1970Publication History Published online1 May 2002Published inissue 1 May 1970https://pubs.acs.org/doi/10.1021/jo00830a030https://doi.org/10.1021/jo00830a030research-articleACS PublicationsRequest reuse permissionsArticle Views98Altmetric-Citations10LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
<scp>HPV</scp>‐negative carcinoma of the uterine cervix: a distinct type of cervical cancer with poor prognosis (2014)

An HC2-negative result is an uncommon finding in women with CC, but in almost half of these cases HPVs are identified by more sensitive techniques. CCs with confirmed HPV-negativity are more frequently adenocarcinomas, and seem to be associated with worse DFS.
High-Temperature Operation of Normally Off-Mode AlGaN/GaN Heterostructure Field-Effect Transistors with p-GaN Gate (2011)

We demonstrated the high-temperature operation of normally off-mode heterostructure field-effect transistors (HFETs) with a p-GaN gate. The HFETs with a p-GaN gate were operated in the normally off mode at 350 °C. The temperature dependence of their performance was compared with the results of simulation.
The Cycloaddition Strategy for the Synthesis of Natural Products Containing Carbocyclic Seven‐Membered Rings (2006)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Development and Evaluation of Selected Mobility Applications for VII (2010)

This report describes the development of two of the three mobility applications that PATH is developing and evaluating under the sponsorship of the FHWA Exploratory Advanced Research Program, with cost share funding provided by PATH TO 6224. These applications are intended to use DSRC wireless communications among vehicles and between vehicles and the roadway infrastructure to improve mobility on limited-access highways. The first application combines ramp metering with variable speed limits to enhance control of traffic so that traffic flow breakdowns can be deferred or avoided at bottleneck locations. The second application uses vehicle-vehicle communication to improve the performance of adaptive cruise control systems so that they can operate safely with smaller longitudinal gaps and vehicle-roadside communication to provide adjustments to their set speed and gap settings to adapt to changes in local traffic conditions.
Molecular Solid Solution of Tetraphenyl-porphin and Silver Tetraphenylporphin (1967)

Abstract Molecular solid solutions have received surprisingly little attention in the past, yet we must study them before we can hope to understand why their natural occurrence appears to be so much more limited than that of their inorganic counterparts. Examples might conceivably have escaped attention because single-crystal X-ray work has not been carried out on “impure” molecular crystals. Porphyrins are well suited for solid solution study. Because of their biological importance, their molecular structure is known in detail from numerous refined crystal structures that have appeared in recent years.1 Methods of porphyrin synthesis have been perfected over many years in the laboratory of Professor A. H. Corwin at The Johns Hopkins University.
531. Some synthetical investigations in isocoumarin chemistry (1958)

J. B. Jones and A. R. Pinder, J. Chem. Soc., 1958, 2612 DOI: 10.1039/JR9580002612
LIVER FLUKES: ALGORITHM OF DIAGNOSIS AND TREATMENT. ANALYSIS OF CASES AND REVIEW (2019)

The liver flukes Opisthorchis felineus, O. viverrini and Clonorchis sinensis are endemic in Russia, Southeast Asia and Far East where more than 18 million people are estimated to be infected. Opisthorchiasis remains the public health significance in Russia, and Western Siberia must be considered as highly endemic region for opisthorchiasis in the Russian Federation. High infection rates result from hazardous behaviours, centuries-old raw-food culture, a poor knowledge of opisthorchiasis, ecological complexities and complex biology. The infection is associated with several hepatobiliary diseases, including cholangiocarcinoma. Praziquantel is the only option for treatment of Opisthorchiasis . The detection the parasite’s eggs in stool still referred as gold standard. Recent research has provided new diagnostic technologies applicable to diagnosis, treatment and control. Despite some progress in their control, liver flukes continue to be a major public health problem in endemic areas.
Aspects of the electroslag welding process (2010)

The electroslag welding (ESW) process has been investigated utilizing consumable guide welding procedures. Electroslag welding employing large square cross-section electrodes was also studied. The study of the process parameters is of importance in understanding the role which they play in determining the grain size attained in the heat affected zone of the resultant weld. The large grain size adversely effects the impact strength: the grain size is a direct consequence of the thermal history. The thermal history of the base metal was determined during welding for various physical configurations and welding schedules. The welding parameters having the major effect on the thermal history are: mode of welding, electrode immersion depth, slag depth, welding velocity and specific power input. The penetration of the parent metal and size of the heat-affected zone as well as the grain size have been shown to be a consequence of the thermal history. The quazi-steady state electrical and temperature distributions in the slag are seen to determine the temperature distribution in the metal. The preferred modes of welding are alternating current (AC) and direct current reverse polarity (DCRP) with direct current straight polarity (DCSP) being unacceptable due to the high inclusion content of the weld when DCSP is employed. The electrode immersion depth, or interelectrode gap, has been found to determine the volume of the effective heat source and thus the temperature and electrical distributions. The slag depth and electrode velocity are the principal factors which determine the interelectrode gap when the slag chemistry and physical configuration are constant. There exist ranges of slag depth and electrode velocity values outside of which welding is not achieved. An analytical model has been employed which adequately describes thick plate welding practice, but which only applies to thin plate welds in a qualitative manner. In this model, an empirical equation has been used to calculate electrode immersion values which compare favourably with the measured values. In addition,the Bastein method of grain size calculation has been applied to the thermal histories obtained experimentally and has been found to be applicable. In welds where impact strength is an important design criteria the weld/HAZ grain size is an important variable. We conclude that no combination of ESW process parameters will lead to an acceptable HAZ grain size giving HAZ impact values comparable with the parent plate. In such cases full heat treatment of the HAZ would be mandatory.
Fabrication of Fully Isolated nFETs Using Oxidized Porous Silicon (2010)

SOI (Silicon on Insulator) technology is an option in improving device performance as smaller devices run into scaling challenges. The devices for this study were fabricated using a FIPOS (Fully Isolated Porous Oxidized Silicon) process, which results in localized SOJ active regions. The oxidation of electrochemically etched porous silicon (PSi) has demonstrated success in the formation of device quality localized SOl for CMOS applications [1,2]. The formation of PSi can be done selectively by controlling the Fermi level in areas to be etched or not etched, which is typically (lone by adjusting the level of (loping [1]. An alternative method is to introduce a reversible donor species such as protons [2] or fluorine (this work) for the selective formation of islands of crystalline silicon surrounded by porous silicon. Implanted fluorine in silicon has demonstrated a donor effect upon annealing at low temperature (600°C), which is reversible as the fluorine outdiffuses (luring higher temperature annealing (1000°C). This technique has been used to form ~ crystalline silicon active regions with thickness less than 200 nm completely surrounded by oxidized porous silicon [3], shown in figure 2. This study involves the fabrication and characterization of nFETs on the active areas to investigate the electronic integrity of the silicon device regions.
Reductive<i>C</i>-Alkylation of Nitroarenes with Grignard Reagents; Synthesis of Alkyl-amino-arenes (1978)

A simple method for the conversion of nitrobenzothiazoles in amines is reported
Nonmetal-metal transition in metal–molten-salt solutions (1996)

The method of ab initio molecular dynamics, based on finite-temperature density-functional theory, is used to study the nonmetal-metal transition in two different metal--molten-salt solutions, ${\mathrm{K}}_{\mathit{x}}$(KCl${)}_{1\mathrm{\ensuremath{-}}\mathit{x}}$ and ${\mathrm{Na}}_{\mathit{x}}$(NaBr${)}_{1\mathrm{\ensuremath{-}}\mathit{x}}$. As the excess metal concentration is increased the electronic density becomes delocalized and percolating conducting paths are formed, making a significant dc electrical conductivity possible. This marks the onset of the metallic regime. By calculating several electronic and structural properties, remarkable differences between the two solutions are observed. The anomalous behavior of ${\mathrm{Na}}_{\mathit{x}}$(NaBr${)}_{1\mathrm{\ensuremath{-}}\mathit{x}}$, typical of all the Na-NaX solutions, is found to be related to the strong attractive interaction between the sodium ions and the excess electrons. \textcopyright{} 1996 The American Physical Society.
Crystal structure of [1,2-ethylene-1,1'-bis(η5-tetrahydroindenyl)]-chloro-[η2-N,C-3,4,5,6-tetrafluoropyridyl]zirconium(IV), ZrCl(C5F4N)(C20H24) (2005)

Article Crystal structure of [1,2-ethylene-1,1'-bis(η5-tetrahydroindenyl)]-chloro-[η2-N,C-3,4,5,6-tetrafluoropyridyl]zirconium(IV), ZrCl(C5F4N)(C20H24) was published on April 1, 2005 in the journal Zeitschrift für Kristallographie - New Crystal Structures (volume 220, issue 1-4).
[Endothelial function in contact lens-induced deep corneal opacities]. (1989)

Deep stromal and preendothelial corneal opacities have been described to be a problem of growing importance in contact lens wearers, above all in those with a more than ten-year-old history of contact lens wearing. In the present study the corneal endothelial permeability of 21 patients with a more than ten-year-old history of contact lens (HEMA 38%) wearing has been determined and compared with that of an age-matched group of 8 healthy individuals without ocular disease. The corneal endothelial permeability has been measured by a computerized automated fluorophotometer (Coherent Radiation Fluorotron Master) after topical application of a Na-fluorescein solution according to the method described by Jones and Maurice. The corneal endothelial permeability of contact lens wearers with deep corneal opacities has been found to be significantly (p = 0.05) increased when compared with contact lens wearers without corneal opacities. Contact lens wearers without corneal opacities showed no significant increase of their endothelial permeability in comparison to the control group.
Collecting and Measuring Nociceptive and Inflammatory Mediators in Surgical Wounds (2008)

We describe a methodology by which we are able to collect and measure inflammatory and nociceptive biochemical mediators at the surgical wound site. Collecting site-specific biochemical markers allows us to evaluate the relationship between surgical wound and serum levels;determine any associations between mediator release, pain and analgesic consumption; and evaluate the effect of systemic and peripheral drug administration on surgical wound biochemistry.This methodology has been applied to healthy women undergoing elective cesarean delivery with spinal anesthesia. Wound exudate and serum mediators, in conjunction with pain scores and analgesics consumption were measured at 1, 6, 24, and 48 hours post-cesarean delivery.Biochemical mediators that were detected included IL-1β, IL-2, IL-4, IL-6, IL-7, IL-8, IL-10, IL-12, IL-13, IL-17, TNFα, INFγ, G-CSF, GM-CSF,MCP-1 and MIP-1β, nerve growth factor (NGF), prostaglandin E2 (PG-E2) and substance P. We found no correlations between wound and serum cytokines concentrations or time-release profiles (J Pain. 2008 Jul 9(7):650-7). This article describes and demonstrates the feasibility of collecting and assaying nociceptive and inflammatory mediators in surgical wounds at specific time points. The lack of significant correlations between serum and wound levels shows the importance of determining site-specific release if surgical wounds and localized pathologies are to be studied [corrected].
Development of an on-line scintillation flow-cell detection system with pulse shape discrimination for quantification of actinides (1995)

A flow-cell detection system was developed utilizing pulse shape discrimination as a means of reducing the beta (gamma-ray) background when quantifying alpha emitters. Flow-cells consisting of 63-90 /spl mu/m particles of CaF/sub 2/:Eu, scintillating glass (GS-20), and BaF/sub 2/ were each packed into translucent Teflon tubing. CaF/sub 2/:Eu and GS-20 exhibited only marginal pulse shape resolution, achieving figures of merit, (FOM) of 0.46 and 0.27, respectively. BaF/sub 2/ exhibited reasonable pulse shape resolution, FOM=0.75. Unfortunately, the presence of intrinsic alpha emitters in CaF/sub 2/:Eu and BaF/sub 2/ resulted in an elevated background count rate in the alpha window. Coupled with a detection efficiency of /spl sim/50% for /sup 233/U (E/sub /spl alpha//=4.8 MeV) alpha particles, minimum detectable activities at the optimal pulse shape time discriminator setting were 0.6 Bq for CaFa/sub 2/:Eu and BaF/sub 2/ and 1.1 Bq for GS-20.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Achievement of a synergistic adjuvant effect on arthritis induction by activation of innate immunity and forcing the immune response toward the Th1 phenotype (2004)

DDA, which was first used in autoimmune models, is a potent nonirritant adjuvant, which eliminates all undesired side effects of the Freund's adjuvants. DDA exerts a strong stimulatory effect via the activation of nonspecific (innate) immunity and forces the immune regulation toward Th1 dominance. These lines of evidence also suggest the possibility that seemingly innocuous compounds may exert an adjuvant effect in humans and may create the pathophysiologic basis of autoimmunity in susceptible individuals via the activation/stimulation of innate immunity.
Collagen: Structural Studies Based on the Cleavage of Methionyl Bonds (1965)

Eighteen peptides from the alpha1 fraction and eight from the alpha2 fraction of rat skin collagen cleaved with cyanogen bromide have been identified by chromatography on carboxymethyl cellulose. The isolated peptides show wide differences in amino acid composition, and their molecular weights vary from several thousand to about 23,000. The data indicate that there are two different chains in the alpha1 fraction, demonstrating the nonidentity of all three alpha-chains. The primary structure of each chain appears to be unique throughout its length.
Statistical–mechanical, Molecular Theory of Boundary Conditions for Liquid Flow at Nanostructured Surfaces and in Confined Geometries (2012)

Peer reviewed: Yes
A Novel Space-Frequency Coding Scheme for Single Carrier Modulations (2007)

Single-carrier frequency division multiple access (SC-FDMA) has been adopted as a possible air interface for future wireless networks. It combines most of the advantages of orthogonal frequency division multiple access and the low peak to average power ratio (PAPR) of single carrier (SC) transmission. Existing transmit antenna diversity techniques such as space-time block coding and space-frequency block coding are incompatible either with the system constraints or with the SC nature of SC-FDMA. We propose a novel space-frequency flexible coding scheme compatible with SC-FDMA and we prove its good performance both in terms of PAPR and bit error rate (BER) on frequency selective multiple input multiple output channels.
ChemInform Abstract: Catalytic Asymmetric Hydrogenation of 2,3,5‐Trisubstituted Pyrroles. (2008)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.