gebhart/patrepeval huggingface dataset:
A versatile SPICE model for quantum-well lasers (1997)

A SPICE equivalent-circuit model for the design and analysis of quantum-well lasers is described. The model is based on the three-level rate equations which include, in their characterization of charge dynamics, the role of gateway states at the quantum well. The model is versatile in that it permits both small- and large-signal simulations to be performed. Emphasis here is placed on validating the model via a comparison of simulated results with measured data of the small-signal modulation response, obtained over a wide range of optical output powers from two lasers with different lengths of the separate-confinement heterostructure (SCH). Using a set of tightly specified model parameters, all the important trends in the experimental data are reproduced. The consideration of gateway states is found to be important, with regard to predicting the small-signal response, only for the laser with the longer SCH. This highlights the significance of the interplay between the roles of transport through the SCH and capture/release via the gateway states at the quantum well.
Proton transfer in irradiated L-cysteic acid monohydrate (1974)

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Oct4 Targets Regulatory Nodes to Modulate Stem Cell (2007)

Summary of Oct4 Correlated Genes with Probeset ID,gene symbol, gene name, direction and percentage of correlation,chromosomal location, summary GO category used for Figure 2and GO biological process were listed when known.Found at: doi:10.1371/journal.pone.0000553.s002 (0.28 MBXLS) Table S3 GoStat AnalysisFound at: doi:10.1371/journal.pone.0000553.s003 (0.33 MBXLS) Table S4 Oct4/Sox2 putative binding site analysis with Genesymbol, RefSeq or Ensembl ID, putative binding sequence, andlocation in transcript enumeratedFound at: doi:10.1371/journal.pone.0000553.s004 (0.11 MBXLS) Table S5 Primer sequences for Oct4 target validation by ChIP/QRT-PCRFound at: doi:10.1371/journal.pone.0000553.s005 (0.06 MBDOC) Table S6 Annotation of Oct4 targets.Found at: doi:10.1371/journal.pone.0000553.s006 (0.09 MBDOC) ACKNOWLEDGMENTS The Authors would like to acknowledge the Stem Cell Network for theirsupport of the Stem Cell Genomics Project and the technical staff of theOntario Genomics Innovation Centre for their expert assistance. Kindthanks to Dave Picketts, Marjorie Brand, and Jeff Dilworth for insightfuldiscussions. MAR is an International Scholar of the Howard HughesMedical Institute and holds the Canada Research Chair in MolecularGenetics.
Intracranial subdural haematoma — a rare complication following spinal anaesthesia (1996)

We present a rare case with postspinal headache resulting in an intracranial subdural haematoma. After 5 days of persistant headache the condition was recognized and diagnosed on a computerized tomography-scan (CT) of the skull. The patient was operated with evacuation of the haematoma 2 weeks after the spinal anaesthesia and recovered completely.
Unification of Ernst-equation Backlund transformations using a modified Wahlquist-Estabrook technique; Wahlquist-Estabrook (1983)

The three known Backlund transformations for the Ernst equation are derived using a modification of the Wahlquist-Estabrook prolongation procedure. The modification requires that the equation to be studied be cast into a set of differential forms and their exterior derivatives, such that all coefficients are constant (a "CC ideal''). Analysis of the resulting equations produces 16 solutions composed of the three basic transformations combined with identity and other essentially trivial transformations. The group structure of the transformations is discussed. A Backlund transformation (already known) for the Ernst-Maxwell equations can be found by the same method. Promising generalizations are mentioned.
A Resolution of Reported Discrepancies in the Characteristics of Platelet Glycoproteins IV (GPIV) and III b (GPIII b) (1990)

The terms glycoprotein IV (GPIV) and glycoprotein IIIb (GPIIIb) have been used interchangeably and reports in the literature have indicated this glycoprotein as having a molecular weight variously described as either 88,000 or 97,000, a fast anodal mobility on crossed electrophoresis and either 13 or less than 1 methionine residues on amino acid analysis of the purified glycoprotein. To resolve these discrepancies, we have evaluated the characteristics of GPIV both in whole platelets and after isolation. These studies have shown that the term GPIV defines a protease-resistant platelet surface glycoprotein with Mr 88,330 +/- 2,240 which is immunologically identical with the CD36 differentiation antigen, which migrates with a relatively slow anodal mobility on crossed immunoelectrophoresis and which contains approximately 13 methionine residues per mole.
Pathogenic mycobacteria achieve cellular persistence by inhibiting the Niemann-Pick Type C disease cellular pathway (2017)

These findings provide a novel mechanistic explanation for mycobacterial intracellular persistence, and suggest that targeting interactions between the mycobacteria and host cell pathways may provide a novel avenue for development of anti-TB therapies.
Perspectives in the Solid State Coordination Chemistry of the Molybdenum Oxides (2006)

The chemistry of polyoxomolybdate anions may be exploited in a building block approach to the synthesis of solid state oxide materials. One strategy controls the oxide microstructure by introducing a secondary metal-ligand subunit as a charge-compensating, space-filling and structure-directing component. The resulting organic-inorganic hybrid materials are representative of solid state coordination chemistry in which the oxide microstructure reflects the geometry of the ligand, the coordination preferences of the secondary metal center, and the synergistic interaction of the coordination complex cation with the polyoxomolybdate component.
Puff by Puff Smoking and Individual Puff Analyses / Über zugweises Abrauchen und Pro-Zug-Analysen (1965)

Abstract Our studies showed that the yield of total phenols per cigarette decreases by 55 % when there is an increase in moisture content. This fact is due to the growth of the filtration constant µ
ChemInform Abstract: CHEMISTRY OF SUCCINYLSUCCINIC ACID DERIVATIVES. VI. A SPECIFIC SYNTHESIS OF P‐PHENYLENEDIAMINE (1980)

Abstract Succinylbernsteinsäureester (I) wird mit Aminen (II) in die 2,5‐Di‐ amino‐1,4‐cyclohexadien‐Derivate (III) übergeführt, die mit Brom zu den Aromaten (IV) oxidiert werden.
Anisotropy of Magnetothermal Conductivity in<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mrow><mml:msub><mml:mrow><mml:mi>Sr</mml:mi></mml:mrow><mml:mrow><mml:mn>2</mml:mn></mml:mrow></mml:msub></mml:mrow><mml:mrow><mml:msub><mml:mrow><mml:mi>RuO</mml:mi></mml:mrow><mml:mrow><mml:mn>4</mml:mn></mml:mrow></mml:msub></mml:mrow></mml:math> (2001)

The dependence of in-plane and interplane thermal conductivities of ${\mathrm{Sr}}_{2}{\mathrm{RuO}}_{4}$ on temperature, as well as magnetic field strength and orientation, is reported. We found no notable anisotropy in the thermal conductivity for the magnetic field rotation parallel to the conducting plane in the whole range of experimental temperatures and fields, except in the vicinity of the upper critical field ${H}_{\mathrm{c}2}$, where the anisotropy of the ${H}_{\mathrm{c}2}$ itself plays a dominant role. This finding imposes strong constraints on the possible models of superconductivity in ${\mathrm{Sr}}_{2}{\mathrm{RuO}}_{4}$ and supports the existence of a superconducting gap with a line of nodes running orthogonal to the Fermi surface cylinder.
The role of microRNA‐208a in cardiac hypertrophy induced by aerobic physical training (2013)

The miRNA‐208 regulates gene expression of slow myosin heavy chain(MHC)in heart. We investigated the role of miRNA‐208 and its target Thyroid Hormone Receptor Associated Protein 1 (THRAP1) in aerobic training (AT) induced cardiac hypertrophy (CH). Female Wistar Rats(n=21)into 3 groups: sedentary (S), Trained 1(T1): swimming sessions of 60′, 5 days/week (10 weeks). Trained 2(T2): similar to T1 until 8th week, on the 9th week the rats swan twice/day and on the 10th week 3 times/day. Were assessed: heart rate (HR), blood pressure (BP) by direct measurement, VO2max by ergoespirometry, soleus citrate synthase (CS) activity by spectrophotometer, ventricular function and CH by echocardiography (EGC), CH by LV/BW ratio (mg/g) and cardiomyocyte diameter (CD), gene expression of atrial natriuretic factor (ANF), skeletal α‐actin, α‐MHC and β‐MHC and miR‐208 by Real‐time PCR and protein content of α and β‐MHC and THRAP1 by Western Blott. AT decreased HR and increased VO2max (11%/T1 and 15%/T2) and CS (47%/T1 and 105%/T2). LV/BW ratio increased 13%/T1 and 28%/T2 and CD increased 20%/T1 and 30%/T2. Gene expression of skeletal α‐actin decreased 53%/T2. The E/A ratio increased and isovolumetric relaxation time and myocardial performance index decreased. MiR‐208 expression decreased 62%/T2 with a decrease of β‐MHC and an increase of α‐MHC gene expression(β/‐71%,α/+37%) and protein content(β/−45 % α/+72%) in T2. THRAP1 protein increased 40%/T2 compared with S. APT induced physiological CH and improved diastolic function. MiR‐208a and β‐MHC expression decreased and THRAP‐1 increased. The decrease of miR‐208 was opposite to disease and can be a therapeutic strategy in pathological CH. Support: FAPESP/CAPES/NIH
Long-term sustainability of a worksite canteen intervention of serving more fruit and vegetables (2010)

The present study indicates that sustainability of F&V is possible in worksites where the participatory and empowering approach, self-monitoring, environmental change, dialogue with suppliers and networking among worksite canteens are applied.
Permissible Temporary Occlusion Time in Aneurysm Surgery as Evaluated by Evoked Potential Monitoring (1993)

To clarify the permissible time for temporary vascular occlusion during aneurysm surgery, we have undertaken a retrospective analysis of the results of intraoperative median nerve somatosensory evoked potential (SEP) monitoring in 97 patients with middle cerebral artery (MCA) (46 patients) or internal carotid artery (ICA) (51 patients) aneurysms. All patients underwent temporary vascular occlusion, lasting from 2 to 70 minutes, under the administration of a mixed solution of 20% mannitol with phenytoin and vitamin E. The mean occlusion time was 20.3 minutes for the MCA patients and 15.8 minutes for the ICA patients. The SEP disappeared during occlusion in 42 patients (30 MCA and 12 ICA). All but three eventually recovered the SEP to the baseline level after recirculation, and none of the 39 patients had postoperative sequelae. The time period from the start of occlusion until the complete loss of the SEP averaged 8.6 minutes among these 39 patients, and the occlusion time from total SEP loss until recirculation averaged 12 minutes. In the remaining 3 of the 42 patients (all 3 being ICA aneurysm patients), however, the SEP did not recover after recirculation and all 3 patients showed postoperative sequelae. In two of these three patients, vascular occlusions were performed at the multiple sites (i.e., at the ICA, MCA, anterior cerebral artery, and posterior communicating artery) and the SEP disappeared rapidly after the occlusion.(ABSTRACT TRUNCATED AT 250 WORDS)
Diabetes in the Bio-Breeding/Worcester rat. Induction and acceleration by spleen cell-conditioned media. (1985)

Injections of media conditioned by concanavalin A-activated spleen cells from acutely diabetic rats accelerated the appearance of diabetes in young Bio-Breeding/Worcester (BB/W) rats. Activity was also found in media conditioned by spleen cells from nondiabetic, W-line Wistar Furth and Buffalo rats. Unconditioned media containing mitogen had no activity. Conditioned media also induced diabetes in resistant W-line BB/W rats but not in Wistar Furth rats. A soluble factor may activate a BB lymphocyte population that promotes diabetes.
DNA Base Composition and Esterase Patterns of Bacteria Isolated from Deep Sea Sediments (1969)

Electrophoretic patterns of esterase isozymes and DNA base compositions were determined for 38 marine bacteria, 31 strains of which were from sediment samples collected at depths of 9400–10,400 in in the Philippine and Marianas Trenches of the Pacific Ocean, and 7 from seawater samples collected at various depths of surface–4000 m and from several locations in the Pacific Ocean. Previous numerical taxonomic analysis indicated 5 distinct phenetic clusters; 4 identified as Pseudomonas and 1 as aerogenic Aeromonas. In this study, the DNA base composition range for the entire sample set was found to be 41–59 moles % of GC. However, 32 of the 38 strains possessed a GC of c. 57%. In general, strains belonging to the same phenon possessed nearly identical DNA base composition and demonstrated similar esterase patterns.
Measurement of estrone sulfate in postmenopausal women: comparison of direct RIA and GC-MS/MS methods for monitoring response to endocrine therapy in women with breast cancer. (2007)

We conclude that the direct 'ultrasensitive' RIA for the measurement of serum EIS provides a reliable method for assaying serum concentrations of this estrogen conjugate and should be useful in monitoring the response to endocrine therapy in postmenopausal women with hormone-dependent breast cancer.
ChemInform Abstract: The Use of High‐Solid Loadings in Biomass Pretreatment (2013)

Abstract Review: 66 refs.
E = MC <sup>3</sup> : Error Reduction Equals Motivation Times Communication to the Power of 3 (2012)

This chapter contains sections titled: Defining Medical Errors: Do we Know them When we See Them? The Flip Side Errors that Fly Below the Radar Back to the Index Case Rounding Up Errors Mini-Summary
Consistency analysis for sliding-window visual odometry (2012)

In this paper we focus on the problem of visual odometry, i.e., the task of tracking the pose of a moving platform using visual measurements. In recent years, several VO algorithms have been proposed that employ nonlinear minimization in a sliding window of poses for this task. Through the use of iterative re-linearization, these methods are capable of successfully addressing the nonlinearity of the measurement models, and have become the de-facto standard for high-precision VO. In this work, we conduct an analysis of the properties of marginalization, which is the process through which older states are removed from the sliding window. This analysis shows that the standard way of marginalizing older poses results in an erroneous change in the rank of the measurements' information matrix, and leads to underestimation of the uncertainty of the state estimates. Based on the analytical results, we also propose a simple modification of the way in which the measurement Jacobians are computed. This modification avoids the above problem, and results in an algorithm with superior accuracy, as demonstrated in both simulation tests and real-world experiments.
Magnetic textures in superfluid<sup>3</sup>He B (1975)

Magnetic anisotropy effects have been studied in 3He B with transverse NMR on liquid confined into 0.4 mm wide slits between flat parallel foils. The results have been fitted to recent theories on orientational effects in dynamic magnetism.
The origin of <sup>1</sup>H NMR‐visible triacylglycerol in human neutrophils (2000)

Human neutrophils incubated for 1 h in vitro with 10% commercial pooled, human serum containing high levels of free fatty acids (1141 microM) displayed a distinct lipid signal, typical of triacylglycerol, in the 1H NMR spectrum. Concurrently their plasma membrane triacylglycerol mass increased 4.6-fold with a selective rise in the content of palmitic and linoleic acids. Although qualitatively similar, these effects were much greater than those observed after incubating neutrophils with 50 microg.mL-1 of lipopolysaccharide in the presence of 10% AB serum with normal free fatty acid content (345 microM, LPS/S). Incubation of neutrophils with an artificial mixture of free fatty acids at concentrations found in commercial serum, or with the fatty acid fraction isolated from commercial serum increased the 1H NMR-detectable triacylglycerol. The signal intensity of the 1H NMR-detectable triacylglycerol depended on the triacylglycerol composition, and correlated with increased membrane triacylglycerol mass. Cellular uptake of 3H-labelled palmitic or oleic acids increased in the presence of commercial serum but not with LPS/S, with little contribution in either case to the triacylglycerol pool that increased in mass. Pulse-chase experiments demonstrated that with LPS/S and commercial serum, radiolabelled palmitic acid was preferentially incorporated into triacylglycerol located in the plasma membrane. This process could occur at the plasma membrane, as cytoplasts efficiently convert exogenous fatty acids into triacylglycerol. We propose that LPS/S and serum containing high levels of free fatty acid, important in conditions of sepsis and inflammation, may facilitate the sequestration of palmitic acid into triacylglycerol by different pathways. This triacylglycerol originates from exogenous and endogenous free fatty acids, is 1H NMR-visible, and may have a role in regulating apoptosis.
Reservation Models, From Arequipa to SRP (1998)

We analyse and illustrate two approaches that we have developed for providing reservations to flows. The first approach uses the explicit reservation model: a traffic profile is negotiated between users and the network. ATM and RSVP are two examples for this approach. In this paper we describe our experience in the ACT project EXPERT (AC094) with the explicit reservation model in the context of ATM. We show that the integration of ATM in a TCP/IP oriented operating system is easy and does not require developing applications specially for ATM. The method we have designed is called Arequipa and is described in RFC 2170. It is fully implemented in Linux. However, we are confronted with the complexity required to support a single reservation for each flow. Our analysis is that it is well suited for segregating flows in applications such as private virtual networks, but that, for multimedia networks, the cost of handling a large number of flows is too high. This and other factors led us to develop an alternative solution, based on an implicit reservation model. Our solution is called the Scalable Reservation Protocol (SRP). SRP aggregates flows inside the network: routers other than edge routers performing policing do maintain only aggregate information per port. SRP is being developed and implemented in the framework of the ACTS project DIANA (AC319). Keywords: QoS; Aggregation; Arequipa; ATM; IP; SRP
Panchromatic Light Harvesting and Hot Electron Injection by Ru(II) Dipyrrinates on a TiO<sub>2</sub> Surface (2013)

Three Ru(II) dipyrrinate complexes, [Ru(bpy)2(3-TDP)](PF6) (1), [Ru(H2dcbpy)(Hdcbpy)(3-TDP)] (2), and [Ru(H2dcbpy)(Hdcbpy)(TPADP)] (3) (bpy = 2,2′-bipyridine; dcbpy = 4,4′-dicarboxylato-2,2′-bipyridine; 3-TDP = 3-thienyl-dipyrrinate; TPADP = triphenylamino-dipyrrinate), have been synthesized and characterized by electrochemical and photophysical methods as well as by theoretical electronic structure calculations on the DFT level. The complexes exhibit panchromatic light harvesting due to complementary ligand-based absorption around 450 nm and metal-to-ligand charge transfer (MLCT) absorption around 530 nm. Complexes 2 and 3 have been investigated as potential sensitizers for the dye-sensitized solar cell (DSSC). Time-dependent DFT calculations reveal the preferential localization of an excited-state electron on the H2dcbpy ligands, leading to a favorable scenario for electron injection from these anchoring ligands into TiO2. Solution-phase transient absorption spectroscopy was used to follow the excited state dynamics of methyl-ester derivatives of 2 and 3. Excitation with a 400-nm laser pulse resulted in two bleaches centered at 460 and 540 nm and corresponding to the ligand-based and MLCT transitions, respectively. A rapid 2 ps loss of the ligand based bleach corresponded with a growth of the MLCT bleach that were interpreted as the result of vibrational relaxation between metal-centered and ligand-centered frontier orbitals. The electron-injection kinetics were studied on dyes 2 and 3 anchored on the TiO2 surface. The excited state electron-injection yield and incident photon-to-current efficiency were dramatically suppressed by addition of tert-butylpyridine (TBP), indicating that the lowest excited state was positioned close in energy to the TiO2 acceptor states. Nevertheless, the injection yield measured with 416-nm excitation was less sensitive to the TBP concentration than that measured with 532-nm excitation, thus suggesting the possibility of hot-electron injection from the upper excited states generated by the ligand-based excitations. Based on the findings of this study, a pathway is proposed for improving the electron-injection yield of Ru-dipyrrinate dyes and increasing the power-conversion efficiency of the DSSC incorporating these dyes.
Guidance Cue Netrin-1 and the Regulation of Inflammation in Acute and Chronic Kidney Disease (2014)

Acute kidney injury (AKI) is a common problem in the hospital setting and intensive care unit. Despite improved understanding, there are no effective therapies available to treat AKI. A large body of evidence strongly suggests that ischemia reperfusion injury is an inflammatory disease mediated by both adaptive and innate immune systems. Cell migration also plays an important role in embryonic development and inflammation, and this process is highly regulated to ensure tissue homeostasis. One such paradigm exists in the developing nervous system, where neuronal migration is mediated by a balance between chemoattractive and chemorepulsive signals. The ability of the guidance molecule netrin-1 to repulse or abolish attraction of neuronal cells expressing the UNC5B receptor makes it an attractive candidate for the regulation of inflammatory cell migration. Recent identification of netrin-1 as regulators of immune cell migration has led to a large number of studies looking into how netrin-1 controls inflammation and inflammatory cell migration. This review will focus on recent advances in understanding netrin-1 mediated regulation of inflammation during acute and chronic kidney disease and whether netrin-1 and its receptor activation can be used to treat acute and chronic kidney disease.
Altered expression of urokinase-type plasminogen activator and plasminogen activator inhibitor in high-risk soft tissue sarcomas. (2007)

In recent years, classification of soft-tissue sarcomas (STS) has improved with cytogenetic analyses, but their clinical behavior is still not easily predictable. The aim of this study was to detect alterations in the urokinase-type plasminogen system, involved in tumor growth and invasion, by comparing mRNA levels of its components with those of paired normal tissues, and relating them with patient clinical course. Real-time PCR was performed on human STS cell lines and tissues from highly malignant STS, including leiomyosarcomas and malignant fibrous histiocytomas, to evaluate the expression of urokinase-type plasminogen activator (uPA), uPA receptor (uPAR) and plasminogen activator inhibitor-1 (PAI-1). Immunohistochemistry of gene products was also performed. Median mRNA values of all genes studied were higher in tumors than in paired normal tissues. In agreement with data on STS cell lines, significant up-regulation for uPA and PAI-1 genes compared to reference values was seen. Moreover, different levels of expression were related to histotype and metastatic phenotype. There was accordance between uPA mRNA and protein expression, while immunodetection of PAI-1 product was weak and scattered. Clearly, the controversial role of PAI-1 protein requires further biological analyses, but evident involvement of uPA/PAI-1 gene overexpression in STS malignancy may highlight a molecular defect useful in discriminating STS high-risk patients.