gebhart/patrepeval huggingface dataset:
Expression of Genes Encoding Th1 Cell-Activating Cytokines and Lymphoid Homing Chemokines by Chlamydia-Pulsed Dendritic Cells Correlates with Protective Immunizing Efficacy (2001)

We studied the expression of cytokines, chemokines, and chemokine receptors by the RNase protection assay in chlamydia-pulsed dendritic cells to better understand their potent anti-chlamydial immunizing properties. We found that chlamydia-pulsed dendritic cells express a complex profile of inflammatory and immunomodulatory molecules. These include CCR-7, interleukin-12, and interferon-induced protein 10, molecules that might influence the homing of pulsed dendritic cells to the site of chlamydial infection and the induction of a local protective CD4(+) Th1 cellular immunity.
GWAsimulator: a rapid whole-genome simulation program (2007)

The C++ source code, executables for Linux, Windows and MacOS, manual, example data sets and analysis program are available at http://biostat.mc.vanderbilt.edu/GWAsimulator
Molecular dynamics simulations of sliding friction in a dense granular material (1998)

Friction in a dense two-dimensional granular material is studied by molecular dynamics simulations. Initially the particles are ordered in a triangular lattice where the top layer feels a constant vertical pressure and horizontal velocity field. The dynamics of the material at low velocities is found to be characterized by avalanche-type motion during short time intervals followed by long stationary periods of internal stress buildup. At low external pressures, the time-averaged shear stress is found to be nearly constant for low values of the normal pressure and proportional to the load for higher pressures.
Implementation of Large Neural Networks using Decomposition (2002)

The article presents methods of dealing with huge data in the domain of neural networks. The decomposition of neural networks is introduced and its efficiency is proved by the authors’ experiments. The examinations of the effectiveness of argument reduction in the above filed, are presented. Authors indicate, that decomposition is capable of reducing the size and the complexity of the learned data, and thus it makes the learning process faster or, while dealing with large data, possible. According to the authors experiments, in some cases, argument reduction, makes the learning process harder.
A role for human homologous recombination factors in suppressing microhomology-mediated end joining (2016)

DNA double-strand breaks (DSBs) are toxic lesions, which if improperly repaired can result in cell death or genomic instability. DSB repair is usually facilitated by the classical non-homologous end joining (C-NHEJ), or homologous recombination (HR) pathways. However, a mutagenic alternative NHEJ pathway, microhomology-mediated end joining (MMEJ), can also be deployed. While MMEJ is suppressed by C-NHEJ, the relationship between HR and MMEJ is less clear. Here, we describe a role for HR genes in suppressing MMEJ in human cells. By monitoring DSB mis-repair using a sensitive HPRT assay, we found that depletion of HR proteins, including BRCA2, BRCA1 or RPA, resulted in a distinct mutational signature associated with significant increases in break-induced mutation frequencies, deletion lengths and the annealing of short regions of microhomology (2-6 bp) across the break-site. This signature was dependent on CtIP, MRE11, POLQ and PARP, and thus indicative of MMEJ. In contrast to CtIP or MRE11, depletion of BRCA1 resulted in increased partial resection and MMEJ, thus revealing a functional distinction between these early acting HR factors. Together these findings indicate that HR factors suppress mutagenic MMEJ following DSB resection.
Validation of the RSQS in apparel specialty stores (2011)

Purpose The purpose of this study is to validate the Retail Service Quality Scale (RSQS) developed by Dabholkar et al. in the Malaysian business setting, specifically in the context of apparel specialty stores. Design/methodology/approach Two well‐known retail clothing store chains were selected for this study. Purposive sampling method was used, with a total of 211 responses collected from customers of all X and Y's chain stores in the northern region of Malaysia. Findings The paper finds that all the five dimensions: physical aspects, reliability, personal interaction, problem solving, and policy, are highly suited for measuring retail service quality in clothing stores, also proving that the instrument is applicable in the Malaysian setting. Retail service quality is furthermore associated with future consumption behaviour in terms of the customers' intention to visit, purchase and recommend the stores to others. Research limitations/implications The instrument is proven to be valid, reliable and appropriate for studying retail businesses that offer a mix of services and merchandise. The instrument is also applicable in another culture other than the USA, namely Malaysia. Practical implications Retailers can utilize the instrument for benchmarking current levels of retail service quality, carrying out periodic inspections to measure service performance and improvement, as well as to detect problematic areas of service quality within the stores that are in need of attention. Originality/value This research contributes to the somewhat limited studies carried out on instrument validation in Malaysia. Furthermore, the RSQS is tested in Malaysia – a country with a vibrant, dynamic retail environment and heightened consumer awareness for fashion and retail.
Nephelometric Assay of Immunoglobulin G Chemically Bound to Chloromethyl Styrene Beads (1996)

Monodisperse core–shell stable latexes with reactive methylchloride surface functionalities were prepared at two different reaction temperatures. The reaction temperature played an important role in the amount of reactive functional groups. The covalent coupling had an efficiency of more than 50%. Antibodies covalently bound to functionalized polystyrene beads were used to detect corresponding antigens by nephelometry.
Circadian rhythms in human performance efficiency under free-running conditions. (1985)

A series of four experiments is described in which two men and two women (age range 22-79 years) were allowed to 'free-run' under conditions of isolation from all time cues. The circadian rhythms of performance efficiency were studied for three tasks: serial search, verbal reasoning, and manual dexterity (left and right hand versions). Strong evidence was obtained to suggest that different tasks are under the control of different circadian oscillators. The circadian rhythm in verbal reasoning performance tends to run at a shorter circadian period than that in more simple repetitive tasks, and slight differences in circadian behavior can occur between left- and right-handed dexterity.
CFT: A Cluster-based File Transfer Scheme for highway VANETs (2017)

Effective file transfer between vehicles is fundamental to many emerging vehicular infotainment applications in the highway Vehicular Ad Hoc Networks (VANETs), such as content distribution and social networking. However, due to fast mobility, the connection between vehicles tends to be short-lived and lossy, which makes intact file transfer extremely challenging. To tackle this problem, we presents a novel Cluster-based File Transfer (CFT) scheme for highway VANETs in this paper. With CFT, when a vehicle requests a file, the transmission capacity between the resource vehicle and the destination vehicle is evaluated. If the requested file can be successfully transferred over the direct Vehicular-to-Vehicular (V2V) connection, the file transfer will be completed by the resource and the destination themselves. Otherwise, a cluster will be formed to help the file transfer. As a fully-distributed scheme that relies on the collaboration of cluster members, CFT does not require any assistance from roadside units or access points. Our experimental results indicate that CFT outperforms the existing file transfer schemes for highway VANETs.
IoT Empowered Gesture Recognition System for Life Style Enhancement of Differently Abled People (2018)

Gesture recognition could be effectively used in most instruments targeting the life support of differently abled people. Therefore, an enhanced development was carried out targeting the miscellaneous requirements of the said kind of people. The Kinect capturing device was used to extract the 3-D information and processing could be carried out using a single board PC and the low power blue tooth module was used to get the connectivity between external devices enabling IoT features of the system. Different gestures were carefully identified and unique command set was generated covering each gesture identified. Once the system is configured identifying the relevant conditions of a particular person's hearing conditions, it could be used to address his different hearing requirements.
YASAS - Yet Another Sound Analysis-Synthesis Method (2006)

This paper describes a novel analysis-synthesis method based on estimation and comparison between spectral methods that are specifically designed for modeling of random signals.These methods are an alternative to the discrete Fourier transform, providing high-resolution, smooth and easily interpretable spectral estimation over short signal frames.It is generally acknowledged that musical signals that exhibit both periodicity and variations can be modeled as sinusoidal components with various extents of modulation (generally characterized as band-limited frequency components), and remaining noise or wide-band frequency components that describe unvoiced and other noisy parts of the signal spectrum.Using single frame Fourier analysis makes is difficult to tell if spectral energy at a particular frequency is due to noise or sinusoidal components.Existing methods for such decomposition usually consider properties of Fourier phases, which are noisy.Our method decomposes a signal into sinusoidal, modulated sinusoidal and noise components based on a comparison between two spectral representations, namely autoregressive (AR) and minimum variance distortionless response (MVDR), both calculated from linear prediction coefficients (LPC) in a time varying manner.Using different optimal properties of each model, we develop estimators for frequencies and amplitudes (spectral envelope) of sinusoidal components (spectral lines) in noise and derive a "noisality" index that assigns different weights to contributions of sinusoidal and noise components at every frequency.Examples of synthetic and real sounds are presented in the paper.
The interplay between oxidative stress and brain‐derived neurotrophic factor modulates the outcome of a saturated fat diet on synaptic plasticity and cognition (2004)

A diet high in saturated fat (HF) decreases levels of brain-derived neurotrophic factor (BDNF), to the extent that compromises neuroplasticity and cognitive function, and aggravates the outcome of brain insult. By using the antioxidant power of vitamin E, we performed studies to determine the role of oxidative stress as a mediator for the effects of BDNF on synaptic plasticity and cognition caused by consumption of the HF diet. Male adult rats were maintained on a HF diet for 2 months with or without 500 IU/kg of vitamin E. Supplementation of the HF diet with vitamin E dramatically reduced oxidative damage, normalized levels of BDNF, synapsin I and cyclic AMP-response element-binding protein (CREB), caused by the consumption of the HF diet. In addition, vitamin E supplementation preserved the process of activation of synapsin I and CREB, and reversed the HF-impaired cognitive function. It is known that BDNF facilitates the synapse by modulating synapsin I and CREB, which have been implicated in synaptic plasticity associated to learning and memory. These results show that oxidative stress can interact with the BDNF system to modulate synaptic plasticity and cognitive function. Therefore, studies appear to reveal a mechanism by which events classically related to the maintenance of energy balance of the cell, such as oxidative stress, can interact with molecular events that modulate neuronal and behavioural plasticity.
Analysis of Spatial Disorientation Mishaps in the US Navy (2003)

Spatial disorientation (SD) and subsequent loss of situation awareness (LSA) mishaps for military air forces, commercial aviation, and general aviation have an estimated annual cost in the billions of dollars. SD occurs when the pilot has an incorrect perception of the attitude, altitude, or motion of one's own aircraft relative to the earth or other significant objects. One example of the devastating effects of SD is the following mishap: A US Navy F- 14 Tomcat, shortly after take off, crashed into a residential neighborhood destroying several homes and killing the two aircrew and three people on the ground. Casual factors in the mishap included SD and cockpit distraction. The Naval Aerospace Medical Research Laboratory (NAMRL) has developed an SD mishap analysis tool to support US Navy mishap boards in their investigations, to provide insight into the problem of SD in naval aviation, and to train aviators to avoid SD mishaps. The SD mishap analysis tool uses spatial orientation models and computer animation techniques to produce three-dimensional (3-D) computer simulations of SD mishaps.
The effectiveness of riboflavin and ultraviolet light pathogen reduction technology in eliminating <i>Trypanosoma cruzi</i> from leukoreduced whole blood (2017)

Riboflavin and UV light treatment and leukoreduction used in conjunction appears to eliminate significant amounts of viable T. cruzi in whole blood. Both strategies could complement other blood bank measures already implemented to prevent the transmission of T. cruzi via blood transfusion.
Coupled waveguide antennas (1966)

A structure consisting of two coupled waveguides is proposed as a leaky-wave antenna. The analysis of this device is based on coupled-mode theory. Previous coupled-mode treatments are extended, since radiative loss is not neglected and the asymmetry of the structure is taken into account. Two cases are considered: the coupling parameter constant with distance <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">z</tex> along the antenna and the coupling as a function of <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">z</tex> . In both, the radiative attenuation is maintained constant. It is found that the first case permits two "normal modes" to propagate and, if both modes are excited, the patterns may be superposed to produce desirable overall results. An example is given of an approximation to a pencil beam pattern. By means of the second method, essentially any of the common excitation functions may be produced. An example is given of an antenna to achieve a cosine-on-a-pedestal excitation. Experimental results are given and compared to theory. Suggestions are presented for further work.
Polo-like kinase (Plk) 1 as a target for prostate cancer management (2005)

Prostate cancer (PCa) is the most commonly occurring cancer in American men, next to skin cancer. Existing treatment options and surgical intervention are unable to effectively manage this cancer. Therefore, continuing efforts are ongoing to establish novel mechanism-based targets and strategies for its management. The serine/threonine kinases Polo-like kinase (Plk) 1 plays a key role in mitotic entry of proliferating cells and regulates many aspects of mitosis which are necessary for successful cytokinesis. Plk1 is over-expressed in many tumor types with aberrant elevation frequently constituting a prognostic indicator of poor disease outcome. This review discusses the studies which indicate that Plk1 could be an excellent target for the treatment as well as chemoprevention of prostate cancer.
Refining Visual Meteor Perception Models: Shower Radiant Altitude Effect, Probability Function, and Limiting Magnitude Effect (1999)

We present some preliminary results of current efforts to refine and improve the classical models used for the reduction and analysis of data from visual meteor observers. These include a detailed analysis of the radiant altitude correction factor, K; a refinement to the determination of the visual meteor probability function, P(m); and ongoing steps to produce a more accurate model for the limiting magnitude (LM) correction factor, C. 1 2 THE RADIANT ALTITUDE CORRECTION FACTOR (K) Historical Review of Models: 1 Geometric First Order Approximation (Opik, 1955) V = V0 cos(za) V0 = incident meteor flux V = detected meteor flux za = radiant zenith angle 2 Expanded spherical-cap approximation (Kresak, 1954) a. for za ≤ 80 degrees V = V0 cos(za) b. for za > 80 degrees V = V0 1 2 √ 2 r h + h2 cos(za) + r (1 − sin(za)) + h √ 2 r h + h2 r = Earth radius (mean = 6378 km) h = meteor atmospheric altitude (80–120 km)
ADP-ribosylation factor and coatomer couple fusion to vesicle budding (1994)

The coat proteins required for budding COP-coated vesicles from Golgi membranes, coatomer and ADP-ribosylation factor (ARF) protein, are shown to be required to reconstitute the orderly process of transport between Golgi cisternae in which fusion of transport vesicles begins only after budding ends. When either coat protein is omitted, fusion is uncoupled from budding-donor and acceptor compartments pair directly without an intervening vesicle. Coupling may therefore results from the sequestration of fusogenic membrane proteins into assembling coated vesicles that are only exposed when the coat is removed after budding is complete. This mechanism of coupling explains the phenomenon of "retrograde transport" triggered by uncouplers such as the drug brefeldin A.
<i>Arnica</i> Flowers: Pharmacology, Toxicolgy, and Analysis of the Sesquiterpene Lactones—Their Main Active Substances (1998)

Arnica flowers from the European Compositae Arnica montana have been used in traditional medicine to treat a large variety of different ailments. It has been shown that the known diverse effects of the flowers correlate closely with the pharmacological and toxicological profile of their constituents helenalin, 11α,13-dihydrohelenalin and their esters, which therefore must be considered as their main active compounds. Methods for their qualitative and quantitative determination have been established and the variability in flowers from different geographical origin investigated. Arnica chamissonis ssp. foliosa is used as alternative source for the official "Arnicae flos." In addition to the sesquiterpene lactones of A. montana, they contain 2,3-dihydro- 2α-hydroxy- and 2,3-dihydro-2α-,4α-dihydroxy-helenanolide derivatives. The qualitative and quantitative variation is much larger than in the case of A. montana flowers, but populations exist equal to that of A. montana.
Applying the science of behaviour change to the management of strangles (2021)

The Strangles Symposium in 2019 gathered equine stakeholders from across the industry to discuss the management and prevention of strangles in the UK. The understanding of Streptococcus equi is increasing as is the ability to identify and treat the disease. There is real potential to reduce the incidence of the disease, as highlighted through the guidance produced by experts in 2021. It has been recognised that the preventative measures identified require the behaviour of people across the equine industry to alter. The science of human behaviour change can support the veterinary profession in applying effective, evidence-based interventions to optimise the success of these changes. Pinpointing what behaviours are or are not being performed, and researching what is motivating these behaviours, is key to forming strategies within veterinary practice and at UK policy level, to ensure a targeted and consistent approach is available for people within the equine sector.
Overexpression of<i>FT</i>in cotton affects architecture but not floral organogenesis (2013)

Flowering marks the change from indeterminate to determinate plant growth, and this developmental transition involves the activity of the Arabidopsis FLOWERING LOCUS T (FT) gene product and its orthologs. We demonstrated that when FT is ectopically expressed from a viral vector in cotton, a process referred to as virus induced flowering (VIF), it uncouples flowering from photoperiodic regulation and promotes determinate growth in aerial organs. The accelerated switch to determinate growth affected cotton floral buds and sympodial growth, but did not disrupt floral organogenesis. These results can be interpreted in the context of the balance model, which argues that the balance of indeterminate and determinate growth is influenced by the relative abundance of indeterminate and determinate factors in the growing apices. These results emphasize the expanding role of FT in affecting general determinate growth.
Survey of Network Management Protocols in Wireless Sensor Network (2009)

Wireless sensor networks (WSNs) have promised us a new monitoring and controlling model over the distributed computing environment. Network management in WSNs becomes extremely important and vital in order to keep the whole network and application work properly. This paper summarizes the uniqueness of network management protocol for WSN, provide an overview analysis of several current existed protocols, so as to find out and summarize their advantage and disadvantage, and provide some directions for the future research of network management protocol in WSN.
Elevinflytande - till vems och vilken nytta? (2020)

Elevinflytande ar mangtydigt och larare, elever men aven andra med intresse for utbild­ning och undervisning, har stallt fragan om vad elevinfly­tande ”ar”. Skolans uppdrag som det anges i laro­planen (Skolverket, 2011) lamnar ett handlings­ och tolkningsutrymme att hantera i undervisning. Detta ar en forut­sattning for elevinflytande da det ger en mojlighet till variation och anpassning, samtidigt behover elevinflytande kunna forstas. I den avhandling som jag disputerade med hosten 2019 (Eriksson, 2019), var intresset elevinflytandets granser. Som problemstallning bidrar det med kunskap om teman som didaktik och makt.Elevinflytande handlar om elevers akti­va deltagande och ett utrymme for kritik i undervisning och utbildning dar fragor om demokrati, kunskap och larande halls levande. Skollagen (SFS 2010:800, §4) stipulerar att utbildningen har som syfte att barn och elever ska inhamta och ut­veckla kunskaper och varden, vilket for­tydligas i laroplanen.
PREPARATION AND CHARACTERISATION OF (METH)ACRYLOYLOXYSTARCH (2003)

Abstract By Schotten-Bauman's esterification of starch with (meth)acryloyl chlorides, an ester derivative of starch - (meth)acryloyloxystarch - was prepared, which contains double bonds. The original starch and (meth)acryloyloxystarch were characterised by FTIR, 1 HNMR, 13 C-NMR, GPC and TGA. (Meth)acryloyloxystarch was polymerised in solution by the free-radical process and by photopolymerisation in a solid state to obtain a crosslinked product.
Gait Recognition With Shifted Energy Image and Structural Feature Extraction (2011)

In this paper, we present a novel and efficient gait recognition system. The proposed system uses two novel gait representations, i.e., the shifted energy image and the gait structural profile, which have increased robustness to some classes of structural variations. Furthermore, we introduce a novel method for the simulation of walking conditions and the generation of artificial subjects that are used for the application of linear discriminant analysis. In the decision stage, the two representations are fused. Thorough experimental evaluation, conducted using one traditional and two new databases, demonstrates the advantages of the proposed system in comparison with current state-of-the-art systems.