gebhart/patrepeval huggingface dataset:
Unique Single-Atom Binding of Pseudohalogeno Ligands to Four Metal Ions Induced by Their Trapping into High-Nuclearity Cages This work was supported by CICYT (Grant BP96/0163) and the Research Committee of the University of Patras (C. Caratheodory Programme, No 1941). (2001)

μ<sub>4</sub> end-on coordination (through the N atom) of the pseudohalogeno ligands X<sup>-</sup> =N<sub>3</sub><sup>-</sup> and NCO<sup>-</sup> has been observed in the isostructural nonanuclear Co<sup>II</sup> cages with the general formula [Co<sub>9</sub> {(2-C<sub>5</sub> H<sub>4</sub> N)<sub>2</sub> CO<sub>2</sub> }<sub>4</sub> (O<sub>2</sub> CMe)<sub>8</sub> X<sub>2</sub> ]; this mode is imposed by the trapping of anions X<sup>-</sup> into cavities formed inside the cage. The change of X<sup>-</sup> modulates the magnetic behavior of the cage from antiferromagnetic coupling to a ferrimagnetic high-spin ground state.
Genomic epidemiologic assessment implicates prolonged silent carriage, virulence factors and transmission between staff and patients in a NICU outbreak of MRSA (2021)

ABSTRACT Introduction Methicillin-resistant Staphylococcus aureus (MRSA) is an important pathogen in neonatal intensive care units (NICU) that carries significant morbidity and mortality. Improving our understanding of MRSA transmission dynamics, especially among high risk patients, is an infection prevention priority. Methods We investigated a cluster of clinical MRSA cases in the NICU using a combination of epidemiologic review and whole genome sequencing (WGS) of isolates from clinical and surveillance cultures obtained from patients and healthcare personnel (HCP). Results Phylogenetic analysis identified two genetically distinct phylogenetic clades and revealed multiple silent transmission events between HCP and infants. The predominant outbreak strain harbored multiple virulence factors. Epidemiologic investigation and genomic analysis identified a HCP colonized with the dominant MRSA outbreak strain who cared for the majority of NICU patients who were infected or colonized with the same strain, including one NICU patient with severe infection seven months before the described outbreak. These results guided implementation of infection prevention interventions that prevented further transmission events. Conclusion Silent transmission of MRSA between HCP and NICU patients likely contributed to a NICU outbreak involving a virulent MRSA strain. WGS enabled data-driven decision making to inform implementation of infection control policies that mitigated the outbreak. Prospective WGS coupled with epidemiologic analysis can be used to detect transmission events and prompt early implementation of control strategies. Summary Whole genome sequencing identified a NICU outbreak of MRSA preceded by silent transmission between health care personnel and patients seven months prior to outbreak detection. This study suggests prospective genomic analysis may identify isolates with high virulence potential, offering an early opportunity for intervention.
Scaling‐up distillation efficiencies (1986)

Abstract This paper describes a study of the possibility of using point efficiencies, measured in a small laboratory column, in the scale‐up of distillation efficiencies. The conditions on a large rectangular tray were closely duplicated in a small glass Oldershaw column with one sieve tray having similar hole size and percent free area. Point efficiencies on the large rectangular sieve tray were deduced from the composition profiles and compared with the point efficiencies measured in the small column. A simple relationship between the two columns was found in terms of the froth heights and liquid holdups. The results demonstrate that the slightly lower point efficiencies measured in the Oldershaw column could be used in conjunction with a mathematical mass transfer model based on the eddy diffusion concept, to relate the point efficiencies to the tray efficiences, resulting in a conservative design provided either that allowance is made for other factors, such as nonuniform flow patterns and stagnant zones, or that these are eliminated. A wide range of composition was covered using the two systems MeOH‐nPrOH and EtOH‐nPrOH operating in the froth region.
Specific Activity of Brain Palmitoyl‐CoA Pool Provides Rates of Incorporation of Palmitate in Brain Phospholipids in Awake Rats (1995)

In vivo rates of palmitate incorporation into brain phospholipids were measured in awake rats following programmed intravenous infusion of unesterified [9,10-3H]palmitate to maintain constant plasma specific activity. Animals were killed after 2-10 min of infusion by microwave irradiation and analyzed for tracer distribution in brain phospholipid and phospholipid precursor, i.e., brain unesterified palmitate and palmitoyl-CoA, pools. [9,10-3H]Palmitate incorporation into brain phospholipids was linear with time and rapid, with > 50% of brain tracer in choline-containing glycerophospholipids at 2 min of infusion. However, tracer specific activity in brain phospholipid precursor pools was low and averaged only 1.6-1.8% of plasma unesterified palmitate specific activity. Correction for brain palmitoyl-CoA specific activity increased the calculated rate of palmitate incorporation into brain phospholipids (0.52 nmol/s/g) by approximately 60-fold. The results suggest that palmitate incorporation and turnover in brain phospholipids are far more rapid than generally assumed and that this rapid turnover dilutes tracer specific activity in brain palmitoyl-CoA pool owing to release and recycling of unlabeled fatty acid from phospholipid breakdown.
HPV-related squamous cell carcinoma of the anal canal with papillary features. (2013)

Human papilloma virus (HPV)-related squamous cell carcinoma involving the anal canal is a carcinoma associated with high-risk types of HPV. HPV-related squamous cell carcinoma with papillary morphology (papillary squamous cell carcinoma) has been described in the oropharynx, specially the tonsil. Histologically, an anal papillary HPV-related squamous cell …
Sensitivity analysis of iterative design processes (1996)

As design processes continue to increase in complexity, it is important to base process improvements on quantitative analysis. In this paper we develop an analytical approach to analyze sequential design processes using sensitivity analysis. Two applications illustrate this approach, one involving a Pareto analysis of an ASIC design process and the other an optimization of a software design process to determine the lower bound of the process completion time.
In Vitro Fermentation by Human Fecal Microflora of Wheat Arabinoxylans (2007)

The fermentation of three arabinoxylan (AX) fractions from wheat by the human fecal microflora was investigated in vitro. Three AX fractions, with average molecular masses of 354, 278, and 66 kDa, were incorporated into miniature-scale batch cultures (with inulin as a positive prebiotic control) with feces from three healthy donors, aged 23-29. Microflora changes were monitored by the culture-independent technique, fluorescent in situ hybridization, and short chain fatty acid (SCFA) and lactic acid production were measured by high-performance liquid chromatography. Total cell numbers increased significantly in all treated cultures, and the fermentation of AX was associated with a proliferation of the bifidobacteria, lactobacilli, and eubacteria groups. Smaller but statistically significant increases in bacteroides and clostridia groups were also observed. All AX fractions had comparable bifidogenic impacts on the microflora at 5 and 12 h, but the 66 kDa AX was particularly selective for lactobacilli. Eubacteria increased significantly on all AX fractions, particularly on 66 kDa AX. As previously reported, inulin gave a selective increase in bifidobacteria. All supplemented cultures showed significant rises in total SCFA production, with a particularly high proportion of butyric acid being produced from AX fermentation. The prebiotic effect, that is, the selectivity of AX for bifidobacteria and lactobacilli groups, increased as the molecular mass of the AX decreased. This suggests that molecular mass may influence the fermentation of AX in the colon.
The Added Diagnostic Value of Liquid Gastric Emptying Compared with Solid Emptying Alone (2009)

For the detection of gastroparesis, a 30-min study of clear liquid gastric-emptying has considerable added diagnostic value over a study of solid emptying alone.
Experimental Evidence for the Involvement of PDLIM5 in Mood Disorders in Hetero Knockout Mice (2013)

These findings are partially compatible with reported observations in humans, indicating that PDLIM5 is involved in psychiatric disorders, including mood disorders.
Preliminary evaluation of the VOYAGER spoken language system (1989)

VOYAGER is a speech understanding system currently under development at MIT. It provides information and navigational assistance for a geographical area within the city of Cambridge, Massachusetts. Recently, we have completed the initial implementation of the system. This paper describes the preliminary evaluation of VOYAGER, using a spontaneous speech database that was also recently collected.
Ultrafast operation of heterostructure bipolar transistors resulting from coherent base transport of minority carriers (2002)

The author has discussed coherent base propagation effects that can be obtained in stepwise graded and linearly graded bandgap base structures of heterostructure bipolar transistors. These effects open up one or several bands of frequencies above f/sub T/, where the transistor is active. Physically, the active behavior of a coherent transistor results from the phaseshift between the collector current and voltage, acquired during the minority-carrier transit across the base.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Insertional Mutagenesis of the Mouse Germline With Sleeping Beauty Transposition (2008)

Efficient linking of primary DNA sequence information to gene functions in vertebrate models requires that genetic modifications and their effects are analyzed in an efficacious, controlled, and scalable manner. Thus, to facilitate analysis of gene function, new genetic tools and strategies are currently under development. Transposable elements, by virtue of their inherent ability to insert into DNA, can be developed into useful tools for chromosomal manipulations. Mutagenesis screens based on transposable elements have numerous advantages as they can be applied in vivo and are therefore phenotype-driven, and molecular analysis of the mutations is straightforward. Current progress in this field indicates that transposable elements will serve as indispensable tools in the genetic toolkit of vertebrate models. Here, we provide experimental protocols for the construction, functional testing, and application of the Sleeping Beauty transposon for insertional mutagenesis of the mouse germline.
Investigation of Diastereoselective Tandem Ring Closing Metathesis Reactions Toward the Synthesis of Functionalised Spirocyclic Piperidines (2004)

The stereoselective synthesis of a spiropiperidine through a diastereoselective tandem ring closing metathesis (RCM) reaction is reported. The efficient relay of stereochemistry from a pentyl chain to the newly formed spirocentre three carbon atoms away was found to be particularly dependant on the nature of the Ru-catalyst employed - 1st generation Grubbs catalyst was found to be significantly more selective than the more active 2nd generation carbene complexes.
Lectin probe analysis of the glycosylation of human parotid salivary glycoproteins (1995)

Conference Article| November 01 1995 Lectin probe analysis of the glycosylation of human parotid salivary glycoproteins G.H. CARPENTER; G.H. CARPENTER 1Secretory & Soft Tiss. Res. Unit, Dept of Oral Pathology, King's College School of Medicine & Dentistry, London SE5 9NU, U.K. Search for other works by this author on: This Site PubMed Google Scholar G.B. PROCTOR; G.B. PROCTOR 1Secretory & Soft Tiss. Res. Unit, Dept of Oral Pathology, King's College School of Medicine & Dentistry, London SE5 9NU, U.K. Search for other works by this author on: This Site PubMed Google Scholar C.L. PANKHURST; C.L. PANKHURST 1Secretory & Soft Tiss. Res. Unit, Dept of Oral Pathology, King's College School of Medicine & Dentistry, London SE5 9NU, U.K. Search for other works by this author on: This Site PubMed Google Scholar X.S. ZHANG; X.S. ZHANG 1Secretory & Soft Tiss. Res. Unit, Dept of Oral Pathology, King's College School of Medicine & Dentistry, London SE5 9NU, U.K. Search for other works by this author on: This Site PubMed Google Scholar D.K. SHORI D.K. SHORI 1Secretory & Soft Tiss. Res. Unit, Dept of Oral Pathology, King's College School of Medicine & Dentistry, London SE5 9NU, U.K. Search for other works by this author on: This Site PubMed Google Scholar Biochem Soc Trans (1995) 23 (4): 538S. https://doi.org/10.1042/bst023538s Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn MailTo Cite Icon Cite Get Permissions Citation G.H. CARPENTER, G.B. PROCTOR, C.L. PANKHURST, X.S. ZHANG, D.K. SHORI; Lectin probe analysis of the glycosylation of human parotid salivary glycoproteins. Biochem Soc Trans 1 November 1995; 23 (4): 538S. doi: https://doi.org/10.1042/bst023538s Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsBiochemical Society Transactions Search Advanced Search This content is only available as a PDF. © 1995 Biochemical Society1995 Article PDF first page preview Close Modal You do not currently have access to this content.
EVIDENCE FOR QUADRIVALENT CURIUM: X-RAY DATA ON CURIUM OXIDES<sup>1</sup> (1955)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTEVIDENCE FOR QUADRIVALENT CURIUM: X-RAY DATA ON CURIUM OXIDES1L. B. Asprey, F. H. Ellinger, S. Fried, and W. H. ZachariasenCite this: J. Am. Chem. Soc. 1955, 77, 6, 1707–1708Publication Date (Print):March 1, 1955Publication History Published online1 May 2002Published inissue 1 March 1955https://doi.org/10.1021/ja01611a108RIGHTS & PERMISSIONSArticle Views149Altmetric-Citations78LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (247 KB) Get e-Alerts Get e-Alerts
Quantitative Image Analysis of Laminin Immunoreactivity in Skin Basement Membrane Irradiated with 1 GeV/nucleon Iron Particles (2000)

We previously reported that laminin immunoreactivity in mouse mammary epithelium is altered shortly after whole-body irradiation with 0.8 Gy from 600 MeV/nucleon iron ions but is unaffected after exposure to sparsely ionizing radiation. This observation led us to propose that the effect could be due to protein damage from the high ionization density of the ion tracks. If so, we predicted that it would be evident soon after radiation exposure in basement membranes of other tissues and would depend on ion fluence. To test this hypothesis, we used immunofluorescence, confocal laser scanning microscopy, and image segmentation techniques to quantify changes in the basement membrane of mouse skin epidermis. At 1 h after exposure to 1 GeV/nucleon iron ions with doses from 0.03 to 1.6 Gy, neither the visual appearance nor the mean pixel intensity of laminin in the basement membrane of mouse dorsal skin epidermis was altered compared to sham-irradiated tissue. This result does not support the hypothesis that particle traversal directly affects laminin protein integrity. However, the mean pixel intensity of laminin immunoreactivity was significantly decreased in epidermal basement membrane at 48 and 96 h after exposure to 0.8 Gy 1 GeV/nucleon iron ions. We confirmed this effect with two additional antibodies raised against affinity-purified laminin 1 and the E3 fragment of the long-arm of laminin 1. In contrast, collagen type IV, another component of the basement membrane, was unaffected. Our studies demonstrate quantitatively that densely ionizing radiation elicits changes in skin microenvironments distinct from those induced by sparsely ionizing radiation. Such effects may might contribute to the carcinogenic potential of densely ionizing radiation by altering cellular signaling cascades mediated by cell-extracellular matrix interactions.
Exploration and Practice of the 211 Mode of Talent Cultivation in Regional University (2011)

Through analyzing the problems existed in the mode of talent cultivation of computer major in regional university,presents a new 211 mode of talent cultivation,establishes the curriculum system which can meet the social requirements and the multi -dimensional practice teaching syste.The mode of construction can cultivate versatile and practical talents with good foundation and wide knowledge and will improve students' professional qualities and practical abilities.
An End-to-End Approach to Developing Biological and Chemical Detector Requirements. (2016)

Abstract not provided.
Sonderätzverfahren für Stähle mit Anwendungsbeispielen (1963)

Anwendung und Weiterentwicklung von zwei Ätzverfahren: 1. der Thiosulfatätzung nach H. Klemm sowie 2. der Austenitkorngrenzenätzung nach S. Béchet und L. Beaujard. Vorteile der Thiosulfatätzung beim Nachweis von Gefügebestandteilen und Seigerungen. Verbesserung des Ätzverfahrens zur Sichtbarmachung der Austenitkorngrenzen in anlaßzähen und anlaßspröden, vergüteten Stählen. Beurteilung von Werkstofftrennungen nach der Spannungskorrosion und nach dem Härten unter Berücksichtigung der Austenitkorngrenzen.
Investigation into damaged gear of off-road motorcycles (2020)

If failure occurs in gear wheels in a racer motorcycle gearbox, the possible causes are manifold: inadequate material, improper care (poor lubrication, incorrect assembly) or inadequate thermochemical treatment procedure. This investigation focused on spur wheels of chromium-nickel Czech Standard (ÄSN) 16720 steel containing 0.18 % C, 0.4 % Mn, 1.5 % Cr, 4.25 % Ni and 1 % W. The steel had been quenched to 60-62 HRC and the case hardening depth was 0.8 mm. The client requested that these wheels have a life of 100 hours. The failure occurred while the wheels were in operation. The fracture surfaces in the wheels were examined in a scanning electron microscope (SEM). The fracture surfaces were prominent in the failure locations. EDS point analysis in the SEM revealed spots with higher chromium levels on the fracture surfaces. The average size of these spots was several dozen micrometres. The spots were suspected to have caused or contributed to the failure. A hardness profile across one tooth was measured using a microhardness tester. In addition, the thickness of the carburized layer was determined. Quality of the surface was assessed using macrophoto-graphs taken with a low-power stereomicroscope. In addition, metallographic sections were prepared and observed in a scanning electron microscope (SEM) and light microscope.
An affirmative answer to John Locke's question of colour scrambling (2004)

Author(s): Hoffman, Donald D.; Carruthers, Ann K. | Abstract: Is it possible, John Locke pondered in his Essay of 1690, that “the idea that a violet produced in one man's mind by his eyes were the same that a marigold produced in another man's, and vice versa.”?1 Could the colours I experience differ from yours, even if experiments reveal no difference between us? Locke's question is raised by inquisitive children, but remains hotly debated by scientists and philosophers because its answer is key to an unsolved mystery of science: What is the relationship between brain activity and conscious experience?2–8 How, precisely, can brain activity cause, or be, my experience of chartreuse or the fragrance of a rose?9,10 If colour scrambling of the type Locke envisioned is possible, this would notably constrain the empirical search for relationships between brain activity and consciousness. It would entail that conscious experiences could change without concomitant functional changes in brain states. Locke's question has stirred prolific debate through the ensuing centuries, but no mathematical articulation or proof. Here we prove that the answer is “Yes”: colour scrambling is possible without violating scientific laws.
The 8th OOPSLA workshop on domain-specific modeling (2008)

Domain-Specific Modeling raises the level of abstraction beyond programming by specifying the solution directly using visual models to express domain concepts. In many cases, final products can be generated automatically from these high-level specifications. This automation is possible because both the language and generators fit the requirements of only one domain. This paper introduces Domain-Specific Modeling and describes the related 2-day workshop (19th and 20th October).
Non‐invasive transgenic mouse genotyping using stool analysis (1999)

Commonly applied genotyping of transgenic mice involves using tail or ear biopsies which may cause discomfort to the animal. We tested the possibility of polymerase chain reaction (PCR)-based mouse genotyping using stool specimens from three transgenic mouse lines that overexpress 10-18 transgene copies of human keratin polypeptide 18, as compared to genotyping using tail biopsies. Stool specimens were obtained with ease and provided easy detection of the human transgene product. The method was also able to detect endogenous mouse actin and keratin genes which presumably are present at two copies each. Nested PCR was not necessary for genotyping using stool-derived genomic material but did increase the relative magnitude of the signal obtained. The non-invasive genotyping method described herein offers a reproducible, sensitive and effective modality that could replace invasive tissue sampling procedures currently used to test thousands of genetically altered mice.
Philippe PAYEN, Les arrêts de règlement du Parlement de Paris au XVIIIe siècle. Dimension et doctrine, Paris, PUF, Les grandes thèses du droit français, 1997, 526 p. (2003)

Aux yeux de la plupart des lecteurs des A.H.R.F., les arrêts de règlement n'ont sans doute pas bonne réputation, tant leur image incarne la confusion des pouvoirs. N'ont-ils pas été condamnés par la loi des 16-24 août 1790 réorganisant la justice, avant que l'article 5 du Code civil interdise formellement aux juges « de prononcer par voie de disposition générale et réglementaire sur les causes qui leur sont soumises » ? Et si la Constitution de 1958 évoque le « pouvoir réglementaire », c'est ...