gebhart/patrepeval huggingface dataset:
Taxonomic updates for some confusing Micronesian species of Camponotus (Hymenoptera: Formicidae: Formicinae) (2016)

Ronald M. Clouse, Benjamin D. Blanchard, Rebecca Gibson, Ward C. Wheeler, Milan Janda (2016): Taxonomic updates for some confusing Micronesian species of Camponotus (Hymenoptera: Formicidae: Formicinae). Myrmecological News 23: 139-152, DOI: 10.5281/zenodo.164974
Multiple alleles for tuber shape in diploid potato detected by qualitative and quantitative genetic analysis using RFLPs. (1994)

Tuber shape in potato is commonly regarded as displaying continuous variation, yet at the diploid level phenotypes can be discerned visually, having round or long tubers. Inheritance of qualitative tuber shape can be explained by a single locus Ro, round being dominant to long. With restriction fragment length polymorphisms (RFLPs) the Ro locus was mapped on chromosome 10. Tuber shape was also studied as a quantitative trait, using the length/width ratio as trait value. The estimated broad sense heritability was h2 = 0.80. The morphologically mapped Ro locus explained 75% of the genetic variation, indicating the presence of a major quantitative trait locus (QTL) at the Ro locus and minor genetic factors. RFLP alleles linked with Ro alleles were used to divide the progeny into four genotypic classes: RofemaleRomale:Rofemalero:roRomale:roro = 1:1:1:1. The recessive ro allele is identical by descent in both parents. The significantly different effects (P = 0.0157) of the non-identical alleles Rofemale and Romale provided evidence for multiallelism at the Ro locus. Linkage mapping of the Ro locus was compared with QTL mapping. Only those markers which are polymorphic in both parents allow accurate QTL mapping when genetic factors segregate from both parents. This finding applies to QTL mapping in all outbreeders without homozygous inbred strains.
New methodologies for the synthesis of C-2 functionalized hypoxanthine nucleosides (1988)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTNew methodologies for the synthesis of C-2 functionalized hypoxanthine nucleosidesVasu Nair, Gregory A. Turner, Greg S. Buenger, and Stanley D. ChamberlainCite this: J. Org. Chem. 1988, 53, 13, 3051–3057Publication Date (Print):June 1, 1988Publication History Published online1 May 2002Published inissue 1 June 1988https://pubs.acs.org/doi/10.1021/jo00248a027https://doi.org/10.1021/jo00248a027research-articleACS PublicationsRequest reuse permissionsArticle Views961Altmetric-Citations64LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Some physiological and biochemical consequences of psychological postulates. (1968)

Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans the biological, physical, and social sciences.
Intense and specialized dendritic localization of the fragile X mental retardation protein in binaural brainstem neurons: A comparative study in the alligator, chicken, gerbil, and human (2013)

Neuronal dendrites are structurally and functionally dynamic in response to changes in afferent activity. The fragile X mental retardation protein (FMRP) is an mRNA binding protein that regulates activity-dependent protein synthesis and morphological dynamics of dendrites. Loss and abnormal expression of FMRP occur in fragile X syndrome (FXS) and some forms of autism spectrum disorders. To provide further understanding of how FMRP signaling regulates dendritic dynamics, we examined dendritic expression and localization of FMRP in the reptilian and avian nucleus laminaris (NL) and its mammalian analogue, the medial superior olive (MSO), in rodents and humans. NL/MSO neurons are specialized for temporal processing of low-frequency sounds for binaural hearing, which is impaired in FXS. Protein BLAST analyses first demonstrate that the FMRP amino acid sequences in the alligator and chicken are highly similar to human FMRP with identical mRNA-binding and phosphorylation sites, suggesting that FMRP functions similarly across vertebrates. Immunocytochemistry further reveals that NL/MSO neurons have very high levels of dendritic FMRP in low-frequency hearing vertebrates including alligator, chicken, gerbil, and human. Remarkably, dendritic FMRP in NL/MSO neurons often accumulates at branch points and enlarged distal tips, loci known to be critical for branch-specific dendritic arbor dynamics. These observations support an important role for FMRP in regulating dendritic properties of binaural neurons that are essential for low-frequency sound localization and auditory scene segregation, and support the relevance of studying this regulation in nonhuman vertebrates that use low frequencies in order to further understand human auditory processing disorders.
Locality and scheduling in the massively multithreaded era (2015)

Massively parallel processing devices, like Graphics Processing Units (GPUs), have the ability to accelerate highly parallel workloads in an energy-efficient manner. However, executing irregular or less tuned workloads poses performance and energy-efficiency challenges on contemporary GPUs. These inefficiencies come from two primary sources: ineffective management of locality and decreased functional unit utilization. To decrease these effects, GPU programmers are encouraged to restructure their code to fit the underlying hardware architecture which affects the portability of their code and complicates the GPU programming process. This dissertation proposes three novel GPU microarchitecture enhancements for mitigating both the locality and utilization problems on an important class of irregular GPU applications. The first mechanism, Cache-Conscious Warp Scheduling (CCWS), is an adaptive hardware mechanism that makes use of a novel locality detector to capture memory reference locality that is lost by other schedulers due to excessive contention for cache capacity. On cache-sensitive, irregular GPU workloads, CCWS provides a 63% speedup over previous scheduling techniques. This dissertation uses CCWS to demonstrate that improvements to the hardware thread scheduling policy in massively multithreaded systems offer a promising new design space to explore in locality management. The second mechanism, Divergence-Aware Warp Scheduling (DAWS), introduces a divergence-based cache footprint predictor to estimate how much L1 data cache capacity is needed to capture locality in loops. We demonstrate that the predictive, pre-emptive nature of DAWS can provide an additional 26% performance improvement over CCWS. This dissertation also demonstrates that DAWS can effectively shift the burden of locality management from software to hardware by increasing the performance of simpler and more portable code on the GPU. Finally, this dissertation details a Variable Warp-Size Architecture (VWS) which improves the performance of irregular applications by 35%. VWS improves irregular code by using a smaller warp size while maintaining the performance and energy-efficiency of regular code by ganging the execution of these smaller warps together in the warp scheduler.
The effects of callous-unemotional traits and aggression subtypes on amygdala activity in response to negative faces (2020)

Our results showed differences in amygdala activity and SC responses to emotional faces between cases with ODD/CD and TD, while CU traits moderate both central (amygdala) and peripheral (SC) responses. Our insights regarding subtypes and trait-specific aggression could be used for improved diagnostics and personalized treatment.
Towards the synthesis of pyloricidins, synthesis of (2S,3R,4R,5S)-5-amino-2,3,4,6-tetrahydroxyhexanoyl-ß-D-phenyl alanine with differential protective groups (2004)

Highly practical and efficient synthesis of (2S,3R,4R,5S)-5-(tert-butyloxycarbonyl)amino-2,3,4,6-tetrahydroxyhexanoyl--D-phenylalanine methyl ester was achieved using easily available Garner aldehyde and phenylglycine, which is an advanced intermediate for the synthesis of pyloricidins.
Effect of supercritical CO<sub>2</sub>plasticization on the degradation and residual crystallinity of melt-extruded spironolactone (2014)

Immediate-release solid dispersions of a slowly dissolving active pharmaceutical ingredient, spironolactone, were prepared by supercritical-CO2-assisted melt extrusion (a solvent-free and continuous manufacturing technology) using Eudragit E as matrix. Through optimizing process parameters (i.e. temperature, melt throughput, pressure and CO2 flow), stable foams with high porosity, homogeneous structure and thin (even submicronic) walls could be prepared, as revealed by scanning electron microscopy. The samples were found to be rigid enough to mill, enabling further processing, as is necessary to formulate tablets. The influence of extrusion temperature and melt throughput on residual drug crystallinity was measured using non-invasive confocal Raman mapping coupled with chemometric analysis, while the influence on the degree of drug degradation was determined using high performance liquid chromatography. The plasticizing effect of supercritical CO2 was shown to reasonably improve the purity of the prepared solid dispersions by enabling high-yield production at lower temperature ranges. At the same time, shorter residence time and lower temperature slightly increased residual drug crystallinity. The obtained foamy structures ensured immediate drug dissolution in an acidic medium. Copyright © 2014 John Wiley & Sons, Ltd.
Effects of Salicylate and Its Noncalorigenic Congeners on the hyroidal Release of<sup>131</sup>I in Patients with Thyrotoxicosis1 (1964)

In contrast to the findings in a recent report, large doses of salicylate did not consistently slow the thyroidal release of 131I in patients with thyrotoxicosis. In 7 patients who received salicylate, and in 4 tests in which noncalorigenic congeners of salicylate (gentisate and gamma-resorcylate) were administered, slowing of thyroidal release of 131I was observed in only 2, and in both this change was very slight. In the remaining 9 studies, salicylate or its congeners either did not change or appeared to increase thyroidal 131I release rates. Since large therapeutic doses of 131I had been given to the patients in the previous study, it seems possible that the slowing of 131I release observed was due to an inhibition by salicylate of radiation thyroiditis. In all the patients, a decrease in the PBI occurred during the administration of salicylate or its congeners. This decrease could be ascribed largely to the selective inhibition of thyroxine binding by prealbumin which was evident in all the patients during administration of these compounds.
Interaction of Histone Acetylases and Deacetylases In Vivo (2003)

Having opposing enzymatic activities, histone acetylases (HATs) and deacetylases affect chromatin and regulate transcription. The activities of the two enzymes are thought to be balanced in the cell by an unknown mechanism that may involve their direct interaction. Using fluorescence resonance energy transfer analysis, we demonstrated that the acetylase PCAF and histone deacetylase 1 (HDAC1) are in close spatial proximity in living cells, compatible with their physical interaction. In agreement, coimmunoprecipitation assays demonstrated that endogenous HDACs are associated with PCAF and another acetylase, GCN5, in HeLa cells. We found by glycerol gradient sedimentation analysis that HATs are integrated into a large multiprotein HDAC complex that is distinct from the previously described HDAC complexes containing mSin3A, Mi-2/NRD, or CoREST. This HDAC-HAT association is partly accounted for by a direct protein-protein interaction observed in vitro. The HDAC-HAT complex may play a role in establishing a dynamic equilibrium of the two enzymes in vivo.
Scaling up nanoporous graphene membranes (2019)

Practical desalination membranes with nanoporous graphene will need new morphologies
Synthesis and Biological Applications of 2',3'-Dideoxynucleoside-5'-O-(α-thio)Triphosphates (1989)

Abstract Fast and efficient syntheses of 2′,3′-dideoxynucleoside-5′-O-(α-thio)triphosphates (α-S-ddNTP's) starting from 2′-deoxynucleosides are described. They have been used in a modified DNA-sequencing method and were tested as potential inhibitors of HIV-1 reverse transcriptase. An X-ray structure of 3′-deoxythymidine is presented and compared to other known 2′,3′-dideoxynucleoside structures.
Risk Score for In-Hospital Ischemic Stroke Mortality Derived and Validated Within the Get With The Guidelines–Stroke Program (2010)

The Get With the Guidelines-Stroke risk model provides clinicians with a well-validated, practical bedside tool for mortality risk stratification. The NIHSS score provides substantial incremental information on a patient's short-term mortality risk and is the strongest predictor of mortality.
Chelation-Aided Generation of Ketone α,β-Dianions and Their Use as Copper Ate Complexes. Unprecedented Enolate Intervention in the Conjugate Addition to Enones (2000)

ADVERTISEMENT RETURN TO ISSUEPREVCommunicationNEXTChelation-Aided Generation of Ketone α,β-Dianions and Their Use as Copper Ate Complexes. Unprecedented Enolate Intervention in the Conjugate Addition to EnonesIlhyong Ryu, Hiroyuki Nakahira, Masanobu Ikebe, Noboru Sonoda, Shin-ya Yamato, and Mitsuo KomatsuView Author Information Department of Applied Chemistry Graduate School of Engineering, Osaka University Suita, Osaka 565-0871, Japan Cite this: J. Am. Chem. Soc. 2000, 122, 6, 1219–1220Publication Date (Web):January 26, 2000Publication History Received5 October 1999Published online26 January 2000Published inissue 1 February 2000https://pubs.acs.org/doi/10.1021/ja993577thttps://doi.org/10.1021/ja993577trapid-communicationACS PublicationsCopyright © 2000 American Chemical SocietyRequest reuse permissionsArticle Views589Altmetric-Citations37LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information SUBJECTS:Carbonyls,Chemical structure,Enolates,Enones,Ketones Get e-Alerts
A Method for Analyzing Static Performance at Part Load in a Heat Recovery Steam Generator. (1999)

When designing a combined cycle plant, it is essential to estimate performance of the heat recovery steam generator not only at full load but also part load. The method for analyzing the part load performance presented in this paper is based on a full load heat mass balance of the combined cycle plant. Steam turbine inlet pressure, which is the base point of pressure balance, is calculated from a relationship between the pressure ratio and corrected mass flow. Pressure losses of pipes and heat exchangers are corrected by their full load pressure losses. Temperature balance is determined by correcting superheater outlet temperature, pinch point and approach point under the constraints that the area of each heat exchanger is unchangeable. This method is applied to a reheat and triple pressure heat recovery steam generator.
Reaction of 3-formylrifamycin S with secondary amines. (1984)

3-Formylrifamycin S (9) was found to react with secondary aliphatic amines to give 2, 3-dihydropyrimido [4, 5-b] rifamycin derivatives 4, in which the 2'-position was substituted with an alkyl group. When 7-, 8-, and 9-membered alicyclic amines were used, 2, 3-dihydropyrimido [4, 5-b] rifamycin derivatives 5, in which the 1'-and 2'-position were linked with a methylene chain, were obtained. The configuration of the 2'-position in 4 and 5 is discussed. The mechanism of formation of 4 and 5 is also discussed.
Basic characteristics and control method of a new five level inverter with adjustable mid-level voltage (2002)

This paper describes the basic characteristics and PWM control method of a new five-level inverter with adjustable mid-level voltage for adjustable voltage adjustable frequency (AVAF) inverter systems. The strategy is based on a symmetric uniform area sampling PWM technique achieved with a digital signal processor (DSP) and logic circuits. The scheme can decrease that voltage deviation in the output waveform which is caused by the potential variations of the levels, and reduce the switching losses by using two arms modulation. The resulting maximum peak line-to-line voltage is approximately equal to the DC source voltage. The experimental results demonstrate the validity of the proposed method. This paper also illustrates the performance of the proposed inverter in adjusting the magnitude of the mid-level voltage.
La famille des méthodes AK pour l'analyse de fiabilité : synthèse des récentes avancées (2017)

Colloque avec actes et comité de lecture. Internationale.
Probabilistic expression analysis on manifolds (2004)

In this paper, we propose a probabilistic video-based facial expression recognition method on manifolds. The concept of the manifold of facial expression is based on the observation that the images of all possible facial deformations of an individual make a smooth manifold embedded in a high dimensional image space. An enhanced Lipschitz embedding is developed to embed the aligned face appearance in a low dimensional space while keeping the main structure of the manifold. In the embedded space, a complete expression sequence becomes a path on the expression manifold, emanating from a center that corresponds to the neutral expression. Each path consists of several clusters. A probabilistic model of transition between the clusters and paths is learned through training videos in the embedded space. The likelihood of one kind of facial expression is modeled as a mixture density with the clusters as mixture centers. The transition between different expressions is represented as the evolution of the posterior probability of the six basic paths. The experimental results demonstrate that the probabilistic approach can recognize expression transitions effectively. We also synthesize image sequences of changing expressions through the manifold model.
Reactive oxygen metabolite scavengers decrease functional coronary microvascular injury due to ischemia-reperfusion (1991)

The role of reactive oxygen metabolites in ischemia-reperfusion coronary microvascular injury is unclear. To investigate this problem, we tested the effects of the reactive oxygen metabolite scavengers superoxide dismutase (SOD) and dimethylthiourea (DMTU) on ischemia-reperfusion-induced coronary microvascular dysfunction. As an index of vascular function, we assessed microvascular permeability with a double radioisotope protein leak index (PLI) method. Anesthetized dogs underwent 60 min of ischemia via left anterior descending (LAD) occlusion followed by 60 min of reperfusion. Untreated animals (n = 7) received saline. SOD-treated animals (n = 6) received 140 U.kg-1.min-1 (6.6 mg.kg-1.min-1) bovine SOD throughout ischemia and reperfusion. DMTU-treated animals (n = 5) received a 500 mg/kg bolus 30 min before ischemia. At the beginning of reperfusion, radiolabeled autologous protein (113mIn transferrin) and red blood cells (99mTc) were given intravenously for the assessment of permeability. In untreated dogs, ischemia-reperfusion increased the PLI of ischemic (flow less than 20 ml.min-1.100 g-1) myocardium more than threefold compared with that of nonischemic (flow greater than 100 ml.min-1.100 g-1) myocardium (ischemic-to-nonischemic PLI ratio = 3.49 +/- 0.48). SOD reduced the PLI of ischemic myocardium by 45% and DMTU reduced it by 66% (PLI = 9.25 +/- 1.30, 5.04 +/- 1.18, and 3.16 +/- 0.94, untreated, SOD, and DMTU, respectively). The PLI was increased proportional to the regional severity of ischemic blood flow. Both SOD and DMTU reduced the increase in protein leak at all levels of regional ischemic blood flow. Neither SOD nor DMTU increased regional myocardial blood flow to the occluded LAD zone.(ABSTRACT TRUNCATED AT 250 WORDS)
Tissue Cultures and Secondary Metabolites of Centaurium scilloides (1998)

Shoot and callus cultures of Centaurium scilloides (Gentianaceae) were established and the secondary metabolites of the cultures were determined. The major constituents of the shoots cultured on phytohormone free 1/2 MS solid medium were bitter secoiridoid glucosides, swertiamarin (SA) and gentiopicrin (GP). The content of SA in the aerial part was much larger (ca. 6% dry weight) than that in the root portion, although GP content was not so much different in both parts. On the contrary, the major constituent in the callus cultured on 1/2 MS solid medium supplemented with 1.0 mg/l 2,4-D and 0.1 mg/l BA was 3, 5, 6, 7, 8-pentamethoxy-1-O-primeverosylxanthone (PX) and the bitter principles (SA and GP) were produced at very low level. In the time course experiment of the callus cultures, PX showed the maximum content at week 8 of the culture, and the content decreased at the end of the culture period. Callus was also derived from the regenerants which were formed directly on the adventitious roots. The constituents of the callus were similar to those detected in the callus derived from the seedlings. The secondary metabolites as well as the morphology of the regenerants were also similar to those of the seedling plantlets in vitro. These observations showed the stability of the characters in the morphology and secondary metabolism of this plant through some tissue culture stages such as subculture, direct regeneration from the root, etc. Corresponding author: Kazutaka Nishikawa, Faculty of Agriculture, Saga University, Honjo 1, Saga city, Saga 840-8502, Japan