gebhart/patrepeval huggingface dataset:
Finite precision arithmetic and the Schur algorithm (1990)

The numerical behavior of the Schur algorithm under fixed-point arithmetic conditions is investigated. It was found that the variance of the reflection coefficient estimates is large when the autocorrelation coefficients used to obtain the estimates are obtained from a narrowband low-pass signal. This is because such signals yield ill-conditioned autocorrelation matrices and is not due to numerical instability in the Schur algorithm. The effects of quantization errors tend to propagate through the later stages of the reflection coefficient computation in this instance. As a result, the Schur algorithm has numerical properties similar to those of the Durbin algorithm.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Activity guided isolation and characterization of antioxidant and antibacterial agents from some local Nigerian plants (2013)

This study aimed to present the activity guided fractionation, isolation and characterization of antioxidants and antibacterial agents from combined mixture of plants (Vitex doniana, Diospyros mesipiliformis, Acacia polycantha, Pirinari macrophylla, Ficus sycomorus and Parkia biglobosa) and that of Pergularia tomentosa. Combined Mixture of Plants (CMP) is used locally in ratio of 1:1 for the treatment of bacterial infections. The CMP and P. tomentosa were extracted with methanol separately; the residues obtained were also separately suspended in water and successively fractionated with hexane, ethylacetate and n-Butanol. All the fractions obtained were screened for antimicrobial and antioxidant activities. For CMP, only the ethyl acetate fraction (EF) indicated marginal antibacterial activity with 8.0, 7.0 and 7.0 mm zone of inhibition against Micrococcus luteus (MTCC 2470), Bacillus subtilis (MTCC 121) and  Salmonella typhimurium respectively. Minimum inhibitory concentration (MIC) for the CMP was greater than 1000 for M. luteus and S. typhimurium and 87.5 μg/ml for B. subtilis. The CMP fraction was subjected to chromatographic separations which resulted in the isolation and characterization of five bioactive constituents, gallic acid, 3β-OH-α-amyrin, 5,7,3’.4’,5’-pentahydroxy-3-O-glucophyranoside flavones (myricetin 3-O-β-rhamnopyranoside), 5,7,3’,4’ tetrahydroxy-3-O-glucopyranoside flavone (quercetin 3-O-β-rhamnopyranoside) and 3,5,7,3’,4’-pentahydroxy flavones (quercetin). They were characterized with the help of ESI-MS, IR, 1H C13, HMBC/HSQC and COSY-NMR data. These compounds did not show antibacterial activity when tested separately but exhibited appreciable antioxidant activities in different manner. Chromatographic fractionation of hexane extract of P. tomentosa resulted in the isolation of lupeol acetate (LA) with marginal but selective activity against M. luteus and the activity is due to LA rather than the combined constituents. These findings suggest that the fractions of the extracts and pure compounds possess antibacterial and antioxidant properties.   Key words: Antioxidant properties, antibacterial activity, NMR data, Pergularia tomentosa, combined mixture of plants.
Traitement de données dans les groupes de Lie : une approche algébrique. Application au recalage non-linéaire et à l'imagerie du tenseur de diffusion (2006)

Recently, the need for rigorous frameworks for the processing of non-linear data has grown considerably in medical imaging. In this thesis, we propose several general frameworks to process various types of non-linear data, which all belong to Lie groups. To this end, we rely on the algebraic properties of these spaces. Thus, we propose a general processing framework for symmetric and positive-definite matrices, named Log-Euclidean, very simple to use and which has excellent theoretical properties. It is particularly well-adapted to the processing of diffusion tensor MRI. We also propose several frameworks, called polyaffine, to parameterize locally rigid or affine transformations, in a way that guarantees their invertibility. Their use is illustrated in the case of the locally rigid registration of histological slices and of the locally affine 3D registration of MRIs of the human brain. This led us to propose two general frameworks for computing statistics in finite-dimensional Lie groups: first the Log-Euclidean one, which generalizes our work on tensors, and second a framework based on the novel notion of bi-invariant mean, whose properties generalize to Lie groups those of the arithmetic mean. Finally, we generalize our Log-Euclidean framework to diffeomorphic geometrical transformations, which opens the way to a general and consistent framework for statistics in computational anatomy.
Proof of concept for integrating oxy-fuel combustion and the removal of all pollutants from a coal fired flame (2005)

The USDOE/Albany Research Center and Jupiter Oxygen Corporation, working together under a Cooperative Research and Development Agreement, have demonstrated proof-of-concept for the integration of Jupiter’s oxy-fuel combustion and an integrated system for the removal of all stack pollutants, including CO2, from a coal-fired flame. The components were developed using existing process technology with the addition of a new oxy-coal combustion nozzle. The results of the test showed that the system can capture SOx, NOx, particulates, and even mercury as a part of the process of producing liquefied CO2 for sequestration. This is part of an ongoing research project to explore alternative methods for CO2 capture that will be applicable to both retrofit and new plant construction.
Preparation of Functional Monomers as Precursors of Bioprobes from a Common Styrene Derivative and Polymer Synthesis (2018)

CM-Str (4-(Chloromethyl)styrene) was used as a useful starting material for the construction of a series of functional monomers. Substitution of the chlorine to the corresponding azide was performed, and the reduction of the azide proceeded smoothly to afford an aminostyrene, which was used as a common precursor for the preparation of functional monomers. Condensation of the amine with a fluorophore, biotin and carbohydrate was accomplished. Among the monomers, a carbohydrate monomer was polymerized with or without acrylamide as a model polymerization to yield the corresponding water-soluble glycopolymers, and biological evaluations of the glycopolymers for a lectin, and wheat germ agglutinin (WGA), were carried out on the basis of the fluorescence change of tryptophan in the WGA.
Protein kinase C mediates activation of nuclear cAMP response element-binding protein (CREB) in B lymphocytes stimulated through surface Ig. (1995)

Abstract The cAMP response element-binding protein (CREB) is generally considered to be responsive to elevation of cAMP through the activity of protein kinase A (PKA). Although it is well known that cAMP-raising agents can strongly influence B cell stimulation, the regulation of CREB has been little studied. Recently, cross-linking of surface Ig (sIg) was shown to result in trans-activation of a cAMP response element (CRE)-dependent promoter to which bound B cell CREB. In this study, we explored the mechanism underlying this unexpected linkage between sIg and CREB. We found that sIg cross-linking results in phosphorylation of CREB at Ser133. Although this phosphorylation step is mediated by PKA in pheochromocytoma cells, it depends on protein kinase C (PKC) in B lymphocytes. This conclusion is based on abrogation of sIg-induced CREB Ser133 phosphorylation by long-term phorbol-ester treatment to deplete PKC, and mimicking of sIg-induced CREB phosphorylation and CRE-dependent gene expression by short-term PKC agonism. Furthermore, CD40 ligand (CD40L) and LPS, two PKC-independent forms of B cell stimulation, failed to induce phosphorylation of CREB Ser133. These results suggest that CREB responds to specific surface-receptor signals in B cells and that this response is mediated by PKC. Interestingly, forskolin failed to induce phosphorylation of CREB Ser133 in B cells, although it did so in PC12 pheochromocytoma cells. Taken together with PKC mediation of CREB Ser133 phosphorylation in B cells, these results suggest that the dominant mode of CREB regulation is cell-type specific.
Specifying and developing TINA applications with ACE (2002)

The objective of the paper is to present an innovative environment (Application Construction Environment ACE) for the specification, the development and the generation of telecommunication applications according to the TINA and OMG standards. The functionalities offered by the environment are outlined, in addition to experiences of usage of ACE for specification activities.
Multi-wavelengths Photo Magnetic Imaging (2018)

Photo-Magnetic Imaging (PMI) is a novel diffuse optical imaging technique that yields high resolution optical absorption images. It is based on the measurement of the temperature increase of a given medium after its illumination with a near-infrared laser using Magnetic Resonance Thermometry (MRT). In this paper, we present the first multi-wavelengths PMI system able to provide oxy- and deoxyhemoglobin concentration maps with high spatial and quantitative accuracy.
Insulin down-regulates expression of the insulin-responsive glucose transporter (GLUT4) gene: effects on transcription and mRNA turnover. (1993)

Insulin rapidly represses expression of the gene encoding the insulin-responsive glucose transporter (GLUT4) in 3T3-L1 mouse adipocytes. Upon exposure to the hormone the cellular level of GLUT4 mRNA falls (t1/2 approximately 2.5 hr) to 20-30% of its initial level within 10 hr. This is followed by a similar decrease in the level of GLUT4 protein. Down-regulation of GLUT4 mRNA is a result of both rapid repression of transcription of the GLUT4 gene and an increased rate of turnover of the GLUT4 message. As a consequence of prolonged exposure to insulin, 3T3-L1 adipocytes lose their capacity for acute stimulation of hexose uptake by insulin. These findings provide an explanation for the resistance of glucose uptake to insulin in adipose tissue observed in non-insulin-dependent (type 2) diabetes mellitus, particularly that associated with hyperinsulinemia and obesity.
Identification and regulation of 1,25-dihydroxyvitamin D3 receptor activity and biosynthesis of 1,25-dihydroxyvitamin D3. Studies in cultured bovine aortic endothelial cells and human dermal capillaries. (1989)

2D3) has been shown to play roles in both proliferation and differentiation of novel target cells, the potential expression of 1,25(OH)2D3 receptor (VDR) activity was investigated in cultured bovine aortic endothelial cells (BAEC). Receptor binding assays per- formed on nuclear extracts of BAEC revealed a single class of specific, high-affinity VDR that displayed a 4.5-fold increase in maximal ligand binding (Nm.x) in rapidly proliferating BAEC compared with confluent, density-arrested cells. When confluent BAEC were incubated with activators of protein ki- nase C (PKC), N., increased 2.5-fold within 6-24 h and this upregulation was prevented by sphingosine, an inhibitor of PKC, as well as by actinomycin D or cycloheximide. Immunohistochemical visualization using a specific MAb disclosed nuclear localized VDR in venular and capillary endothelial cells of human skin biopsies, documenting the expression of VDR, in vivo, and validating the BAEC model. Finally, additional experiments indicated that BAEC formed the 1,25(OH)2D3 hormonal metabolite from 25(OH)D3 substrate, in vitro, and growth curves of BAEC maintained in the pres- ence of 10-8 M 1,25(OH)2D3 showed a 36% decrease in satura- tion density. These data provide evidence for the presence of a vitamin D microendocrine system in endothelial cells, consist- ing of the VDR and a la-hydroxylase enzyme capable of pro- ducing 1,25(OH)2D3. That both components of this system are coordinately regulated, and that BAEC respond to the 1,25(OH)2D3 hormone by modulating growth kinetics, sug- gests the existence of a vitamin D autocrine loop in endothe- lium that may play a role in the development and/or functions of this pathophysiologically significant cell population.
Cell cycle activation in striatal neurons from Huntington's disease patients and rats treated with 3‐nitropropionic acid (2008)

This study was undertaken to investigate the potential role of cell cycle re-entry in an experimental model of Huntington's disease and in human brain samples. We found that after treatment of rats with the mitochondrial neurotoxin 3-nitropropionic acid, the expression of cell cycle markers of G1 phase measured by immunohistochemistry was induced in the striatal brain region. Furthermore, we detected an increase in the nuclear and also cytoplasmatic E2F-1 expression, suggesting that this protein could activate the apoptotic cascade in rat brain. Western blot analysis of post-mortem brain samples from patients also showed an increase in the expression of E2F-1 and cyclin D1 in comparison with control samples. These results indicate that cell cycle re-entry is activated in Huntington's disease and may contribute to the neurodegenerative process.
The Products of the Cleavage of Triarylbismuth Derivatives by —SH-Containing Compounds<sup>1</sup> (1951)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe Products of the Cleavage of Triarylbismuth Derivatives by —SH-Containing Compounds1Henry Gilman and Harry L. YaleCite this: J. Am. Chem. Soc. 1951, 73, 6, 2880–2881Publication Date (Print):June 1, 1951Publication History Published online1 May 2002Published inissue 1 June 1951https://pubs.acs.org/doi/10.1021/ja01150a134https://doi.org/10.1021/ja01150a134research-articleACS PublicationsRequest reuse permissionsArticle Views177Altmetric-Citations34LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
10-GHz Mode-Locked Ti:Er:LiNb03 Waveguide Laser (1998)

Mode-locked laser operation with a stabilized, packaged and diode-pumped Ti:Er:LiNb03waveguide laser has been demonstrated at 1561-nm (TE) and 1575-nm (TM) wavelength with 14% slope efficiency. Pulse widths of < 10 ps at 10-GHz pulse repetition rate have been measured.
Microbial responses to changes in land use (2011)

Land use change is one of the greatest threats to biodiversity worldwide. This is especially true for land use change that results in the destruction of intact forest, or "deforestation”. Deforestation is causing a loss of biological diversity on an unprecedented scale, especially in the Tropics. It is unclear how the majority of the biodiversity on Earth – microbial biodiversity – is responding to these extraordinary rates of deforestation. I will provide an overview of our current understanding of microbial responses to deforestation. I will focus, as an example, on our current research regarding the effects of deforestation on the diversity of arbuscular mycorrhizal fungi (AMF), bacteria and archaea within Amazon Rainforest soils. This study takes advantage of an established chronosequence of primary rainforest, pastures of various ages, and secondary rainforest to determine the effect of deforestation on the taxonomic, phylogenetic and functional diversity of soil microorganisms, assayed using culture-independent methods. There is increasing evidence that deforestation significantly affects microbial diversity, and that “recovery” of microbial diversity in secondary forest soils is incomplete. For example, rarefaction curves suggest that the accumulation of AMF taxa is higher for Amazon primary forest soil relative to secondary forest soil. In addition, the community composition varies with land use; three AMF taxa were shared between primary and secondary forests, seven were found only in primary forest, and three were found exclusively in secondary forest soil. We also observed that the phylogenetic diversity of AMF is more reduced in secondary forest soils than expected given the regional pool of AMF taxa.*The audio track for talks in this symposium may be obtained at the following web address:**https://sites.google.com/site/esa2010symposium13audiocontent/esa2010-symposium13-audio-content*
Thiol supplementation in aged animals alters antioxidant enzyme activity after heat stress (2005)

Declines in oxidative and thermal stress tolerance are well documented in aging systems. It is thought that these alterations are due in part to reductions in antioxidant defenses. Although intracellular thiols are major redox buffers, their role in maintaining redox homeostasis is not completely understood, particularly during aging, where the reliance on antioxidant enzymes and proteins may be altered. To determine whether thiol supplementation improved the antioxidant enzyme profile of aged animals after heat stress, young and old Fischer 344 rats were treated with N-acetylcysteine (NAC; 4 mmol/kg ip) 2 h before heat stress. Liver tissue was collected before and 0, 30, and 60 min after heat stress. Aging was associated with a significant decline in tissue cysteine and glutathione (GSH) levels. There was also an age-related decrease in copper-zinc superoxide dismutase activity. Heat stress did not alter liver GSH, glutathione disulfide, or antioxidant enzyme activity. With NAC treatment, old animals took up more cysteine than young animals as reflected in an increase in liver GSH and a corresponding decrease in glutamate cysteine ligase activity. Catalase activity increased after NAC treatment in both age groups. Copper-zinc superoxide dismutase activity did not change with heat stress or drug treatment, whereas manganese superoxide dismutase activity was increased in old animals only. These data indicate that GSH synthesis is substrate limited in old animals. Furthermore, aged animals were characterized by large fluctuations in antioxidant enzyme balance after NAC treatment, suggesting a lack of fine control over these enzymes that may leave aged animals susceptible to subsequent stress.
Aircraft Route Optimization for Formation Flight (2014)

We quantify the fuel and cost benefits of applying extended formation flight to commercial airline operations. Central to this study is the development of a bi-level, mixed-integer real formation flight optimization framework. The framework has two main components: 1) a continuous-domain aircraft mission performance optimization and 2) an integer optimization component that selects the best combination of optimized missions to form a formation flight schedule. The mission performance reflects the effects of rolled-up wakes, formation heterogeneity, and formation-induced compressibility. The results show that an airline can use formation flight to reduce fuel burn by 5.8% or direct operating cost by 2.0% in a long-haul international schedule. The savings increase to 7.7% in fuel or 2.6% in cost for a large-scale, transatlantic airline alliance schedule. These results include the effects of a conservative fuel reserve for formation flight. Sensitivity studies show that a modest reduction in the cruise Mach number may be sufficient to manage the impact of formation-induced compressibility effects on system-level formation flight performance. We demonstrate that the potential savings from extended formation flight (an operational improvement using existing aircraft) can approach those claimed for advanced vehicle technologies and unconventional configurations.
Chloroacetyl Chloride (2005)

[79-04-9] C2H2Cl2O (MW 112.94) InChI = 1/C2H2Cl2O/c3-1-2(4)5/h1H2 InChIKey = VGCXGMAHQTYDJK-UHFFFAOYAB (acylating agent;1-34 chlorinating agent;39 a two-carbon building block for cyclization;6, 13, 25-27, 33 a precursor to monochloroketene;35-38) Physical Data: mp −22 °C; bp 105–106 °C; d 1.418 g cm−3. Solubility: soluble in ether, acetone, and methylene chloride. Form Supplied in: liquid; commercially available. Handling, Storage, and Precautions: is corrosive and moisture sensitive. It should be used in an anhydrous atmosphere. Pure ClCH2COCl can be obtained by simple distillation of the commercial product. This reagent should be used in a fume hood.
La mesure du pH au service du lait et des produits laitiers. Applications nouvelles en Allemagne (1937)

mation des types S et R, ainsi que leur rapport à la bàctériophagie.CONCLUSIONS.1°J'ai-constaté dans les colibacilles sensibles étudiés 68,6% .des souches' avec les propriétés biochimiques les caractérisant comme souches fécales.2°Suivant la classification, Bact. coli commune fait 31,4°1<> \ .' .de souches sensibles .: 30 La plus grande fréquence :(100%) de, souches sensibles est' chez les oiseaux et chez les ani ma.ux.i nvertébrés marins.40 La vitesse de développement à 22°et à 37°, ainsi que la vitalité d'une souche se traduisant aussi par la force et la rapidité de fermentation des substances hydrocarbonées sont en raison inverse de sa sensibilité à l'attaque des bactériophages.5°Les souches sensibles étudiées des colibacilles sont caractérisées par une grande constance de leurs propriétés, y compris leur plus ou moins grande résistance à la bactériophagie.BIBLIOGRAPHIE.
Real‐time distortion correction of spiral and echo planar images using the gradient system impulse response function (2015)

This real-time distortion correction framework will enable the use of these high frame rate imaging methods for MRI-guided interventions. Magn Reson Med 75:2278-2285, 2016. © 2015 Wiley Periodicals, Inc.
Minimum cost distributed source coding over a network (2007)

This work considers the problem of transmitting multiple compressible sources over a network at minimum cost. The aim is to find the optimal rates at which the sources should be compressed and the network flows using which they should be transmitted so that the cost of the transmission is minimal. We consider networks with capacity constraints and linear cost functions. The problem is complicated by the fact that the description of the feasible rate region of distributed source coding problems typically has a number of constraints that is exponential in the number of sources. This renders general purpose solvers inefficient. We present a framework in which these problems can be solved efficiently by exploiting the structure of the feasible rate regions coupled with dual decomposition and optimization techniques such as the subgradient method and the proximal bundle method.