gebhart/patrepeval huggingface dataset:
Hepatic Encephalopathy (2009)

This chapter contains sections titled: Hepatic Encephalopathy a Consensus Classification of HE Neuropathology of Hepatic Encephalopathy Pathogenesis of Hepatic Encephalopathy Therapeutic Approaches to HE References
A bio-molecular inspired electronic architecture: bio-based device concepts for enhanced sensing (Invited Paper) (2005)

A biological(bio)-molecular inspired electronic architecture is presented that offers the potential for defining nanoscale sensor platforms with enhanced capabilities for sensing terahertz (THz) frequency bio-signatures. This architecture makes strategic use of integrated biological elements to enable communication and high-level function within densely-packed nanoelectronic systems. In particular, this architecture introduces a new paradigm for establishing hybrid Electro-THz-Optical (ETO) communication channels where the THz-frequency spectral characteristics that are uniquely associated with the embedded bio-molecules are utilized directly. Since the functionality of this architecture is built upon the spectral characteristics of bio-molecules, this immediately allows for defining new methods for enhanced sensing of THz bio-signatures. First, this integrated sensor concept greatly facilitates the collection of THz bio-signatures associated with embedded bio-molecules via interactions with the time-dependent signals propagating through the nanoelectronic circuit. Second, it leads to a new Multi-State Spectral Sensing (MS3) approach where bio-signature information can be collected from multiple metastable state conformations. This paper will also introduce a new class of prototype devices that utilize THz-sensitive bio-molecules to achieve molecular-level sensing and functionality. Here, new simulation results are presented for a class of bio-molecular components that exhibit the prescribed type of ETO characteristics required for realizing integrated sensor platforms. Most noteworthy, this research derives THz spectral bio-signatures for organic molecules that are amenable to photo-induced metastable-state conformations and establishes an initial scientific foundation and design blueprint for an enhanced THz bio-signature sensing capability.
Neue Materialien mit nichtlinearen optischen Eigenschaften durch topotaktische Selbstorganisation zu azentrischen, Chromophore enthaltenden Supergittern (1995)

Bis zu 30mal schneller als bisher gelingt mit dem hier vorgestellten Verfahren der Aufbau von Supergittern, die Chromophore mit nichtlinearen optischen Eigenschaften kovalent verknüpft enthalten und durch hohe Azentrizität, hohes SHG‐Ansprechvermögen und Langzeit‐ sowie Temperaturstabilität gekennzeichnet sind. Rechts ist die im ersten Cyclus erhaltene Schichtstruktur schematisch dargestellt. magnified image
Immunosuppressive Activity of Chemically Synthesized Gangliosides (1995)

New chemical synthetic methods have permitted the synthesis of a spectrum of glycosphingolipid molecular species, some of which are not naturally occurring. Here we have studied a number of chemically synthesized gangliosides for immunosuppressive activity, using a human in vitro specific antigen (tetanus toxoid)-induced assay of the cellular immune response. Chemically synthesized GM3 and GM4 had the same high degree of immunosuppressive activity as did natural GM3 and GM4 gangliosides, verifying that inhibition is intrinsic to the ganglioside molecules and not caused by other molecules sometimes found in natural preparations (e.g., proteins). Studies of modified molecular species of GM3 and GM4, also prepared by chemical synthesis, have shown the influence of certain structural details upon the immunosuppressive activity of gangliosides: (i) the inverse relationship between fatty acyl chain length and immunosuppressive activity is extended to even shorter chain lengths, with the synthetic gangliosides d18:1-C2:0-GM3 and d18:1-C14:0-GM3 being more immunosuppressive than d18:1-C18:0-GM3 and d18:1-C24:0-GM3; (ii) hydroxylation of the fatty acyl group decreases immunosuppressive activity; (iii) substitution of an S-glycosidic bond for an O-glycosidic bond in the sialic acid ketosidic linkage in GM4 does not alter its activity; and (iv) modifications of the sialic acid group variably influence immunosuppressive activity, since KDN-GM3 and -GM4 ganglioside analogues, which contain a 3-deoxy-D-glycero-D-galacto-2-nonulopyranosonic acid in place of N-acetylneuraminic acid, retain activity, while other modifications such as 8-epi-GM3, and to a lesser extent 9-deoxy-GM3, reduce immunosuppressive activity.(ABSTRACT TRUNCATED AT 250 WORDS)
Neutron activation analysis instruction at Pennsylvania State University (1991)

As the oldest continually operating licensed reactor facility in the US, Pennsylvania State University's (Penn State's) research reactor facility has made available radioisotope production and neutron activation analysis (NAA) to university personnel since the mid-1950s. Over the years, an important part of this effort has included instructional programs in the use of NAA. This paper describes these instructional activities and some future plans in this area.
Applications of design for manufacturing : presented at the 1998 ASME International Mechanical Engineering Congress and Exposition, November 15-20, 1998, Anaheim, California (1998)

Comprises nine contributions which explore the tools and methodologies of DFM. The contributions look at methods of design and manufacturing that have to be incorporated to effectively utilize resources and enhance competitiveness in the marketplace. Specific topics include designing machine tools t
LOCALIZATION OF ROSE BENGAL, ALUMINUM PHTHALOCYANINE TETRASULFONATE, AND CHLORIN e6 IN THE RABBIT EYE (2002)

Rose bengal, CASPc, and chlorin e6 accumulate rapidly in the choroid and retinal pigment epithelium and less rapidly in the outer retina. Differences in ocular localization of these photosensitizers were demonstrated. The significance of these findings for potential photodynamic therapy with these agents requires further investigation.
In-Situ Planetary Chemical Analysis (2000)

Both, the search for evidence of life on Mars and the assessment of the Martian environment in respect to its compatibility with human explorers, will require the ability to measure and understand the aqueous chemistry of the Martian regolith. Direct in-situ chemical analysis is the only method by which chemical biosignatures can be reliably recognized and the toxicity of the regolith accurately assessed. Qualitative and quantitative determination of the aqueous ionic constituents and their concentrations is critical in developing kinetic and thermodynamic models that can be used to accurately predict the potential of the past or present Martian geochemical environment to have either generated or still sustain life. In-situ chemical characterization could provide evidence as to whether the chemical composition of the regolith or evaporates in suspected ancient water bodies have been biologically influenced.
GEOBIA Achievements and Spatial Opportunities in the Era of Big Earth Observation Data (2019)

The primary goal of collecting Earth observation (EO) imagery is to map, analyze, and contribute to an understanding of the status and dynamics of geographic phenomena. In geographic information science (GIScience), the term object-based image analysis (OBIA) was tentatively introduced in 2006. When it was re-formulated in 2008 as geographic object-based image analysis (GEOBIA), the primary focus was on integrating multiscale EO data with GIScience and computer vision (CV) solutions to cope with the increasing spatial and temporal resolution of EO imagery. Building on recent trends in the context of big EO data analytics as well as major achievements in CV, the objective of this article is to review the role of spatial concepts in the understanding of image objects as the primary analytical units in semantic EO image analysis, and to identify opportunities where GEOBIA may support multi-source remote sensing analysis in the era of big EO data analytics. We (re-)emphasize the spatial paradigm as a key requisite for an image understanding system capable to deal with and exploit the massive data streams we are currently facing; a system which encompasses a combined physical and statistical model-based inference engine, a well-structured CV system design based on a convergence of spatial and colour evidence, semantic content-based image retrieval capacities, and the full integration of spatio-temporal aspects of the studied geographical phenomena.
Optical Observation of Adiabatic Magnetization in Rare-Earth Compounds (1978)

Anomalous population increase of the first excited state of Dy 3+ in Dy 3 Al 5 O 12 in a pulsed magnetic field of a few ms duration is observed optically at 4.2 K. From experiments of the field and time dependences of the population increase, it is concluded that this phenomenon is due to the adiabatic magnetization of an effective-spin system with a large initial splitting. In deriving this conclusion, it is assumed that, during the pulsed field being applied, the spin system is thermally isolated from the heat reservoir but the spin system is in thermal equilibrium because of a fast effective spin-spin relaxation time. The anomalous population increase is also observed in DyAlO 3 , Er 3 Ga 5 O 12 , Ho 3 Al 5 O 12 , HoAlO 3 , but not in TmAlO 3 .
Conserved Ca2+-antagonist-binding properties and putative folding structure of a recombinant high-affinity dihydropyridine-binding domain (2000)

Sensitivity to 1,4-dihydropyridines (DHPs) can be transferred from L-type (α1C) to non-L-type (α1A) Ca# + channel α1 subunits by the mutation of nine pore-associated non-conserved amino acid residues, yielding mutant α1A DHP .To determine whether the hallmarks of reversible DHP binding to L-type Ca# + channels (nanomolar dissociation constants, stereoselectivity and modulation by other chemical classes of Ca# + antagonist drugs) were maintained in α1A DHP , we analysed the pharmacological properties of (j)-[$H]isradipine-labelled α1A DHP Ca# + channels after heterologous expression.Binding of (j)-isradipine (K i 7.4 nM) and the non-benzoxadiazole DHPs nifedipine (K i 86 nM), (p)nitrendipine (K i 33 nM) and (p)-nimodipine (K i 67 nM) to α1A DHP occurred at low nanomolar K i values.DHP binding was highly stereoselective [25-fold higher affinity for (j)-isradipine].As with native channels it was stimulated by (j)-cis-diltiazem, (j)-tetrandrine and mibefradil.This suggested that the three-
Prevalence of sclerosing cholangitis in adults with autoimmune hepatitis: Evaluating the role of routine magnetic resonance imaging (2008)

The presence of SC detected by MRC and from liver histology in adult patients with AIH may not be clinically overt, and thus the prevalence of this AIH/SC overlap may be higher than previously recognized. Our data suggest that routine radiological evaluation of the biliary tree should be performed in adults given a diagnosis of AIH, as in children the presence of this overlap negatively impacts on survival.
Urothelium update: how the bladder mucosa measures bladder filling (2016)

Normal bladder filling sensation is dependent on multiple interacting mechanoreceptors and signalling pathways. Research efforts need to focus on how these pathways and receptors interact to fully understand normal bladder filling signalling.
[Tumors of the adrenal gland in childhood. Report of 38 patients]. (1984)

During the past 17 years at the Department für Pediatric Surgery, University of Heidelberg, 38 children aged 1.6 to 14 years were adrenalectomized (unilateral 3.3, bilateral 5). Individual diagnoses were: neuroblastoma 23; pheochromocytoma 5; adrenocortical carcinoma 8; adrenocortical adenoma 4; bilateral nodular hyperplasia 2 cases. Patients with histologically benign lesions are alive and without recurrence more than 5 years after surgery, except one patient who developed Nelson's tumor after bilateral adrenalectomy for Cushing's disease. Of the patients with malignant adrenal tumors 21 died within 18 months after therapy was started, a 7 years old girl with an adrenal carcinoma died after a period of 3.6 years of combined treatment. In most cases of adrenocortical tumors virilization was the prominent feature.
Combining Top-Down and Bottom-Up Segmentation (2005)

In this work we show how to combine bottom-up and top-down approaches into a single figure-ground segmentation process. This process provides accurate delineation of object boundaries that cannot be achieved by either the top-down or bottom-up approach alone. The top-down approach uses object representation learned from examples to detect an object in a given input image and provide an approximation to its figure-ground segmentation. The bottom-up approach uses image-based criteria to define coherent groups of pixels that are likely to belong together to either the figure or the background part. The combination provides a final segmentation that draws on the relative merits of both approaches: The result is as close as possible to the top-down approximation, but is also constrained by the bottom-up process to be consistent with significant image discontinuities. We construct a global cost function that represents these top-down and bottom-up requirements. We then show how the global minimum of this function can be efficiently found by applying the sum-product algorithm. This algorithm also provides a confidence map that can be used to identify image regions where additional top-down or bottom-up information may further improve the segmentation. Our experiments show that the results derived from the algorithm are superior to results given by a pure top-down or pure bottom-up approach. The scheme has broad applicability, enabling the combined use of a range of existing bottom-up and top-down segmentations.
METABOLIT BIOAKTIF UTAMA PADA KULTUR JAMUR ENDOFIT AFK-8 YANG DIISOLASI DARI TUMBUHAN AKAR KUNIG ( Arcangelisia flava (L.)Merr)rn( MAIN BIOACTIVE METABOLITE IN THE CULTURE OF ENDOPHYTIC FUNGUS AFK-8 ISOLATED FROM YELLOW WOOD (Arcagelisia Flava (L.)Merr) (2011)

Jamur ednofit AFK-8 yang berasal dari batang tumbuhan akar kuning ( Arcangelisia Flavar (L.)Merr) diisolasi senyawa metabolitnya dan di pelajari aktifiras antibiotikya terhadap beberapa isolat bakteri
DARNet: Deep Active Ray Network for Building Segmentation (2019)

In this paper, we propose a Deep Active Ray Network (DARNet) for automatic building segmentation. Taking an image as input, it first exploits a deep convolutional neural network (CNN) as the backbone to predict energy maps, which are further utilized to construct an energy function. A polygon-based contour is then evolved via minimizing the energy function, of which the minimum defines the final segmentation. Instead of parameterizing the contour using Euclidean coordinates, we adopt polar coordinates, i.e., rays, which not only prevents self-intersection but also simplifies the design of the energy function. Moreover, we propose a loss function that directly encourages the contours to match building boundaries. Our DARNet is trained end-to-end by back-propagating through the energy minimization and the backbone CNN, which makes the CNN adapt to the dynamics of the contour evolution. Experiments on three building instance segmentation datasets demonstrate our DARNet achieves either state-of-the-art or comparable performances to other competitors.
Vibrational and Electronic Absorption Spectroscopy of 2,3-Benzofluorene and Its Cation (2004)

Benzofluorene (C17H12) has been studied in argon matrices via Fourier transform infrared and UV−visible absorption spectroscopy. The analysis of the infrared absorption spectra of neutral and cationic 2,3-benzofluorene was supported by density functional theory (DFT) B3LYP/6-311+G** calculations of the harmonic-mode frequencies. Extensive time-dependent DFT calculations of the electronic vertical excitation energies with BLYP/6-31++G** and B3LYP/6-31++G** functionals/basis sets and the Casida−Salahub asymptotic correction were performed to assign the observed electronic absorption bands of the neutral species. Although the observed low-energy absorption bands are predicted well by theory, the higher-energy bands (Sn ← S0 transitions, n ≥ 4) have been assigned only tentatively. However, the observed electronic absorption bands for the parent, singly dehydrogenated cationic and neutral species are in accord with TDDFT (BLYP/6-31G**) results. The possibility that the 2,3-benzofluorene cation contributes to the unidentified infrared (UIR) bands observed from interstellar space is discussed briefly.
Aufbau eines spieltheoretischen Modells für einen simulativen Vergleich der Koordinationsleistungen verschiedener Verrechnungspreisarten (1998)

Mit dem in diesem Kapitel aufzubauenden Modell soll die Koordinationsleistung verschiedener Verrechnungspreisarten bei einem innerbetrieblichen Sachgütertransfer trotz bestehender sachlicher und personaler Interdependenzen verglichen werden. Maßstab zur Beurteilung ist die First-Best-Koordination aus Sicht der Gesamtunternehmung, d. h., die gesamtoptimale Transfermenge transferiert mit dem gesamtoptimalen Verrechnungspreis. Dieses Koordinationsergebnis kommt nur zustande, wenn die dezentralen Entscheider in vollem Umfang im Sinne der Gesamtunternehmungsziele arbeiten. Gibt es keinen Verrechnungspreis, der diese First-Best-Koordination zu gewährleisten in der Lage ist, soll der Preis mit der geringsten Abweichung von diesem Ergebnis gefunden werden.
Self-assembly and photophysical properties of lanthanide dinuclear triple-helical complexes (1993)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSelf-assembly and photophysical properties of lanthanide dinuclear triple-helical complexesClaude Piguet, Jean Claude G. Buenzli, Gerald Bernardinelli, Gerard Hopfgartner, and Alan F. WilliamsCite this: J. Am. Chem. Soc. 1993, 115, 18, 8197–8206Publication Date (Print):September 1, 1993Publication History Published online1 May 2002Published inissue 1 September 1993https://pubs.acs.org/doi/10.1021/ja00071a032https://doi.org/10.1021/ja00071a032research-articleACS PublicationsRequest reuse permissionsArticle Views1265Altmetric-Citations279LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (2)»Supporting Information Supporting Information Get e-Alerts
Surface roughness in Cu(100)/[Co/Cu]<i>n</i> systems grown by ion-beam sputtering (1996)

The development of surface roughness in Co/Cu systems was investigated through the use of in situ scanning tunneling microscopy. Multilayers and single layers of cobalt and copper were sequentially grown on a Cu(100) substrate. We show that the growth mode of cobalt on copper is quite different from that of copper on cobalt. We characterize these differences by looking at the lateral variations and obtaining a mean measure of island length. The cobalt tends to nucleate in small (&lt;5 nm) islands. An overlayer of copper broadens this length scale while maintaining approximately the same peak-to-peak roughness of 5 monolayers. These growth mechanisms are shown to affect the way in which roughness propagates through multilayers. The impact of deposition temperature is also examined and seen to alter the degree of roughness in these samples. We conclude by discussing the implications for the magnetoresistance of these structures.
Measurement of Ultrasonic Attenuation in Liquid Sodium and Potassium (1963)

The attenuation of sound between 12 and 75 Mc/sec was measured in liquid sodium and liquid potassium from their melting points to 150°C. The measured attenuation in potassium was about 10% in excess of the calculated classical value. No excess absorption was observed in sodium, and an upper limit was placed on a possible excess absorption of about 5% of the classical value.
Inhibition of the interaction of Streptococcus sanguis with hexadecane droplets by 55- and 60-kilodalton hydrophobic proteins of human saliva (1986)

The effect of salivary secretions on the hydrophobicity of Streptococcus sanguis was investigated. Pretreatment of the bacteria with paraffin-stimulated whole saliva resulted in a 79% inhibition of adhesion to hexadecane droplets. Column chromatography on Sepharose 4B and sodium dodecyl sulfate gel electrophoretic analysis indicated that the inhibitory activity of saliva resided in a fraction containing material of approximately 60,000 molecular weight. The active components, which we have termed the hydrophobic components (HC), bind to octyl-Sepharose beads. Pretreatment of S. sanguis with HC resulted in a dose-dependent inhibition of the streptococcus-hexadecane interaction that reached a maximum of 85%. Furthermore, HC effectively blocked the ability of S. sanguis to adhere to hydroxyapatite beads coated with either whole saliva or HC. Sodium dodecyl sulfate-polyacrylamide gel analysis indicated that HC eluted from octyl-Sepharose consisted primarily of two proteins (60 kDa and 55 kilodaltons) which could be resolved by high-pressure liquid chromatography. Both of these proteins were able to inhibit the binding of S. sanguis to hexadecane in a dose-dependent manner; however, the 60-kilodalton molecule was slightly more effective in this assay. Amino acid analysis of these proteins showed that both proteins contained a high percentage of nonpolar amino acids. These findings suggest that certain components of saliva influence the interaction of S. sanguis with hydrophobic surfaces.
The cDNA and deduced amino acid sequence of the γ subunit of the L‐type calcium channel from rabbit skeletal muscle (1990)

Complementary DNAs for the gamma subunit of the calcium channel of rabbit skeletal muscle were isolated on the basis of peptide sequences derived from the purified protein. The deduced primary structure is without homology to other known protein sequences and is consistent with the gamma subunit being an integral membrane protein.
Enantioselective Synthesis of α‐Methyl‐α‐aminocarboxylic Acids by Alkylation of the Lactim Ether of <i>cyclo</i>‐(<scp>L</scp>‐Ala‐<scp>L</scp>‐Ala) (1979)

Preparatively valuable asymmetric amino acid syntheses must be simple to carry out, give yields of >90%, and, where appropriate, permit recovery of the chiral auxiliary agent. These demands are met by the new synthesis via cyclo-(L-Ala-L-Ala).