gebhart/patrepeval huggingface dataset:
Origin of the persistent oscillations of solitary waves in nonlinear quadratic media (1996)

We reveal the origin of the persistent oscillations of solitary waves in a quadratically nonlinear medium. It is found that the oscillations are closely correlated to a nontrivial discrete eigenmode of the corresponding linear eigenvalue problem. In addition to this discrete eigenmode a quasibound mode, weakly coupled to the continuous spectrum, is identified. This gives rise to a long-living beating of the solitary wave amplitude. \textcopyright{} 1996 The American Physical Society.
A Selective Inhibitor of Human C-reactive Protein Translation Is Efficacious In Vitro and in C-reactive Protein Transgenic Mice and Humans (2012)

Observational studies of patients with established rheumatoid arthritis (RA) document a positive correlation between C-reactive protein (CRP) blood concentration and worsening of RA symptoms, but whether this association is causal or not is not known. Using CRP transgenic mice (CRPTg) with collagen-induced arthritis (CIA; a rodent model of RA), we explored causality by testing if CRP lowering via treatment with antisense oligonucleotides (ASOs) targeting human CRP mRNA was efficacious and of clinical benefit. We found that in CRPtg with established CIA, ASO-mediated lowering of blood human CRP levels improved the clinical signs of arthritis. In addition, in healthy human volunteers the ASO was well tolerated and efficacious i.e., treatment achieved significant CRP lowering. ASOs targeting CRP should provide a specific and effective way to lower human CRP levels, which might be an effective therapy in patients with established RA.Molecular Therapy - Nucleic Acids (2012) 1, e52; doi:10.1038/mtna.2012.44; published online 13 November 2012.
Mechanistic Insights into a Supramolecular Self‐Assembling Catalyst System: Evidence for Hydrogen Bonding during Rhodium‐Catalyzed Hydroformylation (2012)

The structural integrity and flexibility provided by intermolecular hydrogen bonds leads to the outstanding properties of the 6-diphenylphosphinopyridin-(2H)-1-one ligand (see scheme) in the rhodium-catalyzed hydroformylation of terminal alkenes, as demonstrated by the combination of spectroscopic methods and DFT computations. Hydrogen bonds were also detected in a competent intermediate of the catalytic cycle.
Peptide Mapping and Assessment of Cryoprotective Activity of 26/27-kDa Dehydrin from Soybean Seeds (2003)

To characterize the molecular weight diversity of seed dehydrin among soybean cultivars, 26/27-kDa soybean dehydrins were purified and compared in peptide mapping patterns, partial amino acid sequences, and cryoprotective activity on enzyme. In reverse phase chromatograms of their trypsin digests, we detected several distinctive peaks, one of which was attributed to a part of the internal glycine-rich region. Partial amino acid sequences of peptide fragments from trypsin and S. aureus V8 protease cleavage were found to be identical to the Mat9 translation. The CP50 of purified 26/27-kDa dehydrins were estimated to be 0.30 and 0.11 microM, respectively.
In vitro activity of the tribactam GV104326 against gram-positive, gram-negative, and anaerobic bacteria (1994)

GV104326 is the first member of a new class of antibiotics (tribactams) selected for development. It combines a particularly broad spectrum (including gram-negative and gram-positive aerobes and anaerobes) with high potency, resistance to beta-lactamases, and complete stability to dehydropeptidases. Comparative MICs were determined for GV104326 against 415 recent clinical isolates (including beta-lactamase producers), using representative antibacterial agents (imipenem, amoxicillin-clavulanic acid, cefpirome, ciprofloxacin, gentamicin, and erythromycin). GV104326 was particularly active against gram-positive bacteria; in general, its in vitro activity was equivalent to that of imipenem, equivalent to or better than that of amoxicillin-clavulanic acid, and superior to that of cefpirome, ciprofloxacin, and erythromycin. Against gram-negative bacteria, GV104326 possessed activity similar to that of imipenem and cefpirome against enterobacteria and Haemophilus spp. but its activity was superior to that of amoxicillin-clavulanic acid. GV104326 showed excellent antianaerobe activity. GV104326 was stable to all clinically relevant beta-lactamases and was rapidly lethal to susceptible bacteria. In Escherichia coli, GV104326 bound predominantly to PBPs 1a and 2 and at low concentrations osmotically stable round forms were observed. GV104326 showed an affinity for PBPs 2 and 4 of Staphylococcus aureus.
Magnetic Shielding Accelerates the Proliferation of Human Neuroblastoma Cell by Promoting G1-Phase Progression (2013)

Organisms have been exposed to the geomagnetic field (GMF) throughout evolutionary history. Exposure to the hypomagnetic field (HMF) by deep magnetic shielding has recently been suggested to have a negative effect on the structure and function of the central nervous system, particularly during early development. Although changes in cell growth and differentiation have been observed in the HMF, the effects of the HMF on cell cycle progression still remain unclear. Here we show that continuous HMF exposure significantly increases the proliferation of human neuroblastoma (SH-SY5Y) cells. The acceleration of proliferation results from a forward shift of the cell cycle in G1-phase. The G2/M-phase progression is not affected in the HMF. Our data is the first to demonstrate that the HMF can stimulate the proliferation of SH-SY5Y cells by promoting cell cycle progression in the G1-phase. This provides a novel way to study the mechanism of cells in response to changes of environmental magnetic field including the GMF.
Simulating vibration-induced electromagnetic fields with Galerkin/least-squares finite element methods (2016)

Research on electrically-small antennas has been active for a long time, but so far it is still challenging to approach the Chu's limit that sets a constraint between the quality factor and the size of an antenna. Some researchers have made efforts to generate electromagnetic (EM) radiation by driving the magnetization of ferri-/ferro-magnetic materials, which can be efficiently realized via mechanical stress in strain-mediated multiferroics. However, very little has been done to accurately model the coupling between elastodynamics and electrodynamics. In this paper, we have derived a coupled weak formulation that utilizes Galerkin finite element method (FEM) for elasticity and least-squares FEM for electromagnetics. After a convergence study is performed, we further apply this framework to simulate the EM fields induced from a shear-mode piezomagnetic resonator.
Prediction of Water Quality in Stratified Reservoirs (1973)

A transient mathematical model which couples the conservation of heat and mass equations is developed and solved numerically. Vertical temperature and concentration profiles within the reservoir and outlet temperature and concentrations for conservative and nonconservative substances are obtained. The results of the predictive model are compared to laboratory measurements of a conservative dye tracer and to field measurements of dissolved oxygen in the Fontana Reservoir during 1 yr of operation. Good results for the laboratory conditions are obtained. Direct comparison with field measurements is limited by the lack of field data on biochemical oxygen demand. However, the trends shown for dissolved oxygen as a function of time are satisfactorily reproduced.
Induction of mammary cancer by 6-nitrochrysene in female CD rats. (1993)

6-Nitrochrysene (6-NC) is a pollutant generated in diesel exhaust. In order to study its propensity to induce mammary cancer, we injected 6-NC into the mammary glands of female CD rats. 4-Nitropyrene (4-NP), the most active mammary carcinogen among the mononitropyrene isomers, was used as a positive control (K. Imaida et al., Cancer Res., 51: 2902-2907, 1991). A total of 2.04 mumol of each compound in dimethyl sulfoxide was injected into each of the six mammary glands on the left side of weanling rats. The corresponding glands on the right side received injections of dimethyl sulfoxide. The thoracic glands were treated on Day 1 and those located in the inguinal area were treated on Day 2. Rats were sacrificed after 43 wk. 6-NC induced fibroadenomas, adenocarcinomas, and spindle cell sarcomas of the mammary glands in a high percentage of the rats. The numbers of animals with mammary tumors and the numbers of malignant tumors were significantly higher in the group treated with 6-NC than in those receiving 4-NP or dimethyl sulfoxide alone. The results of this study, taken together with those of previous bioassays, demonstrate the remarkable activity of 6-NC as a mammary, colon, and lung carcinogen in rodents.
Lithiation Routes to Oxidoles and 2-indolinethiones: Precursors to 2,2'-Dithiobisindoles with Tyrosine Kinase Inhibitory Properties (1994)

N-Substituted oxindoles and 2-indolinethiones can be prepared by lithiation of carboxyl protected N,2-dimethylanilines followed by quenching with CO 2 or CS 2 respectively. 2-Indolinethione derivatives are also available via demethylation of 2-methylthioindoles, which are prepared by lithiation of N-substituted indoles and treatment with dimethyl disulfide
Monoclonal antibodies specific for African swine fever virus proteins (1985)

We have obtained 60 stable hybridomas which produced immunoglobulins that recognized 12 proteins from African swine fever virus particles and African swine fever virus-infected cells. Most of the monoclonal antibodies were specific for the three major structural proteins p150, p72, and p12. The specificity of some monoclonal antibodies for the structural proteins p150 and p37 and the nonstructural proteins p220 and p60 indicated that proteins p150 and p220 are antigenically related to proteins p37 and p60. The association of some viral antigens to specific subcellular components was determined by immunofluorescence and analysis of the binding of monoclonal antibodies to infected cells. A host protein (p24) seemed to be associated with the virus particles.
Effect of Inspiratory Muscle Training on Exercise Tolerance in Asthmatic Individuals (2011)

These data suggest that IMT attenuates inspiratory muscle fatigue, reduces the perception of dyspnea, and increases exercise tolerance. These findings suggest that IMT may be a helpful adjunct to asthma management that has the potential to improve participation and adherence to exercise training in this group. However, the perception of breathlessness is also an important signal of bronchoconstriction, and thus, caution should be exercised if this symptom is abnormally low.
Evaluation des makromolekularen Kontrastmittels P792 für die Kontrastmittel-verstärkte MR Angiographie im Tiermodell bei 3.0T im Vergleich zu 1.5T (2007)

Zielsetzung: Evaluation des intravaskulären Kontrastmittels P792 für die MR Angiographie (MRA) von Kaninchen bei 3.0T im Vergleich zu 1.5T.
MALDI-TOF MS of Phosphorylated Lipids in Biological Fluids Using Immobilized Metal Affinity Chromatography and a Solid Ionic Crystal Matrix (2005)

When targeting a certain class of analytes, such as the phosphorylated lipids in complex biological extracts, interfering species can pose challenges to qualitative and quantitative analyses. Two aspects of lipid analysis were optimized to simplify the isolation and characterization of phosphorylated lipids in biological extracts. A new solid ionic crystal MALDI matrix was synthesized which combined the lipid response enhancing UV-absorber p-nitroaniline with the protonating agent butyric acid. Mass spectra of the extracts containing phosphorylated lipids were simplified by revealing only protonated molecules [M + H]+ of the zwitterionic phosphatidylcholine (PC) headgroup-containing lipids, such as lyso-PC, PC, and platelet-activating factor. For the anionic phosphorylated lipids, such as phosphatidylglycerol, phosphatidic acid, and phosphatidylserine, further spectrum simplification is obtained by the appearance of only the monosodium adducts [M + Na]+ as the major molecular ions, in preference to the double sodium adducts [M + 2Na - H]+. In addition, a new extraction, isolation, and cleanup procedure has been developed to prepare the phosphorylated lipids for MALDI-TOF analysis by the use of immobilized metal ion affinity chromatography media (i.e., ZipTip). The latter procedure was successfully applied to a complex biological tear film lipid layer extract in preparation for MALDI-TOF analysis and phospholipid characterization.
Removal of <i>Cryptosporidium</i> -Sized Polystyrene Microspheres from Swimming Pool Water with a Sand Filter with and without Added Perlite Filter Media (2011)

Waterborne disease outbreaks in U.S. swimming pools have been increasing in recent years, and the majority of the outbreaks are caused by Cryptosporidium oocysts. This research project evaluates sand filtration for swimming pools without and with an amendment, perlite. The evaluation was formed on the basis of removing 5-μm polystyrene microspheres, as a surrogate for Cryptosporidium oocyst, from simulated pool water stored in a 757 L (200 gal) tank. The results showed that a sand filter, without perlite, was not efficient at removing Cryptosporidium-sized particles (i.e., the 5-μm microspheres), with removals averaging 19% (or 0.09 log). The sand filter with a thin layer (1.2 kg/m2 or 0.25 lbs/ft2) of perlite media on top demonstrated removals of 98% (or 1.8 log). The filtration rate was maintained at 49 m/h (20 gpm/ft2) in all experiments. These results indicate that perlite may hold promise in reducing the likelihood of outbreaks of cryptosporidiosis associated with swimming pools.
[Secondary cataract after mechanized extracapsular technic or phacoemulsification]. (1989)

Study of 141 eyes, 30 months after ECCE (35.5%) and after phacoemulsification (64.5%), by a two-handed posterior chamber technic. After 24 months and with IOL, the incidence was 10% with phacoemulsification and 22% with ECCE. This difference was not significative (Pearson's chi 2).
Kinetic Studies on the Formation of Zeolite A (1973)

The influence of temperature, alkalinity, SiO2 source and K+ ions on the formation of zeolite A was investigated. Yield vs. time curves and the corresponding particle size spectra can be described with fairly good approximation by equations for nucleation and crystal growth. Variations in temperature affect nucleation and crystal growth, but alkalinity, SiO2 source, and the content of K+ ions affect nucleation. Coarse crystallites are obtained from low concentrations of batch alkaline solution, by using amorphous silica with a small Carman surface and by adding K+ ions to the mixture. The results can be used to control the nucleation of zeolite types which are normally difficult to prepare.
Data Mining for Improving Manufacturing Processes (2011)

In many modern manufacturing plants, data that characterize the manufacturing process are electronically collected and stored in the organization’s databases. Thus, data mining tools can be used for automatically discovering interesting and useful patterns in the manufacturing processes. These patterns can be subsequently exploited to enhance the whole manufacturing process in such areas as defect prevention and detection, reducing flow-time, increasing safety, etc. When data mining is directed towards improving manufacturing process, there are certain distinctions that should be noted compared to the classical methods employed in quality engineering, such as the experimental design. In data mining the primary purpose of the targeted database is not data analysis; the volume of the collected data makes it impractical to explore it using standard statistical procedures (Braha and Shmilovici, 2003). Request access from your librarian to read this chapter's full text.
Effects of lipoperoxides on proteins in raw and processed peanuts (1975)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTEffects of lipoperoxides on proteins in raw and processed peanutsAllen J. St. Angelo and Robert L. OryCite this: J. Agric. Food Chem. 1975, 23, 2, 141–146Publication Date (Print):March 1, 1975Publication History Published online1 May 2002Published inissue 1 March 1975https://pubs.acs.org/doi/10.1021/jf60198a028https://doi.org/10.1021/jf60198a028research-articleACS PublicationsRequest reuse permissionsArticle Views110Altmetric-Citations33LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
A Low-Power and High-Quality Cordic Based Loeffler DCT (2006)

In this paper, a low-power and high-quality preserving DCT architecture is presented. It is obtained by optimizing the Loeffler DCT based on the Cordic algorithm. The experimental results show that the proposed DCT architecture occupies 19% of the area and consumes about 16% of the power compared to the original Loeffler DCT. Additionally the good transformation quality is retained. In this regard, the proposed Cordic based Loeffler DCT is very suitable for low-power and high-quality CODECs, especially for battery-based systems.
Cryptanalysis of the dual elliptic curve pseudorandom generator (2006)

The Dual Elliptic Curve Pseudorandom Generator (DEC PRG) is proposed by Barker and Kelsey [2]. It is claimed (see Section 10.3.1 of [2]) that the pseudorandom generator is secure unless the adversary can solve the elliptic curve discrete logarithm problem (ECDLP) for the corresponding elliptic curve. The claim is supported only by an informal discussion. No security reduction is given, that is, it is not shown that an adversary that breaks the pseudorandom generator implies a solver for the ECDLP. Our experimental results and also empirical argument show that the DEC PRG is insecure. The attack does not imply solving the ECDLP for the corresponding elliptic curve. The attack is very efficient. It can be run on an ordinary PC. Actually, the generator is insecure because pseudorandom bits are extracted from points of the elliptic curve improperly. The authors of [2] assume that 240 least significant bits of x-coordinate of a random point of the elliptic curve over the prime field Fp, where dlog2 pe = 256, are indistinguishable from 240 uniformly distributed random bits. We show that this is not the case. Based on this observation, we construct an algorithm (an adversary) that efficiently distinguishes the pseudorandom sequences produced by the DEC PRG from the sequences of uniformly distributed random bits. We note that the complexity of our attack is proportional to 2256−240 = 216, so extracting less than 240 bits (say, 2176 bits) makes the attack impractical. However, extracting less random bits does not guarantee that there exists no other attack that successfully breaks the pseudorandom generator. The reason is that the DEC PRG is not provably secure, its security does not provably rely on the intractability of the ECDLP. To make a real provably secure pseudorandom generator one has to construct a security reduction, that is, to show that breaking the generator does imply solving a well-known and supposedly difficult problem (e.g., ECDLP, factoring, etc.) In fact, provable security might be the only argument in favor of the relatively slow DEC PRG versus more efficient generators based on hash functions and block ciphers (e.g., the generators described in Sections 10.1 and 10.2 of [2]). Unfortunately, the DEC PRG is not secure so there are no reasons to use this generator rather than the others.
Distributed acoustic receptivity in laminar flow control configurations (1992)

A model problem related to distributed receptivity to free-stream acoustic waves in laminar flow control (LFC) configurations is studied, within the Orr-Sommerfield framework, by a suitable extension of the Goldstein-Ruban theory for receptivity due to localized disturbances on the airfoil surface. The results, thus, complement the earlier work on the receptivity produced by local variations in the surface suction and/or surface admittance. In particular, we show that the cumulative effect of the distributed receptivity can be substantially larger than that of a single, isolated suction strip or slot. Furthermore, even if the receptivity is spread out over very large distances, the most effective contributions come from a relatively short region in vicinity of the lower branch of the neutral stability curve. The length scale of this region is intermediate to that of the mean of these two length scales. Finally, it is found that the receptivity is effectively dominated by a narrow band of Fourier components from the wall-suction and admittance distributions, roughly corresponding to a detuning of less than ten percent with respect to the neutral instability wavenumber at the frequency under consideration. The results suggest that the drop-off in receptivity magnitudes away from the resonant wavenumber is nearly independent of the frequency parameter.
AnInter-domain Routing Protocol forMulti-homed Wireless MeshNetworks (2007)

wouldlike tomaintain allpreviously opened connections, andtransfer themtothenewInternet gateway asquickly as This paperpresents anarchitecture andahybrid rout- possible, without anyinvolvement fromthemobile device. ingprotocol formulti-homed wireless meshnetworks that This paper presents asimple andelegant architecture that provide uninterrupted connectivity andfast handoff Our supports seamless routing inmulti-homed wireless mesh approach integrates wireless andwiredconnectivity, us- networks. Therouting protocol integrates wired andwireingmulticast groups tocoordinate decisions andseamlesslyless communication andoptimizes performance ofthehytransfer connections between several Internet gateways as brid routing, inourcasebyminimizing theusage ofwiremobile clients movebetween access points. Theprotocolless transmissions. Thehandoff between Internet gateways optimizes theuseofthewireless mediumbyshort-cutting iscompletely transparent tothemobile devices, whichhave wireless hopsthrough wired connections, paying averylow noindication ofwhen,orwhether ahandoff takes place at overhead during handoffs. Thepaperdemonstrates that all, andisfast enough forreal-time applications, suchas inter-domain handoffs occurinstantaneously, with virtuallyVoIP, whereanyinterruption inconnectivity canhavean noloss ordelay, forbothTCPandUDPconnections. adverse impact ontheservice quality. Whilesolutions exist forintra-domain handoff [5,11,15], webelieve that currently there arenoefficient andtransparent protocols for