gebhart/patrepeval huggingface dataset:
INFECTIONS OF THE THROAT DUE TO HEMOLYTIC STREPTOCOCCI AND THEIR RELATION TO ARTHRITIS AND ARTHRALGIA: I. OBSERVATIONS WITH PARTICULAR REFERENCE TO STREPTOCOCCUS EPIDEMICUS OF SEPTIC SORE THROAT (1932)

The etiologic relationship of streptococci of the throat to various forms of arthritis has been the subject of many investigations. That streptococci are the cause of arthritis has the firm support of many clinicians and research workers. The difficulties have been in the efforts of some to establish a specific streptococcus for certain types of rheumatic arthritis. The result has been a lack of uniformity in bacteriology in various forms of arthritis. The problems would not be so confusing if satisfactory differential features could be established for so-called rheumatic fever, acute rheumatic polyarthritis, infectious arthritis, rheumatoid arthritis, arthritis deformans, etc. Three types of streptococci have been described as responsible, isolated either from the blood or joints, or from the responsible infectious foci. They are the hemolytic streptococcus, Streptococcus viridans and an indifferent, nonhemolytic or nonmethemoglobin-forming streptococcus. It is not my purpose to analyze these streptococci in
Temporal chimeras produced by hypothalamic transplants (1992)

The expression of locomotor activity by golden hamsters is temporally controlled by circadian oscillators contained within the suprachiasmatic nuclei. A genetic mutation has been found that alters the freerunning period of the locomotor activity rhythm from the wild-type value of approximately 24 to approximately 20 hr in homozygous mutants. It has been shown previously that a transplant of fetal hypothalamic tissue containing the suprachiasmatic nuclei to a host rendered arrhythmic by a complete lesion of the suprachiasmatic nuclei restores rhythmicity with the freerunning period that is normally expressed by the donor genotype. We made partial lesions of the suprachiasmatic nuclei of wild-type hosts, which did not completely abolish their circadian rhythmicity, and then placed hypothalamic implants from homozygous mutant fetal donors into the lesion site. The resulting complex patterns of locomotor activity contain rhythmic components with periods of both host and donor circadian oscillators, and suggest the presence of both stimulatory and inhibitory inputs from the circadian system to the centers controlling locomotor behavior.
Empowering lifelong learners. (1999)

How can nurse managers provide staff with equitable, economical opportunities for professional development education? One hospital's point accrual system makes nurses more active in their own professional development.
Does left ventricular shape influence clinical outcome in heart failure? (2000)

In patients with dilated cardiomyopathy, the degree of spherical distortion of the LV does not correlate with prognosis.
Solubility and crystallization of fentanyl in polyisobutylene films: Parameters that control the stability of a drug in adhesive system. (2001)

The objective of this research was to investigate the crystallization of fentanyl from polyisobutylene films in order to find important parameters that determine the physical stability of a drug containing film. A model compound, fentanyl, was selected and the physicochemical properties relevant to nucleation and crystal growth were studied. The single crystal structure of fentanyl was determined and the data input in a molecular simulation program (Cerius<super> 2</super>) for visualization. Fentanyl crystals grown from heptane are monoclinic P2(1)/c, with the following cell parameters: a = 5.56A, b = 25.42A, c = 13.33A, beta = 101.2, Z = 4. The morphology of the crystals was predicted using Cerius<super>2</super> and found to be comparable to the experimental morphology of crystals grown from heptane. Solvent systems and polymeric film formulations were then screened in order to find a system that would allow us to study crystallization. The solubility of fentanyl in polyisobutylene films with and without mineral oil was determined using kinetic release studies, equilibrium studies and by monitoring crystallization from adhesive films supersaturated with fentanyl. The equilibrium method with the solubility of 0.7% w/w was the most reliable. Solubility from kinetic release studies underestimates the solubility as opposed to obtaining solubility by monitoring crystallization, which overestimated the value. The effect of supersaturation of fentanyl in these films was investigated by studying the particle size and cluster distribution in the films visually and under the microscope. It was found that drug load concentrations greater than 4% resulted in homogeneous precipitation of fine, small needles. Films of 2% and 3% drug load resulted in fewer but bigger and more defined crystals that were clustered. Crystal size decreased as the supersaturation increased leveling off for drug load concentrations higher than 4% and keeping the aspect ratio of the crystals. This is due to nucleation taking over crystal growth. Furthermore, the effect of mineral oil on the crystallization of fentanyl was investigated. There was no change in morphology or size distribution in the presence of mineral oil, however the physical properties of the film changed and thermal analysis corroborates this change in the properties of the film.
The DISCOVER codec: Architecture, Techniques and Evaluation (2007)

Distributed Video Coding is becoming more and more popular \namong the research community, because of its interesting \ntheoretical contributions and because there are still many open problems waiting to be solved. This paper introduces the codec architecture and the associated tools adopted by DISCOVER (DIStributed COding for Video sERvices), a European project* which has been devoted to the advancement of Distributed Video Coding for two years. Along with the general description and pointers to references with more detailed information, this paper also presents some of the results obtained with the \nDISCOVER codec. An extended performance analysis and the \ncodec’s executable file are both publicly available on the \nproject’s web site www.discoverdvc.org.
Hiding Lipid Presentation: Viral Interference with CD1d-Restricted Invariant Natural Killer T (iNKT) Cell Activation (2012)

The immune system plays a major role in protecting the host against viral infection. Rapid initial protection is conveyed by innate immune cells, while adaptive immunity (including T lymphocytes) requires several days to develop, yet provides high specificity and long-lasting memory. Invariant natural killer T (iNKT) cells are an unusual subset of T lymphocytes, expressing a semi-invariant T cell receptor together with markers of the innate NK cell lineage. Activated iNKT cells can exert direct cytolysis and can rapidly release a variety of immune-polarizing cytokines, thereby regulating the ensuing adaptive immune response. iNKT cells recognize lipids in the context of the antigen-presenting molecule CD1d. Intriguingly, CD1d-restricted iNKT cells appear to play a critical role in anti-viral defense: increased susceptibility to disseminated viral infections is observed both in patients with iNKT cell deficiency as well as in CD1d- and iNKT cell-deficient mice. Moreover, viruses have recently been found to use sophisticated strategies to withstand iNKT cell-mediated elimination. This review focuses on CD1d-restricted lipid presentation and the strategies viruses deploy to subvert this pathway.
Effect of High Pressure on the Reducibility and Dispersion of the Active Phase of Fischer–Tropsch Catalysts (2019)

The effect of high pressure on the reducibility and dispersion of oxides of Co and Fe supported on γ-Al<sub>2</sub>O<sub>3</sub>, SiO<sub>2</sub>, and TiO<sub>2</sub> has been studied. The catalysts, having a nominal metal content of 10 wt.%, were prepared by incipient wetness impregnation of previously calcined supports. After drying at 60 °C for 6 h and calcination at 500 °C for 4 h, the catalysts were reduced by hydrogen at two pressures, 1 and 25 bar. The metal reduction was studied by temperature-programmed reduction up to 750 °C at the two pressures, and the metal dispersion was measured by CO chemisorption at 25 °C, obtaining values between 1% and 8%. The physicochemical characterization of these materials was completed by means of chemical analysis, X-ray diffraction, N<sub>2</sub> adsorption-desorption at -196 °C and scanning electron microscopy. The high pressure lowered the reduction temperature of the metal oxides, improving their reducibility and dispersion. The metal reducibility increased from 42%, in the case of Fe/Al<sub>2</sub>O<sub>3</sub> (1 bar), to 100%, in the case of Fe/TiO<sub>2</sub> (25 bar).
A compact quad-band PIFA by using defected ground structure (2007)

The development of compact antennas plays an important role in rapidly growing mobile communication market. This paper presents a novel design technique of the quad-band small internal antenna which covers GSM-900/DCS-1800/PCS-1900/IMT-2000 bands. The handset antenna is developed within the limits of a 44times25times4 mm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sup> volume. This proposed antenna describes a new idea of increasing operational bandwidth for the compact planar inverted F antenna (PIFA). The proposed idea introduces the open-end slots in the ground plane almost all under the radiating patch. The size reduction method is attractive from the point of view of practical antenna implementation.
Posterior musculofascial reconstruction after radical prostatectomy: an updated systematic review and a meta‐analysis (2016)

To evaluate the influence of posterior musculofascial plate reconstruction (PR) on early return of continence after radical prostatectomy (RP); an updated systematic review of the literature. A systematic review of the literature was performed in June 2015, following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement and searching Medline, Embase, Scopus and Web of Science databases. We searched the terms posterior reconstruction prostatectomy, double layer anastomosis prostatectomy across the 'Title' and 'Abstract' fields of the records, with the following limits: humans, gender (male), and language (English). The authors reviewed the records to identify studies comparing cohorts of patients who underwent RP with or without restoration of the posterior aspect of the rhabdosphincter. A meta-analysis of the risk ratios estimated using data from the selected studies was performed. In all, 21 studies were identified, including three randomised controlled trials. The overall analysis of comparative studies showed that PR improved early continence recovery at 3-7, 30, and 90 days after catheter removal, while the continence rate at 180 days was statistically but not clinically affected. Statistically significantly lower anastomotic leakage rates were described after PR. There were no significant differences for positive surgical margins rates or for complications such as acute urinary retention and bladder neck stricture. The analysis confirms the benefits at 30 days after catheter removal already discussed in the review published in 2012, but also shows a significant advantage in terms of urinary continence recovery in the first 90 days. A multicentre prospective randomised controlled trial is currently being conducted in several institutions around the world to better assess the effectiveness of PR in facilitating an earlier recovery of postoperative urinary continence.
DNA and lipid bilayers: self-assembly and insertion (2008)

DNA-lipid complexes are of biomedical importance as delivery vectors for gene therapy. To gain insight into the interactions of DNA with zwitterionic and cationic (dimyristoyltrimethylammonium propane (DMTAP)) lipids, we have used coarse-grained molecular dynamics simulations to study the self-assembly of DPPC and DPPC/DMTAP lipid bilayers in the presence of a DNA dodecamer. We observed the spontaneous formation of lipid bilayers from initial systems containing randomly placed lipids, water-counterions and DNA. In both the DPPC and DPPC/DMTAP simulations, the DNA molecule is located at the water-lipid headgroup interface, lying approximately parallel to the plane of the bilayer. We have also calculated the potential of mean force for transferring a DNA dodecamer through a DPPC/DMTAP bilayer. A high energetic barrier to DNA insertion into the hydrophobic core of the bilayer is observed. The DNA adopts a transmembrane orientation only in this region. Local bilayer deformation in the vicinity of the DNA molecule is observed, largely as a result of the DNA-DMTAP headgroup attraction.
A Novel Synthesis of 2- Diethylamino-3-<i>O</i>-Nitrobenzylquinolines (2003)

Four hitherto unknown 2-diethylamino-3- o-nitrobenzylquinolines have been prepared by the reaction of a preformed 1:1 complex of β-aryl- N,N-diethylpropanamides and phosphorus oxychloride with o-acetamidobenzaldehydes.
Feed-forward Techniques for Sway Suppression in a Double-Pendulum-Type Overhead Crane (2009)

This paper presents investigations into the development of feed-forward control schemes for anti-swaying control of a double-pendulum-type overhead crane (DPTOC) system. A nonlinear DPTOC system is considered and the dynamic model of the system is derived using the Euler-Lagrange formulation. An unshaped bang-bang force input is used to determine the characteristic parameters of the system for design and evaluation of the feed-forward control techniques. Feed-forward control schemes based on input shaping and filtering techniques are to be examined. The proposed techniques are designed based on the properties of the system for anti-sway control. Simulation results of the response of the DPTOC system to the shaped inputs are presented in time and frequency domains. Performances of the control schemes are examined in terms of sway angle reduction and time response specifications. Finally, a comparative assessment of the proposed control techniques is presented and discussed.
The added value of array antennas to land-based MILSATCOMS (1988)

Land-based, transportable, military satellite communications antennas, at SHF, have reflector geometries which employ single feeds and manual steering. Using array techniques enables the expansion of antenna performance, principally in terms of beam tailoring, beam steering, spatial interference rejection, ease of use and the formation of multiple beams. The authors identify those techniques which are relevant to low- and medium-gain antennas, for transportable, quick-reaction SATCOMS.
Antiarrhythmic drugs for atrial fibrillation: Imminent impulses are emerging (2018)

Rhythm and rate strategies are considered equivalent for the management of atrial fibrillation (AF). Moreover, both strategies are intended for improving symptoms and quality of life. Despite the clinical availability of several antiarrhythmic drugs (AAD) the alternatives for the patient with comorbidities are significantly fewer because of the concern regarding many adverse effects, including proarrhythmias. The impetuous development of AF ablation gave rise to a false impression that AAD are a second line therapy. All these statements reflect, in fact, the weakness of the classical paradigm and classification regarding AAD and the gap between the current knowledge of AF mechanism and determinants and the "classical" AAD non-discriminatory action. A new paradigm in development of effective and safe AAD is based on modern knowledge of <i>vulnerable</i> parameters involved in the genesis and perpetuation of AF. New AAD will target specific triggers of AF and ion currents which are expressed preferentially in fibrillatory atrium. Such targets will include repolarizing currents and channels, as ultrarapid potassium current, two pore potassium current, the acetylcholine-gated potassium current, small-conductance calcium-dependent potassium channels, but, also, molecular targets involved in intracellular calcium kinetics, as Ca<sup>2+</sup>-calmodulin-dependent protein kinase, ryanodine receptors and non-coding miRNA. New mechanistic discoveries link AF to inflammation and modern anti-cytokine drugs. There is still a long way to win between basic research and clinical practice, but, without any doubt, antiarrhythmic drug therapy will remain and develop as a cornerstone therapy for AF not in conflict, but complementary and alternative to interventional therapy.
Influence of manufacturing variations in <i> I <sub>DDQ</sub> </i> measurements (2000)

This work presents a new -based test criterion sup- ported by the characteristics of a set of experimental testing measurements realized over different samples of industrial ICs and by the definition of the corresponding simulation model. Comparing the current consumptions of a specific circuit a significant correlation between measurements can be observed. The current behaviour can be divided into two parts: (1) a circuit dependent one, which has a major contribution, and affects equally all the devices in a given die, and (2) a smaller die dependent fraction due to variations, defective and non-defective, of each of the devices of a specific die. In this paper, a current model is defined, introducing the effects of manufacturing variations in the basic equations of the sub-threshold current to explain that double behaviour. The results show how it is possible to obtain a lot of information from measurements and how other test selection criteria can be applied to increase the testing sensitivity and quality.
Development of an Embedded Vision based Vehicle Detection System using an ARM Video Processor (2008)

Current Intelligent Transportation Systems tends to be integrated in smart environments where sensors are provided with processing and communication capabilities. This is the case of the vehicle detection system proposed in this paper. The ARM-based video processor not only deals with the video processing algorithms, but also takes advantage of the networking capabilities using an embedded operating system. Consequently, the final prototype implements the vehicle detection system as the main functionality, but offers additional features like remote detection area configuration, video delivery, remote software updating, etc. Results will show all the system capabilities as well as satisfactory vehicle detection rates.
Gelfoam embolization: a simplified technique (1979)

Gelfoam embolization: a simplified techniqueWO Bank and CW KerberAudio Available | Share
A Systematic Approach to Risk Stratification and Intervention Within a Managed Care Environment Improves Diabetes Outcomes and Patient Satisfaction (2001)

The program was successful in initiating the recommended changes in the diabetic therapeutic regimen, resulting in improved glycemic control, increased monitoring/management of diabetic complications, and greater patient and provider satisfaction. These results should have great significance in the design of future programs in MCOs aimed at improving the care of people with diabetes and other chronic diseases.
Towards the Protection and Management of Hanging Swamps on the Somersby Plateau, Central Coast, NSW (2004)

(Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
Task partitioning algorithm for intra-task dynamic voltage scaling (2008)

Dynamic voltage scaling (DVS) is a very powerful technique in reducing dynamic power consumption of CMOS circuits. Recent studies showed that intra-task DVS method which adjusts the voltage level during program execution can achieve significant energy reduction. However, the overhead of large number of voltage switching becomes a limitation for its practical implementation. In this paper, we propose a novel task partitioning algorithm for intra-task DVS which partitions a given task so that the DVS can be applied more effectively with the minimum number of voltage switching. Experimental result using H.264 decoder software shows that the proposed algorithm reduces the energy consumption by up to 25% over the conventional method.
JAK2-Centered Interactome Hotspot Identified by an Integrative Network Algorithm in Acute Stanford Type A Aortic Dissection (2014)

The precise mechanisms underlying dissections, especially those without connective tissue diseases or congenital vascular diseases, are incompletely understood. This study attempted to identify both the expression profile of the dissected ascending aorta and the interactome hotspots associated with the disease, using microarray technology and gene regulatory network analysis. There were 2,737 genes differentially expressed between patients with acute Stanford type A aortic dissection and controls. Eight interactome hotspots significantly associated with aortic dissection were identified by an integrative network algorithm. In particular, we identified a JAK2-centered expression module, which was validated in an independent gene expression microarray data set, and which was characterized by over-expressed cytokines and receptors in acute aortic dissection cases, indicating that JAK2 may play a key role in the inflammatory process, which potentially contributes to the occurrence of acute aortic dissection. Overall, the analytical strategy used in this study offered the possibility to identify functional relevant network modules and subsequently facilitated the biological interpretation in the complicated disease.
A virtual oval keyboard and a vector input method for pen-based character input (1995)

No abstract available.
Structural studies of thermal- and light- induced transitions in iron(II) spin-crossover complexes (2005)

Since the spin-crossover (SCO) effect was first discovered, considerable efforts have been made to study compounds that exhibit this phenomenon. Herein we present a selection of our most exciting results from structural studies carried out on some of the fascinating iron(II) SCO compounds we have investigated over the past few years. We discuss a range of compounds from mononuclear to bimetallic polymeric complexes. .
Novel environmental toxins: Steryl glycosides as a potential etiological factor for age‐related neurodegenerative diseases (2006)

Amyotrophic lateral sclerosis-parkinsonism dementia complex (ALS-PDC) is a unique neurodegenerative disease found on the island of Guam. This disease presents as a spectrum of neurological disorders characterized by features of ALS, parkinsonism, dementia, or a combination. The strongest epidemiological link has been to the consumption of the seeds from the cycad plant that purportedly contained a neurotoxin. Mice fed washed cycad flour show signs that mimic ALS-PDC, which include progressive deficits in motor, cognitive, and olfactory functions associated with neuron loss in the spinal cord, nigrostriatal system, cortex, hippocampus, and olfactory bulb. Through a series of chemical extractions of washed cycad flour, we identified steryl glycoside molecules as bioactive molecules that are neurotoxic in culture and in mice. A detailed review of this class of molecule revealed that the molecules are abundant in the environment, particularly in plants and bacteria. Lipid analysis showed that some bacteria that are associated with some forms of neurodegenerative disorders have the capacity to synthesize steryl glycosides. Furthermore, certain steryl glycosides have been found to be a cell stress mediator and may have some immunomodulary effects. We hypothesize that steryl glycosides are putative neurotoxins involved in the etiopathogenesis of several age-related neurodegenerative disorders.