gebhart/patrepeval huggingface dataset:
Estrogen‐induced interaction between KLF5 and estrogen receptor (ER) suppresses the function of ER in ER‐positive breast cancer cells (2009)

Kruppel-like factor 5 (KLF5) is implicated in human breast cancer by frequent genomic deletion and expressional deregulation, but the molecular mechanisms by which KLF5 affects breast tumorigenesis are still unknown. This study was conducted to examine whether and how KLF5 affects the function of estrogen receptor (ER) in breast cancer cells. Using different cell lines, we found that restored expression of KLF5 inhibited estrogen-promoted cell proliferation in ER-positive MCF-7 and T-47D cell lines but had no effect on ER-negative SK-BR-3 cells. Transcriptional activity of ER was also suppressed by KLF5, as detected by using estrogen-stimulated ER responsive element-mediated reporter assay and expression analysis of ER target genes including c-MYC and Cathepsin D (CSTD). Chromatin immunoprecipitation assays showed that KLF5 inhibited ERalpha binding to the promoter of c-myc and CSTD. Furthermore, estrogen induced an interaction between KLF5 and ERalpha. These results suggest that KLF5 inhibits the function of ERalpha in gene regulation and cell proliferation through protein interaction that interrupts the binding of ERalpha to target gene promoters to prevent target gene induction.
Effect of Long-term Oral Administration of an Immunostimulant Diet on Innate Immunity in Sea Bass (Dicentrarchus labrax) (2000)

Immunostimulants represent a modern and promising tool in aquaculture, enhancing the resistance of cultured fish to disease and stress. This study investigated the effect of a combination of dietary glucans, alpha-tocopherol and ascorbic acid on the innate immune response of cultured sea bass (Dicentrarchus labrax). After 5 weeks of adaptation on a commercial diet containing 100 p.p.m. ascorbic acid and 200 p.p.m. alpha-tocopherol, sea bass were switched to a diet supplemented with 2% beta-1.3/beta-1.6 glucans and ascorbic acid and alpha-tocopherol at 500 p.p.m. The supplemented diet was given at 2% of body weight per day over a 2-week period, every 3 months. Plasma lysozyme concentration, content and distribution of major plasma proteins and complement activity were measured prior to feeding the supplemented diet and after 40 weeks. Alternative pathways of complement activation and lysozyme activity were both significantly enhanced in fish fed on glucans and elevated doses of vitamins. No significant differences were observed in protein content or in albumin/globulin ratio. Compared to lysozyme activity, which showed marked individual variation, complement-mediated haemolytic activity has been shown to be a more reliable indicator of sea bass immunocompetence. Further studies are in progress to clarify the effect of each dietary component on the innate immune response and disease resistance.
Prime number DFT computation via parallel circular convolvers (1990)

A great deal of work has been carried out in recent years into the construction of computationally efficient small discrete Fourier transform (DFT) algorithms. Most small-DFT algorithms exploit the equivalence of prime number DFT computation with that of circular convolution, as well as Winograd's complexity theory results relating to the optimal computation of small circular convolutions, to achieve reduced-complexity solutions. The paper extends these results to the case of medium/large prime number DFT computation by means of the Agarwal—Cooley technique, whereby a multidimensional index mapping, combined with Winograd's results, converts the associated one-dimensional circular convolution into a multidimensional nested circular convolution. The resulting computational structure is then expressed in the form of an input addition phase, an output addition phase and, in between, a number of independent circular convolutions, which in hardware can be implemented in parallel, via both word-level and bit-level arithmetic techniques, to provide high-throughput solutions to the original prime number DFT computation.
Selection and Training of Teachers of the Gifted in the United States (1983)

Linda Addison examines the qualities which teachers of exceptionally able pupils should possess. She maintains that all pupils need ‘good’ teachers; teachers who are concerned with process rather than product, teachers who are creative, flexible, and have leadership qualities. However, she argues that teachers of exceptionally able pupils should be knowledgeable about the special needs and learning styles of these children and should receive appropriate specialist training. She concludes with a brief review of some teacher-training programmes in the U.S.A.
A Single-Stage AC/DC LLC Resonant Converter (2006)

A single-stage ac/dc LLC resonant converter is proposed to draw a sinusoidal line current, for achieving power factor correction (PFC). The proposed ac/dc converter composes of a boost-PFC semi-stage and a LLC-SRC semi-stage. The boost-PFC semi-stage, working in discontinuous conduction mode (DCM) functions as a power factor corrector, and the LLC-SRC semi-stage operates above the resonance to achieve zero-voltage switching (ZVS) operation. The proposed converter has the feature of variable-frequency control, which provides a constant output voltage, high power factor, high efficiency, and low component count. Finally, the experimental results are provided to verify the performance as expected.
Phase behavior of poly(ethylene oxide)-poly(propylene oxide) block copolymers in aqueous solution (1993)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPhase behavior of poly(ethylene oxide)-poly(propylene oxide) block copolymers in aqueous solutionPer LinseCite this: J. Phys. Chem. 1993, 97, 51, 13896–13902Publication Date (Print):December 1, 1993Publication History Published online1 May 2002Published inissue 1 December 1993https://pubs.acs.org/doi/10.1021/j100153a072https://doi.org/10.1021/j100153a072research-articleACS PublicationsRequest reuse permissionsArticle Views603Altmetric-Citations137LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Lexical and Syntactic Features of ESL Writing by Students at Different Levels of L2 Proficiency (1994)

learner. Toronto, Canada: Ontario Institute of Studies for Education. O'Malley, J. M., Chamot, A. U., Stewner-Manzanares, G., Russo, R. P., & Kupper, L. (1985). Learning strategy applications with students of English as a second language. TESOL Quarterly, 19, 557-584. O'Malley, J. M., & Chamot, A. U. (1990). Learning strategies in second language acquisition. Cambridge: Cambridge University Press. Oxford, R. L. (1989). Use of language learning strategies: A synthesis of studies with implications for strategy training. System, 17, 235-247. Oxford, R. L. (1990). Language learning strategies: What every teacher should know. New York: Newbury House. Reid, J. M. (1987). The learning style preferences of ESL students. TESOL Quarterly, 21, 87-112. Rubin, J. (1975). What the good language learner can teach us. TESOL Quarterly, 9, 41-51. Rubin, J., & Thompson, I. (1982). How to be a successful language learner. Boston: Heinle & Heinle.
The feasibility of developing a borehole sparker for geothermal wells (1977)

A feasibility study was undertaken to determine the practicality of designing a borehole sparker (underwater electric discharge) seismic source for use in an extremely harsh environment (69MPa @ 275{degrees}C = 10,000 psi @ 527{degrees}F). Important electrical and hydrodynamic parameters of underwater spark discharges, component availability, and past accomplishments of others in the field of borehole-to-borehole sparker surveying are discussed. It is concluded that this instrument could be economically developed.
Surface replacement of the shoulder (2011)

♦ The design of the surface replacement arthroplasty has evolved over the past 20 years. From cemented prostheses such as the SCAN, to cementless prostheses such as the Copeland, the basic concept and design of the surface replacement favouring maximal bone preservation has remained constant. ♦ Indications and surgical technique have been refined over this period, the latest modification being the use of computer-assisted navigation to optimise the size and position the implant in situ. ♦ Surface replacement prosthesis has demonstrated clinical results at least equal to those of conventional stemmed prostheses.
Secure Adiabatic Logic: a Low-Energy DPA-Resistant Logic Style. (2008)

Abstract. The charge recovery logic families have been designed several years ago not in order to eliminate the side-channel leakage but to reduce the power consumption. However, in this article we present a new charge recovery logic style not only to gain high energy efficiency but also to achieve the resistance against side-channel attacks (SDA) especially against differential power analysis (DPA) attacks. Simulation results show a significant improvement in DPA-resistance level as well as in power consumption reduction in comparison with DPA-resistant logic styles proposed so far. 1
The effect of holes on the injection-induced breakdown in n-channel MOSFET's (1985)

The holes generated by impact ionization are spread over the vicinity of the source. At high drain biases, the hole density near the source is found to be larger than the impurity doping level by simulation. The highly concentrated holes decrease source potential barrier at high drain voltages and the source current is significantly increased.
Properties of autonomous 3′→5′ exonucleases (2009)

Autonomous 3'-->5' exonucleases (AE) are not bound covalently to DNA polymerases, but they are often included into the replicative complexes. Intracellular AE overproduction in bacteria results in sharp suppression of mutagenesis, whereas inactivation of these enzymes in bacteria and fungi leads to an increase in mutagenesis frequency by 2-3 orders of magnitude. Correction of DNA polymerase errors in vitro occurs after addition of AE to the incubation medium. This correction is clearly manifested under conditions of mutational stress (during induced but not spontaneous mutagenesis), for instance, with an imbalance of dNTPs--error-prone conditions. At equimolar dNTP (error-free conditions), the correction is relatively weak. The gene knockout of both alleles of the major AE gene in mice does not influence spontaneous mutagenesis though a substantial increase could be expected. The frequency of induced mutagenesis has not been yet measured, though the inactivation of AE could increase the frequency of mutagenesis. Complete inactivation of the major AE leads to inflammatory myocarditis and a 5-fold reduction of life span of mice. Dominant heterozygous mutations were found in various loci of the AE gene, which caused the development of Aicardi-Goutieres (autosomal recessive encephalopathy) syndrome, familial chilblain lupus, systemic lupus erythematosus, retinal vasculopathy, and cerebral leukodystrophy. In the nucleus, AE have a corrective function, but after transition into cytoplasm these enzymes destroy aberrant DNA that appears during replication and thereby save the cells from autoimmune diseases. Depending on their intracellular localization, AE carry out various biological functions but employ the same mechanism of the catalyzed reactions.
Beta-xylosidase activity of a GH3 glucosidase/xylosidase from yak rumen metagenome promotes the enzymatic degradation of hemicellulosic xylans (2011)

This was the first to report the β-xylosidase activity of family 3 β-glucosidase/xylosidase functioned in the degradation of hemicellulosic xylans. The bifunctional β-glucosidase/xylosidase property of RuBGX1 can be used in simultaneous saccharification of cellulose and xylan into fermentable glucose and xylose.
Time Course and Magnitude of Illusory Translation Perception During Off-Vertical Axis Rotation (2005)

Human spatial orientation relies on vision, somatosensory cues, and signals from the semicircular canals and the otoliths. The canals measure rotation, whereas the otoliths are linear accelerometers, sensitive to tilt and translation. To disambiguate the otolith signal, two main hypotheses have been proposed: frequency segregation and canal-otolith interaction. So far these models were based mainly on oculomotor behavior. In this study we investigated their applicability to human self-motion perception. Six subjects were rotated in yaw about an off-vertical axis (OVAR) at various speeds and tilt angles, in darkness. During the rotation, subjects indicated at regular intervals whether a briefly presented dot moved faster or slower than their perceived self-motion. Based on such responses, we determined the time course of the self-motion percept and characterized its steady state by a psychometric function. The psychophysical results were consistent with anecdotal reports. All subjects initially sensed rotation, but then gradually developed a percept of being translated along a cone. The rotation percept could be described by a decaying exponential with a time constant of about 20 s. Translation percept magnitude typically followed a delayed increasing exponential with delays up to 50 s and a time constant of about 15 s. The asymptotic magnitude of perceived translation increased with rotation speed and tilt angle, but never exceeded 14 cm/s. These results were most consistent with predictions of the canal-otolith-interaction model, but required parameter values that differed from the original proposal. We conclude that canal-otolith interaction is an important governing principle for self-motion perception that can be deployed flexibly, dependent on stimulus conditions.
Numerical simulation of an elve modulated by a gravity wave (2015)

Abstract Recent video observations have shown that elves—the visible manifestation of the lightning electromagnetic pulse (EMP) interacting with the lower ionosphere—can be modulated by neutral density fluctuations at lower ionosphere altitudes due to gravity waves. The elve emissions thus illuminate the gravity wave structure. Here we use a finite difference time domain (FDTD) model of the lightning EMP to simulate elve emissions in the presence of neutral density fluctuations representative of gravity waves. We show that observable elve striations can be generated by gravity waves with a neutral density perturbation of as low as 5% at elve altitudes near 85 km. Higher perturbations lead to more pronounced striations. The depth of the optical signature perturbation is found to be similar in magnitude to the neutral density perturbation at elve altitudes, although the relationship depends on viewing geometry, gravity wave geometry, and the elve‐causative lightning peak current moment.
Longitudinal melanonychia (LM) in childhood: Clinical and histological study (1995)

info:eu-repo/semantics/published
Optimal Path Planning and Control of Quadrotor Unmanned Aerial Vehicle for Area Coverage (2014)

An Unmanned Aerial Vehicle (UAV) is an aircraft without a human pilot on board.Its flight is controlled either autonomously by computers onboard the vehicle, or remotely by a pilot on the ground, or by another vehicle.In recent years, UAVs have
Diseases of Salt Water Fish (1977)

In a previous article (ISU Veterinarian Vol. 38, No. 2, 1976), the environmental problems associated with keeping saltwater fish were reported. This article will deal with the diagnosis and treatment of common coral fish diseases.
Energy Recovery from Wastewater Treatment Plants in the United States: A Case Study of the Energy-Water Nexus (2010)

This manuscript uses data from the U.S. Environmental Protection Agency to analyze the potential for energy recovery from wastewater treatment plants via anaerobic digestion with biogas utilization and biosolids incineration with electricity generation. These energy recovery strategies could help offset the electricity consumption of the wastewater sector and represent possible areas for sustainable energy policy implementation. We estimate that anaerobic digestion could save 628 to 4,940 million kWh annually in the United States. In Texas, anaerobic digestion could save 40.2 to 460 million kWh annually and biosolids incineration could save 51.9 to 1,030 million kWh annually.
A new algorithm for multiplication in finite fields (1989)

A new algorithm is presented for computing the product of two elements in a finite field by means of sums and products in a fixed subfield. The algorithm is based on a normal basis representation of fields and assumes that the dimension m of the finite field over the subfield is a highly composite number. A very fast parallel implementation and a considerable reduction in the number of computations are allowed, in comparison to some methods discussed in the literature.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Nuclear Weapons: Cleanup Without End (2000)

RETURN TO ISSUEPREVNewsNEXTNuclear Weapons: Cleanup Without EndJEFF JOHNSONCite this: Chem. Eng. News 2000, 78, 33, 10–11Publication Date (Print):August 14, 2000Publication History Published online12 November 2010Published inissue 14 August 2000https://pubs.acs.org/doi/10.1021/cen-v078n033.p010ahttps://doi.org/10.1021/cen-v078n033.p010anewsACS PublicationsCopyright © 2000 American Chemical SocietyArticle Views9Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options SUBJECTS:Groundwaters,Land use,Nuclear weapons,Wastes Get e-Alerts
Integrated microfluidic biochips for immunoassay and DNA bioassays (2005)

Bioassays involve multi-stage sample processing and fluidic handling, which are generally labor-intensive and time-consuming. Using microfluidic technology to integrate and automate all these steps in a single chip device is highly desirable in many practical applications such as clinical diagnostic and in-field environmental testing. We have developed self-contained and fully integrated biochip systems for immunoassay and DNA analysis. These microfluidic biochip devices can perform detection of multiple bioagents (including antigens and DNA) using electrochemical detection methods. Microfluidic mixer, valves, pumps, channels, chambers, and Combimatrix microelectrode array are integrated to perform parallel immunoassays to detect infectious particles (viruses and bacteria) from complex biological samples in a single, fully automated biochip device. All microfluidic components use very simple and inexpensive approaches in order to reduce chip complexity. Back-end detection is accomplished using an enzyme-based electrochemical detection method that has many advantages including high sensitivity ( approximately fM) and simple apparatus. The sensor is a miniaturized array of individually addressable microelectrodes controlled by active CMOS circuitry. Pathogenic bacteria and DNA detections are both demonstrated. The devices with capabilities of on-chip sample processing and detection provide a cost-effective solution to direct sample-to-answer biological analysis for point-of-care genetic analysis, disease diagnosis, and in-field bio-threat detection.
Control E-commerce security (2010)

Electronic commerce has been very popular in the recent years. However, security is one of the barriers, which affects the development of E-commerce. How should merchants of E-commerce solve this problem and maintain a secure environment for their customers? How do customers protect their confidential data when they are shopping on-line? This thesis discusses various common attacks, and presents the protection solutions according to those attacks. Because attacks may take place on the customers and the sellers site, the method of defense has been discussed from these two sides. Furthermore, this thesis has provided the basic plan for developing an E-commerce site, which includes E-commerce security policies design and disaster recovery plan. The goal of this thesis is to provide the basic security knowledge of E-commerce for merchants and customers, and help them to confidently run a safe E-business and conduct shopping online safely.
L'Eurorégion et le réseau C-6 : l'émergence du suprarégionalisme en Europe du Sud ? (1995)

Morata Francesc. L'Eurorégion et le réseau C-6 : l'émergence du suprarégionalisme en Europe du Sud ?. In: Pôle Sud, n°3, 1995. L'Europe au sud, sous la direction de Emmanuel Négrier . pp. 117-127.
Highly Efficient Oxidative Desulfurization of Fuels by Lewis Acidic Ionic Liquids Based on Iron Chloride (2013)

Abstract Acidic ionic liquids (ILs) have been employed as extractant and catalyst in the oxidative desulfurization (ODS) process of fuels in recent years. Several Lewis acidic ionic liquids [C 6 3 MPy]Cl/ n FeCl 3 (molar fraction n = 0.5, 1, 2, 3) and [C 6 MIM]Cl/FeCl 3 were prepared and used to remove the aromatic sulfur compounds dibenzothiophene and benzothiophene from fuels. In the ODS process, the used ILs acted as both extractant and catalyst with 30 wt % hydrogen peroxide aqueous solution as oxidant. The effects of Lewis acidity of ILs, IL's cation structure, molar ratio of O/S, reaction temperature, and different sulfur compounds on the sulfur removal of model oil were investigated. The results indicated that the sulfur removal for dibenzothiophene was affected by Lewis acidity of ILs and nearly reached 100 % by [C 6 3 MPy]Cl/FeCl 3 at conditions of 298 K, IL/oil mass ratio of 1/3, O/S molar ratio of 4/1, in 20 min. The sulfur removal of real gasoline reached 99.7 % after seven ODS runs in the [C 6 3 MPy]Cl/FeCl 3 ‐H 2 O 2 system.
Inductorless Bandpass Characteristics Using All-Pass Networks (1968)

Bandpass filters without inductors can be realized by using all-pass frequency-sensitive phase-shift networks. Filters with <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">Q</tex> values approaching 1000 have been constructed. A method of reducing the <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">Q</tex> sensitivity is reported.