gebhart/patrepeval huggingface dataset:
Force-based load balancing in co-located UMTS/GSM networks (2005)

Currently UMTS networks are rolled out to compliment existing GSM networks. As most UMTS mobiles will also support GSM, the question of which system to select for a given service emerges. In order to exploit the differences between radio access technologies, common radio resource management (CRRM) is employed, i.e. common management of the whole radio resources such that the assignment of mobiles to different radio technologies is flexible and considers the specific advantages of each system. The focus of the paper is on intelligent algorithms to decide the balancing of the load between the different radio technologies. We study algorithms for optimum assignment of mobiles to a radio technology during call setup as well as during the call. The decision is based on an intelligent evaluation of various aspects of the radio link. Our algorithm is based on an approach previously employed to balance the load of distributed computing systems.
IDAC: An Interactive Design Tool for Analog CMOS Circuits (2009)

A design system has been developed which is able to design transconductance amplifiers, operational amplifiers, low-noise BIMOS amplifiers, voltage and current references, quartz oscillators, comparators, and oversampled A/D converters including their digital decimation filter starting from building-block and technology specifications.
Heart Rate Control With I<sub>f</sub> Inhibitor, Ivabradine, in Japanese Patients With Chronic Heart Failure　– A Randomized, Double-Blind, Placebo-Controlled Phase II Study – (2016)

Ivabradine starting at 2.5 or 5 mg BID effectively reduced resting HR in Japanese HF patients. Ivabradine at the starting dose of 2.5 mg BID could be safer than 5 mg BID. (Circ J 2016; 80: 668-676).
Combined DV-X.alpha. and gas-phase UV photoelectron spectroscopic investigation of the electronic structures of tetravalent titanium, zirconium, molybdenum, and thorium 1-sila-3-metallacyclobutane metallocene complexes (1992)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCombined DV-X.alpha. and gas-phase UV photoelectron spectroscopic investigation of the electronic structures of tetravalent titanium, zirconium, molybdenum, and thorium 1-sila-3-metallacyclobutane metallocene complexesEnrico Ciliberto, Santo Di Bella, Antonio Gulino, Ignazio Fragala, Jeffrey L. Petersen, and Tobin J. MarksCite this: Organometallics 1992, 11, 4, 1727–1737Publication Date (Print):April 1, 1992Publication History Published online1 May 2002Published inissue 1 April 1992https://doi.org/10.1021/om00040a050Request reuse permissionsArticle Views95Altmetric-Citations16LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (1006 KB) Get e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
Efeito do substrato sobre a incidência e biocontrole do tombamento de chicória causado por Rhizoctonia solani (2013)

Para a producao de mudas de olericolas sao utilizados diversos tipos de substratos que variam em suas caracteristicas quimicas, fisicas e nutricionais. Essas diferencas podem influenciar na incidencia do tombamento causado por Rhizoctonia solani e na atividade de biocontrole de pseudomonas. No presente estudo, objetivou-se avaliar a capacidade de duas rizobacterias de reduzir a incidencia do tombamento de mudas de chicoria causado por R. solani em dois substratos comerciais, Multiplant e Baseplant, e um substrato orgânico a base de vermicomposto. Os substratos foram infectados com R. solani e apos 48 h foram regados com suspensoes bacterianas das estirpes 29 e 102 em meio King B. Ambas as estirpes reduziram significativamente a media do numero de plântulas tombadas apos a emergencia das plântulas de chicoria em vermicomposto e aumentaram significativamente a media do numero de plântulas sadias nesse substrato. Em contraste, nao houve efeito da inoculacao das duas estirpes nos substratos Multiplant e Baseplant sobre a severidade do tombamento. As estirpes 102 e 29 apresentam potencial antagonistico a R.  solani , porem a atividade de biocontrole e dependente do substrato utilizado para a formacao das mudas de chicoria.
Bisphenol A Exposure Is Associated with <i>in Vivo</i> Estrogenic Gene Expression in Adults (2011)

Because activation of nuclear-receptor-mediated pathways by BPA is consistently found in laboratory studies, such activation in humans provides evidence that BPA is likely to function as a xenoestrogen in this sample of adults.
Multi junction spectral response measurement setup based on high power leds for subcell selection (2007)

Contains fulltext : 36253.pdf (author's version ) (Closed access)
One Change at a Time: Pop up Usability Testing (2016)

Library staff know the bizarre tricks and jargon we use to navigate our system and websites while our users continue to struggle and never get as adjusted. The University of Minnesota Libraries have committed to running monthly web usability tests in-house that illustrate the user's perspective. These tests guide us in implementing changes to our system and websites. With little more than a spare computer, Skype, and a group of diligent and willing staff, we've been able to learn incredibly useful things about our web sites and applications. In this session, we'll describe our process, some examples of evaluations we've run, what we've done with the information, lessons we've learned along the way, and we'll show you how you too can run usability tests at your library.
Power-based signal-to-diffuse ratio estimation using noisy directional microphones (2014)

The signal-to-diffuse ratio (SDR), which describes the power ratio between the direct and diffuse component of a sound field, is an important parameter in many applications. This paper proposes a power-based SDR estimator which considers the auto power spectral densities obtained by noisy directional microphones. Compared to recently proposed estimators that exploit the spatial coherence between two microphones, the power-based estimator is more robust at lower frequencies given that the microphone directivities are known with sufficiently high accuracy. The proposed estimator can incorporate more than two microphones and can therefore provide accurate SDR estimates independently of the direction-of-arrival of the direct sound. We further propose a method to determine the optimal microphone orientations for a given set of directional microphones. Simulations show the practical applicability.
Teleradiotherapy Network: Applications and Feasibility for Providing Cost-Effective Comprehensive Radiotherapy Care in Low- and Middle-Income Group Countries for Cancer Patients (2015)

Globally, new cancer cases will rise by 57% within the next two decades, with the majority in the low- and middle-income countries (LMICs). Consequently, a steep increase of about 40% in cancer deaths is expected there, mainly because of lack of treatment facilities, especially radiotherapy. Radiotherapy is required for more than 50% of patients, but the capital cost for equipment often deters establishment of such facilities in LMICs. Presently, of the 139 LMICs, 55 do not even have a radiotherapy facility, whereas the remaining 84 have a deficit of 61.4% of their required radiotherapy units. Networking between centers could enhance the effectiveness and reach of existing radiotherapy in LMICs. A teleradiotherapy network could enable centers to share and optimally utilize their resources, both infrastructure and staffing. This could be in the form of a three-tier radiotherapy service consisting of primary, secondary, and tertiary radiotherapy centers interlinked through a network. The concept has been adopted in some LMICs and could also be used as a “service provider model,” thereby reducing the investments to set up such a network. Teleradiotherapy networks could be a part of the multipronged approach to address the enormous gap in radiotherapy services in a cost-effective manner and to support better accessibility to radiotherapy facilities, especially for LMICs.
Erythropoietin facilitates definitive endodermal differentiation of mouse embryonic stem cells via activation of ERK signaling (2017)

Artificially generated pancreatic β-cells from pluripotent stem cells are expected for cell replacement therapy for type 1 diabetes. Several strategies are adopted to direct pluripotent stem cells toward pancreatic differentiation. However, a standard differentiation method for clinical application has not been established. It is important to develop more effective and safer methods for generating pancreatic β-cells without toxic or mutagenic chemicals. In the present study, we screened several endogenous factors involved in organ development to identify the factor, which induced the efficiency of pancreatic differentiation and found that treatment with erythropoietin (EPO) facilitated the differentiation of mouse embryonic stem cells (ESCs) into definitive endoderm. At an early stage of differentiation, EPO treatment significantly increased <i>Sox17</i> gene expression, as a marker of the definitive endoderm. Contrary to the canonical function of EPO, it did not affect the levels of phosphorylated JAK2 and STAT5, but stimulated the phosphorylation of ERK1/2 and Akt. The MEK inhibitor U0126 significantly inhibited EPO-induced <i>Sox17</i> expression. The differentiation of ESCs into definitive endoderm is an important step for the differentiation into pancreatic and other endodermal lineages. This study suggests a possible role of EPO in embryonic endodermal development and a new agent for directing the differentiation into endodermal lineages like pancreatic β-cells.
Global Warming and Trans-Boundary Movement of Waterborne Microbial Pathogens (2010)

Potential ramifications of climate change, as they relate to waterborne pathogens (primarily viruses, bacterial and parasitic protozoa), are the focus of this chapter. It seems clear that climate change will impact on waterborne pathogens in various ways (Rose et al. 2001), pertinent to transboundary issues are: (1) increases in intense storm events (increasing sewage/animal waste flows into waterways/aquifers) (Charron et al. 2004; Schijven and de Roda Husman 2005; Yang and Goodrich 2009; De Toffol et al. 2009; Richardson et al. 2009); (2) warmer surface water temperatures or salinity changes (for increased autochthonous pathogen growth) (Niemi et al. 2004; Koelle et al. 2005; Lebarbenchon et al. 2008); and (3) changes in food production, as most obvious in animal diseases (Lightner et al. 1997; Rapoport and Shimshony 1997), but also of concern with zoonoses and from changes in social behavior (Schwab et al. 1998; Nancarrow et al. 2008; CDC 2009a). When considering trans-boundary effects on waterborne pathogens, it is therefore the flow of pathogens in surface water (fresh and marine) and in groundwater, as well as in the varying ways water is used/reused in association with human activities (e.g., food production) that are the trans-boundary issues discussed in this chapter (examples in Table 5.1). Changes in infectious and vector-borne diseases associated with rising sea levels, losses of habitat, international travel etc. are not addressed in this chapter.
Structuralinsightintotheinhibitionoftubulinbyvinca domain peptide ligands (2008)

The tubulin vinca domain is the target of widely different microtubule inhibitors that interfere with the binding of vinblastine. Although all these ligands inhibit the hydrolysis of GTP, they affect nucleotide exchange to variable extents. The structures of two vinca domain antimitotic peptides—phomopsin A and soblidotin (a dolastatin 10 analogue)—bound to tubulin in a complex with a stathmin-like domain show that their sites partly overlap with that of vinblastine and extend the definition of the vinca domain. The structural data, together with the biochemical results from the ligands we studied, highlight two main contributors in nucleotide exchange: the flexibility of the tubulin subunits’ arrangement at their interfaces and the residues in the carboxy-terminal part of the b-tubulin H6–H7 loop. The structures also highlight common features of the mechanisms by which vinca domain ligands favour curved tubulin assemblies and
Enhanced DNA Separation Rates in Nano-Platinum Doped Agarose (2008)

In this work, nanoparticle-doped matrices for DNA separation at low voltages are described.High conductivity agarose gels doped with platinum nano-particles have been synthesized and characterized by TEM, EDS and SEM.This new doping technique for agarose gels enhances the dielectric constant of the gels by up to 1.5 folds as compared to undoped gel, decreases the resistance (from 97 ohms to about 60 ohms) and increases DNA mobility by 1.5 times (from 6 6 × 10 -5 cm 2 /V • sec to 9 3 × 10 -5 cm 2 /V • sec) at lower operating electric fields (8 V/cm).We believe that the faster movement of DNA arises from an increased dielectric constant and a reduced resistance of the doped material resulting in increased ionic mobility.Using image analysis tools, we have also observed that there is no band broadening effects in the platinum doped gel sample, which indicate no appreciable temperature rise due to incorporation of platinum nanoparticles in agarose gel.
Characteristics of tourist patients in an emergency department in a Mediterranean destination (2008)

EDs can be expected to manage tourist patients presenting for traumatic injuries and circulatory disorders. Clinical differences relating to patients' nationality might help in the development of targeted patient education and injury-prevention programs. Emergency physicians and the tourism industry should recognize the challenges of caring for this growing and aged patient population.
Preface (1993)

This volume is comprised of papers that were presented at the Fifth Topical Meeting on Ultrafast Electronics and Optoelectronics (formerly Picosecond Electronics and Optoelectronics), held in San Francisco, January 23-25, 1993. The purpose of this topical meeting, since its inception in 1985, has been to foster greater interaction between researchers in the electronics and optoelectronics communities who share a common interest in the physics and technology of ultrafast electronics and optoelectronics devices, their multigigahertz applications, and ultrafast measurement techniques. The number of abstracts submitted to this meeting was considerably larger than for the previous meetings, indicating the appeal of this interdisciplinary approach and the growing importance of this field. This preface serves as a summary and a guide to these Proceedings.
ChemInform Abstract: A STEREOCHEMICAL STUDY OF THE REACTIONS OF TRISUBSTITUTED PHOSPHITES WITH N‐CHLORODIALKYLAMINES (1977)

Abstract Verschiedene cyclische Phosphite (I) und (II) werden mit N‐Chloraminen (III) umgesetzt und die erhaltenen Mischungen isomerer Amide (IV) und (V) in Relation zu den Reaktionsbedingungen untersucht.
Cellulose propionylpropionate as a side product in the reaction of cotton cellulose with propionyl chloride (1967)

Abstract In the reaction of cotton cellulose fiber with propionyl chloride in pyridine–DMF medium, the degree of substitution based on weight gain was much higher than that based on saponification. Gas–liquid chromatograms of the pyrolysis products of the samples showed an extra peak. This was identified as 3‐pentanone, which arises from the pyrolysis of α‐propionylpropionic acid, a substance which was proposed by Malm and co‐workers as a possible side product. This conclusion was further confirmed by the infrared and NMR spectra of the liquid, collected fractionally on pyrolysis of the sample. Quantitative GLC showed that one òut of every four hydroxyl groups is substituted with an α‐propionylpropionyl moiety, the rest with propionyl groups. A possible mechanism for the side reaction has been proposed.
Effects of Phenobarbital on Cerebral Blood Flow Velocity After Endotracheal Suctioning in Premature Neonates (2001)

In very low-birth-weight neonates, endotracheal suctioning is associated with decreases in TcPO(2) and increases in MABP and AUVC. Treatment with phenobarbital attenuates the increases in MABP and AUVC but not the decreases in TcPO(2) after endotracheal suctioning.
Biallelic <i>COLGALT1</i> variants are associated with cerebral small vessel disease (2018)

Biallelic COLGALT1 variants cause cerebral small vessel abnormalities through a common molecular pathogenesis with COL4A1/COL4A2-related disorders. Ann Neurol 2018;84:843-853.
The Relationship of Mucus Concentration (Hydration) to Mucus Osmotic Pressure and Transport in Chronic Bronchitis (2020)

Rationale: Chronic bronchitis (CB) is characterized by persistent cough and sputum production. Studies were performed to test whether mucus hyperconcentration and increased partial osmotic pressure, in part caused by abnormal purine nucleotide regulation of ion transport, contribute to the pathogenesis of CB.
Vascular reactivity after balloon angioplasty in an atherosclerotic rabbit. (1990)

Alterations in vessel wall reactivity (VR) at or adjacent to the dilation site after balloon angioplasty (BA) may vary according to the inflation protocol and the time after angioplasty and may influence outcome. In 64 atherosclerotic rabbit femoral arteries, we evaluated VR after BA with intravenous ergonovine (ERGO) (40 micrograms/min for 5 minutes) and intra-arterial nitroglycerin (NTG) (2,500 micrograms single bolus) 24-72 hours and 28 days after BA. Comparisons were made with atherosclerotic, nonangioplastied, age-matched controls. BA was standardized to three 1-minute inflations, each 1 minute apart. For each balloon size, 2.5- (appropriate size) or 3.0-mm (oversized) vessels were allocated to either 5 or 10 atm inflation pressure. For the analysis, four groups were compared: Group 1, 3.0/5; group 2, 3.0/10; group 3, 2.5/5, and group 4, 2.5 mm/10 atm. Angiographic diameters were measured at, proximal, and distal to the lesion at baseline, 10 minutes after ERGO, and 5 minutes after NTG. Angiograms were measured with electronic calipers by two blinded observers. All segments of control vessels vasoconstricted to ERGO and vasodilated to NTG (p less than 0.05 versus baseline), indicating a normal response. At 24-72 hours after dilatation, the angioplasty sites for all inflation pressure/balloon size combinations were not responsive to either ERGO or NTG. All segments distal to the dilatation sites vasoconstricted to ERGO and dilated to NTG (p less than 0.05 versus baseline), indicating a normal response. Proximal segments of vessels dilated with a 2.5-mm balloon (appropriate size) responded positively to both stimuli (p less than 0.05). Those vessels dilated with a large balloon (3.0 mm) were nonreactive in the segment proximal to the angioplasty site. Twenty-eight days later angioplasty sites dilated with a 2.5-mm balloon (appropriately sized) regained reactivity; however, segments dilated with a large balloon (3.0 mm) remained unresponsive. All proximal segments, including those from vessels dilated with a large balloon, reacted positively. All distal segments reacted appropriately. Restenosis rates were not different between the over- and appropriately sized balloon groups. These data demonstrate that immediately after angioplasty, vessels lose reactivity at the dilatation site. Those vessels dilated with the smaller-size balloon (2.5 mm) regained reactivity. For large balloons, reactivity is not regained at 28 days. For segments proximal to the site of dilatation, transient loss of reactivity is seen only when a large balloon is used. Thus, acute closure originating at the site of dilatation is not a result of spasm.(ABSTRACT TRUNCATED AT 400 WORDS)
Towards early in vivo photoacoustic malaria diagnosis with 10,000-fold sensitivity improvement (Conference Presentation) (2017)

Roughly 0.6 million people die each year from malaria due to lack of early diagnosis and well-timed treatment. Our previous study demonstrated great potential of in vivo photoacoustic (PA) flow cytometry (PAFC) for early diagnosis of deadly diseases with focus on cancer and thromboembolic complications. Here we demonstrate potential of advanced PAFC platforms using new laser, ultrasound transducer array and recording system to detect infected red blood cells (iRBCs) with malaria-associated pigment hemozoin which has a higher PA contrast than blood background. Mature parasites of human infecting species such as P. falciparum characteristically sequester mature iRBCs in the capillary bed and display synchrony in their reproductive cycle. To address this issue prior to clinical application, new PAFC platform was verified in a pre-clinical study using new animal models. Specifically, we used P. chabaudi (a rodent malaria species that mimics the characteristics of the most virulent human counterpart) to estimate the detection sensitivity with immature ring-stage parasites in peripheral blood, compared PA signals from the differing species, and examined the relationship between PA signal amplitudes and level of blood oxygenation. Based on previous successful trials on melanoma patients with melanin as an intrinsic PA marker, which has similar absorption as hemozoin, we believe that after additional malaria–related clinical trials, PAFC with a small 1064 nm laser and wearable a cost-effective, easy-to-use, watch-like, safe PA probe will provide malaria diagnosis in humans at parasitemia levels 10e4 -times lower than the current gold standard of diagnosis, the Giemsa-stained blood smear. It can reduce malaria-related mortality by well-timed treatment, especially in children in malaria-endemic countries.
SOMBRERO-a solid breeder moving bed KrF laser driven IFE power reactor (2002)

SOMBRERO, a conceptual design study of a 1000-MWe KrF laser driven IFE (inertial fusion energy) power reactor utilizing direct drive targets with near symmetric illumination, is described. The chamber is constructed of a low-activation carbon/carbon composite and the blanket consists of a moving bed of solid Li/sub 2/O particles flowing through the chamber by gravity. The particles are transported through the intermediate heat exchanger and around the loop in a fluidized state by He gas at 0.2 MPa. There are 60 laser beams in near-symmetric distribution; the laser energy is 3.4 MJ; the target gain is 118; and the rep-rate is 6.7 Hz. The chamber has a cylindrical central region with conical ends, a minimum radius of 6.5 m, and a blanket/reflector thickness of 1 m at the midplane giving a tritium breeding ratio of 1.25 and an overall energy multiplication of 1.08. A grazing incidence metallic mirror is located 30 m from the target, and the final focusing dielectric coated mirror which is shielded from direct neutrons is located at 50 m. The inlet temperature of the Li/sub 2/O particles is 550 degrees C, the equilibrated outlet temperature is 740 degrees C; and the power cycle efficiency is 47%. Using a laser efficiency of 7%, the driver power is 325 MWe. The gross power output is 1360 MWe, giving a net power output of 1000 MWe, with 360 MWe used for the driver and auxiliary equipment.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>