gebhart/patrepeval huggingface dataset:
335 Comparison of crack propagation behavior between rubber modified and unmodified epoxy adhesives using four point bend, end notched flexure specimens (2006)

Mode II fracture behavior of rubber modified and unmodified epoxy adhesives are studied. Especially to investigate the crack growth behavior in adhesive layers, adhesively bonded end-notched flexure (ENF) specimens were loaded in four point bending. Experimental results were arranged as R-curves. Then, a finite element analysis was also conducted to investigate stress distributions near the crack tip. Based on these results, the effect of rubber modification on the crack initiation and propagation behavior was discussed.
Stable fluorinated cyclobutenyl cations (1976)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTStable fluorinated cyclobutenyl cationsB. E. Smart and G. S. ReddyCite this: J. Am. Chem. Soc. 1976, 98, 18, 5593–5597Publication Date (Print):September 1, 1976Publication History Published online1 May 2002Published inissue 1 September 1976https://pubs.acs.org/doi/10.1021/ja00434a031https://doi.org/10.1021/ja00434a031research-articleACS PublicationsRequest reuse permissionsArticle Views72Altmetric-Citations21LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
All-optical 3R regeneration using SOA-based polarization discriminating switch (2006)

Optical 3R regeneration is of great interest due to its ability to enhance the system margins in photonic network, because it enables to reset transmission impairments induced by channel interaction distortion, accumulation of amplified spontaneous emission (ASE) noise, chromatic dispersion and non-linearities of optical fibers and so forth. In comparison to electrical 3R regenerators, optical 3R regenerators are expected to be less complex and require less high-speed electronic components owing to simple optical signal processing, leading to small footprint, low power consumption and low cost. In this paper, we describe an optical 3R regenerator operable with carrier-suppressed return-to-zero (CS-RZ) modulation format which will be employed in dense WDM (DWDM) network to increase the efficiency of bandwidth utilization. We have demonstrated 3R regenerative transmission using 100 GHz-spacing 40 Gbit/s 5 WDM CS-RZ signals so as to confirm that a DWDM filtering effect can be drastically mitigated by the 3R regenerator.
Continuous Flow Microwave-Assisted Reaction Optimization and Scale-Up Using Fluorous Spacer Technology (2008)

Microwave-assisted organic synthesis in a laboratory-scale monomodal microwave reactor is investigated for continuous flow applications using fluorous spacer technology. The benchtop continuous flow microwave described allows sequential processing of multiple plugs using small amounts of reagents for reaction optimization, scale-up and array synthesis. The system features online monitoring of temperature, pressure and microwave power. Several different reactions have been scaled up, including a Suzuki−Miyaura cross-coupling reaction and nucleophilic substitutions. In all cases it was possible to optimize the reaction conditions on a small scale (∼300 μL processing volume), and achieve similar conversions on an intermediate scale (∼30 mL), offering the potential for further scale-up without modifying the optimized conditions (direct scalability) producing similar isolated yields in the C−C bond formation reaction.
Setup and preliminary results of a pilot on-line cable PD monitoring system on an 11 kV switchboard using capacitive couplers (2010)

In today's competitive power transmission and distribution (T&D) industry the need for predictive and scheduled maintenance of the infrastructure has become a vital necessity. On-line condition monitoring of underground cables and switchboards for the dominant failure mechanism of Partial Discharge (PD) has been in use for some time now. It has been shown that on-line measurements for monitoring the activity and the degradation severity of the PD can not be calibrated in terms of their charge (pC). Although the direct interpretation of the measured voltage gives some indication, for more profound results specific locations have to be monitored over time to record the evolution of the amplitude and/or phase shift (trending). For these reasons a pilot on-line cable monitoring system is currently being implemented in a substation of the Electricity Authority of Cyprus (EAC) on selected breakers of the 11 kV switchboard. This system will alleviate the need for the physical presence of expert personnel on site, as measurements from sensors that will be non-invasively installed will automatically be recorded and processed on a continuous basis thus allowing potential dangerous PD events to be captured. Furthermore, the proposed system will implement permanent capacitive couplers that offer better sensitivity compared to other sensors. In this paper the setup and calibration of these sensors, together with some preliminary results will be presented. (4 pages)
A scheduling scheme for multiplexing of VBR sources in digital TV systems (2003)

Digital TV transmission systems allow a transmission channel to be shared by a number of sources. In order to improve the bandwidth utilization, variable bit rate encoding and statistical multiplexing techniques are usually used. However, the channel sharing requires a careful scheduling method for multiplexing. This is because the video and audio materials have to be presented at the receivers at specific points in time. In this paper, we present a novel scheduling scheme for statistical multiplexing of VBR sources. Our method is sensitive to the timing requirements of the sources and sends the packets as close to their transmission deadlines as possible. The advantages of our method are: (1) it decreases the broadcast deadline violation probability (or improves the bandwidth utilization), (2) it minimizes the delay and delay jitter of packets and (3) it generates a transport stream compliant with all the standard TV receivers. Simulations were conducted to compare our algorithm with the first-come-first-serve scheduling method. The results show that our algorithm significantly reduces both the percentage of dropped packets (by 35%-50%) and the average packet delay.
Trinucleotide repeat expansion and DRPLA (Smith`s disease): Molecular characterization of atrophin-1 (1994)

Smith`s disease (also known as dentatorubral pallidoluysian atrophy or DRPLA) is a rare, progressive, fatal neuropsychiatric disorder similar to Huntington`s disease (HD). Smith`s disease is characterized by ataxia, choreoathetosis, myoclonic epilepsy, dementia, and genetic anticipation. Neuropathological findings include prominent cell loss in the dentate nucleus of the cerebellum, the globus pallidus, the red nucleus, and the subthalamic nucleus. An expansion of a CAG trinucleotide repeat encoding polyglutamine in a gene originally identified in our laboratory as part of a program to clone candidate genes for disorders with anticipation has recently been found to cause this disorder. We have identified two families that demonstrate the pathological and genetic features (expanded CAG repeat and anticipation) of this disease. Northern analysis indicates that the gene, which we have termed atrophin-1, is widely expressed as a 5 kb mRNA in normal human brain and peripheral tissues. Brain expression is highest in the cerebellum. The developmental expression of the rat homologues of IT-15 (the gene in which a CAG expansion causes HD) and atrophin-1 were compared. Atrophin-1 was most highly expressed in early rat embryo brain (E16), whereas the greatest expression of IT-15 was in the adult rat brain. Cloning and sequencing of the openmore » reading frame from inserts contained in brain cDNA libraries is in progress. In addition to the CAG repeat, the ORF contains an unusual region of alternating acidic and basic amino acids. Further characterization of atrophin-1, and comparison of it to other genes in which trinucleotide repeat expansion leads to neuropsychiatric disorders, should lead to a better understanding of the pathophysiology by which CAG repeat expansion causes human disease.« less
Activity of trospectomycin against Bacteroides fragilis and other Bacteroides species (1988)

The in vitro activity of trospectomycin (U-63366; 6'-n-propyl spectinomycin pentahydrate sulfate) was evaluated against 189 clinical isolates of the Bacteroides fragilis group and 65 Bacteroides species isolates. At less than or equal to 8 micrograms/ml, the activity of trospectomycin compared favorably with those of clindamycin and cefoxitin against B. fragilis, Bacteroides distasonis, and Bacteroides vulgatus, and there was no cross resistance to these three drugs among the strains of the B. fragilis group. All the Bacteroides species were susceptible to trospectomycin. The results of this in vitro study indicate that trospectomycin possesses excellent activity against Bacteroides species.
Development of gaze detection system for multiple users - Toward realization of an intelligent service interface - (2009)

This paper reports the development of a reliable vision-based eye-gaze detection system for an analysis of multiple users' intention and communication. Headgear design for the gaze detection, a recording system, an off-line computation, an algorithm of the gaze extraction, and its calibration method, are mentioned. Applying the proposed system to a test case, sufficient precision of the gaze detection was confirmed.
Design of a Numbering-up System of Monolithic Microreactors and Its Application to Synthesis of a Key Intermediate of Valsartan (2016)

Synthesis of a key intermediate of valsartan was accomplished using five parallel monolithic microreactors connected to a split-and-recombine-type flow distributor. The channel resistances of the flow distributor were designed so as to minimize the flow maldistribution among reactors by using pressure drop compartment model, which is analogous to electrical resistance network.
Signature of surface states on NMR chemical shifts: A theoretical prediction (1999)

We show with an ab initio calculation that electronic surface states have a strong effect on NMR chemical-shift spectra. For the hydrogen-chemisorbed diamond (111) surface, we find that the atomic layers close to the surface experience a variation of the chemical shift, which is proportional to the density of empty surface states. This effect could be used as a direct probe of the surface-state density profile, by measuring experimentally the NMR chemical shift resolved for each atomic layer.
Inhibition of mitogen‐activated protein kinase 1/2 in the acute phase of stroke improves long‐term neurological outcome and promotes recovery processes in rats (2015)

It is demonstrated that benefits of early treatment with U0126 persist beyond subacute phase of ischaemic stroke in male rats. Prevention of ERK1/2 activation in the acute phase results in improved long-term functional outcome and enhances later-stage recovery processes. These results expand our understanding of the benefits and promise of using MEK1/2 inhibitors in stroke recovery.
The alkaline and antibacterial effect of seven Ca(OH)<sub>2</sub>liners in vitro (1984)

The alkaline effect of seven Ca(OH)2 liners was studied, using extractions with unbuffered 0.9% NaCl solutions and buffered bacterial growth media. The antibacterial effect was studied by cultivating Streptococcus mutans in the presence of liner specimens. All liners made the NaCl solutions strongly alkaline (pH > 10), although MPC® and Reolite® released much less Ca than did Dycal®, Life®, Procal®, Renew®, and Reocap-E®. The weaker alkaline effect of MPC and Reolite was shown by the extractions with the growth media. Consequently, these two liners were not able to prevent the growth of Str. mutans. No growth was observed in the presence of the other five liners, and the media remained alkaline during the 12-h incubation period, Regrowth of the bacteria grown in the presence of these effective liners showed that only Dycal could be considered bactericidal, whereas the four other liners acted bacteriostatically.
The Role of Drugs in Workplace Injuries: Is Drug Testing Appropriate? (1995)

In the past decade, many employers have adopted drug-testing programs to reduce workplace injuries. However, little scientific evidence shows that drug use is a significant and substantial cause of total workplace injuries. The purpose of this study was to empirically assess the role of drugs and alcohol in causing workplace injuries. Questionnaires were received from 882 Ontario employees in a household survey. Results showed that many variables were significantly related to job injuries. The variables were ranked according to the relative importance of each variable's contribution to total job injuries. Alcohol problems, licit drug use, and illicit drug use ranked 7, 11, and 12 respectively among a group of 12 significant variables. In order to examine the likelihood that drug use was a cause of job injuries, the relationship between job injuries and alcohol problems, licit drug use, and illicit drug use was examined across categories of third variables. For age, the relationship between drug use and injuries remained strong for the youngest age group, but disappeared for the oldest age group. Logistic regression analysis confirmed the plausibility of noncausal explanations of job injuries for illicit drug use, but not for alcohol problems or licit drug use. Overall, the results indicated that illicit drug use does not appear to be a major cause of job injuries. The implications of these results for drug-testing programs are discussed.
2,3‐Dihydroxy‐3‐{3‐[3‐(trifluoromethyl)diazirin‐3‐yl]phenyl}propionic Acid. A Cleavable Carbene‐Generating Reagent Used for Photocrosslinking (1992)

Abstract The synthesis of 2,3‐dihydroxy‐3‐{3‐[3‐(trifluoromethyl)diazirin‐3‐yl]phenyl}propionic acid ( 8 ), a new cleavable carbenegenerating reagent used in photocrosslinking experiments in molecular biology is described. This synthesis starts with the bromination of trifluoroacetophenone. The resulting compound 2 is converted into the corresponding diazirine 6 via oxime 3 , O ‐tosyloxime 4 , and diaziridinyl 5 derivatives. The cleavable cis ‐diol bond is formed via a cinnamic acid derivative 7 by permanganate oxidation resulting in the title compound 8 .
Periovulatory Endocrine Events in the Stumptailed Monkey (Macaca arctoides)* (1980)

Blood samples were obtained frequently from stumptailed monkeys (Macaca arctoides) at midcycle and assayed for FSH, LH, 17 beta-estradiol, and progesterone. Periovulatory endocrine events were generally similar to those which have been described in rhesus monkeys and women. Although the midcycle patterns of estradiol in individual monkeys appeared quite varied, careful evaluation indicated the following general characteristics: 1) a plateau or transient decline in estradiol 30-44 h before the LH peak, 2) a sharp rise in serum estradiol before the initiation of the LH rise, 3) a diminution in serum concentrations or a decline in the rate of estradiol increase at the initiation of the LH rise, and 4) an elevation in estradiol at the time of the highest serum LH value. The first elevation in serum progesterone occurred 0-12 h before the LH peak and after the initiation of the LH surge. An unusual finding was a second midcycle rise in serum FSH, which occurred 2-3 days after the LH peak in 10 of 13 menstrual cycles. The biological significance of this second FSH rise in stumptailed monkeys is not known with certainty, but available evidence suggests that it enhances postovulatory progesterone and estrogen syntheses. Two methods are presented for the RIA of serum FSH in the stumptailed macaque.
Stem Cell Transplantation for Refractory Crohn Disease (2016)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Bambusurils – Receptors for Organic Anions (2013)

Bambusurils are an interesting, growing family of anionic
receptors. They are formed by an acid-catalyzed and templated
condensation reaction from glycoluril and formaldehyde. These
cheap building blocks form a rigid yet still sufficiently
flexible structure ideal for the supramolecular interactions.1
Since the publication of the first bambusuril, several other
members differing by the substitution and size were prepared.
Depending on the substitution it is possible to tune its
properties such as solubility or its supramolecular affinities.
It is well established, that six-membered bambusurils are
capable of forming complexes with wide variety of inorganic
anions, but recently we found out, that some of them are even
able to interact with organic ones.
Revisión crítica de la utilización del método del gradiente conjugado y extensiones en la minimización de funciones nolineales con condiciones (1984)

En este trabajo se efectúa una revisión de la aplicación del método del gradiente conjugado (diseñado para resolver sistemas de ecuaciones lineales) a la optimización de funciones no lineales (no cuadráticas) en el conjunto factible definido por condiciones lineales. Se describen las desventajas de su utilización; se sugiere su sustitución por algoritmos que, precisando parecida capacidad de memoria, no adolecen de sus inconvenientes. Los resultados computacionales que se acompañan avalan esta sustitución
Enzymatic Amplification of the Human Immunodeficiency Virus in Peripheral Blood Mononuclear Cells from Pediatric Patients (1989)

The presence of the human immunodeficiency virus type 1 (HIV) provirus was assessed in peripheral blood mononuclear cells (PBMCs) from 27 offspring of HIV-infected mothers, 12 of these mothers, and 4 HIV-uninfected mother-infant control pairs. Enzymatic amplification of specific conserved regions of the gag and env genes was performed directly in PBMC lysates using the polymerase chain reaction (PCR) technique. The enzymatically amplified gene products were evaluated using the oligomer hybridization detection procedure. PBMCs from infected infants (as determined by Centers for Disease Control clinical criteria) and from HIV-infected mothers manifested a characteristic HIV oligomer hybridization product. Clinically uninfected seropositive infants with declining HIV antibody titers and infants who became seronegative lacked an enzymatically amplified HIV gene product. These preliminary data indicate that PCR is a valuable diagnostic technique to detect or exclude HIV infection in young infants and children.
Computational materials design of negative effective<i>U</i>system in hole-doped chalcopyrite CuFeS<sub>2</sub> (2014)

A general rule of negative effective U(U(eff)) system caused by (i) exchange correlation and (ii) charge excitation mechanisms is proposed. Based on the general rule, we perform ab initio electronic structure calculations by generalized gradient approximation (GGA) + U method for hole-doped chalcopyrite CuFeS2 [Cu(+)(d(10))Fe(3+)(d(5))S(2-)(s(2)p(6))2]. It is found from our calculations that the hole-doped CuFeS2 has the negative U(eff) = -0.44 eV, where U(eff) ≡ E(N + 1) + E(N - 1) - 2E(N) < 0 and E(N) is the total energy of the hole-doped CuFeS2. The negative U(eff) is caused by the charge-excitation in the hole-doped Cu(2+)(d(9)) and S(-)(s(2)p(5)), and also caused by the exchange-correlation in the hole-doped Fe(4+)(d(4)). The strong attractive electron-electron interaction (U(eff) = -0.44 eV ∼ -5000 K) originates from the purely electronic mechanism. The closed shell of the d(10) electronic configuration is more stable than the d(9) electronic configuration, since the first excited state with the d(9)s(1) electronic configuration and the ground state with the d(10) electronic configuration are very close, then these two states repel very strongly through the second order perturbation. Therefore, the spin-polarized total energy curve for the hole-doped CuFeS2 shows the strong upward convexity with N - 1, N and N + 1 electronic configurations leading to the negative U(eff). The hole-doped paramagnetic and metallic CuFeS2 with the negative U(eff) may cause a possible high-Tc superconductor (Tc ∼ 1000 K, if 2Δ/kBTc ≈ 10 by assuming a strong coupling regime) because of the strong attractive electron-electron interactions (superconducting gap Δ ≈ |U(eff|) ∼ 5000 K). Finally, we propose a new computational materials design methodology to design ultra high-Tc superconductors by using three steps starting from the atomic number only.
Vibrational Raman optical activity in (R)-(+)-3-methylcyclopentanone: experimental and ab initio theoretical studies (1993)

No abstract available.
Domino Addition/N-C Heterocyclization of Azides with Allenyl Magnesium Bromide: Rapid Synthesis of 5-Butynyl-1,2,3-triazoles (2007)

1,5-Disubstituted 1,2,3-triazoles are formed through a novel domino reaction involving the addition of aromatic azides to an excess of allenylmagnesium bromide with concomitant N-C heterocyclization followed by the addition of another mole of allenylmagnesium species to generate the terminal acetylenic product in moderate to high yields.
Overconfidence and Occupational Choice (2016)

A statistical theory of overconfidence is proposed and applied to the issue of occupational choice. Individuals who can choose whether to engage in an activity or not must estimate their performance. The estimates have error and that error has positive expectation among those who engage in the activity. As a result, an unbiased ex ante estimate of performance in an occupatoin results in an ex post biased estimate of ability among those enter. The statistical theory of overconfidence provides a number of testable implications, most significant of which is that overconfidence should be more prevalent in occupations where estimates of ability are noisier. This and other implications are tested and found to hold using the Current Population Survey and Panel Study of Income Dynamics data.