gebhart/patrepeval huggingface dataset:
Design principles behind Chiron: a UIMS for software environments (1988)

User interface facilities are a crucial part of the infrastructure of a software environment. The authors discuss the particular demands and constraints on a user interface management system (UIMS) for a software environment, and the relation between the architecture of the environment and the UIMS. A model for designing user interface management systems for large, extensible environments is presented. This model synthesizes several recent advances in user interfaces and specializes them to the domain of software environments. The model can be applied to a wide variety of environment contexts. A prototype implementation is described. >
Effect of Extracorporeal Membrane Oxygenation on Leukocyte Function in Neonates (1991)

The impact of extracorporeal membrane oxygenation (ECMO) on neonatal leukocyte content and function was examined in six patients. Patients were treated with ECMO for a mean of 134 h (range 44-246 h). Absolute neutrophil counts decreased from 14679 +/- 2291/mm3 to 7791 +/- 1672/mm3 after 2 h of ECMO. However, neutrophil phagocytosis and oxidative burst remained unchanged during the first 48 h of bypass. Monocyte counts also decreased during bypass, and at times were undetectable in 50% of patients. Monocyte HLA-DR content was decreased compared to normal cord blood prior to initiation of ECMO, and remained low throughout ECMO. However, the content increased significantly after termination of bypass. Plasma C3a levels increased transiently, paralleled by an increase in neutrophil CR3 expression. While moribund infants had some impairment of host defenses prior to ECMO, there was no further impact of ECMO per se on the parameters measured, other than transient complement activation and decreased monocyte counts.
Did Office Market Size Matter in the 1980s? A Time‐Series Cross‐Sectional Analysis of Metropolitan Area Office Markets (1992)

Recent contributions to the literature have resulted in a standard modelling of office markets. The models provide considerable insight into the working of office markets. • Nonetheless, a major difficulty is the use of data for a single city or aggregate data for the U.S. The latter implicitly assumes that model structure is invariant across cities. In this article we test for structural differences in office markets by size class. Rental data from REIS Reports for twenty‐one metropolitan areas for the time period 1981 to 1990 are used to model office market behavior. Results suggest market outcomes vary by city size, larger markets are better modelled using standard procedures, and Manhattan behaves quite differently from the other markets.
Hormonal changes in exfoliated normal buccal mucosal cells (2013)

Age-related alterations are observed in buccal smears.
Data-Dimensionality Reduction Using Information-Theoretic Stepwise Feature Selector (2009)

A novel information-theoretic stepwise feature selector (ITSFS) is designed to reduce the dimension of diesel engine data. This data consist of 43 sensor measurements acquired from diesel engines that are either in a healthy state or in one of seven different fault states. Using ITSFS, the minimum number of sensors from a pool of 43 sensors is selected so that eight states of the engine can be classified with reasonable accuracy. Various classifiers are trained and tested for fault classification accuracy using the field data before and after dimension reduction by ITSFS. The process of dimension reduction and classification is repeated using other existing dimension reduction techniques such as simulated annealing and regression subset selection. The classification accuracies from these techniques are compared with those obtained by data reduced by the proposed feature selector.
High rate capability of a BaTiO<sub>3</sub>-decorated LiCoO<sub>2</sub> cathode prepared via metal organic decomposition (2016)

Abstract Metal organic decomposition (MOD) using octylic acid salts was applied to synthesize a BaTiO 3 –LiCoO 2 (BT–LC) composite powder. The Ba and Ti octylates were utilized as metal precursors, in an attempt to synthesize homogeneous BT nanoparticles on the LC matrix. The BT–LC composite, having a phase-separated composite structure without any impurity phase, was successfully obtained by optimizing the MOD procedure. The composite prepared using octylate precursors exhibited a sharper distribution and better dispersibility of decorated BT particles. Additionally, the average particle size of the decorated BTs using metal octylate was reduced to 23.3 nm, compared to 44.4 nm from conventional processes using Ba acetate as well as Ti alkoxide as precursors. The composite cathode displayed better cell performance than its conventional counterpart; the discharge capacity of the metal octylate-derived specimen was 55.6 mAh/g at a 50C rate, corresponding to 173% of the capacity of the conventional specimen (32.2 mAh/g). The notable improvement in high rate capability obtained in this study, compared with the conventional route, was attributed to the higher density of the triple junction formed by the BT–LC–electrolyte interface.
Tuning for Performance and Stability in Systems of Nearly Tautochronic Torsional Vibration Absorbers (2010)

This paper considers the dynamic response and performance characteristics of a special class of centrifugal pendulum torsional vibration absorbers. The absorbers of interest are designed by selection of the path that their center of mass follows, such that their dynamics are linear or nearly so, out to large amplitudes of motion, thereby avoiding the nonlinear-induced detuning that typically accompanies such responses. These order-tuned, tautochronic or isochronic, absorbers have been the subject of previous investigations, including analyses of the synchronous and certain nonsynchronous responses of systems comprised of a set of identical absorbers. The analysis and experiments have demonstrated that the synchronous response of such absorber systems can experience an instability that results in nonsynchronous responses in which a subset of absorbers have significantly larger amplitude than the corresponding synchronous response. In this study, we present results that generalize these stability results to include absorbers whose dynamics differ slightly from tautochronic by varying the absorber path such that both linear and nonlinear perturbations of perfect tuning are included. It is shown by analysis and verified by simulations that the perfect tuning case is quite special, specifically that the instability described above occurs for tunings very close to ideal and that the synchronous response can be made stable over the entire feasible operating range by employing small levels of linear and/or nonlinear detuning. Such detuning is known to have the additional benefit of resulting in smaller absorber responses and an attendant larger operating range albeit at the expense of absorber performance in terms of attenuating rotor torsional vibrations. The main conclusion of these results is that one can select a very small amount of detuning to avoid this undesirable instability and that such detuning does not have a significant effect on absorber effectiveness. The analytical results derived also provide a quantitative means of predicting synchronous absorber response amplitudes and the associated rotor torsional vibration levels, as well as the stability properties of these responses, results are very useful for the design of absorber systems.
Ammonia as Alkali for Alkaline/Surfactant/Polymer Floods (2015)

Summary Ammonia is logistically preferred over sodium carbonate for alkaline/surfactant/polymer (ASP) enhanced-oil-recovery projects because of its low molar mass and the possibility for it to be delivered as a liquid. On an offshore platform, space and weight savings can be the determining factor in deciding whether an ASP project is feasible. Logistics may also be critical in determining the economic feasibility of projects in remote locations. Ammonia as alkali together with a surfactant blend of alkyl propoxy sulfate/internal olefin sulfonate (APS/IOS) functions as an effective alkali. Surfactant adsorption is low, and oil recovery in corefloods is high. Static adsorption tests show that low surfactant adsorption is attained at pH &gt;9, a condition that ammonia satisfies at low solution concentration. It is expected that ammonia has a performance deficiency relative to sodium carbonate in that it does not precipitate calcium from solution. Calcium accumulation in the ammonia ASP solution will occur, caused by ion exchange from clays. The high oil recovery for ammonia and the calcium accumulation in ASP and surfactant/polymer corefloods with APS/IOS blends show that this surfactant system is effective and calcium-tolerant. Also, phase behavior and interfacial-tension (IFT) measurements suggest that APS/IOS blends remain effective in the presence of calcium. Ethylene oxide/propylene oxide sulfates (such as the used APS) are known commercially available, calcium-tolerant surfactants. However, because of hydrolysis, sulfate-type surfactants are suitable for use only in lower-temperature reservoirs. Very different behavior was noticed for phase-behavior measurements with calcium-intolerant surfactants such as alkyl benzene sulfonates and IOS. In this case, calcium addition results in a very high IFT and complete separation of oil and brine. Presumably, this will result in low oil recovery. A preferred approach for ASP offshore with divalent-ion-intolerant surfactants may be the use of a hybrid alkali system combining the attributes of sodium carbonate and ammonia. The concept is to supply the bulk of the alkalinity for an ASP flood by ammonia with all the inherent logistical advantages. A minor quantity of sodium carbonate is added to the formulation to specifically precipitate calcium ions.
Rapid prototyping of an automated video surveillance system: a hardware-software co-design approach (2011)

FPGA devices with embedded DSP and memory blocks, and high-speed interfaces are ideal for real-time video processing applications. In this work, a hardware-software co-design approach is proposed to effectively utilize FPGA features for a prototype of an automated video surveillance system. Time-critical steps of the video surveillance algorithm are designed and implemented in the FPGAs logic elements to maximize parallel processing. Other non timecritical tasks are achieved by executing a high level language program on an embedded Nios-II processor. Pre-tested and verified video and interface functions from a standard video framework are utilized to significantly reduce development and verification time. Custom and parallel processing modules are integrated into the video processing chain by Altera's Avalon Streaming video protocol. Other data control interfaces are achieved by connecting hardware controllers to a Nios-II processor using Altera's Avalon Memory Mapped protocol.
Schools and Schooling (2011)

Abstract Even after Constantine legitimized Christianity in 313 (by the Edict of Milan), it did not introduce any new forms or subjects of teaching or contents different from the subjects taught in pre‐Christian schools. Pagan and Christian boys (to a lesser extent girls) attended the same schools, learned the same subjects and had the same teachers. A good secular education was necessary for success as a civil servant. Religious education was left to the mothers.
Connection between myocardial oedema, inflammation and function during sepsis: role of alpha1 AMP-activated protein kinase (2013)

Purpose: Induced capillary leakage contributes to organ dysfunction during sepsis. However, the contribution of cardiac oedema to sepsis-induced left ventricular dysfunction remains to be clarified. In addition, signalling pathways controlling the sepsis-induced myocardial oedema has not been identified. Since AMP-activated protein kinase (AMPK) has been shown to control endothelial cytoskeleton and to display anti-inflammatory effects, we postulated that AMPK-activation influenced vascular permeability and inflammation during sepsis even in the heart and could modulate heart function during severe sepsis.

Methods: Sepsis was triggered by a sublethal dose of lipopolysaccharide (LPS, 10 mg.kg-1) injection inducing systolic left ventricular dysfunction. Wild-type (a1+/+) mice were compared to α1AMPK knock-out (α1-/-). In vivo vascular permeability was evaluated by dye extravasation. Left ventricular mass, oedema and function were studied by echocardiography and magnetic resonance imaging (MRI). Lung neutrophil deposition and myeloperoxydase activity were quantified. Cytokines expression were measured in heart tissue with quantitative RT-PCR. Plasmatic cytokines were measured by cytometric bead array.

Results: LPS injection resulted in an increased systemic inflammatory cytokines production (TNFα, IL1β, IL6, CXCL1, RANTES) whereas no difference was observed between α1+/+ and α1-/- mice. Similarly, acute lung injury after LPS (characterized by neutrophil accumulation and myeloperoxidase activity in the lung) did no differ between a1+/+ and α1-/- animals. By contrast, α1-/- exhibited a dramatic increased in the LPS-induced vascular hyperpermeability as well as LPS-induced cytokines expression (TNFα, IL1β, IL6, CXCL1-2) in the heart. Echocardiography revealed an increase in LV mass 24 h after LPS injection in α1-/-. MRI definitely demonstrated that increased LV mass corresponded to exaggerated LV wall oedema. LPS injection induced a transient decrease in LV systolic function as assessed by ejection fraction (EF) which mainly occurred after 6 hours. Despite the more pronounced wall oedema in α1-/-, no difference in systolic function could be detected between α1+/+ and α1-/- at 6 and 24 hours after LPS.

Conclusions: Our results showed for the first time a signalling pathway controlling LV wall oedema during sepsis. AMPK exerts a protective action against myocardial inflammation and LPS- induced oedema. Interestingly, exaggerated LV wall oedema and inflammation is not associated with aggravated systolic dysfunction. However, it could contribute to diastolic dysfunction observed in septic patients.
Characterization of leukotriene A4 synthase from murine mast cells: evidence for its identity to arachidonate 5-lipoxygenase. (1986)

Leukotriene A4 synthase was purified from the cytosolic fraction of murine mast cells. The enzyme converted 5-hydroperoxy-6-trans-8,11,14-cis-icosatetraenoic acid (5-HPETE) to leukotriene A4. This unstable product was identified by demonstration of two epimers of 6-transleukotriene B4, methanol trapping, as well as further transformation to leukotriene B4 by leukotriene A4 hydrolase. Leukotriene A4 synthase stereospecifically eliminated the D-hydrogen at C-10 (pro-R) in the synthesis of leukotriene A4 when incubated with [10D-3H;3-(14)C]5-HPETE. The purified enzyme also exhibited 5-lipoxygenase activity toward arachidonic acid and 8-lipoxygenase activity towards 8,11,14-cisicosatrienoic acid. All of these activities required Ca2+ and ATP for their maximal velocities. The effects of heat treatment and of several lipoxygenase inhibitors on these enzyme activities as well as coelution in various chromatographic systems strongly suggest that lipoxygenase and leukotriene A4 synthase activities reside in the same enzyme molecule.
MC3T3-E1 Cell Assay on Collagen or Fibronectin Immobilized Poly (Lactic Acid-ε-Caprolactone) Film (2015)

In the present study, collagen (Coll) or fibronectin (FN) was immobilized onto poly(lactic acid)/ε-caprolactone (PLCL) copolymer surface and the attachment and proliferation of osteoblast-like cells on Coll or FN immobilized PLCL (Coll-PLCL, FN-PLCL) were evaluated. Coll or FN immobilized PLCL was prepared through a condensation reaction between the carboxylic acid groups on the hydrolyzed PLCL (PLCL-COOH) surface and the amino groups of Coll or FN using water soluble carbodiimide. The contact angle of the PLCL-COOH, Coll-PLCL and FN-PLCL surfaces with respect to double distilled water significantly decreased compared with PLCL (p<0.05). Number of attached cells onto Coll-PLCL or FN-PLCL films was significantly greater than on PLCL films from at the time of 90 min to 7days (p<0.05). The morphological differences of attached osteoblast-like cells were observed between PLCL films and Coll-PLCL or FN-PLCL films at the early stage of cell assay. The cell attached on Coll-PLCL and FN-PLCL films appeared more flat than on PLCL films. Additionally, many actin filaments and stress fibers were observed on Coll-PLCL or FN-PLCL films during 3 and 7 days of cell assay. Actin filaments and stress fibers were few on PLCL films. These data demonstrated the effectiveness of collagen and fibronectin immobilization of PLCL for cell attachment and proliferation. This indicates that collagen or fibronectin immobilization of PLCL films was effective for biological activities of osteoblast-like cells.
DNA : protein interactions and gene regulation (1987)

This book contains 24 chapters. Some of the chapter titles are: Interaction of Steroid Hormone Receptors with DNA; Specific DNA-Binding Proteins and DNA Sequences Involved in Steroid Hormone Regulation of Gene Expression; DNA Sequences Required for Steroid Hormone Regulation of Transcription; Topisomerase II-DNA Complexes: Novel Targets of Antineoplastic Drug Action; and RNA-Protein Interactions in the Nuclear Ribonucleoprotein Particles.
Analyseur spatial de faisceau laser à réglage automatique (2014)

Un analyseur de la distribution d'intensité spatiale d'un faisceau laser focalisé ou transmis par une fibre optique comprend: une lentille de mise en forme; un dispositif pour prélever un échantillon partiel du faisceau; un dissipateur de chaleur; une photodiode; une lentille de formation d'image pour former des images de l'avion sur un capteur d'image; une motorisation de la lentille de mise en forme pour traduire le long de l'axe optique; une motorisation de la lentille de formation d'image à traduire dans un plan perpendiculaire à l'axe optique; une motorisation du capteur d'image à translation le long de l'axe optique; une unité électronique de commande chaque motorisation; une unité électronique de synchronisation du capteur d'image, connecté à la photodiode pour synchroniser la capture d'image avec les impulsions laser ou à impulsions; une unité électronique de réglage de l'ouverture et / ou le gain du capteur d'image; et une interface de logiciel de pilotage et le paramétrage des unités de commande électroniques, équipé d'une unité de traitement d'image.
Pierre Rain. L'Europe et la restauration des Bourbons, 1908 (1909)

Muret Pierre. Pierre Rain. L'Europe et la restauration des Bourbons, 1908. In: Revue d'histoire moderne et contemporaine, tome 13 N°1,1909. pp. 98-100.
ChemInform Abstract: INTRAMOLECULAR PHOTOCYCLOADDITION REACTION IN THE 2‐(4‐PENTENYL)‐5‐ARYL‐SUBSTITUTED TETRAZOLE SYSTEM (1983)

Abstract 5‐Phenyltetrazol (Ia) wird zu (Ib) und (Ic) substituiert.
Diagnostic and Prognostic Value of [<sup>18</sup>F]Fluorodeoxyglucose Positron Emission Tomography for Recurrent Head and Neck Squamous Cell Carcinoma (2002)

PET was a highly sensitive method of detecting recurrent HNSCC and provided important prognostic information for relapse-free and overall survival.
Structural and Metal Binding Characterization of the C-Terminal Metallochaperone Domain of Membrane Fusion Protein SilB from <i>Cupriavidus metallidurans</i> CH34 (2011)

Detoxification of heavy metal ions in Proteobacteria is tightly controlled by various systems regulating their sequestration and transport. In Cupriavidus metallidurans CH34, a model organism for heavy metal resistance studies, the sil determinant is potentially involved in the efflux of silver and copper ions. Proteins SilA, SilB, and SilC form a resistance nodulation cell division (RND)-based transport system in which SilB is the periplasmic adaptor protein belonging to the membrane fusion protein (MFP) family. In addition to the four domains typical of known MFPs, SilB has a fifth additional C-terminal domain, called SilB(440-521), which is characterized here. Structure and backbone dynamics of SilB(440-521) have been investigated using nuclear magnetic resonance, and the residues of the metal site were identified from (15)N- and (13)C-edited HSQC spectra. The solution structure and additional metal binding experiments demonstrated that this C-terminal domain folds independently of the rest of the protein and has a conformation and a Ag(+) and Cu(+) binding specificity similar to those determined for CusF from Escherichia coli. The small protein CusF plays a role in metal trafficking in the periplasm. The similarity with CusF suggests a potential metallochaperone role for SilB(440-521) that is discussed in the context of simultaneous expression of different determinants involved in copper resistance in C. metallidurans CH34.
Flexible AlN flags for efficient wind energy harvesting at ultralow cut-in wind speed (2015)

Flexible AlN for better harvesting of wind power at low wind speed.
Timed Inhibition of Orexin System by Suvorexant Improved Sleep and Glucose Metabolism in Type 2 Diabetic db/db Mice (2016)

Sleep disturbances are associated with type 2 diabetes; therefore, the amelioration of sleep may improve metabolic disorders. To investigate this possibility, we here examined the effects of suvorexant, an antiinsomnia drug targeting the orexin system, on sleep and glucose metabolism in type 2 diabetic mice. Diabetic db/db mice had a longer wakefulness time during the resting period, as compared with nondiabetic db/m+ control mice. The single or 7-day administration of suvorexant at lights-on (ie, the beginning of the resting phase) increased nonrapid eye movement sleep time during the resting phase and, as a consequence, reduced awake time. The daily resting-phase administration of suvorexant for 2-4 weeks improved impaired glucose tolerance in db/db mice without affecting body weight gain, food intake, systemic insulin sensitivity, or serum insulin, and glucagon levels. No changes were detected in the markers of lipid metabolism and inflammation, such as the hepatic triglyceride content and Tnf-α mRNA levels in liver and adipose tissues. The improving effect of suvorexant on glucose tolerance was associated with a reduction in the expression levels of hepatic gluconeogenic factors, including phosphoenolpyruvate carboxykinase and peroxisome proliferator-activated receptor-γ coactivator-1α in the liver in the resting phase. In contrast, the daily awake-phase administration of suvorexant had no beneficial effect on glucose metabolism. These results suggest that the suvorexant-induced increase of sleep time at the resting phase improved hepatic glucose metabolism in db/db mice. Our results provide insight into the development of novel pharmacological interventions for type 2 diabetes that target the orexin-operated sleep/wake regulatory system.
On detecting and modeling deterministic drift in long run sequences of tapping data (1999)

Abstract In tapping experiments, a subject attempts to tap continuously at a specified tempo. It is of interest to psychologists to study how well the subject can maintain the starting tempo, and in particular, whether the tempo tends to drift towards attractor tempos specified by a model suggested by rhythm researchers. This paper focuses on the analysis of a new data set of long run sequences of tapping data, applying rank tests to test tor drift specified by the attractor model, estimatingthe point at which the final tempo is achieved. and analyzing the amount and direction of drift. Keywords: Rank testchange-pointrhythm dataaitracior tempooscillator signature