gebhart/patrepeval huggingface dataset:
A Method for Standardizing the Biacetyl Content of Creamed Cottage Cheese (1959)

The addition of 0.15% citric acid to creamed cottage cheese held at 45 F. did not increase the biaeetyI content; whereas, addition of Streptococc~,s citrovorus gave a slight increase and addition of both citric acid and S. citrovorns gave still more of an increase. No biacetyl was formed in a 12% fat cremning mixture containing S. citrovorus or S. c#rororus plus 0.15% citrie acid. Considerable biaeetyl was produced in a creaming mixture containing large numbers of S. cit,roror.t,s after it was adjusted to pH 4.2 with citric acid and held at 70 F. Cottage cheese creamed with such a preparation had a high initial biacetyl content.
DFT+U Study of Polaronic Conduction in Li<sub>2</sub>O<sub>2</sub> and Li<sub>2</sub>CO<sub>3</sub>: Implications for Li–Air Batteries (2013)

The main discharge products formed at the cathode of nonaqueous Li–air batteries are known to be Li2O2 and residual Li2CO3. Recent experiments indicate that the charge transport through these materials is the main limiting factor for the battery performance. It has been also shown that the performance of the battery decreases drastically when the amount of Li2CO3 at the cathode increases with respect to Li2O2. In this work, we study the formation and transport of hole and electron polarons in Li2O2 and Li2CO3 using density functional theory (DFT) within the PBE+U approximation. For both materials, we find that the formation of polarons (both hole and electron) is stabilized with respect to the delocalized states for all physically relevant values of U. We find a much higher mobility for hole polarons than for the electron polarons, and we show that the poor charge transport in Li2CO3 compared to Li2O2 can be understood through a polaronic model for the conduction. Furthermore, the hole polaronic model in Li2O2 provides a possible explanation for the experimentally observed preferential growth direction of the films. Our results also suggest that doping is unlikely to be a viable route for improving the transport properties of Li2O2 or Li2CO3.
Mechanisms of neuronal adaptation to ethanol. Ethanol induces Hsc70 gene transcription in NG108-15 neuroblastoma x glioma cells (1991)

The mechanisms underlying neuronal adaptation to ethanol are poorly understood but appear to involve alterations in cellular membrane structure and/or function. Using a two-dimensional gel analysis, we have recently identified Hsc70 as an ethanol-responsive gene (Miles, M.F. (1989) Neurology 39, (Suppl. 1), 425). Hsc70 is a constitutive member of the 70-kDa stress protein family which plays an important role in protein trafficking and coated vesicle processing. Thus, modulation of Hsc70 by ethanol could produce widespread changes in cellular membrane functioning. Here, we report a detailed study on the regulation of Hsc70 by ethanol in NG108-15 neuroblastoma x glioma cells. Northern and Western blot analyses showed that ethanol concentrations observed in actively drinking alcoholics caused an induction of Hsc70 mRNA and protein. Increases in Hsc70 mRNA were seen as early as 4 h after exposure to ethanol. In comparison with ethanol, propanol and butanol caused proportionally greater increases in Hsc70 mRNA. This is consistent with known anesthetic and intoxicating potencies of these aliphatic alcohols and suggested that lipophilicity, rather than an osmotic effect, was critical for ethanol induction of Hsc70. Induction of Hsc70 mRNA by ethanol resulted, at least in part, from increased Hsc70 gene transcription as determined by nuclear runoff studies. Stable transfection analysis revealed an ethanol-responsive cis-acting element in the proximal 2500 base pairs of the Hsc70 promoter. Regulation of Hsc70 by 50-200 mM ethanol appeared to be a specific change in expression of an ethanol-responsive gene rather than a typical stress protein response since no induction of the highly inducible stress protein, Hsp70, was seen at these ethanol concentrations. These results suggest that ethanol-induced changes in Hsc70 transcription may be important for neuronal adaptation to ethanol and the development of tolerance and dependence in alcoholics.
Self-Amplifying RNA Viruses as RNA Vaccines (2020)

Single-stranded RNA viruses such as alphaviruses, flaviviruses, measles viruses and rhabdoviruses are characterized by their capacity of highly efficient self-amplification of RNA in host cells, which make them attractive vehicles for vaccine development. Particularly, alphaviruses and flaviviruses can be administered as recombinant particles, layered DNA/RNA plasmid vectors carrying the RNA replicon and even RNA replicon molecules. Self-amplifying RNA viral vectors have been used for high level expression of viral and tumor antigens, which in immunization studies have elicited strong cellular and humoral immune responses in animal models. Vaccination has provided protection against challenges with lethal doses of viral pathogens and tumor cells. Moreover, clinical trials have demonstrated safe application of RNA viral vectors and even promising results in rhabdovirus-based phase III trials on an Ebola virus vaccine. Preclinical and clinical applications of self-amplifying RNA viral vectors have proven efficient for vaccine development and due to the presence of RNA replicons, amplification of RNA in host cells will generate superior immune responses with significantly reduced amounts of RNA delivered. The need for novel and efficient vaccines has become even more evident due to the global COVID-19 pandemic, which has further highlighted the urgency in challenging emerging diseases.
Optical dividers for quadrant avalanche photodiode detectors (1991)

Quadrant avalanche photodiodes (QAPDs) cannot be made with a perfect transition region. We are pursuing development of several optical divider approaches to narrow the effective transition region of the RCA Juction-side divided QAPD, a superior device except that it has no response in the transition region. This divider will maximize the slope factor and minimize optical losses. Optical divider approaches include the total internal reflection prism divider, the etched silicon reflective divider, and the binary optics quadrant divider. The nature and progress of this work and the test results are reported.
RESENHA CRÍTICA DO LIVRO “NEOLIBERALISMO – DESMONTE DO ESTADO SOCIAL”, DE PLAUTO FARACO DE AZEVEDO (2019)

RESENHA CRITICA DO LIVRO “NEOLIBERALISMO – DESMONTE DO ESTADO SOCIAL”, DE PLAUTO FARACO DE AZEVEDO
Reaction of Sugars with 2‐Hydrazinopyridine, Precursors for Seco C‐Nucleosides of 1,2,4‐Triazolo[4,3‐a]pyridine. (2004)

Abstract For Abstract see ChemInform Abstract in Full Text.
An Economical Tandem Multiplex Real-Time PCR Technique for the Detection of a Comprehensive Range of Respiratory Pathogens (2009)

This study used real-time PCR assays to screen small sample volumes for a comprehensive range of 35 respiratory pathogens. Initial thermocycling was limited to 20 cycles to avoid competition for reagents, followed by a secondary real-time multiplex PCR. Supplementary semi-nested human metapneumovirus and picornavirus PCR assays were required to complete the acute respiratory pathogen profile. Potential pathogens were detected in 85 (70%) of pernasal aspirates collected from 121 children with acute respiratory symptoms. Multiple pathogens were detected in 29 (24%) of those samples. The tandem multiplex real-time PCR was an efficient method for the rapid detection of multiple pathogens.
Knowledge management and the politics of knowledge: illustrations from complex products and systems (2001)

While there is an increasing recognition of the social character of knowledge in segments of the literature on knowledge management, this paper argues that there has been a limited engagement with issues surrounding the politics of knowledge. There is now a well-established critique of technically-led knowledge management practices in which knowledge is treated in passive, objectivised, and static terms. A key element of this critique concerns the limits of codification strategies directed at making tacit knowledge explicit. This is founded upon an interpretative conceptualisation of inter-subjective understanding as always provisional, incomplete, and embedded in contexts of social action. While sympathetic to this position, it is argued that there is more to considering knowledge practices than the problem of understanding. Shared understanding, where participants to an interaction achieve a satisfactory interpretation of their respective positions, in no way implies mutual agreement about the validity of these positions. Drawing on insights from Habermas about models of social action and knowledge-guiding interests, we offer a series of concepts encouraging sensitivity to the relationship between knowledge, power, and interests. Aspects of the argument are then illustrated with case examples drawn from research into organisational knowledge in companies producing and using complex products and systems.
<i>In Vitro</i> Analyses of the Effects of Heparin and Parabens on Candida albicans Biofilms and Planktonic Cells (2011)

Infections and thromboses are the most common complications associated with central venous catheters. Suggested strategies for prevention and management of these complications include the use of heparin-coated catheters, heparin locks, and antimicrobial lock therapy. However, the effects of heparin on Candida albicans biofilms and planktonic cells have not been previously studied. Therefore, we sought to determine the in vitro effect of a heparin sodium preparation (HP) on biofilms and planktonic cells of C. albicans. Because HP contains two preservatives, methyl paraben (MP) and propyl paraben (PP), these compounds and heparin sodium without preservatives (Pure-H) were also tested individually. The metabolic activity of the mature biofilm after treatment was assessed using XTT [2,3-bis-(2-methoxy-4-nitro-5-sulfophenyl)-2H-tetrazolium-5-carboxanilide] reduction and microscopy. Pure-H, MP, and PP caused up to 75, 85, and 60% reductions of metabolic activity of the mature preformed C. albicans biofilms, respectively. Maximal efficacy against the mature biofilm was observed with HP (up to 90%) compared to the individual compounds (P < 0.0001). Pure-H, MP, and PP each inhibited C. albicans biofilm formation up to 90%. A complete inhibition of biofilm formation was observed with HP at 5,000 U/ml and higher. When tested against planktonic cells, each compound inhibited growth in a dose-dependent manner. These data indicated that HP, MP, PP, and Pure-H have in vitro antifungal activity against C. albicans mature biofilms, formation of biofilms, and planktonic cells. Investigation of high-dose heparin-based strategies (e.g., heparin locks) in combination with traditional antifungal agents for the treatment and/or prevention of C. albicans biofilms is warranted.
Providing Adaptive Courses in Learning Management Systems with Respect to Learning Styles (2007)

Learning management systems (LMS) are commonly used in e-learning but provide little, or in most cases, no adaptivity. However, courses which adapt to the individual needs of students make learning easier for them and lead to a positive effect in learning. In this paper, we introduce a concept for providing adaptivity based on learning styles in LMS. In order to show the effectiveness of our approach, Moodle was extended by an add-on and an experiment with 437 students was performed. From the analysis of the students’ performance and behaviour in the course, we found out that students who learned from a course that matches their learning styles spent significantly less time in the course and achieved in average the same marks than students who got a course that either mismatched with their learning styles or included all available learning objects. Therefore, providing adaptive courses in LMS according to the proposed concept can be seen as effective in supporting students in learning.
CONTINUOUS FLOW SEPARATION, AN APPLICATION OF SELECTIVE MAGNETOSEDIMENTATION (1984)

A Continuous Flow Separation (CFS) technique is introduced, which operates uninterruptedly, without the use of a magnetic filter matrix. CFS is based on selective magnetosedimentation, in a field gradient introduced by the processing magnet itself. A laboratory scale continuous flow system has been developed and tested for several types of slurries. Results will be given for a variety of experimental parameters using a test suspension.
Efficient HRTF Interpolation in 3D Moving Sound (2002)

This paper addresses efficient interpolation of Head-Related Transfer Functions (HRTFs) for binaural generation of moving sound. Aiming at computational complexity reduction, the authors have recently proposed a new method for HRTF interpolation based on auxiliary Inter-positional Transfer Functions (IPTFs). The present paper reviews this IPTF-based method and focuses on IPTF design, which employs tools such as balanced model reduction and spectral smoothing to compute a complete set of reduced-order IPTFs. The interpolation scheme based on these reduced-order IPTFs is computationally more efficient and yields results perceptually comparable to those attainable by the bilinear method, which uses the HRTFs directly. Therefore, the proposed method is promising for real-time generation of spatial sound.
Analysis of a transport protocol based on rateless erasure correcting codes (2010)

This paper presents a protocol designed as an alternative to classical TCP for channels which experience high loss-rates. The protocol is simplified with respect to TCP by eliminating the need of retransmissions and the associated buffers. This is achieved by applying a rateless erasure correcting code to the data that is going to be transferred. A modified version of the TCP congestion control algorithms is used in order to better differentiate between losses caused by errors on the channel and losses caused by congestion in the network. A statistical model for the steady-state throughput of the protocol is included in the paper as well. Using simulations performed in ns-2 the throughput model is validated. Other aspects of the behavior of the protocol are also investigated. The results are promising, mainly showing that the protocol does not experience any significant performance degradation in terms of steady-state throughput, even if the loss rate on the channel is high.
Digital pen with multi-purpose mouse functionality (2016)

This thesis report is submitted in partial fulfillment of the requirements for the degree of Bachelor of Science in Electrical and Electronic Engineering, 2016.
Standard x-ray diffraction powder patterns : (1971)

From Introduction: This report presents information for 63 compounds (40 experimental and 23 calculated patterns), and is the nineteenth of the series of Standard X-ray Diffraction Powder Patterns.
[Penetration of calcium hydroxide based cements by dental enamel conditioning acids]. (1990)

It was verified the penetration of phosphoric acid into 3 commercial calcium hydroxide-based cements (Life, Renew and Prisma VLC Dycal). The colorimetric method employed permitted the identidication of phosphorus amount in representative samples of 6 successive layers 0.1 mm thick of each material. The acid etching used were the commercial products Scotchbond Etching Gel--3M at 36.114% by weight and Solução Condicionadora--Johnson & Johnson at 36.054% by weight. The contact time was 60 seconds. The result showed that layers 0.1 mm tick for Life and Prisma VLC Dycal and 0.2 mm thick for Renew were able to block the penetration of phosphoric acid solution whereas layers 0.1 mm thick for the 3 cements were able to block the penetration of phosphoric acid gel.
Implementation of Successive Approximate Register typed A/D Converter for a Monitored Battery Voltage Conversion (2011)

In this paper, a design and an implementation of an Analog to Digital (A/D) converter are introduced for the conversion of monitored battery cell voltage in the cell voltage monitoring(CVM) system in battery management system(BMS), which is one of the key devices of ECO hybrid cars. The A/D converter in CVM system required a middle conversion speed and a high resolution, therefore, a successive approximate register(SAR) typed A/D converter with 10 bits resolution has been designed and implemented using Magna 0.6um 40V process. The measurement result which kept LSB accuracy in the full scale range(FSR) of 5V, showed the usefulness of the SAR typed A/D converter in realizing a CVM system.
How to Display Search Results in Digital Libraries - User Study. (2003)

Information retrieval systems display search results by various methods. This paper focuses on a model for displaying a list of search results by means of textual elements that utilize a new information unit that replaces the currently used information unit. This paper includes a short description of several studies that support the model. The results of the research show that we can improve effectiveness of using search results list by displaying the lines in context instead of first lines of documents. Adding optional data components such as key words and category can improve even better the effectiveness of the search.
Enzymatic Characterization and Functional Domain Mapping of Brain Myosin-V (1996)

The actin binding and ATPase properties, as well as the functional domain structure of chick brain myosin-V, a two-headed, unconventional myosin, is reported here. Compared to conventional myosin from skeletal muscle, brain myosin-V exhibits low K-EDTA- and Ca-ATPase activities (1.8 and 0.8 ATP/s per head). The physiologically relevant Mg-ATPase is also low (approximately 0.3 ATP/s), unless activated by the presence of both F-actin and Ca2+ (Vmax of 27 ATP/s). Ca2+ stimulates the actin-activated Mg-ATPase over a narrow concentration range between 1 and 3 microM. In the presence of saturating Ca2+ and 75 mM KCl, surprisingly low concentrations of F-actin activate the Mg-ATPase in a hyperbolic manner (KATPase of 1.3 microM). Brain myosin-V also binds with relatively high affinity (compared to other known myosins) to F-actin in the presence of ATP, as assayed by cosedimentation. Digestion of brain myosin-V with calpain yielded a 65-kDa head domain fragment that cosediments with actin in an ATP-sensitive manner and a 80-kDa tail fragment that does not interact with F-actin. The 80-kDa fragment results from cleavage one residue beyond the proline-, glutamate-, serine-, threonine-rich region. Our data indicate that the Mg-ATPase cycle of brain myosin-V is tightly regulated by Ca2+, probably via direct binding to the calmodulin light chains in the neck domain, which like brush border myosin-I, results in partial (approximately 30%) dissociation of the calmodulin associated with brain myosin-V. The effect of Ca2+ binding, which appears to relieve suppression by the neck domain, can be mimicked by calpain cleavage near the head/neck junction.
Walking assistant device with GPS and electronic compass (2008)

A knowledge of the 'proteome,' total protein output encoded by a genome, provides information on (1) if and when predicted gene products are translated, (2) the relative concentrations of gene products, and (3) the extent of posttranslational modification, none of which can be accurately predicted from the nucleic acid sequence alone. The current status of proteome analysis is reviewed with respect to some of the techniques employed, automation, relevance to genomic studies, mass spectrometry and bioinformatics, limitations, and recent improvements in resolution and sensitivity for the detection of protein expression in whole cells, tissues, or organisms. The concept of 'proteomic contigs' is introduced for the first time. Traditional approaches to genomic analysis call upon a number of strategies to produce contiguous DNA sequence information, while 'proteomic contigs' are derived from multiple molecular mass and isoelectric point windows in order to construct a picture of the total protein expression within living cells. In higher eukaryotes, the latter may require several dozen image subsets of protein spots to be stitched together using advanced image analysis. The utility of both experimental and theoretical peptide-mass fingerprinting (PMF) and associated bioinformatics is outlined. A previously unknown motif within the peptide sequence of Elongation Factor Tu from Thermus aquaticus was discovered using PMF. This motif was shown to possess potential significance in maintaining structural integrity of the entire molecule.
Canine and feline dirofilariasis: life cycle, pathophysiology, and diagnosis. (2008)

Infection with the intravascular parasite Dirofilaria immitis is an increasingly recognized problem in domestic dogs and cats. Heartworm infection is preventable; however, once an animal is infected, heartworm disease and potentially life-threatening complications can develop. An understanding of the heartworm life cycle and transmission season, the limitations of testing methods, and the clinical signs of heartworm disease is necessary to provide clients with appropriate information regarding prevention and treatment of heartworm infection in their pets.
Mechanism of action of pentagastrin and acetylcholine on the longitudinal muscle of the canine antrum. (1975)

1. Electrical and mechanical activities of the longtitudinal muscle of the dog antrum were recorded with the double sucrose‐gap technique. 2. The muscle exhibited spontaneous action potentials which consisted of a spike‐like potential which, after a brief and partial repolarization, was followed by a negative‐going, plateau‐type potential. In 97% of the preparations, no tension changes were produced by spontaneous action potentials. 3. Tetrodotoxin, atropine, alpha‐ and beta‐adrenoceptor antagonists, and H1 and H2 receptor blocking agents had no effect on the action potential. It was concluded that the action potential was myogenic in origin. 4. The mean frequency of the action potential at 37+/‐ 0.5 degrees C was 1.0/min+/‐0.06 (s.e. of mean, n=92) and the mean duration 7.1+/‐0.2 sec (s.e. of mean, n=11). 5. Steady depolarizing current increased whereas hyperpolarizing current decreased the frequency of the action potential. 6. Length‐tension relations were studied. In twelve strips, the average resting, passive, tension at LO was 570 mg. The active force of isometric contraction produced by acetylcholine increased with strip length up to a maximum, then decreased wtih further increased in length. There were no mechanical responses to pentagastrin. 7. Pentagastrin had two sites of action. On smooth muscle, it increased the frequency of the action potential in a dose dependent fashion. Threshold concentraions ranged from 2X10‐14 to 10‐11M. The ED50 was 2X10‐10M. The maximum response, 5.4/min, was reached at 10‐8M. Pentagastrin also released acetylcholine from intramural cholinergic nerves. 8. Pentagastrin reduced the amplitude and duration of the action potential.
A test for evolutionary equilibria: Phanerozoic brachiopods and Cenozoic mammals (1977)

The fossil record of Phanerozoic brachiopod genera and Late Cenozoic New World mammal genera is examined for evidence of evolutionary equilibria. One necessary (but insufficient) condition is met: within temporal intervals, numbers of originations correlate with numbers of extinctions. Eliminating temporally short-ranging brachiopods, however, reduces the correlation so that it explains only 16% of the variation. More decisive tests of the equilibrium hypothesis appear impossible with available data. Difficulties of temporal and geographic scale, taxonomic level, and ecological consistency must be resolved before equilibrium models can be applied in paleontology for other than inspiration.