gebhart/patrepeval huggingface dataset:
A Mass-Sensitive Approach for the Detection of Anaesthetic Xenon* (2011)

Quartz crystal microbalances (QCMs) were utilized for the detection of the noble gas xenon (Xe) by combining them with different recognition layers such as permethylated calixarenes (tetramethyl-tert-butylcalix[4]arene (Cal4Me), hexamethyl-tert-butylcalix[6]arene (Cal6Me)), and polyurethanes, with covalently embedded Cal4OH (Poly4Cal), or Cal6OH (Poly6Cal). A third type of sensitive material is synthesized from polyacrylic acid (PAA) and polyvinyl alcohol (PVA) and utilized as a sensitive coating. The results demonstrate that the Cal4Me layer gives higher response towards Xe, while, by the use of a second uncoated QCM channel, the influence of ambient humidity could be nearly completely compensated by signal subtraction. Moreover, the Cal4Me sensor shows excellent reversibility and rapid response time, providing a potentially reliable way to determine Xe during anaesthesia.
A Frequency Synthesizer for Television Receivers (1974)

Recently, several new approaches to the design of television tuning systems have emerged. Federal regulations concerning equal parity for UHF and VHF tuning systems have caused increased interest in purely electronic tuning systems. In addition, such factors as reliability, economics, aesthetics and convenience, as well as the increased number of channels on UHF and cable, have spurred interest in the development of solid state, totally electronic television tuning capability. The ideal tuning system incorporates all of these features.
Otologic and audiologic manifestations of hutchinson‐gilford progeria syndrome (2011)

HGPS is caused by a mutation in the LMNA gene resulting in the production of an abnormal nuclear protein; this in turn affects nuclear structure and function. Patients with HGPS have characteristic otologic features due to cartilaginous and subcutaneous tissue abnormalities and typically demonstrate low-frequency conductive hearing loss despite largely normal tympanometry. It is important to be aware of these conditions in managing these patients.
The internal politics of the firm (1998)

Political activity in society at large arises inevitably from the twin facts that individuals and groups have varying interests and that the institutions of societal decision making provide channels through which to pursue those interests. Political activity within the firm has similar roots. Workers and managers, lenders and stockholders, suppliers, customers, and local communities are all potentially affected in varying ways by a firm’s decisions, and all have means to influence many of those decisions. As in the public sector, groups often organize to advance the group members’ shared interests. Workers may be represented by unions, stockholders by a board of directors, customers by users groups, lenders by creditors’ committees, local communities by their governments and regulatory bodies, and so on. All parties have access to the courts in case of contract disputes.
Information technology. Level 2. BTEC First (2010)

El programa BTEC es un programa de estudios que permite obtener una cualificación profesional o laboral. Este recurso está preparado para ayudar al alumno en el curso BTEC First, nivel 2, sector profesional tecnología de la información y se divide en diez unidades: la comunicación en la industria de las TI;trabajar en la industria de las TI; sistemas informáticos; personalización del software; creación de una red informática; sistemas de base de datos; desarrollo de sitios web; gráficos por ordenador y desarrollo de los juegos de ordenador. Incluye actividades de evaluación en cada unidad que cubren todos los criterios de ésta para ofrecer a los estudiantes la oportunidad de practicar sus tareas y profundizar en el conocimiento y la comprensión de la materia.
The adsorption of diethyldithiophosphate on cuprous sulphide (1984)

Abstract The adsorption of diethyldithiophosphate (DTP) from its aqueous solutions has been studied on cuprous sulphide (chalcocite) surfaces by measuring the characteristic changes in the positions and relative integrated intensities of C 1s, P 2p, S 2p, O 1s and Cu 2p 3/2 XPS lines and by observing the changes in the in situ internal reflection IR (infrared) spectra at various stages of adsorption. A multistage model is suggested for DTP adsorption on a freshly formed chalcocite surface. During adsorption components preadsorbed on the surface are removed. The DTP ions are initially distributed on the surface without any special orientation but later form islands. The degree of orientation increases with coverage and later, a well oriented close packed monolayer is found. When the adsorption continues beyond this stage the additionally deposited molecules form a randomly oriented layer on the close packed oriented monomolecular layer.
Delayed relaxation in thin-film heads (1989)

The delayed relaxation after writing with a Permalloy thin-film head has been studied experimentally. The phenomenon of delayed relaxation is shown to be caused predominantly by stress-induced relaxation of the flux closure domains along the edges of the thin-film-head yoke. It is necessary for this effect that the composition of the Permalloy yields nonzero magnetostriction. The fairly rapid temperature change directly after write will then trigger irreversible wall displacements which show up as transient noise pulses in the head output. Depending on the actual edge domain relaxation, these transients can have a positive or a negative polarity, or can be bipolarity transients. This thermomechanically triggered irreversible wall-motion process can fairly accurately be modeled as a Poisson process. The model predicts the arrival time distribution, the probability of occurrence for different write currents, and threshold settings reasonably well. This 'noise-after-write' effect can be made smaller by striving for zero magnetostriction and a lower write power dissipation, and to some extent by increasing the thermal conductivity to the slider.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
VaROT: Methodology for Variation-Tolerant DSP Hardware Design Using Post-Silicon Truncation of Operand Width (2011)

With increasing parameter variations in nanoscale technologies, computational blocks in Digital Signal Processing (DSP) hardware become increasingly vulnerable to variation-induced delay failures. These failures can significantly affect the Quality of Service (QoS) for a DSP chip leading to degradation in parametric yield. Existing post-silicon calibration and repair approaches, which rely on adaptation of circuit operating parameters such as voltage, frequency or body bias, typically incur large delay or power overhead in order to maintain QoS. In this paper, we present a novel low overhead approach of healing DSP chips by commensurately truncating the operand width based on its process corner. The proposed approach exploits the fact that critical timing paths in DSP data paths typically originate from the least significant bits (LSBs). This condition can also be satisfied by skewing the path delay distribution during logic synthesis or gate sizing. Hence, truncation of the LSBs, realized by setting them at constant values, can effectively reduce the delay of a unit, thereby avoiding delay failures. We also note that truncation of LSBs typically has minimal impact on QoS. Besides, efficient choice of truncation bits and values can minimize the impact on QoS. We propose appropriate design time modifications including insertion of low-overhead truncation circuit and gate sizing to maximize the delay improvement with truncation. Simulation results for a Discrete Cosine Transform (DCT) application at 45nm technology show large improvement in yield (41.6%) with up to 5X savings in power compared to existing healing approaches.
A pH-dependent Structural Transition in the Homopurine-homopyrimidine Tract in Superhelical DNA (1985)

We have inserted the 509-bp-long fragment of sea urchin P. miliaris histone gene spacer region into plasmid pUC19. The fragment contains the 60-bp-long homopurine-homopyrimidine tract that is known to be hypersensitive to the S1 endonuclease. Using two-dimensional gel electrophoresis we have observed a sharp structural transition in the insert with increasing DNA superhelicity. As in the cases of cruciform and Z form formation, the observed transition partly relaxes the superhelical stress. In contrast with the other two well documented transitions, the observed transition strongly depends on pH. At pH7 and above the transition occurs at negative superhelicities exceeding the physiological range (- sigma greater than 0.08). For pH6 the transition occurs at -sigma = 0.055, whereas for pH4.3 it takes place at -sigma = 0.001. A comprehensive analysis of the obtained data has made it possible to define the nature of the observed transition. We conclude that under superhelical stress or/and at low pH homopurinehomopyrimidine tracts adopt a novel spatial structure called the H form.
Employment of Adaptive Learning Techniques for the Discrimination of Acoustic Emissions. (1983)

Under Phase I of this contract, several new acoustic emission techniques were developed. These techniques showed a promise as a means of adaptively learning and removing multimode and multipath effects from acoustic emission signals in a preprocessing step prior to source characterization. In this Phase II effort, software was developed to implement the techniques, and a series of experiments was carried out to assess the effectiveness and practicality of these techniques on real signals. Analysis of the data revealed that reasonably accurate transfer functions could be determined adaptively, when a flat response wide-band transducer was employed, and when relatively short record lengths were used. Available commercial transducers with the requisite frequency response are quite fragile, however, and far too insensitive for practical use. Pattern recognition techniques were also explored as a means of characterizing acoustic emission sources; specifically, details of the pulse microstructure were examined for evidence of characterizable features. No such evidence was found in either raw (reverberation dominated) or processed data. Originator-supplied keywords include: Acoustic emission, Digital signal processing, Adaptive learning, Homomorphic deconvolution. (Author).
Discovery of 4-Amino-5-(3-bromophenyl)-7-(6-morpholino-pyridin- 3-yl)pyrido[2,3-<i>d</i>]pyrimidine, an Orally Active, Non-Nucleoside Adenosine Kinase Inhibitor (2001)

Adenosine (ADO) is an endogenous homeostatic inhibitory neuromodulator that reduces cellular excitability at sites of tissue injury and inflammation. Inhibition of adenosine kinase (AK), the primary metabolic enzyme for ADO, selectively increases ADO concentrations at sites of tissue trauma and enhances the analgesic and antiinflammatory actions of ADO. Optimization of the high-throughput screening lead, 4-amino-7-aryl-substituted pteridine (5) (AK IC50 = 440 nM), led to the identification of compound 21 (4-amino-5-(3-bromophenyl)-7-(6-morpholino-pyridin-3-yl)pyrido [2,3-d]pyrimidine, ABT-702), a novel, potent (AK IC50 = 1.7 nM) non-nucleoside AK inhibitor with oral activity in animal models of pain and inflammation.
ChemInform Abstract: Enhanced Synthetic Efficiency Towards Natural Products via Transition Metal Catalyzed Reactions. (1995)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Dynamic behaviour of ECAP-processed aluminium at room and sub-zero temperature (2008)

Dynamic behavior of ultrafine-grained (UFG) commercially pure aluminum (AA1070) samples prepared via two different equal-channel angular pressing (ECAP) routes was studied at high strain rates at room and sub-zero temperatures using the Hopkinson Split Bar technique, and at quasi-static strain rates at room temperature using a servohydraulic materials testing machine. For comparison, similar tests were also conducted on coarse-grained AA1070 aluminum samples. 3D- and 2D-ECAP dies were used to deform the initial coarse-grained aluminum to total equivalent plastic strains of ca. 10 using routes Bc and C+Bc, respectively. The ECAP processing increased the strength of the material substantially but at the same time reduced its strain hardening capability. After initial yielding, strain softening took place in all studied UFG materials at quasi- static strain rates, but at high strain rates (above 103 s-1) notable strain hardening was observed. Strain hardening was further enhanced by sub-zero temperatures, at least at high strain rates. The microstructures of the ultrafine-grained and coarse-grained materials were investigated prior to and after the compression tests using a transmission electron microscope. Increased dislocation activity at high strain rates and at sub-zero temperatures suggests dislocation mediated plasticity still to play a substantial role in the deformation of the studied ultrafine-grained materials.
Studies on L-Ascorbic Acid Derivatives. II. L-Ascorbic Acid 3-Phosphate and 3-Pyrophosphate (1969)

Phosphorylation of 5, 6-isopropylidene-L-ascorbic acid with phosphorus oxychloride gave mainly a mixture of four phosphates. Column chromatography on Dowex-1-bicarbonate with a solution of sodium bicarbonate as a developer was found suitable for the separation of these phosphates for the preparative purpose. Consequently, L-ascorbic acid 3-phosphate and 3-pyrophosphate were isolated as the magnesium salts. Treatment of the former with diazomethane, followed by successive amidation and ozonization gave methyl oxamate, and this provided evidence that the starting ester was the 3-phosphate. The latter ester, on treatment with acid or alkali, afforded quantitatively the same product, i.e., L-ascorbic acid 3-phosphate. These facts, together with the elemental analysis and potentiometric analysis, determined the structure of the latter to be L-ascorbic acid 3-pyrophosphate.
Review of deuterium–tritium results from the Tokamak Fusion Test Reactor (1995)

After many years of fusion research, the conditions needed for a D–T fusion reactor have been approached on the Tokamak Fusion Test Reactor (TFTR) [Fusion Technol. 21, 1324 (1992)]. For the first time the unique phenomena present in a D–T plasma are now being studied in a laboratory plasma. The first magnetic fusion experiments to study plasmas using nearly equal concentrations of deuterium and tritium have been carried out on TFTR. At present the maximum fusion power of 10.7 MW, using 39.5 MW of neutral-beam heating, in a supershot discharge and 6.7 MW in a high-βp discharge following a current rampdown. The fusion power density in a core of the plasma is ≊2.8 MW m−3, exceeding that expected in the International Thermonuclear Experimental Reactor (ITER) [Plasma Physics and Controlled Nuclear Fusion Research (International Atomic Energy Agency, Vienna, 1991), Vol. 3, p. 239] at 1500 MW total fusion power. The energy confinement time, τE, is observed to increase in D–T, relative to D plasmas, by 20% and the ni(0) Ti(0) τE product by 55%. The improvement in thermal confinement is caused primarily by a decrease in ion heat conductivity in both supershot and limiter-H-mode discharges. Extensive lithium pellet injection increased the confinement time to 0.27 s and enabled higher current operation in both supershot and high-βp discharges. Ion cyclotron range of frequencies (ICRF) heating of a D–T plasma, using the second harmonic of tritium, has been demonstrated. First measurements of the confined alpha particles have been performed and found to be in good agreement with TRANSP [Nucl. Fusion 34, 1247 (1994)] simulations. Initial measurements of the alpha ash profile have been compared with simulations using particle transport coefficients from He gas puffing experiments. The loss of alpha particles to a detector at the bottom of the vessel is well described by the first-orbit loss mechanism. No loss due to alpha-particle-driven instabilities has yet been observed. D–T experiments on TFTR will continue to explore the assumptions of the ITER design and to examine some of the physics issues associated with an advanced tokamak reactor.
Hexokinase receptor complex in hepatoma mitochondria: evidence from N,N'-dicyclohexlycarbodiimide-labeling studies for the involvement of the pore-forming protein VDAC (1986)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTHexokinase receptor complex in hepatoma mitochondria: evidence from N,N'-dicyclohexlycarbodiimide-labeling studies for the involvement of the pore-forming protein VDACRichard A. Nakashima, Patrick S. Mangan, Marco Colombini, and Peter L. PedersenCite this: Biochemistry 1986, 25, 5, 1015–1021Publication Date (Print):March 11, 1986Publication History Published online1 May 2002Published inissue 11 March 1986https://pubs.acs.org/doi/10.1021/bi00353a010https://doi.org/10.1021/bi00353a010research-articleACS PublicationsRequest reuse permissionsArticle Views310Altmetric-Citations168LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Multicenter Trial in North America of Urolume Urinary Sphincter Prosthesis (1994)

We investigated the effectiveness and associated complications of treatment with an endoluminal urethral sphincter prosthesis in 153 spinal cord injury men (mean age 36 years, range 16 to 74 years) with urodynamically diagnosed detrusor-external sphincter dyssynergia. These patients were prospectively treated with a urethral sphincter stent at 15 centers in North America. Followup ranged from 2 to 33 months. Voiding pressures averaged 76 +/- 28, 42 +/- 21, 44 +/- 38, 35 +/- 18 and 32 +/- 20 cm. water, respectively, before prosthesis insertion in 153 patients and at 3 months in 123, 6 months in 114, 12 months in 98 and 24 months in 22. A significant decrease in voiding pressure was noted in the 22 patients at 24 months compared with matched preoperative data (80 +/- 25 cm. water, p = 0.03). The residual urine decreased from 181 +/- 154 ml. before insertion to 82 +/- 93 ml. at 24 months (p = 0.01). Maximum cystometric capacity remained constant, with a mean of 195 +/- 158 ml. before insertion to 248 +/- 122 ml. at 24 months (p = 0.17). No significant differences were apparent after 24 months of followup in any of the urodynamic parameters between 44 patients with and 109 without previous external sphincterotomy. Hemorrhage requiring blood transfusion, obstructive hyperplastic epithelial overgrowth and soft tissue erosion did not occur. No deleterious effects were observed on renal or erectile function. Of the patients 43 (28.1%) required 2 prostheses to bridge the external sphincter completely. Stent removal was required in 10 patients. Seven explantations were required for prosthesis migration, 1 for pain and urethral edema, 1 for inability to maintain a condom catheter, and 1 for nonepithelialization and secondary bladder neck obstruction. A total of 13 patients (8.5%) required a subsequent operation for bladder neck obstruction. Therefore, the sphincter prosthesis is an attractive modality for the treatment of external sphincter dyssynergia in patients with and without previous external sphincterotomy because of its ease of deployment and minimal associated morbidity.
Three Seinura species from Japan with a description of S. shigaensis n. sp. (Tylenchomorpha: Aphelenchoididae) (2021)

A preliminary survey of Seinura spp. was conducted in the Kyoto area, Western Japan. The survey yielded four new strains of Seinura spp., including two strains of S. caverna, a strain of S. italiensis, and a strain of an undescribed species. Molecularly, the two strains of S. caverna were nearly identical to the type strain but showed some minor variations, particularly in the mitochondrial cytochrome oxidase subunit I gene. The small subunit and D2-D3 large subunit sequences of the Japanese strain of S. italiensis were nearly identical and identical to its original description, respectively, and the difference in the small subunit was due to mis-reading of the sequences. The new species, S. shigaensis n. sp., was phylogenetically close to S. caverna and S. persica, although these three species were clearly different phylogenetically. The new species was typologically similar or nearly identical to several other Seinura spp., including S. chertkovi, S. christiei, S. italiensis, S. steineri, and S. tenuicaudata, but it can be distinguished from those species by the morphometric values. Because the new species is phylogenetically very close to S. caverna, it could be a good comparative system for S. caverna as a potential satellite model for the predatory nematode.
Alignment features for micro-optical interconnect modules (2003)

We report on the design, fabrication and characterization of micro-alignment features for a free-space multi-channel intra-chip micro-optical interconnect module. The features will be used for the alignment of the micro-optical module with respect to a 64x64 interleaved VCSEL/Detector array chip, ensuring the lateral and longitudinal alignment tolerances needed for high transmission efficiencies and low cross-talk on the optical channels. The features are fabricated with our in-house Deep Lithography with Protons technology. We also present our work on the characterization tools needed to assess the quality of the alignment features.
Combined Positron Emission Tomography and Magnetic Resonance Imaging Scanners—Potential Neurological Applications (2008)

Recently, there has been great interest in combining positron emission tomography (PET) and magnetic resonance imaging (MRI), and a number of integrated scanners capable of simultaneous acquisition have been developed and successfully tested in small animal 1,2 and human 3 imaging.
Molecular Evidence for Lysogeny in Lactobacillus acidophilus and Characterization of a Temperate Bacteriophage (1990)

Thirty-five strains of Lactobacillus acidophilus were examined for the presence of inducible bacteriophage. Treatment of L. acidophilus CFMll, CFM12, and CFMl3 with .12 J.lg/ml mitomycin C resulted in inductive lysis. Lysates contained structurally complete phage particles with isometric heads and long concentrically banded tails. Phage lysates exhibited no activity against 31 strains of L. acidophilus and 9 strains of eight additional Lactobacillus species. Thirty putative phage-free variants of L. acidophilus CFMll were obtained. Lysates containing phage lall inhibited all variants but did not plaque on any of them. The genome of temperate phage lall showed homology with the genomes of the parental strain, L. acidophilus CFMll, and 20 noninducible variants but not those of five prophage-cured variants. The buoyant density of phage lall was 1.43 g/cm 3 . Treatment of the phage lall genome with restriction endonucleases indicated that it was double stranded DNA. Agarose gel electrophoresis of uncut and restricted lall DNA indicated a molecular size of 45 to 48 kb.