gebhart/patrepeval huggingface dataset:
Quantitation of isobaric phosphatidylcholine species in human plasma using a hybrid quadrupole linear ion-trap mass spectrometer (2016)

Phosphatidylcholine (PC) species in human plasma are used as biomarkers of disease. PC biomarkers are often limited by the inability to separate isobaric PCs. In this work, we developed a targeted shotgun approach for analysis of isobaric and isomeric PCs. This approach is comprised of two MS methods: a precursor ion scanning (PIS) of mass m/z 184 in positive mode (PIS m/z +184) and MS<sup>3</sup> fragmentation in negative mode, both performed on the same instrument, a hybrid triple quadrupole ion-trap mass spectrometer. The MS<sup>3</sup> experiment identified the FA composition and the relative abundance of isobaric and sn-1, sn-2 positional isomeric PC species, which were subsequently combined with absolute quantitative data obtained by PIS m/z +184 scan. This approach was applied to the analysis of a National Institute of Standards and Technology human blood plasma standard reference material (SRM 1950). We quantified more than 70 PCs and confirmed that a majority are present in isobaric and isomeric mixtures. The FA content determined by this method was comparable to that obtained using GC with flame ionization detection, supporting the quantitative nature of this MS method. This methodology will provide more in-depth biomarker information for clinical and mechanistic studies.
L'agriculture périurbaine : analyse d'une marginalité (Suburban agriculture : analysis of a marginal phenomenon) (1994)

Là où la pression urbaine est la plus forte, l'agriculture est en marge. Elle ne relève plus vraiment du système rural de production territoriale, elle est trop en dépendance à l'intérieur du système urbain. Elle est menacée au sein d'un espace périurbain trop convoité. Le maintien d'une agriculture périurbaine passe par l'affirmation de celle-ci au sein d'un nouveau système territorial dont la cohérence tient à la place acquise par l'agriculture.
Far-infrared absorption by shallow donors in multiple-well GaAs-<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mrow><mml:msub><mml:mrow><mml:mi mathvariant="normal">Ga</mml:mi></mml:mrow><mml:mrow><mml:mn>1</mml:mn><mml:mi mathvariant="normal">−</mml:mi><mml:mi mathvariant="normal">x</mml:mi></mml:mrow></mml:msub></mml:mrow></mml:math><mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mrow><mml:msub><mml:mrow><mml:mi mathvariant="normal">Al</mml:mi></mml:mrow><mml:mrow><mml:mi mathvariant="normal">x</mml:mi></mml:mrow></mml:msub></mml:mrow></mml:math>As heterostructures (1986)

We report the results of calculations of multiple-well effects upon the energies of shallow donors and their influence upon far-infrared absorption profiles. We have calculated the binding energies of the ground and first few excited states for a variety of well and barrier widths and magnetic field strengths. For a uniform donor distribution the profiles show several peaks, the strongest corresponding to transitions to excited states of donors located near the center of a barrier. Significantly weaker peaks occur which correspond to similar transitions for donors located near the center of a well.
Introduction (1999)

Abstract The book recounts the lives of Jews in Nazi Germany and delves into their day-to-day lives within their homes, amongst their families, and within their communities. The author traces the beginnings of Nazi oppression and examines the reasons why the Jews reacted in the manner that they did. Throughout the book, anecdotes and accounts gleaned from survivors and their personal correspondences are presented and analyzed. Part of the account deals with the daily lives of Jewish women and their history in Germany. The insights gleaned from this study reveal part of the reason why the Jews were perceived to be ambivalent or slow in realizing the dangers of Nazi oppression. The book balances the discussion with the inclusion of the experiences and consciousness of average Germans in the same period. The section ends with an overview of the Jewish community before 1933 and after the establishment of a racial state.
Technology and applications of micromachined silicon adaptive mirrors (1997)

The technology of low-cost high-quality micromachined adaptive mirrors is reported. Adaptive mirrors are fabricated by combining bulk silicon micromachining with standard electronics technologies. Mirrors with tens of control channels, having RMS initial deviation from plane of the order of ?/20 and a range of surface deflection of 10 to 20 ?m with linear frequency response in the range of 50 Hz to 1 kHz, are fabricated on standard PCB substrates. Advanced devices with hundreds of control channels, demanding integration of driver and switching electronics, are currently under development
Prostaglandin 15d-PGJ2 Inhibits Androgen Receptor Signaling in Prostate Cancer Cells (2012)

Androgen signaling, in particular overexpression of the androgen receptor (AR), is critical for the growth and progression of prostate cancer. Because the AR is amenable to targeting by small-molecule inhibitors, it remains the major druggable target for the advanced disease. Inflammation has also been implicated in the cancerous growth in the prostate. Here we show that 15-deoxy-Δ(12,14)-prostaglandin J(2) (15d-PGJ(2)), an endogenously produced antiinflammatory prostaglandin, targets the AR and acts as a potent AR inhibitor, rapidly repressing AR target genes, such as FKBP51 and TMPRSS2 in prostate cancer cells. However, exposure of prostate cancer cells to 15d-PGJ(2) does not simply evoke a general inhibition of nuclear receptor activity or transcription because under the same conditions, peroxisome proliferator-activated receptor-γ is activated by 15d-PGJ(2). Moreover, 15d-PGJ(2) rapidly triggers modifications of AR by small ubiquitin-related modifier-2/3 (SUMO-2/3), which may modulate the repressing effect of 15d-PGJ(2) on AR-dependent transcription. Chromatin immunoprecipitation assays indicate that the inhibitory effect of 15d-PGJ(2) on FKBP51 and TMPRSS2 expression occurs in parallel with the inhibition of the AR binding to the regulatory regions of these genes. However, the DNA-binding activity is not the only AR function targeted by 15d-PGJ(2) because the prostaglandin also blunted the androgen-dependent interaction between the AR amino and carboxy termini. In conclusion, our results identify 15d-PGJ(2) as a potent and direct inhibitor of androgen signaling, suggesting novel possibilities in restricting the AR activity in prostate cancer cells.
Fat and Fatty Acid Requirements and Recommendations for Infants of 0&ndash;2 Years and Children of 2&ndash;18 Years (2009)

Summary of current recommendations for LCP intakeInstitution LCP daily recommended intake for infants 1 FAO/WHO, 1994 20 mg/kg body weight2 Agence francaise de securite sanitaire des aliments, CNERNA-CNRS, 2001 –3 Health Council of the Netherlands, 2001 80 mg/kg body weight4 Commission of the European Communities, 2006 a n–6 LCP 2% of total fat max,1% as AA. DHA 6 0.2% of total fat5 WHO/FAO, 2003 TRS 916 –6 UK Scientific Advisory Committee on Nutrition, 2004 –7 International Society for the Study of Fatty Acids and Lipids, 2008 AA 0.5% of total fatDHA 0.35% of total fat8 Deutsche Gesellschaft fur Ernahrung, 2005 –9 Perinatal Lipid Intake Working Group, 2007 b DHA 6 0.2% of total fat10 Position of the American Dietetic Association and Dietitians of Canada, 2007 c –11 World Association of Perinatal Medicine, 2008 Infant formulae and baby foods:DHA: 0.2–0.5% of fatty acids EPA≤DHA, AA≥DHA a The Commission of the European Communities. Commission Directive 2006/141/EC of 22 December 2006 on infant formu-lae and amending Directive 1999/21/EC. Official Journal of the European Union 30.12.2006:L401/1401/33.
Deformable mirrors for all seasons and reasons (1982)

The use of adaptive optics has been increasingly proposed as a solution to a variety of optical phase distortion problems. Deformable (rubber) mirror concepts have utilized numerous design techniques for phase distortion correction. Deformable mirror requirements are reviewed for several applications along with projected requirements to meet the demands of future optical systems. Actuator and mirror design requirements are addressed along with their interrelationship with electronic driver design.
An Approach for Triangle Traffic Sign Detection Based on Improved Radon Transform (2012)

Aimed at the complexity of the traffic, this paper presents a triangle traffic sign detection method using Radon transform . the process of detection consists of three parts. Firstly, the background in image is filtered by the color characteristics of triangle traffic sign. Then the target image is transformed from two-dimensional space to Radon projection space. Finally, triangle traffic signs in image are extracted according to characteristics of triangle in Radon projection space. Experimental results show that the proposed method has a good effect on accuracy of detection and also can detect traffic sign area for triangle traffic signs of geometric distortion.
AIMING: Resource Allocation with Latency Awareness for Federated‐Cloud Applications (2018)

Federated‐cloud has been widely deployed due to the growing popularity of real‐time applications, and hence allocating resources among clouds becomes nontrivial to meet the stringent service requirements. The challenges lie in achieving minimized latency constrained by virtual machines rental overhead and resource requirement. This becomes further complicated by the issues of datacenter selection. To this end, we propose AIMING, a novel resource allocation approach which aims to minimize the latency constrained by monetary overhead in the context of federated‐cloud. Specifically, the network resources are deployed and selected according to k ‐means clustering. Meanwhile, the total latency among datacenters is optimized based on binary quadratic programming. The evaluation is conducted with real data traces. The results show that AIMING can reduce total datacenter latency effectively compared with other approaches.
Ta nanotubes grown by glancing angle deposition (2008)

Regular arrays of vertical 200-nm-diameter hollow Ta tubes were grown by glancing angle deposition (GLAD) onto Cr nanoring patterns that were fabricated by positive-resist e-beam lithography followed by nondirectional Cr deposition and a lift-off process. During GLAD, nanorods nucleate around the edges of the patterned rings, broaden, and merge to form tubes with 50-nm-thick walls. The nanotubes remain open during continued growth, with a slight (13%) decrease in the effective inner diameter for an increasing tube height from 200 to 600 nm. These results demonstrate that complex patterned two-dimensional shapes can be extended into the third dimension using the GLAD process.
474. The ionization of ethyleneimine and polyethyleneimine (1956)

E. J. Shepherd and J. A. Kitchener, J. Chem. Soc., 1956, 2448 DOI: 10.1039/JR9560002448
An automatic tracer of characteristic curves for optically pumped lasers (1967)

Apparatus for automatically recording photographically points on plots of laser output energy against excitation energy is described. A variable pause between shots is possible and the excitation pulse length and energy range can be varied to suit requirements. The detector described measures the fluorescence from a ruby used to integrate laser light: more conventional detectors can be used but may give an increased scatter of points or not hold their absolute calibration. Standard errors of 2% in threshold and slope are obtained with an absolute accuracy to 4%.
Intrathecal application of interferon gamma. Progressive appearance of MHC antigens within the rat nervous system. (1990)

Intrathecal injection of interferon-gamma induced a significant increase of the number of class I and class II major histocompatibility complex (MHC)-expressing cells within the rat nervous system. A progressive appearance of MHC-antigen-positive cells was found by light- and electron microscopic immune histology. The first level comprised cells that constitutively expressed MHC antigens in normal animals (meningeal and endoneural monocytes, some perivascular dendritic cells, and few parenchymal microglia cells, especially in the lumbar spinal cord and in the cerebellar white matter). The second level represented cells readily expressing MHC antigens after stimulation with interferon-gamma (all perivascular, dendritic cells, and microglia). The third level included ependymal cells, astrocytes, and Schwann cells. After stimulation with interferon-gamma, these neuroectodermal cells expressed MHC antigens inconsistently, usually in a low density and patchy distribution. The progressive appearance of MHC antigens may be reflected by the variances of lesional patterns found in experimental allergic encephalomyelitis of different histologic severity.
NON-IONIC—CATIONIC MICELLAR PROPERTIES OF DIMETHYLDODECYLAMINE OXIDE<sup>1</sup> (1962)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTNON-IONIC—CATIONIC MICELLAR PROPERTIES OF DIMETHYLDODECYLAMINE OXIDE1K. W. HerrmannCite this: J. Phys. Chem. 1962, 66, 2, 295–300Publication Date (Print):February 1, 1962Publication History Published online1 May 2002Published inissue 1 February 1962https://pubs.acs.org/doi/10.1021/j100808a025https://doi.org/10.1021/j100808a025research-articleACS PublicationsRequest reuse permissionsArticle Views562Altmetric-Citations151LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
From Time Sharing to Real Time-Sharing of a Really Good Time in the Last 40 Years. (1999)

Effects of flange size on the flow patterns of an exterior circular hood subject to the influence of various uniform cross drafts were studied in an apparatus consisting of hood-model/wind-tunnel assembly. The cross draft to suction velocity ratio covered the range from 0.056 to 0.792. The flange width to hood diameter ratio spanned from 1.2 to 3.0. The hood equipped without flange was also probed. A two-component laser Doppler anemometer was used to measure the velocity field on the symmetry plane. The streamline patterns were obtained from the measured velocity data. The cross draft caused a capture envelope. The boundary of the envelope was described by a dividing streamline. It was found that the flange width presented complex effects on the capture envelope and the dividing streamline. Corresponding to a cross draft to suction velocity ratio, a critical flange width existed. If the flange width was smaller than the critical value, the dividing streamline would terminate at the downstream tip of the flange. The behaviors of the capture envelope and the dividing streamline of the hood in cross draft under different flange widths are presented and discussed.
A Role for the Distal Carboxyl Tails in Generating the Novel Pharmacology and G Protein Activation Profile of μ and δ Opioid Receptor Hetero-oligomers (2005)

Opioid receptor pharmacology in vivo has predicted a greater number of receptor subtypes than explained by the profiles of the three cloned opioid receptors, and the functional dependence of the receptors on each other shown in gene-deleted animal models remains unexplained. One mechanism for such findings is the generation of novel signaling complexes by receptor hetero-oligomerization, which we previously showed results in significantly different pharmacology for mu and delta receptor hetero-oligomers compared with the individual receptors. In the present study, we show that deltorphin-II is a fully functional agonist of the mu-delta heteromer, which induced desensitization and inhibited adenylyl cyclase through a pertussis toxin-insensitive G protein. Activation of the mu-delta receptor heteromer resulted in preferential activation of Galpha(z), illustrated by incorporation of GTPgamma(35)S, whereas activation of the individually expressed mu and delta receptors preferentially activated Galpha(i). The unique pharmacology of the mu-delta heteromer was dependent on the reciprocal involvement of the distal carboxyl tails of both receptors, so that truncation of the distal mu receptor carboxyl tail modified the delta-selective ligand-binding pocket, and truncation of the delta receptor distal carboxyl tail modified the mu-selective binding pocket. The distal carboxyl tails of both receptors also had a significant role in receptor interaction, as evidenced by the reduced ability to co-immunoprecipitate when the carboxyl tails were truncated. The interaction between mu and delta receptors occurred constitutively when the receptors were co-expressed, but did not occur when receptor expression was temporally separated, indicating that the hetero-oligomers were generated by a co-translational mechanism.
Priority Transmission of SIP Signaling Flows in Case of IP Link Congestion (2009)

Conceptual framework of Next Generation Network (NGN) is based on Internet Protocol (IP) transport technology, which is generally accepted as the optimal solution for delivering of next generation multimedia services. Although packet-switched networks are in the mainstream, decades of experience with circuit-switched networks still set expectations when it comes to Quality of Service (QoS). As opposed to circuit-switched networks, signaling flow and media flow of NGN services are mixed in transmission. That makes it difficult for an IP network node to guarantee the signaling flow packet is not discarded in case of the congestion, which results in an impossibility to trigger the framework of dynamic QoS negotiation and implement service reachability. Since the service reachability is guaranteed in the signaling flow transmission aspect, it is necessary to consider the possibility of IP network to fulfill expectations regarding the straightway and reliable transmission of signaling flows. In this paper, the link congestion effect on critical performance metrics of Session Initiation Protocol (SIP) signaling flows is investigated by performing extensive simulation study. Our results indicate that IP network is able to guarantee transmission criteria of SIP signaling flows even in case of critical link congestion when the highest priority is assigned to them.
SHEFFIELD INTRA-MEDULLARY TELESCOPING NAIL SYSTEM FOR MANAGING RECURRENT FRACTURES AND DEFORMITY PROBLEMS IN THE LONG BONES OF THE LOWER LIMBS IN CHILDREN (2011)

We report the our experience of using the Sheffield intra-medullary telescoping nail system for managing recurrent fractures and deformity problems in the long bones of the lower limbs. 15 children with conditions like osteogenesis imperfecta, fibrous dysplasia and neurofibromatosis were operated from the years 1993 to 2001 and followed up for a mean period of five years nine months. The average age at the time of the initial nailing was six years. In all, 21 femurs and 10 tibiae were nailed. A total of thirteen complications were noted in seven patients, including re-fractures with the nail-in-situ in seven bones, migration of the rods in four bones, fracture of the nail and one sub-clinical infection after femur nailing. Nine revision operations were necessary to address these problems including removal of the infected nail. All these revisions were successful. The estimated 5 year cumulative survival rate was 73% for femur and 75% for tibia. We have not experienced any evidence of epiphyseal damage after the procedure. All our patients can ambulate independently now. Elongating intramedullary rods are ideal in children with any condition that can cause recurrent fractures or limb deformity as they improve walking capability and prevent further deformity.
Boron-Doped Carbon Nanotubes Serving as a Novel Chemical Sensor for Formaldehyde (2006)

To search for a novel sensor to detect the presence of formaldehyde (HCOH), we investigate reactivities of the intrinsic and boron-doped (B-doped) single-walled (8, 0) carbon nanotube (SWCNT) with HCOH using density functional theory calculations. Compared with the intrinsic SWCNT, the B-doped SWCNT presents high sensitivity to HCOH. This is attributed to the strongly chemical interaction between the electron-rich oxygen atom of HCOH and the electron-scarce boron atom of the doped SWCNT. B-doped SWCNTs are expected to be a potential candidate for detecting the presence of HCOH.
An investigation into the role and meaning of occupation for people living with on‐going health conditions (2012)

This study contributes a theoretical understanding of the roles and meaning of occupation that is grounded in the experiences of people living with on-going health conditions. These findings extend our understanding of human occupation, and highlight the importance of narrative techniques to support occupation-based practice and empower people living with on-going illness.
A multi-pulse LPC speech codec using digital signal processors (2005)

A full-duplex 16 or 9.6 k bits/sec speech codec based on the multi-pulse excited LPC coding technique has been developed. Cross-correlation analysis was used for the pulse search method. The codec was implemented by using five NEC 7720 Digital Signal Processor LSI chips ; four DSPs for the coder and one DSP for the decoder. A general purpose microprocessor was also used for system control. Reconstructed speech was quite natural and almost undiscernible from original speech at 16 k bits/sec and still quite good at 9.6 k bits/sec. Signal to noise power ratio for a sine wave signal was 30 dB at 16 k bits/sec.
58.1: A 4.1‐Inch Flexible QVGA AMOLED Using a Microcrystalline‐Si:H TFT on a Polyimide Substrate (2009)

Abstract A 4.1‐inch flexible QVGA AMOLED display with microcrystalline silicon (μc‐Si:H) TFTs backplane on colorless polyamide (PI) substrate is demonstrated. The PI substrate has the features of high T g (∼350°C) and high light transmittance (∼90%). The bottom‐gate μc‐Si:H TFTs backplane is fabricated at 200°C by a conventional (13.56 MHz) plasma‐enhanced chemical vapor deposition (PECVD) system. The flexible μc‐Si:H TFTs backplane shows better electrical stability, flexibility, and uniformity.