gebhart/patrepeval huggingface dataset:
Isolation and Characterization of Virus-resistant Mouse Embryo Fibroblasts (1973)

SUMMARY A method is described for the isolation of virus-resistant mutants of mammalian cells in culture. Cells of a mouse embryo fibroblast line (3T6) were treated with a mutagen and subjected to selection for virus resistance. The cells were infected with a temperature-sensitive mutant of Sindbis virus which was allowed to proceed through one cycle of replication at the permissive temperature. On transfer of the cells to the non-permissive temperature, further cycles of virus replication were prevented and non-infected cells allowed to grow out. Repetition of this procedure over 2 months resulted in the isolation of a population of 3T6 cells which resisted infection by Sindbis virus. Single cell clones were isolated that were resistant to the growth of Sindbis virus and also to the growth of Mengo virus, Semliki Forest virus, vesicular stomatitis virus, Newcastle Disease virus, vaccinia virus and herpes simplex virus.
The Separation of AHF from Fibrinogen. III (1961)

Summary A chromatographic method is outlined permitting to obtain quantitatively the AHF, contained in 250 ml of human plasma, in a fibrinogen-free state.
Multiview Convolutional Neural Networks for Multidocument Extractive Summarization (2016)

Multidocument summarization has gained popularity in many real world applications because vital information can be extracted within a short time. Extractive summarization aims to generate a summary of a document or a set of documents by ranking sentences and the ranking results rely heavily on the quality of sentence features. However, almost all previous algorithms require hand-crafted features for sentence representation. In this paper, we leverage on word embedding to represent sentences so as to avoid the intensive labor in feature engineering. An enhanced convolutional neural networks (CNNs) termed multiview CNNs is successfully developed to obtain the features of sentences and rank sentences jointly. Multiview learning is incorporated into the model to greatly enhance the learning capability of original CNN. We evaluate the generic summarization performance of our proposed method on five Document Understanding Conference datasets. The proposed system outperforms the state-of-the-art approaches and the improvement is statistically significant shown by paired t -test.
Toward the Design of Robust Information Systems (1989)

:Current design approaches are not focused on yielding computer-based information systems which are robust to rapidly changing environments. The 1990s are bringing with them an increasing inter-organizational locus of information systems, a tighter coupling of information systems to strategic management, and an increasing turbulence of operational environments. In combination, these factors are making robustness under dynamic conditions a key effectiveness requirement of many large computer-based information systems. Coming from a strategic planning perspective, this paper explores the challenge of designing robust information systems and suggests some prescriptive guidelines for improving the process.
A Study on Formant Variation with Drinking and Nondrinking Condition (2009)

본 논문은 음주와 비음주 상태를 판별하기 위한 포어먼트 변화의 특징에 관한 연구이다. 단음절의 실험을 통하여 음주 음성신호에 비하여 비음주 음성신호의 F1, F2, F3의 포어먼트가 높게 나타나는 것을 확인하였으며, 또한 포어먼트는 음주와 비음주 상태를 구별하는데 매우 유효하다는 것을 알 수 있었다. This paper present a characteristic of formant variation in order to discriminate between drinking and nondrinking condition. By simulation experiments based on monosyllable, it is shown that the higher formant in F1, F2 and F3 in drinking speech signals compared with nondrinking speech signals. And I knew that the formant is very effective at distinction of drinking condition and nondrinking condition.
Porous hydroxyapatite and gelatin/hydroxyapatite microspheres obtained by calcium phosphate cement emulsion (2011)

Hydroxyapatite and hybrid gelatine/hydroxyapatite microspheres were obtained through a water in oil emulsion of a calcium phosphate cement (CPC). The setting reaction of the CPC, in this case the hydrolysis of α-tricalcium phosphate, was responsible for the consolidation of the microspheres. After the setting reaction, the microspheres consisted of an entangled network of hydroxyapatite crystals, with a high porosity and pore sizes ranging between 0.5 and 5 μm. The size of the microspheres was tailored by controlling the viscosity of the hydrophobic phase, the rotation speed, and the initial powder size of the CPC. The incorporation of gelatin increased the sphericity of the microspheres, as well as their size and size dispersion. To assess the feasibility of using the microspheres as cell microcarriers, Saos-2 cells were cultured on the microspheres. Fluorescent staining, SEM studies, and LDH quantification showed that the microspheres were able to sustain cell growth. Cell adhesion and proliferation was significantly improved in the hybrid gelatin/hydroxyapatite microspheres as compared to the hydroxyapatite ones.
Some Algorithms for Linear Spline and Piecewise Multiple Linear Regression (1976)

Abstract This paper develops some efficient algorithms for linear spline and piecewise multiple linear regression. A plotting procedure that shows the existence and location of changes in linear regression models is developed as an adjunct to one of the algorithms. The algorithms are compared with other presently available algorithms both in terms of efficiency and in terms of performance on sets of artificial data. An example shows how the algorithms, implemented in portable FORTRAN IV, can be used profitably in the analysis of data.
Fly-by-wire flight control (1999)

Fly-by-wire flight control has enabled a watershed improvement in aircraft performance and control to be achieved. This article covers first the basic concepts of FBW control and key elements such as electrical data transmission, failure survival actuation systems, aircraft motion sensors, and air data systems. Aircraft stability is then briefly described. The unique advantages of FBW control are next covered and roll rate and pitch rate manoeuvre command control explained. Safety and integrity requirements are then discussed together with failure survival redundancy. The architecture and implementation of a quadruplex FBW system is explained. The problem of common-mode failures and the need for dissimilar redundancy are covered and the methods used to achieve dissimilar redundancy described.
STRUCTURE AND EVOLUTION OF THE<i>rp1 COMPLEX</i>CONFERRING RUST RESISTANCE IN MAIZE (1997)

Genetic analyses of the rp1 rust resistance complex of maize have demonstrated that recombination plays a central role in the creation of genetic diversity at the locus. The generation of rp1 diversity is promoted by a high rate of intragenic recombination coupled with a tendency for genes in the complex to mispair in meiosis. Among the novel rp1 genes that have been identified include genes with novel race-specificities and genes conferring lesion mimic phenotypes. Recombinants have also been identified that confer partial resistance which is apparently non-race-specific and may be useful in controlling maize rusts in a durable manner.
IFES 2013: Farms and the Affordable Care Act (2014)

Effective January 1, 2013, there are two new Medicare taxes that will affect higher-income farmers. The Net Investment Income Tax (NIIT) is a new 3.8% tax on certain types of passive income. Wages, self-employment income and other sources of income subject to Medicare tax may be subject to the new Additional Medicare tax of 0.9%. Whether these taxes will affect a farmer depends upon the farmer's tax filing status and level of adjusted gross income (AGI) for the year. The income thresholds for each filing status are as follows.
White-pine weevil control with knapsack mistblower (1962)

Tests made in New York State in 1956-60 indicate that the portable knapsack mistblower has considerable promise for practical control of the white-pine weevil, now the major insect enemy of white pine in the Northeast. Lindane and malathion, alone and with Aroclor 5460, were the toxicants used in the tests.
Compensation of Power Amplifier Long-Term Memory Behavior for Pulsed Radar Applications (2019)

Pulsed radar amplifiers are known to present severe long-term memory effects in their pulse-to-pulse stability. These are usually attributed to electrothermal dynamics or to trapping effects originated in gallium-nitride (GaN) HEMTs. Expanding on our previous work where we devised a method for determining a suitable dynamic variation in the HEMT's gate-source voltage for compensating these long-term memory effects in single-ended amplifiers, in this article, we present a feed-forward model to calculate this compensation signal in real-time pulsed radar applications.
Ribonuclease “XlaI,” an Activity from <i>Xenopus laevis</i> Oocytes that Excises Intervening Sequences from Yeast Transfer Ribonucleic Acid Precursors (1981)

A ribonuclease (RNase) activity, RNase "XlaI," responsible for the excision of intervening sequences from two yeast transfer ribonucleic acid (tRNA) precursors, pre-tRNA(Tyr) and pre-tRNA(3Leu), has been purified 54-fold from nuclear extracts of Xenopus laevis oocytes. The RNase preparation is essentially free of contaminating RNase. A quantitative assay for RNase XlaI was developed, and the reaction products were characterized. RNase XlaI cleavage sites in the yeast tRNA precursors were identical to those made by yeast extracts (including 3'-phosphate and 5'-hydroxyl termini). Cleavage of pre-tRNA(3Leu) by RNase XlaI and subsequent ligation of the half-tRNA molecules do not require removal of the 5' leader or 3' trailer sequences.
Lactoferrin is a survival factor for neutrophils in rheumatoid synovial fluid (2008)

Lactoferrin contributes to extended neutrophil survival in the rheumatoid joint in the established phase of RA but not in very early arthritis.
Channel estimation from known preamble sequences (2003)

The least sum of squared estimation (LSSE)channel estimation algorithm is applied for determining a channel impulse response from known preamble sequences. Optimum training sequences are designed for different channel responses and training sequence lengths. The effect of channel estimation errors on the performance of some data detectors is also investigated. As a special case some non-maximal length sequences and ternary sequences (with alphabet 0, /spl plusmn/1) are also considered for performance evaluation.
William T. McClatchey (2000)

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Measurements on X-Ray Production and Absorption in the Range 0.7 to 2.5 Mv (1943)

In the voltage range from 0.7 to 2.5 Mv, the intensity and the total mass absorption coefficient of the heterogeneous radiation produced in a thick gold target have been measured as a function of tube voltage, angle with respect to the electron beam, and thickness and material of the filter. Curves giving the dependence of absorption coefficient on voltage are presented for lead, tin, copper, aluminum, carbon, and water as absorbers. A method is described for calculating the absorption coefficient of the heterogeneous radiation produced at a given tube voltage and subjected to a given amount of filtration, utilizing accepted values for the absorption coefficient of homogeneous radiation. Measured and calculated values of the absorption coefficients for heterogeneous radiation are in good agreement. Curves giving the dependence of intensity on angle are in qualitative agreement with approximate theory. Curves giving the dependence of absorption coefficient on angle and the dependence of intensity in the forward direction on voltage are presented. A method for calculating the efficiency of x-ray production from these data is described and used to obtain results in satisfactory agreement with theory in the voltage range from 0.90 to 2.35 Mv.
Blind deconvolution of signals using a complex recurrent network (2002)

An algorithm for the separation of mixtures of signals was derived by Jutten and Herault (1991) under the assumption that the signals are independent. This algorithm is based on higher order moments and has also been applied to deconvolving signal mixtures. In practical problems where the order of the convolving filter may be high, frequency domain approaches are known to provide a more computationally efficient method of deconvolution. In this paper, the authors introduce a complex recurrent network structure for performing blind deconvolution. The aim is to investigate the performance of this approach for separating unknown, convolved signals which may occur in a situation such as the well-known 'cocktail-party problem'.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Further urinary metabolites of delta 1-tetrahydrocannabinol in man. (1982)

The in vivo metabolism of delta 1-tetrahydrocannabinol (delta 1-THC) was further investigated in man after oral administration. Five dicarboxylic acids were isolated from the urine and identified by gas chromatography-mass spectrometry. None of these acids have been identified in man before and two of them (3",4",5"-trisnor-delta 1-THC-7,2"-dioic acid (15) and 5"-nor-delta 1-THC-7,4"-dioic acid (17)) have hitherto not been found in any species. The major dicarboxylic acid was 4",5"-bisnor-delta 1-THC-7,3"-dioic acid (16) corresponding to 8% of the excreted radioactivity in the urine. The other dicarboxylic acids (14, 18) were present in small amounts.
The identification and estimation of elastase in serum and plasma (1966)

1. Electrophoretic separation of partially purified elastase preparations from pancreas followed by incubation of the electrophoretogram in contact with an agar gel containing 4% of either Congo Red-stained or unstained elastin demonstrated that the enzyme which dissolves elastin can be identified with that which releases dye from the stained preparation. 2. A method for the estimation of elastase based on the release of dye from Congo Red-stained elastin is described. It is 23 times as sensitive as methods employing protein determination. 3. With the method, elastase activity can be identified in plasma and in a partially fractionated plasma protein preparation. 4. Lineweaver-Burk plots of these estimates of activity at a variety of substrate concentrations indicate that the reaction between elastase and the dyed elastin is more closely similar to that between elastase and the soluble substrate elastin rather than to that between elastase and the solid substrate. 5. Values for K(m) and V(max.) calculated for the enzyme present in plasma present further evidence for its identity with the pancreatic enzyme. 6. By calculation of the slopes of the Lineweaver-Burk plots for various enzyme concentrations it has proved possible to demonstrate that the inhibitor which is also present in the plasma is without effect on the enzyme when it acts on the dyed substrate.
Synthesis of Natural Cytotoxic Camphorataimides B and C (2006)

Recently isolated camphorataanhydride A and cytotoxic camphorataimides B and C have been synthesized using chemo­selective SN2′ Grignard coupling reaction of p-methoxyphenyl­magnesium bromide with dimethyl bromomethylfumarate and chemoselective allylic substitution of bromide in bromoanhydride 9 with 2-propylmagnesium bromide as the key reactions. The present approach is general in nature and can be easily used to design the congeners of camphorataanhydrides/imides for structure-activity relationship studies.
Antifatigue Activity of Tissue Culture Extracts of<i>Saussurea involucrata</i>. (2008)

The antifatigue effect of the tissue culture of Saussurea involucrata. (TCSauI) KAR. et. KIR. (Compositae) was investigated in mice on swimming time, hepatic glycogen content, serum lactic acid content, serum urea-nitrogen, and serum lactate dehydrogenase. The current study provides evidence that TCSauI has antifatigue activity, suggesting the potential of the tissue culture technique to substitute for wild S. involucrata. (WSauI) in the pharmaceutical industry.
Physiology of Sporeforming Bacteria Associated with Insects: Minimal Nutritional Requirements for Growth, Sporulation, and Parasporal Crystal Formation of <i>Bacillus thuringiensis</i> (1974)

A defined medium is described in which 18 strains of Bacillus thuringiensis representing the 12 established serotypes grow, sporulate, and produce a parasporal crystal. This minimal medium contains glucose and salts supplemented with either aspartate, glutamate, or citrate. These organic acids are required and cannot be replaced by vitamin mixtures or succinate even though succinate is taken up at a rate similar to that of aspartate, glutamate, and citrate.
Activation of mitogenic signaling by endothelin 1 in ovarian carcinoma cells. (1997)

Endothelin 1 (ET-1) is produced in ovarian cancer cell lines and has been shown to act through ET(A) receptors as an autocrine growth factor to promote tumor cell proliferation in vitro. In OVCA 433 cells, the efficacy of ET-1 as a stimulus of [3H]thymidine incorporation was equivalent to that of epidermal growth factor. ET-1 also stimulated the rapid expression of c-fos, an action mediated by ET(A) receptors. The mitogenic action of ET-1 was not mediated by a pertussis toxin-sensitive G protein. An analysis of the effects of inhibition and depletion of protein kinase C (PKC) on mitogenic responses demonstrated that PKC was necessary but not sufficient for maximal stimulation by ET-1. In quiescent OVCA 433 cells, ET-1-induced stimulation of [3H]thymidine incorporation was prevented by two structurally distinct inhibitors of tyrosine kinase, herbimycin A and genistein. These results indicate that both PKC and protein tyrosine kinase participate in ET-1-stimulated mitogenic signaling. ET-1 rapidly stimulated tyrosine phosphorylation of several cellular proteins, among which p125FAK and p42 mitogen-activated protein kinase were identified. The additivity between the potent mitogenic actions of ET-1 and epidermal growth factor is consistent with the independence of their signal transduction pathways in ovarian cancer cells. These findings also indicate that intracellular signaling between the ET(A) receptor and a yet unidentified tyrosine kinase is involved in the mitogenic response to ET-1.
<b>Gibberellin‐photoaffinity labelling of two polypeptides in plant plasma membranes</b> (1998)

Two polypeptides of M(r) 68 kDa and 18 kDa were gibberellin (GA)-photoaffinity labelled in vitro in plasma membrane preparations from oat (Avena sativa L.) aleurone and from leaves and stems of wild-type and GA-sensitivity mutants of different species. Labelling of these polypeptides could be competed by biologically active, but not by inactive, GAs, indicating the likely biological significance of these interactions. On 2-dimensional gels the radiolabelled polypeptides were each resolved as one intensely labelled low abundance spot with a slightly lower pl form adjacent to it. There was a strong pH dependency for both labelling events, which correlated well with pH values at which GA are known to be most biologically active. A semi-dwarf GA-sensitivity mutant of sweet pea (Lathyrus odoratus L.), lb, showed reduced photoaffinity labelling of both polypeptides compared with the wild type, Lb. In the GA-insensitive Arabidopsis thaliana mutant gai, the level of labelling was the same as in wild type, GAI. This is the first report of GA-binding proteins in plant plasma membranes. Some preliminary sequence data are given for one of the labelled polypeptides. We discuss these mutants and consider their possible roles in GA perception or action.
Noninvasive diagnosis of acute rejection of solid organ transplants (2004)

Accurate diagnosis of acute rejection remains a formidable challenge in organ transplantation. The current gold standard diagnostic test for acute rejection is histological examination of the transplanted organ. However, biopsy procedures are invasive and complications occur. Furthermore, sampling errors may bias the histological diagnosis. Not uncommonly, empiric anti-rejection therapy has to be provided prior to the availability of a confirmatory histological report. Thus, there is an urgent need for specific and sensitive noninvasive biomarkers of acute rejection. Herein, we review noninvasive strategies for the diagnosis of acute rejection of solid organ transplants.
Optimal and dynamic planning for Markov decision processes with co-safe LTL specifications (2014)

We present a method to specify tasks and synthesise cost-optimal policies for Markov decision processes using co-safe linear temporal logic. Our approach incorporates a dynamic task handling procedure which allows for the addition of new tasks during execution and provides the ability to re-plan an optimal policy on-the-fly. This new policy minimises the cost to satisfy the conjunction of the current tasks and the new one, taking into account how much of the current tasks has already been executed. We illustrate our approach by applying it to motion planning for a mobile service robot.
An Adulterine Castle on Faringdon Clump, Berkshire (1936)

From the market-place at Faringdon the Oxford road mounts steadily, passing under the north slope of the hill known variously as Faringdon Clump or Faringdon Folly. The hill is a rounded knoll, the summit of which stands 505 ft. O.D. and, besides being a well-known landmark in the Vale of White Horse, commands an extensive prospect in every direction. Like Cumnor Hurst, Shotover, Brill and others, it is one of a series of undenuded caps of Cretaceous sands overlying Berkshire oolites that crop out at intervals between Faringdon and Aylesbury. The sands are ferruginous, dark yellow with lighter sands below, divided by a layer of sandstone rock. On the summit of the hill is a clump of beeches and Scotch firs, probably planted here, as on so many similar eminences, in the late eighteenth or early nineteenth century.
A Radio Project Teaches Your Class (1985)

(1952). A Radio Project Teaches Your Class. Journal of the American Association for Health, Physical Education, and Recreation: Vol. 23, No. 9, pp. 14-31.
Design and development of a mobile crawling robot with novel halbach array based magnetic wheels (2017)

Higher efficiency and the safety of hull inspection can be achieved by replacing the conventional methods with modern crawling robots. This paper consists of detailed study of the design and development of a crawling robot with a novel permanent magnetic wheel based on Halbach magnetic array. The magnetic array and the wheel assembly were designed based on the magnetic simulation results. Maintaining the adequate adhesion force as well as the friction force of the wheels were considered in designing the wheels. The crawling robot is equipped with a steering system based on Ackermann steering method hence the steering angles are controlled by an algorithm and actuated using servo motors. The driving system of the robot is equipped with four geared stepper motors and they are controlled separately by the algorithm according to the inputs of the controller. The control architecture and the components used for the robot control system are explained. The operator can remotely control the robot and inspect the hull surface via the camera feed available in the HMI (Human Machine Interface) of the robot. The prototype of the crawling robot was tested in a similar environment and the test results are included in the paper.