gebhart/patrepeval huggingface dataset:
p-[(2-Amino-4-hydroxy-6-pteridylmethyl)-p' -nitrobenzenesulfonylamino]-benzoic Acid and Intermediates (1954)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTp-[(2-Amino-4-hydroxy-6-pteridylmethyl)-p' -nitrobenzenesulfonylamino]-benzoic Acid and IntermediatesBarney J. Magerlein and David I. WeisblatCite this: J. Am. Chem. Soc. 1954, 76, 6, 1702–1703Publication Date (Print):March 1, 1954Publication History Published online1 May 2002Published inissue 1 March 1954https://pubs.acs.org/doi/10.1021/ja01635a077https://doi.org/10.1021/ja01635a077research-articleACS PublicationsRequest reuse permissionsArticle Views47Altmetric-Citations1LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Funktions-und gewichtsoptimierte Zahnräder : additiv durch selektives Laserschmelzen hergestellt (2019)

Antriebssysteme müssen immer leichter und effizienter gestaltet werden. Kleinere Massenträgheitsmomente und optimierte Gestaltung für Kühlung, Schmierung und Zahneingriff können die Effizienz von Getriebe merklich erhöhen. Im SLM-Verfahren hergestellte Zahnräder mit typischen Getriebestählen wie beispielsweise dem 30CrNiMo8 bieten dabei grosses Potenzial. Der Vortrag zeigt, wie das Wissen im Bereich Zahnraddesign und des SLM-Verfahrens erfolgreich kombiniert werden.
AUTONOMOUS ADJUSTING OF MACHINE TOOLS IN FMS, IMPLEMENTATION AND RESULTS (2003)

Abstract – The aim of the project (AutoComp II) was to examine the possibilities to build an autonomous measuring and compensation system for a flexible manufacturing system, FMS. This goal has been introduced in detail at the Imeko 2000 conference in the paper &quot;Autonomous adjusting of machine tools in FMS&quot;. The focus of this paper is on the implementation and the results of the project.
Characterization of a cytosolic aminopeptidase from <i>Encephalitozoon intestinalis</i> (2002)

Aminopeptidase activity was detected in Encephalitozoon intestinalis using a fluorometric assay. The aminopeptidase was capable of hydrolysing different amino acids bound to 7-amino-4-trifluoromethyl coumarin, with maximal activity against the amino acid, leucine. Aminopeptidase activity was localized in E. intestinalis spores and in intracellular stages. Enzymatic activity was inhibited by the traditional aminopeptidase inhibitors, bestatin and its analogue, nitrobestatin. Inhibition with the chelating agents, EDTA and 1,10-phenanthroline, suggested that the enzyme activity belongs to the metalloaminopeptidase class. Subcellular fractionation demonstrated that maximal enzyme activity was localized in the cytosolic fraction. Direct fluorogenic substrate analysis by native polyacrylamide gel electrophoresis estimated a molecular weight of 70.8 kDa. Direct fluorogenic analysis by polyacrylamide ampholyte gel electrophoresis indicated an isoelectric point of 4.8. The enzyme was both heat (> 37 degrees C) and cold (< 0 degrees C) labile with an optimal activity at pH 7.2. This is the first report characterizing a cytosolic aminopeptidase in microsporidia.
Influence of Supramolecular Order on the Light-Induced Reorientation Process in Photochromic Side Group Polymers (1995)

Abstract A new approach for optical data storage is presented using amorphous films of photochromic polymers. Concerning the tendency to form supramolecular order these polymers are situated at the border between amorphous and Liquid Crystalline Polymers (LCP's). The light-induced reorientation of the photochromic azobenzene moieties by an angular-dependent photoselection process may cause a reorientation of the non-photochromic moieties. In this way an optical axis is generated in the initially amorphous films by a photochemically induced physical orientation process. The resulting values of optical anisotropy are close to those of aligned LCP films.
Multifrequency ESR of copper(II)-(His)n (His = histidine). 1. Immobile phase (1986)

ESR studies of Cu(histidine), in the presence of excess histidine at two microwave frequencies were undertaken to support either\nthe glycine-like or histamine-like complexes. Low-frequency, S-band data are well-resolved for the M, = -I/* line in the gH region,\nand the number of lines is attributed to four approximately equivalent nitrogen donor atoms. When the pH is increased from\n6.8 to 7.3, a second form is detected from the MI= line in the g,,re gion but not in other portions of the spectrum. The change\nin ESR parameters does not appear to be large enough to account for a change from four nitrogen donor atoms to three nitrogen\ndonor atoms in the square-planar configuration. This small change is more consistent with a change in axial coordination or a\nchange from four nitrogen donor atoms to an altered sef of four nitrogen donor atoms. Further ESR analysis of frozen copper-\nhistidine complexes in the presence of excess histidine where the I4N isotope in the imidazole ring is substituted with l5N is\nconsistent with a structure for which four equivalent ISN nitrogen donor atoms are bound to cupric ion.
Scale and Rotaion Invariant Pattern Detection Using Phase Information (2004)

In recent years, it has become important to develop a pattern detection method in the industrial field. Many methods have been proposed for the pattern detection. However, most of these methods have required high computational costs or vast memories to be implemented in small equipments. In this paper, we propose a new scale and rotation invariant pattern detection method using the phase information. This method mainly requires multiplications and additions, and the computational cost of the proposed method is low. Finally, we show the effectiveness of the method by simulations.
Modification of Activated Carbon Fiber by Metal Dispersion and Surface Functionalization for the Removal of 2-Chloroethanol (2011)

Nickel-impregnated phenolic resin precursor-based activated carbon fiber (ACF) was functionalized with pyridine and investigated for the adsorptive removal of 2-chloroethanol. Adsorption tests were carried out under flow conditions for different gas flow rates, solute concentrations, and temperatures in a perforated tubular adsorber. Various analytical and spectroscopic techniques, including X-ray diffraction (XRD), Fourier transform infrared (FT-IR) spectroscopy, scanning electron microscopy (SEM), and CHNSO elemental analysis, were used to characterize the adsorbents that have been prepared in this study. The results showed that the ACFs adsorbed significant amounts of 2-chloroethanol. Temperature had adverse effects on adsorption. At metallic concentrations in excess of 0.4 M of nickel, the formation of metal crystallites occurred, causing blockage of the pores and a decrease in the number of active metal sites. The functionalization of ACFs by pyridine was shown to produce a basic surface, resulting in the enhanced adsorption of the organic solute. The results have applications in the preparation of effective ACF-based adsorbents for controlling the emission of hazardous organic compounds.
Evaluation of the therapeutic use of radioactive monoclonal antibodies C242 and C215 in transplanted murine tumours. (1989)

The therapeutic roles of monoclonal antibodies C242 and C215 labelled with 131I were investigated in transplanted mammary carcinomas. Fragments (10 mg) of mammary tumour from (A x Pc) F1 hybrid mice were implanted subcutaneously in 72 mice of the same strain. Twelve mice were injected with 131I-C242 starting from day 12 following tumour implantation, and eight out of 12 survived for 60 days. By contrast all but one of 36 control mice died within the same time period (P less than 0.0001). Twelve mice were injected with 131I-C215. Seven out of the 12 were alive at 60 days whilst all but 1 of 36 control animals had died (P less than 0.0001). In this study targeted immunotherapy using 131I-labelled antibodies C242 and C215 inhibited tumour growth and prolonged survival. Measurements of tumour area showed a 27-39 percent reduction in the mice receiving the radiolabelled conjugates C242 and C215 (P less than 0.004 and P = 0.028 respectively).
Spatial and temporal variability of hyperspectral signatures of terrain (2008)

Electromagnetic signatures of terrain exhibit significant spatial heterogeneity on a range of scales as well as considerable temporal variability. A statistical characterization of the spatial heterogeneity and spatial scaling algorithms of terrain electromagnetic signatures are required to extrapolate measurements to larger scales. Basic terrain elements including bare soil, grass, deciduous, and coniferous trees were studied in a quasi-laboratory setting using instrumented test sites in Hanover, NH and Yuma, AZ. Observations were made using a visible and near infrared spectroradiometer (350 - 2500 nm) and hyperspectral camera (400 - 1100 nm). Results are reported illustrating: i) several difference scenes; ii) a terrain scene time series sampled over an annual cycle; and iii) the detection of artifacts in scenes. A principal component analysis indicated that the first three principal components typically explained between 90 and 99% of the variance of the 30 to 40-channel hyperspectral images. Higher order principal components of hyperspectral images are useful for detecting artifacts in scenes.
Geochemical and Microbiological Methods for Evaluating Anaerobic Processes in an Aquifer Contaminated by Landfill Leachate (2000)

A combined geochemical and microbiological approach was needed to delineate the biogeochemical processes occurring in an aquifer contaminated by landfill leachate in Norman, OK, where the important microbially mediated reactions in an anoxic plume were iron reduction, sulfate reduction, and methanogenesis. The highest rates of sulfate reduction (13.2 μM/day) were detected near the water table where sulfate levels were maximal (up to 4.6 mM). The enrichment of 34S in the sulfate pools (δ34S of SO42- was 67−69‰), and dissolved hydrogen measurements provided additional support for the importance of sulfate reduction near the water table. Methane was detected in the center of the plume where sulfate was depleted. Microbial incubations demonstrated concomitant sulfate reduction and methanogenesis in the anoxic portion of the plume. Although high concentrations of soluble reduced iron were detected throughout the aquifer and H2 levels were indicative of iron reduction under steady-state conditions, microbiological experiments showed that iron reduction was active only at the edges of the sulfate-depleted portion of the plume. This study demonstrates the benefits of using a combined geochemical and microbiological approach to elucidate the spatial distribution of biogeochemical processes in contaminated aquifers.
Sir Derek Harold Richard Barton. 8 September 1918 – 16 March 1998 (2002)

Derek Harold Richard Barton was born on 8 September 1918 in the Thames-side town of Gravesend in Kent, the only child of William Thomas Barton and Maude Henrietta ( née Lukes). His humble background gave no indication of the magnitude, depth and impact that his career would have on the lives of so many and the scientific community in general.
Sex-Determining Gene(s) on Distal 9p: Clinical and Molecular Studies in Six Cases* (2000)

We report on clinical and molecular findings in five karyotypic males (cases 1-5) and one karyotypic female (case 6) with distal 9p monosomy. Cases 1-3 and 6 had female external genitalia, case 4 showed ambiguous external genitalia, and case 5 exhibited male external genitalia with left cryptorchidism and right intrascrotal testis. Gonadal explorations at gonadectomy in cases 3 and 4 revealed that case 3 had left streak gonad and right agonadism, and case 4 had bilateral hypoplastic testes. Endocrine studies in cases 1-4 and 6 showed that cases 1, 3, and 6 had definite primary hypogonadism, with basal FSH levels of 54, 39, and 41 IU/L, respectively, whereas case 2 with severe malnutrition was unremarkable for the baseline values, and case 4 had fairly good testicular function. Fluorescence in situ hybridization and microsatellite analyses demonstrated that all cases had hemizygosity of the 9p sex-determining region distal to D9S1779, with loss of the candidate sex-determining genes DMRT1 and DMRT2 from the abnormal chromosome 9. Sequence analysis in cases 1-4 and 6 showed that they had normal sequences of each exon of DMRT1 and the DM domain of DMRT2 on the normal chromosome 9, and that cases 1-4 had normal SRY sequence. The results provide further support for the presence of a sex-determining gene(s) on distal 9p and favor the possibility of DMRT1 and/or DMRT2 being the sex-determining gene(s). Furthermore, as hemizygosity of the 9p sex-determining region was associated with a wide spectrum of gonadogenesis from agonadism to testis formation in karyotypic males and with primary hypogonadism regardless of karyotypic sex, it is inferred that haploinsufficiency of the 9p sex-determining gene(s) primarily hinders the formation of indifferent gonad, leading to various degrees of defective testis formation in karyotypic males and impaired ovary formation in karyotypic females.
La Langue Braj (Dialecte de Mathura). By Dhirendra Varma. 10 × 6, pp. vi + 135, map 1. Paris: Adrien–Maisonneuve, 1935. Frs. 35. (1938)

An abstract is not available for this content so a preview has been provided. Please use the Get access link above for information on how to access this content.
The Plant Origins of Herbal Medicines and Their Quality Evaluation (2002)

Abstract For Abstract see ChemInform Abstract in Full Text.
Immune recognition of tumor cells <i>in vivo</i>. I. Role of H‐2 gene products in T lymphocyte activation against minor histocompatibility antigens displayed by adenocarcinoma cells (1982)

Challenges from ADK-1t adenocarcinoma cells of BALB/c (H-2d, Mlsb) mouse origin are rejected by DBA/2 (H-2d, Mlsa) mice on the basis of differences in a limited number of minor histocompatibility antigens. This T lymphocyte-dependent reaction is highly specific, and efficiently triggered only by Ia+ leukocytes infiltrating the tumor mass. ADK-1t challenges depleted of Ia+ infiltrating BALB/c leukocytes grow and kill DBA/2 mice, whereas the simultaneous injection of Ia+-inactivated BALB/c leukocytes induces tumor rejection. The expression of Mlsb-incompatible determinants on the Ia+ BALB/c leukocyte membrane is irrelevant in the induction of this efficient T lymphocyte reaction against BALB/c minor histocompatibility antigens. By contrast, a critical requirement is H-2 matching between the Ia+ leukocytes and the recipient mice at the inductive phase of the reaction.
10. A Simple Pendulum Technique for Achieving Seismic Isolation (1990)

An innovative seismic isolation system, the Friction Pendulum System (FPS), offers improvements in strength, versatility and ease of installation as compared to previous systems. Moreover, the approach offers several inherent performance benefits not available before. The FPS uses geometry and gravity to achieve the desired seismic isolation results. It is based on well known engineering principles of pendulum motion, and is constructed of materials with demonstrated longevity and resistance to environmental deterioration. The desirable isolation characteristics exhibited by FPS components hold the promise of an effective and practical system for significantly increasing the seismic resistance of new and existing buildings. This paper summarizes results of a comprehensive research and testing program to assess the technical performance of the FPS. In addition, an example building design using the FPS is given.
Formulation, characterization and optimization of liposomes containing eicosapentaenoic and docosahexaenoic acids; a methodology approach. (2014)

Omega-3 fatty acids (FAs) have been shown to prevent cardiovascular disease. The most commonly used omega-3 fatty acids like eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) are highly vulnerable to oxidation and therefore, have short shelf life. Recent advances in nanoliposomes provided a biocompatible system for stabilizing omega-3 FAs. Several methods could be implemented to prepare nanoliposomes. To the best of our knowledge, the performances of these methods in preparation omega-3 FAs have not been examined. Nanoliposomes were prepared by thin film hydration followed by one of the following methods: 1- extrusion, ultrasonic irradiation; 2- bath sonication; 3- probe sonication; or 4- combined probe and bath sonication. The size of liposomes obtained from methods 1 to 4 were 99.7 ± 3.5, 381.2 ± 7.8, 90.1 ± 2.3, and 87.1 ± 4.10 nm with zeta potential being -42.4 ± 1.7, -36.3 ± 1.6, -43.8 ± 2.4, and 31.6 ± 1.9 mV, respectively. The encapsulation efficiency (EE) for DHA was 13.2 ± 1.1%, 26.7 ± 1.9%, 56.9 ± 5.2% and 51.8 ± 3.8% for methods 1 to 4, respectively. The corresponding levels for EPA were 6.5 ± 1.3%, 18.1 ± 2.3%, 38.6 ± 1.8%, and 38 ± 3.7%, respectively. The EE for DHA and EPA of liposomes for both methods 3 and 4 increased significantly (p<0.05). Propanal, as the major volatile product formed during liposomal preparations, amounts from 81.2 ± 4.1 to 118.8 ± 2.3 μg/Kg. The differential scanning calorimetry (DSC) study showed that DHA and EPA influence the phase transition temperature of small unilamellar vesicles (SUVs) of dipalmitoyl phosphatidyl choline (DPPC). Transmission electron microscopy (TEM) images of liposomes stained with uranyl acetate showed that the liposomes were spherical in shape and maintain high structural integrity. In conclusion, probe ultrasound of pre-formed liposomes facilitates significant loading of DHA and EPA into the nanoliposomal membrane.
Privacy in geo-social networks: proximity notification with untrusted service providers and curious buddies (2010)

A major feature of the emerging geo-social networks is the ability to notify a user when one of his friends (also called buddies) happens to be geographically in proximity with the user. This proximity service is usually offered by the network itself or by a third party service provider (SP) using location data acquired from the users. This paper provides a rigorous theoretical and experimental analysis of the existing solutions for the location privacy problem in proximity services. This is a serious problem for users who do not trust the SP to handle their location data, and would only like to release their location information in a generalized form to participating buddies. The paper presents two new protocols providing complete privacy with respect to the SP, and controllable privacy with respect to the buddies. The analytical and experimental analysis of the protocols takes into account privacy, service precision, and computation and communication costs, showing the superiority of the new protocols compared to those appeared in the literature to date. The proposed protocols have also been tested in a full system implementation of the proximity service.
Female Cabbage Looper Sex Pheromone Attracts Male Scirtes orbiculatus F.12 (1981)

The lepidopteran sex pheromone Z-7-dodecenyl acetate specifically attracts male Scirtes orbiculatus beetles in large numbers. In trials over five seasons carried out at different locations near Urbana, Ill., no beetles were caught in traps baited with equivalent quantities of six closely related synthetic acetate esters of C12 to C18 unsaturated alcohols, or with an epoxide, synthetic racemic disparlure.
Fluorescent Deazaflavin-Oligonucleotide Probes for Selective Detection of DNA (2002)

Starke Fluoreszenzlöschung beobachtet man sowohl in Lösung als auch auf einer Glasoberfläche bei der Hybridisierung von Desazaflavin-Oligonucleotid-Konjugaten (siehe Bild, N&=Nucleosid) mit einem komplementären Strang. Dies könnte den Weg zu einem neuartigen DNA-Mikroarray bereiten, in dem der Fluorophor sich an der Sonde und nicht am Analytmolekül befindet. Der Vorteil wäre die mögliche Kontrolle der Qualität des Arrays.
OUT-OF-PLANE PROPAGATION IN PHOTONIC QUASI-CRYSTALS: GUIDED RESONANCES (2011)

This chapter deals with the out-of-plane electromagnetic wave propagation in aperiodically-ordered “photonic quasi-crystals” (PQCs). With specific reference on PQC slabs based on the quasi-periodic, 8-fold-symmetric Ammann-Beenker geometry, we review a body of results from our recent studies. More specifically, we study via full-wave numerical simulations the excitation of "guided resonances" in defect-free and point-defected supercells, by looking at the transmittance response for normally-incident plane-wave excitation as well as at the modal structure, and highlighting similarities and differences with respect to the standard periodic case. Finally, we address the fabrication-related issues, and present some preliminary experimental results at infrared wavelengths.
ChemInform Abstract: Chlorosulphamation of Acetylenes. (1986)

Abstract The N‐chloroamines (I) react with SO 3 (o form the known and highly reactive chlorosulphamates (II).
Simulation of Density Multiplication by Directed Self Assembly of PS-PMMA Block Copolymers. (2011)

Abstract not provided.
Contact Erosion at the Interface between Granular Coarse Soil and Various Base Soils under Tangential Flow Condition (2009)

Under embankment dams and dykes, horizontal groundwater seepage prevails. If the subsoil is layered, and if some coarse layers are not appropriate filters for finer layers, there can be contact erosion at the interface between fine and coarse soils. In order to study contact erosion threshold, some base-soil and coarse-soil combinations were submitted to a flow parallel to the interface between the coarse soil and the base soil. Critical velocities and critical hydraulic gradients were measured for various base soils. Using effective base-soil grain diameter, an empirical expression for critical velocity was proposed that is well adapted for silts or sand/clay mixtures as well as for sands. The mass of eroded soil was measured relative to the flow velocity for each base-soil/coarse-soil setup. The shear stress applied to the interface between base soil and coarse soil was derived from the hydraulic gradient. Using an empirical relationship between applied shear stress and measured eroded mass, erosion rate was estimated for each base-soil/coarse-soil setup.
COMO OS CONSUMIDORES PERCEBEM A PRESENÇA DO CANIBALISMO NO SETOR AUTOMOBILÍSTICO (2010)

Este trabalho poe em questao a percepcao do consumidor em relacao a pratica do canibalismo na industria automobilistica. O tema, que e pouco abordado em marketing desperta o interesse pela pesquisa. Com o objetivo de identificar uma possivel relacao entre as estrategias desenvolvidas pelas montadoras e os resultados efetivos sob os consumidores, foi feito um levantamento dos dados por meio de amostras no formato “grupos de foco”, definidos pela idade e sexo, uma vez que cada perfil tem influencias diferentes na tomada de decisao. Os dados coletados foram trabalhados com analise de conteudo por categorizacao. Por meio destas analises foi possivel identificar como o consumidor percebe a presenca do canibalismo, assim como o mesmo pode causar influencia na tomada de decisao. Amparado pelo referencial teorico, o resultado da pesquisa demonstra que cada grupo possui um perfil diversificado para visualizar o mercado e a pratica do canibalismo no setor automobilistico.