gebhart/patrepeval huggingface dataset:
Application of High Temperature Materials Thermodynamics to Room-Temperature Pourbaix Diagrams for Multi-component Systems (2013)

高温化学で用いる多元系に対する一般化された化学ポテンシャル図は異種材料間界面を含む種々の材料挙動を吟味する上で貴重な情報を提供する．この方法をプールベ（Pourbaix）線図を使って解析される室温化学に直接適用することはできないが，高温化学と室温化学との違いを生じさせている核形成・拡散などの速度論的過程に対する考察を導入することで，固液平衡が取り扱えるようになるということがキーポイントである．多元系プールベ線図を構築する新たな戦略を提示し，相合（congruent）溶解過程の重要性を示す．リチウム電池などの電気化学的過程への応用を興味深い一例として示す．
Dexamethasone Effects on Rat Hepatocyte Spheroid Formation and Function (2005)

Hepatocytes cultured on moderately adhesive surfaces or in spinner flasks spontaneously self-assemble into spherical tissue-like aggregates (spheroids). These spheroids have smooth surfaces and tissue-like polarized cell morphology, including bile canalicular-like channels, and maintain high viability and liver-specific functions for extended culture periods. Dexamethasone (DEX), a synthetic glucocorticoid, is known to elicit various responses in gene expression, and is often added to hepatocyte culture medium. The morphology and liver-specific protein production of hepatocyte spheroids were assessed under DEX concentrations ranging from 50 nM to 10 microM. DEX altered the kinetics of spheroid formation in a concentration-dependent fashion, with increasing concentrations inhibiting aggregation and promoting aggregate disassembly on culture dishes. DEX addition to spinner cultures resulted in smaller, more irregularly shaped spheroids and a higher incidence of aggregate clumping. Albumin and urea production were also higher in DEX cultures, but this effect was not as sensitive to concentration and occurred irrespective of the state of aggregation. RTPCR was utilized to assess the mRNA levels of extracellular matrix proteins, E-cadherin, and cytochrome P-450 enzymes. Results indicated a slight increase in fibronectin and collagen III mRNA early in the cultures, possibly contributing to the changes in morphology observed.
Using a cold radiometer to measure heat loads and survey heat leaks (2014)

We have developed an inexpensive cold radiometer for use in thermal/vacuum chambers to measure heat loads, characterize emissivity and specularity of surfaces and to survey areas to evaluate stray heat loads. We report here the results of two such tests for the James Webb Space Telescope to measure heat loads and effective emissivities of 2 major pieces of optical ground support equipment that will be used in upcoming thermal vacuum testing of the Telescope.
Digital holographic microscopy for label-free in vitro cytotoxicity testing of polymeric nanocarriers: an interlaboratory comparison (2023)

Digital holographic microscopy (DHM) has been demonstrated to be a suitable label-free and non-invasive quantitative phase imaging (QPI) tool in risk assessment of the cytotoxic potential of engineered nanoparticles and organic nanocarriers. For a broader application, robustness of DHM-based assays needs to be demonstrated towards DHM standardization in risk assessment. Thus, we performed an interlaboratory comparison on the transferability and reproducibility of a DHM-based assay. The cytotoxic potential of organic nanoparticles on A549 lung epithelial cells was analyzed in two European laboratories using identically constructed DHM systems. Our results demonstrate a solid and accurate performance of the DHM-based cytotoxicity assay
A fast and area efficient complimentary pass-transistor logic carry-skip adder (2002)

A two-level carry-skip adder using complementary pass-transistor logic is presented in this paper. The proposed adder is fast, area efficient and highly modular. It is compared with a two-level carry-skip adder using CMOS logic, and with a carry-lookahead adder automatically generated with the ALLIANCE CAD tools. SPICE simulations of the circuit extracted from the layout are used to evaluate the adder delay, while switch-level simulations are used to evaluate average power dissipation.
29Si NMR of aqueous silicate complexes at gigapascal pressures (2018)

Abstract Geochemists have models to predict solute speciation and mineral equilibria in aqueous solutions up to 1200 °C and 6 GPa. These models are useful to uncover reaction pathways deep in the Earth, though experimental confirmation is extremely difficult. Here we show speciation changes among aqueous silicate complexes to pressures of 1.8 GPa through use of a high-pressure solution-state NMR probe. The radiofrequency circuit uses a microcoil geometry that is coupled with a piston-cylinder pressure cell to generate and maintain these high pressures. The 1.8 GPa pressure corresponds to pressures reached at the lower crust or upper mantle. Although these experiments are limited to ambient temperature, we show that the increased pressure affects complexation and oligomerization reactions by eliminating bulk waters and that the pressure effects are completely reversible.
Effective Prediction of Job Processing Times in a Large-Scale Grid Environment (2006)

Grid applications that use a considerable number of processors for their computations need effective predictions of the expected computation times on the different nodes. Currently, there are no effective prediction methods available that satisfactorily cope with those ever-changing dynamics of computation times in a grid environment. Motivated by this, in this paper we develop the dynamic exponential smoothing (DES) method to predict job processing times in a grid environment. To compare predictions of DES to those of the existing prediction methods, we have performed extensive experiments in a real large-scale grid environment. The results illustrate a strong and consistent improvement of DES in comparison with the existing prediction methods
Microviscosity of native and reassembled lipoproteins (1977)

"Microviscosity of native and reassembled lipoproteins." Archives Internationales de Physiologie et de Biochimie, 85(5), pp. 1014–1015
Peroral Infection with Group B Coxsackievims in the Adult Mouse: Protective Functions of the Gut (1974)

Journal Article Peroral Infection with Group B Coxsackievims in the Adult Mouse: Protective Functions of the Gut Get access Roger M. Loria, Roger M. Loria From the Departments of Microbiology and Pediatrics, Boston University School of Medicine, Boston, Massachusetts Search for other works by this author on: Oxford Academic PubMed Google Scholar Sidney Kibrick, Sidney Kibrick From the Departments of Microbiology and Pediatrics, Boston University School of Medicine, Boston, Massachusetts Search for other works by this author on: Oxford Academic PubMed Google Scholar Selwyn A. Broitman Selwyn A. Broitman From the Departments of Microbiology and Pediatrics, Boston University School of Medicine, Boston, Massachusetts Search for other works by this author on: Oxford Academic PubMed Google Scholar The Journal of Infectious Diseases, Volume 130, Issue 5, November 1974, Pages 539–543, https://doi.org/10.1093/infdis/130.5.539 Published: 01 November 1974 Article history Received: 15 January 1974 Revision received: 28 May 1974 Published: 01 November 1974
Mobile Thin-Client System with Fault Tolerance and Scalability by "HTTP-FUSE-KNOPPIX-BOX". (2007)

We have developed a mobile thin-client server named ”HTTP-FUSE-KNOPPIX-BOX” that incorporates mechanisms for increasing performance, distributing load, and providing fault tolerance to achieve a practical HTTP-FUSE-KNOPPIX-based thin-client environment for mobile systems and other environments with limited hardware resources such as CPU and memory. Software RAID raises file input/output performance and RAID redundancy improves fault tolerance. Furthermore, the application of an improved version of DNS-Balance distributes server load and provides fault tolerance by automatically detecting server faults and dynamically switching client servers as needed. The HTTP-FUSE-cloop has also been optimized for embedded environments so that a thin-client environment can be provided in diverse usage scenarios. Evaluation of HTTP-FUSE-KNOPPIX-BOX has shown that its performance holds up to existing thin clients even in a server environment with limited CPU, memory, and other hardware and that system operation can continue in the event of faults without the user being conscious
CHARACTERIZATION OF PLASTICIZED CMC-NH4BR BASED BIOPOLYMER ELECTROLYTE AND ELECTROCHEMICAL STUDIES ON THE SOLID-STATE BATTERIES (2015)

Much research has been devoted to the preparation of solid polymer electrolytes made of various materials. Some of the wellknown are synthetic polymer materials (petroleum resources) but these polymers are high in cost and the depletion of petroleum resources coupled with increasing environmental regulation. For these reasons, a lot of effort has been made to develop the electrolytes using natural biopolymer materials. The increasing interest in green energy storage materials for electrochemical devices with the development of polymer as electrolytes candidate has attracted great attention recently. It can offer a number of high-value opportunities, provided that lower costs can be obtained besides environmental friendly. Due to this matter, the development of plasticized biodegradable polymer electrolytes (BPEs) has been accomplished in this work by incorporating various composition of EC with carboxy methylcellulose doped NH4Br via solution casting method. The plasticized polymer– salt complex formation and ionic conduction of BPEs have been analyzed through infrared spectroscopy and impedance measurement. Plasticization using EC in BPEs system helps the enhancement of NH4Br dissociation and therefore increases the protonation process in the system. The highest ionic conductivity obtained for CMC−NH4Br containing with 25 wt. % NH4Br was achieved at 1.12 x 10 -4 S cm -1 and enhanced to 3.31 x 10 -3 S cm -1 with addition of EC. The conductivity-temperature for BPEs system obeys the Arrhenius relation where the ionic conductivity increases with temperature. The electrochemical cell were fabricated with the configuration of Zn + ZnSO4.7H2O | BPEs system | MnO2 for the highest conductivity and produced a maximum open circuit voltage of 1.48 V at ambient temperature and showed good rechargeability.
DICER1 Syndrome and Cancer Predisposition: From a Rare Pediatric Tumor to Lifetime Risk (2021)

DICER1 syndrome is a rare genetic condition predisposing to hereditary cancer and caused by variants in the <i>DICER1</i> gene. The risk to present a neoplasm before the age of 10 years is 5.3 and 31.5% before the age of 60. <i>DICER1</i> variants have been associated with a syndrome involving familial pleuropulmonary blastoma (PPB), a rare malignant tumor of the lung, which occurs primarily in children under the age of 6 years and represents the most common life-threatening manifestation of DICER1 syndrome. Type I, II, III, and Ir (type I regressed) PPB are reported with a 5-year overall survival ranging from 53 to 100% (for type Ir). <i>DICER1</i> gene should be screened in all patients with PPB and considered in other tumors mainly in thyroid neoplasms (multinodular goiter, thyroid cancer, adenomas), ovarian tumors (Sertoli-Leydig cell tumor, sarcoma, and gynandroblastoma), and cystic nephroma. A prompt identification of this syndrome is necessary to plan a correct follow-up and screening during lifetime.
Salivary excretion of drugs. Part XVI. Inter-organ relation between salivary gland and kidney in lithium excretion. III. Enhanced salivary and systemic clearance of Li+ by oral administration of NaCl in dogs. (1990)

Effects of oral administration of NaCl on salivary and systemic clearance of Li+ were investigated following bolus intravenous administration of LiCl in male beagle dogs. Fifty ml of NaCl solution (100 meq/l) was administered orally 7 times at 1 h intervals. Gustatory stimulation of salivation was continued for 390 min using citric acid solution. Saliva was collected by means of permanent fistulae for parotid and mandibular-sublingual glands. Salivary clearance of Li+ was markedly increased by continuous stimulation of salivation, and was enhanced further after oral administration of NaCl solution. Renal clearance of Li+ showed a decreasing tendency under continuous salivation compared with the condition without gustatory stimulation; however, this decreasing tendency disappeared after oral administration of NaCl solution. Consequently, systemic clearance of Li+ was increased due to the contribution of increased salivary clearance. Enhancement of salivary Li+ clearance after administration of NaCl suggests the salivary excretion mechanism of Li+ may include a reabsorption process, like its renal excretion. Administration of NaCl solution had similar effects on salivary and systemic clearances of K+ to those on Li+ clearances, and a significant correlation was observed between Li+ and K+ clearances of both salivary gland and kidney.
Modulation characteristics of cw laser diodes (1976)

Lightwave communication systems employing junction lasers as sources are currently being evaluated in realistic field environments around the World. In many respects, a laser diode is an ideal source for these systems since it emits adequate power for economical fiberguide transmission and is compatible with fibers integrated optics, and integrated circuits, efficient in its conversion of electrical to optical power, mechanically rugged, potentially reliable, and easily modulated in a variety of ways. This paper reviews the modulation characteristics of contemporary cw junction lasers with a view to identifying current limitations on their performance. We focus on the (AlGa)As double-hereto-structure (DH) diode fabricated in a stripe-geometry since this device is the most developed for fiberguide systems.
Concentration and Purification of Viruses by Adsorption to and Elution from Insoluble Polyelectrolytes (1971)

Acid-resistant, nonenveloped viruses belonging to the enterovirus, reovirus, and adenovirus groups were readily concentrated on PE60, an insoluble cross-linked polyelectrolyte based on isobutylene maleic anhydride. Hydrolysis of PE60 by NaOH increased its capacity to adsorb viruses. Hydrogen ion levels played an important role in virus concentration; optimal pH levels for maximal virus adsorption were between pH 3.0 and 4.5. Undiluted virus was easily concentrated from large volumes on PE60, and the adsorbed virus was readily eluted at pH 8 to 9.
Choice and Improvement of Superior Genetic Stocks of Senna (<i>Cassia angustifolia</i>) (1992)

AbstractUseful statistical and genetic parameters were developed in 49 germplasm collections of senna obtained from different states of India. Genetic variability was high for pod and seed yields but moderate for leaf yield. Broad sense heritability was also high for all traits except number of branches. The three important traits. viz., dry leaf yield, dry pod yield and seed yield manifested high h2BS coupled with high GA and the latter two traits were favourably correlated as well. hence most amenable for straight selection. Potentially superior parents were also identified for genetic improvement of senna.
Amino acid sequence and tertiary structure of Cratylia mollis seed lectin (2003)

Carbohydrate-protein interactions play a key role in many biological processes. Cramoll is a lectin purified from Cratylia mollis seeds that is taxonomically related to concanavalin A (Con A). Although Cramoll and Con A have the same monosaccharide specificity, they have different glycoprotein binding profiles. We report the primary structure of Cramoll, determined by Edman degradation and mass spectrometry and its 1.77 A crystallographic structure and compare it with the three-dimensional structure of Con A in an attempt to understand how differential binding can be achieved by similar or nearly identical structures. We report here that Cramoll consists of 236 residues, with 82% identity with Con A, and that its topological architecture is essentially identical to Con A, because the Calpha positional differences are below 3.5 A. Cramoll and Con A have identical binding sites for MealphaMan, Mn2+, and Ca2+. However, we observed six substitutions in a groove adjacent to the extended binding site and two in the extended binding site that may explain the differences in binding of oligosaccharides and glycoproteins between Cramoll and Con A.
Prediction of Flow-Induced Noise Sources of Wind Turbines and Application Examples (2015)

The consideration of aeroacoustic aspects and the minimization of noise emission is an integral part in the design process of modern onshore wind turbines. In the present paper dedicated aeroacoustic prediction methods are introduced that are applied at the University of Stuttgart for identification of noise sources and the aero-acoustic design and analysis of airfoils and rotors of wind turbines. The available portfolio of tools ranges from fast semi-empirical methods to numerical CAA schemes with substantial computational demands. The chain of tools thereby enables a separation and quantitative comparison of the different relevant noise sources. Based on dedicated wind tunnel measurements of noise sources and noise emission of airfoils the methods have been continuously verified and improved. Besides a summary of the theoretical basis, specific validation examples are given that show the strengths and the deficiencies of the available methods and motivate ongoing improvements. Finally, application examples with practical relevance and means for a passive and active noise reduction are discussed.
In vitro characterization of aldosterone and cAMP effects in mouse distal convoluted tubule cells (2004)

The distal nephron plays a capital role in the fine regulation of sodium reabsorption. Compared with the cortical collecting duct, much less information is available on the hormonal regulation of sodium transporter genes in the distal convoluted tubule (DCT), where the thiazide-sensitive Na(+)-Cl(-) cotransporter (NCC) is the major entry pathway for Na(+). The purpose of this study was to characterize the in vitro effects of aldosterone (Aldo; 1 microM) and cAMP (8-BrcAMP; 0.5 mM) on mouse DCT (mDCT) by using an immortalized mDCT cell line. Western blot analysis and semiquantitative RT-PCR were performed to analyze the expression of genes involved in sodium transport. The mDCTcell line expressed the 11 beta-hydroxysteroid dehydrogenase type 2 gene and both the mineralocorticoid and glucocorticoid receptor genes, suggesting Aldo responsiveness. In this sense, we found that mDCT cells expressed the amiloride-sensitive Na(+) channel (ENaC) and responded to Aldo by upregulating the alpha-subunit protein. Similarly, alpha(1) Na(+)-K(+)-ATPase protein was upregulated by Aldo and 8-BrcAMP. In addition, the Aldo intermediate gene sgk1 mRNA was increased in response to both Aldo and 8-BrcAMP, and the transcription factor HNF-3 alpha mRNA was induced by 8-BrcAMP. With respect to NCC regulation, although Aldo induced NCC protein levels in mice in vivo, neither Aldo nor 8-BrcAMP significantly induced the NCC mRNA or protein levels in mDCT cells. These results suggest that in mDCT, Aldo and cAMP modulate some downstream mediators and effectors in vitro but do not influence the expression of NCC in this cell model.
Synthesis and Electrical Properties of La Doped SrTiO<sub>3</sub> Powders by Ultrasonic Spray Pyrolysis (2013)

La-doped SrTiO 3 (LST) powders were synthesized by ultrasonic spray pyrolysis using an aqueous solution of a metal nitrate. SEM images showed that the as-prepared LST powders had a spherical morphology with a diameter of 1 μm. XRD patterns showed that the crystal phase of the as-prepared powders was amorphous and that the powders crystallized to the perovskite phase by calcination at 900 °C. The sintered LST body had the highest electrical conductivity at a La doping concentration (La x ) of 0.1 under a reducing atmosphere. A solid oxide fuel cell (SOFC) with La 0.1 Sr 0.9 TiO 3 Sm-doped CeO 2 (1:9) as the anode exhibited a maximum power density of 137.8 mW/cm 2 and an open circuit voltage of 1.08 V at 880 °C.
Methylazoxymethanol Acetate-induced Apoptosis in the External Granule Cell Layer of the Developing Cerebellum of the Rat Is Associated with Strong c-Jun Expression and Formation of High Molecular Weight c-Jun Complexes (1997)

Intraperitoneal administration of methylazoxymethanol (MAM) acetate (0.05 microl/g of body weight) in male Sprague-Dawley rats aged 3 days produced cell death in the external granule layer of the cerebellum which peaked at 48 hours (h) and was followed by removal of cellular debris at 72 h. Dying cells had the morphological features of apoptosis and were stained with the method of in situ labeling of nuclear DNA fragmentation. Strong c-Jun immunoreactivity was observed in apoptotic cells during the whole process of MAM-induced apoptosis. No differences of c-Fos immunoreactivity were observed between control and MAM-treated rats throughout the period studied. Western blotting of cerebellar homogenates in control rats disclosed two bands which reacted with both c-Jun antibodies, one located at p39 that corresponds to the molecular weight of c-Jun, and the other at about p62. MAM-treated rats showed a robust band at p62, together with a thinner band located immediately above it, which was accompanied by a reduction of the p39 band. The specificity of the immunoreaction was tested by incubating the antibodies with the appropriate control peptides. No difference between control and MAM-treatad rats was observed in Western blots processed with antibodies to c-Fos during this study. These results show that MAM-induced apoptosis in the external granule cell layer of the rat is associated with strong c-Jun expression, which is restricted to apoptotic cells, and with the formation of high-molecular-weight c-Jun complexes. Taken together, the present observations suggest that c-Jun may participate in the genetic cascade of events leading to apoptotic cell death in the developing cerebellum.
Perillyl alcohol induces apoptosis in human glioblastoma multiforme cells (2005)

Standard treatment of glioblastoma multiforme consisting of surgical resection, radiation and/or chemotherapy is rarely curative, emphasizing the need for new chemotherapeutic drugs. The monoterpene perillyl alcohol (POH) has preventive and therapeutic effects in a wide variety of pre-clinical tumor models and is currently under phase I and II clinical trials. In the present study, we analyzed its effect on human glioblastoma cell lines (U87 and A172) and a primary cell culture derived from a human glioblastoma tumor specimen (GBM-1). Using MTT, we showed that POH inhibits the viability of glioblastomas in a concentration-dependent way. Glioblastoma cell lines treated with POH showed morphological alterations characteristic of apoptosis. Analysis of cell cycle and quantification of DNA fragmentation, in cells stained with propidium iodide (PI), confirmed the apoptotic effect of POH on glioblastomas. These data support the potential usefulness of perillyl alcohol as an effective chemotherapeutic agent for patients with recurrent glioblastoma multiforme.