gebhart/patrepeval huggingface dataset:
Late complications of fractures of the calcaneus. (1993)

We retrospectively reviewed the results of the operative treatment of forty-three fractures of the calcaneus in forty-two patients (thirty-six men and six women). The operations had been performed a mean of twenty-six months (range, six to seventy-two months) after the injury. An in situ subtalar arthrodesis had been performed in fifteen patients; a subtalar distraction bone-block arthrodesis, in fourteen; a triple arthrodesis, in five; a lateral calcaneal ostectomy, in seven; a transection and proximal transposition of the sural nerve, in seven; and a release of the tibial nerve, in five. The patients were examined at a mean of thirty-two months (range, twenty-six to fifty-two months) after the operation. The difference between the preoperative and postoperative rating scores was used to measure any improvement in function. Pain was partially relieved in thirty-eight (90 per cent) of the patients, function improved in thirty-five (83 per cent), and thirty-two (76 per cent) of the patients returned to work or to a pre-injury level of activity at a mean of eight months (range, four to sixteen months) after the operation. There was a trend (p = 0.07) that the longer the interval between the injury and the operation, the longer the subsequent interval until the patient returned to full activities or work. The most successful results were in the patients who had had a subtalar arthrodesis.
Limiting MitM to MitE Covert-Channels (2013)

We study covert channels between a MitM attacker, and her MitE 'malware', running within the protected network of a victim organisation, and how to prevent or limit such channels. Our focus is on advanced timing channels, that allow communication between the MitM and MitE, even when hosts inside the protected network are restricted to only communicate to other (local and remote) hosts in the protected network. Furthermore, we assume communication is encrypted with fixed packet size (padding). We show that these do not suffice to prevent covert channels between MitM and MitE; furthermore, we show that even if we restrict communication to a constant rate, e.g., one packet everysecond, communication from MitE to MitM is still possible.We present efficient traffic shapers against covert channels between MitM and MitE. Our solutions preserve efficiency and bounded delay (QoS), while limiting covert traffic leakage, in both directions.
A new alloplastic material for ophthalmic surgery. (1978)

The application of Proplast in ocular surgery is in an early stage. We believe our preliminary work may offer a solution to the problem of erosion and slippage common to other types of implants. We are currently investigating the potential of Proplast in keratoprosthesis. Proplast may prove useful in buckles and implants for retina detachment as well as stabilizing splints for blow-out fractures. Proplast is an inert, carbon and Teflon alloplast, not previously described in the ophthalmic literature. Corneal and scleral implants in rabbits are well tolerated. Proplast is porous and microscopic examination of the implants show fibrovascular ingrowth within its matrix, thereby incorporating it into the host tissue. The rate at which the implant is incorporated by host tissue ingrowth and the long-term acceptance of the alloplast have yet to be determined.
Homogeneous light‐induced electron transfer between 9,10‐anthracenedione and sodium tetraphenylborate: A channel electrode study (1991)

Abstract The electron transfer between excited‐state 9,10‐anthracenedione (325 nm) and sodium tetraphenylborate (tetraphenylboron sodium) in acetonitrile solution is shown to form the radical anion of 9,10‐anthracenedione together with the BPh radical. The latter is known to decompose to biphenyl and other Products. A new channel electrode methodology is developed and characterized to deduce the mechanism of the reaction and to quantify its kinetics.
Analysis and Modeling of Lead Coplanarity Distributions (1996)

Lead coplanarity is defined as the height of a packaged device lead above the seating plane on which the device rests. The yield of a mass reflow surface mount soldering assembly process depends on lead coplanarity since, clearly, an excessive coplanarity is likely to produce an “open” between the lead and circuit pad. Furthermore, even if a marginal joint is obtained, excessive coplanarity can lead to reliability problems. Since these issues become more important as lead sizes decrease and pitches are refined, it is important to achieve a better understanding of coplanarity. This report analyzes the nature of 86,016 coplanarity measurements of 0.4 mm pitch, 256 I/O QFP devices. Four components to the coplanarity are identified and the distribution of each is modeled. When the four components are recombined, the result is a probability distribution for coplanarity. This information is required as input to an assembly yield model where parameter variations and tolerances are analyzed to predict surface mount yields.
Additions and Corrections - Steric Hindrance to the Formation of and Protonation of the Nitronate Ion from 2-Aryl-1-nitrocyclohexanes. (1967)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAdditions and Corrections - Steric Hindrance to the Formation of and Protonation of the Nitronate Ion from 2-Aryl-1-nitrocyclohexanes.F. G. Bordwell and Martha M. VestlingCite this: J. Am. Chem. Soc. 1967, 89, 18, 4817Publication Date (Print):August 1, 1967Publication History Published online7 May 2004Published inissue 1 August 1967https://pubs.acs.org/doi/10.1021/ja00994a606https://doi.org/10.1021/ja00994a606research-articleACS PublicationsRequest reuse permissionsArticle Views21Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Opacification of a hydrophilic acrylic intraocular lens with exacerbation of Behçet's uveitis (2002)

Behçet's disease is 1 of the most common causes of uveitis in the Eastern world. Its common ocular complications are uveitis, cataract, and obliteration of retinal vessels. Phacoemulsification with intraocular lens (IOL) implantation in patients with Behçet's disease is known to be a safe procedure. We managed a patient with Behçet's disease who had aggravated uveitis and opacification of a hydrophilic acrylic IOL (ACRL-C160, Ophthalmed) 4 months after cataract surgery. Recalcitrant uveitis despite maximum tolerable medication and IOL opacification with vitreous opacity necessitated an IOL exchange and trans pars plana vitrectomy. After the procedure, the eye became quiescent. However, the visual acuity was 20/200 because of the obliteration of retinal vessels.
Telegraph noise due to domain wall motion driven by spin current in perpendicular magnetized nanopillars (2009)

Telegraph noise induced by stochastic domain wall nucleation, pinning, and annihilation in the presence of spin transfer torque is observed in nanopillar spin valves with perpendicular anisotropy. By measuring the dwell times corresponding to domain wall pinning and to domain wall nucleation, the telegraph noise is found to be consistent with thermal activation over an effective potential barrier.
Secondary jaw crusher development (1974)

burner. Analysis of the work is provided and recommendations are made for future applications in larger burners.
3.17-THz frequency-difference measurement between lasers using two optical frequency combs (1996)

In order to increase the signal-to-noise ratio in the measurement of frequency-difference between two lasers by using an optical frequency comb generator (OFC-G), two laser beams were combined into the OFC-G. Then many sidebands that contribute to the beat signal generation were generated. We observed the spectrum of the beat signal with a signal-to-noise ratio of 30 dB when the frequency-difference between two lasers was 3.17 THz.
Cardiac and respiratory responses during visual search in nonretarded children and retarded adolescents. (1977)

The relationship between physiological response patterns and mental competence was investigated by evaluating heart rate and respiratory responses during a sustained visual-search task in nonretarded grade school children and retarded adolescents. The findings support the contention that, during tasks demanding sustained attention, retarded relative to nonretarded individuals exhibit physiological responses that parallel their poor performance. Consistent with previous research with nonretarded adults, the nonretarded grade school children exhibited a suppression of respiratory and heart-rate variability during attention-demanding tasks. In contrast, the retarded adolescents exhibited increases in respiratory and heart-rate variability. These qualitative differences in physiological and behavioral responses, observed during sustained attention, may be viewed as a manifestation of retarded adolescents' defective nervous system.
Quercetin induces hepatic lipid omega-oxidation and lowers serum lipid levels in mice [Mus Musculus] (2013)

Elevated circulating lipid levels are known risk factors for cardiovascular diseases (CVD). In order to examine the effects of quercetin on hepatic lipid metabolism and detailed serum lipid profiles, mice received a mild-high-fat diet without (control) or with supplementation of 0.33% (w/w) quercetin for 12 weeks. Gas chromatography and 1H nuclear magnetic resonance were used to measure quantitatively serum lipid profiles and whole genome microarray analysis was used to identify the responsible mechanisms in liver. There were no significant differences found in mean body weight, energy intake and hepatic lipid accumulation between the quercetin and control group. In serum of quercetin-fed mice, TG levels were decreased with 15%, poly unsaturated fatty acids (PUFA) were increased with 14% and saturated fatty acids were decreased. Palmitic acid, oleic acid, and linoleic acid were all decreased in quercetin-fed mice by 9-15%. Both palmitic acid and oleic acid can be oxidized by omega-oxidation. Indeed, gene expression profiling showed that quercetin increased hepatic lipid metabolism, especially omega-oxidation. At the gene level, this was reflected by the up regulation of cytochrome P450 (Cyp) 4a10, Cyp4a14, Cyp4a31 and Acyl-CoA thioesterase 3 (Acot3). Two relevant regulators, Cytochrome P450 oxidoreductase (Por, rate limiting for cytochrome P450s) and the transcription factor Constitutive androstane receptor (Car; official symbol Nr1i3) were also up regulated in the quercetin-fed mice. We conclude that quercetin intake increased hepatic lipid omega-oxidation and lowered corresponding circulating lipid levels, a process that may involve Por and Car, and results in a potential beneficial CVD preventive effect.
Extracting Evidence Fragments for Distant Supervision of Molecular Interactions (2017)

Abstract. We describe a methodology for automatically extracting ‘evidence fragments’ from a set of biomedical experimental research articles. These fragments provide the primary description of evidence that is presented in the papers’ figures. They elucidate the goals, methods, results and interpretations of experiments that support the original scientific contributions the study being reported. Within this paper, we describe our methodology and showcase an example data set based on the European Bioinformatics Institute’s INTACT database ( http://www.ebi.ac.uk/intact/ ). Using figure codes as anchors, we linked evidence fragments to INTACT data records as an example of distant supervision so that we could use INTACT’s preexisting, manually-curated structured interaction data to act as a gold standard for machine reading experiments. We report preliminary baseline event extraction measures from this collection based on a publicly available, machine reading system (REACH). We use semantic web standards for our data and provide open access to all source code.
Efficacy of 5-aminolevulinic acid-mediated photodynamic therapy using light-emitting diodes in human colon cancer cells (2013)

5-Aminolevulinic acid (ALA)-mediated photodynamic therapy (PDT) (ALA-PDT) is a highly selective treatment for malignant cells. ALA-PDT has the potential to develop into a novel therapeutic strategy for various types of cancer. Recently, light-emitting diodes (LEDs), which are inexpensive, stable and easier to handle compared to lasers, have been used in PDT as a light source. However, in colorectal cancer (CRC), the efficacy of ALA-PDT in combination with LEDs has not been fully assessed. Therefore, in this study, we evaluated the antitumor effect of ALA-PDT using various LEDs in colon cancer cells. The HT-29 human colon cancer cell line was used both in vitro and in vivo. HT-29 cells were seeded in 96-well plates. Following 5-ALA administration, cells were irradiated using LEDs at different wavelengths. Three types of LEDs, blue (peak wavelength, 456 nm), white (broad-band) and red (635 nm) were used. Twenty-four hours after irradiation, the cytotoxic effects of ALA-PDT were measured using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay. In order to evaluate the antitumor effect of ALA-PDT in vivo, nude mice were inoculated with HT-29 cells. Xenograft mice were injected intraperitoneally with 5-ALA and irradiated with 3 types of LEDs at a measured fluence rate of 96 mW/cm2 and fluence of 32 J/cm2. Each group comprised 6 mice. ALA-PDT was repeated 3 times at weekly intervals. Tumor weights were measured. Compared to the controls, ALA-PDT using LEDs showed significant antitumor effects in vitro and in vivo. The blue and white LEDs demonstrated greater antitumor effects compared to the red LEDs in vitro and in vivo. In particular, tumor inhibition rates in the blue and white LED groups were approximately 88% to those of the control group in the mouse models. In conclusion, ALA-PDT using LEDs is effective and useful in the treatment of CRC cells. This method could be a novel treatment modality for CRC.
Hydrophilic interaction chromatography/electrospray mass spectrometry analysis of carbohydrate‐related metabolites from <i>Arabidopsis thaliana</i> leaf tissue (2008)

This work describes the development and application of an on-line liquid chromatography/mass spectrometry (LC/MS) method using hydrophilic interaction chromatography (HILIC) coupled to negative ion mode electrospray ionisation ion trap mass spectrometry (ESI-MS) for the analysis of highly polar carbohydrate-related metabolites commonly found in plants, ranging from reducing and non-reducing sugars and sugar alcohols to sugar phosphates. Using this method, separation and detection of a mixture of eight authentic standard compounds containing glucose (Glc), sucrose (Suc), raffinose, verbascose, mannitol, maltitol, glucose-6-phosphate (Glc6P) and trehalose-6-phosphate (Tre6P) were achieved in less than 15 min. The method is rapid, robust, selective, and sensitive, with limits of detection (LODs) ranging from 0.2 microM obtained for neutral sugars, to 1.0 microM obtained for sugar alcohols, and 2.0 microM obtained for negatively charged sugar phosphates. We have studied the negative ion collision-induced dissociation (CID) fragmentation behaviour of the non-reducing raffinose family oligosaccharides (RFOs) raffinose, stachyose, and verbascose. Mainly Bi and Ci glycosidic and Ai cross-ring structurally informative cleavages are observed. We have applied this HILIC/ESI-MS method for the analysis of Arabidopsis thaliana wild-type Columbia-0 (Col-0) and its starchless phosphoglucomutase mutant (pgm1) leaf extracts. The method was used to quantify Glc, Suc, raffinose, and Glc6P in A. thaliana extracts. Data obtained using this HILIC/ESI-MS method were compared with those obtained using a comparable porous graphitic carbon-based LC/ESI-MS method.
Boosting fuzzy rules with low quality data in multi-class problems: Open problems and challenges (2013)

Existing extensions of AdaBoost-based fuzzy rule learning to low quality databases yield suboptimal results in multi-class problems. A new procedure is proposed where the original multi-class database is transformed into several multi-label problems that can be tackled with binary AdaBoost. The performance of this proposal is assessed in comparison with other classification schemes for imprecise data. A novel experimental design for imprecise databases is introduced for this last purpose. The new algorithm is applied to a set of real-world and synthetic low quality datasets.
Boronated Monoclonal Antibody 225.28S for Potential Use in Neutron Capture Therapy of Malignant Melanoma (1989)

The concept of conjugating boron cluster compounds to monoclonal antibodies has been examined by several groups of research workers in boron neutron capture therapy (BNCT). The procedures reported to date for boronation of monoclonal antibodies resulted in either an inadequate level of boron incorporation, the precipitation of the conjugates, or a loss of immunological activity. The present report describes the conjugation of dicesium-mercapto-undecahydrododecaborate (Cs2B12H11SH) to 225.28S monoclonal antibody directed against high molecular weight melanoma-associated antigens (HMW-MAA), using poly-L-ornithine as a "bridge" to increase the carrying capacity of the antibody and to minimize change in the conformational structure of antibody. The method produces a boron content of 1,300 to 1,700 B atoms per molecule 225.28S while retaining the immunoreactivity. Characterization in terms of the homogeneity of the conjugation of the boron-monoclonal antibody conjugates has been studied by gel electrophoresis and ion-exchange HPLC.
GEO Fleet Operations with a Multi-Mission Satellite Control Center (2008)

HISPASAT Group is operating now four Satellites:1C, 1D, and SPAINSAT (to cover the demand of governmental services for the Spanish Ministry of Defense) in 30o West and Amazonas-1 in 61o West. In preparation to cover the emerging demand in 61o West, HISPASAT has under construction Amazonas-2 satellite, to be placed in 61o West along year 2009. Additional satellites are under study for both orbital positions in the plan to increase the available on orbit capacity. HISPASAT manages the Satellite Control Operations for Telemetry and Telecommand functions by using platform specific Satellite Control Centers (SCC), therefore having at the present stage three different SCC platfomrs. This approach is being revisited and HISPASAT’s philosophy is now oriented towards a more flexible and easy to operate concept that implies to integrate the satellite operations using a common control platform. That continues the trend already initiated with the Flight Dynamics with GMV’s focusGEO and will be complemented in the Satellite Control Center area with GMV’s hifly®.
A stronger patch test elicitation reaction to the allergen hydroxycitronellal plus the irritant sodium lauryl sulfate (2003)

Household and cleaning products often contain both allergens and irritants. The aim of this double-blinded, randomized, paired study was to determine whether patch testing with an allergen (hydroxycitronellal) combined with an irritant [sodium lauryl sulfate (SLS)] cause a stronger patch test elicitation reaction than patch testing with the allergen (hydroxycitronellal) alone, in patients previously patch tested positive to hydroxycitronellal. A stronger patch test elicitation reaction was defined as at least 1 day of patch test reading showing more positive patch tests (+, ++ or +++) on the forearm patch tested with 6 concentrations of SLS plus hydroxycitronellal than on the forearm tested with 6 concentrations of hydroxycitronellal alone and no day of patch test readings showing more positive tests on the hydroxycitronellal forearm. 15/20 (75%) had at least 1 day of patch test reading with more positive patch tests on the forearm patch tested with SLS plus hydroxycitronellal and no day of patch test readings with more positive patch tests on the forearm tested with hydroxycitronellal (P = 0.0253). Estimation of the blood flow with laser Doppler supported these findings.
Generic decoupled image-based visual servoing for cameras obeying the unified projection model (2009)

In this paper a generic decoupled imaged-based control scheme for calibrated cameras obeying the unified projection model is proposed. The proposed decoupled scheme is based on the surface of object projections onto the unit sphere. Such features are invariant to rotational motions. This allows the control of translational motion independently from the rotational motion. Finally, the proposed results are validated with experiments using a classical perspective camera as well as a fisheye camera mounted on a 6 dofs robot platform.
17-KETOSTEROID AND PITUITARY FOLLICLESTIMULATING HORMONE EXCRETION IN MYXEDEMA, BEFORE AND DURING TREATMENT WITH THYROXINE* (1954)

IN PATIENTS with myxedema, a decreased urinary excretion of 17-ketosteroids has been a uniform finding (1–4). Values under 3 mg. per day have been observed in women and under 7 mg. in men. The administration of desiccated thyroid to myxedematous patients has been reported to be ineffectual in restoring the excretion of steroids to normal, even when the clinical response to thyroid, including normalization of the basal metabolic rate and serum cholesterol level, was complete (1, 3, 5). Patients with hypothyroidism but without myxedema apparently have normal levels of urinary 17-ketosteroids (1). Several observers have found that in hyperthyroid persons the decrease in 17-ketosteroid excretion is not striking, the values being usually in the subnormal or low-normal range (1–4, 6). Satisfactory treatment of the hyperthyroidism is accompanied by a rise to normal of the 17-ketosteroids (1). No significant correlation has been noted between the clinical data, such as severity and duration of the thyrotoxic state, and the levels for urinary 17-ketosteroids (hereafter referred to as 17-KS).