gebhart/patrepeval huggingface dataset:
Characteristics and fatty acid composition of Brachychiton species seeds and the oils (Sterculiaceae) (1991)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCharacteristics and fatty acid composition of Brachychiton species seeds and the oils (Sterculiaceae)Koyyalamudi Sundar RaoCite this: J. Agric. Food Chem. 1991, 39, 5, 881–882Publication Date (Print):May 1, 1991Publication History Published online1 May 2002Published inissue 1 May 1991https://doi.org/10.1021/jf00005a014Request reuse permissionsArticle Views103Altmetric-Citations5LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (195 KB) Get e-Alertsclose Get e-Alerts
Src-mediated aryl hydrocarbon and epidermal growth factor receptor cross talk stimulates colon cancer cell proliferation (2012)

The aryl hydrocarbon receptor (AhR) mediates many toxic effects of environmental pollutants. AhR also interacts with multiple growth factor-driven signaling pathways. In the course of examining effects of growth factors on proliferation of human colon cancer cells, we identified cross talk between AhR and the epidermal growth factor receptor (EGFR). In the present work, we explored underlying signal transduction mechanisms and functional consequences of this interaction. With the use of two human colon cancer cell lines, H508 and SNU-C4, we examined the effects of AhR ligands including 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on cell proliferation and activation of EGFR, ERK1/2, and Src kinases. In colon cancer cells, 5-day incubation with TCDD stimulated a twofold dose-dependent increase in cell proliferation that was detectable with 1 nM and maximal with 30 nM TCDD. TCDD induced dose- and time-dependent phosphorylation of EGFR (Tyr845) and ERK1/2; maximal phosphorylation was observed 5 to 10 min after addition of 30 nM TCDD. Both TCDD-induced ERK1/2 phosphorylation and cell proliferation were abolished by AhR small interfering RNA, AhR-specific inhibitor CH223191, Src kinase inhibitor PP2, neutralizing antibodies against matrix metalloproteinase 7, heparin-binding-EGF-like growth factor and EGFR, EGFR inhibitors (AG1478 and PD168393), and MEK1 inhibitor PD98059. Coimmunoprecipitation experiments revealed that AhR forms a protein complex with Src and regulates Src activity by phosphorylating Src (Tyr416) and dephosphorylating Src (Tyr527). These data support novel observations that, in human colon cancer cells, Src-mediated cross talk between aryl hydrocarbon and EGFR results in ERK1/2 activation, thereby stimulating cell proliferation.
Stability and Structure of Mixed‐Ligand Metal Ion Complexes That Contain Ni <sup>2+</sup> , Cu <sup>2+</sup> , or Zn <sup>2+</sup> , and Histamine, as well as Adenosine 5′‐Triphosphate (ATP <sup>4−</sup> ) or Uridine 5′‐Triphosphate (UTP <sup>4−</sup> ): An Intricate Network of Equilibria (2011)

With a view on protein-nucleic acid interactions in the presence of metal ions we studied the "simple" mixed-ligand model systems containing histamine (Ha), the metal ions Ni(2+), Cu(2+), or Zn(2+) (M(2+)), and the nucleotides adenosine 5'-triphosphate (ATP(4-)) or uridine 5'-triphosphate (UTP(4-)), which will both be referred to as nucleoside 5'-triphosphate (NTP(4-)). The stability constants of the ternary M(NTP)(Ha)(2-) complexes were determined in aqueous solution by potentiometric pH titrations. We show for both ternary-complex types, M(ATP)(Ha)(2-) and M(UTP)(Ha)(2-), that intramolecular stacking between the nucleobase and the imidazole residue occurs and that the stacking intensity is approximately the same for a given M(2+) in both types of complexes: The formation degree of the intramolecular stacks is estimated to be 20 to 50%. Consequently, in protein-nucleic acid interactions imidazole-nucleobase stacks may well be of relevance. Furthermore, the well-known formation of macrochelates in binary M(2+) complexes of purine nucleotides, that is, the phosphate-coordinated M(2+) interacts with N7, is confirmed for the M(ATP)(2-) complexes. It is concluded that upon formation of the mixed-ligand complexes the M(2+)-N7 bond is broken and the energy needed for this process corresponds to the stability differences determined for the M(UTP)(Ha)(2-) and M(ATP)(Ha)(2-) complexes. It is, therefore, possible to calculate from these stability differences of the ternary complexes the formation degrees of the binary macrochelates: The closed forms amount to (65±10)%, (75±8)%, and (31±14) % for Ni(ATP)(2-), Cu(ATP)(2-), and Zn(ATP)(2-), respectively, and these percentages agree excellently with previous results obtained by different methods, confirming thus the internal validity of the data and the arguments used in the evaluation processes. Based on the overall results it is suggested that M(ATP)(2-) species, when bound to an enzyme, may exist in a closed macrochelated form only, if no enzyme groups coordinate directly to the metal ion.
Intracellular localization of the P21rho proteins. (1992)

The three mammalian ras proteins associated specifically with the plasma membrane and this is essential for their biological activity. Two signals encoded within the extreme COOH terminus of the proteins specify this cellular localization; a CAAX box in combination with either a polybasic domain (p21K-rasB) or a palmitoylation site (p21Ha-ras and p21N-ras). All members of the ras-like and rho-like subfamilies of the ras superfamily of small GTP-binding proteins also have CAAX boxes with potential second site sequences resembling either p21K-rasB or P21N-ras/Ha-ras. However it is not at all clear that they are each located at the plasma membrane, and in fact one of the ras-like proteins, rap1, has been localized to the Golgi (Beranger et al., 1991). None of the mammalian rho-like subfamily has yet been localized. Three forms (A, B, and C) of p21rho, the prototype of this family are known; the COOH termini of p21rhoA and p21rhoC resemble p21K-rasB with a polybasic domain, whereas p21rhoB resembles p21N-ras/Ha-ras with two cysteine residues as potential palmitoylation sites. Despite this similarity to the p21ras proteins, rho proteins have been purified from both particulate and cytosolic fractions of a variety of tissues. In order to localize definitively the three rho proteins we have used an epitope tagging approach coupled to microinjection of living cells. We show that a small fraction of all three proteins is localized to the plasma membrane but the majority of p21rhoA and p21rhoC is cytosolic whereas p21rhoB is associated with early endosomes and a pre-lysosomal compartment. Along with the results obtained with chimeric molecules using heterologous proteins attached to rho COOH termini, this suggests that the p21rho proteins cycle on and off the plasma membrane and this may have important implications for their biological function.
[Role of pH as a regulator of vaginal physiological environment]. (2000)

In the vagina there are several microorganisms. Their survival is fundamental to have a physiological environment in the vagina (ecosystem). The same vaginal environment playg a fundamental role to guarantee tho survival of resident microorganisms. Several factors, like changes of temperature and oxygenation, can interfere on vaginal ecosystem, but the resident vaginal microorganisms are the main factors to stabilize the vaginal ecosystem. The Doderlein's lactobacillus is the predominant vaginal microorganism. It is capable of fermenting the glycogen deriving from the decline of the eutrophic vaginal mmucosa, to lactic acid with release of hydrogen ions. The final result of that metabolism is an acid pH with values between 4-4.5. Vaginal pH undergoes physiologically changes from birth to menopause, according to changes of ovarian steroids occurring during woman's life. Adequate levels of estrogens play a fundamental role in the trophism of vaginal mucosa. In fact, estrogens increase the cellular content of glycogen. Exogenous acbvities on vaginal pH can be exerted by several factors, such as sexual activily, oral contraceptives, systemic diseases, vaginal infections (candidosis, thrichomonias, vaginosis), systemic or local therapies. They incrcase vaginal pH by acting through different mechanisms. The increase of vaginal pH is detrimental for the survival of Doderlein's lactobacillus, but not for the pathogenetic microorganisms whose replication, on the contrary, is favored by the absence of contraction exerted by Doderlein's bacillus. It has been showed that local acidifying substances (lactic acid, lactobacillus and substances recently synthesized like alpha-aminovalerianic acid, policarbophil and carbopol 934) are useful in restoring the biological and chemical characteristics of the vaginal ecosystem.
Multi-view Photometric Stereo with Spatially Varying Isotropic Materials (2013)

We present a method to capture both 3D shape and spatially varying reflectance with a multi-view photometric stereo technique that works for general isotropic materials. Our data capture setup is simple, which consists of only a digital camera and a handheld light source. From a single viewpoint, we use a set of photometric stereo images to identify surface points with the same distance to the camera. We collect this information from multiple viewpoints and combine it with structure-from-motion to obtain a precise reconstruction of the complete 3D shape. The spatially varying isotropic bidirectional reflectance distribution function (BRDF) is captured by simultaneously inferring a set of basis BRDFs and their mixing weights at each surface point. According to our experiments, the captured shapes are accurate to 0.3 millimeters. The captured reflectance has relative root-mean-square error (RMSE) of 9%.
Biomechanical Relationships Between Manual Wheelchair Steering and the Position of the Human Body's Center of Gravity (2020)

The purpose of this investigation was to analyze the impact of differential steering of a wheelchair with a pushrim on changes in the position of the body's center of gravity. The method assumed measuring the wheelchair trajectory and the body's center of gravity and determining the transverse relocation of the measured body's center of gravity in relation to a point on the wheelchair trajectory. Twenty-seven measurement tests which demonstrated various wheelchair trajectories were carried out within the investigation. The trajectories were 10 to 15 m long and involved moving forward (test 2), reversing (test 3), turning left (test 1) and right (test 4). The factor of deviation of the center of gravity of human body from the wheelchair trajectory was determined for selected characteristic turning maneuvers. The measured values ranged from 51 to 192 mm. The impact of the wheelchair trajectory on the position of the body's center of gravity was demonstrated as a result of this investigation. Consequently, a trajectory deviation factor for relocation of the human body weight on one side of the wheelchair has been demonstrated.
Analysis of intact phosphoinositides in biological samples (2006)

It is now apparent that each of the known, naturally occurring polyphosphoinositides, the phosphatidylinositol monophosphates (PtdIns3P, PtdIns4P, PtdIns5P), phosphatidylinositol bisphosphates [PtdIns(3,4)P(2), PtdIns(3,5)P(2), PtdIns(4,5)P(2)], and phosphatidylinositol trisphosphate [PtdIns(3,4,5)P(3)], have distinct roles in regulating many cellular events, including intracellular signaling, migration, and vesicular trafficking. Traditional identification techniques require [(32)P]inorganic phosphate or [(3)H]inositol radiolabeling, acidified lipid extraction, deacylation, and ion-exchange head group separation, which are time-consuming and not suitable for samples in which radiolabeling is impractical, thus greatly restricting the study of these lipids in many physiologically relevant systems. Thus, we have developed a novel, high-efficiency, buffered citrate extraction methodology to minimize acid-induced phosphoinositide degradation, together with a high-sensitivity liquid chromatography-mass spectrometry (LC-MS) protocol using an acetonitrile-chloroform-methanol-water-ethylamine gradient with a microbore silica column that enables the identification and quantification of all phosphoinositides in a sample. The liquid chromatograph is sufficient to resolve PtdInsP(3) and PtdInsP(2) regioisomers; however, the PtdInsP regioisomers require a combination of LC and diagnostic fragmentation to MS(3). Data are presented using this approach for the analysis of phosphoinositides in human platelet and yeast samples.
Activities of Daily Living and the Cardiac Client Who Is Homebound (1995)

Rehabilitation clinical nurse specialist, Visiting Nurse Association of Northern Virginia, Alexandria
Language Support for Design Patterns Using Attribute Extension (1997)

This paper presents a technique based on attribute grammars for formalizing design pattern solutions. The technique allows design pattern applications to be identified in the source code, and supports automatic checking that the pattern is applied correctly. We expect the technique to be particularly useful when specializing frameworks built using design patterns.
Usage History-Based Architectural Scheduling (2009)

Waiting a long time for software applications to load typically elicits an adverse response from the user. This negative response eventually leads to decreased user satisfaction. The waiting time can be reduced by executing the application in improved hardware computing devices and by optimizing the algorithms constituting the application; however, these solutions are costly. An alternative approach is to overlap the execution and waiting times. Although this approach does not reduce the actual waiting time, it can reduce the user's waiting time. This study proposes an approach to decrease the waiting time by scheduling architectural units. The study formulates the dynamic architectural scheduling problem and it provides an overlapping approach to the problem on the basis of the formulation. This approach anticipates subsequent tasks from previous usage history and launches the corresponding components of the anticipated tasks in the task architectures. Evaluation of this approach shows that it effectively schedules applications and reduces waiting time.
3D image correction by Hilbert Huang decomposition (2012)

This paper presented a novel correction for 3D image signals by Hilbert Huang decomposition. Hilbert Huang decomposition is applied for dividing edges of the textures and edges of the objects. Depth map is corrected by regrouping pixels with edges of the objects. The proposed correction outperforms conventional methods especially at the boundaries of the objects.
Coaxial architecture of an optical neural network with a lenslet array (1994)

A theoretical limitation on the neuron numbers (N x N) of a spatial interconnection system based on a lenslet array is analyzed. To improve the limitation, we propose a submatrix coaxial interconnection architecture. Off-axial aberration is decreased, and high light efficiency is achieved. A detailed analysis is given.
Acentriolar mitosis activates a p53-dependent apoptosis pathway in the mouse embryo (2014)

Centrosomes are the microtubule-organizing centers of animal cells that organize interphase microtubules and mitotic spindles. Centrioles are the microtubule-based structures that organize centrosomes, and a defined set of proteins, including spindle assembly defective-4 (SAS4) (CPAP/CENPJ), is required for centriole biogenesis. The biological functions of centrioles and centrosomes vary among animals, and the functions of mammalian centrosomes have not been genetically defined. Here we use a null mutation in mouse Sas4 to define the cellular and developmental functions of mammalian centrioles in vivo. Sas4-null embryos lack centrosomes but survive until midgestation. As expected, Sas4(-/-) mutants lack primary cilia and therefore cannot respond to Hedgehog signals, but other developmental signaling pathways are normal in the mutants. Unlike mutants that lack cilia, Sas4(-/-) embryos show widespread apoptosis associated with global elevated expression of p53. Cell death is rescued in Sas4(-/-) p53(-/-) double-mutant embryos, demonstrating that mammalian centrioles prevent activation of a p53-dependent apoptotic pathway. Expression of p53 is not activated by abnormalities in bipolar spindle organization, chromosome segregation, cell-cycle profile, or DNA damage response, which are normal in Sas4(-/-) mutants. Instead, live imaging shows that the duration of prometaphase is prolonged in the mutants while two acentriolar spindle poles are assembled. Independent experiments show that prolonging spindle assembly is sufficient to trigger p53-dependent apoptosis. We conclude that a short delay in the prometaphase caused by the absence of centrioles activates a previously undescribed p53-dependent cell death pathway in the rapidly dividing cells of the mouse embryo.
Maskless EUV lithography, an alternative to e-beam (2019)

Background: The resolution capability of EUV lithography has reached parity with e-beam, raising the possibility that maskless EUV could supplant e-beam for mask writing and low-volume wafer patterning. Aim: We outline a maskless EUV scanner design with a 13.5-nm operating wavelength and numerical aperture of 0.55. Approach: A microlens array partitions radiation from a commercial laser-produced plasma EUV source into ∼2 million individual beams, which are focused to separate, diffraction-limited focal points on a writing surface, and the surface is raster-scanned across the focal point array as the beams are individually modulated by MEMS microshutters integrated within the microlens array to construct a digitally synthesized raster exposure image. Results: Compared to state-of-the-art mask-projection EUV lithography, the system would have ∼1000 × lower throughput, but its power requirement would also be ∼1000 × lower, the exposure dose would be ∼10 × higher, scan velocity and acceleration would be ∼1000 × lower, and it would have the advantage of maskless operation. In comparison to e-beam mask writers, a maskless EUV scanner could provide higher resolution with at least double the throughput and over 10 × higher dose. Conclusions: Maskless EUV lithography could provide significant cost and performance benefits for both direct-write applications and photomask production for mask-projection lithography.
The Utilization of Phytate Phosphorus by Poultry—A Review (1967)

THE metabolism of phosphorus derived from plant tissues is one of the least understood and most debated subjects in the field of mineral nutrition. A small proportion of the total phosphorus in plants is inorganic phosphates located primarily in the vegetative tissues. Most of the phosphorus is in a variety of organic compounds found primarily in the seed, and phytate phosphorus is the predominant organic form. The amount of phytate phosphorus utilized by animals has economic importance because seeds are the major plant-source ingredients used in feeds. Many scientists currently use the rule that monogastric animals metabolize only one-third of the phosphorus in plant materials. This assumption is based on the report by the Committee on Animal Nutrition, National Academy of Sciences-National Research Council (NAS-NRC) (1960) that approximately 30% of the phosphorus in plant materials in non-phytate and can be considered to be utilized by animals. Many scientists using a …
The American Film Institute (1971)

Journal Article The American Film Institute Get access Richard Thompson Richard Thompson Search for other works by this author on: Oxford Academic Google Scholar Screen, Volume 12, Issue 3, Autumn 1971, Pages 57–96, https://doi.org/10.1093/screen/12.3.57 Published: 01 October 1971
Self-Organizing Traffic Lights (2004)

Steering traffic in cities is a very complex task, since improving efficiency involves the coordination of many actors. Traditional approaches attempt to optimize traffic lights for a particular density and configuration of traffic. The disadvantage of this lies in the fact that traffic densities and configurations change constantly. Traffic seems to be an adaptation problem rather than an optimization problem. We propose a simple and feasible alternative, in which traffic lights self-organize to improve traffic flow. We use a multi-agent simulation to study three self-organizing methods, which are able to outperform traditional rigid and adaptive methods. Using simple rules and no direct communication, traffic lights are able to self-organize and adapt to changing traffic conditions, reducing waiting times, number of stopped cars, and increasing average speeds.
Comparative integromics on FAT1, FAT2, FAT3 and FAT4 (2006)

WNT5A, WNT5B, WNT11, FZD3, FZD6, VANGL1, VANGL2, DVL1, DVL2, DVL3, PRICKLE1, PRICKLE2, ANKRD6, NKD1, NKD2, DAAM1, DAAM2, CELSR1, CELSR2, CELSR3, ROR1 and ROR2 are planar cell polarity (PCP) signaling molecules implicated in the regulation of cellular polarity, convergent extension, and invasion. FAT1, FAT2, FAT3 and FAT4 are Cadherin superfamily members homologous to Drosophila Fat, functioning as a positive regulator of PCP in the Drosophila wing. Complete coding sequence (CDS) for human FAT1 (NM_005245.3) and FAT2 (NM_001447.1) are available, while artificial CDS for human FAT3 (XM_926199 and XM_936538) and partial CDS for FAT4 (NM_024582.2). Here, complete CDS of human FAT3 and FAT4 were determined by using bioinformatics and human intelligence (Humint). FAT3 gene, consisting of 26 exons, encoded a 4557-aa protein with extracellular 33 Cadherin repeats, one Laminin G (LamG) domain and two EGF domains. FAT4 gene encoded a 4924-aa protein with extracellular 34 Cadherin repeats, two LamG domains and three EGF domains. Cytoplasmic VCSVxPxLP and SDYxS motifs were identified as novel motifs conserved among FAT1, FAT2 and FAT3 orthologs. Domain architecture comparison and phylogenetic analysis revealed that FAT1, FAT2 and FAR3 were divergent from FAT4. FAT1-MTNR1A locus at 4q35.2 and FAT3-MTNR1B locus at 11q14.3-q21 were paralogous regions within the human genome. FAT1 mRNA was expressed in embryonic stem (ES) cells, neural tissues, gastric cancer, pancreatic cancer, colorectal cancer, breast cancer, lung cancer and brain tumors. FAT2 mRNA was expressed in infant brain, cerebellum, gastric cancer, pancreatic cancer, ovarian cancer, esophageal cancer, skin squamous cell carcinoma, head and neck cancer. FAT3 mRNA was expressed in ES cells, primitive neuroectoderm, fetal brain, infant brain, adult neural tissues and prostate. FAT4 mRNA was expressed in fetal brain, infant brain, brain tumor and colorectal cancer. FAT family members were revealed to be targets of systems medicine in the fields of oncology and neurology.
Spice Science and Technology (1998)

Offers concise coverage of spices and herbs from basic science to the most recent developments in spice functions and applications. Introduces a new patterning theory of extensive spice use in various types of food preparations.