gebhart/patrepeval huggingface dataset:
Overweight and pregnancy complications. (1988)

The association between increased prepregnancy weight for height and seven pregnancy complications was studied in a multi-racial sample of more than 4100 recent deliveries. Body mass indices were calculated and used to classify women as average weight (90-119 percent of ideal or BMI 19.21-25.60), moderately overweight (120-135 percent ideal or BMI 25.61-28.90), and very overweight (greater than 135 percent ideal or BMI greater than 28.91) prior to pregnancy. Compared to women of average weight for height, very overweight women had a higher risk of diabetes, hypertension, pregnancy-induced hypertension and primary cesarean section delivery. Moderately overweight women were also at higher risk than average for diabetes, pregnancy-induced hypertension and primary cesarean deliveries but the relative risks were of a smaller magnitude than for very overweight women. With women of average prepregnancy body mass as reference, moderately elevated, but not significant relative risks were found for perinatal mortality in the very overweight group, for urinary tract infections in both overweight groups, and a decreased risk for anemia was found in the very overweight group. However, post-hoc power analyses indicated that the number of overweight women in the sample did not allow adequate statistical power to detect these small differences in risk. To overcome limitations associated with low statistical power, the results of three recent studies of these outcomes in very overweight pregnant women were combined and summarized using Mantel-Haenzel techniques. This second, larger analysis suggested that very overweight women are at significantly higher risk for all seven outcomes studied. Summary results for moderately overweight women could not be calculated, since only two of the studies had evaluated moderately overweight women separately. These latter results support other findings that both moderate overweight and very overweight are risk factors during pregnancy, with the highest risk occurring in the heaviest group. Although these results indicate that moderate overweight is a risk factor during pregnancy, additional studies are needed to confirm the impact of being 20-35 percent above ideal weight prior to pregnancy. The results of this analysis also imply that since the baseline incidence of many perinatal complications is low, studies relating overweight and pregnancy complications should include large enough samples of overweight women so that there is adequate statistical power to reliably detect differences in complication rates.
ALPINE - Application Level Programmable Inter-Network Environment (2000)

Future requirements for a broadband multimedia network are likely to be very different from those of today. Three key changes are identified; rapid introduction of new services, dynamic customisation of services by clients, and minimal management overhead. Application layer active networking, perhaps the most pragmatic and immediately realisable active network proposal, is a potential solution to all three. In the management of multiservice networks project, BT and its academic partners are developing key middleware components required to support application layer active networking. 1. INTRODUCTION The characteristics and behaviour of future network traffic will be different from the patterns observed today, generating new requirements for network operators. Voice traffic will become another form of data, most users will be mobile, the amount of traffic generated by machines will exceed that produced by humans, and the data traffic will be dominated by multimedia content. In the mediu...
ChemInform Abstract: The Hydrolysis of Phthalide, Thiophthalide, and Methyl o‐ Methoxybenzoate in Highly Alkaline Media. Curvature in the khyd vs (OH‐ ) Profile. (1995)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: AN INVESTIGATION OF THE GAS‐SOLID INTERFACE REACTION (1974)

Abstract Der Isotopenaustausch zwischen H 2 S und D2 an M032 und MnS bei 420‐500°C wurde kinetisch untersucht.
The relationship between skin stretching/contraction and pathologic scarring: The important role of mechanical forces in keloid generation (2012)

Keloids tend to occur on highly mobile sites with high tension. This study was designed to determine whether body surface areas exposed to large strain during normal activities correlate with areas that show high rates of keloid generation after wounding. Eight adult Japanese volunteers were enrolled to study the skin stretching/contraction rates of nine different body sites. Skin stretching/contraction was measured by marking eight points on each region and measuring the change in location of the marked points after typical movements. The distribution of 1,500 keloids on 483 Japanese patients was mapped. The parietal region and anterior lower leg were associated with the least stretching/contraction, while the suprapubic region had the highest stretching/contraction rate. With regard to keloid distribution, there were 733 on the anterior chest region (48.9%) and 403 on the scapular regions (26.9%). No keloids were reported on the scalp or anterior lower leg. Because these sites are rarely subjected to skin stretching/contraction, it appears that mechanical force is an important trigger that drives keloid generation even in patients who are genetically predisposed to keloids. Thus, mechanotransduction studies are useful for developing clinical approaches that reduce the skin tension around wounds or scars for the prevention and treatment of not only keloids but also hypertrophic scars.
DNA and RNA flow cytometric study in multiple myeloma. Clinical correlations (1991)

Flow cytometric studies of cellular DNA and RNA content using the acridine-orange technique were conducted in 81 patients with multiple myeloma (MM). All patients were treated with the M-2 protocol and clinical response was evaluated according to the criteria of the Chronic Leukemia-Myeloma Task Force. Aneuploid DNA stemlines were found in 38.2% of untreated patients with a median DNA index (DNA-I) of 1.15 in marrow aspirates and 1.22 in biopsy specimens. The median percentage of cells with abnormal DNA content was 31.5 (aspirates) and 35 (biopsy specimens) and a positive correlation with the percentage of bone marrow plasma cells was observed. Significantly higher proliferation (S-phase) was found in marrow biopsy specimens as compared with marrow aspirates. Significantly higher RNA content (RNA index [RNA-I]) was observed in aneuploid versus diploid patients in biopsy material. There was no difference in response to the Memorial Hospital M-2 protocol between diploid and aneuploid patients. In patients with DNA-I greater than 1.15 remission duration was shorter as compared with DNA-I less than or equal to 1.15. Furthermore, no difference in cellular RNA content was noted between responders and nonresponders. This study demonstrates no correlation between cellular RNA content and response, as previously described for patients treated with vincristine, Adriamycin, and dexamethasone (VAD), but DNA aneuploidy appears to be an adverse prognostic factor in MM patients treated with the M-2 protocol. It also demonstrates that prognostic models for MM are not universal but depend on the chemotherapeutic regimen used.
Direct polycondensation of carbon dioxide with xylylene glycols: a new method for the synthesis of polycarbonates (1998)

This communication describes the direct polycondensation of carbon dioxide with p- and m-xylylene glycols using the system trisubstituted phosphine/carbon tetrahalide/base as a condensing agent. The polymerization reaction of carbon dioxide with p-xylylene glycol was carried out in the presence of the condensing agent in N,N-dimethylformamide. The yield was at most 81.0% obtained by using the condensing agent tributylphosphine/carbon tetrabromide/N-cyclohexyl-N′,N′,N″,N″-tetramethylguanidine (CyTMG). The structure of the product was determined by means of 1H NMR, 13C NMR, and IR spectroscopy to be that of a polycarbonate. The molecular weight was estimated to be ca. 1 000–2 000 by 1H NMR analyses.
Compactness Determines the Success of Cube and Octahedron Self-Assembly (2009)

Nature utilizes self-assembly to fabricate structures on length scales ranging from the atomic to the macro scale. Self-assembly has emerged as a paradigm in engineering that enables the highly parallel fabrication of complex, and often three-dimensional, structures from basic building blocks. Although there have been several demonstrations of this self-assembly fabrication process, rules that govern a priori design, yield and defect tolerance remain unknown. In this paper, we have designed the first model experimental system for systematically analyzing the influence of geometry on the self-assembly of 200 and 500 microm cubes and octahedra from tethered, multi-component, two-dimensional (2D) nets. We examined the self-assembly of all eleven 2D nets that can fold into cubes and octahedra, and we observed striking correlations between the compactness of the nets and the success of the assembly. Two measures of compactness were used for the nets: the number of vertex or topological connections and the radius of gyration. The success of the self-assembly process was determined by measuring the yield and classifying the defects. Our observation of increased self-assembly success with decreased radius of gyration and increased topological connectivity resembles theoretical models that describe the role of compactness in protein folding. Because of the differences in size and scale between our system and the protein folding system, we postulate that this hypothesis may be more universal to self-assembling systems in general. Apart from being intellectually intriguing, the findings could enable the assembly of more complicated polyhedral structures (e.g. dodecahedra) by allowing a priori selection of a net that might self-assemble with high yields.
Study on Durability of Embedded Connection for Prestressed Concrete Bridges with Corriugated Steel Webs (2006)

波形鋼板ウェブ橋における埋込み接合部の腐食耐久性を検討するため, (1) シーリング材の有無 (2) 鋼とコンクリートとの付着, および (3) 塗装のコンクリート中への埋込み深さ等をパラメータとした供試体を製作し, 促進腐食実験を行った。実験の結果, シーリング材の有無と塗装の埋込み深さは埋込み接合部の腐食耐久性に大きな影響を及ぼすこと, およびシーリング材を設置することにより埋込み接合部の腐食耐久性は大きく向上すること等が確認された。
Impact of Filter Dispersion Slope in NRZ, CS-RZ, IMDPSK and RZ formats on Ultra High Bit-rate Systems (2002)

The impact of WDM filter dispersion slope on ultra high bit-rate systems is investigated for NRZ, CS-RZ, IMDPSK and RZ modulation formats. It is shown that filter dispersion slope is a limiting factor for future ultra high-speed systems
Industrial Archaeology and its Relevance to the Technical Studies' Teacher (1976)

C hange s bo th in s ociety and i t s a sp i ra t i on s, and i nd us trial structure and r equir e ment s, have re sul te d in a f undamen t al re t hi nk i ng of t h e r ole of th e t e acher of ' c r af t' . Thi s h as cha n ged fr om one of an i mpa r ter of tr a diti on al h and i craft s k ills in wood a n d met a l t o a m uc h wi de r con c ep t o f p r o m oti ng int e rest a n d c o n c er n wi th de s i g n a n d tec h no l ogy and its e ff ects o n t h e so ci e t y in w h ich the young c it izen of t o d a y · fi n ds himself or herself. This widening of aim has demanded a new title for the subject area which better reflects its new role, hence the term design and technology rather than the restriction implied in the word handicraft . The extended field of interest which has come under the purview of the teacher of design and technology has brought with it opportunities for a closer liaison with teachers of the sciences and humanities and the consequent development of integrated study units. It is however essential that such integration is a natural and logical progression and not merely an artificial concoction by those anxious to jump upon any educational bandwaggon that happens to be fashionable at the time. Such a natural and logical progression is provided by industrial archaeology. At the same time this discipline can play an effective r o le in ex p laining to the maturing mind the basis of Britain's present s o ci o - e c o n o mic struc t u r e a n d tec hn ical d ev el o pment.
High-resolution single-shot spectral monitoring of hard x-ray free-electron laser radiation (2015)

We have developed an on-line spectrometer for hard x-ray free-electron laser (XFEL) radiation based on a nanostructured diamond diffraction grating and a bent crystal analyzer. Our method provides high spectral resolution, interferes negligibly with the XFEL beam, and can withstand the intense hard x-ray pulses at high repetition rates of >100 Hz. The spectrometer is capable of providing shot-to-shot spectral information for the normalization of data obtained in scientific experiments and optimization of the accelerator operation parameters. We have demonstrated these capabilities of the setup at the Linac Coherent Light Source, in self-amplified spontaneous emission mode at full energy of >1 mJ with a 120 Hz repetition rate, obtaining a resolving power of Ε/δΕ > 3 × 10<sup>4</sup>. In conclusion, the device was also used to monitor the effects of pulse duration down to 8 fs by analysis of the spectral spike width.
Extending TLSforTrustDelegation inHomeNetworks (2006)

Thepopularity ofhomenetworks isappealing to undertaken inthefield ofhomenetwork security. Considering anincreasing needforsecurity. Emerging social concepts suchas thepopularity ofhomenetworks andthat scarce expertise is telecommutation brought a newkindofsensitive dataand security, itisreasonable toexpect that firms withappropriate consequently newsecurity threats tothehomeenvironment. expertise cantaketheresponsibilities ofguarding precious Besides, low-capacity devices inthehomedomainmayneeda homeresources andinformation onbehalf oftheownerorthat central entity totaketheresponsibility ofsecurity enforcement. dedicated entities enforce security on behaveofthehome Inthis case, whichlevel oftrust should beimparted tothis security gateway isproblematic andevenmorecomplex ishowto network terminals. Amain issue inhomesecurlity protocol managethis trust foranoutside client. Wehaveextended TLS architectures likegivenin(10)ishowmulti-vendor entities protocol todelegate trust establishment between ahomenetworkwilltrusteachother?Further, how toavoida complete server andanexternal client toaresidential (security) gateway.exposure toathird-party gateway, ifnecessary? We have Inorder tobesurethat ourarchitecture doesn't introduce any proposed minorchanges instandard TLSprotocol toadapt to security flaw, weformally validated itusing automatic protocoltheaboveneedsandvalidated itwithanautomated security analyzer AVISPA. analyzer AVISPA(5) (7).
A comprehensive Monte Carlo calculation of dopant contrast in secondary-electron imaging (2008)

Two-dimensional dopant mapping using secondary electrons in a scanning electron microscope is a useful and rapid technique for studying dopant distributions with high spatial resolution in semiconductor materials and devices. However, it has not yet found widespread application because the quantification of dopant concentrations currently lacks a firm theoretical model. This paper addresses the issue by means of Monte Carlo modelling. We demonstrate that by taking account of the electron affinity in Monte Carlo simulations to calculate the secondary-electron emission from doped silicon the dopant contrast can be explained. This paper also provides a firm theoretical model about the existence of surface effects in dopant contrast imaging.
Interleukin-6 (IL-6) inhibits thyroid function in the presence of soluble IL-6 receptor in cultured human thyroid follicles. (1996)

Interleukin-6 (IL-6), a pleiotropic cytokine, is postulated to be involved in the pathogenesis of sick euthyroid syndrome, although the direct in vitro effects of IL-6 on human thyroid function are controversial. Because IL-6 signal can be transduced when the complex of IL-6 and soluble IL-6 receptor (sIL-6R) binds to gp 130, an IL-6 signal transducer, we studied the effects of IL-6 and sIL-6R on thyroid function, using human thyroid follicles obtained from patients with Graves' disease. IL-6 alone had no inhibitory effect on TSH-induced thyroid function (125I incorporation and organic 125I release), even at supraphysiological concentrations. However, in the presence of physiological concentrations of sIL-6R (100 ng/ml), IL-6 inhibited thyroid function dose dependently and completely, accompanied with the decreased ratio of 125I-T3/125I-T4 not only in the thyroid follicles but also in the culture medium. Thyroid follicles did not secrete sIL-6R but produced IL-6 constitutively. Consistent with these findings, sIL-6R inhibited thyroid function slightly at high concentrations. Furthermore, RT-PCR analyses revealed that human thyroid follicles expressed the messenger RNAs for IL-6 and gp130 but scarcely messenger RNA for IL-6R. These in vitro findings suggest that IL-6 alone hardly affects thyroid function in thyroid follicles in which IL-6R gene is scarcely expressed. However, because sIL-6R is present abundantly in serum, IL-6 in vivo would be capable of inhibiting the synthesis and release of T4 and, to a greater extent, T3 from the thyroid gland. These in vitro findings are at least partly related to the development of sick euthyroid syndrome.
Hazards from High Intensity Lamps and Arcs (1970)

The principal occupational health problem generally associated with high intensity arc lamps results from exposure of the eye and skin to ultraviolet radiation. Occasionally, the chorioretinal burns are of concern. The eye is generally more susceptible than the skin to injury from high intensity optical radiation sources whether ultraviolet, visible or infrared. Recent developments in technology have shown that some high intensity optical radiation sources which have output parameters greatly different from those encountered in the natural environment present a serious chorioretinal burn hazard.
Isolation of immunoglobulins from colostrum (2004)

The immunoglobulins (Igs) of bovine colostrum provide a major antimicrobial protection against microbial infections and confer a passive immunity to the newborn calf until its own immune system has matured. Probably due to this unique function Igs represent the major protein fraction of colostrum accounting for 70-80% of its total protein content. In the first milking after parturition the concentration of Igs may range from 20 to 200 grams per litre being on an average 60 g/l. The Ig concentration drops rapidly thereafter and remains at the level of 0.5-1.0 g/l during the main lactation period. Bovine colostrum and milk contain three major classes of Igs: IgG, IgM and IgA. The basic structure of all Igs is similar to IgG but the physico-chemical characteristics and biological functions differ depending on the Ig class. The molecular weight of different Ig classes varies between 160 and 900 kDa. In bovine colostrum and milk, IgG represents the major Ig class followed by IgM and IgA, respectively. Bovine Igs are formed as a response to antigenic or immunogenic material present in the cow's feeds or immediate environment. Ordinary colostrum contains, therefore, a wide spectrum of natural antibodies against a great variety of microorganisms, including potential pathogens. Using bovine colostrum as a source of antibody preparations for health promotion in farm animals and even by humans has been an interesting research subject for many decades. One of the main challenges of this research has been the enrichment or isolation of active Igs from colostrum due to its complex composition. Also, the Igs are relatively heat sensitive and will not survive heat-sterilization processes. These technological problems have been overcome by recent advances in bioseparation and chromatography techniques which have made it possible to fractionate and isolate Igs from colostral and cheese whey on a large scale. Colostral Ig supplements have been developed for farm animals to protect against diarrhea and since recently colostrums-based products are marketed also for human use as dietary supplements. Also, renewed interest has been focused on the possibilities of exploiting bovine colostral Igs for the prevention and treatment of various microbial human gastrointestinal diseases. The concentration of specific Igs (antibodies) against pathogenic microorganisms can be raised in colostrum and milk by immunizing cows with a vaccine made of these microbes or their antigens. In clinical trials such immune milk preparations have proven effective against many human microbial diseases. This article reviews the recent progress made in isolation techniques of bovine Igs and highlights the use of specific Igs for promotion of human health.
Torsional Instability of the Lumbar Spine (1999)

This study was to test the hypothesis that in disc degeneration there is increased intervertebral rotation when the spine is subjected to a torsional stress. Twenty-five patients with chronic low back pain without sciatica were examined in all five lumbar disc levels by both a diagnostic and a functional CT scan, the latter performed with maximal rotation of the lumbar spine. The results showed that the normally small rotation between the lumbar vertebrae was increased in the presence of disc bulges, and particularly in disc herniations.
Reexamination of the 1H and 13C NMR spectral assignments of thiostrepton. (1989)

The use of 2D NMR techniques on unlabeled and biosynthetically multiple 13C-labeled samples enabled us to refine the 1H and 13C NMR spectral assignments for thiostrepton.
Fatal attraction: chemokines and type 1 diabetes (2002)

Nonstandard abbreviations used:CC chemokine receptor (CCR); CXC chemokine receptor (CXCR); nonobese diabetic (NOD); monocyte chemoattractant protein (MCP); macrophage inflammatory protein (MIP); regulated on activation, normal T cell expressed and secreted
Microwave Limiters (1999)

Abstract The sections in this article are Solid‐State Limiters Gaseous Limiters Ferrite Limiters Other Limiter Technologies Future Activities
SimuLTE-MEC: Extending SimuLTE for Multi-Access Edge Computing (2018)

Multi-access Edge Computing (MEC) is a novel paradigm to enrich current 4G and future 5G cellular networks by placing cloud-computing-based capabilities at the edge of the network. This will allow operators and service providers to endow the cellular network with enriched services. In this paper we describe the modeling and development of a MEC extension for the SimuLTE framework.
[Stem cell therapy for intractable skin diseases]. (2011)

Previous studies have shown that bone marrow provides fibroblastic-like cells in the dermis and keratinocytes in the epithelia. Subsequent studies by us and other groups have demonstrated that both embryonic and postnatal transplantation of bone marrow cells in model mice of epidermolysis bullosa (EB), a heritable blistering skin disease due to genetic mutation of cutaneous basement membrane components, promote skin wound healing and correct the intrinsic basement membrane defect. We also reported that the source of the epithelial progenitors in mouse bone marrow was the nonhematopoietic, platelet-derived growth factor receptoralpha (PDGFRalpha)-positive bone marrow mesenchymal stem cell (MSC) population. In this review, recent progress as well as future perspectives of bone marrow MSC therapy for EB will be summarized.
Endotoxin Stimulates Interleukin-6 Production in Intestinal Epithelial Cells (1994)

Endotoxin and PGE2 stimulate IL-6 production in IEC-6 cells and interact synergistically. The endotoxin-stimulated IL-6 release may be regulated at the transcriptional level.