gebhart/patrepeval huggingface dataset:
Communication during downsizing of a telecommunications company (2003)

Reports the emergency stopgap measures undertaken by industry giant Tele Link to counteract downward market trends and the ensuing problems caused by its Efficiency Program not being managed effectively, resulting in lingering and negative impact on surviving employees’ behaviors and attitudes, demonstrated by decreases in productivity, motivation, emotional health, job satisfaction, and confidence in management, as well as increases in absenteeism. Also reports Tele Link was unprepared to handle the inevitable pre‐announcement rumor mill and was forced to present cutbacks prematurely, lengthening the period of time from announcement to implementation and fueling anxiety at the time. While Tele Link’s handling of the Efficiency Program is well rated it did concentrate, almost entirely, on the “during” phase, with no formal plans to help survivors mourn or adjust to new circumstances. Emphasizes that the power of informal communication, in this case the “rumor mill”, should not be underestimated, and management should not overestimate their own ability to control it.
Fast finite-difference time-domain modeling for marine-subsurface electromagnetic problems (2007)

Abstract In the low-frequency limit, the displacement currents in the Maxwell equations can be neglected. However, for numerical simulations, a small displacement current should be present to achieve numerical stability. This requirement leads to a large range of propagation velocities with high velocities for the high frequencies and low velocities for the low frequencies. As a consequence, the number of time steps may become large. I show that it is possible to transform mathematically the original physical problem to one that has propagation velocities with less frequency dependence. Hence, the number of time steps necessary for a signal to travel a certain distance with the lowest velocity is significantly reduced. A typical example shows a reduction in computational time by a factor of 40. A comparison of the solutions from plane-layered modeling in the frequency and wavenumber domain and the proposed method shows good agreement between the two. The proposed method can also be used for other systems of diffusive equations.
Inorganic halogen ligands in quantum dots: I−, Br−, Cl− and film fabrication through electrophoretic deposition (2013)

Halogen ions (I(-), Br(-), Cl(-)) were added into a colloidal solution of CdSe and PbS quantum dots (QDs) to form QDs capped with these inorganic ligands. Halogen ions attached to QDs through electrostatic interactions and the varying coordination strength between the inorganic ligands and QDs led to different degrees of redispersion and stabilization in polar solvents. Moreover, we successfully conducted electrophoretic deposition (EPD) of QDs capped with inorganic ligands. Negatively charged QDs were adsorbed onto a positively charged TiO2 anode. The assembled QDs films were used in photovoltaic devices and offered better efficiency than QDs capped with organic ligands. This work demonstrates that halogen ions are indeed promising ligands to improve the stability of QDs with inorganic ligands and the EPD method shows prospects in assembling QDs films for practical applications.
White Paper: Developing Antimicrobial Drugs for Resistant Pathogens, Narrow-Spectrum Indications, and Unmet Needs (2017)

Despite progress in antimicrobial drug development, a critical need persists for new, feasible pathways to develop antibacterial agents to treat people infected with drug-resistant bacteria. Infections due to resistant gram-negative bacilli continue to cause unacceptable morbidity and mortality rates. Antibacterial agents have been historically studied in noninferiority clinical trials that focus on a single site of infection (eg, complicated urinary tract infections, intra-abdominal infections), yet these designs may not be optimal, and often are not feasible, for study of infections caused by drug-resistant bacteria. Over the past several years, multiple stakeholders have worked to develop consensus regarding paths forward with a goal of facilitating timely conduct of antimicrobial development. Here we advocate for a novel and pragmatic approach and, toward this end, present feasible trial designs for antibacterial agents that could enable conduct of narrow-spectrum, organism-specific clinical trials and ultimately approval of critically needed new antibacterial agents.
HYPERPROLACTINAEMIA AND LONG‐TERM LACTATIONAL AMENORRHOEA (1980)

Clinical details of lactational and menstrual history post-partum have been correlated with measurements of serum prolactin, luteinizing hormone, follicle stimulating hormone, oestradiol and progesterone in Transkei women in order to gain further insight into the role of prolactin in the maintenance of post-partum lactational amenorrhoea. Of seventy-four breast-feeding mothers studied, sixty-six had elevated serum levels of prolactin. Forty-four women were amenorrhoeic with minimal or absent endocrine evidence of ovarian activity. Of the twenty-seven lactating women who reported menstruation, twelve had high levels of prolactin and no apparent ovarian activity, eleven had lower prolactin levels and increased oestradiol levels suggesting ovarian follicular development, while only four women had increased progesterone levels indicating definite luteal activity. Three lactating women were pregnant. The results support previous reports that lactational amenorrhoea is associated with hyperprolactinaemia and a possible sequence of endocrine events resulting in the return of post-partum fertility is proposed.
Serologic Evidence of Human Monocytic and Granulocytic Ehrlichiosis in Israel (2000)

DOAJ is a unique and extensive index of diverse open access journals from around the world, driven by a growing community, committed to ensuring quality content is freely available online for everyone.
Saturable binding sites for vesicular stomatitis virus on the surface of Vero cells (1982)

The binding of vesicular stomatitis virus (VSV) to Vero monkey cells was studied by using virus metabolically labeled with [35S]methionine. Under conditions where viral uptake did not occur (4 degrees C), apparent binding equilibrium was achieved within 12 h at a level representing 12% of the input virus. Two distinct forms of virus-cell interaction were found. At low concentrations of VSV, corresponding to multiplicities used for tissue culture studies, saturable binding was the major form of interaction. Saturation was complete at approximately 4,000 VSV virions per cell. At higher virus concentrations, nonsaturable binding prevailed. Trypsin treatment of Vero cells did not decrease the binding of VSV to the saturable binding sites. Internalization of VSV at 37 degrees C also displayed a saturable component which was directly comparable to that observed for binding. VSV binding to high-affinity, saturable sites on the plasma membrane may represent a receptor-mediated route of viral uptake.
A Model System for the Study of Luteinizing Hormone (LH) Secretion: Lack of Effect of Fetal Calf Serum on Gonadotropin-Releasing Hormone Stimulated LH Release (1982)

Continuous perifusion of dispersed anterior pituitary cells recently has been applied to the study of LH secretion. We undertook a series of experiments to determine whether or not fetal calf serum(FCS) is a necessary or beneficial addition to medium perifusing cells in culture up to 43.5 hr. Male Sprague-Dawley rats provided pituitaries for two perifusion systems (columns) set up in parallel. The cells in one column were perifused on both Day 1 (first 19.5 hr) and Day 2 (subsequent 24 hr) with Medium 199, while the cells in the other column were perifused with Medium 199 on Day 1 and with Medium 199 with 2% FCS for the initial 18 hr on Day 2. On Days 1 and 2 cells in both columns were challenged with five doses of GnRH (1-100 nM) given as 1.5-min pulses in a random order. After 4-hr of perifusion, basal release of LH decreased gradually with time in a manner that fit a least-squares derived second-order polynomial function. Mean basal LH release (ng/ml/107 cells ± SEM) on Days 1 (9822 ± 2450) and 2 (7710 ± 2100) was no different (P = 0.1). Mean GnRH-stimulated LH release on Day 1 (1063 ± 144.3) was higher than on Day 2 (746 ± 143.7) (P = 0.036). GnRH-stimulated LH release on Day 2 was the same for the columns with (805.9 ± 41.9) and without (653.2 ± 190.8) FCS (P = 0.9); furthermore, the slopes of the dose-response curves were identical (P = 0.9). Thus, our results showed that, using continuously perifused dispersed rat anterior pituitary cells for up to 43.5 hr: (1) basal LH release does not change significantly; (2) GnRH-stimulated LH release becomes less with time but dose-response characteristics remain constant; and (3) preincubation with FCS appears unnecessary to maintain responsivity of cells. Furthermore, we propose that the quantitative methods used to analyze our data may prove useful to other investigators employing similar perifusion techniques, thus allowing comparison of results from various laboratories.
Fault-tolerant 3D clock network (2011)

Clock tree synthesis is one of the most important and challenging problems in 3D ICs. The clock signals have to be delivered by through-silicon vias (TSVs) to different tiers with minimum skew and latency. While there are a few related works in literature, none of them considers the reliability of TSVs. Accordingly, the failure of any TSV in the clock tree yields a bad chip. The naive solution using double-TSV can alleviate the problem. But the significant area overhead renders it less practical for large designs. In this paper, we propose a novel TSV fault-tolerant unit (TFU) that can provide tolerance against TSV failures in a 3D clock network. It makes use of the existing 2D redundant trees designed for pre-bond testing, and thus has minimum area overhead. Compared to the double TSV technique, the 3D clock network constructed by our TFUs can achieve 61% area reduction with 3.9% yield rate improvement on an industrial case. To the best of the authors' knowledge, this is the first practical work in literature that considers the fault tolerance of a 3D clock network.
Effects of genetic hypertension on diabetic nephropathy in the rat ??? functional and structural characteristics (1988)

Streptozotocin (STZ) diabetes was induced in spontaneously hypertensive (SHR) and normotensive Wistar-Kyoto (WKY) rats. Body weight, blood pressure, renal function, glycaemic control and proteinuria were assessed monthly for 32 weeks. At 32 weeks, the animals were killed and glomerular basement membrane (GBM) thickness and fractional mesangial volume were measured. There was no significant difference in renal function between diabetic SHR and diabetic WKY. Diabetic SHR showed an earlier and larger rise in total proteinuria and urinary albumin excretion than diabetic WKY. Urinary albumin excretion was increased more than tenfold in diabetic SHR compared to diabetic WKY after 32 weeks of diabetes. GBM thickness was significantly increased in diabetic SHR compared with diabetic WKY. Both diabetic WKY and diabetic SHR showed mesangial expansion when compared to their nondiabetic counterparts. On the other hand, both hypertensive models showed increased glomerular volume, which was not influenced by the presence of diabetes. The diabetic SHR model has features of accelerated nephropathy, as evidenced by increased albuminuria and GBM thickness. This suggests that pre-existing hypertension may play an important role in the progression of diabetic renal disease.
SCOMIL: uma ferramenta livre para criação de conteúdo multimídia baseada nos padrões SCORM e SMIL (2007)

Resumo: Este artigo apresenta o SCOMIL, um prototipo para construcao de conteudo multimidia na area de Educacao a Distância. O prototipo utiliza os padroes SCORM e SMIL com o objetivo de oferecer uma solucao de baixo custo e facil implantacao para a geracao e o gerenciamento de conteudo multimidia. Abstract: Este artigo apresenta o SCOMIL, um prototipo para construcao de conteudo multimidia na area de Educacao a Distância. O prototipo utiliza os padroes SCORM e SMIL com o objetivo de oferecer uma solucao de baixo custo e facil implantacao para a geracao e o gerenciamento de conteudo multimidia.
Medical treatment overview (2011)

Accumulating data suggest a series of existing medications may be useful in ASD and large randomized clinical trials are necessary to evaluate safety and efficacy of both pharmaceuticals and alternative treatments.
Density functional simulations of noble-gas impurities in diamond (2009)

Noble-gas species are important impurities in the geological analysis of natural diamond and are also used in ion implantation on the basis of chemical inertness. We present the results of density functional simulations of noble-gas atoms in diamond. We show that interstitial species are relatively mobile under geological conditions but require annealing above $\ensuremath{\sim}700\text{ }\text{K}$ for laboratory-based experiments. In addition, with the exception of interstitial helium and neon, the noble-gas atoms are able to react chemically with the diamond due to the compact diamond lattice. This is of particular significance in terms of ion implanted material where noble-gas species trapped in lattice vacancies are electrically active and stable to high temperatures.
Multilayer Coated Echelle Gratings for Soft X-rays (1994)

Recently there have been many experimental and theoretical studies of diffraction gratings coated with short-period multilayers to enhance their reflectivity in the extreme ultraviolet and x-ray regions. Much of this work has been focussed on lamellar gratings, but there is also considerable interest in multilayer coated blazed gratings. Until now, these blazed gratings have been made by traditional ruling. In an interferometrically controlled ruling engine this leads to very accurate groove placement, but the quality of the groove surfaces may be poor because the grooves are burnished into a soft material such as gold. This leads to low multilayer reflectivity because the substrate roughness (in this case the groove surface) is an important factor in determining its performance. In addition the gratings can be used only in low orders, since operation in higher orders requires excellent groove profile.
Studies of the pathogenesis of arteriosclerosis induced in rats by intrarenal injection of a carcinogen, nickel subsulfide. (1984)

Widespread arteriosclerotic lesions were detected by histological examinations of rats killed at seven or nine weeks after an intrarenal (ir) injection of nickel subsulfide (Ni3S2, 5 mg per rat). Arteriosclerotic plaques were readily visualized by administering hematoporphyrin derivative (HPD) iv to rats at 24 hours before sacrifice. At necropsy, the major arteries were inspected under ultraviolet light, revealing patches of intense HPD-fluorescence in the arterial endothelium of Ni3S2-treated rats, but not in control rats. Consistent with previous reports, the Ni3S2-treated rats developed pronounced erythrocytosis; blood hematocrit values averaged 70 +/- 4 percent at seven weeks after ir injection of Ni3S2 (P less than 0.001 vs corresponding value of 49 +/- 2 percent in vehicle controls). At seven weeks, blood platelet counts averaged 17 percent lower and serum glucose concentrations averaged 23 percent lower in Ni3S2-treated rats than in controls; serum lipids, lipoproteins, non-protein nitrogen constituents, electrolytes, proteins, and enzymes were not significantly affected. Body weights and systolic blood pressures of rats at two, four, and six weeks after ir injection of Ni3S2 did not differ from corresponding values in controls. Addition of egg yolk to the diet caused mild hypercholesterolemia, but it did not enhance the incidence or severity of arterial lesions in Ni3S2-treated rats. These findings exclude hypertension and hyperlipidemia as pathogenic factors in Ni3S2-induced arteriosclerosis.
Advanced intermediate temperature sodium–nickel chloride batteries with ultra-high energy density (2016)

Sodium-metal halide batteries have been considered as one of the more attractive technologies for stationary electrical energy storage, however, they are not used for broader applications despite their relatively well-known redox system. One of the roadblocks hindering market penetration is the high-operating temperature. Here we demonstrate that planar sodium-nickel chloride batteries can be operated at an intermediate temperature of 190 °C with ultra-high energy density. A specific energy density of 350 Wh kg(-1), higher than that of conventional tubular sodium-nickel chloride batteries (280 °C), is obtained for planar sodium-nickel chloride batteries operated at 190 °C over a long-term cell test (1,000 cycles), and it attributed to the slower particle growth of the cathode materials at the lower operating temperature. Results reported here demonstrate that planar sodium-nickel chloride batteries operated at an intermediate temperature could greatly benefit this traditional energy storage technology by improving battery energy density, cycle life and reducing material costs.
Connecting performance to social structure and pedagogy as a pathway to scaling learning analytics in MOOCs: an exploratory study (2016)

Abstract This exploratory study focuses on the design and evaluation of teaching analytics that relate social learning structure with performance measures in a massive open online course (MOOC) prototype environment. Using reflexive analysis of online learning trace data and qualitative performance measures we present an exploratory empirical study that: (a) rigorously evaluates a novel, multi‐dimensional performance construct; (b) describes differences in small group dynamics and structure; and (c) draws a connection between learning performance and group structure. Performance is operationalized using a combination of knowledge construction measurement from discussion boards, rigorous analysis of student work products and several indicators of small group identity in the course examined. Interview and observational data are used to develop an approach for deriving and validating a model of the social structure of students in the course using traces of interaction data. The connection between performance and structure is developed at the small group unit of analysis. Implications for MOOC design, scaling MOOC analytics and a vision for developing social sensors in MOOC environments are presented in the discussion and conclusion.
Methoden Der Organischen Chemie (Houben-Weyl). Fourth Edition. Edited by Eugen Müller (1959)

Methoden Der Organischen Chemie (Houben-Weyl). Fourth Edition. Edited by Eugen Müller Get access J B Stenlake J B Stenlake Search for other works by this author on: Oxford Academic Google Scholar Journal of Pharmacy and Pharmacology, Volume 11, Issue 1, September 1959, Page 63, https://doi.org/10.1111/j.2042-7158.1959.tb12526.x Published: 12 April 2011
Assessment of mitochondrial impairment in traumatic brain injury using high-resolution proton magnetic resonance spectroscopy (2008)

Using (1)H-MR spectroscopy, it is possible to detect the posttraumatic neurochemical damage of the injured brain when conventional neuroimaging techniques reveal no abnormality. Reduction of NAA levels is a dynamic process, evolving over time, decreasing and remaining low throughout the involved tissue in patients with poor outcomes. Recovery of NAA levels in patients with favorable outcomes suggests marginal mitochondrial impairment and possible resynthesis from vital neurons.
Better than 1 Hop Lookup Performance with Proactive Caching (2004)

High lookup latencies prohibit peer-to-peer overlays from being used in many performance intensive applications, even though they provide self-organization, scalability, and failure resilience. In this paper, we show that lookup performance of structured DHTs can be improved to any desirable constant, even under 1 hop, by controlled proac-tive replication. By exploiting the popularity distribution of objects, we can minimize the number of replicas and re-duce the storage and bandwidth cost of replication. This enables structured DHTs to efficiently support a wide va-riety of latency sensitive applications. We describe three different applications, namely DNS, web access, and con-tent distribution, and show how they can derive significant performance gains by using DHTs. 1
Motility of Live Cancer Cells Quantified by Fourier Phase Microscopy (2005)

Using Fourier phase microscopy, the motility of epithelial cancer cells has been quantified. The mean squared displacement analysis suggest that the cell motion is superdiffusive for cells at various stages of their life cycle.
Quantitative sensory examination of epidural anaesthesia and analgesia in man: combination of morphine and bupivacaine (1994)

The effect of epidural administration of a combination of low-dose morphine (2 mg) and bupivacaine (25 mg) on somatosensory and motor functions was examined in 13 healthy volunteers. The study design was a double-blind 4-way cross-over in which combined treatment was compared with either drug used alone or placebo. Every 2nd hour for 10 h effects on nociceptive and non-nociceptive somatosensory functions were quantified with 12 psychophysical measures. In addition knee extension strength, reaction time and skin temperature were examined. Epidural bupivacaine had hypoalgesic effect in all nociceptive tests, whereas epidural morphine only demonstrated hypoalgesic properties in nociceptive test with prolonged stimuli. In comparison with bupivacaine alone the combination treatment had a lesser peak effect but a more prolonged hypoalgesic action. In comparison with morphine alone the combination treatment induced a faster onset and demonstrated a modest increase in hypoalgesic effect in a subset of the test, even beyond the duration of bupivacaine when administered alone. Motor function was not attenuated by any of the treatments. Mechanisms of interaction between morphine and bupivacaine as well as their possible clinical implications are discussed.
Thallium in organic synthesis. II. Acylation, aroylation, and tosylation of phenols and carboxylic acids (1968)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThallium in organic synthesis. II. Acylation, aroylation, and tosylation of phenols and carboxylic acidsEdward C. Taylor, G. W. McLay, and Alexander McKillopCite this: J. Am. Chem. Soc. 1968, 90, 9, 2422–2423Publication Date (Print):April 1, 1968Publication History Published online1 May 2002Published inissue 1 April 1968https://doi.org/10.1021/ja01011a040Request reuse permissionsArticle Views531Altmetric-Citations44LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (256 KB) Get e-Alertsclose Get e-Alerts
An Isopyoverdin from Pseudomonas putida CFML 90-44 (2001)

From Pseudomonas putida CFML 90-44 an isopyoverdin was isolated. Its structure could be elucidated by chemical degradation and spectroscopic data.