gebhart/patrepeval huggingface dataset:
Large MIMO Systems: A Low-Complexity Detector at High Spectral Efficiencies (2008)

We consider large MIMO systems, where by 'large' we mean number of transmit and receive antennas of the order of tens to hundreds. Such large MIMO systems will be of immense interest because of the very high spectral efficiencies possible in such systems. We present a low-complexity detector which achieves uncoded near-exponential diversity performance for hundreds of antennas in V-BLAST (i.e., achieves near SISO AWGN performance in a large MIMO fading environment) with an average per-bit complexity of just 0(N <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">t</sub> N <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">r</sub> ), where N <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">t</sub> and N <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">r</sub> denote the number of transmit and receive antennas, respectively. With an outer turbo code, the proposed detector achieves good coded bit error performance as well. For example, in a 600 transmit and 600 receive antennas V-BLAST system with a high spectral efficiency of 200 bps/Hz (using BPSK and rate-1/3 turbo code), our simulation results show that the proposed detector performs close to within about 4.6 dB of the theoretical capacity. We also adopt the proposed detector for the low-complexity decoding of high-rate non-orthogonal space- time block codes (STBC) from division algebras (DA). We have decoded the 16x16 full-rate STBC from DA using the proposed detector and show that it performs close to within about 5.5 dB of the capacity using 4-QAM and rate-3/4 turbo code at a spectral efficiency of 24 bps/Hz. The practical feasibility of the proposed high-performance low-complexity detector could trigger wide interest in the implementation of large MIMO systems.
A Block to Human Immunodeficiency Virus Type 1 Assembly in Murine Cells (2000)

Human immunodeficiency virus type 1 (HIV-1) does not replicate in murine cells. We investigated the basis of this block by infecting a murine NIH 3T3 reporter cell line that stably expressed human CD4, CCR5, and cyclin T1 and contained a transactivatable HIV-1 long terminal repeat (LTR)-green fluorescent protein (GFP) cassette. Although the virus entered efficiently, formed provirus, and was expressed at a level close to that in a highly permissive human cell line, the murine cells did not support M-tropic HIV-1 replication. To determine why the virus failed to replicate, the efficiency of each postentry step in the virus replication cycle was analyzed using vesicular stomatitis virus G pseudotypes. The murine cells supported reverse transcription and integration at levels comparable to those in the human osteosarcoma-derived cell line GHOST.R5, and human cyclin T1 restored provirus expression, consistent with earlier findings of others. The infected murine cells contained nearly as much virion protein as did the human cells but released less than 1/500 the amount of p24(gag) into the culture medium. A small amount of p24(gag) was released and was in the form of fully infectious virus. Electron microscopy suggested that aberrantly assembled virion protein had accumulated in cytoplasmic vesicular structures. Virions assembling at the cell membrane were observed but were rare. The entry of M-tropic JR.FL-pseudotyped reporter virus was moderately reduced in the murine cells, suggesting a minor reduction in coreceptor function. A small reduction in the abundance of full-length viral mRNA transcripts was also noted; however, the major block was at virion assembly. This could have been due to a failure of Gag to target to the cell membrane. This block must be overcome before a murine model for HIV-1 replication can be developed.
Ganglioside inhibition of glutamate-mediated protein kinase C translocation in primary cultures of cerebellar neurons. (1987)

In primary cultures of cerebellar granule cells, protein kinase C (PKC) translocation and activation can be triggered by the stimulation of excitatory amino acid neurotransmitter receptors. Glutamate evokes a dose-related translocation of 4-beta-[3H]phorbol 12,13-dibutyrate ([3H]-P(BtO)2) binding sites from the cytosol to the neuronal membrane and stimulates the incorporation of 32P into a number of membrane proteins, particularly protein bands in the range of 80, 50, and 40 kDa. The glutamate-evoked PKC translocation is Mg2+ sensitive, is prevented by 2-amino-5-phosphonovalerate and phencyclidine, is not inhibited by nitrendipine (a voltage-dependent Ca2+-channel blocker) but is abolished by the removal of Ca2+ from the incubation medium, suggesting that glutamate-mediated Ca2+ influx is operative in the redistribution of PKC. Exposure of granule cells to the gangliosides trisialosylgangliotetraglycosylceramide (GT1b) or monosialosylgangliotetraglycosylceramide (GM1) inhibits the translocation and activation of PKC evoked by glutamate. These glycosphingolipids fail to interfere with glutamate binding to its high-affinity recognition site or with the [3H]P(BtO)2 binding, nor do they affect the Ca2+ influx. These gangliosides may prevent PKC translocation by interfering with the PKC binding to the neuronal membrane phosphatidylserine.
POS-1 and GLD-1 repress<i>glp-1</i>translation through a conserved binding-site cluster (2012)

RNA-binding proteins (RBPs) coordinate cell fate specification and differentiation in a variety of systems. RNA regulation is critical during oocyte development and early embryogenesis, in which RBPs control expression from maternal mRNAs encoding key cell fate determinants. The Caenorhabditis elegans Notch homologue glp-1 coordinates germline progenitor cell proliferation and anterior fate specification in embryos. A network of sequence-specific RBPs is required to pattern GLP-1 translation. Here, we map the cis-regulatory elements that guide glp-1 regulation by the CCCH-type tandem zinc finger protein POS-1 and the STAR-domain protein GLD-1. Our results demonstrate that both proteins recognize the glp-1 3' untranslated region (UTR) through adjacent, overlapping binding sites and that POS-1 binding excludes GLD-1 binding. Both factors are required to repress glp-1 translation in the embryo, suggesting that they function in parallel regulatory pathways. It is intriguing that two equivalent POS-1-binding sites are present in the glp-1 3' UTR, but only one, which overlaps with a translational derepression element, is functional in vivo. We propose that POS-1 regulates glp-1 mRNA translation by blocking access of other RBPs to a key regulatory sequence.
Fuzzy Approximate Model for Distributed Thermal Solar Collectors Control (2014)

This paper deals with the problem of controlling concentrated solar collectors where the objective\nconsists of making the outlet temperature of the collector tracking a desired reference. The performance of the\nnovel approximate model based on fuzzy theory, which has been introduced by the authors in [1], is evaluated\ncomparing to other methods in the literature. The proposed approximation is a low order state representation\nderived from the physical distributed model. It reproduces the temperature transfer dynamics through the collectors\naccurately and allows the simplification of the control design. Simulation results show interesting performance of\nthe proposed controller.
Addition of a minimally invasive medial orbital approach in the endoscopic management of advanced sino‐orbital disease: Cadaver study with clinical correlations (2011)

Abstract Objectives: Access to the medial orbit traditionally has been gained transcutaneously, with potential for associated soft tissue and lacrimal disruption. Endoscopic transnasal approaches to the medial orbit may be limited in certain scenarios by tumor presence or patient‐specific factors. The medial transconjunctival approach, or transcaruncular approach, has been recently described for access to the medial orbit in orbital decompression and repair of medial blowout fractures. The aim of this study is to determine the utility of this minimally invasive external approach in the endoscopic management of advanced sino‐orbital disease. Methods: This is a cadaver study with additional clinical correlations. The transcaruncular approach was combined with a transnasal endoscopic approach in cadaver dissections performed on eight sides. Five cases are described in which the transcaruncular approach was used as an adjunctive technique in advanced endoscopic sinus surgery. Results: In cadaver dissection, the transcaruncular approach is a simple, reliable method to ligate the ethmoid arteries and place bony cuts along the medial orbital wall. In certain anatomic configurations, supraorbital dissection into the frontal sinus or anterior fossa may be achieved. In the cases examined, exposure of the medial orbital subperiosteal plane allowed for ligation of ethmoid arteries, assessment of periorbital invasion of disease, assistance in tumor dissection, and placement of a malleable retractor for protection of orbital contents. Conclusions: The transcaruncular approach to the medial orbit has certain advantages over the traditional open approach. Ligation of the ethmoid arteries, assessment of the lacrimal sac and periorbita for tumor invasion, protection of orbital contents, and en bloc resection of the periorbita and lamina papyrecea are possible through this route.
Microcavity effect on the electron-hole relative motion in semiconductor quantum wells (2003)

We rigorously find that for a quantum well embedded within a semiconductor microcavity near resonance with the $1s$-exciton transition, the upper (lower) polariton is associated with an electron-hole relative-motion probability-density distribution larger (smaller) than the two-dimisional exciton Bohr radius if half the normal-mode splitting exceeds the $1s$-exciton binding energy. In this case, the exciton continuum comprises an essential part of the description of the upper mode, leading to a strong asymmetry of the microcavity lines observed in transmission.
Mutation analysis in CD40 ligand deficiency leading to X‐linked hypogammaglobulinemia with hyper IgM syndrome (1996)

Mutations in the gene encoding CD40 ligand have been shown to be the cause of X-linked hypogammaglobulinemia with hyper IgM (HIGM1). We have used the technique of single strand conformational polymorphism (SSCP) analysis to screen for mutations in this gene in affected boys from nineteen unrelated families. Sixteen novel mutations were identified in patients, comprising six patients with single base substitutions, two patients with single base insertions, six patients with deletions ranging from one to seven bases and two patients with large deletions at the 5′ end of the gene. These mutations were distributed throughout the gene. SSCP band shifts and/or alterations in restriction enzyme digestion sites could be used for unambiguous determination of carrier status in at-risk female relatives of most of the affected boys and, in some cases, prenatal diagnosis also can be offered. © 1996 Wiley-Liss, Inc.
Detection of Helicobacter pylori virulence-associated genes (2001)

Helicobacter pylori is an important human pathogen and persistent colonization of the human gastric mucosa can cause severe gastrointestinal diseases. The bacterium should not be considered as a uniform organism, but as a population of closely related and yet genetically diverse bacteria. Several genes of H. pylori (such as vacA and cagA) have been identified as being virulence-associated and may have important clinical and epidemiological implications. Assessment of virulence-associated genes of H. pylori should be included in clinical and epidemiological studies as well as therapeutic trials, in order to stratify between patient groups, harboring H. pylori strains with particular virulence genotypes. Molecular determination of antibiotic resistance will be especially useful for treatment studies. Together with our increasing knowledge about the human genome, typing of H. pylori will facilitate the management of gastroenterological pathologies.
Mannose-Binding Lectin Genotypes and Susceptibility to Epstein-Barr Virus Infection in Infancy (2010)

In a cohort study of children < 4 years of age in Greenland, mannose-binding lectin (MBL2) genotypes and Epstein-Barr virus (EBV) antibody levels were determined. EBV seropositivity was significantly lower and time to seroconversion increased in MBL-insufficient compared with MBL-sufficient children, indicating that MBL may be involved in primary EBV infection in infancy.
Multiple mechanisms of protein kinase C inhibition by triphenylacrylonitrile antiestrogens (1990)

The activation of type I (gamma), II (beta) and III (alpha) protein kinase C (PKC) subspecies by phosphatidylserine (PS) and diacylglycerol (DAG) is inhibited by micromolar concentrations of triphenylacrylonitrile (TPE) antiestrogens. TPE A (with p-hydroxy and p-diethylaminoethoxy groups on the 3- and 3'-phenyl rings, respectively) interacts with PS-vesicles as well as with the regulatory domain of PKC, probably at a site different from the Ca2+ and DAG binding sites. The interaction of TPE A with the regulatory domain of enzyme is very slow. Apparently, TPE A does not interact with the catalytic domain of PKC. In contrast, another TPE derivative, TPE B (with a p-hydroxy group on each of the three phenyl rings) inhibits the enzyme activity in a competitive manner with respect to ATP, suggesting that this TPE interacts with the catalytically active site of the enzyme. It seems likely that various TPE antiestrogen derivatives may exert their inhibitory action on PKC by multiple different mechanisms.
An Axiomatic Proof Technique for Networks of Communicating Processes (1979)

this report was supported by Hitachi Corporations 1o Networks of Processes This paper suggests methods for proving the correctness of networks of processes which communicate exclusively through messages
Involvement of NADPH Oxidase 1 in Liver Kinase B1-Mediated Effects on Tumor Angiogenesis and Growth (2018)

The liver kinase B1 (<i>LKB1</i>) gene is a tumor suppressor with an established role in the control of cell metabolism and oxidative stress. However, whether dis-regulated oxidative stress promotes growth of LKB1-deficient tumors remains substantially unknown. Through <i>in vitro</i> studies, we observed that loss of LKB1 perturbed expression of several genes involved in reactive oxygen species (ROS) homeostasis. In particular, this analysis evidenced strongly up-modulated NADPH oxidase 1 (<i>NOX1</i>) transcript levels in tumor cells lacking LKB1. NOX1 accounted in part for enhanced cytotoxic effects of H<sub>2</sub>O<sub>2</sub>-induced oxidative stress in A549 LKB1-deficient tumor cells. Notably, genetic and pharmacologic inhibition of NOX1 activity reduced angiogenesis and growth of A549 tumors in mice. These results suggest that NOX1 inhibitors could counteract ROS production and the angiogenic switch in LKB1-deficient tumors.
Effects ofCycloheximide on Abscisic AcidBiosynthesis and Stomatal Aperture inBeanLeaves1 (1990)

Cycloheximide wasshowntoblock abscisic acid(ABA)biosynthesis innonstressed aswellasinstressed Phaseolus vulgaris leaves. Leafwilting causedbycycloheximide resulted fromincreased stomatal opening asjudged byadecreased stomatal diffusion resistance. Theinhibition ofABAbiosynthesis bycycloheximide wasatleast partially responsible fortheincrease in stomatal opening assuggested bythecooccurrence ofinhibition ofABAbiosynthesis andincreased stomatal opening, andthe partial reversal ofstomatal opening incycloheximide-treated leaves byexogenous ABA.Dark treatment failed toclose stomatal incycloheximide-treated
Dynamic Cine-Computed Tomography Angiography Imaging of Standard and Fenestrated Endografts: Differing Effects on Renal Artery Motion (2008)

Different endograft configurations (fenestrated, transrenal, infrarenal) may varyingly affect aortic side branch movement. Renal artery motion was evaluated with 64-slice dynamic cine-computed tomography angiography before and after endovascular aneurysm repair in 16 patients (46 renal arteries). Center-of-mass displacement of the renals was determined per heartbeat for before repair for 3 different endografts; differences were compared, with significance at P < 0.5. Preoperative renal artery motion is significant (1.2 [SD 0.5] mm, range, 0.6-2.). Neither transrenal nor infrarenal endografts alter renal artery motion compared with before repair (P < .05). Renal artery motion after fenestrated endovascular repair with renal stents reduces motion to 25% of the preoperative value (0.3 [SD, 0.1] mm, range, 0.2-0.5 mm; P = .01). Endograft implantation without stented side branches does not change renal artery motion, potentially allowing significant movement of the renal artery relative to the fenestration. Routine stenting of fenestrations limits postoperative renal artery motion to 0.3 mm, thereby preventing significant branch movement in relation the fenestration.
MONITORING POWER PLANT EFFICIENCY USING THE MICROWAVE-EXCITED PHOTOACOUSTIC EFFECT TO MEASURE UNBURNED CARBON (2003)

Three test instruments are being evaluated to determine the feasibility of using photoacoustic technology for measuring unburned carbon in fly ash. The first test instrument is a single microwave frequency system previously constructed to measure photo-acoustic signals in an off-line configuration. This system was assembled and used to test parameters thought important to photo-acoustic signal output. A standard modulation frequency was chosen based upon signal to noise data gained from experimentation. Sample heterogeneity was tested and found not to be influential. Further testing showed that sample compression and photo-acoustic volume do affect photo-acoustic signal with photoacoustic volume being the most influential. Testing in the fifth quarter focused on microwave power stability. Simultaneously, a second instrument is being constructed based in part on lessons learned with the first instrument, but also expands the capabilities of the first instrument by allowing a spectrum of microwave frequencies to be tested up to 10 GHz. The power amplifiers for this second instrument were completed and tested. Improvements were made to the current leveling loop, which will stabilize the microwave power. This loop is currently in operation with the single frequency cell. Discriminatory measurements are continuing in an attempt to differentiate between magnetic contaminants such as iron and non-magnetic contaminants such as carbon. A short coaxial test fixture was fabricated and tested showing the promise of another microwave based test method for determining carbon content in fly ash. Preliminary design iterations for the third on-line instrument (based on the experiences of the first two instruments) have begun.
Observation of plastic deformation in freestanding single crystal Au nanowires (2006)

Freestanding single crystal nanowires of gold were fabricated from a single grain of pure gold leaf by standard lithographic techniques, with center section of 7μm in length, 250nm in width, and 100nm in thickness. The ends remained anchored to a silicon substrate. The specimens were deflected via nanoindenter until plastic deformation was achieved. Nonlocalized and localized plastic deformations were observed. The resulting force-displacement curves were simulated using continuum single crystal plasticity. A set of material parameters which closely reproduce the experimental results suggests that the initial critical resolved shear stress was as high as 135MPa.
Message from the General Chairs and Program Chairs (2020)

Presents the introductory welcome message from the conference proceedings. May include the conference officers' congratulations to all involved with the conference event and publication of the proceedings record.
Location registration and paging in mobile satellite systems (2002)

Mobile satellite systems are a crucial component of the future global telecommunications infrastructure. An important aspect of the future system is to manage the location of both users and satellites. This paper presents a strategy for location registration (update) and paging in low Earth orbit (LEO) mobile satellite systems. First, we discuss the tradeoff that exists between four proposed satellite location area designations. Then we introduce a scheme that selects a simple location area design and uses a hierarchical database architecture to reduce the location management signaling delay. The performance of the scheme is analyzed in terms of the paging bandwidth and the location update signaling delay. Finally, we present the numerical results for several planned systems, such as GlobalStar, ICO, and IRIDIUM.
X-Ray crystallographic and extended X-ray absorption fine structure studies of gold(I) complexes containing weak intermolecular interactions (1998)

The crystal and molecular structures of [Au2{S2CN(C2H4OMe)2}2], [Au(PPh3)(SCH2CO2H)], [Au(PPh3)(SCMe2CO2H)] and [Au(PPh3)(SCH2CO2Me)] have been determined. All compounds contain an approximately linear primary co-ordination sphere of ligands about the gold atom, but they differ markedly in their type of intermolecular interaction. In [Au2{S2CN(C2H4OMe)2}2] the supramolecular array is dominated by an almost linear, polymeric backbone of gold atoms with alternate gold–gold contacts of 2.7902(6) (intramolecular) and 3.1572(7) Å (intermolecular), whereas in [Au(PPh3)(SCH2CO2H)] dimers associated through long gold–sulfur contacts of 3.131(2) Å are held together in a polymeric chain by hydrogen bonding between neighbouring carboxylic acid residues. The increased steric bulk of the thiolate ligand in [Au(PPh3)(SCMe2CO2H)] caused by the methyl groups on the α-carbon atom precludes association of the gold centres, but hydrogen bonding between carboxylates as in the SCH2CO2H compound causes dimerisation. Compound [Au(PPh3)(SCH2CO2Me)] exists as a monomer with no evidence of weak intermolecular interactions. Analysis of ambient-temperature EXAFS (extended X-ray absorption fine structure) measurements on solid samples of the first two compounds yield gold–gold separations of 2.775(2) and 3.271(6) Å and 4.188(15) Å, respectively. Gold–sulfur separations of 2.290(1) and 3.532(8) and of 2.329(4) and 3.124(19) Å, respectively, are also in good agreement with X-ray data.
木质素芳香族化合物降解菌Sphingobium sp. SYK-6的研究进展 (2014)

木质素是木质的主要成分之一,在自然界中,高分子木质素被真菌的胞外酶分解成低分子芳香族化合物,然后土壤细菌将其完全降解为二氧化碳。由此可见,木质素的完全降解过程是真菌和细菌的共同作用。研究细菌的降解机制,一方面可以理解芳香族化合物在生态系中的碳素循环,另一方面可以为木质素的有效利用提供基因和酶工具,将可再生资源的木质素转化成高附加价值的工业产品。Sphingobium sp.SYK-6是1987年从造纸厂废水中以木质素中的联苯化合物（5,5’-脱氢联香草酸）作为唯一碳源分离出的木质素化合物降解菌。在长达25年以上的研究中我们阐明了一系列芳香族化合物的代谢途径,克隆了相关基因,2012年随着基因组测序的完成,整个降解功能的全貌展现出来。介绍内容：（1）基因组信息;（2）芳醚化合物代谢;（3）联苯化合物代谢;（4）阿魏酸代谢;（5）木质素化合物降解过程中四氢叶酸依赖型机制;（6）原儿茶酸4,5开环途径;（7）3-甲氧基没食子酸代谢的多样性;（8）应用研究。我们希望SYK-6菌株成为一个让人们理解木质素化合物降解的模式菌株。最后结合课题组现在的研究课题展望了木质素化合物的降解研究的发展方向。