gebhart/patrepeval huggingface dataset:
The temperature-sensitive bond in human alpha 2-macroglobulin is the alkylamine-reactive site. (1980)

Human a2-macroglobulin undergoes an autolytic peptide cleavage to give two large peptides, fragment I (M, = 115,000) and fragment I1 (Mr = 65,000) which account for the entire mass of the native subunits.This fragmentation, which was first reported by Harpel et al.
Caffeine‐ and Aminophylline‐Induced Seizures (1981)

The epileptogenicity of caffeine and aminophylline was studied in rats. Intraperitoneal administration of caffeine produced an immediate excitation and seizures followed by an encephalopathy. A progression from encephalopathy to seizures was observed following aminophylline administration. During the development of behavioral seizures, the EEGs showed a progression from fast activity isolated or bursts of spikes and/or sharp waves to full-blown epileptiform discharges. A wide spectrum of cardiac arrhythmias was observed during and following the seizures. Epileptiform activities ranging from isolated or bursts of spikes and/or sharp waves to continuous epileptiform discharges were observed following local application of the drugs to the cerebral cortex.
Dynamic Stateless GRE Tunnel (2014)

Generic Routing Encapsulation (GRE) is regarded as a popular
encapsulation tunnel technology. When a node tries to encapsulate the
user traffic in GRE, it needs the IP address of the destination node
which decapsulates the GRE packets. In practice, the GRE tunnel
destination IP address may be manually configured. This configuration
may introduce efficiency issues for operators. This work proposes an
approach to configure the GRE information dynamically.
Hyperphosphatemia is associated with anemia in adults without chronic kidney disease: results from the National Health and Nutrition Examination Survey (NHANES): 2005–2010 (2013)

Hyperphosphatemia, serum phosphorus ≥ 4.4 mg/dL, is associated with increased risk for chronic kidney disease and cardiovascular disease. Previous studies have shown a weak association between dietary phosphorus intake and serum phosphorus concentrations. While much less common in the general population, hypophosphatemia (< 2.5 mg/dL) may be associated with metabolic syndrome and obesity. Using three cycles from the National Health and Nutrition Examination Survey (NHANES) (2005–2010), this study evaluated independent risk factors for hyperphosphatemia and hypophosphatemia. Risk factors for hyperphosphatemia included higher adjusted calcium (OR 2.90, 95% CI 2.43-3.45), increasing cholesterol (OR 1.003, 95% CI 1.001-1.005), female gender (OR 1.61, 95% CI 1.39-1.87) and low hemoglobin (OR 1.52, 95% CI 1.17-1.98). Advanced age was protective (OR 0.98, 95% CI 0.977-0.987). Models that included fasting serum glucose found lower body mass index (BMI) to be protective (OR 0.97, 95% CI 0.96-0.99) and adjusting for serum vitamin D and parathyroid hormone removed the association with low hemoglobin and BMI. Risk factors for hypophosphatemia included the following protective factors: higher albumin (OR 0.56, 95% CI 0.35-0.93), higher BUN (OR 0.90, 95% CI 0.86, 0.95), corrected calcium (OR 0.38, 95% CI 0.23-0.63) and female gender (OR 0.47, 95% 0.24-0.94). In men, higher fasting glucose levels increased risk (OR 1.01, 95% CI 1.0004-1.01). This study is the first to show an association between low hemoglobin levels and increased risk for hyperphosphatemia among individuals without chronic kidney disease. We did not find any association between diabetes mellitus, increasing BMI or fasting glucose levels and hypophosphatemia.
Method for measuring magnetic moments with precision (1974)

The induction method for measuring magnetizations is reviewed briefly and it is shown that a simple modification in the usual coil geometry should allow the absolute measurement of the changes in the magnetic moment of a small sample. The time integral of the voltage induced in a long pickup coil is shown to be proportional to the volume integral of one component of the change in magnetization within the coil. Experimental procedures which would make use of this fact to attain accuracies of better than one part in 104 are suggested.
Neural contribution to the effect of glucagon-like peptide-1-(7—36) amide on arterial blood pressure in rats (1999)

This study was designed to determine the contribution of the central nervous system (CNS) to the effects of glucagon-like peptide-1-(7—36) amide (tGLP-1) on arterial blood pressure and heart rate in rats. Accordingly, intracerebroventricular administration of the peptide produced an increase in cardiovascular parameters, which was blocked by previous administration of exendin-(9—39) through the same route, but not when it was intravenously injected. Intravenous administration of tGLP-1 produced a significant increase in arterial blood pressure and heart rate, which was blocked by the previous intracerebroventricular or intravenous administration of exendin-(9—39). Bilateral vagotomy blocked the stimulating effect of intracerebroventricular tGLP-1 administration on arterial blood pressure and heart rate. Also, bilateral vagotomy prevented the blocking effect of intracerebroventricular but not of intravenous exendin-(9—39) on cardiovascular parameters after intravenous administration of tGLP-1. These findings suggest that the action of tGLP-1 on cardiovascular parameters is under a dual control generated in the CNS and in peripheral structures and that the neural information emerging in the brain is transmitted to the periphery through the vagus nerve.
4-Aminomethyl-4'-aminodiphenylsulfone and Related Compounds<sup>*</sup> (1957)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXT4-Aminomethyl-4'-aminodiphenylsulfone and Related Compounds*WILHELM WENNERCite this: J. Org. Chem. 1957, 22, 11, 1508–1513Publication Date (Print):November 1, 1957Publication History Published online1 May 2002Published inissue 1 November 1957https://pubs.acs.org/doi/10.1021/jo01362a050https://doi.org/10.1021/jo01362a050research-articleACS PublicationsRequest reuse permissionsArticle Views112Altmetric-Citations4LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
“Plug-and-Go” Strategy To Manipulate Streptavidin Valencies (2014)

The streptavidin-biotin set is one of the most widely utilized conjugation pairs in biotechnological applications. The tetravalent nature of streptavidin and its homologues, however, tends to result in such undesirable complications as cross-linking or ill-defined stoichiometry. Here, we describe a mutagenesis-free strategy to manipulate the valencies of wild-type streptavidin that only requires commercially available reagents. The basic idea is simple: one obtains the desired streptavidin valency by blocking off unwanted binding sites using ancillary biotin ("plug"); this way, the extraordinary fM-biotin-binding affinity is fully retained for the remaining sites in streptavidin. In the present implementation, the ancillary biotin is attached to an auxiliary separation handle, negatively charged DNA or His-tagged protein, via a photochemically or enzymatically cleavable linker. Mixing streptavidin with the ancillary biotin construct produces a distribution of streptavidin valencies. The subsequent chromatographic separation readily isolates the construct of desired streptavidin valency, and the auxiliary handles are easily removed afterward ("go"). We demonstrate how this "plug-and-go" strategy allows a precise control for the compositions of streptavidin-biotin conjugates at the single-molecule level. This low-entry-barrier protocol could further expand the application scope of the streptavidin technology.
A powder neutron diffraction study of λ and γ manganese dioxide and of LiMn~2~O~4~ (1994)

The structure of two polymorphs of manganese dioxide, λ-MnO 2 and γ-MnO 2 and the spinel oxide LiMnO 2 have been refined by Rietveld analysis of powder neutron diffraction data. λ-MnO 2 , Fd3m, a=8.0639(3) A, R Bragg =1.81%, γ-MnO 2 , Pnam, a=9.3229(11) A, b=4.4533(7) A, c=2.8482(3) A, R Bragg =1.34% and LiMn 2 O 4 , Fd3m, a=8.2468(2) A, R Bragg =2.33%
Active zoom cameras control system using stereo parallax (2010)

Many binocular active tracking systems can track the target by vergence. However, the small vergence angle affects the vergence tracking in wide area. Furthermore, the scale variant problem will also disable the vergence tracking. To get a wide area security, we suggest installing a zoom control method to keep the target in the centre of the image instead of relying on vergence. We propose an active zoom camera system combining the monocular eagle vision and binocular eagle vision. The monocular eagle vision can get a wider field of view (FOV) in high resolution for detection. The binocular eagle vision can maintain the stereo parallax for tracking and zooming. This active zoom camera system can perform four kinds of human eye movements, including the first saccade, the second saccade, smooth pursuit and vergence. We set three zoom cameras at different focal lengths as the peripheral camera for the first saccade, the shallow fovea camera for the second saccade and the deep fovea camera for smooth pursuit. After the first saccade, the peripheral camera zooms in to the same focal length as the deep fovea camera to get the binocular eagle vision. When the deep fovea camera catches the target, the stereo parallax can be calculated to control the smooth pursuit and zooming. At the same time, the constant size of the remote target and the depth of the target can keep the tracking robust. During the smooth pursuit tracking, the shallow fovea camera can provide a wide FOV to avoid the smooth pursuit failure. The parallel processing of zoom control and smooth pursuit tracking control is done in real-time. We report the experiment result of tracking a remote pedestrian from 165 to 110 meters using the stereo parallax. Experimental results show the constant stereo parallax can be attained by zoom control. The zoom tracking can keep the target in the centre of the image as the vergence tracking.
Oxidative mineralization and characterization of polyvinyl alcohol for compatibility with tank farm processing chemistry (2000)

Polyvinyl alcohol (PVA) material has been evaluated for use as a cost-effective substitute for conventional cellulose-based disposal materials (decontamination mops and wipes), plastic bags, and disposable personal protection clothing, that are currently used at Savannah River Site. This study also provides process design criteria for ultraviolet/ultrasonic/hydrogen peroxide PVA reactor system.
Bacteriocin production by spray-dried lactic acid bacteria (2002)

Spray-drying is a potentially useful process for large scale production of dried powders containing viable organisms with antagonistic activity against pathogens.
Inter-α-Trypsin Inhibitor of Human Serum: An Inhibitor of Polymorphonuclear Granulocyte Elastase (1983)

Inter-alpha-trypsin inhibitor (ITI) was separated from human serum in a single step using ion-exchange chromatography via the fast protein liquid chromatographic system. The inhibitor preparation, identified as ITI by specific immunological assays, inhibited human polymorphonuclear granulocytic elastase besides bovine trypsin. Hence, ITI is the third candidate of the plasma proteinase inhibitors (in addition to alpha 1-proteinase inhibitor and alpha 2-macroglobulin) capable of inhibiting lysosomal granulocytic elastase.
Irregular π-rotation LDPC codes (2004)

We present irregular /spl pi/-rotation LDPC codes by extending the classic /spl pi/-rotation parity check matrix to allow irregular column weight and choice of many code rates. The irregular /spl pi/-rotation codes are defined with a small set of parameters providing the exact definition of the code with its performance. The encoding circuit is based on the original /spl pi/-rotation design and thus users have the choice of using regular or irregular matrix patterns and various code rates without changing the encoding circuitry. We compare the performance of the irregular /spl pi/-rotation code against the binary Shannon limit for several rates.
The Capability of Pulsed Neutron Capture Logging To Determine Oil and Gas Saturations (1989)

Abstract The capability of current pulsed neutron capture logging technology for determining oil and gas saturations has been investigated. The currently advancing technology provides more accurate saturation determination, leading to better reservoir management and hence more economic production than hitherto. Experiments have been carried out at our laboratory test facility with various commercially available logging tools. This has increased our understanding of the physical processes in pulsed neutron capture, such as the diffusion of thermal neutrons. The derived log value depends strongly on the way these effects are taken into account in the processing. Examples are shown of the results of various processing techniques. The comparison between different tools has led to recommendations for field applications. In addition to the experimental work, the basic tool response (the pulsed neutron decay) has been numerically simulated. With a Monte Carlo simulator, the detector count rates were modelled for several combinations of formation and borehole contents. In addition, the influence of porosity on the tool response has been investigated. In this way, the conclusions from the experimental results were extended. The details of a number of pulsed neutron capture tools were studied. As a result of these studies, a reprocessing technique was developed for one of these tools to simulate the log that would have been obtained by its predecessor. This enables time-lapse comparisons of the logs from the new generation of tools with previously obtained logs.
Native β‐glucuronidase activity in sugarbeet (<i>Beta vulgaris</i>) (1994)

β‐Glucuronidase (EC 3.2.1.31) activity, initially thought absent from plants, has been found in a number of plant families. During an analysis of Agrobacterium ‐mediated transformation of sugarbeet ( Beta vulgaris L.), significant glucuronidase activity was observed in control (non‐transformed) tissues when the fluorogenic substrates 4‐methylumbelliferyl‐β‐ d ‐glucuronic acid, resorufin glucuronic acid and 3‐carboxyum‐belliferyl‐β‐ d ‐glucuronic acid were used to quantify β‐glucuronidase activity under standard protocol conditions. Similarly, the colorigenic substrate p ‐nitrophenyl‐β‐ d ‐glucuronide was hydrolyzed by this sugarbeet‐derived glucuronidase. Biochemical and immunological data are presented to indicate significant differences between sugarbeet‐derived glucuronidase and that from Escherichia coli (EC 3.2.1.31) encoded by gusA . These differences provide means of distinguishing between the two activities in extracts that contain a mixture of both. Use of X‐glue, the substrate utilized in histochemical localizations of glucuronidase activity, gave no reaction product (i.e., indigo precipitate) at pH 7.0. However, at pH 3.0, 4.0 and 5.0 formation of the indigo precipitate was evident within 1 h at 37°C in sugarbeet callus and by 4 h in leaves and petioles. The specific activity of sugarbeet glucuronidase was observed to be strongly pH dependent, with an optimum near pH 4.0. The use of various β‐glucuronidase assay techniques as applied to transformation of sugarbeet is discussed.
Development of Porosity upon Chemical Activation of Kraft Lignin with ZnCl<sub>2</sub> (1997)

Chemical activation of kraft lignin with ZnCl2 allows one to obtain high surface area activated carbons with a predominantly microporous structure. Most of porosity develops within the thermal range of 400−500 °C, where an increase of temperature leads to increasing micropore volume values (up to ≈1 cm3/g) and a wider distribution of micropore size. An increasing mesoporositiy is also observed. Increasing the impregnation ratio (ZnCl2/lignin, wt) has a similar effect on the evolution of the porous structure. The mesopore distribution remains within the low-size range even at high impregnation ratios (up to 2.3). At 500 °C and an impregnation ratio of 2.3, where the highest contribution of mesoporosity was observed, the mesopore volume reached a value of 0.59 cm3/g. These conditions allowed us to obtain a BET surface area of 1800 m2/g, including the external or non-microporous surface of 200 m2/g. The porous structure developed suggests a fairly homogeneous distribution of the activating agent favored by the softening and partial fusion which kraft lignin undergoes within the temperature range of 180−280 °C.
Fabrication and phonon transport studies in nanometer scale free-standing wires (1987)

We have fabricated free-standing structures of nanometer-scale dimensions by combining high-resolution electron beam lithography, layer growth and dry etching techniques. AuPd lines having a minimum width of 40 nm, a thickness of 10 to 40 nm, and lengths from 8 to 120 μm have been made free standing. The resistance of fine wires on a substrate as well as free-standing wires has been measured from 0.35 to 20 K. Both sets of wires show quantum corrections to the resistance. For wires on a substrate the resistance rise fits well to one-dimensional electron–electron interactions, while for the free-standing wires the resistance rise takes a new form that has not yet been explained. Below 1 K the lattice component of the thermal conductivity is expected to change as the phonon dimensionality is reduced from three to one. This contribution to the thermal conductivity can be estimated from self-heating measurements, and it is found to be three orders of magnitude smaller than predicted. In addition we have estimated the tensile strength to be an order of magnitude larger than bulk values.
Sampling the mesoscale ocean surface currents with various satellite altimeter configurations (2004)

Ten-day composites of maximum cross-correlation (MCC) ocean surface current vectors from 1-km spatial resolution Advanced Very High Resolution Radiometer (AVHRR) 11-/spl mu/m thermal infrared images are used to simulate the ocean surface current retrieval capabilities of three satellite altimeter configurations over a large California coastal region. Ground track positions of the nadir sampling TOPEX/Poseidon (TP; now the Jason-1) satellite altimeters are used to compute the cross-track velocity components from the corresponding optimally interpolated MCC vectors for a ten-day period. Next, the Jason-1-only and the TP plus Jason-1 "tandem mission" sampling are simulated as well as the combination of all available satellite altimeters including European Remote Sensing Satellite 2 and Geosat Follow-On. Finally, we simulate surface current retrievals from the proposed Wide Swath Ocean Altimeter (WSOA), which will have both along- and cross-track velocity components over a spatial swath. Comparisons of vector current fields, their differences, and wavenumber spectra from optimally interpolated maps of the "simulated altimetry velocities" with the corresponding MCC field indicates that (1) the combined coverage from Jason-1 plus TP as well as the combination of all available satellite altimeters results in a better representation of the currents than that of Jason-1 alone and (2) the retrieved currents from the WSOA provide an even greater improvement over the tandem mapping and multiple satellites. It will be possible in the future to regularly map the mesoscale surface currents of the ocean with wide-swath ocean altimeters.
Mechanistic aspects of enzymatic carbohydrate epimerization (2002)

Carbohydrate epimerases are enzymes that catalyze an inversion of stereochemistry at a stereogenic center in a sugar. This review focuses on the mechanistic strategies that are employed by this diverse family of enzymes, and is divided into the following sections: deprotonation/reprotonation, transient oxidation, cofactor independent, and mutarotation. The review is comprehensive up to Oct. 2001 and contains 216 references.
Scalable e-business social network using MultiCrawler agent (2008)

Social networking is a big buzz phrase nowadays. It refers to the practice of interacting with others online via blogs, forums, social media sites and other outlets. The importance of social networking is to let others know that we are exists. Social network can show how people in our extended network are related to each other. In this paper, we are focusing on e-business network since e-business is sprouting on the Internet these days like wild mushrooms. Moreover, with the rapid growth of the e-business in the Web, searching the popular web page of e-business and its relationship with others web page becomes an interesting and important issue for the user especially for the firms. Currently, we realized which of the e-business having the highest popularity via the newspaper, magazines and Internet. However, the e-business having a lack of information - the quality of the connection. In order to collect the e-business web sites from the Internet, crawler agent is used. The crawler will obtain information in the links and keeps the information in the repository for later processing. Here, we proposed the MultiCrawler agent to develop a scalable e-business social network. The genetic algorithm is used to optimize the e-business web pages fetched by the crawler based on the user profiles. The result is the visualization of e-business social network mapping that related to the Multimedia Super Corridor (MSC) companies in Malaysia.
Business rules domains and business rules modeling (2004)

This article is focused on the enterprise business rules, which can be associated with the enterprise information system client-server communications. By generalizing four major types of inter-application (or inter-service) communication protocols, the article introduces a formal model for horizontal business rules, which can be associated with such communications.
Evoninoate Sesquiterpene Alkaloids from the Stem of Celastrus paniculatus (2006)

Two novel evoninoate sesquiterpene alkaloids, paniculatine A (4) and paniculatine B (5) with two known, euonymin (2) and wifornine F (3), were isolated from the stem of Celastrus paniculatus.The structures of the new compounds were elucidated by 2D NMR techniques and spectral comparison.The configuration of C-2' and C-3' of 2 and 3 was determined for the first time by spectral comparison.