gebhart/patrepeval huggingface dataset:
An Improved Harvest and<i>in Vitro</i>Expansion Protocol for Murine Bone Marrow-Derived Mesenchymal Stem Cells (2010)

Compared to bone marrow (BM) derived mesenchymal stem cells (MSCs) from human origin or from other species, the in vitro expansion and purification of murine MSCs (mMSCs) is much more difficult because of the low MSC yield and the unwanted growth of non-MSCs in the in vitro expansion cultures. We describe a modified protocol to isolate and expand murine BM derived MSCs based on the combination of mechanical crushing and collagenase digestion at the moment of harvest, followed by an immunodepletion step using microbeads coated with CD11b, CD45 and CD34 antibodies. The number of isolated mMSCs as estimated by colony forming unit-fibroblast (CFU-F) assay showed that this modified isolation method could yield 70.0% more primary colonies. After immunodepletion, a homogenous mMSC population could already be obtained after two passages. Immunodepleted mMSCs (ID-mMSCs) are uniformly positive for stem cell antigen-1 (Sca-1), CD90, CD105 and CD73 cell surface markers, but negative for the hematopoietic surface markers CD14, CD34 and CD45. Moreover the immunodepleted cell population exhibits more differentiation potential into adipogenic, osteogenic and chondrogenic lineages. Our data illustrate the development of an efficient and reliable expansion protocol increasing the yield and purity of mMSCs and reducing the overall expansion time.
Glass Fiber Reinforced Rubber Products (1965)

<div class="htmlview paragraph">The introduction of glass as a reinforcement for mechanical rubber goods for automotive applications represents another milestone in the ever expanding uses of glass. This new-old material has basic properties which offer the engineer a new dimension.</div> <div class="htmlview paragraph">Fiberglas reinforced tires will permit the automotive design engineer a greater flexibility in design of suspension systems since they offer stabilized tire characteristics which do not change with conditions of use.</div> <div class="htmlview paragraph">This paper covers the status of the development program aimed at the introduction of glass as a tire reinforcement.</div>
Predicting Biomass of Beaver Food from Willow Stem Diameters (1995)

Beaver (Castor canadensis Kuhl) and willow (Salix spp.) are important components of riparian restoration on degraded western rangelands. Land managers need quantitative information to evaluate carrying capacity and potential habitat quality for beavers in riparian-willow systems. Our objectives were to determine the best model to predict biomass components of coyote willow (S. exigua Nuttall) from basal stem diameters and compare model predictions to diameter class averages. The study was conducted in a shrub-steppe ecosystem of northwestern Colorado. We estimated oven-dried weights of annual and total beaver food and total live biomass by diameter class from a sample of 160 willow stems. Several variants of a logistic function were fit with nonlinear least squares regression to select a model that best predicted mean biomass by stem diameter. A four-parameter logistic model provided the best fit for all 3 stem components. Predicted biomass estimates of beaver food and total live biomass had smaller standard errors than sample means for all 10 stem diameter class midpoints. Percentage of stem weight that was beaver food varied from 93.6% for the smallest stems to 12.2% for the largest. We concluded that the logistic model provided reliable estimates of beaver food biomass and could be used with food consumption rates and stem density data to evaluate carrying capacity for beaver or test assumptions in the beaver habitat suitability index model.
Antifungal activity of Comamonas acidovorans isolated from water pond in south Jordan (2007)

A bacterial strain identified as Comamonas acidovorans NB-10II was isolated from water pond in South Jordan. It was found to have an antifungal activity against filamentous fungi (Aspergillus niger SQ 40, Fusarium oxysporium SQ 11,Verticillium dahliae SQ 42), yeasts (Saccharomyces cerevisiae SQ 46, Candida albicans SQ 47). All gram-positive bacteria (Bacillus megaterium SQ 5, Bacillus cereus SQ 6, Staphylococcus aureus SQ 9, Streptococcus pyogenes SQ 10) and gram-negative bacteria (Escherichia coli SQ 22, Klepsiella spp SQ 33,Pseudomonas mallei SQ 34) were found to be resistant. The isolate NB-10II was found to accumulate the main portion of the antimicrobial substances in their cells. In batch culture, the active antimicrobial substances accumulated at the late growth cycle, reaching their maximum at 42 h of growth. The data clearly show an antifungal activity ofC. acidovorans against filamentous fungi and yeasts, and indicated the possibility of using NB-10II as a source of antimicrobial substances or as a biocontrol agent of some plant diseases in Jordan.   Key words: Antifungal activity, Comamonas acidovorans, Pseudomonas.
Colpitts-Oscillator-Type Micro-Magnetic Sensor Using Amorphous MI Elements. (1995)

A Colpitts-oscillator-type field sensor was constructed using Ml-elements (amorphous FeCoSiB wire and CoFeB film) as the inductive components. The oscillation voltage of the circuit changes with the applied magnetic field, owing to the change of impedance of the MI element. Therefore, this sensor operates with amplitude modulation. The sensitivity of a sensor with a 1 mm-long wire head was 0.1 V/Oe, and the resolution of the field detection was about 10-4 Oe. The temperature stability of the sensor was improved by adding an emitter resistance Re to the Colpitts circuit.
Facile Route to an Efficient NiO Supercapacitor with a Three-Dimensional Nanonetwork Morphology (2013)

NiO nanostructures with three distinct morphologies were fabricated by a sol-gel method and their morphology-dependent supercapacitor properties were exploited. The nanoflower- shaped NiO with a distinctive three-dimensional (3D) network and the highest pore volume shows the best supercapacitor properties. The nanopores in flower-shaped nanostructures, offering advantages in contact with and transport of the electrolyte, allow for 3D nanochannels in NiO structure, providing longer electron pathways. The XPS and EIS data of the NiO nanostructure confirm that the flower-shaped NiO, which has the lowest surface area among the three morphologies, was effectively optimized as a superior electrode and yielded the greatest pseudocapacitance. This study indicates that forming a 3D nanonetwork is a straightforward means of improving the electrochemical properties of a supercapacitor.
Discrete operating conditions gas path analysis (1988)

Diagnostic de fonctionnement d'un moteur a turbine a gaz base sur l'analyse du trajet des gaz, les donnees etant obtenues par des capteurs places a differents endroits le long du trajet
Laser micromachining of high-density optical structures on large substrates (2004)

A new laser mask projection technique, Synchronised Image Scanning (SIS), has been developed for the efficient fabrication of dense arrays of repeating microstructures on large area substrates. This paper details the technique and provides specific examples of the type of structures that can be produced. SIS is a laser micro-machining technique where the information for the ablation of a specific 3D feature is stored as a linear array on a chrome-on-quartz mask. The feature is then written by synchronised motion and laser firing, such that the firing frequency of the laser corresponds to the spatial pitch of the features. This requires highly accurate laser triggering with low-jitter signals, and accurate stages with high resolution encoders. An add-in for CAD software has been developed to generate the mask pattern efficiently and error-free, using the 3D designs. SIS allows for major improvements in the accuracy and speed with which 3D patterns can be created over large areas by laser ablation. Feature sizes down to a few microns can be produced with excellent surface quality. Large areas of microstructures have wide ranging applications in many areas. One example is the machining of large polymer master panels for electroforming to produce moulds for replication of display enhancement films.
Pyrethroid-Synergist Mixtures: Toxicity, Resistance, and Field Efficacy Toward Pyrethroid-Resistant Horn Flies (Diptera: Muscidae) (1988)

Permethrin and cyhalothrin in combination with piperonyl butoxide (PB), DEF (S,S,S-tributyl phosphorotrithiolate), pirimiphos-ethyl and -methyl were evaluated in the laboratory and the field for activity against pyrethroid-resistant and susceptible horn flies, Haematobia irritants (L.). Horn fly adults from the pyrethroid-resistant population were resistant to permethrin (12.5-fold) but displayed a lower level of resistance to cyhalothrin and cyhalothrin-K (5.4- and 1.7-fold, respectively). Combinations of permethrin plus PB or DEF or both produced a low level of synergism (1.4 to 4.6-fold) but did not reduce the level of resistance present in the pyrethroid-resistant horn flies. The levels of synergism (2.0- to 6.6-fold) observed for combinations of PB, DEF, and PB + DEF with cyhalothrin were marginally higher than for permethrin. Unlike permethrin, the combination of cyhalothrin + PB + DEF resulted in a decreased level of resistance. Pirimiphos-ethyl and -methyl were highly toxic to the horn fly, with virtually no cross-resistance in the pyrethroid-resistant population. Mixtures of pirimiphos-ethyl plus either permethrin or cyhalothrin were highly effective against the resistant horn fly population, but no more so than pirimiphos-ethyl alone. Field studies in 1985 demonstrated that, although the combination of permethrin + PB + DEF was more effective than permethrin alone, control was still inadequate. In these same studies, cyhalothrin provided marginal control while cyhalothrin + PB + DEF produced good results. In 1986, the use of cyhalothrin-K and pirimiphos-methyl resulted in excellent control of the horn fly throughout the season, as did a higher concentration of cyhalothrin and cyhalothrin + pirimiphos-methyl.
A Review of the Evolution of Diagnostic Practices for Fetal Alcohol Spectrum Disorder. (2004)

Fetal Alcohol Spectrum Disorders (FASD) are characterized by cognitive, emotional, behavioural, and social disabilities. FASD are complex and pose many challenges for clinicians and researchers in the assessment, diagnosis, and intervention process. The variations in amount, timing, and frequency of alcohol that is consumed during pregnancy can produce a wide spectrum of deficits ranging from extremely debilitating impairments to subtle problems that can be easily misdiagnosed. This spectrum often creates confusion as symptoms may be very different between different children, thus making appropriate intervention elusive as well. Failure to accurately identify this population also reduces the opportunities to implement preventative programs. By informing the psychological community of the unique features of this population it is possible that this disorder may become more widely recognized and understood resulting in more accurate diagnoses and creative interventions to prenatal alcohol-related problems. More importantly, children diagnosed with FASD, and their caregivers, are more likely to be provided with the extra support and understanding their condition requires.
Ionic liquids in the synthesis and modification of polymers (2005)

Abstract Ionic liquids are organic salts that are liquid at ambient temperatures, preferably at room temperature. They are nonvolatile, thermally and chemically stable, highly polar liquids that dissolve many organic, inorganic, and metallo‐organic compounds. Many combinations of organic cations with different counterions are already known, and the properties of ionic liquids may be adjusted by the proper selection of the cation and counterion. In the last decade, there has been increasing interest in using ionic liquids as solvents for chemical reactions. The interest is stimulated not only by their nonvolatility (green solvents) but also by their special properties, which often affect the course of a reaction. In recent years, ionic liquids have also attracted the attention of polymer chemists. Although the research on using ionic liquids in polymer systems is still in its infancy, several interesting possibilities have already emerged. Ionic liquids are used as solvents for polymerization processes, and in several systems they indeed show some advantages. In radical polymerization, the k p / k t ratio (where k p is the rate constant of propagation and k t is the rate constant of termination) is higher than in organic media, and thus better control of the process can be achieved. Ionic liquids, as electrolytes, have also attracted the attention of researchers in the fields of electrochemical polymerization and the synthesis of conducting polymers. Finally, the blending of ionic liquids with polymers may lead to the development of new materials (ionic liquids may act as plasticizers, electrolytes dispersed in polymer matrices, or even porogens). In this article, the new developments in these fields are briefly discussed. © 2005 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem 43: 4675–4683, 2005
A pneumatically controllable flexible and polymeric microfluidic valve fabricated via<i>in situ</i>development (2005)

In this paper, we have developed a pneumatically controllable polydimethylsiloxane (PDMS)-based microfluidic valve. This valve regulates 'On/Off' of flow using the thick centered membrane. To integrate the freely moving thick centered membrane, regional bonding of the PDMS layer is required. Here, we integrated such a membrane employing a water soluble mask as a regional bonding method, and the mask was washed out by flowing distilled water. The fabricated valve showed good 'On/Off' operations in accordance with the applied pneumatic pressure source. The flow rate could be regulated by the pressure applied to the inlet (regulated by changes in the height of the water column) and the compression-/vacuum-period ratio (this means the ratio of 'On' and 'Off' periods in each cycle) in the range of a few microliters per minute. For the durability test, ten valves were operated simultaneously one million times, and no failed valves were observed.
Time-Domain Investigating Path Loss Characteristics of UWB Signals in Indoor Line-of-Sight Environment (2006)

Nowadays, the path loss characteristics of UWB signals is widely investigated in the world for providing the channel model to UWB system. In this study, the propagation rules for UWB signals in indoor line-of-sight (LOS) environment are proposed. The relationship between multipath overlapping and the path loss is analyzed mathematically in time-domain. A new 5 rays path loss calculation method, which is satisfactory accurate for indoor LOS environment, is developed based on time-domain theory. The simulation result shows that the path loss can be characterized as 3 zones with different path loss exponent as distance between transmitter and receiver (T-R) increasing, while the path loss exponent within the scope of 2 to 4
The Effect of Tryptophan 2,3-Dioxygenase Inhibition on Kynurenine Metabolism and Cognitive Function in the APP23 Mouse Model of Alzheimer’s Disease (2020)

Alzheimer's disease (AD) is associated with progressive endogenous neurotoxicity and hampered inflammatory regulation. The kynurenine (Kyn) pathway, which is controlled by tryptophan 2,3-dioxygenase (TDO), produces neuroactive and anti-inflammatory metabolites. Age-related Kyn pathway activation might contribute to AD pathology in humans, and inhibition of TDO was found to reduce AD-related cellular toxicity and behavioral deficits in animal models. To further explore the effect of aging on the Kyn pathway in the context of AD, we analyzed Kyn metabolite profiles in serum and brain tissue of the APP23 amyloidosis mouse model. We found that aging had genotype-independent effects on Kyn metabolite profiles in serum, cortex, hippocampus and cerebellum, whereas serum concentrations of many Kyn metabolites were reduced in APP23 mice. Next, to further establish the role of TDO in AD-related behavioral deficits, we investigated the effect of long-term pharmacological TDO inhibition on cognitive performance in APP23 mice. Our results indicated that TDO inhibition reversed recognition memory deficits without producing measurable changes in cerebral Kyn metabolites. TDO inhibition did not affect spatial learning and memory or anxiety-related behavior. These data indicate that age-related Kyn pathway activation is not specific for humans and could represent a cross-species phenotype of aging. These data warrant further investigation on the role of peripheral Kyn pathway disturbances and cerebral TDO activity in AD pathophysiology.
A surface micromachined latching accelerometer (2002)

This paper presents a surface micromachined mechanically-latching accelerometer that is used as a peak reading shock recorder covering the range from tens to thousands of G. This new type of accelerometer consists of a seismic-mass-loaded cantilever beam and an array of circularly distributed notches. The cantilever is latched with increasing acceleration into successive notches to provide a stored measure of peak acceleration. The threshold acceleration can then be read out by electrical or optical techniques. A closed form analytical solution of the acceleration sensitivity has been derived and compared with the experimental data. The model is confirmed experimentally for several acceleration levels. The structures are compatible with standard CMOS processing.
High Voltage Pulse Generator Using Power Semiconductor Switcher (2001)

Using power semiconductor switches such as IGBTs, diodes and L-C circuits, novel repetitive impulse voltage generator is developed. In the presented circuits, high voltage pulse is generated by series-connection of capacitors and IGBTs. Therefore, the high voltage pulse is obtained by circuit configuration without any high voltage pulse transformer and high voltage dc source. Especially, the proposed circuit can operate up to several kHz and have high reliability and longer life than conventional ones. In also gives voltage balance of IBGTs automatically. So, the difference of characteristics of IGBTs and drive signal does not cause severe problems. To verify the proposed circuit, 20kV and 300A pulse generator is manufactured and tested.
Acute Renal Failure after Large Doses of Intravenous Immune Globulin (1999)

Large doses of Sandoglobulin (400-2000 mg/kg) have been associated with acute renal failure due to the large sucrose load. By taking certain precautions, especially in high-risk patients, this uncommon, but serious, adverse effect can be avoided.
Protoplasm: Endoplasmic Reticulum and Microsomes and Their Properties (1963)

Macrophage polarization refers to how macrophages have been activated at a given point in space and time. Polarization is not fixed, as macrophages are sufficiently plastic to integrate multiple signals, such as those from microbes, damaged tissues, and ...Read More
A review on plant growth promoting rhizobacteria acting as bioinoculants and their biological approach towards the production of sustainable agriculture (2015)

Plant growth promoting rhizobacteria are the soil bacteria inhabiting around/on the root surface and are directly or indirectly involved in promoting plant growth and development via production and secretion of various regulatory chemicals in the vicinity of rhizosphere. There has been much research interest in PGPB and there is now an increasing number of PGPB being commercialized for various crops. Today a lot of efforts have been made for searching and investigating the PGPB and their mode of action, so that they can be exploited commercially as biofertilizers. Because of the various challenges faced in screening, formulation, and application, PGPB have yet to fulfill their promise and potential as commercial inoculants. Recent progress in our understanding of their diversity, colonization ability, mechanisms of action, formulation, and application should facilitate their development as reliablecomponents in the management of sustainable agricultural systems. Several reviews have discussed specific aspects of PGPB as bioinoculants. We have tried to critically evaluate the current status of bacterial inoculants for contemporary agriculture in developed and developing countries. This review focuses on some important information regarding the biofertilizing potential of some important group of microbes, their formulations, their application for the development of sustainable technology, scope of improvement by genetic engineering, steps to be undertaken for their commercialization and their future prospects.
Visual syntax diagrams for programming language statements (1990)

article Free Access Share on Visual syntax diagrams for programming language statements Author: Lisa M. Braz Informix Software, Inc. Informix Software, Inc.View Profile Authors Info & Claims ACM SIGDOC Asterisk Journal of Computer DocumentationVolume 14Issue 41990 pp 23–27https://doi.org/10.1145/97435.97987Published:01 September 1990Publication History 12citation941DownloadsMetricsTotal Citations12Total Downloads941Last 12 Months61Last 6 weeks11 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteeReaderPDF
NF-E2-related factor 2 and its role in diabetic nephropathy. (2013)

Diabetic nephropathy is the leading cause of chronic kidney disease and end-stage renal disease. Oxidative stress has been recognized as a major contributor to its pathogenesis. Defensive mechanisms have also widely been studied. One of them, the NF-E2-Related Factor 2, is reviewed in this article.
Development of students’ speech (2016)

Consideration of this issue in the article is defined with goals and objectives of teaching the practical disciplines «Professionally-oriented Russian language» and «Culture of speech and language communication» in Kazakh groups. It is required to improve the methodological techniques, to develop and consolidate students’ skills in oral public speech, the need to train them properly to make the selection of materials for speech, reports, research papers, participate in problematic discussions, speak to the audience, to acquaint with the peculiarities of public speeches and presentations, master the technique of speech, oratorical skill and culture of speech.
Wire Adhesion Testing (1972)

Abstract The results of this study are conclusive. The ASTM D-2229 Test Method is not a reliable test for measuring adhesion of wire cords to rubber compounds. However, by using the basic design and modifying it, an accurate measurement of bond strength on a macroscopic level can be obtained. This test is insensitive for all practical purposes to compound physical properties and changes in cord diameter and embedded length—for both stranded and rod-like cords. It is also possible with this test to calculate the amount of stress that is exerted on the surface of the wire cord to determine the relationship between failing stress and the material strength of the rubber compound. Properly used, this new test should give the compounder a better tool to study the adhesion of compounds to metal.