gebhart/patrepeval huggingface dataset:
Surgical treatment of thyrotropin-secreting pituitary adenomas (1990)

Thyrotropin-secreting pituitary adenomas have been diagnosed more frequently as radiographic techniques and biochemical assays have improved; however, they remain uncommon and are unfamiliar to most neurosurgeons. This report concerns eight patients with hyperthyroidism, inappropriately elevated levels of serum thyrotropin and alpha-subunit, and radiographic evidence of pituitary tumor. All underwent surgery and had pathological confirmation of a thyrotropin-secreting adenoma, and most had been subjected to prior ablation of the thyroid gland. Only one tumor was a microadenoma; the others ranged in size from 1.4 to 12 cm, and invasion of parasellar structures was common. Thyrotropin, triiodothyronine, thyroxine, and alpha-subunit were measured preoperatively and at intervals postoperatively. Coexistent hormonal abnormalities (which occurred in all patients) included acromegaly and hyperprolactinemia and were also monitored. All four patients who had tumors less than 2 cm in diameter remain alive. Complete extirpation of tumor in these patients produced rapid correction of all hormonal abnormalities and resolution of clinical hyperthyroidism. The other four patients had larger invasive tumors: two died soon after surgery, one died of disseminated tumor 8 years after presentation, and one remains alive with residual tumor. Tumors secreting thyroid-stimulating hormone are less easily cured by surgery than are other types of pituitary adenoma because of the large size and invasive features that many attain during the delay to diagnosis; medical therapy can subdue the tumor but not cure it. The experience with these patients establishes the importance of early diagnosis and surgical excision for successful treatment, and demonstrates the utility of modern diagnostic techniques for finding these lesions. As occurs in Nelson's syndrome after adrenalectomy for Cushing's disease, ablation of the target organ may allow the tumor to convert to a more clinically malignant form which is resistant to cure.
Secure Resource Sharing in Ad Hoc Networks (2008)

Mobile and wireless devices become more popular and their capabilities increase as well. At the same time, most of the today’s PC power is unused, as a study of the Gartner Group indicates. Grid computing and P2P systems take advantage of this fact and provide unused resources to other nodes within the network, but mobile scenarios or ad hoc networks are often left out. This paper presents a concept for secure resource sharing in mobile ad hoc networks, with a special focus on challenges and problems with mostly unknown and potentially unreliable and untrustworthy devices. Virtualization technologies will be presented as a solution to grant application security, as they are also used in grid and trusted computing. The secure resource sharing (SRS) system, that will be presented in this paper as well, focuses on granting security aspects like availability, privacy, confidentiality and trust establishment in the area of resource sharing.
Lifestyle Recommendations for Dementia Prevention: PASCAL (2009)

Department of Preventive Medicine & Public Health, Ajou University School of Medicine, Suwon, Korea Institute on Aging, Ajou University Medical Center, Suwon, Korea Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea Department of Social and Preventive Medicine, Sungkyunkwan University School of Medicine, Suwon, Korea Department of Psychiatry and Behavioral Sciences, Ajou University School of Medicine, Suwon, Korea
A practical protocol for quantum networking with semiconductor quantum dots (2008)

A protocol is presented for generating entanglement between spatially separated quantum dots with different emission wavelengths and radiative lifetimes. This protocol can be practically implemented in semiconductor systems where emitters suffer from large inhomogeneous broadening.
The Hemorrhagic Synchorne Complicating Extracorporeal Shunting of Blood: An Experimental Study of its Pathogenesis (1958)

Summary Dogs subjected to extracorporeal circulation with a modified D e Wall heart-lung apparatus developed thrombocytopenia and severe deficiency of the antihemophilic factor (AHF). To quantitate this reaction more accurately, a two-stage method of study was devised whereby citrated blood in the first stage was subjected to artificial, oxygenation and then in the second stage, was transfused into recipient dogs. In all cases, depression in AHF and platelets occurred even though fibrinogen remained at high levels. Depression in AHF levels could also be produced by mechanical damage to tissues of the extremities or by the autotransfusion of stored blood. Control transfusion of fresh blood produced no such effects.
Progress and future of in vitro models to study translocation of nanoparticles (2015)

The increasing use of nanoparticles in products likely results in increased exposure of both workers and consumers. Because of their small size, there are concerns that nanoparticles unintentionally cross the barriers of the human body. Several in vivo rodent studies show that, dependent on the exposure route, time, and concentration, and their characteristics, nanoparticles can cross the lung, gut, skin, and placental barrier. This review aims to evaluate the performance of in vitro models that mimic the barriers of the human body, with a focus on the lung, gut, skin, and placental barrier. For these barriers, in vitro models of varying complexity are available, ranging from single-cell-type monolayer to multi-cell (3D) models. Only a few studies are available that allow comparison of the in vitro translocation to in vivo data. This situation could change since the availability of analytical detection techniques is no longer a limiting factor for this comparison. We conclude that to further develop in vitro models to be used in risk assessment, the current strategy to improve the models to more closely mimic the human situation by using co-cultures of different cell types and microfluidic approaches to better control the tissue microenvironments are essential. At the current state of the art, the in vitro models do not yet allow prediction of absolute transfer rates but they do support the definition of relative transfer rates and can thus help to reduce animal testing by setting priorities for subsequent in vivo testing.
Design of planar fork power dividers using microwave CAD (2003)

The design of L-band planar fork power dividers using commercially available software tool HP-EEsof Series IV is presented, HP-EESof is able to accurately model and optimise multi-port microstrip circuits that include junctions of no more than four microstrip lines. For a larger number of lines forming junctions the wiring facility of HP-EESof is used. Such circuits when developed require experimental tuning. This approach is demonstrated in the design and development of 6-way, single- and double-stage, and 12-way double-stage fork dividers.
Intensity fluctuation spectroscopy of deoxyribonucleic acid (DNA). I. Temperature profile of bacteriophage N1‐DNA (1977)

Abstract Intensity‐fluctuation laser‐light‐scattering spectroscopy has been used to characterize the temperature dependence of the translational diffusion coefficient through the helix–coil region for the DNA isolated from bacteriophage N1. The diffusion coefficient does not change smoothly, but exhibits fine structure detail similar to that seen in the uv absorption hyperchromicity. These changes are related to the heterogeneous distribution of bases along the N1‐DNA chain.
Decarboxylierung der Aminos&auml;uren. III (1964)

N-Methylphenethylamine was obtained by the decarboxylation of N-carboxymethyl-L-phenylalanine or N-methyl-L-phenylalanine. Decarboxylation of N-carboxymethyl-L-leucine or N-methyl-L-leucine gave N-methylisopentylamime. N-Methyltyramine obtained by the decarboxylation of N-carboxymethyltyramine was identical with that obtained by Goldschmidt from N-methyl-L-tyrosine.
Immune Response Changes with Blood Pump Use in Calves (1989)

Device-related bacterial infections are a significant deterrent to the long-term implantation of the total artificial heart (TAH). Device-related infections in the calf are caused by the same spectrum of organisms, over approximately the same time course, as those reported in man. We studied immunologic function in two groups of 3-4 month old, Holstein steer calves; four animals underwent cardiopulmonary bypass (CPB) only and seven calves underwent CPB and TAH implantation. There was a transient rise in total white blood cell counts and a transient fall in the hematocrit following the procedures in each group. Absolute numbers of neutrophils in the TAH group declined to near or below preoperative levels by the end of the 1 month study period. There was a transient increase in chemotactic response of isolated neutrophils to bovine C5a immediately following CPB and increased hydrogen peroxide production on postoperative day 3. Hydrogen peroxide levels were elevated in the TAH animals from postoperative day 14 to the end of the study period. Serum immunoglobulin levels of IgG, IgM, and IgA did not change significantly during the study period in the TAH group. IgG levels were elevated after week 3 in the CPB group.
Immunohistochemical Analysis of Interleukin-1β–Converting Enzyme/Ced-3 Family Protease, CPP32/Yama/Caspase-3, in Hodgkin's Disease (1997)

The Caenorhabditis elegans cell death gene, Ced-3, encodes a protein homologous to mammalian interleukin-1β–converting enzyme (ICE), a cysteine protease implicated in programmed cell death (PCD). CPP32, also known as Yama, apopain, and Caspase-3, is a member of this family, has substrate specificities similar to Ced-3, and has been shown to have an active role in PCD. Evidence suggests that these proteases act downstream of inhibitors of PCD such as Bcl-2 and Bcl-xL , which are frequently expressed in Reed-Sternberg (RS) cells of Hodgkin's disease (HD). To date there have been no studies examining the role of the ICE/Ced-3 family of proteins, in particular CPP32, in HD. We examined 24 cases of HD with a classical immunophenotype and 6 cases of nodular lymphocyte predominant HD (NLPHD) for the expression of CPP32 in the RS cells and lymphohistiocytic (L&H) cells as detected by immunohistochemistry. Twenty two of 24 cases (92%) of HD expressed the protein in the RS cells, whereas the L&H cells in all 6 cases of NLPHD lacked expression of CPP32. These results provide further evidence that NLPHD is a phenotypically different disease distinct from classical forms of HD. The differential expression of the cell death protein CPP32 may be an important factor contributing to the apparently different clinical behaviour of NLPHD in contrast to classical HD. The lack of expression of CPP32 in NLPHD shares similarities with low-grade B-cell non-Hodgkin's lymphomas and may explain their common clinical course. Further studies are required to elucidate the significance of CPP32 in HD.
Knowledge modeling environment for job-shop scheduling problem (2002)

The scheduling model and method must be designed to be application-domain dependent so as to reflect a set of constraints, objectives and preferences which reside in the target problem. We analyzed the scheduling process of human experts in a knowledge-base level and have developed a task-specific shell named ARES/SCH. ARES/SCH possesses a primitive task library that is a collection of domain-independent and generic components of scheduling mechanisms. The whole scheduling method can be described as a combinational flow-chart of primitive tasks. Memory module mounting shop (MMS) scheduling is shown as an example of ARES/SCH applications. It was apparent that ARES/SCH contributes to the rapid development of scheduling systems and supports a wide range of scheduling domains.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Chemical Quality and Production of Agars Extracted from Gracilaria tikvahiae Grown in Different Nitrogen Enrichment Conditions (1981)

Article Chemical Quality and Production of Agars Extracted from Gracilaria tikvahiae Grown in Different Nitrogen Enrichment Conditions was published on January 1, 1981 in the journal Botanica Marina (volume 24, issue 8).
310 DETERMINATION OF THE PORCINE OVIDUCTAL GLYCOSIDASES DURING THE ESTROUS CYCLE (2006)

Carbohydrates play a key role in different reproductive events, such as the sperm–oviductal cell interaction and sperm–oocyte recognition. For example, ß-d-galactose and a-d-mannose residues contained in the zona pellucida have been identified as sperm receptors in porcine oocytes (Song et al. 1999 J. Mamm. Ova Res. 16). The glycosidases, enzymes that remove carbohydrates, could play an important role in the reproductive tract, modulating decisive physiological events mediated by carbohydrates. However, the enzymatic activity level of these enzymes or their fluctuations throughout the estrous cycle in the porcine oviductal fluid (POF) has not been studied. The objective of this work was to compare the enzymatic activity level of 7 glycosidases in the POF at different stages of the estrous cycle. Oviducts were collected from the abattoir and classified according to the macroscopic aspect of the genital tract (Grippo et al. 1995 J. Reprod. Fertil. 105, 57–64) as early follicular please (presence of growing follicles), late follicular phase (presence of several grown follicles), early luteal phase (ovaries showing corpora hemorrhagica or recent corpora lutea), and late luteal phase (old corpora lutea or corpora albicans). After classification, oviducts were dissected and oviductal fluid samples were collected by aspiration with an automatic pipette while applying manual pressure from the isthmus toward the ampulla. Samples (6 per group) were centrifuged (7000g, 10 min) and the supernatant was stored at -20°C until assay. Total activity levels were measured fluorimetrically at 450 nm with the corresponding substrate conjugated to 4-methylumbelliferyl for each enzyme (Abascal et al. 1998 Biochem. J. 333, 201–207) using a FLUOstar Galaxy fluorometer (BMG Lab Technologies, Offenburg, Germany). Enzymatic assays were done in duplicate for 4 h at 37°C, and the reactions were stopped by adding glycine–calcium carbonate buffer. Fluorescence was corrected for tissue and substrate blanks. Fluorescence results of each enzyme and oviduct phase were analyzed using a one-way ANOVA with estrous cycle phase being the main factor. Results (mean counts of fluorescence, see Table 1) showed that changes of enzymatic activity during the estrous cycle and activity of some enzymes were modified during or after ovulation, suggesting a role of some glycosidases in the fertilization process. Preliminary assays for neuraminidase were negative in all samples. Future studies are necessary to identify the biological role played by the glycosidases present in the POF. Table 1. Changes in porcine oviductal glycosidases during the estrous cycle Supported by Fundacion Seneca (03018/PI/05) and Ministerio de Educacío y Ciencia (Project code 3495).
PSIKOLOGI PEMBANGUNAN KANAK-KANAK: PERKAITAN ANTARA PSIKOLOGI PENDIDIKAN BARAT DAN PSIKOLOGI PENDIDIKAN ISLAM Psychology of Child Development: Relations of Western Educational Psychology and Islamic Educational Psychology (2019)

This article discussed on the relations between the theories of child psychology development proposed by western psychologist and the teachings of Islamic concepts in child education. Western theories were saw as the ideal concept in child psychology as it was based on the scientific and observation. However, both concepts coming from western and Islamic teachings are parallel to one another in terms of practicality, which rarely being discussed. As to that, this article was written to enlighten the clear bridge between western ad Islamic teaching in child psychology.
User interface guidelines and standards: progress, issues, and prospects (1999)

This article reviews progress in the development of standards and guidelines for human–computer interaction, including those developed within international and US standards bodies. Guidance for incorporating software ergonomics standards and guidelines into software design and development processes is discussed. Several different techniques that have been defined for assessing the conformance of a product to guidelines are reviewed. In addition, the strategies employed by formally approved standards developed in ISO and ANSI for determining conformance are discussed. Finally, we discuss the prospects and challenges for software ergonomics standards and guidelines that must be addressed as the pace of technological change continues to accelerate.
Penicillin Allergy and the Relevance of Epicutaneous Tests (1985)

Epicutaneous tests with penicillins are important in the evaluation of penicillin allergy in patients who have shown a delayed urticarial or maculo-papular rash after the administration of penicillin derivatives. Of 23 patients who showed positive epicutaneous tests only 5 also showed immediate-type reactivity upon subsequent intracutaneous tests with the major determinant of penicillin. Moreover, patients with positive epicutaneous tests were evidently immunologically reactive on penicillins, since lymphocytes from 14 out of 17 patients showed increased DNA synthesis induced by penicillin G and ampicillin in vitro. The performance of epicutaneous tests with various penicillin derivatives is recommended as a first step in establishing penicillin allergy, because it is a safe method and because an extra group of sensitized patients is detected.
[Pre-implant esthetic study]. (1990)

The first dental prostheses used on Branemark implants were aesthetically disappointing both for the dentists and their patients. Therefore the authors will consider the various aesthetic problems encountered when treating loss of teeth with implant systems. The problems related to resorption are numerous: large bone losses are resolved by adapting removable acrylic, carrying out bone transplants immediately fixed by the implants, using filling materials, or complete dentures fixed with attachments supported by the implants. Periodontal surgery often provides a solution to the problem of gum visibility at the level of the maxillary anterior teeth. The problems related to the site where implants emerge can often be avoided by consultation between the surgeon and the prosthodontist and by flexing a surgical guide compiled from a pre-prosthetic analysis of the clinical situation. The aesthetic problems related to the actual implant systems are dependent on three factors: When the prosthesis is directly screwed onto the implant, the axis of the implant determines the axis of the dental prosthesis and can lead to the emergence of the screw on the buccal surface; With angulated cores, orientated screws provide the required solution. The implant material, when metallic leads to an unsightly border at the gingival level. Ceramic implants, or the "ceraming" of titanium, provide a solution to this problem. In case of diastema the use of an implant system gives the best choice in comparison to the more conventional treatments. In conclusion, the authors point out the importance of pre-implant analysis which must give an evaluation of the aesthetic result. The fragility of the aesthetic evaluation should encourage dentists to obtain the "clear and written consent" of their patients, accepting the risks run by treatment of this kind.
“Stückelberg Interferometry” with Ultracold Molecules (2007)

We report on the realization of a time-domain "Stückelberg interferometer", which is based on the internal-state structure of ultracold Feshbach molecules. Two subsequent passages through a weak avoided crossing between two different orbital angular momentum states in combination with a variable hold time lead to high-contrast population oscillations. This allows for a precise determination of the energy difference between the two molecular states. We demonstrate a high degree of control over the interferometer dynamics. The interferometric scheme provides new possibilities for precision measurements with ultracold molecules.
Differences in the effects of angiotensin converting enzyme inhibitors with or without a thiol group in chronic renal failure in rats (1989)

1. We have investigated the effects of the non-renin-mediated actions of angiotensin converting enzyme inhibitors on the progression of chronic renal failure accelerated by hypertension. For this purpose, we studied the effects of captopril (a thiol-containing angiotensin converting enzyme inhibitor), enalapril (an angiotensin converting enzyme inhibitor without a thiol group) and cysteine (a thiol-containing amino acid which has no angiotensin converting enzyme-inhibitory action) in adriamycin-treated rats with deoxycorticosterone acetate-salt hypertension, in which the renin-angiotensin system was suppressed. 2. There were no significant differences in blood pressure between these groups and the control group [adriamycin-treated group with deoxycorticosterone acetate-salt loading, 206 +/- 7 mmHg (27.4 +/- 0.9 kPa) at week 10]. 3. Massive proteinuria occurred in all groups. At the end of the experiment (at week 10), urinary protein excretion was significantly reduced in the captopril and cysteine groups compared with the control group. No manifest improvements appeared in the enalapril group. 4. Levels of serum creatinine and blood urea nitrogen increased progressively. At week 10, the increases in the serum levels of creatinine were less in the captopril (87 +/- 16 mmol/l) and cysteine (80 +/- 19 mmol/l) groups than in the control group (124 +/- 27 mmol/l) (P less than 0.01). No marked differences were found between the control and enalapril groups. 5. Captopril and cysteine caused more than a three-fold reduction in the focal glomerulosclerosis score when compared with that in the control group, but enalapril did not decrease the score. The extent of tubulointerstitial change was parallel with the focal glomerulosclerosis score. 6. We conclude that the thiol group is possibly involved in the mechanism of the beneficial effects of some angiotensin converting enzyme inhibitors on the progression of chronic renal failure exacerbated by hypertension.
Détermination expérimentale de quelques caractéristiques optiques d'un système double prisme magnétique-miroir électrostatique (1972)

Nous avons mis au point une méthode pratique pour étudier expérimentalement les propriétés optiques du premier ordre (focalisation) dans la première traversée de l'aimant du microanalyseur ionique (constitué par un double prisme magnétique à champ uniforme associé à un miroir électrostatique). On détermine ainsi le point stigmatique réel du prisme à quelques dixièmes de millimètre près. Le dispositif utilisé est assez précis pour qu'on puisse mesurer les aberrations d'ouverture du second ordre au cross-over intermédiaire. Par ailleurs, en étudiant expérimentalement le miroir avec l'analyseur complet, nous localisons le centre du miroir convexe équivalent à quelques dixièmes de millimètre près également, ainsi que son sommet, et nous mettons en évidence l'influence de l'énergie des particules sur la position du centre du miroir. Ceci permet d'obtenir une meilleure résolution en masse et d'améliorer la qualité des images de distribution données par l'analyseur.