gebhart/patrepeval huggingface dataset:
The plasma membrane H<sup>+</sup>‐ATPase from maize roots is phosphorylated in the C‐terminal domain by a calcium‐dependent protein kinase (1998)

A protein kinase activity associated with maize root plasma membranes was partially purified and characterized. Biochemical properties, such as calcium dependence, inhibition by calmodulin antagonists, and absence of calmodulin stimulation, indicated that the enzyme belongs to the calcium‐dependent protein kinase (CDPK) family. By means of an in‐gel phosphorylation assay the molecular mass of active polypeptides was determined: two bands of 55 and 51 kDa became labelled. The same proteins were also immunodecorated by monoclonal antibodies against soybean CDPK. Results from in vitro assays demonstrated that maize H + ‐ATPase was a suitable substrate for this protein kinase and that the phosphorylation site was located at the C‐terminal domain of the enzyme. This result was confirmed by using as substrate in phosphorylation assays the isolated C‐terminal domain of the H + ‐ATPase expressed in Escherichia coli as a glutathione‐transferase fusion protein.
Elevated CO <sub>2</sub> selectively inhibits interleukin‐6 and tumor necrosis factor expression and decreases phagocytosis in the macrophage (2010)

Elevated blood and tissue CO(2), or hypercapnia, is common in severe lung disease. Patients with hypercapnia often develop lung infections and have an increased risk of death following pneumonia. To explore whether hypercapnia interferes with host defense, we studied the effects of elevated P(CO2) on macrophage innate immune responses. In differentiated human THP-1 macrophages and human and mouse alveolar macrophages stimulated with lipopolysaccharide (LPS) and other Toll-like receptor ligands, hypercapnia inhibited expression of tumor necrosis factor and interleukin (IL)-6, nuclear factor (NF)-kappaB-dependent cytokines critical for antimicrobial host defense. Inhibition of IL-6 expression by hypercapnia was concentration dependent, rapid, reversible, and independent of extracellular and intracellular acidosis. In contrast, hypercapnia did not down-regulate IL-10 or interferon-beta, which do not require NF-kappaB. Notably, hypercapnia did not affect LPS-induced degradation of IkappaB alpha, nuclear translocation of RelA/p65, or activation of mitogen-activated protein kinases, but it did block IL-6 promoter-driven luciferase activity in mouse RAW 264.7 macrophages. Elevated P(CO2) also decreased phagocytosis of opsonized polystyrene beads and heat-killed bacteria in THP-1 and human alveolar macrophages. By interfering with essential innate immune functions in the macrophage, hypercapnia may cause a previously unrecognized defect in resistance to pulmonary infection in patients with advanced lung disease.
ChemInform Abstract: Pictet‐Spengler Reactions in Aprotic Media. The Total Synthesis of (.+‐.) Suaveoline. (1992)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
New stability theorems for averaging and their application to the convergence analysis of adaptive identification and control schemes (1985)

We develop new stability theorems for the convergence analysis of a class of one and two-time scale time-varying nonlinear systems using averaging theory. These theorems are applied to a class of continuous time adaptive identifiers and model reference adaptive controllers to obtain estimates of the parameter rate of exponential convergence.
Polyazide Chemistry: Preparation and Characterization of Te(N<sub>3</sub>)<sub>4</sub> and [P(C<sub>6</sub>H<sub>5</sub>)<sub>4</sub>]<sub>2</sub> [Te(N<sub>3</sub>)<sub>6</sub>] and Evidence for [N(CH<sub>3</sub>)<sub>4</sub>][Te(N<sub>3</sub>)<sub>5</sub>]. (2004)

Abstract For Abstract see ChemInform Abstract in Full Text.
A Multilayer Data Copy Scheme for Low Cost Test with Controlled Scan-In Power for Multiple Scan Chain Designs (2006)

The random-like filling strategy pursuing high compression for scan test introduces large test power. To pursue high compression in conjunction with reducing test power for multiple scan chain designs is even harder and very few works were dedicated to solve this problem. This paper proposes and demonstrates a multilayer data copy (MDC) scheme for test compression as well as test power reduction for multiple scan designs. The scheme utilizes a buffer, which supports fast load using previous loaded data, to achieve test data compression and test power reduction at the same time. The scheme can be applied ATPG-independently or to be incorporated in an ATPG to generate highly compressible and power efficient test sets. Experiment results on benchmarks show that test sets generated by the scheme had large compression and power saving with little area design overhead
Theta pinch discharge designed for emission spectrochemical analysis: spectral characterization (1986)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTTheta pinch discharge designed for emission spectrochemical analysis: spectral characterizationGregory J. Kamla and Alexander. ScheelineCite this: Anal. Chem. 1986, 58, 4, 932–939Publication Date (Print):April 1, 1986Publication History Published online1 May 2002Published inissue 1 April 1986https://pubs.acs.org/doi/10.1021/ac00295a059https://doi.org/10.1021/ac00295a059research-articleACS PublicationsRequest reuse permissionsArticle Views67Altmetric-Citations14LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Selenium fortification of infant formulas: does selenium form matter? (2017)

Selenium is a trace element essential for the health and development of the growing infant. It is a necessary component of proteins and enzymes required for a variety of functions, including antioxidant defense, modulation of the inflammatory response, and production of thyroid hormones. In breast-fed infants, selenium stores depend on the selenium content of the mother's diet. In formula-fed infants, selenium levels are correlated to the residual selenium stores accumulated in utero and the level and type of selenium fortification used in the formula. Today, the United States Food and Drug Administration (FDA) recommends that infant formulas contain selenium at levels between 2.0 and 7.0 μg per 100 kcal. While the US FDA does not recommend a particular selenium form for fortification, evidence indicates that organically bound selenium forms (e.g., selenomethionine and selenium-enriched yeast) are better absorbed and retained than inorganic forms (e.g., selenite and selenate). Preliminary data from studies in adults do suggest that fortification with standardized selenium-enriched yeast may offer benefits compared to fortification with other organically bound selenium forms. However, because most studies evaluating the impact of selenium fortification of infant formula have assessed inorganic selenium supplements, additional research into the bioavailability and outcomes associated with the use of selenium-enriched yeast in infants is needed.
Orthogonal polarization fiber gyroscope with increased stability and resolution (1994)

The orthogonal polarization fiber gyroscope (OPFG) is an interferometric fiber gyroscope design that requires no phase bias in the fiber ring and is insensitive to light-source intensity noise. However, in the original OPFG [Hitachi Rev. 33, 215 (1984)], environmental changes caused first-order false rotation signals. We propose and experimentally verify modifications that eliminate the first-order sensitivity to environmental changes and that improve the gyroscope's resolution as well. We believe that this modified OPFG is the first interferometric fiber gyroscope capable of stable, high-sensitivity measurement that contains only reciprocal optical elements.
Developmental changes in rat sciatic nerve myelin (1981)

Conference Article| February 01 1981 Developmental changes in rat sciatic nerve myelin CHRISTOPHER LININGTON; CHRISTOPHER LININGTON 1Max-Planck-Institut für Experimentelle Medizin, Forschungsstelle Neurochemie, D-3400 Göttingen, Federal Republic of Germany Search for other works by this author on: This Site PubMed Google Scholar VOLKER NEUHOFF; VOLKER NEUHOFF 1Max-Planck-Institut für Experimentelle Medizin, Forschungsstelle Neurochemie, D-3400 Göttingen, Federal Republic of Germany Search for other works by this author on: This Site PubMed Google Scholar THOMAS V. WAEHNELDT THOMAS V. WAEHNELDT 1Max-Planck-Institut für Experimentelle Medizin, Forschungsstelle Neurochemie, D-3400 Göttingen, Federal Republic of Germany Search for other works by this author on: This Site PubMed Google Scholar Biochem Soc Trans (1981) 9 (1): 114–115. https://doi.org/10.1042/bst0090114 Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter LinkedIn Cite Icon Cite Get Permissions Citation CHRISTOPHER LININGTON, VOLKER NEUHOFF, THOMAS V. WAEHNELDT; Developmental changes in rat sciatic nerve myelin. Biochem Soc Trans 1 February 1981; 9 (1): 114–115. doi: https://doi.org/10.1042/bst0090114 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu nav search search input Search input auto suggest search filter All ContentAll JournalsBiochemical Society Transactions Search Advanced Search This content is only available as a PDF. © 1981 Biochemical Society1981 Article PDF first page preview Close Modal You do not currently have access to this content.
Proteomic profiling and pathway analysis of the response of rat renal proximal convoluted tubules to metabolic acidosis (2013)

Metabolic acidosis is a relatively common pathological condition that is defined as a decrease in blood pH and bicarbonate concentration. The renal proximal convoluted tubule responds to this condition by increasing the extraction of plasma glutamine and activating ammoniagenesis and gluconeogenesis. The combined processes increase the excretion of acid and produce bicarbonate ions that are added to the blood to partially restore acid-base homeostasis. Only a few cytosolic proteins, such as phosphoenolpyruvate carboxykinase, have been determined to play a role in the renal response to metabolic acidosis. Therefore, further analysis was performed to better characterize the response of the cytosolic proteome. Proximal convoluted tubule cells were isolated from rat kidney cortex at various times after onset of acidosis and fractionated to separate the soluble cytosolic proteins from the remainder of the cellular components. The cytosolic proteins were analyzed using two-dimensional liquid chromatography and tandem mass spectrometry (MS/MS). Spectral counting along with average MS/MS total ion current were used to quantify temporal changes in relative protein abundance. In all, 461 proteins were confidently identified, of which 24 exhibited statistically significant changes in abundance. To validate these techniques, several of the observed abundance changes were confirmed by Western blotting. Data from the cytosolic fractions were then combined with previous proteomic data, and pathway analyses were performed to identify the primary pathways that are activated or inhibited in the proximal convoluted tubule during the onset of metabolic acidosis.
Charge transfer dynamics of 3,4,9,10-perylene-tetracarboxylic-dianhydride molecules on Au(111) probed by resonant photoemission spectroscopy (2011)

Charge transfer dynamics across the lying-down 3,4,9,10-perylene-tetracarboxylic-dianhydride (PTCDA) organic semiconductor molecules on Au(111) interface has been investigated using the core-hole clock implementation of resonant photoemission spectroscopy. It is found that the charge transfer time scale at the PTCDA∕Au(111) interface is much larger than the C 1s core-hole lifetime of 6 fs, indicating weak electronic coupling between PTCDA and the gold substrate due to the absence of chemical reaction and∕or bonding.
ChemInform Abstract: Mild Rhodium(III)‐Catalyzed C—H Activation and Intermolecular Annulation with Allenes. (2013)

Abstract The novel oxidative coupling reaction of N‐pivaloyloxybenzamides or heterocyclic analogues with allenes affords a variety of dihydroisoquinoline derivatives.
Aphthous Lesions in Nodular Lymphoma of the Colon (1986)

The umbilicated nodules in colonic lymphoma may simulate aphthous ulcers of inflammatory or infectious colitides. Our report illustrates that in an immunosuppressed patient it may be difficult to distinguish on double contrast barium enema between the aphthous ulcers of opportunistic colitis and the umbilications of nodular colonic lymphoma.
Evaluation of Performance, Non-Uniformity and Thermal Limits for Infrared LED Scene Projectors (2019)

As the light emitting diodes Infrared Scene Projectors are evolving, the need to evaluate the performance and non-uniformity is at it is all times highest. This paper will describe how the performance of these systems are measured and how the non-uniformity is measured and corrected.
<title>Sol-gel and microwave processing of PZT materials for sensor and actuator applications</title> (1994)

In this work, the preparation of PZT materials used for the fabrication of smart sensors and actuators is closely investigated. The sol-gel method is used for the processing of the PZT powder because of its potential for making fine, pure and homogeneous powders. Sol-gel is a chemical method that has the possibility of synthesizing a reproducible material. Microwave energy is used for the calcining of this powder and the sintering of the PZT samples. Its use for calcination has the advantage of reducing the total processing time and the soak temperature. In addition, the combination of sol-gel and microwave processing leads to smaller particles and a more uniform distribution of their sizes. Microwave sintering of sol-gel prepared PZT has been accomplished successfully and has been shown to yield improved microstructure and good properties.
Morphologie des particules : de la visualisation à la mesure (1998)

National audience
Potential and limitations of penumbral imaging (1986)

In this paper we describe a study of penumbral imaging which examines the SNR advantage of the technique as well as the influence of various factors that will affect the practical implementation of the technique. These include noise, errors, and uncertainties in the camera geometry and the three-dimensionality of the object. The technique is shown to be very tolerant of the errors that may reasonably be expected. The discussion is primarily in the context of the application of penumbral imaging to laser-produced plasma research.
Robust object extraction using normalized principal component features (2003)

A new general purpose method for object extraction and detection, RONPaC (Robust Object Extraction (Detection) using NPaC Features) method is presented. RONPaC employs normalized principal component (NPaC) features as a measure of similarity between corresponding regions of a target image and a background image. No a priori knowledge of objects and no assumptions about the environment are required. The object extraction problem is dealt with as a discriminant problem of two classes, 'object' and 'background', in the feature space. The performance of the method is quantitatively evaluated using various real images and compared with conventional methods using two criteria, separability between two classes in feature space and ease of binarizing expressed by the maximum discriminant criterion. Experimental results confirm the extraction accuracy and applicability of the proposed method.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Cytosolic location of an endo-<i>N</i>-acetyl-β-D-glucosaminidase activity in rat liver and kidney (1979)

Endo-N-acetyl-beta-D-glucosaminidase activity towards an oligomannosidic type glycoamino acid substrate was found in the soluble fraction of rat liver and kidney. No evidence for a lysosomal form of the activity was found.
Zoospore Homing and Infection Events: Effects of the Biocontrol Bacterium <i>Burkholderia cepacia</i> AMMDR1 on Two Oomycete Pathogens of Pea ( <i>Pisum sativum</i> L.) (2000)

Burkholderia cepacia AMMDR1 is a biocontrol agent that protects pea and sweet corn seeds from Pythium damping-off in field experiments. The goal of this work was to understand the effect of B. cepacia AMMDR1 on Pythium aphanidermatum and Aphanomyces euteiches zoospore homing events and on infection of pea seeds or roots. In vitro, B. cepacia AMMDR1 caused zoospore lysis, prevented cyst germination, and inhibited germ tube growth of both oomycetes. B. cepacia AMMDR1 also reduced the attractiveness of seed exudates to Pythium zoospores to nondetectable levels. However, when present at high levels on seeds, B. cepacia AMMDR1 had little net effect on zoospore attraction, probably because it also enhanced seed exudation. Seed-applied B. cepacia AMMDR1 dramatically reduced the incidence of infection by Pythium zoospores in situ compared with an antibiosis-deficient Tn5 mutant strain. This mutant strain also decreased Pythium infection incidence to some extent, but only when the pathogen inoculum potential was low. B. cepacia AMMDR1 did not affect attraction of Aphanomyces zoospores or Aphanomyces root rot incidence. These results suggest that B. cepacia AMMDR1 controls P. aphanidermatum largely through antibiosis, but competition for zoospore-attracting compounds can contribute to the effect. Differences in suppression of Aphanomyces and Pythium are discussed in relation to differences in the ecology of the two pathogens.
Pyrolysed N{sub 4}-chelates: Novel electrocatalysts for chemical and biosensors (1996)

During the last few years the use of different types of N{sub 4}-metal chelates (especially phtalocyanines and phorphyrins) for electroanalytical and biosensor applications has been attracting increasing attention. Electroanalytical application of such catalysts is generally based on their use as electrode modifiers. The use of N{sub 4}-metal chelates offers several advantages: they show high catalytic activity combined with some analyte selectivity; they are suitable for forming thin layers over an inert electrode; they demonstrate compatibility with enzymes and different immobilization reagents; the electrode modification procedures can be arranged as a step in the sensor micromanufacturing procedure. Oxygen reduction as well as redox properties of numerous organic compounds have been studied on electrodes modified with N{sub 4}-metal chelates. Some of the N{sub 4}-metal chelates have been employed as catalysts for oxygen electroreduction and the electrochemical oxidation of hydrogen peroxide. During the work described, catalysts were prepared by deposition of CoTMPP or H{sub 2} TMPP on non-carbon dispersed carrier, followed by the pyrolysis of the compound and by removal of the carrier. Both pyrolysis products possess high electrocatalytic activity for oxygen reduction and hydrogen peroxide reduction and oxidation.
Subversion Mechanisms by Which<i>Leishmania</i>Parasites Can Escape the Host Immune Response: a Signaling Point of View (2005)

The obligate intracellular parasite Leishmania must survive the antimicrobial activities of its host cell, the macrophage, and prevent activation of an effective immune response. In order to do this, it has developed numerous highly successful strategies for manipulating activities, including antigen presentation, nitric oxide and oxygen radical generation, and cytokine production. This is generally the result of interactions between Leishmania cell surface molecules, particularly gp63 and LPG, and less well identified macrophage surface receptors, causing the distortion of specific intracellular signaling cascades. We describe some of the signaling pathways and intermediates that are repressed in infected cells, including JAK/STAT, Ca(2+)-dependent protein kinase C (PKC) isoforms, and mitogen-activated protein kinases (especially ERK1/2), and proteasome-mediated transcription factor degradation. We also discuss protein tyrosine phosphatases (particularly SHP-1), intracellular Ca2+, Ca(2+)-independent PKC, ceramide, and the suppressors of cytokine signaling family of repressors, which are all reported to be activated following infection, and the role of parasite-secreted cysteine proteases.
Repair of ultraviolet-light-induced damage (1981)

Studies are reviewed which present three major new findings in the photobiology of skin. First, detectable numbers of dimers are formed even at sub-erythymal doses. Second, excision of dimers is much more rapid than would be predicted from results obtained in cell culture. Third, comparison of the rates of excision and photoreactivation in skin indicates that in normal sunlight exposure, photoreactivation may well be the predominant repair pathway in skin. (ACR)
Co-Digestion of Cattle Slurry and Waste Milk under Shock Loading Conditions (1997)

Anaerobic digestion of cattle slurry has become a well established practice. In recent years disposal of waste milk in the UK has been the cause of many pollution incidents. This paper describes the co-digestion of cattle slurry and waste milk under shock loading conditions in 1 dm3 laboratory digesters. Methane concentration in the biogas of all digesters receiving waste milk additions initially dropped, but quickly recovered to above previous levels. The methane production rate (dm3 methane day−1) was most elevated in those digesters receiving the greatest loading of waste milk; however, initial depression of biogas methane concentration was also greatest in this system. © 1997 SCI.
Familial Dandy‐Walker malformation associated with macrocephaly, facial anomalies, developmental delay, and brain stem dysgenesis: Prenatal diagnosis and postnatal outcome in brothers. A new syndrome? (1994)

Brothers are reported with an apparently new constellation of manifestations including Dandy-Walker complex (DWC), migrational brain disorder, macrocephaly, and facial anomalies. The first brother presented at birth, the second was detected prenatally with DWC and the pregnancy terminated. Fetal brain histopathology showed DWC associated with brainstem dysgenesis. Inheritance is likely autosomal or X-linked recessive. An extensive review of the differential diagnosis of DWC is provided.