gebhart/patrepeval huggingface dataset:
Combustion of HTPB Based Solid Fuels Containing Metals and Metal Hydrides with Nitrous Oxide (2019)

Abstract An experimental investigation of the combustion characteristics of HTPB‐based solid fuels containing aluminum and aluminum hydride has been conducted. Aluminum is commonly used as a fuel supplement in solid rocket propellants because of its ability to increase the specific impulse of a propellant. Similarly, aluminum hydride, or alane, is another attractive fuel supplement because it can significantly (∼7–8 %) increase specific impulse even beyond that of aluminum. In this study, the regression rates of a baseline fuel (pure HTPB) were compared with that of fuels containing either aluminum or alane as additives using a counterflow combustion experiment with nitrous oxide (N 2 O) as the oxidizer. The additives were investigated in concentrations of 10, 20, and 40 % by weight of the fuels. The addition of aluminum at all loadings resullted in a decrease in the regression rate relative to the baseline, whereas the addition of alane resulted in at worst similar regression rates and at best (highest loading) approximately a 20 % increase in regression rate. The decomposition behavior of selected fuels was analyzed using traditional thermal analysis techniques; thermal gravimetric analysis and differential scanning calorimetry
Diffusion Thermopower of<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mo stretchy="false">(</mml:mo><mml:mi>Ga</mml:mi><mml:mo>,</mml:mo><mml:mi>Mn</mml:mi><mml:mo stretchy="false">)</mml:mo><mml:mi>As</mml:mi><mml:mo>/</mml:mo><mml:mi>GaAs</mml:mi></mml:math>Tunnel Junctions (2011)

We report the observation of tunneling anisotropic magnetothermopower, a voltage response to a temperature difference across an interface between a normal and a magnetic semiconductor. The resulting voltage is related to the energy derivative of the density of states in the magnetic material, and thus has a strongly anisotropic response to the direction of magnetization in the material. The effect will have relevance to the operation of semiconductor spintronic devices, and may indeed already play a role in correctly interpreting the details of some earlier spin injection studies.
Light-induced dark decays of photorefractive gratings and their observation in Bi12SiO20 (1989)

We find that the temporal shape and speed of dark decays of photorefractive gratings depend on the light intensity used to write the grating. We attribute this to the fact that the population distribution of impurity levels inside the crystal under illumination is light intensity dependent and differs from the thermal equilibrium distribution. We use a simple extension of the band conduction model of Kukhtarev which considers an additional shallow trap level to analyze dark decays observed in a Bi12SiO20 crystal. We find the excitation rate for thermally excited charge carriers and their diffusion length when this crystal is under illumination and obtain estimates for the shallow trap density (∼1.5×1015 cm−3) and the shallow trap occupation lifetime (∼0.2 s). We identify the shallow trap as a shallow hole trap by comparing the results from our dark decay analysis to results obtained from beam-coupling and light-induced erasure measurements.
Barbara Hammer- ART CART Oral Histories (2016)

The theme of the oral history is “Challenges: Youth and Age.” We focused on exploring the evolution of Barbara Hammer as she experiences life and new challenges. In her youth Barbara reflects on her upbringing and memories with her grandma. In her age, Barbara discusses her battle with ovarian cancer. She makes connections between her health condition and her art, and how the cancer has impacted her both as an individual and an artist. Hammer also discusses plans for the future and in terms of her career, personal life, and tackling new challenges. The oral history exemplifies Barbara Hammer’s positive attitude, courage, and resilience.
Optically controlled K-band oscillator (2002)

PIN photodiodes play an important role in detection of modulated light in fiberoptic links, however, these devices are essentially junction devices, with bias-dependent capacitance very similar to those of varactor diodes. Particularly under proper biasing conditions, junction capacitance of these devices can be changed by light illumination. Results are reported of tuning and frequency modulation experiments of a 24.5-GHz oscillator configured with a PIN photodiode as the tuning element. Both electrical and optical tuning were investigated, resulting in tuning range of few hundred megahertz at K-band.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Risk factors for treatment failure in smokers: Relationship to alcohol use and to lifetime history of an alcohol use disorder (2008)

Little is known about the impact of alcohol involvement on smoking cessation relapse or possible mechanisms for these associations. We addressed these issues using data from a randomized clinical trial of two types of framed messages (gain vs. loss) in conjunction with open label sustained-release (SR) bupropion (Toll et al., 2007) (N = 249). Participants were categorized according to whether or not they were diagnosed with a lifetime alcohol use disorder (AUD; i.e., current or past alcohol abuse or past alcohol dependence) and according to three levels of alcohol use: abstinence, moderate, or hazardous use. Alcohol use categories were established for drinking at baseline, during the 6-week treatment period and through 12 weeks post-quit. There were few significant differences by baseline alcohol use level or AUD history for a series of predictors of smoking cessation failure (e.g., depressive symptoms). During treatment and follow-up, the probability of any smoking on heavy drinking days was significantly higher than the probability of smoking on moderate drinking or abstinent days. AUD history did not predict smoking cessation relapse in any analysis, nor were any alcohol usexAUD history interactions significant. Moderate alcohol users and, to a lesser extent, abstainers from alcohol at baseline were less likely than hazardous drinkers to have relapsed at 12 weeks post-quit. Based on these findings, it appears that risk of any smoking and of relapse was associated primarily with heavy drinking days and a hazardous pattern of use respectively, rather than with moderate drinking.
Leveraging the DNA damage and transcriptional-regulatory roles of PARP-1 as a means to improve prostate cancer therapy. (2014)

179 Background: The first described roles for PARP-1 were in the repair of DNA damage and genomic maintenance, however, recent studies have identified PARP-1 as harboring critical context-dependent transcriptional regulatory functions. Our group recently discovered that PARP-1 enzymatic activity is a critical effector of androgen receptor (AR) function in models of prostatic adenocarcinoma (PCa), and is recruited to regulatory sites of select AR target genes. Pharmacological inhibition of PARP-1 enzymatic activity results in diminished AR and PARP-1 residency at AR target gene regulatory loci, reduced AR target gene expression (more than 50%), and reduced AR-driven, PCa-associated phenotypes, including castrate-resistant PCa (CRPC) AR function, tumor cell growth, and transition to CRPC. These data, in part, served as critical rationale for current clinical trials combining PARP inhibition and abiraterone for patients with metastatic CRPC NCT01576172 . Given the clinical importance of targeting AR function in PCa, preclinical studies were performed to assess the impact of leveraging the dual roles of PARP-1 as a means to improve therapy for advanced disease. Methods: In vitro and in vivo model systems were utilized to assess impact on AR and tumor growth. Multiple PARP inhibitors were used for additional studies. The impact of PARP-1 on gene expression was also assessed using unbiased analyses. PARP-1 mutants were also utilized to segregate the DNA damage and transcriptional regulatory roles of PARP-1. Results: Critically, PARP-1 inhibitors cooperated with castration to elicit an enhanced therapeutic response, and PARP-1 inhibitors were effective at suppressing CRPC growth in vivo. Multiple PARP inhibitors diminished AR chromatin occupancy, altered AR transcriptional output and reduction in PCa and CRPC cell growth. Conclusions: These data identify PARP-1 as a feasible therapeutic target for advanced prostate cancer. Multiple PARP inhibitors show pre-clinical efficacy in models of PCa and CRPC and merit consideration for clinical trial, and a concept will be presented.
Fisher Information with Continuous Variable Quantum Resources (2019)

Squeezed states of light are a crucial resource for improving the precision of parameter estimation [1], and this has made an impact in areas as wide ranging as biological imaging [2] and gravitational wave detection [3]. However, the optimal bounds of the Fisher information (FI) in continuous variable (CV) quantum metrology have, so far, only been abstractly defined and do not account for many important experimental parameters, such as the quantum efficiency and bandwidth of the detector [4]. We show that classical FI calculations can be used to compute these optimal bounds with more applicability to experimental measurement. This is demonstrated in the case of single parameter estimation of a modulated optical loss, using a bright amplitude squeezed state as a probe.
Intronic Sequences Flanking Alternatively Spliced Exons Are Conserved Between Human and Mouse (2003)

Comparison of the sequences of mouse and human genomes revealed a surprising number of nonexonic, nonexpressed conserved sequences, for which no function could be assigned. To study the possible correlation between these conserved intronic sequences and alternative splicing regulation, we developed a method to identify exons that are alternatively spliced in both human and mouse. We compiled two exon sets: one of alternatively spliced conserved exons and another of constitutively spliced conserved exons. We found that 77% of the conserved alternatively spliced exons were flanked on both sides by long conserved intronic sequences. In comparison, only 17% of the conserved constitutively spliced exons were flanked by such conserved intronic sequences. The average length of the conserved intronic sequences was 103 bases in the upstream intron and 94 bases in the downstream intron. The average identity levels in the immediately flanking intronic sequences were 88% and 80% for the upstream and downstream introns, respectively, higher than the conservation levels of 77% that were measured in promoter regions. Our results suggest that the function of many of the intronic sequence blocks that are conserved between human and mouse is the regulation of alternative splicing.
Trait Anger, Physical Aggression, and Violent Offending in Antisocial and Borderline Personality Disorders (2016)

Antisocial personality disorder (ASPD) and borderline personality disorder (BPD) are common conditions in forensic settings that present high rates of violence. Personality traits related to the five-factor model personality domains of neuroticism and agreeableness have shown a relationship with physical aggression in nonclinical and general psychiatric samples. The aim of the present investigation was to examine the association of these personality traits with violence and aggression in ASPD and BPD. Results revealed that trait anger/hostility predicted self-reported physical aggression in 47 ASPD and BPD subjects (β = 0.5, p = 0.03) and number of violent convictions in a subsample of the ASPD participants (β = 0.2, p = 0.009). These preliminary results suggest that high anger and hostility are associated with physical aggression in BPD and ASPD. Application of validated, self-report personality measures could provide useful and easily accessible information to supplement clinical risk assessment of violence in these conditions.
Multimodality optical imaging combining optical coherence tomography (OCT) and fluorescence lifetime imaging (FLIM) for morphological and biochemical tissue characterization (2010)

Here we report on our current efforts to simultaneously quantify both morphological and biochemical tissue information by combining optical coherence tomography (OCT) and fluorescence lifetime imaging (FLIM). The Fourier domain OCT module is built around a custom designed high-speed spectrometer (bandwidth of 102 nm, 3 dB rolloff of 1.2 mm, lines rates of up to 59 kHz). A 40 nm bandwidth SLED centered at 830 nm provided an axial resolution of 7.6 mm for OCT. The objective lens provided 10 um lateral resolution for OCT and 100 um for FLIM. Lateral OCT and FLIM beam scanning was accomplished using a set of galvo mirrors. The FLIM module excites and collects the fluorescence decay signal pixel by pixel coincident with OCT A-line collection. Each 2-D FLIM image has a corresponding coregistered OCT volume. Fluorescence excitation for FLIM was provided by a solid-state pulse laser (355 nm, 1 ns FWHM, 50 kHz rep rate). The fluorescence signal was detected with a MCP-PMT coupled to a 1.5 GHz digitizer (250 ps temporal resolutions). In addition, simultaneous multispectral time-resolved fluorescence detection was achieved by separating the fluorescence emission in three bands using a series of dichroic mirrors and bandpass filters, and launching each band into three fibers of different lengths (providing a time delay of 50 ns among bands) focused onto the MCP-PMT. The resulting OCT/FLIM system is capable of a maximum A-line rate of 59 kHz for OCT and a maximum pixel rate of at least 30 kHz for FLIM. The multimodality OCT/FLIM imaging system was validated on biological tissue. Future efforts include evaluating its potential for oral cancer diagnosis and intravascular imaging.
Damage Calculations for Devices in the Diagnostic Penetrations of a Fusion Reactor (1984)

Degradation of neutron-sensitive devices for fusion diagnostics is calculated as a function of location in ducts through bulk shields. It is shown that single-crystal semiconductor devices, such as n/p silicon diodes, will undergo severe degradation even at the rear of the shield. It will be necessary to replace devices at frequent intervals or withdraw semiconductor parts after a measurement. Device life can be extended by distance, elbows, shortening of exposure. hardening, or a combination thereof.
Psychological Predictors of Depression in Multiple Sclerosis (1995)

The aim of this study was to determine if learned helplessness, cognitive distortions, and self-efficacy would predict depression in a sample of eighty patients with multiple scle rosis (MS). Results indicated that depression was significantly related to higher scores on measures of learned helplessness and cognitive distortions, and lower scores on a measure of perceived self-efficacy. Significant correlations were also found between help lessness, cognitive distortions, and self-efficacy. However, depression was not signifi cantly related to disability or disease activity in this sample. When helplessness, cog nitive distortions, and self-efficacy were examined simultaneously in a multiple regression analysis, only helplessness predicted depression after controlling for demo graphic and disease-related variables. Cognitive distortions and self-efficacy did not have an independent effect. Implications of these findings, including issues for future research and treatment, were discussed. Key Words: Multiple sclerosis—Depression—Leamed helplessness—Cognitive distortions—Self-efficacy.
Quadrupole Exciton-Phonon Dynamics at the 151-K Phase Transition in PrAl<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mrow><mml:msub><mml:mrow><mml:mi mathvariant="normal">O</mml:mi></mml:mrow><mml:mrow><mml:mn>3</mml:mn></mml:mrow></mml:msub></mml:mrow></mml:math> (1973)

The dynamics of the 151-K Jahn-Teller phase transition in PrAl${\mathrm{O}}_{3}$ have been studied by means of inelastic neutron scattering; the transition is found to involve a soft $T[101]$ acoustic phonon which in turn is driven soft by a quadrupole exciton mode, an electronic mode involving a wavelike modulation of the ${\mathrm{Pr}}^{3+}$ electric quadrupole moment. We report measurements both of the soft phonon behavior and of the coupled excitations in the crossing region.
An RNA Aptamer Provides a Novel Approach for the Induction of Apoptosis by Targeting the HPV16 E7 Oncoprotein (2013)

This paper includes the first characterisation of the effects of an E7 RNA aptamer in a cell line derived from a cervical carcinoma. Transfection of cells with A2 was correlated with the loss of E7 and the induction of apoptosis. Aptamers specific for a number of cellular and viral proteins have been documented previously; one aptamer (Macugen) is approved for clinical use and several others are in clinical trials. In addition to its role as a molecular tool, A2 could have further applications in the future.
Search for B[subscript s][superscript 0]→μ[superscript +]μ[superscript -] and B[superscript 0]→μ[superscript +]μ[superscript -] Decays with CDF II (2011)

A search has been performed for B[subscript s][superscript 0]→μ[superscript +]μ[superscript -] and B[superscript 0]→μ[superscript +]μ[superscript -] decays using 7 fb[superscript -1] of integrated luminosity collected by the CDF II detector at the Fermilab Tevatron collider. The observed number of B[superscript 0] candidates is consistent with background-only expectations and yields an upper limit on the branching fraction of B(B[superscript 0]→μ[superscript +]μ[superscript -])<6.0×10-[superscript 9] at 95% confidence level. We observe an excess of B[subscript s][superscript 0] candidates. The probability that the background processes alone could produce such an excess or larger is 0.27%. The probability that the combination of background and the expected standard model rate of B[subscript s][superscript 0]→μ[superscript +]μ[superscript -] could produce such an excess or larger is 1.9%. These data are used to determine B(B[subscript s][superscript 0]→μ[superscript +]μ[superscript -])= (1.8[subscript -0.9][superscript+1.1])×10[superscript -8] and provide an upper limit of B(B[subscripts 0]→μ[superscript +] μ[superscript -])<4.0×10[superscript -8] at 95% confidence level.
Synthesis of the Lewis a Trisaccharide Based on an Anomeric Silyl Fluorous Tag. (2005)

The synthesis of the trisaccharide Lewis a was performed using an anomeric fluorous silyl protective group. This methodology allowed us to\nfully characterize each product (NMR, MS) and monitor each synthetic step (TLC). Although the product purifications could be performed by\nfluorous-solid-phase extraction (F-SPE) technology, standard chromatography could be used to effect purification if necessary. Trichloroethoxy\ncarbonyl (Troc) protection of the amino group of the glucosamine moiety was found essential to allow protecting group manipulation of the\nfluorous protected sugar.
BerkMin: A fast and robust SAT-solver (2003)

We describe a SAT-solver, BerkMin, that inherits such features of GRASP, SATO, and Chaff as clause recording, fast BCP, restarts, and conflict clause "aging". At the same time BerkMin introduces a new decision making procedure and a new method of clause database management. We experimentally compare BerkMin with Chaff, the leader among SAT-solvers used in the EDA domain. Experiments show that our solver is more robust than Chaff. BerkMin solved all the instances we used in experiments including very large CNFs from a microprocessor verification benchmark suite. On the other hand, Chaff was not able to complete some instances even with the timeout limit of 16 hours.
<title>Exact numerical technique for the analysis of Bragg reflectors in integrated optical filters</title> (1997)

We present an exact numerical technique for analyzing Bragg reflectors. Bragg reflectors can be used as narrow-band distributed feedback reflectors that reflect at the center of the grating stopband and transmit at frequencies to either side. THese reflectors can be sued as highly selective pass-band filters. These reflectors can be also used as highly selective pass-band filters. Our structure that is realized by the LEAME consists of microcavities inserted in a waveguide suspended in air. These cavities ar air voids placed periodically in a high-refractive index semiconductor material. Recently Zhang et al. realized a broad-band Bragg reflector by placing a 1D array of air holes in a dielectric waveguide without taking into account the power loss in their simulation. Power loss due to radiation at abrupt discontinuities limits the performance of these microcavities.Unlike the other analytical methods no physical approximations are made throughout the entire analysis, so it may be used to analyze any periodic dielectric structure regardless of the geometry or strong discontinuities. Our exact technique uses the local normal modes of the structure to form a transfer matrix for the whole structure. For this reason our method can be used to evaluate exactly the transmitted, reflected and radiated power. We will present later the result of the numerical simulations for a Bragg reflector with few steps.
A novel method for change detection in spectral imagery (2010)

A new method for change detection of two large area scenes based on the point density of the pixel distribution in the hyperspace is presented. This method is derived from the point density approach to hyperspectral analysis, originally developed for material discrimination based on inherent dimension estimation. In this method, two registered large area scenes are tiled for individual scoring and comparison. The point density tail length is estimated for each tile in both scenes. The difference between this value for corresponding tiles indicates whether change has likely occurred in a tile and how significant the change is relative to other changes in the image. The method does not identify changes in individual pixels, but uses a tiling approach to identify changes in small sub-regions of the image. Preliminary results of this methodology are presented for multiple images and changing scene phenomenology.
J0540204 Research on Renewable Energy and Stockpile by Biocoke Technology of Pollution Biomass (2014)

Kinki University launched the Great East Japan Earthquake Reconstruction Support Office in August 2012. Its two main themes are of the reconstruction assistance "From Zero to Plus" and rehabilitation support from the disaster of "To Zero from Minus". However, more than three years after the disaster has passed, we have felt that decontamination has not progressed enough to expect. In this project, we examined the long-term stability effect by the volume reduction of pollution biomass based on Biocoke technology. We suggested that Biocoke is stabilized for a long time from various data. Especially, we was carried to the dissolution test into water from Biocoke including of adhere radioactive Cs-147. Emission of radioactive material from Biocoke reduced until 25%.
Reconfigured Strategy of Network Slices based on Representation Learning in Flex-Grid Optical Networks (2019)

This paper propose a reconfigured strategy of slices in flex-grid optical network based on representation learning. In the proposed method, the resource allocation process will take nodes' correlation into account. Experiments show our strategy has better resource utilization.