gebhart/patrepeval huggingface dataset:
Electrical potentials in bone induced by ultrasound irradiation in the megahertz range (2013)

Low frequency mechanical studies have reported the contribution of stress-induced electrical potentials to bone metabolism. However, the healing mechanism of bone fractures by low intensity ultrasound is not yet clear. We demonstrate that bone can generate electrical potentials by ultrasound irradiation in the MHz range. Electrical potentials were obtained from the output of bovine cortical bone transducers. In the range of 0.7–2.5 MHz, sensitivities of bone transducers were around 1/1000 of a poly (vinylidene fluoride) ultrasonic transducer and did not depend on magnitude and alignment of hydroxyapatite crystallites in bone.
Distribuição geográfica de Aedes Aegypti e Aedes Albopictus em divinópolis/mg utilizando técnicas de geoprocessamento (2013)

O A. aegypti é o principal vetor do DENV. Em 2010, Divinópolis notificou mais de 5 mil casos da doença. Devido a escassez de dados relacionados ao DENV, este trabalho tem como objetivo fazer um monitoramento do Aedes sp. a partir de ovitrampas georreferenciadas. As ovitrampas foram distribuídas por 6 regiões de Divinópolis em 44 pontos. Os ovos coletados foram contados, as larvas eclodidas, identificadas e os dados geoprocessados. Foram coletados 25.633 ovos. Onde fevereiro/2012 obteve o maior número de ovos (5.635). A taxa de ecolsão foi 47%, sendo 72.3% identificadas como A. aegypti e 27.7% como A. albopictus. A. albopictus apresentou maior infestação nas regiões Norte (34,8%). A região Central obteve o maior número de larvas de A. aegypti (24,5%). Neste estudo foi observado a presença dos ovos de Aedes sp. durante todo o ano e uma crescente distribuição da espécie A. albopictus. Sugerindo estudos mais aprofundados sobre o comportamento e adaptação desta espécie.
<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mrow><mml:mi>J</mml:mi><mml:mo>/</mml:mo><mml:mi>ψ</mml:mi></mml:mrow></mml:math>suppression at forward rapidity in Au<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mrow><mml:mo>+</mml:mo></mml:mrow></mml:math>Au collisions at<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mrow><mml:msqrt><mml:msub><mml:mi>s</mml:mi><mml:mrow><mml:mi>N</mml:mi><mml:mi>N</mml:mi></mml:mrow></mml:msub></mml:msqrt><mml:mo>=</mml:mo><mml:mn>200</mml:mn></mml:mrow></mml:math>GeV (2011)

Heavy quarkonia are observed to be suppressed in relativistic heavy-ion collisions relative to their production in $p+p$ collisions scaled by the number of binary collisions. In order to determine if this suppression is related to color screening of these states in the produced medium, one needs to account for other nuclear modifications including those in cold nuclear matter. In this paper, we present new measurements from the PHENIX 2007 data set of $J/\ensuremath{\psi}$ yields at forward rapidity ($1.2<|y|<2.2$) in $\text{Au}+\text{Au}$ collisions at $\sqrt{{s}_{{}_{NN}}}=200$ GeV. The data confirm the earlier finding that the suppression of $J/\ensuremath{\psi}$ at forward rapidity is stronger than at midrapidity, while also extending the measurement to finer bins in collision centrality and higher transverse momentum (${p}_{T}$). We compare the experimental data to the most recent theoretical calculations that incorporate a variety of physics mechanisms including gluon saturation, gluon shadowing, initial-state parton energy loss, cold nuclear matter breakup, color screening, and charm recombination. We find $J/\ensuremath{\psi}$ suppression beyond cold-nuclear-matter effects. However, the current level of disagreement between models and $d+\text{Au}$ data precludes using these models to quantify the hot-nuclear-matter suppression.
Integrated omics in systems biology: The new frontier for environmental biotechnology, ecology, and evolution (2006)

Environmental biotechnology encompasses a wide range of characterization, monitoring and control or remediation technologies that are based on biological processes. Recent breakthroughs in our understanding of biogeochemical processes and genomics are leading to exciting new and cost effective ways to monitor and manipulate the environment. Indeed, our ability to sequence an entire microbial genome in just a few hours is leading to similar breakthroughs in characterizing proteomes, metabolomes, phenotypes, and fluxes for organisms, populations, and communities. Understanding and modeling functional microbial community structure and stress responses in subsurface environments has tremendous implications for our fundamental understanding of biogeochemistry and the potential for natural attenuation or bioremediation of contaminated sites. Monitoring techniques that inventory and monitor terminal electron acceptors and electron donors, enzyme probes that measure functional activity in the environment, functional genomic microarrays, phylogenetic microarrays, metabolomics, proteomics, and quantitative PCR are also being rapidly adapted for studies in environmental biotechnology. Integration of all of these new high throughput techniques using the latest advances in bioinformatics and modeling will enable break-through science in environmental biotechnology. A review of these techniques with examples from field studies and lab simulations will be discussed.
Bounded Computational Capacity Equilibrium (2010)

We study repeated games played by players with bounded computational power, where, in contrast to Abreu and Rubisntein (1988), the memory is costly. We prove a folk theorem: the limit set of equilibrium payoffs in mixed strategies, as the cost of memory goes to 0, includes the set of feasible and individually rational payoffs. This result stands in sharp contrast to Abreu and Rubisntein (1988), who proved that when memory is free, the set of equilibrium payoffs in repeated games played by players with bounded computational power is a strict subset of the set of feasible and individually rational payoffs. Our result emphasizes the role of memory cost and of mixing when players have bounded computational power.
An Improved Synthesis of Estrogens. (1965)

A short step synthesis of estradiol was presented. 1-Vinyl-6-methoxy-1-tetralol (I) was condensed with 2-methyl-1, 3-cyclopentanedione (II)in the presence of Triton B to give dl-3-methoxy-8, 14-secoestra-1, 3, 5(10), 9-tetraene-14, 17-dione (III) which was converted by phosphorus pentoxide into the known dl-3-methoxyestra-1, 3, 5(10), 8, 14-pentaen-17-one(IV). The ketone (IV) was treated with sodium borohydride in methanol, yielding dl-3-methoxyestra-1, 3, 5(10), 8, 14-pentaen-17β-ol(V). Catalytic hydrogenation of this compound over Raney nickel was found to be stereospecific, yielding dl-3-methoxyestra-1, 3, 5, (10), 8-tetraen-17β-ol(VI). This compound was subjected to K-NH3reduction to give dl-estradiol 3-methyl ether (VII).Racemic V was resolved through its 17 l-menthoxyacetate and d-estradiol 3-methyl ether obtained by the above series of reactions was identical with the material of natural origin. dl-Equilenin 3-methyl ether was prepared from dl-3-methoxyestra-1, 3, 5(10), 8-tetraen-17β-ol (VI) by oxidation with Jones' reagent at one step.
Stevens-Johnson Syndrome Induced by Vandetanib (2011)

Vandetanib is a once-daily oral anticancer drug that selectively inhibits key signaling pathways in cancer by targeting vascular endothelial growth factor receptors, epidermal growth factor receptors tyrosine kinase, and rearranged during transfection-dependent tumor cell proliferation and survival. The most frequently reported adverse events attributed to vandetanib include diarrhea, elevated aminotransferase, asymptomatic corrected QT interval prolongation, and hypertension. Though a number of randomized, doubleblind studies, including cutaneous adverse events attributed to vandetanib, have been reported along with these general symptoms, no case of Stevens-Johnson syndrome (SJS) has been reported. This paper demonstrates a case of SJS induced by vandetanib.
Cyclin B1 Expression Regulated by Cytoplasmic Polyadenylation Element Binding Protein in Astrocytes (2011)

Astrocytes are the most abundant cells in the brain, playing vital roles in neuronal survival, growth, and function. Understanding the mechanism(s) regulating astrocyte proliferation will have important implications in brain development, response to injury, and tumorigenesis. Cyclin B1 is well known to be a critical regulator of mitotic entry via its interaction with cyclin-dependent kinase 1. In rat astrocytes, we now show that the mRNA binding protein cytoplasmic polyadenylation element binding protein 1 (CPEB1) is associated with cyclin B1 mRNA and that this interaction is enriched at the centrosome. In addition, if growth-arrested astrocytes are stimulated to divide, CPEB1 is phosphorylated and cyclin B1 mRNA is polyadenylated, both hallmarks of CPEB1 activation, resulting in an increase in cyclin B1 protein. CPEB1 binding to mRNA initially inhibits translation; therefore, removing CPEB1 from mRNA should result in an increase in translation due to derepression. Indeed, when we either knocked down CPEB1 protein with siRNA or sequestered it from endogenous mRNA by expressing RNA containing multiple CPEB1 binding sites, cyclin B1 protein was increased and cell proliferation was stimulated. Our data suggest a mechanism wherein CPEB1 is bound and represses cyclin B1 mRNA translation until a signal to proliferate phosphorylates CPEB1, resulting in an increase in cyclin B1 protein and progression into mitosis. Our results demonstrate for the first time a role for CPEB1 in regulating cell proliferation in the brain.
Prognostic significance of serum alkaline phosphatase measurements in patients with osteosarcoma treated with adjuvant or neoadjuvant chemotherapy (1993)

These data demonstrate that in osteosarcoma of the extremities, pretreatment SAP levels have a prognostic value and they should be considered when comparing the results achieved with different therapeutic protocols and in planning new randomized clinical trials.
Optical Companding (2017)

We introduce a new nonlinear analog optical computing concept that compresses the signal's dynamic range and realizes non-uniform quantization that reshapes and improves the signal-to-noise ratio in the digital domain.
Eichrom`s Diphonix{reg_sign} resin: Production-scale applications in radioactive waste treatment and iron control in copper electrowinning (1997)

Eichrom`s Diphonix{reg_sign} resin has been phased through synthetic scale-up, pilot testing, and production installation in radioactive waste treatment and hydrometallurgical applications. The geminal diphosphonic acid groups of Diphonix resin allow selective retention by cation-exchange and/or chelation. The resin is effective at low pH where sulfonic and carboxylic acid resins are ineffective. Diphonix resin has been used in nuclear facilities to reduce actinide concentrations in radioactive waste effluents and to reduce waste volumes. The high retention of iron(III) by Diphonix resin in acidic sulfate media has led to an installation capable of removing one ton of iron per day from a copper electrowinning stream. This iron control process diminishes cobalt losses in the electrowinning circuit and significantly reduces operating costs. The authors will discuss the development of these Diphonix resin applications.
Effects of the Hybrid Composition of Commercial Lithium-Ion Capacitors on Their Floating Aging (2018)

Lifetime of energy storage systems is a key factor that is extremely influenced by the operating conditions. For this reason, lithium-ion batteries (LiBs) and supercapacitors (SCs) were subjected to accelerated aging tests in several previous research in order analyze their lifespan. Lithium-ion capacitors (LiCs), which fall in between LiBs and SCs, are still considered as a novel technology. Their behavior during accelerated aging tests is not yet well studied in the literature. This paper focuses on studying the degradation of their properties during floating aging. Eighteen samples were tested under three different voltage values and two different temperatures over 12 months. Cells that were discharged to the minimum voltage showed a severe capacitance decrease that was much higher than the one of fully charged cells. The best storage voltage of LiCs was found to be 3 V, which is equivalent to a half charging state. The hybrid structure of LiCs was found to be the major cause of this change in behavior during aging at different voltages. Mechanisms that affect the electrodes and the internal composition of the cells in the diverse conditions were analyzed and predicted.
The Role of Genetics in Defining Reference Values and Health Status (1993)

Since its establishment, the Center for Preventive Medicine in Vandoeuvre-les-Nancy, France, performed specific studies on healthy humans, and its approach was very useful for defining reference values. Prevention should extend its interest to chronic diseases. The majority of important adult disorders are partially genetically determined. Genetic markers are also useful as exclusion or as partition criteria in the production of reference values. Results are presented that were obtained for apolipoproteins E, B and AIV, frequencies of these polymorphisms in the Lorraine population, and relationships between these polymorphisms and lipid metabolism-related parameters. Health checkup centers, in particular those involved in family screening, are well suited for resembling many data concerning environmental factors: tobacco consumption, alimentation habits, or alcohol and drug consumption. Simultaneous determination of genetic markers could allow the determination of an individual's susceptibility or resistance to developing a disease and to prepare a preventive action.
T cell regulation of antibody responses: an I-A-specific, autoreactive T cell collaborates with antigen-specific helper T cells to promote IgG responses. (1985)

In earlier studies we showed that hapten-specific inducer T cell clones specifically induce B cells from immunized donors to secrete IgM antibodies. However, IgG responses were not observed, suggesting that an additional signal(s) was required. In this report, we show that an autoreactive T cell clone produces a factor(s) that collaborates with antigen-specific inducer T cells to promote specific IgG responses. This factor is not restricted by antigen or MHC determinants and promotes IgG production both in vivo and in vitro. These findings suggest that autoreactive cells may play an important role in the regulation of isotype expression.
ChemInform Abstract: PREPARATION AND CHARACTERIZATION OF LITHIUM MAGNESIUM TRIHYDRIDE, LITHIUM DIMAGNESIUM PENTAHYDRIDE, LIMGRH2, LIMGR2H AND LIMG2H3R2 COMPOUNDS (1978)

Abstract Während die Addition von LiAlH 4 (III) zum aus Phenyl‐ Li und Diphenyl‐Mg gewonnenen Mg‐Komplex (IDzum Aluminat (I)neben Mg(II)‐hydrid im Verhältnis l 22 führt, wird bei Zugabe des Magnesats (II) zum Hydrid (III) der Mg‐Komplex (IV) erhalten.
New aspects of cationic polymerization of spiroorthoester: cationic single ring-opening polymerization and equilibrium polymerization (1991)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTNew aspects of cationic polymerization of spiroorthoester: cationic single ring-opening polymerization and equilibrium polymerizationSatoyuki Chikaoka, Toshikazu Takata, and Takeshi EndoCite this: Macromolecules 1991, 24, 25, 6557–6562Publication Date (Print):December 1, 1991Publication History Published online1 May 2002Published inissue 1 December 1991https://pubs.acs.org/doi/10.1021/ma00025a001https://doi.org/10.1021/ma00025a001research-articleACS PublicationsRequest reuse permissionsArticle Views348Altmetric-Citations40LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Effect of photoacid generator concentration on sensitivity, photoacid generation, and deprotection of chemically amplified resists (2002)

The dependence of resist processes (sensitivity, efficiency of photoacid generation, polymer deprotection) on the concentration of the photoacid generator (PAG) in formulations of chemically amplified photoresist was investigated as a function of the concentration of photoacid that was generated upon exposure. Although the sensitivity of a photoresist formulation improved by increasing the concentration of PAG in the resist formulation, the concentration of photoacid required to achieve an appropriate extent of deprotection to render development also increased. Using a standard addition technique, the efficiency of photoacid generation was quantified for resist systems consisting of triphenylsulfonium triflate as the PAG in an environmentally stable chemically amplified photoresist-type polymer primarily composed of 4-hydroxystyrene and tert-butyl acrylate monomers. Determination of the apparent efficiency of photoacid generation (the resist C parameter) allowed the concentration of photoacid within the resist film to be calculated for any exposure dose. Deprotection of the polymer was measured using infrared spectroscopy and analyzed as a function of the photoacid concentration within the resist. We determined from these results that the increase in the concentration of photoacid required for development of the resist was caused by a change in the deprotection process during the postexposure bake and was not due to dissolution inhibition by the unexposed PAG.
Osteoporosis: Guidelines for Management (1996)

Lukert, B; Broy, S; Ciitelli, R\; Fleischmann, R; Gagel, R; Khosla, S; Ledger, G; Lucas, M; Short, B; Maricic, M; Miller, P; Pacifici, R; Sarran, S; Short, M Author Information
Familial Creutzfeldt–Jakob disease with E200K mutation presenting with neurosensorial hypoacusis: Figure 1 (2009)

Creutzfeldt-Jakob disease (CJD) is characterised by rapidly progressive dementia, myoclonus, ataxia, visual disturbances and motor dysfunction. Most of the cases are sporadic. Only 10% to 15% are familial, and the most frequent point mutation is E200K. A 53-year-old man presented with subacute progressive bilateral hypoacusis, with tinnitus in the left ear. During the following months, his hypoacusis worsened and he progressively developed bilateral stocking-type paresthaesia and gait instability. An audiometric examination showed bilateral neurosensorial hypoacusis and nerve conduction studies showed a mixed axonal polyneuropathy. A CT scan and MRI of the brain were normal and the electroencephalography (EEG) showed non-specific changes. He died of respiratory infection 10 months after onset of symptoms. Neuropathological examination showed neuronal loss, punctate, synaptic-like deposits of protease-resistant prionic protein (PrP(RES)) in the cerebral and cerebellar cortices and auditory nuclei. This is a rare case of sporadic CJD presenting with hearing loss.
Evidence fortheInvolvement ofMembranous Bodies in theProcesses Leading toGenetic Transformation inBacillus subtilis (1966)

WOLSTENHOLME, DAVIDR.(Max-Planck-Institut furBiologie, Tubingen, Germany), CORNELIUS A.VERMEULEN, AND GERHARDUSVENEMA.Evidence forthe involvement ofmembranous bodies intheprocessesleading togenetic transformationinBacillus subtilis. J.Bacteriol. 92:1111-1121. 1966.-Data obtained from electron microscopic autoradiographs ofprofiles ofcells ofaBacillus subtilis population exposed toH3-thymidine-labeled donordeoxyribonucleic acid(DNA)during thephaseofmaximal competence indicated thatmolecules originating fromabsorbed DNA areclosely associated withmembranous bodies, particularly with those situated inthecytoplasm, butthat mostifnotall oftheradioactive molecules areoutside thebodies. Itissuggested thatmembranous bodies produce enzymes essential totheeventual incorporation oftransforming DNA intothebacterial genome,ortothebreakdown andutilization orexpulsion ofabsorbed DNA not incorporated astransformant (ortobothprocesses). During thephase ofmaximal competence, thetotal numberofmembranous bodies seeninprofiles increased continuously toasmuchas2.3times thenumbers foundduring earlier stages of culture. Thisincrease was notaccounted forbya decrease inbacterial cellvolume, butresulted froman actual increase intotal volume ofmembranous bodies. The numberofmembranous bodies visibly connecting plasma membrane andnuclear region increased during maximal competence toasmuchas30times thenumbers foundinearlier stages. Asbothincreases werefoundintheabsence ofdonorDNA andonlybeganafter maximal competence was attained, itseemed mostprobable thatthey were an expression ofa physiological state influenced bythecontinuing deficiency ofnutrients inthegrowth mediumduring this phase ofculture.
ChemInform Abstract: FLUORINATED KAURENOIDS. PART 1. SYNTHESIS AND BIOLOGICAL ACTIVITY OF ENT‐15β‐FLUOROKAUR‐16‐ENE, ENT‐17‐FLUOROKAUR‐16‐ENE, AND ENT‐17,17‐DIFLUOROKAUR‐16‐ENE (1980)

Abstract Die Fluorierung der Hydroxykaurene (I) und (IV) mit 2‐Chlor‐N,N‐diethyl‐1 ,1 ,2‐trif1uorethylamin führt in jedem Fall zu dem ent‐1 Sß‐Fluorkauren (II) als Hauptprodukt und zu geringen Mengen des instabilen prim. Fluorids (III).
[Demonstration of a TRH precursor in the pancreas of the newborn rat]. (1986)

This study allows the indirect demonstration of a precursor for TRH in pancreatic extracts of 2-days old rats. The sequential treatment of these extracts with trypsin and carboxypeptidase A is followed by a large increase in Pyroglutamyl Histidine Proline (TRH-OH). The molecular weight of the protein that gives rise to TRH-OH after enzymatic treatment ranges between 30,000 and 40,000 daltons. During ontogenesis. TRH levels decrease earlier and more rapidly than that of TRH-precursor levels. These data suggest that changes in the processing of TRH-precursor play a role in the diminution of TRH concentrations that is observed during the first two weeks of life.