gebhart/patrepeval huggingface dataset:
Testing two Lactobacillus plantarum and Lactobacillus acidophilus strains for their suitability as a lipoid probiotic. (2004)

Two strains of lactobacilli (Lactobacillus acidophilus T-135 and Lactobacillus plantarum 4/97) were selected in order to study their inhibitory properties against frequent udder pathogens (Escherichia coli, Staphylococcus aureus, Streptococcus agalactiae, Streptococcus uberis, Salmonella enteritidis and Bacillus pumilus), their production of organic acids as well as their ability to survive on the teat skin, the teat duct mucosa and in a lipoid emulsion. Both strains inhibited the tested pathogenic microbes and survived on the investigated surfaces and in an emulsion for more than 6 hours and 11 days, respectively.
[Sudden deafness: efficacy of a therapeutic protocol]. (2001)

Sudden hearing loss is an entity of unknown cause. Different theories of its etiology and treatment have been proposed. The objective of our report is to evaluate the efficacy of the therapeutic protocol used in our department in patients with sudden hearing loss. We made a retrospective study of 24 patients who had experienced sudden hearing loss from January 1994 to March 1998. We studied the parameters of age, sex, days of hospitalization, vestibular symptoms, otoscopy, personal history, radiology study, and successive audiograms. The treatment protocol consists of low-dose steroids, pentoxyphylline, and carbogen, and a concentration of 5% CO2 and 95% O2. Treatment was effective, with a recovery rate of 83%. The factors of tinnitus or vertigo, the state of hearing in the opposite ear, and age did not influence the recovery of hearing. However, the form of the audiogram and initial hearing were important prognostic factors.
BIREFRINGENCE COMPENSATION AND TEM00 MODE ENHANCEMENT IN A Nd: YAG LASER (1971)

A Nd: YAG laser has been operated under strong thermal focusing and birefringent conditions and has yielded both linearly polarized output with negligible power loss and TEM00 output of 50–70% of the multimode power. The laser consisted of two Nd: YAG rods separated by a 90° crystal quartz polarization rotator together with a convex mirror and used no special cooling techniques. The performance of this laser, which agreed with theoretical predictions, indicates that this design approach may be generally applicable to the problem of thermally induced aberrations in such systems.
The Rise and Fall of the American Whig Party: Jacksonian Politics and the Onset of the Civil War (1999)

(1999). The Rise and Fall of the American Whig Party: Jacksonian Politics and the Onset of the Civil War. History: Reviews of New Books: Vol. 28, No. 1, pp. 3-4.
Preliminary results of cannulated screw fixation for isolated pubic ramus fractures (2012)

Isolated pubic ramus fractures are common fractures in the elderly, and treatment is typically non-operative. Up to 35 % of patients have a prolonged hospital stay due to pain. A small number of these patients do not respond to standard (non-operative) treatment. We retrospectively reviewed six patients with isolated pubic ramus fractures and persistent pain who were treated with percutaneous retrograde pubic ramus screw fixation. The study group consisted of six women with an average age of 81 years (72-86 years). Patients with symptomatic posterior pelvic ring injuries were excluded. All patients showed improvement after surgery, with three patients pain free and three patients with reduced pain. The mean time spent in the hospital was 9 days (range 3-18 days). There were complications post-operatively: two patients had pneumonia, two with confusional states, and one patient had a urinary tract infection. Despite these events, which are associated with surgery in patients with comorbidites from advanced age, retrograde pubic ramus screw fixation is an effective treatment option for patients with persistent pain from isolated pubic fractures.
Adhesion Between Metals and Epoxy Adhesives Improved (1989)

"Adhesion Between Metals and Epoxy Adhesives Improved." Materials and Processing Report, 4(5), pp. 4–5
Preparation of Some α-(2-Thienyl)-β-arylethylamines<sup>1</sup> (1958)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPreparation of Some α-(2-Thienyl)-β-arylethylamines1A. J. HILL and R. A. BROOKSCite this: J. Org. Chem. 1958, 23, 9, 1289–1292Publication Date (Print):September 1, 1958Publication History Published online1 May 2002Published inissue 1 September 1958https://doi.org/10.1021/jo01103a014RIGHTS & PERMISSIONSArticle Views265Altmetric-Citations8LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (537 KB) Get e-Alertsclose Get e-Alerts
Development and characterization of cationic solid lipid nanoparticles for co-delivery of pemetrexed and miR-21 antisense oligonucleotide to glioblastoma cells (2017)

The practical use of solid lipid nanoparticles (SLNs) in research has been highlighted in the literature, but few reports have combined SLNs with miRNA-based therapy and chemotherapy. We aimed to prepare cationic SLNs (cSLNs) to load anti-miR-21 oligonucleotide and pemetrexed for glioblastoma therapy in vitro. cSLNs were employed to encapsulate both pemetrexed and anti-miR-21 by a high-pressure homogenization method, and then the properties of cSLNs were characterized. We studied cellular uptake and cytotoxicity properties of cSLNs in U87MG cells. cSLNs were 124.9 ± 1.6 nm in size and 27.3 ± 1.6 mV in zeta potential with spherical morphology in the TEM image. cSLNs uptake by U87MG cells was increased significantly higher and more effective than free pemetrexed. These findings suggest that cSLNs represent a potential new approach for carrying both pemetrexed and anti-miR-21 for glioblastoma therapy.
Fish and people: Aquaculture and the social sciences (1992)

Abstract The contributions of sociology, political economy, and anthropology to the development of aquaculture are examined. These disciplines have approached aqua‐culture from two perspectives. There is a body of literature that explores aquaculture's impact on rural communities, treating aquaculture as agriculture and focusing on issues of equity, labor patterns, nutrition, and health. Another approach stresses what aquaculture has in common with fisheries and is concerned with the use of shared resources such as bays and estuaries and an exploration of the possibility of turning fishermen into aquaculturists. Areas in which future work is needed are identified.
Process Outgrowth of Oligodendrocytes Is Promoted by Interaction of Fyn Kinase with the Cytoskeletal Protein Tau (2002)

Fyn kinase plays an important role during myelination and has been shown to promote morphological differentiation of cultured oligodendrocytes. We analyzed the downstream targets of Fyn kinase in oligodendrocytes. Because process outgrowth and wrapping of axons involve cytoskeletal rearrangement, we focused on cytoskeletal proteins linked to Fyn. Here we demonstrate that Fyn binds to the cytoskeletal proteins Tau and alpha-Tubulin in oligodendrocytes. Tau interacts with the Fyn SH3 domain whereas alpha-Tubulin binds to the Fyn SH2 and SH3 domains. To study the function of the Fyn-Tau interaction in oligodendrocytes, we designed a Tau deletion mutant that would compete with endogenous Tau-Fyn binding in transfected cells. The mutant Tau protein binds to the Fyn SH3 domain but lacks the microtubuli interaction domain and thus cannot bind to microtubuli. In the presence of the mutant Tau protein, a reduction of the process number and process length in oligodendroglial cells was observed. This effect is likely to be caused by interference with the Fyn-Tau-microtubuli cascade rather than inactivation of the kinase, because Fyn bound to the mutant Tau retains activity. A similar inhibition of process outgrowth was observed when oliogodendroglial cells were cultured in the presence of Fumonisin B1, an inhibitor of sphingolipid synthesis that prevents the formation of rafts. Because ligation of the cell adhesion molecule F3 on oligodendrocytes leads to activation of Fyn kinase localized in rafts, these findings suggest that recruitment of Tau and Tubulin to activated Fyn kinase in rafts is an important step in the initiation of myelination.
Towards target-level testing and debugging tools for embedded software (1993)

The current process for testing and debugging embedded sojware is ine~ective at revealing errors. There are currently huge costs associated with the validation of embedded applications. Despite the huge costs, the most dl~cult errors to reveal and locate are found extremely late in the testing process, making them even more costly to repm”r. This paper first presents a discussion of embedded testing research andpractice. This discussion raises a need to improve the existing process and tools for embe&@i testing as well as enable better processes and tools for the jWure. To fmilitate this improvement, architectural and software capabilities which support testing and &bugging with minimal intrusion on the executing system must be developed. Execution visibility and control must come @om the underlying system, which should ofJer interjbces to testing and debugging tools in the same numner it offers them to a compiler. Finally we propose txtenswns to the underlying system, which consists of adiiitions to both the architecture and run-time system that will help reulize target-level tools.
Four-transistor interleaved Doherty amplifier (2009)

A Doherty amplifier that combines four transistors is proposed. Two transistors are operated in class-B and are interleaved with another two operated in class-C. The interleaved transistors are driven by a travelling-wave feed and their output currents are combined using a single distributed power combiner.
Synthesis and Characterization of Ifosfamide Intercalated Layered Double Hydroxides (2012)

Two anionic surfactants, sodium dodecyl sulfate (SDS) and sodium dodecylbenzensulfonate (SDBS), were intercalated into Mg2Al layered double hydroxides (LDHs) using the anion exchange method. Then an alkylating oxazaphosphorine anticancer agent, ifosfamide (IFO), was intercalated into the surfactant-modified LDHs. The IFO-surfactant-LDHs nanohybrids were characterized by PXRD, FTIR, TEM, and elemental chemical analyses. The in vitro drug release from the nanohybrids is remarkably lower than that from the corresponding physical mixture at pH 7.5. The obtained results show these IFO-surfactant-LDHs nanohybrids can be used as potential anticancer drug controlled release system.
Information theoretic analysis on transmit power for MIMO wireless channels with imperfect feedback (2005)

The optimal transmission strategy of a single user multiple-input multiple-output(MIMO) wireless communication system which the transmitter has only imperfect feedback of channel state information(CSI) is studied.When this CSI is in terms of channel covariance feedback,the transmit directions for achieving ergodic capacity correspond with the eigenvectors of the channel covariance matrix,while the optimal power distribution can not be solved in closed form.The ergodic capacity function input covariance matrix to characterize the properties of the transmit power distribution for achieving capacity is anlyzed.Theoretical results are illustrated by numerical simulation.
Is maternal mRNA a determinant of tissue-specific proteins in ascidian embryos? (1986)

ABSTRACT The generation of different cell types during embryonic development is thought to be mediated by the combined activity of cytoplasmic factors (determinants), which are localized in the egg, and inductive interactions, which occur between different embryonic cells and tissues. Ascidians, animals that exhibit rapid and exceptionally autonomous development (reviewed by Jeffery, 1985), appear to employ cytoplasmic determinants to generate embryonic cell diversity. Although determinants have not been identified in ascidians or other animals, it is hypothesized that they function in at least two different ways. First, as initially pointed out by Morgan (1934), determinants may be regulatory factors which promote differential gene expression in specific cell lineages. Consistent with this possibility, inhibitors of transcription, added prior to gastrulation, block the appearance of some ascidian tissue-specific enzymes and morphological markers whose expression is regulated by the activity of cytoplasmic determinants (Whittaker, 1973; Crowther & Whittaker, 1984). Second, determinants may be localized factors which promote cell diversification independent of zygotic gene expression. This class of determinants is implicated in specifying crucial embryonic events that occur before the onset of zygotic transcription. Evidence for the second class of determinants in ascidians was first obtained from interspecific hybridization studies. These studies showed that haploid andromerogones, which developed from anucleate eggs of one ascidian species fertilized with sperm of another species, exhibited larval adhesive papillae that were morphologically identical to those of the maternal species (Minganti, 1959).
High‐Performance Plasmonic Sensors Based on Two‐Dimensional Ag Nanowell Crystals (2014)

A high‐performance plasmonic biosensor based on two‐dimensional (2D) Ag nanowell crystals is rationally designed and fabricated by colloidal litho­graphy. The crystals act as 2D metallic gratings that directly couple incident photons to surface plasmon polaritons (SPPs). The nanowell sizes are properly tuned to enable coupling between the SPPs and Raleigh anomalies, which proves to greatly contribute to sharp reflectance dips. Other geometric parameters including the nanowell depth and the lattice constant are respectively adjusted to optimize the lineshape and sensitivity. These inferences and experimental results are verified by finite‐difference time‐domain (FDTD) calculations. In this study, the fabricated crystal with 670 nm lattice constant, 483 nm nanowell size, and 40 nm nanowell depth possesses the highest refractive index sensitivity (RIS) (623.7 nm RIU −1 ), the maximum figure of merit (FOM) (55.2 RIU −1 ), and a very high value of full height/full width at half‐maximum (FH/FWHM) (28.3 ×10 −3 nm −1 ). As a proof‐of‐concept, we adopt the well‐studied antigen‐antibody couple as a model system to illustrate the potential of the nanowell crystal in a quantitative analytical bioassay. The excellent sensing performance, together with the compact structure and the simple read‐out apparatus, suggest that the 2D Ag nanowell crystal is an excellent candidate for a label‐free biosensing platform.
Study of CO2 sorbents for extravehicular activity (1973)

Portable life support equipment was studied for meeting the requirements of extravehicular activities. Previous studies indicate that the most promising method for performing the CO2 removal function removal function were metallic oxides and/or metallic hydroxides. Mgo, Ag2, and Zno metallic oxides and Mg(OH)2 and Zn(OH)2 metallic hydroxides were studied, by measuring sorption and regeneration properties of each material. The hydroxides of Mg and Zn were not regenerable and the zinc oxide compounds showed no stable form. A silver oxide formulation was developed which rapidly absorbs approximately 95% of its 0.19 Kg CO2 Kg oxide and has shown no sorption or structural degeneration through 22 regenerations. It is recommended that the basic formula be further developed and tested in large-scale beds under simulated conditions.
Reacciones Adversas a los Antirretrovirales en pacientes con VIH/SIDA. INSTITUTO PEDRO KOURÍ, 2015 (2017)

Introduccion: Las reacciones adversas a los antirretrovirales se han reportado con el uso de todos estos farmacos y son una de las condiciones por las cuales se cambian los esquemas de tratamiento y se observa menor adherencia. En el Instituto Pedro Kouri las reacciones adversas a los antirretrovirales han sido poco caracterizadas. Objetivos: Caracterizar las reacciones adversas a los farmacos antirretrovirales en pacientes VIH/sida. Metodo : Estudio observacional y transversal de farmacovigilancia activa centrada en el medicamento. Se analizaron 77 pacientes en la Comision Nacional para el tratamiento antirretroviral que presentaron reacciones adversas a los antirretrovirales en el ano 2015. La reaccion adversa se considero la variable principal. Resultados: Las reacciones adversas predominaron en el sexo masculino (77,9%); la edad media de los pacientes fue 39 anos. El medicamento mas reportado fue la zidovudina (27,3%). Las reacciones adversas mas frecuentes fueron anemia (22,0%) y rash (15,6%). Los sistemas de organos de mayor afectacion fueron el hemolinfopoyetico (23,4%) y la piel (19,5%). Las reacciones adversas frecuentes ocuparon (64,9%) seguidas de las raras (18,2%). Se presentaron en mayor frecuencia las reacciones adversas probables (74,0%). Conclusiones: Las caracteristicas de las reacciones adversas a los antirretrovirales se corresponden con lo descrito para estos medicamentos y constituyen un problema para los pacientes VIH/sida, los medicos y los sistemas de salud. El conocimiento de las mismas puede favorecer su adecuado control y manejo en el paciente, con el fin de evitar un cambio anticipado de la Terapia Antirretroviral.
A ROMless LFSR reseeding scheme for scan-based BIST (2003)

In this paper, we present a new LFSR reseeding scheme for scan-based BIST, suitable for circuits with random-pattern-resistant faults. The proposed scheme eliminates the need of a ROM for storing the seeds since the reseedings are performed dynamically by inverting some selected bits of the LFSR register. A time-to-market efficient algorithm is also presented for selecting the reseeding points in the test sequence, as well as a proper seed at each point. This algorithm targets complete fault coverage and minimization of the resulting test length and hardware overhead. Experimental results on ISCAS '85 and ISCAS '89 benchmark circuits demonstrate the advantages of this new LFSR reseeding approach in terms of area overhead and test application time.
Activating Patient Involvement (2007)

Activating Patient Involvement"When patients and their families are educated and understand why and how they need to actively participate in their care, and when they feel empowered to do so, their involvement can help to prevent medical errors and enhance safety." 1 This is the central theme of two important new books, Patients as Partners: How to Involve
Hall Effect in SN and SNS Junctions (1998)

Hall effect in SN and SNS junctions is considered. It is shown that at low temperatures the Hall voltage is significantly suppressed as compared to its normal metal value. The time dependence of the Hall voltage in SNS junctions has a form of narrow pulses with the Josephson frequency.
Physiological Changes in Caged Layers during a Forced Molt (1979)

The effects of forced molting on plasma levels of thyroxine (T4), triiodothyronine (T3), and adrenal cholesterol and total adrenal steroid content were studied. Commercially available strains of Single Comb White Leghorn (SCWL) hens, reared and maintained under commercial conditions, were used in the three trials. The hens were moved to environmentally modified facilities prior to the forced molt which was accomplished by reducing daylength and by withdrawing feed and water. Egg production ceased within one week of initiation of this procedure. The hens were sampled either daily or an alternate days for up to 22 days beginning at the time of feed removal. Plasma T4 initially decreased upon removal of feed, but increased above control levels by the sixth day of feed withdrawal. Plasma T3 levels remained relatively constant throughout the feed withdrawal period. Resumption of feeding with a fortified ground corn ration resulted in a decrease in T4 and concomitant increase in T3. Changes in adrenal cholesterol and total adrenal steroids were not consistent. However, there was a trend toward increased total adrenal steroids during feed withdrawal, and an increase in adrenal cholesterol upon the resumption of feeding.
Mental Simulation of Action in the Service of Action Perception (2007)

We used the quantitative 14C-deoxyglucose method to map the activity pattern throughout the frontal cortex of rhesus monkeys, which either grasped a three-dimensional object or observed the same grasping movements executed by a human. We found that virtually the same frontal cortical networks were recruited for the generation and the perception of action, including the primary motor cortex (MI/F1), premotor cortical areas (F2, F5, and F6), the primary (SI) and supplementary (SSA) somatosensory cortex, medial cortical areas (8m and 9m), and the anterior cingulate. The overlapping networks for action execution and action observation support the notion that mental simulation of action could underlie the perception of others' actions. We suggest that the premotor and the somatotopic MI/F1 activations induced by action observation reflect motor grasp of the observed action, whereas the somatotopic SI and the SSA activations reflect recruitment of learned sensory-motor associations enabling perceptual understanding of the anticipated somatosensory feedback. We also found that the premotor activations were stronger for action observation, in contrast to the primary somatosensory-motor ones, which were stronger for action execution, and that activations induced by observation were bilateral, whereas those induced by execution were contralateral to the moving forelimb. We suggest that these differences in intensity and lateralization of activations between the executive and the perceptual networks help attribute the action to the correct agent, i.e., to the "self" during action execution and to the "other" during action observation. Accordingly, the "sense of agency" could be articulated within the core components of the circuitry supporting action execution/observation.
MELANISM IN WHEAT INDUCED BY HIGH TEMPERATURE AND HUMIDITY (1944)

Results of experiments performed in the greenhouse have shown that, under conditions of a high temperature especially when combined with a high humidity, melanistic areas may develop on the glumes, lemmas, peduncles, and internodes of Apex and Renown wheat in the absence of any infection by pathogenic organisms.
A clinical study of the treatment prescribed Mahwangbalpyotang for the Taeumin's Baechupyobyung symptom accompanying chill and fever (2000)

URI(Upper respiratory infection) is caused by virus, lose of balance from change of weather and ahylaxis, etc. So it dose not affect seriously, but in some cases it can cause complication disease depend on the healthfulness of an individual. The case is about a patient who is 21 years old lady, suffered by chill, fever, coughing after experiencing unhealthiness by an excess fatigue. The patient was treated by Mahwangbalpyotang and showed an improvement. This paper describe the process and contents about the way patient was cured.
A bipolar electrode for vascular electrocoagulation with alternating current. (1980)

A bipolar electrode for transcatheter electrocoagulation with alternating current is described. This electrode avoids the problem of variation of the electric impedance of the monopolar electrode/ground plate system. It allows quick, safe, and reliable endovascular occlusion of vessels.