gebhart/patrepeval huggingface dataset:
Department of Animal Sciences research and reviews: swine 2001 (2001)

Ascorbic acid synthesis in fetal, nursing, and weanling pigs / S. Ching and D. C. Mahan -- Effect of dietary energy source (carbohydrate or soybean oil) on postweaning pig / S. Ching and D. C. Mahan -- Effects of dietary lysine level and source, and added dextrose on lactating sow and litter performance / J. C. Peters and D. C. Mahan -- Efficacy of a plant/yeast protein source in weaning pig starter diets / T. G. Wiseman, D. C. Mahan, B. G. Harmon, and N. L. Trottier -- Evaluating the effects of soybean meal particle size on amino acid heal digestibility in grower-finisher swine / N. D. Fastinger and D. C. Mahan -- Particle-size evaluation of grain fed on Ohio swine operations / D. E. Ricker and S. J. Moeller -- An investigation into the genetic controls of pork quality: I. Association studies with leptin receptor, melanocortin-4 receptor, melanocortin-5 receptor, and peroxisome proliferator activated receptor-g. / R. Emnett, S. Moeller, K. Irvin, M. Rothschild, G. Plastow, and Rodney Goodwin -- An investigation into the genetic controls of pork quality: II. Association studies with heart fatty acid binding protein-1 and calpastatin / R. Emnett, S. Moeller, K. Irvin, M. Rothschild, G. Plastow, and Rodney Goodwin -- Physical assignment of adipocyte determination and differentiation factor-1 and pyruvate dehydrogenase E1-alpha in the pig / R. Emnett, S. Moeller, K. Irvin, M. Rothschild, and Eli Grindflek -- Examination of the relationship between the prolactin receptor gene and reproductive tract components in swine / B. J. Isler, K. M. Irvin, M. E Rothschild, and G. J. Evans -- The association between the estrogen receptor locus and growth, carcass, and developmental traits in pigs / T. D. Leeds, K. M. Irvin, and S. J. Moeller -- Utilizing muscle glycolytic potential to indicate Rendement Napole gene status in Hampshire-sired pigs / S. J. Moeller, R. S. Emnett, T. J. Baas and K. M. Irvin
Corrigenda (1970)

M. H. Fisch, H. D. Pierce, A. L. Thakkar, L. G. Tensmeyer, R. B. Hermann, W. L. Wilham, P. Rigo, M. Bressian, B. Corain and A. Turco, J. Chem. Soc. D, 1970, 1128 DOI: 10.1039/C29700001128
Overexpression of Human Hepatic Lipase and ApoE in Transgenic Rabbits Attenuates Response to Dietary Cholesterol and Alters Lipoprotein Subclass Distributions (1999)

The effect of the expression of human hepatic lipase (HL) or human apoE on plasma lipoproteins in transgenic rabbits in response to dietary cholesterol was compared with the response of nontransgenic control rabbits. Supplementation of a chow diet with 0.3% cholesterol and 3.0% soybean oil for 10 weeks resulted in markedly increased levels of plasma cholesterol and VLDL and IDL in control rabbits as expected. Expression of either HL or apoE reduced plasma cholesterol response by 75% and 60%, respectively. The HL transgenic rabbits had substantial reductions in medium and small VLDL and IDL fractions but not in larger VLDL. LDL levels were also reduced, with a shift from larger, more buoyant to smaller, denser particles. In contrast, apoE transgenic rabbits had a marked reduction in the levels of large VLDLs, with a selective accumulation of IDLs and large buoyant LDLs. Combined expression of apoE and HL led to dramatic reductions of total cholesterol (85% versus controls) and of total VLDL+IDL+LDL (87% versus controls). HDL subclasses were remodeled by the expression of either transgene and accompanied by a decrease in HDL cholesterol compared with controls. HL expression reduced all subclasses except for HDL2b and HDL2a, and expression of apoE reduced large HDL1 and HDL2b. Extreme HDL reductions (92% versus controls) were observed in the combined HL+apoE transgenic rabbits. These results demonstrate that human HL and apoE have complementary and synergistic functions in plasma cholesterol and lipoprotein metabolism.
Competencia de análisis didáctico en la formación inicial de profesores de matemática de Chile (2015)

En esta investigacion se presenta un diagnostico del nivel de desarrollo de la  competencia reflexiva de un grupo de futuros profesores chilenos que estudian de la carrera de pedagogia general basica en la Universidad Catolica del Maule. Se trata de un estudio cualitativo que sigue un diseno de caso unico, compuesto por un grupo de alumnos y alumnas de la carrera de Educacion General Basica con Mencion en Matematica. Los resultados obtenidos muestran un bajo nivel de esta competencia.
Effect of (des-Tyr1)-γ-endorphin on Prolactin Secretion (1981)

<h3>To the Editor.—</h3> Verhoeven and colleagues (Archives1979;36:294-298) have reported that (des-Tyr<sup>1</sup>)-γ-endorphin (DTγE; β-lipotropin<sub>62-77</sub>) has antipsychotic properties in some schizophrenic patients, but this was not replicated in two recent studies.<sup>1.2</sup>Animal experiments have suggested that DTγE may have direct or indirect neuroleptic properties. Neuroleptics are potent stimulants of prolactin secretion in the rat; most neuroleptics, with the exception of clozapine and melperone, are also potent stimulants of prolactin secretion at therapeutic dosages in man.<sup>3</sup>(Des-Tyr<sup>1</sup>)-γ-endorphin has been identified in the pituitary of man and the rat.<sup>4</sup>We were interested in determining the effect of DTγE on prolactin secretion in man and laboratory rats. <h3>Subjects and Methods.—</h3> We have now treated four male schizophrenic patients (diagnosis by Research Diagnostic Criteria) with intramuscular injections of DTγE in dosages of 1 to 10 mg/day. All were admitted because of a recent exacerbation of their psychoses. Dosages greater
ChemInform Abstract: Oxidative Esterification of Primary Alcohols by NaBrO3/NaHSO3 Reagent in Aqueous Medium. (1996)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
On the Use of U-Net for Dominant Melody Estimation in Polyphonic Music (2019)

Estimation of dominant melody in polyphonic music remains a difficult task, even though promising breakthroughs have been done recently with the introduction of the Harmonic CQT and the use of fully convolutional networks. In this paper, we build upon this idea and describe how U-Net- a neural network originally designed for medical image segmentation - can be used to estimate the dominant melody in polyphonic audio. We propose in particular the use of an original layer-by-layer sequential training method, and show that this method used along with careful training data conditioning improve the results compared to plain convolutional networks.
Formation of Fatty Acid-degrading, anaerobic granules by defined species (1996)

An endospore-forming, butyrate-degrading bacterium (strain BH) was grown on butyrate in monoxenic coculture with a methanogen. The culture formed dense aggregates when Methanobacterium formicicum was the methanogenic partner, but the culture was turbid when Methanospirillum hungatei was the partner. In contrast, a propionate-degrading, lemon-shaped bacterium (strain PT) did not form aggregates with Methanobacterium formicicum unless an acetate-degrading Methanosaeta sp. was also included in the culture. Fatty acid-degrading methanogenic granules were formed in a laboratory-scale upflow reactor at 35(deg)C fed with a medium containing a mixture of acetate, propionate, and butyrate by using defined cultures of Methanobacterium formicicum T1N, Methanosaeta sp. strain M7, Methanosarcina mazei T18, propionate-degrading strain PT, and butyrate-degrading strain BH. The maximum substrate conversion rates of these granules for acetate, propionate, and butyrate were 43, 9, and 17 mmol/g (dry weight)/day, respectively. The average size of the granules was about 1 mm. Electron microscopic observation of the granules revealed that the cells of Methanobacterium formicicum, Methanosaeta sp., butyrate-degrading, and propionate-degrading bacteria were dispersed in the granules. Methanosarcina mazei existed inside the granules as aggregates of its own cells, which were associated with the bulk of the granules. The interaction of different species in aggregate formation and granule formation is discussed in relation to polymer formation of the cell surface.
1 Gb/s Si high quantum efficiency monolithically integrable λ=0.88 μm detector (1995)

We propose and demonstrate a 1 Gb/s high quantum efficiency Si MSM metal-semiconductor-metal detector which is complementary metal-oxide semiconductor compatible. The detector absorbs over 50% of the light entering the active layer at a wavelength of λ=0.88 μm.
Profiles of the pharmacologic response of positive and negative symptoms in schizophrenia (1987)

Summary The delineation of the symptoms of schizophrenia into positive and negative types has been an important trend in psychiatric research over the past decade. This approach reflects renewed interests in clinical description and in developing etiologic hypotheses. The responsivity of positive and negative symptoms to neuroleptic and other pharmacotherapies, an issue of considerable clinical and research importance, however, remain in controversy. We have observed that double-blind fluphenazine administration to 19 schizophrenic inpatients who had been maintained free from neuroleptic treatment for an extended period of time resulted in significant decreases in both positive as well as negative symptoms. The time course of symptom change differed, however, and the change in symptoms was not correlated, suggesting that the underlying pathophysiologies of positive and negative symptoms are only partially overlapping. The relative balance between positive and negative symptoms in individual patients, a putative schizophrenia trait characteristic, was found to be significantly altered by neuroleptic treatment, raising questions about the reliability of this classification approach. In longitudinal studies in which plasma levels of the dopamine metabolite, homovanillic acid (HVA), were measured, change in negative symptoms associated with neuroleptic withdrawal and treatment were correlated, respectively, with changes in levels of plasma HVA. These data further support a relationship between negative symptoms and dopaminergic function. In addition to neuroleptic-induced reductions in negative symptoms, the augmentation of neuroleptic antipsychotic effects by the triazolobenzodiazepine, alprazolam, includes improvement in negative and positive symptoms in responsive patients. These data including longitudinal studies of individual patients suggest that negative as well as positive symptoms respond to pharmacologic intervention. The clinical and research implications of these findings are discussed.
Mycoplasma-Dependent Activation ofNormalLymphocytes: RoleofArginine andNonviable Mycoplasma Antigen inthe Induction ofLymphocyte-Mediated Cytotoxicity forSyngeneic MouseTarget Cells (1977)

cytotoxicity induction bynormal CBA mouse lymphocytes was investigated. Also, nonviable antigens ofM.arthritidis were assayed for their ability toinduce a cytotoxic response.Thepresenceofadditional arginine intheculture mediumhadno significant effect on theamountofcytotoxicity produced. Insome cases,an increase incytotoxicity was seeninthepresenceof additional arginine. Aminoacidanalysis oftheculture supernatants showedthat thearginine inthenonsupplemented mediumwas exhausted during theassay, whereas ampleamountsofarginine were present inthesupplemented medium. However, inbothcases,theamountofcytotoxicity was comparable. Nonviable antigens ofM.arthritidis were unable toinduce a significant cytotoxic response inthepresenceofnormal lymphocytes. Thesame antigens exhibited asuppressive responsewhentested forblastogenesis inthepresenceofnormallymphocytes. A discussion oflymphocyte involvement ispresented. Inthepreceding report (1), wedescribed a mycoplasma-mediated lymphocytotoxicity reaction against allogeneic andsyngeneic fibroblast target cells thatwasdependent uponthe presence ofviable Mycoplasma arthritidis or M.hominis. Thedegree ofcytotoxicity, asmeasured bytherelease of5Cr, increased inalinear mannerduring the48-hassay andwasdependentuponthenumberoforganisms inoculated. Thecytotoxic reaction wasnotduetoatoxic effect ofthemycoplasmas onthetarget cells alone, since intheabsence oflymphocytes no response wasseen.Atleast 6hwererequired forthelymphocytes tobecomeactivated. Previous reports haveshownthateither viable arginine-utilizi ng mycoplasmas orextracts preparedfromtheseorganisms areinhibitory to antibody synthesis, blastogenesis, andmixed lymphocyte culture reactions (4,10,15). These effects areduetothearginine deiminase complex, sincetheycanbeovercomebyadding excess arginine, heating themycoplasma extracts, orremoving theinhibitory factor by washing thecells. Asreviewed byStanbridge (21), mycoplasma-mediated
Skin color reactions - Separation of contributing chromophores (2002)

We have strong evidence that mixed vascular and pigment reactions cannot be visually separated and that blood stasis can be confused with pigmentation. The involvement of each chromophore can only be identified spectroscopically.
Effect of Instructions on Isokinetic Trunk Strength Testing Variability, Reliability, Absolute Value, and Predictive Validity (1992)

Although isokinetic strength testing has been in use for more than two decades, and numerous studies have addressed isokinetic performance of the lumbar spine, the effect of instructions on isokinetic trunk strength has not been studied. In a sample of 30 healthy women, this study examined the effect of "high-demand" instructions on lumbar strength performance. High-demand instructions were found to have a substantial positive effect on performance variability, reliability, absolute magnitude, and validity. Under these conditions, isokinetic trunk strength was found to be predictive of performance in a frequent lifting-lowering task.
Rhodosamin, Isolierung, Konstitution und Konfiguration (1963)

Abstract Aus Hydrolysaten von Rhodomycingemischen wurde die Tridesoxy‐dimethyl‐amino‐hexose Rhodosamin C 8 H 17 NO 3 als kristallisiertes Hydrochlorid isoliert. Wäßr. Bariumhydroxid verwandelt Rhodosamin in 2‐Desoxy‐l‐fucose und L‐Boivinose. Dieser Befund zusammen mit dem NMR‐Spektrum der beiden anomeren Rhodosamin‐diacetate zeigt, daß Rhodosamin die 2.3.6‐Tridesoxy‐3‐dimethylamino‐L‐lyxo‐hexose ist.
<scp>CD</scp>30 expression by bone marrow mast cells from different diagnostic variants of systemic mastocytosis (2013)

The increased expression of CD30 associated with absence of CD25 contributes to the diagnosis of WDSM and its distinction from other subtypes of SM. By contrast, CD30 expression did not contribute either to prognostic stratification of ISM or to the differential diagnosis between ISM and aggressive SM cases.
Synthesis, NMR-solution structure and biological activity of β-peptides (2000)

In this thesis, the synthesis of oligomers of -amino acids (-peptides) is described.Their secondary structure is investigated by several techniques, in particular nuclear magnetic resonance (NMR) spcctroscopy, but also circular dichroisrn and infrared spectroscopy.Moreover, their interactions with biological systems such as receptors or cells are studied.In a first part, NMR-spectroscopy is used to study the secondary structure of -peptides.In generat a11 resonances are assigned in the IH_ (and sometimes 13C_) NMR speerrum by a combination of COSY, TOCSY/ HSQC and HMBC techniques.The structural information is accessible from the nuclear overhauser effect (NOE) or from coupling constants.These experimental values are then used in simulated annealing calculations to genera te models of the conformation present, i. e. the solution structure.It was possible to determine a 3 14 helix for several -peptides such as 2-peptides A/ 2,3_peptides Band 3-peptides C.Moreover, it was shown that replacement of amide groups by thioamides does A B c alter this secondary structure.Attempts to detect this conformational type in aqueous solution for compounds such as C by NMR-spectroscopy failed.It was shown in a next project by CD-and NMR-spectroscopy that 3peptides such as C display linear meliing curoes up to 393 K (120C) in methanol solution and do not show a melting point.It is thus concluded that the 3 14 helix is populated in the temperature range investigated.Moreover, it may be deduced from the experimental evidence that the mechanism of -peptide folding is non-cooperative.Surprisingly, when shifting the side-chain of every second amino acid in C from the -to the o.-carbon resulting in D, a new and completely different structure -the 12/10/12-helix -is found in methanol solution.It is characterized
Effects of Corynebacterium parvum treatment and Toxoplasma gondii infection on macrophage-mediated cytostasis of tumour target cells. (1976)

Injection of mice with Corynebacterium parvum or living or killed Toxoplasma gondii was studied to determine the efficacy of these treatments in activating peritoneal macrophages to inhibit the uptake of [3H]TdR (cytostasis) by tumour target cells in vitro. In the presence of activated macrophages from mice treated i.p. with a wide dose range of either C. parvum or living Toxoplasma, cytostasis was usually greater than 99%. This population of activated macrophages was transient in C. parvum-treated mice, but persists, probably for life, in Toxoplasma-infected mice. Whereas the i.p. route of administration of C. parvum was more efficient in activating macrophages than the i.v. route, the s.c. route appeared to be relatively ineffective. Treatment with killed Toxoplasma by any route was also relatively ineffective in activating macrophages. In contrast Toxoplasma infection resulted in highly activated peritoneal macrophages, regardless of the route of administration. Depending upon the route of initial treatment, the route of readministration of C. parvum had either no appreciable effect or resulted in a marked alteration in the cytostatic capacity of peritoneal macrophages.
Dose-Response Relationship of Diethylnitrosamine-Initiated Tumors in Neonatal Balb/c Mice: Effect of Phenobarbital Promotion (1988)

The dose-response of diethylnitrosamine (DENA) initiation of hepatocarcinogenesis was determined in infant Balb/c male mice with and without subsequent phenobarbital treatment. Male Balb/c mice received a single intraperitoneal injection of DENA (0, 2.5, 10.0, 25.0 or 50.0 micrograms/gbw) in saline on day 15 of age. Ninety mice were treated at each dose level. At weaning, mice received either deionized drinking water (45 mice per group) or deionized drinking water containing 500 mg/L sodium phenobarbital (PB) (45 mice per group). Mice from each group were sacrificed 12, 24, and 40 weeks post-weaning. Liver and lung tumors were found in DENA-only-treated and DENA + PB-treated mice. In DENA-only-treated mice, the incidence and number of hepatic adenomas were similar (not dose-dependent) at DENA doses of 10, 25, and 50 micrograms/gbw at each of the 3 sampling times. DENA-only-treated mice did display a time-related increase in hepatic adenoma incidence and number at each dose. In PB-treated mice, the hepatic adenoma number was dependent upon the dose of DENA between 2.5 and 50 micrograms/gbw. PB treatment following DENA administration resulted in a decrease in the time required for the detection of hepatic adenomas and increased the number of hepatic adenomas at most sampling times compared to the mice that received DENA only. Hepatocellular carcinomas (HPC) were detected in mice receiving the highest DENA doses (25 and 50 micrograms/gbw). PB treatment increased the number and incidence of HPC and decreased the time of first detection of HPC.(ABSTRACT TRUNCATED AT 250 WORDS)
Cortical bone loss and measurements of the second metacarpal bone. I. Comparisons between adult Guamanian Chamorros and American caucasians (1982)

The amount of radiographically detectable cortical bone, as determined by measurements of the second metacarpal, was evaluated in 42 male and 45 female Guamanian Chamorros and compared with the degree of bony demineralization in U.S. Caucasians participating in the Baltimore Longitudinal Study on Aging of the Gerontology Research Center. All Chamorros were individually matched to the Caucasian participants for age, sex, and menopause status. Chamorros of both sexes showed bilateral asymmetry in bone measurements and in the amount of cortical bone. Both Chamorro and Caucasian males had longer second metacarpals and more cortical bone than females. Caucasian males, however, had longer and larger second metacarpals than Chamorro males. Despite differences in the length and total width, Chamorro and Caucasian participants generally showed no significant differences in the amount of cortical bone or percent cortical area in the second metacarpal, suggesting that larger bones may not always indicate greater cortical mass. Although cross-sectional data suggested apparent age differences in the onset and rate of bone loss between Chamorros and Caucasians, the numbers of participants were too small to allow meaningful age-by-age statistical comparisons.
SURFACE MODIFICATION OF METALLIC IMPLANTS TO ENHANCE OSTEOGENESIS (2009)

Surface topology and chemistry play a role in effecting osseointegration of dental and orthopedic implants with surrounding bone. Titanium dioxide (TiO 2 ) nanofilms, functionalized with BMP‐2, was investigated as an approach to fabricate an instructional surface coating. Six, nine and twelve‐layered TiO 2 substrates were also studied to investigate the additive effect of surface roughness. Osteoblast growth, functionality and matrix mineralization on nanofilms were evaluated. Cell proliferation decreased with increasing surface roughness on both uncoated and BMP‐2 coated TiO 2 substrates as indicated by MTT results. A significant reduction in cell proliferation was also observed on BMP‐2 coated substrates in comparison with uncoated substrates. Osteonectin and osteopontin expression on BMP‐2 coated substrates was significantly greater than that on uncoated substrates suggesting an enhanced osteogenic effect by BMP‐2 on osteoblast protein expression. Varying layers of TiO 2 did not measurably affect osteonectin and osteopontin expression by osteoblasts seeded on both uncoated and BMP‐2 coated substrates. A significant enhancement in calcium production was observed with increasing layers of TiO 2 on both sets of experimental substrates. Increase in calcium levels and deposition on BMP‐2 immobilized substrates showed an enhanced osteogenic effect resulting in increased osteoblast mineralization. This study demonstrated that BMP‐2 could be immobilized onto TiO 2 substrates via nanoassembly and that osteoblast osteogenic activity can be directly influenced by a bioactive substrate. This study suggests that functionalized TiO 2 nanofilms may lead to the development of implants with better osseointegration and enhanced durability.