gebhart/patrepeval huggingface dataset:
In Situ Monitoring of Cellulase Activity by Microgravimetry with a Quartz Crystal Microbalance (2009)

Quartz crystal microgravimetry (QCM) was used to investigate the interactions between cellulase enzymes and model cellulose substrates. The substrates consisted of thin films of cellulose that were spin-coated onto polyvinylamine (PVAm) precoated quartz crystal sensors carrying conductive gold surfaces. In QCM the quartz crystals are piezoelectrically driven and the frequency and dissipation shifts allow monitoring of substrate hydrolysis at various temperatures and enzyme concentrations in situ and in real time. The changes in frequency of cellulose-coated quartz resonators during their incubation in cellulase solutions were related to contributions from the liquid phase properties, the adsorptions of cellulase enzymes, and the hydrolysis of the substrate. Cellulase adsorption was found to be nonspecific and irreversible on gold-, PVAm-, and cellulose-coated quartz crystal sensors. The contribution to frequency shifts due to the bulk fluid properties of the cellulase solutions (at concentrations lower than 0.5 mg/mL) was minimal compared to the frequency shifts produced by cellulase binding. The maximum frequency decreases were fitted to a Langmuir model. The adsorption constant and the maximum adsorption were estimated by the fitting parameters of this model. The hydrolysis process was modeled by using a dose-response model that was then used to estimate the maximum hydrolysis rate, to compare the relative effects of temperature on adsorption and hydrolysis rate, and to obtain the apparent activation energy of cellulose hydrolysis. The hydrolysis rate increased with incubation temperature while apparent adsorption decreased. The apparent activation energy for the hydrolysis of the cellulose films employed was calculated to be 37 kJ/mol.
Empirical lower bounds on the complexity of translational equivalence (2006)

This paper describes a study of the patterns of translational equivalence exhibited by a variety of bitexts. The study found that the complexity of these patterns in every bitext was higher than suggested in the literature. These findings shed new light on why "syntactic" constraints have not helped to improve statistical translation models, including finite-state phrase-based models, tree-to-string models, and tree-to-tree models. The paper also presents evidence that inversion transduction grammars cannot generate some translational equivalence relations, even in relatively simple real bitexts in syntactically similar languages with rigid word order. Instructions for replicating our experiments are at http://nip.cs.nyu.edu/GenPar/ACL06
Peripheral oculomotor palsy affects orienting of visuospatial attention (2001)

Patients affected by VI cranial nerve palsy were required to orient their attention in monocular vision and to detect a stimulus appearing either in attended or in unattended locations. Results showed that while during non-paretic eye vision stimulus detection in the attended location was faster than that in the unattended one, during paretic eye vision no difference in detection speed was present. However, in this latter condition, detection speed in both attended and un attended locations were as fast as that measured during non-paretic eye vision in attended location. Demonstration that peripheral oculomotor impairment influences monocular covert orienting of visuospatial attention strongly support the idea that visuospatial attention and oculomotor mechanisms share similar cortical networks.
New insights on Ni-based catalysts for stereospecific polymerization of butadiene (2012)

A new class of nickel catalysts for stereospecific polymerization of butadiene Ni(COD)2/[X][B(C6F5)4] (X = CPh3 or HNMe2Ph) was investigated and compared to the conventional ternary system Ni(O2CC7H15)2/BF3·OEt2/AlEt3. Both families of catalysts showed high activity and stereospecificity but catalysts based on the relatively non-coordinating anion B(C6F5)4− displayed lower molar masses. The combinations of Ni(O2CR)2 with AlEt3/[CPh3][B(C6F5)4] and of Ni(COD)2 with BF3·OEt2, [CPh3][B(C6F5)4]/BF3·OEt2 and AlEt3/BF3·OEt2 were also implemented. The polymerization tests using the resulting catalysts demonstrated that in the case of the industrial catalyst Ni(O2CR)2/BF3·OEt2/AlEt3, the formation of the active species is based on the reduction of Ni(O2CR)2 in the presence of AlEt3 followed by the re-oxidation of nickel(0) to nickel(II) by butadiene leading to the bis(allyl) complex Ni(C12H18). A cationic active species is finally obtained by the activation of Ni(C12H18) with a fluorinated compound formed by the reaction of BF3·OEt2 with AlEt3.
A model for the functional segregation of ß-granules in the B-cell (1974)

info:eu-repo/semantics/published
Predictors of discontinuing overactive bladder medications (2009)

Persistence with OAB medications might be improved by addressing predictors of discontinuation in the management of OAB, by proactively informing patients about the severity of antimuscarinic adverse effects, and dosing regimens. Bother associated with the key OAB symptom, urgency, is a predictor of discontinuation of treatment.
Calibration and validation of a spar-type floating offshore wind turbine model using the FAST dynamic simulation tool (2014)

In this study, high-quality computer simulations are required when designing floating wind turbines because of the complex dynamic responses that are inherent with a high number of degrees of freedom and variable metocean conditions. In 2007, the FAST wind turbine simulation tool, developed and maintained by the U.S. Department of Energy's (DOE's) National Renewable Energy Laboratory (NREL), was expanded to include capabilities that are suitable for modeling floating offshore wind turbines. In an effort to validate FAST and other offshore wind energy modeling tools, DOE funded the DeepCwind project that tested three prototype floating wind turbines at 1/50<sup>th</sup> scale in a wave basin, including a semisubmersible, a tension-leg platform, and a spar buoy. This paper describes the use of the results of the spar wave basin tests to calibrate and validate the FAST offshore floating simulation tool, and presents some initial results of simulated dynamic responses of the spar to several combinations of wind and sea states. Wave basin tests with the spar attached to a scale model of the NREL 5-megawatt reference wind turbine were performed at the Maritime Research Institute Netherlands under the DeepCwind project. This project included free-decay tests, tests with steady or turbulent wind and still water (both periodic and irregular waves with no wind), and combined wind/wave tests. The resulting data from the 1/50th model was scaled using Froude scaling to full size and used to calibrate and validate a full-size simulated model in FAST. Results of the model calibration and validation include successes, subtleties, and limitations of both wave basin testing and FAST modeling capabilities.
Ion distribution profiles between polar and charged membranes as observed by anomalous X-ray diffraction (1996)

The distribution profiles of rubidium ions near polar, zwitterionic 1,2-di stearoyl-sn-glycero-3-phospho choline (DSPC) and charged, anionic 1,2-di stearoyl-sn-glycero-3-phospho glycerol (DSPG−) membranes were determined by means of anomalous X-ray diffraction close to the K-absorption edge of Rb+, which was measured to be 15.225 keV. The samples were kept in the Lβ'-phase at 30 °C. The DSPC suspensions in 2 M RbCl were examined at 15.125 keV, 15.196 keV, 15.210 keV, the DSPG− suspensions in 0 M RbCl and 2 M RbCl at 14.667 keV and 15.196 keV. This gave up to seven peaks in the powder-like diffraction pattern and revealed, for the first time directly, different rubidium ion distributions in either of the investigated systems: rubodium ions are enriched by 100% in the proximity of the charged DSPG− headgroups and depleted by 25% from the vicinity of the zwitterionic DSPC headgroups. The latter phenomenon results in rubidium ion concentration maximum in the aqueous compartment between polar, but uncharged bilayers.
A Resolution Calculus for Shortening Proofs (2005)

Journal Article A Resolution Calculus for Shortening Proofs Get access Nicolas Peltier Nicolas Peltier Leibniz-IMAG, CNRS, 46 avenue Felix Viallet, 38031 Grenoble Cedex, France. E-mail: Nicolas.Peltier@imag.fr Search for other works by this author on: Oxford Academic Google Scholar Logic Journal of the IGPL, Volume 13, Issue 3, May 2005, Pages 307–333, https://doi.org/10.1093/jigpal/jzi027 Published: 01 May 2005
Diagnostic Threshold for Conduct Disorder in Girls and Boys (2003)

Concerns about gender bias in the diagnostic criteria for conduct disorder (CD) have prompted some researchers to recommend that the diagnostic threshold in girls be lowered. Since CD is a highly familial condition, the authors assessed the diagnostic validity of subthreshold CD in girls using family study methodology. They compared the rates of antisocial disorders (CD and antisocial personality disorder) in relatives of four groups of index children: children with attention deficit hyperactivity disorder (ADHD) and full, subthreshold, or no CD diagnoses and non-ADHD/non-CD control subjects. Results showed no interaction between gender and familiality across the four groups. Furthermore, there was no significant evidence of familiality of subthreshold CD. From a family genetic perspective, the diagnostic threshold for CD does not appear to differ by gender. The current results support the possibility that differential rates of CD reflect actual differences in rates of antisocial behavior across gender.
SAW-relevant material properties of langasite in the temperature range from 25 to 750 &#x00B0;C: New experimental results (2008)

The aim of this work is to determine the acoustical parameters of langasite up to the highest possible point of temperature. This paper presents measurements of transfer functions for delay lines on langasite at frequencies ranging from 150 MHz to 1 GHz, at temperatures from 25 to 750degC. Two cuts with Euler angles (0deg, 138.5deg, 26.6deg) and (0deg, 30.2deg, 26.6deg) have been studied. The devices were fabricated using langasite as substrate, with two different platinum (Pt) layer heights (45 nm and 75 nm), on a zirconium (Zr) adhesion layer (4 nm). A special signal processing algorithm utilizing cross-correlation was implemented in MATLAB and used for the analysis of measured data. The material parameters relevant for SAW devices, such as phase velocity, propagation loss, and electromechanical coupling coefficient, have been determined as a function of temperature.
Disinhibitory properties of β-carboline antagonists of benzodiazepine receptors: a possible therapeutic approach for senile dementia? (1989)

Conference Article| February 01 1989 Disinhibitory properties of β-carboline antagonists of benzodiazepine receptors: a possible therapeutic approach for senile dementia? M. SARTER; M. SARTER 1Department of Neuropsychopharmacology, Schering AG, P.O. Box 650311, D-1000 Berlin 65, Germany Search for other works by this author on: This Site PubMed Google Scholar D. N. STEPHENS D. N. STEPHENS 1Department of Neuropsychopharmacology, Schering AG, P.O. Box 650311, D-1000 Berlin 65, Germany Search for other works by this author on: This Site PubMed Google Scholar Biochem Soc Trans (1989) 17 (1): 81–83. https://doi.org/10.1042/bst0170081 Article history Received: August 08 1988 Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn Email Cite Icon Cite Get Permissions Citation M. SARTER, D. N. STEPHENS; Disinhibitory properties of β-carboline antagonists of benzodiazepine receptors: a possible therapeutic approach for senile dementia?. Biochem Soc Trans 1 February 1989; 17 (1): 81–83. doi: https://doi.org/10.1042/bst0170081 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsBiochemical Society Transactions Search Advanced Search Keywords: GABA, γ-aminobutyric acid, TBPS, t-butyl-bicyclophosphorothionate, DMCM, methyl 6,7-dimethoxy-4-ethylcarboline-3-carboxylate This content is only available as a PDF. © 1989 Biochemical Society1989 Article PDF first page preview Close Modal You do not currently have access to this content.
Complex Binding of the Embryonic Interferon, Ovine Trophoblast Protein-1, to Endometrial Receptors (1989)

Ovine embryos produce an interferon (IFN)-alpha II in significant quantities during early pregnancy. This IFN, previously termed ovine trophoblast protein-1 (oTP-1), is a 172-amino-acid polypeptide which has been suggested to be the causal agent in maternal recognition of pregnancy in the ewe. Here we report the binding of oTP-1 and a recombinant bovine IFN-alpha I1 (rBoIFN-alpha I1; 165-166 amino acids long) to membrane preparations from ovine uterine endometrium. Both oTP-1 and rBoIFN-alpha I1 competed with each other for receptor binding. Based on Scatchard analysis, [125I]oTP-1 binding was determined to be complex and resolvable into a high-affinity (Kd = 3.8 x 10(-11) M, 30 fmoles/mg protein) and a low affinity (Kd = 1.7 x 10(-10) M; 96 fmoles/mg protein) component. Conversely [125I]rBoIFN-alpha I1 bound to only a single high-affinity receptor (Kd = 6.1 x 10(-11) M; 174 fmoles/mg protein). Cross-linking experiments using disuccinimidyl suberate revealed that [125I]oTP-1 associated with membrane polypeptides of two molecular weight classes (Mr 100,000 and 70,000), and could be displaced from both with rBoIFN-alpha I1. In contrast, [125I]rBoIFN-alpha I1 cross-linked to only the 100,000 Mr membrane polypeptide. These data provide evidence that the binding parameters of oTP-1 and rBoIFN-alpha I1 to endometrial receptors are different.
Nano TRACTor: 1000 frames per minute slit SPECT for radiolabeled particle tracking (2015)

1872 Objectives Fast and precise in vivo tracking of nanoparticles or single cells could provide better understanding of drug and stem cell delivery. Present SPECT with traditional collimators lack sensitivity to achieve sufficiently high frame rates. In this project a multi-slit SPECT system with stationary detectors was designed to track nanoparticles with frame rates of 1000 frames per minute and a precision down to ~1 mm in a mouse-sized field of view (O25mmx100mm). Methods The SPECT system used has three large gamma cameras in a stationary triangular configuration. A 198Au nanoparticle of 6 µm diameter can be activated as high as ~37 kBq and is inert in an aqueous solution, which makes it very suitable for in-vivo particle tracking. To track such a particle, a collimator system with four slits in the axial direction and one slit in the transversal plane was designed with a geometric sensitivity higher than 0.5% per slit. Through each slit the particle gives a line-shaped response on a gamma camera. The position of the particle is found by solving the least squares solution of the intersection of the five planes defined by slits and the corresponding detector line responses. Simulations were made to optimise the design and evaluate the precision of this system. A preliminary system with a much larger field of view was used to track a rotating 99mTc source for initial validation. Results First measurements showed that the moving source could be tracked with a precision better than 1 mm at 600 frames per minute. Simulations demonstrate that one can track a 37 kBq 198Au nanoparticle with the optimised slit system up to 1000 frames per minute with a precision better than 1.4 mm (FWHM) in the axial direction and 0.4 mm (FWHM) in the transversal plane. Conclusions Our results indicate that Nano TRACTor is capable of tracking single radiolabeled particles at extremely high frame rates and a resolution close to a millimeter in small animals. This may open many new possibilities for e.g. nanoparticle and stem cell imaging.
Polyhalogenoallenes. Part IV. Thermal co-dimerisation of tetrafluoroallene with hexafluorobut-2-yne (1966)

Reaction of tetrafluoroallene with hexafluorobut-2-yne at 80—85° under autogenous pressure in the presence of free-radical scavengers yields, as major product, perfluoro-(1,2-dimethyl-3-methylenecyclobutene), the 19F nuclear magnetic resonance spectrum of which is discussed.
Microemulsion Liquid Crystal Templates for Highly Ordered Three-Dimensional Mesoporous Silica Monoliths with Controllable Mesopore Structures (2004)

Nanostructure composite silica monoliths (HOM-n) with three-dimensional (3-D) structures and controllable pore size were fabricated by using microemulsion lyotropic liquid crystal mesophase as templates under acidic conditions. By addition of alkanes with different molecular size (C6-C19 alkyl chains) into the primary lyotropic liquid crystal mesophase of Brij 56 (C16EO10), quaternary microemulsion liquid crystal phases formed and the mesophase topology of the surfactant was significantly enhanced with 3-D structures. Hydrocarbon molecular size and the degree of solubilization significantly influenced the amphiphilic phase behavior and the mesopore morphological structure. The phase transitions between the different cubic symmetries could be controlled by using a different solubilizing agent in the microemulsion phases of Brij 56 amphiphile. Thereby, the phase transition of primary liquid crystal mesophases in the microemulsion systems were used to fabricate well-defined highly ordered mesoporous silica monoliths HOM-n, including hexagonal P6mm (HOM-2), 3-D hexagonal P63/mmc (HOM-3), primitive-centered cubic Pn3m (HOM-7), Pm3n (HOM-9), and Pm3m (HOM-4) symmetries and body-centered cubic Im3m (HOM-1), bicontinuous cubic Ia3d (HOM-5), and face-centered cubic Fm3m (HOM-10) materials. In these systematic trends, the transitions were primarily governed by the interfacial curvature surface of the amphiphile aggregates. The interactions between alkanes and aggregates substantially influenced the interfacial surface curvatures of micelles, thereby affecting the preferable mesophase structures. However, the primitive cubic (Pm3n) and face-centered cubic (Fm3m) monoliths were the most stable phases among all mesophases, indicating that surfaces with high interfacial curvature were obtained by the addition of long hydrocarbon chain lengths (C10-C19 range). The addition of short lengths, hexane (C6) and heptane (C7), to the aggregate did not significantly affect the shape geometry of the phases, with the exception of the microemulsion lamellar phases formed in the 2-D hexagonal silica monoliths (HOM-2). Our results show that domains with highly curved interfaces were favored in these microemulsion systems. A tailored pore size was obtained within the transition between the 3-D phases with all mesophases. The extent of transition between the phases with enlarged pore dimensions was further studied by varying the amount of solubilizing agent in the microemulsion composition. Large 3-D monoliths of millimeter-sized particles had a wide range of uniform pore size between 30 and 80 Å, high surface area up to 900 m2/g, and thick walls of about 100 Å. Such properties will allow a wide range of mesoscopic applications.
Statistical Preconditioning and Quantitative Imaging for Electrical Impedance Tomography (2013)

We present a summary on the background of the EIT problem and discuss at length our computational methods to solve both the forward and inverse problems.Computed examples are discussed in detail to demonstrate the effectiveness of the inner-outer algorithm and the simulated high sensitivity and specificity of the method.
Role of Pseudomonas aeruginosa Peptidoglycan-Associated Outer Membrane Proteins in Vesicle Formation (2012)

Gram-negative bacteria produce outer membrane vesicles (OMVs) that package and deliver proteins, small molecules, and DNA to prokaryotic and eukaryotic cells. The molecular details of OMV biogenesis have not been fully elucidated, but peptidoglycan-associated outer membrane proteins that tether the outer membrane to the underlying peptidoglycan have been shown to be critical for OMV formation in multiple Enterobacteriaceae. In this study, we demonstrate that the peptidoglycan-associated outer membrane proteins OprF and OprI, but not OprL, impact production of OMVs by the opportunistic pathogen Pseudomonas aeruginosa. Interestingly, OprF does not appear to be important for tethering the outer membrane to peptidoglycan but instead impacts OMV formation through modulation of the levels of the Pseudomonas quinolone signal (PQS), a quorum signal previously shown by our laboratory to be critical for OMV formation. Thus, the mechanism by which OprF impacts OMV formation is distinct from that for other peptidoglycan-associated outer membrane proteins, including OprI.
Thermal management of a micro-display engine assembly (2004)

This paper presents the results of a thermal solution for a tiled Liquid Crystal on Silicon (LCoS) based micro display system. The system consisted of three silicon devices that were precision cut and tiled to form a single seamless to the edge display unit. The maximum allowable displacement between the edges of the silicon tiles and relative displacements between the tiles has to be tightly controlled to meet the system performance requirements. These requirements on displacement necessitated that the temperature gradients during the worst case operating conditions be well understood and quantified. The system design was selected such that the relative displacement between the tiles is kept to a minimum. A plate-finned heat sink in impingement mode (fan-sink) was selected, and tested experimentally. High thermal performance phase change material and thermal grease were selected and tested experimentally as thermal interface materials. Uncertainty analysis was carried out for each experiment. Analytical and numerical analyses were carried out as part of the material selection and optimization process for the parametric study of the micro-display engine assembly.
Analysis of Core Plasma Heating by Relativistic Electrons in Fast Ignition (2003)

To investigate core plasma heating in fast ignition, a relativistic Fokker-Planck code for fast electrons is developed in a one-dimensional planar coordinates system. It is found that in dense plasmas, the Joule heating is much smaller than the heating through Coulomb interactions. In the latter energy deposition process, the long-range collective effect is comparable to that of binary electron-electron collisions. Moreover, on the basis of coupled transport-hydrodynamic simulations in one-dimensional planar geometry, the core heating process for an ignition-experiment-grade compressed core (ρR = 0.3 g/cm2) is examined, and a possibility of evaluation of burn history from the neutron spectrum is shown. It is shown that a relatively low energy component (E0 ≤ 1 MeV) of electron beams plays an important role for effective core heating in fast ignition.