gebhart/patrepeval huggingface dataset:
Excitation energy transfer between inequivalent chromium(III) dimers in [(NH<sub>3</sub>)<sub>5</sub>CrOHCr(NH<sub>3</sub>)<sub>5</sub>]Cl<sub>5</sub>·H<sub>2</sub>O (1986)

Single crystals of the title compound were studied by optical absorption and luminescence spectroscopy in the region of 4A2 → 2E excitations. Zeeman, MCD and MCPL spectra were also recorded. Site-selective and time-resolved luminescence and excitation spectra provided information about the transfer of excitation energy. Exchange splitting patterns in the ground and excited state were obtained separately for the two inequivalent sets of dimers A and B in the crystal, and the corresponding exchange parameters were determined. The molecular orientations of the dimer units were derived from the spectroscopic data. The N-H stretching frequencies were found to play the major role as accepting modes in a multiphonon relaxation process. Numerical values were obtained for the rates of energy transfer between the sets A and B in the temperature range 1·5–100 K. They could be quantitatively accounted for by a one-phonon assisted electric dipole-dipole mechanism involving the 5A1 ↔ 5B1 dimer transitions.
Low use of neuroleptic drugs in the treatment of psychotic major depression (1997)

These findings suggest that many patients with psychotic major depression referred for ECT receive inadequate pharmacotherapy because of either the absence or the inadequate use of neuroleptic medication.
Suppression of the hot carrier effect in designing LATID MOS devices based on a new substrate current model (2002)

The gate-and-drain fully-overlap LATID (Large-Tilt-Angle Implanted Drain) structure has been proposed recently and been used in submicron MOS device design to suppress the spacer-induced degradation and improve the device current drivability. So far, none has been provided to study quantitatively the hot carrier effect for various device process conditions such as the implantation of n/sup -/ dosage and angle. A closed form expression of a new and accurate substrate current model is proposed based on the effective electric field concept by considering the overall (2D) electric field distribution within devices, which can be used to explain quantitatively and for predicting the substrate currents of LATID MOS devices. Its utilization in designing a hot carrier resistant device is demonstrated.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Cartilage oligomeric matrix protein is differentially expressed in human subcutaneous adipose tissue and regulates adipogenesis (2018)

We confirmed that COMP is an ECM protein which is differentially expressed between subcutaneous abdominal and gluteal AT. Despite its depot-specific expression pattern, however, AT COMP mRNA levels and plasma COMP concentration correlated positively with overall obesity but not body fat distribution. Exogenous COMP enhanced adipogenesis. These data identify COMP as a novel regulator of AT and highlight the importance of the ECM to AT biology.
Isomerisation, déshydration et réduction du méthyl‐4 dioxa‐1,6 spiro[4,5]decanol‐4. Obtention de précurseurs ou d'isomères de phéromones de guêpe (1983)

Abstract Le mélange des stéréosiomères des dioxaspirannols 1 obtenu par photolyse de l'(oxo‐3 n ‐butyloxy)‐2 tétra‐hydropyranne, peut ětre enrichi par des méthodes chimiques en isomère cis (chlorure d'aluminium/acétate d'aluminium) ou trans (anhydride acétique puis hydrolyse). La thermolyse des acétates 2 ou des xanthates 5 conduit à un composé furannique 4 , précurseur éventuel d'une dioxaspirolactone. La réduction des xanthates 5 donne les méthyl‐4 dioxaspirodécanes 8 , isomères de position d'une phéromone de guěpe.
Characterization of a porcine intestinal epithelial cell line for influenza virus production (2012)

We have developed a porcine intestine epithelial cell line, designated SD-PJEC for the propagation of influenza viruses. The SD-PJEC cell line is a subclone of the IPEC-J2 cell line, which was originally derived from newborn piglet jejunum. Our results demonstrate that SD-PJEC is a cell line of epithelial origin that preferentially expresses receptors of oligosaccharides with Sia2-6Gal modification. This cell line is permissive to infection with human and swine influenza A viruses and some avian influenza viruses, but poorly support the growth of human-origin influenza B viruses. Propagation of swine-origin influenza viruses in these cells results in a rapid growth rate within the first 24 h post-infection and the titres ranged from 4 to 8 log(10) TCID(50) ml(-1). The SD-PJEC cell line was further tested as a potential alternative cell line to Madin-Darby canine kidney (MDCK) cells in conjunction with 293T cells for rescue of swine-origin influenza viruses using the reverse genetics system. The recombinant viruses A/swine/North Carolina/18161/02 (H1N1) and A/swine/Texas/4199-2/98 (H3N2) were rescued with virus titres of 7 and 8.25 log(10) TCID(50) ml(-1), respectively. The availability of this swine-specific cell line represents a more relevant substrate for studies and growth of swine-origin influenza viruses.
Method for calculation of compressible laminar boundary layer with axial pressure gradient and heat transfer (1954)

Report presenting a rapid and sufficiently accurate method of determining laminar-boundary-layer characteristics in flow with a given free-stream Mach number and given velocity distribution at the edge of the boundary layer. The method can be easily applied to flow with zero pressure gradient for any constant Prandtl number of the order of unity and any given temperature distribution along wall.
Gray Tracking Correction for TFT-Lcds (2002)

The consistency of the white point with the input gray level is referred in the world of display technology as gray tracking. Gray tracking is an issue for Twisted Nematic (TN) TFT-LCD screens which typically show a bluish shift of the white point when the gray level decreases. This paper discusses some causes of the colorcast in TN displays and proposes a method for correcting it by using the existing video card look-up tables (VLUT) in the graphic controller or in the panel itself. The correction process performs the gamma correction and the gray tracking correction simultaneously. The gray tracking correction uses the luminance and the chrominance information of the R, G, B channels. For a single VLUT entry, for the corresponding output value in one channel (G for example), the method computes the output values for the other two channels (R and B respectively) such that, the resulted gray has the minimum chromatic difference to the desired white point of the display. The method proves to remove the colorcast in the TN TFT-LCD screens. The method is general and can be applied to any display technology.
PROCESS ENGINEERING REPORT ON THORIUM SEMIWORKS PLANT FOR THE FEED MATERIALS PRODUCTION CENTER, FERNALD, OHIO. Job No. 3542 (1952)

This technical report presents the process design for the thorium semi-works plant which will be located at the Feed Materials Production Center, Fernald, Ohio. It contains the process information required for the layout and detailed mechanical design of the thorium plant.
High-risk regions and outbreak modelling of tularemia in humans (2016)

Sweden reports large and variable numbers of human tularemia cases, but the high-risk regions are anecdotally defined and factors explaining annual variations are poorly understood. Here, high-risk regions were identified by spatial cluster analysis on disease surveillance data for 1984-2012. Negative binomial regression with five previously validated predictors (including predicted mosquito abundance and predictors based on local weather data) was used to model the annual number of tularemia cases within the high-risk regions. Seven high-risk regions were identified with annual incidences of 3·8-44 cases/100 000 inhabitants, accounting for 56·4% of the tularemia cases but only 9·3% of Sweden's population. For all high-risk regions, most cases occurred between July and September. The regression models explained the annual variation of tularemia cases within most high-risk regions and discriminated between years with and without outbreaks. In conclusion, tularemia in Sweden is concentrated in a few high-risk regions and shows high annual and seasonal variations. We present reproducible methods for identifying tularemia high-risk regions and modelling tularemia cases within these regions. The results may help health authorities to target populations at risk and lay the foundation for developing an early warning system for outbreaks.
Photo-Electrochemical Hydrogen Generation from Inverted Metamorphic Multijunction III-Vs (2017)

Our goal is to improve solar-to-hydrogen (STH) efficiency from just over 10% to over 20% via novel tandem semiconductor materials and configurations. Our primary focus is to develop inverted metamorphic multijunction (IMM) III-V semiconductors that have bandgaps optimized for water splitting. We will also discuss measurement challenges in appraising STH efficiency, some of which are specific to tandem absorbers. Using more stringent measurement standards, we have confirmed 16.2% STH on our most advanced IMM devices.
Performance Analysis for Transmit-Beamforming with Finite-Rate Feedback (2004)

Abstract — Transmit beamforming achieves optimal performance in systems with multiple transmit- and single receive- antennas, when perfect channel knowledge is available at the transmitter. In practical systems where the feedback link can only convey a finite number of bits, the beamformer design has been extensively investigated from both the outage probability and the average signal to noise ratio (SNR) perspectives. In this paper, we study the symbol error rate (SER) for transmit beamforming with finite-rate feedback. We derive a SER lower bound, which is tight for good beamformer designs. Comparing this bound with the SER of the ideal case, we quantify the power loss due to the finite rate constraint, across the whole SNR range. I.
The Hazard and Origin of the Well-bore type collapse in the coal mined-out area of Western Hills,Beijing (2002)

In the geological hazard survey of Western Hills of Beijing Municipality, which began in the 1980s,one of the main arguments is the origin of well bore type coll apse Based on the geological,hydrological and climatic conditions of the Western Hills,we analyzed the geological features of well bore type collapse We proposed that the origin of well bore type collapse is chiefly related to the mined out of underground coal beds Meanwhile,the downward seepage of surface water and the mining induced earthquake are two important factors to induce the collapse
Clinical Profile of the Orexin Receptor Antagonist Suvorexant for the Treatment of Insomnia in Phase-3 Clinical Trials (PL1.001) (2014)

BACKGROUND: Night-time administration of orexin receptor antagonists is hypothesized to dampen orexin-mediated wakefulness, facilitating sleep. Here, we provide an overview of the clinical profile of suvorexant, an investigational orexin receptor antagonist for the treatment of insomnia, in Phase-3 trials. DESIGN/METHODS: The Phase-3 program comprised two 3-month confirmatory efficacy trials (Trial-1 and Trial-2) and a 1-year safety trial (Trial-3). All trials were randomized, double-blind, placebo-controlled, parallel-group, studies in non-elderly (18-64 years) and elderly (蠅65 years) patients with insomnia. Doses of 40mg (non-elderly) and 30mg (elderly) were evaluated in all three trials; 20mg (non-elderly) and 15mg (elderly) were also evaluated in Trials-1&2. Elderly dose-adjustments were made to match non-elderly exposures. In Trials-1&2, efficacy was assessed at Week-1, Month-1, and Month-3 by subjective endpoints (reported on a patient daily diary) of total-sleep-time (sTST), time-to-sleep onset (sTSO), and wake-time-after-sleep-onset (sWASO), and at Night-1, Month-1, and Month-3 by polysomnographic (PSG) endpoints of Latency-to-onset-of-Persistent-Sleep (LPS) and Wakefulness-After-persistent Sleep-Onset (WASO). In Trial-3, efficacy was assessed over 1-year and in a 2-month relapse prevention phase by sTST, sTSO, and sWASO. RESULTS: The number of patients randomized was 1021 in Trial-1, 1019 in Trial-2, and 781 in Trial-3. In Trial-1 and Trial-2, suvorexant 40/30mg and 20/15mg were significantly superior to placebo on most subjective and PSG endpoints at Night-1/Week-1, Month-1 and Month-3. In both trials, the magnitude of improvement appeared dose-related. In Trial-3, suvorexant 40/30mg was superior to placebo at each month over 1-year. In the relapse prevention phase of Trial-3, insomnia symptoms returned after suvorexant discontinuation, suggesting the improvement over the previous year was attributable to suvorexant. Suvorexant was generally well-tolerated in all three trials, without evidence of clinically important rebound or withdrawal upon discontinuation. CONCLUSIONS: Suvorexant improved sleep onset and maintenance over 3-months in two confirmatory Phase-3 trials and over 1-year in a long-term trial, and was generally well-tolerated without evidence of clinically important rebound or withdrawal effects following discontinuation. Study Supported by: Merck
RfaH enhances elongation of Escherichia coli hlyCABD mRNA (1996)

Escherichia coli hlyCABD operons encode the polypeptide component (Hly A) of an extracellular cytolytic toxin, as well as proteins required for its acylation (HlyC) and sec-independent secretion (HlyBD). Previous reports suggested that the E. coli protein RfaH is required for wild-type hemolysin expression, either by positively activating hly transcript initiation (M. J. A. Bailey, V. Koronakis, T. Schmoll, and C. Hughes, Mol. Microbiol. 6:1003-1012, 1992) or by promoting proper insertion of hemolysin export machinery in the E. coli outer membrane (C. Wandersman and S. Letoffe, Mol. Microbiol. 7:141-150, 1993). RfaH is also required for wild-type levels of mRNA transcribed from promoter-distal genes in the rfaQ-K, traY-Z, and rplK-rpoC gene clusters, suggesting that RfaH is a transcriptional antiterminator. We tested these models by analyzing the effects of rfaH mutations on hlyCABD mRNA synthesis and decay, HlyA protein levels, and hemolytic activity. The model system included a uropathogenic strain of E. coli harboring hlyCABD on the chromosome and E. coli K-12 transformed with the hlyCABD operon on a recombinant plasmid. Our results suggest that RfaH enhances hlyCABD transcript elongation, consistent with the model of RfaH involvement in transcriptional antitermination in E. coli. We also demonstrated that RfaH increases toxin efficacy. Modulation of hemolysin activity may be an indirect effect of RfaH-dependent E. coli outer membrane chemotype, which is consistent with the model of lipopolysaccharide involvement in hemolytic activity.
From the Guest Editors - Industrial robotics applications and industry-academia cooperation in Europe (2005)

Presents the guest editorial for this issue of the publication.
Identical Strength of the T Cell Responses against E2, nsP1 and Capsid CHIKV Proteins in Recovered and Chronic Patients after the Epidemics of 2005-2006 in La Reunion Island (2013)

To characterize the immunity developed by patients infected by chikungunya virus (CHIKV), we studied the intensity and specificity of CHIKV-specific T cells mediated responses in chronic and recovered patients at 12 to 24 months post-infection. T cells were challenged in vitro against CHIKV synthetic peptides covering the length of three viral proteins, capsid, E2 and nsP1 proteins as well as all inactivated virus particles. Cytokine production was assessed by ELISPOT and intracellular labeling. T cells producing IFN-γ were detected against CHIKV in 85% patient's cells either by direct ELISPOT assay (69% of patients) or after expansion of memory T cells allowing the detection of both CD4 and CD8 specific-T cells in 16% additional cases. The IFN-γ response was mainly engaged in response to nsP1 or E2 (52% and 46% cases, respectively) but in only 27% cases against the capsid. The anti-E2 response represented half the magnitude of the total CHIKV IFN-γ production and was mainly directed against the C-terminal half part of the protein. Almost all patients had conserved a T cell specific response against CHIKV with a clear hierarchy of T cell responses (CD8 > CD4) engaged against E2 > nsP1 > capsid. More importantly, the intensity of responses was not significantly different between recovered and chronic patients. These findings constitute key elements to a better understanding of patient T cell immunoreactivity against CHIKV and argue against a possible defect of T cell immunoresponse in the chronicity post-CHIKV infection.
Protection against Respiratory Syncytial Virus by a Recombinant Newcastle Disease Virus Vector (2006)

Respiratory syncytial virus (RSV) is a major cause of severe lower respiratory tract disease in infants and the elderly, but no safe and effective RSV vaccine is yet available. For reasons that are not well understood, RSV is only weakly immunogenic, and reinfection occurs throughout life. This has complicated the search for an effective live attenuated viral vaccine, and past trials with inactivated virus preparations have led to enhanced immunopathology following natural infection. We have tested the hypothesis that weak stimulation of innate immunity by RSV correlates with ineffective adaptive responses by asking whether expression of the fusion glycoprotein of RSV by Newcastle disease virus (NDV) would stimulate a more robust immune response to RSV than primary RSV infection. NDV is a potent inducer of both alpha/beta interferon (IFN-alpha/beta) production and dendritic cell maturation, while RSV is not. When a recombinant NDV expressing the RSV fusion glycoprotein was administered to BALB/c mice, they were protected from RSV challenge, and this protection correlated with a robust anti-F CD8+ T-cell response. The effectiveness of this vaccine construct reflects the differential abilities of NDV and RSV to promote dendritic cell maturation and is retained even in the absence of a functional IFN-alpha/beta receptor.
Holographic patient tracking after bed movement for augmented reality neuronavigation using a head-mounted display (2021)

This first report shows a proof of principle of intraoperative patient tracking using a standalone holographic neuronavigation system. The navigation accuracy should be further optimized to be clinically applicable. However, it is likely that this technology will be incorporated in future neurosurgical workflows because the system improves spatial anatomical understanding for the surgeon.
Effect of Leaf Color, Chlorohyll Concentration, and Temperature on Photosynthetic Rates of Isogenic Barley Lines<sup>1</sup> (1972)

Abstract Leaf color and chlorophyll content may affect canopy temperature and, indirectly, plant metabolism and dry matter production. Photosynthesis (P), light saturation, specific leaf weight (SLW, mg/cm 2 ), and chlorophyll content (mg/dm 2 ) of barley lines isogenic for color were measured over a range of temperatures using plants grown in one field and two greenhouse experiments. In the first greenhouse experiment P of all lines did not differ at temperatures of 20, 15, and 30 C. Differences in P occurred among three cultivars, but the differences between isogenic pairs were significant for the cultivar ‘Colsess’ only. In the second greenhouse experiment P was highest at 25 and 30 C, slightly lower at 35 C, and lowest at 15 and 20 C. P on a leaf area basis differed only for the isogenes of ‘Betzes’ but on a unit of chlorophyll basis was significantly higher for each pale green or golden member of an isogenic pair. Pale barley leaf blades had a higher light saturation point than normal green leaf blades. SLW was greater for the green member of one isogenic pair but not significantly different between members of other pairs. Highest P of field grown plants occurred at 25 C. Green members of isogenic pairs had significantly higher P than pale green or golden members. SLW of field grown green isogenes was significantly higher than that of pale green or golden isogenes and higher than SLW of plants grown in the greenhouse.
Read-Once Threshold Formulas, Justifying Assignments, and Generic Transformations (1991)

We present a membership query (i.e. interpolation) algorithm for exactly identifying the class of read-once formulas over the basis of boolean threshold functions. Using a generic transformation from [Angluin, Hellerstein, Karpinski 89], this gives an algorithm using membership and equivalence queries for exactly identifying the class of read-once formulas over the basis of boolean threshold functions and negation. We also present a a series of generic transformations that can be used to convert an algorithm in one learning model into an algorithm in a different model.
Quantitative determination of transient species in atmospheric pressure flames with a picosecond laser diagnostic (1986)

Quantitative fluorometry of transient combustion species is complicated by the need for information on the composition and quenching rates of the entire system. Saturated fluorometry is one approach to this problem. An alternative, nonsaturating fluorometric method will be illustrated for OH and NH 2 at 1 atm. Projections of sensitivity at elevated pressures will be derived from this data. The measurement technique utilizes low power (nanojoule) picosecond pulses at megahertz repetition rates to achieve a quantitative measure of species concentration that is independent of quenching environment. Direct measurement of quenching rates as fast as 2 × 10 10 /s are also possible with the instrumentation developed. The technique involves a noncommercial narrow gated photon counting detection system which is synchronous with a cavity dumped, synch-pumped dye laser. These high repetition rate methods have not previously been applied to the field of combustion diagnostics.
ENGINEERING, DESIGN, AND PROCESS DEVELOPMENT SECTION Activation of Carbons (1954)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTENGINEERING, DESIGN, AND PROCESS DEVELOPMENT SECTION Activation of CarbonsW. K. Lewis and A. B. MetznerCite this: Ind. Eng. Chem. 1954, 46, 5, 849–858Publication Date (Print):May 1, 1954Publication History Published online1 May 2002Published inissue 1 May 1954https://pubs.acs.org/doi/10.1021/ie50533a020https://doi.org/10.1021/ie50533a020research-articleACS PublicationsRequest reuse permissionsArticle Views69Altmetric-Citations7LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts