gebhart/patrepeval huggingface dataset:
Host Defensive, Immunological, and Microbiological Observations of an Early‐Onset Periodontitis Patient With Virus‐Associated Hemophagocytic Syndrome (1997)

Virus-associated hemophagocytic syndrome (VAHS) is a disorder characterized by benign generalized histiocytic proliferation and marked hemophagocytosis associated with systemic viral infection. An immunodeficiency which includes an extremely decreased leukocyte and platelet count together with abnormalities in the CD4/CD8 ratio are the most common features of VAHS. Here we report an early-onset periodontitis (EOP) patient with VAHS from the standpoint of host-parasite interaction to understand the effect of this systemic disorder which might possibly influence susceptibility to periodontal disease. The patient is a 16-year-old Japanese male clinically diagnosed as having generalized EOP with slight gingival inflammation and moderate bone loss. This patient manifested VAHS at 3 years of age, and then had an unusual 4 recurrences (at 5, 7, 11, and 14 years old). Laboratory tests conducted include: 1) complete blood analyses: 2) peripheral neutrophil functions (chemotaxis, phagocytosis, superoxide production, and adherence); 3) peripheral lymphocyte subpopulations and functions, T-cell proliferative activity and productivity of cytokines (interleukin-2 [IL-2], interferon gamma [IFN-gamma], and tumor necrosis factor alpha [TNF-alpha]); 4) serum cytokine levels (IL-1 beta, IL-2, soluble IL-2 receptor [sIL-2R], IL-4, IL-6, IFN-gamma, and TNF-alpha; 5) serum immunoglobulin G (IgG) antibody titers against periodontopathic bacteria; 6) serological human leukocyte antigen (HLA) typing; and 7) determination of bacterial flora of the periodontal pockets. The results indicated that the patient's neutrophil chemotaxis and random migration were below the normal range. In lymphocyte examinations, T-cell proliferative activity, IL-2, and IFN-gamma productivity were elevated. Serum IFN-gamma level was also significantly higher than normal range. No specific periodontopathic bacteria were predominant in the periodontal pockets, however, the serum IgG titer against Porphyromonas gingivalis was elevated throughout the examination period. It is suggested that VAHS might be a possible risk factor for periodontal disease, and hence may serve as a model in understanding the role of host defense mechanisms in the establishment of inflammatory periodontal disease.
Characterization of citrus pectin samples extracted under different conditions: influence of acid type and pH of extraction (2014)

Structural, and hence macromolecular, variations within the different citrus pectin samples were mainly related to their rhamnogalacturonan I contents and integrity, and, to a lesser extent, to the length of their homogalacturonan domains.
Synthesis of Polycyclic Nitrogen Heterocycles via Cascade Pd-Catalyzed Alkene Carboamination/Diels–Alder Reactions (2015)

Cascade Pd-catalyzed alkene carboamination/Diels-Alder reactions between bromodienes and amines bearing two pendant alkenes are described. These transformations generate 4 bonds, 3 rings, and 3-5 stereocenters to afford polycyclic nitrogen heterocycles with high diastereoselectivity.
Cardiac Effects of Experimental Intravenous Bone Marrow Cell Transplantation after Myocardial Infarction (2012)

Intravenous BMC-Tx led to less calcifying remodelling and a compensatory hypertrophy within the infarction area that probably contributes to functional recovery.
Removal of phenol from coupling of talc and peroxidase. Application for depollution of waste water containing phenolic compounds (1994)

Abstract The degradation of phenol by a combination of horseradish peroxidase/hydrogen peroxide in the presence of talc, a natural abundant and low cost mineral, was investigated. Adsorption of the reaction products on the talc effectively protected the biocatalyst against contamination by oxidative products, thereby prolonging its catalytic action and leading to almost complete elimination of phenols in aqueous media. Suitable conditions for depollution of waste water containing phenolic substances were developed after optimization of various parameters (type and amount of talc, reaction duration).
Microphonics and Lorentz Transfer Function Measurements on the SNS Cryomodules (2003)

As part of the acceptance tests, we have performed a number of measurements of microphonics levels and frequency spectra on the SNS cryomodules. These measurements are particularly important since those cryomodules may be used in the high-energy section of the RIA driver, a low-current CW accelerator. Measurements of the complete transfer functions between rf field modulation and cavity resonant frequency have also been performed.
Buried stressors in nitride semiconductors: Influence on electronic properties (2005)

An analysis is presented on the effect of the strain field originating from a subsurface stressor (point source of dilatation or a dilatating ellipsoidal inclusion) on the electronic properties of nitride semiconductors. With good accuracy, real quantum dots can be modeled as such stressors. We consider the following material structure design: a uniform semi-infinite GaN matrix with a buried stressor or a GaN matrix with a single (In,Ga)N quantum well, which is grown pseuodomorphically between the stressor and the free surface. We utilize isotropic elasticity to determine the strain field in the structures under investigation. We then apply a k∙p perturbation theory approach to examine the shifts of the conduction and valence band edges caused by the stressor. We find lateral confinement for electrons and holes, which can be proposed for the realization of strain-induced quantum dots in the quantum well.
Magneto-optic and converse magnetoelectric effects in a ferromagnetic liquid crystal (2014)

We have studied the response of ferromagnetic liquid crystals to external magnetic and electric fields, and compared it to the usual response of nematic liquid crystals (NLCs). We have observed effects, which are not present in a pure NLC and are a consequence of the coupling between the nematic director and the magnetization. The electro-optic effect, which is in the ferromagnetic phase the same as in the pure NLC, is accompanied by a converse magnetoelectric effect. The magneto-optic effect differs completely from the one observed in the pure NLC, where it is a quadratic effect and it only appears when a magnetic field larger than a critical field is applied perpendicular to the director. In the ferromagnetic NLC in addition to the response to the perpendicular field, there is also a qualitatively different response to the parallel field. Contrary to the pure NLC no critical field needs to be exceeded for the system to respond to a perpendicular field, but a critical field needs to be exceeded to observe a response to the field parallel to the director and antiparallel to the magnetization. The critical field is in this case two orders of magnitude smaller than the critical field of the magnetic Frederiks transition in the pure NLC. The experimental observations are well described by a simple macroscopic theory.
Inhibitory Effect of Heparin upon Histamine Release by Trypsin, Antigen, and Proteose. (1942)

Anaphylactic, trypsin, and peptone shock are closely related phenomena. The prominent symptoms are similar and the intravenous injection of antigen, trypsin, or proteose into intact animals has been shown to result in the liberation of significant amounts of histamine. It has also been shown that the addition of antigen, trypsin, or proteose to rabbits' blood (rendered incoagulable with heparin) leads to the release of histamine from cells to plasma. It is possible that the mechanisms of the release are the same in each case. A study of the effect of various agents in inhibiting or augmenting the release of histamine by the above substances suggests itself as a means of determining whether similar mechanisms are involved. Inasmuch as rabbits' blood can be divided into samples which can be considered identical in every respect, this tissue seems to provide an ideal medium for such studies.It has been shown that heparin is capable of inhibiting the proteolysis of various substrates by trypsin,, and we have found that heparin antagonizes the toxic effects of trypsin in intact animals. Consequently the present experiments were performed to determine whether heparin has an inhibitory effect upon the release of histamine by trypsin, and if so, to examine the effect of heparin upon the release of histamine by antigen and by proteose.Experimental. Blood was obtained from unanesthetized rabbits by cardiac puncture. Sufficient heparin was added to this blood to prevent clotting, a concentration of 0.02%. Each blood sample was divided into 3 tubes. Saline was added to the first tube; specific antigen, trypsin, or proteose was added to the second tube; and specific antigen, trypsin. Or proteose plus additional heparin, a final concentratin of 0.12% was added to the third tube.
Application of machine learning and visualization of heterogeneous datasets to uncover relationships between translation and developmental stage expression of<i>C. elegans</i>mRNAs (2005)

The relationships between genes in neighboring clusters in a self-organizing map (SOM) and properties attributed to them are sometimes difficult to discern, especially when heterogeneous datasets are used. We report a novel approach to identify correlations between heterogeneous datasets. One dataset, derived from microarray analysis of polysomal distribution, contained changes in the translational efficiency of Caenorhabditis elegans mRNAs resulting from loss of specific eIF4E isoform. The other dataset contained expression patterns of mRNAs across all developmental stages. Two algorithms were applied to these datasets: a classical scatter plot and an SOM. The outputs were linked using a two-dimensional color scale. This revealed that an mRNA's eIF4E-dependent translational efficiency is strongly dependent on its expression during development. This correlation was not detectable with a traditional one-dimensional color scale.
Hall magnetohydrodynamics simulations of end-shorting induced rotation in field-reversed configurations (2007)

End-shorting of the open field lines that surround a field-reversed configuration (FRC) is believed to contribute to its observed rotation. In this study, nonlinear extended magnetohydrodynamics (MHD) simulations were performed that detail the end-shorting process and the resulting spin-up of the FRC. The tangential component of the electric field ET is set to zero at the axial boundaries in an extended MHD model that includes the Hall and ∇Pe terms. This shorting of the electric field leads to the generation of toroidal fields on the open field lines, which apply a torque leading to a rotation of the ions on the open field lines. The FRC then gains angular momentum through a viscous transfer from the open field line region. In addition, it is shown that spin-up is still induced when insulating boundaries are assumed.
[The disappearance of CD20 positive lymphocytes in the pleural effusion after intrapleural application of rituximab]. (2007)

A 63 year old woman with non-Hodgkin lymphoma presented with unilateral pleural effusion, which when aspirated revealed CD19 and CD20 positive malignant cells. Prior to this, the patient had received several lines of chemotherapy (CHOP, VAD, FED) with no effect on pleural effusion. Repeated percutaneous drainage procedures were unable to control the effusion either. Rituximab was therefore instilled in a dose escalating manner via repeated pleurocenteses. Fifty days after the application of rituximab, pleural effusion was still present but reduced in size. Flow cytometry and immunocytochemistry performed on the same day showed CD19 positive cells which were lacking CD20 epitope, which could be explained by either engagement or destruction of the CD20 epitope upon interaction with rituximab making the detection of the CD20 molecule impossible by routine flow cytometry. What is especially interesting is the fact that even 50 days after the application of rituximab intrapleurally no new CD20 positive cells could be found in the pleural effusion by immunochemistry or flow cytometry, opening an interesting issue concerning the length of rituximab's activity when applied locally. Although our patient had no adverse effects, further analysis of rituximab's activity and safety when applied intrapleurally is warranted.
Anterolateral thigh flap – a new workhorse for plastic reconstruction surgeons (2004)

The antero‐lateral thigh (ALT) flap was originally reported by Song et al. in 1984. It is only in the last 5 to 6 years, however, that the ALT flap has become established as a highly versatile “work‐horse”, in surgical reconstruction. Our experience in various reconstructions with ALT flap in various parts of the body is discussed. Twenty seven patients with 17 male and 10 female were studied. Their age ranged from 2 to 78. Fifteen ALT flaps were used for head and neck reconstruction (11 in head region, four in neck region). 10 for limbs reconstruction (five in upper limb, five in lower limb) and two for trunk reconstruction. Out of the 27 ALT flaps, there were 24 free flaps and five pedicle flaps. There was no morbidity associated with all the 27 operations. Nine patients had primary reconstruction after tumor excision. Eighteen ALT flaps were used to reconstruct tissue with previous surgery or radiotherapy. There was no flap failure. There were two wound infection which treated conservatively with dressing. Anterolateral lateral thigh flap is a reliable flap for various reconstruction with minimal morbidity.
A Novel Luciferase Assay For Sensitively Monitoring Myocilin Variants in Cell Culture (2016)

Fusion of eGLuc2 to MYOC does not significantly change the behavior of MYOC. This newly developed MYOC reporter system can be used to study engineered MYOC variants and potentially to identify modulators of MYOC secretion and function.
Production control (2002)

Production control is a rich source of potential data mining applications. Gathering and cleaning the data are relatively easy. Organizations own their own production data so there are almost no legal and privacy issues. Cost justification and return on investment estimates are easy to do because organizations have a long history of setting up administrative procedures to optimize production processes. On the other hand, the penetration of data mining in this segment of industry is small. This is partly caused by the success of traditional operations: research techniques that have already removed a lot of the low-hanging fruit. Another explanation is the specialized nature of production processes in various organizations. We distinguish between horizontal and vertical data mining applications. Horizontal applications can be transferred from one production industry to another. In the coming years, we expect the emergence of standard horizontal data mining solutions based on standard ERP platforms. Vertical applications are restricted to one organization or a very small group of companies. There is an abundance of examples of successful applications of vertical data mining. Although these individual applications are too specific to be generalized, one can distinguish classes of application paradigms that can be used across industry to solve similar types of data mining problems.
Synthesis and Evaluation of a Pleurotin Analog (1993)

Abstract The photoenolization/Diels-Alder sequence provides a direct preparation of quinone 2 which exhibited activity against SR leukemia and colon cancers.
ChemInform Abstract: A New Chemical Method for Synthesizing and Recycling Acyl Coenzyme A Thioesters. (1991)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
High-Speed GMAW and Laser GMAW Hybrid Welding of Steel Sheet (2009)

Arc welding is the most widely used set of joining technologies in industry today.\nThe automotive tier supplier network and light manufacturing are significant users of\narc welding, particularly gas metal arc welding (GMAW) and pulsed GMAW\n(GMAW-P). For sheet metal welding the majority of welds are single pass fillet\nwelds on T-butt, lap, or edge joints. A fundamental problem and limitation to the use\nof higher travel speeds in GMAW is the phenomenon of weld bead humping, a weld\nprofile defect with a wavelike profile to the weld bead that has peaks and troughs in\nthe longitudinal direction. Cont/d.
Electronic and molecular structure of simple bicyclopropyls. Photoelectron spectroscopy and model calculations (1982)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTElectronic and molecular structure of simple bicyclopropyls. Photoelectron spectroscopy and model calculationsJens Spanget-Larsen, Rolf Gleiter, and Klaus GubernatorCite this: J. Org. Chem. 1982, 47, 16, 3082–3089Publication Date (Print):July 1, 1982Publication History Published online1 May 2002Published inissue 1 July 1982https://pubs.acs.org/doi/10.1021/jo00137a011https://doi.org/10.1021/jo00137a011research-articleACS PublicationsRequest reuse permissionsArticle Views49Altmetric-Citations10LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
第1部 文部科学省研究開発学校 研究開発実施報告 平成19年度(延長第2年次) : 中等教育における科学を支える「リテラシー」の育成を核とする教育課程の開発 (2008)

2 1AJ ( 7 0)
HIRF Penetration Into Simplified Fuselage Using a Reverberation Chamber Approach (2005)

In this paper, high-intensity radiated fields (HIRF) penetration into aircraft fuselage is studied using a reverberation chamber approach. A mode-stirrer is constructed and placed inside a simplified scale fuselage model. Measurements of the penetrating field are performed for different mode-stirrer positions. The collected sets of data are statistically processed and their probability distributions are investigated. Goodness-of-fit tests are performed between data empirical cumulative density functions and existing theoretical probability models which govern the electromagnetic field variations inside reverberation chambers.
The Development of a ɛ-Polycaprolactone Scaffold for Central Nervous System Repair (2012)

Potential treatment strategies for the repair of spinal cord injury (SCI) currently favor a combinatorial approach incorporating several factors, including exogenous cell transplantation and biocompatible scaffolds. The use of scaffolds for bridging the gap at the injury site is very appealing although there has been little investigation into the central nervous system neural cell interaction and survival on such scaffolds before implantation. Previously, we demonstrated that aligned microgrooves 12.5-25 μm wide on ε-polycaprolactone (PCL) promoted aligned neurite orientation and supported myelination. In this study, we identify the appropriate substrate and its topographical features required for the design of a three-dimensional scaffold intended for transplantation in SCI. Using an established myelinating culture system of dissociated spinal cord cells, recapitulating many of the features of the intact spinal cord, we demonstrate that astrocytes plated on the topography secrete soluble factors(s) that delay oligodendrocyte differentiation, but do not prevent myelination. However, as myelination does occur after a further 10-12 days in culture, this does not prevent the use of PCL as a scaffold material as part of a combined strategy for the repair of SCI.
White matter integrity as a mediator in the relationship between dietary nutrients and cognition in the elderly (2016)

Our study suggests that older adults consuming more polyunsaturated fatty acids and vitamin E rich foods had better white matter integrity, and that maintaining white matter microstructural integrity might be a mechanism for the beneficial role of diet on cognition. Ann Neurol 2016;79:1014-1025.
Efficient chirality transcription utilizing a cerium(IV) double decker porphyrin: a prototype for development of a molecular memory system (1999)

A cerium(IV) double decker porphyrin 2 bearing two pairs of 4-pyridyl groups and two pairs of 3,5-dimethoxyphenyl groups was synthesized. In the presence of chiral dicarboxylic acid guests with a two carbon spacer [e.g., (1R,2R)-cyclohexane-1,2-dicarboxylic acid and Boc-L-aspartic acid] 2 gave a CD-active species. The plots of the CD intensity vs. the guest concentration showed a sigmoidal curvature, a sign of homotropic, positive allosterism. Analysis according to the Hill equation indicated that the guests were bound autoacceleratively. Even after the chiral guests were removed by the addition of excess pyridine, 2 remained CD-active because of its inherent chirality. Thereafter, the CD intensity decreased very slowly as a result of internal rotation of the porphyrin subunits. Thermodynamic analysis of this racemization process gave ΔG ‡298 = 23.0 kcal mol–1, ΔH ‡298 = 18.1 kcal mol–1 and ΔS ‡298 = –16.4 cal mol–1 K–1. Observations and calculations indicate that the chiral memory can be preserved for 3 days at 0 °C and for one year at –37 °C. In conclusion, this is a rare artificial system for which a homotropic, positive allosterism is observable and in which the guest chirality is transcribed and stored.
Measurement of the width of the inverted Lamb dip in H2CO at 3.51 μm (1979)

The width of the inverted Lamb dip in H2CO at 3.51 μm [51,5 (ground state) →60,6(v5=1)] was measured by using a low-noise He-Xe laser in an axial magnetic field as the light source. To measure the dip width it was necessary to determine first the range of the magnetic field strength and the maximum frequency deviation of the laser frequency modulation. Based on these results, the power-broadening characteristics were measured. Finally, the relation between the dip width free from the power broadening and the pressure of H2CO was obtained. The dip width (HWHM) was Δνh= (123±24)+(155±31) PF (kHz), where PF represents the H2CO pressure expressed in Pascal.