gebhart/patrepeval huggingface dataset:
Evaluation of Cateto Maize Accessions for Grain Yield and Physical Grain Quality Traits (1994)

Because many exotic corn ( Zea mays L.) races have different evolutionary histories from those of U.S. races, they may possess unique, favorable alleles for physical grain quality traits. This study explored the effectiveness of using exotic inbreds from Uruguay, Argentina, South Africa, and Taiwan (representing ‘Cateto’‐type, intermediate, and non‐Cateto races) to improve physical grain quality of U.S. Corn Belt hybrids. Eighteen exotic inbreds were crossed to two Corn Belt inbreds, Mo17 and B73, which represent the ‘Lancaster Sure Crop’ and the ‘Iowa Stiff Stalk Synthetic’ backgrounds, respectively. A randomized complete block design was used to evaluate testcrosses (F 1 s), their F 2 and backcross (to the Corn Belt inbreds) generations, and four checks grown at two locations in Iowa and at one location in Missouri. The experiment showed significant differences among races for 1000‐kernel weight, test weight, grain yield, and harvest moisture content. Testcrosses and generations were significantly different for kernel weight, test weight, breakage susceptibility, grain yield, and harvest moisture content. Significant differences were also found between testers for all traits except moisture. Entry × tester interaction, however, was significant only for breakage susceptibility and yield, whereas entry × generation interaction was significant for all the traits except breakage susceptibility. This study showed that Catetotype inbreds have the potential to improve test weight of Corn Belt hybrids. The Cateto race inbreds also contributed favorable alleles for lowering harvest moisture content, which may indirectly help reduce breakage losses.
Drugs used in ovulation induction. Safety of patient and offspring* (1986)

Data on the safety of agents used to induce ovulation in women are presented, with a special reference to the normality of children at birth and puberty. No overall increase in anomalies has been found after the use of clomiphene citrate. This drug has been given up to day 35 of pregnancy, and its safety in these circumstances requires further analysis. More studies will also be needed on offspring as they pass through puberty, to ensure there are no defects in their Müllerian system. No increase in anomalies has been noted after the use of human menopausal gonadotrophins (HMG). The onset of menstrual rhythms and other parameters in the offspring appear to be normal. No increase in various cancers has been identified following the use of clomiphene or HMG, although most treated women have yet to enter the high risk years.
A mutation causing DHPR deficiency results in a frameshift and a secondary splicing defect. (1995)

In our analysis of mutations causing DHPR deficiency we identified a patient in whom there was an aberrant transcription pattern detected by PCR of DHPR cDNA. However, unlike the pattern observed as a result of most splicing mutations, there is some full length transcript. The mutation was located and is a single nucleotide deletion at position 570/571 of the DHPR cDNA sequence and results in a frameshift and premature termination after the addition of six amino acids. The mutation is present in a homozygous state in the patient and in a heterozygous state in both parents. The exon which is deleted at high frequency in the patient is the putative exon 4, which is remote from the mutation, and confirms our observation that exon 4 skipping is a relatively common event.
Investigation of the In-Cylinder Tumble Motion In a Multi-Valve Engine: Effect of the Piston Shape (1997)

<div class="htmlview paragraph">An experimental investigation is carried out on in-cylinder motion, during the intake and compression strokes of a spark-ignited multi-valve engine. This study is conducted on a single cylinder four valve research engine. The engine is equipped with several optical accesses on cylinder liner and cylinder head. The turbulence and local velocity in combustion chamber were measured by Laser Doppler Velocimetry. Furthermore, effects of different bowl shapes on turbulence, cycle by cycle flow variations, and tumble distortion were studied.</div> <div class="htmlview paragraph">Tumble velocity field exhibits a triplet vortices structure composed of one vertical and two horizontal vortices. This structure is induced during the inlet stroke, and remains during compression. In the latest stage of compression, tumble is converted into a pair of horizontal vortices. Velocity measurements in the cylinder show a precession motion of tumble center. Distortion of tumble is very unstable and perturbed with a flat top piston. Cycle by cycle variations of tumble timing distortion is observed, increasing velocity fluctuations. A new approach to remove cycle by cycle variations at the end of the compression stroke, when computing cycle-resolved turbulence, is proposed.</div> <div class="htmlview paragraph">Bowls reduce cycle by cycle flow variations and turbulence intensity at ignition. Furthermore, steady flow rig measurements, as LDV investigations on the single cylinder during the intake stroke, demonstrate the influences of the bowl location on the tumble charge angular momentum at the end of the intake stroke.</div>
P<sub>2</sub>‐Purinergic Receptors on Vascular Endothelial Cells (1990)

SCOPUS: cp.j
The power of dispersion management for 10-Gb/s and 40-Gb/s systems (2006)

We review applications and requirements of dispersion compensation that enable high-capacity, long-haul, and ultra-long-haul 10-Gb/s and 40-Gb/s DWDM transmission. We briefly describe their impact on system performance and present some future perspectives.
Relative effectiveness of natural and synthetic biocides against bacteria found in sugar factories (2005)

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The COST 2100 MIMO channel model (2012)

The COST 2100 channel model is a geometry- based stochastic channel model (GSCM) that can reproduce the stochastic properties of MIMO channels over time, frequency, and space. In contrast to other popular GSCMs, the COST 2100 approach is generic and flexible, making it suitable to model multi-user or distributed MIMO scenarios. In this article a concise overview of the COST 2100 channel model is presented. Main concepts are described, together with useful implementation guidelines. Recent developments, including dense multipath components, polarization, and multi-link aspects, are also discussed.
Enhanced Optical Forces in Hybrid Plasmonic Devices (2012)

We demonstrate that the optical force exerted on a suspended dielectric waveguide coupled to a metallic substrate is greatly enhanced compared to dielectric substrate, due to subwavelength optical energy confinement in the hybrid plasmonic mode.
Book reviews (1989)

The Beginning and the End by Naguib Mahfouz, translated by Ramses Hanna Awad and edited by Mason Rossiter Smith. Cairo: American University in Cairo Press, 1985. Pp.379. $7.95. The Search by Naguib Mahfouz, translated by Mohamed Islam and edited by Magdi Wahba. Cairo: American University in Cairo Press, 1987. Pp.126. $8.95. The Beggar by Naguib Mahfouz, translated by Kristin Walker Henry and Nariman Khales Naili al‐Warraki. Cairo: American University in Cairo Press, 1986. Pp. 124. $7.95. Banking and Oil: The History of the British Bank of the Middle East by Geoffrey Jones. Volume 2, Cambridge University Press, 1987. Pp.380. £40. Syria and the French Mandate: The Politics of Arab Nationalism, 1920–1945 by Philip Khoury. London: I.B. Tauris and Co. 1987. Pp.698. £37.50. Nomads and Settlers in Syria and Jordan 1800–1980 by Norman N. Lewis. Cambridge: Cambridge University Press, 1987. Futile Diplomacy, volume two: Arab‐Zionist negotiations and the End of the Mandate by Neil Caplan. London: Frank Cass, 1986. Pp.358, including documents, bibliography and index. £27.50. The Dynamics of Inflation in Iran: 1960–1977 by Azizollah Ikani. The Netherlands: Tilburg University Press, 1987. DFL 42.40.
Abstract 902: Cancer-stem-cell (CSC) marker, DCLK1-S, enhances invasive potential of cancer cells by phosphorylating/activating NFATc2: role of COL3A1 and SPARC in mediating metastatic effects of DCLK1-S/NFATc2 (2017)

Abstract DCLK1 expression is critically required for colon carcinogenesis in mice, and for maintaining tumorogenic potential of human colon cancer cells (hCCCs) (Singh et al, 2016). Down-regulation of DCLK1, combined with chemoprevention, eliminates CSCs, and avoids colon cancer relapse (Kantara et al, 2014). We recently discovered that long (L) and Short (S) isoforms of DCLK1 (DCLK1-L/DCLK1-S) are transcribed by two separate promoters (5’(α)/IntronV(β)) in the hDCLK1-gene (O’Connell et al, 2015). During adenoma-carcinoma sequence of colon-tumorigeneses, L-isoform becomes silenced by DNA-methylation while S-isoform gets upregulated by many fold (O’Connell et al, 2015). S-isoform specifically imparts invasive potential to cancer cells, unlike L-isoform (Singh et al, 2016); others have similarly reported metastatic potential of DCLK1 expressing cancer cells (Ito et al, 2016). Thus the goal of our studies was to evaluate molecular/genetic pathways mediating invasive effects of DCLK1-S in cancer cells. Isogenic clones of HCT116-cells, wild-type or down-regulated for DCLK1-S (HCT-C/HCT-D), were subjected to next generation sequencing and pathways analysis. SPARC and COL3A1 emerged as two candidate genes/proteins, which were decreased/increased by several fold in response to loss/overexpression of DCLK1-S, respectively. We present data confirming a critical role of COL3A1 and SPARC in mediating metastatic effects of DCLK1-S expression in hCCCs. We additionally discovered that DCLK1-S functions as a specific kinase for the transcriptional factor, NFATc2, and phosphorylates 53SPPS56 motif of NFATc2, resulting in activation of NFATc2 and increased expression of COL3A1. Conclusions. Our novel findings, suggest for the first time, that DCLK1-S expression by colonic tumors in humans, mediates invasive potential of colon cancer cells by phosphorylation/activation of NFATc2, resulting in up-regulation of COL3A1/SPARC; the latter proteins re-model extracellular matrix, assisting unhindered invasion of colon cancer cells. Note: This abstract was not presented at the meeting. Citation Format: Malaney O. Connell, Shubhashish Sarkar, Heidi Spratt, Steven Widen, Thomas G. Wood, Pomila Singh. Cancer-stem-cell (CSC) marker, DCLK1-S, enhances invasive potential of cancer cells by phosphorylating/activating NFATc2: role of COL3A1 and SPARC in mediating metastatic effects of DCLK1-S/NFATc2 [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2017; 2017 Apr 1-5; Washington, DC. Philadelphia (PA): AACR; Cancer Res 2017;77(13 Suppl):Abstract nr 902. doi:10.1158/1538-7445.AM2017-902
Über die Kantenemission und andere Emissionen des GaN (1959)

Es werden die Fluoreszenzeigenschaften des reinen und des mit Lithium, Zink und Magnesium dotierten GaN bei Anregung mit UV-Licht und Kathodenstrahlen in Abhängigkeit der Temperatur untersucht. Mehrere Emissionsbanden wurden beobachtet, von denen die kurzwelligste Bande als Rckombinationsstrahlung freier Elektronen mit freien Löchern gedeutet wird.
330. The disappearance of carbon monoxide in the presence of electrically heated nickel filaments (1936)

G. Bryce, J. Chem. Soc., 1936, 1513 DOI: 10.1039/JR9360001513
OC-034 Identifying Patients with Elevated Circulating Bacterial DNA May Reduce Infection and Death in Alcoholic Hepatitis (2016)

<h3>Introduction</h3> Prednisolone has been shown to improve 28 day survival in alcoholic hepatitis (AH). However, use of this therapy is associated with increased infection that could explain the loss of survival benefit by 90 days. A large body of data has also emerged implicating bacterial translocation in the pathogenesis of AH. We therefore sought to elucidate the impact of prednisolone in patients with elevated pre-treatment circulating bacterial DNA (bDNA). <h3>Methods</h3> DNA was extracted from the whole blood of patients recruited to the STOPAH study before therapy. In these patients, clinicians confirmed that any prior infection, if present, was controlled. bDNA levels were quantified by quantitative PCR using a Taqman probe that targeted a region within a 380 bp fragment of bacterial 16 S ribosomal DNA. As part of the STOPAH study, patients would then receive therapy with or without prednisolone by random allocation. After unmasking, levels of bacterial DNA were then compared to clinical outcomes such as the development of infection within 7 days, static and dynamic markers of liver function and mortality at 28 and 90 days. <h3>Results</h3> bDNA was quantified in 714 whole blood samples. There was no correlation between bDNA levels and baseline characteristics such as age and gender, nor with static markers of liver function such as MELD. Elevated bDNA levels were associated with development of infection within the first 7 days in patients treated with prednisolone (<i>p</i> = 0.001), and remained independently associated with the subsequent development of infection after multivariate analysis (<i>p</i> = 0.02). Importantly, bDNA levels were not associated with the development of infection in patients treated without prednisolone (<i>p</i> = 0.43). Elevated bDNA levels were associated with death at 90 days (<i>p</i> = 0.05). Mortality in prednisolone treated patients was increased for patients with high bDNA compared to patients with low bDNA (hazard ratio 2; <i>p</i> = 0.02). Accordingly, patients with elevated bDNA were more likely to die if they were randomly allocated prednisolone therapy (OR 2.9, 95% CI 1.2–6.9, <i>p</i> = 0.02). We estimate that if patients with elevated bDNA were instead treated without prednisolone, 90 day mortality in AH could be reduced (odds ratio 0.5, <i>p</i> = 0.03 [one-tailed]). <h3>Conclusion</h3> Infection is more likely to develop within 7 days if patients with elevated bDNA are treated with prednisolone. Measuring pre-treatment bDNA could therefore inform decisions to initiate corticosteroid therapy and has the potential to increase survival at 90 days in AH. <h3>Disclosure of Interest</h3> None Declared
Insertion Reactions into Palladium–Carbon Bonds of Complexes Containing Terdentate Nitrogen Ligands; Experimental and Ab initio MO Studies (1998)

Novel methyl complexes [Pd(Me)(N-N-N)]X (N-N-N = flexible or rigid terdentate nitrogen ligand, X = Cl, SO3CF3, BAr′4) have been synthesized and fully characterized. All complexes readily underwent insertion of carbon monoxide resulting in the quantitative formation of complexes [Pd{C(O)Me}(N-N-N)]X [X = Cl (1d–6d), BAr′4 (1e–6e)]. Subsequently, complexes 2e–6e underwent quantitative insertion of norbornadiene, resulting in complexes [Pd{C7H8C(O)Me}(N-N-N)]BAr′4 (2f–6f). Unexpectedly, these complexes, including even those containing rigid terdentate nitrogen ligands, possess a structure in which the nitrogen ligand is coordinated in a bidentate fashion. A kinetic study of the reaction of norbornadiene with complexes 1e–6e revealed that the reactivity of complexes 1e–6e toward norbornadiene increases with increasing rigidity of the terdentate ligand, i.e. with increasing strain in the PdN3 moiety, which indicates that insertion very likely occurs via a mechanism involving nitrogen dissociation. This is fully supported by ab initio MO calculations on CO and ethylene insertion into carbon–palladium bonds of cationic model systems containing a rigid terdentate nitrogen ligand, which showed that the lowest-energy pathway for both insertion reactions consists of substitution of one of the distal nitrogen atoms of the rigid terdentate nitrogen ligand by the substrate, followed by a rate-determining migratory insertion of the substrate into the carbon–palladium bond.
Fluorescence-line narrowing in CdSe quantum dots: Surface localization of the photogenerated exciton (1994)

The electronic properties of shallow band-edge surface traps in nanometer-size CdSe quantum dots are probed using fluorescence-line-narrowing spectroscopy. We find large changes in electron-hole-pair radiative lifetimes and couplings to LO phonons as the temperature is changed from 1.75 to 10 K. We attribute these changes to the localization of the photogenerated hole at the surface of the dots, accompanied by thermally activated motion between these surface localized states. A simple model based on the observed exciton--LO-phonon couplings is constructed to estimate the extent of hole localization in the luminescing state. A size-dependent study (20--80 \AA{} diameter) indicates that surface effects diminish rapidly with increasing size.
Carcinoembryonic antigen: immunohistologic identification in invasive and intraepithelial carcinomas of the lung. (1977)

A total of 58 pulmonary lesions from 48 patients were examined for carcinoembryonic antigen (CEA). The three-layer immunoperoxidase procedure for antigen detection was used with a monospecific anti-CEA antiserum. The control serum was the same antiserum with its specificity removed by affinity chromatography. Normal goat serum was also used as a control. Carcinoembryonic antigen was present in the majority of pulmonary adenocarcinomas and generally absent in the squamous cancers. The major exception was in the well-differentiated squamous lesions where CEA was occasionally found in the keratinizing areas. Of special interest was the finding of CEA in all areas of intraepithelial squamous neoplasia studied.
The transmembrane tyrosine of  -heavy chain is required for BCR destabilization and entry of antigen into clathrin-coated vesicles (2007)

The B cell antigen receptor (BCR) delivers antigen to the endocytic compartment and transduces signals that regulate the stability of the receptor complex. Previous studies showed that BCR-mediated signal transduction dissociates micro-heavy chain (microm) from Ig-alpha/Ig-beta, facilitating the delivery of antigen to clathrin-coated vesicles (CCVs). Herein, we demonstrate that the dissociation of Ig-alpha/Ig-beta from microm requires tyrosine-587 of the microm transmembrane domain. Receptors expressing a mutation at tyrosine-587 (Y587F) transduced signals that were comparable to wild type, yet they failed to dissociate microm from Ig-alpha/Ig-beta. Further, receptors harboring the Y587F mutation failed to associate with CCVs, resulting in diminished antigen in the lysosome-associated membrane protein-1 (LAMP-1(+)) compartment and severely impaired antigen presentation, indicating that endocytosis through CCVs is required for antigen presentation. Thus, the transmembrane tyrosine of mum mediates destabilization of the BCR complex, facilitating antigen processing by promoting the association of antigen with CCVs.
In vivo sampling and biochemistry of tracheobronchial secretions in the fowl. Influence of sulfurdioxide inhalation. (1981)

A new method for collecting tracheobronchial secretions from the anesthesized fowl has been developed. Sulfurdioxide inhalation leads to a highly significant increase of mucus output (wet weight), 320 % of control. Glycoprotein output is increased by only 50 %. Thus glycoprotein concentration is lowered to about 1/3 that of the control group. The carbohydrate pattern of the glycoproteins shows no significant alteration after sulfurdioxide treatment. Isoelectric focusing of te glycoprotein subunits derived from papain digestion shows no difference between the macromolecular pattern of the control and SO2 group.
Transport of the aromatic amino acids into isolated rat liver cells by a ‘T’ system (1985)

Conference Article| August 01 1985 Transport of the aromatic amino acids into isolated rat liver cells by a ‘T’ system MARK SALTER; MARK SALTER 1Department of Biochemistry, University of Manchester, Oxford Road, Manchester M13 9PL, U.K. Search for other works by this author on: This Site PubMed Google Scholar RICHARD G. KNOWLES; RICHARD G. KNOWLES 1Department of Biochemistry, University of Manchester, Oxford Road, Manchester M13 9PL, U.K. Search for other works by this author on: This Site PubMed Google Scholar CHRISTOPHER I. POGSON CHRISTOPHER I. POGSON * 1Department of Biochemistry, University of Manchester, Oxford Road, Manchester M13 9PL, U.K. Search for other works by this author on: This Site PubMed Google Scholar Biochem Soc Trans (1985) 13 (4): 693–694. https://doi.org/10.1042/bst0130693a Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter LinkedIn Cite Icon Cite Get Permissions Citation MARK SALTER, RICHARD G. KNOWLES, CHRISTOPHER I. POGSON; Transport of the aromatic amino acids into isolated rat liver cells by a ‘T’ system. Biochem Soc Trans 1 August 1985; 13 (4): 693–694. doi: https://doi.org/10.1042/bst0130693a Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsBiochemical Society Transactions Search Advanced Search Keywords: BCH, 2-aminobicyclo-)2,2,1)-heptane-2-carboxylic acid, MAIB, N-methyl-2-amino-2-methylpropanoate This content is only available as a PDF. © 1985 Biochemical Society1985 Article PDF first page preview Close Modal You do not currently have access to this content.
Context Change Archetypes: Understanding the Impact of Context Change on Business Processes (2009)

The emergence of Enterprise Resource Planning systems and Business Process Management have led to improvements in the design, implementation, and overall management of business processes. However, the typical focus of these initiatives has been on internal business operations, assuming a defined and stable context in which the processes are designed to operate. Yet, a lack of context-awareness for external change leads to processes and supporting information systems that are unable to react appropriately and timely enough to change. To increase the alignment of processes with environmental change, we propose a conceptual framework that facilitates the identification of context change. Based on a secondary data analysis of published case studies about process adaptation, we exemplify the framework and identify four general archetypes of context-awareness. The framework, in combination with the learning from the case analysis, provides a first understanding of what, where, how, and when processes are subjected to change.
Self-Assembled Phenylethynylene Bis-urea Macrocycles Facilitate the Selective Photodimerization of Coumarin (2011)

There is much interest in designing molecular sized containers that influence and facilitate chemical reactions within their nanocavities. On top of the advantages of improved yield and selectivity, the studies of reactions in confinement also give important clues that extend our basic understanding of chemical processes. We report here, the synthesis and self-assembly of an expanded bis-urea macrocycle to give crystals with columnar channels. Constructed from two C-shaped phenylethynylene units and two urea groups, the macrocycle affords a large pore with a diameter of ∼9 Å. Despite its increased size, the macrocycles assemble into columns with high fidelity to afford porous crystals. The porosity and accessibility of these channels have been demonstrated by gas adsorption studies and by the uptake of coumarin to afford solid inclusion complexes. Upon UV-irradiation, these inclusion complexes facilitate the conversion of coumarin to its anti-head-to-head (HH) photodimer with high selectivity. This is contrary to what is observed upon the solid-state irradiation of coumarin, which affords photodimers with low selectivity and conversion.