gebhart/patrepeval huggingface dataset:
Construcción y apertura de teatros madrileños en el siglo XIX (1974)

Las escasas monografias dedicadas a los teatros madrilenos dd sigjo xix ampilaciones de anecdotas en su mayor parte, aportan pocos datos concretos sobre la historia y las caracteristicas de los edificios e instalaciones. Sin embargo, existe material suficiente para conocer tales aspectos. El Archivo de Villa, en la Seccion Secretaria, Subseccion Teatros Particulares, conserva una serie de expedientes con documentos y planos de gran interes. El Historico Nacional, entre los papeles de Consejos, bajo la denominacion de Diversiones Publicas, posee otro conjunto estimable. Ambos fondos, mas los principales diarios de la epoca 'que se ocupan can preferencia de los proyectos, estado de la construccion y, por fin, del acto inaugural de cada coliseo, nos han permitido reconstruir la historia de la edificacion y apertura de buen numero de teatros madrilenos del siglo XIX, parte de los cuales continuan funcionando en nuestros dias.
A rapid synthesis of A‐ring bromine‐77‐labelled estrogens with high specific activity (1981)

Abstract A rapid method of no‐carrier‐added radiobrominations of A‐ring estrogens has been demonstrated. The method employs N‐chlorosuccinimide and high specific activity sodium bromide‐77 to generate an electrophilic brominating agent, which when reacted with phenolic steroids, yields three primary products. Two of the radiobrominated products have been shown to be the phenolic ortho brominated regioisomers, and the third product is believed to be a reaction intermediate. The use of HPLC afforded a method of separation and isolation of radiobrominated products. The 2‐bromo‐ 77 Br‐ and 4‐bromo‐ 77 Br‐ isomers were found to be quite stable in vitro , where‐as the suspected intermediates were not. A specific activity range of 600‐1200 Ci/mmole and radiochemical yields of 25‐30% were obtained for the 4‐bromo‐ 77 Br regioisomers.
3,5-Bis[(<i>N</i>,<i>N</i>-dimethylamino)methyleneamino]-1-methyl-4-nitropyrazole from X-ray powder diffraction data (2000)

The structure of the title compound, C(10)H(17)N(7)O(2), was determined using a bond-restrained Rietveld refinement which gave bond lengths and angles within the expected ranges. Although the two nearly planar (N,N-dimethylamino)methyleneamino groups are inclined at approximately 46 degrees to the pyrazole ring, the conformations of the two amino chains are different, owing to either a repulsion effect of the pyrazole-methyl group or a short interatomic contact with the nitro group in one of the chains.
Magnesium Alloys and Their Structural Application (1937)

The combination of light weight with the improved mechanical properties of the newer magnesium alloys makes these materials of increasing interest to the civil engineer. Since 1933 or 1934, production costs have been reduced, and properties have improved to the point where the alloys are finding many successful applications formerly considered impractical for the material. In this period a number of important applications have developed in the transportation field. As might be expected, because of the necessity for light weight, the airplane industry was the first to adopt these alloys in all types of service. Sand castings of magnesium alloys are used universally in airplane motor and starter castings, in landing wheels and brakes, and as brackets and fittings in the airplane structure.
The use of reactant‐fixable dyes in the dyeing of cellulosic blends (1988)

The use of Indosol reactant‐fixable dyes in the dyeing of cellulosic blends is described. Detailed descriptions of the various fixation methods are given. The possible problems in blend dyeing with Indosol systems and the solutions to those problems are discussed. The advantages of Indosol systems in terms of time and cost savings are described.
A Traffic Model for Velocity Data Assimilation (2010)

This article is motivated by the practical problem of highway traffic estimation using velocity measurements from GPS enabled mobile devices such as cell phones. In order to simplify the estimation procedure, a velocity model for highway traffic is constructed, which results in a dynamical system in which the observation operator is linear. This article presents a new scalar hyperbolic partial differential equation (PDE) model for traffic velocity evolution on highways, based on the seminal Lighthill-Whitham-Richards (LWR) PDE for density. Equivalence of the solution of the new velocity PDE and the solution of the LWR PDE is shown for quadratic flux functions. Because this equivalence does not hold for general flux functions, a discretized model of velocity evolution based on the Godunov scheme applied to the LWR PDE is proposed. Using an explicit instantiation of the weak boundary conditions of the PDE, the discrete velocity evolution model is generalized to a network, thus making the model applicable to arbitrary highway networks. The resulting velocity model is a nonlinear and nondifferentiable discrete time dynamical system with a linear observation operator, for which a Monte Carlo based ensemble Kalman filtering data assimilation algorithm is applied. The model and estimation technique is evaluated with experimental data obtained from a large-scale field experiment known as Mobile Century, which is available for download at http://traffic.berkeley.edu.
Management of trapped microwire during femoral arterial access in a pediatric patient (2014)

Femoral arterial access complications (e.g., arteriovenous fistula, pseudoaneurysm, vessel dissection, haematoma and vasospasm) are not uncommon and are likely underreported in the pediatric population. We present a case of severe vasospasm with microwire entrapment during attempted femoral arterial access in a 20-month-old. Successful microwire removal was achieved after systemic administration of nitroglycerin using a combination of pharmacological techniques that benefited from close collaboration between the interventional neuroradiology, pediatric interventional cardiology and anaesthesia teams.
Optimization of Si/sub 1-x/Ge/sub x//Si waveguide photodetectors operating at λ=1.3 μm (1996)

This paper analyzes the influence of various design parameters in the external quantum efficiency (QE) of waveguide detectors based on Si/Si/sub 1-x/Ge/sub x/ strained-layer superlattices (SLSs), for use in optical communications at /spl lambda/=1.3 /spl mu/m. The study presents an algorithm that automatically generates structurally stable SLSs. This generation is completed by intensive simulation of the generated SLSs to calculate the external QE. The simulation embraces optical waveguiding, absorption, quantum size effect, as well as thermodynamics of the strained layers. Two sets of data were created using two different models for the SiGe layer critical thickness, h/sub c/(x). A conservative model for h/sub c/, corresponding to the equilibrium regime, yielded discrete maximum values for QE (around 12%) that were mainly dependent on the alloy absorption. A second model for h/sub c/, corresponding to the metastable regime, produced considerably higher QEs (around 60%), and shows the great importance of fiber-to-waveguide coupling efficiency. The importance of the passive-waveguide coupler geometry is investigated using the beam propagation method.
Surface properties of mesoporous silicate and alumino-silicate modified by reaction with benzoyl chloride (2002)

The preparation of mesoporous silicate and alumino-silicate by different synthesis methods are reported together with their surface modification. Specific surface area of starting samples ranges between 400 and 1100 m2/g. Benzoyl chloride was used to graft the benzoyl group to the surface. FT-IR spectra of modified samples show a peak centred at 1705 cm−1 assigned to the stretching vibration of carbonyl group of benzoic ester. The 13C NMR spectra also clearly show the benzoyl groups attached at the surface. Modified samples show lower specific surface areas and pore volume with respect to the corresponding values for starting materials. The weight ratio between benzoyl and silica was also calculated by thermogravimetrical analysis. Mesoporous materials and their reactivity open new perspectives in the possibility of designing catalysts.
Mobile Data Network Analysis Platform (2015)

In this paper we present a platform installed inside a French mobile operator's network. This platform is able to capture around 20Gb/s per network probe in the operator's Points Of Presence (POPs), capable of extracting useful information at wire speed, and storing it for offline analysis. We detail how efficient network probes can be built using off-the-shelf hardware and software. We describe preliminary experiments which demonstrate that our system can easily extract and process the signaling traffic generated by the connections of a large number of mobile devices (on the order of 50 million signaling messages per hour). This platform is designed to exploit the user traffic as well as the signaling flows and thus to produce performance indicators of Quality of Service (QoS), detecting suspicious traffic or even studying mobility. Moreover, since mobile operators are gradually switching their networks toward full IP, the data mobile network will become the place where everything transits, voice and data.
Chorioamnionitis-induced fetal gut injury is mediated by direct gut exposure of inflammatory mediators or by lung inflammation (2014)

Intra-amniotic exposure to proinflammatory agonists causes chorioamnionitis and fetal gut inflammation. Fetal gut inflammation is associated with mucosal injury and impaired gut development. We tested whether this detrimental inflammatory response of the fetal gut results from a direct local (gut derived) or an indirect inflammatory response mediated by the chorioamnion/skin or lung, since these organs are also in direct contact with the amniotic fluid. The gastrointestinal tract was isolated from the respiratory tract and the amnion/skin epithelia by fetal surgery in time-mated ewes. Lipopolysaccharide (LPS) or saline (controls) was selectively infused in the gastrointestinal tract, trachea, or amniotic compartment at 2 or 6 days before preterm delivery at 124 days gestation (term 150 days). Gastrointestinal and intratracheal LPS exposure caused distinct inflammatory responses in the fetal gut. Inflammatory responses could be distinguished by the influx of leukocytes (MPO(+), CD3(+), and FoxP3(+) cells), tumor necrosis factor-α, and interferon-γ expression and differential upregulation of mRNA levels for Toll-like receptor 1, 2, 4, and 6. Fetal gut inflammation after direct intestinal LPS exposure resulted in severe loss of the tight junctional protein zonula occludens protein 1 (ZO-1) and increased mitosis of intestinal epithelial cells. Inflammation of the fetal gut after selective LPS instillation in the lungs caused only mild disruption of ZO-1, loss in epithelial cell integrity, and impaired epithelial differentiation. LPS exposure of the amnion/skin epithelia did not result in gut inflammation or morphological, structural, and functional changes. Our results indicate that the detrimental consequences of chorioamnionitis on fetal gut development are the combined result of local gut and lung-mediated inflammatory responses.
Ueber Trypanosomentoxine und trypanotoxische Keratitis parenchymatosa (1908)

Drug Prescribing for Patients with Chronic Kidney Disease in General Practice: a Cross-Sectional Study
An Electrohydraulic Ventricular Assist System with a Linear Actuator (1989)

An electrohydraulic ventricular assist system with a linear actuator was developed, and in vitro and in vivo evaluations were performed. During in vitro evaluations this system could yield 5.6 L/min of pump flow against a mean after-load of 100 mmHg. Durability tests were performed for more than 4 months. The system was implanted in three goats and a maximum pump flow of 4.2 L/min was obtained against a mean afterload of 100 mmHg, and 3.2 L/min against 130 mmHg. These evaluations have proven that the system can maintain stable hemodynamics under various conditions.
High-performance hole-transporting layer-free conventional perovskite/fullerene heterojunction thin-film solar cells (2015)

MAPbI<sub>3</sub> perovskite was found to be able to modify the work function of ITO, leading to sufficient charge extraction efficiency at the ITO/perovskite interface. A device with a high power conversion efficiency of >11% was obtained.
Pourquoi la Francophonie ? (2012)

Essayons d’envisager la question d’une maniere moins etroite en evoquant d’abord le rapport de la langue avec la culture ; une fois reconnu ce rapport fusionnel, il faut bien trouver une reponse a l’argument apparemment imparable : pourquoi pas une langue et une culture universelles, idee qu’ont caressee de grands penseurs, des linguistes ou des dirigeants politiques bien sur ! Et nous evoquerons les tentatives d’uniformisation, leur echec inevitable, et la renaissance permanente, la proliferation grouillante, bourgeonnante, de « rejets » de la langue, de diversification, de rameaux evolutifs completement incontrolables, de marcottes prolixes, de greffons exuberants... E D I T O R I A L
The role of synthetic biology in climate change mitigation (2019)

There is growing agreement that the aim of United Nations Framework Convention on Climate Change, which is to avoid dangerous anthropogenic interference with the climate system, is not likely to be met without inclusion of methods to physically remove atmospheric carbon. A number of approaches have been suggested, but the community appears to be silent on the potential of one of the most revolutionary technologies of the current century, systems and synthetic biology (SSB). The potential of SSB to modulate the fast carbon cycle, and thereby mitigate climate change is in itself enormous, but if the history of genomics is any measure, it is also reasonable to expect sizeable economic returns on any investment. More generally, the approach to climate control has been badly unbalanced. The last three decades have seen intense international attention to emission control, with no parallel plan to test, scale and implement carbon removal technologies, including attention to their economic, legal and ethical implications. REVIEWERS: This article was reviewed by Richard Roberts, Aristides Patrinos, and Eugene Koonin, all of whom were nominated by Itai Yanai. For the full reviews, please go to the Reviewers' comments section.
Bacillus subtilis GlcK activity requires cysteines within a motif that discriminates microbial glucokinases into two lineages (2004)

Our results emphasize the necessity of cysteines within the CXCGX(2)GCXE motif for GlcK activity. On the other hand, the C321A mutation led to higher GlcKC321A enzymatic activity with respect to the wild type's, suggesting more adequate glucose phosphorylation.
Fabrication of Integrated Two-Axis High-$T_{\rm c}$ Planar Gradiometer (2011)

We have fabricated a two-axis high-T <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">c</sub> planar gradiometer. Two gradiometers with planar gradiometric pickup coils lie diagonally on a square substrate. Therefore, they can measure field gradients, dBz/dx and dBz/dy at the same site. The two-axis gradiometer was fabricated on a 15 × 15 mm MgO (100) substrate using an HTS multilayer process including crossovers, superconductive contacts and ramp-edge junctions. The width of the pickup coil and the baseline length are 6 mm and 8.5 mm, respectively. Voltage modulations in V-Φ characteristics more than 20 μV at 77 K were obtained for both the gradiometers. Parasitic effective areas measured by applying a uniform magnetic field were about 0.0001 mm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">-2</sup> . The gradiometer balance was estimated to be about 10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">-2</sup> . The parasitic effective area was not due to the imbalance of the gradiometric pickup coil, but due to a sensitivity of SQUID itself. Flux noise level as low as 10 μΦ <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">0</sub> /Hz <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">1/2</sup> at frequencies down to 3 Hz and a cross-talk ratio less than 1/230 were obtained.
Molecular markers of prognosis in astrocytic tumors (2002)

The results suggest that LOH on 9p and p16 deletions may prove to be objective standards for the diagnosis of patients with high-grade gliomas, although the absence of these abnormalities is nonprognostic.
Abstract 2924: Evaluation of the pan-FGFR inhibitor AZD4547 with radiation in non-small cell lung cancer (2019)

Objective: The fibroblast growth factor receptors (FGFR) are commonly altered in non-small cell lung cancer (NSCLC), including high level of amplification of FGFR1 in lung squamous cell carcinoma. FGFR signaling may play a role in the response to radiation. We investigated the radiosensitizing effects of the selective tyrosine kinase inhibitor AZD4547 in a NSCLC model using cell lines and tumor xenografts.Methods: A panel of six NSCLC cell lines were screened for FGFR1/2 DNA amplification, RNA expression, and protein expression. All cells were assessed for in vitro response to AZD4547. Immunoblots were used to examine the effect of AZD4547 on downstream signaling proteins. Apoptosis was measured by Annexin V staining and autophagy with acridine orange assay. Radiation clonogenic survival assays and xenograft growth delays experiments were performed to investigate radiosensitization. In vivo mechanistic studies were conducted using immunohistochemistry.Results: Cell lines demonstrated varying degree of FGFR1/2 RNA and protein expression. In sensitive cell lines, AZD4547 inhibited p-MAPK in a time dependent manner. In vitro clonogenic survival assays showed robust radiosensitivity with AZD4547 in three out of six NSCLC cell lines. All three cell lines overexpressed FGFR1 and two of the cells had high FGFR1 copy number. There was no radiosensitization seen in an immortalized normal human bronchial epithelial cell line. A significant increase in autophagy and apoptosis was observed with combined radiation and AZD4547. Significant tumor growth delay was observed with the administration of radiation and AZD4547 compared to radiation or drug alone in two NSCLC xenograft tumor models. IHC analysis revealed modulation of FGFR-downstream signaling (p-Erk and p-S6) and proliferative (Ki67) and apoptotic markers (Cleaved Caspace 3).Conclusion: These findings suggest that AZD4547 can augment the response of radiation in NSCLC model systems. FGFR1 and FGFR2 expression may be a potential targets for radiosensitization in NSCLC. Additional studies are underway to understand the mechanism of radiosensitization.Citation Format: Margot Miller, Michael Fisher, Gopika Senthilkumar, Saakshi Kaushik, Lindsey Able, Sean Brennan, Gopal Iyer, Randall Kimple, Andrew M. Baschnagel. Evaluation of the pan-FGFR inhibitor AZD4547 with radiation in non-small cell lung cancer [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2019; 2019 Mar 29-Apr 3; Atlanta, GA. Philadelphia (PA): AACR; Cancer Res 2019;79(13 Suppl):Abstract nr 2924.
Transporting Stratospheric Water Vapor in the GMI Combo Model (2007)

I discuss the implementation of an H2O transport scheme in the Global Modeling Initiative (GMI) model.
One-Dimensional photonic crystal with superconducting defect layer: Oblique incidence of the light (2010)

The influence of the incidence angle on the photonic band gap spectra of the one-dimensional dielectric photonic crystal with a complex defect layer, consisting of ultrathin superconducting and dielectric sublayers is theoretically investigated. It is shown that the positions of the defect mode and the photonic band gaps as well as the transmittivity spectra strongly depend on the incidence angle and a thickness of superconducting sublayer.
Selective Down-Regulation by Protein Kinase C Inhibitors of Apolipoprotein-Mediated Cellular Cholesterol Efflux in Macrophages (1997)

Extracellular apolipoprotein A-I removed cholesterol and phospholipid from cholesterol-loaded mouse peritoneal macrophage and thereby generated a prebeta high-density lipoprotein (HDL) particle having a weight ratio of cholesterol to phosphatidylcholine of approximately 1:1. Treatment of the cells with phorbol myristate slightly increased cholesterol efflux by this mechanism without influencing the nonspecific cholesterol efflux to the lipid microemulsion. When the cells were treated by protein kinase C (PKC) inhibitors, H7 and staurosporine, apolipoprotein-mediated cellular cholesterol efflux was substantially reduced without a significant change in phosphatidylcholine efflux, resulting in generation of cholesterol-poor prebeta-HDL particles having a weight ratio of cholesterol to phosphatidylcholine as low as 1:10. In spite of this change, specific binding of apoA-I to the cellular surface was unaffected. Cellular cholesterol available for acylCoA:cholesterol acyltransferase (ACAT) was rapidly depleted by adding apoA-I to the medium, and the PKC inhibitor treatment reversed this effect. In contrast, nonspecific cellular cholesterol efflux to the lipid microemulsion did not influence the ACAT-available cellular cholesterol pool, and it was not influenced by the PKC inhibitors. Thus, we concluded that apolipoprotein-mediated cellular cholesterol efflux is linked to mobilization of cholesterol from an intracellular pool used by ACAT to a specific pool for apolipoprotein-mediated prebeta-HDL generation, in response to apolipoprotein-cell interaction and subsequent intracellular signaling. Binding of apolipoprotein to the cell surface is required for assembly of the prebeta-HDL particle with cellular phospholipid, and the intracellular cholesterol mobilization is needed for enrichment with cholesterol of the prebeta-HDL. These reactions are largely independent of diffusion-mediated nonspecific cell cholesterol efflux.
Fabrication of low-loss IR-transmitting Ge/sub 30/As/sub 10/Se/sub 30/Te/sub 30/ glass fibers (1994)

Improved purification and processing techniques have been utilized to fabricate Ge/sub 30/As/sub 10/Se/sub 30/Te/sub 30/ glass fibers with a minimum loss of O.11 dB/m at 6.6 /spl mu/m. This is the lowest loss reported for any telluride glass fiber in the infrared region. Furthermore, the fibers exhibit less than 1 dB/m loss between 5.25 and 9.5 /spl mu/m.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>