gebhart/patrepeval huggingface dataset:
ROLE OF BIOMECHANICAL STIMULATION (CYCLING) IN NEO-BLADDER REGENERATION - TRANSLATIONAL BASIS FOR CLINICAL OUTCOMES (2009)

You have accessJournal of Urology1 Apr 2009ROLE OF BIOMECHANICAL STIMULATION (CYCLING) IN NEO-BLADDER REGENERATION - TRANSLATIONAL BASIS FOR CLINICAL OUTCOMES Elyse Seltzer, Michael Tillinger, Manuel J Jayo, and Timothy A Bertram Elyse SeltzerElyse Seltzer More articles by this author , Michael TillingerMichael Tillinger More articles by this author , Manuel J JayoManuel J Jayo More articles by this author , and Timothy A BertramTimothy A Bertram More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(09)60804-1AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "ROLE OF BIOMECHANICAL STIMULATION (CYCLING) IN NEO-BLADDER REGENERATION - TRANSLATIONAL BASIS FOR CLINICAL OUTCOMES." The Journal of Urology, 181(4S), p. 282 © 2009 by American Urological AssociationFiguresReferencesRelatedDetails Volume 181Issue 4SApril 2009Page: 282 Advertisement Copyright & Permissions© 2009 by American Urological AssociationMetricsAuthor Information Elyse Seltzer More articles by this author Michael Tillinger More articles by this author Manuel J Jayo More articles by this author Timothy A Bertram More articles by this author Expand All Advertisement PDF downloadLoading ...
Density Estimation Using Muon Imaging (2015)

Summary Muons are subatomic particles capable of penetrating the earth’s crust several kilometers. Muons have been used to image the Pyramid of Khafre of Giza, various volcanoes, and smaller targets like cargo. For objects like a volcano, the detector is placed at the volcano’s base and muon fluxes for paths through the volcano are recorded for many days to weeks.
Binding sites for use in a simple assembler (1997)

Machines, both macroscopic and molecular, are made from parts. The initial orientation and positioning of those parts is usually random. To facilitate subsequent parts handling and assembly steps, it is convenient to position and orient the parts. At the molecular scale, this corresponds to binding feedstock molecules dissolved in solvent. In the system design process, the binding site and the feedstock molecule can be designed together, simplifying the design of both. Simple linear molecules (e.g., acetylene, butadiyne, cyanogen) could be bound by simple tubular binding sites (e.g., bucky tubes). Planar rectangular molecules could be bound by simple `box' binding sites. This paper examines several such feedstock-molecule/binding-site combinations to illustrate that the combined design process is feasible and often relatively straightforward.
Review article: fungal alterations in inflammatory bowel diseases (2019)

Gut fungi are altered in patients with Crohn's disease and ulcerative colitis. Modulation of the fungal microbiota can be considered as a therapeutic approach for IBD. Future research should focus on understanding how the fungal microbiota interacts with other components of the gut microbiota in association with the pathogenesis and development of IBD.
Auditory acuity for aircraft in real-world ambient environments (2010)

Although many psychoacoustic studies have been conducted to examine the detection of masked target sounds, the vast majority of these studies have been conducted in carefully controlled laboratory listening environments, and their results may not apply to the detection of real-world sounds in the presence of naturalistic ambient sound fields. Those studies that have examined the detection of realistic naturally-occurring sounds have been conducted in uncontrolled listening environments (i.e., outdoor listening tests) where the experimenters were unable to precisely control, or even measure, the specific characteristics of the target and masker at the time of the detection judgment. This study represents an attempt to bridge the gap between unrealistic laboratory listening studies and uncontrolled outdoor listening studies through the use of pseudorandomly-presented real world recordings of target and masking sounds. Subjects were asked to detect helicopter signals in the context of an ongoing ambient recording in a two interval detection task. The results show that the signal-to-noise ratio required to detect an aircraft sound varies across different types of ambient environments (i.e., rural, suburban, or urban).
ChemInform Abstract: Reactions of Dioxygen Complexes. Oxidative Dehydrogenation of 2‐(Aminomethyl)pyridine Through Cobalt Dioxygen Complex Formation. (1986)

Abstract The reactivity of coordinated dioxygen in dioxygen adducts formed from mixed ligand polyamine complexes of cobalt was studied.
Développement d'un outil métier pour le prédimensionnement de paliers\n élastomèriques (2011)

On presente, dans cette communication,\n l'application des travaux de thèse de S. Lejeunes à savoir des éléments finis réduits\n permettant de modéliser des structures lamifiées élastomère-métal qui sont largement\n utilisés dans les ensembles dynamiques d'hélicoptères (systèmes rotors et suspensions).\n Cette technique, visant à prédire le comportement et la durée de vie de ces composants\n afin de garantir des objectifs de conception exigeants, permet un gain important en\n terme de ressources informatiques tout en offrant une qualité de résultats comparable à\n des modèles classiques.
Synthetic hydrogels for controlled stem cell differentiation (2009)

Stem cells offer great promise for regenerative medicine because of their pluripotency and their ability for self-renewal; however, their use in clinical treatments requires knowledge of the cues that control stem cell fate in vivo, and the ability to recapitulate those cues in tissue-engineered systems to direct differentiation into desired cell types and tissues. Hydrogels formed from poly(ethylene glycol) (PEG) are useful as scaffolds for promoting stem cell growth and differentiation towards the formation of tissues. The mechanical and biochemical microenvironment of these PEG hydrogels can be modified in a variety of ways to control cellular functions that are important in determining and maintaining stem cell phenotype. In this review, recent advances in the synthesis and modification of PEG hydrogels will be presented, along with important physicochemical considerations in the design of these hydrogels to better mimic the stem cell microenvironment and direct stem cell differentiation.
Traumatic Basilar Aneurysm after Endoscopic Third Ventriculostomy: Case Report (1998)

In reply: We appreciate the comments by Vandertop and agree that the laser should be abandoned in neuroendoscopy. Interestingly, we were using a coated laser fiber tip during the third ventriculostomy and still had this complication. Mark R. McLaughlin A. Leland Albright John B. Wahlig Pittsburgh, Pennsylvania
Computer Simulation of the Phase Stabilities of Lithiated TiO<sub>2</sub> Polymorphs (2010)

The structure and phase stability of a series of lithiated titania polymorphs were determined using energy minimizations of the periodic bulk crystal structures and both density functional theory (DFT) and a potential shell model. The DFT calculations were performed spin unrestricted following the linear combination of atomic orbital approach with the B3LYP exchange-correlation potential. For the potential shell model, a new set of force field parameters was derived, independently of the DFT calculations, to describe the lithium−lattice interactions. The eight polymorphs considered in this study are the rutile, anatase, brookite, TiO2−B, ramsdellite, hollandite, spinel, and hexagonal structures. The lithium to titanium ratio, x, of each lithiated titania polymorph was varied from 0.0 to 1.0 with 0.25 increments. The potential model predictions were found to be in good agreement with the structure and energetics of the lithiated titania polymorphs determined from DFT calculations, at all lithium contents. Both computational approaches indicate the following relationships. The naturally occurring titania polymorphs (i.e., rutile, anatase, brookite, and TiO2−B) were found to be the most stable of the eight phases in the absence of lithium. Anatase, brookite, and ramsdellite become energetically favored over rutile upon lithium insertion. The hexagonal and spinel polymorphs have stabilities approaching that of rutile with increasing lithium content and showed essentially equivalent total energies for x = 1.0. This prediction is consistent with numerous experimental studies, which have reported that rutile electrodes, in particular those that consist of nanomaterials, can undergo phase transformations to the hexagonal or spinel structure upon lithium insertion. The calculations indicate that the main factors controlling the relative stability of the lithiated titania polymorphs are the lithium bonding environment, the arrangement of LiOx and TiO6 polyhedra, and the extent of lattice deformation upon lithiation.
Synamon, a Novel Neuronal Protein Interacting with Synapse-associated Protein 90/Postsynaptic Density-95-associated Protein (1999)

Guanylate kinase-associated protein (GKAP)/SAP90/PSD-95-associated protein (SAPAP)/DLG-associated protein (DAP) is a protein of the postsynaptic density (PSD), and binds to the guanylate kinase domain of PSD-95/synapse-associated protein (SAP) 90 and synaptic scaffolding molecule. GKAP/SAPAP/DAP recruits PSD-95/SAP90 and its interacting protein, brain-enriched guanylate kinase-interacting protein, into the Triton X-100-insoluble fraction in transfected cells, suggesting that GKAP/SAPAP/DAP may link several PSD components to the Triton X-100-insoluble structures in the PSD. We have identified here a novel neuronal GKAP/SAPAP/DAP-binding protein and named it synamon. Synamon has seven ankyrin repeats at the NH(2) terminus followed by one src homology 3 domain and one PSD-95/Dlg-A/ZO-1 domain, and several proline-rich regions at the carboxyl terminus. Synamon interacts with the COOH-terminal region of GKAP/SAPAP/DAP via the middle region containing a PSD-95/Dlg-A/ZO-1 domain. Synamon was coimmunoprecipitated with SAPAP from rat crude synaptosomes and colocalized with SAPAP in primary cultured rat hippocampal neurons. Because synamon is composed of various protein-interacting modules, it may also interact with proteins other than GKAP/SAPAP/DAP to organize the architecture of the PSD.
Troubles électrolytiques Secondaires À Une Perfusion Glucosée De Longue Durée (1963)

Chez six chiens, soumis durant quatre à serif, heures à une perfusion glucosée hypertonique, la diurèse hydrique par glycosurie se maiatient, quel que soit l'état de déshydratation. Par contre, l'effet natriurétique et potassurique s'épuise rapidement, en deux à trois heures, pour faire place à une excrétion ionique minime et indépendante du flux urinaire.La phase initiale comporte une hypoélectrolytémie malgré la déplétion hydrique, celle-ci étant d'abord localisée au compartiment cellulaire. Ensuite, tandis que l'hypopotassémie s'accentue, le taux du sodium plasmatique pent revenir aux valeurs initiales, voire les dépasser, secondairement à la déshydratation globale.
Applications of cumulants to array processing: direction-finding in coherent signal environment (2002)

Dogan and Mendel (see IEEE Trans. on Signal Processing, 1994) have developed the virtual-ESPRIT algorithm (VESPA) for direction-finding and recovery of independent sources. VESPA can calibrate an array of unknown configuration and arbitrary response by using just one additional pair of identical sensors (instead of a copy of the entire array or storage of the entire array response for every possible scenario, which is required by existing alternatives). We present an approach that generalizes VESPA to handle the case of highly correlated or coherent sources. Unlike existing methods, our method is not restricted to linear arrays, and no search procedure is needed. Just as in VESPA, it is still possible to detect more sources than sensors, and suppress both Gaussian as well as non-Gaussian noise. A simulation experiment supporting our conclusions is provided.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
APOLAR EMBRYOS OF FUCUS RESULTING FROM OSMOTIC AND CHEMICAL TREATMENT (1970)

Embryos of the brown alga Fucus vesiculosas L. were grown as populations in glass petri dishes in seawater at 15 C in continuous low‐intensity unilateral fluorescent illumination for periods up to 2 weeks. A quantitative estimate of increase in nuclear number was made from acetocarmine squash preparations of samples taken at 12‐or‐24 hr intervals. Over the period of 2‐6 days embryos showed a doubling time of about 12‐18 hr. Under normal seawater culture conditions each embryo formed a single rhizoid. When grown in seawater supplemented with sugar concentrations above 0.4 m , F ucus embryos developed as multicellular spherical embryos lacking rhizoids. In 0.6 m sucrose‐seawater, 97% of the embryos were apolar at 2 days; only 37% were apolar at 4 days, many having recovered from the sucrose inhibition. Some embryos remained apolar after growth in 0.6 m sucrose for 2 weeks. Nuclear counts showed that sucrose‐seawater markedly inhibited the rate of cell division. Other sugars including D‐glucose, D‐fructose, D‐galactose and the sugar alcohol D‐mannitol were also effective. When apolar embryos grown in sucrose‐seawater were returned to seawater, embryo growth resumed at the normal seawater rate, judged from nuclear counts. Such embryos formed multiple rhizoids, varying from two to eight rhizoids per embryo, which developed on the embryo quadrant or half away from the unilateral light. Each of the multiple rhizoids originated from a single small cell in the periphery of the multicellular spherica embryo. Thus the rhizoid‐forming stimulus apparently had been subdivided among a number of the cells of the apolar embryos. The implications of this finding are discussed. Attempts to produce multiple rhizoids by treatment of embryos with indoleacetic acid or 2,4‐dichlorophen‐oxyacetic acid failed. However, embryos treated with 10 −4 M or 5 × 10 −5 m 2,3,5‐triiodobenzoic acid formed 40 and 30% multiple rhizoids, respectively, suggesting that some chemical, perhaps hormonal, mechanism is involved in polarization and rhizoid initiation in Fucus embryogenesis.
Relation Between Troponin T and the Risk of Subsequent Cardiac Events in Unstable Coronary Artery Disease (1996)

Troponin T determination is an inexpensive and widely applicable method for early risk assessment in patients with unstable coronary artery disease. The maximum tn-T value obtained during the first 24 hours provides independent and important prognostic information.
Structural transitions in holographic polymer-dispersed liquid crystals (2004)

Dynamic light scattering was used to analyze the structural and dynamic properties of nematic director field within liquid crystal domains formed in holographic polymer-dispersed liquid crystal transmission gratings. Samples prepared from two different types of prepolymer mixture: one curable with visible (VIS) and another curable with UV light were investigated. In both formulations a critical slowing down of thermal director fluctuations, signifying the second-order structural transition of the nematic director field was observed in the vicinity of some critical external electric field as well as close to some critical temperature. For VIS samples also the size and the shape of phase separated droplets and viscoelastic and surface anchoring parameters of the liquid crystalline (LC) material forming the droplets were deduced. The viscoelastic constants were found to significantly deviate from the viscoelastic parameters of the pure LC mixture.
Zao Ren An Shen capsule for chronic insomnia (2019)

Australia New-Zealand Clinical Trial Registry (Registration number ACTRN12619000140156).
Engineered Schottky barrier diodes for the modification and control of Schottky barrier heights (1987)

A technique for fabricating controlled Schottky barrier heights to GaAs over the entire band gap is demonstrated. Thin, highly doped semiconductor layers at the metal-semiconductor interface allowed the reproducible control of the effective barrier height on n-type GaAs from near zero (i.e., ohmic behavior at 300 K) to 1.33 eV (the band gap equals 1.43 eV at 300 K) with diode ideality factors 1.02≤n≤1.21. Molecular-beam epitaxy was used to grow GaAs epitaxial layers with in situ deposited Al metal layers, resulting in diodes with nearly ideal electrical and structural characteristics. Electrical characterization by current-voltage (I-V) and capacitance-voltage (C-V) techniques, models for these I-V and C-V characteristics, and structural characterization by high resolution transmission electron microscopy lattice images are presented. Implications of this work for models of Schottky barrier formation are discussed, as well as some applications for these ‘‘engineered Schottky barrier diodes.’’
Bacterial attachment and removal properties of silicon- and nitrogen-doped diamond-like carbon coatings (2009)

Si- and N-doped diamond-like carbon (DLC) coatings with various Si and N contents were deposited on glass slides using magnetron sputter ion-plating and plasma-enhanced chemical vapour deposition. Surface energy analysis of the DLC coatings revealed that with increasing Si content, the electron acceptor gamma(s)(+) value decreased while the electron donor gamma(s)(-) value increased. The antifouling property of DLC coatings was evaluated with the bacterium, Pseudomonas fluorescens, which is one of the most common microorganisms forming biofilms on the surface of heat exchangers in cooling water systems. P. fluorescens had a high value of the gamma(s)(-) component (69.78 mN m(-1)) and a low value of the gamma(s)(+) component (5.97 mN m(-1)), and would be negatively charged with the zeta potential of -16.1 mV. The experimental results showed that bacterial removal by a standardised washing procedure increased significantly with increasing electron donor gamma(s)(-) values and with decreasing electron acceptor gamma(s)(+) values of DLC coatings. The incorporation of 2%N into the Si-doped DLC coatings further significantly reduced bacterial attachment and significantly increased ease of removal. The best Si-N-doped DLC coatings reduced bacterial attachment by 58% and increased removal by 41%, compared with a silicone coating, Silastic T2. Bacterial adhesion strength on the DLC coatings is explained in terms of thermodynamic work of adhesion.
Streaming liver VIII: cell production rates following partial hepatectomy (1991)

Twenty-four young, female, random-bred rats weighing 250 g were partially hepatectomized and killed in groups of four animals at the following times: 1 h and 1, 2, 3, 7 and 14 days. One hour before killing, each rat was injected i.p. with 0.5 microCi [3H]-thymidine, specific activity 5 Ci/mmol/g body weight. Livers were processed histologically and dipped into liquid emulsion for autoradiography. Twenty-four hours after partial hepatectomy, hepatocyte and littoral labelling indices rose, reaching on the third day respective peak values of 3.7%, and 15.4%, whereupon they declined, remaining slightly above pre-treatment level. Labelling indices served for cell production estimates. On day 3 the hepatocyte labelling index rose 26-fold. At the same time hepatocytes doubled their ploidy, indicating that half of the observed L.I. increase was directed to DNA accumulation and not to cell division. The hepatocyte production rate therefore increased 13-fold (or 1300%). The acinus diameter increased 15%, and cell density declined 5%, so that the acinus capacity to retain cells increased only 5%. Since the acinus did not enlarge proportionally to cell production, it is concluded that 95% of newly formed cells were eliminated. Partial hepatectomy thus triggers two processes: an acute process lasting about a week marked by massive and rapid cell turnover during which most newly formed cells are eliminated; and a second, more protracted process which serves for liver mass restoration. It is proposed that partial hepatectomy induces an acute shortage of a hitherto unknown metabolite that is produced by newly formed cells immediately after hepatectomy.
Lightness contrast and lightness constancy (1988)

Previous studies of lightness contrast and constancy have used matching procedures to assess perceptual effects. Many experiments indicate that constant luminance ratios give constant lightness matches, suggesting lightness contrast as an explanation of lightness constancy. Other studies fail to support this conclusion. We felt that the contradictory results might be due to the difficulty of making lightness matches in the face of large brightness differences. Thus we had observers make absolute lightness judgments of center-surround targets over a large range of contrast ratios and luminance. We first used brief (300-ms) flashes to keep the eye in a fixed state of light adaptation. The results surprised us. We found that lightness constancy failed for every subject: generally low and high luminances were judged to be blacker than middle luminances for a wide range of contrast ratios. When longer (7-s) flashes were used, however, we obtained good constancy. We then tried brief flashes following light-adapting fields to ascertain if the constancy found for longer flashes could be attributed to adaptation. The results were negative. Our tentative conclusion is that constancy fails for brief flashes due to their transient nature, not to the lack of adaptation. Apparently, sustained viewing is necessary for lightness constancy.
Effect of nifedipine on constriction of human tracheal strips <i>in vitro</i> (1983)

1 Autopsy specimens of human trachealis muscle were used to investigate the effect of the calcium channel blocker, nifedipine, on airway smooth muscle constriction. With these tracheal strips, two consecutive cumulative concentration-effect curves to histamine (0.1-100 microM) obtained at a 60 min interval were highly reproducible. 2 We examined the effects of adding nifedipine (2.9 microM) to the incubation medium before the second histamine response. The concentration-effect relationships determined after nifedipine incubation were significantly different from control: the response to 100 microM histamine was reduced by approximately one-half (to 2.53 +/- 0.6 g; P less than 0.025), and the concentration of histamine causing 40% of the maximal control contraction (EC40) increased nearly ten fold (to 36.9 +/- 10.5 microM; P less than 0.02). 3 In two additional tracheal strips submaximally constricted with 10 microM histamine, nifedipine 2.9 microM caused complete relaxation to resting tension or below. 4 These results indicate a direct inhibitory effect of nifedipine on airway smooth muscle constriction and partial dependence of human trachealis muscle on calcium ion fluxes for initiation and maintenance of contraction. In addition, the results suggest a potential mechanism for the inhibitory effects of calcium channel blocking drugs in exercise-induced asthma.