gebhart/patrepeval huggingface dataset:
SiMPE (2011)

With the proliferation of pervasive devices and the increase in their processing capabilities, client-side speech processing has been emerging as a viable alternative. The SiMPE workshop series started in 2006 [5] with the goal of enabling speech processing on mobile and embedded devices to meet the challenges of pervasive environments (such as noise) and leveraging the context they offer (such as location). SiMPE 2010, the latest in the series brought together, very successfully, researchers from the speech and the HCI communities. We believe this is the beginning.
Direct Measurement of Electron Loss Rate in Air (2010)

We present direct local measurements of electron attachment and recombination rates in atmospheric air. Using a microwave scattering based resonantly enhanced multi-photon ionization scheme we monitor the electron density dynamics with nanosecond resolution.
Circulating Immune Complexes Pre and Post Clotting Factor Infusion in Hemophilia (1981)

Summary Circulating immune complexes (CICs) were studied by the Raji cell radioimmune-assay (Raji-RIA) and Clq-solid phase assay (Clq-SPA) in sera samples obtained pre and post replacement infusion from 21 young hemophiliac patients (Mean age 9.5 years). Seven patients had repeat studies. Sixteen patients were selected randomly; the other five were selected as having potential infusion related disease processes. All patients had received multiple infusions prior to entering the study. Five patients were infused with FIX concentrates (2 Hemophilia B, one FVII deficiency, 2 with inhibitors to FVIII). Of the hemophilia A patients (13 severe; 3 mild/moderate), six were infused with ABO-Rh type specific cryoprecipitate and 10 were infused with factor concentrate. Preinfusion sera samples evaluated by the Raji-RIA showed 14 of 28 (50%) sera positive. Eleven of 28 (39.3 %) were positive post infusion in the Raji-RIA. Pre and post infusion studies of the same sera samples using the Clq-SPA showed 5 of 28 (17.9%) positive pre-infusion and 4 of 28(14.3%) positive post infusion. No statistically significant relationship between pre and post infusion studies could be demonstrated. There was no obvious correlation between CIC levels and patient age, race, Epe of infusate, ABO-Rh blood type, hepatosplenomegaly, the presence or absence of HBsAG, antibody, or chronic joint changes. CICs were detected in the three patients with SGOT/SGPT levels greater than 5 times normal, in both patients with chronic renal disease (chronic glomerulonephritis), and two children who had previously demonstrated a Coombs’-positive hemolytic anemia after factor concentrate infusion. Six of eight patients with extremely high levels of CICs had associated clinical or laboratory abnormalities. This data indicated that CICs (as detected by the Raji-RIA) are present in increased frequency in hemophiliac patients. Although individual patients developed CICs post infusion, there is no clinical or statistical data supporting a common infusate immunogen. CICs were present in patients with serum hepatitis and other immune related disorders, probably secondary to factor infusion. The immunopathogenicity and origin of CICs in hemophiliacs is uncertain.
Microwave Mode Locking at X Band Using Solid-State Devices (1978)

A theory of mode locking in the microwave regime is presented. The use of solid-state microwave devices for this application is described. A system that has been built using an IMPATT diode as the gain element and a Schottky barrier diode in the role of a saturable absorber is analyzed. Passive, combined passive, and forced mode locking have been demonstrated experimentally. The system had a round-trip time of 25 or 50 ns. Pulse lengths between 4 and 15 ns were observed. Self-starting and stability requirements are investigated.
An investigation on diffusion bonding of aluminum to copper using equal channel angular extrusion process (2011)

A new method for production of bimetallic rods, utilizing the equal channel angular extrusion (ECAE) process has been introduced before by previous researchers, but no attempt has been made to assess the effect of different temperatures and holding times in order to achieve a diffusional bond between the mating surfaces. In present research copper sheathed aluminum rods have been ECAEed at room temperature and subsequently held at a constant ECAE pressure, at different temperatures and holding times to produce a diffusional bond between the copper sheath and the aluminum core. The bonding quality of the joints was examined by shear strength test and a sound bonding interface was achieved. Based on the results, a bonding temperature of 200 °C and holding time of 60-80 min yielded the highest shear strength value.
Observation of Autoionization Suppression through Coherent Population Trapping (1995)

The strong electromagnetic coupling of two autoionizing states is experimentally investigated for the first time and is shown to lead to coherent population trapping resulting in a reduction of the ionization. The experimental observation of partial stabilization is supported by a theoretical analysis which reproduces the modification of the Fano profiles and indicates that the strong coupling of the two states leads to the trapping of the population in the ground state of the atom.
Effect on survival after myocardial infarction of long-term treatment with phenytoin. (1978)

A prospective, randomised, open trial was performed in 150 patients to test for any beneficial effects on 2-year mortality of long-term antiarrhythmic therapy with phenytoin in patients with acute myocardial infarction. Patients were stratified according to age, sex, past history of myocardial infarction, and the presence of absence of electrical or mechanical complications in the course of acute infarction. They were then randomised to treatment or control groups (74 v. 76). The former received phenytoin in doses aimed at maintaining plasma phenytoin levels between 40 and 80 mumol/litre. All patients entered the study before discharge from the coronary care ward. Plasma phenytoin levels were in the therapeutic range in between 51 and 75 per cent of subjects at any follow up visit. There were 19 withdrawals from the treatment group, 10 of which were the result of side effects. There were 5 withdrawals from the control group. According to the original intention to treat, there were 18 deaths at 2 years in the treatment group and 14 deaths in the control group. There was no reduction in the incidence of instantaneous or sudden deaths. Deaths on treatment were not associated with a low phenytoin plasma level. Phenytoin treatment showed no beneficial effects on mortality and was associated with a high incidence of side effects.
Synthesis of transforming growth factor-beta 1 by megakaryocytes and its localization to megakaryocyte and platelet alpha-granules (1990)

We have directly demonstrated that megakaryocytes are a major site of synthesis and storage of transforming growth factor-beta 1 (TGF/beta 1) by combined immunohistochemical, immunocytochemical, and in situ hybridization methods. The presence of TGF/beta 1 messenger RNA (mRNA) in mature megakaryocytes in adult rat spleen and bone marrow (BM) was established by in situ hybridization. Localization of TGF/beta 1 protein to intact alpha-granules of megakaryocytes, its putative storage site, was accomplished in glycol-methacrylate embedded porcine BM with an immunoperoxidase technique and light microscopy. The TGF/beta 1 was sequestered in intracytoplasmic granules in a pattern virtually identical to that of another alpha-granule marker protein, fibrinogen. This observation strongly suggests packaging of TGF/beta 1 into this organelle within megakaryocytes. That TGF/beta 1 mRNA was localized to megakaryocytes suggests that the TGF/beta 1 found in the alpha-granules in platelets originates with megakaryocyte synthesis. The alpha-granule localization of TGF/beta 1, as well as fibrinogen, was also demonstrated in isolated platelets at the ultrastructural level by electronmicroscopy (EM) and postembedding colloidal-gold immunocytochemistry, thus directly demonstrating that alpha-granules are the final storage site for TGF/beta 1 in mature platelets.
Laser damage threshold measurements of anti-reflection microstructures operating in the near UV and mid-infrared (2010)

Surface relief textures fabricated in optical components can provide high performance optical functionality such as antireflection (AR), wavelength selective high reflection, and polarization filtering. At the Boulder Damage XXXIX symposium in 2007, exceptional pulsed laser damage threshold values were presented for AR microstructures (ARMs) in fused silica measured at five wavelengths ranging from the near ultraviolet (NUV) to the near infrared. For this 2010 symposium, NUV pulsed laser damage measurements were made for ARMs built in fused silica windows in comparison to untreated fused silica windows. NUV threshold values are found to be comparable for both ARMs-treated and untreated windows, however the threshold level was found to be strongly dependent on the material and surface preparation method. Additional infrared wavelength damage testing was conducted for ARMs built in four types of mid-infrared transmitting materials. Infrared laser damage threshold values for the ARMs treated windows, was found to be up to two times higher than untreated and thin-film AR coated windows.
Immunological mechanisms of the antitumor effects of supplemental oxygenation (2015)

Antitumor T cells either avoid or are inhibited in hypoxic and extracellular adenosine-rich tumor microenvironments (TMEs) by A2A adenosine receptors. This may limit further advances in cancer immunotherapy. There is a need for readily available and safe treatments that weaken the hypoxia-A2-adenosinergic immunosuppression in the TME. Recently, we reported that respiratory hyperoxia decreases intratumoral hypoxia and concentrations of extracellular adenosine. We show that it also reverses the hypoxia-adenosinergic immunosuppression in the TME. This, in turn, stimulates (i) enhanced intratumoral infiltration and reduced inhibition of endogenously developed or adoptively transfered tumor-reactive CD8 T cells, (ii) increased proinflammatory cytokines and decreased immunosuppressive molecules, such as transforming growth factor-β (TGF-β), (iii) weakened immunosuppression by regulatory T cells, and (iv) improved lung tumor regression and long-term survival in mice. Respiratory hyperoxia also promoted the regression of spontaneous metastasis from orthotopically grown breast tumors. These effects are entirely T cell- and natural killer cell-dependent, thereby justifying the testing of supplemental oxygen as an immunological coadjuvant to combine with existing immunotherapies for cancer.
Infection with recombinant orf viruses demonstrates that the viral interleukin-10 is a virulence factor (2007)

Orf virus is the prototype parapoxvirus that causes the contagious skin disease orf. It encodes an orthologue of the cytokine interleukin (IL)-10. Recombinant orf viruses were constructed in which the viral interleukin-10 (vorfIL-10) was disabled (vorfIL-10ko) and reinserted (vorfrevIL-10) at the same locus and compared to wild-type virus for their ability to induce skin lesions in sheep. After either primary infection or reinfection, smaller less severe lesions were recorded in the vorfIL-10ko-infected animals compared with either of the vorfIL-10-intact virus-infected animals. Thus, the vorfIL-10ko virus was attenuated compared with the vorfIL-10 intact viruses, demonstrating that orf virus IL-10 is a virulence factor. The virus IL-10 is one of several virulence or immuno-modulatory factors expressed by orf virus. Removal of any one of these genes would be expected to have only a partial effect on virulence, which is what was observed in this study with vorfIL-10.
Time Domain Impedance Spectroscopy for Probing the Termination of Silicon (100) Surfaces in Aqueous KOH (2001)

Time domain impedance spectroscopy (TDIS), potential step experiments, and in-situ infrared spectroscopy (FTIR) have been used to probe the surface termination of silicon (100) in contact with aqueous potassium hydroxide. TDIS allowed time-dependent measurements of the space charge capacitance with a time resolution of ∼100 μs and was used to probe the interfacial potential and charge distribution. From this, an analysis of the surface termination could be made. For p-Si(100) these measurements suggest that the hydrogen termination present at negative potentials is replaced by polar Si−O−Si bridges between neighboring surface silicon atoms at anodic peak potentials. The changes in surface termination have a time constant of ∼1 s, which is slow compared with the time resolution of TDIS. Time-resolved Mott−Schottky plots could be constructed for both p- and n-Si(100). A flat band potential of −0.55 V was obtained for p-Si(100). For n-Si(100), the technique allowed space charge capacitance measurements that were sufficiently short to obviate surface passivation. Therefore, space charge capacitance measurements could be extended far into the passive potential range, from which a flat band potential of −0.85 V vs SCE was obtained.
Scattering Induced Quantum Interference of Multiple Quantum Optical States (2011)

Using a discrete mode theory for propagation of quantum optical states, we investigate the consequences of multiple scattering on the degree of quadrature entanglement and quantum interference. We report that entangled states can be created by multiple‐scattering. We furthermore show that quantum interference induced by the transmission of quantized light through a multiple‐scattering medium will persist even after averaging over an ensemble of scattering samples.
Cocaine Addiction: Psychology and Neurophysiology (1991)

Cocaine was considered incapable of producing dependence in 1980 but was recently proclaimed the drug of greatest national health concern. Recent clinical and preclinical investigations demonstrate that cocaine produces unique abuse and withdrawal patterns that differ from those of other major abused drugs and suggest that long-term cocaine abuse produces neurophysiological alterations in specific systems in the central nervous system that regulate the capacity to experience pleasure. It will be necessary to develop clinically pertinent research models before these findings can be considered definitive, but these evolving ideas have already led to applications of promising experimental treatments for cocaine abuse.
Analysis of Conformational Coverage. 2. Applications of Conformational Models (1995)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAnalysis of Conformational Coverage. 2. Applications of Conformational ModelsAndrew Smellie, Scott D. Kahn, and Steven L. TeigCite this: J. Chem. Inf. Comput. Sci. 1995, 35, 2, 295–304Publication Date (Print):March 1, 1995Publication History Published online1 May 2002Published inissue 1 March 1995https://pubs.acs.org/doi/10.1021/ci00024a019https://doi.org/10.1021/ci00024a019research-articleACS PublicationsRequest reuse permissionsArticle Views188Altmetric-Citations128LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
The Family Cymatiidae in the Western Atlantic (1957)

(Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
Novel Miscible Polymer Blend of Poly(4-trimethylsilylstyrene) and Polyisoprene (2005)

The phase behavior of the newly found miscible polymer blends poly(4-trimethylsilylstyrene) and polyisoprene was investigated with optical microscopy (OM) and also with differential scanning calorimetry (DSC), while the degree of polymer−polymer interaction was evaluated with small-angle neutron scattering (SANS). The blends with homogeneous one phase at various compositions turned into two phases by heating, showing a lower critical solution temperature (LCST) type phase diagram with a critical temperature of 172 °C if the degree of polymerization is ca. 370. The blend gave a single glass transition temperature below the LCST, and the interaction parameter χ was represented as a function of temperature T according to the relationship χ = 0.027 − 9.5/T.
Evaluation of Cerebrovascular Impedance and Wave Reflection in Mouse by Ultrasound (2014)

Genetic and surgical mouse models are commonly used to study cerebrovascular disease, but their size makes invasive hemodynamic testing technically challenging. The purpose of this study was to demonstrate a noninvasive measurement of cerebrovascular impedance and wave reflection in mice using high-frequency ultrasound in the left common carotid artery (LCCA), and to examine whether microvascular changes associated with hypercapnia could be detected with such an approach. Ten mice (C57BL/6J) were studied using a high-frequency ultrasound system (40 MHz). Lumen area and blood flow waveforms were obtained from the LCCA and used to calculate pulse-wave velocity, input impedance, and reflection amplitude and transit time under both normocapnic and hypercapnic (5% CO2) ventilation. With hypercapnia, vascular resistance was observed to decrease by 87%±12%. Although the modulus of input impedance was unchanged with hypercapnia, a phase decrease indicative of increased total arterial compliance was observed at low harmonics together with an increased reflection coefficient in both the time (0.57±0.08 versus 0.68±0.08, P=0.04) and frequency domains (0.62±0.08 versus 0.73±0.06, P=0.02). Interestingly, the majority of LCCA blood flow was found to pass into the internal carotid artery (range=76% to 90%, N=3), suggesting that hemodynamic measurements in this vessel are a good metric for intracerebral reactivity in mouse.
Helicobacter pylori (2014)

Helicobacter pylori is extraordinary among bacteria in its ability to colonize the stomachs of more than half of all people worldwide and often to persist for years or decades once it has become established. H. pylori can be detected and analyzed by a variety of different methods. Seroepidemiological studies performed in the United States and abroad have demonstrated the worldwide presence of H. pylori in a large majority of individuals from low socioeconomic groups and also in many people of higher socioeconomic status. The recent observation that H. pylori can be isolated from cats and that cats can be colonized by H. pylori following inoculation suggests that transmission from pets to humans (or humans to pets) is also possible. The presence of H. pylori can be diagnosed from gastric-biopsy specimens harvested at endoscopy. Long-term gastric colonization is associated with intense humoral and cellular immune responses. However, these responses are usually unable to eradicate H. pylori and they may, in fact, play a role in the persistence of the bacterium and/or in the production of disease. Interestingly, vaccination can reduce the severity of antral gastritis in mice, ferrets, and monkeys. However, immunization can eliminate colonization by H. pylori in mice and ferrets but not in monkeys or humans. The immune response to colonization by H. pylori has been proposed as being responsible in part for the production of peptic ulcer disease (PUD).
Copy of Pulsed Pyroelectric Crystal-Powered Gamma Source. (2012)

Abstract not provided.
Depletion of T cells from human bone marrow with monoclonal antibody CT-2 and complement. (1984)

CT-2 mouse monoclonal antibody to the E-rosette receptor was used with complement to deplete bone marrow of E-rosette-positive cells (T cells). Depletion of E-rosette-positive cells was complete and nontoxic to hematopoietic progenitor cells. Depletion of E-rosette-positive cells with CT-2 may decrease the severity of graft-versus-host disease following bone marrow transplantation and extend the application of bone marrow transplantation to those without HLA-identical donors.
Colonic Kaposiʼs Sarcoma and Diffuse Large B Cell Lymphoma in a Patient with CVID-Associated Enteropathy (2009)

Purpose: 44-year-old man who was well until his 20s when he developed repeated parasitic infections and was diagnosed with common variable immunodeficiency (CVID). Eight years ago, he was started on IVIG because of abdominal pain and diarrhea with patchy active inflammation seen on colonoscopy. His symptoms were relatively well controlled until one year ago when his abdominal pain became more constant and severe. An infectious workup was negative and he had a colonoscopy, which showed scattered inflammation throughout the colon. He was started on oral mesalamine in addition to the IVIG infusions without improvement. One year later, he continued to have abdominal pain as well as frequent loose bowel movements with ongoing weight loss. He was noted to have splenomegaly and lymphadenopathy on exam. He was also pancytopenic with a CD4 count of 179; HIV antibody was negative. An EGD revealed normal appearing duodenal mucosa, and a colonoscopy demonstrated patchy active inflammation throughout the colon with deep ulcers in the sigmoid colon. Duodenal biopsies revealed mild villous blunting as well as intraepithelial lymphocytosis with a paucity of plasma cells consistent with the previous diagnosis of CVID-associated enteropathy. Colon biopsies revealed viral inclusions on H + E stain with positive immunohistochemical staining for CMV. Additionally, a submucosal nodule revealed monomorphic spindle cells arranged in an ill-defined fascicles with extravasated red blood cells. Spindle cells showed nuclear reactivity with HHV-8, establishing the diagnosis of Kaposi's sarcoma (KS). He subsequently underwent a colectomy with an ileorectal anastamosis. Pathologic examination of the colon revealed both diffuse large B cell lymphoma and multiple foci of KS. The endoscopic appearance of CVID-associated enteropathy can be indistinguishable from inflammatory bowel disease. Approximately 25% of patients with CVID also have low CD4 cell counts. It has been reported that patients with CVID have up to a 5-fold risk of malignancy, most commonly lymphoma. Up to 40% of patients with KS have gastrointestinal involvement. The endoscopic finding most commonly reported in association with KS is hemorrhagic nodules. Gastrointestinal KS is typically asymptomatic, although patients may develop GI bleeding, obstruction or perforation. This is the first reported case of CVID with GI involvement complicated by colonic KS. There have been 6 case reports in the literature of visceral KS in patients with hypogammaglobulinemia. However, none of these patients was diagnosed with CVID and none had KS which involved the GI tract. Clinicians and pathologists should be aware of this potential complication in this rare disorder.