gebhart/patrepeval huggingface dataset:
HealthKiosk: A family-based connected healthcare system for long-term monitoring (2011)

In this paper, we present “HealthKiosk”, a family-based healthcare system, to provide rich contextual information and alerting mechanisms for continuous monitoring of health conditions. HealthKiosk significantly improves the reach and quality of regional and community healthcare services, and could potentially minimize the efforts of care professionals for the chronical illness, not only applicable for the elderly but also children and young fitness trainers. The proposed architecture leverages the RESTful design style, nevertheless introducing a novel development of the “sensor proxy”, both in a stationary PC style and as a mobile widget. The sensor proxy behaves not only as a bridge between the raw sensor readings and the kiosk controller, but also as a data processing logic to integrate, correlate, and transform a variety of data from multiple data sources to an integrated XML format. We demonstrate the system performance by showing two complete case studies for both stationary and mobile sensor proxies used in the developed HealthKiosk system. Finally, the proposed solution has been piloted and deployed at the Peking University People's Hospital (PKUPH) for diabetes patients, via building an evidence-based clinical care solution focusing on chronic disease management in China.
Mechanisms of DNA Demethylation in Chicken Embryos (1995)

We have previously shown that in developing chicken embryos and differentiating mouse myoblasts, the demethylation of 5-metCpGs occurs through the replacement of 5-methylcytosine by cytosine (Jost, J. P. (1993) Proc. Natl. Acad. Sci. U.S.A. 90, 4685-4688; Jost, J. P. & Jost, Y.C. (1994) J. Biol. Chem. 269, 10040-10043). We have now purified over 30,000-fold a 5-methylcytosine-DNA glycosylase from 12-day-old chicken embryos. The enzyme copurifies with a mismatch-specific thymine-DNA glycosylase and an apyrimidic-endonuclease. The reaction product of the highly purified 5-methylcytosine-DNA glycosylase is 5-methylcytosine. The copurified apyrimidic-endonuclease activity cleaves 3' from the apyrimidic sugar. A 52.5-kDa peptide, isolated as a single band from preparative SDS-polyacrylamide gels, has both the 5-methylcytosine-DNA glycosylase and the mismatch-specific thymine-DNA glycosylase activities. 5-Methylcytosine-DNA glycosylase has an apparent pI of 5.5-7.5 and maximal activity between pH 6.5 and 7.5. The Km for hemimethylated oligonucleotide substrate is 8 x 10(-8) M with a Vmax of 4 x 10(-11) mol/h/micrograms proteins. 5-Methylcytosine-DNA glycosylase binds equally well to methylated and non-methylated DNA. The enzyme reacts six times faster with the hemimethylated DNA than with the same bifilarly methylated DNA sequence, and single-stranded methylated DNA is not a substrate. The action of the enzyme is distributive.
Aqueous humor lidocaine concentrations in topical and intracameral anesthesia (1998)

Measurable amounts of lidocaine entered the anterior chamber in topical anesthesia, and more entered when more drops were given. It is likely that concentrations in this range could anesthetize the iris, but they are far lower than concentrations after an intracameral injection.
ANTIBODIES AGAINST RNA (2007)

RETURN TO ISSUEPREVNewsNEXTANTIBODIES AGAINST RNABIOCHEMISTRY: Library method to generate antibodies is widely applicableCARMEN DRAHLCite this: Chem. Eng. News 2007, 85, 52, 10Publication Date (Print):December 24, 2007Publication History Published online29 October 2010Published inissue 24 December 2007https://pubs.acs.org/doi/10.1021/cen-v085n052.p010https://doi.org/10.1021/cen-v085n052.p010newsACS PublicationsCopyright © 2007 AMERICAN CHEMICAL SOCIETYArticle Views21Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options SUBJECTS:Biopolymers,Genetics,Immunology,Peptides and proteins Get e-Alerts
Constructing thioether‐tethered cyclic peptides via on‐resin intra‐molecular thiol–ene reaction (2016)

Thiol-ene reactions have been used in a variety of applications that mostly involve an inter-molecular pathway. Herein, we report a facile method to construct thioether-tethered cyclic peptides via an intra-molecular thiol-ene reaction. This reaction is efficient, selective, and has good residue compatibility. Short peptides with thioether tethers were constructed and were used to construct longer cyclic peptides. This synthetic method may be useful for constructing bioactive peptides. Copyright © 2016 European Peptide Society and John Wiley & Sons, Ltd.
King 3 : will it strengthen corporate governance? (2009)

What does King 3 mean in the Local Government Arena? The concept of corporate governance is often mentioned as the latest buzz word with little true understanding of its meaning or intent. Essentially governance is all about transparency and accountability. As the board of an organisation is accountable to their shareholders, our councils and councillors are accountable to the community which they have been elected to. It is management's responsibility to ensure that there is a mechanism or mechanisms in place for the measurement of accountability and transparency. The results of incorporating these principles into our municipalities will ensure that trust is built between local government and their constituents.
User-centered evaluation of interactive question answering systems (2006)

We describe a large-scale evaluation of four interactive question answering system with real users. The purpose of the evaluation was to develop evaluation methods and metrics for interactive QA systems. We present our evaluation method as a case study, and discuss the design and administration of the evaluation components and the effectiveness of several evaluation techniques with respect to their validity and discriminatory power. Our goal is to provide a roadmap to others for conducting evaluations of their own systems, and to put forward a research agenda for interactive QA evaluation.
Surface modification of plastics by plasma treatment and plasma polymerization and its effect on adhesion (1993)

Abstract The Adhesion between plasma‐modified polyethylene (PE) and different polar polymers, as well as aluminium and steel, has been studied. The PE was modified by either oxygen plasma treatment or plasma polymerization of acrylic acid. The result show the importance of introducing polar groups on the surface of the non‐polar PE in order to improve the adhesion to polar polymers as well as metals. Laminates made of plasma‐modified PE ad polyamide 6 (PA‐6) or poly(ethylene vinyl alcohol) (EVAL‐G) showed failure in PA‐6 or EVAL‐G when delaminated. Poly(ethylene terephthalate) (PET), which is not as polar as PA‐6 or EVAL‐G, showed an adhesive failure when the PE was treated with either of the plasma methods. However, when both the PET and the PE were modified, the failure occurred in the PET upon delamination. Oxygen plasma treatment of PE resulted in an increased adhesion when laminated with cellophane, with no observed material failure. The laminates composed of plasma‐modified PE and aluminium or steel showed cohesive failure in the PE.
Preparation of Silver–Gold Alloy Nanoparticles at Higher Concentration Using Sodium Dodecyl Sulfate (2008)

Highly stable gold–silver alloy nanoparticles with varying mole fractions were prepared in aqueous sodium dodecyl sulfate solution by simultaneous reduction of chloroauric acid (HAuCl4) and silver nitrate (AgNO3) using sodium citrate. The formation of alloy nanoparticles was confirmed by UV-visible spectroscopy and transmission electron microscopy. Particle size distribution was measured by dynamic light scattering. The surface plasmon absorption band of the Au–Ag alloy nanoparticles shows linear bathochromic shift with increasing Au content. Appearance of a single absorption peak in the visible region and lack of apparent core-shell structures in the transmission electron microscope images confirm the formation of homogeneous gold–silver alloy nanoparticles.
Three-dimensional magnetic resonance images of the brain: application to neurosurgical planning (1990)

Data from single 10-minute magnetic resonance scans were used to create three-dimensional (3-D) views of the surfaces of the brain and skin of 12 patients. In each case, these views were used to make a preoperative assessment of the relationship of lesions to brain surface structures associated with movement, sensation, hearing, and speech. Interactive software was written so that the user could "slice" through the 3-D computer model and inspect cross-sectional images at any level. A surgery simulation program was written so that surgeons were able to "rehearse" craniotomies on 3-D computer models before performing the actual operations. In each case, the qualitative accuracy of the 3-D views was confirmed by intraoperative inspection of the brain surface and by intraoperative electrophysiological mapping, when available.
Singular value decomposition for the cone-beam transform in the ball (2014)

Abstract The X -ray computerized tomography is concerned to the reconstruction of a function f from line (ray) integrals of f . In general, we may have the parallel ray or divergent ray geometry. In this paper we develop an analytical singular value decomposition method for the cone-beam transform in divergent ray geometry. For the parallel ray transform a singular value decomposition has been derived by P. Maass in 1987.
Population Genetics of<i>Caenorhabditis elegans</i>: The Paradox of Low Polymorphism in a Widespread Species (2003)

Caenorhabditis elegans has become one of the most widely used model research organisms, yet we have little information on evolutionary processes and recent evolutionary history of this widespread species. We examined patterns of variation at 20 microsatellite loci in a sample of 23 natural isolates of C. elegans from various parts of the world. One-half of the loci were monomorphic among all strains, and overall genetic variation at microsatellite loci was low, relative to most other species. Some population structure was detected, but there was no association between the genetic and geographic distances among different natural isolates. Thus, despite the nearly worldwide occurrence of C. elegans, little evidence was found for local adaptation in strains derived from different parts of the world. The low levels of genetic variation within and among populations suggest that recent colonization and population expansion might have occurred. However, the patterns of variation are not consistent with population expansion. A possible explanation for the observed patterns is the action of background selection to reduce polymorphism, coupled with ongoing gene flow among populations worldwide.
PID-Like Neural Network Nonlinear Adaptive Control for Uncertain Multivariable Motion Control Systems (2009)

A mix locally recurrent neural network was used to create a proportional-integral-derivative (PID)-like neural network nonlinear adaptive controller for uncertain multivariable single-input/multi-output system. It is composed of a neural network with no more than three neural nodes in hidden layer, and there are included an activation feedback and an output feedback, respectively, in a hidden layer. Such a special structure makes the exterior feature of the neural network controller able to become a P, PI, PD, or PID controller as needed. The closed-loop error between directly measured output and expected value of the system is chosen to be the input of the controller. Only a group of initial weights values, which can run the controlled closed-loop system stably, are required to be determined. The proposed controller can update weights of the neural network online according to errors caused by uncertain factors of system such as modeling error and external disturbance, based on stable learning rate. The resilient back-propagation algorithm with sign instead of the gradient is used to update the network weights. The basic ideas, techniques, and system stability proof were presented in detail. Finally, actual experiments both of single and double inverted pendulums were implemented, and the comparison of effectiveness between the proposed controller and the linear optimal regulator were given.
Molecular weight dependence of the heats of hydration of some oligomeric ethylene oxides and their methoxyl derivatives (1993)

Abstract The molecular weight dependence of the heat of hydration of the oligomeric ethylene oxides and their monomethoxyl and dimethoxyl derivatives has been studies using microcalorimetry. In all cases the molar heat of hydration decreased rapidly at low molecular weights reaching an asymptote at molecular weights in excess of 400. Equivalent values were obtained between oligomers and blends of the same average molecular weight. The data followed the Flory relationship relating the property of a polymer to the reciprocal of its molecular weight. However, the gradient for the oligomeric ethylene oxides was different from that of the two methoxyl derivatives suggesting a change in chain configuration. © 1993 John Wiley & Sons, Inc.
Novel concept for coherent scatter x-ray computed tomography in medical applications (2000)

We demonstrate for the first time the feasibility of Coherent Scatter Computed Tomography (CSCT) with a fan geometry primary beam. CSCT allows superior tissue characterization and diagnosis by reconstructing the structure function rather than the attenuation properties as in regular CT. To study the feasibility of CSCT, Monte-Carlo based simulations of scatter distributions of technical phantoms were carried out. The projection data were used as input fro a novel algebraic reconstruction technique which takes account of the details of the measurement geometry. First results are discussed showing the potential of CSCT. The influence of achievable angular collimation quality is investigated and an outlook on future work is given.
A study of back-propagation and radial basis neural network on EMG signal classification (2009)

Neural networks are ubiquitous tool for classification. This paper presents a study of classifying EMG signal patterns using back-propagation and radial basis neural networks. Since the pattern of the EMG signal elicited may differ depending on the activity of the muscle movement. Therefore, the purpose of this study was to demonstrate the effectiveness of the neural networks on discriminating the patterns of certain activities to their respective category. Experiments were carried out on a selected muscle. Five subjects were asked to perform several series of voluntary movement with the respect to the muscle concerned. From the EMG data obtained, four statistical features are computed and are applied to the networks. Comparison is made based on the elements of the networks and the classification rate achieved. Generally, both networks are well performed in discriminating different EMG signal patterns with the successful rate of 88% and 89.33% respectively.
Ring‐opening nucleophilic alkylations by tertiary azetidines (1969)

Abstract N ‐Alkylazetidines were cleaved by nucleophilic reagents under moderate conditions to give the corresponding 3‐substituted‐propylamines. The additions were subject to acid catalysis and also proceeded slowly under alkaline S conditions.
Block implementation of adaptive digital filters (1981)

Block digital filtering involves the calculation of a block or finite set of filter outputs from a block of input values. This paper presents a block adaptive filtering procedure in which the filter coefficients are adjusted once per each output block in accordance with a generalized least mean-square (LMS) algorithm. Analyses of convergence properties and computational complexity show that the block adaptive filter permits fast implementations while maintaining performance equivalent to that of the widely used LMS adaptive filter.
An Educated People, a Stronger Society, a Stronger Country (2007)

My name is Kyra Smith, and I am a graduate of Orangeburg-
A research on the storage structure and reconstruction algorithm of Meta data during the startup process of solid state storage systems (2013)

The Meta data structure stored in the flash array can be used to make addressing for the data stored in the system and to obtain the dynamic property parameters of NAND flash. The meta data structure will be reconstructed during the startup period of the solid storage system. The procedure of data reading and writing to the solid storage system can be supported by the meta data structure. The Meta data storage structure in the flash chip for persistence and the corresponding reconstruction approach for large scale flash array are researched in this paper. To make sure the effectiveness of the approach and the quickly reconstruction progress, the solid storage system architecture and storage style of meta data are both studied, and a reconstruction algorithm is presented. The totally reading and partly reconstruction approach is created by author. For the Meta data stored in the flash array, it is once loaded into RAM. When some logical area is accessed by the system, the corresponding meta structure of the area will be reconstructed. According to the software simulation and real circuit verification, the approach presented in this paper can not only accomplish startup procedure quickly, and make the meta data ready, but also the refresh of the meta data during the operation of the storage system makes less writing bandwidth and system overhead. The meta data structure and reconstruction algorithm presented in this paper can be used to large scale flash array, and the storage overhead to the storage system is lower, with fast reconstruction procedure.
Treatment Planning for Conformal Proton Radiation Therapy (2003)

Clinical results from various trials have demonstrated the viability of protons in radiation therapy and radiosurgery. This has motivated a few large medical centers to design and build expensive hospital based proton facilities based proton facilities (current cost estimates for a proton facility is around 100 million US dollars). Until this development proton therapy was done using retrofitted equipment originally designed for nuclear experiments. There are presently only three active proton therapy centers in the United States, 22 worldwide. However, more centers are under construction and being proposed in the US and abroad. The important difference between proton and x-ray therapy is in the dose distribution. X-rays deposit most of their dose at shallow depths of a few centimeters with a gradual decay with depth in the patient. Protons deliver most of their dose in the Bragg peak, which can be delivered at most clinically required depths followed by a sharp fall-off. This sharp falloff makes protons sensitive to variations in treatment depths within patients. Treatment planning incorporates all the knowledge of protons into a process, which allows patients to be treated accurately and reliably. This process includes patient immobilization, imaging, targeting, and modeling of planned dose distributions. Although the principles are similar to x-ray therapy some significant differences exist in the planning process, which described in this paper. Target dose conformality has recently taken on much momentum with the advent of intensity modulated radiation therapy (IMRT) with photon beams. Proton treatments provide a viable alternative to IMRT because they are inherently conformal avoiding normal tissue while irradiating the intended targets. Proton therapy will soon bring conformality to a new high with the development of intensity modulated proton therapy (IMPT). Future challenges include keeping the cost down, increasing access to conventional proton therapy as well as the clinical implementation of IMPT. Computing advances are making Monte Carlo techniques more accessible to treatment planning for all modalities including proton therapy. This technique will allow complex delivery configurations to be properly modeled in a clinical setting.
Novel Biomarkers in Heart Failure: An Overview (2009)

Heart failure is a complex systemic syndrome resulting from significant impairment of cardiac function. A vast array of biological pathways is now known to be involved in heart failure, including deleterious pathways promoting its development and progression, as well as compensatory cardioprotective pathways. Some of the components of these pathways are now recognized as biomarkers of this condition, and can aid diagnosis, prognostication and guide management. As the understanding of the pathophysiology of heart failure progresses, further candidate biomarkers are being identified. This article reviews the literature regarding the more recently identified biomarkers and outlines areas requiring further study.
The Effect of Pasteurization, Selected Additives and Freezing Rate on the Gelation of Frozen-Defrosted Egg Yolk (1968)

EGG yolk becomes an extremely viscous, rubbery mass when frozen to — 6°C. or below and defrosted. The irreversible increase in apparent viscosity of yolk is referred to as gelation. The mechanism responsible for gelation has not been determined. However, lipovitellin, the most abundant lipoprotein in yolk, is implicated in most theories. The tenuous forces binding lipid and protein moieties of lipoproteins like lipovitellin may be disrupted in the frozen state (Lovelock, 1957). Rearrangement and aggregation of yolk lipoproteins may result from the breakdown on freezing of water shells surrounding the protein molecules (Powrie et al., 1963). Gelation was reduced by sodium chloride (Marion and Stadelman, 1958; Powrie et al., 1963; Meyer and Woodburn, 1965) and by sugars as sucrose, fructose, arabinose, and galactose (Pearce and Lavers, 1949; Lopez et al., 1954; Marion and Stadelman, 1958; Meyer and Woodburn, 1965). Egg yolk had nearly normal fluidity when incubated with crotoxin (a . . .