gebhart/patrepeval huggingface dataset:
A review of blepharochalasis and other causes of the lax, wrinkled eyelid. (1990)

Cosmetically unappealing lax, wrinkled eyelid skin may result from various processes including connective tissue diseases, natural aging, and blepharochalasis. Since the end-stage eyelid changes due to several different processes are similar, the presence or absence of prior chronic or recurrent eyelid edema is an important differentiating point. We review blepharochalasis and provide a logical approach to its differential diagnosis.
Chemical inhibition of Plaque (1980)

Attempts to control plaque by chemical means using enzymes, antibiotics and antiseptics are reviewed. Enzymes such as mucinase, dehydrated pancreas, enzymes of fungal origin, dextranase and mutanase showed limited clinical success despite promising in vitro and animal studies. Side effects from the use of enzymes were observed. Many antibiotics have been used in attempts to control plaque and several have been successful. However, problems exist from the long-term use of such drugs which precludes their routine use as agents for controlling plaque. The biguanide chlorhexidine is the most widely used and investigated method of chemical plaque control. Many studies have been demonstrated that it will successfully control plaque. No toxic side effects have been reported from its long-term use but local side effects such as staining of the teeth do occur. The quaternary ammonium compounds have at present no advantages over the biguanides and require more frequent usage to achieve the same degree of plaque control as chlorhexidine.
The Art Therapist: A New Breed Of Teacher (1980)

(1980). The Art Therapist: A New Breed Of Teacher. Action in Teacher Education: Vol. 2, Changing Realities in Teacher Education, pp. 55-56.
Auditing Firms' Fraud Risk Assessment Practices (2001)

The effectiveness of audits in detecting fraudulent misstatements in financial statements is of major concern to the auditing profession. This concern led to the issuance of Statement on Auditing Standards (SAS) No. 82, which made several changes in the manner in which auditors are required to consider the risk of material misstatements due to fraud. This manuscript reports the results of a study of the practices of CPA firms in implementing SAS No. 82. We compared audit manuals and practice aids and interviewed firm personnel from all of the Big 5 firms and two second-tier firms. Results of this study indicate that audit firms differ as to (1) whether their practice aids for fraud risk assessment are separate or integrated with other risk assessment practice aids, (2) the timing of the fraud risk assessment, and (3) the method of assessing fraud risk. Furthermore, although all of the firms studied include all of the SAS No. 82 factors in their audit practice aids, certain other fraud risk factors identified in academic research are not included in firm practice aids.
Contoured adducted trochanteric-controlled alignment method (CAT-CAM) ; Introduction and basic principles (1985)

Since 1969, it has become increasingly evi dent that quadrilateral sockets have serious bio-mechanical problems. Even my old-timer
Opportunities and problems in modification of levels of rapeseed C<sub>18</sub> unsaturated fatty acids (1973)

Abstract Selections for different levels of C 18 fatty acids in rapeseed to date have had only limited success, due in part to the low frequency of occurrence of desired genotypes with increased linoleic and decreased linolenic acid. In the progeny of mutation experiments with seeds of the variety Oro (linolenic acid content 8–10%) two stable mutants were selected, one with 5% and the other with 20% linolenic acid in the seed oil. The level of linoleic acid in the two mutants is the same as Oro (16–20%), but the levels of oleic and linolenic acids are inversely altered. In this paper several problems associated with selecting for linoleic and linolenic acids, which became apparent during the mutation studies, are discussed. Many selections made from the mutated material were unstable, reverting to the original Oro fatty acid composition after two or three self‐pollinated generations. This fact plus environmental and maternal effects made selection difficult. However, with the use of rapid and simple analytical methods and space‐saving growing techniques, these difficulties were overcome.
Efficacy analysis of first radioiodine ablation of residual thyroid tissue in postoperative patients with thyroid cancer (2001)

Objective To study the influence of age, sex, type of surgery, pathologic type of the tumor, postoperative time to the administration and the dose of radioiodine , TSH level and the existence of radioiodine uptake beyond thyroid to first radioiodine ablat???????????????????

Key words: 
Esophageal neoplasms; Pharyngeal neoplasms; Diagnostic imaging
Rapid isothermal processing (1988)

The physics and technology of a relatively new, short-time, thermal processing technique, namely rapid isothermal processing (RIP), based on incoherent sources of light for the fabrication of semiconductor devices and circuits, are reviewed in this paper. Low-cost, minimum overall thermal budget, low-power consumption, and high throughput are some of the attractive features of RIP. The discussion of RIP, in the context of other thermal processes, history, operating principles, different types of RIP systems, various applications of RIP using single processing steps, and novel applications of RIP, including in situ processing and multistep processing, is described in detail. Current trends are in the direction of RIP-dominated silicon integrated circuit fabrication technology that can lead to the development of the most advanced three-dimensional integrated circuits suitable for applications such as parallel processing and radiation hardening. RIP is not only a superior alternative to furnace processing, but it is also the only way to perform certain crucial steps in the processing of compound semiconductor devices such as high-mobility transistors, resonant tunneling devices, and high-efficiency solar cells. Development of more accurate temperature measurement techniques and theoretical studies of heat transfer and other fundamental processes are needed. Dedicated equipment designed for a specific task coupled with in situ processing capabilities will dominate the future direction of RIP.
Gel filtration and gel permeation (1969)

C. Male and F. W. Peaker, Proc. Soc. Anal. Chem., 1969, 6, 8 DOI: 10.1039/SA9690600008
On Efficient Variance Estimators for Normal Population with known Coefficient of Variation (2009)

This paper addresses the issue of finding an optimal estimator of the normal population variance using the known coefficient of variation. In this setup there is no complete sufficient statistic for the variance, hence Rao-Blackwellization is unavailable to us. Despite this, we have been able to obtain an estimator with minimum MSE, which is more efficient than other estimators in the literature. The proposed estimator may also be the MVUE, but we have not been able to confirm this. Lastly, we examine the relative efficiencies of our estimators with respect to the usual unbiased estimator S2 by means of a numerical empirical study.
Rosiglitazone and ATRA on gastric cancer SGC7901 cell line proliferation in vitro (2010)

Objective To investigate the influence of PPARγ excitomotor RSG and ATRA on gastric cancer SGC7901 cell line proliferation in vitro and its potential mechanism study.Methods Human gastric cancer SGC7901 cell line was cultured in vitro.Experiment samples were divided to blank group,10μmol/L ATRA group, 12.5μmol/L RSG group, 25μmol/L RSG group, 10μmol/L ATRA + 25μmol/L RSG group.Proliferation inhibitory effect was determined by MTI assay.Flow cytometry was used to detect cell cycle, H.E stain was used to observed micrography alteration.Expression of PPARγ protein in gastric cancer cells were measured by immunohistochemistry.PPARγ mRNA in gastric cancer cells were measured by RT-PCR.Results ATAR at concentration 10μmol/L, RSG at 12.5 μmol/L and RSG at 25 μmol/L could inhibit the proliferation of SGC7901 cells in a dose-and time-dependent, and when both agents were combined for 72h, growth inhibition ratio was (29.73 ± 0.69) %.Flow cytometry analysis revealed a cell cycle arrest at G1 and S phase, and when both agents combined, S% was (12.87 ± 0.35 )%, cell micrography tended to be normal when both agents combined.Up-regulation of PPARγ protein and PPARγ mRNA expressions were also observed, those effects were enhanced when both agents combined, and grey scale ratio was 0.646.Conclusion The ATRA and RSG could significantly induced growth inhibition of human gastric cancer SGC7901 cell, which may be associated with cell cycle arrest and inducing differentiation, activation of PPARγ protein and PPARγ mRNA expression.Synergistic effect could be caused by the combined use of the two agents.

Key words: 
Thiazolidinediones/PD; Tretinoin/PD; Stomach neoplasms/DT/PA/ME; Cell proliferation/DE; Apoptosis/DE; PPAR gamma/ME/DE
Expediente (2019)

A Revista Aurora foi criada durante o segundo semestre de 2007 pelos estudantes do Programa de Pós-Graduação em Ciências Sociais da UNESP-Marília. Como um ambiente de aprendizagem e aperfeiçoamento de práticas editoriais a revista é gerenciada pelos discentes e supervisionada pelo professor coordenador do programa. Além disso, contamos com pareceristas externos à unidade e a editoração fornecida pelo Laboratório Editorial da UNESP (Campus Marília). A Revista Aurora tem por objetivo principal constituir-se como meio de difusão e discussão de temas clássicos e contemporâneos das Ciências Sociais, buscando sempre promoção constante do diálogo entre os núcleos dessa área do conhecimento, Antropologia, Ciência Política e Sociologia, bem como com outros campos das humanidades, como Filosofia, História, Relações Internacionais e Economia.
Adducts of 2‐aminothiophenol with acetylenic nitriles or esters and their conversion into benzothiazoles and/or 1,4‐benzothiazines (1980)

Abstract The reaction between 2‐aminothiophenol 1 and acetylenic nitriles or esters 2a‐d leads to the vinyl thio‐ethers 3a‐d. The conversion of 3 into benzothiazoles 8 and/or 1,4‐benzothiazines 9 , in boiling dimethyl sulfoxide, has been achieved. A possible pathway involving benzothiazolines 5 as key intermediates is suggested.
Pediatric cardiology: auscultation from 280 miles away. (1992)

New long-distance audio/video and data communications links among health-care facilities promise to reduce rural patients' travel time and waiting time for subspecialty consultations. To offer a satisfactory alternative to face-to-face examination, the long-distance system must meet the subspecialty's minimum criteria. For pediatric cardiology in particular, the system has to permit satisfactory cardiac auscultation. A preliminary test of remote auscultation that uses an electronic stethoscope involved two pediatric cardiologists, one listening hands-on with an acoustic stethoscope, the other listening independently at long distance with the electronic instrument. Taking the acoustic findings as the reference standard, the electronic stethoscope did not miss the one case of heart disease, correctly recommended echocardiogram follow-up in the two cases requiring it, and agreed on 80% of the murmurs' qualitative specifics. The patients' parents also indicated that the system was highly acceptable. We are following up these results with a full-scale study of the effectiveness and parental acceptance of remote auscultation.
Load forecasting techniques and methodologies: A review (2012)

Electricity demand forecasts are extremely important for energy suppliers and other participants in electric energy generation, transmission, distribution and markets. Accurate models for electric power load forecasting are essential to the operation and planning of a utility company. Load forecasts are extremely important for energy suppliers and other participants in electric energy generation, transmission, distribution and markets. This paper presents a review of electricity demand forecasting techniques. The various types of methodologies and models are included in the literature. Load forecasting can be broadly divided into three categories: short-term forecasts which are usually from one hour to one week, medium forecasts which are usually from a week to a year, and long-term forecasts which are longer than a year. Based on the various types of studies presented in these papers, the load forecasting techniques may be presented in three major groups: Traditional Forecasting technique, Modified Traditional Technique and Soft Computing Technique.
A Second Opinion on Data Flow Machines and Languages (1982)

The authors argue that due to their simplicity and strong appeal to intuition, data flow techniques attract a great deal of attention. Other alternatives, however, offer more hope for the future. 25 references.
Studies on Diastereoisomeric α-Amino Acids and Corresponding α-Hydroxy Acids. VII. Influence of β-Configuration on Enzymic Susceptibility (1956)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTStudies on Diastereoisomeric α-Amino Acids and Corresponding α-Hydroxy Acids. VII. Influence of β-Configuration on Enzymic SusceptibilityMilton Winitz, Leah Bloch-Frankenthal, Nobuo Izumiya, Sanford M. Birnbaum, Carl G. Baker, and Jesse P. GreensteinCite this: J. Am. Chem. Soc. 1956, 78, 11, 2423–2430Publication Date (Print):June 1, 1956Publication History Published online1 May 2002Published inissue 1 June 1956https://pubs.acs.org/doi/10.1021/ja01592a022https://doi.org/10.1021/ja01592a022research-articleACS PublicationsRequest reuse permissionsArticle Views856Altmetric-Citations115LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Classification of 12-Lead ECG Signals with Bi-directional LSTM Network (2018)

We propose a recurrent neural network classifier to detect pathologies in 12-lead ECG signals and train and validate the classifier with the Chinese physiological signal challenge dataset (http://www.icbeb.org/Challenge.html). The recurrent neural network consists of two bi-directional LSTM layers and can train on arbitrary-length ECG signals. Our best trained model achieved an average F1 score of 74.15% on the validation set. Keywords: ECG classification, Deep learning, RNN, Bi-directional LSTM, QRS detection.
Wind generation system - a comprehensive survey report (2008)

The rapidly increasing contribution of wind electric power generation around the world has motivated a need to develop more widely applicable methodologies for evaluating the actual benefits of adding wind turbines to traditional power generating systems. This paper mainly focuses on various recent techniques used in wind generation system in order to enhance better performance and high efficiency of the system.
A new method for observing the morphology of vesicular–arbuscular mycorrhizae (1984)

A new procedure using chlorazol black E has been developed for staining vesicular–arbuscular mycorrhizal fungi in cleared roots. In a comparative study, chlorazol black E was found to be much superior to previously used stains (acid fuchsin, trypan blue, aniline blue) for showing details of internal hyphae and particularly arbuscules. This clearing and staining procedure, combined with Nomarski interference contrast microscopy, revealed details of arbuscule structure not evident with previous techniques. Field-collected samples were also stained well by this procedure. The procedure should allow more accurate assessment of roots for colonization by vesicular–arbuscular mycorrhizal fungi.
A bivariate frequency analysis of extreme rainfall with implications for design (2007)

Analysis of extreme rainfall events has conventionally been performed by prespecifying rainfall duration as a filter to abstract annual maximum rainfall depths as the only variable for analysis. However, this univariate approach does not account for dependence between rainfall properties. To characterize extreme rainfall events, a bivariate analysis is conducted in this study using hourly precipitation data from Indiana, USA. Samples of extreme rainfall events are chosen on the basis of three different criteria: annual maximum volume (AMV), annual maximum peak intensity (AMI), and annual maximum cumulative probability (AMP) based on empirical copulas. Rainfall characteristics, such as total depth, duration, and peak intensity are analyzed using copulas to describe the dependence structures between rainfall variables and to construct their joint distribution for extreme rainfall events. Results from the derived bivariate models are compared to those from conventional univariate analysis by computing the corresponding conditional distributions. Traditional univariate analysis seems to provide reasonable estimates of rainfall depths for durations greater than 10 hours. For shorter durations, a bivariate analysis with extreme events defined on the basis of AMP is recommended. The univariate analysis combined with Huff curves grossly underestimates peak intensities, and again AMP estimates are recommended. Results of this study have implications for current hydrologic design in that they provide better estimates of design rainfall.
Targeted transgene integration overcomes variability of position effects in zebrafish (2014)

Zebrafish transgenesis is increasingly popular owing to the optical transparency and external development of embryos, which provide a scalable vertebrate model for in vivo experimentation. The ability to express transgenes in a tightly controlled spatio-temporal pattern is an important prerequisite for exploitation of zebrafish in a wide range of biomedical applications. However, conventional transgenesis methods are plagued by position effects: the regulatory environment of genomic integration sites leads to variation of expression patterns of transgenes driven by engineered cis-regulatory modules. This limitation represents a bottleneck when studying the precise function of cis-regulatory modules and their subtle variants or when various effector proteins are to be expressed for labelling and manipulation of defined sets of cells. Here, we provide evidence for the efficient elimination of variability of position effects by developing a PhiC31 integrase-based targeting method. To detect targeted integration events, a simple phenotype scoring of colour change in the lens of larvae is used. We compared PhiC31-based integration and Tol2 transgenesis in the analysis of the activity of a novel conserved enhancer from the developmentally regulated neural-specific esrrga gene. Reporter expression was highly variable among independent lines generated with Tol2, whereas all lines generated with PhiC31 into a single integration site displayed nearly identical, enhancer-specific reporter expression in brain nuclei. Moreover, we demonstrate that a modified integrase system can also be used for the detection of enhancer activity in transient transgenesis. These results demonstrate the power of the PhiC31-based transgene integration for the annotation and fine analysis of transcriptional regulatory elements and it promises to be a generally desirable tool for a range of applications, which rely on highly reproducible patterns of transgene activity in zebrafish.
Binding of different monosaccharides by lectin PA‐IIL from <i>Pseudomonas aeruginosa</i>: Thermodynamics data correlated with X‐ray structures (2006)

The lectin from Pseudomonas aeruginosa (PA-IIL) is involved in host recognition and biofilm formation. Lectin not only displays an unusually high affinity for fucose but also binds to L-fucose, L-galactose and D-arabinose that differ only by the group at position 5 of the sugar ring. Isothermal calorimetry experiments provided precise determination of affinity for the three methyl-glycosides and revealed a large enthalpy contribution. The crystal structures of the complexes of PA-IIL with L-galactose and Met-beta-D-arabinoside have been determined and compared with the PA-IIL/fucose complex described previously. A combination of the structures and thermodynamics provided clues for the role of the hydrophobic group in affinity.
Improving the Oral Bioavailability of Curcumin Using Novel Organogel-Based Nanoemulsions (2012)

Curcumin is a natural bioactive compound with many health-promoting benefits. Its low oral bioavailability limits its application in functional foods. In the present study, novel organogel-based nanoemulsions have been developed for oral delivery of curcumin and improvement of its bioavailability. Recently developed curcumin organogel was used as the oil phase in the curcumin nanoemulsion formulation. Tween 20 was selected as the emulsifier on the basis of maximum in vitro bioaccessibility of curcumin in the nanoemulsion. In vitro lipolysis profile revealed that the digestion of nanoemulsion was significantly faster and more complete than the organogel. Permeation experiments on Caco-2 cell monolayers suggested that digestion-diffusion was the major absorption mechanism for curcumin in the nanoemulsion. Furthermore, in vivo pharmacokinetics analysis on mice confirmed that the oral bioavailability of curcumin in the nanoemulsion was increased by 9-fold compared with unformulated curcumin. This novel formulation approach may also be used for oral delivery of other poorly soluble nutraceuticals with high loading capacity, which has significant impact in functional foods, dietary supplements and pharmaceutical industries.
Abrasive tip treatment for use on compressor blades (1984)

A co-spray process was used which simultaneously but separately introduces abrasive grits and metal matrix powder into the plasma stream and entraps the abrasive grits within a molten matrix to form an abrasive coating as the matrix material solidifies on test specimen surfaces. Spray trials were conducted to optimize spray parameter settings for the various matrix/grit combinations before actual spraying of the test specimens. Rub, erosion, and bond adhesion tests were conducted on the coated specimens in the as-sprayed condition as well as on coated specimens that were aged for 100 hours at a temperature of 866K (1100 F). Microscopic examinations were performed to determine the coating abrasive-particle content, the size and shape of the adhesive particles in the coating, and the extent of compositional or morphological changes resulting from the aging process. A nickel chromium/aluminum composite with No. 150 size (0.002 to 0.005 inch) silicon carbide grits was selected as the best matrix/abrasive combination of the candidates surveyed for coating compressor blade tips.