gebhart/patrepeval huggingface dataset:
Vascular Endothelial Growth Factor mRNA in Pericytes Is Upregulated by Phorbol Myristate Acetate (1998)

Increased microvascular permeability, which occurs in conditions such as the adult respiratory distress syndrome and diabetes mellitus, is related to physicochemical alterations in the microvascular barrier. We postulate that, in part, capillary pericytes affect microvascular permeability via production of a vasoactive cytokine, viz, vascular endothelial growth factor (VEGF), also known as vascular permeability factor. The goal of the present study was to evaluate the effects of phorbol myristate acetate (PMA), a substance known to produce nonhydrostatic pulmonary edema in intact animals, on VEGF gene expression in pericyte cultures. Microvascular pericytes were isolated from bovine retinas using magnetic microspheres coated with 3G5 monoclonal antibody. Pericyte identity was confirmed both morphologically and by immunostaining for alpha-smooth muscle actin and 3G5 ganglioside. The cultured pericytes were stimulated with N(omega)-nitro-L-arginine methyl ester (L-NAME, 1 x 10(-4) mmol/L), angiotensin II (1 x 10(-6) mmol/L), and PMA (5 x 10(-8) mmol/L), selected because of their ability to upregulate VEGF mRNA expressions in other cell types. Northern blot analysis was performed using [32P]dCTP labeled human VEGF cDNA (Genentech). Lane-loading differences were normalized using mouse GAPDH control cDNA probe. VEGF mRNA expression was upregulated by PMA (10(-9) to 10(-6) mol/L) in a dose-dependent manner, whereas neither L-NAME nor angiotensin II affected VEGF mRNA expression in pericytes. These results support the hypothesis that pericytes increase permeability of the endothelial barrier through increased VEGF production.
Performance of integrated services (voice/data) CSMA/CD networks (1985)

ABSl'RA(X We consider a voice/data integrated local area communication system. Due to the high suitability of CSMAKD protocols for data communication and the existence of real time voice delay constraints we consider a hybrid TDMKSMAKD protocol. This model fundamentally differs from the very well documented voice/data integrated systems in point to point networks in which both voice and data users are assigned fixed duration time slots for transmission. The TDPKSMAKD integrated system performance is analysed and basic performance tradeoffs in the system design are manifested.
Une tumeur intra-canalaire papillaire et mucineuse… des voies biliaires (2001)

Les papillomatoses des voies biliaires sont des tumeurs rares dont le principal risque est celui de la récidive et de la transformation maligne. Nous rapportons l’observation d’une femme présentant une forme de papillomatose biliaire inhabituelle sous la forme d’une tumeur biliaire productrice de mucines et s’apparentant aux tumeurs intra-canalaires papillaires et mucineuses pancréatiques.
Flow patterns and stresses on the wall in a two‐dimensional flat‐bottomed bin (2003)

Abstract The flow patterns and stresses on the wall in a two‐dimensional flat‐bottomed bin with centric and eccentric discharges were investigated. The flow pattern histories of granular solids in the bin were recorded using a digital camcorder. A pressure gauge for simultaneously measuring the normal and shear stresses of granular solids was used. During filling with the granular material, the variations in stresses acting on the side walls with time were observed. The dynamic wall stresses were obtained during the centric and eccentric discharges. In addition, using Mohr's stress circle, an analysis of the stress state at the bin side‐wall was determined. The normal and shear stress fluctuation ranges predicted by Mohr's stress circle were close to the experimental results. The effect of the discharge slot position upon the wall stress was also demonstrated. Employing the results obtained using stress measurements and image processing, the pressure pulsation phenomena in a bin may be understood further.
Safety and pharmacokinetics of vitamin A therapy for infants with respiratory syncytial virus infections (1995)

Infants with respiratory syncytial virus infection have low serum vitamin A levels. We treated 21 respiratory syncytial virus-infected children with 12,500 to 25,000 IU of oral vitamin A. Vitamin A levels were normalized at 6 h, and none of the children experienced vitamin A toxicity or exacerbation of respiratory illness. Vitamin A treatment of previously healthy respiratory syncytial virus-infected infants at these doses is safe and well tolerated.
ADA, the Programming Language of Choice for the UPMSat-2 Satellite (2015)

The proper selection of development mechanisms and
tools is essential for the final success of any engineering project. This is also true when it comes to software development. Furthermore, when the system shows very specific and hard to meet requirements, as it happens for high-integrity real-time systems, the appropriate selection is crucial. For this kind of systems, Ada has proven to be a successful companion, and satellites are not an exception. The paper presents the reasons behind the selection of Ada for the UPMSat-2 development, along with the experience and examples on its usage.
Hydrogen Bonding Interactions Between Ions: A Powerful Tool in Molecular Crystal Engineering (2004)

Abstract For Abstract see ChemInform Abstract in Full Text.
ChemInform Abstract: Synthesis of Monolithic Uranium Hydride and Uranium Deuteride. (1990)

Abstract UHx (UDx) crystals are grown from the melt at temp. above 1065 °C under 125 MPa H 2 (D2) pressure.
The dermatologist's guide to hereditary syndromes with renal tumors. (2008)

Patients with hereditary syndromes with renal tumors initially may present to the dermatologist. It is essential that dermatologists recognize these syndromes because the early diagnosis of renal cancer may prove to be lifesaving. The 4 hereditary syndromes with cutaneous manifestations are von Hippel-Lindau (VHL) syndrome, Birt-Hogg-Dube (BHD) syndrome, tuberous sclerosis (TS), and hereditary leiomyoma renal cell carcinoma (HLRCC) syndrome. This article reviews these disorders, emphasizing their cutaneous features and renal manifestations.
and In Vitro Enhancement of the Residual a-L-lduronidase Activities (1988)

The enzymatic and immunologic properties of the defective residual a-L-iduronidase activities were investigated in fibroblast extracts from the three subtypes of mucopolysaccharidosis type I, Hurler (MPS IH), Scheie (MPS IS), and HurlerScheie (MPS IH-S) diseases. Using 4-methylumbelliferyl-aL-iduronide (4MU-a-Id), the activities in fibroblast extracts from all three subtypes were less than 0.1% of normal. Rocket immunoelectrophoresis with monospecific rabbit anti-human a-L-iduronidase polyclonal antibodies, as well as immunoblots using a monoclonal antibody, revealed the presence of crossreactive immunologic material (CRIM) in extracts prepared from each subtype. When the samples were equalized for 8hexosaminidaseA activity, 38-105% ofnormal enzyme protein was detected. The sequential addition of cystamine, MgCl2 and pyridoxal phosphate increased the residual 4MU-a-Id activities in subtype extracts up to about 35% ofnormal mean fibroblast activity. Cystamine, MgC2 or pyridoxal phosphate alone enhanced the residual activities two- to fourfold, whereas the sequential addition of all three compounds was required for maximal effect. Of the six B6 vitamers evaluated, only the negatively charged forms, pyridoxamine (PLN), pyridoxamine phosphate (PNP), and pyridoxal phosphate (PLP), stimulated the residual activities. The addition ofdermatan sulfate or heparan sulfate to the subtype extracts, followed by treatment with the effector compounds, similarly inhibited both the normal and enhanced MPS I activities. Heat inactivation experiments confirmed the fact that the mutant iduronidase activity was reconstituted and that the observed increase in enzymatic activity was not an artifact of the fluorogenic assay. These results suggest that the presence of certain thiol reducing agents, divalent cations and negatively charged B6 vitamers can alter the conformation of the mutant ac-L-iduronidase in vitro such that the hydrolysis of 4MU-a-Id is enhanced into the heterozygote range.
[Association between GSK3β polymorphisms and the smoking habits in young Japanese]. (2015)

Schizophrenia and bipolar disorder show high comorbidity with smoking dependence. Several previous studies reported that glycogen synthase kinase 3β (GSK3β), which is widely expressed in the brain including the dopamine projection areas such as the amygdala, nucleus accumbens and hippocampus, may play a role in neuropsychiatric disorders and dopamine- and serotonin-mediated behavior. In this study, we have analyzed the association of three single nucleotide polymorphisms (SNPs) within GSK3β gene (rs3755557, rs334558, rs6438552) with the smoking habits and age at smoking initiation in a sample of 384 young adult Japanese, which included 172 smokers and 212 non-smokers. As a result, rs334558 was significantly associated with smoking habits in genotype frequency and allelic frequency (P < 0.05). Furthermore, higher haplotype 3 (T-T-T) and haplotype 5 (A-T-C) frequencies were observed in non-smokers than smokers (P < 0.05). Three functional polymorphisms examined in this study reportedly increase transcriptional activity when they have a high-activation allele such as the A allele of -1727A/T (rs3755557), the T allele of -50T/C (rs334558) or T allele of -157T/C (rs6438552). Thus, it was suggested in this study that changes in GSK3β activity may have an impact on smoking habits.
High Tc superconductors : proceedings of Symposium A on High Temperature Superconductors--Preparation and Properties of the 1988 E-MRS Fall Conference, Strasbourg, France, 8-10 November 1988 (1989)

Contents: Vol. I. 1. General Theory. Unconventional superconducting properties of the High T c oxides (G. Deutscher). Understanding high temperature superconducting oxides (B.K. Chakraverty et al.). Raman scattering as an analytical tool for high T c superconductors (C. Thomsen et al.). 2. Structure, New Materials and Substitution. Structures and microstructures in the bismuth and thallium superconductors (M. Hervieu et al.). Electron microscopic studies of high T c superconductors (S. Amelinckx et al.). Structure and conductivity of copper oxide based compounds (D.M. de Leeuw). Order-disorder and superconductivity in Tl-Ba-Cu-O and lead-substituted Bi-Sr-Ca-Cu-O compounds (P. Bordet et al.). A homologous series based on YBaCuO, YBa 16 Y 2 Cu 24 C 56-m (0<m<8, m even) (M.A. Alario-Franco et al.). Two new bulk superconducting phases in the Y-Ba-Cu-O system: Ba 2 Cu 3.5 O 7-e (T c =40K) and YBa 2 Cu 4 O 8+x (T c =80 K) (J. Karpinski et al.). Characterization of bulk superconducting high-temperature ceramics by very low field a.c. initial susceptibility (B. Loegel et al.). High-pressure phase diagrams (1 . 3000 bar oxygen) of the (Y-Ba-Cu-O)-O 2 systems (J. Karpinski et al.). Reproducible growth of large free crystals of YBa 2 Cu 3 O 7-x (W. Sadowski, H.J. Scheel). Crystal fibers of Bi-Sr-Ca-Cu-O materials grown by the laser floating zone method (G.F. de la Fuente et al.). High T c phase stabilization in Bi-Ca-Sr-Cu-O systems by lead doping (N. Brnicevic et al.). Preparation of superconductors of the BiSrCaCuO system by glass crystallization (A.P. Concalves et al.). Vol. II. 3. Physical Properties. The breaking torque concept in a sintered LaSrCuO sample (L. Fruchter et al.). Critical currents and magnetic relaxation of epitaxial YBa 2 Cu 8 O 7-h films (R. Griessen et al.). 4. Materials, Single Crystals, Phase Diagrams. Crystal growth of oxide superconductors (H.J. Scheel). 5. Thin Films. Direct production and properties of sputtered epitaxial YBa 2 Cu 3 O 7 thin and ultrathin films on (100) and (110) SrTiO 3 (H. Schubert et al.). 6. Applications. The development of SQUID magnetometers using bulk ceramic superconductors (C.E. Gough et al.). Author Index. Subject Index.
ChemInform Abstract: Enhancement Effect of Gold and Silver on Nitric Oxide Decomposition over Pd/Al2O3 Catalysts. (1995)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
The Magellanic irregular galaxy NGC 4214 - Star formation and the interstellar medium (1988)

Near- and far-infrared continuum and J = 1 - 0 CO emission-line observations of the Magellanic irregular galaxy NGC 4214 are presented and discussed. We find that the 160 micron emission is concentrated toward the visually brighter central parts of the galaxy, although there appears to be some low-level emission that extends outward from this core. We observed the J = 1 - 0 CO line emission in order to estimate the mass of starforming molecular material in the object. Only if we use a "nonstandard" conversion between CO line strength and H_2_ mass does the derived molecular mass agree with that estimated from the cool dust emission. In agreement with earlier results, we believe that the CO line emission underestimates the H_2_ mass as a result of lower metallicity in the galaxy. The total current star-formation rate is typical for this type of galaxy, 0.5-1 M_sun_ yr^-1^. Based upon analysis of the blue flux, this rate has been maintained to within about a factor of 4 for about a billion years. We do not believe that we are able to estimate the constancy of star formation to better than this factor. The star-formation rate in the center of the galaxy, averaged over a Hubble time, is apparently much lower than the current rate. We calculate that the average efficiency of star formation is about 1.5%, comparable to values found for other star-forming galaxies such as late-type spirals and the Milky Way.
Structural properties and transport characteristics of pseudomorphic Ga<i>x</i>In1−<i>x</i>As/Al<i>y</i>In1−<i>y</i>As modulation-doped heterostructures grown by molecular-beam epitaxy (1992)

Non-lattice-matched GaxIn1−xAs/AlyIn1−yAs modulation-doped heterostructures grown on (100) InP by molecular-beam epitaxy suitable for application in field-effect transistors have been studied. A computer simulation of the x-ray diffraction pattern proves to be necessary to obtain precise information about the structural parameters of the samples. The high crystal quality of our samples is demonstrated by the excellent agreement between experimental and simulated x-ray-diffraction curves. The transport characteristics of Ga0.38In0.62As/AlyIn1−yAs heterostructures including the evolution of the mobility and of the two-dimensional electron-gas density with temperature and structural parameters are discussed in relation with the relevant scattering mechanisms. The use of a thin spacer layer makes it possible to obtain very high conductivities. Both x-ray and transport measurements show that the strained GaxIn1−xAs layers are pseudomorphic well above the critical thickness calculated with the mechanical equilibrium model. The highest mobilities (13 100 and 103 000 cm2 V−1 s−1 at 300 and 4 K, respectively), obtained with a sheet carrier density of 1.7×1012 cm−2, are measured on a Ga0.38In0.62As/Al0.51In0.49As heterostructure. They are among the best values reported so far for similar structures.
Design studies for advanced thermal batteries (2003)

Two advanced thermal battery designs are reviewed. A 28 V thermal battery was encased in titanium hardware and developed for pulse loading over a 300 s lifetime. The use of titanium or its alloys, having reduced weight, greater strength, and favorable thermal properties, yielded extended thermal lifetimes resulting in substantial specific energy gains. A 50 g thermal battery incorporating a titanium alloy case for use in a high acceleration environment is also presented. Advanced concepts in the enclosure design were employed to reduce stress and titanium was used as the case material for low weight and high strength.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Using Deep Learning to Identify Patients with Cognitive Impairment in\n Electronic Health Records (2021)

Dementia is a neurodegenerative disorder that causes cognitive decline and\naffects more than 50 million people worldwide. Dementia is under-diagnosed by\nhealthcare professionals - only one in four people who suffer from dementia are\ndiagnosed. Even when a diagnosis is made, it may not be entered as a structured\nInternational Classification of Diseases (ICD) diagnosis code in a patient's\ncharts. Information relevant to cognitive impairment (CI) is often found within\nelectronic health records (EHR), but manual review of clinician notes by\nexperts is both time consuming and often prone to errors. Automated mining of\nthese notes presents an opportunity to label patients with cognitive impairment\nin EHR data. We developed natural language processing (NLP) tools to identify\npatients with cognitive impairment and demonstrate that linguistic context\nenhances performance for the cognitive impairment classification task. We\nfine-tuned our attention based deep learning model, which can learn from\ncomplex language structures, and substantially improved accuracy (0.93)\nrelative to a baseline NLP model (0.84). Further, we show that deep learning\nNLP can successfully identify dementia patients without dementia-related ICD\ncodes or medications.\n
Soil moisture sensor with built-in fault-detection capabilities (2002)

A soil moisture sensor (SMS) was built around a RISC-like microcontroller and common peripherals to perform data acquisition, signal processing, configuration, fault-detection and data communication with control/management systems. The SMS employs capacitance and heat-pulse techniques to determine the soil water content. The sensor uses the capacitance technique as the main method while the heat-pulse readings, acquired at a lower rate, are used for calibration and fault detection purposes. The temperature sensors and the heater were assembled in a four-needle probe. Several experiments were conducted for different types of soil. The results showed that this sensor could be applied in an effective way to measure the soil water content. Several tests are being performed to conclude about the sensor dependence with soil temperature and chemical composition as well about its long-term stability.
Investigation of vacuum insulator surface dielectric strength with nanosecond pulses (2004)

The maximum vacuum insulator surface dielectric strength determines the acceleration electric field gradient possible in a short pulse accelerator. Previous work has indicated that higher electric field strengths along the insulator-vacuum interface might be obtained as the pulse duration is decreased S. Sampayan et al. (1995). In this work, a 250 kV, single ns wide impulse source was applied to small diameter, segmented insulators samples in a vacuum to evaluate the multilayer surface dielectric strength of the sample construction. Resonances in the low inductance test geometry were used to obtain unipolar, pulsed electric fields in excess of 100 MV/m on the insulator surface. The sample construction, experimental arrangement and experimental results are presented for the initial data in this work. Modeling of the multilayer structure is discussed and methods of improving insulator surface dielectric strength in a vacuum are proposed.
ChemInform Abstract: Synthesis and Biological Properties of New Benz(h)isoquinoline Derivatives. (1994)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Distributed massive MIMO for estimation of a correlated source vector in sensor networks (2017)

Distributed massive MIMO (DM-MIMO) systems are a key enabler to improve the energy efficiency (EE) in future wireless networks. Thereby, herein this architecture is considered for the estimation of a correlated source vector in wireless sensor networks (WSN), where each sensor node amplifies and forwards its observation through a coherent Multiple Access Channel (MAC) channel. Namely, the fusion centre (FC) consists of a large number of distributed single antenna access points (AP) connected through a backhaul network to a central processing unit (CPU), where a Linear Minimum Mean Square Error (LMMSE) estimation is computed. Within this setting the exact and an approximated MSE, obtained by the LMMSE estimation, are derived. Bearing in mind these results, we address the design of the optimal power allocation, at each sensor node, to minimize the total transmitted power subject to an MSE estimation constraint. The approximation of the MSE paves the way to cast the optimal allocation problem as a Semidefinite Programming Problem (SDP). Finally, the numerical simulations show that our system permits to reduce significantly the total transmitted power compared to related work architectures proposing a massive MIMO system where all the antennas are collocated at the FC.
Mesoscopic Epifluorescence Tomography: Reconstruction of superficial and deep fluorescence in highly-scattering media (2010)

Mesoscopic Epifluorescence Tomography (MEFT) is a technique derived from Laminar Optical Tomography (LOT), determining fluorescence biodistribution by tomographic means in reflectance geometry. A pencil beam is scanned over the region of interest to excite fluorophores hidden within the tissue, while a CCD camera acquires images of reflected fluorescence emissions. This configuration is advantageous whenever transillumination of the specimen is not feasible, e.g., in the presence of skin chambers or when using wavelengths in the visible range where absorption is high. We present simulation and phantom studies recovering deep GFP-like fluorescence in highly scattering and strongly absorbing media with a penetration depth up to 10mm.
EE-CAN: Energy efficient clustering in aerial networks (2017)

Aerial networks based on Low Altitude Platforms (LAP) provides an excellent method to rapidly deploy flexible communications infrastructure during large-scale emergency and public events. In such situations, it is of utmost importance to extend the lifetime of the battery operated hand-held devices serving on the ground. In this paper, we propose a novel clustering technique to improve the energy efficiency of the terrestrial nodes served by the aerial base-station under uncertain channel conditions on the ground. The proposed technique is analysed by means of simulations and the results are compared with well-known clustering algorithms. The results show that the proposed clustering mechanism significantly improves the energy efficiency of the terrestrial nodes under certain conditions.
Influence of Processing Technological Parameters of Carbon Perform on Microstructure and Property of Reaction-Bonded SiC (2004)

The effect of the processing technological parameters on the microstructure and property of reaction-bonded SiC is studied.The results show that these parameters,i.e.carbon content,carbon and silicon carbide partical size and the shaped press value are critical in determining the final microstructure and property,because they have influences on the matching of green porosity and carbon content.The optimal structure and property of specimens can be obtained by manufacturing from 90% SiC of 42μm with 10% carbon of 42μm,and being pressed at 140 MPa.