gebhart/patrepeval huggingface dataset:
Chiral discrimination in the monolayer packing of hexadecylthiophospho-2-phenylglycinol with two chiral centers in the polar head group (1989)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTChiral discrimination in the monolayer packing of hexadecylthiophospho-2-phenylglycinol with two chiral centers in the polar head groupMaya Dvolaitzky and Marie Alice Guedeau-BoudevilleCite this: Langmuir 1989, 5, 5, 1200–1205Publication Date (Print):September 1, 1989Publication History Published online1 May 2002Published inissue 1 September 1989https://pubs.acs.org/doi/10.1021/la00089a013https://doi.org/10.1021/la00089a013research-articleACS PublicationsRequest reuse permissionsArticle Views88Altmetric-Citations10LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Viewing molecules with scanning tunneling microscopy and atomic force microscopy (1990)

Two new microscopic techniques make it possible to obtain images of biologically interesting molecules directly in air, vacuum, or under water. Scanning tunneling microscopy and atomic force microscopy both have the capacity to visualize atoms on the surface of rigid structures and provide details of molecular structure for lipids, proteins, carbohydrates, and nucleic acids. In addition to providing visualizations of individual molecules, these scanning probe techniques allow direct imaging of complexes between molecules or between molecules and higher-order subcellular structures such as membranes and cytoskeletal components. Both microscopes can be operated under a variety of ambient conditions ranging from high vacuum to above atmospheric pressure. Specimens need not be dry; both techniques have been used to image molecules in aqueous media under nearly physiological conditions. It is proposed that as these techniques mature they will allow direct observation of many molecular interactions under physiological conditions or even in vivo while they are occurring within the cell.
The optimization of L‐lysine fermentation and a mass transfer model (1984)

Abstract The efficiency of L‐lysine biosynthesis is essentially determined by the power input and aeration ratio in the stirred fermenter. A mass transfer model was developed by means of the results of lysine fermentations in four geometrically similar fermenters with working volumes of 10 1, 50 1, 100 1 and 2500 1 which allows the optimization of lysine fermentation from the energetical point of view. The usefullness of this k L a ‐model is demonstrated with an example where the power input for an unknown fermenter is calculated.
804 Tastes: Evidence on Preferences, Randomness, and Value from Double-Blind Wine Tastings (2012)

Abstract Results for a total of 804 double-blind tastes by experienced tasters during nine tasting events are reported. T -test results reject the hypothesis that flight-position bias affects results. The distribution of ranks for a wine is a mixture distribution, and tests concerning the variance of that mixture distribution do not isolate the variance due to the randomness mixture component alone. T -statistics for the mean ranks of high- and low-ranking wines are over several standard deviations from a random expectation. T -tests show that the statistical significance of the difference between wine ranks is positively related to the difference in their mean ranks. At a 95% level of significance, the difference in ranks between the first- and second-place wines appears to be significant in 33% of tastings. At 95%, the difference in ranks between the first- and last-place wines appears to be significant in 100% of tastings. Monte Carlo simulation shows that much of those differences could be illusory and due to ranking procedures that lead to Type I errors. While the mean correlation coefficient between price per bottle and mean preference is a weakly positive 0.23, this may not indicate an inefficient market. (JEL Classifications: A10, C00, C12, D12)
Comparative study of PFAS treatment by UV, UV/ozone, and fractionations with air and ozonated air (2019)

Conducted using multifunctional equipment, this comparative study showed 95% PFAS removal achieved by ozonated air fractionation.
Time Scaling Property on Edge Routers (2006)

Accurate traffic model is crucial for network applications. Delay and its second measures, i.e. jitter, represent network activity and compose the function to assess the traffic model. In this paper, we show time scaling analysis for jitter on different type of edge routers based on wavelet scaling analysis. After collecting the actual data using our implemented path based active measurement method, following results are extracted. Firstly, the edge router from LAN to WAN diverse average energies to different values. Secondly, the property of average energy propagates through the path even if local return process operates heavily on the middle of the path. Thirdly, the exchanging point between providers raises average energy caused not only by local return element but also by forwarding and backwarding elements. Finally, bandwidth restriction between Japan and the U.S. slightly increases jitter fluctuations
A clinical trial of fibroblast transplantation for the treatment of mucopolysaccharidoses (1982)

This paper reports the clinical and biochemical results in six patients with Hurler disease (Mucopolysaccharidosis IH; McKusick 25280), two patients with Hunter disease (Mucopolysaccharidosis II; McKusick 25285) and one patient with Sanfilippo B disease (Mucopolysaccharidosis IIIB; McKusick 25292) who were treated by fibroblast transplantation. Except for one patient who died for a coincidental reason, the patients have been studied for between 2.5 and 4.5 years. The clinical course of the disease was not materially altered. There was no evidence that the patients had developed immune responses against the transplanted fibroblasts. Transplantation did not produce measurable levels of either alpha-L-iduronidase (EC 3.2.1.76) in the leukocytes from patients with Hurler disease or of N-acetyl-alpha-D-glucosaminidase (EC 3.2.1.50) in the plasma of the patients with Sanfilippo B disease. Under the conditions used for the assay, leukocytes from the patients with Hunter disease had detectable levels of residual alpha-L-idurono-2-sulphate sulphatase activity which were increased after the transplants, although these changes were of inconstant size and their time course was not consistently related to the transplantations. Cytogenetic studies in cases where the donor was of the opposite sex detected only cells of the recipient's sex among the fibroblasts grown from biopsies of the transplantation sites. The technique used would have detected a donor to recipient cell ratio of 1:100. We found no consistent long-term trends in the excretion patterns of glycosaminoglycans and oligosaccharides from either a quantitative or qualitative point of view which could be specifically related to the transplantation. The combined administration of immunosuppressive doses of prednisolone and azathioprine was associated with an increased excretion of the lower molecular weight glycosaminoglycans. We conclude that fibroblast transplantation is not therapeutically useful in the diseases studied.
Optimum design of two cascaded peaking current sources (1981)

Transfer characteristics and the temperature coefficient of output current are deduced for two cascaded peaking current sources. Optimum design equations are derived.
해양 환경하 콘크리트 교량의 탄산화 내구성능 평가 인자 도출을 위한 현장조사 연구 (2015)

In this study, on the basis of the results of the field survey and the theoretical consideration for Korean Standard Specification for concrete durability and maintenance, the following conclusions are derived. From the survey, the prediction equation of carbonation depth for the southwest region in Korea is experimentally proposed, y _{p=5.865 sqrt {t}}, which predicts about 60mm of the carbonation depth for the concrete structures of 100 years, a 1st class of target endurance period, under a combined deterioration environment like a marine environment. Considering that the marginal value for a carbonation depth limitation under very severely marine environment is 25mm, in accordance with the Specification, it is found that the predicting carbonation depth for the concrete cover depths, 100mm and 60mm are 63mm and 29.4mm, respectively. In conclusion, according to the equation and the Specification, it is strongly required that the reinforced concrete structures with the cover depth under 100mm have to make a protection from combined deterioration factors by any methods like a surface coating, an increment of cover depth or an application of a special concrete.
Frequency Dependence of the Coercivity of Soft Magnetic Materials (2012)

On different soft magnetic materials (such as pure Fe, Ni, Fe3% Si, Fe6.5% Si) the frequency dependence (from 0.5 to 50 Hz) of the hysteresis loop was measured on ring shaped samples. The samples were plastically deformed at different temperatures using the so-called high pressure torsion (HPT) method. From these data the frequency dependence of the coercivity for all samples can be deduced. A simple model based on eddy currents in the material is developed in order to describe the change of the coercivity with frequency. The most important parameter here is the relative permeability, which can be estimated from this model. The relative permeability was additionally determined from a plot of dB/dt versus the external field, which was in this case a triangular shaped H(t). The model parameters are compared and discussed. The internal stress due to the HPT treatment was estimated directly from the coercivity.
Expression regulation of the yeast <i>PDR5</i> ATP‐binding cassette (ABC) transporter suggests a role in cellular detoxification during the exponential growth phase (2004)

The yeast ATP-binding cassette transporter Pdr5p mediates pleiotropic drug resistance (PDR) by effluxing a variety of xenobiotics. Immunoblotting demonstrates that Pdr5p levels are high in the logarithmic growth phase, while its levels decrease sharply when cells exit exponential growth. Here, we show that PDR5 promoter activity is dramatically reduced when cells stop growing due to a limitation of glucose or nitrogen or when they approach stationary phase. Interestingly, Pdr3p, a major transcriptional regulator of PDR5, shows the same regulatory pattern. Feeding glucose to starved cells rapidly re-induces both PDR5 and PDR3 transcription. Importantly, diminished Pdr5p levels, as present after starvation, are rapidly restored in response to xenobiotic challenges that activate the transcription factors Pdr1p and Pdr3p. Our data indicate a role for yeast Pdr5p in cellular detoxification during exponential growth.
Nanowire-based frequency-selective capacitive photodetector for resonant detection of infrared radiation at room temperature (2014)

Characteristics of a capacitive infrared photodetector that works at room temperature by registering a change in capacitance upon illumination are reported. If used in an ideal resonant inductor-resistor-capacitor circuit, it can exhibit zero dark current, zero standby power dissipation, infinite detectivity, and infinite light-to-dark contrast ratio. It is also made frequency-selective by employing semiconductor nanowires that selectively absorb photons of energies close to the nanowire's bandgap. Based on measured parameters, the normalized detectivity is estimated to be ∼3 × 107 Jones for 1.6 μm IR wavelength at room temperature.
Aripiprazol (Abilify®) in der Schizophreniebehandlung (2005)

Seit kurzem ist Aripiprazol zur Behandlung schizophrener Störungen zugelassen. Mit Blick auf seine agonistisch-antagonistischen Eigenschaften an zentralen Dopamin (D2)-Rezeptoren kann es als Vertreter einer neuen Generation von Antipsychotika, den sog. Stabilisatoren des Dopaminsystems, bezeichnet werden. In der Mini-Review werden neurobiologische Aspekte, klinische Wirksamkeit, Pharmakokinetik und Interaktionen sowie unerwünschte Wirkungen knapp beleuchtet.
Floating In Situ Gel based on Alginate as Carrier for Stomach-Specific Drug Delivery of Famotidine (2010)

Alginate based floating in situ gelling systems of famotidine (FIGF) were prepared by dissolving varying concentrations of alginate in deionized water containing sodium citrate, to which varying concentrations of drug and calcium chloride was added and dissolved by stirring. Results of preliminary trials indicate that concentrations of sodium alginate, calcium chloride and sodium citrate affected the characteristics of in situ gel. A 32 full factorial design was employed to study the effect of independent variables, concentration of sodium alginate (X1) and concentration of calcium chloride (X2) on dependent variables, i.e. viscosity, drug content, drug release at 4 hrs (Q50) and drug release at 8 hrs (Q80). A sustained drug release was obtained for more than 8 hrs. In vivo testing of FIGF to albino Wistar rats demonstrated significant anti-ulcer effect of famotidine.
Multi-channel wireless sensor networks : protocols, design and evaluation (2009)

Pervasive systems, which are described as networked embedded systems integrated with everyday environments, are considered to have the potential to change our daily lives by creating smart surroundings and by their ubiquity, just as the Internet. In the last decade, "Wireless Sensor Networks" have appeared as one of the real-world examples of pervasive systems by combining automated sensing, embedded computing and wireless networking into tiny embedded devices.
Recovery rates in generalized anxiety disorder following psychological therapy: an analysis of clinically significant change in the STAI-T across outcome studies since 1990 (1999)

Jacobson methodology, in distinguishing between improvement and recovery on a standardized measure of general vulnerability to anxiety, provides a stringent but clinically more meaningful evaluation of the efficacy of psychological therapies with GAD than has been available hitherto. Systematic focus on either excessive worry or physiological arousal gives worthwhile results.
The Trypanocidal Activity of Naphthoquinones: A Review (2009)

Naphthoquinones are compounds present in several families of higher plants. Their molecular structures confer redox properties, and they are involved in multiple biological oxidative processes. In folk medicine, especially among Indian populations, plants containing naphthoquinones have been employed for the treatment of various diseases. The biological redox cycle of quinones can be initiated by one electron reduction leading to the formation of semiquinones, unstable intermediates that react rapidly with molecular oxygen, generating free radicals. Alternatively, the reduction by two electrons, mediated by DT-diphorase, leads to the formation of hydroquinone. Lapachol, alpha-lapachone and beta-lapachone, which are isolated from the heartwood of trees of the Bignoniaceae family, are examples of bioactive naphthoquinones. In this review, we will discuss studies investigating the activity of these natural products and their derivatives in the context of the search for alternative drugs for Chagas disease, caused by Trypanosoma cruzi, a neglected illness that is endemic in Latin America.
Automatic pump Patent (1968)

Automatically reciprocating, high pressure pump for use in spacecraft cryogenic propellants
Synthesis of New Quinoline Derivatives as Inhibitors of Human Tumor Cells Growth (2010)

A series of new 8-[(2H-tetrazol-5-yl)methoxy]quinoline derivatives, their sugar hydrazones, and their N-glycoside derivatives were synthesized. Furthermore, the 1,2,4-triazole-3-one derivatives 3 and 4 were synthesized from the amidrazone derivative 2. Some of the newly prepared compounds demonstrated inhibitory effects on the growth of MCF-7 human breast cancer cells as compared with the activity of the commonly used anticancer drug, cisplatin. The results of antitumor evaluation revealed that compounds 2-5, 8b, and 12 inhibited the growth of cancer cells through their effect as free-radical regulators by increasing the activity of superoxide dismutase and depletion of intracellular levels of reduced glutathione, catalase and glutathione peroxidase activities, accompanied with a high production of hydrogen peroxide, nitric oxide, and other free radicals causing the killing of tumor cells. The results suggested that the prepared compounds possess significant anticancer activity comparable to cisplatin and the antitumor activity of these prepared compounds was accompanied with a reduction in the levels of protein and nucleic acids.
Progress in the diagnosis and treatment of the urgency urinary incontinence in elder females (2016)

Urinary incontinence (UI) is common in elder women. Urgency urinary incontinence(UUI) is the common type of UI. Millions of women worldwide suffer from UUI nowadays, which seriously affects the health and life quality of female patients. With the aging of population in our country, the incidence of UUI increases. With the needs of quality of life rising gradually, the diagnosis and treatment of the disease are also increasingly valued and keeping step forward. However, there is still lack of one single and effective treatment for the disease, so that comprehensive treatments are used commonly. Here we make a review about the recent progress in diagnosis and treatment about UUI in elder women.


Key words: 
Urinary Incontinence, Urge; Diagnosis; Therapeutic uses; Aged; Women
Analog-input digital phase-locked loops for precise frequency and phase demodulation (1995)

Most conventional analog-input digital phase-locked loops (ADPLL's) suffer from the effect of in-loop quantization and from nonlinear behavior caused by the approximations inherent in practical digitally controlled oscillators (DCO's). The resulting errors limit the accuracy of ADPLL-based frequency demodulation and usually make ADPLL-based phase demodulation impractical because of severe phase-drift problems. This paper presents a new class of ADPLL's that are insensitive to the deleterious effects of quantization, and do not exhibit nonlinear behavior when implemented with practical DCO's. The ADPLL's are well suited to applications requiring precise frequency demodulation, and can also be used for phase demodulation because their quantization error is well behaved even after discrete-time integration. The paper establishes an analogy between the ADPLL's and delta-sigma modulators, and applies existing delta-sigma modulator results to predict the frequency and phase demodulation accuracy of the ADPLL's. A mechanization of the general architecture consisting of easily implemented components such as analog integrators, digital flip-flops, and digital counters is then presented and analyzed.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
An overview of existing CD‐ROM standards (1996)

Highlights the need for standards for the CD‐ROM industry to ensure compatibility and to increase the economies of scale to attract wider market accessibility. CD‐ROM, as a unique publishing medium, has standards mainly at three levels: the physical level, concerning the physical and recording characteristics of the medium; the logical level, concerning the nature of files, directories, volume descriptors, etc.; and the application level, concerning retrieval software, graphics, compression, encryption, etc. Concludes that CD‐ROM technology brings database services within the reach of information centres, especially in developing countries. Positive trends towards standardization in this technology possibly help to reduce the technical hurdles.
PROFILING RADIOACTIVE SNOW GAGE. (1970)

This study was undertaken to determine if commonly used orthotics (Palumbo "Dynamic Patellar Brace" [DynOrthotics, Vienna, Virginia] and the Cho-Pat Knee Strap [Cho-Pat Inc, Hainesport, New Jersey]) are helpful in the management of anterior knee pain in an active population who are unable to significantly modify their activity due to basic training requirements. In a prospective, randomized study, 59 Air Force Academy basic cadets who presented with anterior knee pain during the initial phases of basic cadet training, were placed into one of the three treatment groups. Group A was assigned no brace, group B was issued a Palumbo "Dynamic Patellar Brace," and group C was issued a Cho-Pat Knee Strap. All patients were started on physical therapy with "closed chain" rehabilitation and given nonsteroidal anti-inflammatory medications. Patients then underwent weekly follow-up with serial examinations and completion of a visual analog pain/motivation questionnaire. At the completion of training (6 to 8 weeks after study initiation), all charts were collected and statistically analyzed with analysis of variance (ANOVA). Eight patients were removed from the study group because of insufficient follow-up or failure to complete training (correlated with low motivation scales). There was no significant difference between the groups regarding change in pain throughout the study. The only statistically significant item was the proportion of females presenting with anterior knee pain (2.7% versus 1.4% incidence). Two patients voluntarily separated (disenrolled) due to incapacitating anterior knee pain at the completion of the study. Both of these patients were assigned to the Palumbo group. Despite manufacturer claims, these two orthotics do not appear to be effective in controlling anterior knee pain in this basic trainee populations.
Bismuth kagome sublattice distortions by quenching and flux pinning in superconducting <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:msub><mml:mi>RbBi</mml:mi><mml:mn>2</mml:mn></mml:msub></mml:math> (2021)

The properties of ${\mathrm{RbBi}}_{2}$, a 4.15 K superconductor, were investigated using magnetic field, pressure, and neutron diffraction. Under hydrostatic pressure, an almost 50% reduction of ${T}_{c}$ is observed, linked to a low Debye temperature estimated at 165 K. The resistivity and magnetic susceptibility were measured on quenched and slow-cooled polycrystalline samples. The resistivity follows a low temperature power-law dependence in both types of samples, while the diamagnetic susceptibility, $\ensuremath{\chi}$, is dependent on the sample cooling history. Slow-cooled samples have $\ensuremath{\chi}=\ensuremath{-}1$ while quenched samples have $\ensuremath{\chi}<\ensuremath{-}1$ due to grain size differences. Evidence of the effects of the cooling rate is also discerned from the local structure, obtained by neutron diffraction and the pair density function analysis. Slow-cooled samples have structurally symmetric Bi hexagons, in contrast to quenched samples in which disorder is manifested in periodic distortions of the Bi hexagonal rings of the kagome sublattice. Disorder may lead to flux pinning that reduces vortex mobility, but ${T}_{c}$ remains unaffected by the cooling rate.