gebhart/patrepeval huggingface dataset:
Cytokine regulation of experimental intestinal inflammation (1994)

Cytokines are important mediators of intestinal inflammation and the local and systemic manifestations associated with gut injury. This review focuses on recent developments in cytokine regulation and activities in experimental intestinal inflammation with emphasis on the balance between pro- and anti-inflammatory cytokines. The influence of local expression of interleukin-1 and its physiological antagonist, the interleukin-1 receptor antagonist, as well as T-helper lymphocyte subsets in determining the chronicity of intestinal inflammation and infection is discussed along with genetic determinants of these balances. The effects of interleukin-1 on physiologic abnormalities associated with inflammation are summarized. The mechanisms by which cytokines regulate tissue injury and mediate genetic susceptibility in experimental intestinal inflammation provide new insights into the pathogenesis of inflammatory bowel disease.
Hysterosalpingography with a new contrast medium. (1989)

This article reports on the use of iotrolan--a new contrast medium and the first dimeric, nonionic, hexaiodinated, water-soluble preparation--in hysterosalpingography. This randomized, double-blind study compared an ionic and a nonionic monomeric preparation. The better results were achieved with iotrolan. Its unusual lack of local irritation and its high contrast quality, especially definition of contrast, merit particular mention.
N,N-Bis(2-hydroxybenzyl)arylamines: Condensation of Saligenin with Primary Aromatic Amines<sup>1</sup> (1959)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTN,N-Bis(2-hydroxybenzyl)arylamines: Condensation of Saligenin with Primary Aromatic Amines1MIYOSHI NODACite this: J. Org. Chem. 1959, 24, 9, 1209–1212Publication Date (Print):September 1, 1959Publication History Published online1 May 2002Published inissue 1 September 1959https://pubs.acs.org/doi/10.1021/jo01091a011https://doi.org/10.1021/jo01091a011research-articleACS PublicationsRequest reuse permissionsArticle Views141Altmetric-Citations6LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Preimplantation embryo development in vitro: cooperative interactions among embryos and role of growth factors. (1990)

We have established a model that shows cooperative interaction among preimplantation embryos and the role of growth factors on their development and growth. Two-cell mouse embryos cultured singly in 25-microliters microdrops had inferior development to blastocysts and lower cell numbers per blastocyst compared with those cultured in groups of 5 or 10. The inferior development of singly cultured embryos was markedly improved by addition of epidermal growth factor (EGF) or transforming growth factor alpha or beta 1 (TGF-alpha or TGF-beta 1) to the culture medium. The stage of embryonic development, primarily affected by these treatments, was between eight-cell/morula and blastocyst. Furthermore, blastocysts developed from eight-cell embryos cultured in groups or singly in the presence of EGF showed a higher incidence of zona hatching compared with those cultured singly in the absence of EGF. Detection of EGF receptors on the embryonic cell surface at eight-cell/morula and blastocyst stages suggests beneficial effects of EGF or TGF-alpha on preimplantation embryo development and blastocyst functions. Insulin-like growth factor I (IGF-I) had no influence on embryo development. To further document the cooperative interactions among embryos, the volume of the culture medium was doubled to 50 microliters. This increase in culture volume was even more detrimental to the development of singly cultured embryos. However, this detrimental effect was significantly reversed by EGF and reversed even more markedly by a combination of EGF and TGF-beta 1 but not by TGF-beta 1 alone. Although TGF-beta 1 plus IGF-I caused a modest improvement of embryo development, the response was not as great as shown by EGF alone. Furthermore, IGF-I had no additive effect on EGF-induced embryonic development. The study presents clear evidence that specific growth factors of embryonic and/or reproductive tract origin participate in preimplantation embryo development and blastocyst functions in an autocrine/paracrine manner.
Photoemission of Cooper Pairs from Aromatic Hydrocarbons (2012)

We report the discovery of the formation of an electron Cooper pair approximately 40 eV above the double-ionization threshold in benzene, naphthalene, anthracene, and coronene after absorption of a single photon. We have measured the ratios of doubly to singly charged parent ions of the above mentioned molecules as well as pyrrole and furan by using monochromatized synchrotron radiation up to 100 eV above the corresponding thresholds. We also recorded photoelectron spectra of benzene and naphthalene at selected energies. The electron-pair formation is based on the specific structure of the molecules and does not exist for pyrrole and furan.
Measurement of Resonant-Cavity Characteristics (1953)

The circuit properties of a resonant cavity are effectively described by its loaded Q, unloaded Q, and shunt resistance. One method of Q measurement depends on an accurate knowledge of the variation of VSWR as a function of frequency in a transmission line terminated by the resonant cavity. A method of measuring shunt resistance along any path in the cavity entails accurate observation of the resonant-frequency shifts caused by an obstacle placed at points along the path. Therefore, both measurements require an AFC system with good stability and high resolution. The parameters of a re-entrant cavity with apertures are considered and the associated experimental setup is described.
The devolution of functional analysis (1983)

article Free Access Share on The devolution of functional analysis Authors: Ken Meyer British Gas British GasView Profile , John Doughry Honeywell Information Systems, Ltd Honeywell Information Systems, LtdView Profile Authors Info & Claims ACM SIGMOD RecordVolume 13Issue 3April 1983 pp 65–91https://doi.org/10.1145/984532.984538Published:01 April 1983Publication History 1citation137DownloadsMetricsTotal Citations1Total Downloads137Last 12 Months4Last 6 weeks1 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my Alerts New Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteeReaderPDF
Pushing the Right Buttons: Improving Efficacy of Therapeutic DNA Vectors (2017)

Gene therapy represents a potent therapeutical application for regenerative medicine. So far, viral and nonviral approaches suffer from major drawbacks hindering efficient gene therapeutic applicability: the immunogenicity of viral systems on the one hand, and the low gene transfer efficiency of nonviral systems on the other hand. Therefore, there is a high demand for improvements of therapeutical systems at several levels. This review summarizes different DNA vector modifications to enhance biological efficacy and efficiency of therapeutical vectors, aiming for low toxicity, high specificity, and biological efficacy-the cornerstones for successful translation of gene therapy into the clinic. We aim to provide a step-by-step instruction to optimize their vectors to achieve the desired outcome of gene therapy. Our review provides the means to either construct a potent gene therapeutic vector de novo or to specifically address a bottleneck in the chain of events mandatory for therapeutic success. Although most of the introduced techniques can be translated into different areas, this review primarily addresses improvements for applications in transient gene therapy in the field of tissue engineering.
Quality Properties of Flax Fibers Retted with Enzymes (1999)

Flax that has been mechanically treated in an opener-blender to disrupt stem integrity is enzymatically retted with a series of enzyme formulations with different levels of Flaxzyme with or without ethylenediamine-tetra-acetic acid (EDTA) as a chelator. Samples are then characterized by light and transmission electron microscopy and fiber tests for micronaire, strength (g/tex), and elongation. Unretted control fibers are off scale for micronaire and consist of fiber bundles with associated epidermis/cuticle fragments. Structurally, the lowest level of Flaxzyme used, i.e., 0.05% (w/v), plus 50 mmol EDTA produces ultimate fibers and bundles of various sizes without evidence of associated epidermis/cuticle. This formulation yields flax fibers with similar micronaire values and about 34% more strength than the recommended level of 0.3% Flaxzyme. A level of 3.0% Flaxzyme extensively removes middle lamellae from the bundles, produces the smallest micronaire values, and reduces strength to about 30% of fibers treated with 0.05% Flaxzyme plus chelator. Variations in fiber properties with the different formulations suggest that pectin degradation varies for different regions of the bast tissues and that specific strategies for improving enzymatic retting can be developed. Results show that fiber quality tests for cotton are useful in differentiating formulations for enzymatic retting of flax, and 0.05% Flaxzyme plus 50 mmol EDTA is the most efficient retting formulation.
Irreversible enzyme inhibitors. CLIII. Proteolytic enzymes. 11. Inhibition of guinea pig complement by substituted phenoxyacetamides (1969)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTIrreversible enzyme inhibitors. CLIII. Proteolytic enzymes. 11. Inhibition of guinea pig complement by substituted phenoxyacetamidesBernard Randall Baker and Jeffrey A. HurlbutCite this: J. Med. Chem. 1969, 12, 3, 415–419Publication Date (Print):May 1, 1969Publication History Published online1 May 2002Published inissue 1 May 1969https://doi.org/10.1021/jm00303a017RIGHTS & PERMISSIONSArticle Views52Altmetric-Citations5LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (445 KB) Get e-Alerts Get e-Alerts
A zigbee-based home automation system (2009)

In recent years, the home environment has seen a rapid introduction of network enabled digital technology. This technology offers new and exciting opportunities to increase the connectivity of devices within the home for the purpose of home automation. Moreover, with the rapid expansion of the Internet, there is the added potential for the remote control and monitoring of such network enabled devices. However, the adoption of home automation systems has been slow. This paper identifies the reasons for this slow adoption and evaluates the potential of ZigBee for addressing these problems through the design and implementation of a flexible home automation architecture. A ZigBee based home automation system and Wi-Fi network are integrated through a common home gateway. The home gateway provides network interoperability, a simple and flexible user interface, and remote access to the system. A dedicated virtual home is implemented to cater for the system's security and safety needs. To demonstrate the feasibility and effectiveness of the proposed system, four devices, a light switch, radiator valve, safety sensor and ZigBee remote control have been developed and evaluated with the home automation system.
Polyethylenimine-functionalized magnetic amorphous carbon fabricated from oil palm leaves as a novel adsorbent for Hg(II) from aqueous solutions (2018)

PEI (polyethylenimine) functionalized magnetic amorphous carbon thin film nano composite (Fe3O4-PEI-ACTF NC), was successfully synthesized and characterized by High Resolution Transmission Electron Microscope (HR-TEM), X-ray diffraction (XRD), Fourier-transform infrared spectrometer (FTIR), and Thermo gravimetric analysis (TGA). The synthesized nano composite Fe3O4-PEI-ACTF was developed as a highly efficient adsorbent for Hg(II) from aqueous samples. Effect of pH, contact time, adsorbent dose, initial concentration and temperature were investigated and optimized through batch adsorption technique. Besides, good magnetic performance of Fe3O4-PEI-ACTF NC makes it easily recovered from water with magnetic separation at low magnetic field. The adsorption kinetic data described well with the pseudo-second-order model and the equilibrium data fitted well to Langmuir isotherm model. The maximum adsorption capacity was 714 µg/g of Hg(II). Thermodynamic studies (ΔG° < 0, ΔH° > 0, ΔS° > 0) implied an endothermic and spontaneous adsorption process in nature. Furthermore, the excellent reproducibility indicated that Fe3O4-PEI-ACTF NC has a promising application for removing heavy metals from aqueous environments due to high adsorption capacity and easily and quick separation.
INVESTIGATION OF CHROMATOGRAPHIC PROPERTIES OF TITANIA. I. ON RETENTION BEHAVIOR OF HYDROXYL AND OTHER SUBSTITUENT ALIPHATIC CARBOXYLIC ACIDS: COMPARISON WITH ZIRCONIA (1999)

For demonstrating the presumption that on the hydrous zirconium oxide loaded porous polymer resin (Zr-gel) under alkaline pH the recognition of a position of hydroxyl or carboxyl group was ascribed to formation of a chelate ring, the retention behaviors of hydroxyl and other substituent aliphatic carboxylic acids were evaluated on titania synthesized in this laboratory and compared with those of zirconia provided by the manufacturer. The retention behavior supported the formation of chelate ring and suggested the priority of forming a five-membered ring. On comparison titania and zirconia, the distinct elution order was shown in retention behavior of 2-hydroxycarboxylic acids. It might be ascribed to the difference in the bond angle and distance between metal ion and two oxygen atoms of hydroxyl group and carboxylate anion on formation of chelate ring.
Essentials of Bayley Scales of Infant Development II Assessment (1999)

Overview of the Bayley Scales of Infant Development II. How to Administer the Bayley Scales of Infant Development II. How to Score the Bayley Scales of Infant Development II. How to Interpret the Bayley Scales of Infant Development II. Strengths and Weaknesses of the Bayley Scales of Infant Development II. Clinical Applications of the Bayley Scales of Infant Development II. Bayley Scales of Infant Development II Illustrative Case Reports. References. Annotated Bibliography. Index.
Representing shortest paths in graphs using Bloom filters without false positives and applications to routing in computer networks (2018)

A Bloom ﬁlter is data structure for representing sets in a compressed form, which has many applications. Bloom ﬁlters save time and space, but produce errors known as false positives.
In this thesis, a new approach is suggested. Instead of choosing labels for edges in graphs at random (as is done in the standard Bloom ﬁlter approach), labels for edges are chosen based on the graph and the position of an edge in the graph. It is shown that under some assumptions (the graph is known, and only shortest paths are encoded), there will be no false positives leading to a message being delivered to a wrong node.
5. The reaction of titanium halides with tertiary amines (1963)

G. W. A. Fowles and R. A. Hoodless, J. Chem. Soc., 1963, 33 DOI: 10.1039/JR9630000033
Fabrication of microlens in polymers with thermal reflow (2012)

[ANGLÈS] This study shows that it is possible to fabricate lenses with a very small diameter by depositing and melting the photoresist layer on a glass substrate. Thermal Reflow technique has been used to melt the top surface of lens and thus convex lenses have been developed in the form of spheres having diameter ranging from 50 - 175?m of thickness 10?m each. We present a study of melted microlens arrays and it concentrates on the production and measurement of microlens arrays. We explain the mechanism of fabricating microlens arrays and study their optical properties.
Size tunable fluorescent nano-graphite oxides: preparation and cell imaging applications (2013)

Fluorescent nano-graphite oxides (NGO) with different size distribution were prepared via a one-pot hydrothermal route using ultrasmall graphite powder as starting material and subsequently separated using dialysis tubes with different molecular weight cutoff. The biomedical applications of these NGO for cell imaging were further investigated. Fourier transform infrared spectra demonstrated that many functional groups including the hydroxyl group, carboxyl group and epoxy group were present on NGO, which endowed them with good water solubility. These NGO showed size-dependent photoluminescence and excellent biocompatibility with A549 cells. As evidenced by laser scanning confocal microscopy images, NGO could be internalized by A549 cells and located in the cytoplasm. Given their good water solubility, size tunable photoluminescence and excellent biocompatibility, these NGO should be promising for bioimaging and various biomedical applications.
Aurora Kinases and Potential Medical Applications of Aurora Kinase Inhibitors: A Review (2015)

Aurora kinases (AKs) represent a novel group of serine/threonine kinases. They were originally described in 1995 by David Glover in the course of studies of mutant alleles characterized with unusual spindle pole configuration in Drosophila melanogaster. Thus far, three AKs A, B, and C have been discovered in human healthy and neoplastic cells. Each one locates in different subcellular locations and they are all nuclear proteins. AKs are playing an essential role in mitotic events such as monitoring of the mitotic checkpoint, creation of bipolar mitotic spindle and alignment of centrosomes on it, also regulating centrosome separation, bio-orientation of chromosomes and cytokinesis. Any inactivation of them can have catastrophic consequences on mitotic events of spindle formation, alignment of centrosomes and cytokinesis, resulting in apoptosis. Overexpression of AKs has been detected in diverse solid and hematological cancers and has been linked with a dismal prognosis. After discovery and identification of the first aurora kinase inhibitor (AKI) ZM447439 as a potential drug for targeted therapy in cancer treatment, approximately 30 AKIs have been introduced in cancer treatment.
El español como lengua puente de culturas en el eje África, América, Europa (2014)

<p class="Predeterminado">Este número monográfico de la revista <strong>index.comunicación </strong>es el fruto de la colaboración de la Cátedra Unesco de Investigación en Comunicación y África (<a href="http://www.unescoafricom.es/">http://www.unescoafricom.es/</a><a href="http://www.unescoafricom.es/)y">)</a> <a href="http://www.unescoafricom.es/)y"> y</a> la Fundación Mujeres por África (<a href="http://www.mujeresporafrica.es/">http://www.mujeresporafrica.es/</a>) a partir de la firma de un artículo 83 suscrito en noviembre de 2013. <p class="Predeterminado">Dentro de este convenio una de las acciones fue la organización del Congreso “África con eñe” que se celebró el 29 y 30 de abril de 2014 en la Universidad Félix Houphouët-Boigny de Abdijan, Costa de Marfil y cuya información detallada puede verse en <a href="http://www.mujeresporafrica.es/hispanistas2014/hola.html">http://www.mujeresporafrica.es/hispanistas2014/hola.html</a> y <a href="http://www.unescoafricom.es/concluye-el-congreso-internacional-africa-con-n/">http://www.unescoafricom.es/concluye-el-congreso-internacional-africa-con-n/[1]</a>. <div><br /><hr size="1" /><div><p class="Notaalpie"><a href="file:///C:/JCS/jcs/JCS/C%C3%A1tedra%20UNESCO/%C3%81frica%20con%20%C3%B1/Introducci%C3%B3n%20y%20conclusiones%20Index%20(3).docx#_ftnref1">[1]</a> Tienen ya una cierta tradición los Congresos Ibero-Africano de Hispanistas, convocados por la Universidad de Navarra y que tuvieron lugar en Dakar, Senegal (2009), en El Cairo, Egipto (2012) y en Fez, Marruecos (2014). La particularidad de estos congresos es que se centran fundamentalmente en la literatura y en especial en la del siglo de oro. <p class="Notaalpie"> </div></div>
Biomechanical and physiological comparison of barefoot and two shod conditions in experienced barefoot runners. (2009)

The data of this study support the assumption that changes in the foot-ground interface led to changes in running pattern in a group of experienced barefoot runners. The Fivefingers model seems to be effective in imitating the barefoot conditions while providing a small amount of protection.
Characterization of the interaction between the dark septate fungus <i>Phialocephala fortinii </i>and <i>Asparagus officinalis</i> roots (2001)

Phialocephala fortinii Wang & Wilcox is a member of root-inhabiting fungi known collectively as dark septate endophytes (DSE). Although very common and distributed worldwide, few studies have documented their interaction with roots on a structural basis. The objective of this study was to determine the early colonization events and formation of microsclerotia of P. fortinii in roots of Asparagus officinalis L., a species known to have DSE. A loose network of hyphae accumulated at the root surface, and coils formed around root hairs and external to epidermal cells overlying short cells of the dimorphic, suberized exodermis. Root penetration occurred via swollen, appressorium-like structures into epidermal cells where coiling of hyphae occurred along the periphery of the cells. Hyphae penetrated from the epidermis into short exodermal cells and from these into cortical cells. Hyphae colonized the cortex up to the endodermis and sometimes entered the vascular cylinder. Some root tips were colonized as well. Microsclerotia in epidermal and exodermal short cells accumulated glycogen, protein, and polyphosphate. Energy-dispersive X-ray spectroscopy on distinct bodies visible in microsclerotial hyphae revealed high levels of phosphorus.