gebhart/patrepeval huggingface dataset:
Glucocorticoids Inhibit Glucose Transport in Cultured Hippocampal Neurons and Glia (1990)

A classical action of glucocorticoids (GCs) is to inhibit glucose uptake into various peripheral tissues. Two recent reports suggest that GCs do the same in the brain. Because of the in vivo nature of those studies, it was impossible to determine whether this inhibition occurred at the blood-brain barrier, and/or within neurons and glia themselves. In order to answer this and other mechanistic questions, we examined the effects of GCs on glucose transport in primary brain cultures. We established that uptake of 14C-2-deoxyglucose into hippocampal cultures was linear over a 15-min period and was inhibited by D-glucose and the uptake inhibitor cytochalasin B. Using this system, we found the following. (1) Both corticosterone and dexamethasone inhibited uptake into cultures containing both neurons and glia. (2) The effect was dose-dependent; steroid concentrations in the nanomolar range inhibited uptake from 20 to 33%. The effect was time-dependent, with more than 4 h of steroid exposure needed for inhibition. (3) Non-GC steroids did not inhibit uptake. (4) The GC inhibition seemed to be mediated by the type II (glucocorticoid) corticosteroid receptor. The effect was blocked by a type II, but not a type I (mineralocorticoid) receptor antagonist. Moreover, corticosterone inhibited only at concentrations well above the Kd for the type I receptor. Finally, aldosterone inhibited transport when applied at concentrations that bound heavily to type II receptors. (5) Corticosterone did not inhibit uptake in hypothalamic, cerebellar or cortical cultures, despite the presence of corticosteroid receptors in these cultures. (6) GCs inhibited uptake in both neuron- and glia-enriched hippocampal cultures.
A (2014)

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Organic Transistors as a Basis for Printed Electronics (2009)

This chapter contains sections titled: Introduction What is an Organic Transistor? How Does an Organic Transistor Work and How Does it Distinguish Itself from a Conventional One? Basic Logical Integrated Circuits: Ring Oscillators Complex Organic Circuits: the 64-Bit RFID Tag Organic CMOS Circuits Printing Electronics Application and Future Prospects Summary and Prospects Acknowledgements References
Front Matter and Table of Contents (1980)

This entry contains the front cover, front matter and back cover.
[The effect of different types of oral contraceptives upon ovarian function (author's transl)]. (1976)

An investigation on the influence of different types of oral contraceptives upon serum gonadotropins, estradiol and progesterone was carried out in 10 volunteers. The effect of a change from a normophasic type preparation to a sequential preparation (Ovanon and Kombiquens) and from a combined preparation to a minipill (Neogynon and Exlutona) was studied. Two new 3-phase step-up preparations were also tested. Ovulation was inhibited in each case as the preovulatory LH-peak and the subsequent rise of serum progesterone were found to be missing. The basal LH- and FSH-secretion and serum estradiol were demonstrated to be significantly diminished in the volunteers taking combined and sequential preparations. The release of gonadotropines was not inhibited as much when the 3-phase step-up preparations (SHB 261 AB and SHB 264 AB) were used. When Exlutona was taken, the basal LH-secretion was lower than during the pre- and postovulatory phase of the normal cycle, but follicular development did not appear to be inhibited much as both FSH and estradiol were found to be in the normal range.
Visual inspection versus quantitative flow cytometry to detect aberrant CD2 expression in malignant T cells (2009)

CD2 expression by malignant T cells differed significantly from that of normal T-cells by CD2 ABC quantitation. The high variability in normal T-cell CD2 ABCs limited the determination of normal reference ranges and, thus, its utility in the diagnosis of T-cell neoplasia. However, examination of CD2 can help in detection of tumor cells when residual normal T cells are present for comparison. Moreover, the increased sensitivity of CD2 quantitation is valuable in confirming FCI cases where abnormalities in CD2 expression are difficult to appreciate by visual inspection alone.
On the design of an embedded biometric smart card reader (2008)

In this paper, a highly reliable embedded biometric smart card system with cryptography engine is proposed. We explain the system architecture of portable embedded biometric smart card reader to strengthen security for various consumer applications such as mobile cash card. Proposed biometric smart card system is embedded with 75 MHz 32-bit RISC, 6 channel smart card controller and advanced encryption system (AES) cryptography accelerator. It is devised to communicate with smart card with encrypted biometric data using international standard ISO-7816 and provides system peripherals such as LCD display controller and USB host interface. The proposed implementation shows a 70% performance improvement for decryption of protected biometric data compared to the software based smart card chipset and it is verified using 0.35 um CMOS process.
Compact microwave microstrip resonator bandpass filters for communication (2014)

Electromagnetic spectrum is becoming increasingly congested due to the rapid development of wireless and mobile communication in recent decades. Compact passband filters with good performance are highly demanded in communication. New techniques and solutions for designing the compact microstrip resonator filters are discovered and explored to improve the performance and to reduce the filter size. The theme of this thesis is the realisation of compact microstrip resonator bandpass filters for communication. They are hairpin resonator, triple-mode resonator and quadruple-mode resonator. Step-by-step design processes for each filter are given and accompanied by the simulated and experimental results to support the findings.
The Effects of Reaction Conditions on the Synthetics and Properties of Polypyromellitimide (1997)

Polypyromellitimide polymers have been prepared in a two-step process by polymerizing pyromellitic dianhydride with different molar ratios of diisocyanates, toluene 2,4-diisocyanate (TDI) and methylenediphenylene 4,4'-diisocyanate (MDI), in dimethylformamide. Intentionally adding water to the reaction medium to study the effect of adventitious water on the formation of polymer, it was found that the presence of water has an important influence upon the molecular weight of the polymer formed. Moreover, thermal cyclodehydration of polyamic acids results in the corresponding polypyromellitimides. The polymers are characterized by mechanical strength and thermal stability.
Target Oriented Directive Designature (2008)

The traditional marine designature process does not correct for far-field variations with the direction of propagation. We propose a simple and robust method to take this directivity into account. It is a trace-by-trace target-oriented technology which has the advantage of simultaneously respecting take-off and emergent angles, azimuth and receiver depth. A time variant application of this approach gives comparable results to a tau-p based correction valid at small azimuth only.
Low density lipoprotein uptake by macrophages in multiple sclerosis plaques: implications for pathogenesis (1994)

Low density lipoprotein (LDL), the major carrier of plasma cholesterol, may enter the parenchyma of early multiple sclerosis (MS) lesions as a result of blood-brain barrier damage. We have used antibodies against LDL and epitopes found in LDL oxidized by two peroxidative end-products, malondialdehyde (MDA) and 4-hydroxynonenal (4-HNE), to immunocytochemically stain MS plaques at different stages of pathology. Native LDL, epitopes of MDA-LDL, peptides of myelin basic protein and neutral lipid oil red O (ORO) staining were found to be co-localized within foamy macrophages in early and actively demyelinating MS plaques. Thus cholesterol esters, which are seen as Maltese crosses under polarized light in a proportion of foamy macrophages, appear to be derived from both LDL and myelin. ORO-negative astrocytes were strongly stained with the antibodies against 4-HNE-LDL and MDA-LDL, suggesting uptake of oxidatively modified protein products alone. Our findings suggest that a large proportion of the plasma LDL which enters the parenchyma of MS plaques is oxidatively modified in the lesion. Lipid peroxidation and oxidized LDL uptake by activated microglia and infiltrating macrophages in the early stages of MS plaque development may play important roles in demyelination.
The Effects of Learning, Forgetting, and Relearning on Decision Rule Performance in Multiproject Scheduling (1999)

ABSTRACT Product development occurs in multiproject environments where preemption is often allowed so that critical projects can be addressed immediately. Because product development is characterized by time‐based competition, there is pressure to make decisions quickly using heuristics methods that yield fast project completion. Preemption heuristics are needed both to choose activities for preemption and then to determine which resources to use to restart preempted activities. Past research involving preemption has ignored any completion time penalty due to the forgetting experienced by project personnel during preemption and the resulting relearning time required to regain lost proficiency. The purpose of this research is to determine the impact of learning, forgetting, and relearning (LFR) on project completion time when preemption is allowed. We present a model for the LFR cycle in multiproject development environments. We test a number of priority rules for activity scheduling, activity preemption, and resource assignment subsequent to preemption, subject to the existence of the LFR cycle, for which a single type of knowledge worker resource is assigned among multiple projects. The results of the simulation experiments clearly demonstrate that LFR effects are significant. The tests of different scheduling, preemption, and resource reassignment rules show that the choice of rule is crucial in mitigating the completion time penalty effects of the LFR cycle, while maintaining high levels of resource utilization. Specifically, the worst performing rules tested for each performance measure are those that attempt to maintain high resource utilization. The best performing rules are based on activity criticality and resource learning.
Early dexamethasone treatment for septic shock patients: a prospective randomized clinical trial (2007)

Early treatment with dexamethasone reduced the seven-day mortality among septic shock patients and showed a trend towards reduction of 28-day mortality.
Use of Hydrophobic Interaction Chromatography with a Non-Salt Buffer System for Impr oving Process Economics in Purification of Monoclonal Antibodies (2000)

One of the barriers to more prevalent application of hydrophobic interaction chromatography (HIC) for purification of monoclonal antibodies is that the sample often elutes at salt concentrations which require buffer exchange before the next purification method can be performed. The selectivity provided by HIC is often so powerful that the technique is used despite these limitations, but residual salts constrain process design nevertheless. This report describes a non-salt-based (NSB) binding buffer system that mimics the selectivity of salt-based HIC buffers, but does so at conductivities directly compatible with ion exchange chromatography (IEC). This makes it possible to apply HIC fractions directly to IEC without intermediate buffer exchange, greatly extending the flexibility of HIC with respect to sequential placement in multi-method purification schemes. Results are shown illustrating practical application of the non-salt-based system to multistep purification of monoclonal antibodies.
Elaidic acid, vaccenic acid and rumenic acid (c9,t11-CLA) determination in human plasma phospholipids and human milk by fast gas chromatography (2012)

An efficient fast gas chromatographic method for simultaneous determination of elaidic acid, vaccenic acid and rumenic acid contents in human plasma phospholipids and human milk was optimized and validated. Two capillary columns, RTX-2330 and SP-2560, both of high polarity but with different dimensions (40 m × 0.18 mm I.D. and 0.10 μm film thickness, and 75 m × 0.18 mm I.D. and 0.14 μm film thickness, respectively), were compared for the separation of these fatty acids within a complete fatty acid profile. Separation with the SP-2560 column gave the best results. In comparison with the commonly used 100 m × 0.25 mm × 0.20 μm columns, this new type of fast column allowed the separation of fatty acid methyl esters with the same resolution but in less time, 32.2 min. In addition, separation of the phospholipid fraction in human plasma samples was optimized by using 96-well extraction plates filled with an aminopropyl phase. Recoveries ranged between 95.8% and 103.7%. Intra-assay and inter-assay precision ranged between 0.76% and 8.87%. Application of this method showed that it is a rapid and reliable method for quick and correct identification and quantification of these fatty acids in routine analysis.
Skin: a natural history (2007)

List of Illustrations Acknowledgments Introduction 1 Skin Laid Bare 2 History 3 Sweat 4 Skin and Sun 5 Skin's Dark Secret 6 Color 7 Touch 8 Emotions, Sex, and Skin 9 Wear and Tear 10 Statements 11 Future Skin Glossary Notes References Index
Extending touch (2009)

Touch is a very intuitive modality for interacting with objects displayed on arbitrary surfaces. However, when using touch for large-scale surfaces, not every point is reachable. Therefore, an extension is required that keeps the intuitivity provided by touch: pointing. We will present our system that allows both input modalities in one single framework. Our method is based on 3D reconstruction, using standard RGB cameras only, and allows seamless switching between touch and pointing, even while interacting. Our approach scales very well with large surfaces without modifying them. We present a technical evaluation of the system's accuracy, as well as a user study. We found that users preferred our system to a touch-only system, because they had more freedom during interaction and could solve the presented task significantly faster.
Full-Scale Wind-Tunnel Tests of Blowing Boundary-Layer Control Applied to a Helicopter Rotor (1960)

A full-scale wind-tunnel test was conducted of two boundary-layer-control applications to a 44-foot diameter helicopter rotor. Blowing from a nozzle near the leading edge of the blades delayed retreating blade stall. Results also indicated that delay of retreating blade stall could be obtained by cyclic blowing with a lower flow rate than that required for continuous blowing. It was found that blowing applied through a nozzle at mid-chord had no effect on retreating blade stall.
Designing virtual environments for brain injury rehabilitation (2003)

Virtual Reality (VR) has shown great potential in various training applications. In the field of cognitive rehabilitation it has been shown that VR technology can become a useful complement to conventional rehabilitation techniques (e.g. Rizzo et al. (2002), Brown et al. (2002) and Kizony et al. (2002)). An important part of a brain injury patient’s rehabilitation process is practicing instrumental activities of daily living (IADL), such as preparing meals, cleaning, shopping and using a telephone. A pilot study by Lindén et al. (2000) came to the conclusion that activities like these can be practiced using desktop VR. The question addressed in this thesis is how a Virtual Environment (VE) should be designed to be a usable tool in brain injury rehabilitation. The thesis consists of three papers that describe three different studies that have been performed in order to further explore this area of research. Paper I describes the design of a practical VE application in the shape of a cash dispenser. A paper prototype was constructed which was first used to
A bottom-up approach to job recommendation system (2016)

Recommendation Systems are omnipresent on the web nowadays. Most websites today are striving to provide quality recommendations to their customers in order to increase and retain their customers. In this paper, we present our approaches to design a job recommendation system for a career based social networking website - XING. We take a bottom up approach: we start with deeply understanding and exploring the data and gradually build the smaller bits of the system. We also consider traditional approaches of recommendation systems like collaborative filtering and discuss its performance. The best model that we produced is based on Gradient Boosting algorithm. Our experiments show the efficacy of our approaches. This work is based on a challenge organized by ACM RecSys conference 2016. We achieved a final full score of 1,411,119.11 with rank 20 on the official leader board.
Ring laser detection of rotations from teleseismic waves (2000)

Horizontal and vertical rotational components of teleseismic surface and body waves are detected by large ring laser gyroscopes. This is illustrated with records from magnitudes 7.0 and 7.3 events at distances of 31 deg. and 42.6 deg. respectively. Phase comparisons with synchronous linear seismometer records confirm the gyroscopic coupling.
The Object Concept: An Introduction to Computer Programming Using C++ (1995)

From the Publisher:
The Object Concept makes computer programming more accessible and more relevant to novice programmers through its careful introduction to object-oriented programming using C++. The Object Concept applies common-sense, proven pedagogical techniques, and the latest technology to teaching how to solve problems with computers. The book provides the basic software engineering skills needed to write programs that are modular, readable, testable, and maintainable.
Inhibitory action of bisphosphonates on bone resorption does not involve the regulation of RANKL and OPG expression (2002)

The mechanism of inhibitory action of bisphosphonates on bone resorption is not fully elucidated. Osteoclast formation and activity are regulated by osteoblast-derived factors such as the osteoclast differentiating factor, receptor activator of NF-kappaB ligand (RANKL) and the inhibitor, osteoprotegerin (OPG). To investigate in vitro effects of bisphosphonates on mouse osteoblastic cells, we examined the expression levels of RANKL and OPG in the cells treated with alendronate or pamidronate (10(-8) approximately 10(-5) M) alone, or combined with 10 nM of 1,25-(OH)2VitD3 for 24 or 48 h. Various concentrations of alendronate and pamidronate did not change the mRNA expression of RANKL and OPG consistently irrespective of 1,25-(OH)2VitD3 presence. When added into cocultures of mouse osteoblastic cells and bone marrow cells, both alendronate and pamidronate inhibited osteoclast formation and bone resorption but failed to alter the RANKL and OPG mRNA expression. These results indicate that the inhibition of bone resorption by bisphosphonates is not mediated by the regulation of RANKL and OPG expression.
Thatch Accumulation in Bermudagrass as Influenced by Cultural Practices<sup>1</sup> (1984)

Abstract Excessive thatch accumulation is a serious problem in golf course putting greens and other intensively managed turfgrass areas. More effective procedues for thatch control are needed. The relationship between different cultural practices and thatch accumulation was studied on Dothan sand loam (fine‐loamy, siliceous, thermic Plinthic Paleudult) in an experimental putting green planted to three bermndagrasses [ Cynodon dactylon (L.) Pers. × C. transvaalensis Burtt‐ Davy] cultivars Tifdwarf, Tifgreen, and a selection called Dothan. Practices evaluated included N source, core aerification, vertical mowing, and sand topdressing. A multiple split plot experimental design allowed the evaluation of each individual practice in combination with all others. Effects of treatments on thatch were determined by measuring thatch depth and the compressibility of the turf surface with a thatch compression meter. Thatch accumulation, after three seasons, increased in the order: Tifgreen, Dothan, Tifdwarf. However, the effects of treatments on thatch accumulation were similar for all cultivars. Four topdressings per year reduced thatch accumulation more than a single topdressing and increased mat depth. Neither monthly aerification nor biweekly vertical mowing provided more thatch control than twice yearly application of the respective cultural practice. Fertilization with activated sewage sludge resulted in 14% more thatch than when NH 4 NO 3 was the N source. Within a given topdressing frequency, no differences in thatch accumulation occurred among N sources, levels of aerification, or vertical mowing. The regression of millimeters compressibility on thatch depth was not significant. Turf quality was not correlated with thatch depth. Tifdwarf had the greatest accumulation on thatch and also produced high turf quality ratings. Nitrogen source influenced turf quality more than other treatments. Activated sewage sludge produced superior turf quality, although more thatch was produced than when NH 4 NO 3 was applied. Cultural practices had no consistent effect on establishment of ‘Pennfine’ perennial ryegrass ( Lolium perenne L.) overseeded on the experimental green. Ammonium nitrate produced better ryegrass quality than activated sewge sludge. Plots fertilized with activated sewage sludge had significantly more annual bluegrass ( Poa annua L.) than those receiving NH 4 NO 3 . Core aerification, topdressing, nor vertical mowing frequency affected ryegrass quality or annual bluegrass occurren
Anomalous paramagnetism of copper acetate (1952)

Abstract The paramagnetic resonance spectrum of copper acetate is anomalous in that it resembles that of an ion of spin 1, and its intensity decreases as the temperature is lowered. The latter is correlated with the decreasing susceptibility found by Guha (1951). The following hypo­theses are suggested: (1) the crystalline field acting on each copper ion is similar to that in other salts such as the Tutton salts; (2) isolated pairs of copper ions interact strongly through exchange forces, each pair forming a lower singlet state and an upper triplet state, the latter only being paramagnetic. On this basis both the fine structure and the hyperfine structure of the spectrum have a simple explanation, and the theory also predicts a small initial split­ting of the triplet state of the same order as that found experimentally. The unit cell of the crystal contains two differently oriented pairs of ions, and, using an empirical value for the exchange parameter, fair agreement with the susceptibility measurements of Guha is obtained.
An Apparatus and Technique for the Forcible Silking of Spiders (1982)

(Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
Telemedical information systems (1999)

Telemedical information systems (TIS's) form the basis for telemedicine services as well as for health information services. This paper gives an introduction to the wide scope of TIS's and discusses examples for the different types of TIS's: patient-related TIS's, knowledge-related TIS's, and meta-TIS's. It concludes that for patient-related TIS's there is the need for a better integration of TIS's with other patient-centered information systems. For the other types of TIS's, more sophisticated retrieval techniques and better user interfaces for ordinary users are required. Furthermore, short descriptions of our own projects are given: the patient-related TIS of the project TECSAC (distributed electronic patient record for cardiology) and the domain-specific knowledge-related TIS's ODITEB (radiological Internet text-book) and ENDOTEL-EIS (endoscopy information system).