gebhart/patrepeval huggingface dataset:
Expression of collagen binding integrins during cardiac development and hypertrophy. (1991)

The interaction between components of the extracellular matrix and the cell surface of cardiac myocytes appears to be regulated in part by receptors belonging to the integrin superfamily. The expression of the integrins was investigated at different stages of development of the heart as well as during cardiac hypertrophy. The characterization of the membrane proteins showed that a beta 1-integrin and associated alpha-chains were responsible for the interaction with collagen, laminin, and fibronectin. Immunoprecipitation data indicated that the presence of specific alpha-chains varied with development. These data were correlated with the ability of the isolated myocytes to attach to specific components of the extracellular matrix. The expression of the alpha 1-chain was prominently associated with the recognition of interstitial collagens. The presence of the alpha 1-chain was also associated with stages when collagen synthesis was increased, especially during fetal and neonatal growth and cardiac hypertrophy. Immunohistochemical localization with the antiserum against beta 1-integrin demonstrated its specific localization near the Z lines of cardiac myocytes. The localization both in vitro and in vivo indicated that the beta 1-integrin may play a role in myofibrillogenesis during development. The present immunohistochemical, cell adhesion, and biochemical data clearly indicate that integrins play a major role in the regulation of the interaction between cardiac myocytes and the extracellular matrix during development and disease.
Size Evolution and Control of Nanostructures in Laser-Directed Atomic Deposition* (2002)

A widely observed phenomenon in laser-directed growth of ordered arrays of nanostructures is that the feature size of fabricated nanostructures is much larger than the theoretically predicted value from calculating the atom accumulation due to laser focusing. We examine the diffusion effect on the size broadening by considering two major diffusion processes for deposited atoms, namely terrace diffusion and step-edge descending. A criterion is derived to predict the size evolution of nanostructures, which is a function of terrace diffusion barrier, Ehrlich-Schwoebel step-edge barrier, substrate temperature, deposition flux, and laser properties. Our predicted value of the feature width of aluminum quantum wires is in excellent agreement with the experimental findings. Research to predict the feature size for chromium and other materials is in progress. *Research sponsored by the Engineering Research Program of the Office of Basic Energy Sciences, U.S. Department of Energy. The Oak Ridge National Laboratory is managed for the U.S. DOE by UT-Battelle, LLC, under contract No. DE-AC05-00OR22725.
Advanced Software Protection Now (2010)

Software digital rights management is a pressing need for the software development industry which remains, as no practical solutions have been acclamaimed succesful by the industry. We introduce a novel software-protection method, fully implemented with today's technologies, that provides traitor tracing and license enforcement and requires no additional hardware nor inter-connectivity. Our work benefits from the use of secure triggers, a cryptographic primitive that is secure assuming the existence of an ind-cpa secure block cipher. Using our framework, developers may insert license checks and fingerprints, and obfuscate the code using secure triggers. As a result, this rises the cost that software analysis tools have detect and modify protection mechanisms. Thus rising the complexity of cracking this system.
Direct heterobenzylic fluorination, difluorination and trifluoromethylthiolation with dibenzenesulfonamide derivatives (2018)

Functionalization of heterocyclic scaffolds with mono- or difluoroalkyl groups provides unique opportunities to modulate drug p<i>K</i><sub>a</sub>, influence potency and membrane permeability, and attenuate metabolism. While advances in the addition of fluoroalkyl radicals to heterocycles have been made, direct C(sp<sup>3</sup>)-H heterobenzylic fluorination is comparatively unexplored. Here we demonstrate both mono- and difluorination of a range of alkyl heterocycles using a convenient process that relies on transient sulfonylation by the electrophilic fluorinating agent <i>N</i>-fluorobenzenesulfonimide. We also report heterobenzylic trifluoromethylthiolation and <sup>18</sup>F-fluorination, providing a suite of reactions for late-stage C(sp<sup>3</sup>)-H functionalization of drug leads and radiotracer discovery.
Study of the Adsorption of Dodecylammonium Chloride on a Labradorite (1967)

The adsorption isotherms of dodecylammonium chloride on silica and labradorite at natural pH and for various pH values were determined using a radioactive form of the reagent. The effect of Ca ion and Na ion on the adsorption of dodecylammonium chloride on silica and labradorite was also investigated.The results of adsorption tests of dodecylammonium chloride on both silica and labradorite indicated that there is a significant difference between both adsorption mechanisms. Namely, dodecylammonium ions adsorb at Stern layer on quartz surface as counter ions, on the other hand, dodecylammonium ions mainly adsorb on the labradorite surface by ion exchange, viz, by exchanging Na ions or Ca ions which are lattice cations of labradorite.The effect of pH on the adsorption of dodecylammonium ion on both silica and labradorite showed a similar tendency, however, the mechanisms differ from each other. On silica surface, H ion is potential determining ion and so controls adsordtion of dodecylammonium ion as counter ion in the Stern Layer. On the other hand, since Na ion and Ca ion which are lattice cations of labradorite are exchanged easily by H ion in acldic side, H ion is a competitor to the dodecylammonium ion for labradorite surface.The effect of Ca ion on the adsorption of dodecylammonium chloride on silica and labradorite was less than the effecf of H ion, but it was signmcant.
Benzimidazo[l,2-a]pyrazolo[l,5-c]quinazoline: a novel heterocyclic system (1996)

Heating of ethyl 3-[β-(benzimidazol-2-yl)hydrazine]-2-(polyfluorobenzoyl)acrylates in acetonitrile with potassium fluoride or triethylbenzylammonium chloride leads to derivatives of novel heterocyclic systems of benzimidazo[l,2-a]pyrazolo- [1,5-c]quinazoline.
RECENT ADVANCEMENT, TECHNOLOGY & APPLICATIONS OF MULTIPLE EMULSIONS (2013)

Multiple emulsions are complex polydispersed systems where both oil in water and water in oil emulsion exists simultaneously which are stabilized by lipophilic and hydrophilic surfactants respectively. The ratio of these surfactants is important in achieving stable multiple emulsions. Among water-in-oil-in-water (w/o/w) and oil-in-water-in-oil (o/w/o) type multiple emulsions, the former has wider areas of application and hence are studied in great detail. Formulation, preparation techniques and in vitro characterization methods for multiple emulsions are reviewed. Various factors affecting the stability of multiple emulsions and the stabilization approaches with specific reference to w/o/w type multiple emulsions are discussed in detail. Favorable drug release mechanisms and/or rate along with in vivo fate of multiple emulsions make them a versatile carrier. It finds wide range of applications in controlled or sustained drug delivery, targeted delivery, taste masking, bioavailability enhancement, enzyme immobilization, etc. Multiple emulsions have also been employed as intermediate step in the microencapsulation process and are the systems of increasing interest for the oral delivery of hydrophilic drugs, which are unstable in gastrointestinal tract like proteins and peptides. With the advancement in techniques for preparation, stabilization and rheological characterization of multiple emulsions, it will be able to provide a novel carrier system for drugs, cosmetics and pharmaceutical agents. In this review, emphasis is laid down on formulation, stabilization techniques and potential applications of multiple emulsion system.
Temporosphenoidal Arachnoid Cyst: When Not to Operate. A Series of 8 Cases (2012)

Objectives: The intra-diploic arachnoid cyst is a benign and rare disease. The aim of the study is to describe the clinical and radiological features of arachnoid cysts involving the sphenoid and temporal bones and to propose a therapeutic management.
Tree mortality and Extreme Rainfall in the Amazon (2018)

Mesoscale Convective Systems (MCS) are responsible for severe rainfall in the Amazon and can produce strong descending winds that can uprooting or break trees the most dominant mode of tree mortality in the Amazon. Our results show that severe rainfall help to explain the observed residence time of woody biomass and tree mortality in the Amazon.
Elemental abundances in different solar regions from EUV observations (1988)

Abondance relative de C, N, O, Ne, Mg, Si, S dans differentes regions de la zone de transition du Soleil (trou coronal, region calme et region active) par l'analyse spectrale EUV de donnees spectroheliometriques emmagasinees par Skylab
Cover Image (2018)

The cover image is based on the Original Article Detection of high-grade dysplasia, carcinoma in situ and squamous cell carcinoma in the upper aerodigestive tract: Recommendations for optimal use and interpretation of narrow-band imaging, by Manon A. Zwakenberg et al., https://doi.org/10.1111/coa.13229.
High density single-channel seismic profiles obtained during KY05-06 cruise in the Sagami Bay, Japan (2005)

In May, 2005, intensive single channel seismic surveys have been successfully completed in Sagami Bay area, central Japan, during the KY05-06 cruise using R/V KAIYO of JAMSTEC (Japan Agency for Marine-Earth Science and Technology). We obtained 22 SCS profiles in the overall Sagami Bay area, and 37 shallow and deep profiles around the Hatsushima cold seep communities in the western Sagami Bay. Very clear acoustic images were captured down to 1 sec. (TWT) after some editing, band-pass filtering and time migration. We present here the seismic profiles obtained during the KY05-06 cruise.
Diels–Alder Reactions at Carbene Ligands: A Route to Olefin‐Carbene Complexes (1986)

Of interest in connection with olefin metathesis is the stable complex 3. As a methacrylate analogue, 1 reacts with cyclopentadiene to give the Diels-Alder adduct 2 and its exo isomer. Decarbonylation of 2 leads to 3, the first structurally characterized olefin-carbene-chromium complex.
Development of LiDAR-Based UAV System for Environment Reconstruction (2017)

In disaster management, reconstructing the environment and quickly collecting the geospatial data of the impacted areas in a short time are crucial. In this letter, a light detection and ranging (LiDAR)-based unmanned aerial vehicle (UAV) is proposed to complete the reconstruction task. The UAV integrate an inertial navigation system (INS), a global navigation satellite system (GNSS) receiver, and a low-cost LiDAR. An unmanned helicopter is introduced and the multisensor payload architecture for direct georeferencing is designed to improve the capabilities of the vehicle. In addition, a new strategy of iterative closest point algorithm is proposed to solve the registration problems in the sparse and inhomogeneous derived point cloud. The proposed registration algorithm addresses the local minima problem by the use of direct-georeferenced points and the novel hierarchical structure as well as taking the feedback bias into INS/GNSS. The generated point cloud is compared with a more accurate one derived from a high-grade terrestrial LiDAR which uses real flight data. Results indicate that the proposed UAV system achieves meter-level accuracy and reconstructs the environment with dense point cloud.
Responses of knee extensor muscles to leg press training of various types in human. (2013)

Responses of m. vastus lateralis to 8-week resistive training of various types at leg press mashine were investigated in 30 male subjects. Training loads were 25, 65 and 85% of one repetition maximum for low (LI), medium (MI), and high intensity (HI) training groups respectively, while angular velocities of contraction differed considerably between groups. The total work done during training session was identical. The maximum strengths during isokinetic knee extension in LI and HI groups were increased at most angular velocities. In group MI increments were obtained only during concentric contractions. Significant improvement of fatigue resistance and maximum oxygen consumption (V(O2max)) was seen only in group MI and LI, respectively. The training-related increase of cross-sectional area in type II fibers in m. vastus lateralis was in the order of HI > MI > LI group, and that of type I fibers was opposite. The increased myonuclear number was found for HI group. The data suggest that fiber hypertrophy, fatigue resistance and V(O2max) changes were related to the type of training.
Preliminary phased-array characterization of near-field military jet aircraft noise (2013)

Major developments over the past decade in aeroacoustic beamforming techniques provide more accurate estimates of jet noise source phenomena. In a recent experiment, near and mid-field measurements of an F-22A using linear and planar microphone arrays were taken at various engine conditions about the jet plume. To locate and provide accurate amplitude levels of jet noise sources, conventional beamforming techniques are used with various array shading methods. Equivalent source reconstructions are shown for different engine conditions, observation angles, and frequencies to explore the source region. In addition, different datasets from spatially separated arrays are combined for improved source reconstructions and to account for spatially dependent spectral content. These results are preliminary to further techniques—such as deconvolution methods—to better understand noise source mechanisms within the jet plume. [Work supported by ONR.]
The Effects of Cropping Regimes on Fungal and Bacterial Communities of Wheat and Faba Bean in a Greenhouse Pot Experiment Differ between Plant Species and Compartment (2017)

Many bacteria and fungi in the plant rhizosphere and endosphere are beneficial to plant nutrient acquisition, health, and growth. Although playing essential roles in ecosystem functioning, our knowledge about the effects of multiple cropping regimes on the plant microbiome and their interactions is still limited. Here, we designed a pot experiment simulating different cropping regimes. For this purpose, wheat and faba bean plants were grown under controlled greenhouse conditions in monocultures and in two intercropping regimes: row and mixed intercropping. Bacterial and fungal communities in bulk and rhizosphere soils as well as in the roots and aerial plant parts were analyzed using large-scale metabarcoding. We detected differences in microbial richness and diversity between the cropping regimes. Generally, observed effects were attributed to differences between mixed and row intercropping or mixed intercropping and monoculture. Bacterial and fungal diversity were significantly higher in bulk soil samples of wheat and faba bean grown in mixed compared to row intercropping. Moreover, microbial communities varied between crop species and plant compartments resulting in different responses of these communities toward cropping regimes. Leaf endophytes were not affected by cropping regime but bacterial and fungal community structures in bulk and rhizosphere soil as well as fungal community structures in roots. We further recorded highly complex changes in microbial interactions. The number of negative inter-domain correlations between fungi and bacteria decreased in bulk and rhizosphere soil in intercropping regimes compared to monocultures due to beneficial effects. In addition, we observed plant species-dependent differences indicating that intra- and interspecific competition between plants had different effects on the plant species and thus on their associated microbial communities. To our knowledge, this is the first study investigating microbial communities in different plant compartments with respect to multiple cropping regimes using large-scale metabarcoding. Although a simple design simulating different cropping regimes was used, obtained results contribute to the understanding how cropping regimes affect bacterial and fungal communities and their interactions in different plant compartments. Nonetheless, we need field experiments to properly quantify observed effects in natural ecosystems.
Herbicidal efficacy and selectivity of pyribenzoxim in turfgrasses (2006)

Three field trials were conducted from 2003–2004 at Utsunomiya University, Japan, to evaluate the safety and herbicidal activity of pyribenzoxim (benzophenone O ‐[2,6‐bis[(4,6‐dimethoxy‐2‐pyrimidinyl)oxybenzoyl]oxime) in turfgrass. Pyribenzoxim showed a high level of safety in bentgrass ( Agrostis palustris Huds.) and zoysiagrass ( Zoysia matrella ) ≤ 300 g ai ha −1 and it controlled various major grass weeds, including annual bluegrass ( Poa annua L.), large crabgrass ( Digitaria sanguinalis L.), and green foxtail ( Setaria viridis L.), and broadleaf weeds, including common dandelion ( Taraxacum officinale Weber), horseweed ( Erigeron canadensis L.), shepherd’s‐purse ( Capsella bursa‐pastoris (L.) Medic.), common chickweed ( Stellaria media L.), common lambsquarters ( Chenopodium album L.), creeping woodsorrel ( Oxalis corniculata L.), and common dayflower ( Commelina communis L.) by fall or spring application. In comparison with bispyribac‐sodium (sodium 2,6‐[bis(4,6‐dimethoxy‐2‐pyrimidin‐2‐yl)oxy]benzoate), pyribenzoxim showed a higher safety level in bentgrass and a stronger herbicidal activity on grass weeds; in particular, annual bluegrass and large crabgrass.
Mechanistic evidence for the Diels-Alder reaction from high-pressure kinetics (1970)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTMechanistic evidence for the Diels-Alder reaction from high-pressure kineticsCharles A. Eckert and R. A. GriegerCite this: J. Am. Chem. Soc. 1970, 92, 24, 7149–7153Publication Date (Print):December 1, 1970Publication History Published online1 May 2002Published inissue 1 December 1970https://pubs.acs.org/doi/10.1021/ja00727a021https://doi.org/10.1021/ja00727a021research-articleACS PublicationsRequest reuse permissionsArticle Views331Altmetric-Citations9LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
On-Road Ammonia Emissions Characterized by Mobile, Open-Path Measurements (2014)

Ammonia (NH3) is a key precursor species to atmospheric fine particulate matter with strong implications for regional air quality and global climate change. NH3 from vehicles accounts for a significant fraction of total emissions of NH3 in urban areas. A mobile platform is developed to measure NH3, CO, and CO2 from the top of a passenger car. The mobile platform conducted 87 h of on-road measurements, covering 4500 km in New Jersey and California. The average on-road emission factor (EF) in CA is 0.49 ± 0.06 g NH3 per kg fuel and agrees with previous studies in CA (0.3-0.8 g/kg). The mean on-road NH3:CO emission ratio is 0.029 ± 0.005, and there is no systematic difference between NJ and CA. On-road NH3 EFs increase with road gradient by an enhancement of 53 mg/kg fuel per percentage of gradient. On-road NH3 EFs show higher values in both stop-and-go driving conditions and freeway speeds with a minimum near 70 km/h. Consistent with prior studies, the on-road emission ratios suggest a highly skewed distribution of NH3 emitters. Comparisons with existing NJ and CA on-road emission inventories indicate that there may be an underestimation of on-road NH3 emissions in both NJ and CA. We demonstrate that mobile, open-path measurements provide a unique tool to help quantitatively understand the on-road NH3 emissions in urban and suburban settings.
Tritium Behavior Intentionally Released in the Radiological Controlled Room under the US-Japan Collaboration at TSTA/LANL (1998)

A series of planned tritium release experiments into the Tritium Systems Test Assembly (TSTA) tritium processing rooms (3000 m3), were performed under the US-Japan collaboration program at Los Alamos National Laboratory (LANL). These experiments were carried out to acquire data on the behavior of tritium in an actual tritium facility. These experiments were performed safely with no impact on the environment or worker safety using 37 GBq (1 Ci). The results showed that the migration of tritium within the facility was dominated by the residual airflow in the room and reached a uniform value in 30 ~ 40 minutes. After restoring the normal once through ventilation (5 air changes per hour), room tritium levels decreased to background in less than 1 hour. Residual surface contamination was detected (max. 1 Bq/cm2 level). Residual contamination levels were found to be in order of decreasing contamination: linoleum > epoxy coating > acrylic resin > butyl rubber > stainless steel, from soaking results. The surface contamination increase as a result of the tritium release, was reduced to background with the normal ventilation within a few days.
Adaptive Support of an Aircraft Panel (2015)

The vibro-acoustic behavior of large lightweight structures such as aircraft fuselage has to be tested, especially to improve active and passive noise control means. Acoustic transmission laboratories with reverberant and anechoic rooms supply reliable test conditions for aircraft panels of a size up to several square meters. Shock mounts support these panels to realize free or pinned boundary conditions with minor damping, which is sufficient at high frequencies. At low frequencies, the vibration of the whole fuselage has to be considered. Therefore the support of the panel under test should provide the same dynamic impedance as the fuselage to which the panel would be connected in the aircraft. This frequency-dependent boundary condition can be realized by an adaptive support. The paper describes a numerical investigation of this supported panel which should behave like integrated into an aircraft fuselage.