gebhart/patrepeval huggingface dataset:
Applying Deep Neural Network (DNN) for Robust Indoor Localization in Multi-Building Environment (2018)

In the Internet of Things (IoT) era, indoor localization plays a vital role in academia and industry. Wi-Fi is a promising scheme for indoor localization as it is easy and free of charge, even for private networks. However, Wi-Fi has signal fluctuation problems because of dynamic changes of environments and shadowing effects. In this paper, we propose to use a deep neural network (DNN) to achieve accurate localization in Wi-Fi environments. In the localization process, we primarily construct a database having all reachable received signal strengths (RSSs), and basic service set identifiers (BSSIDs). Secondly, we fill the missed RSS values using regression, and then apply linear discriminant analysis (LDA) to reduce features. Thirdly, the 5-BSSIDs having the strongest RSS values are appended with reduced RSS vector. Finally, a DNN is applied for localizing Wi-Fi users. The proposed system is evaluated in the classification and regression schemes using the python programming language. The results show that 99.15% of the localization accuracy is correctly classified. Moreover, the coordinate-based localization provides 50%, 75%, and 93.10% accuracies for errors less than 0.50 m, 0.75 m, and 0.90 m respectively. The proposed method is compared with other algorithms, and our method provides motivated results. The simulation results also show that the proposed method can robustly localize Wi-Fi users in hierarchical and complex wireless environments.
Reducing Door-to-Needle Times Using Toyota’s Lean Manufacturing Principles and Value Stream Analysis (2012)

Lean process improvement methodology can expedite time-dependent stroke care without compromising safety.
The antibacterial activity of triclosan-impregnated storage boxes against Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Bacillus cereus and Shewanella putrefaciens in conditions simulating domestic use (2002)

Antimicrobial resistance has increased over the past decade causing concern for public health. Domestic antimicrobial products containing triclosan (2,4,4'-trichloro-2'-hydroxydiphenylether), a broad-spectrum antibacterial agent, were introduced in 1997 and have become popular among consumers. Cross-resistance to other antibacterial agents has been suggested as a possible consequence of their widespread use. Triclosan-impregnated plastic storage boxes were tested for activity against Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Bacillus cereus and Shewanella putrefaciens in various conditions, including some designed to simulate usual storage conditions. Results showed inhibition up to a factor of 106 of bacteria grown in direct contact with triclosan-impregnated plastic at 30 and 22 degrees C, but not at 4 degrees C. Triclosan resistance was not found to increase after repeated exposure in triclosan-impregnated boxes. Further investigation into the effect of triclosan-impregnated products on bacteria will increase understanding of domestic antimicrobial products and implications of their overuse.
Metadynamics convergence law in a multidimensional system (2010)

Metadynamics is a powerful sampling technique that uses a nonequilibrium history-dependent process to reconstruct the free-energy surface as a function of the relevant collective variables s . In Bussi [Phys. Rev. Lett. 96, 090601 (2006)] it is proved that, in a Langevin process, metadynamics provides an unbiased estimate of the free energy F(s) . We here study the convergence properties of this approach in a multidimensional system, with a Hamiltonian depending on several variables. Specifically, we show that in a Monte Carlo metadynamics simulation of an Ising model the time average of the history-dependent potential converge to F(s) with the same law of an umbrella sampling performed in optimal conditions (i.e., with a bias exactly equal to the negative of the free energy). Remarkably, after a short transient, the error becomes approximately independent on the filling speed, showing that even in out-of-equilibrium conditions metadynamics allows recovering an accurate estimate of F(s) . These results have been obtained introducing a functional form of the history-dependent potential that avoids the onset of systematic errors near the boundaries of the free-energy landscape.
Combining evolution strategy and gradient descent method for discriminative learning of bayesian classifiers (2009)

The optimization method is one of key issues in discriminative learning of pattern classifiers. This paper proposes a hybrid approach of the Covariance Matrix Adaptation Evolution Strategy (CMA-ES) and the gradient decent method for optimizing Bayesian classifiers under the SOFT target based Max-Min posterior Pseudo-probabilities (Soft-MMP) learning framework. In our hybrid optimization approach, the weighted mean of the parent population in the CMA-ES is adjusted by exploiting the gradient information of objective function, based on which the offspring is generated. As a result, the efficiency and the effectiveness of the CMA-ES are improved. We apply the Soft-MMP with the proposed hybrid optimization approach to handwritten digit recognition. The experiments on the CENPARMI database show that our handwritten digit classifier outperforms other state-of-the-art techniques. Furthermore, our hybrid optimization approach behaved better than not only the single gradient decent method but also the single CMA-ES in the experiments.
LXXVIII.—On the synthetical formation of closed carbon-chains (1885)

W. H. Perkin, J. Chem. Soc., Trans., 1885, 47, 801 DOI: 10.1039/CT8854700801
Software Engineering Challenges in Game Development (2009)

In software engineering (SE), video game development is unique yet similar to other software endeavors. It is unique in that it combines the work of teams covering multiple disciplines (art, music, acting, programming, etc.), and that engaging game play is sought after through the use of prototypes and iterations. With that, game development is faced with challenges that can be addressed using traditional SE practices. The industry needs to adopt sound SE practices for their distinct needs such as managing multimedia assets and finding the ldquofunrdquo in game play. The industry must take on the challenges by evolving SE methods to meet their needs. This work investigates these challenges and highlights engineering practices to mitigate these challenges.
Chemical modification of Bacillus thuringiensis activated  -endotoxin and its effect on toxicity and binding to Manduca sexta midgut membranes (1994)

The effect of chemical modification of aromatic and basic residues of the Bacillus thuringiensisinsecticidal CrylA(c) toxin on toxicity and receptor binding was studied. Modification of four or more of the 43 arginine residues resulted in abolition of toxicity towards Manduca sextaand Pieris brassicaein vivoand a Choristoneura fumiferanacell line in vitro.Modification of seven or more of the 27 tyrosine residues resulted in reduction of toxicity. Upon modification of most of the 10 tryptophan residues, toxicity was reduced. Modification of histidine residues had no effect on toxicity. A quantitative binding assay was developed and optimized to compare the binding of derivatives with native toxin to M. sextabrush border membrane vesicles. The reduction or abolition of toxicity observed upon selective modification of tyrosine or arginine residues was reflected in the binding abilities of the derivatives. However a non-toxic derivative, modified at tryptophan residues, retained its ability to bind vesicles. These results suggest that tyrosine and arginine residues are involved in the binding interaction of toxin with receptor but tryptophan residues are involved in some subsequent step.
Distribution of chicken anemia agent (CAA) and detection of neutralizing antibody in chicks experimentally inoculated with CAA. (1983)

When chicks were inoculated experimentally with chicken anemia agent (CAA) at 1 day of age, CAA was consistently recovered from all the organs, including the brain, up to 28 days postinoculation (PI). It was recovered from the brain and rectal contents even 49 days PI, when the experiment was finished. In chicks inoculated with CAA at 28 or 42 days of age, CAA was also proved to multiply in all the organs, except the brain. It disappeared from these chicks earlier than from the chicks inoculated at 1 day of age. Neutralizing antibody against CAA began to be detected 21 days PI in the chicks inoculated at 1 day of age, and 7 days PI in the chicks inoculated at 28 or 42 days of age.
Low divergence edge‐emitting laser with asymmetric waveguide based on one‐dimensional photonic crystal (2005)

We report on the lasers with a waveguide designed as a one-dimensional photonic band crystal with an irregularity (defect) to achieve low-divergence emission. Small vertical divergence less than 10º, high differential efficiency of 85% and CW output power of 1.8 W (10.6 W pulsed) have been obtained. For lasers with increased modal spot size very small vertical divergence emitting angle of 4.8º has been realized. (© 2005 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim)
Neighbourhood Belonging, Social Class and Social Media—Providing Ladders to the Cloud (2014)

The growth of social media over the past decade has transformed how we have interacted with the World Wide Web. This paper presents data from a research project coproduced with community organisations that had created an online archive through a Facebook site of a deprived neighbourhood in Edinburgh, Scotland. Framing the data from this site in the literature on class, place, stigma and belonging, the paper presents further evidence of the ‘we-being' of working-class residence as opposed to the elective belonging of middle class people, and the stigma towards working-class neighbourhoods from wider society. The paper concludes by highlighting the benefits of social media in producing a natural discussion about neighbourhoods and residence and the importance of creating ladders to the cloud for working-class neighbourhoods.
Non-negative differentially constrained entropy-like regularization (1996)

Classical maximum entropy is quite popular, not only because it is based on appropriate physical and phenomenological concepts, but also because it yields, among other things, a natural way in which to invoke, or even force, a positivity constraint. However, though it is known to converge with reasonable rates of convergence and to exhibit good stability properties, it is, from a practical point of view, flawed, because of its inherent shrinkage properties. This has been well documented along with the fact that it can, when the circumstances are appropriate, exhibit super-resolution behaviour. Thus, there is a clear need to examine whether the maximum entropy functional can be modified in a way which, on the one hand, removes the shrinkage difficulty and, on the other hand, guarantees good asymptotics for the oversmoothed solution as well as reasonable rates of convergence and appropriate stability.
The Intradialysis Hemodynamic Change and Sugar Control in Diabetic Hemodialysis Patients (2002)

Diabetic nephropathy is the leading cause of end-stage renal disease in many countries, including Taiwan. Diabetic patients characteristically experience more hemodynamic change during hernodialysis treatments. Hypotension develops rapidly and frequently in these patients. This problem becomes increasingly important as the growing population of diabetic patients are receiving (OR- are being maintained with HD treatments) maintenance hemodialysis. Sugar control also is a major issue for diabetic hemodialysis patients, since the glucose metabolism in the diabetic uremic patient is greatly altered. The alteration of the metabolic process in these patients has made daily control of blood sugar a difficult task in the care of the diabetic uremic patient. We reviewed the intra-dialytic hemodynamic change and sugar control in diabetic patients undergoing regular hemodialysis.
Differential requirement of Grb2 and PI3‐kinase in HGF/SF‐induced cell motility and tubulogenesis (1997)

Hepatocyte growth factor/scatter factor (HGF/SF) is a multifunctional cytokine that induces mitogenesis, motility, invasion, and morphogenesis of several epithelial and endothelial cell lines in culture. The receptor for HGF/SF has been identified as the Met tyrosine kinase. To investigate the signaling pathways that are involved in these events, we have generated chimeric receptors containing the extracellular domain of the colony stimulating factor-1 (CSF-1) receptor fused to the transmembrane and intracellular domains of the Met receptor (MET). Madin-Darby canine kidney (MDCK) epithelial cells, expressing the CSF-MET chimera dissociate, scatter and form branching tubules in response to CSF-1. However, cells expressing a mutant CSF-MET receptor containing a phenylalanine substitution for tyrosine 1356 (Y1356F) are unable to scatter or form branching tubules following stimulation with CSF-1. Tyrosine 1356 is essential for the recruitment of multiple substrates including Grb2, the p85 subunit of PI3-kinase, and PLCγ. To investigate the role of these signaling pathways, we have generated a mutant receptor that selectively fails to associate with Grb2, and have treated MDCK cells with potent inhibitors of PLCγ, PI3-kinase, and p70S6K, a downstream target of PI3-kinase. Our results implicate pathways downstream from PI3-kinase in cell dissociation and scatter, whereas pathways downstream from Grb2 are required for branching tubulogenesis in MDCK cells. J. Cell. Physiol. 173:196–201, 1997. © 1997 Wiley-Liss, Inc.
Indocyanine Green SPY Elite–Assisted Sentinel Lymph Node Biopsy in Cutaneous Melanoma (2014)

Diagnostic, II.
Immunonutrition in clinical practice: what is the current evidence? (2005)

The clinical trials of immunonutrition that we have undertaken have often been small, single centre studies. They have often been of limited statistical power and have often included patients with a variety of underlying disease states and at different points in the disease process. Three meta-analysis and a consensus statement in conjunction with a systematic review, have been performed in an attempt to overcome many of these limitations and understand further the clinical place for immunonutrition. However, there are still many questions regarding the place of immunonutrition in clinical practice that we still do not understand or have definitive answers to. For example, do we really know what is the optimal combination of nutrients and in what quantities they should be provided? Do we understand any potential interactions that might occur between these nutrients? What is the effect of the patients nutritional state? When and for how long should immunonutrition provided? What is the impact of the patients' underlying disease process and how does this interact with the provision of immunonutrition? At the present time whilst there is some indication and evidence as to which patients might benefit most, and as to those who may not benefit or even suffer detrimental effects from immunonutrition, we still can not answer these questions with any definitive authority. It is essential now that we undertake large well designed, well controlled multicentre studies with adequate statistical power to answer these questions. The indications are that immunonutrition has the potential to help patients but its place must be more clearly defined before its widespread acceptance into clinical practice is based on sound scientific evidence.
Progress and Future Direction to Improve Arizona's Reclaimed Wastewater Reuse Program (1999)

(No paper) The Arizona Department of Environmental Quality (ADEQ) is undertaking a major revision of its reclaimed wastewater reuse program in response to recommendations made by a citizens stakeholders group. This revision will result in an entirely new administrative scheme for regulating wastewater reuse in Arizona. In accordance with the recommendations, ADEQ is working to promulgate rules (1) adopting an improved set of reclaimed wastewater quality standards, (2) establishing an entirely new permitting process, and (3) codifying a more comprehensive set of technical standards for various types of end-use. This new administrative program will use, in part, the results from state-of-the-science studies in California and Arizona to streamline the permitting process for the applicant, eliminate duplicate or overlapping permits, better match reclaimed wastewater quality with different types of end-use, and more effectively protect public health and water quality. Progress to date in implementing these improvements will be described.
Design and Evaluation of a Soft and Wearable Robotic Glove for Hand Rehabilitation (2016)

In the modern world, due to an increased aging population, hand disability is becoming increasingly common. The prevalence of conditions such as stroke is placing an ever-growing burden on the limited fiscal resources of health care providers and the capacity of their physical therapy staff. As a solution, this paper presents a novel design for a wearable and adaptive glove for patients so that they can practice rehabilitative activities at home, reducing the workload for therapists and increasing the patient's independence. As an initial evaluation of the design's feasibility the prototype was subjected to motion analysis to compare its performance with the hand in an assessment of grasping patterns of a selection of blocks and spheres. The outcomes of this paper suggest that the theory of design has validity and may lead to a system that could be successful in the treatment of stroke patients to guide them through finger flexion and extension, which could enable them to gain more control and confidence in interacting with the world around them.
Free Radical Scavengers and Antioxidants from Lemongrass (<i>Cymbopogon citratus</i>(DC.) Stapf.) (2005)

Methanol, MeOH/water extracts, infusion, and decoction of Cymbopogon citratus were assessed for free radical scavenging effects measured by the bleaching of the 1,1-diphenyl-2-picryl-hydrazyl (DPPH) radical, scavenging of the superoxide anion, and inhibition of the enzyme xanthine oxidase (XO) and lipid peroxidation in human erythrocytes. The extracts presented effect in the DPPH and superoxide anion assay, with values ranging between 40 and 68% and 15-32% at 33 and 50 microg/mL, respectively, inhibited lipid peroxidation in erythrocytes by 19-71% at 500 microg/mL and were inactive toward the XO at 50 microg/mL. Isoorientin, isoscoparin, swertiajaponin, isoorientin 2' '-O-rhamnoside, orientin, chlorogenic acid, and caffeic acid were isolated and identified by spectroscopic methods. Isoorientin and orientin presented similar activities toward the DPPH (IC(50): 9-10 microM) and inhibited lipid peroxidation by 70% at 100 microg/mL. Caffeic and chlorogenic acid were active superoxide anion scavengers with IC(50) values of 68.8 and 54.2 microM, respectively, and a strong effect toward DPPH. Caffeic acid inhibited lipid peroxidation by 85% at 100 microg/mL.
Low temperature plasma process based on CO-rich CO/H2 mixtures for high rate diamond film deposition (1997)

A low temperature process (350 °C&lt;T&lt;500 °C) for nanocrystalline diamond film growth by microwave plasma-enhanced chemical vapor deposition has been developed that yields high rates (up to 2.5 μm/h) at relatively low plasma powers (0.5 kW). In contrast to the widely used H2-rich mixtures of CH4 or CO and H2 that exhibit monotonic decreases in the diamond growth rate as T is reduced from 800 to 400 °C, CO-rich mixtures of CO and H2 exhibit an increase and sharp maximum as T is reduced. The results suggest a different diamond growth mechanism from the CO-rich mixtures.
Comportement dans la vapeur d'eau à haute température du nitrure d'aluminium fritté. (1985)

International audience
Experimental Infection of Domestic Pigs with African Swine Fever Virus Lithuania 2014 Genotype II Field Isolate (2015)

An experimental infection was conducted to evaluate horizontal transmission, clinical, virological and humoral response induced in domestic pigs infected with African swine fever (ASF) genotype II virus circulating in 2014 into the European Union (EU). Ten naive pigs were placed in contact with eight pigs experimentally inoculated with the Lithuanian LT14/1490 ASF virus (ASFV) responsible for the first ASF case detected in wild boar in Lithuania in January 2014. Clinical examination and rectal temperature were recorded each day. Blood sampling from every animal was carried out twice weekly. Blood samples were examined for presence of ASF virus-specific antibodies and for determining the ASFV viral load. From the obtained results, it was concluded that the Lithuanian ASFV induced an acute disease which resulted in 94, 5% mortality. The disease was easily detected by real-time PCR prior to the onset of clinical signs and 33% of the animals seroconverted. All findings were in accordance with observations previously made in domestic pigs and wild boar when infected with ASF genotype II viruses characterized by a high virulence. One in-contact pig remained asymptomatic and survived the infection. The role of such animals in virus transmission would need further investigation.
PLASMA NITRIC OXIDE IN POSTTRAUMA CRITICAL ILLNESS (1997)

The time course of nitric oxide (NO) production in posttrauma critical illness was monitored, and its relationship to posttrauma "sepsis/SIRS" and physiologic patterns was described. Eighty multiple trauma patients were studied (514 samples) during their course in the intensive care unit (Injury Severity Score 27.6; 36% deaths). Plasma NO was estimated from NO3 + NO2 by the Griess test and compared with that of 10 healthy controls (HC). At each sample period, the patient was categorized as having bacteremic sepsis (BAC), sepsis syndrome (SS), or systemic inflammatory response syndrome (SIRS), and classified by Physiologic State Severity Classification (PSSC) into normal stress response (A-State), metabolic insufficiency (B-State), or respiratory insufficiency (C2-State), each quantified by their physiologic "distance" from reference state of recovering trauma patients (R-State). A severity index (L2PDEATH), based on a logistic model of state distances from R-State, quantified probability of death. Deaths showed increased NO (p < .05) over survivors or HC by day 3 posttrauma. A fall in vascular tone in deaths was related to the increased NO (p < .0001). The level of NO was higher as sepsis worsened: BAC > SS > SIRS > HC (all simultaneous, p < .05). PSSC and L2PDEATH correlated with incidence > HC and level of NO. In conclusion, the severity of posttrauma critical illness was classified by PSSC and quantified by the L2PDEATH index. These reflect progressively increased NO levels and suggest worsening sepsis status. The reduced total peripheral resistance (TPR)-to-flow relationship (vascular tone) in deaths characteristic of the more severe septic PSSC states appeared related to the increased plasma NO.