gebhart/patrepeval huggingface dataset:
Digital Three-Dimensional Atlas of Quail Development Using High-Resolution MRI (2007)

We present an archetypal set of three-dimensional digital atlases of the quail embryo based on microscopic magnetic resonance imaging (microMRI). The atlases are composed of three modules: (1) images of fixed ex ovo quail, ranging in age from embryonic day 5 to 10 (e05 to e10); (2) a coarsely delineated anatomical atlas of the microMRI data; and (3) an organ system-based hierarchical graph linked to the anatomical delineations. The atlas is designed to be accessed using SHIVA, a free Java application. The atlas is extensible and can contain other types of information including anatomical, physiological, and functional descriptors. It can also be linked to online resources and references. This digital atlas provides a framework to place various data types, such as gene expression and cell migration data, within the normal three-dimensional anatomy of the developing quail embryo. This provides a method for the analysis and examination of the spatial relationships among the different types of information within the context of the entire embryo.
Diagnosis and genotyping of <i>Helicobacter pylori</i> by polymerase chain reaction of bacterial DNA from gastric juice (2005)

This moderately sensitive technique could be employed with good efficiency, particularly in cases where it is difficult to obtain biopsy. Moreover, with this method bacterial genotype could be obtained.
[Clinical and molecular genetic analyses of congenital myotonic dystrophy]. (1997)

Myotonic dystrophy (DM) results from the amplification of an unstable CTG repeat in the 3' untranslated region of a transcript encoding an MtPK. Infants with congenital DM are shown to have on average a greater amplification of the CTG repeat than is seen in the noncongenital DM patients. The major clinical features of congenital DM are bilateral facial weakness, hypotonia, feeding difficulties, respiratory distress, delayed motor development and mental retardation. We present 6 patients, aged 11-35 years, from unrelated 5 families with clinical symptoms of congenital DM. The four of the patients were inherited paternally and only one showed a reduction in the CTG repeat size.
Is there a subgroup of long-term evolution among patients with advanced lung cancer?: Hints from the analysis of survival curves from cancer registry data (2014)

There is a subgroup showing long-term evolution among patients with advanced lung cancer. As survival rates continue to improve with the new generation of therapies, prognostic models considering short- and long-term survival subpopulations should be considered in clinical research.
[3 + 2] Cycloaddition of Nonstabilized Azomethine Ylides. 7. Stereoselective Synthesis of Epibatidine and Analogues<sup>,</sup> (1998)

Epibatidine (1) is synthesized by employing a [3 + 2] cycloaddition strategy as a key step via nonstabilized azomethine ylide 10, generated by one-electron oxidative double desilylation of N-benzyl-2,5-bis(trimethylsilyl)pyrrolidine (12). Cycloaddition of 10 with trans-ethyl-3-(6-chloro-3-pyridyl)-2-propenoate (22a) gives 26 in which the 6-chloro-3-pyridyl moiety is endo-oriented. Decarboxylation followed by debenzylation gives unnatural epimer 30 of 1. The required cycloadduct 33, in which 6-chloro-3-pyridyl moiety is exo-oriented, is obtained stereoselectively utilizing cis-ethyl-(6-chloro-3-pyridyl)-2-propenoate (22b) as dipolarophile. 30 is also converted to 1 by epimerization reaction using KO(t)()Bu. An alternative route involving conjugate addition of 6-chloro-3-iodo pyridine (37) to 36, obtained by cycloaddition of 10 with ethyl propiolate, is also suggested for the stereoselective synthesis of 1. A number of substituted epibatidines (38, 39, 40, 41, and 42) are synthesized through this strategy using appropriate dipolarophiles. Formal synthesis of the N-methyl homoepibatidine 48 and its epimer 46 is suggested from the cycloaddition of homologous azomethine ylide 44, derived from 43, with 22a and 22b, respectively.
A high-power diode-pumped Nd:YVO<sub>4</sub>slab amplifier with a hybrid resonator (2016)

We demonstrated a compact and efficient in-band diode-pumped Nd:YVO4 partially end-pumped slab (Innoslab) nanosecond amplifier based on a hybrid resonator. For the seeder source, a-6 W, 5 ns Q-switched laser with a repetition rate of 30 kHz was obtained with beam quality factors M2 < . A beam-shaping system consisting of cylindrical lenses was designed according to the different sizes of the active medium in two orthogonal directions. A maximum average output power of 77 W was obtained. The optical-to-optical efficiency was 27.9%. The beam quality factors M2 in the unstable and stable directions were 1.52 and 1.36, respectively.
Occurrence of Myeloma-Like γ-Globulin in C.S.F of A Four-Month Old Infant with Hydrocephalus (1964)

Myeloma-like immune globulins present themselves as narrow bands upon paper electrophoresis, and usually show a characteristic appearance in immunoelectrophoresis. Two antigenically different groups of myeloma proteins have been described: groups I and II. Recently, 60% of normal γ-globulin, throughout the mobility range of γ-globulin, has been shown to possess the antigen characteristic for group I, and 30% that for group II myeloma. Occurrence of myeloma-like proteins in the serum is not restricted to multiple myeloma. They may also be seen with other tumors, such as reticulum cell sarcoma, and various carcinomas. In addition, Sonnet and Milhaux have reported on the frequent occurrence of myeloma-like ("monoclonal") γ-globulins in the serum of adult Bantus with different diseases. When large amounts of a myeloma protein are present in the serum, it may be found in a much lower concentration in the spinal fluid.
Identification and Quantification of the Main Electrolyte Decomposition By-product in Na-Ion Batteries through FEC: Towards an Improvement of Safety and Lifetime (2016)

International audience
A Divide-and-Conquer Implementation of Three Sequence Alignment and Ancestor Inference (2007)

In this paper, we present an algorithm to simultaneously align three biological sequences with affine gap model and infer their common ancestral sequence. Our algorithm can be further extended to perform tree alignment for more se- quences, and eventually unify the two procedures of phylo- genetic reconstruction and sequence alignment. The nov- elty of our algorithm is: it applies the divide-and-conquer strategy so that the memory usage is reduced from O (n3) to O (n2), while at the same time, it is based on dynamic programming and optimal alignment is guaranteed. Tra- ditionally, three sequence alignment is limited by the huge demand of memory space and can only handle sequences less than two hundred characters long. With the new im- proved algorithm, we can produce the optimal alignment of sequences of several thousand characters long. We implemented our algorithm as a C program package MSAM . It has been extensively tested with BAliBASE, a real manually refined multiple sequence alignment database, as well as simulated datasets generated by Rose (Ran- dom Model of Sequence Evolution). We compared our re- sults with those of other popular multiple sequence align- ment tools, including the widely used programs such as ClustalW and T-Coffee. The experiment shows that MSAM produces not only better alignment, but also better ancestral sequence. The software can be downloaded for free at http://www.cse.sc.edu/phylo/MSAM.html
Surface reactivity of luminescent porous silicon (1993)

The effects of addition of a series of organoamine molecules on the luminescence of porous silicon has been examined by steady-state photoluminescence (PL) and Fourier transform infrared spectroscopies. These samples, prepared nonanodically via stain etching techniques and characterized by atomic force microscopy, show dramatic quenching of visible PL upon addition of dilute solutions of the above Lewis base adsorbates. The fractional changes in integrated PL intensity as a function of quencher concentration obey a simple equilibrium model, demonstrating Langmuir-type behavior from which equilibrium constants can be calculated. An observation concomitant with this loss of PL is a diminution of the silicon hydride stretching frequencies near 2100 cm−1.
Evaluation of a Novel Cryoablation System: In vivo Testing in a Chronic Porcine Model (2012)

The Cryo1 probe created transmural lesions on the beating heart, resulting in sustained conduction delay. Both probes had a similar performance in lesion geometry in this chronic animal model.
Overview of Results of Randomized Clinical Trials in Heart Disease (1988)

THIS is the second of a two-part article on the results of randomized trials of treatments designed to reduce mortality or major morbidity in heart disease. Our goal is to summarize the results of trials of common treatments on major outcomes in unstable angina, congestive heart failure, primary prevention with aspirin, and risk factor modification. This summary should provide useful background information against which clinicians must consider other information (eg, patient prognosis, risk of side effects, drug interactions, and specific clinical picture) in making decisions about individual patients. We do not deal in either article with trials of coronary artery bypass graft surgery for stable angina, trials of valve replacement, or congenital heart disease. The risk reductions are based on the odds ratio calculated by the Mantel-Haenszel method as applied to combining data from several trials. When event rates are low, the odds ratio and the relative risk are numerically
Video coding using motion classification (2008)

In this paper we present a video coding approach similar to texture- based methods but based on motion models. We consider motion perception properties instead of spatial texture properties of the video sequence. We integrate a motion classification algorithm to separate foreground objects containing noticeable motion from the background. These background areas are labeled as skipped areas that are not encoded. After decoding, frame reconstruction is performed by inserting the skipped background into the decoded frames. We are able to show as much as 15% an improvement over previous texture- based implementations in terms of video compression efficiency.
Evaluation of an Online Parallel Anomaly Detection System (2008)

The rapid and accurate detection of anomalies in network traffic has always been a challenging task, and is absolutely critical to the efficient operation of the network. The availability of numerous different detection algorithms makes it difficult to choose a suitable configuration. An algorithm may have a high detection rate for high rate attacks, but might behave unfavorably when faced with attacks with gradually increasing rates. This paper proposes an online parallel anomaly detection system that implements multiple anomaly detection algorithms in parallel to detect anomalies in real-time. The main idea is to aggregate the detection data from multiple algorithms to come up with a single anomaly metric. We evaluate this system with realistic attacks on the DETER testbed. Our results show improved true positive and false negative rates for both high intensity and slow-rise ramped floods. Furthermore, the system is able to detect attacks separated by as little as 15 seconds with a high true positive rate.
Weatherization Adoption in A Multilayer Social Network (2017)

Energy conservation in residential buildings has been a topic of interest in recent years because of their high levels of energy consumption. Weatherization is set of approaches that can be used to make buildings more energy-efficient, thereby helping residents lower their energy bills and improving environmental sustainability. However, there are two significant challenges associated with weatherization adoption: high upfront investment costs with a long payback period, and minimal awareness of weatherization and its benefits. This paper proposes an agent-based model that will allow researchers to explore residents' socially-motivated energy conservation decisions by providing a realistic social context via a multilayer social network and incorporating opinion dynamics based on the Susceptible-Exposed-Infected-Recovered epidemic model. Several experimental scenarios are run to demonstrate the model's potential to help policymakers determine how to encourage residential weatherization adoption.
Large-Scale Structural-Acoustic Analysis by the Sub-Space Superposition Synthesis Method. (1999)

A large-scale structural-acoustic analysis using sub-space superposition, in which a cavity is divided into several acoustic fields has been developed.This system uses a transfer-function mehtod to solve the acoustics efficiently.By solving simultaneous equations using the Gaussian-elimination method for each pair of neighboring acoustic sub-fields in sequence, calculation time and memory requirements are reduced.Calculation accuracy is the same as when calculating the entire acoustic field without dividing it.We created a closed acoustic model (a cavity model) and used it to numerically simulate acoustics.The simulation results show that the developed large-scale structural-acoustic analysis effectively reduces calculation resources.
Imino‐bridged heterocycles. VI . An unusual bridge structure resulting from an attempted ritter reaction in the benzo[5,6]cyclohepta[1,2‐c]pyridine system (1986)

Abstract An attempt to generate a tertiary carbinamine from 1 , through use of the Ritter reaction, resulted in the formation of the new bridged system 2 . This product apparently resulted from an intramolecular cyclization of the 5,6 olefin to the C‐11 nitrilium ion of 4 , followed by a second Ritter reaction at C‐6.
Optical And Electrical Properties Of D.C. Sputtered Sn 1-x Zr x O 2 Films (1990)

Thin films of Sn1-xZrx02 with x ranging from 0 to 0.33 were prepared by d.c. magnetron sputtering on room temperature substrates. From the measured transmission and reflection data the optical constants were calculated. The energy gap was analysed by McLean's method. The shift of the absorption edge towards high energies with increasing Zr amount was observed. Energy gaps were found in the range from 3.8 eV for SnO2 to 4.5 eV for Sn1-xZrx02 with x=0.33. Electrical conductivity was measured in the temperature range from 20 °C to 500 °C under vacuum conditions. It turned out that at low Zr concentrations (a few per cent) the prepared oxide layers show a remarkable electrical conductivity and simultaneously higher optical transmission as pure SnO2 layers prepared under similar conditions.
Abstracts of new publications (1947)

The purpose of this book is to supply citrus growers, horticulturists, packing-house workers, inspectors, investigators, and sellers of citrus fruits with a ready means of identifying and combatting citrus diseases, Nearly all parasitic and nonparasitic maladies are depicted and described. The text discusses distribution and importance of the diseases and places emphasis upon recognition of disease symptoms and the best methods known at the present time for then-control.
<title>Profilometry by spectral encoding of the optical axis</title> (1994)

A scanning optical profilometer without sample displacement along the optical axis has been developed. Light coming from a wide spectrum light source is focused onto the inspected surface through a Fresnel lens. Because of its dispersive properties, the foci are distributed along the optical axis as a function of wavelength. The reflected light is focused on a filtering pinhole like in confocal microscopy. The only wavelength exactly focused on the surface is transferred through this pinhole to the detection unit. The detected light is analyzed through a spectroscopic device and the surface height is deduced from the wavelength for which the light intensity is maximum. This punctual measure is repeated for each surface point by a lateral scanning of the surface. With respect to other focus sensing profilers, we replace a mechanical z displacement of the sample by a spectral inspection of the detected light. The setup and some experimental results are presented.
Evaluation of a System for Automatic Detection of Diabetic Retinopathy From Color Fundus Photographs in a Large Population of Patients With Diabetes (2008)

Automated detection of diabetic retinopathy using published algorithms cannot yet be recommended for clinical practice. However, performance is such that evaluation on validated, publicly available datasets should be pursued. If algorithms can be improved, such a system may in the future lead to improved prevention of blindness and vision loss in patients with diabetes.
Adaptive stabilization and disturbance rejection for first-order systems (2002)

We use a discontinuous adaptive control algorithm to achieve simultaneous stabilization and disturbance rejection for a first-order linear system. Lyapunov methods are used to prove stability of the closed-loop system and convergence to zero of the measurement. Closed-loop performance is compared to standard high-gain methods.
ChemInform Abstract: Annulation of Aromatic Imines via Directed C—H Activation with Wilkinson′s Catalyst. (2002)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Separation-sensitive measurements of morphology dependent resonances in coupled fluorescent microspheres (2010)

The inelastic emission spectrum of a single fluorescent microsphere (bead) exhibits resonances arising from whispering gallery modes. Two beads in close proximity form a coupled bisphere. Coherent coupling arises from each bead's evanescent field and leads to resonance splitting. Here we collect emission spectra of two coupled beads, with nearly identical diameters, as spacing between beads is varied. Using these size-matched beads allows us to probe resonance splitting under strong coupling conditions.
Passive electrical properties of multi-walled carbon nanotubes up to 0.1 THz (2007)

Metallic carbon nanotubes (CNTs) are promising as transmission lines or interconnects in radio-frequency nanoelectric circuits. This paper presents passive network properties of individual multi-walled carbon nanotubes (MWNTs) up to 110 GHz measured at room temperature. From the S-parameter data, frequency-dependent electric properties of the MWNT were extracted using an equivalent R-L-C circuit model. The ac impedance of the MWNT decreases significantly with increasing frequency, as predicted by earlier theoretical work. In particular, the equivalent resistance decreases a few hundred times. Our findings show that MWNTs can carry high-frequency currents much better than dc.
Digital CMOS IC's in 6H-SiC operating on a 5-V power supply (1998)

A CMOS technology in 6H-SiC utilizing an implanted p-well process is developed. The p-wells are fabricated by implanting boron ions into an n-type epilayer. PMOS devices are fabricated on an n-type epilayer while the NMOS devices are fabricated on implanted p-wells using a thermally grown gate oxide. The resulting NMOS devices have a threshold voltage of 3.3 V while the PMOS devices have a threshold voltage of -4.2 V at room temperature. The effective channel mobility is around 20 cm/sup 2//Vs for the NMOS devices and around 7.5 cm/sup 2//Vs for the PMOS devices. Several digital circuits, such as inverters, NAND's, NOR's, and 11-stage ring oscillators are fabricated using these devices and exhibited stable operation at temperatures ranging from room temperature to 300/spl deg/C. These digital circuits are the first CMOS circuits in 6H-SiC to operate with a 5-V power supply for temperatures ranging from room temperature up to 300/spl deg/C.
The Calvin cycle in cyanobacteria is regulated by CP12 via the NAD(H)/NADP(H) ratio under light/dark conditions (2005)

In Synechococcus PCC7942 cells grown in the dark, the concentrations of NAD(H) and NADP(H) were 128+/-2.5 and 483+/-4.0 microm, respectively, while those in the cells under light conditions were 100+/-5.0 and 649+/-7.0 microm, respectively. Analysis of gel filtration indicated that the change of the ratio of NADP(H) to NAD(H) in cyanobacterial cells under light/dark conditions controls the reversible dissociation of the PRK/CP12/GAPDH complex (approximately 520 kDa) consisting of phosphoribulokinase (PRK), CP12, and glyceraldehyde-3-phosphate dehydrogenase (GAPDH). S. 7942 CP12 lacked the two Cys residues essential for formation of the N-terminal peptide loop in the CP12 of higher plants, but the N-terminal region of S. 7942 CP12 had the ability to be associated with PRK. The growth of mutant cells in which the CP12 gene was disrupted by a kanamycin resistance cartridge gene was almost the same as that of wild-type cells under continuous light conditions. However, under the light/dark cycle (12 h/12 h), the growth of CP12-disrupted mutant cells was significantly inhibited compared with that of wild-type cells. The mutant cells showed a decreased rate of O2 consumption and an increased level of ribulose 1,5-bisphosphate compared with wild-type cells in the dark. These data suggest that under light and dark conditions, the oligomerization of CP12 with PRK and GAPDH regulates the activities of both enzymes and thus the carbon flow from the Calvin cycle to the oxidative pentose phosphate cycle.
Turbulence intensity in aortic stenosis: frequency characteristics and effects of alterations in left ventricular function. (1993)

Turbulent blood flow can occur downstream from a stenosis. The purpose of this study was to quantitate turbulence intensity and its frequency characteristics in the ascending aorta in adult patients with and without valvular stenosis, and to use extrasystoles to analyze the effects of changes in left ventricular function on turbulence. Turbulence intensity was determined from the digitized, high frequency oscillations seen in high fidelity pressure recordings of 25 patients with valvular aortic stenosis. The intensity of turbulence was quantitated as the root-mean-square (mmHg) of pressure fluctuations and as the total spectral power (mmHg2/beat) of the frequency spectrum between 25 Hz and 400 Hz. Frequency characteristics were summarized by the mean and median frequency of spectral power and partitioning the spectrum into 25 Hz segments. Ten adult patients without aortic valve or outflow tract abnormalities served as controls. Adult patients with aortic stenosis had significantly more turbulence in the ascending aorta than controls (total spectral power 1577 +/- 450 mmHg2 vs. 198 +/- 22 mmHg2, p < 0.01). Furthermore, the frequency distribution in aortic stenosis was biased towards higher frequencies (mean frequency 35 +/- 14 Hz vs 54 +/- 2 Hz, p < 0.001). Turbulence intensity in aortic stenosis demonstrated beat to beat modulation by left ventricular function. The total spectral power of a sinus beat was 1888 +/- 762 mmHg2, and fell to 137 +/- 63 mmHg2 in a weak premature beat, and rose to 3618 +/- 1178 mmHg2 in a potentiated post- extrasystolic beat (p = 0.01).(ABSTRACT TRUNCATED AT 250 WORDS)
Discovery of two novel HLA‐B alleles, B*46:13:03 and B*15:189, in two Taiwanese volunteer bone marrow donors by sequence‐based typing (2011)

We report here two novel HLA-B alleles, B*46:13:03 and B*15:189, discovered in two Taiwanese volunteer bone marrow donors. The sequence of B*15:189 has a nucleotide sequence possibly derived from a recombination event between HLA-B*39:01:01 and B*15:01:01:01, while the origin of the sequence B*46:13:03 was less obvious to postulate, considering the low frequency of B*46:13 in the general population and the silent mutations involved. Our report here adds further HLA polymorphism to the growing lists of HLA-B*46 and HLA-B*15 and provides an additional HLA information for donor search programme for patients undergoing transplant.