gebhart/patrepeval huggingface dataset:
Rhabdomyosarcoma. A new classification scheme related to prognosis. (1992)

We classified 159 cases of rhabdomyosarcoma (RMS) according to the conventional scheme adopted by the World Health Organization and a modified conventional scheme established at the National Cancer Institute (NCI), Bethesda, Md. The major modification in the NCI scheme was the inclusion of compact round-cell RMS with scant myogenesis in the group of alveolar RMS despite lack of an alveolar architecture. These tumors were previously considered to be embryonal RMS, but their cytologic features are quite different from those seen in embryonal RMS and are indistinguishable from those encountered in alveolar RMS. These tumors are referred to as "solid alveolar RMS." Survival curves were constructed with the method of Kaplan-Meier and compared with the unstratified and stratified methods of Mantel-Haenszel (with stratification factors being stage, site, and age) and with the Cox regression analysis. Both histologic schemes showed a statistically significant prognostic value in unstratified analyses, but the NCI scheme demonstrated prognostic value even in stratified analyses and in the Cox regression analysis in our series of cases. The data indicate that the NCI scheme can serve as a highly predictive, independent prognostic factor in RMS and that the alveolar category should be expanded to include the solid round-cell RMS, even in the absence of a classic alveolar architecture.
Eliminating structure misalignments using robust matching and image editing based on seam carving (2009)

In this paper, we propose an algorithm that generates a natural composite from the misaligned images. The image stitching for this purpose is usually performed in two steps: correspondence matching of salient features followed by appropriated warping or editing. The proposed correspondence matching problem is formulated as the one-dimensional registration along the stitching boundary, where an appropriate energy function is proposed. The designed energy function consists of three complementary terms that encode appearance, smoothness and ordering of points, whereas the existing method considers the edge strength and ordering. Then we develop an algorithm that makes several salient points move to desired positions by using seam carving/inserting, which produces visually pleasing results compared to the conventional warping methods with less computations. The experimental results show that the proposed method efficiently and robustly generates natural composite images.
A practical procedure for the preparation of crystalline α-and ß-2-deoxy-1,3,4,6-D-glucose tetraacetate and their biological evaluation (1999)

info:eu-repo/semantics/published
Neoclassical Tearing Modes. Invited Paper (2000)

Author: Buttery, R. J. et al.; Genre: Journal Article; Published in Print: 2000; Keywords: 27th EPS Conference on Plasma Physics and Controlled Fusion, Budapest, 2000-06-12 to 2000-06-16; Title: Neoclassical Tearing Modes. Invited Paper
MOSAIC-A Model for Computer-Supported Collaborative Work (1987)

The proliferation of personal and medium-sized computers, the widespread availability of data communication networks, and the need to support cooperative work among geographically dispersed individuals have motivated the recent development of distributed information-management environments (DIME). In this paper, we explore the functions and structure of DIMEs, describe the MOSAIC reference model for computer-supported collaborative work, and present an example of a prototype DIME designed to support collaborative decision making among individuals in distributed command-and-control environments.
The Primary Substrate Binding Site in the b′ Domain of ERp57 Is Adapted for Endoplasmic Reticulum Lectin Association (2004)

ERp57 is a member of the protein disulfide isomerase (PDI) family that is located in the endoplasmic reticulum (ER) and characterized by its specificity for glycoproteins. Substrate selection by ERp57 is dependent upon its formation of discrete complexes with two ER resident lectins, soluble calreticulin and membrane-bound calnexin. It is these two lectins that directly associate with glycoproteins bearing correctly trimmed oligosaccharide side chains. Thus, ERp57 is presented with a preselected set of substrates upon which it can act, and the specific binding of calreticulin and calnexin to ERp57 is pivotal to the functions of the resulting complexes. To gain further insights into the formation of these ERp57-ER lectin complexes, we have investigated the regions of ERp57 that are specifically required for its binding to calreticulin. Using a quantitative pull-down assay to investigate the binding of ERp57/PDI chimeras to calreticulin, we define the b and b' domains of ERp57 as the minimal elements that are sufficient for complex formation. This analysis further identifies a novel role for the distinctive C-terminal extension of ERp57 in reconstituting complex formation to wild type levels. Using our understanding of substrate binding to the b' domain of PDI as a paradigm, we show that alterations to specific residues in the b' domain of ERp57 dramatically reduce or completely abolish its binding to calreticulin. On the basis of these data, we propose a model where the region of ERp57 equivalent to the primary substrate binding site of archetypal PDI is occupied by calreticulin and suggest that the ER lectins act as adaptor molecules that define the substrate specificity of ERp57.
SYMBOL - A large experimental system exploring major hardware replacement of software (1899)

The SYMBOL system is the result of a major developmental effort to increase the functional capability of hardware. Part of the charter of the broad based project was to reexamine the traditional division between hardware and software, to reexamine the respective roles of program instruction and data storage, and to reduce the overall complexity and cost of computing. In order to adequately evaluate the concepts that had been developed it was concluded that an experimental, usable, real system must be built. The SYMBOL system, now operational, is the embodiment of this effort.
Video imaging of the sperm acrosome reaction during in vitro fertilization. (2011)

Mammalian spermatozoa become competent for fusion with oocytes while traveling through the female reproductive tract and the oocyte's extracellular investments. Recent studies highlighted the molecular mechanism of the sperm's interactions with the zona pellucida (ZP), the extracellular coat surrounding the oocyte. Fertilizing spermatozoa initiate the sperm acrosome reaction (AR), essential for zona penetration and fusion with the oocyte plasma membrane, before they reach the ZP. However, the exact condition of spermatozoa that leads to successful penetration of the ZP remains unknown. We performed microscopic observations of in vitro fertilization with genetically (EGFP) and chemically (antibody and lectin) labeled spermatozoa to monitor the progression of the AR. Spermatozoa exhibiting EGFP(-)/PNA(+) prior to binding to the ZP initiated zona penetration. This result suggests that spermatozoa that have undergone the AR are still capable of binding and penetrating the ZP.
AHDAM: An Asymmetric Homogeneous with Dynamic Allocator Manycore Chip. (2011)

The future high-end embedded systems applications are characterized by their computation-intensive workloads, their high-level of parallelism, their large data-set requirements, and their dynamism. Those applications require highly-efficient manycore architectures. In response to this problem, we designed an asymmetric homogeneous with dynamic allocator manycore architecture, called AHDAM chip. AHDAM chip exploits the parallelism on all its granularity levels. It implements multithreading techniques to increase the processors' utilization. We designed an easy programming model and reused an automatic compilation and application parallelization tool. To study its performance, we used the radio spectrum sensing application from the telecommunication domain. On a simulation framework, we evaluated sequential and parallel versions of the application on 2 platforms: single processor, and AHDAM chip with a variable number of processors. The results show that the application on the AHDAM chip has an execution time 574 times faster than on the single-processor system, while meeting the real-time deadline and occupying 51.92 mm2 at 40 nm technology.
The Effects of 53 Hours of Sleep Deprivation on Moral Judgment (2007)

These findings suggest that sleep deprivation impairs the ability to integrate emotion and cognition to guide moral judgments, although susceptibility to the effects of sleep loss on this ability is moderated by the level of emotional intelligence.
[Changes in the activity of mixed-function oxidases in workers in an artificial silk plant]. (1992)

The carbon sulfide effect on the oxidase mixed function activity (OMF) is studied in 172 workers from plant producing artificial silk, distributed in 5 groups, according to index of exposure, defining the strength and duration of the toxic effect. The OMF activity is evaluated by giving aminopyrine and determining its metabolites in urine. The exposure to carbon sulfide effects the OMF activity. It is expressed by inhibition of OMF, manifested most frequently in quality controllers and transporters (31%) and heads of shift and section foremen (25%). In the remaining groups the OMF inhibition, estimated after the first aminopyrine metabolite, varies from 16% to 21%. Even more significant are the changes in the excretion of the second metabolite, where the deviation of the referent values reaches 56% for IInd group, 55% in IIIrd group and 45% in Ist group.
THE EFFECT OF RACE/ETHNICITY ON PROSTATE CANCER TREATMENT OUTCOME IS CONDITIONAL: A REVIEW OF WAYNE STATE UNIVERSITY DATA (2004)

Race/ethnicity as an independent predictor of prostate cancer is conditional and dependent on age, stage and year of diagnosis. Year of diagnosis is associated with a stage shift to earlier staged prostate cancer from the early to late 1990s. In general, study cohorts are often subranges of the entire spectrum of prostate cancer that are limited by these factors, especially stage at diagnosis and treatment. If diagnosed and treated early enough, although there is evidence suggesting that AAMs have more aggressive disease biologically, the role of race as a factor in outcome is significantly decreased. The age factor is more complex and must be discussed in more detail.
Impurity Absorption Spectroscopy in<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mmultiscripts><mml:mrow><mml:mi mathvariant="normal">S</mml:mi><mml:mi mathvariant="normal">i</mml:mi></mml:mrow><mml:mprescripts/><mml:none/><mml:mn>28</mml:mn></mml:mmultiscripts></mml:math>: The Importance of Inhomogeneous Isotope Broadening (2003)

We report high-resolution infrared absorption spectra of the neutral donors phosphorus and lithium, and the neutral acceptor boron, in isotopically pure 28Si crystals. Surprisingly, many of the transitions are much sharper than previously reported in natural Si. In particular, the 2p(0) line of phosphorus in 28Si has a full width at half maximum of only 4.2 microeV, about 5 times less than the narrowest 2p(0) line previously reported for natural Si, making it the narrowest shallow impurity transition yet observed. The widely held assumptions that the impurity transitions previously reported in high quality samples of natural Si revealed the true, homogeneous linewidths, are thus shown to be incorrect. The sharper transitions in 28Si also reveal new substructures in the boron and lithium spectra.
ATOM-PROBE MASS ANALYSIS WITH A SIGNAL HEIGHT DISCRIMINATING TIMER (1986)

At a high evaporation rate the probability of simultaneous incoming of plural ions with the same mass-to-charge ratio becomes appreciable. Thus a timer which can discriminate the height of a signal voltage generated by simultaneously incoming ions was introduced to find their correct number. The timer counted a larger number of high voltage signals for the major isotopes of W and Ni, 184W and 58Ni, than that expected from the natural abundance of these isotopes, indicating the high probability of simultaneous incomings. The number of the detected ions was corrected by weighing the number of the high voltage signals. The corrected abundance of W and Ni isotopes were found to be nearly equivalent to the natural abundances.
A 1K×1K high dynamic range CMOS image sensor with on-chip programmable region of interest readout (2001)

An integrated 1024×1024 CMOS image sensor with programmable region of interest (ROI) readout and multi-exposure technique has been developed and successfully tested. Size and position of the ROI is programmed based on multiples of a minimum readout kernel of 32×32 pixels. Since the dynamic range of the irradiance normally exceeds the electrical dynamic range of the imager that can be covered using a single integration time a multi exposure technique has been implemented in the imager. Subsequent sensor images are acquired using different integration times and recomputed to form a single composite image. A newly developed algorithm performing the recomputation is presented. The chip has been realized in a 0.5µm n-well standard CMOS process. The pixel pitch is 10µm × 10µm and the total chip area is 164mm2.
BOECK'S SARCOID OF THE STOMACH SIMULATING LINITUS PLASTICA (1954)

BOECK'S sarcoid frequently involves the lymph nodes and the lungs, but involvement of the stomach is rare. The case to be presented and the 12 others culled from the literature (Table) are of interest because in each instance symptomatology and barium studies mimicked gastric ulcer or carcinoma. Jessing,<sup>1</sup>in 1943, described the case of a 61-year-old white woman who suffered from epigastric pain, belching, and vomiting of three weeks' duration. An ulcer was seen on the lesser curvature in the barium study. This lesion persisted, and because a malignant tumor was feared, laparotomy with subtotal gastric resection was undertaken. An ulcer 2 cm. in diameter with an infiltrating rim was found. The gastric wall was greatly thickened, and the mucosa had a velvety appearance. In 1944, Gore and McCarthy<sup>2</sup>published their study of a 26-year-old man who complained of burning epigastric pain and eructation after meals. A cone-shaped
New Insight into the Role of Electron Transfer to O<sub>2</sub> in Photocatalytic Oxidations of Acetone over TiO<sub>2</sub> and the Effect of Au Cocatalyst (2019)

Photocatalytic oxidation by semiconductors is a dominant way to eliminate toxic organic pollutants. Different from thermal-activated catalysis, it is generally considered that the rate of charge carrier transfer from semiconductors to reactants determined photocatalytic activity. However, how charge carrier transfer correlates with photocatalytic activity is not well known, especially in gaseous photocatalytic oxidations of organics. By means of photoconductances, the present research gains some novel insight into the electron transfer in the acetone photocatalysis over TiO2. Because it is shown that the electron transfer from TiO2 to O2 is faster than the acetone conversion, our results point toward a fact that the electron transfer also contributes to the recombination via the O2 sorption cycling in addition to the photocatalytic effect. The role of Au for a cocatalyst was also investigated in the acetone photocatalysis. It is found that the decoration of TiO2 with Au nanoparticles indeed leads to an increase in the electron transfer from TiO2 to O2. Instead of a desirable increase, the photocatalytic rates however are decreased by Au decoration, independent on the methods to deposit Au, the Au nanoparticle size, and the Au amounts. The Au decoration also has no effect on the apparent activation energies of acetone conversion. These results lead to that the Au-induced increase in the electron transfer cannot contribute to the photocatalysis but can contribute to the recombination via the O2 sorption cycling. Therefore, it is possible that the photoinduced holes tend to accumulate around the Au/TiO2 perimeter and then recombine with the photoinduced electrons stored on Au at a faster rate, resulting in the decrease of photocatalytic activity. This research sheds some new light on the role of electron transfer in photocatalysis. The mere increase of the electron transfer could not promote the photocatalytic effect if the O2 sorption-assisted recombination is not inhibited; this should be helpful in designing highly-efficient photocatalysts.
A graph based algorithm for postures estimation based on accelerometers data (2010)

An algorithm is presented in this paper to estimate the activity of a person at each time index through a Bayesian approach. It does not require any pre-processing to identify single activity parts in the signal but can generate some instability in the estimated sequences of activities due to its nature. To circumvent this issue, the decision is enforced with a graph setting constraints between the different activities to be detected. As the method is based on a Bayesian approach, training can be used to adapt the algorithm to each person. If so, the algorithm shows very good performance.
Recognition and uptake of free and nanoparticle‐bound betalactoglobulin – a food allergen – by human monocytes (2011)

These results contribute to the current understanding of the interaction between food allergens and antigen-presenting cells, and demonstrate that the BLG is readily endocytosed by monocytes both as the single protein and as a conjugate.
Rich communication with audio-controlled network robot. Proposal of "Audio-MotionMedia" (2003)

To realize rich interactive communication, the concept of "Audio-MotionMedia" is proposed in this paper. This concept is based on the idea that robot control signals are embedded in an audio stream. In this concept, the audio signals play a role of a carrier to convey control signal. Two implementation methods of Audio-MotionMedia and two desktop type Audio-Motion communication robot systems are developed. These robot systems are applied to conventional communication media such as the World Wide Web and E-mail to realize enriched communication services. These services have been evaluated and favorably received.
Quantification of tear film thickness in healthy subjects using ultrahigh resolution OCT imaging (2012)

Abstract Purpose Dry eye syndrome is a highly prevalent disorder that can lead to severe visual impairment. A major challenge in the management of the disease is that signs and symptoms are poorly correlated. As such there is a major need for new innovative techniques to diagnose the disease. Methods We have realized a high‐resolution Fourier domain optical coherence tomography (OCT) system for the measurement of tear film thickness. As a light source we used a Ti:Sapphire laser with a bandwidth of more than 150 nm. A total of 26 healthy subjects were studied. Tear film imaging was started immediately after blinking and continued for 20 seconds thereafter. Results The tear film was on average 4.8 ± 0.9 µm and could be quantified in all subjects. Over the 20seconds time period no significant reduction in tear film thickness was observed. In some subjects, break‐up of the tear film could, however, be observed. The intra‐individual variability from frame‐to‐frame was low and typically below 10%. Conclusion Our data indicate that the human tear film thickness can be quantified using high‐resolution OCT. The technique may have considerable potential in the management of dry eye patients.
The effect of in vitro irradiation on mitogenic responsiveness of peripheral blood lymphocytes from untreated patients with hodgkin's disease and non-hodgkin's lymphoma (1982)

Blood lymphocytes from 20 untreated patients with Hodgkin's disease were compared with those of 20 untreated patients with non-Hodgkin's lymphoma with regard to the responsiveness of the cells to PHA and ConA following exposure to varying doses of ionizing radiation in vitro. Lymphocytes from 19 of the non-Hodgkin's lymphoma patients exhibited the same pattern of radiosensitivity as those of healthy donors, i.e., there was one relatively radiosensitive and one relatively resistant cell population. The latter cell population was undetectable in patients with Hodgkin's disease.
Rock-Around Orbits (2011)

A new class of orbits, called rock-around orbits, which are compatible to an assigned target orbit, is presented. These orbits allow the design of systems whose purpose is to explore and/or observe the space around an assigned target orbit. The proposed orbit design guarantees that, within a given repetition time, the whole space around the target orbit is observed under a prescribed maximum observation distance constraint. Potential applications can be civilian, to design orbits for mapping and monitoring systems, as well as military, to design orbits for space-based surveillance systems. This study shows how to design rock-around orbits for circular and elliptical target orbits, how to evaluate the observation efficiency, and how to estimate the orbit maintenance costs.
Concerted control of multiple histone promoter factors during cell density inhibition of proliferation in osteosarcoma cells: reciprocal regulation of cell cycle-controlled and bone-related genes. (1993)

Cell density-induced growth inhibition of osteosarcoma cells (ROS 17/2.8) results in the shutdown of proliferation-specific histone H4 and H2B genes and the concomitant up-regulation of several osteoblast-related genes. In several respects, this reciprocal regulatory relationship is analogous to the proliferation/differentiation transition stage during development of the bone cell phenotype in normal diploid osteoblasts. Here, we comprehensively analyzed the promoter binding activities interfacing with key regulatory elements in the cell cycle-dependent histone and bone-specific osteocalcin genes. Similarly, we examined factors interacting with a series of general transcription regulatory elements that are present in a broad spectrum of promoters. The results show that histone promoter binding activities HiNF-D, HiNF-P/H4TF-2, H4UA-1, and OCT-1, as well as AP-1 activity, are proliferation dependent. These factors decline coordinately during the cessation of proliferation in both ROS 17/2.8 bone tumor cells and normal diploid osteoblasts. Collective down-regulation of these trans-activating factors occurs in both cell types within the physiological context of constitutive regulation of ubiquitous transcription factors (Sp1, ATF, and CCAAT binding proteins). In addition, during growth inhibition of ROS 17/2.8 cells we observe a complex series of modifications in protein/DNA interactions of the osteocalcin gene. These modifications include both increased and decreased representation of promoter factor complexes occurring at steroid hormone response elements as well as tissue-specific basal promoter sequences. These results demonstrate cell growth regulation of the promoter factors binding to the proliferation-specific histone and tissue-specific osteocalcin genes during the cessation of proliferation.
<title>Homogeneous linewidths in Er<formula><sup><roman>3+</roman></sup></formula>-doped glasses measured by resonance fluorescence line narrowing</title> (1992)

Resonance-fluorescence-line-narrowing studies have been performed on a representative group of Er3+ -doped glasses for excitation in both the 1530 and 980-nm bands at 4.2, 77, 200, and 300 K. Fluorozirconate, fluorophosphate, phosphate, silicate, Ge/P-doped and A1/P-doped silica preforms, and Al/P-doped and Ge-doped fibers were examined. At 77 K the homogeneous linewidths were found to be relatively insensitive to composition. In particular, they vary from 1.4 to 1.8 cm-1 for the different hosts using excitation at 1531 nm. At 300 K weak resonant features were observed in most samples, consistent with a small inhomogeneous contribution to a predominantly homogeneous fluorescence emission.