gebhart/patrepeval huggingface dataset:
Electrical conduction and field emission of a single-crystalline GdB<sub>44</sub>Si<sub>2</sub> nanowire (2020)

The electronic transport and field emission properties of a single-crystalline GdB44Si2 nanowire are studied. The atomic structure and elemental composition of the GdB44Si2 nanowire are characterized by transmission electron microscopy (TEM) using atomic imaging, energy-dispersive X-ray spectroscopy (EDS), and electron energy-loss spectroscopic (EELS) mapping. The electrical conductivity of the single GdB44Si2 nanowire is in the range of 46.8-60.1 S m-1. The in situ TEM field emission measurement reveals that it has a low work function of 2.4 eV. To realize a converged electron emission, a field evaporation pretreatment was used to clean the emission surface and to make a sharpened tip. The field emission probe measurement results show that the electron emission from the sharp GdB44Si2 nanowire is converged to a single field emission spot and it has a work function of 2.6 eV which is in agreement with the in situ TEM measurement. The stability of field emission current is also very good with a fluctuation of 1.4% in 20 min. With a low work function and stable emission current, the GdB44Si2 nanowire shows great promise for field emission applications.
Abstract 1865: Simultaneous de-repression of innate and adaptive immune responses through dual targeting of ILT4 and PD(L)-1 with bispecific antibodies (2021)

Abstract Activation of innate immunity using targeted therapies has become an attractive approach to stimulate antitumor responses. Dual inhibition of receptors that suppress myeloid and T cell compartments through the generation of bispecific antibodies (bsAbs) is a promising strategy to overcome resistance to checkpoint inhibition. Activation of the ITIM-bearing ILT4/LILRB2 receptor by its cognate ligands (HLA-G and HLA Class I) in myeloid cells induces a strong immunosuppressive response that may be leveraged by tumors to evade immune surveillance. Monoclonal antibodies (mAbs) that inhibit ILT4 activity have demonstrated promising preclinical and early clinical data in combination with PD-1 inhibitors, including in the checkpoint refractory setting. These findings provide a rationale to co-target ILT4 with PD(L)-1 using a single molecule. We describe the discovery and characterization of ILT4 inhibitory mAbs for engineering bsAbs that revert myeloid cell suppression by antagonizing ILT4 and activate T cell responses through PD(L)-1 inhibition. Humanized anti-ILT4 mAbs were generated that specifically bind human and macaque ILT4. These mAbs exhibit sub-nanomolar HLA-G binding to ILT4 expressing cells. Macrophages treated with ILT4 mAbs release inflammatory cytokines/chemokines and upregulate activation markers resulting in polarization to an M1 inflammatory phenotype. These activities are further potentiated in the presence of toll-like receptor activation with lipopolysaccharide (LPS). We engineered tetravalent bsAbs using an Fc-silenced IgG1 linked to scFv format from our anti-ILT4 and anti-PD-L1 mAbs in both orientations. The bsAbs have good biophysical characteristics and retain functional properties similar to the parental mAbs. Further in vitro and in vivo characterization efforts are ongoing to select the bsAb candidate to enter development activities and IND-enabling studies. Citation Format: Laura Vitale, Mike Murphy, Jeff Weidlick, Anna Wasiuk, Thomas O'Neill, Jenifer Widger, Laura Mills-Chen, Andrea Crocker, Colleen Patterson, James Boyer, Linda Crew, Edward J. Natoli, Jay S. Lillquist, Joel Goldstein, Lawrence J. Thomas, Henry C. Marsh, Diego Alvarado, Tibor Keler. Simultaneous de-repression of innate and adaptive immune responses through dual targeting of ILT4 and PD(L)-1 with bispecific antibodies [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2021; 2021 Apr 10-15 and May 17-21. Philadelphia (PA): AACR; Cancer Res 2021;81(13_Suppl):Abstract nr 1865.
Antitumor activity of anti-CD30 immunotoxin (Ber-H2/saporin) in vitro and in severe combined immunodeficiency disease mice xenografted with human CD30+ anaplastic large-cell lymphoma (1995)

To develop a novel adjunctive therapy for CD30 (Ki-1)+ anaplastic large-cell lymphoma (ALCL), we investigated in preclinical studies the antitumor activity of an immunotoxin (IT) constructed by coupling the plant ribosome-inactivating protein saporin (SO6) to the monoclonal antibody (MoAb) Ber-H2 that is directed against the CD30 molecule, a new member of the tumor necrosis factor receptor (TNFR) super-family. The activity of Ber-H2/SO6 IT was tested both in vitro against the CD30+ ALCL-derived cell line JB6 and in vivo using our severe combined immunodeficiency disease (SCID) mouse model of human xenografted CD30+ ALCL. In vitro, the Ber-H2/SO6 IT was selectively and highly toxic to the JB6 cell line [50% inhibiting concentration (IC50), 3.23 x 10(-12) mol/L as SO6]. In vivo, a 3-day treatment with nontoxic doses of Ber-H2/SO6 (50% of LD50) induced lasting complete remissions (CR) in 80% of mice when started 24 hours after tumor transplantation. In contrast, injection of the IT at later stages of tumor growth (mice bearing subcutaneous tumors of 40- to 60-mm3 volume), induced CR in only 6 of 21 (approximately 30%) mice and significantly delayed tumor growth rate (P < .01). This finding suggests that maximum effect of the anti-CD30 IT is observed when tumor cell burden is small. Persistent tumors from IT-treated mice consisted of CD30+ cells, thus excluding the possibility that selection of CD30-negative mutant clones during IT therapy was responsible for resistance to treatment. We conclude that Ber-H2/SO6 IT is an effective agent against CD30+ ALCL growing in SCID mice, suggesting its possible role as adjuvant therapy in patients with CD30+ ALCL refractory to standard treatments.
<title>An Opto-Electronic Alternative to Programmable Digital Time-Delay Functions in High Resolution Synthetic-Aperture Ultrasound Equipment</title> (1976)

In the synthetic-aperture method of acoustical imaging, reflections are processed to achieve resolution improvements expected from transducers larger than commonly used in diagnostic ultrasonography. Since in practice transducers cannot exceed about 3 cm in diameter, electronic aperturing simulates a larger transducer with increased azimuthal resolution. All depths in the field of view are equally in focus, eliminating beam divergence. This inexpensive system functions in real time, providing immediately displayed high-resolution B-scans. A single-channel transducer is rapidly driven by novel mechanical means achieving high frame rates and high transducer position densities without costs and complexities of transducer arrays. Data acquisition, processing, and display occur on line, eliminating much memory storage and programmable time-delay functions typical of synthetic aperture systems. Novel optical-electronic computational methods are utilized. Range and azimuthal resolutions of stationary and moving phantoms are compared for identical insonifying frequencies against conventional diagnostic B-scanners.
Two-Dimensional Modeling of Aluminum-Ion Implantation into 4H-SiC (2011)

A two-dimensional model of aluminum-ion implantation into 4H-SiC at moderate doses (1011 to 1013 cm-2) has been developed. The model is based on a Monte-Carlo simulation using a binary-collision approximation. This simulation reveals that iso-concentration contours are independent of the orientation of the masking edge. Lateral range straggling is extracted by expressing the lateral-concentration profiles as a one-dimensional dual-Pearson-distribution function multiplied by a Gauss-distribution function. Compared to vertical straggling, the lateral straggling is found to be more weakly dependent on projected range.
General Networks for Central Terminals in Electrocardiography and Vectorcardiography (1955)

A method is described for obtaining true orthogonal components of the heart vector by measuring the differences in potential between resistor networks which are connected to the limbs and to the back. The values of the resistors in the networks are determined by solving equations into which the scalar coefficients for the limbs and for the back are inserted.
Pathologic findings in dogs infected with newly emerged canine H3N8 influenza virus (2006)

In 2004, investigation of an outbreak of a spontaneous respiratory disease in greyhound dogs in Jacksonville FL led to the isolation of an H3N8 influenza A virus (canine/FL/04). Gene sequence analysis indicates the virus was of equine origin. Subsequent respiratory disease investigation studies have demonstrated that closely related H3N8 canine influenza virus has become widely disseminated throughout the United States and is inducing serious respiratory disease both in racing greyhound dogs and in pet and animal shelter dog populations. Postmortem examinations were conducted on greyhound dogs in the initial disease outbreak and subsequently in pet and animal shelter dogs of varying breeds that were demonstrated to be canine influenza positive by RT‐PCR and/or virus isolation. In addition, dogs were inoculated intratracheally with canine/FL/04 virus and studied at 5 and 14 days after inoculation. In all dogs studied, canine influenza virus infection was associated with severe erosive or hyperplastic tracheitis and bronchitis. Viral antigen was identified in epithelial cells lining trachea, bronchi and their glands and in macrophages. Budding virions were identified by transmission electron microscopy on the apical surface of bronchial ciliated epithelial cells in association with severe ciliary defects. In greyhound dogs, death following infection was associated with severe hemorrhagic pneumonia and hemorrhage throughout thoracic tissues. In spontaneous canine influenza infections, secondary bacterial pneumonia was common. Funded by State of Florida Pari‐mutuel Trust Fundt
Studies on Anti-inflammatory Agents. IV. Anti-inflammatory Constituents from Roots of Panax ginseng C.A. MEYER (1981)

The Ginseng Radix (ginseng root) is prescribed in many Chinese medicines as a stomachic and for the purpose of antidiarrhoic effect, metabolic promotion, and hematic effects, and has been well known as one of the representative drugs of nutritious tonics. In a continuing scientific search for Chinese medicines, we tried systematic extraction of some Chinese medicines, and checked activity of each fraction by means of the fertile egg method, and found a strong inhibitory activity against the formation of granulation tissue in the chloroform extract. The detailed investigation of this extract resulted in the isolation of panaxynol (1) and linoleic acid (2), which were proved to be major active components.
Modeling and Simulation of Parameter Vector Random Processes in Mechanical Structures (2012)

The objective of this paper is to present a framework for modeling and simulation of parameter vector random processes. While the approach described in the paper can be applied generally, we are interested in problems where there is a limited set of random process data (e.g., FRFs or IRFs) for which the dominant sources of randomness (i.e., the dominant random parameters) are not known a-priori. From this limited set of random process data we aim to create a framework for estimating the underlying distribution to enable simulation and analysis of the family of systems from which the original data set came. The approach recommended for modeling random parameter vectors for physical systems is the Karhunen-Loeve expansion. Our innovation is to use additional knowledge (constraints) about the system that spawned the random process in a screening that classifies the synthetic realizations as plausible or implausible and yields a more representative data set.
A 24 GHz Low-power and High-gain Low-noise Amplifier Using 0.18 mu m CMOS Technology for FMCW Radar Applications (2012)

In this paper, a low power and high gain low-noise amplifler (LNA) is presented for 24GHz FMCW radar applications fabricated in a 0.18m RF CMOS process. The proposed LNA is with the characteristics of the source inductive degeneration type, the current reuse technique, and the invariance of current density in CMOS process. The proposed LNA with a compact size has a gain of 18.95dB and a noise flgure of 5.8dB, while consuming 11.3mW. The measured input 1-dB compression point (IP1dB) and an input third-order intercept point (IIP3) are i26dBm and i16:5dBm, respectively.
Environment-friendly swine feed formulation to reduce nitrogen and phosphorus excretion (1993)

Abstract The nutrient composition of swine excreta can be altered by manipulating the composition of the pig's diet Several approaches are reviewed: feeding according to the pig's growth phase, formulation according to the feed's digestible amino acids, use of crystalline amino acids, the ideal protein approach, formulation according to available phosphorus, and the addition ofphytase enzymes. Each has the potential to lower nitrogen or phosphorus excretion levels. Together they can dramatically reduce the nitrogen and phosphorus concentration of swine manure, which could be a major advantage in regions with a high density of swine or for swine operations with limited access to arable land. However, the value of the swine manure would be much less as a fertilizer because these two elements are important plant nutrients.
Role of excitation-induced shift in the coherent optical response of semiconductors (2002)

A transient four-wave-mixing signal is shown to arise from an excitation induced shift. In semiconductors, this signal can be comparable to or stronger than signals arising from saturation, local fields, or excitation induced dephasing. Calculations using modified optical Bloch equations show that multiple peaks in the transient four-wave-mixing spectrum are a signature of an excitation induced shift contributing to the signal. We observe this experimentally from a semiconductor multiple quantum well and confirm the presence of a shift directly using spectrally resolved differential transmission.
Diels−Alder Reaction of Heterocyclic Imine Dienophiles (2000)

ADVERTISEMENT RETURN TO ISSUEPREVNoteNEXTDiels−Alder Reaction of Heterocyclic Imine DienophilesChristian Hedberg, Pedro Pinho, Peter Roth, and Pher G. AnderssonView Author Information Department of Organic Chemistry, Uppsala University, Box 531, S-75121 Uppsala, Sweden Cite this: J. Org. Chem. 2000, 65, 9, 2810–2812Publication Date (Web):April 13, 2000Publication History Received25 October 1999Published online13 April 2000Published inissue 1 May 2000https://pubs.acs.org/doi/10.1021/jo9916683https://doi.org/10.1021/jo9916683brief-reportACS PublicationsCopyright © 2000 American Chemical SocietyRequest reuse permissionsArticle Views1145Altmetric-Citations33LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Addition reactions,Aldehydes,Cyclization,Ligands,Nitrogen Get e-Alerts
Studies on Fluid-Structural Coupling for Aerothermoelasticity in Hypersonic Flow (2009)

The field of aerothermoelasticity plays an important role in the analysis and optimization of airbreathing hypersonic vehicles, impacting the design of the aerodynamic, structural, control, and propulsion systems at both the component and multidisciplinary levels. This study aims to expand the fundamental understanding of hypersonic aerothermoelasticity by performing systematic investigations into fluid-thermal-structural coupling. A focus is on the targeted use of simplified coupling procedures in order to abate the computational effort associated with comprehensive aerothermoelastic analysis. Because of the fundamental nature of this work, the analysis is limited to cylindrical bending of a simply supported, von Karman panel. Multiple important effects are included in the analysis: namely, 1) mutual coupling between elastic deformation and aerodynamic heating, 2) transient arbitrary in-plane and through-thickness temperature distributions, and 3) the associated thermal stresses and material property degradations. It is found that including elastic deformations in the aerodynamic heating computations results in nonuniform heat flux, which produces nonuniform temperature distributions and material property degradations. This results in localized regions in which material temperature limits may be exceeded; it also impacts flutter boundary predictions and nonlinear flutter response. Additionally, the tradeoff between computational cost and accuracy is evaluated for aerothermoelastic analysis based on either quasi-static or time-averaged dynamic coupling. It is determined that these approaches offer substantial reductions in computational expense, with negligible loss of accuracy, for aerothermoelastic analysis over long-duration hypersonic trajectories.
PREFACE (1977)

ADVERTISEMENT RETURN TO BOOKPREVPrefaceNEXTPREFACELYLE F. ALBRIGHTLYLE F. ALBRIGHTWest Lafayette, Indiana June 1977More by LYLE F. ALBRIGHT and ARTHUR R. GOLDSBYARTHUR R. GOLDSBYChappaqua, New YorkMore by ARTHUR R. GOLDSBYDOI: 10.1021/bk-1977-0055.pr001 This publication is free to access through this site. Learn MorePublication Date (Print):June 1, 1977Publication History Published online23 July 2009Published inprint 1 June 1977Request reuse permissions Copyright © 1977 AMERICAN CHEMICAL SOCIETY. This publication is available under these Terms of Use. Industrial and Laboratory Alkylationspp ix-xACS Symposium SeriesVol. 55ISBN13: 9780841203853eISBN: 9780841204423Chapter Views94Citations-LEARN ABOUT THESE METRICSChapter Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail PDF (279 KB) Get e-Alerts
Ion drag and plasma-induced thermophoresis on particles in radiofrequency glow discharges (1994)

A comparison is made of the forces governing the transport of negatively charged particles electrostatically suspended in the plasma of a symmetric parallel-plate radiofrequency glow discharge with isothermal walls. The two forces driving the particles symmetrically from the plasma centreline to the sheath edges are the ion drag force and the plasma-induced thermophoresis due to the thermal gradient appearing in the gas heated by plasma power dissipation. A general expression of the ion drag force as a function of the ratio of the ion drift velocity and thermal velocity is obtained by a proper integration over the ion energy distribution using the analytical expression for the ion orbital momentum transfer cross section derived by Kilgore et al. (J. Appl. Phys. 73 7195 (1993)). The ion drag force is then compared with the plasma-induced thermophoresis on submicrometre-size particles in well-characterized experimental discharge conditions in Ar. It appears that ion drag is usually larger than thermophoresis on an isolated particle in a pristine discharge. However, thermophoresis always dominates over ion drag in dusty discharges where plasma-particle and particle-particle interactions result in a drastic reduction of the ion drift velocity through the plasma bulk.
TextSETTR: Few-Shot Text Style Extraction and Tunable Targeted Restyling (2021)

Parker Riley, Noah Constant, Mandy Guo, Girish Kumar, David Uthus, Zarana Parekh. Proceedings of the 59th Annual Meeting of the Association for Computational Linguistics and the 11th International Joint Conference on Natural Language Processing (Volume 1: Long Papers). 2021.
Signal Reconstruction From Fourier Transform Amplitude* (1983)

In a variety of contexts, it is desirable to reconstruct a sequence from partial Fourier domain information. As a consequence, considerable attention has been paid to, and some significant results have been developed in, this area. For example, it has been established [1,2] that under very mild restrictions a finite extent one-dimensional (1-D) or multi-dimensional (M-D) sequence is uniquely specified to within a scale factor by its Fourier transform (FT) phase, and algorithms for implementing the reconstruction have been developed. It is well known that in contrast, the FT magnitude does not uniquely specify a 1-D sequence. Even for M-D sequences, the FT magnitude specifies a sequence only to within a translation and a central symmetry [2], and reconstruction algorithms developed so far have been successful [2] for only a very restricted class of M-D sequences.
Piezoresistive detection-based ferromagnetic resonance force microscopy of microfabricated exchange bias systems (2004)

Ferromagnetic resonance measurements were performed on CoO∕Co exchange biased microstructures with a low-temperature magnetic resonance force microscope (MRFM). The MRFM instrument relies on piezoresistive force detection, and the magnetic tip attached to the cantilever acts as a field gradient source. These features extend the applicability of the MRFM that can also be used as a conventional magnetic force microscope. Spatial variations of the MRFM signal, which are induced by a spatially modulated exchange bias, are monitored with a lateral resolution of about 5μm.
The chelation of metal ions by dipeptides and related substances. Part 2.—Cupric complexes (1956)

S. P. Datta and B. R. Rabin, Trans. Faraday Soc., 1956, 52, 1123 DOI: 10.1039/TF9565201123