gebhart/patrepeval huggingface dataset:
Effect of Flow Direction for the Heat Transfer Performance of Refrigerant R-410A Evaporation in a Plate Heat Exchanger (2013)

This article provides an experimental investigation of the effect of flow direction for refrigerant R-410A evaporated in a plate heat exchanger. Parallel-flow and counterflow arrangements with 2°C and 5°C exit superheat conditions were tested. The refrigerant entered the test section at a vapor quality of 0.24 and evaporated at a saturation temperature of 1.1°C. The experimental results were analyzed by the evaporation heat transfer coefficient and overall average heat transfer coefficient separately. The evaporation heat transfer coefficient in parallel-flow arrangement is higher than that in the case of counterflow arrangement. However, the average heat transfer coefficients are affected not only by the flow direction, but also by the exit superheat condition. The interaction of these two effects causes there to be almost no difference of the average heat transfer performance between these two flow arrangements for low exit superheat condition. While the refrigerant exit superheat is high, the overall heat transfer performance of the parallel-flow case is lower than that of the counterflow case.
Construction of the Voronoi diagram for 'one million' generators in single-precision arithmetic (1992)

A numerically stable algorithm for constructing Voronoi diagrams in the plane is presented. In this algorithm higher priority is placed on the topological structure than on numerical values, so that, however large the numerical errors, the algorithm will never come across topological inconsistency and thus can always complete its task. The behavior of the algorithm is shown with examples, including one for as many as 10/sup 6/ generators.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
<i>In Vitro, Ex Vivo</i> , and <i>In Vivo</i> Methodological Approaches for Studying Therapeutic Targets of Osteoporosis and Degenerative Joint Diseases: How Biomarkers Can Assist? (2005)

Although our approach to the clinical management of osteoporosis (OP) and degenerative joint diseases (DJD)-major causes of disability and morbidity in the elderly-has greatly advanced in the past decades, curative treatments that could bring ultimate solutions have yet to be found or developed. Effective and timely development of candidate drugs is a critical function of the availability of sensitive and accurate methodological arsenal enabling the recognition and quantification of pharmacodynamic effects. The established concept that both OP and DJD arise from an imbalance in processes of tissue formation and degradation draws attention to need of establishing in vitro, ex vivo, and in vivo experimental settings, which allow obtaining insights into the mechanisms driving increased bone and cartilage degradation at cellular, organ, and organism levels. When addressing changes in bone or cartilage turnover at the organ or organism level, monitoring tools adequately reflecting the outcome of tissue homeostasis become particularly critical. In this context, bioassays targeting the quantification of various degradation and formation products of bone and cartilage matrix elements represent a useful approach. In this review, a comprehensive overview of widely used and recently established in vitro, ex vivo, and in vivo set-ups is provided, which in many cases effectively take advantage of the potentials of biomarkers. In addition to describing and discussing the advantages and limitations of each assay and their methods of evaluation, we added experimental and clinical data illustrating the utility of biomarkers for these methodological approaches.
AlGaAs/GaAs transverse junction stripe lasers with distributed feedback (1981)

Transverse junction stripe (TJS) lasers with periodic feedback were fabricated in two geometries. An interferometric and wet chemical etching technique was used to create a feedback grating across the entire pumping region for the distributed feedback (DFB) TJS laser and to create the separate distributed Bragg reflectors/DBR) for the TJS/DBR laser. The TJS/DFB laser was a double heterostructure device grown by liquid phase epitaxy (LPE) and had a third order grating etched in the top ALO.2GaO.8As layer. The grating was buried by growing an ALO.35GaO.65As layer on the grating by metal organic chemical vapor deposition (MO-CVD). The TJS/DBR laser was also fabricated in an LPE double heterostructure. The top AlGaAs layer was thinned to 0.1 micron over more than half of the laser so that the grating would be close to the GaAs active layer and optical field. Single mode operation in both configurations was obtained. The thermal shift of the laser wavelength in both cases was less than 1 Angstrom/deg K, compared to the 3 Angstrom/deg K shift of the spontaneous emission peak.
Microstructure and Properties of Plasma Spray Coatings Prepared from Ti-Zr-Ni Quasicrystalline Powders (2007)

This DOI is not currently attached to any metadata records. DOIs can’t actually ever be deleted (they’re persistent), but sometimes our members create DOIs in error. We do have a process to approximate deletion which we follow only in rare cases where the DOI has been genuinely created in error, and most crucially, if the DOI has never been published anywhere online or in print and never otherwise distributed to or communicated with anyone (authors, readers, reviewers, etc.
Proactive event processing in action (2013)

Proactive event processing constitutes the next phase in the evolution of complex event processing. Proactive event processing makes it possible to anticipate potential issues during process execution and thereby enables proactive process management. One industry domain that can expect relevant benefits from applying proactive event processing is transportation. Transportation companies face numerous stochastic issues when managing the shipment of goods. One such issue faced in airfreight is the exact volume, weight, and number of pieces that a shipper wants to have shipped. Because of the high cost of air shipments, discrepancies between what has been booked by a shipper and the actual volume that is delivered impose costs that create problems for all participants in a shipment. One potential approach to addressing this problem is to use real-time monitoring and proactive alerting to assist air freight companies in anticipating actual delivered weights, volumes, and piece counts. In this paper we address the issue of cargo shipments by leveraging real-time monitoring data collected from an industry-standard monitoring system of a large freight forwarding company. Our evidence indicates that by using a novel proactive event-driven software engine, prediction about the weight of shipments can be developed and used in a proactive manner to assist air freight planners in making better estimates and plans for the shipment of goods. We demonstrate that through the use of this proactive approach, predictions concerning over and under-weight loads can be made days in advance of a shipment, thus enabling the air freight planner to optimize their load plans and thus maximize the revenue that they generate from shipments.
Structurally modified antitumour agents. Synthesis of a cyclopropamitosene (1989)

G. B. Jones and C. J. Moody, J. Chem. Soc., Chem. Commun., 1989, 186 DOI: 10.1039/C39890000186
Transduction of large optomechanical amplitudes with racetrack-loaded Mach-Zehnder interferometers (2020)

Chip-integrated photonic devices have stimulated development in areas ranging from telecommunications to optomechanics. Racetrack resonators have gained popularity for optomechanical transduction due to their high sensitivity and cavity finesse. However, they lack sufficient dynamic range to read out large amplitude mechanical resonators, which are preferred for sensing applications. We present a robust photonic circuit based on a Mach-Zehnder interferometer (MZI) combined with a racetrack resonator that increases linear range without compromising high transduction sensitivity. Optical and mechanical properties of combined MZI-racetrack devices are compared to lone racetracks with the same physical dimensions in the undercoupled, overcoupled and critical coupled regimes. We demonstrate an overall improvement in dynamic range, transduction responsivity, and mass sensitivity of up to 4x, 3x and 2.8x, respectively. Our highly phase sensitive MZI circuit also enables applications such as on-chip optical homodyning.
Multiphase hydrodynamics of free and confined thin films with fluid-structural interactions. (2011)

Abstract not provided.
Improved Sensitivity of DNA Microarrays Using Photonic Crystal Enhanced Fluorescence (2010)

DNA microarrays are used to profile changes in gene expression between samples in a high-throughput manner, but measurements of genes with low expression levels can be problematic with standard microarray substrates. In this work, we expand the detection capabilities of a standard microarray experiment using a photonic crystal (PC) surface that enhances fluorescence observed from microarray spots. This PC is inexpensively and uniformly fabricated using a nanoreplica molding technique, with very little variation in its optical properties within- and between-devices. By using standard protocols to process glass microarray substrates in parallel with PCs, we evaluated the impact of this substrate on a one-color microarray experiment comparing gene expression in two developmental stages of Glycine max. The PCs enhanced the signal-to-noise ratio observed from microarray spots by 1 order of magnitude, significantly increasing the number of genes detected above substrate fluorescence noise. PC substrates more than double the number of genes classified as differentially expressed, detecting changes in expression even for low expression genes. This approach increases the dynamic range of a surface-bound fluorescence-based assay to reliably quantify small quantities of DNA that would be impossible with standard substrates.
A proteome study of the proliferation of cultured <b><i>Medicago truncatula</i></b> protoplasts (2007)

A proteome study of the first five days of Medicago truncatula protoplast cultures was done to investigate molecular changes taking place during protoplast proliferation. A total of 1556 protein spots were analysed, of which 886 protein spots showed significant (p<0.005) changes in abundance at some time during the first five days of protoplast culture. Of the 886 significantly changing protein spots, 89 proteins were identified by MALDI-TOF MS. The majority of the identified proteins were part of four main cellular processes that may be involved in protoplast proliferation: energy metabolism, defence or stress response, secondary metabolism and protein synthesis and folding. The accumulation pattern of these proteins indicates extensive changes in the energy metabolism of the cells, accompanied by the activation of stress response pathways and modifications of the cell wall. In addition, seven PR10-like (pathogenesis related) proteins were identified. The accumulation pattern of these seven PR10-like proteins suggests that they could have a developmental role during protoplast proliferation.
Protocol management in computer networking (2000)

From the Publisher:
Taking an innovative approach to network management, communications protocols, and data networks, this new book examines a unique method in which protocols and mechanisms are broken down into simple management tasks. It helps you steer your way through the history of network management and communications protocols, and guides you through the design of new protocols and the construction of complex networks operating under a simpler paradigm.

Using a new vocabulary to discuss tasks and mechanisms of data communications, the book eliminates the distinction between protocols and management, as well as the distinctions made in phases throughout a network's lifecycle. Here you will find a new model for network management wherein various data communications protocols and mechanisms are easily handled as basic management tasks, thereby reducing expenditures of time, effort, and resources.

Using a bottom-up approach and avoiding rigorous mathematical devices, this book applies a new network control theory to all the layers you encounter in network planning, design, and management.
A Limited Objective Experiment on Wireless Peer-To-Peer Collaborative Networking (2002)

The implications of using peer-to-peer communications within an urban environment are significant for military applications. From a networking perspective, the use of wireless technologies to support collaborative communications may have impacts on bandwidth and spectrum utilization. This paper explores the effects of wireless peer-to-peer (P2P) network behavior on the performance of collaboration support applications. The results achieved during the limited objective experiment conducted by the Naval Postgraduate School demonstrate significant effects of roaming on application-sharing performance and integration with client-server applications. The authors discuss the wireless network operation challenges leading to the solutions for scaling up application-sharing and improving collaborators' self-organizing behavior.
Effects of Reactive Compensation on Induction Motor Dynamic Performance (1980)

Induction motors are known to cause voltage dip, inrush current, and a low lagging power factor in the distribution network. To compensate for these effects shunt capacitor banks are generally used. Recently, however, an increasing number of utility operation departments are reporting increased occurrence of poor motor performance and excessive voltage dips during starting and running although they properly used shunt capacitor banks. The use of series capacitor banks appears to be helpful in some cases, while erratic and unexplained motor behaviour occurs in other cases.
Measurement of laser-induced Compton backscattered photons with anti-Compton spectrometer (1991)

Quasi-monochromatic photons of energies of 1.6-8.7 MeV have been generated by the Compton backscattering of laser light on relativistic electrons in the TERAS storage ring. The spectra of the backscattered photons have been measured with an anti-Compton spectrometer system. The present system has a 155-cm/sup 3/ a coaxial-type pure-Ge detector as the central detector and a well-type NaI(Tl) scintillator of 8-in phi *8-in as the outer one. With a usual anticoincidence technique, clear photopeak spectra were obtained with a Compton suppression ratio of 2-4. The maximum energy and the energy spread of photons show reasonable agreement with numerical calculations. The divergence and energy spread of the electron beam in the storage ring are estimated from the data.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
ChemInform Abstract: Synthesis of 4‐Highly‐Branched Imidazole Derivatives via Cine‐Substitution and SRN1 Substitution of 5‐Nitroimidazoles with Anions of Nitroalkanes. (1989)

Abstract The anion of 2‐nitropropane (II) reacts with the nitroimidazole (I) to yield the nitroalkylimidazole (III) as the main product.
Efficacy and safety of bleselumab in kidney transplant recipients: A phase 2, randomized, open-label, noninferiority study (2019)

This study assessed the efficacy and safety of the anti-CD40 monoclonal antibody bleselumab (ASKP1240) in de novo kidney transplant recipients over 36 months posttransplant. Transplant recipients were randomized (1:1:1) to standard of care (SoC: 0.1 mg/kg per day immediate-release tacrolimus [IR-TAC]; target minimum blood concentration [C<sub>trough</sub> ] 4-11 ng/mL plus 1 g mycophenolate mofetil [MMF] twice daily) or bleselumab (200 mg on days 0/7/14/28/42/56/70/90, and monthly thereafter) plus either MMF or IR-TAC (0.1 mg/kg per day; target C<sub>trough</sub> 4-11 ng/mL days 0-30, then 2-5 ng/mL). All received basiliximab induction (20 mg pretransplant and on days 3-5 posttransplant) and corticosteroids. One hundred thirty-eight transplant recipients received ≥1 dose of study drug (SoC [n = 48]; bleselumab + MMF [n = 46]; bleselumab + IR-TAC [n = 44]). For the primary endpoint (incidence of biopsy-proven acute rejection [BPAR] at 6 months), bleselumab + IR-TAC was noninferior to SoC (difference 2.8%; 95% confidence interval [CI] -8.1% to 13.8%), and bleselumab + MMF did not demonstrate noninferiority to SoC (difference 30.7%; 95% CI 15.2%-46.2%). BPAR incidence slightly increased through month 36 in all groups, with bleselumab + IR-TAC continuing to demonstrate noninferiority to SoC. Bleselumab had a favorable benefit-risk ratio. Most treatment-emergent adverse events were as expected for kidney transplant recipients (ClinicalTrials.gov NCT01780844).
Molecular Basis of Binding Interactions of NSAIDs and Computer-Aided Drug Design Approaches in the Pursuit of the Development of Cyclooxygenase-2 (COX-2) Selective Inhibitors (2017)

The nonsteroidal anti-inflammatory drugs (NSAIDs) are important class of therapeutic agents used for the treatment of pain, inflammation and fever. Nonselective inhibition of cyclooxygenase (COX-1 and COX-2) isoenzymes by classical NSAIDs is associated with undesirable side effects such as gastrointestinal (GI) and renal toxicities due to COX-1 inhibition. To circumvent this problem, several COX-2 selective inhibitors were developed with superior GI safety profile. However, the voluntary market withdrawal of potent COX-2 selective inhibitors (rofecoxib and valdecoxib) due to their severe cardiovascular toxicity which is also found to be associated with some of the traditional NSAIDs suggesting the need to relook into the entire class of NSAIDs rather than exclusively victimizing the COX-2 selective inhibitors. Furthermore, the recent evidences for the involvement of COX-2 selective inhibitors in the aetiology of many diseases, such as Alzheimer’s disease, Parkinson’s disease, diabetes, various cancers and so on, have gained much attention for researchers to design and develop novel COX-2 selective inhibitors with improved pharmacodynamics and pharmacokinetic profile. This chapter is focused on the detailed analysis of molecular basis of binding interactions of various NSAIDs by highlighting the role of crucial amino acid residues at the binding site of cyclooxygenase enzymes (COXs) to be considered for selective inhibition of COX-2 enzyme while emphasising the impact of significant CADD strategies employed for designing new potent COX-2 inhibitors with tuned selectivity.
Confronto tra metodi di misura delle tensioni residue su un disco estratto da un cilindro autoforzato (2018)

La presente memoria analizza i risultati di misure di Tensioni Residue (TR) effettuate su un disco estratto da un cilindro autoforzato eseguite mediante tre tecniche: il metodo della deformazione iniziale (ISD), il metodo del foro cieco (BHD) e il metodo dei raggi X (XRD). Data la geometria e la natura del trattamento di autoforzamento, il campione esaminato presenta un campo di tensioni residue assialsimmetrico che varia solo con la coordinata radiale. Questo permette di confrontare direttamente le tre tecniche di misura che, a tale scopo, sono state applicate in sequenza su diverse aree dello stesso disco. Le tensioni residue ottenute dalle le tre tecniche di misura, vengono presentate e confrontate. In aggiunta vengono tratte alcune conclusioni sulla validità del metodo dell’ISD.
Pohlman Edward H. — The Psychology of Birth Planning (1973)

Hecht Jacqueline. Pohlman Edward H. — The Psychology of Birth Planning. In: Population, 28ᵉ année, n°2, 1973. pp. 432-433.
Nitric oxide does not mediate but inhibits transformation and tumor phenotype. (2003)

(a) induction of iNOS and NO production does not mediate but actually prevents tumor promotion; (b) iNOS inhibitors enhance the transformation response, and therefore appear not to be appropriate as chemoprevention agents; and (c) NO has both chemopreventive and tumoricidal effects, suggesting promise in cancer chemoprevention and therapy.
ChemInform Abstract: Studies on Bioactive Compounds. Part 13. Synthesis and Lack of Growth‐Inhibitory Properties of Cyclohexane‐1,2,4‐triol 1,2‐Diesters, Which Resemble Ring C of the Phorbol Ester Molecule. (1989)

Abstract The cyclohexenol (I) is protected by reaction with the chlorosilane (II) to form the siloxycyclohexene (III).
Relationships of Sweet, Bitter, and Roasted Peanut Sensory Attributes with Carbohydrate Components in Peanuts (2000)

Certain roasted peanut quality sensory attributes have been shown to be heritable. Currently the only means of measuring these traits is the use of a trained sensory panel. This is a costly and time-consuming process. It is desirable, from a cost, time, and sample size perspective, to find other methodologies for estimating these traits. Because sweetness is the most heritable trait and it has a significant positive relationship to the roasted peanut trait, the possible relationships between heritable sensory traits and 18 carbohydrate components (inositol, glucose, fructose, sucrose, raffinose, stachyose, and 12 unknown peaks) in raw peanuts from 52 genotypes have been investigated. Previously reported correlations among sweet, bitter, and roasted peanut attributes were evident in this study as well. Where there was positive correlation of total sugars with sweetness, there also was positive correlation of total sugars with roasted peanut attribute and negative correlation of total sugars with bitterness and astringency. The expected generalized relationship of total sugars or sucrose to sweetness could not be established because the relationship was not the same across all market-types. Further work is needed to determine the nature of the chemical components related to the bitter principle, which appear to modify the sweet response and interfere with the sensory perception of sweetness, particularly in the Virginia market-type. Also, certain carbohydrate components showed significant relationships with sensory attributes in one market-type and not another. These differential associations demonstrate the complexity of the interrelationships among sweet, bitter, and roasted peanut sensory attributes. Within two market-types it is possible to improve the efficiency of selection for sweetness and roasted peanut quality by assaying for total carbohydrates. On the basis of the regression values the greatest efficiency would occur in the fastigiate market-type and then the runner.
Negative ion mass spectra of some unsaturated <i>C</i>‐glycosides following keV ion bombardment (1992)

Abstract A series of anomeric unsaturated C ‐glycosides were studied by negative ion mass spectrometry following keV ion bombardment The compounds bearing an acidic hydrogen show a prominent [M  H] − peak; in the other cases, the [M  H] − peak is of very low intensity. A retro‐Diels–Alder fragmentation and the abstraction of a hydrogen atom from the aglycon residue are observed in all cases.