gebhart/patrepeval huggingface dataset:
The Fate of C14-Labeled Palmitic Acid Administered Intravenously as a Tripalmitin Emulsion. (1949)

Summary1. In order to test the extent of utilization of fat emulsions in parenteral feeding, palmitic acid labeled with C14 at its sixth carbon was injected intravenously, in the form of the triglyceride, into fasted rats.2. From 36 to 59% of the administered C14 was expired as CO2 in 24 hours.3. Considerable amounts of the administered fatty acids were stored in adipose tissues throughout the body.4. The availability of intravenously administered tripalmitin for metabolic purposes is further shown by the finding that as much as 78% of the radioactive fatty acids recovered from the liver and small intestine had been incorporated into phospholipids.
Chapter 4. Reaction mechanisms. Part (iii) Free-radical reactions (1994)

S. Caddick and K. Aboutayab, Annu. Rep. Prog. Chem., Sect. B: Org. Chem., 1994, 91, 103 DOI: 10.1039/OC9949100103
Dynamic filter and other solutions to the subsynchronous resonance problem (1975)

This paper discusses subsynchronous resonance (SSR) problems in series capacitor compensated transmission systems. It also describes the operation of a number of devices that have been proposed to control or eliminate these problems. The greatest emphasis is given to the dynamic filter for control of self-excited oscillations and to dual level by-pass gap control of the series capacitors to reduce the transient torques on turbine generator shafts resulting from transmission system disturbances.
Bioluminescence Imaging of Mouse Models of Human Cancer (2004)

Abstract The increasing sophistication of rodent models of human neoplastic disease has led to models that more closely approximate human disease where lesions can arise at various times and locations. The uncertainty of initiation and progression of disease and the complexity of these models have necessitated advancement and refinement of noninvasive imaging technologies that can reveal cellular and molecular changes in the context of the living animal. One of these technologies, in vivo bioluminescent imaging, uses internal biologic sources of light, luciferases, as reporters of biologic change in these models. This optical imaging modality is based on the transmission of light through mammalian tissues, and the sensitivity of detecting photonic signals from within the body, as with other optical modalities, is governed by the absorbing and scattering properties of tissue. In vivo imaging of luciferase activity has been used to reveal patterns of transcription, levels of protein–protein interaction, extent of tumor burden, sites of metastatic disease, location of immune cell migration, and mechanisms of oncogenesis. High signal‐to‐noise ratios result in sensitive in vivo measurements, and the ability to label a variety of steps in oncogenesis enables unprecedented in vivo cellular and molecular dissection of disease processes.
Modelling of submerged membrane flocculation hybrid systems using statistical and artificial neural networks methods (2010)

Hybrid membrane filtration processes involve complex physical, chemical and biological phenomena, thus their mechanistic modelling is challenging. The chief advantages of statistical and artificial neural networks (ANN) models (data-driven models) are that they do not require assumptions and simplifications to establish relationships from data. This paper investigates the characteristics and performance of several data-driven methods to model a hybrid membrane system. The focus is on the application of regression analysis and artificial intelligence based methods to a steady-state system. Among empirically based approaches, ANN neural networks methods were found to be very useful to predict permeate quality and membrane fouling. In the past multivariate nonlinear regression had barely been investigated for process modelling in water and waste water treatment. In this study polynomial multivariate nonlinear regression showed a superior performance. Multivariate parametric nonlinear models could match the performance of the nonparametric ANN models in the empirical modelling of complex systems, especially when combined with advanced optimization methods. This paper gives the methodology of how one could optimize a membrane hybrid system using ANN, validating it with one set of data. The same procedure/methodology can be applied to similar systems.
A Safety Verification Approach to Fault-Tolerant Aircraft Supervisory Control (2011)

at the high level, here dened by a contingency envelope which demands that both aircraft performance and operational limits on the recovery actuators are conserved. The model is abstracted in such a way to reduce the computational complexity of the model but preserve the salient dynamics relevant to safety. Using a dynamic programming procedure, an optimal control congration is chosen from
Characterization of Oligo(Ethylene Glycol) and Oligoglycerol Functionalized Poly(Ether Imide) by Angle-Dependent X-Ray Photoelectron Spectroscopy (2012)

The surface functionalization of PEI with OEG and OGMe could be verified by the angle-dependent XPS. The observations proved the functionalization at the PEI surface, as the polyethers were detected at angles providing signals of the surface volume. Furthermore, the chemical functions determined verified a covalent binding via the nucleophilic addition of the amine functionalized OGMe and OEG to the PEI imide function.
Wavelets in Image Communication (1994)

Part 1 Biorthogonal wavelets and dual filters, A. Cohen: abstract the construction of biorthogonal wavelets examples in 1-D biorthogonal splines the Burt-Adelson wavelets optimizing the dual filter design examples in 2-D the quincunx sublattice construction the hexagonal construction references. Part 2 Non rectangular wavelet representation of 2-D signals - application to image coding, C. Guillemot et al: abstract nonrectangular wavelet representation of 2-D signals nonseparable 2-D wavelets nonrectangular multiresolution representation construction of bases for the representation of Quincunx-sampled signals 1-D wavelet construction using Lagrange halfband filters construction of nonrectangular 2-D orthogonal bases construction of biorthogonal bases application to image coding summary references. Part 3 Wavelet transform and image coding, M. Antonini et al: abstract wavelet transform definition of wavelets multiresolution analysis - scaling function multiresolution analysis and digital filter banks quality criteria for wavelets used in image processing biorthogonal wavelets extension to the bidimensional case statistical properties of wavelets coefficients. Appendices: vector quantization quantization codebook entropy vector quantization versus scalar quantization codebook design lattice vector quantization (LVQ) bit allocation procedure experimental results lattice vector quantizer design coding under psychovisual considerations dyadic or quincunx scheme for coding? acknowledgements. Part 4 A region-based discrete wavelet transform (RBDWT) for image coding, H.J. Barnard et al: abstract the discrete wavelet transform region-based coding principle of the region-based discrete wavelet transform scope and organization the implementation of RBDWT decomposition of the segmentation mask filtering and downsampling with the RBDWT the coding scheme the segmentation the bit allocation the quantization comparison to the standard DWT coding scheme theoretical advantages and disadvantages of the RBDWT coding scheme experimental comparison of the RBDWT and the standard DWT coding schemes multiresolution coding of images using the RBDWT application to video coding conclusions and further research. Part 5 Wavelet transform and motion estimation for image sequence coding - a multiconstraint approach, N. Baaziz and C. Labit: abstract multiresolution representations of image sequences a generalized typology of multiresolution decompositions comparison based on local and global subband entropies discussion monoresolution motion estimation framework adaptive pel-recursive motion estimation algorithm Wiener-based algorithm modified Wiener-based approach multiresolution motion estimation problem statement multigrid Walker-Rao algorithm on wavelet pyramids multiconstraint algorithm.
Hamster Model of Leptospirosis (2006)

This unit describes the techniques involved in the hamster model of leptospirosis. Hamsters are exquisitely susceptible to infection with pathogenic Leptospira species. The LD(50) of virulent Leptospiral strains by intraperitoneal inoculation of 3- to 4-week-old hamsters is as low as a single organism. The pathogenesis of severe leptospirosis in the hamster is a model of accidental infections observed in nature in many mammals, including humans. Animal husbandry issues and the reproducibility of the hamster model make it the animal model of choice for Leptospiral vaccine and antibiotic treatment studies.
Hydroperoxidation de polymères par réaction avec l'oxygène singulet et greffage de monomères hydrosolubles par décomposition des hydroperoxides formés (1997)

Doctorat en Sciences
A new technique to teach basic concepts of refraction and reflection of light (2009)

Nature of light is a fascinating subject of education and training for children. However, it is not easy to demonstrate and explain fundamental properties of the light to the primary & secondary school students. In this paper, we will present a new technique to teach concept of refraction, reflection, and total internal reflection of light in glasses by utilizing deviation angles of a prism for various surrounding index-matching oils.
Ressource sharing on the teraflop scale for the biomedical research and care sector – The Erasmus Computing Grid and MediGRID. (2008)

Today advances in scientific research as well as clinical diagnostics and treatment are inevitably connected with information solutions concerning computation power and information storage. The needs for information technology are enormous and are in many cases the limiting factor for new scientific results or clinical diagnostics and treatment. At the same time huge computing and storage resources (e.g. ~109 personal computers in the private, public, and industrial domains) have been installed which outwheigh the resources at high-performance computing centers ~50-100 times and thus could contribute to the challenges mankind faces. Both the Erasmus Computing Grid (ECG) and the MediGRID are two major working resource-sharing entities at public funded organizations: \n\ni) The ECG in Rotterdam exploits currently the desktop computers of the Erasmus Medical Center (the biggest biomedical research and hospital center in The Netherlands) and the Hogheschool Rotterdam (one of the biggest city universities in The Netherlands) and consists of ~104 hosts with ~ 10 TeraFlops capacity (30 TeraFlops at the end of 2008). The ECG has grown into a vital part of the work of \nthe ~10 user groups as well as the organizations, with results which could not have been done without the ECG. \n\nii) The MediGRID being part of the German D-Grid initiatives connects local dedicated cluster resources at biomedical universities throughout Germany with a capacity of ~2000 hosts with ~2 TeraFlops capacity. Within MediGRID ~15 user groups conduct basic research as well as clinical applications for diagnosis and treatment. Again the results could hardly be obtained otherwise and thus have provided breakthroughs. \n\nTo build these infrastructures two e-social influences had to be overcome: i) the sharing attitude and socialization of the individual, i.e. the micro-sociality, and ii) the organization culture of the embedding institution, i.e. the macro-sociality, as e.g. for the ECG the public funded organizations. Operationally, an these factors were adressed by: i) the participative integration of fundamental IT applications of major users, and ii) the setup of an open and sustainable management structure.Consequently, we show that the IT challenges mankind faces in the biomedical research and health-care sectors can be successfully approached by appropriate exploitation of the huge existing resources by grid technology combined with micro and macro e-social means to stimulate sharing on the individual as well as organizational level.
Use of Dipsticks for Rapid Diagnosis of Cholera Caused by <i>Vibrio cholerae</i> O1 and O139 from Rectal Swabs (2003)

We evaluated the recently developed dipsticks for the rapid detection of Vibrio cholerae serotypes O1 and O139 from rectal swabs of hospitalized diarrheal patients after enrichment for 4 h in alkaline peptone water. The sensitivity and specificity of the dipsticks were above 92 and 91%, respectively. The dipsticks represent the first rapid test which has been successfully used to diagnose cholera from rectal swabs, and this would immensely improve surveillance for cholera, especially in remote settings.
Electron diode with a large area ferroelectric plasma cathode (2001)

The operation of a planar diode with a large area (64 cm2) ferroelectric plasma cathode based on BaTiO3 ceramics is studied. Diode parameters and parameters of the generated electron beam are investigated under accelerating voltage of 200–350 kV and pulse duration of 250 ns. Parameters of the plasma, which forms on the surface of the ferroelectric cathode due to incomplete discharge, are reported as well. It is shown that the application of this cathode allows one to produce an electron beam simultaneously with application of the accelerating pulse. The generation of an electron beam with current density up to 20 A/cm2 and divergence of less than 1° is demonstrated. It is shown that diode operation is governed by parameters of the cathode plasma which fills the anode–cathode gap prior to application of the accelerating voltage pulse. By proper adjustment of the cathode and diode parameters the operation of the diode with almost constant impedance is achieved. Measurements of the potential distribution in the diode confirm that the diode operates in a plasma-prefilled mode. The cathode is found to be capable of operating for up to 105 pulses at a repetition rate of few Hz without any maintenance and with relatively small vacuum deterioration.
Polymer–Ceramic Composite Electrolytes for Lithium Batteries: A Comparison between the Single-Ion-Conducting Polymer Matrix and Its Counterpart (2020)

Single-ion-conducting polymer electrolytes are attractive to use in lithium batteries as the transference number of the lithium cation approaches unity. This helps prevent concentration gradients across the electrolyte, which can result in dendrite formation. The addition of ceramic particles to polymer electrolytes at high loadings can increase the mechanical strength of the polymer, which can also help suppress dendrite formation. Here, a single-ion-conducting polymer electrolyte is blended with lithium-conducting oxide ceramic particles to make a composite electrolyte. This electrolyte is studied in comparison to a composite electrolyte containing freely dissolved lithium salt. It is found that the addition of ceramic particles to the single-ion-conducting polymer can result in increased cation dissociation and consequent increased ionic conductivity. The electrolytes are cycled in lithium symmetrical cells, and it is found that the ceramic-containing electrolytes show increased interfacial stability with the lithium metal compared to the pristine polymer electrolytes. Our findings shed light on how to optimize the polymer host chemistry to form composite electrolytes that can meet the challenging requirements to stabilize the lithium metal anode.
A review of some recent developments in polarization-sensitive optical imaging techniques for the study of articular cartilage (2009)

This article reviews recent developments in the optical imaging of articular cartilage using polarized-light methods, with an emphasis on tools that could be of use in tissue engineering approaches to treatment. Both second-harmonic generation microscopy and polarization-sensitive optical coherence tomography are described and their potential role in the treatment of cartilage disorders such as osteoarthritis is suggested. Key results are reviewed and future developments are discussed.
Macrophage Inflammatory Protein-1α and Stem Cell Inhibition (1999)

Much interest has recently focused on the regulation of hemopoietic stem cell (HSC) proliferation as such studies are of fundamental importance in a range of therapeutic contexts. For example, both inhibitors and stimulators of stem cell proliferation have potential roles to play in alleviating myelosuppression following chemotherapeutic cancer treatments. In addition, the ability to manipulate the proliferative status of the HSC may be crucial in assuring the efficacy of gene therapeutic regimes. This chapter outlines the biology of the hemopoietic system and sets out to define the role of macrophage inflammatory protein-1α (MIP-lα) as an inhibitor of HSC proliferation.
Practical aspects of acoustic plastic pipe location (1993)

Many gas distribution company operation and maintenance activities require precise knowledge of the location of buried plastic piping. Plastic pipe cannot be located if the tracer wire is gone or was never installed. Under sponsorship of the Southern California Gas Company, IGT successfully demonstrated an acoustic plastic pipe location technique and is developing the technique into a practical field instrument an acoustic signal is injected directly into the gas at a service. The acoustic signal travels in the gas in the pipes, not in the pipe wall. As the acoustic wave travels along the pipe, some of the sound radiates from the pipe through the soil to the surface of the ground. An array of sensors on the surface of the ground perpendicular to the pipe detects the acoustic signal, thereby locating the Pipe. Two different acoustic measurements are used. The first measurement locates the pipe to within {plus_minus} 3-ft. Then the second technique determines the location of the pipe to within {plus_minus} 6-in.
Pathogenesis of Chandler's syndrome, essential iris atrophy and the Cogan-Reese syndrome. II. Estimated age at disease onset. (1986)

The presence of a layer of abnormal material in Descemet's membrane in eight keratoplasty specimens served as a marker to determine whether Chandler's syndrome, Essential Iris Atrophy, and the Cogan-Reese syndrome are congenital or acquired conditions. In all eight cases of the ICE syndrome, a pattern of membrane deposition was observed, which typifies acquired disorders: a completely normal prenatal layer and both normal and abnormal portions of the postnatal layer. The thickness of the membrane deposited before the onset of abnormal secretion was used to estimate a time span for possible ages at which abnormal secretion began. The estimated age intervals for all diseased specimens had their lower limits in the postnatal period. Thus, these results led us to the conclusion that abnormal Descemet's membrane first appeared in postnatal life, years before clinical recognition of disease. The possibility of a viral etiology for this unilateral endotheliopathy resulting in an altered Descemet's membrane is discussed.
Mechanistic Studies on the Copper‐Catalyzed Hydrosilylation of Ketones (Eur. J. Inorg. Chem. 4/2010) (2010)

Abstract The cover picture shows the Aiguille du Midi, Mont Blanc massif, France. The mechanism of the copper‐catalyzed hydrosilylation of ketones has been determined by experimental mechanistic investigations and computational studies. The insertion of the ketone into the Cu–H bond was found to have a lower activation barrier than the reaction of the copper alkoxy intermediate with the silane that regenerates the Cu–H bond along with the silyl ether product, as shown in the picture. Details are discussed in the article by A. Dedieu, S. Bellemin‐Laponnaz et al. on p. 529 ff.
AN ANTIMALARIAL ALKALOID FROM HYDRANGEA. XXIII. SYNTHESIS BY THE PYRIDINE APPROACH. II (1955)

ADVERTISEMENT RETURN TO ISSUEPREVArticleAN ANTIMALARIAL ALKALOID FROM HYDRANGEA. XXIII. SYNTHESIS BY THE PYRIDINE APPROACH. IIB. R. BAKER and FRANCIS J. McEVOYCite this: J. Org. Chem. 1955, 20, 1, 136–142Publication Date (Print):January 1, 1955Publication History Published online1 May 2002Published inissue 1 January 1955https://pubs.acs.org/doi/10.1021/jo01119a020https://doi.org/10.1021/jo01119a020research-articleACS PublicationsRequest reuse permissionsArticle Views339Altmetric-Citations30LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Parasite control methods used by horse owners: factors predisposing to the development of anthelmintic resistance in nematodes (2000)

One hundred and fifty horse owners, primarily private owners and riding schools, replied to a questionnaire concerning the practices they used to control parasites. Twenty-seven had experienced a parasite problem. Faecal samples from 188 horses selected at random showed that worm control practices were generally successful; however, many owners were not following recommendations for slowing the development of resistant parasites. In 1996, 86 per cent of the owners were using either three or two classes of anthelmintic a year, and they used a median of six doses with a range from one to 11. Approximately half the owners, more commonly owners of up to five horses, picked up their horses' faeces at least once a week, but these owners also used more doses of anthelmintic a year than owners who did not pick up faeces. One-third of the owners manually removed Gasterophilus species eggs from the horses' hairs, but 94 per cent of them also used ivermectin. Many owners treated specifically for Anoplocephala species, cyathostome larvae and Gasterophilus species, and these owners were the most likely to use three classes of anthelmintic a year. One-hundred-and-seven owners replied to a second questionnaire asking for information about the factors that influenced their anthelmintic control practices. Many owners, particularly private owners, were not influenced by the cost of the anthelmintic. For the timing and frequency of treatment, and the choice of drug, owners were most influenced by advertisements, magazine articles and veterinary surgeons. In two magazines aimed at horse owners, the brands of drugs most frequently advertised were the brands most commonly used by the owners, and articles in the magazines recommended the use of three classes of drug per year. These results are discussed in relation to their influence on the development of anthelmintic-resistant nematodes.
Influence of surface charge on the potential toxicity of PLGA nanoparticles towards Calu-3 cells (2011)

These in vitro results highlight the safety of biodegradable PLGA nanoparticles in the bronchial epithelium and provide initial data on their potential effects and the risks associated with their use as nanomedicines.