gebhart/patrepeval huggingface dataset:
Antimicrobial activity of Eucalyptus citriodora essential oil (2008)

Abstract The antimicrobial activity of Eucalyptus citriodora essential oil against pathogenic fungi, bacteria and drug-resistant mutants of Candida albicans , Escherichia coli and Mycobacterium smegmatis was evaluated following agar disc diffusion and broth dilution assay procedures both qualitatively and quantitatively. The essential oil of E. citriodora was found to be active against Trichophyton rubrum followed by Histoplasma capsulatum , Candida albicans (MTCC) and Cryptococcus neoformans . Similarly, it was found active toward Gram-positive bacteria compared to Gram-negative and showed activity towards drug-resistant mutants of C. albicans and E. coli . The findings of our pilot study suggest that characterization and isolation of the active phytoceutical(s) from the E. citriodora oil may provide a valuable antimicrobial agent for counteracting fungal and drug-resistant infections. Key words: Eucalyptus citriodora , antimicrobial, bacteria, fungi, drug resistant mutants EORC erc * Corresponding author.
An overview on systems of systems control : general discussions and application to multiple autonomous vehicles (2019)

La thèse porte sur le contrôle des systèmes de systèmes (SdS) et, sur la manière de construire des SdS adaptables et fiables. Ce travail fait partie du laboratoire d’excellence Labex MS2T sur le développement des SdS technologiques. Les SdS sont des systèmes complexes constitués de plusieurs systèmes indépendants qui fonctionnent ensemble pour atteindre un objectif commun. L’ingénierie des SdS est une approche qui se concentre sur la manière de construire et de concevoir des SdS fiables capables de s’adapter à l’environnement dynamique dans lequel ils évoluent. Compte tenu de l’importance du contrôle des systèmes constituants (SC) pour atteindre les objectifs du SdS , la première partie de cette thèse a consisté en une étude bibliographique sur le sujet du contrôle des SdS. Certaines méthodes de contrôle existent pour les systèmes à grande échelle et les systèmes multi-agents, à savoir, le contrôle hiérarchique, distribué et décentralisé peuvent être utiles et sont utilisés pour contrôler les SdS. Ces méthodes ne conviennent pas pour contrôler un SdS dans sa globalité et son évolution, en raison de l’indépendance de leur SC ; alors que les “frameworks” multi-vues conviennent mieux à cet objectif. Une approche de ”framework” générale est proposée pour modéliser et gérer les interactions entre les SC dans un SdS. La deuxième partie de notre travail a consisté à contribuer aux systèmes de transport intelligent. À cette fin, nous avons proposé le gestionnaire de manœuvres coopératives pour les véhicules autonomes (CMMAV), un “framework” qui guide le développement des applications coopératives dans les véhicules autonomes. Pour valider le CMMAV, nous avons développé le gestionnaire de manœuvres latérales coopératives (CLMM), une application sur les véhicules autonomes qui permet d’échanger des demandes afin de coopérer lors de manœuvres de dépassement sur autoroute. Cette application a été validée par des scénarios formels, des simulations informatiques, et testée sur les véhicules autonomes du projet Robotex au laboratoire Heudiasyc.
Optimization of Precipitation Hardened Fe-Ni-Cr Alloys Using Nickel Ion Bombardment Simulation Studies (1982)

Two precipitation hardened Fe-Ni-Cr alloys were irradiated with nickel ions to simulate neutron irradiation and evaluate the in-reactor swelling and phase stability of these materials. Based upon the results of these tests, minor chemical adjustments were made to the base chemistry which will improve in-reactor phase stability and swelling resistance. The alloys were preinjected with 5 appm He and Ni-ion irradiated in an aged condition to a maximum dose of ∼250 dpa at temperatures between 500°C and 750°C. Surface profilometry measurements on sheet samples showed a small swelling peak at 550°C for one alloy and at 500°C for the other. Very low swelling (less than 1%) was measured by TEM in both alloys irradiated in disc form at 550°C to a dose of ∼220 dpa. The steady-state swelling rates at the peak temperatures were 0.015%/dpa with incubation doses of 145 dpa. The pre-existing spherical γ' precipitates in the alloys assumed irregular shapes under Ni-ion bombardment and their size distribution broadened without significant change in the average size (∼12 nm) or volume fraction (1–2%). Substantial radiation-induced precipitation (other than γ') was observed in both alloys. Dark field microscopy and electron diffraction analysis were used to identify the precipitates. It was established that a deleterious G-phase precipitation could be eliminated by reducing the silicon content from 1.0% to 0.1%, without affecting the swelling resistance of the alloys. A reduction in the Mo content was also recommended based on phase stability considerations.
ChemInform Abstract: New Types of Liposidomycins That Inhibit Bacterial Peptidoglycan Synthesis and are Produced by Streptomyces. Part 2. Isolation and Structure Elucidation. (1998)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
A trace-based Java JIT compiler retrofitted from a method-based compiler (2011)

This paper describes our trace-based JIT compiler (trace-JIT) for Java developed from a production-quality method-based JIT compiler (method-JIT). We first describe the design and implementation of our trace-JIT with emphasis on how we retrofitted a method-JIT as a trace-based compiler. Then we show that the trace-JIT often produces better quality code than the method-JIT by extending the compilation scope. Forming longer traces that span multiple methods turns out to be more powerful than method inlining in extending the compilation scope. It reduces method-invocation overhead and also offers more compiler optimization opportunities. However, the trace-JIT incurs additional runtime overhead compared to the method-JIT that may be offset by gains from the improved code quality. Overall, our trace-JIT achieved performance roughly comparable to the baseline method-JIT. We also discuss the issues in trace-based compilation from the viewpoint of compiler optimizations. Our results show the potentials of trace-based compilation as an alternative or complementary approach to compiling languages with mature method-based compilers.
The basal endosperm transfer layer (BETL): gateway to the maize kernel. (2017)

The maize basal endosperm transfer layer (BETL), with its unique location at the juncture of maternal and filial tissues, plays a critical role in grain-filling and defense. Symplastic discontinuity between the mother plant and BETL is elaborated through programmed cell death in the placenta-chalaza region. This chapter provides insights into the structure, function, and signalling roles of the BETL. This will foster future research into the development and function of this important seed tissue. Future directions are mentioned.
Cytokine profile, HLA restriction and TCR sequence analysis of human CD4+ T clones specific for an immunodominant epitope of <i>Mycobacterium tuberculosis</i> 16-kDa protein (2003)

SUMMARY The identification of immunodominant and universal mycobacterial peptides could be applied to vaccine design and have an employment as diagnostic reagents. In this paper we have investigated the fine specificity, clonal composition and HLA class II restriction of CD4+ T cell clones specific for an immunodominant epitope spanning amino acids 91–110 of the 16-kDa protein of Mycobacterium tuberculosis. Twenty-one of the tested 28 clones had a Th1 profile, while seven clones had a Th0 profile. None of the clones had a Th2 profile. While the TCR AV gene usage of the clones was heterogeneous, a dominant TCR BV2 gene family was used by 18 of the 28 clones. The CDR3 regions of BV2+ T cell clones showed variation in lengths, but a putative common motif R-L/V-G/S-Y/W-E/D was detected in 13 of the 18 clones. Moreover, the last two to three residues of the putative CDR3 loops, encoded by conserved BJ sequences, could also play a role in peptide recognition. Antibody blockade and fine restriction analysis using HLA-DR homozygous antigen-presenting cells established that 16 of 18 BV2+ peptide-specific clones were DR restricted and two clones were DR-DQ and DR-DP restricted. Additionally, five of the 18 TCRBV2+ clones recognized peptide 91–110 in association with both parental and diverse HLA-DR molecules, indicating their promiscuous recognition pattern. The ability of peptide 91–110 to bind a wide range of HLA-DR molecules, and to stimulate a Th1-type interferon (IFN)-γ response more readily, encourage the use of this peptide as a subunit vaccine component.
Olanzapine Versus Ziprasidone: Results of a 28-Week Double-Blind Study in Patients With Schizophrenia (2005)

Olanzapine treatment resulted in significantly greater psychopathology improvement and higher response and completion rates than ziprasidone treatment, while ziprasidone was superior for weight change and lipid profile.
Coriolis Erosion Testing Approach for Relatively Thick Coatings (2007)

Abstract To meet the challenge of wear and corrosion attack in various applications, coating has been an effective protection approach for the work surface of engineering components, including slurry pump wet-end parts (e.g., impellers, liners, and shells). The coated wear parts that handle flowing slurry are exposed to both sliding and impact erosion along with possible corrosion factors. In such erosive wear conditions, relatively thick coatings including overlays may be needed to extend service life of the wear components. Different wear testing methods have been used to evaluate the tribological properties of coating materials under both dry and wet wear conditions. Previous studies have shown that Coriolis erosion testing is a valuable and effective approach to study erosive wear behaviors of materials in flowing slurry conditions such as within a centrifugal slurry pump system. Although extensive research can be found on wear of hard coating materials, coating erosive wear research conducted using Coriolis wear testing methods is very limited. This paper demonstrates that Coriolis erosion testing can be applicable for both sliding and impact wear on relatively thick coatings (typically, 250 μm or thicker). By adjusting test parameters within the Coriolis erosion testing system, such as flow rate (or solids particle velocity), solids type, size, and concentration, and impact angle, various types of coatings can be tested for different erosive wear conditions. Through such Coriolis erosion testing, erosion rate and tribological characteristics of coatings can be determined and evaluated. The coating examples used in this study include NiCrSiB, NiWCrSiB, WC-NiCrSiB, and WC-Co-Cr coatings produced with flame-spray, sintering and/or high-velocity-oxygen-fuel (HVOF) and high-velocity-air-fuel (HVAF) processes. Some related factors have also been discussed.
Priority queueing system with fixed-length packet-train arrivals (1998)

A discrete-time priority queueing system is studied, in which two different classes of fixed-length packet-trains arrive according to independent batch geometric streams. The packets in each packet-train arrive at the rate of one packet per slot (train arrivals), resulting in a correlated arrival stream. The service time of one packet is deterministic of one slot. The motivation for the work comes from ATM networks with diverse traffic sources and correlated packet arrival stream. Using the probability generating function method, the joint distribution of queue lengths and the waiting time distribution are obtained for each class. Numerical results are presented. Comparision is made with the case of ‘batch arrivals’, where all packets of a packet-train arrive simultaneously at the buffer.
Bronchoscopic aspects of renal cell carcinoma (RCC). (1999)

A symposium on RCC in July 1998 in Tübingen was where we to reviewed our patients with endobronchial metastatic RCC treated by bronchoscopy since 1981. 24 of 26 consecutive cases are the subject of the present study. Tumor history, X-ray findings, endobronchial appearance, treatment and the pathogenetic mechanisms of this special form of metastatic spread are demonstrated and discussed. In 5 patients > 10 years relapsed between nephrectomy and bronchoscopic tumor therapy. A thrombuslike tumor growth and bleeding were striking bronchoscopic features. In X-ray besides atelectasis, hilar or mediastinal masses were seen half of the patients, in 50% without parenchymal lung nodes, suggesting lymphogenic spread. In several patients bronchial recanalisation could be successfully repeated over long periods. Abnormal X-ray, haemoptysis or dyspnoa in patients with RCC demands bronchoscopy. In case of bronchial tumor obstruction bronchoscopic treatment offers excellent palliation.
Comparative study of the polypeptide profiles and functional properties of <i>Sinapis alba</i> and <i>Brassica juncea</i> seed meals and protein concentrates (2005)

Abstract Defatted meals and protein concentrates from six accessions of Sinapis alba and one accession of Brassica juncea mustard seeds were analysed for their polypeptide profile and functional properties. Two types of protein concentrates were prepared using acid‐induced and calcium‐induced protein precipitations. Meals from the S alba seeds had similar polypeptide composition, which was different from that of the B juncea meal. Non‐reducing sodium dodecyl sulfate polyacrylamide gel electrophoresis showed that two of the major polypeptides (50 and 55 kDa) in S alba seeds were susceptible to acid‐induced precipitation but resistant to calcium‐induced precipitation. The B juncea meal proteins were significantly ( p ≤ 0.05) more susceptible to heat coagulation than the S alba meal proteins. Emulsifying activity index was significantly higher ( p ≤ 0.05) in the B juncea meal and protein concentrates when compared with similar products from S alba . It was concluded that the presence of a high‐molecular‐weight (135 kDa) disulfide‐bonded polypeptide could have contributed to the lower emulsifying power of the S alba products when compared with the B juncea proteins that do not have this polypeptide. Copyright © 2005 Society of Chemical Industry
Application of priority service pricing for mobilizing residential demand response in Belgium (2017)

Demand-side management is a promising approach for dealing with the increasing integration of renewable energy resources. In order to mobilize residential demand response, we revisit a paradigm based on priority service pricing. In this paradigm, electricity supply is perceived as a service that can be offered with various degrees of quality, where the specific measure of quality considered in this paper is reliability. The motivation of priority service pricing is to achieve massive mobilization of residential demand response resources while respecting the requirement of consumers for simplicity, privacy and control. In this paper, we apply priority service theory on Belgium to design such a contract for residential consumers.
The Big Picture (2020)

Here's the most important lesson in this whole book: you need to own your own career, because no one else will guide you. Good mentorship can be wonderful for the .01% of engineers who find it, but in all likelihood, you are going to teach yourself 99% of everything you'll learn as a professional; great projects may fall into your lap once in a blue moon, but more often, you'll have to find your way to them yourself. Therefore, the most important tools in your toolbox are going to be personal responsibility and initiative; those qualities are what make you a trustworthy (and valued) professional, but also how you grow and advance. We'll discuss this principle in many contexts throughout the book.
Preparation and properties of APPSSQ‐like/polyimide hybrid composites (2003)

Abstract Hydrolysis and condensation proceeded to generate 3‐aminopropyl polysilsesquioxane‐like (APPSSQ‐like) particles from 3‐aminopropyl triethoxysilane. An APPSSQ‐like particle includes two domains: crosslinking SiOSi networks inside and 3‐aminopropyl groups outside the particle. The APPSSQ‐like/polyimide (APPSSQ‐like/PI) hybrid composites were prepared from a solution of poly(amic acid) (PAA, polyimide precursor) and APPSSQ‐like particles using N , N ‐dimethylacetamide as a solvent. Scanning electron microscopy (SEM) showed that the APPSSQ particle sizes were about 100 nm, and there was no obvious phase separation between the APPSSQ‐like particles and the PI matrix in the fracture surfaces of the hybrid films. Owing to the highly crosslinked SiOSi networks inside the APPSSQ‐like particles, the APPSSQ‐like/PI hybrid composites possessed desired properties such as improved thermal resistance and reduced coefficients of thermal expansion (CTE). The presence of covalent bonds between the APPSSQ‐like particles and the PI molecules improved the compatibility between these two components. Thus, the tensile strength increased with the APPSSQ‐like content, and the elongation at break also slightly increased with the APPSSQ‐like content. The initial tensile and storage moduli of the APPSSQ‐like/PI hybrid composites increased with the APPSSQ‐like content, which indicates that the mechanical properties of these hybrid composites were enhanced by the incorporation of the APPSSQ‐like content in the PI matrix. Furthermore, the glass transition temperatures of these composites increased with the APPSSQ‐like content because the adhesion between the APPSSQ‐like particles and the PI molecules restricts the PI chains' mobility. © 2003 Wiley Periodicals, Inc. J Appl Polym Sci 89: 2865–2874, 2003
Coordination of Differential Effects of Primary Estrogen and Catecholestrogen on Two Distinct Targets Mediates Embryo Implantation in the Mouse**This work was supported, in part, by NIH Grant HD-12304 and as part of the National Cooperative Program on Markers of Uterine Receptivity for Blastocyst Implantation [NIH Grants HD-29968 (to S.K.D.), HD-35114 (to B.C.P.), and ES-07814 (to S.K.D.)]. A center grant in Reproductive Biology (HD-33994) and a center grant in Mental Retardation and Developmental Disabilities (HD-02528) provided access to various core facilities. (1998)

In the mouse, estrogen is essential for blastocyst implantation in the progesterone (P4)-primed uterus. The mechanism(s) by which estrogen initiates this response still remains elusive. The present investigation, using delayed implantation in the mouse, examined the differential role of estradiol-17beta (E2) and its catechol metabolite 4-hydroxy-E2 (4-OH-E2) in uterine and blastocyst activation for implantation. The conditions of delayed implantation were induced by ovariectomizing mice on day 4 (day 1 = vaginal plug) of pregnancy or pseudopregnancy and maintaining them with P4 from days 5-7. The binding of EGF to blastocysts was used as a marker for blastocyst activation. Our results show that whereas E2 fails to activate dormant blastocysts (with respect to EGF binding in vitro), 4-OH-E2, cAMP, or prostaglandin E2, is effective in this response. Further, whereas 4-OH-E2 induced-activation is not blocked by an antiestrogen, an inhibitor of PG synthesis, adenylyl cyclase or protein kinase A effectively blocks this activation. These results suggest that 4-OH-E2 effects on blastocysts are mediated by PGs, which, in turn, stimulate cAMP production and thus activation of protein kinase A. Two-fluoro-E2 is a poor substrate and an inhibitor of catecholestrogen synthesis, but it is estrogenic, with respect to uterine growth and gene expression. Using blastocyst transfer experiments, we observed that dormant blastocysts incubated with 4-OH-E2 in vitro, but not with E2, are capable of implanting in P4-treated delayed implanting mice receiving two-fluoro-E2. The results suggest that whereas E2 is necessary for preparation of the uterus, uterine-derived catecholestrogen is important for blastocyst activation for implantation. Indeed, the receptive uterus has the capacity to synthesize 4-OH-E2. Collectively, we demonstrate that the primary ovarian estrogen E2, via its interaction with nuclear estrogen receptors, participates in the preparation of the P4-primed uterus to the receptive state in an endocrine manner, whereas its metabolite 4-OH-E2, produced from E2 in the uterus, mediates blastocyst activation for implantation in a paracrine manner. Our results also establish that these target-specific effects of primary estrogen and catecholestrogen are both essential for implantation and that successful implantation occurs only when the activated stage of the blastocyst coincides with the receptive state of the uterus.
Role of toll like receptors in the antibody response to encapsulated bacteria (2012)

Encapsulated bacteria are major pathogens in humans. The capsular polysaccharides (PS) of these bacteria are T-independent type 2 antigens, are not processed by antigen presenting cells and do not induce T cell help. PS antigens are poor immunogens in children less than two years, the peak age incidence of encapsulated bacterial infection. The TNF family receptors BAFFR and TACI interaction with the cytokines BAFF and APRIL are essential co-stimulatory factors for humoral responses to PS. Linkage of PS to a carrier protein to make glycoconjugate vaccines, enhances the immune response to PS similar to a T cell dependent antigen. Multiple doses of glycoconjugate vaccines are required to elicit protection, making their use in the developing world problematic. TLR engagement augments BAFF mediated PS antibody responses and TLR ligands serve as adjuvants for induction of anti-PS antibodies either for pure PS or for PS-protein conjugate vaccines. A variety of TLR ligands stimulate increased production of antibodies directed to both PS and protein components of encapsulated bacteria, and glycoconjugate vaccines, suggesting their future role in immunization strategies.
Frequency Synthesizing Tuning System with Saw Device (1980)

Recently many kinds of TV digital tuning systems have been developed. Especially in the United States the PLL frequency synthesizing method has been widely used. This system has advantages such as 10-key direct addressing, digital channel indication, high stability and accuracy of the local oscillator frequency, and so on. However it has also disadvantages such as harmonic interferences caused by a 1000 MHz ECL prescaler, and radiation from the prescaler which needs a large input level of 0.3 ~ 1 Vp-p.