gebhart/patrepeval huggingface dataset:
Exploiting the locality of memory references to reduce the address bus energy (2002)

Article Exploiting the locality of memory references to reduce the address bus energy Share on Authors: Enric Musoll Dept. of Computer Arch., Univ. Politècnica de Catalunya, Barcelona, Spain and National Semiconductor Corp., Santa Clara, CA Dept. of Computer Arch., Univ. Politècnica de Catalunya, Barcelona, Spain and National Semiconductor Corp., Santa Clara, CAView Profile , Tomás Lang Dept. of Elec. and Comp. Eng., Univ. of California at Irvine, Irvine, CA Dept. of Elec. and Comp. Eng., Univ. of California at Irvine, Irvine, CAView Profile , Jordi Cortadella Dept. of Computer Arch., Univ. Politècnica de Catalunya, Barcelona, Spain Dept. of Computer Arch., Univ. Politècnica de Catalunya, Barcelona, SpainView Profile Authors Info & Claims ISLPED '97: Proceedings of the 1997 international symposium on Low power electronics and designAugust 1997 Pages 202–207https://doi.org/10.1145/263272.263334Published:01 August 1997 66citation213DownloadsMetricsTotal Citations66Total Downloads213Last 12 Months0Last 6 weeks0 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteGet Access
Performance ofS-bends for integrated-optic waveguides (1998)

The performance of S-bends, which are used for connecting waveguides offset with respect to each other, is very important in integrated-optic waveguide circuits. Several approaches for the design of S-bends have been reported in the literature. These include, in particular, designs based on simple sinusoidal curves as well as relatively complicated, but more general, polynomial curves. This paper reports a comparison of the calculated pure bend loss of such S-bends for a typical silica-based waveguide operating at a wavelength of 1550 nm. It is shown that the simple cosine S-bands yield a performance which is close to that obtained from the general polynomial curve-based S-bends. Design curves are also presented for these two types of S-bends. The calculations are based on the analytical expression for bend loss proposed by Marcuse. © 1998 John Wiley & Sons, Inc. Microwave Opt Technol Lett 19: 289–292, 1998.
Detection of α-Synuclein Amyloidogenic Aggregates <i>in Vitro</i> and in Cells using Light-Switching Dipyridophenazine Ruthenium(II) Complexes (2012)

Protein aggregation is the hallmark of a number of neurodegenerative diseases including Parkinson's and Huntington's diseases. There is a significant interest in understanding the molecular mechanisms involved in the self-association and fibrillization of monomeric soluble proteins into insoluble deposits in vivo and in vitro. Probes with novel properties, such as red-shifted emission, large Stokes shifts, and high photostability, are desirable for a variety of protein aggregation studies. To respond to the increasing need for aggregation-responsive compounds suitable to cellular studies, we present a ruthenium(II) dipyridophenazine derivative, [Ru(phen)(2)dppz](2+) (phen =1,10-phenanthroline, dppz = dipyrido[3,2-a:2'.3'-c]phenazine), to study aggregation of α-synuclein (αS), which is associated with the development of Parkinson's disease. We demonstrated the use of [Ru(phen)(2)dppz](2+) to monitor αS fibril formation in real-time and to detect and quantify αS aggregates in neuroglioma cells, thereby providing a novel molecular tool to study protein deposition diseases in vitro and in vivo.
Synthesis of LiMn<sub>0.75</sub>Fe<sub>0.25</sub>PO<sub>4</sub>/C microspheres using a microwave-assisted process with a complexing agent for high-rate lithium ion batteries (2014)

LiMn<sub>0.75</sub>Fe<sub>0.25</sub>PO<sub>4</sub>/C microspheres were synthesized using a microwave-assisted process with a complexing agent through the control of precursor pH. The LiMn<sub>0.75</sub>Fe<sub>0.25</sub>PO<sub>4</sub>/C microspheres exhibited a high tap density, high capacity, remarkable rate capability, and excellent cyclability.
Modified 5′‐Trityl Nucleosides as Inhibitors of <i>Plasmodium falciparum</i> dUTPase (2011)

2'-Deoxyuridine triphosphate nucleotidohydrolase (dUTPase) is a potential drug target for the treatment of malaria. We previously reported the discovery of 5'-tritylated analogues of deoxyuridine as selective inhibitors of this Plasmodium falciparum enzyme. Herein we report further structure-activity studies; in particular, variations of the 5'-trityl group, the introduction of various substituents at the 3'-position of deoxyuridine, and modifications of the base. Compounds were tested against both the enzyme and the parasite. Variations of the 5'-trityl group and of the 3'-substituent were well tolerated and yielded active compounds. However, there is a clear requirement for the uracil base for activity, because modifications of the uracil ring result in loss of enzyme inhibition and significant decreases in antiplasmodial action.
A Developmental fMRI Study of Self-Regulatory Control in Tourette’s Syndrome (2007)

Normative developmental correlates of activity in frontostriatal circuits that subserve self-regulatory control are disturbed in persons with Tourette's syndrome. These aberrant developmental correlates are likely a consequence of greater anatomical and functional disturbances in these circuits in adults with Tourette's syndrome, which leads to impaired regulation of tic behaviors. Reduced default-mode processing in ventral prefrontal and posterior cingulate cortices in adults with Tourette's syndrome suggests the presence of greater difficulty in engaging mental processes that become active when freed from the demands of more challenging cognitive tasks. However, individuals with Tourette's syndrome appear to co-opt normal developmental processes in circuits that subserve age-related improvement in self-regulatory control while presumably struggling to maintain adequate task performance.
ChemInform Abstract: (TRIMETHYLPHOSPHINE)COBALT(I) COMPLEXES. 3. BIS(TRIMETHYLPHOSPHINE)COBALT TETRAPHENYLBORATE, THE FIRST STRUCTURAL EXAMPLE OF TETRAPHENYLBORATE ANION Π‐COORDINATED TO A FIRST‐ROW METAL ION (1985)

Abstract Die Zugabe von Na‐tetraphenylborat zu Lösungen des Co(I)‐Komplexes (I) in Methanol oder Aceton liefert die beiden Spezies (II) und (III), die durch fraktionierte Kristallisation getrennt und röntgenanalytische Strukturbe‐ Stimmungen charakterisiert werden.
Integrating pattern-based and distributional similarity methods for lexical entailment acquisition (2006)

This paper addresses the problem of acquiring lexical semantic relationships, applied to the lexical entailment relation. Our main contribution is a novel conceptual integration between the two distinct acquisition paradigms for lexical relations - the pattern-based and the distributional similarity approaches. The integrated method exploits mutual complementary information of the two approaches to obtain candidate relations and informative characterizing features. Then, a small size training set is used to construct a more accurate supervised classifier, showing significant increase in both recall and precision over the original approaches.
Identification of human neurophysins: complete amino acid sequences of MSEL- and VLDV-neurophysins. (1983)

Two human neurophysins have been purified from acetone-desiccated posterior pituitaries by acidic extraction, molecular sieving, and ion-exchange chromatography. The complete amino acid sequence of each protein has been determined by using a sequencer and characterizing two sets of overlapping enzymic peptides. The two neurophysins belong to two structural families previously defined as MSEL- and VLDV-neurophysins according to the nature of the residues in positions 2, 3, 6, and 7. (MSEL-neurophysins contain methionine-2, serine-3, glutamic acid-6, and leucine-7; VLDV-neurophysins contain valine-2, leucine-3, aspartic acid-6, and valine-7.) Human MSEL-neurophysin has only 93 residues instead of 95 usually found in MSEL-neurophysins from other mammalian species, probably because of a deletion of amino acids 91 and 92. Compared with bovine MSEL-neurophysin, nine variations (seven substitutions and two deletions) are observed. Human VLDV-neurophysin has 93 residues, as do the other mammalian VLDV-neurophysins. There are 11 substitutions when the comparison is made with bovine VLDV-neurophysin. Between the two human neurophysins, there are 26 variations. However, the central parts of the proteins (residues 10-70) are nearly identical. Furthermore, in this region identical substitutions are found in positions 29 and 60 of both neurophysins, suggesting either a single exon or some relationship between the two corresponding genes.
Scavenging of 1,4-biradicals by bis(acetylacetonato)copper(II). The importance of paramagnetic effects (1982)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTScavenging of 1,4-biradicals by bis(acetylacetonato)copper(II). The importance of paramagnetic effectsJ. C. Scaiano, Carolyn W. B. Lee, Yuan L. Chow, and Bronislaw MarciniakCite this: J. Phys. Chem. 1982, 86, 13, 2452–2455Publication Date (Print):June 1, 1982Publication History Published online1 May 2002Published inissue 1 June 1982https://pubs.acs.org/doi/10.1021/j100210a042https://doi.org/10.1021/j100210a042research-articleACS PublicationsRequest reuse permissionsArticle Views68Altmetric-Citations6LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
A Doxycycline Hyclate Rodent Bait Formulation for Prophylaxis and Treatment of Tick-transmitted Borrelia burgdorferi (2008)

The prophylactic and curative potential of doxycycline hyclate formulated in a rodent bait at concentrations of 250 and 500 mg/Kg was evaluated in a murine model of Lyme borreliosis. Both bait formulations prevented tick-transmitted Borrelia burgdorferi infection in 100% of C3H/HeJ mice (N = 16), as well as cured acute, established infection in mice (N = 8) exposed to bait for 14 days. Spirochete infection was cleared in 88.9% to 100% of infected nymphs feeding on mice fed 250 and 500 mg/Kg antibiotic bait formulations, respectively. These data provide evidence for exploring alternative techniques to prevent transmission of Lyme disease spirochetes.
Acoustic Sounding in a Refracting Atmosphere (1972)

Acoustic refraction by atmospheric wind and temperature inhomogeneities affects the measurements of acoustic sounders in four ways: (a) It displaces the location of the scattering volume relative to its apparent location based on straight-line ray paths. (b) It alters the magnitude of the Doppler shift by changing the magnitude and direction of the wave vector at the scatterer. (c) It changes the scattering angle from that based on a straight-line geometry. (d) It introduces Doppler-shift contributions due to time variations of the atmospheric refractive index all along the sounding path. An idealized model of all these effects on bistatic soundings shows that most refractive corrections are small for present sounding geometries up to heights of about 1 km, but may need to be accounted for as sounding heights increase.
An Adaptometer for Preparation for Fluoroscopy (1951)

Every fluoroscopist has a method of determining when his eyes are dark-adapted; he wears goggles for a timed period, gauges his eyes by a light leak in the room, or perhaps switches the tube on and off until satisfied. Presented here is a low brightness adaptometer which will take the guess out of this chore. It consists of five self-luminous segments which are recessed into a rotating back plate. The luminosity is provided by phosphors excited by the beta radiation from the radioisotope, strontium90,3 and the inserts have the following surface brightnesses: A brighter red fixation point is located just above the window through which the luminous disks are exposed. The shutter is so situated that the fixation point is covered, or partly covered, as desired, when the window is open. The disks exhibit a certain degree of phosphorescence: accordingly the shutter should be kept closed in bright light. If exposure accidentally occurs, a 12-hour period should be allowed before use; otherwise spurious results will be obtained. The time required by six different observers to adapt to the various disks was as follows: In all the above readings the observers had previously been in sunlit interiors. Observer J. M. was red-green color-blind and wore correction lenses for myopia and astigmatism. Although with these he had 20/20 vision, he was unable to see disks 4 and 5. The variations among individuals exhibited here indicate the error in undergoing adaptation by the clock. This is further pointed up by the following readings in a single day by one observer who was exposed to various lightings before entering the darkroom. The instrument is essentially free from radiation hazard, there being no detectable reading when an exposed ionization chamber (Victoreen, low scale to 2.5 mr. per hour) was juxtaposed to the luminous sealed-in disks. Note: Since submission of this article we have found it advisable to use C14 instead of St90 in the phosphors, because of the longer half-life. Also developed is a smaller adaptometer containing two self-luminous segments only, and suitable for attachment to the fluoroscopic screen mount.
Amphetamine Metabolism in Amphetamine Psychosis<sup>*</sup> (1971)

A technique for the rapid estimation of amphetamine in human urine by means of gas chromatography has been devised in our laboratory. This method, which is both sensitive and quantitative, makes possible the detection of low levels of amphetamine in biological material. By this means, amphetamine excreted in human urine of amphetamine psychotics was estimated. Subjects included patients who became psychotic through self-administration of amphetamine and also those in whom psychosis was induced under controlled conditions. A correlation between levels of amphetamine and specific behavioral symptoms was observed. Patients receiving extreme doses of amphetamine were also studied for the formation of potential metabolites of amphetamine that might be psychotoxic. The implications of these findings in understanding amphetamine psychosis and psychotic symptomatology in general will be discussed.
Si-29 NMR spectroscopy of naturally-shocked quartz from Meteor Crater, Arizona: Correlation to Kieffer's classification scheme (1993)

We have applied solid state Si-29 nuclear magnetic resonance (NMR) spectroscopy to five naturally-shocked Coconino Sandstone samples from Meteor Crater, Arizona, with the goal of examining possible correlations between NMR spectral characteristics and shock level. This work follows our observation of a strong correlation between the width of a Si-29 resonance and peak shock pressure for experimentally shocked quartz powders. The peak width increase is due to the shock-induced formation of amorphous silica, which increases as a function of shock pressure over the range that we studied (7.5 to 22 GPa). The Coconino Sandstone spectra are in excellent agreement with the classification scheme of Kieffer in terms of presence and approximate abundances of quartz, coesite, stishovite, and glass. We also observe a new resonance in two moderately shocked samples that we have tentatively identified with silicon in tetrahedra with one hydroxyl group in a densified form of amorphous silica.
MISTRAL: Myopic deconvolution method applied to ADONIS and to simulated VLT-NAOS images (2000)

The monitoring of SN 1998bw through its second year has provided important new clues on the nature of this object. The late spectrum very much resembles the ones of other Type Ib/c supernovae. Hence, SN 1998bw can be tied to a class of objects we know fairly well. We confirm the large nickel mass required to power the optical radiation of this event, but find discrepancies by fitting the late spectrum with the models which were used to interpret the early phases. The implied energies are still unique for any supernova ever observed. The connection of SN 1998bw to GRB980425 is still unclear, but we do not expect to see any signature of the burst at these late phases. The radio observations have been linked to the γray burst and the relativistic expansion of material (Kulkarni et al. 1998, Li & Chevalier 1999). The X-ray emission from the GRB afterglow is coincident with the supernova as well (Pian et al. 1999). SN 1998bw remains a fascinating and puzzling object. The combination of two instruments and telescopes to follow SN 1998bw to late phases has been very useful. The 3.6-m/EFOSC2 provided the early coverage and only at the end was the supernova ‘handed’ to UT1/FORS1. We were therefore able to secure a spectrum about every month and could follow this object further than would have been possible with the 3.6-m. It is unlikely that there will be a third observing season for SN 1998bw. Unless the luminosity becomes constant, it will be too faint to be recovered. There are known processes that could lead to such a constant flux, e.g. interaction with the circumstellar material or input from the accretion on a black hole. We have been following several such objects already and SN 1998bw will be worth at least a check in the next few months.
Laser plasma sources for soft x-ray projection lithography (1993)

Compact laser plasma soft x-ray sources are under serious consideration for projection lithography. Current baseline designs for soft x-ray projection lithography systems place stringent performance and cost requirements on a laser plasma soft x-ray source. The x-ray source must meet specific criteria relating to x-ray fluence in the 13 nm region, the wavelength of preference for projection lithography, to output stability at high (kHz) repetition-rates, to continuous long term operation and to operating costs. Moreover the source must operate in a vacuum enclosure in close proximity to costly x-ray and optical elements which must remain in pristine condition, free from degradation by particulate and plasma emission emanating from the source. We discuss these requirements, and review experiments leading to the optimal design of a laser plasma soft x-ray source.
A myothermal analysis of the myosin crossbridge cycling rate during isometric tetanus in normal and hypothyroid rat hearts (1984)

Hypertrophied rabbit heart papillary muscles (thyrotoxicosis), with a high V1/V3 myosin isoenzyme ratio and contractile protein ATPase activity, have a high velocity of unloaded shortening and a decrease in the myothermal economy of isometric twitch force development and dissipation; in hypertrophied hearts (pressure overload) with a low V1/V3 isoenzyme ratio and ATPase activity, the converse was found to be true (Am J Cardiol 1979; 44:947-953; Fed Proc 1982; 41:192-198). In the present study the confounding problem of internal shortening, which takes place during force development and dissipation in the isometric twitch, is minimized by carrying out measurements of the rate of heat liberation during the plateau phase of tetanic force maintenance. The studies are further extended to another species (rat) where the V1/V3 myosin isoenzyme ratio is altered by treating the animal with propyl thiouracil added to the drinking water (PTU); here the contractile protein alteration occurs with myocardial atrophy rather than hypertrophy. High resolution, rapid temperature measurements are made in tetanically stimulated isometrically contracting rat heart papillary muscles from normal (high V1/V3 ratio) and PTU treated (low V1/V3 ratio) rats to assess the relationship between contractile protein performance (crossbridge cycling rate) in the intact muscle and that under controlled conditions in isolated myofibrils. In papillary muscles from the normal heart the crossbridge cycling rate (+/- SEM) during force maintenance was 6.53 (+/- 1.73) cycles/second compared with 3.13 (+/- 0.24) and 0.53 (+/- 0.17) cycles s-1 in the myofibril at high and low ionic strength, respectively.(ABSTRACT TRUNCATED AT 250 WORDS)
Snake robot uncovers secrets to sidewinders’ maneuverability (2015)

Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans the biological, physical, and social sciences.
Diagnosis of pancreatic tumors by endoscopic ultrasonography (2010)

Pancreatic tumors are highly diverse, as they can be solid or cystic, and benign or malignant. Since their imaging features overlap considerably, it is often difficult to characterize these tumors. In addition, small pancreatic tumors, especially those less than 2 cm in diameter, are difficult to detect and diagnose. For characterizing pancreatic tumors and detecting small pancreatic tumors, endoscopic ultrasonography (EUS) is the most sensitive of the imaging procedures currently available. This technique also provides good results in terms of the preoperative staging of pancreatic tumors. EUS-guided fine needle aspiration (EUS-FNA) has also proved to be a safe and useful method for tissue sampling of pancreatic tumors. Despite these advantages, however, it is still difficult to differentiate between benign and malignant, solid or cystic pancreatic tumors, malignant neoplasms, and chronic pancreatitis using EUS, even when EUS-FNA is performed. Recently, contrast-enhanced EUS with Doppler mode (CE-EUS) employing ultrasound contrast agents, which indicate vascularization in pancreatic lesions, has been found to be useful in the differential diagnosis of pancreatic tumors, especially small pancreatic tumors. However, Doppler ultrasonography with contrast-enhancement has several limitations, including blooming artifacts, poor spatial resolution, and low sensitivity to slow flow. Consequently, an echoendoscope was developed recently that has a broad-band transducer and an imaging mode that was designed specifically for contrast-enhanced harmonic EUS (CEH-EUS) with a second-generation ultrasound contrast agent. The CEH-EUS technique is expected to improve the differential diagnosis of pancreatic disease in the future. This review describes the EUS appearances of common solid and cystic pancreatic masses, the diagnostic accuracy of EUS-FNA, and the relative efficacies and advantages of CE-EUS and CEH-EUS along with their relative advantages and their complementary roles in clinical practice.