gebhart/patrepeval huggingface dataset:
THE SYNTHESIS OF SOME COMPOUNDS RELATED TO CUSCOHYGRINE (1954)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTTHE SYNTHESIS OF SOME COMPOUNDS RELATED TO CUSCOHYGRINEHENRY RAPOPORT, CURTIS G. CHRISTIAN, and GLENN SPENCERCite this: J. Org. Chem. 1954, 19, 5, 840–844Publication Date (Print):May 1, 1954Publication History Published online1 May 2002Published inissue 1 May 1954https://pubs.acs.org/doi/10.1021/jo01370a024https://doi.org/10.1021/jo01370a024research-articleACS PublicationsRequest reuse permissionsArticle Views88Altmetric-Citations7LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Pathogenesis of Pulmonary Edema by Alloxan (1957)

Alloxan causes pulmonary edema in anesthetized dogs by a local action in the lungs. Measurements of blood pressures, flow, vascular resistance and blood volume of intact and perfused lungs suggest that the initiation of edema is due to capillary congestion brought about by constriction of Pulmonary veins.
ABO Blood Type–Incompatible Kidney Transplantation and Access to Organs (2011)

These short-term results suggest that with a straightforward regimen, ABOi kidney transplantation is possible, acceptable results and graft function are obtainable, and access to kidney transplantation for those with a blood type-incompatible donor can be expanded.
Exponential intermolecular dynamics in optical Kerr effect spectroscopy of small-molecule liquids (1999)

Optical Kerr effect spectroscopy has been employed to study the behavior of six symmetric-top liquids (acetonitrile, acetonitrile-d3, benzene, carbon disulfide, chloroform, and methyl iodide) over a broad range of temperatures. In all of the liquids, an exponential intermolecular response is observed on a time scale of a few hundreds of femtoseconds. Comparison of the temperature dependence of the time scale of this relaxation with the viscosity and single-molecule and collective orientational times in the liquids suggests that the exponential relaxation arises from motional narrowing.
Medical Image Viewing on Multicore Platforms Using Parallel Computing Patterns (2010)

The parallel programming community has accumulated a significant amount of experience in the form of software patterns. Those patterns can be used in medical imaging applications on multicore platforms to improve startup time, runtime throughput, and algorithm reliability. As multicore processors become ubiquitous, we'll have increasing computing power at our disposal. It makes sense to exploit the improved performance in medical image applications since they tend to be computationally demanding, and parallel programming can help.
Hydrothermal activity in the Lau back arc basin: Plumes and hot fluids chemistry (1990)

During the French-German cruise Nautile(April-May 1989), 22 dives have been completed to understand the processes of seafloor arc formation associated with hydrothermal circulation along the volcanic Valu FA ridge. The CTD recordings, obtained in real time inside the Nautile, show the narrow relation between the geological structure and the temperature anomalies. The anomalies' amplitude and intensity permit the precise localization of hot hydrothermal discharges (Vai Lili site), diffuse (Hine Hina field) and nonperceptible inputs. Buoyant plumes producing entrainment and vertical transport up to 200 m above the seafloor are clearly identified with high CH{sub 4} (up to 4.4 {mu}l/L) and Mn (up to 90 {mu}mol/Kg) concentrations. For the first time, black smokers (240{degree} to 334{degree}C) were collected in a back arc environment. The samples (more than 90% pure hydrothermal fluid) have end member pH (1.8), among the lowest ever measured in oceanic hydrothermal fluids. The calculated end-member concentrations are enriched for Cl(0.65-0.75 mol/kg), Na (0.52-0.58 mol/Kg), Ca (30 mmol/Kg), K (55-67 mmol/Kg), Sr (123 {mu}mol/Kg), Rb (72-92 {mu}mol/kg), Li (690 {mu}mol/Kg). Compared with other hydrothermal waters, Si is slightly depleted (12-14 mmol/Kg), Fe (1.12.5 mmol/Kg), Mn (5.8-6.9 mmol/Kg), Cu (16-43 {mu}mol/Kg), Zn (1.2- 3 mmol/Kg) concentrations are high. The Vaimore » Lili site fluid concentrations in B (twice seawater), Ba (up to 40 {mu}mol/Kg), Zn (up to 3 mmol/Kg), Pb (up to 7 {mu}mol/kg). As (up to 11 {mu}mol/Kg) as well as the molar Cs/Rb and Fe/Mn ratios of respectively 0.024 and 0.2 are unexpected.« less
Pt Inclusion Compounds as Oxygen Reduction Catalysts in Polymer‐Electrolyte Fuel Cells (1998)

Pt inclusions in high‐specific‐area graphite (HS300, from Lonza) and Vulcan (XC‐72R, from Cabot) have been synthesized by the reduction of , salts intercalated in these hosts. These materials perform well as catalysts for the reduction of oxygen in polymer‐electrolyte fuel cells (PEFCs). After an activation time of 48 h during which the cathode is held at 0.5 V vs. the reference hydrogen electrode, it is found that catalysts based on Pt inclusions and commercial catalysts of the same Pt content and loading have similar mass and specific activities. However, in the same conditions, catalysts based on Pt inclusions perform better in the high‐current region than the commercial catalysts. It has been shown by X‐ray photoelectron spectroscopy analysis that, at the beginning of the activation time, a fraction of the Pt oxides and/or hydroxides present in the materials is reduced to Pt metal. This reduction improves the catalytic activities of the materials prepared in this study and also those of commercial catalysts. Further improvement is probably due to hydration of the catalyst layer and/or the washing out of insidious contaminants (e.g., chloride ions). Because higher current densities can be obtained with Pt included in graphite catalyst at a loading of 0.13 mg Pt/cm2 than with commercial Pt supported on Vulcan catalyst at a loading of 0.15 mg Pt/cm2, the use of cathode catalysts containing Pt inclusions is therefore a way of reducing the Pt loading at the cathode of PEFCs. However, a limitation of the new materials is the fact that the maximum amount of Pt that can be included in Vulcan is only about 5 wt %, whereas it is only 10 wt % in graphite.
The C6‐2B glioma cell P2Y<sub><i>AC</i></sub> receptor is pharmacologically and molecularly identical to the platelet P2Y<sub>12</sub> receptor (2001)

P2Y receptor activation in many cell types leads to phospholipase C activation and accumulation of inositol phosphates, while in blood platelets, C6-2B glioma cells, and in B10 microvascular endothelial cells a P2Y receptor subtype, which couples to inhibition of adenylyl cyclase, historically termed P2Y(AC), (P2T(AC) or P(2T) in platelets) has been identified. Recently, this receptor has been cloned and designated P2Y(12) in keeping with current P2 receptor nomenclature. Three selective P(2T) receptor antagonists, with a range of affinities, inhibited ADP-induced aggregation of washed human or rat platelets, in a concentration-dependent manner, with a rank order of antagonist potency (pIC(50), human: rat) of AR-C78511 (8.5 : 9.1)>AR-C69581 (6.2 : 6.0)>AR-C70300 (5.4 : 5.1). However, these compounds had no effect on ADP-induced platelet shape change. All three antagonists had no significant effect on the ADP-induced inositol phosphate formation in 1321N1 astrocytoma cells stably expressing the P2Y(1) receptor, when used at concentrations that inhibit platelet aggregation. These antagonists also blocked ADP-induced inhibition of adenylyl cyclase in rat platelets and C6-2B cells with identical rank orders of potency and overlapping concentration - response curves. RT - PCR and nucleotide sequence analyses revealed that the C6-2B cells express the P2Y(12) mRNA. These data demonstrate that the P2Y(AC) receptor in C6-2B cells is pharmacologically identical to the P2T(AC) receptor in rat platelets.
Recent advances with UNSW vanadium-based redox flow batteries (2009)

The vanadium redox flow battery pioneered by Skyllas-Kazacos et al. at the University of New South Wales (UNSW) is currently considered as one of the few electrochemical energy storage systems suitable for use in the large-scale utility applications that are emerging in response to the increasing global implementation of renewable energy technologies for the mitigation of greenhouse gas emissions. While the original all-vanadium redox flow battery (G1 VRF) has already been successfully implemented in a wide range of stationary field trials in Japan, U.S.A., Austria, Italy and Australia, further cost reduction has been needed for its widespread market up-take. In this paper, up to 80% efficiency is reported for the latest 5–10 kW G1 VRF battery stack employing low-cost stack materials that are expected to achieve the necessary cost structure for the majority of stationary energy storage applications. While the G1 VRF battery has shown high efficiencies and excellent cycle life, however, its low energy density has restricted its use in mobile applications. The new Generation 2 vanadium bromide redox battery (G2 V/Br) patented by UNSW in 2001 has been shown to potentially double the energy density of the G1 VRF battery, allowing mobile applications to be considered. In this paper, the performance of the G2 V/Br is presented at a range of temperatures and the use of complexing agents is shown to successfully bind any bromine produced during charging to prevent the formation of bromine vapours. Copyright © 2009 John Wiley & Sons, Ltd.
Lipidomic Analysis (2018)

The state-of-art in the lipidomic analysis is summarized here to provide the overview of available sample preparation strategies, mass spectrometry (MS)-based methods for the qualitative analysis of lipids, and the quantitative MS approaches for high-throughput clinical workflows. Major challenges in terms of widely accepted best practices for lipidomic analysis, nomenclature, and standards for data reporting are discussed as well.
Effect of lanthanum on the inotropic response of isoproterenol: role of the superficially bound calcium (1985)

Mammalian myocardial contractility is believed to be related to the amount of calcium contained in a highly labile superficial calcium pool. The purpose of this study was to determine the role of such sites in the positive inotropic effect of isoproterenol. Lanthanum, an ion that is restricted to the extracellular space and that displaces the superficially bound calcium, was selected as a tool for this investigation. In Langendorff preparations of the guinea pig heart, lanthanum decreased the basal contractility index (+dP/dtmax) in a concentration-dependent fashion (0.05-3 microM) and blocked the inotropic response of isoproterenol in a noncompetitive manner (0.25-3 microM). Three-micromolar lanthanum (i) reduced basal contractility and the maximum response to isoproterenol by 97 and 95%, respectively, (ii) had no significant effect (p greater than 0.05) on basal and isoproterenol-induced cyclic AMP levels, and (iii) had no effect on the Kd of [3H]nitrendipine binding, but reduced the Bmax by 31%. While 1 microM lanthanum reduced basal contractility and the maximum response to isoproterenol by 90 and 70%, respectively, it had no effect on [3H]nitrendipine binding. These results suggest that the effects of such low concentrations of lanthanum (less than or equal to 3 microM) are not related to a direct action on the calcium channels and are not mediated by an inhibition of isoproterenol stimulation of the enzyme adenylate cyclase. Therefore, one interpretation of these results suggests that superficially bound calcium is required for the inotropic response of isoproterenol.
Effect of the number structure and the quantity nature on secondary school students' proportional reasoning (2009)

status: Published
A Novel Method for Determining the Phase of T-Wave Alternans (2013)

We developed a method to quantify the temporal variability of the TWA phase. This method is expected to enhance the utility of TWA in predicting ventricular arrhythmias and sudden cardiac death and raises the possibility of using upstream therapies to abort a ventricular tachyarrhythmia before its onset.
Strategies for the Synthesis and Screening of Glycoconjugates. 1. A Library of Glycosylamines (1995)

A simple one-step procedure is found to be highly effective for the "functionalization" of glycodiversity. This study encompasses 50 unprotected mono- and oligosaccharides, which are subjected to Kochetkov aminations in saturated aqueous ammonium carbonate. The reaction allows for the stereo- and regioselective introduction of an amino group into all oligosaccharides tested, as well as into a great variety of monosaccharides including charged species. The resulting unprotected glycosylamines are stable compounds, and the inherent amino group provides a convenient site for chemoselective conjugation and modification as described in the following paper in this issue.
Biaryl Synthesis via Palladium-Catalyzed Aryne Multicomponent Coupling (2007)

Aryl iodides have been introduced as electrophiles in the three-component Heck coupling of arynes. Following optimization studies to favor three- versus two-component coupling, the reaction proceeds in good yield to afford a variety of functionalized biaryls.
Visualization of phosphotyrosine containing molecules within the detergent insoluble cell matrix of v-src transformed fibroblasts (1984)

The RSV oncogene v-src is known to transform host cells through the action of a single gene protein product (pp60src) endowed with tyrosine specific kinase activity. The nature and cellular localization of substrates of pp60src kinase are largely unknown. Detergent insoluble cell matrix was prepared by treating RSV-transformed mouse fibroblasts with the non-ionic detergent NP-40. These preparations, highly enriched in cytoskeletal proteins, when observed in the E M consisted mainly of a meshwork of filaments; fragments of plasma membrane and nuclear "ghosts" were also present. Antibodies against phosphotyrosine -previously shown to be reactive with protein phosphorylated at tyrosine residues- were prepared and affinity purified using a synthetic hapten (azobenzyl phosphonic acid, ABP). By means of the immunogold techniques applied to electron microscopy, phosphotyrosine containing molecules were found to be present in RSV transformed, but not in control fibroblasts. Gold particles were mostly bound to electron dense granular material associated with the filaments. These results are consistent with the idea that pp60src itself and some tyrosine phosphorylated proteins may be found among detergent-insoluble cell structures.
Surface EMG classification during dynamic contractions for multifunction transradial prostheses (2010)

High usability myo-controlled devices require robust classification schemes during dynamic contractions. Therefore, this study investigates the impact of the training data set on the performance of several pattern recognition algorithms during dynamic contractions. It is shown that combined with a threshold to detect the onset of the contraction, current pattern recognition algorithms used on static conditions can maintain relatively high classification accuracy on dynamic situations. Moreover, the performance of the pattern recognition algorithms tested improved by optimizing the choice of the training set. Finally, the results also showed that rather simple approaches for classification of time-domain features provide results comparable to more complex classification methods of wavelet features.
Mesitylene-Solvated Monolayers by Thermal Hydrosilylation (2011)

In this paper we show near-edge X-ray absorption fine structure (NEXAFS) analysis of monolayers that are formed by thermal hydrosilylation from 1-alkene diluted in mesitylene. The monolayers are not purely aliphatic as originally proposed. Instead the bound molecules have an alkenyl structure that is promoted by the presence of mesitylene. The double bonds are more prevalent than in our previous report for monolayers formed without mesitylene. Simulated NEXAFS spectra suggest that the double bonds are present in the form of 2-alkenyl moieties. The presence of double bonds impairs the use of these monolayers as dielectrics and enables their use for conductive interfaces.
Potential benefits of distributed PCM thermal (1989)

This report examines the benefits of passive thermal storage by means of phase change material (PCM) distributed throughout the wall and ceiling surfaces of a building, as would occur if the wallboard were impregnated with PCM. Surface heat transfer is expected to be adequate for thermal storage capacity up to 40-Btu/ft/sup 2/ of surface area. Sums of daily energy balances during the heating season indicate that use of PCM-impregnated wallboard with a 40-Btu/ft/sup 2/ capacity would provide adequate storage for direct gain systems with the largest practical window area in Denver, Boston, and Fort Worth. It is shown that distributed PCM thermal storage offers the opportunity to obtain several ton-hours of ventilative cooling per night throughout much of the US during July. 17 refs., 9 figs.
Durability of a Hybrid Air-Land Vehicle (2008)

A small hybrid vehicle has been developed and tested that is capable of flying, crawling, and transitioning between aerial and terrestrial locomotion modes. The Morphing Micro Air-Land Vehicle is a 16 inch wingspan craft proposed for advanced reconnaissance missions. Earlier versions of MMALV included several sources of low durability. Original prototypes relied on standard RC servos (modified for continuous rotation) as terrestrial locomotion drive motors. High impulse loads experienced during landing resulted in failure of these components, often after as few as two or three deployments. Battery containment was also an issue. During abrupt landings, the battery often became a destructive projectile within the fuselage. Another source of low durability was the method by which the motor was mounted to the fuselage. This was primarily an issue during the trimming process, during which crashes were sometimes unavoidable. Multiple improvements over the previous prototype are implemented that allow the vehicle to repeatedly survive the high impulse loading experienced during landing and even crashing. Compliance in each wheel-leg mitigates the peak level of the impulse load, and compliance in the terrestrial drive train limits the torque that is transmitted back to the drive motor. The custom-built drive train housing mates closely and is secured firmly to the fuselage. The housing also secures the battery. A motor nacelle designed into the fuselage allows for firm mounting of the motor, as well as reproducible placement and orientation of the motor. This both improved durability and decreased odds of crashing during trim flights. Improved wing designs were investigated to develop higher lift, thus allowing for lower cruising speed, which would reduce the loads experienced during landing.
Osteosarcoma in Hong Kong (1996)

Since 1984, the authors have treated 82 Chinese patients with sarcoma of bone. Of these patients, 58 had high grade osteosarcomas in the extremities. Of the 41 patients available for examination, the age range was 8 to 59 years, with a median of 17 years. Treatment consisted of preoperative and postoperative neoadjuvant chemotherapy, limb salvage surgery, or amputation. The overall survival rate was 62.9% at 2 years and 43% at 5 years. No significant difference was found in survival between the amputation and limb salvage groups, although local control was much better in the amputation group. There seemed to be better survival for patients who had a good response to preoperative chemotherapy, although the data did not reach statistical significance.
An Azimuth Measurement Algorithm for Mechanically Rotating Pulse Doppler Radars. (1995)

Abstract : For a mechanically rotating pulse Doppler radar having only a single main beam, an algorithm is presented that obtains an estimate of a target's azimuth angle using echo data obtained over a single coherent dwell. By removing the clutter and then cross-correlating the target echoes with a stored replica of the antenna pattern, azimuth angle measurement accuracies can be obtained within a fraction of a beamwidth. A Monte Carlo simulation was performed to determine the measurement error as a function of Signal-to-Noise Ratio (SNR) and target angular location within the radar's main beam. (KAR) P. 2
Compact analysis of 3D bipedal gait using geometric dynamics of simplified models (2009)

The large number of degrees of freedom in legged robots give rise to complicated dynamics equations. Analyzing these equations or using them for control can therefore be a difficult and non-intuitive task. A simplification of the complex multi-body dynamics can be achieved by instantaneously reducing it to an equivalent single inertial entity called the locked inertia or the composite rigid body inertia.
GETTING AHEAD OF THE GAME: QUANTIFYING THE VALUE OF LABORATORY TESTING PRIOR TO FULL-UP SYSTEM LEVEL (2018)

<title>ABSTRACT</title> <p>Program offices and the test community all desire to be more efficient with respect to testing but currently lack the analytical tools to help them fit early subsystem level testing into a framework which allows them to perform assessments at the system level. TARDEC initiated a Small Business Innovative Research (SBIR) effort to develop and deploy a system reliability testing and optimization tool that will quantify the value of subsystem level tests in an overall test program and incorporate the results into system level evaluations. The concept software, named the Army Lifecycle Test Optimization (ALTO) tool, provides not only the optimization capability desired, but also other key features to quickly see the current status, metrics, schedule, and reliability plots for the current test plan. As the user makes changes to the test plan, either by running the optimization or adjusting inputs or factors, the impacts on each of these areas is computed and displayed.</p>
ChemInform Abstract: 2,2-Dioxo-1H-thieno[3,4-c][1,2]thiazines. Synthesis and Some Reactions of a New Heterocycle. (2010)

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.