gebhart/patrepeval huggingface dataset:
Prevention of graft-versus-host disease in HLA-matched bone marrow transplantation for malignant diseases: a multicentric study of 62 patients using 3-pan-T monoclonal antibodies and rabbit complement. (1987)

In order to evaluate the effectiveness and reproducibility of T cell depletion in human leukocyte antigen (HLA)-matched bone marrow graft to prevent graft-v-host disease (GVHD), our multicentric study (nine different centers) investigated 62 consecutive patients with poor prognosis leukemia or hematosarcoma from June 1984 to November 1985. The data were updated October 1, 1986, and the mean follow-up was 18 +/- 4.3 months. T cells were depleted with a combination of 3-pan-T cell monoclonal antibodies (CD2 "D66"; CD5 "A50"; CD7 "I21") with a single incubation of rabbit complement (C'). The average number of T cells infused was 0.66 X 10(6) +/- 0.56/kg body weight. Twenty-six patients received chemoprophylaxis for GVHD, 16 received methotrexate, and ten received cyclosporin A. Only a single case of severe (greater than grade II) GVHD was observed, yet the incidence of graft failure was 19%. Factors that might have influenced the occurrence of graft failure appear to be the lack of radiotherapy in the conditioning regimen; the conditioning regimen itself (fractionated total body irradiation [TBI], 12 Gy, v single dose is better than TBI, 10 Gy, but still not statistically significant); and the age of the patients (high-risk after 30 years of age). In contrast, neither the number of nucleated cells reinfused nor the level of T cell depletion (provided the T cells were below critical numbers) seemed to have an influence, nor did chemoprophylaxis for GVHD or splenectomy in chronic granulocytic leukemia (CGL) patients. The survival of graft failure patients was very poor (one of 11; survival at 15 months of the initial graft). Thus, our study demonstrates the reproducibility and high effectiveness in preventing GVHD by immunodepletion of T cells in a large-scale multicentric assay, in which compliance with the protocol of immunodepletion was reasonably good. This study thus provides interesting clues to overcoming graft rejection.
Using complex seismic attributes to improve 4D visibility of fluids contact movement (2006)

Although much effort is still being directed to obtain quantitative information from time‐lapse seismic interpretation the success of this strategy depends on a variety of factors that are usually impossible to control such as signal to noise ratio or geologic requisites related with reservoir thickness or variations in capillary pressure that can cause variations in 4D tuning and impose difficulties to the use of AVO to quantify and separate variations induced by changes in saturation or pressure. But even qualitative information obtained from fluid contact movement can be of priceless value revealing unswept areas, or flow barriers that can not be determined without dynamic seismic information. The successful identification of contact movement that can be obtained from the simple subtraction of base and monitor surveys depend among other factors on the signal to noise ratio or tuning and that is the reason why complex attributes than conventional amplitudes have to be used to emphasize the contact variation that eventually can't be observed using simple amplitude subtraction.
Time-domain synthesis via Walsh functions (1975)

The paper deals with the application of Walsh functions to the time-domain-synthesis problem, i.e., the determination of a suitable internal structure for a system from its prescribed external (input/output) behaviour. The method is based on repeated integration, and a new operational matrix, which relates Walsh functions and their integrations, is defined. Examples of transfer-function and state-equation synthesis are used to illustrate the technique.
An Infrared Study of the C=N Stretching Frequency in N-Benzylideneaniline Derivatives (1967)

A series of 131 N-benzylideneaniline derivatives was prepared, and their infrared spectra were measured in the same conditions. Statistical tests showed that differences of substitution in benzene ring of benzylidene group affected acceptably on the region of C=N stretching absorption peak, but those in benzene ring of aniline group had smaller effect on it.
Ab initio simulation in extreme conditions (2005)

The study of materials properties under extreme conditions has made considerable progress over the past decade as a result of improvements in experimental techniques and advanced modeling methods. The availability of accurate models is crucial for analyzing results obtained in extreme conditions of pressure and temperature, where experimental data can be scarce. Among theoretical models, ab initio simulations are playing an increasingly important role because of their ability to predict materials properties without the need for any experimental input. Ab initio simulations also allow the exploration of materials properties in conditions that are unachievable using controlled experiments – such as, for example, the conditions prevailing in the cores of large planets. In that limit, they constitute the only quantitative model of condensed matter available today. We review the current status of ab initio simulations and discuss examples of recent applications in which numerical simulations have provided an essential complement to experimental data.
A Spatialization Method for Grain Yield Statistical Data: A Study on Winter Wheat of Shandong Province, China (2019)

Core Ideas Dividing the study area into subregions and classifying them improved winter wheat classification accuracy. Single‐phase Normalized Difference Vegetation Indices acquired on 6 March, 23 April, 25 May, and 29 June were the best variables for building the wheat yield spatialization model. The extraction accuracy of winter wheat area greatly impacted the spatialization of yield. The proposed model can provide a technical reference for producing high‐resolution crop yield distribution maps. Grain yield data based on administrative divisions (counties, cities, etc.) for statistics lack spatial information, which can be effectively solved by grain yield spatialization. This paper proposes a spatialization method for grain yield based on the Moderate Resolution Imaging Spectroradiometer (MODIS) Normalized Difference Vegetation Index (NDVI) time series data. The method was tested by taking winter wheat ( Triticum aestivum L.) in Shandong Province in China as an example. First, the classification and regression tree (CART) algorithm was trained to extract the winter wheat planting pixels in 2016. The average NDVIs of the different growing stages (returning green, jointing, heading, and milk ripening) were calculated from the MODIS NDVI time series data. The relationship between winter wheat yield and NDVI variables (including single‐phase NDVI and the average NDVI of different growing stages) was analyzed by univariate and multiple linear regressions. The NDVI variable with the highest correlation to winter wheat yield and the minimum root mean square error of the fitting equation were chosen as input to build the spatialization model. The results show that the classification accuracy of winter wheat estimated with the confusion matrix was 82.51% and that the average precision of planting acreage compared with county‐level statistical data was 87.64%. The average relative error of yield spatialization at the county level was 22.71%. The method developed in this paper is easy to operate and popularize, and it can provide a technical reference for producing high‐resolution crop yield distribution maps of long time series through spatialization.
Regulated nuclear translocation of the Mig1 glucose repressor. (1997)

Glucose represses the transcription of many genes in bakers yeast (Saccharomyces cerevisiae). Mig1 is a Cys2-His2 zinc finger protein that mediates glucose repression of several genes by binding to their promoters and recruiting the general repression complex Ssn6-Tup1. We have found that the subcellular localization of Mig1 is regulated by glucose. Mig1 is imported into the nucleus within minutes after the addition of glucose and is just as rapidly transported back to the cytoplasm when glucose is removed. This regulated nuclear localization requires components of the glucose repression signal transduction pathway. An internal region of the protein separate from the DNA binding and repression domains is necessary and sufficient for glucose-regulated nuclear import and export. Changes in the phosphorylation status of Mig1 are coincident with the changes in its localization, suggesting a possible regulatory role for phosphorylation. Our results suggest that a glucose-regulated nuclear import and/or export mechanism controls the activity of Mig1.
MTO catalyzed oxidation of aldehyde N,N-dimethylhydrazones with hydrogen peroxide: high yield formation of nitriles and N-methylene-N-methyl N-oxide (1998)

N,N-Dimethylhydrazones of aldehydes react with hydrogen peroxide at –50 °C in the presence of catalytic amounts of methyltrioxorhenium (MTO) to give in high yield the corresponding nitriles and N-methylene-N-methyl N-oxide.
PMD mitigation techniques and their effectiveness in installed fiber (2002)

The main building blocks of adaptive PMD compensators, the equalizer, the eye monitor for feedback signal generation, and the distortion tracking and adaptation logic for equalizer control will be reviewed with regard to system implementation. Equalizer units based on optical, optoelectronic, and electrical compensation schemes are discussed.
[Coxiella burnetii endocarditis on a mechanical valvular prosthesis. Apropos of 2 cases]. (1995)

The authors report two cases of prosthetic valve endocarditis due to Coxiella burnetii. The histories were chronic and complex suggesting an auto-immune disease: prolonged recurrent fever despite antibiotic therapy with a biological inflammatory syndrome whilst blood cultures remained negative. The first patient presented with prosthetic valve dehiscence and acute glomerulonephritis. The second patient had coagulation defects with prosthetic valve thrombosis, mesenteric adenopathy and congestive cardiac failure without prosthetic valve dysfunction. In suspected endocarditis with negative blood cultures, serological tests should be extended to intracellular pathogens difficult to identify and justifying specific and prolonged bactericidal therapy (fluoroquinolones, cyclines, rifampincine). Long-term serological surveillance is essential even when the outcome could have led to the termination of antibiotic therapy. Usually, antibiotic therapy provides a bacteriological cure, but treatment has to be continued for at least 3 years, and, in some patients, all their lives. Valve replacement is reserved for haemodynamic complications of the pathology which determine the ultimate prognosis.
Artificial Intelligence: A Guide to Intelligent Systems (2001)

From the Publisher:
Virtually all the literature on artificial intelligence is expressed in the jargon of commuter science, crowded with complex matrix algebra and differential equations. Unlike many other books on computer intelligence, this one demonstrates that most ideas behind intelligent systems are simple and straightforward. The book has evolved from lectures given to students with little knowledge of calculus, and the reader needs no prerequisites associated with knowledge of any programming language. The methods used in the book have been extensively tested through several courses given by the author. 

The book provides an introduction to the field of computer intelligence, covering 

rule-based expert systems,
fuzzy expert systems,
frame-based expert systems,
artificail neural networks,
evolutionary computation,
hybrid intelligent systems,
knowledge engineering,
data mining.


In a university setting the book can be used as an introductory course within computer science, information systems or engineering departments. The book is also suitable as a self-study guide for non-computer science professionals, giving access to the state of the art in knowledge-based systems and computational intelligence. Everyone who faces challenging problems and cannot solve them using traditional approaches can benefit
Aerospace sensor systems. (1968)

Aerospace sensor systems, discussing adaptive multimode sensors and multispectral sensing, electronic recognition of image components, laser radar and Raman scattering technique
Role of PPARγ in Regulating Adipocyte Differentiation and Insulin‐Responsive Glucose Uptake (1999)

Adipocyte differentiation is regulated by at least two families of transcription factors, CCAAT/enhancer binding proteins (C/EBPs) and peroxisome proliferator-activated receptors (PPARs). Induction of PPAR gamma gene transcription during the differentiation of preadipocytes into adipocytes in vitro occurs following an initial phase of cell proliferation and requires a direct involvement of C/EBP beta, C/EBP delta, and glucocorticoids. Ectopic expression of PPAR gamma in non-adipogenic, Swiss 3T3 fibroblasts promotes their conversion into adipocytes as indicated by the accumulation of lipid droplets and the induction of C/EBP alpha, aP2, insulin-responsive aminopeptidase (IRAP), and glucose transporter 4 (GLUT4) expression. These PPAR gamma-expressing Swiss cells also exhibit a high level of insulin-responsive glucose uptake that is comparable to that expressed in 3T3-L1 adipocytes. In contrast, PPAR gamma-expressing NIH-3T3 fibroblasts, despite similar lipid accumulation, adipocyte morphology, and aP2 expression, do not synthesize C/EBP alpha and fail to acquire insulin sensitivity. In Swiss 3T3 cells ectopically expressing PPAR gamma, the development of insulin-responsive glucose uptake correlates with C/EBP alpha expression. Furthermore, ectopic expression of C/EBP alpha in NIH-3T3 cells induces PPAR gamma expression and adipogenesis, but also restores insulin-sensitive glucose transport. These results suggest that although PPAR gamma is sufficient to trigger the adipogenic program, C/EBP alpha is required for establishment of insulin-sensitive glucose transport in adipocytes.
Epoxy Resins (2000)

The article contains sections titled: 1. Introduction 2. Types of Epoxy Resins 2.1. Bisphenol A Based Glycidyl Ethers 2.1.1. Preparation of Low Molecular Mass Bisphenol A Based Epoxy Resins 2.1.2. Preparation of High Molecular Mass Bisphenol A Based Epoxy Resins 2.1.3. Properties of Bisphenol A Based Resins 2.2. Other Glycidyl-Based Epoxy Resins 2.2.1. Brominated Bisphenol A Based Epoxy Resins 2.2.2. Phenol and Cresol Epoxy Novolacs 2.2.3. Glycidyl Ethers of Phenol-Aldehyde Adducts 2.2.4. Glycidyl Ethers of Phenol-Hydrocarbon Novolacs 2.2.5. Glycidyl Ethers of Aliphatic Diols 2.2.6. Aromatic Glycidyl Amines 2.2.7. Heterocyclic Glycidyl Imides and Amides 2.2.8. Glycidyl Esters 2.2.9. Fluorinated Epoxy Resins 2.3. Epoxidized Cycloaliphatic Olefins 2.4. Handling, Storage, and Transportation 2.5. Trade Names 3. Curing and Processing Technology 3.1. Multifunctional Curing Agents 3.1.1. Polyamines 3.1.2. Anhydrides 3.1.3. Miscellaneous Multifunctional Curing Agents 3.2. Homopolymerization of Epoxy Resins 3.3. Thermoset Properties 4. Uses 4.1. Protective Coatings 4.1.1. Unmodified Epoxy Resins 4.1.2. Modified Epoxy Resins 4.1.3. Powder Coatings 4.2. Structural Applications 4.2.1. Composites and Electrical Laminates 4.2.2. Casting Resins and Molding Compounds 4.2.3. Adhesives and Construction 5. Economic Aspects 6. Toxicology and Occupational Health 6.1. Bisphenol A Based Glycidyl Ethers 6.2. Phenol and Cresol Epoxy Novolac Resins
Multicarrier characterization method for extracting mobilities and carrier densities of semiconductors from variable magnetic field measurements (1993)

A simple, practical method is described to extract the carrier concentration and mobility of each component of a multicarrier semiconductor system (which may be either a homogeneous or multilayered structure) from variable magnetic field measurements. Advantages of the present method are mainly due to the inclusion of both the longitudinal and transverse components of the conductivity tensor and normalization of these quantities with respect to the zero-field longitudinal component of the conductivity tensor. This method also provides a simple, direct criterion by which one can easily determine whether the material under test is associated with a one-carrier or multicarrier conduction. The method is demonstrated for a simple one-carrier system [GaAs single-channel high-electron-mobility-transistor (HEMT) structure] and two multicarrier systems (an InGaAs-GaAs double-channel HEMT structure and two types of carriers present in an InGaAs single-channel HEMT structure). The analysis of the experimental data obtained on these samples demonstrates the utility of the method presented here for extracting carrier concentrations and mobilities in advanced semiconductor structures.
Management of Prostate Cancer (2000)

Prostate cancer remains the most common malignant tumor in elderly men. The National Cancer Institute estimated 210,000 new cases of prostate cancer in 1997. There is, however, no means of documenting the true incidence of prostate cancer because of the difficulty in detecting all cases. Even using yearly rectal exams, PSA determinations, and ultrasound-guided prostate biopsies, many cases are missed. Suffice it to say that prostate cancer is a widely occurring disease in men and early detection and treatment are extremely important. When I trained in Urology under Dr. Reed Nesbit at the University of Michigan from 1956 to 1959, the diagnosis of prostate cancer was made by a rectal examination and an acid phosphatase determination. If there was a small nodule in the prostate, then an anterior-posterior X-ray of the pelvis was obtained to look for possible bony metastases. If the acid phosphatase was normal and there was no evidence ofa bony metastasis, the prostate was exposed through the perineal approach and a biopsy of the nodule was obtained and sent for frozen section to Pathology to determine if it was indeed a cancer of the prostate. If the biopsy came back positive, the surgeon then proceeded to do a radical perineal prostatectomy. In those days, we usually did eight to ten radical perineal prostatectomies yearly. Many times the nodule that was biopsied was benign, and the incision was simply closed
Determination of Carboxylic Acids Present as Esters in Plasticizers and Polymers by Transesterification and Gas Chromatography (1965)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTDetermination of Carboxylic Acids Present as Esters in Plasticizers and Polymers by Transesterification and Gas ChromatographyStanley J. Jankowski and Patrick. GarnerCite this: Anal. Chem. 1965, 37, 13, 1709–1711Publication Date (Print):December 1, 1965Publication History Published online1 May 2002Published inissue 1 December 1965https://pubs.acs.org/doi/10.1021/ac60232a020https://doi.org/10.1021/ac60232a020research-articleACS PublicationsRequest reuse permissionsArticle Views132Altmetric-Citations19LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Simultaneous recording of skin blood pulsations at different vascular depths by multiwavelength photoplethysmography (2007)

A new technique for parallel recording of reflection photoplethysmography (PPG) signals in a broad spectral band (violet to near-infrared) has been developed, and its potential for assessment of blood microcirculation at various depths from the skin surface is discussed. PPG signals have been simultaneously detected at cw laser wavelength sets comprising 405, 532, 645, 807, and 1064 nm. Various signal baseline responses to breath holding and different shapes of the PPG pulses originated from the same heartbeat but recorded at different wavelengths have been observed, indicating a depth variety of the skin blood pulsation dynamics.
A Positive Education Program to Promote Wellbeing in Schools: A Case Study from a Hong Kong School (2018)

Students’ mental health is an alarming issue in Hong Kong, thereby increasing concern from psychologists, who attempted to implement positive education programs to equip students with skills to counteract mental health problems. This study followed the practice from positive psychology and conducted a Flourishing Life program based on the framework of the PERMA model in a secondary setting. The aims of the present paper are two-fold: to report the effort of the program and to evaluate the program’s effectiveness. A mixed-method sequential explanatory research design, including survey (n = 495) and subsequent two focus-group interviews (n = 8), was adopted to assess the program’s effectiveness. Results indicated that Forms Two and Three students (Grades 8 and 9) benefited more from the program than the Form One students (Grade 7). Overall, students reported that they had benefitted from the program. Findings provide supporting evidence to the whole-school approach program that operated effectively within the existing curriculum. This research may provide a direction for school curriculum leaders to promote students’ wellbeing by infusing essence from positive psychology to the school curriculum.
Improved performance and reliability for metal-oxide-semiconductor field-effect-transistor with fluorinated silicate glass passivation layer (2010)

The superior characteristics of the fluorinated HfO2/SiON gate dielectric are investigated comprehensively. Fluorine is incorporated into the gate dielectric through fluorinated silicate glass (FSG) passivation layer to form fluorinated HfO2/SiON dielectric. Fluorine incorporation has been proved to eliminate both bulk and interface trap densities due to Hf–F and Si–F bonds formation, which can strongly reduce trap generation as well as trap-assisted tunneling during subsequently constant voltage stress, and results in improved electrical characteristics and dielectric reliabilities. The results clearly indicate that the fluorinated HfO2/SiON gate dielectric using FSG passivation layer becomes a feasible technology for future ultrathin gate dielectric applications.