gebhart/patrepeval huggingface dataset:
Stability of growing front of YBa2Cu3O<i>x</i> superconductor in the presence of Pt and CeO2 additions (1995)

Distinctive microstructures of textured YBa2Cu3Ox (123) superconductors were examined by scanning electron microscopy and metallurgical microscopy. The samples were synthesized under a residual thermal gradient by using a modified melt textured growth on a Y2BaCuO5 (211) substrate. Also, the unidirectional solidification by a zone-melting method was performed to fabricate 123 superconducting bars up to 12 cm long placed on the 211 substrate in the horizontal arrangement, with a growth rate R=0.5 mm/h and a temperature gradient of G=20 °C/cm (G/R=400 °C h/cm2). A ramping temperature of 1 °C/h (GR) was applied in both syntheses. Typical defects running parallel to (001) planes associated with 211 trapped particles were observed (so-called platelet structure). Besides these, unusual defects were observed running parallel to (100) and (010) planes in textured 123+Pt superconductors, and interpreted as the result of an instability of the planar front in the presence of fine 211 particles. A theoretical model of planar interface stability confirms a strong dependence of stability region on the size of 211 particles in the melt.
Mechanism of Activation of Human Neutrophil Gelatinase B (1995)

Gelatinase B is a Zn(2+)- and Ca(2+)-dependent endopeptidase that is secreted from cells as an inactive proenzyme. The enzyme can be activated in vitro by organomercurial compounds and by trypsin. The role of Ca2+ in autoproteolytic processing initiated by 4-aminophenylmercuric acetate and trypsin and in catalytic activity of the activated enzyme was investigated by zymography and by kinetic analysis. Treatment of unglycosylated 57.5-kDa pro-gelatinase B with 4-aminophenylmercuric acetate (1 mM) in the absence of Ca2+ generated a 49-kDa inactive intermediate (E'), whereas a 41.5-kDa active species (E") was generated in the presence of Ca2+ (5 mM). Upon addition of Ca2+ to the reaction mixture of Ca(2+)-depleted E' or E" at 37 degrees C, E' showed a lag period in generation of the product as a function of time, but E" presented an immediate activity. The appearance of enzymatic activity of E' correlated with the generation of the E" species. NH2-terminal sequence analyses showed that E' and E" had the same NH2 termini, i.e. Met-75, suggesting that Ca(2+)-dependent removal of COOH terminus of E' is required for activation of the enzyme. Treatment of pro-gelatinase B with trypsin in the absence of Ca2+, led to degradation of the enzyme. In the presence of Ca2+, trypsin processed the pro-enzyme to a 40-kDa active species. In contrast to E", this active species did not require Ca2+ for activity. The Ca2+ dependence of E" activity was also abolished by treatment of the enzyme with trypsin. NH2-terminal sequence analysis indicated that amino acid residues 75-87 had been removed from the NH2 terminus of E" by trypsin, suggesting that these residues are responsible for the Ca(2+)-dependent activity of the enzyme. Removal of Ca2+ and catalytic Zn2+ inhibited the activities of both E" and trypsin-treated E". In the absence of Ca2+, either Zn2+, Co2+, Mn2+, or Cd2+ was able to restore the activity of trypsin-treated E". None of the divalent cations tested however, was able to stimulate the activity of E" in the absence of Ca2+. These experiments further suggest that binding of Ca2+ to E" or removal of the NH2-terminal residues of the enzyme by trypsin induces a conformational change in the protein and makes the active site of the enzyme accessible to various metal ions rendering the enzyme active.
Generating protein sequence tags by combining cone and conventional collision induced dissociation in a quadrupole time-of-flight mass spectrometer (2004)

The goal of proteomics research is to be able to identify and quantify the vast numbers of proteins within an organism or tissue. "Top-down" methods address this goal without the need for proteolytic digestion prior to mass analysis. We report here an approach for top-down protein identification that has been implemented on a commercially available, unmodified Qq-TOF mass spectrometer. Intact protein molecular ions first undergo cone fragmentation in the electrospray inlet. Conventional MS/MS is then performed on a mass selected cone fragment using CID in the Qq interface of the Qq-TOF mass spectrometer to generate a sequence tag through a pseudo-MS3 experiment. Seven proteins varying in molecular weight between 11 and 66 kDa were chosen to demonstrate applicability of method. After the molecular weight of the intact protein was determined, the cone voltage was varied to induce fragmentation. Cone fragment ions were then further dissociated using conventional CID, and the resulting MS/MS spectra were processed and analyzed for sequence tags. Sequence tags were easily identified from a MS/MS spectrum of a cone induced fragment ion both manually and through a de novo sequencing program included in the software associated with the mass spectrometer. Sequence tags were subjected to database searching using the PeptideSearch program of EMBL, and all protein sequence tags gave unambiguous search results. In all cases, sequence tags were found to originate from the n- and/or c-termini of the proteins.
Synthesis and properties of phosphorus-containing advanced epoxy resins. II (2000)

Two phosphorus-containing diacids were synthesized from 9,10-dihydro-9-oxa-10-phosphaphenanthrene 10-oxide (DOPO) and either maleic acid or itaconic acid and then reacted with diglycidyl ether of bisphenol A (DGEBA) to form two series of advanced epoxy resins. Reaction conditions, such as reaction time, temperature and catalyst, are discussed in this article. After curing with 4,4'-diaminodiphenyl sulfone (DDS), thermal properties of cured epoxy resins were studied using dynamic mechanical analysis (DMA) and thermal gravimetric analysis (TGA). The flame retardancy of cured epoxy resins was evaluated using a UL-94 measurement. © 2000 John Wiley & Sons, Inc. J Appl Polym Sci 78: 228–235, 2000
Potential correlations of dentogenic factors to the development of clinically verified fungus balls: A retrospective computed tomography–based analysis (2015)

Dentogenic factors regardless of type potentially correlate with the presence of maxillary sinus fungus ball. Unlike the overall presence of dentogenic factors, the particular dentogenic factors in an individual patient do not significantly influence the development of fungus balls. After diagnosis of dentogenic pathology in penetrated maxillary sinus floors, patients should be closely monitored and informed about their higher risk of developing a fungus ball.
Pergolide Mesylate: Its Effects on Circulating Anterior Pituitary Hormones in Man* (1981)

Pergolide mesylate is a synthetic ergoline with dopamine agonist properties. The endocrine profile was studied in a double blind crossover design in six normal males. Circulating PRL, TSH, GH, LH, FSH, and cortisol were measured in the basal state and after TRH (500 micrograms iv) administration at 4.5, 11.5, and 23.5 h after placebo or pergolide (100 micrograms orally). Pergolide caused suppression of basal PRL from 2-8 ng/ml to less than 2 ng/ml commencing 60 min after administration and persisting throughout the 23.5-h study period. For the three TRH tests, a suppression of peak PRL (mean +/- SEM) response to TRH of 54.6 +/- 5.1 vs. 1.9 +/- 0.5, 45.2 +/- 4.1 vs. 4.5 +2- 0.6, and 34.4 +/- 2.9 vs. 6.9 +/- 1.4 ng/ml, respectively, for placebo and pergolide was noted. Basal TSH levels were unaffected by pergolide, but after pergolide the peak TSH response to the first two TRH challenges was blunted (placebo vs. pergolide: 12.3 +/- 1.2 vs. 6.8 +/- 1.0 and 14.8 +/- 2.0 vs. 9.6 +/- 1.0, respectively); however, the third TSH response (9.8 +/- 1.1 vs. 9.3 +/- 1.2) was not blunted after pergolide. GH secretion was stimulated by pergolide with a consistent pulse observed within 60 min of pergolide administration and an enhancement in the number and amplitude of subsequent GH pulses throughout the 24-h period. Cortisol levels rose after pergolide and returned to levels seen on the control day at 16.5 h. FSH levels were unaffected but LH levels were lowered pergolide. Side effects including nausea, vomiting, and hypotension were observed in all subjects. Pergolide is a potent dopamine agonist with the anticipated endocrine profile and clinical effects; its long duration of actions offers promise of single daily dose therapy for hyperprolactinemia.
On the Development of Conductive Textile Antennas (2014)

UWB systems are becoming increasingly utilized due to their use in a variety of applications. Meanwhile, many advances have been achieved in the realm of conductive textiles. These textiles can be used as a sensing system or implemented wearable antennas. Combining these two applications is attractive for a number of reasons. First, wearable antennas constructed entirely from fabric offer a cost- effective, flexible solution when compared to rigid antennas. Second UWB technology is also attractive for body area network applications due to the low power operation and the inherent low radiated power in its system design. In our implementation accurately defined textile antennas have been developed using a laser machine with high precision cutting capabilities. The textile antennas are comprised of a conductive fabric layer that is laser defined and can be easily incorporated into uniforms and garments using a simple iron-on process. We have developed and present a monopole antenna design geared towards UWB applications. We show that these UWB textile antennas can be applied to localization systems and can provide accurate estimation of wearers location. Wide-band textile slot antennas have been developed too. The antennas are composed of three textile layers: the top and bottom are conducting layers and are precisely defined by a laser cutting machine, while the third layer is a textile dielectric layer sandwiched between these two conducting layers. A single, two-element and four-element array slot antennas have been developed and successfully tested. The developed antennas offer flexible, light-weight and bendable properties. The iron-on process allows for the fabric to be washed without losing its adhesion. The antenna fabrication and the capabilities of the laser precision technique and its extension to development of large area antenna arrays will be presented. Conductive textiles can also be implemented to meet the requirements of combat wound detection systems. Using these textiles, a fabric-based sensor can be developed to accurately detect and localize the bullets penetration.
Stable Ion Chemistry of Polycyclic Aromatic Hydrocarbons(PAHs); Modeling Electrophiles from Carcinogens (2004)

Active research on chemical carcinogenesis led to major advances in understanding the metabolic pathways and the events that ultimately lead to mutagenesis and carcinogenesis. Since polyarenes are most widely distributed class of human carcinogens in the environment, much of these efforts focused on understanding the mechanism of metabolic activation of polycyclic aromatic hydrocarbons (PAHs). In stable ion studies, protonation is used as a mimic reaction for generation of electrophiles from the PAHs, whereas α-PAH-substituted carbocations serve as models for carbocations formed by epoxide ring opening. Certain PAHs are direct acting mutagens, but many require metabolic activation via oxidative pathways before they can bind to DNA. In continuation, numerous other classes of PAHs and their substituted derivatives including biologically active analogs that possess twisted/nonplanar framework remain to be examined.
Enhanced invasion by enteroinvasive<i>Escherichia coli</i>of multinucleated HeLa cells (1987)

Enteroinvasive Escherichia coli (EIEC) preferentially invaded multinucleated HeLa cells which arose naturally in monolayer cultures at a low frequency. Data suggests that enhancement of the penetration step contributes to increased invasion. Treatment of HeLa cells with polyethylene glycol (PEG) led to cell fusion, and invasion of PEG-treated monolayers by EIEC increased an average of 7-fold compared to untreated HeLa cells. Large, multinucleated cells generated by PEG showed a striking accumulation of EIEC in cellular extensions. This study demonstrates that alteration of HeLa cell morphology results in increased invasion by EIEC.
Towards Ocean Grazer’s Modular Power Take-Off System Modeling:a Port-Hamiltonian Approach (2017)

This paper presents a modular modeling framework for the Ocean Grazer's Power Take-Off (PTO) system, which operates as an array of point-absorber type devices connected to a hydraulic system. The modeling is based on the port-Hamiltonian (PH) framework that enables energy-based analysis and control of the PTO system. Firstly, a modular model of a point-absorber hydraulic system, which represents the main building block of the PTO, is presented. The model consists of wave-mechanical and hydraulic subsystems that are interconnected with a transformer-type interconnection. Secondly, we show passivity of the point-absorber hydraulic element and the accumulation of potential energy, which is due to the novel pumping mechanism of the point-absorber. Finally, we illustrate these properties through simulation results.
Direct Measurement of the Spin-Orbit Interaction in a Two-Electron InAs Nanowire Quantum Dot (2007)

We demonstrate control of the electron number down to the last electron in tunable few-electron quantum dots defined in catalytically grown InAs nanowires. Using low temperature transport spectroscopy in the Coulomb blockade regime, we propose a method to directly determine the magnitude of the spin-orbit interaction in a two-electron artificial atom with strong spin-orbit coupling. Because of a large effective g factor |g(*)|=8+/-1, the transition from a singlet S to a triplet T+ ground state with increasing magnetic field is dominated by the Zeeman energy rather than by orbital effects. We find that the spin-orbit coupling mixes the T+ and S states and thus induces an avoided crossing with magnitude Delta(SO)=0.25+/-0.05 meV. This allows us to calculate the spin-orbit length lambda(SO) approximately 127 nm in such systems using a simple model.
Turbocharged spark ignition engine modelling and control strategy (2008)

This paper deals with the non-linear modelling and control of a turbocharged spark ignition engine. In the automotive industry, downsizing-based turbocharging is considered as a powerful technique to improve engine performances as fuel economy, pumping loss reduction to increase engine efficiency or driveability optimisation. This method is largely used for diesel engines. For gasoline engines, it is more complex in terms of control. In this work, a simplified control-oriented model is presented and validated using a Smart MCC three cylinders engine data. Then, based on this model, a fuzzy non-linear control law is calculated to achieve the fuel consumption and pumping losses reduction by setting the engine states to a given profile.
Distribution of contaminants used in automotive emission catalysts (1975)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTDistribution of contaminants used in automotive emission catalystsJohn L. Bomback, Mary A. Wheeler, Jack Tabock, and J. Daniel JanowskiCite this: Environ. Sci. Technol. 1975, 9, 2, 139–143Publication Date (Print):February 1, 1975Publication History Published online1 May 2002Published inissue 1 February 1975https://pubs.acs.org/doi/10.1021/es60100a001https://doi.org/10.1021/es60100a001research-articleACS PublicationsRequest reuse permissionsArticle Views51Altmetric-Citations10LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Anomalous Hall effect in thin films of<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mrow><mml:msub><mml:mrow><mml:mi mathvariant="normal">Pr</mml:mi></mml:mrow><mml:mrow><mml:mn>0.5</mml:mn></mml:mrow></mml:msub></mml:mrow></mml:math><mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mrow><mml:msub><mml:mrow><mml:mi mathvariant="normal">Sr</mml:mi></mml:mrow><mml:mrow><mml:mn>0.5</mml:mn></mml:mrow></mml:msub></mml:mrow></mml:math><mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mrow><mml:msub><mml:mrow><mml:mi mathvariant="normal">MnO</mml:mi></mml:mrow><mml:mrow><mml:mn>3</mml:mn></mml:mrow></mml:msub></mml:mrow></mml:math> (1997)

We report on the type and density of charge carriers obtained from Hall-effect measurements in the three different magnetic phases of ${\mathrm{Pr}}_{0.5}$${\mathrm{Sr}}_{0.5}$${\mathrm{MnO}}_{3}$ . The field dependence of the Hall resistivity has two contributions of opposite sign: one is related to skew scattering and dominates in low magnetic fields; the other one is due to the Lorentz-force contribution which prevails at higher fields. This second contribution corresponds to a temperature-independent carrier density in the order of 0.8 holes per chemical unit cell. The skew-scattering contribution is related to the susceptibility of the material and is maximum at the transition temperature from the ferro- to the antiferromagnetic state.
ChemInform Abstract: Reduction of gem‐Dibromocyclopropanes with Dialkyl Phosphonate and Amine. (1988)

Abstract The dialkyl phosphonates (II) are employed in the reduction debromination of the bicyclic geminal dibromide (I) to give mixtures of the endo‐ and exo‐bromides (III).
Development of a Dynamic Biomechanical Model for Load Carriage: Phase 1 Part A: Equipment Upgrades to Accommodate Dynamic Biomechanical Modeling (2005)

Part A of Phase I of the contract was to develop the instrumentation so that a dynamic biomechanical model could be developed. The specific objectives were: (a) to develop Fastrak(TM) software for relative pack person motion, (b) construct smaller strap force gauges, (c) build and calibrate a moment of inertia platform, (d) modify the Load Carriage compliance tester to automate two degrees of freedom and (e) create a full body mapping of mannequin. This report describes the purposes and outputs available from the pack person motion, describes the development, construction, calibration and protocol for use of smaller strap sensors and the moment of inertia platform, and the development and steps involved in modifying the LC compliance tester and the mannequin mapping. For the most part, tasks were developmental and construction based with no data analyses, other than to confirm the accuracy and precision of the instrumentation. This report deals only with Part A consisting of five sub parts of the contract. Part B involved changing the technical manuals based on the upgrades stated within this report. Part C of this contract is under separate cover and was to develop a long range plan and budget for dynamic biomechanical modeling. Part D was to assist with the NATO HFM Specialist Meeting entitled "Soldier Mobility: Innovations in Load Carriage System Design and Evaluation" held on 27-29 June 2000. Part D is described by the NATO RTO MP 56 Technical Proceedings Report entitled: "Soldier Mobility: Innovations in Load Carriage System Design and Evaluation."
Nitrification and denitrification by Thiosphaera pantotropha in aerobic chemostat cultures (1995)

Thiosphaera pantotropha has been reported to denitrify aerobically and nitrify heterotrophically. However, recent evidence has indicated that these properties (particularly aerobic denitrification) have been lost. The occurrence and levels of aerobic denitrification and heterotrophic nitrification by T. pantotropha in chemostat cultures have therefore been re-evaluated. Only low nitrate reduction rates were observed: the apparent nitrogen loss was of the same order of magnitude as the combined error in the calculated nitrogen consumption. However, 15N mass spectrometry revealed low aerobic denitrification rates (about 10% of the rates originally published by this group). Heterotrophic nitrification rates were about a third of previous observations. N2 and N2O were both produced from NH4+, NO3− and NO2−. Periplasmic nitrate reductase was present in aerobically grown cells.
The dynamics of the formation of the edge particle transport barrier at TJ-II (2011)

A large set of discharges with both spontaneous and forced confinement transitions at low electron density is studied at the stellarator TJ-II in different magnetic configurations. By means of a Bayesian technique, using reflectometry and interferometry, electron density profiles are reconstructed in the outer half of the plasma. A scanning heavy ion beam probe delivers information on the global evolution of the plasma potential. Langmuir probes are used to measure long-range correlations. Together, a comprehensive picture is obtained of the evolution of various key global plasma profiles and parameters across forward and backward transitions associated with the formation of an edge sheared flow layer. The impact of low-order rationals on the transition is elucidated.
Decreased apoptosis rate of alveolar lymphocytes (AL) in patients with stage I-IIA non-small cell lung cancer (NSCLC) (2014)

Background. NSCLC is characterized by unfavorable prognosis and low survival rate. The mechanisms of local immune suppression, including possible alterations of AL apoptosis has not been fully explored. Aim To evaluate the apoptosis rate of AL obtained from patients diagnosed with NSCLC. Methods Bronchoalveolar lavage (BAL) harvested from tumor-free lung region from NSCLC patients with diagnosis established by histopathology (squamous cell carcinoma, n=5 and adenocarcinoma, n=9, stage I-IIa) was analyzed for AL apoptosis by: 1) hypodiploidal cell analysis by flow cytometry (staining with propidium iodide), 2) TUNEL assay in cytological preparations. The control group consisted of subject diagnosed for ILD, in whom complete clinical investigation excluded finally any lung pathology. Results. In NSCLC patients, AL apoptosis rate tended to be lower as compared to respective controls. Statistical significance in adenocarcinoma smokers (0.2±0.3 vs 1.4±1.2% in flow cytometry, p Conclusions. AL in early NSCLC clinical stages seem to be protected from apoptosis. Together with enhanced AL percentage it may indicate relatively low level of lung immune suppression in this subgroup of NSCLC.
Effective Use of Simulations for the Teaching and Acquisition of Veterinary Professional and Clinical Skills (2005)

Simulation technology will feature prominently in this exciting, yet challenging, time for veterinary medicine. The profession is evolving to keep pace with rapid changes in clinical practice, scientific discovery, and educational strategy, while ensuring that it follows the public mandate to produce competent veterinarians. Among the challenges to meeting this educational goal are limitations-due to important issues such as animal welfare-on the availability of real patients for training. Drawing chiefly on the experience in human medicine, this article explores the use of simulations in veterinary medical education to provide safe and ethical alternative opportunities for learners to practice essential clinical and professional skills.