gebhart/patrepeval huggingface dataset:
Macromolecular Sequences in Systematic and Evolutionary Biology (1983)

Book Review| October 01 1983 Macromolecular Sequences in Systematic and Evolutionary Biology Macromolecular Sequences in Systematic and Evolutionary Biology. M. GOODMAN. Plenum PressNew York and London 1982, pp. 418, £45 JOHN WILLIAMS JOHN WILLIAMS Search for other works by this author on: This Site PubMed Google Scholar Biochem Soc Trans (1983) 11 (5): 607. https://doi.org/10.1042/bst0110607 Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter LinkedIn Cite Icon Cite Get Permissions Citation JOHN WILLIAMS; Macromolecular Sequences in Systematic and Evolutionary Biology. Biochem Soc Trans 1 October 1983; 11 (5): 607. doi: https://doi.org/10.1042/bst0110607 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsBiochemical Society Transactions Search Advanced Search This content is only available as a PDF. © 1983 Biochemical Society1983 Article PDF first page preview Close Modal You do not currently have access to this content.
The foundations of factor analysis (1984)

A new approach to factor analysis and related latent variable methods is proposed which is based on data reduction using the idea of Bayesian sufficiency. Considerations of symmetry, invariance and independence are used to determine an appropriate family of models. The results are expressed in terms of linear functions of the manifest variables after the manner of principal components analysis. The approach justifies some of the practices based on the normal theory factor model and lays a foundation for the treatment of nonnormal, including categorical, variables.
Magnesium and Hypertension (2012)

Hypertension remains the leading cause of cardiovascular disease (CVD) affecting approximately one billion individuals worldwide [1]. More than 72 million Americans, or nearly one in three adults, are estimated to have high blood pressure (BP), but only 35 % reach goal BP control [2]. Nearly 70 million more adults are at risk of developing prehypertension, and 90 % of adults will probably develop high BP by age 65 [3]. Hypertension is associated with an increased risk of morbidity and mortality from cerebrovascular accidents (CVA), coronary heart disease (CHD), congestive heart failure (CHF), and end-stage renal disease (ESRD). Over the past several years, there has been little change in BP diagnostic thresholds, treatment targets, or in treatment approaches. Due to its high prevalence, hypertension remains the most common reason for visits to physician’s offices and the primary reason for prescription drug use.
A CMOS low-power multiple 2.5-3.125-Gb/s serial link macrocellfor high IO bandwidth network ICs (2002)

This paper presents an 8-channel 2.5-3.125-Gb/s/ch serial link transceiver that achieves a total IO bandwidth of 20 Gb/s with a power consumption of less than 685 mW. The macrocell uses a shared phase-locked loop (PLL) architecture to minimize the potential noise coupling from the core digital part. The clock recovery is based on a new four-quadrant analog phase interpolator to overcome the phase discontinuity in a traditional analog quadrature-phase mixing interpolator. A dynamic amplitude control algorithm is used to maintain the loop stability while maximizing the interpolator's output. The receiver is constructed using half-rate integrate-and-dump devices to eliminate the requirement of quadrature clock and to improve the receiver sensitivity. A PMOS transmitter driver is used, so that its output voltage referenced to the ground is independent of power supply voltage. On-chip clock generation PLLs are implemented to provide global half-rate clocks. The prototype chip fabricated in a 0.16-μm CMOS process is under a 1.5-V power supply. The measured recovered clock jitter is 87 ps, peak-to-peak. The transmitter's output jitter is 58 ps, peak-to-peak. The active area of the macrocell is about 2 mm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> .
Operation of the Low-Energy Demonstration Accelerator: the proton injector for APT (2003)

We report preliminary test results for a 6.7-MeV, 100-mA cw radio-frequency quadrupole. During the time this structure was in design, fabrication, assembly, tuning, and installation, we tested a 75-keV proton injector, 350-MHz high-power RF systems, EPICS controls, diagnostics, beam stop, and other hardware in preparation for the 670 kW beam test. Initial LEDA RFQ beam operation has commenced. This paper summarizes work in the past year, concentrating on RFQ assembly, tuning, installation, high-power conditioning and initial beam operation. We include summaries of injector tests, 1.25-MeV RFQ-beam tests, beam-transport and beam-stop performance, and cavity resonance control. The technology being developed in this first section of the APT (accelerator production of tritium) linac is also appropriate for several other applications, including the transmutation of waste and medical isotope production.
Time spent with cats is never wasted: Lessons learned from feline acromegalic cardiomyopathy, a naturally occurring animal model of the human disease (2018)

These results demonstrate cats could be considered a naturally occurring model of acromegalic cardiomyopathy, and as such help elucidate mechanisms driving cardiovascular remodeling in this disease.
A PRIMER ON ANTENATAL TESTING FOR NEONATAL NURSES (2006)

A number of new antenatal testing tools are being used in obstetric practice to evaluate the clinical picture of the fetus in utero. Results of these tests may prompt transfer to a tertiary facility for delivery or further antenatal monitoring. Part 2 of this 2-part series will describe antenatal testing methods used to determine fetal well-being, as well as highlight the emerging developments in the field of fetal surveillance. The ability to interpret antenatal testing results may help the neonatal team triage to assure bed availability, and predict and provide appropriate staffing for new admissions, and is an important foundation for subsequent neonatal risks and clinical care.
Weighting Links Using Lexical and Positional Analysis in Web Ranking (2008)

Link analysis has been widely used to evaluate the importance of Web pages. Popular link analysis algorithms are mainly based on the link structure between pages. However, a Web page usually contains various links such as for navigation, decoration or nepotism, which are irrelevant to the topic of the Web page and can not reflect the actual voting relations between pages. In order to improve the performance of Web ranking, we bring out one filtering algorithm to recognize and eliminate these unrelated links using Content Lexical and Positional analysis. Experimental results on different Web domains show that our filtering model can efficiently detect the irrelevant links and effectively help to build a good link graph for the ranking calculation.
Improving Cell Recovery: Freezing and Thawing Optimization of Induced Pluripotent Stem Cells (2022)

Achieving good cell recovery after cryopreservation is an essential process when working with induced pluripotent stem cells (iPSC). Optimized freezing and thawing methods are required for good cell attachment and survival. In this review, we concentrate on these two aspects, freezing and thawing, but also discuss further factors influencing cell recovery such as cell storage and transport. Whenever a problem occurs during the thawing process of iPSC, it is initially not clear what it is caused by, because there are many factors involved that can contribute to insufficient cell recovery. Thawing problems can usually be solved more quickly when a certain order of steps to be taken is followed. Under optimized conditions, iPSC should be ready for further experiments approximately 4-7 days after thawing and seeding. However, if the freezing and thawing protocols are not optimized, this time can increase up to 2-3 weeks, complicating any further experiments. Here, we suggest optimization steps and troubleshooting options for the freezing, thawing, and seeding of iPSC on feeder-free, Matrigel™-coated, cell culture plates whenever iPSC cannot be recovered in sufficient quality. This review applies to two-dimensional (2D) monolayer cell culture and to iPSC, passaged, frozen, and thawed as cell aggregates (clumps). Furthermore, we discuss usually less well-described factors such as the cell growth phase before freezing and the prevention of osmotic shock during thawing.
Chromatographic isolation of the original constituents of natural waxes. The composition of ouricuri wax (1960)

Summary A chromatographic method was developed which separated a known mixture of alleged wax constituents into four groups, viz. , dotriacontane, octadecyl stearate and stearone, octadecanol, and stearic acid on especially prepared alumina. This adsorbent, when prepared fresh, did not give a satisfactory separation of spermaceti wax. On re‐use after regeneration by exhaustive washing with methanol and water, spermaceti wax was resolved into esters (95.4%), alcohols (2.6%), and acids (1.2%). A resolution of ourieuri wax into four major classes (nine fractions) was obtained on alumina (M. Woelm, aniontrophie, pII4) of lesser adsorptive activity than the two previous preparations. Two of the latter fractions were further resolved on silica gel. There is a priori evidence that the constitutents of natural plant waxes do not conform rigidly to the pattern of mixtures of simple normal esters. An estimated composition of ouricuri wax (in per cent) is hydrocarbons 1.3, simple esters 23.5, hydroxy‐mono‐esters 22.4, hydroxy‐di‐esters 17.2, hydroxy‐aeidie‐poly‐esters 5.4, free acids 8.7, free alcohols 3.0, resins 14.8, moisture 1.4, and ash 0.4.
A Single-Loop SS-LMS Algorithm With Single-Ended Integrating DFE Receiver for Multi-Drop DRAM Interface (2011)

A 3.8 Gb/s multi-drop single-ended integrating DFE (IDFE) receiver is implemented in a 0.18 um CMOS by using a single-loop LMS-algorithm to find the DFE coefficients automatically. Initially, a preamble input data pattern ('1101') is applied to the main IDFE circuit to determine the DFE coefficients, while a fixed input data pattern ('1111') is applied to the replica IDFE circuit. The difference between the outputs of the two IDFE circuits is used in the feedback loop to determine the DFE coefficients. The reference voltage (Vref) of preamplifier is generated inside chip by a Vref loop to reduce the effect of the external noise and the input offset voltage of preamplifier and IDFE circuits and also to track the mid-level of the input data swing in spite of process variations of TX chips. An integrating deskew scheme with a minimum overhead is introduced. 2-drop and 4-drop DRAM channels are tested. The maximum data rate was increased from 1.0 Gb/s to 2.6 Gb/s by DFE in the heavily loaded 4-drop interface, from 3.5 Gb/s to 3.8 Gb/s by DFE in the 2-drop interface.
Two new Entheus from Ecuador and Peru (Lepidoptera: Hesperiidae: Pyrginae). (1997)

Two new species of Entheus are described: Entheus latebrosus n. sp. , from Ecuador and Peru, and Entheus curvus n. sp ., from Peru
Protection of computer systems from computer viruses: ethical and practical issues (2002)

without fee all or part of this material is granted provided that the copies are not made or distributed for direct commercial advantage, the CCSC copyright notice and the title of the publication and its date appear, and notice is given that copying is by permission of the Consortium for Computing Sciences in Colleges. To copy otherwise, or to republish, requires a fee and/or specific permission.
<i>In Vitro</i> Pharmacokinetic/Pharmacodynamic Models in Anti-Infective Drug Development: Focus on TB (2010)

For rapid anti-tuberculosis (TB) drug development in vitro pharmacokinetic/pharmacodynamic (PK/PD) models are useful in evaluating the direct interaction between the drug and the bacteria, thereby guiding the selection of candidate compounds and the optimization of their dosing regimens. Utilizing in vivo drug-clearance profiles from animal and/or human studies and simulating them in an in vitro PK/PD model allows the in-depth characterization of antibiotic activity of new and existing antibacterials by generating time–kill data. These data capture the dynamic interplay between mycobacterial growth and changing drug concentration as encountered during prolonged drug therapy. This review focuses on important PK/PD parameters relevant to anti-TB drug development, provides an overview of in vitro PK/PD models used to evaluate the efficacy of agents against mycobacteria and discusses the related mathematical modeling approaches of time–kill data. Overall, it provides an introduction to in vitro PK/PD models and their application as critical tools in evaluating anti-TB drugs.
Storage Area Networks and The High Performance Storage System (2002)

The High Performance Storage System (HPSS) is a mature Hierarchical Storage Management (HSM) system that was developed around a network-centered architecture, with client access to storage provided through third-party controls. Because of this design, HPSS is able to leverage today's Storage Area Network (SAN) infrastructures to provide cost effective, large-scale storage systems and high performance global file access for clients. Key attributes of SAN file systems are found in HPSS today, and more complete SAN file system capabilities are being added. This paper traces the HPSS storage network architecture from the original implementation using HIPPI and IPI-3 technology, through today's local area network (LAN) capabilities, and to SAN file system capabilities now in development. At each stage, HPSS capabilities are compared with capabilities generally accepted today as characteristic of storage area networks and SAN file systems.
Calcium Hydroxide and Potassium Nitrate as Desensitizing Agents for Hypersensitive Root Surfaces, (1977)

The purpose of this investigation was to evaluate calcium hydroxide and potassium nitrate individually as densensitizing agents for hypersensitive root surfaces. The apparatus used in the experiment to measure hypersensitivity was (a) a thermo-electric stimulating device to measure hot and cold stimulation quantitatively and (b) a mechanical stimulating device to measure scratch stimulation quantitatively. The conclusions drawn from the study were: 1. Calcium hydroxide was more consistently effective in decreasing sensitivity then was potassium nitrate or the control. 2. Calcium hydroxide as compared to the control was statistically (99% level of significance) more effective in reducing sensitivity to mechanical, hot and cold stimulation immediately and at the conclusion of the experiment (3 months). 3. It appears that calcium hydroxide could be used as a desensitizing agent initially following periodontal surgery to reduce pain from hypersensitive roots in order that proper oral hygiene could be reestablished.
Moulded piezoelectric transducers using polar polymers (1978)

Polar polymer such as PVC, PVF and PVF2 show strong piezoelectric activity after being stretched and poled. They were used up to now in plane or cylindrical configurations. We show that such polymers can be moulded and poled, which constitutes a new generation of piezoelectric transducers. Example is given of a high range loudspeaker using a moulded PVC film.
Micromechanical voltage controlled switches and circuits (1978)

Micromechanical devices and circuits have been fabricated in which a thin (3500 Å) metal-coated SiO <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</inf> membrane, ∼76 µm long, is suspended over a 7 µm deep well anisotropically etched in oriented crystalline silicon. Additional raised structures formed by gold plating are attached to the membrane such that an electrical switching function is accomplished when the membrane is electrostatically deflected downward into the well. Switching times of less than 40 µsec have been observed at deflection voltages of about 60 V in this preliminary design The very high off/on state impedance ratios of these devices suggest applications in the areas of analog signal switching and charge storage related to optical image storage. Fabrication and operation of these devices and circuits are described, and more complex implementations of this new technology are discussed.
Elementary Steps in T Cell Receptor Triggering (2012)

The mechanism by which antigen binding to the T cell antigen receptor (TCR) generates intracellular signaling, a process termed TCR triggering, is incompletely understood. A large body of experimental evidence has implicated multiple biophysical/biochemical effects and multiple molecules in the process of TCR triggering, which likely reflect the uniquely demanding role of the TCR in recognizing diverse antigenic ligands. In this perspective, I propose that breaking down the process of TCR triggering into tractable elementary steps may be a useful approach in building mechanistic TCR triggering models. Once these elementary steps are understood, they can be recombined to build a unified model of TCR triggering.
HUMAN FACTORS AND MODELS (1983)

Human-factors engineering, which embodies the basic assumption that man should be considered as a major component of a system and not merely an operator of the system once it has been developed, has as its main concern the design of efficient and safe man/machine systems. Design Work Study technology, and construction models for studying man/machine/software interfaces, are important tools in the design of such systems. The Authors discuss human-factors engineering and construction models with particular reference to ship systems for the US Navy, and describe some of the procedures used to develop operational concepts for use in conjunction with scale models or full-size mock-ups in the study of space allocations and machinery arrangements. Main headings of the Paper include:- Human Performance Requirements ; Operational Stations Book; Space Configuration Design ; Personnel Sub-systems.
A fast overcurrent protection scheme for GaN GITs (2017)

A fast overcurrent protection scheme was developed for GaN gate injection transistors (GITs), harnessing the relationship between the externally measured vgs and id in steady-state operation. This relationship has been characterized in both static and dynamic testing over a wide range of operating conditions, and a circuit has been constructed to implement this control scheme. The circuit uses analog components to integrate the protection feature into a commercially available GIT gate driver. The scheme was experimentally verified in a double pulse test setup for experimental verification, and its total fault response time was recorded at less than 70 ns, with 400 V dc bus and a 30 A threshold. Compared with conventional desaturation protection, which detects faults based on drain voltage rather than gate voltage, the proposed scheme offers benefits in terms of speed, temperature invariance, flexibility in threshold selection, and minimal impact on the GIT's normal switching behavior.
Carbon anode materials based on melamine resin (1998)

We have obtained carbon anode materials based on a melamine resin. Through elemental analysis, X-ray powder diffraction, BET measurement and X-ray photoelectron spectroscopy, the effects of heat-treatment temperature and doping of phosphorus were investigated. Temperature affects mainly the nitrogen content, the size of graphite crystallites and the number of micropores in the carbons, and thus their reversible capacity changes with temperature. The highest reversible capacity occurs at 600 °C. The addition of phosphoric acid can affect the carbon structure and relative content of graphene nitrogen. Its behaviour changes with temperature. Only at high temperature, can the doped phosphorus favour the enhancement of reversible capacity.
Opportunistic Buffered Decode-Wait-and-Forward (OBDWF) Protocol for Mobile Wireless Relay Networks (2011)

In this paper, we propose an opportunistic buffered decode-wait-and-forward (OBDWF) protocol to exploit both relay buffering and relay mobility to enhance the system throughput and the end-to-end packet delay under bursty arrivals. We consider a point-to-point communication link assisted by K mobile relays. We illustrate that the OBDWF protocol could achieve a better throughput and delay performance compared with existing baseline systems such as the conventional dynamic decode-and-forward (DDF) and amplified-and-forward (AF) protocol. In addition to simulation performance, we also derived closed-form asymptotic throughput and delay expressions of the OBDWF protocol. Specifically, the proposed OBDWF protocol achieves an asymptotic throughput ΘL(\log_2 K) with ΘL(1) total transmit power in the relay network. This is a significant gain compared with the best known performance in conventional protocols (ΘL(\log_2 K) throughput with ΘL(K) total transmit power). With bursty arrivals, we show that both the stability region and average delay of the proposed OBDWF protocol can achieve order-wise performance gain ΘL(K) compared with conventional DDF protocol.
FcaNet: Frequency Channel Attention Networks (2020)

Attention mechanism, especially channel attention, has gained great success in the computer vision field. Many works focus on how to design efficient channel attention mechanisms while ignoring a fundamental problem, i.e., channel attention mechanism uses scalar to represent channel, which is difficult due to massive information loss. In this work, we start from a different view and regard the channel representation problem as a compression process using frequency analysis. Based on the frequency analysis, we mathematically prove that the conventional global average pooling is a special case of the feature decomposition in the frequency domain. With the proof, we naturally generalize the compression of the channel attention mechanism in the frequency domain and propose our method with multi-spectral channel attention, termed as FcaNet. FcaNet is simple but effective. We can change a few lines of code in the calculation to implement our method within existing channel attention methods. Moreover, the proposed method achieves state-of-the-art results compared with other channel attention methods on image classification, object detection, and instance segmentation tasks. Our method could consistently outperform the baseline SENet, with the same number of parameters and the same computational cost. Our code and models will are publicly available at https://github.com/cfzd/FcaNet.
Be Prepared (1974)

This publication contains reprint articles for which IEEE does not hold copyright. Full text is not available on IEEE Xplore for these articles.
Still image coding using predictive tree-VQ with sub-band decomposition (2002)

The combination of a linear-predictive still-image coding scheme with tree encoding and vector quantization (predictive tree-VQ, PTVQ) is applied to subband decomposed images. PTVQ allows the use of large codeword lengths and produces good image quality at bit rates around 0.3 b/pixel. Schemes with and without local bit-rate adaptation are studied. All combinations of PTVQ and subband coding (SBC) show good performance with regard to signal-to-noise-ratio (SNR) and perceptual quality criteria and outperform the original PTVQ as well as simple SBC-DPCM (differential pulse-code modulation) schemes, even at rates as low as 0.2 b/pixel.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>