gebhart/patrepeval huggingface dataset:
Growth of <i>Salmonella enterica</i> in foliar pesticide solutions and its survival during field production and postharvest handling of fresh market tomato (2013)

The study points out the importance of the microbiological quality of foliar contact water as a critical point to prevent contamination of fruits and vegetables from early stages of field production.
Thrombotic risk factors for atherosclerosis (1996)

Whitaker Cardiovascular Institute, Evans Department of Medicine and Department ol Biochemistry. Boston University School ot Medicine, Boston, Massachusetts, USA.
Mitochondrial targeted osmium polypyridyl probe shows concentration dependent uptake, localisation and mechanism of cell death (2019)

A symmetric osmium(ii) [bis-(4'-(4-carboxyphenyl)-2,2':6',2''-terpyridine)] was prepared and conjugated to two mitochondrial-targeting peptide sequences; FrFKFrFK (r = d-arginine). The parent and conjugate complexes showed strong near infra-red emission centred at λmax 745 nm that was modestly oxygen dependent in the case of the parent and oxygen independent in the case of the conjugate, attributed in the latter case, surprisingly, to a shorter emission lifetime of the conjugate compared to the parent. Confocal fluorescence imaging of sub-live HeLa and MCF 7 cells showed the parent complex was cell impermeable whereas the conjugate was rapidly internalised into the cell and distributed in a concentration dependent manner. At concentrations below approximately 30 μmol, the conjugate localised to the mitochondria of both cell types where it was observed to trigger apoptosis induced by the collapse of the mitochondrial membrane potential (MPP). At concentrations exceeding 30 μmol the conjugate was similarly internalised rapidly but distributed throughout the cell, including to the nucleus and nucleolus. At these concentrations, it was observed to precipitate a caspase-dependent apoptotic pathway. The combination of concentration dependent organelle targeting, NIR emission coincident with the biological window, and distribution dependent cytotoxicity offers an interesting approach to theranostics with the possibility of eliciting site dependent therapeutic effect whilst monitoring the therapeutic effect with luminescence imaging.
The Yenan Way in Revolutionary China. By Mark Selden. Cambridge: Harvard University Press, 1971. xi, 278 pp. Bibliography, Glossary, Index. $10.00. (1972)

An abstract is not available for this content so a preview has been provided. Please use the Get access link above for information on how to access this content.
ChemInform Abstract: Novel 4‐Substituted 4,5‐Dihydro‐3H‐(8‐amino‐6‐oxo)pyrrolo(3,4‐f)(1,3,5) triazepines from Z‐N2‐(2‐Amino‐1,2‐dicyano)formamidine and Carbonyl Compounds. (1993)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Immunolocalization of proteins specific for <i>adhaerens</i> junctions in human gingival epithelial cells grown on differently processed titanium surfaces (1991)

The localization of desmoplakins 1 and 2 (DP 1&2), components of desmosomes, vinculin, and actin, was studied in gingival epithelial cells grown on cell culture glass and on titanium plates with various surface topography. The results showed that epithelial cells attached and spread more readily on smooth than on rough, sandblasted titanium surfaces. Moreover, the cells appeared to develop more granular DP 1&2 immunoreactivity at their ventral surfaces when grown on smooth or etched titanium as compared to glass. In cells grown on sandblasted titanium surfaces, DP 1&2-specific immunoreactivity was primarily located at cell-cell contacts. Cells grown on smooth titanium surfaces harbored a fine network of actin filaments with apparent cell-to-cell organization. Vinculin was confined to cell-cell contact areas. No vinculin-containing focal adhesions could be detected, suggesting that the cells adhere either by means of close contacts, extracellular matrix contacts, or by means of hemidesmosomes. The findings suggest that smooth of finely grooved titanium surfaces could be optimal in maintaining the adhesion and specialized phenotype of gingival epithelial cells.
A Potential Blood Substitute from Carboxylic Dextran and Oxyhemoglobin.: III. Evaluations by Perfusion of Normal and Ischemic Guinea-Pig Heart (1992)

Hemodynamic parameters of six groups of guinea-pig hearts were studied by the working heart technic of Neely. Three groups were respectively perfused with: Krebs-Henseleit, purified native hemoglobin 1gm/dl and hemoglobin conjugated to dextran benzene tetracarboxylate 1 gm/dl. Three other groups were perfused under the same conditions except that after 30 mn of perfusion, 10 mn of total ischemia were produced followed by 30 mn of reperfusion with the previous solutions. All solutions contained 10 g/l of BSA. Hearts perfused with Hb solutions without ischemia or after ischemia show better parameters than with Krebs-Henseleit. These observations suggest that contrary to previously published results, purified Hb and more, dextran-BTC-Hb appear to be perfusable and are less deleterious for heart than saline without hemoglobin.
Pre-Clinical Blocking of PD-L1 molecule, which expression is down regulated by NF-κB, JAK1/JAK2 and BTK inhibitors, induces regression of activated B-cell lymphoma (2018)

Abstract Escape from immune control must be important in the natural course of B-cell lymphomas, especially for those with activation of NF-κB. The pre-clinical L.CD40 transgenic mouse model is characterized by B-cell specific CD40 signaling responsible for NF-κB continuous activation with a spleen monoclonal B-cell tumor after one year in 60% of cases. L.CD40 tumors B-cells expressed high levels of PD-L1. This expression was dependent on activation of either NF-κB, JAK1/JAK2 or BTK pathways since ex vivo treatment with the inhibitory molecules PHA-408, ruxolitinib and ibrutinib led to decrease of its expression. Treatment of L.CD40 lymphomatous mice with an anti-PD-L1 monoclonal antibody induced tumor regression with decreased spleen content, activation and proliferation rate of B-cells as well as a marked increase in T cell activation, as assessed by CD62L and CD44 expression. These results highlight the interest of therapies targeting the PD-1/PD-L1 axis in activated lymphomas with PD-L1 expression, with possible synergies with tyrosine kinase inhibitors.
Method for acceleration of logic simulations (2002)

We present a method for acceleration of logic simulations. The logic simulation is mainly used to detect malfunctions in the logical design phase. As the size of logical circuits grows, acceleration of the logic simulation becomes increasingly required. Several acceleration methods have been presented for this purpose. The outstanding feature of our method is that it accelerates the simulation speed in accordance with the dynamic behaviours of target circuits. A global dynamic behaviour is predicted to realize this feature, through the investigation of the relationship among gates in the early stage of the simulation. Using the relationships, a logic simulation is accelerated by a process called "grouping". We have confirmed that the dynamic information of the circuits accelerates logical simulation by the evaluation system.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Impact of out-of-cell interference on strongest-users-only CDMA detectors (2003)

A randomly spread direct sequence code division multiple access (DS-CDMA) multi-cell system operating in flat fading is considered. The model adheres to A.D. Wyner's infinite linear cell-array setting (see IEEE Trans. Inform. Theory, vol.40, p.1713-27, 1994), where only adjacent-cell interference is present, and characterized by a single parameter, 0/spl les//spl alpha//spl les/1. Users are assumed to employ equal rates and transmit powers. The receiver ranks the intracell users according to their received powers, and decodes only the subset that can be reliably decoded. Confining the discussion to asymptotic analysis (in terms of number of users and processing gain), we study four multiuser detection strategies, differing in the amount and type of information available to the receiver with respect to (both intracell and out-of-cell) interfering users. The total capacities under outage constraint, derived as functions of the fraction of users that cannot be reliably decoded (equivalent to the "outage probability"), are analyzed and compared.
Caspase-2 impacts lung tumorigenesis and chemotherapy response in vivo (2014)

Caspase-2 is an atypical caspase that regulates apoptosis, cell cycle arrest and genome maintenance, although the mechanisms are not well understood. Caspase-2 has also been implicated in chemotherapy response in lung cancer, but this function has not been addressed in vivo. Here we show that Caspase-2 functions as a tumor suppressor in Kras-driven lung cancer in vivo. Loss of Caspase-2 leads to enhanced tumor proliferation and progression. Despite being more histologically advanced, Caspase-2-deficient tumors are sensitive to chemotherapy and exhibit a significant reduction in tumor volume following repeated treatment. However, Caspase-2-deficient tumors rapidly rebound from chemotherapy with enhanced proliferation, ultimately hindering long-term therapeutic benefit. In response to DNA damage, Caspase-2 cleaves and inhibits Mdm2 and thereby promotes the stability of the tumor-suppressor p53. Caspase-2 expression levels are significantly reduced in human lung tumors with wild-type p53, in agreement with the model whereby Caspase-2 functions through Mdm2/p53 regulation. Consistently, p53 target genes including p21, cyclin G1 and Msh2 are reduced in Caspase-2-deficient tumors. Finally, we show that phosphorylation of p53-induced protein with a death domain 1 leads to Caspase-2-mediated cleavage of Mdm2, directly impacting p53 levels, activity and chemotherapy response. Together, these studies elucidate a Caspase-2-p53 signaling network that impacts lung tumorigenesis and chemotherapy response in vivo.
An Incremental-Charge-Based Digital Transmitter With Built-in Filtering (2015)

A fully integrated transmitter architecture operating in the charge-domain with incremental signaling is presented. The architecture provides improved out-of-band noise performance, thanks to an intrinsic low-pass noise filtering capability, reduced quantization noise scaled by capacitance ratios, and sinc 2 alias attenuation due to a quasi-linear reconstruction interpolation. With a respective unit and baseband capacitances of 2 fF and 45 pF, the architecture attains a potential 14 bit equivalent quantization noise with a 1024 unit capacitance array. Using four 10 bit charge-based DACs (QDACs) at 128 MS/s sampling rate, it achieves -155 dBc/Hz at 45 MHz offset from a 1 GHz modulated carrier. The incremental-charge-based operation also leads to an improved efficiency at back-off conditions. For an average output power of 1 dBm (20 MHz BW), total power consumption is 41.3 mW, of which only 0.5 mW corresponds to the system charge intake. The prototype is implemented using a 28 nm 0.9 V CMOS technology, with a core area of 0.25 mm 2 . With a reduced sampling frequency and number of bits, power and area consumption are among the best and will directly benefit from future technology scaling .
Kommentar der Schriftleitung (2016)

Liebe Leserinnen und Leser <b>Video-Editorial</b> <break/> <ext-link href="https://www.thieme.de/de/laryngo-rhino-otologie/profil-12497.htm ">www.thieme.de/lro</ext-link> <break/> <media href="10-1055-s-0042-106048-lro-05-16-v1.mp4" id="ME3-16-001" mediatype="video"/> <break/> <break/>
[Aneurysm of ascending aorta associated with aortic valve incompetence. Surgical correction by replacement of right coronary artery in 15 patients (author's transl)]. (1980)

15 patients with aneurysm of ascending aorta associated with aortic valve incompetence has been treated by the replacement of the aortic valve and ascending aorta with reimplantation of the right coronary artery in 8 patients and both coronary arteries in 7. The operative mortality was 13% (2 patients). The follow up interval ranged from 6 months to three years (mean 20 months) and in all 13 patients there was an improving of functional class. A post-operative angiography was performed in 6 patients and in all of them was demonstrated the patency of the neoostia, a minimum paravalvular leak in one patient, and a pseudoaneurysm in another one. Proving the necessity of complete replacement of aneurysmal aorta, the Authors discuss the technique adopted with particular reference to the problem of reimplantation of the coronary arteries.
Development of marine current turbines for electricity production (2011)

The recent and growing interest around the world in the utilisation of marine currents or tidal stream for the generating of electrical power, without the need for barrages and the impounding of water, is heralding a new era in renewable energy. Globally, marine currents are now being recognised as a resource to be exploited for the delivery of electrical power. The tides which drive such currents are highly predictable, being a consequence of the gravitational effects of the planetary motion of the earth, the moon and the sun. Although the energy in marine currents is generally diffuse, it is concentrated at a number of sites where sea flows are channelled through constraining topographies such as islands and straits. Harnessing such a resource can be achieved through utilising kinetic energy converters in a similar fashion as wind energy conversion. In addition the resource offers distinct advantages over other renewable energy sources due to its regular and predictable nature. The presented work discusses this potential and conveys the current status of marine current energy conversion. It also highlights research and development issues, reports on support mechanisms and technology development and deployment with special emphasis on the United Kingdom, currently the world leader in this field.
Design of a minimum temperature drift JFET differential amplifier (2003)

The temperature drift of a JFET (junction field-effect transistor) differential amplifier circuit is studied to determine the biasing conditions necessary to operate at zero temperature coefficient. Theoretical expressions for the currents and voltages at this point are determined. PSPICE results show close agreement with those obtained experimentally over a wide range of temperatures. Two methods for minimizing drift are investigated. A biasing method resulted in a drift of approximately 25 mu V/ degrees C over the range 25-50 degrees C. In the second method, using microprocessor control circuits, a drift of <10 mu V/ degrees C was obtained over the range of 25-85 degrees C.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
G<sub>1</sub>to S transition and pluripotency: Two sides of the same coin? (2009)

No abstract available.
Potassium Organotrifluoroborates in Rhodium‐Catalyzed Asymmetric 1,4‐Additions to Enones. (2003)

Abstract For Abstract see ChemInform Abstract in Full Text.
Pharmacokinetics of Vitamin K in Mothers and Children in the Perinatal Period: Transplacental Transport of Vitamin K<sub>2</sub> (MK‐4) (1991)

In order to examine the pharmacokinetics of vitamin K2, vitamin K2 (MK-4) was intravenously injected into mothers, and its transfer to placental tissue and the fetuses was examined. While incorporation of vitamin K2 into placental tissue was relatively active, transfer of vitamin K2 to fetal blood (cord blood) was small. So it was indicated that vitamin K2 incorporated into placental tissue from maternal blood is initially stored in the placenta and then gradually released into the fetal blood. Since vitamin K deficiency has been pointed out, release of vitamin K2 into milk was also examined. When vitamin K2 (MK-4) was injected into mothers, the release of vitamin K2 into milk increased with time even after the plasma vitamin K2 concentration in maternal blood decreased. So the presence of a vitamin K2 concentrating mechanism in the mammary tissue was indicated.
Processor Assignment and Synchronization in Parallel Simulation of (1989)

MULTISTAGE INTERCONNECTION NETWORKS (MIN''S), AN IMPORTANT CLASS OF NET- WORKS ARISING IN PARALLEL COMPUTER ARCHITECTURES, ARE EXCELLENT CANDIDATES FOR PARALLEL TIME-DRIVEN SIMULATION ON SHARED MEMORY COMPUTERS BECAUSE THEY ARE LARGE, INHERENTLY PARALLEL, REGULARLY STRUCTURED, DISCRETE TIME SYS- TEMS. IN THIS PAPER WE REPORT RESULTS FROM A CONTINUING STUDY ON THE PER- FORMANCE OF SUCH SIMULATIONS ON A SEQUENT SYMMETRY. OUR FOCUS IS THE CLASS OF BUFFERED DELTA NETWORKS CONSISTING OF 2 X 2 SWITCHES. WE REPORT RESULTS FOR SIMULATIONS OF MIN''S CONTAINING 4-9 STAGES AND REPORT ON THE EFFECTS THAT DIFFERENT SYNCHRONIZATION TECHNIQUES, DIFFERENT PROCESSOR TO SWITCH ALLOCATION STRATEGIES, AND NON-UNIFORM TRAFFIC PATTERNS IN THE WORKLOAD HAVE ON SIMULATION SPEEDUP. BRIEFLY, WE OBSERVE THAT A TWO-PHASE SYNCHRON- IZATION TECHNIQUE REQUIRING ONLY TWO BARRIERS DURING EACH CLOCK CYCLE PRO- VIDES THE BEST SPEEDUP. WE EXAMINE TWO PROCESSOR TO SWITCH ALLOCATION STRATEGIES, A `CONTIGUOUS'' ALLOCATION THAT ALLOCATES CONTIGUOUS ROWS OF SWITCHES TO EACH PROCESSOR, AND AN `INTERLEAVED'' ALLOCATION THAT ALLOCATES EVERY P-TH ROW TO EACH OF THE P PROCESSORS. WHILE THE CONTIGUOUS ALLOCA- TION EXHIBITS BETTER LOCALITY OF REFERENCE, FOR UNIFORM TRAFFIC THERE IS LITTLE DIFFERENCE IN PERFORMANCE BETWEEN THE TWO STRATEGIES. FOR NON-UNI- FORM TRAFFIC, WHEREAS THE SPEEDUP USING CONTIGUOUS ALLOCATION DEGRADES, THE SPEEDUP USING THE INTERLEAVED ALLOCATION REMAINS NEARLY CONSTANT. USING
Community multimedia cards: CoMu cards (2008)

Within the last years, the Web has developed into a content platform featuring rich multimedia content, dynamic establishments of communities and a continuously increasing importance of interaction and communication. This trend reveals new challenges when considering the increasing mobility of users
Crystallographic Orientation Relationships between Primary Silicon and Aluminum Halo Crystals in Al-Si Alloys Studied by the Micro-Focus X-ray Diffraction Analysis (1974)

Crystallographic orientation relationships between primary silicon and aluminum halo crystals in hyper-eutectic Al-Si alloys have been studied by micro-focus X-ray diffraction analysis.The apparently random orientation relationships have been classified into simple relationships when the twinnings in silicon crystals are taken into consideration. These relationships are;(This article is not displayable. Please see full text pdf.) \ oindentfor untreated alloys and,(This article is not displayable. Please see full text pdf.) \ oindentfor sodium treated alloys.The occurrence of relationships (1) for untreated alloys and (4) for sodium treated alloys are most frequent and it has been calculated that the relationships (2) and (3) are within 13.8° inclination from (1) and the relationships (5) and (6) are within 11.4° inclination from (4).The crystallographic relationships between silicon and aluminum for untreated and sodium treated alloys, when represented by (1) and (4) respectively, can be matched by a 54.7° rotation around the [001] axis of aluminum crystals.
Electrostatic catalysis. IV. Intramolecular carboxyl group electrostatic facilitation of the A-1-catalyzed hydrolysis of alkyl phenyl acetals of formaldehyde. Influence of oxocarbonium ion stability (1971)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTElectrostatic catalysis. IV. Intramolecular carboxyl group electrostatic facilitation of the A-1-catalyzed hydrolysis of alkyl phenyl acetals of formaldehyde. Influence of oxocarbonium ion stabilityBen M. Dunn and Thomas C. BruiceCite this: J. Am. Chem. Soc. 1971, 93, 22, 5725–5731Publication Date (Print):November 1, 1971Publication History Published online1 May 2002Published inissue 1 November 1971https://pubs.acs.org/doi/10.1021/ja00751a025https://doi.org/10.1021/ja00751a025research-articleACS PublicationsRequest reuse permissionsArticle Views186Altmetric-Citations24LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
An alternative bus clamp for resonant DC-link converters (1994)

This paper presents an alternative circuit configuration for clamping the link voltage in a resonant DC-link converter. The alternative circuit is a lossless clamp which allows for totally autonomous control of the clamp voltage and resonant link under all operating conditions. The clamp is comprised of two capacitors, three controllable switches and three diodes. The clamp does not require the use of external bias supplies for startup or no-load operation. Control of the input and/or output waveforms for a converter employing this circuit remains virtually identical to that for the resonant DC-link inverter (RDCLI). An analysis of clamp operation is performed detailing its modes of operation. From this analysis, insight is gained into the appropriate selection of clamp capacitors. Simulations and experimental results are presented to corroborate the analysis. The control of the clamp is discussed in detail.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Geological Structures of the Southern Jecheon, Korea: Uplift Process of Dangdusan Metamorphic Complex and Its Implication (2000)

Keumseong area in the southern part of the Jecheon city, the Ogcheon Belt, consists of Precambrian Dangdusan Metamorphic Complex, Dori Formation of the Choseon Supergroup, and Jurassic Jecheon Granite. The Dangdusan Metamorphic Complex consists of quartz schist, mica schist. quartzite and pegmatite. The Dori Formation is composed of mainly laminated limestone. The rocks in the study area have been undergone at least three phases of deformations since Paleozoic period. The Dangdusan Metamorphic Complex is outcrop at three areas in the study area, which are exposed along the faults and occurred as inlier within the Dori Formation. Previous authors interpreted the uplift of the Dangdusan Metamorphic Complex by the Dangdusan Fault, but we could not find any evidences related to the Dangdusan Fault. Thus, we interpret the uplift of the Dangdusan Metamorphic Complex due to the D Weolgulri and Dangdusan thrusts and post-D Jungbodeul, Kokyo and Jungjeonri faults. The uplift of the Busan Metamorphic Complex to the west of the study area was interpreted by ductile deformation. However, the Dangdusan Metamorphic Complex is formed by brittle thrusts and faults in this study. According to deformation sequence, the characters of deformations in the Choseon and Ogcheon suprergroups had been changed from ductile to brittle deformations through the time. Therefore, we interpret the Dangdusan Metamorphic Complex is exposed later than the Busan Metamorphic Complex.