gebhart/patrepeval huggingface dataset:
Bile acid transport into hepatocyte smooth endoplasmic reticulum vesicles is mediated by microsomal epoxide hydrolase, a membrane protein exhibiting two distinct topological orientations. (1993)

Abstract Bile acids, such as taurocholate, have been shown to be transported into hepatocyte smooth endoplasmic reticulum (SER) vesicles. This process is Na(+)-independent, electrogenic, inhibitable by 4,4'-diisothiocyanostilbene-2,2'-disulfonic acid and taurochenodeoxycholate, with a Km of 352 microM and a Vmax of 29.6 nmol/mg protein/min. The observed transport is mediated by the bifunctional protein, microsomal epoxide hydrolase (mEH) which can also mediate bile acid transport into hepatocytes across the sinusoidal plasma membrane (von Dippe, P., Amoui, M., Alves, C., and Levy, D. (1993) Am. J. Physiol. 264, G528-G534). mEH was isolated from SER membranes by immunoprecipitation with monoclonal antibody (mAb) 25D-1 which recognizes this protein on the surface of intact hepatocytes. The SER-derived protein exhibited an apparent molecular weight, isoelectric point, N-terminal amino acid sequence, and mEH-specific activity that were indistinguishable from the plasma membrane form of the enzyme. Proteoliposome reconstitution of the SER taurocholate transport system indicated that mEH was absolutely required for the expression of transport capacity. The interaction of mAb 25D-1 with mEH on intact right-side-out SER vesicles demonstrated that the epitope found on the surface of hepatocytes was also found on the cytoplasmic surface of these vesicles (80%) and in the lumen (20%) suggesting the presence of two forms of this protein in the SER, the latter from being sorted to the cell surface. The existence of two orientations of this protein in the SER was confirmed by the sensitivity to tryptic digestion, where 75% of the mAb epitope was accessible to the enzyme. The loss of the 25D-1 epitope correlated with loss of taurocholate transport capacity. The role of mEH in the transport process and the orientation of the transporting isoform was further established by demonstrating that mAb 25A-3, which also reacts with mEH on the hepatocyte surface, was able to directly inhibit taurocholate transport in the SER vesicle system. These and previous results thus establish that isoforms of mEH can mediate taurocholate transport at the sinusoidal plasma membrane and in SER vesicles and that this bifunctional protein can exist in two orientations in the SER membrane. The association of bile acids with the SER suggests a possible role of intracellular vesicles in the transhepatocellular movement of bile acids from the sinusoidal to the canalicular compartment.
Functional Recovery after Traumatic Transtentorial Herniation (1991)

Abstract To elucidate the factors associated with functional recovery after traumatic transtentorial herniation, we reviewed the records of 153 consecutive patients admitted with clinical signs of transtentorial herniation (altered level of consciousness, anisocoria or pupillary unresponsiveness, and abnormal motor findings). Overall, 28 patients (18%) had a functional outcome: 14 patients (9%) made a good recovery and 14 were moderately disabled. Sixteen patients (10.5%) were severely disabled or vegetative, and 104 (60%) died. Compared with patients who died or were left severely disabled or vegetative, patients who had a good recovery were younger (21 versus 38 years), were significantly more likely to be children (≤17 years old) and have anisocoria and a deteriorating Glasgow Coma Score (GCS), and were significantly less likely to be flaccid or have bilaterally fixed pupils; moderately disabled patients also had a lower median age and a higher frequency of anisocoria. There was no difference in the incidence of significant intracranial hematomas between patients with a functional outcome and those with a nonfunctional outcome. Twenty-seven percent of the 95 patients with anisocoria had a good outcome or moderate disability, whereas only 3.5% of the 58 patients with bilaterally fixed and dilated pupils at admission had a functional recovery (P &lt; 0.05). Age, level of consciousness, and the degree of residual upper brain stem function at admission appear to be the most important determinants of functional outcome after traumatic transtentorial herniation.
Integrating task and motion planning using semantic attachments (2010)

Solving real-world problems using symbolic planning often requires a simplified formulation of the original problem, since certain subproblems cannot be represented at all or only in a way leading to inefficiency. For example, manipulation planning may appear as a subproblem in a robotic planning context or a packing problem can be part of a logistics task. In this paper we propose an extension of PDDL for specifying semantic attachments. This allows the evaluation of grounded predicates, the change of fluents and the calculation of durations by externally specified functions. Furthermore, we describe a general schema of integrating semantic attachments into forward-chaining planning systems and report on our experience of adding this extension to the planner Temporal Fast Downward. Finally, we present some preliminary experiments using semantic attachments.
Combining Multiple Image Features to Guide Automatic Portrait Cropping for Rendering Different Aspect Ratios (2010)

Nowadays there exists a large variety of aspect ratios used for both image rendering (e.g. print media, TV, cinema screens etc.) and image acquisition devices (e.g. still and video cameras, scanners etc.). In order to maintain the image's original aspect ratio when adjusting for a different media, some level of cropping may be required, but the automatic zoom and crop method may not produce satisfactory results regarding image contents. This paper proposes an automatic method that analyses images and estimates the relevant content areas, avoiding distortions and main subject chopping. The analysis is performed by four feature extractors, each producing a grayscale image which indicates relevant image areas. The outputs of these extractors are then combined by means of a Genetic Algorithm (GA) optimization. Experiments involving a subjective evaluation of a set of automatically cropped images have shown that 77% of the 35 human observers considered images adjusted by the proposed approach better than or similar to the outputs of the automatic zoom and crop method.
Synthesis of Spiropyrrolidines and Spiropyrrolizidines by Azomethine Ylide Cycloaddition of Baylis-Hillman Adducts Derived from N-Methyl Maleimide (2010)

The stereoselective synthesis of a series of novel spiropyrrolidines and spiropyrrolizidines has been accomplished through an intermolecular 1,3-dipolar cycloaddition of an azomethine ylides with dipolarophiles derived from the Baylis-Hillman reaction of ­isatins with N-methyl maleimide.
Thermal analysis (1986)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThermal analysisW. W. WendlandtCite this: Anal. Chem. 1986, 58, 5, 1–6Publication Date (Print):April 1, 1986Publication History Published online1 May 2002Published inissue 1 April 1986https://pubs.acs.org/doi/10.1021/ac00296a001https://doi.org/10.1021/ac00296a001research-articleACS PublicationsRequest reuse permissionsArticle Views381Altmetric-Citations51LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Lo siniestro del enigma. (2010)

En "El nacimiento de la filosofía griega", Giorgio Colli nos muestra una faceta tenebrosa del enigma. El dios Apolo, de naturaleza ilimitada, insondable, caprichosa, plantea al hombre enigmas que lo enfrentan con el sufrimiento y con la muerte. Allí, Edipo se confronta con enigmas enviados por el dios en los que se pone en juego su propia existencia. Tiempo después, en el transcurrir del siglo XX, reaparece una nueva forma de este dios arbitrario y arrogante: el desaparecedor de personas, ese inmoderado que impone moderación, borra con su acto un cuerpo, una imagen, un nombre, y formula un nuevo enigma siniestro que enfrenta otra vez al hombre con el dolor y con la muerte.
The Role of Zinc in Selected Female Reproductive System Disorders (2020)

Zinc is an essential microelement that plays many important functions in the body. It is crucial for the regulation of cell growth, hormone release, immunological response and reproduction. This review focuses on its importance in the reproductive system of women of reproductive and postmenopausal ages, not including its well described role in pregnancy. Only recently, attention has been drawn to the potential role of zinc in polycystic ovary syndrome (PCOS), dysmenorrhea, or endometriosis. This review is mainly based on 36 randomized, controlled studies on reproductive, pre- and post-menopausal populations of women and on research trying to explain the potential impact of zinc and its supplementation in the etiology of selected female reproductive system disorders. In women with PCOS, zinc supplementation has a positive effect on many parameters, especially those related to insulin resistance and lipid balance. In primary dysmenorrhea, zinc supplementation before and during each menstrual cycle seems to be an important factor reducing the intensity of menstrual pain. On the other hand, little is known of the role of zinc in endometriosis and in postmenopausal women. Therefore, further studies explaining the potential impact of zinc and its supplementation on female reproductive system would be highly advisable and valuable.
Magnetic resonance imaging for radiotherapy planning of brain cancer patients using immobilization and surface coils (2009)

This study investigated the compatibility of a head and neck immobilization device with magnetic resonance imaging (MRI). The immobilization device is used to position a patient in the same way as when receiving a computed tomography (CT) scan for radiotherapy planning and radiation treatment. The advantage of using immobilization in MR is improved accuracy in CT/MR image registration enabling greater confidence in the delineation of structures. The main practical difficulty in using an immobilization device in MRI is that physical constraints make their use incompatible with head imaging coils. Within this paper we describe a method for MR imaging of the brain which allows the use of head and neck immobilization devices. By a series of image quality tests we obtained the same or better image quality as a multi-channel head coil.
SIMULTANE ONLINE-ANALYSE VON ABGASEN MIT EINEM LASER-RAMAN-POLYCHROMATOR (1996)

Aufgrund der steigenden Anforderungen an Abgasanalysesysteme insbesondere fuer die Entwicklung schadstoffarmer Motoren und die Entwicklung von Katalysatoren wurde am Institut fuer Spektrochemie und angewandte Spektroskopie in Dortmund ein Raman-Polychromator entwickelt und aufgebaut. Das Messsystem bietet die Moeglichkeit zur simultanen quantitativen online Analyse und wurde sowohl an stationaeren Abgasproben als auch online bei sich aendernden Motorbedingungen erprobt. Wesentliche Vorteile im Vergleich zu kommerziellen Abgasanalysatoren sowie auch gegenueber neueren Entwicklungen von FTIR-Abgasanalysesystemen zeigt der Raman-Spetrometer dadurch, dass keine speziellen Eichgase benoetigt werden, dass zusaetzlich die Abgaskomponenten O2, H2 und N2 registriert werden, sowie durch die Ausnutzung von Resonanzeffekten mit geeigneten Lasern zum Beispiel polyzyklische aromatische Kohlenwasserstoffe in sehr geringen Konzentrationen nachgewiesen werden koennen. Text in Englisch: Simultaneous online analysis of exhaust gases with a laser raman polychromator.
Sphingolipids, Insulin Resistance, and Metabolic Disease: New Insights from in Vivo Manipulation of Sphingolipid Metabolism (2008)

Obesity and dyslipidemia are risk factors for metabolic disorders including diabetes and cardiovascular disease. Sphingolipids such as ceramide and glucosylceramides, while being a relatively minor component of the lipid milieu in most tissues, may be among the most pathogenic lipids in the onset of the sequelae associated with excess adiposity. Circulating factors associated with obesity (e.g., saturated fatty acids, inflammatory cytokines) selectively induce enzymes that promote sphingolipid synthesis, and lipidomic profiling reveals relationships between tissue sphingolipid levels and certain metabolic diseases. Moreover, studies in cultured cells and isolated tissues implicate sphingolipids in certain cellular events associated with diabetes and cardiovascular disease, including insulin resistance, pancreatic beta-cell failure, cardiomyopathy, and vascular dysfunction. However, definitive evidence that sphingolipids contribute to insulin resistance, diabetes, and atherosclerosis has come only recently, as researchers have found that pharmacological inhibition or genetic ablation of enzymes controlling sphingolipid synthesis in rodents ameliorates each of these conditions. Herein we will review the role of ceramide and other sphingolipid metabolites in insulin resistance, beta-cell failure, cardiomyopathy, and vascular dysfunction, focusing on these in vivo studies that identify enzymes controlling sphingolipid metabolism as therapeutic targets for combating metabolic disease.
Optically transparent balloon antenna (2015)

Based on Indium tin oxide (ITO) films and a cylindrical polyvinyl chloride (PVC) balloon, an optically transparent conformal log-periodic balloon antenna is presented in this paper. This antenna includes six cylindrically-conformal bowtie elements and is cross-fed by a parallel-strip transmission line. A comparative analysis is carried out for the proposed design using different types of commercial ITO films and perfect electric conductor (PEC) taper, respectively. Measured results of a fabricated prototype are in good agreement with simulated ones, which demonstrates the good radiation performance of the balloon antenna over a wide frequency band from 200 MHz to 500 MHz.
Pneumocystis carinii (2002)

Pneumocystis carinii is an atypical fungus that causes pneumonia in immunocompromised individuals. P. carinii comprises a heterogeneous group of organisms that have been isolated from a wide range of mammalian host species. P. carinii infection is host species specific, the P. carinii organisms that infect humans have only been found in humans. This review discusses the application of molecular techniques to the study of the biology and epidemiology of P. carinii infection. It addresses the use of DNA amplification for the detection and diagnosis of P. carinii pneumonia. Studies investigating the reservoir of infectious P. carinii organisms, the routes of transmission of the infection, and the emergence of drug resistant strains of P. carinii are also discussed.
Naming faces in broadcast news video by image google (2008)

Naming faces is important for news videos browsing and indexing. Although some research efforts have been contributed to it, they only use the concurrent information between the face and name or employ some clues as features and use simple heuristic method or machine learning approach to finish the task. They use little extra knowledge about the names and faces. Different from previous work, in this paper we present a novel approach to name the faces by exploring extra knowledge obtained from image google. The behind assumption is that the faces of those important persons will turn out many times in the web images and could be retrieved from image google easily. Firstly, faces are detected in the video frames; and the name entities of candidate persons are extracted from the textual information by automatic speech recognition and close caption detection. Then, these candidate person names are used as queries to find the name related person images through image google. After that, the retrieved result is analyzed and some typical faces are selected through feature density estimation. Finally, the detected faces in the news video are matched with the faces selected from the result returned by image google to label each face. Experimental results on MSNBC news and CNN news demonstrate that the proposed approach is effective.
Weather Based Strawberry Yield Forecasts at Field Scale Using Statistical and Machine Learning Models (2019)

Strawberry is a high value and labor-intensive specialty crop in California. The three major fruit production areas on the Central Coast complement each other in producing fruits almost throughout the year. Forecasting strawberry yield with some lead time can help growers plan for required and often limited human resources and aid in making strategic business decisions. The objectives of this paper were to investigate the correlation among various weather parameters related with strawberry yield at the field level and to evaluate yield forecasts using the predictive principal component regression (PPCR) and two machine-learning techniques: (a) a single layer neural network (NN) and (b) generic random forest (RF). The meteorological parameters were a combination of the sensor data measured in the strawberry field, meteorological data obtained from the nearest weather station, and calculated agroclimatic indices such as chill hours. The correlation analysis showed that all of the parameters were significantly correlated with strawberry yield and provided the potential to develop weekly yield forecast models. In general, the machine learning technique showed better skills in predicting strawberry yields when compared to the principal component regression. More specifically, the NN provided the most skills in forecasting strawberry yield. While observations of one growing season are capable of forecasting crop yield with reasonable skills, more efforts are needed to validate this approach in various fields in the region.
Stratified planning (2009)

Most planning problems have strong structures. They can be decomposed into subdomains with causal dependencies. The idea of exploiting the domain decomposition has motivated previous work such as hierarchical planning and factored planing. However, these algorithms require extensive backtracking and lead to few efficient general-purpose planners. On the other hand, heuristic search has been a successful approach to automated planning. The domain decomposition of planning problems, unfortunately, is not directly and fully exploited by heuristic search. We propose a novel and general framework to exploit domain decomposition. Based on a structure analysis on the SAS+ planning formalism, we stratify the sub-domains of a planning problem into dependency layers. By recognizing the stratification of a planning structure, we propose a space reduction method that expands only a subset of executable actions at each state. This reduction method can be combined with state-space search, allowing us to simultaneously employ the strength of domain decomposition and high-quality heuristics. We prove that the reduction preserves completeness and optimality of search and experimentally verify its effectiveness in space reduction. 1
Does resin based dentine bonding work? (1995)

Since Buonocore, in the mid 1950s, introduced enamel etching to be used to bond resinous restorations to enamel, different resin based bonding procedures have continuously found their way into dental practise. Today, dentists bond materials not only to enamel, but also to dentine. Up until recently, the clinical success with dentine bonding agents had been unreliable at best, and many clinicians had become sceptical as to whether it would ever be possible to bond to dentine. In this paper, some of the important break-throughs in the field of dentinal adhesives are reviewed in an attempt to throw some light on the question, does resin based dentine bonding work? The technical procedure used to optimise dentine bonding is reviewed, emphasising the significance of etching dentine, placing the primer on a slightly moist dentine surface, avoiding oxygen inhibition of the bonding resin, and maximising the degree of cure. In addition, emphasis is also placed on the significance of variations in dentine structure, and how sclerotic dentine may make dentine bonding less efficient. The conclusion of the entire review is that although significant improvements have been made in the field of dentine bonding during the last few years, it is still too early to conclude that dentine bonding will survive several years of clinical service.
ParC++: a simple extension of C++ to parallel systems (2002)

The ParC++ system is an object oriented programming and execution environment, based on a programming model that aims the development of portable, efficient and scalable parallel applications. The paper presents the main components in the ParC++ system: a pre-processor-that supports a parallel extension to C++ objects and extracts parallelism from standard C++ code-and a run-time system-that dynamically adapts the grain size of parallel activities, according to the computing and communication system load.
Nitrogen-doped Porous Carbon Derived from Rapeseed residues for High-performance Supercapacitors (2016)

In this paper, nitrogen-doped activated carbons obtained from rapeseed residues (N-RCs) as supercapacitor electrodes are successfully synthesized by a simple chemical activation method. The field emission scanning microscope, transmission electron microscopy, and N2 adsorption-desorption tests demonstrate that N-RCs treated with ZnCl2 can produce a large number of mesopores. Additionally, the N-RCs have certain amount of nitrogen (nitrogen content in N-RC2 is 6.55% by element content analysis). As the electrode material, N-RC2 exhibits ideal capacitive behavior in 6 mol L-1 KOH aqueous electrolyte in a three-electrode system tests, and the maximum specific capacitance reaches 250 F g-1 at a current density of 0.5 A g-1. Furthermore, in 0.5 mol L-1 Na2SO4 aqueous electrolyte, the as-assembled N-RC2//N-RC2 symmetric cell exhibits high energy density of 13.55 Wh kg-1 at a power density of 399.80 W kg-1 operated at the voltage range of 0 to 1.8 V and an excellent cycleability retaining about 92.8% initial capacitance after 5000 cycles.
High-precision high-sensitivity clock recovery circuit for a mobile payment application (2011)

This paper presents a fully integrated carrier clock recovery circuit for a mobile payment application. The architecture is based on a sampling-detection module and a charge pump phase locked loop. Compared with clock recovery in conventional 13.56 MHz transponders, this circuit can recover a high-precision consecutive carrier clock from the on/off keying (OOK) signal sent by interrogators. Fabricated by a SMIC 0.18-μm EEPROM CMOS process, this chip works from a single power supply as low as 1.5 V Measurement results show that this circuit provides 0.34% frequency deviation and 8 mV sensitivity.