gebhart/patrepeval huggingface dataset:
Acute phase reaction and acute phase proteins (2005)

A review of the systemic acute phase reaction with major cytokines involved, and the hepatic metabolic changes, negative and positive acute phase proteins (APPs) with function and associated pathology is given. It appears that APPs represent appropriate analytes for assessment of animal health. Whereas they represent non-specific markers as biological effect reactants, they can be used for assessing nutritional deficits and reactive processes, especially when positive and negative acute phase variables are combined in an index. When such acute phase index is applied to separate healthy animals from animals with some disease, much better results are obtained than with single analytes and statistically acceptable results for culling individual animals may be reached. Unfortunately at present no cheap, comprehensive and easy to use system is available for assessing various acute phase proteins in serum or blood samples at the same time. Protein microarray or fluid phase microchip technology may satisfy this need; and permit simultaneous analysis of numerous analytes in the same small volume sample and enable integration of information derived from systemic reactivity and nutrition with disease specific variables. Applying such technology may help to solve health problems in various countries not only in animal husbandry but also in human populations.
Hanzi, Concept and Computation: A Preliminary Survey of Chinese Characters as a Knowledge Resource in NLP (2006)

There are many people to whom I owe a debt of thanks for their support, for the completion of my thesis and supported me in science as well in privacy during this time. First, I would like to sincerely thank my advisor, Prof. Dr Erhard Hin-richs, under whose influence the work here was initiated during my fruit-ful stay in Germany. Without his continuous and invaluable support, this work could not have been completed. I would also like to thank Prof. Dr. Eschbach-Szabo for reading this thesis and offering constructive comments. Besides my advisors, I am deeply grateful to the rest of my thesis commit-tee: Frank Richter and Fritz Hamm, for their kindly support and interesting questions. A special thanks goes to Lothar Lemnitzer, who proofread the thesis carefully and gave insightful comments. I would like to thank my parents for their life-long love and support. Last but not least, I also owe a lot of thanks to my lovely wife Hsiao-Wen, my
Rate-Decline Analysis for Fracture-Dominated Shale Reservoirs (2011)

Summary Traditional decline methods such as Arps’ rate/time relations and their variations do not work for wells producing from supertight or shale reservoirs in which fracture flow is dominant. Most of the production data from these wells exhibit fracture-dominated flow regimes and rarely reach late-time flow regimes, even over several years of production. Without the presence of pseudoradial and boundary-dominated flows (BDFs), neither matrix permeability nor drainage area can be established. This indicates that matrix contribution is negligible compared with fracture contribution, and the expected ultimate recovery (EUR) cannot be based on a traditional concept of drainage area. An alternative approach is proposed to estimate EUR from wells in which fracture flow is dominant and matrix contribution is negligible. To support these fracture flows, the connected fracture density of the fractured area must increase over time. This increase is possible because of local stress changes under fracture depletion. Pressure depletion within fracture networks would reactivate the existing faults or fractures, which may breach the hydraulic integrity of the shale that seals these features. If these faults or fractures are reactivated, their permeabilities will increase, facilitating enhanced fluid migration. For fracture flows at a constant flowing bottomhole pressure, a log-log plot of rate over cumulative production vs. time will yield a straight line with a unity slope regardless of fracture types. In practice, a slope of greater than unity is normally observed because of actual field operations, data approximation, and flow-regime changes. A rate/ time or cumulative production/time relationship can be established on the basis of the intercept and slope values of this log-log plot and initial gas rate. Field examples from several supertight and shale gas plays for both dry and high-liquid gas production, and for oil production were used to test the new model. All display the predicted straightline trend, with its slope and intercept related to reservoir types. In other words, a certain fractured flow regime or a combination of flow types that dominate a given area or play because of its reservoir-rock characteristics and/or fracture-stimulation practices all produce a narrow range of intercepts and slopes. An individualwell performance or EUR can be derived that is based on this range if the best 3-month average or the initial production rate of the well is already known or estimated. The results show that this alternative approach is easier to use, gives a reliable EUR, and can be used to replace the traditional decline methods for unconventional reservoirs. The new approach is also able to provide statistical methods to analyze production forecasts of resource plays and to establish a range of results of these forecasts, including probability distributions of reserves in terms of P90 (lower side) to P10 (higher side).
Based on three-dimensional geological modeling of geological section (2011)

With the development of computer technology and geological modeling study of the gradual maturity, 3D for the engineering geological modeling and information visualization analysis system of opportunities and challenges brought about. Have carried on the detailed introduction to the three dimensional geological modeling tool and the method. Summarized the three dimensional geological modeling basic step. Surface topography information deduce the initial construction of the geological model project. Carry out the calculation of occurrence. How to use the discrete value of the occurrence of information, production level surface equation method , And study of the surface intersection, Initial generation of 3D geological model .This paper discusses the adoption of the new access to the geological information on how to modify the initial model editor .Application algorithm for the generation of surface fitting interpolation. Display system for the section of geological strata, faultage and three-dimensional geological model of the effect drawings of block geological. At the same time, it provides a reliable scientific authority for the decision-making of the underground construction projects.
Prime DC/AC Buck-Boost Converter (2012)

Introducing a transmission line into the fundamental power conversion circuits (Buck, Boost and Buck-Boost) has given the possibility to create converters types with new properties.A modified Buck-Boost converter in DC/AC operation has been evaluated.The main goal was to verify if a DC/AC conversion could be made and to optimize its efficiency with different lumped transmission lines (LTL).The idea was to decrease the total area of the LTL in order to make the solution more attractive for the power electronic market.Moreover, there was no theoretical explanation of the converter.Therefore the transfer function was investigated and a mathematical explanation of the converter was provided.The converter works in two different modes, inverting and non-inverting.In its inverting mode it works as a regular Buck-Boost converter and in its non-inverting mode it can provide an output voltage with the same polarity as the input voltage.The current and voltage wave propagating inside the LTL can be described with general microwave theory.The converter was also proven to work in DC/AC mode and has an efficiency of 69% with a LTL with U-core inductors.The efficiency can be interpreted as low since old measurements with an LTL incorporating surface mounted inductors instead, showed an efficiency of 81%.The decrease in efficiency is most likely due to a malfunctioning MOSFET.In non-inverting mode the efficiency was increased with two of the U-core LTLs.The Prime Buck-Boost solution has great potential, but at the moment the efficiency is too low and the total area is too big.An investigation of the converter in AC/DC mode with GaN switches and LTLs with E-cores has been proposed for future work.
The Sartrean Self: Ambivalent or Paradoxical (1983)

SUNY Brockport
Capsaicin attenuates suppression of sham feeding induced by intestinal nutrients (1988)

Satiety appears to be mediated in part by neurally transmitted signals from the gastrointestinal tract. Capsaicin is a neurotoxin that selectively destroys small unmyelinated primary sensory neurons including some of those innervating the abdominal viscera. Therefore, we examined suppression of sham feeding induced by cholecystokinin octapeptide (CCK-8) or intraintestinal nutrient infusions in capsaicin-treated rats. Suppression of sham feeding induced by CCK-8 was significantly attenuated in rats treated with capsaicin. Suppression of sham feeding induced by intraintestinal infusions of maltose, oleic acid, or L-phenylalanine was also attenuated in capsaicin-treated rats. In contrast, capsaicin treatment did not attenuate the suppression of sham feeding induced by intraintestinal casein hydrolysate (mixed amino acids). Intraintestinal infusions of octanoic acid or D-phenylalanine solutions did not significantly suppress sham feeding in either vehicle- or capsaicin-treated rats. These results indicate that the suppression of feeding by some intestinal stimuli may be mediated by nutrient or peptide-sensitive visceral afferent neurons that are sensitive to damage or destruction by capsaicin.
Strassburger Aufenthalt und Rückkehr nach Mainz (1978)

Da Gutenberg die Rückkehr nach Mainz abgelehnt hatte und die Stadt Mainz ihm daraufhin die Auszahlung der Leibrente sperrte, führte er mit seiner Vaterstadt einen Rechtsstreit um die Renten und Zinsen, deren Summe im Jahr 1434 immerhin 310 rheinische Gulden betrug.
Warm ischemia-reperfusion injury is decreased by tacrolimus in steatotic rat liver (2006)

Ischemia-reperfusion (I-R) injury is poorly tolerated by fatty livers, most probably secondary to reduced cellular adenosine triphosphate (ATP) levels. We investigated the effectiveness of tacrolimus pretreatment on fatty liver I-R injury in obese Zucker rats. Tacrolimus (0.3 mg/kg, intravenously) was injected 24 hours before a 75-minute ischemic period and rats were sacrificed 6 hours later. Tacrolimus modified the response to I-R observed in obese Zucker rats, when compared to nontreated obese rats: a significant reduction in hepatocyte necrosis was associated with a significant increase in hepatocyte apoptosis. In addition, cell necrosis and apoptosis were significantly and inversely correlated in lean nontreated and treated obese Zucker rats following I-R. Tacrolimus also significantly increased the hepatic ATP levels, reduced in nontreated obese rats, toward values found in lean Zucker rat livers. This protective effect of tacrolimus was further confirmed in vivo by a significantly improved survival following pretreatment with tacrolimus, 24 hours prior to ischemia. In conclusion, in obese Zucker rat livers, tacrolimus pretreatment reversed the I-R injury toward the one found in lean Zucker rats. The correlations between ATP levels and the opposite changes in necrosis and apoptotic pathways strongly suggest a cause-effect relationship between tacrolimus and changes in ATP levels.
Multimedia: Making It Work (1993)

From the Publisher:
No longer in the realm of smoke and mirrors, multimedia has finally established itself as the premier technology for creating everything from dynamic business presentations to virtual worlds of sight, sound, and motion. Making multimedia can be simple if you know where to start. Tay Vaughan, multimedia pioneer and expert, will guide you through the mysteries of multimedia - from conception to ultimate project delivery. With prose as colorful as the world of multimedia, Vaughan starts with hardware and software basics - what you need to get started and to be prepared for the future. He moves on to discuss core building blocks of multimedia: graphics, animation, audio, video, and text. Once you're clear on the concepts, you'll be ready to develop your own multimedia projects. In this newly revised edition of Multimedia: Making It Work discover the practical elements of making multimedia, such as cost, content gathering, and client considerations; learn how to differentiate and select the right text, sound, graphic, and video elements for your unique projects; perfect your ideas by following sample project plans and learning from real-world examples; understand the latest technology developments and how they affect you; and get the necessary multimedia background and theory with practical examples and real-world stories so you can make the right choices. As a special bonus, Multimedia: Making It Work includes a CD-ROM from Macromedia, the leading maker of multimedia development tools for both Mac and Windows. Offering limited working versions of all Macromedia products, this Product Showcase CD-ROM will allow you to test out your new skills and ideas risk-free! If you are an experienced multimedia maker or new to multimedia and want to find out what it's all about, Multimedia: Making It Work, Second Edition, is the ultimate resource about the real world of multimedia. This book is ideal for putting the power and impact of multimedia to work for you.
Association between the Gensini Score and Carotid Artery Stenosis (2016)

The Gensini score may be used to identify patients at high risk for significant carotid stenosis prior to CABG.
muMQ: A lightweight and scalable MQTT broker (2017)

A message broker is an imperative component in IoT systems, and it works as a gateway between IoT devices and application platforms. With the growth of IoT devices today, these systems can easily overwhelm message brokers unless the software can fully utilize hardware resources such as multi-core facility. This paper presents muMQ, a high-performance MQTT broker running on Commercial-Off-The-Shelf hardware. It tackles the challenge to improve the performance of message brokering on a single machine by efficiently utilizing multi-core CPUs. First, muMQ exploits an event-driven I/O mechanism for multi-core scalability. Each CPU core equally handles dispatched TCP connections and locally processes MQTT logic. Second, muMQ adopts a user-level TCP/IP stack, mTCP with DPDK, to avoid the overhead of the in-kernel TCP/IP stack, including system call overhead and resource contention. We evaluate the effectiveness of our approach through experiments. The results show that muMQ can handle 512K or greater long-lived subscribers with no message loss; muMQ achieves a publish messaging rate at 930K messages per second, which is 5.38 times faster than an existing MQTT broker. We also confirm mTCP accelerates the performance by 1.8 times compared with muMQ using the in-kernel TCP/IP stack.
Optimal codomains for the Laplace operator and the product Laplace operator (2007)

An optimal codomain for an operator P ( ∂ ) with fundamental solution E , is a maximal space of distributions T for which it is possible to define the convolution E * T and thus to solve the equation P ( ∂ ) S = T . We identify optimal codomains for the Laplace operator in the Euclidean case and for the product Laplace operator in the product domain case. The convolution is understood in the sense of the S ′ ‐convolution.
SOURCES OF CELLULOSE AND THEIR APPLICATIONS - A REVIEW (2011)

cellulose is a polysaccharide polymers.The amalgamation of polymer and pharmaceutical sciences led to the introduction of polymer in the design and development of drug delivery systems. Polymeric delivery systems are mainly intended to achieve controlled or sustained drug delivery. The major industrial source of cellulose is vascular plants. Resources for most applications in the building industry, and the cotton plant are the major source for textiles. Most paper products originate from wood pulp, while textile fibers are generally not isolated from woody fibers. Cotton fibers are a biological source of almost pure cellulose, but this is not usually used in food grade cellulose and are used instead for various cellulose derivatives, pharmaceutical, or chemical engineering uses, such as chromatography, paints, and explosives. Some other sources for cellulose are jute, hemp, corn, flasks, rice, wheat straw, sisal. Bacterial sources of cellulose have also been developed using Acetobacter xylinum that ferment substrates of glucose from corn syrup Different sources of cellulose are used for different purposes, for economic reasons. Pulp and paper are usually produced from wood Different extraction procedures for cellulose have been developed, By using different processes oxidation, micronization, etherification and esterification convert the prepared celluloses in to cellulose derivatives. The obtained derivatives are hydroxylpropylmethylcellulose(HPMC),
Smart data synchronization in m-Health monitoring applications (2014)

Nowadays, mobile applications/devices have become the trends, especially, when they were gradually shifted from basic communication services to supporting more sophisticated service provisioning. Mobile applications are usually very light, are nowadays likely to be often connected to the Internet, and can be used quite easily. However, these applications exhibit some challenges related to limited resources they have access to, including limited processing power, memory, storage size, battery power, and intermittent network connection. In fact, these considerations have to be taken seriously into consideration when developing mobile applications especially if those applications will be used for critical services, for example, to collect and report vital health data over a long period of time. In this paper, we study the use of mobile applications for monitoring patient's vital. Mobile devices, through an application, are connected to body-strapped biosensors to collect and synchronize these parameters with information systems. This synchronization should be done in such a way that the cost of synchronization is kept low and urgent readings are delivered as soon as possible. To optimize the synchronization process and reduce its cost, we propose and validate cost-oriented algorithms. A case study is developed to illustrate the applicability and effectiveness of our innovative techniques in making continuous monitoring an efficient process.
Hepatic Injury in the Toxic Epidemic Syndrome Caused by Ingestion of Adulterated Cooking Oil (Spain, 1981) (1984)

We describe the clinico-pathological characteristics of hepatic injury associated with the toxic-epidemic syndrome caused by the consumption of adulterated rapeseed oil. Of 842 toxic-epidemic syndrome patients admitted to our hospital between May, 1981, and January, 1982, 24.1% showed signs of liver involvement which was more frequent in women and in the fourth decade of life. No statistical significance was found in relation to alcohol consumption, treatment with potentially hepatotoxic antibiotics, or adult respiratory distress syndrome. Most (91.6%) patients with hepatic injury were asymptomatic; jaundice or abdominal pain was rarely noted. One patient died of acute liver failure following Budd-Chiari syndrome. Serum gamma-glutamyl transpeptidase activity was raised in all cases, alkaline phosphatase in 94.6%, and less frequently lactate dehydrogenase (80%), SGPT (84.7%), and SGOT (76%). Serum total bilirubin was usually normal (89.2%). The histologic lesion was similar to drug-induced cholestatic hepatitis. Lamellar inclusions, canalicular injury, giant mitochondria, and hyperplasia of the smooth endoplasmic reticulum were seen by electron microscopy. Ultrastructural signs of cholestasis were common (78.9%). The pathogenesis of this lesion is unknown; however, because of similarities with chlorpromazine-induced cholestatic hepatitis, we suggest that a combination of hypersensitivity and intrinsic hepatoxicity is a possible mechanism.
Simulation of Regional Freight Movement with Trade and Transportation Multinetworks (2003)

A simulation model called Trade and Transportation Multinetworks (TTMNet), constructed for the purpose of studying the effects of highly developed information technologies and logistic strategies (e.g., electronic commerce and real-time information) on freight transportation, is described. TTMNet is formulated as a multilevel product supply chain system that integrates the financial, informational, logistical, and physical aspects of transportation networks and allows interactions between each of these networks. Several simulators, including a freight traffic simulator, a supply chain decision-making simulator, and a pseudo-real-time information simulator, are involved. The freight traffic simulation is the focus of the present study. As part of this simulator, a learning model is set up to help decision makers estimate transportation costs on the basis of past experiences. Given the stochastic nature of these transportation costs and of the freight demands simulated by the system, the route for an origin–destination shipment may not remain optimal during a trip and may change along the way. A vehicle redirection procedure that handles this is presented. A numerical example is designed to compare a set of freight movements under two scenarios, one supported by and the other not supported by pseudo-real-time information on traffic conditions.
Basic impregnation techniques [for windings] (2002)

This paper discusses some of the reasons for the impregnation of electrical devices, and how they can help determine the best material and technique. Additionally, it defines each technique, and lists the pros and cons of each, for each application.
Discovery of Hydrocarbon-Stapled Short α-Helical Peptides as Promising Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Fusion Inhibitors (2018)

The hexameric α-helical coiled-coil formed between the C-terminal and N-terminal heptad repeat (CHR and NHR) regions of class I viral fusion proteins plays an important role in mediating the fusion of the viral and cellular membranes and provides a clear starting point for molecular mimicry that drives viral fusion inhibitor design. Unfortunately, such peptide mimicry of the short α-helical region in the CHR of Middle East respiratory syndrome coronavirus (MERS-CoV) spike protein has been thwarted by the loss of the peptide's native α-helical conformation when taken out of the parent protein structure. Here, we describe that appropriate all-hydrocarbon stapling of the short helical portion-based peptide to reinforce its bioactive secondary structure remarkably improves antiviral potency. The resultant stapled peptide P21S10 could effectively inhibit infection by MERS-CoV pseudovirus and its spike protein-mediated cell-cell fusion; additionally, P21S10 exhibits improved pharmacokinetic properties than HR2P-M2, suggesting strong potential for development as an anti-MERS-CoV therapeutic.
Compact in-line interferometer for low-coherence reflectometry (1995)

An interferometer with an efficient confocal layout is described. Similar in structure to a folded Linnik microscope, the interferometer employs broadband illumination to improve rejection of out-of-focus light. A prototype reflectometry system based on the new interferometer achieved an axial resolution of less than 10 μm within a probing depth of 1 mm in samples containing particulate scatterers and specularly reflecting objects. Options for mechanical and electronic scanning are discussed.