gebhart/patrepeval huggingface dataset:
Conformation Changes of Proteins (1954)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTConformation Changes of ProteinsRufus Lumry and Henry EyringCite this: J. Phys. Chem. 1954, 58, 2, 110–120Publication Date (Print):February 1, 1954Publication History Published online1 May 2002Published inissue 1 February 1954https://pubs.acs.org/doi/10.1021/j150512a005https://doi.org/10.1021/j150512a005research-articleACS PublicationsRequest reuse permissionsArticle Views2715Altmetric-Citations735LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
The influence of sex and maturity stage of krill (Euphanusia superba Dana) upon the content and composition of its lipids (1991)

Using a thin layer chromatography the content and composition of krill lipids was examined in different sex and maturity stages. The content of lipids decreased in the following sequence: immature males — females with eggs — juvenile specimens — spent females — mature males. In females the differences concerned mainly phospholipids and waxes, in males — triacylglicerols; this fact proves the different utilisation of lipids for reproduction in both sexes. K e y w o r d s : Antarctica, krill, lipids.
Normal Coordinate Analysis of “Footballene” C<sub>60</sub> (1988)

Abstract An approximate force field previously developed for condensed aromatics is adapted to footballene, a C60 molecule of icosahedral symmetry. The 46 vibrational frequencies are calculated. For a general introduction to the interesting (hypothetical) C60 molecule called “footballene” it is referred to another paper in this issue [3], In the present work the reported symmetry coordinates [3] are used to calculate the assigned vibrational frequencies of footballene.
Drop-Weight Tear Test—Effect of Variables on Test Results (1970)

Variables studied in this evaluation of the Battelle type drop-weight tear test (DWTT) include operator, test machine, specimen thickness, notch type, and strength level of the material tested. Operator and machine variations were found to be small. For a given material, increasing the specimen thickness raises the plateau energy and the transition temperature. Energy at a given percent shear is proportional to thickness. Notches examined include pressed notch, machined notch, fatigue crack, and crack starter weld. Continued use of the pressed notch is recommended. A side grooved DWTT specimen is used to compare the toughness of heat affected zones of welded specimens to that of the base metal. Work in this area is continuing.
Fixing a Broken System: Reconciling State Foreclosure Law with Economic Realities (2024)

58 Bankers across the country are concerned about changes in foreclosure law, because
A new triggering technology based on inductive transformer for LTD switches (2012)

The Linear Transformer Driver (LTD) technology is a new approach to construct high-voltage, high-current pulsed-power accelerators. Linear Transformer drivers, however, place stringent demands on synchronous trigger system. The paper proposes a new synchronous triggering technology, which is named as LTD-trigger. The LTDtrigger divides a pulse to a number of synchronous pulses through inductive transformer. Hence, the LTD-trigger is a kind of induction voltage divider and it operates like a reversed-LTD. The configuration of LTD-trigger is similar to LTD and the output port and input port is opposite to LTD. In order to analyze the working principle of LTDtrigger, an equivalent circuit model and an experimental prototype are established. The LTD-trigger experimental prototype can generate 20 synchronous trigger pulses with voltage amplitude of 23 kV and rise time of about 70 ns. The simulation and experimental results show a good performance of synchronization among the output trigger pulses. The stability of LTD-trigger is tested while some circuit faults occur.
Owen Willans Richardson, 1879-1959 (1960)

Abstract Owen Willans Richardson, one of the most outstanding men of science of this century, was born on 26 April 1879 at Dewsbury, Yorkshire; the son of Josiah H. Richardson and Charlotte M. Richardson. Most of his early childhood was spent at the little mining village of Askern near Doncaster and both his parents are buried there. He was a very precocious boy and gained so many scholarships and exhibitions that his education cost his parents nothing at all. He was a pupil at Batley Grammar School till about 1897 and there is an entry at the school, in the Register kept for the ‘Department of Science and Art’, which, as many older men will remember, used to hold examinations all over England: ‘O. W. Richardson, age last birthday 13, date of entering school September ’91. Address Victoria Crescent, Dewsbury. Father’s occupation: Traveller. Signed O. Richardson.’ According to the present Headmaster, Mr F. W. Scott, Batley Grammar School was founded in 1612 and built beside the Parish Church, but moved up the hill in 1878 to new buildings. It has produced many learned men and scientists; but like many other schools (or indeed most schools) it suffered severely from the tyranny of examinations, that bane of education in England.
The Netherlands Mental Health Survey and Incidence Study‐2 (NEMESIS‐2): design and methods (2010)

The psychiatric epidemiological population study NEMESIS-2 (Netherlands Mental Health Survey and Incidence Study-2) replicates and expands the first Netherlands Mental Health Survey and Incidence Study (NEMESIS-1) conducted from 1996 to 1999. The main objectives of the new study are to provide up-to-date figures on the prevalence, incidence, course and consequences of mental disorders, and to study trends in mental disorders and service use, with the use of a new sample. New topics not included in NEMESIS-1 were added, e.g. impulse-control disorders, and genetic correlates of mental disorders through gathering DNA from saliva samples. This paper gives an overview of the design of NEMESIS-2, especially of its recently completed first wave. NEMESIS-2 is a prospective study among Dutch-speaking subjects aged 18-64 years from the general Dutch population. Its baseline wave included 6646 subjects. Three waves are planned with three year-intervals between the waves. A multistage, stratified random sampling procedure was applied. The baseline wave of NEMESIS-2 was performed between November 2007 and July 2009. Face-to-face interviews were administered with the Composite International Diagnostic Interview (CIDI) 3.0. The response rate was 65.1%, and 76.4% of the respondents donated saliva. The sample was reasonably nationally representative, but younger subjects were somewhat underrepresented. In conclusion, we were able to build a comprehensive dataset of good quality, permitting several topics to be studied in the future.
Novel approach for narrowband superconducting filters (2003)

The concept and latest experimental results for planar bandpass filters made from high temperature superconductors (HTS) are reported. In the proposed approach, coupling between adjacent resonators is provided by "disturbing" the resonator symmetry. This allows the realization of very narrowband filters with closely spaced resonators. Furthermore, filter parameters can be trimmed in a much wider range (including sign of coupling) then in conventional structures. Results for several quasi-elliptic filters for mobile communication base stations are presented.
Epoxidation of Diosgenin, 25(R)-1,4,6-Spirostatrien-3-one and 25(R)-4,6-Spirostadien-3β-ol (2003)

Upon treatment of 25(R)-spirost-5-en-3β-ol (diosgenin), 25(R)-1,4,6-spirostatrien-3-one and 25(R)-4,6-spirostadien-3β-ol with 30% H2O2 and 5% NaOH in methanol, diosgenin did not react, 25(R)-1,4,6-spirostatrien-3-one was converted to 25(R)-1α,2α-epoxy-4,6-spirostadien-3-one and 25(R)-4,6-spirostadien-3β-ol was oxidized to give a small amount of 25(R)-4,6-spirostadien-3-one, while most of the original starting material remained unchanged. On the other hand, reactions of diosgenin, 25(R)-1,4,6-spirostatrien-3-one and 25(R)-4,6-spirostadien-3β-ol with m-chloroperoxybenzoic acid in chloroform yielded 25(R)-5α,6α-epoxyspirostan-3β-ol, 25(R)-6α,7α-epoxy-1,4-spirostadien-3-one and 25(R)-4β,5β-epoxy-6-spirosten-3β-ol, respectively.
Rationally Designed Dynamic Protein Hydrogels with Reversibly Tunable Mechanical Properties (2014)

Protein hydrogels have attracted considerable interest due to their potential applications in biomedical engineering. Creating protein hydrogels with dynamic mechanical properties is challenging. Here, the engineering of a novel, rationally designed protein‐hydrogel is reported that translates molecular level protein folding‐unfolding conformational changes into macroscopic reversibly tunable mechanical properties based on a redox controlled protein folding‐unfolding switch. This novel protein folding switch is constructed from a designed mutually exclusive protein. Via oxidation and reduction of an engineered disulfide bond, the protein folding switch can switch its conformation between folded and unfolded states, leading to a drastic change of protein's effective chain length and mechanical compliance. This redox‐responsive protein can be readily photochemically crosslinked into solid hydrogels, in which molecular level conformational changes (folding‐unfolding) can result in significant macroscopic changes in hydrogel's physical and mechanical properties due to the change of the effective chain length between two crosslinking points in the protein hydrogel network. It is found that when reduced, the hydrogel swells and is mechanically compliant; when oxidized, it swells to a less extent and becomes resilient and stiffer, exhibiting an up to fivefold increase in its Young's modulus. The changes of the mechanical and physical properties of this hydrogel are fully reversible and can be cycled using redox potential. This novel protein hydrogel with dynamic mechanical and physical properties could find numerous applications in material sciences and tissue engineering.
A INFLUÊNCIA DAS DIFERENTES PRÁTICAS ESPORTIVAS NO DESENVOLVIMENTO MOTOR EM CRIANÇAS (2012)

O desenvolvimento motor e essencial para que o individuo, no decorrer da vida, utilize de padroes e habilidades motoras para sua sobrevivencia, tais como andar, correr, chutar, pular, alcancar, dentre outras. Acredita-se que estimulacoes a praticas esportivas durante a infância, priorizam esse aprendizado, desenvolvendo movimentos e habilidades fundamentais para sua vida. O objetivo do estudo foi analisar se a pratica de diferentes esportes influencia diretamente no desenvolvimento motor e na aptidao fisica das mesmas. A metodologia e descritiva comparativa. Foram submetidas 60 criancas do sexo feminino de 7 a 10 anos, escolares, distribuidas em 6 grupos (10 de atletismo, 10 de futsal, 10 de voleibol, 10 de handebol, 10 de natacao e 10 que pratiquem apenas a educacao fisica escolar) a dois testes motores: TGMD-2 e PROESP-BR. Participaram em trajes de esporte e foram filmadas na realizacao. Para avaliacao das imagens o software utilizado foi o EASY TGMD2. As imagens foram destruidas apos analise. O resultado apresentou diferenca estatisticamente significativa para os padroes agilidade (p=0,039), forca explosiva de membros inferiores (p=0,008), padrao de corrida (p=0,010), padrao manipulativo de agarrar uma bola (p=0,003), padrao de chutar uma bola (p=0,003) e arremessar uma bola (p=0,002). Para as outras variaveis nao foram identificadas diferencas estatisticamente significativa entre os grupos de praticantes, bem como os nao praticantes de esportes. Portanto a escolha da modalidade esportiva nao necessariamente e feita de acordo com suas caracteristicas morfologicas, porem, o desenvolvimento locomotor, manipulativo e a aptidao fisica fazem relacao direta com o esporte treinado, ou seja, a crianca desenvolve melhor padroes de movimentos utilizados no esporte que pratica, assim como os padroes menos utilizados, sao menos desenvolvidos. Palavras-chave: desempenho motor, iniciacao esportiva, infância.
A provisioning model towards OAuth 2.0 performance optimization (2011)

A major hurdle of formal adoption of OAuth protocol for enterprise applications is performance. Enterprise applications (e.g. SAP, SharePoint, Exchange Server, etc.) require a mechanism to predict and manage performance expectations. As these applications become more and more ubiquitous in the Cloud, the scale and performance expectations become an important factor impacting architectural decisions for security protocol adoption. This paper proposes an optimization to OAuth 2.0 for enterprise adoption. This optimization is achieved by introducing provisioning steps to pre-establish trust amongst enterprise applications' Resource Servers, its associated Authorization Server and the clients interested in access to protected resources. In this model, trust is provisioned and synchronized as a pre-requisite step to authentication and authorization amongst all communicating entities in OAuth protocol, namely, the client requesting a protected resource, the resource server, and the authorization server. For a case study, we analyze SAP authenticating with SharePoint using our optimization versus existing OAuth protocol. We believe such optimization will further facilitate the adoption of OAuth in the enterprise where scale and performance are critical factors.
Some Preamble Design Aspects in CP-OFDM Systems (2012)

A fundamental problem in training-based channel estimation for various communication systems is the preamble design. Two crucial aspects in such a design are the achievable mean square error (MSE) and the corresponding peak-to-average power ratio (PAPR). In this letter, preamble-based least squares (LS) channel estimation in CP-OFDM systems is considered. Ignoring the PAPR aspect, several MSE-optimal preambles and a necessary condition for their existence are presented. To this end, a training energy constraint, containing also the energy spent to the cyclic prefix (CP), is imposed. This constraint differs from the usual training energy constraints in the existing literature, which ignore the CP energy during training. These preambles contribute in the completion of existing results concerning MSE-optimal preambles in CP-OFDM systems. However, since high PAPR is an issue concerning these optimal designs, we show how these MSE-optimal preambles can be combined with the usual Zadoff-Chu (ZC) sequences to enlarge the class of PAPR-optimal preambles that achieve good MSE performance at the same time.
Ambient sulfate aerosol deposition in man: modeling the influence of hygroscopicity. (1985)

Atmospheric sulfate aerosols [H2SO4, (NH4)2SO4, and NH4HSO4] are of international concern because of their global prevalence and potential irritant or toxic effects on humans. To assess hazards following inhalation exposure, the total dose delivered to the human respiratory tract and its regional distribution must be determined. The mass median aerodynamic diameter of the inhaled aerosol will influence the sites of deposition in the respiratory tract. Atmospheric sulfate aerosols are hygroscopic and will have changing particle sizes and densities as they absorb water vapor in the humid environment of the human respiratory tract. Experimental and theoretical data that describe particle size as a function of temperature and relative humidity were used in computer subroutines of an aerosol deposition model in order to calculate the dose dispersion of H2SO4, (NH4)2SO4, and NH4HSO4 aerosols in man. Different temperature and relative humidity environments that approximately correspond to nasal and oral breathing were studied. The predicted deposition patterns are very different from those of nonhygroscopic aerosols with identical inhaled mass median aerodynamic diameter values.
Microbial composition of chlorinated ethene-degrading cultures dominated by Dehalococcoides (2006)

The community composition of microbial cultures degrading tetrachloroethene (PCE), trichloroethene (TCE), cis-1,2-dichloroethene (cDCE) and vinyl chloride (VC) to ethene was studied. A combination of PCR-denaturing gradient gel electrophoresis (PCR-DGGE) and 16S rRNA gene sequence analysis revealed that all cultures contained Dehalococcoides populations, but that the populations of other organisms varied widely. Based on the sequences of cloned 16S rRNA genes, real-time PCR methods were developed for several of these phylotypes affiliated with the putative dechlorinators Sulfurospirillum and Geobacter, the putative methanogens Methanomethylovorans, Methanomicrobiales, Methanosaeta and Methanosarcina, the putative acetogens Acetobacterium, Spirochaetes, and Sporomusa, and the putative fermenters Bacteroidetes, Syntrophus, and Syntrophobacter. These novel quantitative PCR methods were then used to estimate relative abundances of each phylotype in several individual cultures maintained on each chlorinated ethene. Dehalococcoides populations were the dominant phylotypes assayed in most KB-1 cultures, agreeing with the DGGE and cloning results. A Geobacter phylotype was also strongly represented in most PCE and TCE cultures, but not in cDCE or VC cultures, suggesting a possible role for this organism as a PCE-to-cDCE dechlorinator. The Sulfurospirillum phylotype was estimated to comprise a minor fraction of 16S rRNA gene copies and did not appear to have an important role in dechlorination.
A computerized system for the analysis of cardiac rhythm and conduction (2002)

An effective system for monitoring of cardiac rhythm and conduction disturbances is discussed. The system permits: diagnosis of 8 types of rhythm disturbances and 4 types of conduction disturbances; performance of parallel around-the-clock monitoring of 8 patients; emitting alarms for asystole, bradycardia and tachycardia; prediction and prevention of the development of acute disturbances; and it allows monitoring of pharmacological effects. The system operates on computers compatible with IBM PC/AT. The monitoring results are given to physicians for further analysis and decision making. The online information input is realized in this system. The system is especially valuable for complex arrhythmias combined with conduction disturbances.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
AUC-based biomarker ensemble with an application on gene scores predicting low bone mineral density (2011)

Supplementary data are available at Bioinformatics online.
Stable inversions for complete moment tensors (2008)

The seismic moment tensors for certain types of sources, such as volcanic earthquakes and nuclear explosions are expected to contain an isotropic component. Some earlier efforts to calculate the isotropic component of these sources are flawed due to an error in the method of Jost & Herrmann. We corrected the method after Herrmann & Hutchensen and found great improvement in the recovery of non-double-couple moment tensors that include an isotropic component. Tests with synthetic data demonstrate the stability of the corrected linear inversion method, and we recalculate the moment tensor solutions reported in Dreger et al. for Long Valley caldera events and Dreger & Woods for Nevada Test Site nuclear explosions. We confirm the findings of Dreger et al. that the Long Valley volcanic sources contain large statistically significant isotropic components. The nuclear explosions have strikingly anomalous source mechanisms, which contain very large isotropic components, making it evident that these events are not tectonic in origin. This indicates that moment tensor inversions could be an important tool for nuclear monitoring.
Disconnection of electroencephalographic, motoric, and cardiac evidence of ECT seizure. (1996)

Three electroconvulsive therapy (ECT) stimuli of increasing dosage were applied sequentially under one anesthesia to each of two patients. With each, the first produced intense electroencephalogram (EEG) seizure activity with a sharp endpoint but no motoric activity and little heart rate elevation. The second produced 15-21 s of tonic-clonic activity with negligible seizure activity on the EEG monitor and little heart rate increase. The third produced typical motoric, EEG, and heart rate signs of seizure. These observations indicate that the signs of high EEG amplitude, sharp EEG endpoint, distinct postictal suppression, and tonic-clonic activity can appear in seizures of questionable quality and weak generalization through the brain. Consequently, none of these characteristics by themselves indicate good quality or seizure generalization, and ECT monitoring is incomplete without considering all of them along with peak heart rate.
E-learning Applications in Multimedia: A Review (2019)

Multimedia and networking technologies have had a significant impact on our everyday activities, particularly as regards how all learn. technologies have facilitated the provision of a web-based virtual classroom environment by promoting teacher-student and student-student communication to transform the modern education system according to current needs, course material delivery, and online student assessments. They give the students more control over their schedule and speed of learning. In addition to this, E-learning systems now provide various media types for students to suit their learning preferences, leading to changes in their learning effectiveness. Interactive multimedia offers learners various types of media to suit their learning style, customizes the delivery of digital content that increases learning performance. In this chapter, the quality of knowledge can be enhanced by multimedia-based methods and strategies are explored, as well as the negative and positive effects of using interactive multimedia for learners. This extended presentation explores the new multimedia-specific E-learning developments from both pedagogical and technical viewpoints, their research challenges and future trends. This research covers Digital Tools for e-learning, social networks as an e-learning tool, and efficacy and experience.
Ulnar Nerve Pressure  (1999)

Extrapolating these results to the clinical setting, the supinated arm position is likely to minimize pressure over the ulnar nerve. With the forearm in neutral orientation, pressure over the ulnar nerve decreases as the arm is abducted between 30 degrees and 90 degrees. In addition, up to one half of male patients may fail to perceive or experience clinical symptoms of ulnar nerve compression sufficient to elicit SSEP changes.
Experience with chloramines as primary disinfectants (1981)

For more than 50 years chloramines have been used at the Philadelphia Suburban Water Company's Pickering Creek water treatment plant. During this period chloramination has reduced the coliform count in the raw water from values as high as 100 000 organisms/mL to nearly zero in the finished water.