gebhart/patrepeval huggingface dataset:
Characterization and quantitation of soybean proteins in commercial soybean products by capillary electrophoresis (1999)

Capillary electrophoresis was applied for the first time to determine soybean proteins in commercial soybean products. The most suitable conditions for the analysis of these products in less than 7 min were 0.05 M phosphate buffer (pH 8) with 1 M urea; detection wavelength, 254 nm; applied voltage, 20 kV; and temperature, 30 degrees C. Quantitation of soybean proteins was achieved using referenced conditions by means of the method of standard additions, using as standard a soybean protein isolate. This method was validated and applied to the quantitation of soybean proteins in commercial products derived from soybean protein isolate and soybean seeds.
Solubility of CaSO<sub>4</sub>, Phases in Aqueous HCl + CaCl<sub>2</sub> Solutions from 283 K to 353 K. (2006)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access the actual ChemInform Abstract, please click on HTML or PDF.
Non-chemically amplified resists for 193 nm lithography (2008)

Acid diffusion during the post-exposure bake of chemically amplified resists (CARs) is a major contributing factor to line width roughness (LWR) and resolution limits at the 32 nm node and beyond. To overcome these limitations, non-CAR materials are becoming more attractive because acid diffusion is eliminated. We have therefore focused our effort on the synthesis of copolymers that have both a diacyldiazo side chain unit as well as a hexafluoroalcohol unit. This copolymer shows better contrast than that of copolymers containing lactone units due to their inhibition behavior. Furthermore, polymer blends containing hexafluoroalcohol groups show good 100 nm line and space patterning property for 193 nm lithography. This paper describes the design, synthesis, and characterization of these non-CARs, and thier improvement to photolithography.
Verification of phylogenetic predictions <i>in vivo</i> and the importance of the tetraloop motif in a catalytic RNA (1999)

M1 RNA, the catalytic subunit of Escherichia coli RNase P, forms a secondary structure that includes five sequence variants of the tetraloop motif. Site-directed mutagenesis of the five tetraloops of M1 RNA, and subsequent steady-state kinetic analysis in vitro, with different substrates in the presence and absence of the protein cofactor, reveal that (i) certain mutants exhibit defects that vary in a substrate-dependent manner, and that (ii) the protein cofactor can correct the mutant phenotypes in vitro, a phenomenon that is also substrate dependent. Thermal denaturation curves of tetraloop mutants that exhibit kinetic defects differ from those of wild-type M1 RNA. Although the data collected in vitro underscore the importance of the tetraloop motif to M1 RNA function and structure, three of the five tetraloops we examined in vivo are essential for the function of E. coli RNase P. The kinetic data in vitro are not in total agreement with previous phylogenetic predictions but the data in vivo are, as only mutants in those tetraloops proposed to be involved in tertiary interactions fail to complement in vivo. Therefore, the tetraloop motif is critical for the stabilization of the structure of M1 RNA and essential to RNase P function in the cell.
FERTILITY AND MEIOTIC BEHAVIOUR IN TETRAPLOID BARLEY (1975)

Chromosome pairing at metaphase I and distribution at anaphase I were examined in 3 autotetraploid and 3 amphidiploid parents and their F 1 hybrids and related to spike fertility of the respective plants. Structural differences translocated from the Hordeum leporinum chromosomes to H. vulgare did not significantly enhance preferential pairing and subsequent fertility in the latter as anticipated. Quadrivalent formation was not related but regular disjunction at anaphase I was related to spike fertility.
High Temperature Oxidation Behavior of Si-bearing Ferritic Stainless Steels in Humidified Atmosphere (1996)

Effect of Cr and Si contents in the ferritic stainless steels on the occurrence of reddish brown oxide scale in the kerosene-combustion atmospheres has been studied in the O2+H2O+Ar mixed gases and the combustion portions of kerosene heaters. Furthermore, their effects have been studied in detail by the observation and analysis of the produced oxide scales. In the results, the oxidation behaviour of Cr steels in the O2+H2O+Ar mixtures showed good coincidence with those in the kerosene heaters. Namely, Cr and Si show good effect to prevent the formation of the reddish brown oxide scale. It was found that this good effect can be attained by increasing Cr and Si in the steel following a condition Cr(%)+4Si(%)≥27. When a reddish brown oxide scale occurs, (Cr, Fe)3O4 as well as (Cr, Fe)2O3 was produced in the initially formed oxide scale. In order to prevent the formation of the reddish-brown oxide scale, it was found that the initially formed oxide scale must be M2O3 type which can be attained by the highly Cr-enriched scale (Cr/Fe ratio≥3). Furthermore, Si may enrich Cr in the scale and prevent the oxidation of Fe.
Analyzing power in CNI-region at AGS (experiment E950) (2000)

Acceleration of polarized protons is one of the exciting features of the new Relativistic Heavy Ion Collider (RHIC) at Brookhaven National Laboratory. Measurements of beam polarization are required both for experiments and the accelerator tuning. Elastic scattering in the Coulomb nuclear interference (CNI) region of polarized proton beams on a carbon target demonstrates asymmetry which can be used to build a polarimeter. The methods proposed for a RHIC CNI polarimeter were tested with the AGS polarized beam in the E950 experiment. A 21.7 GeV/c polarized proton beam was scattered on an extremely thin carbon ribbon target located in the AGS ring. Two symmetrical arms consisting of silicon strip detectors (SSD) and a micro channel plate (MCP) were used to identify recoil carbon. Data obtained demonstrates a good identification of the reaction by the apparatus and a significant analyzing power. A RHIC polarimeter setup with 4 SSDs but without MCPs will be used to commission RHIC with polarized protons and for the first spin physics running in 2001.
Dioxirane Oxidations of Compounds other than Alkenes (2008)

Abstract Epoxidations, heteroatom oxidations, and Y‐H insertions constitute the best investigated oxidations by dioxiranes. This article concerns epoxidation of the double bonds in the cumulenes, such as allenes, acetylenes, and arenes; the oxidation of heteroatom functionalities, mainly lone pairs on sulfur, on nitrogen, and on oxygen as the deoxygenation of N‐ oxides; the oxidation of C = Y functionalities, Y‐H insertions such as in C‐H alkanes, and Si‐H silanes; and the oxidation of organometallic substrates including metal and ligand‐sphere oxidation.
Development of Cognitive Interventional Therapy Program for Mild Cognitive Impairment: Preliminary Study (2022)

Objective: Mild cognitive impairment (MCI) is considered a pre-stage of dementia. This study aims to develop a cognitive intervention treatment program (CITP) as a non-pharmacological therapy, apply this program into MCI patients, and examine patients’ changes in cognitive function. Methods: Among 16 patients with MCI, 10 patients were randomly assigned to the experimental group and 6 patients were assigned into the control group. The patients assigned to the experimental group participated in the CITP once a week for a period of 15 weeks. The control group were suggested to live a normal daily life without CITP given. After 15 weeks (3 months), pre- and post-investigations, such as cognitive function test, emotional test, brain oxygen saturation test, were conducted and compared for each group. Results: The cognitive function scores and the brain oxygen saturation levels taken during the Verbal Fluency Test showed a statistically significant difference between those of experimental and the control groups. To be specific, while the cognitive function score improved in the experimental group, there was a decline in the control group. There was no statistically significant difference in emotional changes between two groups. Looking at the changes within each group, the overall cognitive function score of the experimental group was significantly increased, but no pre- and post-significantly changes were observed in brain oxygen saturation activation. On the other hand, the control group showed a statistically significant decline in the attention criteria of the cognitive functional areas, and no statistically significant changed in brain activation. Conclusion: The result from this study has given some promising views on maintaining and improving the deteriorating cognitive function in patients with MCI. Conducting CITP on patients is expected to strengthen the neural network. Eventually, there would be a less deterioration of cognitive function and less progression of MCI into dementia.
Integration of gene expression data with prior knowledge for network analysis and validation (2011)

This construction involved as a crucial step the passage to a mammalian protein identifier format as well as to a reaction-based semantics of metabolism. This yielded good connectivity but also led to the need to perform benchmark tests to exclude loss of essential information. Such validation, albeit tedious due to limitations of existing methods, turned out to be informative, and in particular provided biological insights as well as information on the degrees of coherence of the networks despite fragmentation of experimental data.Key node analysis exploited the networks for potentially interesting proteins in view of drug target prediction.
Direct Synthesis of Single-Walled Carbon Nanotubes on Silicon and Quartz-Based Systems (2004)

A newly developed technique of synthesizing single-walled carbon nanotubes (SWNTs) directly on the surface of Si and quartz substrates is introduced in this report. This technique adopted a liquid-based dip-coating method to mount a very small amount of catalyst metals on the surface of substrates using Mo/Co bimetallic acetate solution. The merits of this approach lie in its easy, costless, and geometry-flexible nature compared with conventional sputtering and deposition approaches. We used the alcohol catalytic chemical vapor deposition (ACCVD) method that can produce relatively high-quality SWNTs even at low temperatures down to 600°C. This low-temperature process contributes to the prevention of the agglomeration of catalytic metals on the surface and chemical reaction between catalytic metal and silicon, which helps us to eliminate any kind of intermediating support materials. Thereby synthesized SWNTs on Si and quartz substrates under various CVD conditions are characterized by means of SEM, TEM, Raman scattering, and optical absorbance measurements. The underlying reasons our experimental procedure and choice of catalyst worked for the synthesis of SWNTs are discussed through comparative studies. At the end of this report, some possible applications of this technique are stated.
Seismic Velocity Monitoring Using Cabled Seafloor and Borehole Seismic Observatories in the Nankai Trough, Japan (2019)

We used ambient noise records observed by DONET seafloor seismometer and LTBMS borehole seismometers to monitor seismic velocity structure along the Nankai Trough subduction zone. Seismic interferometry, which can produce zero offset pseudo shot records by calculating auto- and cross-correlation function from ambient noise records, was used. We applied the seismic interferometry method to the ambient noise records observed by DONET and LTBMS seismometers from June to Sep. 2016. We also applied stretch interpolate technique to detect temporal change of seismic velocity during the period. Results suggest that DONET data with seismic interferometry method can detect less than 0.5% velocity changes below seafloor and LTBMS data can also detect much smaller velocity change which may occur during SSE. These results imply a possibility for this technique to be used as seismic structure monitoring tool without any artificial seismic sources.
Sediment Formation in Catalytically Cracked Distillate Fuel Oils (1957)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSediment Formation in Catalytically Cracked Distillate Fuel OilsR. D. Offenhauer, J. A. Brennan, and R. C. MillerCite this: Ind. Eng. Chem. 1957, 49, 8, 1265–1266Publication Date (Print):August 1, 1957Publication History Published online1 May 2002Published inissue 1 August 1957https://pubs.acs.org/doi/10.1021/ie50572a032https://doi.org/10.1021/ie50572a032research-articleACS PublicationsRequest reuse permissionsArticle Views63Altmetric-Citations21LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
DNA ligand designed to antagonize EBNA1 represses Epstein–Barr virus‐induced immortalization (2011)

Epstein-Barr virus (EBV) transforms human B lymphocytes into immortalized cells in vitro and is associated with various malignancies in vivo. EBNA1, which is expressed in the majority of EBV-infected cells, recognizes specific DNA sequences at the cis-acting latent origin of plasmid replication (oriP) element of the EBV genome. EBNA1 plays a critical role in the viral episome maintenance and transactivates viral transforming genes in latently infected cells. Therefore, DNA-targeting agents that can disrupt the EBNA1-oriP interaction will offer novel functional inhibitors of EBNA1. Pyrrole-imidazole polyamides, sequence-specific DNA ligands, can be designed to interfere with the binding of various transcriptional factors. Here, we synthesized pyrrole-imidazole polyamides targeting EBNA1-bound DNA sequences and developed an inhibitor for the EBNA1-oriP interaction. A pyrrole-imidazole polyamide, designated as DSE-3, bound adjacent to the EBNA1 recognition sequences located in the dyad symmetry element of oriP, and selectively inhibited EBNA1-oriP binding both in vitro and in vivo. DSE-3 also inhibited the proliferation of established lymphoblastoid cell lines by eradicating EBV episomes from the cells. In addition, DSE-3 repressed the expression of viral transforming genes after infecting human peripheral blood mononuclear cells with EBV and, as a consequence, inhibited EBV-mediated B-cell immortalization. These results suggest that EBNA1 functions will be an attractive pharmacological target for EBV-associated diseases.
Sleep Disturbance After Mild Traumatic Brain Injury: Indicator of Injury? (2011)

Mild traumatic brain injury (mTBI) is a complex entity with no known objective diagnostic markers. To test the hypothesis that sleep disturbances in the acute mTBI period can serve as an indicator of brain injury, the authors compared sleep polysomnograms (PSG) and sleep EEG power spectra (PS) data in seven mTBI subjects with seven age- and race-matched healthy-control subjects. The two groups differed significantly on PS measures, suggesting that mTBI can result in a disruption of sleep microarchitecture and, in theory, could be of use as a marker for brain injury. These pilot findings need to be replicated on larger samples.
Objects to the rescue! or <i>httpd</i> : the next generation operating system (1995)

This position paper suggests that object-oriented operating systems may provide the means to meet the ever-growing demands of applications. As an example of a successful OOOS, we cite the http daemon. To support the contention that httpd is in fact an operating system, we observe that it implements uniform naming, persistent objects and an invocation meta-protocol, specifies and implements some useful objects, and provides a framework for extensibility.We also believe that the modularity that is characteristic of OO systems should provide a performance benefit rather than a penalty. Our ongoing work in the Synthetix project at OGI is exploring the possibilities for advanced optimizations in such systems.
Increased nonoxidative glycolysis despite continued fatty acid uptake during demand-induced myocardial ischemia (2002)

During stress, patients with coronary artery disease frequently fail to increase coronary flow and myocardial oxygen consumption (MVO(2)) in response to a greater demand for oxygen, resulting in "demand-induced" ischemia. We tested the hypothesis that dobutamine infusion with flow restriction stimulates nonoxidative glycolysis without a change in MVO(2) or fatty acid uptake. Measurements were made in the anterior wall of anesthetized open-chest swine hearts (n = 7). The left anterior descending (LAD) coronary artery flow was controlled via an extracorporeal perfusion circuit, and substrate uptake and oxidation were measured with radiotracers. Demand-induced ischemia was produced with intravenous dobutamine (15 microg x kg(-1) x min(-1)) and 20% reduction in LAD flow for 20 min. Despite no change in MVO(2), there was a switch from lactate uptake (5.9 +/- 3.1) to production (74.5 +/- 16.3 micromol/min), glycogen depletion (66%), and increased glucose uptake (105%), but no change in anterior wall power or the index of anterior wall energy efficiency. There was no change in the rate of tracer-measured fatty acid uptake; however, exogenous fatty acid oxidation decreased by 71%. Thus demand-induced ischemia stimulated nonoxidative glycolysis and lactate production, but did not effect fatty acid uptake despite a fall in exogenous fatty acid oxidation.
The Biomechanical and Biochemical Properties of Swine Tendons — Long Term Effects of Exercise on the Digital Extensors (1980)

Positive effects on the tensile characteristics of swine digital extensors were found following twelve months of exercise training. Compared to sedentary controls, the tendons from the exercised animals became stronger as a material and exhibited hypertrophy. These biomechanical results were supported by biochemical analyses of tendon composition. Exercise increased the concentration of collagen as well as the total weights of the tendons. For determining stress and strain in tendon material, we used specially designed instruments to measure the tendon cross-sectional area, and a video dimensional analyzer system to measure accurately its "non-contact" tensile strain. With these newly developed apparatus, the mechanical properties of the tendons were accurately determined so that the effects of exercise training could be compared.
Potential fungicidal activity of 3-(substituted oxy)-5-methylisoxazoles (2013)

The structure of the commercial fungicide hymexazol, 3-hydroxy-5-methylisoxazol, was transformed to acyloxy, 3-alkoxy, alkylcarbamoyloxy and acylamino derivatives, and their antifungal activities or disease control activities were examined. The 3-acyloxy derivatives were much more active than the other derivatives, and some of the 3-acyloxy derivatives exhibited antifungal activities or disease control activities against a wide range of pathogens, such as Pyrenophora graminea, Alternaria alternata, Cercospora beticola, Rhynchosporium secalis, Septoria tritici, Microdochium nivale, Rhizoctonia solani, Puccinia recondita, and Blumeria graminis. Among them, 5-methyl-3-isoxazolyl (α)-naphthoate and (o)-toluate and 2,2-dichloro-1,3,3-trimethylcyclopropanecarboxylate completely inhibited the mycelial growth of Rhizoctonia solani and M. nivale at 25 mg/L, respectively.
Comparative efficacy and safety of cefprozil and amoxycillin/clavulanate in the treatment of acute otitis media in children (1994)

Cefprozil is a new oral cephalosporin with activity against the most common pathogens isolated in acute otitis media. This randomized study enrolled 361 patients (mean age 29 months). Physical examination and culture via tympanocentesis were required less than 48 h before therapy. One hundred and ninety-one patients were evaluable for clinical efficacy; 99 received cefprozil (20 mg/kg/day bd) and 92 received amoxycillin/clavulanate (13.3 mg/kg/day tid). Duration of treatment was 7-9 days for 81 patients, 10 days for 105 patients and 11-16 days for five patients. The treatment groups were comparable with respect to demographics, severity of infection and number of previous episodes. Clinical evaluations of efficacy were based on physical examination including otoscopy within a 14 day period after therapy. Satisfactory clinical responses were achieved in 84% of cefprozil-treated patients and 87% of amoxycillin/clavulanate-treated patients. Pathogens most commonly isolated included Haemophilus influenzae (33%) and Streptococcus pneumoniae (22%). All 361 patients were evaluable for safety. Adverse clinical events were reported in 13% (24) of cefprozil-treated patients and 20% (36) of amoxycillin/clavulanate-treated patients. Cefprozil, administered twice a day, is comparable to a regimen of amoxycillin/clavulanate three times a day in the treatment of acute otitis media in children.
Rapid Direct Determination of Low and High Molecular Weight Kininogen in Human Plasma by Particle Concentration Fluorescence Immunoassay (PCFIA) (1997)

In this study, we employed Particle Concentration Fluorescence Immunoassay (PCFIA), for directly measuring both high and low molecular weight kininogens (HK and LK) in human plasma. In 38 normal donors, the mean values for plasma kininogens were 93 mg/ml +/- 19 SD, 82 mg/ml +/- 12 SD, and 175 mg/ml +/- 29 SD, respectively for LK, HK, and TotK (the sum of LK and HK detected by their common heavy chains). Plasma completely deficient in HK and LK was unreactive (< 0.25 mg/ml) in all 3 assays whereas plasma from a patient with Fitzgerald Trait had an HK value of 11 mg/ml, an LK value of 36 mg/ml and a TotK value of 59 mg/ml. The reagents can be prepared in advance and all three kininogen determinations can be performed, using the same diluted sample on 24 plasma samples, in triplicate, or 40 plasma samples, in duplicate, in less than 1 h. By performing all 3 kininogen determinations, it is possible to differentiate cleaved from intact kininogens. This technique will facilitate the widespread screening of kininogen levels in biological fluids of normal humans as well as of patients with various diseases.
Thyrocalcitonin Inhibition of Bone Resorption Induced by Parathyroid Hormone in Tissue Culture (1966)

Added thyrocalcitonin greatly diminished parathyroid-hormone-induced resorption of bone in tissue culture. The results indicate that bone is primary site of action of thyrocalcitonin.