gebhart/patrepeval huggingface dataset:
Current-voltage characteristics of MBE-grown strained Si1-xGex/Si heterojunction diodes and their temperature dependence (1990)

Studies of current-voltage (I-V) characteristics and their temperature dependence show that the current transport in MBE-grown Si1-xGex/Si diodes is closely related to the epitaxial film quality. It is mainly controlled by two different mechanisms at low and high temperature. The ideality factor n of the diodes increases as the temperature is reduced, and n increases faster for the diodes which have larger n at room temperature. From comparisons with calculated results, it is proposed that the transport mechanism is diffusion controlled at high temperature and defect-assisted tunneling controlled at low temperature. The results from ? irradiation studies also support this suggestion. Due to the existence of band-offsets, the shift of the I-V curve with temperature of p+-Si1-xGex/n-Si diodes is much smaller than that in n+-Si1-xGex/p-Si diodes, when the current is diffusion controlled. The band-offsets are estimated from these shifts, and the results are in agreement with values measured by another method.
PERIARTERIAL SYMPATHECTOMY (1925)

From the service of Dr. Charles A. Elsberg, at Mount Sinai Hospital, and the author's service at the Montcfiorc Hospital.
Compact static Fourier transform spectrometer in glass integrated optics in the NIR and visible domain (2012)

The characterization of a Leaky Loop Integrated Fourier Transform Spectrometer (LLIFTS) in integrated optics is described in the visible and the near infrared spectral domain. The device is realized using ion-exchange technology in a glass substrate. LLIFTS is compact, costless with no moveable parts. Its principle consists in a two beam interferometer in planar design using a leaky loop waveguide structure. The advantage of the design of the LLIFTS structure is to control the shape of the interference pattern in order to measure a high contrast and fringe spacing well sampled by a 2048 pixels camera directly at the output of the component. Spectral resolution of 7nm at 1500nm and 2nm at 633nm are obtained.
Abnormal polyunsaturated fatty acid patterns of serum lipids in alcoholism and cirrhosis: arachidonic acid deficiency in cirrhosis. (1985)

Patterns of polyunsaturated fatty acids of serum phospholipids were measured for groups of alcoholics without cirrhosis, alcoholics with cirrhosis, cirrhotics without alcoholism, and a control population. Alcoholics without cirrhosis showed increased polyunsaturated fatty acids derived from linoleic and linolenic acids, but in cirrhotics these products were decreased. Alcoholism accentuated the abnormal polyunsaturated fatty acid pattern of cirrhosis. In alcohol abuse without cirrhosis, the level of 20:3 omega 9 (20 acyl carbon atoms:3 double bonds, omega, 9 carbon atoms beyond last double bond) was significantly increased, despite adequate levels of linoleic and arachidonic acids. Liver involvement appears necessary for development of deficiencies of polyunsaturated fatty acids in serum phospholipids, of which arachidonic acid deficiency is of the largest magnitude.
Overexpression of glycogen phosphorylase increases GLUT4 expression and glucose transport in cultured skeletal human muscle (1998)

Skeletal muscle glucose utilization, a major factor in the control of whole-body glucose tolerance, is modulated in accordance with the muscle metabolic demand. For instance, it is increased in chronic contraction or exercise training in association with elevated expression of GLUT4 and hexokinase II (HK-II). In this work, the contribution of increased metabolic flux to the regulation of the glucose transport capacity was analyzed in cultured human skeletal muscle engineered to overexpress glycogen phosphorylase (GP). Myocytes treated with an adenovirus-bearing muscle GP cDNA (AdCMVMGP) expressed 10 times higher GP activity and exhibited a twofold increase in the Vmax for 2-deoxy-D-[3H]glucose (2-DG) uptake, with no effect on the apparent Km. The stimulatory effect of insulin on 2-DG uptake was also markedly enhanced in AdCMVMGP- treated cells, which showed maximal insulin stimulation 2.8 times higher than control cells. No changes in HKII total activity or the intracellular compartmentalization were found. GLUT4, protein, and mRNA were raised in AdCMV-MGP-treated cells, suggesting pretranslational activation. GLUT4 was immunodetected intracellularly with a perinuclear predominance. Culture in glucose-free or high-glucose medium did not alter GLUT4 protein content in either control cells or AdCMV-MGP-treated cells. Control and GP-overexpressing cells showed similar autoinhibition of glucose transport, although they appeared to differ in the mechanism(s) involved in this effect. Whereas GLUT1 protein increased in control cells when they were switched from a high-glucose to a glucose-free medium, GLUT1 remained unaltered in GP-expressing cells upon glucose deprivation. Therefore, the increased intracellular metabolic (glycogenolytic-glycolytic) flux that occurs in muscle cells overexpressing GP causes an increase in GLUT4 expression and enhances basal and insulin-stimulated glucose transport, without significant changes in the autoinhibition of glucose transport. This mechanism of regulation may be operative in the postexercise situation in which GLUT4 expression is upregulated in coordination with increased glycolytic flux and energy demand.
High Throughput Biological Analysis Using Multi-bit Magnetic Digital Planar Tags (2008)

We report a new magnetic labelling technology for high‐throughput biomolecular identification and DNA sequencing. Planar multi‐bit magnetic tags have been designed and fabricated, which comprise a magnetic barcode formed by an ensemble of micron‐sized thin film Ni80Fe20 bars encapsulated in SU8. We show that by using a globally applied magnetic field and magneto‐optical Kerr microscopy the magnetic elements in the multi‐bit magnetic tags can be addressed individually and encoded/decoded remotely. The critical steps needed to show the feasibility of this technology are demonstrated, including fabrication, flow transport, remote writing and reading, and successful functionalization of the tags as verified by fluorescence detection. This approach is ideal for encoding information on tags in microfluidic flow or suspension, for such applications as labelling of chemical precursors during drug synthesis and combinatorial library‐based high‐throughput multiplexed bioassays.
Scalable parallel volume raycasting for nonrectilinear computational grids (2002)

A scalable approach to parallel volume raycasting of structured and unstructured computational grids is presented. The algorithm is general enough to handle non-convex grids and cells, grids with voids, grids constructed from multiple grids, and embedded geometrical primitives. The algorithm is designed for a highly parallel MIMD architecture which features both local memory and shared memory with nonuniform access times. It has been implemented on a BBN TC2000 and benchmarked on several datasets. A variation of the algorithm which provides fast image updates for a changing transfer function is also presented. A distributed approach to controlling the execution of the volume render is used and the graphical user interface designed for this purpose is briefly described.
J043013 Study for Lifetime Prediction of Off-Axis Woven GFRP Laminate under Constant Tensile Load in Hydrothermal Environment (2012)

This study reports the off-axis delayed fracture characteristic of woven glass fiber reinforced plastics (GFRP) laminate under constant tensile load in hydrothermal environment. In this study, static tensile test and constant tensile load test were performed in air and water at 40℃. Mechanical properties of GFRP were evaluated by static tensile test. Static tensile test was conducted in water for 200, 500 and 1000 hours, to find out the effect of hydrothermal environment on mechanical properties of GFRP. Result of static tensile test, the maximum stress decreased and the strain at maximum stress decreased greatly in water. In addition, the maximum stress decreased in short term immersion and converged after 200 hours. Constant tensile load test of GFRP was conducted to investigate compliance and fracture time of GFRP. The applied stress level of constant tensile load test was determined as 15%〜75% of the maximum stress obtained from static tensile test. As the result of constant tensile load test, the compliance increased obviously and delayed fracture occurred earlier in water than air. In this study, prediction was conducted for off-axis woven GFRP laminate under constant tensile load in 40°C water using the Reiner-Weissenberg(R-W) criterion; which is based on the non-linear viscoelasticity response. The prediction data was compared well with the experimental data by considering the degradation of GFRP in 40°C water.
Study of neu-protein expression in mammary Paget's disease with and without underlying breast carcinoma and in extramammary Paget's disease. (1990)

Correlation between neu/c-erbB-2/Her-2 gene amplification and overexpression of the neu gene product has been reported in tumors of glandular origin, especially ductal breast carcinomas. Formalin-fixed and dewaxed sections from 23 cases of mammary (MPD) and 9 cases of extramammary (EPD) Paget's disease were immunohistochemically stained by means of the monoclonal antibody 3B5 directed against an intracellular domain of the neu gene protein. All MPDs exhibited a distinct membrane staining of tumor cells independent of the presence of ductal breast carcinomas found in 18 cases. All these breast carcinomas also were positive for neu staining. In contrast to MPD, all EPDs were negative. Normal epidermis was always negative. Northern blot analysis sustained the immunohistologic findings in that the presence of neu mRNA could be demonstrated in two of three cases with MPD. Negativity in one case was due to dilution effects by nontumor cells. Our results suggest that Paget cells of mammary and extramammary localization, although very similar phenotypically, derive from different genetic accidents. Furthermore neu positivity in all MPDs and all underlying ductal carcinomas suggests common genetic alterations for both tumors. However the finding of five neu protein-positive MPDs without associated ductal breast carcinomas may suggest a somewhat different transformation process.
Report from the 3rd International Workshop on Replication in Empirical Software Engineering Research (RESER 2013) (2014)

The RESER workshop provides a venue in which empirical software engineering researchers can discuss the theoretical foundations and methods of replication, as well as present the results of specific replicated studies. In 2013, the workshop co-located with the International Symposium on Empirical Software Engineering and Measurement (ESEM) in Baltimore, Maryland. In addition to several outstanding paper sessions, highlights of the 2013 workshop included a keynote address by Dr. Mel Conway, in which he presented a "45-Year Retrospective on Conway's Law and the Sociology of System Design." The workshop also featured a joint replication session exploring the results and methodologies of four research teams, who each studied some aspect of Conway's Law.
Harmonic-balance simulation of strongly nonlinear very large-size microwave circuits by inexact Newton methods (2002)

The paper introduces a new approach to harmonic-balance simulation, based on inexact Newton methods and iterative system-solving techniques. Storage and factorization of the Jacobian matrix are avoided, resulting in a dramatic drop of execution time and memory occupation. HB analyses with several tens of thousands unknowns become possible on ordinary workstations.
Investigation of Phonon Band Gap, Heat Capacity and Raman Active Phonons in BaWO[sub 4] Crystal (2010)

Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter Facebook Reddit LinkedIn Tools Icon Tools Reprints and Permissions Cite Icon Cite Search Site Citation J. Suda, P. G. Zverev; Investigation of Phonon Band Gap, Heat Capacity and Raman Active Phonons in BaWO4 Crystal. AIP Conf. Proc. 6 August 2010; 1267 (1): 1150–1151. https://doi.org/10.1063/1.3482351 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAIP Publishing PortfolioAIP Conference Proceedings Search Advanced Search |Citation Search
Production of Nucleic Acid Related Substances by Fermentative Processes (1964)

It was found that a guanine and adenine-requiring mutant of Micrococcus glutamicus accumulated the ultraviolet-absorbing substance in the culture fluid. A KY9978 strain, which accumulated the largest amount of the substance, we selected from the guanine auxotrophs derived from the guanineadenine doubleless mutant. The substance was isolated in a crystalline form from the culture fluid by the use of ion exchange resins, Diaion SA 21A and SK No. 1, and identified chemically and enzymatically as 5′-xanthylic acid, an intermediate from 5′-inosinic acid to 5′-guanylic acid on the purine nucleotide biosynthesis. A guanineless mutant of Micrococcus glutamicus, KY9978 strain, which was derived from a guanine-adenine doubleless mutant, KY9938 strain, was able to grow on guanine more abundantly than the corresponding nucleoside and nucleotide, but unable to grow On 2,6-diaminopurine. A fermentation medium most suitable for XMP production by KY9978 strain was decided by varying the concentrations and kinds of ingredients in the medium. Of particular importance in media is the concentration of guanine, the excessive addition of which decreased XMP yields remarkably. This might suggest negative feed back mechanisms involved in GMP biosynthesis by this strain. Typical chemical changes in XMP fermentation showed that the maximal amount of the product was approximately 2.75 mg per ml of medium.
Effects of airway luminal concentration of albumin on histamine‐induced mucosal exudation of radio‐iodine labelled albumin (1991)

In an in vivo study of guinea-pig airway barriers we have examined the effects of the luminal concentration of albumin on exudation (outward) and absorption (inward) permeabilities to radio-iodine labelled albumin. Previously validated techniques for superfusion of solutes onto the tracheobronchial mucosal surface and for subsequent tracheal lavage were employed. [125I]albumin was administered intravenously as plasma tracer and [131I]albumin was superfused topically as absorption tracer. Histamine (5.0 nmol) was superfused onto the mucosal surface together with the absorption tracer and in the presence of different albumin concentrations (0.3, 3.0 and 30 mg ml-1). The experiment was terminated 10 minutes after the tracheal mucosal superfusion and samples of plasma and tracheal lavage fluid were collected. The mucosal exudation response was calculated from the detection of [125I]albumin in the airway lumen. The absorption ability of the mucosa was determined by the detection of [131I]albumin in circulating plasma. Histamine induced a significant mucosal exudation of [125I]albumin. This effect was unaffected by the level of albumin on the mucosal surface. There was a small but significant absorption of [131I]albumin in the presence of 0.3 and 3.0 mg ml-1 of albumin in the luminal liquid. An albumin concentration of 30 mg ml-1 markedly increased the rate of absorption of [131I]albumin. However, the absorption rate was not affected by the histamine-induced mucosal exudation process at any level of luminal albumin. The present data further demonstrates that plasma exudation and mucosal absorption are independent processes. The data are in keeping with the view that an increased subepithelial hydrostatic pressure moves the plasma exudate across the mucosa as a distinct outward process.
An <i>ab initio</i> cluster study of the structure of the Si(001) surface (2000)

Ab initio calculations, employing double zeta plus polarization (DZP) basis sets and generalized valence bond (GVB) wave functions, have been performed on clusters of varying size, to investigate the utility of such clusters as prototypes for the study of silicon surfaces, and to investigate the effect of the level of theory used on predicted results. This work builds on landmark papers by Goddard in 1982 and Paulus in 1998 that demonstrate that a single reference wave function description of the silicon dimer bond is incorrect, and that a multireference description results in a symmetric dimer in a silicon cluster containing one dimer. In this work, it is shown that the imposition of arbitrary geometrical constraints (fixing subsurface atoms at lattice positions) on cluster models of the Si(100) surface can also lead to nonphysical results. Calculations on the largest clusters, without geometrical constraints, reveal that surface rearrangement due to dimer bond formation is “felt” several layers into the bulk. The predicted subsurface displacements compare favorably to experiment. Thus, small clusters, such as Si9H12, cannot adequately represent bulk behavior. Vibrational analysis shows that dimer buckling modes require minimal excitation energy, so the experimental observation of buckled dimers on silicon surfaces may reflect the ease with which a symmetric dimer can be perturbed from its minimum energy structure. In the study of surface reconstruction and relaxation, and the associated issue of the buckling of dimer surfaces, it is critical to use adequate wave functions. As shown in this work and previously by Goddard and Paulus, this generally means that multireference treatments are needed to correctly treat the dangling bonds.
Development of Hemagglutination Assays (1977)

Studies were undertaken to enhance the sensitivity of a previously developed RPHA test for HBsAg. A net increase in sensitivity of approximately 3-fold was achieved by modifying the elution procedure used to purify chimpanzee anti-HBs by affinity chromatography. A further 3- or 4-fold sensitivity increase was achieved by increasing the volume of specimen tested. A concomitant increase in nonspecific agglutination usually observed with increased specimen size was avoided by incubating the reaction mixture at 37 or 45 degrees C. Evaluation of the test in detection of HBsAg in blood obtained from volunteer donors indicates that the materials produced at the New York Blood Center using the modified test protocol compare favorably with a commercial RPHA test. Modifications which did not contribute toward enhancing sensitivity are also reported.
Power system restoration incorporating interactive graphics and optimization (2002)

A new power system restoration planning methodology which incorporates interactive graphics and an optimization algorithm is presented. The interactive graphics provides a tool to define restoration scenarios, view the restoration process, and display the optimization and simulation results. By introducing the concept of optimal restoration scenario, the process of selecting the control variables can be formulated as a mathematical problem which can be solved by nonlinear programming. This approach removes most of the guesswork found in conventional restoration planning and provides a systematic and optimal solution in the sense of minimizing the variations from normal, and the number of control variable adjustments from stage to stage. The optimization reduces the duration of the restoration procedure and guarantees the security of all variables during the restoration process by respecting all steady-state operating constraints.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
PP.17.19 (2015)

Objective: Evidence is available that increased 24 h blood pressure (BP) variability (V) contributes to organ damage and cardiovascular events rate in hypertension, independently from BP levels. Limited information is available however on the effects of different monotherapies and of drug combinations on 24 h BPV. Aim of this work was to explore the effects on 24 h BP mean values and on BPV of monotherapies with a calcium antagonist (Lercanidipine, L) or an ACE inhibitor (Enalapril, E), and of their combination. Design and method: 67 hypertensives (age 60–85yrs) received 4-week treatments with L (10 mg), E (20 mg), their combination (L10+E20) or placebo (P) in a randomized order. 24 h ambulatory BP recordings were performed at the end of each treatment. 24 h average systolic (S) and diastolic (D)BP levels were computed, and BPV was quantified as 24 h weighted standard deviation (SDw) and as average real variability (ARV) for SBP and DBP. The dependence of changes in BPV on changes in average BP was tested by linear regression analysis. Results: When comparing monotherapies, E produced a larger decrease in average 24 h SBP and DBP than L, the largest reduction being induced by L+E. 24 h short term BPV was best reduced by L+E, especially for DBPV. L induced a larger decrease in 24 h DBPV than E, the effect being more evident for ARV (table). No significant correlation was found between the reduction in average mean BP levels and the concomitant reduction in 24 h BP standard deviation for all treatments (R2 always <0.09,p = NS).Conclusions: L+E combination reduced average 24 h SBP and DBP more effectively than the respective monotherapies, with E being slightly more effective than L in reducing BP levels. Short term SBPV was significantly reduced only by L+E in particular when assessed as AVR. The reduction in short term DBPV was more pronounced, independent from the reduction in average BP levels, maximal with combination treatment and more evident with L than with E. These results may have implications for cardiovascular protection when selecting antihypertensive drugs in elderly hypertensive patients, and further support the efficacy of calcium channel blockers in reducing BPV.
ChemInform Abstract: Case Histories of Peptidomimetics: Progression from Peptides to Drugs (1994)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Hydrophobic coatings for MEMS applications (2008)

Different kinds of thin-film coatings were investigated with regard to their applicability as hydrophobic coatings for MEMS. The films were deposited onto silicon and borosilicate glass substrates by spincoating of Dyneon™ PTFE and PFA, plasmapolymerization of HMDS-N and C4F8 as well as liquid-phase and vapor-phase coating of SAMs from DDMS, FDTS, FOTS and Geleste Aquaphobe™ CM. The layer properties were analyzed using profilometry, FTIR, SEM and contact angle measurements. Furthermore, the adhesion of the layers to the substrates was determined in an acetone ultrasonic bath. The influence of various deposition process parameters on the properties of the films was investigated. As these layers can be used in microfluidic systems, as water-repellent layers and as anti-stiction coatings, they are suited for versatile fields of application.