gebhart/patrepeval huggingface dataset:
Effects of Rumensin® and Tylan® in Finishing Diets with Wet Distillers Grains Plus Solubles (2009)

A total of 3,632 crossbred steers at three different sites (Nebraska, Colorado and Oklahoma) were utilized in a randomized complete block design (RCBD) study. Data were combined for the Colorado and Oklahoma trials. Steers were fed one of five treatments: 1) Traditional corn diet with Rumensin and Tylan (CORN+RT); 2) Wet distillers grains plus solubles (WDGS); 3) WDGS with Rumensin (WDGS+R); 4) WDGS with Rumensin and Tylan (WDGS+RT); and 5) WDGS with expanded dose range of Rumensin (44.4 g/ton) and Tylan (WDGS+HIRT) to evaluate the effects of Rumensin and Tylan in feedlot diets containing WDGS. In WDGS diets, feed-to-gain ratio (F:G) was improved when Rumensin and Tylan were included (P < 0.05). With the exception of dressing percentage, there were no differences in performance or carcass characteristics when Rumensin was fed at 33.3 g/ton compared to 44.4 g/ton. Treatments containing Tylan resulted in significantly fewer liver abscesses than other treatments. Cattle fed Rumensin and Tylan diets containing WDGS had improved F:G and decreased liver abscesses compared to those receiving diets with no additives, regardless of corn processing method.
Olefinic nitrone and nitrile oxide [3 + 2] cycloadditions. A short stereospecific synthesis of biotin from cycloheptene (1980)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTOlefinic nitrone and nitrile oxide [3 + 2] cycloadditions. A short stereospecific synthesis of biotin from cycloheptenePat N. Confalone, Giacomo Pizzolato, Dianne Lollar-Confalone, and Milan R. UskokovicCite this: J. Am. Chem. Soc. 1980, 102, 6, 1954–1960Publication Date (Print):March 1, 1980Publication History Published online1 May 2002Published inissue 1 March 1980https://pubs.acs.org/doi/10.1021/ja00526a033https://doi.org/10.1021/ja00526a033research-articleACS PublicationsRequest reuse permissionsArticle Views1357Altmetric-Citations62LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Integration of tomographic SAR inversion and PSI for operational use (2012)

Persistent Scatterer Interferometry (PSI) is a special case of tomographic SAR Inversion and has advantages of 1) computational efficiency and 2) direct access to the phase histories independent of the motion models. However, it is restricted to single scatterers. Tomographic SAR inversion, on the other hand, delivers more information such as the number of scatterers, topography and motion information of layover areas. However, it is computationally more expensive, especially when high elevation resolution is required. For practical data processing, the combination of the efficiency of PSI and the information gain of tomographic SAR could be very helpful. In this paper, we address the integration of tomographic SAR inversion and PSI for operational use.
A large retrospective analysis of CDK 4/6 inhibitor retreatment in ER+ metastatic breast cancer (MBC). (2019)

1053 Background: Sequential retreatment with endocrine therapy (ET) has been the clinical paradigm for ER+ MBC due to persistent dependence on hormone signaling. Recently CDK4/6i + ET have improved PFS and are routinely utilized in the first/second- line setting. Whether this paradigm of sequential retreatment holds for CDK 4/6i is unknown. To evaluate the potential benefit of CDK4/6i re-treatment we conducted this retrospective analysis. Methods: We identified ER+/HER2- MBC pts treated with ≥ 2 lines of CDK4/6i at our institution between 2015-2018. We categorized pts based on reason for discontinuation of their first CDK4/6i: cohort 1 – switch to alternate CDK4/6i due to toxicity; cohort 2 – retreatment with same CDK4/6i beyond progression with change of ET and cohort 3- switch to alternate CDK4/6i as monotherapy or with same or another ET. We analyzed pt demographics, imaging reports and time to subsequent therapy (TTST) for every CDK4/6i line for each cohort. If a pt received > 2 lines of CDK4/6i, then that pt was evaluated for every CDK4/6i exposure. Results: 135 pts received ≥ 2 lines of CDK4/6i treatment (Tx). Cohorts 1, 2 and 3 had 23, 43 pts and 84 pts respectively. In Cohort 2, 95% of pts received 2 subsequent CDK 4/6i + ET Tx; 56% had the second CDK4/6i in second-line met setting. TTST1 (1st CDK4/6i Tx) was 9.6m (95% CI 4.9 - 11 m), TTST2 (second CDK4/6i Tx) was 4.5m (95% CI 3.3 – 7.6 m) and 35% had TTST2 ≥ 24 weeks. For Cohort 3, 48% were retreated with a different CDK 4/6i in ≥ fifth-line. 51% received 2 subsequent CDK 4/6i Tx with 18% in second-line met setting. TTST1 was 9.6 m (95% CI 5.9 – 12 m), TTST2 was 4.4 m (95% CI 3.8 – 5.9 m) and 29% had TTST2 ≥ 24 weeks. In cohort 3, 29% (n=24) pts had PD as best response at the time of first CDK4/6i exposure but 29% (7/24) achieved a radiologic response to their second CDK4/6i Tx. Pts had tumor sequencing using MSK-IMPACT which will be correlated with TTST. Conclusions: This large single institution retrospective analysis suggests that retreatment with a CDK4/6i regimen should be evaluated in prospective trials. Additionally, despite PD as best response with the first CDK4/6i (palbociclib/ribociclib) regimen, a subset of pts had radiologic response to a subsequent abemaciclib-containing regimen, which is an hypothesis generating observation.
Hybrid system, a new low cost parallel cluster (2003)

This paper describes a new parallel architectural system which we called Hybrid System. As the name implies, Hybrid System is a combination of both SIMD and MIMD systems working concurrently. This new parallel architecture has the capability of achieving speed-up rates more than MIMD can achieve alone and can also be more flexible than multiple SIMD on a single station. In this paper, we introduce our new SIMD concept and also show the contribution of the SIMD on the Hybrid System. We also developed a general formula for determining the speedup of the Hybrid System so that accurate predictions can be made on its performance. This, we establish by comparing the measured speedup with the computed speedup for a volume rendering application.
Mouse Testicular and Sperm Cell Development Characterized from Birth to Adulthood by Dual Parameter Flow Cytometry1 (1986)

Dual parameter flow cytometry was used to investigate cellular changes in male germinal tissue during normal postpartum maturation in B6C3F1/J mice. Animals were killed at 2-day intervals from 2 to 42 days postpartum and at 48, 64, 72, 93 and 100 days postpartum. Testicular, cauda epididymis and vas deferens cell suspensions were stained with the metachromatic fluorochrome acridine orange and measured by flow cytometry for red and green fluorescence levels after excitation by blue laser light. Intensities of red and green fluorescence reflect amounts of single- and double-strand nucleic acid sites available for acridine orange staining, respectively, and were used to classify cells on the basis of ploidy level, RNA content, and chromatin structure, as defined by susceptibility to acid denaturation of DNA in situ. Sperm from cauda epididymis and vas deferens were examined by light microscopy to determine frequency of abnormal sperm head morphology. Fluorescence data derived from acridine orange-stained testicular cells quantified the sequential changes in 1) proportions of haploid, diploid and tetraploid cell types during the first round of spermatogenesis, and 2) proportions of round, elongating, and elongated spermatids during the first round of spermiogenesis. Ratios of the three major testicular populations (haploid, diploid, and tetraploid) reached adult levels by 48 days postpartum. Sperm cells were first detected in the cauda epididymis and vas deferens on 30 and 36 days postpartum, respectively. Early sperm populations, compared to adult sperm, exhibited up to 89% abnormalities in sperm head morphology that correlated with significant levels of abnormal chromatin structure. Percentage of sperm head abnormalities and chromatin structure in the cauda epididymis and vas deferens approached normal adult levels by 42 and 48 days postpartum, respectively.
Prestack waveform inversion of multi‐component seismic data (2000)

PreviousNext No AccessSEG Technical Program Expanded Abstracts 2000Prestack waveform inversion of multi‐component seismic dataAuthors: Subhashis MallickSubhashis MallickWestern Geophysical Company, Houston, Texashttps://doi.org/10.1190/1.1815910 SectionsAboutPDF/ePub ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinked InReddit Permalink: https://doi.org/10.1190/1.1815910FiguresReferencesRelatedDetailsCited byData-driven prestack-waveform inversion using genetic algorithm: Methodology and examplesLingxiao Jia, Subhashis Mallick, and Cheng Wang7 September 2021 | Interpretation, Vol. 9, No. 4Inversion of wide-azimuth multicomponent vertical seismic profile data for anisotropic subsurface propertiesTao Li, Subhashis Mallick, Naser Tamimi, and Thomas Davis1 September 2016Full-Waveform Inversion I Complete Session1 September 2016Technical Program in full - Part I (ACQ 1 - PS P1)1 September 2016References24 May 2016Amplitude-variation-with-offset and prestack-waveform inversion: A direct comparison using a real data example from the Rock Springs Uplift, Wyoming, USASubhashis Mallick and Samar Adhikari27 February 2015 | GEOPHYSICS, Vol. 80, No. 2Prestack waveform inversion of three-component, two-azimuth surface seismic data for azimuthally dependent anisotropic parameters using a parallelized nondominated sorting genetic algorithmTao Li* and Subhashis Mallick5 August 2014Amplitude-variation-with-offset and prestack waveform inversion- a direct comparison using a real data exampleSubhashis Mallick*, Samar Adhikari, and Josiane Pafeng5 August 2014Accurate estimation of density from the inversion of multicomponent prestack seismic waveform data using a nondominated sorting genetic algorithmAmit Padhi and Subhashis Mallick31 December 2012 | The Leading Edge, Vol. 32, No. 1Multicomponent prestack waveform inversion for isotropic elastic media parameters using a non-dominated sorting genetic algorithmAmit Padhi and Subhashis Mallick25 October 2012Multicomponent prestack waveform inversion for VTI media parameters using a non-dominated sorting genetic algorithmAmit Padhi and Subhashis Mallick25 October 2012Extending the high end of C‐wave bandwidth to match P‐wavelengthsJames Gaiser, Richard Verm, and Alvaro Chaveste8 August 2011Prestack Waveform Inversion‐ the present state and the road aheadSubhashis Mallick, Pradip Kumar Mukhopadhyay, Amit Padhi, and Vladimir Alvarado21 October 2010 SEG Technical Program Expanded Abstracts 2000 ISSN (print):1052-3812 ISSN (online):1949-4645 Copyright: 2000 Pages: 2484 publication data© 2000 Copyright © 2000 Society of Exploration GeophysicistsPublisher:Society of Exploration Geophysicists HistoryPublished Online: 04 Jan 2005 CITATION INFORMATION Subhashis Mallick, (2000), "Prestack waveform inversion of multi‐component seismic data," SEG Technical Program Expanded Abstracts : 2273-2276. https://doi.org/10.1190/1.1815910 Plain-Language Summary PDF DownloadLoading ...
X-band microstrip array antenna in suspended technology (2002)

Future spaceborne synthetic aperture radar (SAR) instruments for high resolution mapping of the Earth will require dual polarised phased array antennas with large frequency bandwidths and high efficiencies. A novel type of dual polarized microstrip array antenna has been developed for C or X band SAR application. The radiating element is made of two perpendicular grids which gives a reduced surface area and good port to port and cross-polarisation isolation. An array of these elements working at X-band has been manufactured in flight representative suspended technology. The technology is based on thin dielectric layers suspended in air which reduces losses and surface wave coupling.
Identification of a Major Heparin-binding Site in Kallistatin (2001)

Kallistatin is a heparin-binding serine proteinase inhibitor (serpin), which specifically inhibits human tissue kallikrein by forming a covalent complex. The inhibitory activity of kallistatin is blocked upon its binding to heparin. In this study we attempted to locate the heparin-binding site of kallistatin using synthetic peptides derived from its surface regions and by site-directed mutagenesis of basic residues in these surface regions. Two synthetic peptides, containing clusters of positive-charged residues, one derived from the F helix and the other from the region encompassing the H helix and C2 sheet of kallistatin, were used to assess their heparin binding activity. Competition assay analysis showed that the peptide derived from the H helix and C2 sheet displayed higher and specific heparin binding activity. The basic residues in both regions were substituted to generate three kallistatin double mutants K187A/K188A (mutations in the F helix) and K307A/R308A and K312A/K313A (mutations in the region between the H helix and C2 sheet), using a kallistatin P1Arg variant as a scaffold. Analysis of these mutants by heparin-affinity chromatography showed that the heparin binding capacity of the variant K187A/K188A was not altered, whereas the binding capacity of K307A/R308A and K312A/K313A mutants was markedly reduced. Titration analysis with heparin showed that the K312A/K313A mutant has the highest dissociation constant. Like kallistatin, the binding activity of K187A/K188A to tissue kallikrein was blocked by heparin, whereas K307A/R308A and K312A/K313A retained significant binding and inhibitory activities in the presence of heparin. These results indicate that the basic residues, particularly Lys(312)-Lys(313), in the region between the H helix and C2 sheet of kallistatin, comprise a major heparin-binding site responsible for its heparin-suppressed tissue kallikrein binding.
Adjuvant and mitogenic properties of a supernatant fraction of sonically treated Myobacterium bovis (BCG) (1976)

A water-soluble, oil-free supernatant fraction of sonically treated BCG (BCG-SS) was shown to be an immunological adjuvant and a mitogen. When BCG-SS and sheep erythrocytes (SRBC) were injected intravenously into mice, the plaque-forming cell (PFC) response was 10 times greater than that induced by injection of SRBC alone. Circulating antibody responses to SRBC and to bovine serum albumin were also enhanced by BCG-SS. The in vitro enhancement of PFC and circulating antibody responses did not require mineral oil or exogenous lipids. In vitro PFC responses by normal mouse spleen cells were also greatly increased in the presence of BCG-SS. Anti-theta serum-treated spleen cells from mice that had been lethally irradiated and reconstituted with normal bone marrow cells also gave a higher PFC response to SRBC in the presence of BCG-SS. This suggests that BCG-SS can stimulate B lymphocytes to develop an immune response when T lymphocytes are severely depleted or absent. BCG-SS also stimulated the uptake of 125IUdR by normal spleen cell cultures, indicating that it is a mitogen.
213 Radiomic Machine Learning Algorithms Discriminate Pseudo-Progression From True Progression in Glioblastoma Patients (2018)

Zinn, Pascal O MD, PhD; Abrol, Srishti; Kotrotsou, Aikaterini; Hassan, Ahmed; Elshafeey, Nabil; Idris, Tagwa; Manohar, Naveen; Hassan, Islam; Salek, Kamel; Farid, Nikdokht; McDonald, Carrie; Weathers, Shiao-Pei; Bahrami, Naeim; Bergamaschi, Samuel; Elakkad, Ahmed; Alfaro-Munoz, Kristin; Moron, Fanny; Huse, Jason MD; Weinberg, Jeffrey S MD; Ferguson, Sherise D MD; Kogias, Evangelos; Heimberger, Amy B MD; Sawaya, Raymond MD; Kumar, Ashok M; de Groot, John; Law, Meng; Colen, Rivka R MD Author Information
[Surgery of juvenile chronic arthritis]. (1991)

A number of surgical procedures can be proposed in juvenile chronic arthritis (JCA). These are particularly useful in two circumstances: 1), during the early stages of the disease, as local treatment for hyperplasic synovium (intra-articular injection or synovectomy) in order to avoid further articular destruction; 2) in the late stages of the disease with the aim of restoring function to as near normal as possible (osteotomy, arthrodesis, arthroplasty, tendon repair). However, in all circumstances, such surgery must be decided upon by a team consisting of paediatrician and orthopaedic surgeon. Procedures are often multiple and require careful preparation including psychological support, nutritional, medical and orthopaedic care. And should be followed by intensive and specific physiotherapy. When these conditions are fulfilled, the operative procedures may restore nearly normal joint function in severe forms of JCA, thus allowing children and adolescents to maintain good physical, intellectual and psychological development through independent mobility.
CDC Orion kabuli chickpea (2011)

Taran, B., Bandara, M., Warkentin, T., Banniza, S. and Vandenberg, A. 2011. CDC Orion kabuli chickpea. Can. J. Plant Sci. 91: 355–356. CDC Orion, a kabuli chickpea (Cicer arietinum L.) cultivar, was released in 2010 by the Crop Development Centre, University of Saskatchewan for distribution to Select seed growers in western Canada through the Variety Release Program of the Saskatchewan Pulse Growers. CDC Orion has a pinnate leaf type, fair resistance to ascochyta blight (Ascochyta rabiei Pass. Lab.), late maturity, large seed size and high yield potential in the Brown and Dark Brown soil zones of the Canadian prairies.
Intervención educativa para la prevención de embarazos no deseados y enfermedades de transmisión sexual en adolescentes de la ciudad de Toledo (2005)

Following the intervention, an improvement has been noted in the degree of knowledge related to birth control methods and AIDS transmission and a more positive attitude regarding HIV.
Current viral risks of blood and blood products (2000)

A number of viruses may be transmitted by blood transfusion, the most important of these are HIV, human T-cell lymphotrophic retrovirus (HTLV), hepatitis B virus (HBV), and hepatitis C virus (HCV). A series of overlapping safety measures are in place and are being improved and supplemented continuously. As a result, the risk of transmission of these viruses in the USA has been reduced to between one and four per million blood components transfused.
Structural characterization of a linear [Au.cntdot..cntdot..cntdot.Pt.cntdot..cntdot..cntdot.Au] complex, Au2Pt(CH2P(S)Ph2)4, and its oxidized linear metal-metal bonded [Au-Pt-Au] product, Au2Pt(CH2P(S)Ph2)4Cl2 (1987)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTStructural characterization of a linear [Au.cntdot..cntdot..cntdot.Pt.cntdot..cntdot..cntdot.Au] complex, Au2Pt(CH2P(S)Ph2)4, and its oxidized linear metal-metal bonded [Au-Pt-Au] product, Au2Pt(CH2P(S)Ph2)4Cl2H. H. Murray, David A. Briggs, Guillermo. Garzon, Raphael G. Raptis, Leigh C. Porter, and John P. FacklerCite this: Organometallics 1987, 6, 9, 1992–1995Publication Date (Print):September 1, 1987Publication History Published online1 May 2002Published inissue 1 September 1987https://doi.org/10.1021/om00152a030Request reuse permissionsArticle Views148Altmetric-Citations41LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (551 KB) Get e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
Crystal Structures of Neuraminidase-Antibody Complexes (1989)

The nature of antigen-antibody interactions has become clearer in the last few years as crystal structures of antigen-antibody complexes have been elucidated. Such structures have permitted a visualization of the interface between antigen and antibody. Three-dimensional structures of five complexes have now been reported, two containing the influenza virus neuraminidase as antigen and the Fabs NC41 and NC10 (Colman et al. 1987, 1989), and three with hen egg-white lysozyme and the Fabs D1.3, HyHEL-5, and HyHEL-10 (Amit et al. 1986; Sheriff et al. 1987b; E.A. Padlan et al., in prep.). The major parameters that define the scope of the antigen-antibody interface are emerging as more structures are solved and refined to greater precision. Several reviews have dealt with this topic (Mariuzza et al. 1987; Colman 1988; Davies et al. 1988).
X-ray atomic orbital analysis of 4<i>f</i> and 5<i>d</i> electron configuration of SmB<sub>6</sub> at 100, 165, 230 and 298 K (2010)

Accurate electron-density measurement of SmB(6) at 100, 165, 230 and 298 K, and X-ray atomic orbital (XAO) analysis were carried out. The 4f-electron density around Sm and 5d electron density at approximately 1 A from Sm were analysed by XAO analysis. The 5d electron density is due to the electrons of the 5d(J = 5/2)Gamma(8) orbitals which stem from the e(g) orbitals in the strong field approximation. The change in electron populations of the 5d(5/2)Gamma(8) orbitals with temperature is similar to that of the resistivity. Since the conduction band consists of 5d(5/2)Gamma(8) and B-2p orbitals according to band theory, this indicates that the larger populations of the 5d(5/2)Gamma(8) orbitals correspond to the larger number of localized electrons and are correlated to the resistivity of SmB(6). The occupation of the bulky 5d(5/2)Gamma(8) orbitals may be the reason for the elongation of the lattice parameter below 150 K. The 4f(7/2)Gamma(6) orbitals are obviously occupied except at 100 K, which seems to be caused by the energy gap between 4f(5/2) and 4f(7/2) states, which begins to exist between 100 and 150 K, and may represent one of the properties of a Kondo insulator.