gebhart/patrepeval huggingface dataset:
Highly Sensitive Surface Enhanced Raman Scattering Substrates Based on Filter Paper Loaded with Plasmonic Nanostructures (2011)

We report a novel surface enhanced Raman scattering (SERS) substrate platform based on a common filter paper adsorbed with plasmonic nanostructures that overcomes many of the challenges associated with existing SERS substrates. The paper-based design results in a substrate that combines all of the advantages of conventional rigid and planar SERS substrates in a dynamic flexible scaffolding format. In this paper, we discuss the fabrication, physical characterization, and SERS activity of our novel substrates using nonresonant analytes. The SERS substrate was found to be highly sensitive, robust, and amiable to several different environments and target analytes. It is also cost-efficient and demonstrates high sample collection efficiency and does not require complex fabrication methodologies. The paper substrate has high sensitivity (0.5 nM trans-1,2-bis(4-pyridyl)ethene (BPE)) and excellent reproducibility (~15% relative standard deviation (RSD)). The paper substrates demonstrated here establish a novel platform for integrating SERS with already existing analytical techniques such as chromatography and microfluidics, imparting chemical specificity to these techniques.
System based on abstract prototyping and motion capture to support car interior design (2015)

Computer-Aided Design and Applications is an international journal on the applications of CAD and CAM. It publishes papers in the general domain of CAD plus in emerging fields like bio-CAD, nano-CAD, soft-CAD, garment-CAD, PLM, PDM, CAD data mining, CAD and the internet, CAD education, genetic algorithms and CAD engines. The journal is aimed at all developers and users of CAD technology to ptovide CAD solutions for various stages of design and manufacturing. The journal publishes all about Computer-Aided Design and Computer-Aided technologies.
HeartSaver VAD: A Totally Implantable Ventricular Assist Device. Results of In Vivo Studies (2000)

Currently, the most widely utilized ventricular assist devices (VADs) require percutaneous connections and are located either externally (e.g., Thoratec, Abiomed) or intra-abdominally (e.g., Novacor, TCI). These attributes have been implicated in a variety of complications (infection, thromboembolic, gastrointestinal, etc.). To address these concerns, a totally implantable VAD that requires no percutaneous connections and can be implanted in the left hemi-thorax has been developed. The developed device has undergone in vivo evaluation as part of the design and development process. A total of 43 implants in the bovine model, with 5 device versions, have been conducted between July 1992 and February 2000. These studies successfully have demonstrated several important aspects of the developed device, including 1) feasibility of a totally implantable system; 2) capability of the device to support a dysfunctional heart; and 3) ability of the device to provide flows up to 10 L/min in a physiological setting. The studies to date have played a vital role in the design and development process as well as demonstrating the feasibility of a totally implantable intrathoracic VAD. Based on these studies, design optimization was conducted, resulting in the development of the pre-clinical version of the device in preparation for clinical trials.
Biology and culture of the clown loach<i>Chromobotia macracanthus</i>(Cypriniformes, Cobitidae) : 2- Importance of water movement and temperature during egg incubation (2012)

International audience
A Pilot Study (SWOG S0429) of Weekly Cetuximab and Chest Radiotherapy for Poor-Risk Stage III Non-Small Cell Lung Cancer (2013)

Concurrent weekly cetuximab/chest RT followed by maintenance cetuximab for poor-risk stage III NSCLC was well tolerated. Further studies with larger sample sizes will be useful to establish the optimal therapeutic ratio of this regimen.
ChemInform Abstract: Intramolecular Cyclopropanation of 7‐Diazotethered‐1,3,5‐cycloheptatriene: Preparation and Reactions of Tricyclo[5.3.0.0<sup>2,10</sup>]deca‐3,5‐dien‐9‐one. (1998)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
A 100 nm copper/low-k bulk CMOS technology with multi Vt and multi gate oxide integrated transistors for low standby power, high performance and RF/analog system on chip applications (2003)

We report a 100 nm modular bulk CMOS technology platform with multi Vt and multi gate oxide integrated transistors that enables device and circuit co-design (M. Fukuma et al., VLSI Tech., 2000) techniques (e.g. well biasing and power down/reduction) for low standby power (LSP), high performance (HP), high speed (HS), and RF/analog system on chip (SoC) applications. The transistor performances are comparable to or better than recently reported data at the 100 nm technology node. This technology also features an all-layer copper/low-k (<3.0) interlayer dielectric (ILD) backend for speed improvement and dynamic power reduction (S. Parihar et al., Proc. IEDM, 2001).
Immunotherapy response evaluation with magnetic resonance elastography (MRE) in advanced HCC (2019)

Our pilot MRE data suggests early change in tumor stiffness may be an indicator of immunotherapy response in patients with advanced HCC.
Oleamide‐mediated sleep induction does not depend on perturbation of membrane homeoviscosity (1999)

To verify whether the sleep-inducing properties of oleamide were related to its ability to perturb membrane homeoviscosity, affecting 5-HT(2A) receptors, we compared the effects of oleamide and oleic acid, the latter lacking both the sleep-inducing effect and the action on 5-HT(2A) receptors. In binding studies the two compounds did not directly interact with rat brain cortex 5-HT(2A) receptors, nor did they increase the affinity of a 5-HT(2A) agonist, either in vitro or ex vivo. They had similar fluidizing effects, in vitro at high concentrations (>/=10 microM), and ex vivo after a dose of 100 mg/kg, and they reduced locomotor activity with similar potency. There thus appears to be no causal relationship between the fluidizing effects of oleamide and its sleep-inducing properties.
Self-Reproduction of Micelles and Liposomes and the Transition to Life (1993)

Micelles and vesicles (liposomes) are examples of geometrically bounded molecular structures. Conditions have been found under which micelles can be brought to self-reproduction by a simple chemical reaction which takes place at the boundary of the micellar system, at the interface between the micelles' interior and the exterior bulk solvent. During this reaction, the molecules of the boundary are produced which leads to the formation of more micelles as time progresses. The examples are micelles and reverse micelles build by octanoate molecules, and the reactions which lead to self-reproduction are ester hydrolysis or alcohol oxidations.In another approach, the reproducing micelles are first created chemically by a simple hydrolysis reaction in a two-phase system made of an alkaline aqueous phase and an organic fatty acid ester phase. In an extension of this concept, as upper organic phase octanoic anhydride was used. The initial conditions of the alkaline aqueous phase were so that the pH drop during the reaction led to the formation of vesicles which were able to take up anhydride molecules and to act as a catalyst for the hydrolysis of the remaining anhydride molecules.The investigation of fatty acid micelles and vesicles is related to the possible role of bounded molecular structures during the early prebiotic evolution on Earth. Because self-reproducing micelles and vesicles can be considered as examples for the chemical version of an autopoietic unit, the requirements of the minimal and universal definition of the living are fulfilled. (According to the definition by Maturana and Varela, an autopoietic unit is a structure which is self-generating and self-perpetuating as a consequence of its own activities within a boundary of its own making).
Highly Sensitive Waveguide Bragg Grating Temperature Sensor Using Hybrid Polymers (2016)

A waveguide Bragg grating temperature sensor implemented using a hybrid inorganic-organic material (Ormocer) with a 25-times higher temperature sensitivity than a typical silica fiber is presented. The sensor consists of second order gratings (1010-nm pitch) in 5 μm × 5 μm waveguides fabricated on a planar substrate using the replication-based methods. The gratings were imprinted in the under-cladding layer, and the waveguide cores were patterned on top by capillary filling of microchannels, which were defined in a transparent and flexible mold. The somewhat larger, slightly multimode waveguides facilitate pigtailing with an optical fiber but lead to three reflection peaks corresponding to the different excited waveguide modes. The peak at the longest wavelength (Bragg wavelength at 1539 nm, corresponding to the fundamental mode) was tracked during temperature testing, and a sensitivity of -249 pm °C <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">-1</sup> was found.
ChemInform Abstract: Regioselective Allylation and Propargylation Using Acylsilanes. Facile Synthesis of PGE3 and F3α Methyl Ester. (1992)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Postnatal change of glycinergic IPSC decay in sympathetic preganglionic neurons (1994)

The characteristics of glycinergic inhibitory postsynaptic currents (IPSCs) in sympathetic preganglionic neurons (SPNs) of neonatal rats were studied by whole-cell recordings in transverse spinal cord slices. In relation to postnatal age, the decay time constants of these currents decreased without a comparable effect on their rise time. This may result from alpha-subunit switching of the glycine receptor and/or increased glycine uptake during this period of postnatal life. The kinetics of glycinergic IPSCs were also temperature- and voltage-dependent. Whereas, compared with room temperature, rise and decay of the events were faster at more physiological temperature, only the decay increased upon depolarization. Visual identification of SPNs was confirmed by intracellular staining and comparison with retrogradely labeled SPNs.
204 Intelligent Lighting System using Infrared Communication (2006)

In recent years, various types of equipment have become more intelligent. In this research, we propose an intelligent lighting system using infrared communication technology for direct communication between lighting fixtures and illuminance sensors in order to provide the necessary illuminance to a desired location. We actually constructed an experiment simulator based on this concept and verified the effectiveness of the newly developed control method. Verification tests were conducted using an optimization algorithm specialized for lighting control, and the results showed that the various illuminance sensors converged to the preset target illuminance in a very short time. We also confirmed that the system can respond adaptively to the movement of illuminance sensors.
Investigating excited state dynamics in bacteriorhodopsin by impulsive stimulated emission pumping. (2002)

Femtosecond stimulated emission pumping experiments from bacteriorhodopsins fluorescent state show for the first time that it is a photocycle intermediate, with a constant nonisomerized structure throughout its 0.5 psec lifetime. Implications concerning internal conversion dynamics are discussed.
Report on the first "XQuery Implementation, Experience and Perspectives" workshop (XIME-P) (2004)

The XQuery Implementation, Experience and Perspectives (XIME-P) workshop was organized by Ioana Manolescu and Yannis Papakonstantinou in cooperation with the ACM SIGMOD Conference, and was held in Maison de la Chimie, in Paris, France, on June 17 and 18, 2004. This report summarizes the goals and topics of the workshop, presents the major workshop highlights and the main issues discussed during the workshop.
Pharmacokinetics of Intravenous Immunoglobulin (Gammagard) in Bone Marrow Transplant Patients (1991)

The pharmacokinetics of an intravenous immunoglobulin (IVIG), Gammagard (Baxter Healthcare Corp., Glendale, CA), were measured in 31 cytomegalovirus (CMV) antibody negative bone marrow transplant (BMT) patients as part of a multicenter efficacy trial of 2 weekly dose regimens. Since all patients lacked antibody to CMV and received only screened CMV negative blood products, the half-life of the exogenous CMV antibody could be measured with an ELISA assay. The CMV antibody titer was related to the immunoglobulin concentration using a standard curve. Compared with the 22-day half-life in normal subjects, the half-life in BMT patients was approximately 6 days for either the 250 mg/kg or 500 mg/kg dose regimen. The half-life did not change over the subsequent 3 weekly doses. Peak concentrations were 3.5 +/- 1.4 and 2.6 +/- 0.7 mg/mL of IVIG in week 1 as well as 5.5 +/- 2.6 and 3.4 +/- 1.2 mg/mL in week 3 after the 250 mg/kg and 500 mg/kg, respectively. Total body clearance of IVIG was 0.61 and 0.46 mL/kg/hr for the 500 mg/kg and 250 mg/kg, respectively.
Economic evaluation of alternative ethanol fermentation processes (1984)

Eleven alternative fermentation schemes for ethanol production are compared. Conventional batch, continuous, cell recycle, and immobilized cell processes, as well as membrane, extraction, and vacuum processes which remove ethanol from the broth selectively as it is produced, are considered. The processes are compared on identical bases using a consistent model for the yeast metabolism. Both molasses and cellulose hydrolyzate are considered as feeds. Optimized ethanol plants, including feed preparation, fermentation, and product recovery sections are designed and total costs are projected.
Esophageal radioprotection by swallowed JP4-039/F15 in thoracic-irradiated mice with transgenic lung tumors. (2015)

Intraesophageal radioprotective small-molecule antioxidant therapy protects normal tissue but not tumor tissue in mice with transgenic lung tumors.
Improving the Thermal Stability of NMC 622 Li-Ion Battery Cathodes through Doping During Coprecipitation (2020)

Increasing the Ni content of LiNi<sub><i>x</i></sub>Mn<sub><i>y</i></sub>Co<sub>1-<i>x</i>-<i>y</i></sub>O<sub>2</sub> (NMC) cathodes can increase the capacity, but additional stability is needed to improve safety and longevity characteristics. In order to achieve this improved stability, Mg and Zr were added during the coprecipitation to uniformly dope the final cathode material. These dopants reduced the capacity of the material to some extent, depending on the concentration and calcination temperature. However, these dopants can impart substantial stabilization. It was found that the degree of stabilization is strongly dependent on the calcination temperature of the material. In addition, we used synchrotron X-ray diffraction during thermal breakdown to better understand why the different dopants impact the thermal stability and confirm the stabilization effects of the dopants.
CSM-based feature extraction for degraded machine printed character recognition (2010)

This paper presents an OCR method for degraded character recognition applied to typewritten document produced by typesetting machine. The complementary similarity measure method (CSM) is a well known classification method and widely applied in the area of character recognition. In this work the CSM method is not only used as a classifier but also introduced as a feature extractor, and applied to degraded character recognition. The resulted CSM feature vector is used to train a multi layered perceptron (MLP). The use of the CSM as a feature extractor tends to boost the MLP and makes it very powerful and very well suited for rejection. Experimental results on n typewritten A4 page documents show the ability of the model to yield relevant and robust recognition on poor quality printed document characters.
Design of a linear c-band helix TWT for digital communications experiments using the CHRISTINE suite of large-signal codes (2002)

A set of optimization goal functions designed to improve the efficiency and linearity performance of helix traveling-wave tubes (TWT) is described. These goal functions were implemented in the CHRISTINE suite of large-signal helix TWT codes along with a steepest-descent optimization algorithm to automate the process of circuit parameter variation and to facilitate the rapid exploration of alternative TWT designs. We compare the predicted power, efficiency, and linearity of four different helix TWT circuits, each developed according to a different set of optimization criteria. Out of these designs, a single design was selected to be further developed for use in C-band high-data-rate communications experiments. The detailed design of this linearized TWT with a predicted 1-dB small-signal bandwidth of 1.2 GHz, small-signal centerband gain of 35.7 dB (f/sub c/=5.5 GHz), and centerband saturated output power of 52 dBm (158.5 W) is presented.
Raman Studies of Pb<sub><i>x</i></sub>Sr<sub>1 −<i>x</i></sub>TiO<sub>3</sub>Ceramics and Composites (2004)

Local symmetry breaking in Pb x Sr1 − x TiO3 (PST) solid solutions was revealed by Raman spectroscopy far above the Curie temperature. This effect was remarkably enhanced in PST:MgO composite due to the inhomogeneous grain boundaries and intergrain stresses.
Parallel-Channel Acousto-Optic Modulation (1986)

Design and fabrication considerations for multielectrode modulation in a single acousto-optic device operating in the near acoustic field are presented. In particular, topics including acoustic and electrical cross-talk and electrode apodization to control Fresnel effects of the sound column on diffracted light are discussed; a concept of nesting electrodes to create overlapping laser beams is introduced.
Using economic Model Predictive Control to design sustainable policies for mitigating climate change (2012)

Reducing greenhouse gas emissions is now an important and pressing matter. Systems control theory, and in particular feedback control, can contribute to the design of policies that achieve sustainable levels of emissions of CO <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> (and other greenhouse gases) while minimizing the impact on the economy, and at the same time explicitly addressing the high levels of uncertainty associated with predictions of future emissions. In this paper, preliminary results are described for an approach where economic Model Predictive Control (MPC) is applied to a Regional dynamic Integrated model of Climate and the Economy (RICE model) as a test bed to design savings rates and global carbon tax for greenhouse gas emissions. Using feedback control, the policies are updated on the basis of the observed emissions, rather than on the predicted level of emissions. The basic structure and principle of the RICE model is firstly introduced and some key equations are described. The idea of introducing feedback control is then explained and economic MPC is applied to design policies for CO <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> emissions. Simulation results are presented to demonstrate the effectiveness of the proposed method for two different scenarios. Feedback control design provides a degree of robustness against disturbances and model uncertainties, which is illustrated through a simulation study with two particular types of uncertainties. The results obtained in this paper illustrate the strength of the proposed design approach and form the basis for future research on using systems control theory to design optimal sustainable policies.
Security Analysis of Selected AMI Failure Scenarios Using Agent Based Game Theoretic Simulation (2014)

Information security analysis can be performed using game theory implemented in dynamic Agent Based Game Theoretic (ABGT) simulations. Such simulations can be verified with the results from game theory analysis and further used to explore larger scale, real world scenarios involving multiple attackers, defenders, and information assets. We concentrated our analysis on the Advanced Metering Infrastructure (AMI) functional domain which the National Electric Sector Cyber security Organization Resource (NESCOR) working group has currently documented 29 failure scenarios. The strategy for the game was developed by analyzing five electric sector representative failure scenarios contained in the AMI functional domain. From these five selected scenarios, we characterize them into three specific threat categories affecting confidentiality, integrity and availability (CIA). The analysis using our ABGT simulation demonstrates how to model the AMI functional domain using a set of rationalized game theoretic rules decomposed from the failure scenarios in terms of how those scenarios might impact the AMI network with respect to CIA.
A Journey along the linear viscoelasticity of binary networks from entangled polymers towards their nonlinear rheology (2017)

We report on recent progress made on linear rheology of binary entangled polymers towards their nonlinear transient response. Such well-characterized model systems have been paid attention for more than two decades to probe the elastic instabilities of industrial polymers during the processing. Our main goal is to provide insight on the non-linear shear rheology of binary entangled polymer chains. More specific, we would like to identify the molecular origin of the stress overshoot as well as to thoroughly understand how chain retraction and disentanglement are influenced by the deformation rate and the chain topology (e.g. linear or star chains). In this presentation, we first outline the theoretical framework for understanding the observed linear and nonlinear rheological behavior of such polymeric systems. To do so, we use three different models based on general coarse-grained approaches. Finally we compare our predictions with experimental findings and comment on the performance of the models; we also highlight similarities and/or differences, which we explain in terms of the underlying molecular physics and the way the latter have been implemented in the models.
Radiation Force Acting on a Sphere in a Cylindrical Sound Field (1956)

Corresponding problems of the radiation forces acting on a rigid spherical obstacle in a progressive plane or spherical sound field have been examined previously [L. V. King, Proc. Roy. Soc. (London) A147, 212–240 (1934); T. F. W. Embleton, J. Acoust. Soc. Am. 26, 40–46 (1954)]. In these cases the sound field and scattering obstacle both have symmetry about the line joining the center of the obstacle to the source of the sound field, but for a cylindrical field there exists only a lower degree of symmetry. A more general expression has now been obtained for the radiation force in terms of the complex amplitudes of spherical harmonics required to synthesize the incident sound field—for the cases of greater symmetry this reduces to the simpler expressions previously obtained. The first 20 nonzero amplitudes have been evaluated for a cylindrical sound field, and it is shown that the force is one of attraction near the source, becomes zero at a certain distance, and at a greater distance is a force of repulsion. This is qualitatively the same as for spherical waves, but for any given size of obstacle or frequency of the sound field the point of zero force is always nearer to the source in a cylindrical field. Experimental results will be reported.