gebhart/patrepeval huggingface dataset:
In situ Resonance Raman Spectroscopy of Polyazulene on Aluminum (2008)

Polyazulene (PAz) has been electrochemically deposited on different electrode substrates. The films were characterized with Raman and UV-vis spectroscopy. The spectroelectrochemical studies were performed in situ during p- and n-doping (electrochemical oxidation and reduction, respectively). The focus of this work was mainly on the charging and discharging reactions of PAz on Al substrates. The results were compared to the corresponding results obtained from PAz on Pt substrates. Three different excitation wavelengths (514, 633, and 780 nm) were used in the Raman experiments and the resonance enhancement effect was observed when changing the wavelength of the excitation line. The vibrational behavior of PAz deposited on Al was very similar to that of PAz deposited on Pt during p-doping. Furthermore, it was found that the vibrational responses during p- and n-doping are different indicating that the electronic structure of PAz is not the same during positive and negative charging. It was concluded that PAz is not reversibly n-doped on Al. The n-doping on Pt was shown to be more reversible. In this paper, the important correlation between UV-vis and Raman spectroscopy is discussed as well as the correlation between doping-induced infrared active bands and Raman bands of neutral PAz.
The migration of fin whales into the southern Chukchi Sea as monitored with passive acoustics (2016)

Abstract Fin whales (Balaenoptera physalus) undergo seasonal migration in the Arctic Sea. Because their migration and distribution is likely affected by changes in global climate, we aimed to examine the migration timing of fin whales, and the relationship with prey availability within the oceanographic environment of the Arctic Sea, using passive and active acoustic monitoring methods. Automatic Underwater Sound Monitoring Systems were deployed in the southern Chukchi Sea from July 2012 to 2014 to determine the acoustic presence of fin whales. Furthermore, water temperature and salinity were recorded by a fixed data logger. An Acoustic Zooplankton Fish Profiler was additionally deployed to estimate prey abundance through backscattering strength. Sea ice concentrations were obtained by remote sensing data. Fin whale calls were automatically detected using a custom-made software, and the per cent of half-hours containing calls were counted. Fin whale calls were detected from 4 August to 20 October 2012 (78 d) and 25 July to 1 November 2013 (100 d). The extended period of acoustic presence of fin whales during 2013 when compared with 2012 is likely related to a longer ice-free period during 2013. Furthermore, generalized linear model analyses showed that half-hour periods containing calls increased with a rise in water temperature and zooplankton abundance during the initial call presence period, while they decreased with a decrease in water temperature and salinity during the end of the call presence period. Our results suggest that the rise in water temperature and zooplankton abundance affect the timing of migration of fin whales in a way that is consistent with the expansion of their suitable habitats and the extension of their presence in the Arctic Sea.
The kinetically dominant assembly pathway for centrosomal asters in <i>Caenorhabditis elegans</i> is γ-tubulin dependent (2002)

gamma-Tubulin-containing complexes are thought to nucleate and anchor centrosomal microtubules (MTs). Surprisingly, a recent study (Strome, S., J. Powers, M. Dunn, K. Reese, C.J. Malone, J. White, G. Seydoux, and W. Saxton. Mol. Biol. Cell. 12:1751-1764) showed that centrosomal asters form in Caenorhabditis elegans embryos depleted of gamma-tubulin by RNA-mediated interference (RNAi). Here, we investigate the nucleation and organization of centrosomal MT asters in C. elegans embryos severely compromised for gamma-tubulin function. We characterize embryos depleted of approximately 98% centrosomal gamma-tubulin by RNAi, embryos expressing a mutant form of gamma-tubulin, and embryos depleted of a gamma-tubulin-associated protein, CeGrip-1. In all cases, centrosomal asters fail to form during interphase but assemble as embryos enter mitosis. The formation of these mitotic asters does not require ZYG-9, a centrosomal MT-associated protein, or cytoplasmic dynein, a minus end-directed motor that contributes to self-organization of mitotic asters in other organisms. By kinetically monitoring MT regrowth from cold-treated mitotic centrosomes in vivo, we show that centrosomal nucleating activity is severely compromised by gamma-tubulin depletion. Thus, although unknown mechanisms can support partial assembly of mitotic centrosomal asters, gamma-tubulin is the kinetically dominant centrosomal MT nucleator.
L’intensité de l’odeur des mélanges binaires de composés odorants (2002)

This paper presents the MBO model for the perceived intensity of odour mixtures. This model is based on an equation previously reported by our team, intended to model the whole stimulus-response intensity curve of pure odorous compounds. The MBO model was applied to a set of published data, and compared to other published models. The results show a high modelling efficiency of the MBO model compared to other proposed equations, especially for binary mixtures exhibiting significant asymmetry of intensity for different ratios of the two components. Furthermore, the MBO model includes parameters specific to the respective effects of each component in the mixture, which may help to clarify the masking and synergy effects that are often sought in odour mixtures.
Synthesis and Properties of ω‐Substituted Alkyltin Derivatives and of Copolymerizable ω‐Alkenyltin Compounds (1973)

Abstract This paper describes the synthesis and spectroscopic identification of ω‐undecenyl‐, ω‐butenyl‐ and ω‐pentenyltriphenyltin compounds. Those of ω‐phenyl‐ and ω‐phenoxyalkyltin derivatives are also given.
Tremorgenic Toxins from Penicillia (1971)

A low temperature (4 C) favors the accumulation of the mycotoxin tremortin when tremortin-producing molds are grown on various agricultural commodities. However, the rate of toxin formation is more rapid at a high temperature (20 C).
In Situ Analysis of the Growth and Dielectric Properties of Organic Self-Assembled Monolayers: A Way To Tailor Organic Layers for Electronic Applications (2016)

Organic nanoscale science and technology relies on the control of phenomena occurring at the molecular level. This is of particular importance for the self-assembly of molecular monolayers (SAM) that can be used in various applications ranging from organic electronics to bioelectronic applications. However, the understanding of the elementary nanoscopic processes in molecular film growth is still in its infancy. Here, we developed a novel in situ and extremely sensitive detection method for the analysis of the electronic properties of molecular layer during molecular layer deposition. This low-frequency sensor (1 kHz) is employed to analyze the standard vapor deposition process of SAMs of molecules and, subsequently, it is used to optimize the growth process itself. By combining this method with an ex situ determination of the effective thickness of the resulting layers via ellipsometry, we observe a large difference of the permittivity (1 kHz) of the examined aminosilanes in the liquid state (εliquid = 5.5-8.8) and in SAMs (εSAM = 22-52, electric field in the plane of the layer). We ascribe this difference to either the different orientation and order of the molecules, the different density of molecules, or a combination of both effects. Our novel in situ analyses not only allows monitoring and optimizing the deposition of organic layers but also demonstrates the high potential of organic SAMs as organic high-k layers in electronic devices.
β1-Adrenergic Receptor Association with the Synaptic Scaffolding Protein Membrane-associated Guanylate Kinase Inverted-2 (MAGI-2) (2001)

The beta1-adrenergic receptor (beta1AR) is known to be localized to synapses and to modulate synaptic plasticity in many brain regions, but the molecular mechanisms determining beta1AR subcellular localization are not fully understood. Using overlay and pull-down techniques, we found that the beta1AR carboxyl terminus associates with MAGI-2 (membrane-associated guanylate kinase inverted-2), a protein also known as S-SCAM (synaptic scaffolding molecule). MAGI-2 is a multidomain scaffolding protein that contains nine potential protein-protein interaction modules, including 6 PDZ domains, 2 WW domains, and a guanylate kinase-like domain. The beta1AR carboxyl terminus binds with high affinity to the first PDZ domain of MAGI-2, with the last few amino acids of the beta1AR carboxyl terminus being the key determinants of the interaction. In cells, the association of full-length beta1AR with MAGI-2 occurs constitutively and is enhanced by agonist stimulation of the receptor, as assessed by both co-immunoprecipitation experiments and immunofluorescence co-localization studies. Agonist-induced internalization of the beta1AR is markedly increased by co-expression with MAGI-2. Strikingly, this result is the opposite of the effect of co-expression with PSD-95, a previously reported binding partner of the beta1AR. Further cellular experiments revealed that MAGI-2 has no effect on beta1AR oligomerization but does promote association of beta1AR with the cytoplasmic signaling protein beta-catenin, a known MAGI-2 binding partner. These data reveal that MAGI-2 is a specific beta1AR binding partner that modulates beta1AR function and facilitates the physical association of the beta1AR with intracellular proteins involved in signal transduction and synaptic regulation.
Molecular epidemiology and characterization of multiple drug-resistant (MDR) clinical isolates of Acinetobacter baumannii (2015)

This study supports a more complete understanding of genotyping of antibiotic resistance for better assessment of MDR strain transmission.
Effect of inhomogeneous broadening on the surface photochemistry of phthalazine (1999)

The amount of photoproduct of phthalazine adsorbed on silver surfaces was examined by observing SERS spectra. Some of the phthalazine adsorbed on silver surface did not photoreact even with prolonged irradiation and the relative amount of photoproduct was larger on irradiation with two or multi laser wavelengths than with one. This is interpreted as reflecting inhomogeneous broadening of the excited state of molecules adsorbed on metal surfaces. Copyright © 1999 John Wiley & Sons, Ltd.
Solution Structure of the Supramolecular Adduct between a Liver Cytosolic Bile Acid Binding Protein and a Bile Acid-Based Gadolinium(III)-Chelate, a Potential Hepatospecific Magnetic Resonance Imaging Contrast Agent (2008)

Bile acid-conjugated gadolinium chelates were shown to display promising features for the development of hepatospecific constrast agents for magnetic resonance imaging (MRI). The study of the pharmacokinetics of these compounds should address their possible interaction with the bile acid protein transporters. We have previously shown that a 5beta-cholanoic acid-based contrast agent is efficiently internalized in hepatocytes and is able to bind to a liver bile acid binding protein (BABP) in vitro. Here we report the solution structure of the adduct between a BABP and a gadolinium chelate/bile acid conjugate. The identification of unambiguous intermolecular distance restraints was possible through 3D edited/filtered NOESY-HSQC experiments, together with distance information derived from paramagnetic relaxation enhancements. These intermolecular contacts were used for the structure determination of the complex, using the data-driven docking software HADDOCK. The obtained results represent the starting point for the design of new and more efficient MRI contrast agents.
High dose Erythropoietin increases Brain Tissue Oxygen Tension in Severe Vasospasm after Subarachnoid Hemorrhage (2012)

EPO increases PbtO2 in poor grade SAH patients with severe cerebral vasospasm. The effect on outcome needs further investigation.
Über den Einfluss langjährigen Zigarettenrauchens auf die Lungenfunktion jugendlicher Normalpersonen (1972)

Spirometric and plethysmographic measurements combined with investigations of lung PV-characteristics by means of oesophageal catheters were carried out in both 20 young healthy smokers and 20 non-smokers. The mean age of all probands was 29 years. The following results were obtained: (1) Spirometric data andairway resistance were normal in all subjects. Viscous work of breathing, however, was significantly elevated in cigarette smokers. (2) The static elastic recoil pressures of all subjects fell within the normal limits given by Turner in 1968. (3) Significance of long-termed cigarette smoking was demonstrated by a rise of static compliance and a pronounced frequency dependence of dynamic compliance. Respiratory findings present in cigarette smokers are related to peripheral airway changes. In addition, smoke-specific lesions may be due to disturbances of alveolar surfactant.
Regulator of Dendrite and Synapse Formation (2004)

Two papers by Shi et al. describe a receptor-like molecule that functions in the formation and maturation of dendrites, the specialized regions of neurons where they receive input from other neurons. Having noted genetic evidence from Drosophila that a protein from the immunoglobulin superfamily appeared to function in the formation of dendrites, the authors searched for and identified a mouse protein they named Dasm1, for dendrite arborization and synapse maturation. In cultured rat hippocampal neurons, loss of Dasm1 inhibited the outgrowth of dendrites but not of axons. To examine later stages of synapse formation, the authors prepared hippocampal slices from 8-day-old rats and found that inhibition of Dasm1 function reduced the acquisition of signaling through AMPA α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid) receptors that is normally associated with synapse maturation. Two possible binding partners for Dasm1 are the proteins Shank (Src homology 3 domain- and ankyrin repeat-containing protein) and S-SCAM (synaptic scaffolding molecule), which have been implicated previously in the regulation of synaptic function. Thus, Dasm1 may transduce extracellular signals in postsynaptic neurons, regulating cytoskeletal organization and synaptic expression of neurotransmitter receptors. — LBR
Quasi-1D Bose-Einstein condensates in the dimensional crossover regime (2004)

International audience
Wave patterns generated by disturbances travelling horizontally in rotating stratified fluids (1975)

The pattern and propagation of waves generated by steady or oscillatory disturbances travelling horizontally in a rotating, stratified fluid are studied following a technique developed by Lighthill. Both two‐ and three‐dimensional distrubances are investigated. The results show how rotation modifies internal wave patterns in a stratified fluid and how stratification modifies inertial wave patterns in a rotating fluid. The results are used to compute the effective diminution of Taylor column length due to the presence of density stratification. They also show that the appearance of wave crests upstream of a disturbance is possible only when the disturbance is unsteady and that observations of upstream blocking in a two‐dimensional stratified flow can be explained by the existence of a certain class of plane waves as modified by viscosity.
Nuclear fuel performance in boiling water reactors (1981)

A major development program is described to improve the performance of Boiling Water Reactor fuel. This sustained program is described in four parts: 1) performance monitoring, 2) fuel design changes, 3) plant operating recommendations, and 4) advanced fuel programs.
Endovascular management of pseudo-aneurysms after previous surgical repair of congenital aortic coarctation (2007)

The endovascular management of pseudo-aneurysms after previous surgical repair of congenital aortic coarctation is feasible. This approach was safe and effective. Long-term clinic and imaging follow-up is mandatory.
Optical printed circuit board (O-PCB) and VLSI photonic integrated circuits: visions, challenges, and progresses (2006)

A collective overview and review is presented on the original work conducted on the theory, design, fabrication, and in-tegration of micro/nano-scale optical wires and photonic devices for applications in a newly-conceived photonic systems called "optical printed circuit board" (O-PCBs) and "VLSI photonic integrated circuits" (VLSI-PIC). These are aimed for compact, high-speed, multi-functional, intelligent, light-weight, low-energy and environmentally friendly, low-cost, and high-volume applications to complement or surpass the capabilities of electrical PCBs (E-PCBs) and/or VLSI electronic integrated circuit (VLSI-IC) systems. These consist of 2-dimensional or 3-dimensional planar arrays of micro/nano-optical wires and circuits to perform the functions of all-optical sensing, storing, transporting, processing, switching, routing and distributing optical signals on flat modular boards or substrates. The integrated optical devices include micro/nano-scale waveguides, lasers, detectors, switches, sensors, directional couplers, multi-mode interference devices, ring-resonators, photonic crystal devices, plasmonic devices, and quantum devices, made of polymer, silicon and other semiconductor materials. For VLSI photonic integration, photonic crystals and plasmonic structures have been used. Scientific and technological issues concerning the processes of miniaturization, interconnection and integration of these systems as applicable to board-to-board, chip-to-chip, and intra-chip integration, are discussed along with applications for future computers, telecommunications, and sensor-systems. Visions and challenges toward these goals are also discussed.
Spectrum and Contour Analysis of Ultrasonic Pulses for the Determination of Microstructure in Metals (1960)

The attenuation of ultrasonic energy in metals depends on the ratio of the ultrasonic wavelength to the grain diameter. Hence, microstructure can be determined by measuring the relative rate of energy loss in a specimen at various ultrasonic frequencies. Unfortunately, such measurements are extremely time consuming. A theoretical and experimental investigation carried out at Watertown Arsenal Laboratories indicates, however, that the desired relationship between ultrasonic attenuation and frequency can be obtained in a very quick manner if the test is carried out with ultrasonic pulses of rectangular envelope. Such pulses contain ultrasonic energy distributed over a fairly wide spectrum, and the influence of a frequency dependent energy loss can he determined either by spectrum or contour analysis of the attenuated ultrasonic signal.
Efficacy and Safety of Desensitization With Sulfamethoxazole and Trimethoprim in 48 Previously Hypersensitive Patients Infected With Human Immunodeficiency Virus (1997)

The efficacy of desensitization with sulfamethoxazole-trimethoprim was confirmed; this desensitization procedure was more often successful in patients with lower CD4+ cell percentages and CD4+/CD8+ ratios. However, sulfamethoxazole-trimethoprim therapy should be reintroduced carefully.
Site-specific assessment of a 150-MW coal gasification fuel cell power plant. Final report (1983)

The biological control bacterium Pseudomonas chlororaphis (aureofaciens) strain 30-84 employs two quorum sensing (QS) systems: PhzR/PhzI regulates the production of the antibiotics phenazine-1-carboxylic acid, 2-hydroxy-phenazine-1-carboxylic acid, and 2-hydroxy-phenazine, whereas CsaR/CsaI regulates currently unknown aspects of the cell surface. Previously characterized derivatives of strain 30-84 with mutations in each QS system and in the phenazine biosynthetic genes were screened for their ability to form surface-attached biofilm populations in vitro, using microtiter plate and flow cell biofilm assays, and on seeds and roots. Results from in vitro, seed, and root studies demonstrated that the PhzR/PhzI and the CsaR/CsaI QS regulatory systems contribute to the establishment of biofilms, with mutations in PhzR/PhzI having a significantly greater effect than mutations in CsaR/CsaI. Interestingly, phenazine antibiotic production was necessary for biofilm formation to the same extent as the PhzR/PhzI QS system, suggesting the loss of phenazines was responsible for the majority of the biofilm defect in these mutants. In vitro analysis indicated that genetic complementation or AHL addition to the growth medium restored the ability of the AHL synthase phzI mutant to form biofilms. However, only phenazine addition or genetic complementation of the phenazine biosynthetic mutation in trans restored biofilm formation by mutants defective in the transcriptional activator phzR or the phzB structural mutant. QS and phenazine production were also involved in the establishment of surface-attached populations on wheat seeds and plant roots, and, as observed in vitro, the addition of AHL extracts restored the ability of phzI mutants, but not phzR mutants, to form surface attached populations on seeds. Similarly, the presence of the wild type in mixtures with the mutants restored the ability of the mutants to colonize wheat roots, demonstrating that AHL and/or phenazine production by the wild-type population could complement the AHL- and phenazine-deficient mutants in situ. Together, these data demonstrate that both QS systems are involved in the formation of surface-attached populations required for biofilm formation by P. chlororaphis strain 30-84, and indicate a new role for phenazine antibiotics in rhizosphere community development beyond inhibition of other plant-associated microorganisms.
Building recommendation systems using peer-to-peer shared content (2010)

Peer-to-Peer (p2p) networks are used for sharing content by millions of users. Often, meta-data used for searching is missing or wrong, making it difficult for users to find content. Moreover, searching for new content is almost impossible. Recommender systems are unable to handle p2p data due to inherent difficulties, such as implicit ranking, noise and the extreme dimensions and sparseness of the network.
Metabolic and mind shifts (2015)

Oxidative decarboxylation and reductive carboxylation of αKG represent two options for the glutamine metabolism. The canonical forward mode of the TCA cycle fuelled by glutamine may benefit from the decarboxylation of malate into pyruvate for fueling pyruvate dehydrogenase and generating acetyl-CoA to offer a self-sustainable TCA cycle. Under hypoxia and mutations in the TCA cycle, the reductive carboxylation of glutamine-derived αKG into citrate mainly supports lipogenesis via the ATP citrate lyase that cleaves citrate into oxaloacetate and acetyl-CoA. Still, a largely unsuspected source of acetyl-CoA was shown to derive from the direct ligation of acetate to CoA by acetyl-CoA synthetases. Altogether, these findings identify critical metabolic nodes in the glutamine and acetate metabolism as new determinants of tumor metabolic plasticity that may facilitate the design of synthetic lethal treatments.
Synthèse d'analogues acycliques de C‐nucléosides (1983)

Abstract Synthèse d'analogues acycliques de nucléosides où la chaîne est liée à la base hétérocyclique par une liaison carbone‐carbone. Nous décrivons une méthode directe pour la préparation de dérivés de la guanine et de la s ‐triazolo[1,5‐ a ]pyridine.
Photopumping of innershell transitions by relativistic plasmas (2001)

A 130 fs 200 mJ titanium saphire laser is used to investigate conditions of generating inversion on an innershell transition in cobalt. Using a longitudinal pumping geometry copper K-shell radiation is used to photopump cobalt K α , The amount of photopumping is determined by comparing the generated cobalt radiation with the one of nickel, for which photopumping by copper K α is not possible. Using a specially designed target with a vacuum gap in between the pump and the medium to be pumped we observe a photopumped fraction of over 90 %. The vacuum gap holds back the electrons which generate L-holes and thus destroy the inversion.