gebhart/patrepeval huggingface dataset:
ACTIVATION OF HUMAN T CELLS IN VIVO FOLLOWING TREATMENT OF TRANSPLANT RECIPIENTS WITH OKT3 (1990)

Sequential lymph node biopsies were obtained prior to and following OKT3 administration in 10 organ transplant recipients to determine whether activation of human T cells occurs in vivo during OKT3 administration. Within 2 hr after injection, OKT3 can be detected coating LN T cells, and LN T cells also demonstrate enhanced proliferation in vitro in the presence of recombinant interleukin-2 (rIL-2). Interleukin-2 receptor (IL-2R) is expressed on post-OKT3 LN T cells within 48 hr following administration of OKT3. In addition, when placed in a mixed lymphocyte reaction, post-OKT3 LN cells also demonstrate enhanced proliferation. This is the first direct demonstration of in vivo activation of human T cells by OKT3. These data support the hypothesis that T lymphocyte activation and concomitant production of lymphokines are responsible for the side effects associated with OKT3 treatment. Immune activation and possible enhancement of anti-donor MHC alloreactivity may have significant implications for anti-CD3 and anti-TCR monoclonal antibody therapy in clinical organ transplantation and for enhancement of the immune response in cancer patients.
Modernist Retrocessions: Homosexual Transgression, Representation, and the Theatre of Brazilian Modernism (2002)

This essay is part of a chapter of my forthcoming book, Tentative Transgressions: Homosexuality, AIDS and the Theatre in In that chapter, I look at how three major twentieth-century playwrights, Nelson Rodrigues, Oswald de Andrade and Plinio Marcos represent homosexual transgression. Nelson, Oswald and Plinio, it goes without saying, are names whose immense iconic stature in Brazilian culture calls for frequent reinterpretation. What I argue in my book is that the theatre of these men in portraying gays and lesbians, although sporting a veneer of modernity and acceptance, harked back to a period which vilified difference and thus excluded most signs of the fluid nature of gender identification in Brazil. Such exclusionary practices continued in fact into the next generation of dramatists, and it was not until the midto late-1970s that a new approach to the representation of homosexuality began to appear on the Brazilian stage. Still, the picture is hardly a black and white one, for the plays I examine in that chapter?Oswalds O Rei da Vela [pubi. 1937; perf. 1967], Nelsons Alb um de Fam?lia [pubi. 1946; perf. 1967], Beijo no Asfalto [pubi, and perf. 1961], and Toda Nudez Ser? Castigada [perf. 1965; pubi. 1966], as well as Marcos s Navalha na Carne and Dois Perdidos numa Notte Suja, which are generally included among the best Brazilian theatre ever produced, when interrogated along the lines of transgression and gay representation, offer themselves up to new readings and allow new perceptions (previously neglected or repressed) to surface. As Modernism gained control of the intellectual territory in 1920s Brazil, it disregarded some public figures and cultural manifestations that either had prefigured the movement or that shared certain features and interests with it. Prominent among such figures and manifestations were the prolific writer, playwright, and journalist Joao do Rio (Paulo Barreto, 1881-1921) and the Luso-Brazilian version of the light theatre revue, or teatro de revista.
Hemoperitoneo espontáneo secundario a rotura de pseudoquiste pancreático: una causa inusual de muerte inesperada (2015)

Presentamos un caso de fallecimiento por hemoperitoneo masivo espontaneo como complicacion tardia de un
pseudoquiste pancreatico de evolucion torpida. Se trata de una causa muy infrecuente de hemoperitoneo espontaneo en la literatura
medica. Se describen los hallazgos histopatologicos de erosion de arteria pancreatico-duodenal y diseccion de la pared duodenal.
Poly-<scp>l</scp>-lysine Produced by Streptomyces. Part III. Chemical Studies (1981)

Journal Article Poly-l-lysine Produced by Streptomyces. Part III. Chemical Studies Get access Shoji Shima, Shoji Shima Department of Agricultural Chemistry, College of Agriculture, University of Osaka Prefecture, Sakai, Osaka 591, Japan Search for other works by this author on: Oxford Academic Google Scholar Heiichi Sakai Heiichi Sakai Department of Agricultural Chemistry, College of Agriculture, University of Osaka Prefecture, Sakai, Osaka 591, Japan Search for other works by this author on: Oxford Academic Google Scholar Agricultural and Biological Chemistry, Volume 45, Issue 11, 1 November 1981, Pages 2503–2508, https://doi.org/10.1080/00021369.1981.10864930 Published: 01 November 1981 Article history Received: 20 April 1981 Published: 01 November 1981
Water Meters 101: Consider Your Options (2015)

Public water systems meter each service connection's or customer's water usage to determine billing charges and to track water use. The meter types commonly used in water systems help utilities determine the right meter for the required application.
Intratumoral delivery of paclitaxel-loaded poly(lactic-co-glycolic acid) microspheres for Hep-2 laryngeal squamous cell carcinoma xenografts (2007)

The introduction of induction chemotherapy provides an expectation of laryngeal function preservation without reduction in survival for patients with advanced laryngeal squamous cell carcinoma. The antitumor activity of conventional intravenous chemotherapy, however, is limited by systemic toxicity. The polymeric drug system delivered locally provides a novel modality of increasing therapeutic concentrations of drug for a prolonged period while decreasing systemic levels. In the current study, paclitaxel-loaded sustained-release microspheres were developed using poly(lactic-co-glycolic acid) as a drug carrier. Intratumoral administration of paclitaxel in the formulation of polymer showed enhanced efficacy against laryngeal squamous cell carcinoma in nude mice compared with conventional paclitaxel injection via the intratumoral or intraperitoneal route. No significant toxic reactions were observed in the experiment. Immunohistochemical findings indicated that paclitaxel exhibited antiangiogenic activity by inhibiting the expression of basic fibroblast growth factor and vascular endothelial growth factor within the tumor. Moreover, this effect could be better exploited via localized delivery of polymeric paclitaxel. In conclusion, direct administration of polymeric drug system at the tumor sites proved to be promising for the treatment of laryngeal carcinoma.
[Origin and Regulation of Hematopoietic Stem Cells During Embryonic Ontogeny] (2000)

Stem cells of various tissues including hematopoietic tissue in the body are derived from embryonic stem cells (ESC). There exists intricated gene regulation during ESC development and its differentiation into hematopoietic stem cells (HSC). In embryo hematopoiesis development, there are two kinds of hematopoietic types, primitive hematopoiesis and definitive hematopoiesis. The theory of the yolk sac of primitive hematopoiesis is well accepted, while the initial site of definitive hematopoiesis still exists controversy. In present opinion, there are at least two independent sites associated with definitive hematopoiesis, those are, yolk sac and para-aortic splanchnopleura (PAS)/aorta-gonad mesonephros (AGM). Study on the hematopoiesis and its regulation during embryonic ontogeny will benefit not only to the dicovery of the mechanism of some blood disorders, but as well to gene therapy and HSC engineering.
Graph Partitioning Based Normalized Cut Methods (2014)

The process of image segmentation is one of the most important steps in computer vision for image retrieval, visual summary, image based modeling and in many other processes. The goal of segmentation is typically to locate certain objects of interest. In this paper, we have studied and investigated graph based normalized cut segmentation methods and proposed a technique for adding flexibility to the parameters for performance improvement. These methods are examined analytically and tested their performance for the standard images. The results obtained for the important metrics show that these methods perform better than others approaches and are computationally efficient, and useful for precise image segmentation.
Interlanguage working without tears (1999)

A good foreign-language interface is crucial for the success of any modern programming language implementation. Although all serious compilers for functional languages have some facility for interlanguage working, these are often limited and awkward to use.This article describes the features for bidirectional interlanguage working with Java that are built into the latest version of the MLj compiler. Because the MLj foreign interface is to another high-level typed language which shares a garbage collector with compiled ML code, and because we are willing to extend the ML language, we are able to provide unusually powerful, safe and easy to use interlanguage working features. Indeed, rather then being a traditional foreign interface, our language extensions are more a partial integration of Java features into SML.We describe this integration of Standard ML and Java, first informally with example program fragments, and then formally in the notation used by The Definition of Standard ML.
The Effect of Nitrogen Starvation on the Activity of Nitrate Reductase and other Enzymes in Chlorella (1965)

Chlorella vulgaris grown with nitrate as nitrogen source had high nitrate reductase activity. During nitrogen starvation the rate of nitrate assimilation increased but the specific activity of nitrate reductase in extracts decreased sharply; a similar decrease occurred after transfer to an ammonium medium. Organisms grown with ammonium as nitrogen source did not assimilate nitrate but acquired the ability to do so after nitrogen starvation; nitrate reductase activity in these organisms was initially very low but increased during nitrogen starvation and then decreased. After 18 hr of nitrogen starvation ammonium-grown and nitrate-grown organisms assimilated nitrate rapidly at a rate some ten times greater than the activity of nitrate reductase in cell-free extracts would allow. The specific activity of glutamic dehydrogenase was about 40% higher in extracts from ammonium-grown organisms than in extracts from nitrate-grown organisms and its activity increased by 40-100 % during nitrogen starvation. The activity of malic dehydrogenase was unaffected by 18 hr of nitrogen starvation. The activity of isocitrate lyase decreased by about one-quarter when acetate was present but decreased much more markedly when the organisms were nitrogen-starved in the presence of glucose.
Notes on Paha Buyang (2006)

This paper is an outline of some of the major features of the phonology and grammar of a dialect of the Buyang language, a Tai-Kadai language with roughly 2000 speakers spread over the border area of Yunnan and Guangxi Provinces in China, and northern Vietnam and Laos. The particular variety described is the Paha variety spoken in Yanglian village, Guangnan County in Yunnan Province, China. The genetic position of Buyang within Tai-Kadai, and the influence of Zhuang and Chinese on the language are also discussed.
An Evaluation of Field Techniques in Detection of Deception (1975)

ABSTRACT Field techniques of detecting deception were evaluated using a mock crime situation. Thirty‐six Ss were “guilty” of taking $10, and 36 Ss were “innocent,” A field‐type interview was followed by a zone comparison control‐question polygraph examination. A Keeler field polygraph was used to record physiology activity, and field (semi‐objective) and quantitative evaluations of the charts were made. Those who evaluated the charts were not informed about the “guilt” or “innocence” of each S. Using field evaluations, there were 53% correct. 12% incorrect, and 35% inconclusives. Excluding inconclusives there were 81% correct decision. using quantitative scoring, significant discriination between “guilty” and “innocent” was obtaindd with skin resistance, cardiovascular, and respiration measures, with skin resistance best. Field evaluations also produced significant discrimination for all three measures. Blind evaluations of the charts by 5 additional examiners produced high agreement among examiner decisions and a mean correlation of .86 among total scores. Thus, the effectiveness of commonly used field techniques and equipment in differentiating truth and deception was demonstrated in a laboratory setting.
MOS transconductors and integrators with high linearity (1986)

MOS transconductors are discussed in which the transistors determining the transconductance do not carry bias current, operate with large gate-source voltage, and are signal-driven in such a way that their nonlinearities are eliminated. An integrator implemented using one of the proposed circuits exhibited measured total harmonic distortion of less than 0.1% for differential input signals of 2.5 V p-p, and less than 1% for 5 V p-p.
The ATP-activated Hexameric Helicase of Bacteriophage T4 (gp41) Forms a Stable Primosome with a Single Subunit of T4-coded Primase (gp61) (1996)

We have examined the formation of the primosome subassembly of the bacteriophage T4-coded DNA replication (elongation) complex from its helicase, primase, and DNA components. Previously, we had shown that the T4 helicase (gp41) exists in solution in a stable monomer left and right arrow dimer equilibrium at physiological protein (and salt) concentrations and forms a hexamer upon activation by ATP (or GTP) binding (Dong, F., Gogol, E. P., and von Hippel, P. H.(1995) J. Biol. Chem. 270, 7462-7473). Here we report that the T4 primase (gp61) is a monomer in solution under the same conditions, and that the ATP-activated helicase binds to a single gp61 primase molecule on appropriate DNA templates to reconstitute a stable primosome. We show that: (i) the gp41 helicase alone does not form a stable complex with DNA templates, although this helicase by itself can carry out moderately processive ATP-driven translocation along single-stranded DNA (Young, M. C., Schultz, D. E., Ring, D., and von Hippel, P. H.(1994) J. Mol. Biol. 235, 1447-1458); (ii) the primase alone does form a stable complex with DNA; (iii) the helicase can bind to the primase-DNA complex in the presence of ATP or GTP to form a stable ternary complex; (iv) this complex consists of six helicase subunits and one primase subunit; and (v) the reconstituted primosome is stable for at least 10 to 20 min after NTP cleavage and dissociation of the hydrolysis products. These results strongly suggest that the functional T4 DNA replication primosome consists of an integrated 6:1 helicase-primase complex bound to DNA, and that the ATP-activated helicase hexamer remains intact throughout the processive DNA replication process.
Decreased expression of NKG2D, NKp46, DNAM-1 receptors, and intracellular perforin and STAT-1 effector molecules in NK cells and their dim and bright subsets in metastatic melanoma patients (2014)

Although natural killer (NK) cells play an important antitumor role, melanoma cells may affect their effector functions. In this study, we analyzed the expression of various receptors and effector molecules in NK cells and their subsets in metastatic melanoma (MM) patients compared with healthy controls (HCs). In HC and MM patients, we analyzed NK cell activity using a chromium release assay and the expression of CD107a degranulation marker, activating NKG2D, NKp46, DNAM-1, and inhibitory CD158a and CD158b receptors, IL-12R beta 1, IL-12R beta 2, intracellular interferon (IFN)-γ, perforin, and STAT-1 in CD3-CD56+ NK cells, and cytotoxic CD3-CD56 and immunoregulatory CD3-CD56 subsets by flow cytometry. MM patients compared with HC not only had significantly decreased NK cell activity, lower expression of CD107a, and impaired IFN-γ production but also had decreased expression of activating NKG2D, NKp46, and DNAM-1 receptors, which was followed by lower expression of perforin, STAT-1, and both IL-12R subunits in NK cells. In MM patients only, there was a positive correlation between NKG2D expression and degranulation capacity, as well as IFN-γ production in NK cells. Analysis of the expression of various parameters of NK cell effector functions between MM patients with different localization of distant metastases showed that patients in the unfavorable M1c subclass had decreased expression of NKG2D and NKp46 on NK cells compared with patients in the M1a+b group. Downregulated NKG2D, NKp46, and DNAM-1 receptors associated with impaired NK cell effector function are important biomarkers of advanced disease with a poor prognosis in melanoma patients.
ANTICONCEPCIÓN DE EMERGENCIA. MÉTODO PARA PREVENIR EMBARAZOS. SE APLICA DESPUÉS DE LA RELACIÓN SEXUAL (2002)

LA ANTICONCEPCION DE EMERGENCIA (AE) ES EL UNICO METODO QUE PUEDE PREVENIR UN EMBARAZO DESPUES DE UNA RELACION SEXUAL NO PROTEGIDA. ES SEGURA -NO TIENE CONTRAINDICACIONES- Y EFECTIVA HASTA EN UN 95 POR CIENTO, SI SE SUMINISTRA DURANTE LAS SIGUIENTES 24 HORAS DESPUES DEL COITO. ESTO ASEGURO SUSANA MEDINA, ESPECIALISTA DE LA ASOCIACION CIVIL THE POPULATION COUNCIL, AL PARTICIPAR EN LA CONFERENCIA ME PROTEJO PORQUE TE QUIERO, ORGANIZADA POR EL CENTRO DE ESTUDIOS EN CIENCIAS DE LA COMUNICACION DE LA FACULTAD DE CIENCIAS POLITICAS Y SOCIALES. EXPLICO QUE LA AE, AMPLIAMENTE ACEPTADA POR LAS USUARIAS, ES UN METODO APROBADO Y RECOMENDADO POR LAS autorIDADES SANITARIAS INTERNACIONALES, EN ESPECIAL POR LA ORGANIZACION MUNDIAL DE LA SALUD (OMS), LA CUAL HA EXHORTADO A LOS PAISES A INCLUIRLA EN SUS NORMAS DE SALUD. SE TRATA DE UN METODO APROPIADO PARA MUJERES QUE TUVIERON UNA RELACION SEXUAL NO PROTEGIDA O CON ROMPIMIENTO DEL CONDON O PRODUCTO DE UNA VIOLACION; ADEMAS, EVITA EMBARAZOS NO DESEADOS E IMPIDE ABORTOS INDUCIDOS. RECORDO QUE A PESAR DE SER USADO DESDE HACE CERCA DE 30 ANOS, ESTE METODO ES POCO CONOCIDO. A DIFERENCIA DE LOS TRADICIONALES, LOS CUALES PREVIENEN EL EMBARAZO ANTES O DURANTE EL COITO, DIJO, LA AE PUEDE EVITARLO UNAS HORAS DESPUES DE LA RELACION SEXUAL, LO CUAL ES POSIBLE MEDIANTE EL USO DE PASTILLAS ANTICONCEPTIVAS NORMALES EN DOSIS CONCENTRADAS Y POR CORTO TIEMPO. EL REGIMEN MAS CONOCIDO DE LA AE ES EL YUZPE, QUE CONSISTE EN DOSIS DETERMINADAS DE LOS COMPUESTOS QUIMICOS TINILESTRADIOL O NORGESTREL. AGREGO QUE EL USO DE LA ANTICONCEPCION DE EMERGENCIA PUEDE TENER EFECTOS SECUNDARIOS; ENTRE LOS MAS COMUNES EST N LAS NAUSEAS, VOMITO, DOLOR DE CABEZA, HIPERSENSIBILIDAD DE LOS SENOS Y RETENCION DE LIQUIDOS; TODOS DESAPARECEN EN 24 HORAS. EN SU INTERVENCION, BENJAMIN RUIZ, ESPECIALISTA EN EL TEMA DEL SEXO SEGURO, CONSIDERO QUE ACTUALMENTE NO SOLO HAY QUE PREVENIR EMBARAZOS NO DESEADOS, SINO TAMBIEN PROTEGERSE DEL VIRUS DE INMUNODEFICIENCIA HUMANA (VIH), CAUSANTE DEL SIDA, ASI COMO DE ALGUNA OTRA ENFERMEDAD DE TRANSMISION SEXUAL. PRECISO QUE EL SEXO SEGURO ES AQUEL QUE CANCELA EL INTERCAMBIO DE FLUIDOS QUE PUEDAN CONTENER EL VIH Y CONSISTE EN USAR CONDON EN TODAS LAS RELACIONES SEXUALES. MAYOR INFORMACION: WWW.EN3DIAS.ORG.MX O EN EL 01-800-363-3427. LA LLAMADA ES GRATUITA Y CONFIDENCIAL.
ANALOGS AND DERIVATIVES OF FIREFLY OXYLUCIFERIN, THE LIGHT EMITTER IN FIREFLY BIOLUMINESCENCE (1991)

The 5-methyl analog of firefly oxyluciferin, two isomeric O-methyl ether derivatives of it and an O,O'-dimethyl ether derivative were synthesized and their UV absorption and fluorescence emission spectra were determined. Comparisons of the emission data with the emission wavelength in bioluminescence indicate that the mono-anions of firefly oxyluciferin are candidates for the light-emitters in bioluminescence. Further, we have found that the chemiluminescence of active esters of firefly luciferin produces (from the keto form of oxyluciferin) only red light emission under a variety of conditions; a yellow-green light emission (from the enolic forms of the oxyluciferin product) could not be elicited.
Analysis of Bluetooth threats and v4.0 security features (2012)

The advent of Bluetooth technology has made wireless communication easier. Any new invention or improvement is viewed very closely by people who are looking to gain information in an unauthorized manner. Security in any area is given more importance as it leads to better product and satisfied customers. The initial days of any technological invention is more challenging as they deal with new issues every day. The product/ invention needs to keep evolving to address the growing list of new features requirement and handling of security issues. Bluetooth security has evolved a lot with different versions of blue tooth. Keeping in mind the growing list of Bluetooth products in the market, there has been lot of improvements done in the version 4.0 of Bluetooth. The LE (Low Energy) operational mode which is new in version 4.0 has slightly different security association models. In this paper, a review of the recent studies in the analysis of Bluetooth security issues and new security features of v4.0 is done. Specifically the paper covers secure simple pairing in Bluetooth normal mode and low energy mode. For each threat, the particular issues are addressed and a review of major approaches to improve security of Bluetooth communication using secure simple pairing is discussed.
The effect of shade on the container index and pupal productivity of the mosquitoes <i>Aedes aegypti</i> and <i>Culex pipiens</i> breeding in artificial containers (2009)

The aim of this study was to assess whether certain attributes of larval breeding sites are correlated with pupal productivity (i.e. numbers of pupae collected per sampling period), so that these could be used as the focus for control measures to enhance control efficiency. Therefore, the objectives were to identify the months of highest pupal productivity of Aedes aegypti (L.) and Culex pipiens L. (Diptera: Culicidae) in an urban temperate cemetery in Argentina where artificial containers of < 6 L (flower vases) were the predominant breeding habitats, to compare various measures of the productivity of sunlit and shaded containers and to determine whether the composition of the containers affected pupal productivity. Over a period of 9 months, 200 randomly chosen water-filled containers (100 sunlit and 100 shaded), out of approximately 3738 containers present (approximately 54% in shade), were examined each month within a cemetery (5 ha) in Buenos Aires (October 2006 to June 2007). In total, 3440 immatures of Cx pipiens and 1974 of Ae. aegypti were collected. The larvae : pupae ratio was 10 times greater for the former, indicating that larval mortality was greater for Cx pipiens. Both mosquito species showed a higher container index (CI) in shaded than in sunlit containers (Ae. aegypti: 12.8% vs. 6.9% [chi(2) = 17.6, P < 0.001]; Cx pipiens: 6.3% vs. 1.8% [chi(2) = 24, P < 0.001]). However, the number and the density of immatures per infested container and the number of pupae per pupa-positive container did not differ significantly between sunlit and shaded containers for either species. Therefore, the overall relative productivity of pupae per ha of Ae. aegypti and Cx pipiens was 2.3 and 1.8 times greater, respectively, in shaded than in sunlit areas as a result of the greater CIs of containers in shaded areas. Neither the CI nor the number of immatures per infested container differed significantly among container types of different materials in either lighting condition. The maximum CI and total pupal counts occurred in March for Ae. aegypti and in January and February for Cx pipiens. The estimated peak abundance of pupae in the whole cemetery reached a total of approximately 4388 in the middle of March for Ae. aegypti and approximately 1059 in the middle of January for Cx pipiens. Spearman's correlations between monthly total productivity and monthly CI were significant at P < 0.001 for Ae. aegypti (r(s) = 0.975) and P < 0.01 for Cx pipiens (r(s) = 0.869). Our findings indicate that the efficacy of control campaigns against the two most important mosquito vectors in temperate Argentina could be improved by targeting containers in shaded areas, with maximum effort during species-specific times of year when pupal productivity is at its peak.