gebhart/patrepeval huggingface dataset:
Drug models of schizophrenia (2014)

Schizophrenia is a complex mental health disorder with positive, negative and cognitive symptom domains. Approximately one third of patients are resistant to currently available medication. New therapeutic targets and a better understanding of the basic biological processes that drive pathogenesis are needed in order to develop therapies that will improve quality of life for these patients. Several drugs that act on neurotransmitter systems in the brain have been suggested to model aspects of schizophrenia in animals and in man. In this paper, we selectively review findings from dopaminergic, glutamatergic, serotonergic, cannabinoid, GABA, cholinergic and kappa opioid pharmacological drug models to evaluate their similarity to schizophrenia. Understanding the interactions between these different neurotransmitter systems and their relationship with symptoms will be an important step towards building a coherent hypothesis for the pathogenesis of schizophrenia.
A surveillance of human influenza virus in swine in southern Taiwan. (1977)

From September 1970 to December 1971, samples were taken monthly from farm pigs, piglets and abattoir pigs in Southern Taiwan for virus isolations and serologic studies. A total of 10 strains of hemagglutinating agent were isolated in January and July 1971, following 2 epidemics of human influenza occurring in December 1970 and June 1971, respectively. Three strains were antigenically confirmed as influenza A similar to A/Hong Kong/68 virus.
After Acute Myocardial Infarction Hypersensitive C-reactive Protein Changes and Effects of Drugs (2010)

Objective To observe the clinical efficacy of Xuefu zhuyu granules modified for treatment of acute myocardial infarction(AMI),and markers of inflammation in hypersensitive C-Reactive protein(hs-CRP).Methods Total 64 cases that qualified as eligible patients were randomly divided into two groups: control group,32 patients given conventional treatment;treatment group 32 cases,in the conventional therapy based on the Xuefu zhuyu granules 6g,day 3 times,treatment for 2 weeks.Observed two groups patients after treatment,the fatality,incidence of cardiac ischemia-related events,and serum high-sensitivity C-reactive protein level changes.Results The incidence of ischemia-related events decreased significantly(P0.05);high-sensitivity C-reactive protein decreased significantly compared with before treatment(P0.05),compared with the control group there is significant difference(P0.05).Conclusion Modified Xuefu zhuyu granules is safe and effective treatment for acute myocardial infarction and its mechanism may be related to the decrease of serum hs-CRP levels,inhibit vascular inflammation AMI,stable plaque.
Dealing with cybersecurity threats posed by globalised IT suppliers (2013)

A multilateral process is needed to verify the integrity of globalised information technology supply chains.
Effectiveness of functional hand splinting and the cognitive orientation to occupational performance (CO-OP) approach in children with cerebral palsy and brain injury: two randomised controlled trial protocols (2014)

This paper outlines the protocol for two randomised controlled trials investigating functional hand splints and CO-OP for children with CP and BI.
A voice-operated response unit for use in the psychological assessment of motor impaired subjects (1982)

A voice-operated response unit was developed using existing microprocessing technology to enable the vocal recording of answers to a psychological test–the Minnesota Multiphasic Personality Inventory (MMPI), which cannot be completed in standard paper-and-pencil format by persons with impaired hand function. Components, cost and operation of the system are described, and data concerning reliability are presented. Applications for such a system are discussed, as are extensions of its utility to other psychological tests.
Immune evasion via PD-1/PD-L1 on NK cells and monocyte/macrophages is more prominent in Hodgkin lymphoma than DLBCL (2018)

Much focus has been on the interaction of programmed cell death ligand 1 (PD-L1) on malignant B cells with programmed cell death 1 (PD-1) on effector T cells in inhibiting antilymphoma immunity. We sought to establish the contribution of natural killer (NK) cells and inhibitory CD163<sup>+</sup> monocytes/macrophages in Hodgkin lymphoma (cHL) and diffuse large B-cell lymphoma (DLBCL). Levels of PD-1 on NK cells were elevated in cHL relative to DLBCL. Notably, CD3<sup>-</sup>CD56<sup>hi</sup>CD16<sup>-ve</sup> NK cells had substantially higher PD-1 expression relative to CD3<sup>-</sup>CD56<sup>dim</sup>CD16<sup>+</sup> cells and were expanded in blood and tissue, more marked in patients with cHL than patients with DLBCL. There was also a raised population of PD-L1-expressing CD163<sup>+</sup> monocytes that was more marked in patients with cHL compared with patients with DLBCL. The phenotype of NK cells and monocytes reverted back to normal once therapy (ABVD [doxorubicin 25 mg/m<sup>2</sup>, bleomycin 10 000 IU/m<sup>2</sup>, vinblastine 6 mg/m<sup>2</sup>, dacarbazine 375 mg/m<sup>2</sup>, all given days 1 and 15, repeated every 28 days] or R-CHOP [rituximab 375 mg/m<sup>2</sup>, cyclophosphamide 750 mg/m<sup>2</sup> IV, doxorubicin 50 mg/m<sup>2</sup> IV, vincristine 1.4 mg/m<sup>2</sup> (2 mg maximum) IV, prednisone 100 mg/day by mouth days 1-5, pegfilgrastim 6 mg subcutaneously day 4, on a 14-day cycle]) had commenced. Tumor-associated macrophages (TAMs) expressed high levels of PD-L1/PD-L2 within diseased lymph nodes. Consistent with this, CD163/PD-L1/PD-L2 gene expression was also elevated in cHL relative to DLBCL tissues. An in vitro functional model of TAM-like monocytes suppressed activation of PD-1<sup>hi</sup> NK cells, which was reversed by PD-1 blockade. In line with these findings, depletion of circulating monocytes from the blood of pretherapy patients with cHL and patients with DLBCL enhanced CD3<sup>-</sup>CD56<sup>hi</sup>CD16<sup>-ve</sup> NK-cell activation. We describe a hitherto unrecognized immune evasion strategy mediated via skewing toward an exhausted PD-1-enriched CD3<sup>-</sup>CD56<sup>hi</sup>CD16<sup>-ve</sup> NK-cell phenotype. In addition to direct inhibition of NK cells by the malignant B cell, suppression of NK cells can occur indirectly by PD-L1/PD-L2-expressing TAMs. The mechanism is more prominent in cHL than DLBCL, which may contribute to the clinical sensitivity of cHL to PD-1 blockade.
Orientation-Specific Computation in Stereoscopic Vision (2006)

The left and right eyes receive subtly different images from a visual scene. Binocular disparities of retinal image locations are correlated with variation in the depth of objects in the scene and make stereoscopic depth perception possible. Disparity stereoscopically specifies a stimulus; changing the stimulus in a way that conserves its disparity leaves the stimulus stereoscopically unchanged. Therefore, a person's ability to use stereo to see the depth separating any two objects should depend only on the disparities of the objects, which in turn depend on where the objects are, not what they are. However, I find that the disparity difference between two stimuli by itself predicts neither stereoacuity nor perceived depth. Human stereo vision is shown here to be most sensitive at detecting the relative depth of two gratings when they are parallel. Rotating one grating by as little as 10 degrees lowers sensitivity. The rotation can make a perceptible depth separation invisible, although it changes neither the relative nor absolute disparities of the gratings, only their relative orientations. The effect of relative orientation is not confined to stimuli that, like gratings, vary along one dimension or to stimuli perceived to have a dominant orientation. Rather, it is the relative orientation of the one-dimensional components of stimuli, even broadband stimuli, that matters. This limit on stereoscopic depth perception appears to be intrinsic to the visual system's computation of disparity; by taking place within orientation bands, the computation renders the coding of disparity inseparable from the coding of orientation.
The epigraphical evidence for the end of the Thirty (1997)

There is a good deal of epigraphic evidence relevant to the end of the Thirty and to the restoration period which followed, but there is no single place in which it has been collected. I do not propose to discuss it all; some of the problems are very complex. That is the case, above all, with the documents relevant to the nomothetic process which started after the fall of the Four Hundred and rumbled on until the prosecution of the scribe Nikomachos; discussion of the fragments of the ‘walls’ and possible erasures on them is likely to be indefinitely prolonged. The notorious text, IGii210, concerning rewards for non–citizens, has, in my time, acquired the new fragments identified by Daphne Hereward. It has had a good deal of attention, and there is some measure of agreement about the size of the name–lists, though not about much else; what we perhaps needed even more was new fragments of the decree itself, without which there can be no certainty about the date or nature of the awards. The parallel text, the honours for citizens, the Heroes of Phyle, got off to a sensational start with its identification by || Raubitschek, but, perhaps rather surprisingly, no new fragments have been identified since, despite careful study of all fragmentary name–lists by Don Bradeen. Those who have studied the 390s will testify how important it would be to have a complete list of those with that particular claim to the eunola of the demos.
Moral Sentiment from Adam Smith to Robert Burns (1998)

Reconstructing from the 199Os, I shall attempt to think back from the 1780s to attach Robert Bums's moral premises to a line of Scottish Enlightenment philosophy.I say attach to and not derive from, because along the way I will argue that in the famous Kilmarnock volume (Poems, Chiefly in the Scottish Dialect, 1786) Bums wrenches and exceeds the Francis Hutcheson-David Hume-Adam Smith philosophy of approbation, or judgment of the propriety of passions, where the moral agent is seen by the eyes of the community.After 1789 and the events in France, Bums enters the insurrectionary politics of a new era, though more obliquely and hesitatingly than the unknown William Blake and the infamous Thomas Paine.Now, say in 1795 when Bums versifies Paine in 'The rank is but the guinea's stamp, / The Man's the gowd for a' that,"} he is more concerned with exposing the inequities of rank in his Scottish community than with defining-also aggressively defying-a reputation as a man of correct and modest virtue.By the end of this essay I come round, if like Bums only partially, to Romanticism.Like his near-contemporary Blake, Bums in his poetry is the culmination, and surpassing, of certain eighteenth century traditions.Neo-classical satirists and Romantic singing bards: Blake and Bums are transitionally both, but also neither because their satire is no longer Augustan, and their songs are not yet individualized as lyrical ballads.
A High Stretchable and Self–Healing Silicone Rubber with Double Reversible Bonds (2019)

Abstract It is a challenge to synthesize silicone rubber with high stretchability and rapid self–healing ability without external stimuli. This article reports on a new class of self–healing poly(dimethylsiloxane)(PDMS) elastomer fabricated by introducing double reversible bonds (imine and hydrogen bonds) into silicone chains. Through reasonable structural design, the silicone rubber with high‐efficiency self‐healing ability was produced. The as–prepared PDMS elastomer films exhibited high stretchability (>4000%), good transparency (>80%) and fast self–healing efficiency (3 h at room temperature a healing efficiency of 93%). It could also be healed at low temperature (‐20 °C) and processed cyclically. In addition, we combined carbon nanotube films with this elastomer to prepare a flexible and stretchable capacitive sensor through a simple process.
Sodium bicarbonate buffer in dairy cow rations (1984)

It may improve production but doesn't replace good feeding and management
Serum amyloid A versus C-reactive protein in acute pancreatitis: Clinical value of an alternative acute-phase reactant (2000)

Objectives: The acute-phase reactant C-reactive protein (CRP) is currently the serum variable of choice for an early, accurate, and cost-effective severity assessment of acute pancreatitis in the daily clinical routine. Serum amyloid A (SAA) proteins comprise a family of apolipoproteins that constitute another major acute-phase reactant and thus could be a potential alternative to CRP assessment. In the present study we investigated the clinical usefulness of SAA determinations in acute pancreatitis using an automated immunoassay technique. Design: Cohort study, comparing patients with complicated and mild acute pancreatitis; control groups included individuals with further abdominal disorders and healthy volunteers. Setting: A collaborative study between the department of general surgery and the routine laboratory of the department of clinical chemistry/pathobiochemistry. Patients: We enrolled 66 patients with acute pancreatitis in the present study. Control groups consisted of healthy subjects (n = 30), patients with chronic pancreatitis (n = 20), patients with pancreatic carcinoma (n = 20), and patients with acute appendicitis (n = 20). Interventions: Blood samples were collected during 14 consecutive days in patients with acute pancreatitis. A single blood specimen was taken in all control groups after the diagnosis was established. Measurements and Main Results: SAA concentrations were 3 mg/L (median; range, 3-93) in healthy subjects. Although SAA and CRP both reached their maximum within 4 days after onset of symptoms in patients with acute pancreatitis, SAA concentrations rose faster above normal ranges and reached 676 mg/L (median; range, 12-1880), higher than CRP, which reached 313 mg/L (median; range, 29-613). As observed for CRP, SAA was significantly higher in patients who developed complications such as necrosis, infection of necrosis, or multiple organ dysfunction syndrome or in patients who died. SAA achieved best results in discriminating between necrotizing pancreatitis and interstitial edematous pancreatitis. However, CRP provided an earlier differentiation between both entities and a significantly better overall accuracy, as shown by receiver operating characteristics analysis. SAA concentrations in patients with chronic pancreatitis were 6 mg/L (median; range, 3-756). In patients with pancreatic carcinoma, SAA concentrations were 7 mg/L (median; range, 3-492), and in patients with acute appendicitis, they were 50 mg/L (median; range, 3-2140). Conclusion: SAA is a nonspecific and rapidly produced variable in inflammatory abdominal disorders with a wider dynamic range than CRP. The current assay technique renders SAA an applicable and readily available variable under clinical routine conditions. In cases of acute pancreatitis, however, CRP is still superior to SAA for early and accurate stratification of patients with a complicated course.
Further studies on acclimatization to low temperatures in the grain weevils <i>Sitophilus oryzae</i> (L.) and <i>Sitophilus granarius</i> (L.) (1980)

Abstract The effect of thermal acclimatization on the resting metabolism of adult grain weevils was examined by closely restraining the weevils during respirometry. Sitophilus oryzae (L.) acclimatized to 15°C consumed less oxygen over 11–23°C than 27°C‐acclimatized weevils but like amounts over 25–35°C. Similar results were observed with S. granarius (L.). Respiration R–T curves of unrestrained S. oryzae and S. granarius showed no evidence of rotation at temperatures close to their chill‐coma thresholds but warm‐ and cold‐acclimatized weevils consumed similar amounts of oxygen when both categories of weevils were in chillcoma. Acclimatizing S. oryzae from 27 to 13.5°C through four, weekly 4.5°C step‐transfers lowered the median chill‐coma thresholds of the weevils from 8.9 to 6.2°C, increased their life span at 9°C, an unfavourable temperature for this species, from 2 to 8 weeks and lowered their oxygen uptake at 9°C by 19%.
Durability of light steel framing in residential applications (2010)

This paper presents a summary and analysis of research findings on the durability of galvanised cold-formed steel sections used in housing in order to deduce their design life. These cold-formed sections are produced from pre-galvanised strip steel. It reviews reports and publications from research projects carried out by Corus and the Steel Construction Institute on zinc-coated, cold-formed steel products. New data have also been gathered from measurements on houses and similar buildings that have used galvanised steel components. The data also extend to over-cladding applications in building renovation. The performance of galvanised (zinc-coated) steel components within warm-frame applications is very good. The research leading to this paper shows that the predicted design life of the standard G275 coating, based on the measured loss of zinc from the strip steel, is over 200 years, provided that the building envelope is well insulated and properly maintained. The evidence for this conclusion is based on measurement of zinc loss on light steel frames in various applications and locations. A formula for the loss of zinc over time in areas subject to low condensation risk is presented.
Fabrication and characterization of a new EEPROM cell with spacer select transistor (2005)

Process technology and cell characteristics of a newly developed compact electrically erasable programmable read only memory cell are described. The cell has spacer select gates on both side walls of floating gate and this gives a very small cell size as well as relief of topology during contact formation. The cell size is 0.95 μm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> with 0.18 μm logic process. The cells are programmed and erased by Fowler-Nordheim tunneling. It appears that programming requires 3 ms at 16 V while erasing requires 2 ms at 14 V. It is shown that the cells have very uniform distribution of both programmed and erased threshold voltage. It is also shown that the cell endures up to half million cycling tests.
STUDIES ON THE VOMITING CENTER. THE LOCATION OF THE RETCHING POINTS IN THE MEDULLA AND PONS (1966)

During the experiments on the motor center of the stomach in the medulla and pons, the different types of the emetic action were observed in the dog. The monopolar tungsten wire (diameter 25 microns) was used for the stimulating electrode. The stimulated areas were determined by the histolo-gical examination.1. The retching was followed by the change of the systemic blood pressure (rise or fall) and the increase or decrease of the movements of the stomach and distal colon, but the correlation between the retching and the other autonomic reactions was not determined.2. The retching was induced in the vagotomized dog and in the spinal dog which was transected between the cervical and the thoracic region.3. The retching was induced both in the anesthetized dog and non-anesthetized dog.4. Fourty-five retching points were obtained in the medulla oblongata. They were found in the Nucl. dorsolateralis n. vagi, Nucl. dorsomedialis n. vagi, Nucl. tractus solitarii medialis, -inferior, -lateralis, Tractus solitarius, Formatia reticularis, Fibrae arcuatae internae and Nucl. intercalatus.5. Only three retching points were obtained in the pons. They were found in the Nucl. vestibularislateralis, Tractus rubrospinalis and Fibrae n. vagi.
Effects of preferred orientation on the grain size dependence of yield strength in metals (1963)

Abstract The Petch equation ([sgrave] = [sgrave]0 + kl −½) is applied rather widely in investigations of the sources of the variation of yield stress [sgrave] with grain diameter l in polycrystalline metals. In general, however, the behaviour of randomly oriented aggregates has been considered, so that [sgrave]0 and k are regarded as constant for a particular material. A preferred orientation of the crystals can influence both [sgrave]0 and k by altering the relationship between the applied stress and the shear stresses developed on active slip planes. Because k is affected by local orientation effects, it can change independently of [sgrave]0 if there is an alteration in the orientation relationships of adjacent grains. These effects of orientation will be particularly important in non-cubic metals, due to the small number of their slip systems. In magnesium extrusions considerable variations in [sgrave]0 and k were obtained by changing the direction of the applied stress relative to the extrusion axis and by changing the character of the preferred orientation.
REVIEWS (1970)

REVIEWS Get access Exile and Restoration: A Study of Hebrew Thought of the Sixth Century B.C. By PETER R. ACKROYD. Pp. xv + 286. (Old Testament Library.) London: S.C.M. Press, 1968. 55s. JOHN BAKER JOHN BAKER Search for other works by this author on: Oxford Academic Google Scholar The Journal of Theological Studies, Volume XXI, Issue 1, April 1970, Pages 142–145, https://doi.org/10.1093/jts/XXI.1.142 Published: 01 April 1970
Einleitung (1990)

In diesem Buch werden unter dem Begriff „Flugzeuge“ solche fliegende Geräte verstanden, die von Menschen erbaut worden sind und die „schwerer als Luft“ sind. Luftschiffe und Ballone sollen also ausgeschlossen sein, ebenso fliegende Tiere und Pflanzen. Dagegen muß ein solches Flugzeug nicht unbedingt einen Menschen tragen können. Unter die Kategorie „Flugzeug“ sollen also so verschiedene Dinge fallen wie: Flugmodelle, Hängegleiter, Sportflugzeuge, Verkehrsflugzeuge und Überschallflugzeuge.
Data Security Equals Graph Connectivity (1996)

To protect sensitive information in a cross-tabulated table, it is a common practice to suppress some of the cells in the table. This paper investigates four levels of data security of a two-dimensional table concerning the effectiveness of this practice. These four levels of data security protect the information contained in, respectively, individual cells, individual rows and columns, several rows or columns as a whole, and a table as a whole. The paper presents efficient algorithms and NP-completeness results for testing and achieving these four levels of data security. All these complexity results are obtained by means of fundamental equivalences between the four levels of data security of a table and four types of connectivity of a graph constructed from that table.
Fast Handoff for Hierarchical Mobile SIP Networks (2005)

Although it was originally developed as an application layer signalling protocol, SIP offers mobility management capability. However SIP Terminal Mobility suffers from considerable handoff latency which is unsuitable for real time applications and frequent local movements (intra domain handoffs). Hierarchical Mobile SIP (HMSIP) was then proposed as a solution to reduce the SIP handoff delay and to provide a complete micro-mobility solution for SIP environments. Unfortunately HMSIP handoff delays remain too high for real time multimedia applications which require handoff delay between 50ms and 200ms to guarantee the Quality of Service. In this paper we propose to reinforce the HMSIP by integrating the Predictive Address Reservation (PAR) mechanism to get better handoff performance. A simple integration of PAR-SIP with HMSIP allows not only reducing handoff delay but also signaling overhead. Keywords—Fast handoff, Multimedia applications QoS, SIP Mobility management, Wireless communication.