gebhart/patrepeval huggingface dataset:
Viscoelastic Response of Photo-Cross-Linked Poly(<i>N</i>-isopropylacrylamide) Coatings by QCM-D (2009)

The viscoelastic behavior of surface-tethered poly(N-isopropylacrylamide), or poly(NIPAAm), networks in contact with aqueous solutions was characterized by the quartz crystal microbalance with dissipation (QCM-D). To avoid ambiguities in the data analysis, four integer multiples of the dry thickness (h = k x 36 nm, where k = 1, 2, 3, 4) were analyzed at the third through ninth overtones of the QCM-D signal. At the third overtone, the networks resembled rigid films and the viscoelastic behavior could not be ascertained. With increasing overtones, however, the films showed deviation from the rigid film limit, allowing for analysis of the viscoelastic parameters. As the network collapsed over the temperature range of 15-40 degrees C, the shear modulus of the network increased by a factor of 24 (from 5 to 120 MPa); the shear viscosity, on the other hand, increased only by a factor of 2 (from 40 to 80 cP). The high values of the shear modulus suggest the QCM-D probes a regime where the polymer mesh does not adequately relax, and the high values of the shear viscosity suggest significant polymer-polymer coil overlap above and below the demixing temperature. Finally, the influence of NaCl on the viscoelastic response was measured. Interestingly, NaCl affects the shear modulus of the networks but not the dynamics.
Evolutionary Processes among Sylvatic Dengue Type 2 Viruses (2007)

Sylvatic dengue viruses (DENV) are transmitted in an enzootic cycle between nonhuman primates and arboreal Aedes mosquitoes in Southeast Asia and West Africa. Although previous analyses have revealed the evolutionary processes among endemic (human) DENV, little is known about viral evolution in the sylvatic cycle. Through an analysis of 14 complete coding regions of sylvatic Dengue type 2 virus sampled over a 33-year period, we show that both the rate of evolutionary change and the pattern of natural selection are similar among endemic and sylvatic DENV, although the latter have a uniquely high frequency of positive selection in the NS4B protein gene. Our findings support a recent cross-species transmission event and suggest the possibility of future DENV reemergence from the sylvatic cycle.
Heat treatment and CVD aluminizing of Ni-base René 80 superalloy (2012)

Purpose: This work presents the results of microstructure investigations which were carried out on Ni-base Rene 80 polycrystalline superalloy. Design/methodology/approach: Polycrystalline cast rods have been used in the studies. The heat treatment processes were conducted in ALD High Temperature Vacuum Furnace at 1204°C for 2 h, in Ar atmosphere followed by cooling to room temperature. The aluminizing processes were conducted by use of CVD method on as cast samples and after homogenizing-solution annealing. The diffusion low activity aluminide coatings have been produced using the CVD IonBond BPXPR0325S apparatus at various temperatures, for 4 h and applying different values of: flow rate of HCl through the outer AlCl3 generator and pressure in main retort in H2 atmosphere. The microstructure investigations were conducted using scanning electron microscope. To the purpose of analysis of the chemical composition an X-ray microanalysis technique was applied with the dispersion of the energy (EDS) using of Thermo and Noran equipment. Findings: It was found that samples without heat treatment had the typical cast microstructure with many areas of the ��–��’ eutectic, after heat treatment process the microstructure wa
An incremental capacitive sensor for harsh environment (2003)

This paper presents a new approach for the design of incremental angular position and angular speed sensors, using a capacitive technology. Transmitter and receiver segments are integrated with the sensor electronics on a single PCB. As the sensor measures the change of capacitance in dependence of the rotor position, any conductive or dielectric material can be used for the gear-tooth rotor. The carrier frequency excitation and the differential sensor output assure a high level of EMC.
BREEDING AND GENETICS Estimating Seed Surface Area of Cottonseed (2010)

Seed surface area (SSA) may be estimated by WinSeedle Image Analysis System, transformations of seed volume (Hodson method) or by seed index. If fuzzy seed index were related to SSA, SSA could be estimated without delinting seed. Our objective was to compare different methods of estimating SSA using fuzzy, acid- and flame-delinted seed. Seed were produced at two Arkansas locations and included eight diverse genotypes. After ginning, 100-fuzzy seed samples from a total of 10 replicates of field plots were randomly selected and weighed. Samples were flame-delinted, and then weighed, volume displacement determined, and scanned by digital analysis. The same seeds were then acid-delinted, weighed and SSA recalculated in the same manner. Location by genotype and genotype by delinting method interactions were significant for seed index, Hodson SSA and WinSeedle SSA. Volume means were significant for all main effects. Variation among genotypes was relatively similar for each parameter. Lowest correlations were found associated with volume of flame-delinted seed. Otherwise, seed index of fuzzy and acid-delinted seed were highly correlated with seed volume and both SSA measurements. Fuzzy seed index explained more variation in WinSeedle SSA than any other parameter. A regression equation may be used to transform fuzzy seed index to estimated SSA. The strong relationships of fuzzy seed index to delinted seed index, seed volume and the WinSeedle SSA measurements indicate that it can be used as an indicator of SSA when estimating fiber density.
Cloud-based tasking, collection, processing, exploitation, and dissemination (2013)

The current explosion in sensor data has brought us to a tipping point in the intelligence, surveillance, and reconnaissance technologies. This problem can be addressed through the insertion of novel artificial intelligence-based methodologies. The scope of the problem addressed in this position paper is to propose a novel computational intelligence methodology, which can learn to map distributed heterogeneous data to actionable meaning for dissemination. The impact of this approach is that it will provide a core solution to the tasking, collection, processing, exploitation, and dissemination (TCPED) problem. It will serve to demonstrate the viability of the methodologies core concepts and thus justify a scaled-up investment in its development. Consequently, the expected operational performance improvements include the capture and reuse of analyst expertise, an order of magnitude reduction in required bandwidth, and, for the user, prioritized intelligence based on the knowledge derived from distributed heterogeneous sensing.
The first super-Earth detection from the high cadence and high radial velocity precision Dharma Planet Survey (2018)

The Dharma Planet Survey (DPS) aims to monitor about 150 nearby very bright FGKM dwarfs (within 50 pc) during 2016$-$2020 for low-mass planet detection and characterization using the TOU very high resolution optical spectrograph (R$\approx$100,000, 380-900nm). TOU was initially mounted to the 2-m Automatic Spectroscopic Telescope at Fairborn Observatory in 2013-2015 to conduct a pilot survey, then moved to the dedicated 50-inch automatic telescope on Mt. Lemmon in 2016 to launch the survey. Here we report the first planet detection from DPS, a super-Earth candidate orbiting a bright K dwarf star, HD 26965. It is the second brightest star ($V=4.4$ mag) on the sky with a super-Earth candidate. The planet candidate has a mass of 8.47$\pm0.47M_{\rm Earth}$, period of $42.38\pm0.01$ d, and eccentricity of $0.04^{+0.05}_{-0.03}$. This RV signal was independently detected by Diaz et al. (2018), but they could not confirm if the signal is from a planet or from stellar activity. The orbital period of the planet is close to the rotation period of the star (39$-$44.5 d) measured from stellar activity indicators. Our high precision photometric campaign and line bisector analysis of this star do not find any significant variations at the orbital period. Stellar RV jitters modeled from star spots and convection inhibition are also not strong enough to explain the RV signal detected. After further comparing RV data from the star's active magnetic phase and quiet magnetic phase, we conclude that the RV signal is due to planetary-reflex motion and not stellar activity.
Nonvascularized Bone Grafts for Osteonecrosis of the Femoral Head: Current Concepts and Techniques (2001)

For the past 30 years, nonvascularized bone grafts have been used in the treatment of osteonecrosis of the femoral head. Originally, various tibial, fibular, or iliac crest grafts were introduced through a core track into the femoral head. These produced less than optimal long-term results. More recently, various grafts have been used through windows made in the femoral neck or head to more directly replace the dead bone and support the collapsing segment. Results of these recent techniques are promising and may be further improved in the future by pharmacologic agents that enhance bone healing.
Cooperative retransmissions using Markov decision process with reinforcement learning (2009)

In cooperative retransmissions, nodes with better channel qualities help other nodes in retransmitting a failed packet to its intended destination. In this paper, we propose a cooperative retransmission scheme where each node makes local decision to cooperate or not to cooperate at what transmission power using a Markov decision process with reinforcement learning. With the reinforcement learning, the proposed scheme avoids solving an Markov decision process with a large number of states. Through simulations, we show that the proposed scheme is robust to collisions, is scalable with regard to the network size, and can provide significant cooperative diversity.
An examination of the soluble oligomeric complexes extracted from the red cell membrane and their relation to the membrane cytoskeleton. (1985)

A part of the spectrin extracted from red cell membranes at low ionic strength occurs in the form of a high-molecular weight oligomeric complex with actin and proteins 4.1 and 4.9. When the extraction is performed at 35 degrees, the spectrin is present in this complex as the dimer, all higher forms being dissociated. We have been unable to establish any correlation between the fraction of the spectrin thus complexed and the metabolic state of the cell. At least a large part of the complex appears to be a defined monodisperse species, sedimenting at 31S. The actin is present as short protofilaments. The average number of spectrin molecules associated with each molecule of complex has been studied by cytochalasin binding and electron microscopy. The complexes present the appearance in the electron microscope of spiders, in which the legs are spectrin dimers, attached to a globular element, containing by inference, actin and proteins 4.1 and 4.9; they are active in nucleating the polymerization of G-actin. The complexes are extremely stable, being resistant to dissociation under the conditions of the deoxyribonuclease assay, even after treatment with trypsin to degrade the actin-associated proteins. It is suggested that the complexes represent intact junctions of the membrane cytoskeletal network. Relevant structural features of the network are revealed by electron microscopy. The results lead to inferences concerning the mechanism of dissociation of the network from the membrane.
EFFECTS OF EXERCISE INTENSITY ON SERUM LEPTIN LEVELS (1998)

1047 Leptin, the product of the ob gene, is related to body fat content in humans. Recent data suggest that exercise training lowers serum leptin levels. Whether this is related to the acute or chronic effects of exercise, independent of weight loss, has not been determined. We investigated the effects of exercise intensity on serum leptin levels. Seven male subjects(age = 25.5 yr; ht = 177.5 cm; wt = 80.5 kg; VO2 LT = 36.3 ml·kg·min-1, VO2 peak = 49.5 ml·kg·min-1,% body fat = 19.3) were tested on six occasions [control (C), 5 exercise conditions (EX) 30 min at the following intensities: 25 and 75% of the Δ between LT and rest (0.25 LT, 0.75 LT), at LT, and at 25 and 75% of the Δ between LT and peak (1.25 LT, 1.75 LT)]. Subjects were admitted to the GCRC at 2000h, fed a standardized snack and then fasted until the end of the admission. From 0700h to 1300h blood was sampled at 10 min intervals and assayed for serum leptin using a sensitive radioimmunoassay. During C and before and after EX subjects rested quietly in their rooms. Leptin area under the curve (AUC) was calculated for baseline(0700-0900h) and for exercise + recovery (0900-1300h). Results [mean (SEM)] are presented below: TableTableANOVA with repeated measures revealed no differences for leptin AUC among conditions within either the baseline or exercise + recovery time frames. Examination of the mean serum leptin concentrations on a 10 min by 10 min basis did not reveal any changes across conditions or over time. We conclude that 30 min of acute exercise at varying intensities does not affect serum leptin concentration.
Pyrrolidone Carboxyl Peptidase from the Hyperthermophilic Archaeon Pyrococcus furiosus: Cloning and Overexpression in Escherichia coli of the Gene, and Its Application to Protein Sequence Analysis (1998)

A gene for a pyrrolidone carboxyl peptidase (Pcp: EC 3.4.19.3, pyroglutamyl peptidase), which removes amino-terminal pyroglutamyl residues from peptides and proteins, has been cloned from the hyperthermophilic Archaeon Pyrococcus furiosus using its cosmid protein library, sequenced, and expressed in Escherichia coli. The DNA sequence encodes a protein containing 208 amino acid residues with methionine at the N-terminus. Analysis of the recombinant protein expressed in E. coli, including amino acid sequence analysis from the N-terminus by automated Edman degradation and ionspray mass spectrometric analysis of the peptides generated by enzymatic digestions with lysylendopeptidase and Staphylococcus aureus V8 protease, showed its primary structure to be completely identical with that deduced from its cDNA sequence. Comparison of the amino acid sequence of P. furiosus Pcp (P.f.Pcp) with those of bacterial Pcps revealed that a high degree of sequence identity (more than 40%) and conservation of the amino acid residues comprising the catalytic triad, Cys142, His166, and Glu79. On the other hand, a unique short stretch sequence (positions around 175-185) that is absent in bacterial Pcps was found in P.f.Pcp. A similar stretch has also been reported recently in the amino acid sequence of Pcp from the hyperthermophilic Archaeon Thermococcus litoralis [Littlechild et al., in abstracts of the "International Congress on Exthermophiles '98" p. 58 (1998)]. To elucidate their contribution to the hyperthermostability of these enzymes, further structural studies are required.
Proposal and examination of new type of TFT with tunneling dielectric film at both ends of channel fabrication area (2005)

Abstract An important aspect of a thin‐film transistor (TFT) is reducing the current flowing between the source and drain when the gate is off. In this research, we proposed a new TFT, the tunneling dielectric TFT (TDTFT), that has a thin dielectric film on both ends of the channel region, and studied its operation through simulations. We calculated the drain current ( I off ) when the gate is off, the drain current–drain voltage characteristic, and the transconductance in the TDTFT. When the thin dielectric film is a 0.5‐nm‐thick TiO 2 film, I off of the TDTFT is about six digits less than that of a conventional TFT. We also studied the double silicon on insulator (DSOI) structure which improves the drive power of the TFT even for a thin Si film. When a TDTFT is fabricated on DSOI, simple calculations showed that the on–off ratio was several times better than that of a conventional TFT. © 2005 Wiley Periodicals, Inc. Electron Comm Jpn Pt 2, 88(11): 44–53, 2005; Published online in Wiley InterScience ( www.interscience.wiley.com ). DOI 10.1002/ecjb.10210
Sous la direction de M. J. Brunhes Delamare, P. Deffontaines, A. Journaux, Géographie régionale (1978)

Fischer André. Sous la direction de M. J. Brunhes Delamare, P. Deffontaines, A. Journaux, Géographie régionale . In: Annales de Géographie, t. 87, n°483, 1978. pp. 582-583.
Use of quantitative real-time PCR for studying the dissemination of Leptospira interrogans in the guinea pig infection model of leptospirosis (2009)

The dynamics of leptospirosis infection have been poorly studied. The purpose of this study was to determine the LD(50), rate of bacterial dissemination, histopathology and antibody responses against leptospira following inoculation with the highly virulent Leptospira interrogans Fiocruz L1-130 strain in a guinea pig model of leptospirosis. Three routes of infection (intraperitoneal, conjunctival and subcutaneous inoculation) were used to establish disease in guinea pigs. The size and kinetics of leptospiral burdens in the blood and tissues of infected animals were determined over a 1 week course of infection using quantitative real-time PCR (qPCR). Bacteraemia peaked at day 5 post-infection reaching more than 5x10(4) leptospires ml(-1). The highest spirochaetal load was found in the liver and kidneys, and was associated with alterations in organ tissues and a decline in liver and kidney functions. In contrast, lesions and bacteria were not detected in guinea pigs infected with an avirulent strain derived from a high-passage-number in vitro-passaged variant of the Fiocruz L1-130 strain. The use of qPCR supports the findings of earlier studies and provides an easy and reliable method for the quantification of L. interrogans in the tissues of infected animals. qPCR will be used in future studies to evaluate the efficacy of vaccine candidates against leptospirosis and the virulence of selected L. interrogans mutants relative to the parental strain.
Phase II clinical evaluation of intravenous 4′-(9-acridinylamino) methanesulfon-m-anisidide in colorectal cancer (1983)

Thirty-five patients with measurable metastatic colorectal cancer received 4'-(9-acridinylamino)methanesulfon-m-anisidide (AMSA) on a 3-day intravenous schedule repeated every 3 weeks. There were 17 previously untreated patients and 18 patients who had disease progression on several regimens containing 5-fluorouracil. Good-risk patients received an initial daily AMSA dose of 40 mg/m2; poor-risk patients received an initial daily dose of 30 mg/m2. There were no complete or partial remissions. Ten patients achieved disease stabilization, 24 had disease progression and one patient was lost to follow-up. The most common toxicity associated with AMSA therapy was myelosuppression, with a greater effect on neutrophils than platelets. Median (range) lowest neutrophils and platelet counts X 10(3)/mm3 were 1.2 (0-5.0) and 209 (50-413), respectively. Myelosuppression was pronounced in patients with abnormalities of liver function. Other toxicities were negligible, although one patient developed an episode of cardiac arrhythmia which may have been secondary to AMSA therapy.
Loss of neutral endopeptidase (NEP) activity contributes to neutrophil oxidative activation during Mg‐deficiency (2010)

NEP, a cell‐surface proteolytic enzyme, degrades substance P (SP). The effect of Mg‐deficiency on neutrophil NEP activity and cell activation were examined. Male SD rats (180g) were fed Mg‐sufficient (MgS) or ‐deficient (MgD, 9% RDA) diets for 5 wks. Enriched blood neutrophils were isolated at the end of 1, 3, 5 wks by step gradient centrifugation. NEP activity (by a fluorimetric method) decreased 15% (NS), 50% (p<0.025) and 57% (p<0.01) respectively for wks 1, 3, and 5 MgD rats. In association, neutrophil basal superoxide (·O2‐) generating activities were elevated, 33% at wk 1 (NS), 5–7 fold for wks 3, 5 (p<0.01) above MgS controls. The maximally stimulated (by PMA) ·O2‐ production increased 2‐fold from 5 wk MgD neutrophils. Also, plasma 8‐isoprostane levels were elevated 2–3‐fold and RBC GSH decreased 50% (p<0.01) during 3–5 wks of MgD. Plasma SP levels were elevated 5‐fold in wk 1 and 9–10‐fold (p<0.01) in 3–5 wks. When MgD rats were treated with a SP receptor blocker, L703,606 (1mg/kg/day s.c.), NEP activities were 75% (wk 3) and 77% (wk 5) preserved (p<0.05) comparing to MgS neutrophils; activation of neutrophil ·O2‐ and other oxidative indices were also significantly (p<0.05) attenuated. Since SP receptors are present on neutrophils, we conclude that NEP activity regulates neutrophil ·O2‐ formation by controlling SP availability; in turn, oxidative inactivation of NEP is prevented by SP receptor blockade. (Supported by NIH‐HL‐62282, HL‐65178)
Zur Revision des FPI. Weitere Analysen und ergänzende Tabellen zur 4.Aufl. des Freiburger Persönlichkeitsinventars (1984)

Anlässlich der 4. Auflage des Freiburger Persönlichkeitsinventars wurde durch das Institut für Demoskopie, Allensbach, eine Repräsentativerhebung an N = 2035 Personen vorgenommen. Dieser Datensatz diente (1) zur neuen Normierung der Form A des FPI (FPI-A) und (2) zur Konstruktion eines revidierten, hinsichtlich der Skalen erweiterten und hinsichtlich der Items gekürzten Persönlichkeitsinventars (FPI-R). Die Strategien und Ergebnisse dieser Revision sind in der 4. Auflage der Handanweisung (Fahrenberg, Hampel & Selg, 1984) beschrieben. Dieser zusätzliche Forschungsberichtsoll weiteres Tabellenmaterial, das nicht in die Handanweisung aufgenommen werden konnte, und die Itempools der beiden Prätests und der Repräsentativerhebung dokumentieren.
3-D nonlinear calculations of resistive tearing modes (1981)

Recent numerical calculations of the evolution of resistive tearing modes have been central to the understanding of magnetohydrodynamic activity and disruptions in tokamaks. The nonlinear, 3-D, initial-value computer code RSF has provided many of these results. This code assumes cylindrical geometry with a Fourier series representation in the two periodic coordinates and a finite-difference representation in the radial direction. This choice makes RSF considerably more accurate and efficient than previous codes.
Evidence for functional interaction between domains II and V of 23S ribosomal RNA from an erythromycin-resistant mutant. (1985)

A mutation affording low levels of erythromycin resistance has been obtained by in vitro hydroxylamine mutagenesis of a cloned ribosomal RNA operon from Escherichia coli. The site of the mutational event responsible for antibiotic resistance was localized to the gene region encoding domain II of 23S rRNA by replacement of restriction fragments in the wild-type plasmid by corresponding fragments from the mutant plasmid. DNA sequencing showed that positions 1219-1230 of the 23S rRNA gene are deleted in the mutant. Since all previously characterized rRNA mutations conferring resistance to erythromycin show changes exclusively in domain V, our present findings provide direct evidence for functional interaction between domains II and V of 23S rRNA.
Synthesis of isopentabromopseudilin (1991)

Abstract Isopentabromopseudilin ( 4 ) and the analogous compounds 12g, 12h have been synthesized by base‐catalyzed cyclization of substituted benzaldehydes with isocyanoacetic acid methyl ester ( 6 ). In contrast to the highly antibiotic and cytotoxic active natural product 1 , compounds 4, 12g and 12h have been shown to be inactive.