gebhart/patrepeval huggingface dataset:
ChemInform Abstract: Rational Design, Green Synthesis, and Initial Evaluation of a Series of Full‐Color Tunable Fluorescent Dyes Enabled by the Copper‐Catalyzed N‐Arylation of 6‐Phenyl Pyridazinones and Their Application in Cell Imaging. (2014)

ChemInformVolume 45, Issue 10 Heterocyclic Compounds ChemInform Abstract: Rational Design, Green Synthesis, and Initial Evaluation of a Series of Full-Color Tunable Fluorescent Dyes Enabled by the Copper-Catalyzed N-Arylation of 6-Phenyl Pyridazinones and Their Application in Cell Imaging. Lei Liang, Lei Liang Dep. Med. Chem., Sch. Pharm. Sci., Peking Univ., Beijing 100083, Peop. Rep. ChinaSearch for more papers by this authorWei Wang, Wei Wang Dep. Med. Chem., Sch. Pharm. Sci., Peking Univ., Beijing 100083, Peop. Rep. ChinaSearch for more papers by this authorJun Wu, Jun Wu Dep. Med. Chem., Sch. Pharm. Sci., Peking Univ., Beijing 100083, Peop. Rep. ChinaSearch for more papers by this authorFengrong Xu, Fengrong Xu Dep. Med. Chem., Sch. Pharm. Sci., Peking Univ., Beijing 100083, Peop. Rep. ChinaSearch for more papers by this authorYan Niu, Yan Niu Dep. Med. Chem., Sch. Pharm. Sci., Peking Univ., Beijing 100083, Peop. Rep. ChinaSearch for more papers by this authorBo Xu, Bo Xu Dep. Med. Chem., Sch. Pharm. Sci., Peking Univ., Beijing 100083, Peop. Rep. ChinaSearch for more papers by this authorPing Xu, Ping Xu Dep. Med. Chem., Sch. Pharm. Sci., Peking Univ., Beijing 100083, Peop. Rep. ChinaSearch for more papers by this author Lei Liang, Lei Liang Dep. Med. Chem., Sch. Pharm. Sci., Peking Univ., Beijing 100083, Peop. Rep. ChinaSearch for more papers by this authorWei Wang, Wei Wang Dep. Med. Chem., Sch. Pharm. Sci., Peking Univ., Beijing 100083, Peop. Rep. ChinaSearch for more papers by this authorJun Wu, Jun Wu Dep. Med. Chem., Sch. Pharm. Sci., Peking Univ., Beijing 100083, Peop. Rep. ChinaSearch for more papers by this authorFengrong Xu, Fengrong Xu Dep. Med. Chem., Sch. Pharm. Sci., Peking Univ., Beijing 100083, Peop. Rep. ChinaSearch for more papers by this authorYan Niu, Yan Niu Dep. Med. Chem., Sch. Pharm. Sci., Peking Univ., Beijing 100083, Peop. Rep. ChinaSearch for more papers by this authorBo Xu, Bo Xu Dep. Med. Chem., Sch. Pharm. Sci., Peking Univ., Beijing 100083, Peop. Rep. ChinaSearch for more papers by this authorPing Xu, Ping Xu Dep. Med. Chem., Sch. Pharm. Sci., Peking Univ., Beijing 100083, Peop. Rep. ChinaSearch for more papers by this author First published: 21 February 2014 https://doi.org/10.1002/chin.201410181Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat No abstract is available for this article. Volume45, Issue10March 11, 2014 RelatedInformation
Bioactive Peptides in Amaranth (<i>Amaranthus hypochondriacus</i>) Seed (2008)

Amaranth seeds are rich in protein with a high nutritional value, but little is known about their bioactive compounds that could benefit health. The objectives of this research were to investigate the presence, characterization, and the anticarcinogenic properties of the peptide lunasin in amaranth seeds. Furthermore, to predict and identify other peptides in amaranth seed with potential biological activities. ELISA showed an average concentration of 11.1 microg lunasin equivalent/g total extracted protein in four genotypes of mature amaranth seeds. Glutelin fraction had the highest lunasin concentration (3.0 microg/g). Lunasin was also identified in albumin, prolamin and globulin amaranth protein fractions and even in popped amaranth seeds. Western blot analysis revealed a band at 18.5 kDa, and MALDI-TOF analysis showed that this peptide matched more than 60% of the soybean lunasin peptide sequence. Glutelin extracts digested with trypsin, showed the induction of apoptosis against HeLa cells. Prediction of other bioactive peptides in amaranth globulins and glutelins were mainly antihypertensive. This is the first study that reports the presence of a lunasin-like peptide and other potentially bioactive peptides in amaranth protein fractions.
Noise and synchronization in chaotic systems (1996)

We investigate the behavior of several noisy nonlinear dynamical models in order to find out whether the presence of a common noise term may synchronize identical chaotic systems as recently supposed [S. Fahy and D. R. Hamann, Phys. Rev. Lett. 69, 761 (1993); A. Maritan and J. R. Banavar, ibid. 72, 1451 (1994)]. The results of the present study show that noise can speed up orbit convergence in a restricted context, but in general cannot drive, by itself, a transition from chaotic to nonchaotic behavior. \textcopyright{} 1996 The American Physical Society.
On dual lattice attacks against small-secret LWE and parameter choices in HElib and SEAL. (2017)

We present novel variants of the dual-lattice attack against LWE in the presence of an unusually short secret. These variants are informed by recent progress in BKW-style algorithms for solving LWE. Applying them to parameter sets suggested by the homomorphic encryption libraries HElib and SEAL yields revised security estimates. Our techniques scale the exponent of the dual-lattice attack by a factor of \((2\,L)/(2\,L+1)\) when \(\log q = \varTheta {\left( L \log n\right) }\), when the secret has constant hamming weight \(h\) and where \(L\) is the maximum depth of supported circuits. They also allow to half the dimension of the lattice under consideration at a multiplicative cost of \(2^{h}\) operations. Moreover, our techniques yield revised concrete security estimates. For example, both libraries promise 80 bits of security for LWE instances with \(n=1024\) and \(\log _2 q \approx {47}\), while the techniques described in this work lead to estimated costs of 68 bits (SEAL) and 62 bits (HElib).
P06.03: Fetal tachyarrhythmia: diagnosis, treatment and outcome (2016)

Fetal arrhythmias are detected in 2% of pregnancies during routine obstetrical scans. Almost are transient or premature atrial contractions (PAC) without hemodynamic repercussion. But, the correct prenatal diagnosis and treatment of malignant arrhythmias is a challenge for experts. The aim of our study was to describe the experience of our group in fetal tachyarrhythmia and its outcome. The group of 1821 pregnant women was prospectively examined from June 2011 to March 2016. The patients were divided into PAC and fetal tachycardia (HR>180 bpm). The study included 180 fetuses at 17–40 weeks of GA. The most common was PAC (100/180, 55,5%). There were 12 (0,7%) fetuses with bi or trigeminism, 33 (18,3%) sinusal tachycardia, 28 (15,6%) supraventricular tachycardia (SVT) and 7 (0,4%) atrial flutter (AF). Hydrops fetalis was reported in 12 fetuses 8 with SVT and 4 with AF, respectively. Those with bi or trigeminism did not have hydrops and 7 needed treatment. Digoxin treatment resulted in a higher conversion rate in non-hydropic fetuses. In 13 cases (6 AF) it was necessary a combination of 2 or 3 antiarrhythmic drugs (sotalol and/or propafenone). The 133 fetus with benign arrhythmias (PAC < 11/mi and sinusal tachycardia) did not need any treatment before or after birth. 18 newborns (12 SVT and 6 AF) presented hemodynamic repercussion and needed treatment. No one died, but there were 22 preterm infants. GA at birth ranged from 34 to 40 weeks. Ten premature births were due to mother's diseases and 12 due to fetal hydrops with SVT or AF. Most arrhythmias are benign, but supraventricular tachycardia and atrial flutter could be dangerous and require treatment. In cases without hydrops a single digoxin therapy is successful, but hydropic fetuses may require more medication and a longer treatment period. The continuous surveillance is important and in almost all cases the treatment is successful improving outcome.
Some Investigations into the Application of Dyes to Acrylic Fibres (1957)

The chief characteristics of polyacrylonitrile fibres are described briefly. Methods of application of disperse, basic (including Perkin's Mauve), Deorlene, acid, metal‐complex, and chrome dyes to acrylic fibres, particularly Orion 42 and Acrilan, are given in detail, and the main fastness properties of the dyeings are listed. Comparisons are made between the fastness properties, in particular to light and washing, of dyes on acrylic, natural, and other man‐made fibres. Methods of dyeing unions of wool with Orion 42 and Acrilan are detailed.
Phase behavior of crystalline blends of poly(tetrafluoroethylene) and of random fluorinated copolymers of tetrafluoroethylene (1999)

In the present article, we investigate by differential scanning calorimetry (DSC) the thermal behavior (melting, crystallization, and crystal–crystal transitions) far from equilibrium of blends constituted of two crystalline polymers. In particular, the following blends are examined: PTFE–PFMVE, PTFE–FEP, and FEP–PFMVE where PTFE is poly(tetrafluoroethylene), PFMVE is poly(tetrafluoroethylene-co-perfluoromethylvinylether), and FEP is poly(tetrafluoroethylene-co-hexafluoropropylene). The two last ones are random tetrafluoroethylene copolymers with small amounts of comonomer. Our results indicate that, under the experimental investigated conditions, the blends containing PTFE do not give cocrystallization on cooling from the melt, although under very rapid crystallization conditions, quenching, the presence of the copolymer would seem to slightly influence PTFE crystallization (lower peak temperatures are observed for the crystalline transitions and the melting with respect to those of the neat homopolymer). The behavior of the FEP–PFMVE blend is completely different; in fact, our results indicate the occurrence of cocrystallization, then miscibility in the crystalline phase, for almost all compositions and all investigated experimental conditions. © 1999 John Wiley & Sons, Inc. J Polym Sci B: Polym Phys 37: 679–689, 1999
On the Place of Culture in Psychological Science (1993)

Based on a positivist‐empiricist mode of inquiry, mainstream psychology has been vigorously engaged in characterizing human lives in terms of mechanistic and individualistic constructions, with the aim of predicting and controlling the behaviour of acultural and decontextualized others. Committed to a belief in psychological universals, this enterprise is directed at verifying a peculiarly Western intelligibility. In doing so, it ignores the possibilities of other systems of understanding grounded in different cultures and “culture” remains marginalized in the psychological discourse. Viewed in terms of enablements and constraints, differing cultures may contribute a range of psychological intelligibilities, thus enriching the capacities for human relationship. This position is explored by contrasting an Indian with a Western conception of human functioning, with respect to grounding assumptions, and implications of a culturally informed psychology are discussed.
Runaway Reaction Hazards in Processing Organic Nitro Compounds (1998)

Pure organic nitro compounds, i.e., aromatic or aliphatic nitro compounds, decompose at high temperatures, exhibiting large decomposition exotherms. In most cases, the decomposition is violent or explosive. In practical process situations, nitro compounds are mixed with other chemicals or contaminated by impurities which lower their thermal stability. Contaminated nitro compounds or solutions of nitro compounds may decompose at much lower temperatures than the pure products. Their decomposition is less rapid but remains highly exothermic. Therefore, for practical reasons, the most relevant information in the field of process safety is to describe how reactants, solvents, and impurities may affect the organic nitro compounds' thermal stability and in which process situations this may be a hazard.
State-of-the-Art Vitamin D Assays: A Comparison of Automated Immunoassays with Liquid Chromatography–Tandem Mass Spectrometry Methods (2012)

Automated immunoassays demonstrated variable performance and not all tests met our minimum performance goals. It is important that laboratories be aware of the limitations of their assay.
Strain Differences in CNS and Lethal Effects of Hyperbaric Oxygen in Mice (1969)

Four strains of mice were tested for their response to the toxic effects of HBO. The order of strain sensitivity as measured by various parameters was: (i) incidence of clonic convulsions, C3H/anf > C57 BL/6 > HA/icr > CF-1; (ii) incidence of tonic convulsions, C3H/anf > HA/icr > C57BL/6 > CF-1; (iii) time to onset of clonic convulsions, C3H/anf ≅ HA/icr > C57BL/6 > CF-1; and (iv) survival time, C3H/anf ≅ HA/icr > C57BL/6 ≅ CF-1. The results of this study clearly demonstrate significant strain differences in the response of mice to HBO.
Discrimination of Vanadium from Zinc Using Gene Profiling in Human Bronchial Epithelial Cells (2005)

We hypothesized that gene expression profiling may discriminate vanadium from zinc in human bronchial epithelial cells (HBECs). RNA from HBECs exposed to vehicle, V (50 microM), or Zn (50 microM) for 4 hr (n = 4 paired experiments) was hybridized to Affymetrix Hu133A chips. Using one-class t-test with p < 0.01, we identified 140 and 76 genes with treatment:control ratios > or = 2.0 or < or = 0.5 for V and Zn, respectively. We then categorized these genes into functional pathways and compared the number of genes in each pathway between V and Zn using Fisher's exact test. Three pathways regulating gene transcription, inflammatory response, and cell proliferation distinguished V from Zn. When genes in these three pathways were matched with the 163 genes flagged by the same statistical filtration for V:Zn ratios, 12 genes were identified. The hierarchical clustering analysis showed that these 12 genes discriminated V from Zn and consisted of two clusters. Cluster 1 genes (ZBTB1, PML, ZNF44, SIX1, BCL6, ZNF450) were down-regulated by V and involved in gene transcription, whereas cluster 2 genes (IL8, IL1A, PTGS2, DTR, TNFAIP3, CXCL3) were up-regulated and linked to inflammatory response and cell proliferation. Also, metallothionein 1 genes (MT1F, MT1G, MT1K) were up-regulated by Zn only. Thus, using microarray analysis, we identified a small set of genes that may be used as biomarkers for discriminating V from Zn. The novel genes and pathways identified by the microarray may help us understand the pathogenesis of health effects caused by environmental V and Zn exposure.
The annual risk of melanoma progression. Implications for the concept of cure (1992)

Conditional probability methods permit estimation of future risks to address questions frequently asked by patients with cancer who want to know when they can be considered cured of cancer or when the risk of recurrent disease has decreased. These data on the future risk of recurrent disease and mortality can give a patient meaningful information on which to base life decisions.
Sailing Path Optimization Analysis with Uncertain Sea Conditions along Upwind-downwind Triangle Course (2013)

How to select an optimal sailing route with uncertain sea state information is a key to win. In this paper, firstly the roles of sea environmental parameters for sailboat sailing are analyzed based on hydromechanics principles. And then two-dimension sailing environmental model is set up for upwinddownwind triangle course based on course setting requests. And then the optimal sailing route is planned based on leg division and heading decision fuzzy comprehensive evaluation. Finally, considering the standard of sea conditions required in yachting area, simulations and data analysis indicate the effect of uncertain sea conditions in yachting arena on racing path optimization. The results will guide athletes and instructors to train scientifically.
Stable Sorting in Asymptotically Optimal Time and Extra Space (1978)

A stable sorting algonthm is one which does not permute the relative order of records which have equal keys. In The Art of Computer Programming, Vol 3, Exercise 5 5-3, Knuth poses the problem of finding a stable sorting algorithm which requires less than O(N ~2) time to sort N records, for arbitrary N, and which also requires no more than O(log N) bits of extra space (space in excess of that required to hold the N records)
Silicon carbide as a photoconductive switch material for high power applications (2006)

The entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf file.
Biochemical screening for Down’s syndrome in the first trimester of pregnancy (1993)

Down’s syndrome (DS) is the commonest single cause of severe mental retardation and accounts for just under a third of all cases. Until the late 1980’s population screening was based on offering amniocentensis to older women. This made little impact on the prevalence of DS because the majority (approximately 70%) of babies with DS are born to women under the age of 35 (Figure 1).
Diffusion Barrier Characteristics of Hf(C,N) Thin Films Deposited by Plasma Enhanced Metal Organic Chemical Vapor Deposition for Cu Metallization (1998)

Diffusion barrier characteristics of Hf(C,N) thin films for Cu metallization was investigated. Hf(C,N) thin films were deposited on Si(100) substrates by pulsed D.C. plasma enhanced metal-organic chemical vapor deposition (PE-MOCVD) using tetrakis diethyl amido hafnium (Hf[N(C 2 H 5 ) 2 ] 4 : TDEAHf) and N 2 as precursors. X-ray diffraction analyses, sheet resistance measurements and Rutherford backscattering spectroscopy analyses revealed that Hf(C,N) films prevent diffusion of Cu fairly well up to 600°C. At 700°C, however, Hf(C,N) films allowed a significant diffusion of Cu into the Si substrate.
Antimicrobial peptides: A natural alternative to chemical antibiotics and a potential for applied biotechnology (2003)

A large group of low molecular weight  natural compounds that exhibit antimicrobial activity has been isolated from animals and plants during the past two decades. Among them, cationic peptides are the most widespread. Interestingly, the variety and diversity of these peptides seem to be much wider than suspected. In fact, novel classes of peptides with varying chemical propertiescontinue to be isolated from different vertebrate and invertebrate species, as well as  from bacteria. To the early characterized peptides, mostly cationic in nature,  anionic peptides, aromatic dipeptides, processed  forms of oxygen-binding proteins and processed forms of structural and functional proteins can now be added, just to name a few. In spite of  the astonishing diversity in structure and chemical nature displayed by these molecules, all of them present antimicrobial activity, a condition that has led researchers to  consider them as natural and as such a new and innovative alternative to chemical antibiotics with a promising future as biotechnological tools. A resulting new generation of anti microbial peptides (AMPs) with higher specific activity and wider microbe-range of action could be constructed, and hopefully endogenously expressed in genetically-modified organisms.
Determination of the Period of the Formation and Size of Sieve Element Area and Sieve Pore (2002)

Streptanthus 조직배양 세포에서 유조직 세포로부터 사부 세포의 발달 동안 설탕 운반자는 유도되었고, 단당류인 포도당의 운반자는 사라졌다 (Cho 1998). Streptanthus 조직배양 세포에서 유도된 사부영역과 사공은 sieve endoplasmic reticulum (SER)과 p-protein 합성이 거의 완성되는 시기에 형성되며, SER이 새로 합성된 세포벽을 에워싼 후에 세포벽이 분해되기 시작하였다. 세포벽의 분해와 사공의 형성은 비교적 규칙적으로 진행되었다. 사공의 모양은 계란형이었고, 사공의 외부크기는 세로 1.2 <TEX>$\mu\textrm{m}$</TEX>~l.6 <TEX>$\mu\textrm{m}$</TEX>, 가로 0.8 <TEX>$\mu\textrm{m}$</TEX>~l.3 <TEX>$\mu\textrm{m}$</TEX>, 다양하고 사공의 내부크기는 별모양과 유사한 불규칙한 형태였다. 두 사부세포 사이에서 사공의 수는 <TEX>$\mu\textrm{m}$</TEX><TEX>$^2$</TEX>당 2개~7개였고, 육상체를 포함한 사공벽에 두께는 0.05 <TEX>$\mu\textrm{m}$</TEX>~0.07 <TEX>$\mu\textrm{m}$</TEX>,의 두꺼운 벽으로 구성되었다. 사공영역과 사공의 형성에 필요한 에너지는 세포벽 가까이에 위치하고 있는 미토콘드리아에서 얻을 것으로 추측하며, 사공 형성에 대한 SER의 역할은 아직까지 설명할 수 없었다. During the phloem development from parenchyma cells in a suspension culture of Streptanthus induced sucrose carrier and glucose carrier disappeared. Sieve element area and sieve pore induced suspension culture of Streptanthus were formed almost at the last period of the synthesis of sieve endoplasmic reticulum (SER) and p-protein. The new synthesized cell wall begann to digeste only after the new cell wall was surrounded by SER. The digested region of the cell wall and the formed region of sieve pore were regular comparatively. The completed sieve pore was an oval form, and the outer portion of sieve pore varied, ca 1.2 <TEX>${\mu}{\textrm}{m}$</TEX>~1.6 <TEX>${\mu}{\textrm}{m}$</TEX> in longitudinal, 0.8 <TEX>${\mu}{\textrm}{m}$</TEX>~1.3 <TEX>${\mu}{\textrm}{m}$</TEX> in tangential, and the inner size of sieve pore was irregular form of a star-like shape. The number of sieve pore between sieve cells was ca 2~7 per <TEX>${\mu}{\textrm}{m}$</TEX><TEX>$^2$</TEX> and the sieve pore wall with callose was 0.05 <TEX>${\mu}{\textrm}{m}$</TEX>~0.07 <TEX>${\mu}{\textrm}{m}$</TEX> in thickness. The energy for the formation of sieve element area and sieve pore might be supplied by mitochondria near the new cell wall and the role of SER remains to be illucidated.
<i>In situ</i> investigation on dynamic suspending of microdroplet on lotus leaf and gradient of wettable micro- and nanostructure from water condensation (2008)

Dynamic suspending behavior of microdroplet on fresh lotus leaf is in situ investigated at micro- and nanolevels, by water condensation via environmental scanning electronic microscopy. The observation and analysis reveal that a gradient of wettable micro- and nanostructure is formed along the exterior surface of papilla including nanohairs during water condensation. This gradient introduces a tendency of directional movement and enables the microdroplet move out of the valley of papillae until the microdroplet is suspended on the tops of papillae. This finding is significant to understand the mechanism of self-cleaning.
THERMAL OBSERVATION OF A MODULATED INPUT FOR A 2.5GHZ CMOS POWER AMPLIFIER Part 2: Temperature Sensor (2011)

The temperature sensor used is based on the usual two bipolar transistors temperature sensor with some modifications to allow for external calibration (or “re-centering”).