gebhart/patrepeval huggingface dataset:
Efficient, high-speed ablation of soft tissue with few-microjoule, femtosecond pulse bursts (2014)

Femtosecond pulses hold great promise for high-precision tissue removal. However, ablation rates are severely limited by the need to keep average laser power low to avoid collateral damage due to heat accumulation. Furthermore, previously reported pulse energies preclude delivery in flexible fibers, hindering in vivo operation. Both of these problems can be addressed through use of groups of high-repetition-rate pulses, or bursts. Here, we report a novel fiber laser and demonstrate ultrafast burst-mode ablation of brain tissue at rates approaching 1 mm$^3$/min, an order of magnitude improvement over previous reports. Burst mode operation is shown to be superior in terms of energy required and avoidance of thermal effects, compared to uniform repetition rates. These results can pave the way to in vivo operation at medically relevant speeds, delivered via flexible fibers to surgically hard-to-reach targets, or with simultaneous magnetic resonance imaging.
Room-Temperature and Solution-State Observation of the Mixed-Valence Cation Radical Dimer of Tetrathiafulvalene, [(TTF)<sub>2</sub>]<sup>+•</sup>, within a Self-Assembled Cage (2005)

A mixed-valence state of the cation radical tetrathiafulvalene dimer, [(TTF)2]+*, is generated by the electrochemical oxidation of a stacked TTF dimer accommodated within an organic-pillared coordination cage. This mixed-valence species is remarkably stable (t1/2 = approximately 1 day at room temperature in aqueous solution under air) and clearly characterized by cyclic voltammogram and electronic absorption spectroscopy.
Influence of the Double Cone Drill Geometry on the Holes Quality during Drilling Multi-Stack Made of CFRP/Al (2014)

International audience
Developmental and Tissue-specific Expression of Mouse Pelle-like Protein Kinase (1996)

The NF-kappaB/c-Rel proteins are a family of evolutionarily conserved transcription factors activated during development that in the adult, mediate many processes including the immune response. A high degree of sequence similarity is shared between the NF-kappaB/c-Rel family of transcription factors and the Drosophila Dorsal protein as well as between its cytoplasmic inhibitor, IkappaBalpha, and the Drosophila Cactus protein. Genetic analyses of Dorsal have defined components of a signaling pathway for Dorsal activation, including a serine/threonine kinase, Pelle, placed upstream of Dorsal and Cactus. We demonstrate that this pathway is likely to be conserved in mammals by the isolation of a cDNA that encodes a novel mouse protein highly related to Pelle, mPLK (mouse Pelle-like protein kinase). Expression of mPLK mRNA is developmentally regulated in the mouse and in adult tissue mPLK expression is greatest in the liver, a tissue that expresses a high level of NF-kappaB. Recombinant mPLK produced in bacteria is a protein kinase capable of autophosphorylating and phosphorylating IkappaBalpha.
The effects of bulk traps on the performance of bulk channel charge-coupled devices (1974)

The effects of bulk traps on the transfer effciency and transfer noise in bulk channel charge-coupled devices (BCCD's) are calculated for different charge packet sizes and operating frequencies. These predictions are compared with experimental results and the distribution and density of bulk states in actual devices are thereby measured. The measured low transfer inefficiency of 10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">-4</sup> per transfer with no intentionally introduced background charge and low transfer noise are shown to be due to a low bulk state density of 2 × 10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">11</sup> /cm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sup> . A detailed comparison of estimated noise in both surface and bulk channel versions of an image sensor and an analog delay line show that BCCD's are very attractive for low-light level imaging but not as attractive for analog signal processing.
Positive Association Between the Lys198 Asn Polymorphism in the Endothelin-1 and Blood Pressure in Obese Japanese Subjects: Ohasama Study (2000)

P117 A recent report by Tiret et al. (Hypertension 33, 1999) revealed that a G/T polymorphism with an amino acid substitution (Lys to Asn) at codon 198 in the exon 5 of endothelin 1 gene (ET1) is associated with blood pressure in overweight people using two epidemiological studies, ECTIM and Glasgow Heart Scan Study. They suggested that G/T polymorphism strongly interacted with body mass index (BMI) in the determination of blood pressure levels. To examine the interaction among G/T polymorphism of ET1, BMI and blood pressure, we carried out an association study using a general population. Subjects (n=1,446) were recruited from Ohasama population, which is a cohort in a rural community of northern Japan. The research protocol was approved by the Institutional Review Board of the Tohoku University. DNA was extracted from the buffy coat of the participants using QIAamp DNA Blood Kit (Qiagen Inc.). G/T polymorphism of ET1 was determined by TaqMan PCR method, which is a powerful tool for semiautomatic genotype determination in a large number of samples. The frequency of T198 allele in Japanese (26%) was significantly higher than that in Caucasians (23%). The baseline characteristic (age, BMI, SBP, DBP, antihypertensive treatment) of all subjects was not significantly different according to the genotype of G/T polymorphism. In the obese subjects (≥25kg/m2), however, SBP and DBP were significantly associated with G/T polymorphism. Blood pressure level in the subjects carrying T198 allele was 2.6 mmHg in systolic (p
Photonic Bandgap Fibers for High-Power CW and Pulsed Applications (2008)

paper Tu.D3.1
Grid integration of solar PV power generating system using QPLL based control algorithm (2014)

This paper deals with the grid integration of a double stage solar photovoltaic (SPV) power generating system using two-quadrature PLL (QPLL) based control, which also mitigates power quality problems in three phase, three wire distribution system. The proposed solar PV grid interfaced system consists of solar PV array, dc-dc boost converter, voltage source converter (VSC) and connected linear/nonlinear loads. The maximum power is tracked from SPV array using incremental conductance maximum power point tracking (MPPT) technique. The proposed solar PV power generating system provides load balancing, eliminates harmonics, corrects the power factor, and regulates at PCC (Point of Common Coupling) voltages under different loads. The proposed system is modeled and simulated in the MATLAB/Simulink and results are shown to validate the design and control algorithm.
Introduction to the Special Issue on the 2012 IEEE International Solid-State Circuits Conference (2012)

The IEEE International Solid-State Circuits Conference (ISSCC) is the foremost global forum for presenting advances in solid-state circuits and systems-on-a-chip. Every year since its first issue, the IEEE JOURNAL OF SOLID-STATE CIRCUITS has highlighted some well-received papers from the most recent ISSCC in special issues. This special issue covers the ISSCC conference held in San Francisco, CA, February 19-23, 2012. Session chairs and co-chairs initially recommended papers for publication, with final decision for inclusion based on peer review. This January issue includes the topics from the low power and high performance digital, memory, technology directions as well as imagers, medical and sensors. Five innovative papers were selected from the Energy Efficient Digital sessions of the ISSCC 2012 for this special issue. Two of the papers describe ultra-low-power processors. There are also two energy efficient special function SoC papers: an object recognition processor and a 60 GHz transceiver. The last paper describes an enhancement of the razor technique.
ChemInform Abstract: Stereoselective Bromohydrin Formation from β‐Hydroxy Sulfoxides Mediated by the Pendant Sulfoxide. (2000)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Thermal degradation of polyvinyl chloride (1965)

The thermal degradation of polyvinylchloride has been investigated by several workers, and different mechanisms have boon suggested for the degradation. In the thermal degradation of ITC, hydrochloric acid is evolved and a coloured residue is loft, In the present work, the problem was tackled in four different ways. The main aim was to assign a definite mechanism for the degradation. Commercial polymer prepared by suspension method, Geon 111 (JLB-49) was used for these measurements. The influence of solvents on the degradation. was investigated by carrying out the dohydrochlorination in presence of different solvents, The acid evolved was estimated by titrating it against standard caustic soda solution, The solvents used wore, benzophepnone, dioctylphthala-te, dichloronaphthalene, benzyl alcohol, tritoluylphosphate and ethyl benzoate, it was observed that solvents have an influence on the dehydrochlorination, the rate being greatest in benzophenone and tritoluylphosphate. A attempt has been made to explain these effects. The activation energy in the temperature range 187-243
RET/PTC-induced gene expression in thyroid PCCL3 cells reveals early activation of genes involved in regulation of the immune response (2005)

RET/PTC rearrangements represent key genetic events involved in papillary thyroid carcinoma (PTC) initiation. The aim of the present study was to identify the early changes in gene expression induced by RET/PTC in thyroid cells. For this purpose, microarray analysis was conducted on PCCL3 cells conditionally expressing the RET/PTC3 oncogene. Gene expression profiling 48 h after activation of RET/PTC3 identified a statistically significant modification of expression of 270 genes. Quantitative PCR confirmation of 20 of these demonstrated 90% accuracy of the microarray. Functional clustering of genes with greater than or less than 1.75-fold expression change (86 genes) revealed RET/PTC3-induced regulation of genes with key functions in apoptosis (Ripk3, Tdga), cell-cell signaling (Cdh6, Fn1), cell cycle (Il24), immune and inflammation response (Cxcl10, Scya2, Il6, Gbp2, Oas1, Tap1, RT1Aw2, C2ta, Irf1, Lmp2, Psme2, Prkr), metabolism (Aldob, Ptges, Nd2, Gss, Gstt1), signal transduction (Socs3, Nf1, Jak2, Cpg21, Dusp6, Socs1, Stat1, Stat3, Cish) and transcription (Nr4a1, Junb, Hfh1, Runx1, Foxe1). Genes coding for proteins involved in the immune response and in intracellular signal transduction pathways activated by cytokines and chemokines were strongly represented, indicating a critical role of RET/PTC3 in the early modulation of the immune response.
Modulation of cytokine release from colonic explants by bacterial antigens in inflammatory bowel disease (2003)

The intestinal flora play an important role in experimental colitis and inflammatory bowel disease (IBD). Using colonic explant cultures from 132 IBD and control subjects, we examined tumour necrosis factor-alpha (TNF-alpha), interleukin (IL)-1 and interleukin-1 receptor antagonist (IL-1RA) production in vitro in response to bacterial activators. Unstimulated TNF-alpha release was increased significantly in rectal biopsies from involved IBD tissue, correlating with inflammation severity. Whereas lipopolysaccharide (LPS) only moderately stimulated TNF-alpha production from inflamed tissue, pokeweed mitogen (PWM) induced its release in all groups, with a stronger response in involved IBD tissue. Superantigen staphylococcal enterotoxin A (SEA) had a similar, but weaker effect. SEB was observed to be the strongest inducer of TNF-alpha for all groups, again with a more marked response in inflamed tissue. Stimulated release of IL-1 was considerably less than for TNF-alpha. The superantigens' superior potency over LPS was not as marked for IL-1 as it was for TNF-alpha. In addition to IL-1, IL-1RA release was also triggered by the bacterial products. The net effect of activation on the IL-1RA/IL-1 ratio was relatively modest. Release of the proinflammatory cytokines TNF-alpha and IL-1, as well as that of the anti-inflammatory cytokine IL-1RA was increased by incubation of colonic tissue with bacterial factors. TNF-alpha production and release was increased significantly in involved colonic explants from IBD. SEB was even capable of inducing TNF-alpha release from uninvolved colonic tissue.
Gary Litman, Ph.D., Director of University of South Florida College of Medicine, Children's Research Institute, St. Petersburg, Florida (2005)

Gary Litman, Ph.D., is Director of the University of South Florida College of Medicine, Children's Research Institute, St. Petersburg, Florida, and Vice Chairman for Basic Sciences, Department of Pediatrics. In addition, he is a Professor in the Department of Biochemistry and Molecular Biology at the University of South Florida, a Distinguished University Professor and Hines Professor in the Department of Pediatrics in the university's College of Medicine, Director of the Laboratory of Molecular Genetics at All Children's Hospital, and Adjunct Scientist in the Biomedical Program at Mote Marine Laboratory. Dr. Litman received a Bachelor's degree and a Ph.D. in microbiology from the University of Minnesota. He is a former Chairman of the NIH Zebrafish Review Group 1 Study Section and serves on the editorial boards of Developmental Immunology, Cancer Control: Journal of the Moffitt Cancer Center, and Immunogenetics.
QUANTUM COMPUTERS MADE LUCID (2003)

RETURN TO ISSUEPREVBook ReviewNEXTQUANTUM COMPUTERS MADE LUCIDA SHORTCUT THROUGH TIME: The Path to the Quantum Computer, by George Johnson, Knopf, 2003,224 pages, $24 (ISBN: 0-375-41193-3)DANIEL LIDARCite this: Chem. Eng. News 2003, 81, 32, 36–37Publication Date (Print):August 11, 2003Publication History Published online13 November 2010Published inissue 11 August 2003https://pubs.acs.org/doi/10.1021/cen-v081n032.p036https://doi.org/10.1021/cen-v081n032.p036book-reviewACS PublicationsCopyright © 2003 AMERICAN CHEMICAL SOCIETYArticle Views18Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options SUBJECTS:Circuits,Quantum entanglement,Quantum mechanics,Semiconductors,Undergraduates Get e-Alerts
Favorable outcomes with laparoscopic surgery for rectal cancer (2010)

Liakakos et al. [1] concluded from a retrospective series of1,057 selected patients studied by Miyajima et al. [2] thatlaparoscopic surgery for rectal cancer is safe. Althoughcohort studies have shown safety, the most important out-comes such as disease-free survival and the recurrence rateneed to be demonstrated in prospective randomized con-trolled trials before laparoscopic surgery is accepted as thestandard approach.Laparoscopic resection of colonic cancer is proved to besafe, with no difference in long-term oncologic outcomecompared with open surgery [3–5]. However, long-termoutcome data after laparoscopic surgery for rectal cancerstill are not available.Only 5 years ago, the ﬁrst study investigating the qualityof the mesorectal dissection with 25 patients was published[6]. The ﬁrst randomization was done in the conventionalversus laparoscopically-assisted surgery in ColorectalCancer (CLASICC) trial with 253 patients treated withlaparoscopic surgery. The conversion rate at the beginningof the trial was 34%, which decreased to 16% during thesixth year of the study [5]. This high conversion rate in arelatively small study group was due the experience curveeffect.Miyajima et al. [2] concluded that laparoscopy is fea-sible and safe for selected patients with rectal cancer, withfavorable short- and mid-term outcomes after a mean fol-low-up period of 30 months. This retrospective study, notintended to be a comparison between open and laparo-scopic surgery, was reported without long-term outcomedata. Therefore, as stated by Liakakos et al. [1], more dataare needed from randomized controlled trials, if feasible, tosupport the hypothesis of better oncologic outcomes forclosed rather than open surgery for rectal cancer.Currently, several multicenter randomized controlledtrials comparing laparoscopic and open surgery for rectalcancer are registered (Clinicaltrials.gov) and recruitingpatients, including the laparoscopic-assisted resection oropen resection in treating patients with Stage IIA, StageIIIA, or Stage IIIB rectal cancer (NCT00726622) trial bythe American College of Surgeons (estimated primarycompletion date, August 2010) and the Phase II trial toevaluate laparoscopic surgery for Stage 0/1 rectal carci-noma (Lap RC), NCT00635466 (estimated study comple-tion date, 2016).In addition, the comparing laparoscopic and open sur-gery for rectal cancer (COLOR II) trial (NCT00297791)will fulﬁl the profound need for a well-designed and per-formed randomized trial. Recently, this COLOR II trialﬁnished randomization of 1,100 patients. The short-termresults will be presented by the colorectal cancer laparo-scopic or open resection study group on a short notice.The primary end point of the COLOR II trial is thelocoregional recurrence rate 3 years postoperatively. Untilthese data become available, we believe that open totalmesorectal excision must be regarded as the gold standardtreatment for rectal cancer.
Self-Report Measures of Mood and Morale in Elderly Depressives (1981)

The self-report scales of mood and morale were administered to 45 elderly in-patient depressives and 45 non-patient controls, matched for age and sex. The responses of the two groups differed significantly in the predicted direction. When 18 patients from the depressive group were re-tested 6 to 8 weeks later, at discharge, significant declines in self-reported depression, and increases in "life-satisfaction' were reported. Within the depressive group, there was a significant relationship between "overt' depressive behaviour on the ward and self-reporting of greater depressive symptoms, and lower "life-satisfaction'. The importance of independent validation of self-report measures of mood and morale in elderly populations is discussed.
Spectral brightness and other improvements to the tunable ArF excimer laser (1998)

We present two oscillator designs and a new amplification design which improves many characteristics of the dual-discharge tube tunable ArF excimer laser. We demonstrate bandwidths from 0.17–11.0 cm−1 (5–330 GHz) can be selected by appropriate choice of oscillator slit width and diffraction-grating dispersion. Amplification is achieved using three consecutive passes through the discharge tubes. This amplifier design decreases divergence (9×diffraction limit) and increases output energy (33%), locking efficiency (20%), range of tunability (40%), and spectral brightness (two orders-of-magnitude) when compared to the standard unstable-resonator amplifier.
An Analysis of Restriction Endonuclease Sites in Cyanophages Infecting the Heterocystous Cyanobacteria Anabaena and Nostoc (1988)

An analysis of restriction endonuclease cleavage of DNA isolated from cyanophages that infect Anabaena and Nostoc species of cyanobacteria has provided evidence for counter-selection of restriction endonuclease sites. These include sites containing subsequences which are methylated by host (Anabaena PCC 7120) methylase(s) akin to the dam and dcm enzymes of Escherichia coli. Other sites which are counter-selected have no common sequence structure. The latter include those of the endogenous restriction endonucleases of the host, but other absent sequences are not attributable to isoschizomers of any known Anabaena or Nostoc restriction endonuclease. The cyanophages differ in their tolerance to DNA methylation. Isolates A-4L, AN-13 and AN-23 do not tolerate adenosine methylation in the GATC sequence whereas two cyanophages, A-1L and AN-10 (which are related) do tolerate dam-like methylation of this sequence. In addition, A-1L allows cytosine methylation at GGCC sequences, but AN-10 has counter-selected these sequences and the remaining sites are not methylated. Analysis of native and cloned A-4L DNA suggests that counter-selection has occurred against all sequences which would be methylated by the host at either adenosine or cytosine nucleotides.
MMT-05 SILICON-BASED FLAPPING WINGS USING SELF-ACTUATED STRESS DISTRIBUTION (2003)

The objective of this project is to develop a battery - powered ornithopter Micro Air Vehicle (MAV) using MEMS technology. The major goal of the MAV project focuses on flapping wing propulsion systems. This paper summarizes the bottom-up design approach involved in new IC-processed micrometer thick silicon wings. The proposed MEMS - based wings have been designed so as to allow two degrees of freedom : flapping and feathering. The wings are actuated through nearly 20,000 elementary actuation cells that are distributed over the upper surface of single crystal silicon structures.
Comment on “252Cf fission-neutron spectrum using a simplified time-of-flight setup: An advanced teaching laboratory experiment” [Am. J. Phys. 81, 112–119 (2013)] (2014)

Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter Facebook Reddit LinkedIn Tools Icon Tools Reprints and Permissions Cite Icon Cite Search Site Citation F. D. Becchetti; Comment on “252Cf fission-neutron spectrum using a simplified time-of-flight setup: An advanced teaching laboratory experiment” [Am. J. Phys. 81, 112–119 (2013)]. American Journal of Physics 1 July 2014; 82 (7): 706. https://doi.org/10.1119/1.4876218 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAmerican Association of Physics TeachersAmerican Journal of Physics Search Advanced Search |Citation Search