gebhart/patrepeval huggingface dataset:
Low BER radio design for wireless local loop applications (2002)

High performance full duplex 1.4 to 2.8 GHz radios for wireless local loop telephony application have been developed and are described. The radios are designed to handle both QPSK modulation and spectrally efficient quadrature amplitude modulation (QAM) at a bit error rate of 1E-06. The radios are a critical component in a very sophisticated FDMA system that is currently installed and operational in several countries throughout the world. The system offers copper quality voice service to subscribers and is capable of supporting advanced digital services such as ISDN. The radios are designed to transmit over distances as great as 50 km. The base station radio achieves a nominal output power of approximately 1 Watt. The remote station radio located at the subscriber's residence achieves a nominal output power of approximately 0.5 Watts. The transmitter amplifiers in both the base and remote radios are operated at approximately 5 dB of cutback to preserve linearity which is especially critical in the QAM mode. The power managed system requires 60 dB of ALC range.
2-Carbomethoxy-1,3-butadiene: an electronically activated diene in [4 + 2] cycloadditions with electron-deficient dienophiles (1993)

Cross Diels–Alder reactions between 2-carbomethoxy-1,3-butadiene 1 and electron-rich dienes were carried out. It was found that diene 1 had a higher reactivity than even the well-known Danishefsky diene in its Diels–Alder cycloaddition with electron-deficient dienophiles. In addition, (Z)-1-methylthio-3-carbomethoxy-1,3-butadiene 11 was found to have a higher reactivity than (Z)-1-methylthio-1,3-butadiene and (Z)-2-carbomethoxy-1,3-hexadiene, while both (E)- and (Z)-1,2-(bis)-carbomethoxy-1,3-butadiene 14 reacted efficiently with maleic anhydride to give the corresponding cy-cloadduct 15.
Acrosome Morphology of Boar Spermatozoa during in vitro Aging (1974)

Changes in the acrosome morphology of boar spermatozoa during in vitro storage were assessed by phase-contrast microscopy. During storage of the spermatozoa at 15 and 25 C the apical ridges enlarged and their smooth crescent-shape became irregular. The acrosomes deteriorated more rapidly when stored at 25 C than at 15 C and deteriorated more rapidly in Tris and saline extenders than in citrate and IVT extenders. Five semen extenders were compared for their ability to maintain sperm motility and acrosome morphology during in vitro storage for 3 days at 25 C and for 7 days at 15 C. Maintenance of acrosomes with normal apical ridges and sperm motility was similar for Beltsville LI (BLI), Purdue extender (PE), and CO2-saturated-IVT-extended semen at both 15 and 25 C. Greater acrosome deterioration at 25 C and lower sperm motility at 15 and 25 C occurred in the semen extended in IVT without CO2 saturation. The poorest preservation of acrosome morphology and sperm motility occurred in glucose-bicarbonate (GB) extended semen.
Effects of Lecithin-Emulsified Perfluorochemical Compounds in Ischemic Brain Injury (1994)

A lecithin-emulsified "Pluronic F-68"-free perfluorochemical compound, named F-1,3-DMA, was tested as a new agent in the prevention of central nervous tissue ischemia. A permanent ischemia leading to cerebral infarction was induced after microsurgical exposure and occlusion of the internal carotid, anterior, and middle cerebral arteries in the rabbit. Following arterial occlusion, F-1,3-DMA was administered intravenously, in a solution rendered isotonic to plasma, over a 30 minute period. The F-1,3-DMA was well tolerated. Hemodynamic, cardiovascular and metabolic parameters were not affected by the infusion of F-1,3-DMA. Although PO2 remained virtually unchanged, animals treated with F-1,3-DMA (n = 9), had smaller infarct volume by 61 percent as compared to the control (n = 8) group (P < 0.04, Student's t-test). Histopathology did not reveal any F-1,3-DMA related damage in the non-infarcted brain. These results suggest that F-1,3-DMA has nervous tissue ischemia protective properties possibly because of microflow effects although O2 transport to "local" tissue may be enhanced as well. We believe that further research is necessary in order to make clinical trials of F-1,3-DMA possible.
Generating Picosecond X-Ray Pulses with Beam Manipulation in Synchrotron Light Sources (2006)

We show that X-ray pulses one order of magnitude shorter than the electron bunch length can be obtained through synchrobetatron coupling. A 6-ps rms visible light pulse from a 30-ps rms electron bunch was observed using a streak camera. Theory, simulation, and experimental results are presented.
Expression of multidrug transporter<i>MRP4/ABCC4</i>is a marker of poor prognosis in neuroblastoma and confers resistance to irinotecan<i>in vitro</i> (2005)

Members of the multidrug resistance-associated protein (MRP) family of transporters are believed to contribute to cytotoxic drug resistance and chemotherapy failure. We observed frequent MRP4 overexpression in aggressive primary neuroblastoma, a disease for which we have previously shown MRP1 to be a prognostic indicator. High MRP4 expression correlated with MYCN oncogene amplification and was significantly associated with poor clinical outcome. Although MRP4 is known to transport some nucleoside analogues, it has not previously been associated with resistance to drugs used to treat solid tumors. We now show that it mediates substantial resistance in vitro to the topoisomerase I poison irinotecan/CPT-11 and its active metabolite SN-38. These results suggest that MRP4 will be a useful prognostic marker for neuroblastoma and that clinical trials of irinotecan as a neuroblastoma treatment should monitor MRP4 expression. The same may be true for other tumor types expressing high levels of the transporter.
Blue/green lasers focus on the market (1994)

The authors present a review of past, present, and future blue/green laser technologies. They discuss: II-VI semiconductor materials and alternate approaches (including the use of SiC and III-V nitrides, e.g. GaN, AlN); laser diode design; multiple quantum well approaches; contacting to p-ZnSe; and remaining challenges.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
High energy negative deuterium beams using double charge-exchange or surface production (1977)

Experimental and theoretical research on production of negative ion beams is described. Results from a double charge-exchange experiment include 10 ms pulses of 100 ma of D/sup -/ accelerated to 60 kV. Equilibrium fractions of D/sup -/ in several metal vapors are presented. Mechanisms and measurements of D/sup -/ on surfaces are described, and a scheme is shown for producing high current, high energy beams originating on surfaces.
Redox-Dependent Magnetic Alignment of <i>Clostridium pasteurianum</i> Rubredoxin:  Measurement of Magnetic Susceptibility Anisotropy and Prediction of Pseudocontact Shift Contributions (1999)

An analysis of the magnetic field dependence of one-bond couplings has yielded the magnetic susceptibility anisotropies for Clostridium pasteurianum rubredoxin (Rdx) in its oxidized Fe(III) and reduced Fe(II) states. Experimental one-bond 1HN−15N and 1Hα−13Cα couplings were measured at two field strengths (corresponding to 400 and 750 MHz 1H frequencies) and decomposed into their field-independent scalar (1J) and field-dependent dipolar (1D) components. The total numbers of measured dipolar couplings (1HN−15N plus 1Hα−13Cα) were 50 for oxidized Rdx and 49 for reduced Rdx. The atom pairs giving rise to these signals are located >11 Å from the iron; those closer to the iron are too broad to be resolved in two-dimensional NMR spectra and may exhibit large Fermi contact shifts. A five-dimensional grid search and Powell minimization of the difference between each set of measured dipolar couplings and those calculated from an X-ray crystal structure of Fe(III) Rdx yielded the magnitude and orientation of the magnetic susceptibility anisotropy in each oxidation state. (The data for Fe(II) Rdx were analyzed in terms of the X-ray structure for Fe(III) Rdx because no X-ray coordinates were available for the reduced rubredoxin. The assumption underlying this approximation, that the conformations of the oxidized and reduced rubredoxin are very similar in protein regions >11 Å from the iron, was validated by comparisons of experimental and calculated pseudocontact shifts.) The axial and rhombic magnetic susceptibility anisotropies were 5.3 × 10-28 and 2.1 × 10-28 cm3/molecule, respectively, for oxidized Rdx, and 20.3 × 10-28 and 9.7 × 10-28 cm3/molecule, respectively, for reduced Rdx. The derived susceptibility tensors were then used to calculate the pseudocontact contributions to the backbone 1Hα and 1HN chemical shifts of Rdx in the two oxidation states. Oxidation-state-dependent pseudocontact shifts were found to account fully (within experimental error) for the experimental chemical shift differences exhibited by these backbone signals. Thus, the results are consistent with the absence of appreciable conformational differences between Fe(III) Rdx and Fe(II) Rdx in the protein regions represented by the NMR data (>11 Å from the iron).
Handwritten Digit Recognition Based on Classification Functions (2020)

As a model of a machine learning, an incompletely specified classification function is used. As a benchmark problem, data for handwritten digits with 28 × 28 images were used. This data was converted into one with 14×14 = 196 pixels using a space filter. Also, the value of each pixel was binarized. With this operation, the original data was converted into a 196variable classification function that takes values from 0 to 9. For the training data, we had k = 58191 samples. Using a linear transformation, the 196-variable classification function was converted into a 25-variable function. We applied the testing data consisting of 9569 samples. The reduced classification function produced correct answers for 97.3% of the recognized test data. For unrecognized test data, the circuit for the reduced classification function produced "unrecognized" signals. The recognition circuit for handwritten digits can be implemented by a simple architecture: a cascade of a linear circuit and a memory. To increase the recognition rate, we also present methods using multiple classification functions and voters.
An Indoor Planning Tool with Both Antennas Placement and Wiring Optimization (1999)

As the wireless communications systems become more and more popular, the subscribers want to use their phone in all the places they live. In these conditions, an indoor planning tool may be very useful for the operators to offer their subscribers the best coverage with the lowest costs. The indoor planning tool that is presented here is a combination of a prediction and an optimization tool. The prediction tool is based on a UTD (Uniform Theory of Diffraction) - Ray Launching. The optimization tool is based on both placement and wiring optimization. This is probably the main originality of this work as the question of the wiring between the BTS and the antennas is rarely studied although it is a very important one.
Sofosbuvir, velpatasvir, and voxilaprevir for patients with failure of previous direct-acting antiviral therapy for chronic hepatitis C: Results from the German Hepatitis C-Registry (DHC-R) (2020)

Despite the high effectiveness of direct-acting antivirals for the treatment of hepatitis C, a small proportion of patients do not respond to approved regimens. The combination regimen of SOF/VEL/VOX was recently approved for patients with failure to prior NS5A-based treatment. In this German real-world cohort including patients with cirrhosis (27.3 %) and previous decompensation events, 12 weeks of SOF/VEL/VOX resulted in high virologic response rates irrespective of disease severity and prior DAA regimen. Adverse events were mostly mild or moderate and comparable to those seen in the approval studies.
The Translation <i>in vitro</i> of mRNA from Developing Cysts of <i>Artemia salina</i> (1976)

Successive stages in the development of the brine shrimp cyst were used as a model for studying differentiation at the level of mRNA transcription and translation. The poly (A)-containing mRNA from dormant cysts and free-swimming larvae (nauplii) was found to be efficiently translated in a wheat-germ cell-free system, and electrophoretic patterns of translation products in vitro resembled those of the endogenous proteins extracted from the equivalent developmental stages. Each stage, however, exhibits a characteristic protein pattern. Two low-molecular-weight proteins prominent in the cyst disappeared almost completely in the nauplius stage, whereas the proportion of actin increased 3-fold. Parallel patterns were observed upon translation in vitro of the respective mRNA preparations. The percentage of the acidic protein, tubulin, decreased somewhat during development.
The calcar screw in angular stable plate fixation of proximal humeral fractures - a case study (2011)

The placement of calcar screws in the angular stable plate fixation of proximal humeral fractures is associated with less secondary loss of reduction by providing inferomedial support. An increased risk for complications could not be shown.
Accelerated phase contrast imaging using compressed sensing with complex difference sparsity (2012)

DOAJ is a unique and extensive index of diverse open access journals from around the world, driven by a growing community, committed to ensuring quality content is freely available online for everyone.
Transformation Superplasticity in the Commercial Low Carbon Steels under Rapid Heating (1975)

The transformation superplasticity occurs depending not on the factor of micro-fine structure required in the micro-grained superplasticity but on the factor of the transformation proceeding under the applied stress. In this report the effects of heating rates upon the transformation superplasticity generated during the ithothermal process were investigated in the low carbon steels with the same method done for pure iron in the previous paper.The main results obtained are as follows.(1) The transformation superplasticity in the low carbon steels occurred in the range of 750 to 1050°C under rapid heating (the heating rate: 35∼100°C/sec).(2) The linear law between the applied stress τ and the total strain γ per cycle was recognized within τ=0.6 kg/mm.(3) The flow curves induced by the transformation superplasticity were determined at each heating rate. The value of the strain rate sensibility m was about 1.(4) The transformation superplasticity was not observed in the A1∼A3 point (α+γ) region during the isothermal process.
Representation Theoretical Meaning of the Initial Value Problem for the Toda Lattice Hierarchy II (1991)

The Toda lattice hierarchy is shown to have the virtual Bruhat decomposition of the A_∞ group as its parameter space, instead of the Grassmann manifold for the KP hierarchy. The small cells of the Bruhat decomposition are examined. The parametrization of the KP hierarchy is utilized for this purpose with the help of the Miura transformation.
Distinguishing autofluorescence of normal, benign, and cancerous breast tissues through wavelet domain correlation studies (2011)

Using the multiresolution ability of wavelets and effectiveness of singular value decomposition (SVD) to identify statistically robust parameters, we find a number of local and global features, capturing spectral correlations in the co- and cross-polarized channels, at different scales (of human breast tissues). The copolarized component, being sensitive to intrinsic fluorescence, shows different behavior for normal, benign, and cancerous tissues, in the emission domain of known fluorophores, whereas the perpendicular component, being more prone to the diffusive effect of scattering, points out differences in the Kernel-Smoother density estimate employed to the principal components, between malignant, normal, and benign tissues. The eigenvectors, corresponding to the dominant eigenvalues of the correlation matrix in SVD, also exhibit significant differences between the three tissue types, which clearly reflects the differences in the spectral correlation behavior. Interestingly, the most significant distinguishing feature manifests in the perpendicular component, corresponding to porphyrin emission range in the cancerous tissue. The fact that perpendicular component is strongly influenced by depolarization, and porphyrin emissions in cancerous tissue has been found to be strongly depolarized, may be the possible cause of the above observation.
Electron microscopy of ribosomal RNA mounted by adsorption in the absence of protein (1975)

Abstract A method is described for visualizing ribosomal RNA in the electron microscope by an adsorption technique. The visual configuration of the molecules is sensitive to the composition of the medium from which they are adsorbed, and is reproducible under a given set of conditions. Regular structural features occur in the larger rRNA species similar to those observed with protein monolayer techniques. The dimensions of adsorbed molecules, however, are more consistent with current models of ribosomal RNA as it exists in solution.
Plant-Derived MINA-05 Inhibits Human Prostate Cancer Proliferation In Vitro and Lymph Node Spread In Vivo (2007)

Few treatment options exist for metastatic prostate cancer (PC) that becomes hormone refractory (HRPC). In vitro, plant-derived MINA-05 caused dose-dependent decreases in cell numbers in HRPC cell lines LNCaP-C4-2B and PC-3, and in androgen-sensitive LNCaP-FGC, DuCaP, and LAPC-4, by WST-1 assay. MINA-05 pretreatment significantly decreased clonogenic survival in agar and on plastic at 1 x and 2 x IC50 for PC-3 (P < .05 and P < .001, respectively), and at 1/2 x, 1 x, and 2 x IC50 for LNCaP-FGC cells (P < .001). MINA-05 also induced G2M arrest of LNCaP-FGC and PC-3 cells (by flow cytometry) and caused some apoptosis in LNCaP-FGC (sub-G1 peak on flow, expression of activated caspase-3) but not in PC-3 cells. Western blotting indicated that these cell cycle changes were associated with decreased levels of regulatory proteins cyclin B1 and cdc25C. MINA-05 given daily by gavage for 39 days did not diminish primary orthotopic PC-3 growth in nude mice, but decreased the extent of lymph node invasion at higher doses. We conclude that MINA-05 induces G2M arrest, inhibits cell growth, reduces PC cell regrowth in vitro, and reduces lymph node invasion after orthotopic PC-3 cell implantation in vivo. It has potential as an adjuvant treatment for patients with PC.
Immunochemical characterization of an autoantigen on platelet glycoprotein IIb in chronic ITP: comparison with the Bak<sup>a</sup> alloantigen (1989)

Employing an immunoblotting procedure, we have identified and characterized an autoantigen carried on glycoprotein (GP) IIb in a patient with chronic idiopathic thrombocytopenic purpura (ITP), and have compared the location of the autoantigen with that of the platelet-specific alloantigen Baka. Immunoblots, using the partially purified GP IIb/IIIa complex as the target antigen, indicated that GP IIb alpha carried both the ITP autoantigen and the Baka alloantigen. The ITP plasma contained another antibody against a 100 kD protein (P100), a trace contaminant in the GP IIb/IIIa sample, which is probably a proteolytic fragment of an internal 124 kD protein. After chymotrypsin treatment, the auto- and alloantigen were found to be located on 65 kD fragments detectable under reducing conditions. In addition, immunoblots made after two-dimensional nonreduced-reduced SDS-polyacrylamide gel electrophoresis (SDS-PAGE) directly demonstrated that both 65 kD fragments had a molecular weight of 80 kD under nonreducing conditions; this provides evidence that these fragments were one and the same, and were derived from GP IIb alpha. Immunoblots of platelets digested in situ with chymotrypsin indicated that the 65 kD fragment of GP IIb alpha was retained by the platelet membrane. We conclude, therefore, that a 65 kD fragment, which represents the membrane side of the chymotrypsin cleavage site on GP IIb alpha, carries a clinically important determinant(s) recognized not only by the anti-Baka alloantibody, but also by the ITP autoantibody.
Survey on hospital patient relationship management in Guangdong Province Traditional Medical Hospital (2007)

Objective: to analyze hospital patient relationship in Guangdong Province Traditional Medical Hospital. Methods: questionnaire, in-depth interview, focus group and participant observation. Control groups were 12 tertiary hospitals. Cross section analysis was made. Results: the effective complaint rate was higher in Guangdong Province Traditional Medical Hospital than control group. Patient loyalty rate was 97% in Guangdong Province Traditional Medical Hospital, higher than control group. Staff had good communication skill and wanted to get cricis prevention training.
The Preparation of Stereoisomeric Alkenyl Lithium Compounds (1951)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe Preparation of Stereoisomeric Alkenyl Lithium CompoundsDavid Y. Curtin and Elbert E. HarrisCite this: J. Am. Chem. Soc. 1951, 73, 6, 2716–2717Publication Date (Print):June 1, 1951Publication History Published online1 May 2002Published inissue 1 June 1951https://pubs.acs.org/doi/10.1021/ja01150a081https://doi.org/10.1021/ja01150a081research-articleACS PublicationsRequest reuse permissionsArticle Views133Altmetric-Citations11LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Pavement Edge Light Safety System, PELSS: Visual Enhancement to Airfield Lighting (2014)

For over 60 years, boundary edge lighting has been limited to a single point of illumination. A taxiway Pavement Edge Light Safety System provides a much needed improvement to the traditional “nodes of light” by adding an illuminated horizontal linear bar that is aligned with the pavement edge. Individual nodes of light can become confusing at night, during reduced visibility periods or when approaching the lights from an angle out of alignment with the runway or taxiway. At larger airports, these lights may appear as a “sea” of random lights which may not provide adequate visual cues for pilots to safely navigate around the airport. The addition of a linear light source to existing taxiway light fixtures, or as a replacement, provides information related to both the location and the orientation of the pavement edge. Rather than time, distance, length and spacing, this paper focuses on patterns that are created once the line segment shape is discernable by the human eye and progress related to a fixture that presents a purposeful illusion of a boundary using a combination of relatively short, elevated, linear light sources.