gebhart/patrepeval huggingface dataset:
Image reconstruction for CT based on compressed sensing and ART (2009)

Algebraic reconstruction technique(ART) is an important method for the image reconstruction of computed tomography(CT),which can recover the image from incomplete projection data.However,ART suffers slow reconstruction speed.An algorithm based on ART is proposed to improve the quality of the recovered image and the speed of reconstruction,making use of the theory of compressed sensing.The algorithm,which combines the gradient sparsity of CT images and ART,performs the projection on the corresponding hyperplane in each iteration, and then adjusts the total variation with the gradient descend method to reduce the l1 norm of the image gradient.The experimental results show the effectiveness of the algorithm.
PROTEIN CROSS-LINKING (1996)

RETURN TO ISSUEPREVNewsNEXTPROTEIN CROSS-LINKINGMAIRIN BRENNANCite this: Chem. Eng. News 1996, 74, 30, 9Publication Date (Print):July 22, 1996Publication History Published online12 November 2010Published inissue 22 July 1996https://pubs.acs.org/doi/10.1021/cen-v074n030.p009https://doi.org/10.1021/cen-v074n030.p009newsACS PublicationsCopyright © 1996 AMERICAN CHEMICAL SOCIETYArticle Views4Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options SUBJECTS:Nucleic acid structure Get e-Alerts
Heart Rate Detection From Plantar Bioimpedance Measurements (2008)

In this paper, a novel technique for heart rate measurement on a standing subject is proposed that relies on electrical impedance variations detected by a plantar interface with booth feet, such as those in some bathroom weighting scales for body composition analysis. Heart-related impedance variations in the legs come from arterial blood circulation and are below 500 mOmega. To detect them, we have implemented a system with a gain in excess of 600, and whose fully differential AC input amplifier has a gain of 4.5 and a common-mode rejection ratio (CMRR) higher than 90 dB at 10 kHz. Differential coherent demodulation based on synchronous sampling yields a signal-to-noise ratio (SNR) of about 54 dB . The system sensitivity is 610 mV/Omega. The technique has been demonstrated on 18 volunteers, whose bioimpedance signal and ECG were simultaneously recorded. A Bland-Altman plot shows a mean bias of -0.2 ms between the RR time intervals obtained from these two signals, which is negligible. The technique is simple and user friendly and does not require any additional sensors or electrodes attached to the body, hence no conductive gel or skin preparation.
Risks and concerns regarding transgenic food and human health Riesgos y preocupaciones sobre los alimentos transgénicos y la salud humana (2002)

<p class="Default" style="text-align: justify;"><span lang="EN-US">The transgenic technology in agriculture has recently been in the center of an intense debate between two radically opposite points of view. Some non-government organizations (NGO) consider this technology as dangerous for human health, environment and economics of developing countries. On the contrary, the scientific community has been publicly supportive of this technology, suggesting that education is the key to gaining the public acceptance. Although genetically modified (GM) plants for food use might have the potential to provide benefits in food quality, nutrition, health and environment, GM plants need additional considerations related with biosafety. Despite there is not evidence that GM foods are more dangerous to human health than conventional food it is necessary to test GM food following the best scientific methodology available. This review focuses on the potential effects that GM food might have on human health. </span> <br><p class="Default" style="text-align: justify;">La tecnología transgénica en la agricultura se ha visto recientemente implicada en un intenso debate entre dos corrientes opuestas. Algunas organizaciones no gubernamentales (ONG) consideran esta tecnología como de alto riesgo para la salud, el ambiente y la economía de los países no desarrollados. Por el contrario, la comunidad científica ha respaldado públicamente esta tecnología asegurando que la clave para su aceptación es la educación. Aunque los alimentos genéticamente modificados (GM) poseen el potencial de proveer beneficios en calidad alimentaria, salud y ambiente, es necesario considerarlos dentro de estrictos protocolos de bioseguridad. No obstante la ausencia de evidencias acerca de que los alimentos transgénicos son más peligrosos para la salud que los alimentos convencionales, aquellos transgénicos deben ser examinados con las metodologías científicas más rigurosas disponibles. Esta revisión se centra en el efecto potencial de los alimentos transgénicos sobre la salud humana.
Absolute stability and spatiotemporal long-range order in Floquet systems (2016)

Recent work has shown that a variety of novel phases of matter arise in periodically driven Floquet systems. Among these are many-body localized phases which spontaneously break global symmetries and exhibit novel multiplets of Floquet eigenstates separated by quantized quasienergies. Here we show that these properties are stable to all weak local deformations of the underlying Floquet drives---including those that explicitly break the defining symmetries---and that the models considered until now occupy submanifolds within these larger ``absolutely stable'' phases. While these absolutely stable phases have no explicit global symmetries, they spontaneously break Hamiltonian-dependent emergent symmetries, and thus continue to exhibit the novel multiplet structure. The multiplet structure in turn encodes characteristic oscillations of the emergent order parameter at multiples of the fundamental period. Altogether these phases exhibit a form of simultaneous long-range order in space and time which is new to quantum systems. We describe how this spatiotemporal order can be detected in experiments involving quenches from a broad class of initial states.
Determination of pyrazon residues in water by reversed phase high performance liquid chromatography (1982)

A simple analytical method is described for the quantitative determination of pyrazon residues in water. It involves high performance liquid chromatography with ultraviolet detection at 270 nm. The procedure is used to determine 2 ppb to 1 ppm levels of pyrazon in water. The traditional liquid-liquid extraction method has been replaced by an adsorption-trapping method for the extraction of pyrazon. Average recovery of pyrazon from the laboratory spiked samples was 98.1%. The method can be used for water samples with concentrations as low as 2 ppb.
Kinesiology of the Hip: A Focus on Muscular Actions (2010)

The 21 muscles that cross the hip provide both triplanar movement and stability between the femur and acetabulum. The primary intent of this clinical commentary is to review and discuss the current understanding of the specific actions of the hip muscles. Analysis of their actions is based primarily on the spatial orientation of the muscles relative to the axes of rotation at the hip. The discussion of muscle actions is organized according to the 3 cardinal planes of motion. Actions are considered from both femoral-on-pelvic and pelvic-on-femoral perspectives, with particular attention to the role of coactivation of trunk muscles. Additional attention is paid to the biomechanical variables that alter the effectiveness, force, and torque of a given muscle action. The role of certain muscles in generating compression force at the hip is also presented. Throughout the commentary, the kinesiology of the muscles of the hip are considered primarily from normal but also pathological perspectives, supplemented with several clinically relevant scenarios. This overview should serve as a foundation for understanding the assessment and treatment of musculoskeletal impairments that involve not only the hip, but also the adjacent low back and knee regions.
The need for champions in rural water supply (1994)

Experiences with rural water supply systems in Finland may provide useful lessons for management in the South.
P16 and <scp>HPV</scp> discordance in metastatic carcinoma of cervical lymph nodes of unknown primary (2015)

The prognostic utility of HPV in oropharyngeal squamous cell carcinoma (OPSCC) and non-OPSCC as has been well documented. Currently, a standardized IHC scoring system does not exist and is needed to define HPV positivity. We have recently seen a patient that provides a caution in using p16 status as a diagnostic aid.
On Optimal Myopic Portfolio Policies, with and Without Serial Correlation of Yields (1971)

Publisher Summary In a recent paper, Mossin attempts to isolate the class of utility functions of terminal wealth, f(x), which, in the sequential portfolio problem, induces myopic utility functions of intermediate wealth positions. Induced utility functions of shortrun wealth are myopic whenever they are independent of yields beyond the current period, that is, they are positive linear transformations of f(x). Mossin concludes that the logarithmic function and the power functions induce completely myopic utility functions, that when the interest rate in each period is zero, all terminal wealth functions such that the risk tolerance index—f’(x)/f”(x) is linear in x induce completely myopic utility functions of short-run wealth, that when interest rates are not zero, the last class of terminal wealth functions induces partially myopic utility functions, and that all of the preceding is true whether the yields in the various periods are serially correlated or not. With the exception of the last assertion, the same conclusions are reached by Leland. The second and third statements are true only in a highly restricted sense even when yields are serially independent and that when investment yields in the various periods are statistically dependent, only the logarithmic function induces utility functions of short-run wealth that are myopic. On optimal myopic portfolio policies, with and without serial correlation of yields in view of the difficulty of estimating future yields and their apparent serial correlation, the myopic property of the logarithmic utility functions is highly significant. However, this function also has other attractive properties.
Serum microRNA expression signatures identified from genome‐wide microRNA profiling serve as novel noninvasive biomarkers for diagnosis and recurrence of bladder cancer (2014)

Recent advantages of serum microRNAs (miRNAs) open a new realm of possibilities for noninvasive diagnosis and prognosis of bladder cancer (BC). The aim of our study was to identify serum miRNA expression signatures in patients with BC and establish new models for the diagnosis of BC and recurrence prediction. We performed genome-wide serum miRNA analysis by Miseq sequencing followed by evaluations in the training and validation sets with reverse transcription quantitative real-time PCR assays from serum samples of 250 patients with BC and 240 controls. A six-miRNA panel (miR-152, miR-148b-3p, miR-3187-3p, miR-15b-5p, miR-27a-3p and miR-30a-5p) for the diagnosis of BC was finally developed by multivariate logistic regression model with an area under the receiver operating characteristic curve of 0.899. The corresponding sensitivities of this panel for Ta, T1 and T2-T4 were 90.00, 84.85 and 89.36%, significantly higher than those of urine cytology, which were 13.33, 30.30 and 44.68%, respectively (all at p<0.001). In addition, Kaplan-Meier analysis showed that patients with nonmuscle-invasive BC (NMIBC) with high miR-152 level and low miR-3187-3p level had worse recurrence-free survival (p=0.023 and 0.043, respectively). In multivariate Cox regression analysis, miR-152 was independently associated with tumor recurrence of NMIBC (p=0.028). Our results suggested that a serum miRNA signature may have considerable clinical value in diagnosing BC. Furthermore, expression level of serum miR-152 could provide information on the recurrence risk of NMIBC.
death counts: the challenge of death and dying in learning disability services (2004)

By talking to people with learning disabilities, their parents and support workers, Stuart Todd has built up a disturbing picture of the way matters surrounding death and dying are handled by our services. They include hiding the truth from service users, disenfranchising bereaved parents, and staff not being allowed to offer the end-of-life care they would like. Here he throws down the challenge for service providers to show more respect to everyone involved in the process of dying
Compact imaging Bragg spectrometer for fusion devices (2004)

A compact imaging x-ray spectrometer has been designed for tokamaks and stellarators to measure the plasma parameters at different spatial chords. It has been optimized for high spectral resolution and high sensitivity. High spectral resolution is obtained by using solid state detectors and minimizing the imaging errors of the spherical crystals. It is shown, that using spherical crystals the solid angle and hence the throughput can be increased significantly, without compromising the spectral resolution. The design is useful for the measurement of the spectra of He- and H-like ions from Si to Kr. The spectral resolution is sufficient for the measurement of plasma parameters. The temporal resolution is high enough for transport studies by gas puff and laser ablation experiments. The design is based on a modified Johann spectrometer mount, utilizing a spherically bent crystal instead of the cylindrically bent crystal in the traditional Johann mount. The astigmatism of the wavelength selective reflection on the spherical crystal is applied to obtain imaging of an extended plasma source on a two-dimensional detector. For each element, a separate crystal is required, only in few cases, a crystal can be used for the spectra of two elements. For the spectra of most of the He-like ions from Si up to Kr, suitable crystal cuts have been found on quartz, silicon and germanium crystals with Bragg angles in a small interval around the design value of 53.5°. All of the crystals have the same radius. They are fixed on a rotational table. The distance to the detector is adjusted by an x–y table to fit to the Rowland circle.
A vueltas con la reforma constitucional del Senado: de las opciones a las decisiones (2006)

I. La representación territorial del
Spirochete antigens persist near cartilage after murine Lyme borreliosis therapy (2012)

An enigmatic feature of Lyme disease is the slow resolution of musculoskeletal symptoms that can continue after treatment, with some patients developing an inflammatory arthritis that becomes refractory to antibiotic therapy. Using intravital microscopy and the mouse model of Lyme borreliosis, we observed that Borrelia burgdorferi antigens, but not infectious spirochetes, can remain adjacent to cartilage for extended periods after antibiotic treatment. B. burgdorferi was not recovered by culture or xenodiagnosis with ticks after antibiotic treatment of WT mice and all but one of the immunodeficient mice with heightened pathogen burden due to impaired TLR responsiveness. Amorphous GFP+ deposits were visualized by intravital microscopy in the entheses of antibiotic-treated mice infected with GFP-expressing spirochetes and on the ear cartilage surface in sites where immunofluorescence staining detected spirochete antigens. Naive mice were not infected by tissue transplants from antibiotic-treated mice even though transplants contained spirochete DNA. Tissue homogenates from antibiotic-treated mice induced IgG reactive with B. burgdorferi antigens after immunization of naive mice and stimulated TNF-α production from macrophages in vitro. This is the first direct demonstration that inflammatory B. burgdorferi components can persist near cartilaginous tissue after treatment for Lyme disease. We propose that these deposits could contribute to the development of antibiotic-refractory Lyme arthritis.
Prostaglandin F2 alpha stimulates transforming growth factor-alpha expression in adipocyte precursors (1995)

Transforming growth factor-alpha (TGF alpha) and prostaglandin F2 alpha (PGF2 alpha) are potent inhibitors of adipocyte differentiation. We demonstrate here that TGF alpha messenger RNA (mRNA) is expressed in freshly isolated fat pads and in primary culture of adipocyte precursors cultivated in defined medium before and after differentiation. We show that PGF2 alpha stimulated TGF alpha mRNA expression in a dose-dependent manner. PGF2 alpha also stimulated TGF alpha production in the culture medium of adipocyte precursors in primary culture. PGF2 alpha stimulated TGF alpha mRNA expression in both undifferentiated and differentiated cells. 9 alpha,11 beta-PGF2 alpha, which also inhibited adipose differentiation, stimulated TGF alpha mRNA expression similarly to PGF2 alpha, whereas other PGs had no effect on TGF alpha mRNA expression. The time-course experiment indicates that the stimulation of TGF alpha mRNA expression by PGF2 alpha is observed within 6 h of exposure to PGF2 alpha and is inhibited by treatment of the cells with actinomycin D. The effect of PGF2 alpha on TGF alpha expression did not require activation of protein kinase C and was fully reversible. As both TGF alpha and PGF2 alpha are inhibitors of adipose differentiation, it is suggested that stimulation of TGF alpha expression by PGF2 alpha could represent an amplification mechanism to modulate adipocyte precursor differentiation and adipocyte function within the adipose tissue.
The pulmonary clearance of bacteria by calves and mice. (1972)

Using a modified aerosol generator, white mice and calves were exposed to aerosols of viable Staphylococcus aureus and Pasteurella haemolytica and the clearance of the inhaled organisms by the lungs of the experimental animals was measured. Fifty-seven percent of inhaled S. aureus were cleared in two hours by the mouse lungs, 79% were cleared in four hours and 93% were cleared in eight hours. Fifty-six percent of inhaled P. haemolytica were cleared in two hours by the mouse lungs, 76% were cleared in four hours and 93% were cleared in eight hours. Seventy percent of inhaled S. aureus were cleared in two hours by the calf lungs, 90% were cleared in four hours and 95% were cleared in eight hours. Seventy-five percent of inhaled P.haemolytica were cleared in two hours by the calf lungs, 90% were cleared in four hours and 92% were cleared in eight hours.
Molecular Cloning and Characterization of Viruses Isolated from Chimpanzees with Pathogenic Human Immunodeficiency Virus Type 1 Infections (1998)

We have previously described the development of AIDS in a chimpanzee (C499) infected with human immunodeficiency virus type 1 (HIV-1) and the subsequent pathogenic HIV-1 infection in another chimpanzee (C455) transfused with blood from C499 (F. J. Novembre et al., J. Virol. 71:4086-4091, 1997). In the present study, two virus isolates were derived from these animals: HIV-1JC from peripheral blood mononuclear cells (PBMC) of C499, and HIV-1NC from plasma of C455. These virus isolates were used to generate two infectious molecular clones, termed HIV-1JC16 and HIV-1NC7 (JC16 and NC7, respectively). Comparative analyses of the sequences of the two clones showed that they were highly interrelated but distinct. Based on heteroduplex mobility assays, JC16 and NC7 appear to represent dominant viruses in the uncloned stock population. Compared with amino acid sequences of the parental viruses HIV-1SF2, HIV-1LAV-1b, and HIV-1NDK, JC16 and NC7 showed a number of differences, including insertions, deletions, and point mutations spread throughout the genome. However, insertion/deletion footprints in several genes of both JC16 and NC7 suggested that recombination between SF2 and LAV-1b could have occurred, possibly contributing to the generation of a pathogenic virus. Comparative in vitro analyses of the molecular clones and the uncloned stocks of HIV-1JC and HIV-1NC revealed that these viruses had strikingly similar replicative abilities in mitogen-stimulated PBMC and in macrophages. Compared to the SF2 and LAV-1b isolates of HIV-1, HIV-1JC and HIV-1NC isolates were more similar to LAV-1b with respect to the ability to replicate in mitogen-stimulated PBMC and macrophages. These viruses should prove to be useful in mapping determinants of pathogenesis.
Efficacy and limitations of an ATP-based monitoring system. (2010)

Monitoring of sanitation is an essential function of laboratory animal facilities. The purpose of the current study was to assess the ability of an ATP-based system to detect microbes and organic contaminants. Serial dilutions of Escherichia coli, Staphylococcus aureus, Toxocara canis eggs, Toxoplasma gondii tachyzoites, epithelial cells, and rodent blood, urine, and feces were analyzed according to the manufacturer's recommendations. The limit of E. coli detection was 10(4) organisms; sonication of E. coli significantly improved detection, indicating incomplete bacterial lysis in the detection system. Detection of S. aureus was significantly greater than that of E. coli with a limit of detection of 10(2); sonication did not alter results. In contrast, detection of T. canis, T. gondii, RBC, and epithelial cells was robust and ranged from 2 T. canis eggs to 10 epithelial cells. Urine was weakly detected, with a limit of detection at 1:10 dilution. Detection of all cell types except epithelia had a strong linear correlation to total cell number. In addition, our data demonstrate that the efficacy of the detection system can be affected adversely by residual disinfectants and that sample-bearing swabs are stable for more than 7 h after swabbing. These data demonstrate that this ATP based system sensitively detects pure cells and organic contaminants with a strong degree of linear predictability. A limitation of the system is its inability to detect gram-negative bacteria efficiently because of incomplete cell lysis.