gebhart/patrepeval huggingface dataset:
A pharmacokinetic comparison of murine and chimeric forms of the 99mTc-labelled 174H.64 monoclonal antibody. (1994)

The monoclonal antibody (MoAb) 174H.64 (Truscint SQ, Biomira Inc.) is a murine-derived MoAb reacting with an extracellular surface component of the cytoskeletal matrix ectopically expressed on squamous-cell carcinoma cell-surface membranes. A chimeric form of this MoAb has also been produced by genetically modifying the Fc portion of the MoAb by the insertion of a human Fc fragment. During this process the isotype was altered from an IgG1 (murine) to an IgG3 (chimeric). Pilot and phase I/II clinical trials of the murine and chimeric 99mTc-labelled 174H.64 MoAbs have been undertaken at selected European and North American sites. As part of this evaluation serum, urine and image data were collected at specific time intervals and used to obtain a kinetic model to describe the in vivo distribution of the MoAbs. A two-compartment model of the form: C(t) = C1 e-lambda 1t + Cz e-lambda zt was found to best describe the serum distribution of radioactivity of both the murine and chimeric MoAbs. The initial distribution half-lives were 2.9 +/- 0.7 hours and 2.7 +/- 0.2 hours, and the terminal elimination half-lives were 17.6 +/- 3.8 hours and 22.5 +/- 1.3 hours for the murine and chimeric MoAbs, respectively. No significant difference was found between the kinetic model parameters of two MoAbs at the 95% level. Assuming a similar clinical efficacy, these MoAbs could then be used interchangeably, with the chimeric MoAb offering potential advantages in reducing HAMA response.
The grape berry-specific basic helix–loop–helix transcription factor VvCEB1 affects cell size (2013)

The development of fleshy fruits involves complex physiological and biochemical changes. After fertilization, fruit growth usually begins with cell division, continues with both cell division and expansion, allowing fruit set to occur, and ends with cell expansion only. In spite of the economical importance of grapevine, the molecular mechanisms controlling berry growth are not fully understood. The present work identified and characterized Vitis vinifera cell elongation bHLH protein (VvCEB1), a basic helix-loop-helix (bHLH) transcription factor controlling cell expansion in grape. VvCEB1 was expressed specifically in berry-expanding tissues with a maximum around veraison. The study of VvCEB1 promoter activity in tomato confirmed its specific fruit expression during the expansion phase. Overexpression of VvCEB1 in grape embryos showed that this protein stimulates cell expansion and affects the expression of genes involved in cell expansion, including genes of auxin metabolism and signalling. Taken together, these data show that VvCEB1 is a fruit-specific bHLH transcription factor involved in grape berry development.
Uncertainty History Matching and Forecasting, a Field Case Application (2012)

Abstract Geological, reservoir, economical and technological uncertainties have an effect on decision making and consequently on reserves development plans. Quantifying the impact of these uncertainties can make this process more reliable. A great difficulty to achieve this in practice is the variability and complexity of workflows available to manage uncertainty using numerical simulation. The inaccuracy, high uncertainty or lack of reliable data yields risk to the forecasting process, making the calibration of the dynamical model with the field production data indispensable. History matching is an inverse problem and, in general, different combinations of reservoir attributes can lead to acceptable solutions, especially due to the high degree of uncertainty of these attributes. A set of solutions that respect the observed data may lead to different prediction scenarios. The objective of this work is the integration of history matching with probabilistic analysis of representative scenarios. A methodology that allows the recognition of well-calibrated models within an acceptable deviation is used. This procedure helps to identify the critical uncertain parameters and their possible variation in order to estimate the representative reserve range. The goal is not to find the best deterministic match, but rather to show how the calibration process allows a mitigation of identified uncertainties. A real case based on a reservoir from Campos Basin in Brazil was used. A 14 year historical period followed by a 12 year forecast period was considered, allowing verification and validation, at a global level, of the proposed procedure in a complex dynamic model. Two different commercial softwares were used, in order to demonstrate the advantages and restrictions of each approach. Distribution variations of the responses in time were evaluated by Latin Hypercube sampling and Monte Carlo propagation on validated proxy models. The proposed methodology allows: (1) to reduce the range of possible models taking into account the observed data; (2) to identify the existent uncertainty as a function of observed data; (3) to reduce the uncertainty range of critical reservoir parameters; (4) to increase confidence in production forecast. One contribution of this work is to present a quantitative approach for increasing the reliability of reservoir simulation as an auxiliary tool in decision making processes in order to reduce the associates risk and to maximize development opportunities.
Domain wall encoding of integer variables for quantum annealing and QAOA [dataset] (2019)

All of the data from the paper, as well as an easy python module or creating domain wall encodings. Marked as software, even though it also does contain the datasets.
VLSI design of a reconfigurable multi-mode Reed-Solomon codec for high-speed communication systems (2003)

This paper presents the VLSI design of a reconfigurable multimode Reed Solomon (RS) codec for various high-speed communication systems. Our decoder design is based on the Euclidean algorithm such that the datapath units are regular and simple. With its ability to support a variety of (n, k, t) RS specifications (0/spl les/t/spl les/8) and (0/spl les/n/spl les/255), this RS codec design is suitable for multi-mode systems such as the xDSL and the cable modem systems. The chip operates at a clock frequency of 100 MHz and has a data processing rate of 800 Mbits/s in 0.35 /spl mu/m CMOS technology at the supply voltage of 3.3 V. The total gate count is 34,647 gates and the core size is only 1,578 /spl times/ 1,560 /spl mu/m/sup 2/.
MRI directed bilateral stimulation of the subthalamic nucleus in patients with Parkinson's disease (2003)

An MRI directed targeting method for implantation of DBS leads into the STN can be used safely and effectively, and results are comparable with studies using intraoperative microelectrode neurophysiological targeting. In addition, our method was associated with an efficient use of operating time, and without the necessary costs of microelectrode recording.
A novel accelerometer for sensing pen tip motion (1998)

An accelerometer for sensing pen tip motion has been designed, fabricated and tested. The sensor takes the form of a complex pendulum with four suspension arms of diameter 50μm and length 50mm attached to the comers of a 3mm square proof mass of 10 -8 kg. Initial assessment of the device indicates that it is robust to production process variations and has a sensitivity significantly better than 0.02m/s 2 .
Commercial Aircraft Exterior Cleaning Optimization (2009)

The time interval between aircraft exterior cleaning has traditionally been based upon experience and maintenance patterns rather than scientific reasoning. Therefore, the relationship between skin friction drag, aircraft exterior cleaning intervals, and fuel consumption has never been fully established or understood by airline operators. This work represents an attempt to investigate the effects of subtle changes in surface roughness on skin friction drag. Experiments were set up using several differently roughened surfaces. The results were analyzed and compared to a smooth reference surface which showed a clear correlation between skin friction drag with surface roughness. Surface roughness was reduced by approximately one-third as a result of aircraft washing in measurements taken from a sample of commercial aircraft. Using regression analysis of the surface measurements and relationships established in the experimentation, an optimum time interval between aircraft exterior cleaning was found. The optimum time frames recommended weighed the effects of the aerodynamic deterioration, due to surface roughness, against the costs involved in cleaning an aircraft. As a result a time interval between aircraft cleaning that maintains aerodynamic efficiency and cost practicality was achieved.
The extended MENT algorithm: a maximum entropy type algorithm using prior knowledge for computerized tomography (1991)

Unlike MENT (maximum entropy algorithm), the extended MENT algorithm can process prior information and deal with incomplete projections or limited angle data. The reconstruction problem is formulated for solving linear systems involving the Fredholm integral equation. To develop the extended MENT algorithm, maximum entropy is substituted by a more general optimization criterion, that of minimizing the discriminatory function. The a priori knowledge of the shape of the object is easily incorporated in the algorithm by using the discriminatory function. Useful mathematical properties that make the discriminatory function attractive are derived. The sensitivity of the minimum discriminatory solution is derived to determine the characteristics of the noise in the reconstructed images. The extended MENT algorithm is developed for a parallel geometry, and its convergence properties are given. Its image processing performance is better than that for other maximum entropy algorithms such as multiplicative algebraic reconstruction techniques (MART) or more standard methods such as ART and the convolution backprojection.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Understanding human-place interaction from tracking and identification of many users (2013)

This paper considers the problem of understanding human-place interaction, such as relationships among many users in a space and interactions between users and their surroundings, from trajectories of users in a common space. The discovered information can be applied to provide a number of services. For example, we can determine the optimal arrangement of items in a store or at an exhibition to maximize the profit or attention and systematically manage the pedestrian traffic. Users in a space is detected and tracked by a vision-based multi-target tracking algorithm and trajectories of users are identified by combining visual information and accelerometer readings from users' smartphones. We demonstrate that trajectories of users can be used to reveal a number of useful information about the users and the space, such as spatial occupancy of individual users, intimacy between users, objects of interests, and a common interest of users.
Privacy Codes of Practice for the Social Web: The Analysis of Existing Privacy Codes and Emerging Social-Centric Privacy Risks (2010)

Privacy codes of practice developed in the 1980s in response to the concerns about the introduction of computerized databases, automated personal information processing systems, and easy transmission of personal information across national and international boundaries. The current data-practice guidelines, laws, and model-codes have been modeled based on these early codes. Starting from the early 2000, the socialization of the Web introduced a new kind of private information flow model and new privacy risks. In this paper, we analyzes the core principles of existing privacy codes with respect to emerging social-centric privacy risks. Our major contribution in this work is twofold. Legally - this evaluation is useful to enhance current privacy codes for the Social Web. Technically - this evaluation is useful to design the future social-centric privacy policy languages and their data handling specifications.
Full-Subtopic Retrieval with Keyphrase-Based Search Results Clustering (2009)

We consider the problem of retrieving multiple documents relevant to the single subtopics of a given web query, termed "full-subtopic retrieval". To solve this problem we present a novel search results clustering algorithm that generates clusters labeled by keyphrases. The keyphrases are extracted from the generalized suffix tree built from the search results and merged through an improved hierarchical agglomerative clustering procedure. We also introduce a novel measure for evaluating full-subtopic retrieval performance, namely "Subtopic Search Length under k document sufficiency". Using a test collection specifically designed for evaluating subtopic retrieval, we found that our algorithm outperformed both other existing search results clustering algorithms and also a search results re-ranking method that emphasized diversity of results (at least for k≫1; i.e., when we are interested in retrieving more than one relevant document per subtopic). Our approach has been implemented into KeySRC (Keyphrase-based Search Results Clustering), a full web clustering engine available online at http://keysrc.fub.it.
Traditional pest management practices in Kanyakumari district, southern peninsular India (2006)

S Kiruba, B P Mishra, S Israel Stalin, S Jeeva 4 & S Sam Manohar Dhas* Department of PG Studies and Research Centre in Zoology, Scott Christian College, Nagercoil 629 003, Tamil Nadu E-mail: sam_biocontrol@yahoo.com Ecology Research Laboratory, Department of Botany, School of Life Sciences, North – Eastern Hill University, Mawlai Umshing Mawkynroh, Shillong 793 022, Meghalaya Department of PG Studies and Research Centre in Botany, Scott Christian College, Nagercoil 629 003, Tamil Nadu Department of PG Studies and Research Centre in Botany, Virudhunagar Hindu Nadars’ Senthikumara Nadar College, Virudhunagar 626 001, Tamil Nadu
[Effects of physical activity on cognitive functions, balance and risk of falls in elderly patients with Alzheimer's dementia]. (2010)

Physical activity may be an important non-pharmacological approach that can benefit cognitive functions and balance and reduce the risk of falls. Moreover, agility and balance are associated with cognitive functions in elderly patients with AD.
Mathematical thinking through different representations and analogy (2011)

Mathematical thinking is a core element in mathematics education and classroom learning. This paper wish to investigate how primary four (grade 4) students develop their mathematical thinking through working on tasks in multiplication where greatest products of multiplication are required. The tasks include the format of many digit times one digit, 2 digits times 2 digits up to 3 digits times 3 digits. It is found that the process of mathematical thinking of students depends on their own representation in obtaining the product. And the solution is obtained through a pattern/analogy and pattern plus process. This specific learning process provides data for understanding structure and mapping in problem solving. The result shows that analogy allows successful extension of solution structure in the tasks.
Los derechos políticos en el Sistema Interamericano de Derechos Humanos (2011)

espanolEl presente articulo desarrolla los criterios elaborados en las sentencias y opiniones consultivas de la Corte Interamericana de Derechos Humanos y en los informes de la Comision Interamericana de Derechos Humanos, respecto de la proteccion de los derechos politicos tal como se encuentran contemplados en la Convencion Americana de Derechos Humanos. Ha resaltado el pnud en su informe sobre �La democracia en America Latina� (2004) que Asistimos a una ampliacion en el alcance de los derechos politicos, por un lado para integrar otros derechos en el paraguas de un derecho mas general y medular a la democracia: el derecho a la participacion politica y por el otro, la ampliacion ciudadana producto de los procesos de integracion supranacionales. En este contexto, en el Sistema Interamericano de Derechos Humanos, los precedentes de la Corte Interamericana, principalmente los casos Yatama vs. Nicaragua del ano 2005 y Castaneda Gutman vs. Estados Unidos Mexicanos de 2008, profundizan los desarrollos juridicos del sistema en materia de derechos politicos. EnglishThe present article develops the criteria prepared in the judgments and advisory opinions of the Inter-American Court of Human Rights, with regard to the protection of the political rights as they are contemplated in the American Convention of Human Rights. The pnud has highlighted in his report on �The democracy in Latin America� (2004) that �[...] the democracy does not come down to the electoral act but it needs from efficiency, transparence and equity in the public institutions, as well as of a culture that should accept the legitimacy of the political opposition and recognizes, and abigue for, the rights of all�. Since �the democracy exceeds to a method to choose those who govern, it is also a way of constructing, of guaranteeing and of expanding the freedom, the justice and the progress, organizing the tensions and the conflicts that generate the struggles of power�. We are present at an enlargement in the scope of the political rights, on the one hand to integrate other rights in the most general aspect of a right and fundamental to the democracy: the right to the political participation and on the other side, the civil enlargement product of the supranational processes of integration. In this context, in the Inter-American System of Human rights, the precedents of the Inter-American Court, principally the cases Yatama vs. Nicaragua of the year 2005 and Castaneda Gutman vs. The Mexican United States of the year 2008, deepen the juridical developments of the system on the subject of political rights.
Advanced Base Isolation Systems for Light Weight Equipments (2012)

This chapter is intended to introduce the earthquake proof technology particularly in the area of base isolation systems that have been used to protect light weight structures, such as motion sensitive equipment, historic treasures, and medical instruments, etc., from earthquake damage. This chapter presents theoretical background, experimental studies, numerical analyses, and the applications of the advanced isolation systems consisting of rolling-and sliding-type isolation systems for light weight structures. The efficiency of these isolators in reducing the seismic responses of light weight equipment was also investigated in this study. In addition, the results from theoretical and experimental studies for these isolators are compared and discussed.
Photomixing of achromatically frequency-modulated incoherent light (1993)

Temporally incoherent white light has been frequency modulated achromatically so that in photomixing relatively narrow-band frequency-modulated spectra have been observed. This achromatic frequency modulation can be obtained by the use of a balanced grating interferometer with audio or rf modulation of the vertex grating.
[Acute symmetric polygangrene of the extremities]. (1983)

The authors stress the importance, in acute symmetric polygangrene of the extremities, of systemic disease accompanied by decreased perfusion with its physicochemical consequences on parietal structures and the liquid contents of vessels and tissues developing rapidly in the extremities. In the first chapter, they recall the various aetiologies proposed in the literature. They then describe 3 personal case studies which they have chosen for their extreme age range and their varying aetiology. They present the various pathogenic factors which can occur either in isolation or in combination: parietal factors, abnormalities of the various elements of the blood, plasma factors, all of which are responsible for rheological disturbances which, when combined with decreased perfusion, lead to the development of gangrene. Finally, they present their ideas about treatment which sould be a function of the aetiology and the stage of the disease at the time of diagnosis.
Access control mechanisms in a distributed, persistent memory system (2002)

A distributed, persistent memory system is considered, which implements a form of segmentation with paging within the framework of the single-address-space paradigm of memory reference. A peculiar problem of a system of this type is the lack of protection of the private information items of any given process against unauthorized access attempts possibly performed by the other processes. We present a set of mechanisms able to enforce access control over the private virtual space areas. These mechanisms guarantee a degree of protection comparable to that typical of a multiple-address-space system, while preserving the advantages of ease of information sharing, typical of the single-address-space model. The resulting environment is evaluated from a number of salient viewpoints, including ease of distribution and revocation of access rights, strategies for virtual space reuse, and the storage requirements of the information for memory management.
Sarcocystis OF PASSERINE BIRDS: SEXUAL STAGES IN THE OPOSSUM (Didelphis virginiana) (1980)

Sexual stages of a Sarcocystis of passerine birds were demonstrated by feeding muscle cysts from cowbirds (Molothrus ater) and grackles (Cassidix mexicanus) to opossums (Didelphis virginiana). Opossums were examined at necropsy at 36 h, 13.5 days, and 29.5 days post-inoculation (PI). Large numbers of macro- and microgamonts were present in the small intestine 36 h PI, while only sporocysts and oocysts were present 13 days or more PI. Microgamonts in different stages of development were in the intestinal epithelium above the nucleus and macrogamonts were at the base of the epithelial cells or in the lamina propria. Oocysts and sporocysts were in the core of villus, beneath the basement membrane. Descriptions are given of the sexual stages as they appear in sections and smears.
High-performance ripple feedback for the buck unity-power-factor rectifier (2002)

The buck unity power factor rectifier has harmonic-free input current with complete load regulation down to zero output voltage. A new "nonlinear ripple feedback" is proposed which exactly cancels the spoiling effect of DC-side current ripple on the low-distortion AC line current waveforms, even for large amounts of ripple. This cancellation is independent of operating point and readily implemented with analog hardware, thereby permitting economies in the design of the DC filter while maintaining harmonic-free operation. Both large-signal and incremental analyses of the rectifier are given. Confirming experimental results from a 1 kW 48 V isolated battery charger operating with current-ripple levels ranging from 50 percent to discontinuous-conduction-mode operation are given.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>