gebhart/patrepeval huggingface dataset:
Immature Platelet Fraction bei Neugeborenen mit Sepsis oder NEC (2010)

Hintergrund Sepsis und nekrotisierende Enterokolitis (NEC) sind die häufigsten Ursachen der schweren Thrombozytopenie auf einer Neugeborenen-Intensivstation. Während des Krankheitsverlaufs fiel es bisher schwer, die Aktivität der Megakaryopoiese des Knochenmarks einzuschätzen. Die retikulierten Thrombozyten im peripheren Blut sind das Analogon der Retikulozyten und eignen sich, eine Produktionsstörung von einem Verbrauch der Thrombozyten zu unterscheiden. Als immature platelet fraction (IPF) können diese voll-automatisch im Durchflusszytometer gemessen werden. Fragestellung Bestimmung der Plättchenproduktion anhand serieller Messung der IPF bei Neugeborenen (NG) mit Sepsis oder NEC. Methode Einschlusskriterium: NG mit mikrobiologisch bestätigter Sepsis (positive Blutkultur) oder NEC (mit Darmoperation). Messung der Thrombozytenzahl und der IPF an drei Zeitpunkten: T0=vor Auftreten der Sepsis/NEC; T1=Diagnose der Sepsis/NEC; T2=Nadir der Thrombozytenzahl. Statistische Analyse: ANOVA oder Fisher-Exact-Test. Ergebnisse Es wurden insgesamt 38 Patienten eingeschlossen (28 Sepsis, 10 NEC). 20 (53%) Patienten zeigten eine Thrombozytopenie (<150/nl);12 (29%) Patienten zeigten eine schwere Thrombozytopenie (<50/nl) zum Zeitpunkt T2. 10 (26%) der Patienten erhielten eine Thrombozytentransfusion. Die Thrombozytopenie in der NEC-Gruppe war signifikant häufiger (9 von 10 Patienten) als in der Sepsis-Gruppe (11 von 28 Patienten, p<0,01). In der NEC-Gruppe war die mittlere Thrombozytenzahl (94±117/nl) an T2 im Vergleich zur Sepsis-Gruppe signifikant niedriger (184±109/nl; p<0,001). Parallel zum Abfall der Thrombozyten von T0 zu T2 kam es in beiden Gruppen zu einem Abfall der IPF (T0=20±13/nl; T2=14±10/nl; p<0,05). Im Falle einer Thrombozytopenie fiel die IPF von T0 (20±13/nl) zu T2 (9±8/nl; p<0,01). Obwohl die Thrombozytopenie bei der NEC zum Zeitpunkt T2 ausgeprägter war, unterschied sich die IPF zwischen den Gruppen nicht. Betrachtete man nur die Patienten mit einer Thrombozytopenie, fällt ein Trend zur höheren IPF in der NEC Gruppe (11±9/nl) im Vergleich zur Sepsis-Gruppe (7±5/nl) auf. Diskussion Wie erwartet, ist die Thrombozytopenie bei der NEC häufiger und schwerer als bei der Sepsis. Allerdings ist dies nicht auf eine verringerte Thrombozytenproduktion zurückzuführen. Ursächlich für die schwere Thrombozytopenie bei der NEC scheint der stärkere Verbrauch an Thrombozyten im Vergleich zur Sepsis zu sein. Insgesamt fällt auf, dass zum Zeitpunkt des Nadirs der Thrombozytenzahl die Thrombozytenproduktion in beiden Gruppen auf die Hälfte abgefallen ist, sich allerdings auf einem Niveau befindet, welches weit oberhalb von Patienten mit Knochenmarksdepression nach Chemotherapie befindet (IPF 0,7/nl). Schlussfolgerung IPF ist ein geeigneter Marker, die Megakaryopoiese zu evaluieren, und zeigt bei NG mit Sepsis/NEC eine auf die Hälfte reduzierte Thrombozytenproduktion an.
Intelligent-Illumination STED (2017)

Recently established fluorescence superresolution microscopy techniques, such as\nstimulated emission depletion (STED), are capable of imaging fixed and living\ncells at the nanometer scale. In STED, ON- and OFF-switching of fluorophores\nis performed with an excitation and a STED laser beam, respectively. During each\nswitching cycle a finite probability exists that the fluorophore is photobleached. This\nhampers the possible STED resolution and sample structure definition.\nIn this thesis, the connection between photobleaching, the obtainable fluorescence\nsignal and the STED resolution was investigated. It was found that the maximum\nfluorescence signal extractable from a sample is inversely proportional to the\nSTED resolution increase to the power of four. As a reverse conclusion, a higher\nfluorescence signal will always facilitate a better STED resolution and sample\nstructure representation.\nTo achieve such higher signals, a STED microscope was built which uses a spatial\nlight modulator (SLM) as the phase mask element for the OFF-switching pattern\ncreation. Especially under live-cell conditions, and at great sample depths, the SLM\nhas conceptual advantages compared to conventional elements.\nTo push the maximum fluorescence signal and resolution further, novel intelligentillumination\nscan schemata were developed. Those locally reduce photobleaching\nin the sample. The MINFIELD scan scheme (sub-diffraction sized scan fields of\n~ 50−200 nm) was realized with 2D- and 3D-STED using intelligent beam control,\nleading to a simple microscope design with a great application range.\nThe novel illumination scheme, Dynamic intensity MINimum (DyMIN), combines\nthe advantages of MINFIELD and of the sample responsive illumination concept\nRESCue. With DyMIN, just as little OFF-switching intensity is applied to the\ncurrent sample structure to have a clear ON/OFF-separation of the fluorophores.\nThe typically much lower light dose provides a superior bleaching reduction for a\nlarge scan field. With 2D- and 3D-STED DyMIN scanning, a reduction of the light\ndose acting directly on the fluorophores up to 20-fold was possible, and the overall\nillumination of the sample was lowered more than 100-fold for sparser samples, both\ncompared to a similar conventional scan. DyMIN enabled the best ever reported\nSTED resolutions for a large field of view, ~ 17nm in the lateral direction, and\n~ 34nm in the axial direction.\nI
[Prostate cancer]. (1999)

Although the incidence of latent or incidental cancer of the prostate is quite similar among Japanese and Americans, the incidence of clinically manifest prostate cancer and the mortality rates of prostate cancer are significantly higher in the latter. But, recently, the incidence of clinical cancer in Japan has been increasing exponentially, and the change in dietary habits is considered to be a major cause of this increase. Comparing the histological differences of prostate cancer between the Japanese and the Americans, the cribriform pattern is predominant in Japanese clinically significant cancer. On the other hand, a simple glandular pattern is predominant in American clinically significant cancer. These differences between Japanese and American prostate cancer suggest that each prostate cancer arises from different sources. For the organ-confined prostate cancer (stage A2 and B); radical prostatectomy has been considered the definitive treatment. But radiotherapy is now considered another radical treatment for localized prostate cancer which results in reduced morbidity. A heavy particle beam and brachytherapy are an even more radical modality that can deliver a greater dose of radiation to a localized lesion without affecting the surrounding normal tissue. For locally advanced prostate cancer (stage C); For the purpose of downstaging and radical treatment of locally advanced prostate cancer, combination of neoadjuvant hormonal therapy and radical prostatectomy has been expected. This regimen resulted in a significant decrease of positive surgical margins, but did not result in decrease of PSA failure. The impact on patient survival will be determined by the long-term follow-up. For advanced prostate cancer (stage D); In the study of the comparison of bilateral orchiectomy with or without flutamide in stage D2 prostate cancer, neither significant improvement of combination group on progression-free survival nor overall survival has been shown. From this result, the true efficacy of MAB is not certain.
The Skipper Butterﬂies (Hesperiidae) of Trinidad Part 16, Hesperiinae, Genera Group J, Vettius – Naevolus (2009)

Trinidad skippers of the genera Vettius , Turesis , Thoon , Justinia , Eutychide , Onophas and Naevolus (Evans’ Genera Group J; Moncini (part)) are treated. Details are given of the taxonomy, history, description, identiﬁcation and biology of the 12 Trinidad species in these genera. Of these, only one species, Vettius fantasos (Stoll), occurs in Tobago. Adults of all species are illustrated, as are the male genitalia of Vettius tertianus (Herrich-Schaffer), Eutychide complana (Herrich- Schaffer) and E. subcordata subcordata (Herrich-Schaffer). The life histories of Vettius phyllus phyllus (Cramer) (from Colombian material), Justinia justinianus hyperythrus (Kaye), and E. s. subcordata are described and illustrated. Key words: Trinidad, Hesperiidae, Vettius , Turesis , Thoon , Justinia , Eutychide , Onophas, Naevolus, life history.
Spiroaminobarbituric Acids. I<sup>1</sup> (1959)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSpiroaminobarbituric Acids. I1James A. Stanfield and Phillip M. DaughertyCite this: J. Am. Chem. Soc. 1959, 81, 19, 5167–5171Publication Date (Print):October 1, 1959Publication History Published online1 May 2002Published inissue 1 October 1959https://pubs.acs.org/doi/10.1021/ja01528a037https://doi.org/10.1021/ja01528a037research-articleACS PublicationsRequest reuse permissionsArticle Views126Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Swan, Trevor W. (1914–1989) (2008)

The first professor of economics at the Australian National University, Trevor W. Swan was an Australian economist known for his foundational contributions to economic growth theory and the theory of economic policy in small open economies. Independently, he and Robert Solow simultaneously formulated what has become known as the Solow–Swan model of economic growth. He devised ‘the Swan diagram’ familiar to generations of students of international economics. A graduate of the University of Sydney, Swan became an Officer of the Order of Australia in 1988 ‘for service to education and to government particularly in the field of economics’.
A Low Phase-Noise 9-GHz CMOS Quadrature-VCO using Novel Source-Follower Coupling Technique (2007)

A 9-GHz quadrature voltage-controlled oscillator (QVCO) with an improvement of 1/f noise performance due to the use of proposed source-follower coupling technique is presented. In contrast to conventional parallel or series coupling methods by which the coupling transistors are operated in saturation region, the source-follower coupling technique, which uses a coupling transistor operated in cut-off region, is invented. Therefore, 1/f noise is much lower than that of the conventional topologies due to the less turn-on duty cycle of the coupling-transistor than that of conventional one, which in turns results in smaller phase noise. It is found experimentally that the phase noise of the QVCO can be reduced by more than 8 dB due to the suppression the 1/f noise of coupling transistor by changing its operation condition from saturation to cut-off region. This QVCO achieves a phase noise of -115 dBc/Hz at 1-MHz-offset away from the 9.17 GHz carrier, corresponding to a figure-of-merit (FOM) of -183.4 dBc/Hz.
Charging of SAML-based federated VoIP services (2010)

Whilst SAML-based federations are most often used by\nacademic and semi-commercial institutions that focus only\non attribute-based authentication, we foresee a growing\ninterest for service providers providing charged services.\nSince more and more academic and semi-commercial federation\nparticipants offer Voice-over-IP (VoIP) services, this\ntype of service provides an entry point into identity federation based payment. Therefore, this paper describes an\napproach on how to harmonize the SAML-based federation\ntechnology with the needs of a payment infrastructure\nfor enabling charging of VoIP services within a federation.\nHowever, since the different aspects of our approach (SAML\nPayment, SIP Discovery and Tariff Function) are not bound\nto VoIP applications, each one of them could be used separately or combined for several service types.
Diaspora and the Politics of Authenticity (2004)

Songs such as 'The Wild Colonial Boy', 'Carmina Burana' and several jazz songs are considered to highlight the place of diaspora music in Australian culture. This type of music involved an integration of local features to recreate an adapted version of authentic source materials.
Near infrared photon migration optic probe for improving breast core needle biopsy (2004)

We have developed a near infrared photon migration fiber optic probe which can be inserted into bore of a breast core biopsy needle, enabling preliminary diagnosis of breast lesions before they are removed.
MAP-DFE Detector for Downlink V-BLAST MC-CDMA Systems (2006)

In this paper, multi-user detection (MUD) techniques are investigated for multiple input multiple output multi- carrier code division multiple access (MIMO MC-CDMA) systems. maximum a posteriori decision feedback equalizer (MAP-DFE) already introduced in MIMO systems is extended to the MC-CDMA downlink transmission. This detector cancels the Inter-Symbol Interference (ISI) on the basis of the a posteriori error probability estimation. In this context, we show through simulations that MAP-DFE performance improves significantly compared to other well-known detection techniques such as Minimum Mean Square Error (MMSE) and Block DFE (BDFE).
[Studies on the chemical constituents of Aconitum szechenyianum Gay]. (1989)

Five constituents were isolated from Aconitum szechenyianum Gay. The structures of these compounds were identified as beta-sitosterol (I), aconitine (II), 3-acetylaconitine (III), songorine (IV) and a new compound whose structure was elucidated to be szechenyine (V) on the basis of UV, IR, 1HNMR, 13CNMR and Mass spectra.
Determination of drug susceptibility of Mycobacterium tuberculosis through mycolic acid analysis (1997)

In the present work a rapid method to determine the susceptibility of Mycobacterium tuberculosis to isoniazid and streptomycin by determining levels of mycolic acids by high-performance liquid chromatography (HPLC) was developed. Mycobacterial growth kinetics in the presence and absence of antituberculosis drugs was characterized by evaluating the total area corresponding to mycolic acid peaks (TAMA). Results show a linear relationship between the logarithm of CFU per milliliter and TAMA and show that it is possible to detect growth inhibition of M. tuberculosis in the presence of isoniazid or streptomycin by using HPLC in 3 and 4 days, respectively.
Design features of Remington Rand Speed Tally (1954)

Tallying, the recording of the number of occurrences of specific events, although basically a simple repetitive act, has somehow failed to become mechanized in the general trend toward relieving humans of the drudgery of paper work. A tremendous amount of event counting is still recorded in the tally records of modern business establishments in the symbols of the ancients, the four strokes and slash. This system is used especially when the number of different events being tallied is large. It is true that the ticket taker has his thumb-operated counter and the baseball umpire his finger-operated wheels for balls and strikes, but as the number of events grows, the mechanism fails to keep pace. The Electronic Statistical machine has 62 counters and another company makes an analysis machine equipped with 80, but for the problems at hand in the field of merchandising, neither of these is at all adequate. Tens of thousands of counters are required if record of the movement of merchandise bought and sold by even a small mail-order house is to be maintained.
Improved membrane protein topology prediction by domain assignments (2005)

Topology predictions for integral membrane proteins can be substantially improved if parts of the protein can be constrained to a given in/out location relative to the membrane using experimental data or other information. Here, we have identified a set of 367 domains in the SMART database that, when found in soluble proteins, have compartment-specific localization of a kind relevant for membrane protein topology prediction. Using these domains as prediction constraints, we are able to provide high-quality topology models for 11% of the membrane proteins extracted from 38 eukaryotic genomes. Two-thirds of these proteins are single spanning, a group of proteins for which current topology prediction methods perform particularly poorly.
Security Baskets and Index-Linked Securities (1993)

Security baskets and index-linked securities are securities whose values are aggregates of the cash flows or values of other assets. Creation of these "composite" securities improves the welfare of uninformed investors by reducing their trading losses. The introduction of composite securities can also affect real investment decisions. When investors are exposed to nontradeable, heterogeneous risks, different trading equilibria are possible. Markets for multiple composite securities may exist or, when the degree of heterogeneity is high, markets for a single composite security and its component securities may coexist. No results depend on the existence of exogenous "noise" traders. Copyright 1993 by University of Chicago Press.
Reprogramming of B Cells (2010)

Cellular reprogramming is an interplay between the original starting cell's plasticity and the (epi)genetic mechanisms used to drive this cell towards a new fate. Our capacity to reprogram mature cells into progenitors thus greatly depends on the inherent physiological plasticity of the initial cell. B lymphocytes possess a high degree of plasticity revealed both during their normal development and under experimental conditions in the laboratory. In this chapter, we discuss the biology of B cell plasticity in the context of physiology and pathology and we provide a specific practical example of this plasticity in a protocol describing the dedifferentiation of mature B cells into multipotential progenitors that can afterwards be reprogrammed into alternative lineages like T cells or macrophages.
Low Power Error Correction Architecture for Space (1983)

Massively redundant fault-tolerant methods, such as triple modular redundancy require enormously more weight and power than the nonfault-tolerant system and solve only one reliability problem. This paper will show that three reliability problems, random bit flips, error bursts and hard failures can be solved for less than 25 percent more power and 50-100 percent more parts using error detection codes and powered-down spares with repeated execution on detection of error.
Extension, Displacement, and Block Rotation in the Larger Gullfaks Area, Northern North Sea: Determined from Map View Restoration (1996)

Numerical map view restoration of the larger Gullfaks area on the western side of the Viking Graben reveals a Late Jurassic apparent displacement field that is slightly divergent, with displacement vectors trending east-northeast-west-southwest to east-southeast-west-northwest. The predominant extension direction is east-west in the Gullfaks field, changing to east-southeast-west-southwest in the Gullfaks Sor area. We relate the divergent pattern to extensional collapse over low-angle extensional detachments in the eastern part of the area. The detachments also explain the anomalously high extensions in this same area. Total extension in the horizontal plane is estimated to be 19% on average in the larger Gullfaks area, whereas it is 42 and 33% in Gullfaks and Gullfaks So , respectively. Block rotations (about vertical axes) are minor (mostly <5°). Calculated fault-slip directions indicate that major north-south-striking faults are mostly dip-slip, whereas accommodation faults or transfer faults, oriented at high angles to the major faults, tend to be oblique slip. In general, numerical or manual map view restoration is useful before choosing and balancing vertical sections. In most of the Gullfaks area, strain is close enough to plane strain and block rotations are small enough for section balancing to be reliable. East-west sections should be chosen across the main Gullfaks field, and east-southeast-west-northwest sections in the Gullfaks Sor area.
A new bandwidth efficient transmit antenna modulation diversity scheme for linear digital modulation (2002)

A system is proposed and analyzed, which uses several transmit antennas to achieve diversity in a flat fading mobile radio environment. The signals at different antennas carry the same digital information, but have different modulation parameters (modulation diversity). In contrast to other proposals, no bandwidth expansion is required. Modulation diversity for quadrature amplitude modulation (QAM) type modulation is achieved by using different partial response type base pulses. Simulation results confirm the expected gain.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
THE MAJOR DETERMINANTS IN NORMAL AND PATHOLOGICAL GAIT (1953)

Human locomotion is a phenomenon of the most extraordinary complexity in which so great are the multitude of individual motions occurring simultaneously in the three planes of space that analysis is difficult without some unifying principle. The adoption of the concept that fundamentally locomotion is the translation of the center of gravity through space along a pathway requiring the least expenditure of energy supplies the necessary unifying principle which permits of qualitative analysis in terms of the essential determinants of gait. The six major determinants are pelvic rotation, pelvic tilt, knee and hip flexion, knee and ankle interaction, and lateral pelvic displacement. The serial observations of irregularities in these determinants provides insight into individual variation and a dynamic assessment of pathological gait. Pathological gait may be viewed as an attempt to preserve as low a level of energy consumption as possible by exaggerations of the motions at unaffected levels. Compensation is reasonably effective with the loss of one determinant of which that at the knee is the most costly. Loss of two determinants makes effective compensation impossible and the cost of locomotion in terms of energy is increased threefold with an inevitable drain upon the body economy.