gebhart/patrepeval huggingface dataset:
Isolation and characterization of an elastinolytic proteinase from Aspergillus flavus (1990)

An elastinolytic proteinase of Aspergillus flavus has been isolated to homogeneity, and its physical and biochemical properties have been characterized. Two purification protocols were compared; an initial step of ion-exchange chromatography was found to be equivalent to ammonium sulfate precipitation at neutral pH. A combination of gel filtration and adsorption chromatographies on the resultant crude enzyme produced highly purified elastase with yields of 5 to 10%. The enzyme is a 23-kilodalton protein with a pI of 7.6. The enzyme activity is markedly inhibited by numerous metal ions. Aspergillus elastase appears to be a metalloproteinase EC 3.4.24.X), as determined by its sensitivity to 1,10-phenanthroline.
A sensitive turn-on fluorescent probe for intracellular imaging of glutathione using single-layer MnO<sub>2</sub> nanosheet-quenched fluorescent carbon quantum dots (2015)

A sensitive turn-on fluorescent sensor based on single-layer MnO2 nanosheet-quenched fluorescent carbon quantum dots has been developed for rapid and selective sensing of glutathione in aqueous solutions, as well as in living cells.
WHAT'S THAT STUFF? (2003)

RETURN TO ISSUEPREVNewsNEXTWHAT'S THAT STUFF?TEETH WHITENERSFor those seeking a dazzling white smile, polishers and peroxide may do the trickAMANDA YARNELLCite this: Chem. Eng. News 2003, 81, 6, 29Publication Date (Print):February 10, 2003Publication History Published online13 November 2010Published inissue 10 February 2003https://pubs.acs.org/doi/10.1021/cen-v081n006.p029https://doi.org/10.1021/cen-v081n006.p029newsACS PublicationsCopyright © 2003 American Chemical SocietyArticle Views24Altmetric-Citations1LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options SUBJECTS:Calcium phosphate,Hydroxyapatite,Inorganic acids and bases,Layers,Minerals Get e-Alerts
The role of emotion in believable agents (1994)

article Free Access Share on The role of emotion in believable agents Author: Joseph Bates Carnegie Mellon Univ., Pittsburgh, PA Carnegie Mellon Univ., Pittsburgh, PAView Profile Authors Info & Claims Communications of the ACMVolume 37Issue 7July 1994 pp 122–125https://doi.org/10.1145/176789.176803Published:01 July 1994Publication History 698citation3,388DownloadsMetricsTotal Citations698Total Downloads3,388Last 12 Months138Last 6 weeks29 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my Alerts New Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteeReaderPDF
Isolated Word Recognition Using Allophone Unit Hidden Markov Model (1991)

In this paper, we discuss the method of recognizing allophone unit isolated words using hidden Markov model(HMM). Frist we constructed allophone lexicon by extracting allophones from training data and by training allophone HMMs. And then to recognize isolated words using allophone HMMs, it is necessary to construct word dictionary which contains information of allophone sequence and inter-allophone transition probability. Allophone sequences are represented by allophone HMMs. To see the effects of inter-allophone transition probability and to determine optimal probabilities, we performend some experiments. And we showed that small number of traing data and simple train procedure is needed to train word HMMs of allophone sequences and that not less performance than word unit HMM is obtained.
Usefulness of Implantation of Diffractive Multifocal Intraocular Lens in Eyes with Long Axial Lengths (2015)

Purpose. This study retrospectively analyzed the postoperative visual functions of myopic eyes implanted with multifocal intraocular lens (IOL) to evaluate the efficacy of multifocal IOL in highly myopic eyes. Methods. We studied 61 patients (96 eyes) who were implanted with multifocal IOL ZMA00 or ZMB00 (Abbott Medical Optics). The patients were stratified into two groups by axial length: 26 mm or above (AL ≥ 26 group) and below 26 mm (AL < 26 group). Postoperative corrected and uncorrected distance (5 m) and near (30 cm) visual acuity (VA), contrast sensitivity, and depth of focus were compared between two groups. Results. In the AL ≥ 26 group and the AL < 26 group, the mean ± standard deviation uncorrected distance logMAR VA at 12-month postoperative follow-up was -0.04 ± 0.11 and -0.01 ± 0.14, respectively; and the corrected distance VA was -0.17 ± 0.08 and -0.14 ± 0.07, with no significant differences between two groups (p = 0.558 and 0.101; Mann-Whitney U test). For near VA, the corresponding uncorrected VA was 0.06 ± 0.08 and 0.05 ± 0.09; and distance-corrected VA was 0.01 ± 0.06 and 0.01 ± 0.02, with no significant differences between two groups (p = 0.572, and 0.157; Mann-Whitney U test). Conclusion. The present study demonstrates that it is possible to achieve good uncorrected near and distance VA following implantation of multifocal IOL in eyes with long axial lengths.
ChemInform Abstract: SYNTHESIS AND PROPERTIES OF 2‐(2‐α‐FURYLVINYL)‐4,5‐DIARYLIMIDAZOLE (1985)

Abstract Man erhält die im Titel genannten Imidazole (III) durch Kondensation von Furylacrolein (I) mit den α‐Diketonen (II) in siedendem Eisessig in Gegenwart von Ammoniumacetat.
SOLID STATE ELECTROCHEMICAL ALKALI SOURCES FOR COLD ATOM SENSING (2016)

Alkali sources are used as getters, to coat thermionic emission electrodes and to provide alkali atoms for precision quantum sensors such as clocks, magnetometers, accelerometers and gyroscopes. Commercial alkali sources are electrically heated to 400 -700C, driving a chemical reaction which produces the alkali. These sources use high current, high power, operate at high temperatures, turn on and off slowly, and evolve impurities. We report here on solid state electrolytic sources for the production of cesium and rubidium at temperatures of 80C to 170C. The advantages of electrolytic sources over thermally driven sources are reduced current and power consumption, faster turn-on and turn-off, the ability to monitor the quantity of generated alkali by current integration, and reduced temperature of operation. Resistivity and activation energy of the solid ionic conductors was measured vs. temperature. Alkali vapor pressure was detected by optical absorption in a custom vacuum system. Strong alkali signals (comparable to commercial sources) were measured when current was passed through the samples. Reversing the polarity of the applied voltage results in ambient alkali absorption. These Solid State Ambipolar Alkali Sources (SSAAS) show potential as high purity, precision alkali sources for cold atom sensors where size, weight and power must be reduced.
The response of salivary immunoglobulin A to elite surf lifesaving competition (2015)

The present study examined the response of salivary immunoglobulin A (sIgA) to endurance surf lifesaving (SLS) competition. Elite SLS men (n = 10) and women (n =8) volunteered to participate in the present study. Saliva samples of 0.5 mL were collected daily commencing 54 h pre-event to 61 h post-event. Saliva samples were assessed using a portable system. Saliva samples were collected at rest and prior to physical exertion or activity at approximately 0500 hours to determine the pre-and post-competition baseline values, while the post-event sample collection occurred within 30 min of race completion for each athlete, between approximately 1300 – 1600 hours. A significant (p < 0.05) increase in sIgA concentration was observed 61 h post-event (49.21 ± 8.8 μl/mL) in males compared to all other time-point samples. The results of the present study indicate that there is a non-significant increase in sIgA concentration for both genders immediately following an endurance SLS event, lasting approximately 90 min. The mechanism responsible for the non-significant increases in sIgA concentrations observed post-event in both genders and significant increases in sIgA concentrations observed 61 h post event in males remains unclear and may reflect an immune-compensatory effect to protect the athlete from the acquisition of infection. Surf lifesaving athletes and coaches should monitor sIgA concentrations throughout major competition periods to observe fluctuations in mucosal immunity, which may reflect a predisposition to infection, and tailor exercise and recovery prescription accordingly to minimise the risk of infection and subsequent declines in performance.
Switching ACS from Side 1 to Side 2 electronics (2005)

Based on the history of STIS, an electronics failure on the ACS Main Electronic Board, side 1 (MEB1) currently being used could possibly occur at some point. This note describes steps to be taken to switch over to MEB2, the redundant side, including detector startup procedures and recalibration requirements.
Essential role of B-Raf in oligodendrocyte maturation and myelination during postnatal central nervous system development (2008)

Mutations in the extracellular signal-regulated kinase (ERK) pathway, particularly in the mitogen-activated protein kinase/ERK kinase (MEK) activator B-Raf, are associated with human tumorigenesis and genetic disorders. Hence, B-Raf is a prime target for molecule-based therapies, and understanding its essential biological functions is crucial for their success. B-Raf is expressed preferentially in cells of neuronal origin. Here, we show that in mice, conditional ablation of B-Raf in neuronal precursors leads to severe dysmyelination, defective oligodendrocyte differentiation, and reduced ERK activation in brain. Both B-Raf ablation and chemical inhibition of MEK impair oligodendrocyte differentiation in vitro. In glial cell cultures, we find B-Raf in a complex with MEK, Raf-1, and kinase suppressor of Ras. In B-Raf-deficient cells, more Raf-1 is recruited to MEK, yet MEK/ERK phosphorylation is impaired. These data define B-Raf as the rate-limiting MEK/ERK activator in oligodendrocyte differentiation and myelination and have implications for the design and use of Raf inhibitors.
Blood Flow Velocity Estimation from Ultrasound Speckle Tracking Using Chirp Signals (2009)

Ultrasound speckle tracking has been used to estimate the blood flow velocity, because this method can overcome the major limitation of the Doppler method: angle dependence and aliasing. The speckle tracking is based on the brightness of image pixels which always bring difficulty for dark flow areas due to the low reflectivity of blood cells. Therefore, the conventional speckle tracking method is sensitive to signal-to-noise ratio (SNR) of flow and its performance will be significantly deteriorated from existing ultrasound system noise. In this paper, we present a fast sum-absolute-difference (SAD) based speckle tracking method by using chirp signals instead of the conventional broadband signals to increase the flow SNR and investigate the detected errors for flow velocity estimation. Simulation results show that our method can improve the velocity estimation by 12% compared with basic broadband speckle tracking methods.
Diagnosis of late-infantile neuronal ceroid lipofuscinosis: A new sensitive method to assay lysosomal pepstatin-insensitive proteinase activity in human and animal specimens by capillary electrophoresis (2001)

Batten disease, or human late-infantile neuronal ceroid lipofuscinosis (LINCL) is a familiar progressive degenerative disease affecting children, caused by a deficiency of a lysosomal proteinase (tripeptidyl peptidase I, TPP-I) and characterized by the accumulation of autofluorescent storage bodies in the brain and other tissues of the body. Current methodology used to diagnose this disease needs to be improved in order to have less invasive techniques with higher resolution and shorter assay time. In this report, we discuss the potential merits of micellar electrokinetic chromatography as an excellent tool that requires minute samples but offers high resolution and a short running time for monitoring TPP-I activity in human and animal specimens.
The history of the classical vowel articulation model: a reply to Catford and Fischer-Jørgensen (1987)

This paper is devoted to a discussion of Catford's and Fischer-Jørgensen's defence of the classical vowel articulation model (1, 2, 3). Objections to the model are not directed at Bell's personality, but at the theoretical structure of his model: critical functions of the model are contradicted by empirical data and by acoustical theory. Nor are the ojections only relevant for amendments introduced by Jones. That argument is contradicted by the chronology of the debate. # J. C. Catford, 1981, "Observations on the recent history of vowel classification", in R. E. Asher and J. A. Henderson eds., Towards a History of Phonetics, 19-32, Edinburgh University Press, Edinburgh. # E. Fischer-Jørgensen, 1983, "Vowel features and their explanatory power in phonology", in Abstracts of the 10th Int. Congress of Phonetic Sciences, 259-265, Foris Publications, Dordrecht. # E. Fischer-Jørgensen, 1985, "Some basic vowel features, their articulatory correlates, and their explanatory power in phonology", in V. Fromkin ed., Phonetic Linguistics, 79-99, Academic Press, Orlando).
Comparison of active damping systems for the doubly-fed induction generator (2008)

The doubly-fed induction generator (DFIG) is characterized by two poles near the imaginary axis on the complex plane. This leads to poorly damping oscillations. To damp these oscillations several methods can be used. This paper compares, using a detailed simulation program, four active damping systems that inject on the rotor a damping current in order to damp stator-flux oscillations. The purpose is to evaluate which damping method provides the best damping using less additional rotor current. For damping transients originated on the stator, e.g. voltage dips, all the methods analyzed need high values of rotor damping current. The two axis damping method that uses variations of state variable is the method that uses lower values of rotor current for the same damping action.
Simultaneous measurement of birefringence magnitude and direction using Wollaston prism (2012)

Simultaneous measurement of the birefringence magnitude and direction using Wollaston prism is presented. The sinusoidally modulated laser beam passes through a circular polarizer, the birefringence sample and is split by a Wollaston prism. The measuring beam is then detected by a bi-cell detector and two alternating current signals are detected. Then the Wollaston prism is rotated by 45°, and another two alternating current signals are obtained. By processing the four signals, the birefringence magnitude and direction is resolved simultaneously. In experiments, a wedge waveplate was laterally moved and measured at different birefringence magnitude. The measured birefringence magnitude linearly increased as the wedge waveplate was laterally moved. The maximum standard deviation of the birefringence magnitude and direction is 0.11° and 0.05°The usefulness of this method is verified.
Shopping Context and the Impulsive and Compulsive Buyer (2013)

Abstract- Impulsive and compulsive buying are behaviors with unique antecedents and consequences. Each has been studied at length but not in the duel context of offline and online retail environments. This current research examines the interaction of shopping context (online or offline) in relation to impulsive and compulsive buying behaviors. We find evidence that compulsive buying tendency is positively associated with online shopping, while impulse buying tendency is positively associated with offline shopping. The implications of this research suggest that purchasing as a result of compulsive and impulsive buying tendencies vary as a result of the shopping context which includes physical proximity to product and store atmospherics. This study reports the behavior of 353 young adults who provide a survey and shopping diary data over a two-week period during the U.S. holiday of Thanksgiving.
The role of the bacitracin ABC transporter in bacitracin resistance and collateral detergent sensitivity (2000)

The bacitracin resistance of Bacillus licheniformis, a producer of bacitracin, is mediated by the ABC transporter Bcr. Bacillus subtilis cells carrying bcr genes on high-copy number plasmids developed collateral detergent sensitivity, as did human cells with overexpressed multidrug resistance P-glycoprotein. Resistance against bacitracin and sensitivity of resistant cells to detergents were shown to be inseparable phenomena associated with the membrane part of Bcr transporter, namely protein BcrC. A fused protein, consisting of ATP-binding protein BcrA and membrane component BcrC was constructed. It resembled a half molecule of P-glycoprotein and was capable of providing a significant degree of antibiotic resistance and detergent sensitivity.
Narodowy plan rozwoju jako przesłanka planowania finansowego w zakresie ochrony środowiska (2005)

"W sferze prowadzenia publicznej działalności finansowej istotnym przejawem\npraktycznej realizacji zasady racjonalnego gospodarowania jest odpowiednie\nuporządkowanie celów polityki finansowej państwa1. Wraz z przystąpieniem\nPolski do Unii Europejskiej podstawowym instrumentem określania\ncelów polityki finansowej państwa stało się planowanie. Proces harmonizacji\nprawa polskiego z prawem Unii Europejskiej doprowadził do tworzenia\nlicznych planów i strategii dalszego rozwoju właściwie we wszystkich dziedzinach\nzwiązanych z funkcjonowaniem państwa. Polityka planowania pozostaje\nw bezpośrednim związku z możliwością pozyskiwania przez Polskę\nśrodków funduszy strukturalnych."(...)
Oxyzimtalkohole und ihre Dehydrierungs‐polymerisate (1952)

Abstract Für die Bereitung des Coniferyl‐ und Sinapinalkohols werden verbesserte Vorschriften gegeben Die Dehydrierungs‐polymerisation des Coniferylalkohols kann bei einer kristallinen dimeren Stufe dem Dehydro‐diconiferylalkohol, festgehalten werden. Seine Konstitution wurde bestimmt. Durch weitere Dehydrierung verwandelt er sich in ligninartige Produkte. Außer der Pilzredoxase kann für die Bereitung des Dehydro‐diconiferylalkohols auch das Redoxasesystem des in Verholzung begriffenen Gewebes verwendet werden. Es ist daher nicht zu bezweifeln, daß diese Substanz ein wesentliches Bauelement des natürlichen Lignins ist.
Clinical aspects of atopic dermatitis (2000)

Journal Article Clinical aspects of atopic dermatitis Get access K. Thestrup‐Pedersen K. Thestrup‐Pedersen Department of Dermatology, Marselisborg Hospital, University of Aarhus, Denmark K. Thestrup‐Pedersen, Department of Dermatology, Marselisborg Hospital, University of Aarhus, DK‐8000 Aarhus C., Denmark. Tel.: +45 89491852. Fax: +45 89491850.E‐mail: ktp56@hotmail.com Search for other works by this author on: Oxford Academic Google Scholar Clinical and Experimental Dermatology, Volume 25, Issue 7, 1 September 2000, Pages 535–543, https://doi.org/10.1046/j.1365-2230.2000.00696.x Published: 01 September 2000
New drug therapies in peripheral T-cell lymphoma (2011)

Peripheral T-cell lymphomas (PTCLs) are a heterogeneous collection of lymphomas that are associated with very poor prognosis. Conventional therapies, historically based on protocols for aggressive B-cell lymphomas, deliver less than adequate outcomes; the majority of patients experience early relapse after front-line treatment and current 5-year overall survival is only 10-30%. Clearly, new approaches are needed. In recent years there has been a plethora of novel agents showing activity in PTCL, often in patients with advanced relapsed or refractory disease. These agents include antifolate drugs (pralatrexate), histone deacetylase inhibitors (vorinostat, romidepsin, panobinostat and belinostat), nucleoside analogues (gemcitabine, forodesine and clofarabine), monoclonal antibodies (anti-CD52, anti-CD4 and anti-CD2), fusion toxins (denileukin diftitox), immunomodulatory agents (lenalidomide) and proteasome inhibitors (bortezomib). This is an exciting time in the treatment of PTCL, as our ever improving understanding of the distinguishing features, pathogenesis, molecular biology and progression of PTCL, and the knowledge of the mechanism and efficacy of novel therapies, may see a real improvement in outcomes for patients. The purpose of this article is to focus on these novel therapies and the results of recent clinical trials in PTCL.
Oxygen Barrier Coatings Based on Supramolecular Assembly of Melamine (2000)

Gas permeability is one of the key performance characteristics of polymeric films. Here we explore a novel approach for modifying the oxygen transmission rate of polymers by vapor deposition of melamine. We will show that melamine, upon physical vapor deposition, forms a transparent uniform layer on polymeric films such as biaxially oriented polypropylene. X-ray diffraction, in combination with molecular modeling, has indicated that the melamine coating is crystalline and macroscopically oriented with the preferred direction of the melamine molecules parallel to the (polymeric) substrate. The vapor-deposited melamine molecules undergo a large number of cooperative hydrogen bond interactions leading to a coherent layer of an infinite supramolecular network. The melamine coating acts as a surprisingly effective barrier against gases, decreasing drastically, for example, the oxygen transmission rate through coated polymer films by 2 orders of magnitude. The effect is attributed to the crystalline nature of the deposited melamine layer, strengthened by the high level of hydrogen bonding. This is the first example of application of supramolecular chemistry for the production of health and environment friendly transparent barrier coatings against oxygen. The vacuum-coating process with melamine and related compounds is expected to bring a major breakthrough in the field of transparent polymeric barrier films for applications, for example, in food and pharmaceutical packaging.