gebhart/patrepeval huggingface dataset:
<i>ß</i>-Glucuronidase Activity in the Urine of Patients with Bladder Cancer and Other Conditions (1961)

No AccessJournal of Urology1 Jul 1961ß-Glucuronidase Activity in the Urine of Patients with Bladder Cancer and Other Conditions * Meyer M. Melicow, Aurelio C. Uson, and Rita Lipton Meyer M. MelicowMeyer M. Melicow , Aurelio C. UsonAurelio C. Uson , and Rita LiptonRita Lipton View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)65114-0AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail © 1961 by The American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetailsCited byKallet H and Lapco L (2018) Urine Beta Glucuronidase Activity in Urinary Tract DiseaseJournal of Urology, VOL. 97, NO. 2, (352-356), Online publication date: 1-Feb-1967. Volume 86Issue 1July 1961Page: 89-94 Advertisement Copyright & Permissions© 1961 by The American Urological Association Education and Research, Inc.MetricsAuthor Information Meyer M. Melicow More articles by this author Aurelio C. Uson More articles by this author Rita Lipton More articles by this author Expand All Advertisement PDF downloadLoading ...
Q-switched ruby laser damage of the rabbit eye lens. (1977)

<p>The cold-bonding pelletizing technique is applied in this study as an integrated method to recycle municipal solid waste incineration (MSWI) bottom ash fines (BAF, 0–2 mm) and several other industrial powder wastes. Artificial lightweight aggregates are produced successfully based on the combination of these solid wastes, and the properties of these artificial aggregates are investigated and then compared with others’ results reported in literature. Additionally, methods for improving the aggregate properties are suggested, and the corresponding experimental results show that increasing the BAF amount, higher binder content and addition of polypropylene fibres can improve the pellet properties (bulk density, crushing resistance, etc.). The mechanisms regarding to the improvement of the pellet properties are discussed. Furthermore, the leaching behaviours of contaminants from the produced aggregates are investigated and compared with Dutch environmental legislation. The application of these produced artificial lightweight aggregates are proposed according to their properties.</p>
Nuclear spin relaxation in ligands outside of the first coordination sphere in a gadolinium (III) complex:  Effects of intermolecular forces (2002)

This article describes paramagnetic relaxation enhancement (PRE) in systems with high electron spin, S, where there is molecular interaction between a paramagnetic ion and a ligand outside of the first coordination sphere. The new feature of our treatment is an improved handling of the electron-spin relaxation, making use of the Redfield theory. Following a common approach, a well-defined second coordination sphere is assumed, and the PRE contribution from these more distant and shorter-lived ligands is treated in a way similar to that used for the first coordination sphere. This model is called “ordered second sphere,” OSS. In addition, we develop here a formalism similar to that of Hwang and Freed [J. Chem. Phys. 63, 4017 (1975)], but accounting for the electron-spin relaxation effects. We denote this formalism “diffuse second sphere,” DSS. The description of the dynamics of the intermolecular dipole–dipole interaction is based on the Smoluchowski equation, with a potential of mean force related to the radial distribution function. We have used a finite-difference method to calculate numerically a correlation function for translational motion, taking into account the intermolecular forces leading to an arbitrary radial distribution of the ligand protons. The OSS and DSS models, including the Redfield description of the electron-spin relaxation, were used to interpret the PRE in an aqueous solution of a slowly rotating gadolinium (III) complex (S=7/2) bound to a protein.
Acetylation of Nucleosomal Histones <i>in vitro</i> (1980)

A new histone-specific acetyltransferase, which is closely associated with nucleosomes prepared from lymphocyte nuclei by treatment with micrococcal nuclease, is described. The acetylating enzyme transfers [3H]acetyl groups from [3H]acetyl-coenzyme A to the endogenous histones H2A, H2B, H3 and H4 in nucleosomes as well as to free histones added to the reaction mixture. Histone H1 is not acetylated by this enzyme. The acetyltransferase was partially purified by DEAE-Sephadex and DNA-cellulose chromatography. The nucleosome-associated enzyme binds to DNA cellulose at low salt concentrations (DNA-binding acetyltransferase), while the previously described histone-specific acetyltransferases have no affinity to DNA under these conditions. This high affinity for DNA may explain the association of DNA-binding acetyltransferase with nucleosomes.
Burn wound coverage and burn wound closure. (2000)

Early excision and grafting changed dramatically topical wound treatment, but are restricted by difficulty in diagnosing burn depth, by limited donor sites and by technical skills to excise special areas (perineum, face). In addition to the extent of burn and the age of the patient the depth is determinant of mortality, morbidity and of patient's quality of life. It results from the time-temperature relation and is further influenced by local and systemic causes of conversion: dehydration, edema, infection and shock hypoxia, metabolic derangements, peripheral vessels diseases may contribute do deepening of burn wound. Superficial burn on day one appears deep dermal by day three, where spontaneous epithelization lasts much longer than 21 days and results in hypertrophic scarring. To prevent this sequelae deep dermal burn may be treated like full-thickness injury with excision and autografting. Another way is removal of dead layers of corium and using biological or synthetic cover. We have found a more effective way to reach wound closure (not only cover) in the method of "upside-down" application of recombined human/pig skin (RHPS), composed of allogeneic human keratinocytes cultured on cell-free pig dermis. The allogeneic epidermal cells temporarily "take", "close" the excised wound and simultaneously encourage epithelization from adnexa remnants in the wound bed. Thus definitive closure is achieved.
Reaction Diffusion Enhanced Termination in Polymerizations of Multifunctional Monomers (1993)

A model was developed to predict the reaction behavior of multifunctional monomers during photopolymerization. The model incorporates transition regions from reaction to diffusion controlled propagation and termination, a reaction diffusion termination mechanism and volume relaxation, and is able to predict reaction rates, radical concentrations, and kinetic constants for termination and propagation. For reactions leading to highly crosslinked polymers, the reaction diffusion termination mechanism was significant even at low conversions and dominated as the polymerization proceeded. Reaction diffusion was evidenced by plateau regions in the termination kinetic constant, which were found to be most dependent on two model parameters, monomer size and a mass transfer ratio.
Scattering and recoiling analysis of oxygen adsorption site on the Ir{110}-<i>c</i>(2×2)-O surface (1991)

The oxygen adsorption site on the Ir{110}-c(2×2)-O surface has been studied by time-of-flight scattering and recoiling spectrometry (TOF-SARS) using 4 keV Ne+ for backscattering and Ar+ for recoiling. The oxygen site was analyzed from scans of (i) backscattering intensity versus incident angle, (ii) oxygen recoil intensity versus incident and azimuthal angle, and (iii) oxygen recoil energy versus azimuthal angle. Calibrated shadow cones and trajectory simulations were used to obtain the site coordinates. This TOF-SARS data is contrasted with that of Ni{110}-p(2×1)-O, in which it is well established that the adsorption site is in the long-bridge position along the 〈001〉 rows. Adsorption of oxygen in the short-bridge sites above the 〈11̄0〉 Ir rows is the only model consistent with all of the experimental data and simulations. The O–Ir bond length is estimated to be ≊1.8 Å.
On the Advantages of Using Multiuser Receivers in Wireless Ad-Hoc Networks (2009)

We consider the problem of cross-layer utility maximization subject to stability constraints for a multicommodity wireless network where all links are sharing a single channel. We assume a time slotted network and only one node is allowed to transmit at any given slot. The optimal cross-layer network control policy can be decomposed into three subproblems: (1) flow control at the transport and network layers, (2) routing and scheduling at the network layer, and (3) resource allocation (RA) at the medium access control and physical layers. Every time slot, a network controller decides the transmitter node, amount of each commodity data admitted to the network layer, schedules different commodities over networks' links and controls the power and rate allocated to every link. In this paper we provide solutions for the RA subproblem for two scenarios: (1) when the nodes are equipped with standard single user receivers, and (2) when the nodes are equipped with multiuser receivers performing successive interference cancelation. In addition we propose decentralized algorithms to obtain the solution of RA subproblem for each scenario. The numerical results show that as the signal-to-noise ratio increases, using multiuser receivers can provide significant gains at the network layer in terms of end-to-end rates and network congestion as compared to that of single user receivers.
Reliability evaluation of MOCVD grown AlInAs-GaInAs-InP HEMTs (2003)

We report on the reliability evaluation of MOCVD grown single and double delta doped AlInAs-GaInAs-InP HEMTs. It is found that HEMTs with thin InP top surface layer provide high threshold voltage uniformity, and less thermal stress degradation compared to conventional AlInAs-GaInAs-InP HEMTs. Furthermore, hot electron stress measurements have been conducted on passivated and unpassivated HEMTs. A temporary negative shift in the threshold voltage for unpassivated HEMTs and permanent negative shift in the threshold voltage for passivated HEMTs has been obtained. The shift in the threshold voltage is related to the build-up of holes inside the Schottky layer (temporary) and/or at the semiconductor-passivation layer interface (permanent).
Membrane proteins of the myocytes in cardiac overload. (1990)

1. Hypertrophy of the cardiac myocytes resulting from a mechanical overload may be responsible for major membraneous modifications, either at the sarcolemmal or at the sarcoplasmic level. In this study several sarcolemmal markers such as beta-adrenoceptors, muscarinic receptors or (Na+, K+)-ATPase were investigated in an experimental model of cardiac hypertrophy, the chronic aortic stenosis in adult rats. 2. Left ventricular beta-adrenoceptor density (expressed in fmol mg-1 protein) was decreased in the aortic stenosis group by about 30%; however, when expressed in number of receptors per cardiac cell beta-adrenoceptor number in the hypertrophied myocytes was unchanged. 3. Similarly, the number of muscarinic receptors in the hypertrophied cells, expressed as number of receptors per cardiac cell, was unchanged. 4. The number of (Na+, K+)-ATPase molecules with high affinity for ouabain was markedly increased in the hypertrophied myocytes, while those with low affinity for ouabain were not. 5. These results indicate the necessity in chronic hypertrophy to calculate receptors not only in density (fmol mg-1 protein) but also in number per cardiac cell. The unchanged number of beta-adrenergic and muscarinic receptors present on the hypertrophied myocytes suggests a non-regulation for the genes coding for these receptors.
Pharmacokinetics and safety profile of single-dose administration of an estrogen receptor β-selective phytoestrogenic (phytoSERM) formulation in perimenopausal and postmenopausal women (2017)

A single-dose oral administration of the phytoSERM formulation was well-tolerated and did not elicit any adverse events. It was rapidly absorbed, reached high plasma concentrations, and showed a linear dose-concentration response in its pharmacokinetics. These findings are consistent with previously reported parameters for each parent compound (Clinicaltrials.gov NCT01723917).
Alkyl Monolayers on Silica Surfaces Prepared from Neat, Heated 3-Glycidoxypropyldimethylethoxysilane Analyzed by XPS (2001)

Silane monolayers on silica, prepared from mono-, di-, and trichlorosilanes, are widely used in industry for surface functionalization and modification. However, unlike di- and trichlorosilanes, monochlorosilanes are particularly easy to work with because they can dimerize, but not polymerize, upon reaction with water. Typically, an organic solvent is used when depositing a silane monolayer. Here we show XPS spectra of monolayers of 3-glycidoxypropyldimethylethoxysilane (CAS# 17963-04-1) on silicon oxide (silicon wafer) prepared using a rapid, solvent-free approach. Reaction conditions are 100 °C for 10 min using the neat (pure) compound, and no inert atmosphere or special treatment of the compound is required.
Efficiency of Neonatal Screening for Congenital Adrenal Hyperplasia Due to 21-Hydroxylase Deficiency in Children Born in Mainland France Between 1996 and 2003 (2012)

In this large population-based study, the efficiency of routine 21-OHD screening was moderate in neonates born at term and very low in preterm neonates. We recommend the discontinuation of screening, as currently performed in France, in preterm neonates.
Casein hydrolysates as a source of antimicrobial, antioxidant and antihypertensive peptides (2007)

The aim of this work was to investigate the presence of antioxidant and ACE-inhibitory activity in ovine αs2-casein and bovine κ-casein hydrolysates with antibacterial activity. Several peptides which had been previously identified in these hydrolysates were selected in order to fulfil certain structural requirements and they were chemically synthesised to evaluate their antioxidant and ACE-inhibitory activity. Hydrolysates of ovine αs2-casein and bovine κ-casein with pepsin strongly inhibited ACE activity, with IC50 values of 41.8 and 9.97 μmol·L−1, respectively. The κ-casein hydrolysate also exhibited a significant oxygen radical absorbance capacity, seven times higher than that of Trolox. From the chemically synthesised peptides, two of them, LKKISQ and PYVRYL, both from ovine αs2-casein, exerted potent ACE-inhibitory activity in the range of the most potent food-derived antihypertensive peptides described to date (IC50 values of 2.6 and 2.4 μmol·L−1, respectively). The latter sequence, corresponding to the C-terminal hexapeptide of the ovine αs2casein molecule, also had antioxidant activity. The activity found is discussed in relation to the peptide sequences.
STMBench7 (2007)

Software transactional memory (STM) is a promising technique for controlling concurrency in modern multi-processor architectures. STM aims to be more scalable than explicit coarse-grained locking and easier to use than fine-grained locking. However, STM implementations have yet to demonstrate that their runtime overheads are acceptable. To date, empiric evaluations of these implementations have suffered from the lack of realistic benchmarks. Measuring performance of an STM in an overly simplified setting can be at best uninformative and at worst misleading as it may steer researchers to try to optimize irrelevant aspects of their implementations. This paper presents STMBench7: a candidate benchmark for evaluating STM implementations. The underlying data structure consists of a set of graphs and indexes intended to be suggestive of many complex applications, e.g., CAD/CAM. A collection of operations is supported to model a wide range of workloads and concurrency patterns. Companion locking strategies serve as a baseline for STM performance comparisons. STMBench7 strives for simplicity. Users may choose a workload, number of threads, benchmark length, as well as the possibility of structure modification and the nature of traversals of shared data structures. We illustrate the use of STMBench7 with an evaluation of a well-known software transactional memory implementation.
Structural characterization of the fructose 1,6-bisphosphatase (II) from<i>M. tuberculosis</i> (2011)

The Haemophilus influenzae HMW1 adhesin is an N-linked glycoprotein that mediates adherence to respiratory epithelium, an essential early step in the pathogenesis of H. influenzae disease. HMW1 is glycosylated by HMW1C, a novel glycosyltransferase in the GT41 family that creates N-glycosidic linkages with glucose and galactose at asparagine residues and di-glucose linkages at sites of glucose modification. Here we report the crystal structure of Actinobacillus pleuropneumoniae HMW1C (ApHMW1C), a functional homolog of HMW1C. The structure of ApHMW1C contains an N-terminal all domain (AAD) fold and a C-terminal GT-B fold with two Rossmannlike domains and lacks the tetratricopeptide repeat fold characteristic of the GT41 family. The GT-B fold harbors the binding site for UDPhexose, and the interface of the AAD fold and the GT-B fold forms a unique groove with potential to accommodate the acceptor protein.
The prevalence of intraventricular dyssynchrony, detected by tissue synchronization imaging, in hemodialysis, peritoneal dialysis and chronic kidney disease stages 3 and 4. (2009)

The prevalence of intraventricular dyssynchrony, detected by tissue synchronization imaging, in hemodialysis, peritoneal dialysis and chronic kidney disease stages 3 and 4.
SINR order statistics in OFDMA systems (2012)

In orthogonal frequency division multiple access downlink, the signal-to-interference-noise ratio (SINR) of every subband at each user is estimated with the aid of pilots and the channel quality (some function of SINR's) is fed back to the base station (BS). This information is utilized by the BS for downlink scheduling. However, the SINR of the bands at each user are correlated due to the common interfering BSs. In this paper, we obtain the order statistics of band SINR's by considering the the co-channel interference and taking the correlations of interference across the bands into consideration. The order statistics are then used to analyse a best-m band feedback scheme, in which every users reports the index of their best-m bands to the BS. The BS utilizes this information and does greedy allocation of the bands to the users. We observe that utilizing the partial ordering of SINR's for channel allocation provides substantial gains over random allocation of bands to the users even in the presence of interference.
Statistical Basis for Predicting Technological Progress (2013)

Forecasting technological progress is of great interest to engineers, policy makers, and private investors. Several models have been proposed for predicting technological improvement, but how well do these models perform? An early hypothesis made by Theodore Wright in 1936 is that cost decreases as a power law of cumulative production. An alternative hypothesis is Moore's law, which can be generalized to say that technologies improve exponentially with time. Other alternatives were proposed by Goddard, Sinclair et al., and Nordhaus. These hypotheses have not previously been rigorously tested. Using a new database on the cost and production of 62 different technologies, which is the most expansive of its kind, we test the ability of six different postulated laws to predict future costs. Our approach involves hindcasting and developing a statistical model to rank the performance of the postulated laws. Wright's law produces the best forecasts, but Moore's law is not far behind. We discover a previously unobserved regularity that production tends to increase exponentially. A combination of an exponential decrease in cost and an exponential increase in production would make Moore's law and Wright's law indistinguishable, as originally pointed out by Sahal. We show for the first time that these regularities are observed in data to such a degree that the performance of these two laws is nearly the same. Our results show that technological progress is forecastable, with the square root of the logarithmic error growing linearly with the forecasting horizon at a typical rate of 2.5% per year. These results have implications for theories of technological change, and assessments of candidate technologies and policies for climate change mitigation.
Digital Image Analysis of Endoscopic Images of Diminutive Polyps (2008)

Purpose: Endoscopic digital images contain rich information on texture and color. There is increasing interest in differentiating tissue pathology based on the patterns of color and texture features of endoscopic images extracted by digital image analysis (DIA). Objective: In this study, we applied techniques of DIA to endoscopic images of diminutive polyps in order to identify the color and texture features of endoscopic images that may differentiate adenomatous polyps from hyperplastic polyps. Methods: Methods: Our endoscopic image database was searched to retrieve and store digital images of diminutive polyps with diagnosis confirmed by histopathology. Texture analysis was performed on multiple regions of interest (ROIs) digitally selected in these images using the MatLab image processing toolbox; the following texture parameters were extracted: histogram (first order statistics) run-length and co-occurrence matrix (measuring features of runs of pixels and distribution of pairs of pixels), gradient analysis (spatial distribution of pixels), auto-regressive analysis (measurement of local interaction amongst pixels of different grey level values) and also wavelet analysis (which measures parameters of spatial frequency). Principal component analysis (PCA) was used for data reduction, and an artificial neural network (NN) based predictive model was built, trained and validated using the extracted texture features for classification of adenomatous polyps from hyperplastic polyps. Results: Results: A total of 110 and 109 ROIs were selected from endoscopic images of 30 and 28 patients with diminutive adenomatous and hyperplastic polyps, respectively. The sensitivity and specificity of the multilayered perceptron neural network classification model were both 82% with an area under the receiver operating characteristic (ROC) curve of 0.87. Three types of features of pixel distribution had high discriminatory power: Kurtosis (measure of the steepness of the pixel distribution), angular second momentum and horizontal and vertical grey level non-uniformity (parameters estimating the second order joint conditional probability density functions of spatial distribution of two neighboring pixels) Conclusion: Conclusion: Results of this exploratory study suggest that the technique DIA may be a clinically useful adjunct for non-invasive automated diagnosis of diminutive colon polyps, particularly if available as a real-time application.
Effect of Cobalt Content on Fatigue Lifetimes and Short Fatigue Crack Growth Behavior of Tungsten‐Cobalt Cemented Carbides (2014)

This chapter contains sections titled: Introduction Material and Experimental Procedures Experimental Procedures Results Discussion Conclusions
Microcirculatory Dysfunction in the Brain Precedes Changes in Evoked Potentials in Endotoxin-Induced Sepsis Syndrome in Rats (2006)

For the first time we demonstrate microcirculatory dysfunction in the activation flow coupling of the brain. Inappropriate blood supply of neurons might explain the disturbance of neuronal function.