gebhart/patrepeval huggingface dataset:
Soluble intercellular adhesion molecule-1 (sICAM-1) in Graves' disease. (1994)

The aim of this study was to determine the level of sICAM-1 in sera of hyperthyroid and euthyroid patients with Graves' disease and find correlation between thyroid function, anti-TSH receptor as well as anti-thyroid antibodies. Comparative determination of sICAM-1, TSH and thyroid hormones, anti-TSH receptor- as well as anti-thyroglobin-, anti-thyroid peroxidase antibodies was made in sera of Graves' patients. Thirty patients with untreated hyperthyroid Graves' disease (12 had infiltrative ophthalmopathy) were studied before and after methimazole treatment. sICAM-1 was measured by ELISA using monoclonal antibodies to human ICAM-1. The sICAM-1 was significantly elevated in hyperthyroid Graves' patients (738.9 +/- 151 ng/ml) compared to controls (212 +/- 42 ng/ml) (p < 0.0001). Both in hyperthyroid and euthyroid Graves' groups with infiltrative ophthalmopathy the sICAM-1 proved to be higher than those without ophthalmopathy. Correlations were observed between sICAM-1 and serum thyroxine, triiodothyronine and anti-TSH receptor antibodies (r = 0.91, 0.83 and 0.61, respectively). There was, however, no association of serum ICAM-1 levels with anti-thyroid peroxidase or anti-thyroglobulin antibodies. It was concluded that elevation of sICAM-1 can be the consequence of hyperthyroidism and the autoimmune processes mediated by anti-TSH receptor antibodies as well as cytokines. The elevated level of sICAM-1 might be important both in regulation of autoimmune mechanism and "homing" phenomenon of lymphocytes in Graves' disease.
Activation of the cAMP–protein kinase A pathway facilitates Na<sup>+</sup> translocation by the Na<sup>+</sup>–K<sup>+</sup> pump in guinea‐pig ventricular myocytes (2000)

1. The effects of the adenylyl cyclase activator forskolin on steady-state and transient currents generated by the Na+-K+ pump were studied in guinea-pig ventricular myocytes by means of whole-cell voltage clamp at 30 C. 2. In external solution containing 144 mM Na+ (Na+o) and 10 mM K+ (K+o), steady-state Na+-K+ pump current (Ip) activated by 5 mM pipette Na+ (Na+pip) at -20 mV was reversibly augmented by forskolin (4 microM) to 133 +/- 4 % of the control current (n = 15). The forskolin analogue 1, 9-dideoxyforskolin (10 microM), which does not activate adenylyl cyclases, did not increase Ip (n = 2). Application of the protein kinase A (PKA) inhibitor H-89 (10 microM) in the continued presence of forskolin reversed the forskolin-induced elevation of Ip (n = 3). 3. The forskolin effect on Ip persisted in the presence of 50 mM Na+pip which ensured that the internal Na+-binding sites of the Na+-K+ pump were nearly saturated. Under these conditions, the drug increased Ip to 142 +/- 3 % of the control Ip when the pipette free Ca2+ concentration ([Ca2+]pip) was 0.013 nM (n = 5) and to 138 +/- 4 % of the control Ip when free [Ca2+]pip was 15 nM (n = 9). 4. In Na+-free external solution, Ip activated by 50 mM Na+pip and 1.5 mM K+o was likewise increased by forskolin but to a lesser extent than in Na+-containing medium (116 +/- 3 % of control, n = 10). 5. In order to investigate exclusively partial reactions in the Na+ limb of the pump cycle, transient pump currents under conditions of electroneutral Na+-Na+ exchange were studied. Transient pump currents elicited by voltage jumps displayed an initial peak and then decayed monoexponentially. Moved charge (Q) and the rate constant of current decay varied with membrane potential (V). The Q-V relationship followed a Boltzmann distribution characterized by the midpoint voltage (V0.5) and the maximum amount of movable charge (DeltaQmax). Forskolin (2-10 microM) shifted V0.5 to more negative values while DeltaQmax was not affected (n = 11). The effects of forskolin on transient pump currents were mimicked by 8-bromo-cAMP (500 microM; n = 2) and abolished by a peptide inhibitor of PKA (PKI, 10 microM; n = 5). 6. We conclude that activation of the cAMP-PKA pathway in guinea-pig ventricular myocytes increases Na+-K+ pump current at least in part by modulating partial reactions in the Na+ limb of the pump cycle. Under physiological conditions, the observed stimulation of the cardiac Na+-K+ pump may serve to shorten the action potential duration and to counteract the increased passive sarcolemmal Na+ and K+ fluxes during sympathetic stimulation of the heart.
A new ZVS semiresonant high power factor rectifier with reduced conduction losses (1999)

This paper presents a novel single-phase unity power factor rectifier, which features critical conduction mode and zero-voltage switching. The reduced conduction losses are achieved by the employment of a single converter, instead of the typical configuration composed of a front-end rectifier followed by a boost converter. Theoretical analysis, a design example, and experimental results of a 300 W converter with 127 V/sub rms/ input voltage and 400 V/sub DC/ output voltage are presented.
Glutathione peroxidase codon 198 polymorphism variant increases lung cancer risk. (2000)

Human cellular glutathione peroxidase 1 (hGPX1) is a selenium-dependent enzyme that participates in the detoxification of hydrogen peroxide and a wide range of organic peroxides. We conducted a case-control study nested within the alpha-Tocopherol, beta-Carotene Cancer Prevention Study cohort to evaluate the association between the proline to leucine polymorphism at codon 198 of hGPX1 and lung cancer risk. Cases (n = 315) were matched to controls on age (+/-5 years), intervention group, and study clinic using incidence density sampling in a 1:1 ratio. The prevalence of the hGPX1 Pro198Leu variant allele was 58% for controls and 71% for cases (P < 0.001). Using conditional logistic regression, we found a significant association between hGPX1 genotype and lung cancer risk. The odds ratio for heterozygotes was 1.8 (95% confidence interval, 1.2-2.8) and 2.3 (95% confidence interval, 1.3-3.8) for homozygous variants compared to wild-type individuals. Due to its high prevalence, the hGPX1 variant may contribute significantly to lung cancer risk among Caucasians but not among ethnic Chinese who do not exhibit this polymorphism.
The Role of the Spanish Central State in the Negotiation of Cohesion Policy (2000)

The development of EU cohesion policy has been a priority for Spain throughout its membership of the Community. Chapter 4 analyses the key role the Spanish government played in setting the agenda, and negotiating the optimal level of funding. A substantial body of literature on cohesion policy focuses on the increasing role played by regional governments, arguing that central government is less in control of the policy-making process in view of enhanced subnational input. The multi-level governance approach has frequently been used for the analysis of regional policy, where theorists seek to illustrate the potential threat to the monopoly of central government over European policy-making represented by increased regional mobilization, as illustrated in Chapter 1. Chapter 4 tests this assumption by focusing on the resilience of state political and bureaucratic elites, particularly during the policy initiation and decision-making phases, which has led to the 'retention of almost exclusive powers of negotiation by the states in the phase of policy formulation with the Commission' (Nanetti, 1996, p. 87). This chapter considers the development of cohesion policy, the role played by the Spanish government in negotiations, and the interaction between the EC and domestic arenas, with a view to gaining a better understanding of the role played by the central state at key stages in the policy process. Chapter 5 will then consider the role of actors other than the central state in the area of cohesion policy.KeywordsMember StateGross Domestic ProductCentral GovernmentAutonomous CommunityOpposition PartiThese keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
Real-Time Human Motion Behavior Detection via CNN Using mmWave Radar (2018)

A real-time behavior detection system using millimeter wave radar is presented in this article. Radar is used to sense the micro-Doppler information of targets. A convolution neural network (CNN) is further implemented in the detection and classification of the human motion behaviors using this information. Both the convolution layers and architecture of CNNs are presented. The analysis on loss and accuracy of training results is also shown. The experimental result indicates a precise determination of human motion behavior detection using the proposed system.
Sheet Metal Forming (1991)

Part 1 Processes: uniaxial tension biaxial tension engineering deeper cups stretch-forming compressive instability blanking, bending and springback friction and surface topography lubrication temperature superplasticity in the press shop. Part 2 Materials: steel coated steels aluminium magnesium and titanium stainless steel and copper. Part 3 Tests: biaxial ductility tests deep drawing tests mixed tests buckling test hardness tests other useful tests.
Do suicidal ideation and behaviour influence duration of psychiatric hospitalization? (2002)

Suicidal ideation and behaviour are sometimes considered to be manipulative, with the intention of escaping from intolerable situations leading to prolonged hospitalization. The present study examined the length of hospitalization of those who had attempted suicide or had suicidal ideation compared to non-suicidal patients, as measured by the Health of the Nation Outcome Scales in two private psychiatric hospitals. Suicidal patients had a significantly shorter length of hospitalization, despite their significantly greater degree of psychiatric morbidity. Results indicated that it is erroneous to preclude inpatient care for those who are suicidal on the assumption that it will promote prolonged hospitalization.
A Convenient Preparation of Diamino Oligoethylene Glycols and Amino Polyethylene Glycols (1991)

Abstract Diamino oligoethylene glycols and amino polyethylene glycols were prepared in good yields by using the reaction of sodium diformamide with oligoethylene glycol or polyethylene glycol dichlorides or ditosylates followed by hydrolysis using ethanolic hydrochloride.
[Report of 2 cases of irreversible Horner syndrome after puncture of the internal jugular vein]. (1982)

Two cases are presented with irreversible Horner's syndrome after cannulation of the internal jugular vein during the intraoperative period. In the first case the cannulation succeeded only after several attempts. In the second case the cannulation succeeded the first time. All cannulations were performed by experienced anaesthesiologists. This means, that a strict indication for the cannulation of the internal jugular vein must be considered, because of the possibility of irreversible damage, even if the cannulation is performed by an experienced physician.
Integrated dead‐time compensation and elimination approach for model predictive power control with fixed switching frequency (2019)

To solve the problem of variable switching frequency in conventional model predictive power control (MPPC), many modified MPPCs with fixed switching frequency have been proposed. However, as the switching frequency increases, additional current harmonics caused by the dead‐time are added into the grid current. In this study, an integrated approach with compensation process and elimination process is proposed to eliminate the adverse effect of dead‐time. The elimination process with improving gate signals is applied when the phase current is large enough. In contrast, the compensation process is utilised when the phase current is relatively small and the elimination process is troubled by the misjudgement of the current polarity. The experimental results with different dead‐time and active power reference are provided to demonstrate the validity of the integrated approach. The integrated approach can further reduces the total harmonic distortion compared to the pure dead‐time compensation approach and almost removes the current harmonics caused by the dead‐time. Besides, the static error of the power caused by dead‐time is dramatically reduced by utilising the integrated approach.
Smoothed Linear Modeling for Smooth Spectral Data (2013)

Classification and prediction problems using spectral data lead to high-dimensional data sets. Spectral data are, however, different from most other high-dimensional data sets in that information usually varies smoothly with wavelength, suggesting that fitted models should also vary smoothly with wavelength. Functional data analysis, widely used in the analysis of spectral data, meets this objective by changing perspective from the raw spectra to approximations using smooth basis functions. This paper explores linear regression and linear discriminant analysis fitted directly to the spectral data, imposing penalties on the values and roughness of the fitted coefficients, and shows by example that this can lead to better fits than existing standard methodologies.
Koruma Alanlarında Yeni Yönetim Kategorileri ve Önemi (1996)

To protect the ecological balance and prevention of naturel resources from the unplanned intervention of human-being is only possible establishing conservation areas with co-operation at the national and the international levels. In order to ensure easy and effective co-operation, it must be appropriate to global standarts accepted in this field. International Union for Conservation of Nature and naturel resources (IUCN) have recently reneved its 10 category classification that establihed in 1978 and descented to 6 category system. For a contemporary management of conservation area, it is required an understanding of management which take care of the aim of establishment of such area and land useforms of in areas.
Membrane traffic in animal cells: cellular glycoproteins return to the site of Golgi mannosidase I. (1986)

The recycling of cellular glycoproteins to the site of Golgi mannosidase I, an enzyme of asparagine-linked oligosaccharide synthesis, was studied in K562 human erythroleukemia cells. Cells were metabolically labeled in the presence of deoxymannojirimycin, a reversible inhibitor of Golgi mannosidase I. This generates glycoproteins with immature oligosaccharides in their normal locations. Transport to the mannosidase I compartment was then assessed by testing for the conversion of oligosaccharides into mature forms during reculture without deoxymannojirimycin. Transferrin receptor (TfR) was acted on by mannosidase I during reculture, suggesting that it returned to the region of the Golgi complex where this enzyme resides. The slow rate of this transport (t1/2 greater than 6 h) implies that it is probably different than TfR movement during transferrin internalization (t1/2 = 10-20 min) and TfR transport to the sialyltransferase compartment in the Golgi complex (t1/2 = 2-3 h) (Snider, M. D., and O. C. Rogers, 1985, J. Cell Biol., 100:826-834). The total cell glycoprotein pool was also transported to the mannosidase I compartment with a half-time of 4 h. Because this transport is 5-10 times faster than the rate of de novo glycoprotein synthesis in these cells, it is likely that most of the glycoprotein traffic through the Golgi complex is composed of recycling molecules.
The Role of Surface .alpha.-Oxygen in Formation of Cation Radicals at Benzene Adsorption on ZSM-5 Zeolite (1994)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe Role of Surface .alpha.-Oxygen in Formation of Cation Radicals at Benzene Adsorption on ZSM-5 ZeoliteAlexander M. Volodin, Vadim A. Bolshov, and Gennady I. PanovCite this: J. Phys. Chem. 1994, 98, 31, 7548–7550Publication Date (Print):August 1, 1994Publication History Published online1 May 2002Published inissue 1 August 1994https://pubs.acs.org/doi/10.1021/j100082a026https://doi.org/10.1021/j100082a026research-articleACS PublicationsRequest reuse permissionsArticle Views170Altmetric-Citations26LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Construction of Chitosan— Gelatin—Hyaluronic Acid Artificial Skin <i>In Vitro</i> (2007)

To further enhance the properties of chitosan (Cs)-gelatin (Gel) scaffolds for skin tissue engineering, hyaluronic acid (HA) is introduced to the Cs-gel complex. Porous scaffolds composed of Cs, Gel, and HA are prepared using the freeze-drying method. The scaffold has an interconnected pore structure with two different pore size layers. The water uptake ability, flexibility, and biocompatibility of the scaffold are greatly increased with the incorporation of HA. To construct an artificial skin in vitro, fibroblasts and keratinocytes are co-cultured in Cs-Gel-HA scaffolds at an air-liquid interface. After 2 weeks of co-culture, the epithelial layer becomes progressively stratiform, including cubic perpendicularly oriented cells and a superficial layer of flattened cells. Immunohistochemical analyses confirmed the presence of laminin and type IV collagen, typical molecules of the basement membrane. The results of this study suggest that it is possible to construct a functional artificial skin in vitro and the Cs-Gel-HA scaffold is a promising matrix for skin tissue engineering.
Correction of energy-dependent systematic errors in dual-energy X-ray CT using a basis material coefficients transformation method (1997)

Computer simulation results from our previous studies showed that energy dependent systematic errors exist in the values of attenuation coefficient synthesized using the basis material decomposition technique with acrylic and aluminum as the basis materials, especially when a high atomic number element (e.g., iodine from radiographic contrast media) was present in the body. The errors were reduced when a basis set was chosen from materials mimicking those found in the phantom. In the present study, we employed a basis material coefficients transformation method to correct for the energy-dependent systematic errors. In this method, the basis material coefficients were first reconstructed using the conventional basis materials (acrylic and aluminum) as the calibration basis set. The coefficients were then numerically transformed to those for a more desirable set materials. The transformation was done at the energies of the low and high energy windows of the X-ray spectrum. With this correction method using acrylic and an iodine-water mixture as our desired basis set, computer simulation results showed that accuracy of better than 2% could be achieved even when iodine was present in the body at a concentration as high as 10% by mass. Simulation work had also been carried out on a more inhomogeneous 2D thorax phantom of the 3D MCAT phantom. The results of the accuracy of quantitation were presented here.
Glowing Contact Physics (2006)

There has been very little published research on glowing connections, especially their mechanisms and properties. In this study, oxide conductivity, surface x-ray maps, temperature measurements, and electrical waveforms were used to identify the structure and composition of glowing connections. It is shown that a glowing connection consists of a glowing molten liquid filament, which produced the orange glow that meanders on the surface of a solid copper oxide bridge that forms between two wires. Temperature and video measurements indicate that the glowing filament is in a liquid state. With the addition of oxide bridge resistivity measurements, the saw-tooth voltage pattern, typically seen in currents below 5Arms, has been explained. Also, when the glowing connection was slowly cooled, an impression of the glowing filament remained on the solid oxide. Subsequent SEM and x-ray mappings of this glow track revealed a track rich in copper, oxygen, and sulfur. This glow track explains the occasional low resistance path across the wires that can occur when the solid oxide bridge remains intact after cooling. Measurements in vacuum showed that oxygen was necessary to sustain the glowing filament even if there was a preexisting CuO oxide bridge present. Physical parameters affecting glow characteristics will be discussed; especially the semi-conducting nature of the copper oxide, and a model of the glowing contact, based on this data, that show some of the significant factors controlling the glow.
Wertbestimmung von Succus Liquiritiae in Arzneien, Zur Analytik von BISUC® (1975)

Abstract Succus Liquiritiae kann durch die Bestimmung des Triterpenaglucons Glycyrrhetinsäure und der Flavonaglucone Liquiritigenin und Isoliquiritigenin charakterisiert werden. Die Rückrechnung auf Glycyrrhizinsäure ist nicht eindeutig. Eine optimierte Glucosidspaltungsmethode und DC‐Trennung sowie die Stoffwerte (E ) wurden ermittelt und untere Grenzwerte zur Diskussion gestellt.
Controlled Synthesis of Porous Coordination‐Polymer Microcrystals with Definite Morphologies and Sizes under Mild Conditions (2014)

Herein, we report a facile and convenient method for the synthesis of the porous coordination polymer MOF-14 [Cu3 (BTB)2 ] (H3 BTB=4,4',4''-benzene-1,3,5-triyl-tribenzoic acid) as microcrystals with definite shapes and crystal facets controlled by the reaction medium at room temperature. The amount of sodium acetate added to the reaction system plays a crucial role in the shape evolution of MOF-14 from rhombic dodecahedrons to truncated rhombic dodecahedrons and cubes with truncated edges and then to cubes. The addition of a base could accelerate the formation rate of crystal growth and increase the supersaturation of crystal growth, thus resulting in the formation of MOF-14 cube crystals with high-energy crystal facets. The morphological evolution was also observed for HKUST-1 [Cu3 (BTC)2 ] (H3 BTC=1,3,5-benzenetricarbocylic acid) from octahedrons to cubes, thus verifying the probable mechanism of the morphological transformation. The gas-adsorption properties of MOF-14 with different shapes were studied and reveal that the porous coordination-polymer microcrystals display excellent and morphology-dependent sorption properties.
A Wireless Subway Collision Avoidance System Based on Zigbee Networks (2013)

 Abstract—A wireless subway collision avoidance system based on zigbee network is proposed in this paper. In the proposal, all the zigbee nodes are divided into two types, fixed nodes and mobile nodes. The fixed nodes are deployed in tree topology networks overlapped with each other along the subway tunnel; the mobile nodes are installed on the trains. The core idea is as soon as a fixed node establishing an association with a mobile node, the fixed node broadcasts the event with MAC address of the mobile node immediately. By listening the broadcasted messages, other nodes can deduce position of the mobile node currently being associated. In such a way, the overlapped zigbee networks can locate positions, detect abnormal stop of trains and broadcast these information to other trains in the tunnel. With each train knowing position of the train ahead of it, the collision can be avoided. The proposed zigbee network system is evaluated by ns-2, simulation results are presented.