gebhart/patrepeval huggingface dataset:
Targeting of the T-cell receptor zeta-chain gene in embryonic stem cells: strategies for generating multiple mutations in a single gene. (1992)

The T-cell receptor zeta chain is a member of a family of related proteins that play a critical role in coupling cell-surface receptors to intracellular signaling pathways. To study the role of zeta chain in T-cell ontogeny, we generated targeted mutations of the zeta-chain gene in murine embryonic stem cells. The mutant alleles are predicted to result either in a null phenotype or in the synthesis of a truncated protein capable of supporting T-cell-receptor surface expression but deficient in transmembrane signaling. Both of these targeting events were recovered in a single electroporation experiment with either coelectroporation or a combination deletion/truncation construct. Our results suggest that similar approaches could be used to generate multiple single mutations, modifications of more than one site within a gene, or subtle alterations that rely upon coconversion with the selectable marker gene.
A TRAP FOR THE DETECTION AND RECOVERY OF INSECTS IN STORED GRAIN (1967)

Abstract A trap that excludes grain kernels but permits the entry of grain beetles and mites is described. It may be used as a sampling device to detect insect infestations in stored grain. Sampling may be done with little disturbance to the surrounding grain and since the insects cannot escape, the trap can be left in position for prolonged periods.
Use of Case Management as a Revitalizing Theme in a Juvenile Justice Agency (1986)

Increasingly we are told that organizations and institutions are in crisis. They are less able to meet the expectations which their constitutents and clients place on them. They fail to create conditions for their own staff to do high-quality, productive work and are ill-suited to adapt to rapidly changing environments. Recent best sellers offer both diagnoses and prescriptions for these ills (Peters and Waterman, 1982; Peters and Austin, 1985; Bennis and Nanus, 1985; Kanter, 1983; Iacocca, 1984). In the following paper, we explore in depth one example of the joining of a new leader with a segmented, dispirited organization and look at dynamics of revitalitzation in a public agency. In particular, we examine the interactions between the leader and the staff and the role of a strategic theme as a vehicle for both directing and organizing the turn around. The first author served as a consultant to the Department of Juvenile Justice. The second author had just been appointed commissioner. We begin with a brief description of the agency at the time of the arrival of the new commissioner and explore her first 18 months, looking at the initial shaping of a strategic theme and the difficulties in translating the theme into concrete initiatives to alter the standard operating procedures of the organization. We conclude with a discussion of the learnings from this case.
Chemical/biological contaminant detector for aqueous environments: preliminary report (2002)

Paired surface transverse wave resonators operating near 500 MHz are being used as the sensing element in a chemical/biological detector capable of operating in water. Initially, the design of the surface transverse wave detector is discussed. Then, the major problems uncovered with the prototype detector are reviewed with an emphasis on solutions to these problems that will be implemented in a second-generation "smart" detector.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Fast computation of outage probability for cellular mobile radio systems (1995)

Abstract In this paper a new approximate method for the computation of outage probabilities in a mobile radio environment is proposed. It allows one to evaluate the performance of a mobile radio system in the presence of fading, in a very fast and accurate way, while maintaining a very good flexibility as to the application to different network environments. Coding is also considered as a possible choice, in order to increase the spectral efficiency of the system, which represents a major concern for the designers of cellular networks.
On Robustness of Cloud Speech APIs (2018)

The robustness and consistency of sensory inference models under changing environmental conditions and hardware is a crucial requirement for the generalizability of recent innovative work, particularly in the field of deep learning, from the lab to the real world. We measure the extent to which current speech recognition cloud models are robust to background noise, and show that hardware variability is still a problem for real-world applicability of state-of-the-art speech recognition models.
Homogeneous catalytic hydrogenation of unsaturated fats: Metal acetylacetonates (1966)

Abstract Hydrogenation of linseed and soybean methyl esters was achieved at 100舑180C, 100舑1000 psi H 2 and 0.05舑0.25 moles catalyst per mole of ester. The relative activity of metal acetylacetonates in decreasing order was: nickel (III), cobalt (III), copper (II) and iron (III). Reduction occurred readily in methanol solution but only slowly in dimethylformamide and acetic acid. No reduction occurred in the absence of solvents. Soybean oil was also hydrogenated rapidly with nickel (III) acetylacetonate in methanol, but in this system the triglycerides were converted to methyl esters. Nickel (III) acetylacetonate was the most selective catalyst toward linolenate hydrogenation. Methyl linoleate and linolenate hydrogenated with nickel(III) acetylacetonate were fractionated into monoenes, dienes and trienes. The cis monoenes separated in 62 to 68% yield had double bonds in the original position. The remaining trans monoenes had extensively scattered unsaturation. The dienes and trienes showed no conjugation, but some of the double bonds in the dienes were not conjugatable with alkali. Little stearate was formed.
A high-speed high-resolution low-phase noise oscillator using self-timed rings (2010)

A high-speed multi-phase oscillator based on self-timed ring is proposed. Self-timed rings (STR) are promising approach for designing high-speed serial links and clock generators. Indeed, the architecture of STR allows us to achieve high frequencies with multiphase outputs and their oscillation frequency is not only depending on the number of stages but also on the initial state of the ring. Moreover, this architecture allows us 3 dB phase noise reduction when, while keeping the same frequency, when the stage number is doubled. In this paper, we propose a method to design STR able to generate high-speed multi-phase outputs and we suggest a design flow for designing low-phase noise self-timed ring oscillators. All the electrical simulations and results have been performed using a CMOS 65nm technology from STMicroelectronics.
High performance spatial light modulators (1991)

The authors describe the structure, operation and functionality of a SLM in which the memory recircles in the ferroelectric liquid crystal cell above the silicon addressing circuitry. >
Solid-state dye lasers based on modified rhodamine 6G dyes copolymerized with methacrylic monomers (1996)

Modified rhodamine 6G molecules with polymerizable double bonds have been copolymerized with methacrylic monomers and the resulting polymers have been pumped at 337 nm with a N2 laser in a transversal configuration. The preparation of these new materials is described in detail and their lasing properties are evaluated. Important increases in photostability, with lasing efficiencies similar to those found for the parent dye rhodamine 6G in ethanol solution, have been obtained for some of these materials. Lifetimes (measured as an 80% efficiency drop) in excess of 20 000 shots at repetition rates of 2 Hz have been demonstrated. Strong dependence on pump repetition rate was observed. Possible mechanisms and processes responsible for the behavior of these materials are discussed. By using a rotating system where the sample is scanned in a continuous way, the laser output remained stable, with no sign of degradation, after 500 000 shots.
ChemInform Abstract: THE CHLORIDE CORROSION OF AUSTENITIC STAINLESS STEELS AND OF AN INCONEL ALLOY IN HOT ACIDIC MEDIA (1978)

Abstract Es wird das Korrosionsverhalten austenitischer rostfreier Stähle der Typen AISI 304, 3 l0 und 316 sowie einer Inconel‐Legierung in siedender Sproz. NaCl‐Lösung bei pH 2.5 sowie die Einflüsse von durch die Lösung geleiteten Gasen wie Luft, C12, N 2 und /oder H 2 S untersucht.
Ligand design and metal-ion recognition. Interaction of nickel(II) with 17- to 19-membered macrocycles containing O2N3 and O3N2 donor sets and the x-ray structure of the parent 17-membered macrocyclic ligand (1983)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTLigand design and metal-ion recognition. Interaction of nickel(II) with 17- to 19-membered macrocycles containing O2N3 and O3N2 donor sets and the x-ray structure of the parent 17-membered macrocyclic ligandKenneth R. Adam, Anthony J. Leong, Leonard F. Lindoy, Hyacinth C. Lip, Brian W. Skelton, and Allan H. WhiteCite this: J. Am. Chem. Soc. 1983, 105, 14, 4645–4651Publication Date (Print):July 1, 1983Publication History Published online1 May 2002Published inissue 1 July 1983https://pubs.acs.org/doi/10.1021/ja00352a021https://doi.org/10.1021/ja00352a021research-articleACS PublicationsRequest reuse permissionsArticle Views351Altmetric-Citations71LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
Nitrogen Reducing Solar Cells (1979)

The increasing awareness of the limits of our supplies of natural gas has created some interest in recent years in replacing existing methods of industrial ammonia synthesis either with less energy-demanding variants, or by altogether new methods of synthesis that would be independent of conventional energy sources. While it is fully recognized that the HABER-BOSCH Process of ammonia synthesis will probably never be fully replaced by other methods, it is nevertheless worthwhile to examine the feasibility of alternative approaches to the problem. Nature’s way of fixing nitrogen is one such alternative which obviously works and which in fact exhibits all desirable features of a process which, if it could be carried out on a large scale technically, could replace the HABER-BOSCH Process.
No Increased Risk of Spinal Cord Ischemia in Delayed AAA Repair Following Thoracic Aortic Surgery (2013)

This series does not demonstrate any evidence of increased risk of perioperative mortality or SCI in patients undergoing delayed AAA repair after prior thoracic aortic surgery.
Performance analysis of RAKE receivers with maximum a posteriori channel state estimation over time varying frequency selective finite state Markov fading channels (2002)

Time varying channels have memory due to the correlation between successive channel impulse responses. By using finite state Markov chains, this memory can be exploited to improve the receiver performance. A channel estimation scheme for time varying frequency selective fading channel is developed and used in a maximum ratio combining RAKE receiver for a QPSK WCDMA downlink. The receiver only requires a sequence of pilot symbols to start. The channel estimation algorithm models the amplitude as well as the phase of the recombined paths of the RAKE receiver and makes use of maximum a posteriori metrics and an efficient arrangement of Viterbi algorithms.
Method for crosslinking of resin and crosslinkable resin compositions with improved storage stability. (2004)

The method of effecting crosslinking of a resin comprises generating vinyl sulfonyl moieties in situ with the resin, the sulfonyl moieties then undergoing a reaction which effects crosslinking of the resin. The crosslinkable resin compn. comprises a polymer to be crosslinked, a liq. carrier for the polymer, nucleophilic groups and the vinyl sulfonyl precursor group capable of generating vinyl sulfonyl groups on loss of liq. carrier from the compn. The crosslinking reaction results from reaction of the vinyl sulfonyl moieties with nucleophilic groups in the resin compn. [on SciFinder (R)]
NEW SIMPLIFIED TECHNIC FOR LOCALIZATION OF FOREIGN BODY (1950)

IN RECENT years a multitude of methods for localizing foreign bodies has filled both the American and the foreign literature, but the majority require special localizing equipment. The methods described have been based on some form of localization or on electronic principles. One method of localization is based on the basic principle of parallax and similar triangles as popularized by Shenton.<sup>1</sup>The depth of the foreign body is determined from measurement of its shift on parallel x-ray plates when the tube head is shifted and a double exposure is made on the roentgenograms.<sup>2</sup>A second method is based on the principle of marking the skin with gentian violet at intervals of 1 inch (2.5 cm.), placing lead shot on adhesive tape along the same lines and taking a roentgenogram.<sup>3</sup>A third method is the localization of foreign bodies with a pointed hemostat under the fluoroscope. The electronic
Genotype A2/adw2 Strain of Hepatitis B Virus in Turkey. (2010)

The subtype is inconsistent with the previous data from Turkey; specifically, the identification of the A2/adw2 subtype of the hepatitis B virus in an inactive carrier is the first such case in Turkey. This finding suggests that the transmission of another genotype besides genotype D subtype ayw of the hepatitis B virus is possible in Turkey.
High Speed Casting of Sheet Grade Steel (1974)

Some types of strand guidances of continuous casting machine have been arranged below the mold, and their adaptability to the high-speed casting have been examined.The following results are obtained.1) The cooling plate set below the mold is a superior strand guidance method. But it's cooling ability is insufficient.2) The cooling grid is a satisfactory equipment for both slab supporting and slab cooling ability.3) Therefore, for the high-speed casting operations of sheet grade steel, the cooling grid or the combination of cooling plate and cooling grid is the most suitable method of slab guidance below the mold.
ChemInform Abstract: SYNTHESIS OF MONOTERPENOID Γ‐ AND Δ‐LACTONES VIA THE WITTIG‐HORNER REACTION (1980)

Abstract Wittig‐Horner‐Reaktion des (‐)‐Epoxyisodihydrocarvons (I) mit dem Ylid aus (II) liefert die isomeren Epoxyester (III).
Experimental Demonstration of H-PCE with BPG-LS in elastic optical networks (2013)

In the H-PCE architecture the mechanism to build the Traffic Engineering Database of the Parent PCE is not defined. This work validates the use of BGP-LS to feed the TED and compares two algorithms that use different amount of information.
Synthesis and photochemistry of the aqueous-soluble (.eta.5-C5H4CH2CH2NH3+)2Mo2(CO)6 complex. Generation of 19-electron complexes in aqueous solution (1992)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSynthesis and photochemistry of the aqueous-soluble (.eta.5-C5H4CH2CH2NH3+)2Mo2(CO)6 complex. Generation of 19-electron complexes in aqueous solutionAlfred Avey and David R. TylerCite this: Organometallics 1992, 11, 11, 3856–3863Publication Date (Print):November 1, 1992Publication History Published online1 May 2002Published inissue 1 November 1992https://pubs.acs.org/doi/10.1021/om00059a059https://doi.org/10.1021/om00059a059research-articleACS PublicationsRequest reuse permissionsArticle Views109Altmetric-Citations21LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Insulin Release and Inhibition of Fore-Stomach Motility in Sheep (1976)

Insulin Release and Inhibition of Fore-Stomach Motility in Sheep
Flat-band voltage hysteresis of MNOS structures (1970)

A shift of the flat-band voltage of metal–nitride–oxide–silicon (MNOS) elements connected with a hysteresis effect, is observed when voltage pulses exceeding a certain threshold amplitude are applied. The hysteresis behaviour is orientated in such a sense that the flat-band shifts to positive flat-band voltages with positive voltages applied, and to the reverse direction with negative voltages applied. The flat-band voltage shift is stable for voltages below the threshold voltage. Therefore, the flat-band state can be investigated without altering it. The shortest pulse times producing an effect are in the order of 1 μs. Elements with aluminium as a metal contact show a secondary effect, i.e. the flat-band voltage was changed to positive values with negative pulses. No considerable change in the course of the hysteresis effect was found at lower temperatures. Nach Spannungsimpulsen oberhalb einer bestimmten Schwellspannung und einer Mindestpulsdauer werden Flachbandverschiebungen an Metall–Nitrid–Oxid–Silizium(MNOS)-Elementen hervorgerufen, die einen Hysteresiseffekt bedingen. Die Flachbandverschiebung verläuft so, daß die Flachbandspannung nach positiven Spannungen zu positiven Werten verschoben ist, und entsprechend nach negativen Pulsspannungen zu negativen Werten. Diese Verschiebung ist bei Spannungen unterhalb der Schwellspannung stabil; daher kann der Flachbandzustand der Probe gemessen werden, ohne ihn zu verändern. Die kürzesten Pulszeiten, nach denen ein Effekt erreicht wird, liegen bei 1 μs. Elemente mit Aluminiumkontakt zeigen einen Nebeneffekt nach negativen Pulsspannungen, der Verschiebungen zu positiven Flachbandwerten ergibt. Bei tieferen Temperaturen wurde keine bemerkenswerte Änderung im Verlauf der Hysteresiskurve gefunden.
Formation of Short-Chain Fatty Acids from H <sub>2</sub> and CO <sub>2</sub> by a Mixed Culture of Bacteria (1981)

The biological utilization of CO(2) and H(2) for the formation of short-chain fatty acids was studied by using a mixed culture of bacteria. Optimization of a medium was carried out in continuous culture to identify limiting factors which controlled growth and production of organic acids. The optimal pH for growth and acid production was 7.0 at 37 degrees C; the maximal cell concentration obtained was 5.9 g of cells per liter (dry weight), and the maximal amount of volatile acids formed was 4.7 g/liter, with acetic acid as the predominant acid. With the optimized medium, it was found that the rate of transfer of hydrogen or carbon dioxide, or both, from gas to liquid was the limiting factor which controlled growth and production of acids.
The insulin-like growth factor system in human peritoneal fluid: its effects on endometrial stromal cells and its potential relevance to endometriosis. (1994)

Peritoneal fluid (PF) lines the abdomen and pelvis and is believed to contain growth factors that stimulate endometriosis, a benign gynecological condition associated with pelvic pain and infertility, in which endometrial cells proliferate and differentiate on the pelvic peritoneum, outside of their normal location within the uterus. In this study, we examined the insulin-like growth factor (IGF) system in seven paired samples of PF and serum from normally cycling women and examined the mitogenic potential of this fluid on cultured endometrial stromal cells. IGF-I, IGF-II, and IGF-binding protein-1 (IGFBP-1), -2, -3, and -4 were identified in PF by immunoassays. PF IGF levels, determined by RIA, were approximately 60% of paired serum levels, and PF levels of IGFBP-2 and IGFBP-3, determined by Western ligand blotting and RIA, respectively, were approximately half of their serum concentrations. IGFBP-4 was barely detectable by Western ligand blotting in PF, and levels of IGFBP-1, determined by immunoassay, were not appreciably different in PF and serum. Incubation of [125I]IGF-II with serum and PF and subsequent size-exclusion chromatography at neutral pH revealed approximately equal incorporation of radiolabel in the IGFBP regions of 150 and 44 kilodaltons (kDa) in serum and primarily in the 44-kDa region in PF. RIA of IGFBP-3 in the IGFBP regions of column effluent revealed that the majority of IGFBP-3 was in the 150-kDa region in both serum and PF, suggesting the presence of the ternary complex in PF. Western ligand blotting of column effluent samples revealed 37-/43-kDa IGFBP-3 primarily in the 150-kDa complex in serum and a marked reduction in the amount of the 37-/43-kDa IGFBP in PF. Western immunoblotting of column effluent with IGFBP-3 antiserum revealed immunoreactive IGFBP-3 forms of 37-43 kDa (major) and 28 kDa (minor) in serum and almost exclusively the 28-kDa band in PF, suggesting that IGFBP-3 in PF may be proteolytically processed. The presence of an IGFBP-3 protease was confirmed using [125I]IGFBP-3 as substrate and was not appreciably present in paired serum samples. Inhibitor profiles demonstrated that this protease is a metal-independent serine protease, and its approximate relative molecular mass was estimated to be 69 kDa, determined by size-exclusion chromatography. The mitogenic potential of IGF peptides and PF was assessed on cultured endometrial stromal cells to test the hypothesis that IGFs in PF may stimulate the growth of endometrium in the pelvic cavity, for example in the disorder of endometriosis.(ABSTRACT TRUNCATED AT 400 WORDS)
Characteristics of electron beam welded CA6NM (2013)

In this study, the viability of thick-gauge section assembly for hydroelectric turbine manufacture was considered by electron beam welding CA6NM martensitic stainless steel, a widely utilized hydro-turbine cast material. Particularly, bead-on-plate trials on 60 mm-thick CA6NM plates were carried out using a 42 kW high vacuum electron beam welding system. The influence of the heat input, beam position, beam oscillation (XSF-YSF), and in-situ pre-heating conditions on the characteristics of the weldments, such as the bead geometry, weld integrity, fusion zone and HAZ microstructures and hardness were evaluated. A relationship between the welding parameters and the resulting depth of penetration was established. A methodology for in-situ heating of the thick-gauge section prior to welding was developed and evaluated for reducing welding defects in CA6NM.