gebhart/patrepeval huggingface dataset:
Magnetization studies of Ho/Y superlattices: Role of magnetoelastic coupling effects (1996)

Ho films and Ho/Y superlattices were fabricated and characterized structurally and magnetically. Anomalies in the magnetization vs field applied along the easy axis identify magnetic phase transitions, as found in bulk Ho, but with enhanced critical fields. The critical fields required to magnetize the samples vary systematically with the total Ho fraction in a manner that is shown to be consistent with the assumption that the Ho and Y layers are magnetoelastically coupled. \textcopyright{} 1996 The American Physical Society.
SYNTHESIS, X-RAY CRYSTALLOGRAPHY, MOLECULAR DOCKING AND BIOLOGICAL SCREENING OF 2-AMINOPHENOL BASED SCHIFF BASES (2013)

Schiff bases, 2-{[(2-hydroxyphenyl)methylidene]amino}phenol (4) and 2-{[3-4-(dimethylamino)phenyl-2-propenylidene]amino}phenol (5), have been synthesized by the condensation of 2-aminophenol (1) with 2-hydroxybenzaldehyde (2) and 4-dimethylaminocinnamaldehyde (3), respectively. They showed good lipoxygenase inhibition and antioxidant activities, as compound 4 showed potent antioxidant activity. The products also showed good activities against Gram-positive: S. intermedius, B. subtilis and S. aureus, and Gram-negative: E. coli and S. typhi bacteria, as compounds 5 and 4 are excellent active against B. subtilis and S. typhi, respectively. These good to potent activities may be due to the presence of free hydroxyl and amino groups. They showed non-significant urease inhibition activity.
The Prevalence of Prostatitis-Like Symptoms in China (2009)

Prostatitis-like symptoms are a multifactorial problem affecting men of all ages (15 to 60 years) and demographics, and the prevalence is high in China. The syndrome is closely related to alcohol consumption, cigarette smoking, frequent intercourse, as well as fatigue, pressure and too little sleep. These findings suggest that risk factors for this condition are largely modifiable and highlight potential targets for future prevention.
Spatial localization of absorbing bodies by interfering diffusive photon-density waves (1993)

The use of the destructive interference of diffusive photon-density waves for the localization of an absorbing (and scattering) body in a scattering medium was studied. The objectives of this approach in the reflectance mode were as follows: first, to reduce sensitivity to absorption features occurring in superficial layers while sensitivity to bodies lying deeper is maintained; second, to establish a confined depth region of maximum sensitivity in which the distance of an absorbing body could be determined through phase measurement. Intensity and phase data were acquired with a modified frequency-domain spectrometer at modulation frequencies up to 600 MHz as an absorbing body was moved in three dimensions. The experimental results are compared with simulations based on a numerical solution of a time-dependent photon-diffusion equation.
Characterization of Factor V activation intermediates. (1984)

Bovine Factor V was partially activated with bovine beta-thrombin and activation intermediates, and end products were isolated either by column chromatography under nondenaturing conditions or electroelution from slab gels following electrophoresis in dodecyl sulfate or both. Electrophoresis of partially activated single-chain Factor V (Mr = 330,000) revealed intermediates designated B (Mr congruent to 205,000) and C (Mr congruent to 150,000), plus end products designated C1 (Mr congruent to 120,000), D (Mr congruent to 94,000), E (Mr congruent to 74,000), F (Mr congruent to 71,000), and G (Mr congruent to 31,000). All components except C1 were visualized readily by staining with Coomassie blue. C1, however, did not stain with this dye but was readily visualized with the Schiff-periodate or silver staining procedures. Chromatography of samples of partially activated Factor V on QAE (quaternary aminoethyl)-cellulose in Ca2+ yielded fractions consisting, respectively, of B plus C and B plus D. Both were biologically active, but the former pair required further exposure to thrombin to yield activity, whereas the latter did not. Either pair, when treated with EDTA, lost activity and could be resolved by further chromatography on QAE-cellulose into isolated components B, C, and D. Activity was recovered upon reconstitution of the pairs in Ca2+, suggesting that B plus C or B plus D comprise two subunit proteins, both subunits of which are required for biological activity. Gel electrophoretic analysis of isolated B and C, after further exposure to thrombin, indicated that B is the precursor of end products C1, E, and G, whereas C is the precursor of D and F. Conventional NH2-terminal sequence analysis and amino acid composition analysis indicated that C and D share the same NH2 terminus with Factor V and that the weighted composition of B plus C is the same as Factor V. Microsequence analysis of C1 and E indicated that C1 has the NH2-terminal sequence of intermediate B, which differs from that of end product E. These results indicate that: 1) a single cleavage of Factor V yields B and C from the COOH and NH2 termini, respectively, of the parent; 2) the pair B and C constitute a Ca2+-stabilized protein of two subunits, both of which are required for subsequent expression of biological activity; 3) the precursor-product relationship between B and C and the end products of activation are: B----C1 + E + G, and C----D + F; and 4) end product D is derived from the NH2 terminus of C, and end product C1 is derived from the NH2 terminus of B.
UNRAVELING THE PROBLEMS OF PROTEIN - SACCHARIDE INTERACTIONSVIA COMPUTATIONAL CHEMISTRY (2007)

Detailed knowledge of interactions between proteins and small
molecules is important for understanding of signifi- cant
processes in organisms. Saccharides and various glycoconjugates
play a significant role in many host-patho- gen interactions.
Lectins are sugar-binding proteins of non-immunoglobulin nature
that agglutinate cells or pre- cipitate glycoconjugates. Their
specificity is usually de- fined by the monosaccharides or
oligosaccharides that are best at inhibiting the agglutination
or precipitation the lectin causes. Lectins are of interest
because of their wide variety of properties and potential
applications (pharma- cology, immunology, cancer therapy,
agriculture ...). Since host carbohydrates have been known for
many years to constitute specific attachment sites for pathogen
protein receptors, there is a great interest in structure-func-
tion studies of bacterial proteins enabling the pathogen at-
tachment to host glycans. However, only a limited number of
their complexes with receptors have been characterizedby
crystallography [1]. The molecular modeling methods can help in
the study of the complexes. The study will be focused on
docking of a set of monosaccharides into two different lectins
originally from bacteria Pseudomonas aeruginosa (PA-IIL) [2]
and Ralstonia solanacearum (RS-20L) using the Dock v. 6.0
program.
Synthesis, Characterization, and Photophysical Studies of New Blue Light Emitting Segmented Copolymers (2001)

A series of new segmented copolymers containing m-phenylene in the chromophore unit have been synthesized by Wittig condensation. They are readily soluble in organic solvents and have high photoluminescence quantum yields in chloroform. Face-to-face π-stacking in the solid state is limited or prevented by molecular nonlinearity due to the meta-linkage and by the presence of a bulky tert-butyl group in the chromophores. Single-layer electroluminescence devices with an ITO/polymer/Ca−Al configuration emitted in the blue region (470−490 nm) for all of these systems.
The Incidence and Management of Nonalcoholic Fatty Liver Disease in Potential Kidney Donors. (2014)

Purpose: To determine the incidence and management of NAFLD and NASH in prescreened living kidney donors. Methods: Between January 2010 and December 2013, 399 potential kidney donors were registered and underwent blood and HLA typing at our institution. Of these potential donors, 106 completed the evaluation including computed tomography (CT) scan. Diagnosis of NAFLD was based upon presence of hepatic steatosis on imaging using liver to spleen ratio (L:S ratio, <1.1) criteria, and absence of anti-HCV and HBsAg, and negative history of excessive alcohol use, and secondary causes of hepatic steatosis or other causes of elevated serum ALT or AST (LFTs). 14 patients (13.2%) had elevated ALT, TB or AST, and 10 patients (9.4%%) had hepatic steatosis noted on CT. 6 patients (5.6%) had both abnormal LFTS and hepatic steatosis on imaging. Results: From the group with abnormal LFTs or imaging, 8 patients (44%) proceeded to donation. Patients with mild steatosis and normal BMI and LFTs were allowed to donate (2). 2 patients had normalization of LFTs without intervention. 3 patients with mild transaminase elevation and/or mild steatosis on imaging were counseled about diet and weight loss, and allowed to donate once transaminases normalized. Average weight loss was 8 lbs. A patient with persistent abnormal LFTs, but normal BMI and imaging was referred for a liver biopsy examination. Liver biopsy showed mild (5-10%) steatosis without signs of NASH and he was cleared for donation. 10 patients were not cleared for donation. 4 patients were ruled out for medical or anatomic issues without work up of for liver disease. One patient was referred to hepatology and but had improvement in LFTs after weight loss, however was ruled out due to the presence of nephrolithiasis. 5 patients were excluded based upon on the presence of significant liver disease. One patient was found to have alcohol abuse as likely contributing factor for liver disease. 2 patients did not proceed with their evaluation after being referred to hepatology for further work up and liver biopsy. 2 patients had NASH without cirrhosis on liver biopsy and were excluded from donation. Conclusion: 10 - 13% of healthy potential living kidney donors are found to have NAFLD based upon either elevated ALT/AST or imaging during work up. Patients with mild transaminase elevation or mild steatosis on imaging are likely ok to proceed with donation, especially if diet and weight loss leads to normalization of ALT and AST. Patients with significant steatosis on imaging or persistent elevation
The History and Growth of IBM's DB2 (2012)

IBM's Database 2 (DB2) relational database management system (RDBMS) shipped in the early 1980s and drove billions of dollars of revenue to IBM and other firms within its first decade. The product spawned a wealth of add-on tools, shaped the future of mainframe computing, and provided independent software vendors with a strong, reliable, and scalable platform for mission-critical applications. Today, DB2 spans multiple operating systems and is widely deployed across a broad spectrum of industries. This article explores the beginnings of DB2 and traces its rise to prominence.
Realizing standby operation of a television with zero energy consumption: Options and issues of the ultimate energy saving standby mode on the example of a recent flat TV model (2009)

The energy consumption of consumer electronics while in off state is a never ending discussion and leads to always improving and more complex solutions. This paper shows our experiences with a concept completely removing such consumption while maintaining the most important remote control functionality.
Observations of Galactic Radiation at Frequencies of 1200 and 3000 Mc/s (1951)

Measurements are described of galactic radiation at frequencies of 1210 and 3000 Mc/s. The results provide extensions of previous radio emission spectra by more than 2½ octaves. The intensity of radiation from near the galactic centre was measured and an estimate made of the direction of the maximum of such radiation. A new " discrete source " of peculiar spectrum was discovered very close to the centre of the Galaxy. Evidence suggests that the power output of this and some other sources in the radio spectrum may exceed the total power output of the Sun. Radiation was also observed from the direction of the Crab Nebula, from the known " radio source " in Centaurus, and from the Moon. Two nebulae (M 31 and NGC 7293) were investigated with negative results. The spectra of two sources are given between the limits 18.3 and 1200 Mc/s.
Metabolic Gaps In Bone Formation May Be A Novel Marker To Monitor The Osseous Metastasis Of Prostate Cancer (2002)

Different bone formation markers seem to be sensitive clinical markers for judging the response to therapy of prostate cancer metastasized to bone.
Prediction of accommodative optical response in prepresbyopic subjects using ultrasound biomicroscopy (2015)

Ultrasound biomicroscopy parameters can, on average, predict accommodative optical responses with SDs of less than 0.55 D using linear regressions and 95% CIs. Ultrasound biomicroscopy can be used to visualize and quantify accommodative biometric changes and predict accommodative optical response in prepresbyopic eyes.
67‐2: A 510‐ppi 8K x 4K LTPS TFT‐LCD with 120‐Hz Frame‐Rate Driving (2016)

We have developed a 510[ppi] 8K4K LTPS TFT‐LCD with 120[Hz] frame rate driving. High mobility of the TFT allows simple panel configuration. Shrinkage of the channel width and thinner insulator for the storage capacitor allow high display qualities including uniformity of transmittance and small crosstalk.
Negative feedback neuroendocrine control of the inflammatory response in rats (1995)

We describe that an ongoing inflammatory response at one site (produced by complete Freund's adjuvant injection in the hindpaw) produces a negative feedback inhibition on plasma extravasation, produced by perfusion of the inflammatory mediator, bradykinin (160 nM), at a second site (the knee joint). This negative feedback process is abolished in rats that have been neonatally treated with capsaicin to deplete most of their unmyelinated primary afferent fibers, which suggests that this negative feedback process is mediated by activation of primary afferent fibers. Electrical stimulation of the hindpaw at intensities that excite C-fibers also inhibited bradykinin-induced plasma extravasation. Stimulation at intensities that only excite A-fibers had no effect on bradykinin-induced plasma extravasation. Platelet activating factor-induced plasma extravasation, which is not dependent on the innervation of the joint, was not inhibited by stimulation of C-fibers from the hindpaw. Acute surgical interruption of the lumbar sympathetic outflow to the hind limb (the paravertebral ganglia between L2 and L4) did not attenuate the depression of bradykinin-induced plasma extravasation produced by C-fiber stimulation. This indicates that the depression is not mediated by activity in the sympathetic outflow. Transection of the spinal cord, hypophysectomy, inhibition of corticosterone synthesis, and adrenalectomy (but not adrenal medullectomy) all prevented the inhibition of BK-induced plasma extravasation by electrical simulation, indicating that the negative feedback inhibition on plasma extravasation is dependent on an intact neuraxis and an intact hypothalamic-pituitary-adrenocortical axis. In summary, our data demonstrate a negative feedback inhibition of an inflammatory process, which is elicited by stimulation of C-fiber afferents.(ABSTRACT TRUNCATED AT 250 WORDS)
Calibration of optical lever sensitivity for atomic force microscopy (1995)

Accurate force determinations in atomic force microscopy require the precise measurement of cantilever deflections. A limiting factor in making these measurements is the calibration of the optical lever detection system, particularly when the tip cannot be pressed against a hard surface. Here we show that, for a given instrument, a fixed displacement of the photodiode detector produces a change in the detector voltage that correlates strongly with optical lever sensitivity. This provides a simple method for optical lever sensitivity calibration not requiring contact of the tip with any surface. The data also suggest that differences in the shape of the laser spot on the photodiode are a major source of variability in optical lever sensitivity.
A high‐temperature chemical kinetic model for primary reference fuels (2007)

Abstract A chemical kinetic mechanism has been developed to describe the high‐temperature oxidation and pyrolysis of n ‐heptane, iso ‐octane, and their mixtures. An approach previously developed by this laboratory was used here to partially reduce the mechanism while maintaining a desired level of detailed reaction information. The relevant mechanism involves 107 species undergoing 723 reactions and has been validated against an extensive set of experimental data gathered from the literature that includes shock tube ignition delay measurements, premixed laminar‐burning velocities, variable pressure flow reactor, and jet‐stirred reactor species profiles. The modeled experiments treat dynamic systems with pressures up to 15 atm, temperatures above 950 K, and equivalence ratios less than approximately 2.5. Given the stringent and comprehensive set of experimental conditions against which the model is tested, remarkably good agreement is obtained between experimental and model results. © 2007 Wiley Periodicals, Inc. Int J Chem Kinet 39: 399–414, 2007
Reaction of Group IV transition metal tetraorganyls with carbon monoxide (1987)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTReaction of Group IV transition metal tetraorganyls with carbon monoxideKarl Heinz. Thiele, Christian. Krueger, Angela. Sorkau, Irma. Oetvoes, Tamas. Bartik, and Gyula. PalyiCite this: Organometallics 1987, 6, 11, 2290–2293Publication Date (Print):November 1, 1987Publication History Published online1 May 2002Published inissue 1 November 1987https://pubs.acs.org/doi/10.1021/om00154a004https://doi.org/10.1021/om00154a004research-articleACS PublicationsRequest reuse permissionsArticle Views103Altmetric-Citations7LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
Zoledronic acid delays the onset of skeletal‐related events and progression of skeletal disease in patients with advanced renal cell carcinoma (2004)

We read with interest the article published by Lipton et al.1 The authors established in their article that zoledronic acid demonstrated significant clinical benefit in patients with bone metastases from renal cell carcinoma (RCC). In particular, they retrospectively analyzed 74 patients with RCC who were enrolled in a Phase III study of zoledronic acid therapy for patients with bone metastases from solid tumors. In RCC patients, zoledronic acid was found to significantly reduce the percentage of patients who developed skeletal events. The benefit of zoledronic acid in patients with RCC was demonstrated in the median time to the first skeletal event and the median time to the first pathologic fracture, both of which were note to have increased significantly in patients who were treated with zoledronic acid. We found these results very interesting but were not surprised by them. RCC has been an attractive target for clinical trials of angiogenesis inhibitors because it is a highly vascular tumor and is known to produce proangiogenic cytokines such as vascular endothelial growth factor (VEGF).2 However, the biology of RCC appears to be extremely intricate, because some angiogenesis inhibitors are produced by the tumors themselves.3 Recently, we published our results concerning the antiangiogenic properties of zoledronic acid in patients with bone metastases.4 We prospectively collected blood samples from patients with bone metastases who were treated with zoledronic acid. The analysis demonstrated a statistically significant decrease, compared with basal values, in VEGF levels at 1 day, 2 days, 7 days, and 21 days after zoledronic acid infusion. Moreover, it was able to also induce a significant, although transient, decrease of serum platelet-derived growth factor levels. To our knowledge, the biologic mechanism of action of bisphosphonates on the angiogenesis network is not clearly understood but we can surmise that zoledronic acid and other bisphosphonates may activate several antiangiogenic cytokine patterns and cascades, as demonstrated by clinical and preclinical studies.5 All these findings suggest that the evident effect of zoledronic acid on bone progression in RCC patients most likely should be related to the antiangiogenic properties of these drugs. Moreover, in the article by Lipton et al., the median overall survival demonstrated a trend toward favoring zoledronic acid, even if the difference did not achieve statistical significance compared with placebo, most likely because of the small number of patients evaluated. In addition, these findings confirm the antineoplastic properties of zoledronic acid and may represent a basis for evaluating the anticancer efficacy of this drug, at least in the subset of patients with RCC.
Control of a doubly-fed induction wind generator under unbalanced grid voltage conditions (2005)

Wind energy is often installed in rural, remote areas characterized by weak, unbalanced power transmission grids. In induction wind generators, unbalanced three-phase stator voltages cause a number of problems, such as overheating, over-current, and stress on the mechanical components from torque pulsations. Therefore, beyond a certain amount of unbalance, induction wind generators are switched out of the network. This can further weaken the grid. In doubly-fed induction generators, control of rotor currents allows for adjustable speed operation and reactive power control. In addition, it is possible to control the rotor currents to correct for the problems caused by unbalanced stator voltages, including torque pulsations and unbalanced stator currents. This paper presents a novel voltage mode controller design for a doubly-fed induction generator that provides variable speed, reactive power control. Also, under stator voltage unbalance conditions, the proposed control eliminates torque pulsations and draws more balanced currents from the utility
Recrawl scheduling based on information longevity (2008)

It is crucial for a web crawler to distinguish between ephemeral and persistent content. Ephemeral content (e.g., quote of the day) is usually not worth crawling, because by the time it reaches the index it is no longer representative of the web page from which it was acquired. On the other hand, content that persists across multiple page updates (e.g., recent blog postings) may be worth acquiring, because it matches the page's true content for a sustained period of time.