gebhart/patrepeval huggingface dataset:
External Abdominal Aortic Compression: A Study of a Resuscitation Manoeuvre for Postpartum Haemorrhage (1994)

External aortic compression is an emergency manoeuvre proposed to reduce postpartum haemorrhage and permit time for resuscitation and control of bleeding. To assess this technique, a prospective study was performed on twenty normal non-bleeding parturients. The abdominal aorta was compressed by firm pressure with a closed fist just above the umbilicus. Leg and arm arterial blood pressures were measured and femoral artery pulsation felt before, during and after compression. Leg blood pressure was completely obliterated in 55% and significantly reduced (P < 0.01) in a further 10% of subjects. All of these subjects with reduced or absent leg blood pressure also had obliteration of the femoral pulse with compression. Systemic arterial blood pressure was not significantly elevated by successful aortic occlusion. Discomfort with the manoeuvre was significantly increased (P < 0.05) in the group of subjects that had successful aortic occlusion. It is recommended that external aortic compression be considered in severe life-threatening postpartum haemorrhage, particularly during stabilisation or transport of the patient. This simple manoeuvre may be used as an adjunct to other measures and could prove of benefit, especially in locations or situations where advanced medical assistance is geographically or temporally removed.
[Rh(7‐SPh‐8‐Me‐7, 8‐C<sub>2</sub>B<sub>9</sub>H<sub>10</sub>)(PPh<sub>3</sub>)<sub>2</sub>]: ein neuer Carboran‐Rhodiumkomplex mit erhöhter Aktivität bei der Hydrierung von 1‐Alkenen (1996)

Achtmal schneller als [RhCl(PPh 3 ) 3 ] katalysiert der Rhodacarborankomplex 1 die Hydrierung von 1‐Hexen. Das Schwefelatom, das an ein Kohlenstoffatom der offenen Flache gebunden ist, begünstigt die Wechselwirkung des Rhodiumzentrums mit den reaktiveren B‐H‐Ecken der offenen Fläche. magnified image
Evidence of hydrodynamic instability over a liner in a duct with flow (2009)

Lined ducts are widely used to reduce noise radiation from ducts, from air conditioning systems to turbofan engines. Liners may sustain some instabilities although there is no definite knowledge on that subject. Some analytical studies based on simple flow models have predicted the existence of unstable hydrodynamic modes, but their prediction capa-bility for realistic conditions is difficult to assess. Experimental evidence of the existence of instable modes in realistic flow conditions exist but is rare. While large increase in acoustic transmission across a lined part of ducts have been measured in the past, the flow itself over the liner has never been investigated. In the present paper an experimental study of the flow over a liner is made in such a configuration where the acoustic transmission is large, and evidence of an underlying hydrodynamic instability is provided, based on optical flow measurements. I.
ChemInform Abstract: Oxide‐Dependent Deposition and H2‐Promoted Aggregation of Organorhodium Complexes. (1986)

Abstract Silica and alumina are used for chemical attachment to reactive organometallic complexes.
The Hungry Stomach: Physiology, Disease, and Drug Development Opportunities (2011)

During hunger, a series of high-amplitude contractions of the stomach and small intestine (phase III), which form part of a cycle of quiescence and contractions (known as the migrating motor complex, MMC), play a "housekeeping" role prior to the next meal, and may contribute toward the development of hunger. Several gastrointestinal (GI) hormones are associated with phase III MMC activity, but currently the most prominent is motilin, thought to at least partly mediate phase III contractions of the gastric MMC. Additional GI endocrine and neuronal systems play even more powerful roles in the development of hunger. In particular, the ghrelin-precursor gene is proving to have a complex physiology, giving rise to three different products: ghrelin itself, which is formed from a post-translational modification of des-acyl-ghrelin, and obestatin. The receptors acted on by des-acyl-ghrelin and by obestatin are currently unknown but both these peptides seem able to exert actions which oppose that of ghrelin, either indirectly or directly. An increased understanding of the actions of these peptides is helping to unravel a number of different eating disorders and providing opportunities for the discovery of new drugs to regulate dysfunctional gastric behaviors and appetite. To date, ghrelin and motilin receptor agonists and antagonists have been described. The most advanced are compounds which activate the ghrelin and motilin receptors which are being progressed for disorders associated with gastric hypomotility.
Localized molecular orbitals for polyatomic molecules. I. A comparison of the Edmiston-Ruedenberg and Boys localization methods (1974)

The Edmiston-Ruedenberg (ER) and Boys localization methods are compared for a number of boron hydrides and carboranes. The Boys localization equations are solved explicitly for the two-orbital case and an iterative procedure for the multidimensional case is presented. The Boys analogs of Taylor's [J. Chem. Phys. 48, 2385 (1968)] ER equations are derived and the second-order term is converted into a symmetrized quadratic form which is analogous to the ER equations of Switkes et al. [J. Am. Chem. Soc. 92, 3847 (1970)]. A limited second-derivative test is employed in order to determine the nature of the convergence, and a transformation based on it is defined which successfully resolves structural ambiguities to which the standard two-orbital transformation procedure is subject. The Boys and ER localization methods are in at least qualitative agreement for all molecules except 1,2-C2B4H6, where the Boys localization yields a structure with fractional bonds and no open three-center B–C–B bonding. Previous ER localizations of 1,2-C2B4H6 resulted in two open B–C–B three-center bonds and no fractional bonding.
Role of Serum Albumin in Lipemia Clearing Reaction (1953)

Data are presented to show that purified serum albumin enhances the lipemia clearing reaction, probably by binding the fatty acids produced which, if not removed, are capable of inhibiting the reaction. Evidence that albumin is not the only cofactor in the clearing reaction is presented.
Evaluating the Rheological and Tribological Behaviors of Coconut Oil Modified with Nanoparticles as Lubricant Additives (2019)

In metal-forming processes, the use of lubricants for providing desirable tribological conditions at the tool–workpiece interface is critical to increase the material formability and prolonging tool life. Nowadays, the depletion of crude oil reserves in the world and the global concern in protecting the environment from contamination have renewed interest in developing environmentally-friendly lubricants derived from alternative sources such as vegetable oils. In the present study, the rheological and tribological behavior of coconut oil modified with nanoparticle additives was experimentally evaluated. Two different nanoparticle additives were investigated: Silicon dioxide (SiO2) and copper oxide (CuO). For the two conditions, nanoparticles were dispersed at different concentrations within the coconut oil. The effects of concentration and shear rate on the viscosity were evaluated and the experimental data was compared with conventional models. A custom-made tribotester was used to evaluate the effect of concentration on the tribological performance of the nano-lubricants. The experimental results showed that wear volume loss was lowered by 37% and 33% using SiO2 and CuO nanoparticles, respectively. Furthermore, the addition of SiO2 and CuO nanoparticles decreased the coefficient of friction (COF) by 93.75% and 93.25%, respectively, as compared to coconut oil without nanoparticles.
Updated radiative forcing estimates of 65 halocarbons and nonmethane hydrocarbons (2001)

The direct radiative forcing of 65 chlorofluorocarbons, hydrochlorofluorocarbons, hydrofluorocarbons, hydrofluoroethers, halons, iodoalkanes, chloroalkanes, bromoalkanes, perfluorocarbons and nonmethane hydrocarbons has been evaluated using a consistent set of infrared absorption cross sections. For the radiative transfer models, both line‐by‐line and random band model approaches were employed for each gas. The line‐by‐line model was first validated against measurements taken by the Airborne Research Interferometer Evaluation System (ARIES) of the U.K. Meteorological Office; the computed spectrally integrated radiance of agreed to within 2% with experimental measurements. Three model atmospheres, derived from a three‐dimensional climatology, were used in the radiative forcing calculations to more accurately represent hemispheric differences in water vapor, ozone concentrations, and cloud cover. Instantaneous, clear‐sky radiative forcing values calculated by the line‐by‐line and band models were in close agreement. The band model values were subsequently modified to ensure exact agreement with the line‐by‐line model values. Calibrated band model radiative forcing values, for atmospheric profiles with clouds and using stratospheric adjustment, are reported and compared with previous literature values. Fourteen of the 65 molecules have forcings that differ by more than 15% from those in the World Meteorological Organization [1999] compilation. Eleven of the molecules have not been reported previously. The 65‐molecule data set reported here is the most comprehensive and consistent database yet available to evaluate the relative impact of halocarbons and hydrocarbons on climate change.
Spectrum sharing optimization model for multiuser linear-precoded OFDM UWB systems (2012)

In this paper, we investigate spectrum sharing and multiple access problems for the high-rate ultra-wideband (UWB) systems. Based on the use of the linear precoded orthogonal frequency division multiplexing (LP-OFDM) proposed as an evolution of the well known multi-band OFDM (MB-OFDM) solution supported by the WiMedia Alliance for future high-rate UWB systems, the objective of this paper is to study a multiuser optimization spectrum sharing scheme for LP-OFDM UWB systems. This optimization study leads to a novel multiple access solution for the high-rate UWB systems. Simulation results demonstrate the efficiency of the use of the LP-OFDM transmission technique in the multiuser spectrum sharing scheme. Besides, the novel LP-OFDM multiuser spectrum sharing solution shows its capacity to provide a good tradeoff between the QoS support of the high-priority users and the fairness between the competing users.
Modification of Programs CHIEF and CID to Compute Sound Radiation from an Arbitrary Body with Mixed Boundary Conditions (1991)

Abstract : The computer program CHIEF developed over the last two decades by Naval Ocean Systems Center, San Diego, has recently been modified to allow the computation of sound radiation from arbitrarily shaped body where the normal velocity is prescribed on only part of its surface while one or two locally reacting complex impedances are assumed to cover the remainder of the surface. These impedances can range in value from zero to essentially infinity with any complex value in between. Results of some computations of far-field directivity pattern and radiation loading on simple shaped radiators with the mixed boundary conditions were compared with results available in the literature with generally good agreement. (Author)
A critical role for VEGF secreted by Dendritic cells (DCs) in priming T helper 2 (Th2) development in response to specific stimuli (2008)

Asthma is an inflammatory disease of the small airways caused by an exaggerated CD4 Th2 response. We have shown that OVA coupled with cholera toxin (CT) when administered intranasally into mice recapitulate the hallmarks of asthma. In vitro, CT ‐treated Dcs prime naïve T cells towards a Th2 response. We undertook a microarray approach to dissect the mechanism of CT‐ induced Th2 response. Our microarray data revealed upregulation of expression of vascular endothelial growth factor (VEGF) by CT in DCs. Recently, a novel role for VEGF as a mediator of Th2 immune responses has been reported. In accordance with our microarray data, CT induced secretion of VEGF in tissue and bone marrow DCs. Interestingly, we have found that allergens selectively induce VEGF expression in DCs despite their common ability to promote allergic diseases. Aspergillus fumigatus, the causative agent of allergic bronchopulmonary aspergillosis, induced VEGF production from DCs but house dust mite did not. We also found that VEGF secreted by DCs was critical for the differentiation of Th2 cells. We show that iNOS and NF‐kappa B enhance the production of VEGF from DCs, in contrast to inhibition by IL‐12. We also show the Th2‐ priming ability of DCs to be compromised in iNOS −/− mice. In summary, our study underscores the complexity of Th2 responses by highlighting a previously unknown but essential pathway via DC‐derived VEGF in response to specific stimuli.
Electronic structure calculations of fluorohistidine isomers (2014)

Presented at the 248th National Meeting of the American Chemical Society (ACS) held in San Francisco, California on August 11, 2014.
Polyclonal activation of the murine immune system by an antibody to IgD. I. Increase in cell size and DNA synthesis. (1982)

Abstract Although anti-immunoglobulin antibodies induce B lymphocyte proliferation in some in vitro culture systems, the stimulation of B cell proliferation by a ligand-B lymphocyte surface immunoglobulin interaction has not been established in vivo. We found that by 24 hr after the injection of adult BALB/c mice with 800 µg of an affinity-purified, isotype-specific goat antibody to mouse IgD (GaMδ) there was a substantial increase in size and DNA content of splenic B lymphocytes. Two days after GaMδ injection almost all splenic B cells had increased in size, and these cells exhibited a several fold increase in the rate of DNA synthesis. Although there was no increase in the size or extent of proliferation of T lymphocytes at this time, by 7 days after GaMδ injection both B and T lymphocytes exhibited considerable increases in size and rate of DNA synthesis, and a four to sixfold increase in spleen cell number was seen. In congenitally athymic (nu/nu) mice and mice tolerant to the injected anti-δ antibody only the early phase of B cell proliferation was seen. Thus, the interaction of a ligand with surface IgD appears to stimulate spleen cell proliferation in two phases; an early, T-independent, carrier-independent phase that involves B cells but not T cells, and a later T-dependent, carrier-dependent phase that involves both sets of lymphocytes. The injection of mice with heat-aggregated goat immunoglobulin or a monoclonal rat antibody to a nonimmunoglobulin B lymphocyte surface molecule, ThB, did not stimulate B cell proliferation. This suggests that the induction of B cell proliferation by anti-δ results from a specific signal generated by the binding to and cross-linking of surface IgD by ligand, rather than by the binding of ligand to any B cell surface molecule. These results indicate that the interaction of ligand with B cell surface immunoglobulin can have a physiologic role in the expansion of B cell clones that bind that ligand.
Solving Engineering Problems With Materials Science Forensics: Fragmented B83 Deployment Ring. (2020)

Abstract not provided.
Numerical classification of <i>Rhodococcus equi</i> and related actinomycetes (1982)

Eighty‐three strains received as Corynebacterium or Rhodococcus equi and marker cultures of Corynebacterium and Rhodococcus species were subjected to numerical phenetic analyses using 112 unit characters. The data were examined using the simple matching ( S SM ) and Jaccard ( S J ) coefficients and clustering was achieved using the average linkage algorithm. Cluster composition was not markedly affected by the coefficient used or by test error, estimated at 2.9%. Most of the strains received as R. (C.) equi formed a distinct and homogeneous cluster in the aggregate Rhodococcus taxon, the strains of which were sharply separated from marker cultures of C. pseudotuberculosis and C. renale. The taxon R. equi was redescribed and Nocardia calcarea Metcalf & Brown reduced to a subjective synonym of R. erythropolis (Gray & Thornton) Goodfellow & Alderson.
An effective synthesis of (.+-.)-(E)-2-amino-5-phosphono-3-pentenoic acid by palladium (II)-assisted migration of the double bond. (1990)

A new approach for the synthesis of ( )-()-2-amino-5-phosphono-3-pentenoic acid (-APPA) is described. The key intermediate, ()-5-acetoxy-3,4-dehydronorvaline derivative 8, was prepared by
Growth Factors for Corynebacterium diphtheriae Strain Dundee (1956)

Summary: Investigations were continued on the nature of the growth factor requirements of Corynebacterium diphtheriae gravis, strain Dundee. Hypoxanthine, or adenine + guanine, or adenine + xanthine, were found capable of replacing concentrates of the growth factor from liver and yeast. Nucleoside and nucleotide fractions, prepared from electrophoretically-purified ribonucleic acid, were unable to replace the free purine bases. A purine extract was obtained from an active fish-liver concentrate by copper precipitation. In this extract, a large amount of hypoxanthine and a smaller amount of xanthine were found by chromatography to be the major purine constituents; traces of adenine and guanine were also detected. Chromatographic fractionation and spectro-photometric examination of the fractions confirmed the presence of hypoxanthine and xanthine, whose concentrations were estimated. The purine extract supported less growth than the original fish-liver concentrates. Growth on the purine extract could be reproduced by a mixture of hypoxanthine and xanthine at an equivalent concentration.
Evidence for the heterolytic fission of H2 by cobalt cyanide complexes (1981)

Summary The relative intensities of the Co–H/D stretching vibrations in the precipitated products show that the reaction of H2 with [COII5]3–(L = CN–) in D2O produces equal amounts of [CoIIIL5H]3– and [CoIIIL5D]3– which, taken together with kinetic and electrochemical data, indicates that H2 reacts with a binuclear [CO2L10]6– ion by heterolytic fission.
Analysis of Wind Power Generation of Texas (2007)

Blue series: difference from 10 MW to 40 MW (measured minus predicted)
Long-term registration has improved the quality of hip replacement: A review of the Swedish THR Register comparing 160,000 cases (2000)

The Swedish Hip Register has defined the epidemiology of total hip replacement in Sweden. Most hip implants are fully cemented. Serious complications and rates of revision have declined significantly despite an increasing number of patients at risk. During the past 5 years, only 8-9% of hip replacements are revisions. Aseptic loosening with or without osteolysis is the major problem and constitutes 71% of the revisions, but the incidence had decreased three times during the past 15 years to less than 3% at 10 years. The effectiveness of the surgical technique is the most important factor for reducing the risk of revision because of aseptic loosening, but choice of implant is also important. In practice, total hip replacement in Sweden has improved, as judged by information from this Register about individualized patient risks, implant safety, and the greater efficacy of surgical and cementing techniques.
Regulation of nuclear receptor and cofactor expression in breast cancer cell lines (2003)

The results showed that not only is the expression profile of the NRs and cofactors cell line specific but also the regulation of NR expression. Thus the determinants of the ligand action (receptor and cofactor expression) varied considerably among different cell clones of the breast cancer cells. This suggested a gradient of NR-ligand sensitivities in the hormone-dependent breast cancers, which produces an additional challenge in developing novel ligands for hormone replacement therapy and breast cancer treatment.
Expression of the cloned bacteriophage phi X174 A* gene in Escherichia coli inhibits DNA replication and cell division (1985)

The A* gene of bacteriophage phi X174 has been cloned into the inducible expression vector pCQV2 under conditions allowing its lethal action to be controlled by the lambda cI857 repressor. Upon induction of expression, DNA synthesis in Escherichia coli carrying the recombinant plasmid is severely inhibited; however, these same cells permit beta-galactosidase induction at a rate similar to that observed in control cells at the inducing (for A*) temperature. Cells in which A* is expressed form filaments and produce more RecA protein, indicating at least a partial induction of the SOS response; however, there is no evidence of damage to the bacterial chromosome. It appears that the A* protein has as one function the inhibition of cell division and DNA replication but not transcription or protein synthesis during phage infection.
Effects of European Corn Borer (Lepidoptera: Pyralidae) Damage on Yields of Spring-Grown Potatoes1 (1983)

Journal Article Effects of European Corn Borer (Lepidoptera: Pyralidae) Damage on Yields of Spring-Grown Potatoes Get access G. G. Kennedy G. G. Kennedy Department of Entomology, North Carolina State University, Raleigh, North Carolina 27650 Search for other works by this author on: Oxford Academic PubMed Google Scholar Journal of Economic Entomology, Volume 76, Issue 2, 1 April 1983, Pages 316–322, https://doi.org/10.1093/jee/76.2.316 Published: 01 April 1983 Article history Received: 23 July 1982 Published: 01 April 1983
Molecular “Tuning” of Crystal Growth by Nacre-Associated Polypeptides (2005)

The formation and stabilization of the aragonite polymorph in the nacre layer of mollusks is an intriguing process, yet very little is known with regard to the participation of proteins in this process. Previously, we identified the 30 AA N-terminal mineral binding domains (AP7-N, AP24-N, n16-N) of three different nacre-specific proteins (AP7, AP24, n16). These three domains differ in primary sequence and induce morphological changes in CaCO3 crystals in vitro. Using AFM microscopy, we investigated the adsorption of AP7-N, AP24-N, and n16-N onto calcite dislocation hillocks. We observe that both AP7-N and AP24-N are multifunctional; they not only inhibit obtuse step advance but also induce rounded, amorphous-appearing deposits on hillock terraces. In contrast, n16-N pins corner sites at the junction of acute and obtuse steps and promote the emergence of a new set of steps approximately oriented along a line joining the obtuse−obtuse and the acute−acute corners. Random scrambling of the n16-N and AP7-N sequences resulted in substantially reduced mineral modification activities, indicating that the primary sequence of both polypeptides is crucial for correct recognition of surface features. These findings indicate that nacre proteins evolved specialized mineral interaction domains that either recognize different surface features (AP7-N, AP24-N versus n16-N), or recognize the same features, but with different binding and catalytic activities (AP24-N versus AP7-N). These functional differences may arise from the differences in primary and secondary structure specific to each N-terminal domain. Hypothetically, this molecular diversity would allow complementary and simultaneous protein control (“molecular tuning”) of different features of the crystal growth process.
Possible Evidence for Re-regulation of HPA Axis and Brain Reward Systems Over Time in Treatment in Prescription Opioid-Dependent Patients (2014)

These results suggest possible re-regulation of dysregulated hypothalamic-pituitary-adrenal axis and brain reward systems in prescription opioid-dependent patients over the drug-free period in residential treatment.