gebhart/patrepeval huggingface dataset:
Effect of Outflow Orientation on Heat Transfer and Pressure Drop in a Triangular Duct With an Array of Tangential Jets (2000)

Experiments are conducted to study the heat transfer and pressure drop characteristics in a triangular duct cooled by an array of tangential jets, simulating the leading-edge cooling circuit of a turbine blade. Coolant ejected from a high-pressure plenum through an array of orifices is aimed at the leading-edge apex and exits from the radial outlets. Three different outflow orientations, namely coincident with the entry flow, opposed to the entry flow, and both, are tested for various Reynolds numbers 12600⩽Re⩽42000. A transient liquid crystal technique is used to measure the detailed heat transfer coefficients on two walls forming the leading-edge apex. Flow rate across each jet hole and the crossflow development, which are closely related to the local heat transfer characteristics, are also measured. Results show that increasing Re increases the heat transfer on both walls. The outflow orientation affects significantly the local heat transfer characteristics through influencing the jet flow together with the crossflow in the triangular duct. The triangular duct with two openings is recommended since it has the highest wall-averaged heat transfer and the moderate loss coefficient among the three outflow orientations investigated. Correlations for wall-averaged Nusselt number and loss coefficient in the triangular duct have been developed by considering the Reynolds number for three different outflow orientations. [S0022-1481(00)01204-4]
Neurotrophic Factors and Parkinson’s Disease: The Emergence of a New Player? (2007)

The administration of neurotrophic factors is a potential approach to the therapy of neurodegenerative disorders such as Parkinson's disease. However, issues relating to compound delivery and potential side effects have limited the clinical application of this treatment strategy. The identification of CDNF and MANF, which constitute a new class of neurotrophic factors active against dopaminergic neurons, may provide new hope for therapeutic approaches to neurodegenerative disorders based on neurotrophic factors or downstream components of their signaling pathways.
OX40 Ligand and CD30 Ligand Are Expressed on Adult but Not Neonatal CD4+CD3− Inducer Cells: Evidence That IL-7 Signals Regulate CD30 Ligand but Not OX40 Ligand Expression (2005)

In this report, we have examined the expression of the T cell survival signals, OX40 ligand (OX40L) and CD30 ligand (CD30L) on CD4(+)CD3(-)CD11c(-)B220(-)IL-7Ralpha(+) inducer cells from birth to adulthood in mice. We found that adult but not neonatal inducer cells expressed high levels of OX40L and CD30L, whereas their expression of TNF-related activation-induced cytokine (TRANCE) and receptor activator of NF-kappaB (RANK) was comparable. The failure of neonatal inducer cells to express the ligands that rescue T cells helps to explain why exposure to Ag in neonatal life induces tolerance rather than immunity. The expression of OX40L and CD30L on inducer cells increased gradually in the first few weeks of life achieving essentially normal levels around the time mice were weaned. We found that IL-7 signaling through the common cytokine receptor gamma-chain was critical for the optimal expression of both TNF-related activation-induced cytokine and CD30L but not OX40L. Furthermore, glucocorticoids, which potently suppress T effector function, did not influence the expression of OX40L and CD30L in the presence of IL-7.
Color-tunable Gd-Zn-Cu-In-S/ZnS quantum dots for dual modality magnetic resonance and fluorescence imaging (2014)

Inorganic nanoparticles have been introduced into biological systems as useful probes for <i>in vitro</i> diagnosis and <i>in vivo</i> imaging, due to their relatively small size and exceptional physical and chemical properties. A new kind of color tunable Gd-Zn-Cu-In-S/ZnS (GZCIS/ZnS) quantum dots (QDs) with stable crystal structure was successfully synthesized and utilized for magnetic resonance (MR) and fluorescence dual modality imaging. This strategy allows successful fabrication of GZCIS/ZnS QDs by incorporating Gd into ZCIS/ZnS QDs to achieve great MR enhancement without compromising the fluorescence properties of the initial ZCIS/ZnS QDs. The as-prepared GZCIS/ZnS QDs show high <i>T</i><sub>1</sub> MR contrast as well as "color-tunable" photoluminescence (PL) in the range of 550-725 nm by adjusting the Zn/Cu feeding ratio with high PL quantum yield (QY). The GZCIS/ZnS QDs were transferred into water <i>via</i> a bovine serum albumin (BSA) coating strategy. The resulting Cd-free GZCIS/ZnS QDs reveal negligible cytotoxicity on both HeLa and A549 cells. Both fluorescence and MR imaging studies were successfully performed <i>in vitro</i> and <i>in vivo</i>. The results demonstrated that GZCIS/ZnS QDs could be a dual-modal contrast agent to simultaneously produce strong MR contrast enhancement as well as fluorescence emission for <i>in vivo</i> imaging.
Diffraction characteristics of superimposed holographic gratings in planar optical waveguides (1992)

A coupled-mode analysis of superimposed holographic transmission gratings in single-mode planar optical waveguides is presented. The diffraction characteristics are shown to be sensitive to the polarization of the incident wave, the angular separation of the output waves and the relative index modulation between the gratings. The coupling between gratings affects the diffraction efficiencies and decreases the angular and wavelength selectivities. Nevertheless, good channel separation and high fanout can be obtained together.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Scattering of Solitary Waves from Interfaces in Granular Media (2005)

The scattering of nonlinear solitary waves from an interface is numerically studied in detail. The interface is created by joining two one-dimensional chains of spherical beads of different radii (masses). Beads are assumed to be in Hertzian contact, without static precompression, and to have identical mechanical properties. In addition to previous findings, it is observed that in both cases, when a solitary wave travels from the light to the heavy system and vice versa, secondary multipulse structures are generated at the interface, being backscattered and forward scattered, respectively.
Sleep in Zebrafish (2006)

Zebrafish (Danio rerio), a small prolific rapidly-developing diurnal vertebrate, shows behavioral, physiological, and pharmacological characteristics of mammalian sleep. Zebrafish brain has well-developed neuronal structures and neurochemical systems that are known to be necessary and sufficient for sleep regulation in other vertebrate species. Rich behavioral repertoire in zebrafish permits investigation of the effects of sleep and sleep deprivation on cognitive functions and performance. Sensitivity of this fish to hypnotic agents helps in designing high throughput screens for new hypnotic medications, evaluation of their efficacy, and potential side effects. The optical transparency of larval zebrafish and intracellular fluorescent markers of calcium responses available make it possible to visualize neuronal activity with single cell resolution in a behaving fish. Given the accumulated experience in conducting large-scale genetic screens in zebrafish, multiple available mutant phenotypes, and advanced genetic and physical maps of this vertebrate, zebrafish is an excellent model for studying the enigmatic basic sleep function and mechanisms of sleep regulation.
Phase-stepping interferometry with laser diodes: effect of changes in laser power with output wavelength (1989)

Get PDF Email Share Share with Facebook Tweet This Post on reddit Share with LinkedIn Add to CiteULike Add to Mendeley Add to BibSonomy Get Citation Copy Citation Text P. Hariharan, "Phase-stepping interferometry with laser diodes: effect of changes in laser power with output wavelength," Appl. Opt. 28, 27-29 (1989) Export Citation BibTex Endnote (RIS) HTML Plain Text Citation alert Save article
The effects of nitric oxide on <i>Staphylococcus aureus</i> biofilm growth and its implications in chronic rhinosinusitis (2011)

S. aureus biofilm formation varies across exposure to different NO levels, with antibiofilm effects at higher concentrations, and enhanced biofilm formation at lower or subphysiologic concentrations. These results coincide with the often dualistic function of NO, and have implications in its future use in the treatment of CRS.
Gender Differences in School-based Violence Among South Korean Adolescents (2012)

Chang, Mi-hye.July, 2012.Gender differences in school-based violence among South Korean adolescents,Article,SeoulKorea Women’s Development Institute,30
Cluster size convergence of the density matrix embedding theory and its dynamical cluster formulation: A study with an auxiliary-field quantum Monte Carlo solver (2017)

We investigate the cluster size convergence of the energy and observables using two forms of density matrix embedding theory (DMET): the original cluster form (CDMET) and a new formulation motivated by the dynamical cluster approximation (DCA-DMET). Both methods are applied to the half-filled one- and two-dimensional Hubbard models using a sign-problem free auxiliary-field quantum Monte Carlo impurity solver, which allows for the treatment of large impurity clusters of up to 100 sites. While CDMET is more accurate at smaller impurity cluster sizes, DCA-DMET exhibits faster asymptotic convergence towards the thermodynamic limit. We use our two formulations to produce new accurate estimates for the energy and local moment of the two-dimensional Hubbard model for $U/t=2,4,6$. These results compare favorably with the best data available in the literature, and help resolve earlier uncertainties in the moment for $U/t=2$.
Bacterial spore components which enhance the bacteriostatic effectiveness of S-nitrosothiol (1981)

Spore components exuded into the medium during outgrowth of Bacillus cereus T enhanced the bacteriostatic effectiveness of S-nitrosomercaptoethanol, an inhibitor which prevents outgrowth at low concentrations and germination at higher concentrations. The enhancement effect was slight with respect to outgrowth, but dramatic with respect to germination, in that the inhibitory effectiveness of nitrosothiols toward germination inhibition was enhanced by as much as 33-fold when nitrosothiols was in the presence of the exuded spore component. Exudate activity was freely dialyzable and was not measurably affected by a broad-spectrum protease (proteinase K), by autoclaving at 121 degrees C, or by freezing and thawing. Sephadex G-25 chromatography of the exudate indicated that two active species were present, a major component with a molecular weight of less than 1,000 and a minor component with a molecular weight of more than 5,000.
Clinical Cancer Genetics: Risk Counseling and Management (1998)

Clinical Cancer Genetics and Risk Counseling. Hereditary and Acquired Risks for Cancer. Cancer as a Genetic Disorder. The Common Hereditary Cancers. Other Cancer Predisposition Syndromes. Quantitative Methods in Cancer Risk Assessment. Laboratory Methods of Cancer Genetic Testing. Genetic Testing in the Management of Patients with Cancer. Reproductive Counseling for Cancer Patients and Families. Psychological, Ethical, and Legal Issues of Cancer Risk Counseling. Glossary. Appendices. Index.
Martingale limit theory (1975)

A central limit theorem for martingales was considered as early as 1935» when Paul Levy established several results. However, it is only since the 1960's that the field has received much attention, and some of the most important work was published by Erown [9] in 1971. In this dissertation we take a critical look at the present situation of martingale central limit theory. We change the form of the classical central limit problem and show that in this new form it has a solution under more general conditions. This leads us to analogous results for reverse martingales, and to a new form of the law of the iterated logarithm.
Conservation of salivary glycoprotein-interacting and human immunoglobulin G-cross-reactive domains of antigen I/II in oral streptococci (1994)

In this study we localized more precisely the salivary glycoprotein-interacting and the human immunoglobulin G (hIgG)-cross-reacting domains on the SR molecule, an antigen I/II-related protein from S. mutans serotype f. Mapping of the SR molecule with polypeptides expressed by subclones covering the entire molecule and with synthetic peptides demonstrates that the salivary glycoprotein-binding domain is located in the N-terminal alanine-rich repeats of the SR molecule. In order to investigate the degree of conservation of both regions in various oral streptococci, we tested the reactivity of 8 representative strains of the mutans group and 11 nonmutans oral Streptococcus strains (S. anginosus, S. milleri, S. constellatus, S. intermedius, S. mitis, S. sanguis, S. gordonii, S. salivarius, and S. mitis strains) with antipeptide antibodies in a whole-cell enzyme linked immunosorbent assay together with colony hybridization analysis using DNA probes designed to map these two regions. All the mutans group strains except S. rattus and the 11 nonmutans streptococcal strains showed a high conservation of the C-terminal part of the SR molecule, especially the hIgG-cross-reacting domain, and less homology for the N-terminal salivary glycoprotein-binding region. Almost all of the sera from patients with rheumatic disease reacted strongly with SR from S. mutans serotype f, P1 from S. mutans serotype c, and four peptides located in the hIgG-cross-reacting region and not with peptides located at the C and N termini and in the proline-rich repeats. These results confirm that epitopes located within this region are immunogenic in humans and could lead to the synthesis of natural anti-IgG antibodies.
Medically Important Solar Ultraviolet (1988)

Results from a 6-year study of solar ultraviolet A (UVA) radiation measurements at the equatorial location of Penang (5 degrees N) are presented. On clear days, the diurnal flux reaches a very high dosage of about 3.0 x 10(-2) KWHM-2 around midday. The average daily total flux is in the range of 1.6 x 10(-1) KWHM-2 and does not change much seasonally. The high 83% cloud cover only reduces the incoming flux to about half. The radiation flux represents a lower limit of the incident UVA radiation applicable to much of the equatorial/tropical region.
Active control of nonlinear pressure oscillations in combustion chambers (1992)

A theoretical analysis of active control of nonlinear acoustic instabilities in combustion chambers is developed in this article. The formulation starts with a generalized wave equation that describes the dynamic behavior of second-order nonlinear oscillations with distributed feedback actions. Control inputs are provided by the burning of the injected seconday fuel in the chamber, with its instantaneous mass flow rate modulated by a proportionalplus-integral (PI) controller located between the pressure sensor and the fuel injection mechanism. Various nonlinear stability characteristics, including the existence and stability of limit cycles, are studied analytically using the method of time averaging. In addition, an optimization procedure is developed for selecting controller gains. Nomenclature Anij = parameters associated with nonlinear acoustic coupling a = speed of sound in mixture Bnij = parameters associated with nonlinear acoustic coupling b = spatial distribution of burning of control fuel, Eq. (5b), Cv - constant-volume specific heat for two-phase mixture c = amplification factor of sensor output Dni = linear parameters, Eq. (11) Eni = linear parameters, Eq. (11) e - error signal between desired response and actual measurement
The Remediation of the Student At-Risk for Failure (1982)

Journal of Developmental & Behavioral Pediatrics: December 1982 - Volume 3 - Issue 4 - p 257
Recovery of Valuable Chlorosilane Intermediates by a Novel Waste Conversion Process (2002)

From 1994 to 2001, Dow Corning studied a waste recycling process to recover direct process residues (DPR) resulting from the production of silicone precursors. Over the course of eight years, Dow Corning constructed and operated a pilot plant, a small scale commercial plant, and a full scale plant. The process reacts DPR with hydrogen and chlorosilane monomers at high temperature and high pressure. The process converted 85% of the DPR to valuable chlorosilane monomers such as dimethyldichlorosilane and methyldichlorosilane. When feeding methyltrichlorosilane, the process converted 30% of the MeSiCl3 to other monomers. Alternate co-feed monomers were tested. By converting waste DPR to valuable intermediates, the technology significantly reduces waste from the basic silicones manufacturing process.
Characterization and Analysis of Damage Progression in Non-Traditional Composite Laminates With Circular Holes (2006)

Carbon Fiber / Epoxy Laminates are increasingly being used in the primary structure of aircraft. To make effective use these materials, it is necessary to consider the ability of a laminate to resist damage, as well as material strength and stiffness. A possible means for improving damage tolerance is the use of non-traditional composite laminates, in which the longitudinal 0 plies are replaced with 5 or 10 plies. The main objectives of this collaborative Georgia Tech / Boeing research was the characterization of these non-traditional laminates, and the determination of appropriate lamina-level analytical techniques that are capable of predicting the changes caused by the use of slightly off-axis longitudinal plies. A quasi-isotropic [45/90/-45/theta/45/90/-45/-theta]s and hard [45/theta/-45/theta/90/45]s lay-up, where theta =0,5 or 10, were tested in open hole tension, filled hole tension, open hole compression, single shear bearing, and unnotched tension. These coupon level tests illustrated the effects of lay-up, notch constraint, and load type on traditional and non-traditional laminates. Die penetrant enhanced in-situ radiography was performed to determine the extent of damage suppression. The use of non-traditional laminates was found to reduce longitudinal ply cracking and delamination, with significant effect on the stress distribution around the notch. The use of non-traditional laminates also resulted in a 15%-20% improvement in bearing strength of the traditional laminates. Several predictive techniques were implemented to evaluate their ability to predict the effect of slight changes in ply orientations. A progressive damage model was written to compare Tsai-Wu, Hashin, and Maximum Stress unnotched strength criterion. Additionally, several semi-empirical failure theories for notched strength prediction were compared with linear and bi-linear cohesive zone models to determine applicability to non-traditional laminates.
Long-term safety and efficacy of amisulpride in subchronic or chronic schizophrenia (2000)

Amisulpride is an atypical antipsychotic with selective affinity for dopamine D2/3 receptors. In this long-term, open, randomised, multicentre trial, patients with chronic or subchronic schizophrenia received amisulpride (n =370) or haloperidol (n = 118) for 12 months. Dosage regimens were flexible (amisulpride 200-800 mg/day, haloperidol 5-20 mg/day). Improvement in mean Brief Psychiatric Rating Scale total score was significantly greater for amisulpride than haloperidol (17.0 versus 12.8, P = 0.01). Positive symptoms (Positive and Negative Syndrome Scale [PANSS] positive) improved in a similar way in each group but amisulpride caused a significantly better improvement in negative symptoms (PANSS negative) (7.1 versus 3.7, P < 0.0001). Improvements in Global Assessment of Functioning (GAF) and Quality of Life Scale (QLS) scores were also significantly greater in the amisulpride group (GAF -20.1 versus -13.6, P = 0.001; QLS -0.64 versus -0.30, P = 0.02). Adverse events were mainly psychiatric in nature, and occurred with similar frequency in each group (amisulpride 254/370, 69%; haloperidol 82/118, 70%). Extrapyramidal symptoms were more frequent for haloperidol (48/118, 41% versus 96/370, 26% for amisulpride), leading to a greater requirement for antiparkinsonian medication (haloperidol 66/118, 56% versus amisulpride 118/370, 32%). Haloperidol significantly aggravated parkinsonism, akathisia and involuntary movement compared to amisulpride. The overall incidence of endocrine events was comparable between groups (4% for amisulpride, 3% for haloperidol). Maintenance of efficacy was comparable in both treatment groups; 59% of amisulpride patients and 55% of haloperidol patients improved after 1 month of therapy remained improved throughout the study period. Amisulpride is effective following flexible long-term administration and significantly improves social functioning and quality of life.
Stereospecific Friedel-Crafts reaction. Alkylation of benzene with .gamma.-valerolactone (1967)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTStereospecific Friedel-Crafts reaction. Alkylation of benzene with .gamma.-valerolactoneJohn I. Brauman and Alexander J. PandellCite this: J. Am. Chem. Soc. 1967, 89, 21, 5421–5424Publication Date (Print):October 1, 1967Publication History Published online1 May 2002Published inissue 1 October 1967https://pubs.acs.org/doi/10.1021/ja00997a022https://doi.org/10.1021/ja00997a022research-articleACS PublicationsRequest reuse permissionsArticle Views388Altmetric-Citations24LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Mental health. -letter- (2007)

The author notes that the concept and use of problem solving therapy (PST) relating to life events should be introduced early in life (eg. at school level) so that young adults can face life?s challenges with greater confidence. (non-author abstract)