gebhart/patrepeval huggingface dataset:
The Human SNF5/INI1 Protein Facilitates the Function of the Growth Arrest and DNA Damage-inducible Protein (GADD34) and Modulates GADD34-bound Protein Phosphatase-1 Activity (2002)

The growth arrest and DNA damage-inducible protein (GADD34) mediates growth arrest and apoptosis in response to DNA damage, negative growth signals, and protein malfolding. GADD34 binds to protein phosphatase-1 (PP1) and can attenuate translational elongation of key transcriptional factors through dephosphorylation of eukaryotic initiation factor-2alpha. We reported previously that the human trithorax leukemia fusion protein (HRX) can bind to GADD34 and abrogate GADD34-mediated apoptosis in response to UV irradiation. We found that hSNF5/INI1, a component of the hSWI/SNF chromatin remodeling complex, also binds to GADD34 and can coexist with GADD34 and HRX fusion proteins as a trimolecular complexes in vivo. In the present report, we demonstrate that hSNF5/INI1 binds to GADD34 in part through the PP1 docking site within a domain homologous to herpes simplex virus-1 ICP34.5. We found that hSNF5/INI1 can bind PP1 independently and weakly stimulate its phosphatase activity in solution and in complex with GADD34. hSNF5/INI1 and PP1 do not compete for binding to GADD34 but rather form a stable heterotrimeric complex with GADD34. We also show that Epstein-Barr nuclear protein 2, which binds hSNF5/INI1, can disrupt hSNF5/INI1 binding to GADD34 and partially reverse the GADD34-mediated growth suppression function in Ha-ras expressing HIH-3T3 (3T3-ras) cells. These results implicate hSNF5/INI1 in the function of GADD34 and suggest that hSNF5/INI1 may regulate PP1 activity in vivo.
An overview of radiation safety regulatory recommendations and requirements (1999)

This article reviews the formal basis of radiation protection programs. It also reviews the application of these programs in the cardiac catheterization laboratory. Radiation protection rules are based on epidemiology, radiobiology, and radiation physics. Applicable scientific results are periodically reviewed by committees reporting to the United States National Academy of Science and to the United Nations. National and international expert committees convert science to recommendations. The legislative process enacts enforceable regulations. These regulations need to be interpreted in relation to the actual risks experienced by the fluoroscopist. Cathet. Cardiovasc. Intervent. 47:469–474, 1999. © 1999 Wiley-Liss, Inc.
La vulnerabilite et la mesure de la pauvrete dans la politique publique (2002)

The paper presents the main approaches, and tools to measuring poverty, and vulnerability. This involves among other things, the important issues of the setting of poverty lines, of the statistical use of surveys, of the empirical measurement of living standards, and of making poverty comparisons. The computation of aggregate poverty indices, and the use of poverty dominance testing are also described. Throughout, implications for the understanding of the effects of public policy are highlighted, in particular, those related to the design of safety nets.
Mitochondrial localization of a NADR-dependent isocitrate dehydrogenase isoenzyme by using the green fluorescent protein as a marker (1998)

In this work, we describe the isolation of a new cDNA encoding an NADP-dependent isocitrate dehydrogenase (ICDH). The nucleotide sequence in its 5' region gives a deduced amino acid sequence indicative of a targeting peptide. However, even if this cDNA clearly encodes a noncytosolic ICDH, it is not possible to say from the targeting peptide sequence to which subcellular compartment the protein is addressed. To respond to this question, we have transformed tobacco plants with a construct containing the entire targeting signal-encoding sequence in front of a modified green fluorescent protein (GFP) gene. This construct was placed under the control of the cauliflower mosaic virus 35S promoter, and transgenic tobacco plants were regenerated. At the same time, and as a control, we also have transformed tobacco plants with the same construct but lacking the nucleotide sequence corresponding to the ICDH-targeting peptide, in which the GFP is retained in the cytoplasm. By optical and confocal microscopy of leaf epiderm and Western blot analyses, we show that the putative-targeting sequence encoded by the cDNA addresses the GFP exclusively into the mitochondria of plant cells. Therefore, we conclude that this cDNA encodes a mitochondrial ICDH.
Thermal Measurement of Harsh Environments Using Indirect Acoustic Pyrometry (2007)

The inversion of a composite governing equation for the estimation of a boundary heat flux from ultrasonic pulse data is presented. The time of flight of the ultrasonic pulse is temperature dependent and can be used to predict the boundary heat flux. Sensitivities of the approach are examined, results from fabricated data are presented, and example solutions are provided with actual ultrasonic temperature measurement data. The results indicate that compared to the canonical inverse heat conduction problem, the additional step of resolving the time-of-flight data to temperature degrades the sensitivities. Nevertheless, sampling the entire temperature distribution and enhances the results. This method of using ultrasonic pulses to remotely determine heat fluxes is comparable in terms of accuracy to more common heat flux estimation methods.
Load forecasting and its calibration method considering the influence of temperature (2008)

A calibration method for the medium/long-term load forecasting is presented. Firstly, a calibration model is built up, based on the regular pattern that the same trend is basically shared by the peak load and the maximum temperature. Secondly, a calibration method is presented. The first step is to correct the historical annual peak load and obtain the load which has no relations with the temperature. Then, forecast the peak load of the horizontal year by traditional way, regarding the corrected load obtained above as the historical data. At last, calibrate the result of forecasting according to the maximum temperature of the horizontal year and the final result is obtained. Finally, a practical case indicated that the model and method proposed by this paper can take the affection of temperature on the peak load into account in forecasting and calibrating, resulting in higher precision of load forecasting. The method has been successfully applied in an urban distribution network planning project.
Design concept to reduce fuel NO<sub><i>X</i></sub> in catalytic combustion of gasified biomass (2003)

Abstract A reactor concept was studied to reduce the fuel NO x at conditions relevant to catalytic combustion of gasified biomass containing ammonia. A hybrid reactor is modeled with passive and active channels, where only part of the fuel is combusted catalytically in the active channels. The completion of the reactions is carried out in the subsequent homogeneous zone. The air–fuel ratio is found to be the most important parameter for the NO x emission level. When the primary zone is operated fuel‐lean, no favorable conditions are established for selective noncatalytic reduction reactions in the homogeneous zone, and the fuel nitrogen is largely oxidized to NO. However, if the air supply to the monolith is staged rich‐lean, a 95% reduction in NO is possible. The NO reduction is facilitated by the remaining fuel components, CO and H 2 .
hTERT regulation by NF-κB and c-myc in irradiated HER2-positive breast cancer cells (2011)

The present study suggests that following irradiation, HER2 receptor activates hTERT/telomerase, increasing the breast cancer cells' survival potential, through sequential induction of transcription factors NF-κΒ and c-myc.
Estimation of Inertial Parameters of Manipulator Loads and Links (1986)

The inertial parameters of manipulator rigid-body loads and links have been automatically estimated as a result of gen eral movement. The Newton-Euler equations have been recast to relate linearly the measured joint forces or torques via acceleration-dependent coefficients to the inertial parame ters, which have then been estimated by least squares. Load estimation was implemented on a PUMA 600 robot equipped with an R TI FS-B wrist force-torque sensor and on the MIT Serial Link Direct Drive Arm equipped with a Barry Wright Company Astek wrist force-torque sensor. Good estimates were obtained for load mass and center of mass, and the forces and torques due to movement of the load could be pre dicted accurately. The load moments of inertia were more difficult to estimate. Link estimation was implemented on the MIT Serial Link Direct Drive Arm. A good match was ob tained between joint torques predicted from the estimated parameters and the joint torques estimated from motor cur rents. The match actually proved superior to predicted torques based on link inertial parameters derived by CAD modeling. Restrictions on the identifiability of link inertial parameters due to restricted sensing and movement near the base have been addressed. Implications of estimation accu racy for manipulator dynamics and control have been consid ered.
Automated Data Validation Framework for Data Quality in Big Data Migration Projects (2014)

The process of moving vast amount of data from one place to another is called big data migration. Huge volume of data is extracted, transformed, structured and loaded from legacy data base into a newer structure in the process which leads to data corruption. Data validation testing is essential after data migration process over to ensure data quality. To perform efficient data migration process, source data are mapped to new system which handles all the data formats. It is important when upgrade and relocation of existing systems. Businesses are creating significant data management challenges by increasing volumes of data. They should be able to access and organize volumes of data stored in a variety formats. Compare to manual process, automate data validation improve data quality in less time and cost with good quality. This paper emphasis on proposing model to do automatic quality checks for huge volume of data migrations.
Noise and Vibration Reduction on the Single Axis Adaptive Damping Controls (2013)

Reducing or eliminating seat noise and vibration are the main objectives of a semi-active damping system implemented in a commercial vehicle seat. The system must be developed such that control forces minimize seat motion. Abrupt motion with semi-active damping systems is typically called ‘dynamic jerk.’ Semi-active damping in a seat application places the control forces close to the seat occupant so there is less ‘filtering’ to protect the human from feeling dynamic jerk. Whereas in an automotive suspension there might be more tolerance for dynamic jerk because the comparatively heavy vehicle body acts to filter some of the dynamic jerk and the interaction of the tire and road input may also mask it. In this research, dynamic jerk has been addressed and studied for the advanced SEAT application. The seat has been tested with varying sine inputs at specific amplitudes. The response of the semi-active damping seat system has been analyzed to characterize dynamic jerk and a control algorithm has been developed to minimize this undesirable response. The conclusion is that dynamic jerk is dependent on the damper’s physical properties as well as the system’s sensors. A Design of Experiments statistical study was carried out to determine what are the most influencing factors. Limiting the range of damping force reduces the control authority; however, allowing full damping force may trigger dynamic jerk. Identifying the dynamic jerk plays an important role in order to have the indication of the properly tuned system. In this research, the identification strategy of the dynamic jerk is studied and developed.
Health Teaching For People With Disabilities (1995)

The authors inform nurses about their responsibility under the Americans with Disabilities Act to ensure equal access to health services and health education. This article is divided into two parts: (1) The Americans with Disabilities Act (ADA) is presented particularly in relation to health teaching. (2) Selected disabilities and helpful tips for positive interaction are discussed.
Processing methods for making porous bioactive glass‐based scaffolds—A state‐of‐the‐art review (2019)

Abstract Bioactive glasses exhibit the unique ability of bone bonding, thus creating a stable interface by stimulating bone cells toward mechanisms of regeneration and self‐repair activated by ionic dissolution products. Therefore, 3D glass‐derived scaffolds can be considered ideal porous templates to be used in bone tissue engineering strategies and regenerative medicine. This review provides a comprehensive overview of all technological aspects relevant to the fabrication of bioactive glass scaffolds, including the fundamentals of materials processing, a summary of the conventional porogen, and template‐based methods and of recent additive manufacturing technologies, which are promising for large‐scale production of highly reproducible and reliable implants suitable for a wide range of clinical applications.
Introduction (2004)

The Common Agricultural Policy (CAP) has always been of central importance to the functioning of the European Union (EU). This is so whether it is viewed from a political, economic, administrative, or legal perspective. This book provides an informed and engaging guide to the development of agricultural policy within the EU over time. The book's temporal perspective is most helpfully complemented by a thematic view of agricultural policy. The two pillars of the CAP are elaborated, with discussion of specific legal issues that have arisen. The discussion then moves beyond the two pillars to embrace concerns about food quality and safety. It is a further strength of this work that it places the CAP within the broader international frame, dealing specifically with the World Trade Organization and the pressures generated by enlargement of the EU towards the East.
The Investigation Of Motor Cooling Performance (2008)

This study experimentally and numerically investigates motor cooling performance. The motor consists of a centrifugal fan, two axial fans, a shaft, a stator, a rotor and a heat exchanger with 637 cooling tubes. The pressure rise-flow rate (P-Q) performance curves of the cooling fans at 1800 rpm are tested using a test apparatus complying with the Chinese National Standard (CNS) 2726. Compared with the experimental measurements, the numerical analysis results show that the P-Q performance curves of the axial fan and centrifugal fan can be estimated within about 2% and 6%, respectively. By using the simplified model, setting up the heat exchanger and stator as porous media, the flow field in the motor is calculated. By using the results of the flow field near the rotor and stator, and subjecting the heat generation rate as a boundary condition, the temperature distributions of the stator and rotor are also calculated. The simulation results show that the calculated temperature of the stator winding near the axial fans is lower by about 5% than the measured value, and the calculated temperature of the stator core located at the center of the stator is about 1% higher than the measured value. Besides, discussion is made to improve the motor cooling performance.
Automatic generation of test purposes for testing distributed systems (2003)

Abstract. In this paper, we present an algorithm for generating test purpose de-scriptions in form of MSC’s from a given labeled event structure that represents the behavior of a system of asynchronously communicating extended finite state machines. The labeled event structure is a non-interleaving behavior model describing the behavior of a system in terms of the partial ordering of events. 1
Small-angle scattering studies of macromolecular solutions (2007)

In recent years, major progress has been achieved in developing novel approaches to interpret small-angle scattering data from solutions of biological macromolecules in terms of three-dimensional models. These advanced methods include: ab initio low-resolution shape and domain structure determination; modelling of quaternary structure by rigid-body refinement; simultaneous analysis of multiple scattering patterns, e.g. from contrast variation in neutron scattering to study multicomponent complexes; validation of high-resolution models; and addition of missing loops and domains. The new techniques will be presented and practical applications of the methods are illustrated by recent examples. The use of additional information from other methods, joint applications of X-ray and neutron scattering, and the possibilities for assessing and validating the models constructed based on small-angle scattering data will be discussed.
A cytokinetic approach to determine the range of O<sub>2</sub>‐dependence of pyrimidine(deoxy)nucleotide biosynthesis relevant for cell proliferation (1992)

In vitro cultured Ehrlich ascites tumour (EAT) cells were used because of the ease of their manipulation under different levels of hypoxia. They were used to clarify further the complex mechanism of oxygen-dependent cell proliferation. On reducing the oxygen concentration from 20% to lower levels (1-7%) an increase in the length of the population doubling time with concomitant reductions in protein, RNA and DNA content of cultures were observed. The incorporation of [14C]HCO3- into the RNA fraction of cells by de novo biosynthesis of uridine monophosphate (UMP) was reduced proportionally to the microenvironmental O2 tension. Uptake of this labelled precursor by cells in the presence of N-phosphonoacetyl-L-aspartate was found to be similarly inhibited. To correlate the reduction of cell growth under hypoxia with the functional pyrimidine supply, hypoxic cells were cultured in the presence of a balanced mixture of deoxynucleosides and/or uridine (100 microM deoxycytidine, 10 microM deoxyadenosine, 10 microM deoxyguanosine, 100 microM uridine). Above 3% O2 in the protective atmosphere, no improvement of growth parameters by the exogenous pyrimidinenucleotide precursors was obtained, whereas these compounds had a positive influence below this level. The increase in cell number was raised to about 60% of that of control cultures (20% O2) irrespective of the oxygen tension. In addition, when above 3% O2 the incorporation of HCO3- into RNA was comparable to that of controls, indicating that the pyrimidine de novo pathway is not a limiting factor in RNA biosynthesis. In conclusion, whereas at suboptimal O2 levels (5-7%) no correlation between pyrimidine metabolism and reduction of proliferation rate appears to exist, at low O2 concentrations (less than 3%) the rate of orotate/UMP production seems to be an important factor in the growth cessation of EAT cells; at critical O2 tensions (less than 1%) the lack of pyrimidine-deoxynucleosides substantially reduces cell cycle progression.
Gas Chromatography Analysis of Gaseous Hydrocarbons by Gas-Liquid Partition Chromatography (1956)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXT Gas Chromatography Analysis of Gaseous Hydrocarbons by Gas-Liquid Partition ChromatographyE. M. Fredericks and F. R. BrooksCite this: Anal. Chem. 1956, 28, 3, 297–303Publication Date (Print):March 1, 1956Publication History Published online1 May 2002Published inissue 1 March 1956https://pubs.acs.org/doi/10.1021/ac60111a003https://doi.org/10.1021/ac60111a003research-articleACS PublicationsRequest reuse permissionsArticle Views299Altmetric-Citations57LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Competitive hydrogen production and emission through the photochemistry of mixed-metal bimetallic complexes (1990)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCompetitive hydrogen production and emission through the photochemistry of mixed-metal bimetallic complexesD. Brent MacQueen and John D. PetersenCite this: Inorg. Chem. 1990, 29, 12, 2313–2320Publication Date (Print):June 1, 1990Publication History Published online1 May 2002Published inissue 1 June 1990https://pubs.acs.org/doi/10.1021/ic00337a025https://doi.org/10.1021/ic00337a025research-articleACS PublicationsRequest reuse permissionsArticle Views269Altmetric-Citations38LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
High Visibility Time-Energy Entangled Photons from a Silicon Nanophotonic Chip (2016)

Advances in quantum photonics have shown that chip-scale quantum devices are translating from the realm of basic research to applied technologies. Recent developments in integrated photonic circuits and single photon detectors indicate that the bottleneck for fidelity in quantum photonic processes will ultimately lie with the photon sources. We present and demonstrate a silicon nanophotonic chip capable of emitting telecommunication band photon pairs that exhibit the highest raw degree of time-energy entanglement from a micro/nanoscale source, to date. Biphotons are generated through cavity-enhanced spontaneous four-wave mixing (SFWM) in a high-Q silicon microdisk resonator, wherein the nature of the triply resonant generation process leads to a dramatic Purcell enhancement, resulting in highly efficient pair creation rates as well as extreme suppression of the photon noise background. The combination of the excellent photon source and a new phase locking technique allow for the observation of a nearly perfect coincidence visibility of (96.6 ± 1.1)%, without any background subtraction, at a large pair generation rate of (4.40 ± 0.07) × 105 pairs/s.
Microwave Remote Sensing, Active and Passive (1982)

EN BIBLIOTECA: V.1: MICROWAVE REMOTE SENSING FUNDAMENTALS AND RADIOMETRY. V.2: RADAR REMOTE SENSING AND SURFACE SCATTERING AND EMISSION THEORY