gebhart/patrepeval huggingface dataset:
Recent Developments in Pattern Recognition (1980)

Extensive research and development has taken place over the last twenty years in the areas of pattern recognition. Areas to which these disciplines have been applied include business (e.g., character recognition), medicine (diagnosis, abnormality detection), automation (robot vision and automatic inspection), military intelligence, communications (data compression, speech recognition), and many others. This paper presents a very brief survey of recent developments in basic pattern recognition techniques.
Waveguide crossings by use of mutlimode tapered structures (2012)

A compact waveguide crossing constructed by three cascaded multimode tapers on each branch is numerically analyzed by finite difference time domain method, which possesses the size of 3920 nm×3920 nm, the insertion loss of 0.187 dB and the crosstalk of -47.58 dB at the wavelength of 1550 nm and broad transmission spectrum ranging from 1500 to 1600 nm.
LABORATORY EVALUATION OF CALCIUM CARBONATE PA,RTICLE SIZE SELECTION FOR DRILL-IN FLUIDS (2002)

The tehnological developments in horizontal, re-entry and multilateral wells require drilling and completion the rescrvoir sections of a well inducing as little damage as possible.The trends towards open hole completions places additional cmphasis on formation damage avoidance.One of the critical factors in avoiding formation damage str, 47-53 during drilling is obtaining surface bridging on the formation face with minimum indepth solids penetration.In case of overbalanced drilling, this can be done by optimizing the particle sizc distribution of calcium carbonate used as the bridging agent.The paper presents laboratory data from tests carried out on selected fluids which show the extent of the changes that occur in fluid filtration properties (spurt loss, PPT valuc and static filtration rate) when calcium carbonate with different PSD is used.The Permeability Plugging Tester was used to evaluate thc filtration and spurt loss of selected fluids.Thc ceramic disks with permeabilities 0,09 p3 (90 mD), 0,13 pml (130 mD) and 0,4 p2 (400 mD) were used as a filter medium.
Fast Start-up of a Combined-Cycle Power Plant: a Simulation Study with Modelica (2006)

The paper deals with the modelling and simulation of fast start-up transients of a combined-cycle power plant. The study is aimed at reducing the start-up time while keeping the life-time consumption of the more critically stressed components under control. The structure of the model, based on the ThermoPower library, and the main modelling assumptions are illustrated. Selected simulation results are included and discussed. 1
O transporte aéreo e o Código de Defesa do Consumidor (1998)

The article aims the analysis about the bifurcation of the air transport model under review, which is: international air transport and domestic air transport. So, the law applicable to the service relates to its execution and scope. About the international air service, it is now ruled by the Warsaw Convention, and domestic service by the Brazilian Aeronautical Code. Thus, the )rst part of this article is to present the legal relationship between consumers and airlines, conceptualizing their players and object. Later the author analyzes the application of con'ict and interpretation existing under such legislation from the perspective of the Brazilian Federal Constitution and the Consumer Protection Code.
A 10-bit 1-GS/s 2x-Interleaved Timing-Skew Calibration Free SAR ADC (2019)

This paper presents a 2x-interleaved 10-bit successive-approximation register (SAR) analog-to-digital converter (ADC) that performs 9.73 ENOB under 1-GS/s in 40nm with post-layout simulation. A bootstrapped switch circuit is proposed for 2x-interleaved structure using global master clock without any timing-skew calibration. In each channel, a sub-range SAR ADC sharing a common coarse SAR ADC with loop-unrolling technique is proposed to enhance speed. This ADC consumes 9.02mW with a figure of merit (FoM) of 10.6fJ/conv-step in post-layout simulation and only covers an area of 0.096mm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> .
Resolution of a Core Problem in Wound Rolls (1980)

Previous misunderstandings about the behavior of stresses in the vicinity of the core of wound rolls are resolved through the development of an explicit closed-form analytical solution for the radial and circumferential stresses which are generated during winding; the solution holds in the general case of variable winding tension. Asymptotic series are derived and then employed to compute profiles of stresses within the wound material for several cases of practical interest. A parametric analysis of the influence of core elasticity on structural integrity of the roll underscores the indispensable support provided by the core at the inner boundary of the roll. Results show that the circumferential stress in the vicinity of the core strongly depends on core stiffness. A relation that is derived between interlayer pressure and circumferential stress at the core boundary may be useful as a guide in core design and in preventing roll collapse.
Sensing of circulating cancer biomarkers with metal nanoparticles (2019)

The analysis of circulating cancer biomarkers, including cell-free and circulating tumor DNA, circulating tumor cells, microRNA and exosomes, holds promise in revolutionizing cancer diagnosis and prognosis using body fluid analysis, also known as liquid biopsy. To enable clinical application of these biomarkers, new analytical tools capable of detecting them in very low concentrations in complex sample matrixes are needed. Metal nanoparticles have emerged as extraordinary analytical scaffolds because of their unique optoelectronic properties and ease of functionalization. Hence, multiple analytical techniques have been developed based on these nanoparticles and their plasmonic properties. The aim of this review is to summarize and discuss the present development on the use of metal nanoparticles for the analysis of circulating cancer biomarkers. We examine how metal nanoparticles can be used as (1) analytical transducers in various sensing principles, such as aggregation induced colorimetric assays, plasmon resonance energy transfer, surface enhanced Raman spectroscopy, and refractive index sensing, and (2) signal amplification elements in surface plasmon resonance spectroscopy and electrochemical detection. We critically discuss the clinical relevance of each category of circulating biomarkers, followed by a thorough analysis of how these nanoparticle-based designs have overcome some of the main challenges that gold standard analytical techniques currently face, and what new directions the field may take in the future.
Very deep freeze (1995)

Ice‐core drillers at Russia's Vostok Station, atop the great ice sheet of East Antarctica, recently passed 3000 m—a depth at which the ice is about 300,000 years old. The depths of the Vostok ice core, when extracted, will reveal much older ages than the deep cores of the Greenland ice sheet, which were collected several years ago. Analysis of the Vostok cores over the past decade by Russian, U.S., and French scientists has yielded unique information about environmental and climatic changes over the last interglacial period.
Controlling im turbulenten Umfeld der Telekommunikationsbranche (2001)

Die Controlling - Zeitschrift für erfolgsorientierte Unternehmenssteuerung liefert Monat für Monat fundierte und anwendungsorientierte Fachbeiträge für das Management sowie das Finanz- und Rechnungswesen in Unternehmen. Klar gegliedert und strukturiert werden für alle Controlling-Bereiche die Faktoren für eine erfolgreiche Unternehmenssteuerung aufgezeigt.
Hepatitis C virus (HCV) core protein enhances the immunogenicity of a co‐delivered DNA vaccine encoding HCV structural antigens in mice (2006)

In the present study, recombinant HCV (hepatitis C virus) core proteins enhanced the immune response elicited by a co-delivered DNA vaccine encoding HCV core and envelope proteins. A mixture of the plasmid pIDKE2 and Co.173, a protein comprising the first 173 amino acids of HCV core, in particular induces a strong humoral response, including antibodies that recognized peptides representing hypervariable region I from different viral isolates. Moreover, positive lymphoproliferative responses against the HCV structural proteins, encoded by the plasmid, were detected after two doses with this mixture. When the HCV core protein used in the mixture with pIDKE2 was Co.120, a protein comprising the first 120 amino acids of the viral antigen, a strong humoral response and a positive lymphoproliferative response were also detected. The effectiveness of this formulation was tested in vivo by measuring the protection against infection with a recombinant vaccinia virus expressing HCV core protein. A 2 log reduction in vaccinia-virus titre was observed in mice immunized with the mixture of pIDKE2 and Co.120. Humoral and cellular immune responses elicited for the mixture of pIDKE2 with either Co.173 or Co.120 was stronger and more diverse than those generated by individual components. In conclusion, our results indicate that formulations comprising both DNA constructs and protein subunit vaccine candidates are able to elicit strong humoral and cellular immunity against several antigens. Particularly, HCV core protein might be used as a feasible vehicle/adjuvant for DNA vaccines.
Isolation from bovine spleen of a green heme protein with properties of myeloperoxidase. (1981)

A novel green heme protein from bovine spleen has been purified to apparent homogeneity. The visible spectrum, with unusually long wavelength absorptions due to alpha-, beta-, and gamma-porphyrin bands, the EPR g values of 6.81, 4.99, and 1.94, and the peroxidase activity are similar to those of myeloperoxidase (EC 1.11.1.7). The observed molecular mass of 57,000 daltons (established by gel permeation chromatography and sodium dodecyl sulfate-polyacrylamide gel electrophoresis studies) clearly distinguishes it from myeloperoxidase, as does the observed substrate specificity (e.g. oxidation of iodide but not ascorbate). Optical spectra of ferric and ferrous forms of the enzyme in the native state, complexed with ligands (CN-, CO, NO, N3-) and as the pyridine hemochromogens, are presented and compared to those of the corresponding derivatives of myeloperoxidase.
Deep Convolutional Neural Networks for Image Classification: A Comprehensive Review (2017)

Convolutional neural networks (CNNs) have been applied to visual tasks since the late 1980s. However, despite a few scattered applications, they were dormant until the mid-2000s when developments in computing power and the advent of large amounts of labeled data, supplemented by improved algorithms, contributed to their advancement and brought them to the forefront of a neural network renaissance that has seen rapid progression since 2012. In this review, which focuses on the application of CNNs to image classification tasks, we cover their development, from their predecessors up to recent state-of-the-art deep learning systems. Along the way, we analyze (1) their early successes, (2) their role in the deep learning renaissance, (3) selected symbolic works that have contributed to their recent popularity, and (4) several improvement attempts by reviewing contributions and challenges of over 300 publications. We also introduce some of their current trends and remaining challenges.
Clinical Trial of Epsilon-aminocaproic Acid in Severe Haemophilia (1965)

The main components of the fibrinolytic enzyme system are plasminogen, plasmin, activators, and inhibitors. Plasminogen, a naturally occurring plasma globulin, is converted by activators to plasmin, an enzyme which can digest many proteins, including fibrinogen and fibrin, prothrombin, factor V, and antihaemophilic globulin. Under physiological circumstances it is thought that natural inhibitors in the plasma restrict plasmin to digestion of fibrin, but in pathological fibrinolytic (hyperplasminaemic) states plasma proteins, including fibrinogen and antihaemophilic globulin, are digested. Activators of plasminogen include a plasma activator, trace quantities of which are probably responsible for physiological fibrinolytic activity, a urinary activator named urokinase, and activators of bacterial origin?for example, streptokinase. E.A.C.A., a potent competitive inhibitor of plasminogen activa tion (Alkjaersig et al., 1959), was first used in man by Sherry et al. (1959), who found it effective in inhibiting plasma fibrino lytic activity induced by a variety of plasminogen activators. The value of E.A.C.A. in the treatment of pathological fibrinolytic states has recently been reviewed by McNicol and Douglas (1964), who also discuss the pharmacology and toxicity of E.A.C.A. E.A.C.A., a synthetic amino-acid which closely resembles lysine in structure, is rapidly absorbed when taken by mouth. Peak plasma levels are found about two hours after a single oral dose. Urinary excretion is also rapid, the greater part of a single dose being recovered unchanged in the urine in 12 hours. The action of E.A.C.A. as an inhibitor of plasminogen activation is seen with plasma concentrations above 1 mg./100 ml. The first report of the use of E.A.C.A. in haemophilia was from McNicol et al. (1961a) who, during a study of the bene ficial effect on post-operative haemostasis of E.A.C.A. given to produce local inhibition of urokinase activity in the urinary tract, gave E.A.C.A. to a high-grade haemophiliac with haematuria. The haematuria ceased with E.A.C.A. administra tion, but at the same time the patient developed renal colic and was found subsequently to have permanent loss of function in one kidney, presumably because of ureteric blockage with unlysable clot. Steiger et al. (1962) and Barkhan (1964) have also reported successful control of haematuria in three patients and one patient respectively with haemophilia, without any adverse effects on renal function. Abe et al. (1962) and Reid et al. (1964) report favourably on the use of E.A.C.A. for other haemorrhagic complications in small numbers of haemophiliacs. On theoretical grounds there are reasons for considering that E.A.C.A. might have a beneficial systemic effect in the treatment of high-grade haemophilia, in addition to control of local
Repairs with visible light-curing denture base materials. (1991)

Visible light-curing interpenetrating networks are newly developed materials suitable for several dental applications. These materials have several advantages, including versatility and good physicomechanical properties, but also present some weaknesses, such as increased water sorption and poor adhesion to plastic teeth. The suitability of a visible light-curing resin as a repair material, ie, its bending strength, was examined. Results were compared to those obtained with a self-curing acrylic resin. The visible light-curing resin led to repairs with lower strength.
A Series of Pesticides Based on Fluorine Monomer (2011)

The application in pesticide field of fluorine-containing monomers including tetrafluoroethylene,hexafluoropropylene,perfluoromethyl vinyl ether and chlorodifluoromethane were introduced in this article.Their application fields included insecticides,fungicides and herbicides,which pointed out a new way to use fluorine-containing monomers for the fluorine chemical industry.
DisguiseNet: A Contrastive Approach for Disguised Face Verification in the Wild (2018)

This paper describes our approach for the Disguised Faces in the Wild (DFW) 2018 challenge. The task here is to verify the identity of a person among disguised and impostors images. Given the importance of the task of face verification it is essential to compare methods across a common platform. Our approach is based on VGG-face architecture paired with Contrastive loss based on cosine distance metric. For augmenting the data set, we source more data from the internet. The experiments show the effectiveness of the approach on the DFW data. We show that adding extra data to the DFW dataset with noisy labels also helps in increasing the gen 11 eralization performance of the network. The proposed network achieves 27.13% absolute increase in accuracy over the DFW baseline.
Colocalization of Glucagon‐Like Peptide‐1 (GLP‐1) Receptors, Glucose Transporter GLUT‐2, and Glucokinase mRNAs in Rat Hypothalamic Cells: Evidence for a Role of GLP‐1 Receptor Agonists as an Inhibitory Signal for Food and Water Intake (1996)

This study was designed to determine the possible role of brain glucagon-like peptide-1 (GLP-1) receptors in feeding behavior. In situ hybridization showed colocalization of the mRNAs for GLP-1 receptors, glucokinase, and GLUT-2 in the third ventricle wall and adjacent arcuate nucleus, median eminence, and supraoptic nucleus. These brain areas are considered to contain glucose-sensitive neurons mediating feeding behavior. Because GLP-1 receptors, GLUT-2, and glucokinase are proteins involved in the multistep process of glucose sensing in pancreatic beta cells, the colocalization of specific GLP-1 receptors and glucose sensing-related proteins in hypothalamic neurons supports a role of this peptide in the hypothalamic regulation of macronutrient and water intake. This hypothesis was confirmed by analyzing the effects of both systemic and central administration of GLP-1 receptor ligands. Acute or subchronic intraperitoneal administration of GLP-1 (7-36) amide did not modify food and water intake, although a dose-dependent loss of body weight gain was observed 24 h after acute administration of the higher dose of the peptide. By contrast, the intracerebroventricular (i.c.v.) administration of GLP-1 (7-36) amide produced a biphasic effect on food intake characterized by an increase in the amount of food intake after acute i.c.v. delivery of 100 ng of the peptide. There was a marked reduction of food ingestion with the 1,000 and 2,000 ng doses of the peptide, which also produced a significant decrease of water intake. These effects seemed to be specific because i.c.v. administration of GLP-1 (1-37), a peptide with lower biological activity than GLP-1 (7-36) amide, did not change feeding behavior in food-deprived animals. Exendin-4, when given by i.c.v. administration in a broad range of doses (0.2, 1, 5, 25, 100, and 500 ng), proved to be a potent agonist of GLP-1 (7-36) amide. It decreased, in a dose-dependent manner, both food and water intake, starting at the dose of 25 ng per injection. Pretreatment with an i.c.v. dose of a GLP-1 receptor antagonist [exendin (9-39); 2,500 ng] reversed the inhibitory effects of GLP-1 (7-36) amide (1,000 ng dose) and exendin-4 (25 ng dose) on food and water ingestion. These findings suggest that GLP-1 (7-36) amide may modulate both food and drink intake in the rat through a central mechanism.
Nicotine, Tobacco Smoke, and Body Weight: A Review of the Animal Literature (1989)

Cigarette smokers weigh less than comparably aged non-smokers, and smokers who quit smoking commonly gain weight. Although these relationships are well-established, causality and mechanisms of action cannot be conclusively determined on the basis of human studies alone. This paper reviews the animal literature which has addressed the effects of exposure to nicotine or tobacco smoke on energy intake and energy expenditure. These studies indicate that nicotine causes changes in body weight and that these effects are mediated in part by changes in food consumption. In addition, changes in energy expenditure, especially changes in fat utilization, seem to be involved in the effects of nicotine on body weight.
An ELISA Assay for the Detection of Factor VIII Antibodies – Comparison with the Conventional Bethesda Assay in a Large Cohort of Haemophilia Samples (2002)

An enzyme-linked immunosorbent assay (ELISA) has been developed to measure factor VIII antibodies in haemophilia patients. The assay utilizes binding of the antibodies in the plasma to solid phase antigen, i.e. recombinant factor VIII which was subsequently detected by a human polyclonal IgG labelled with the alkaline phosphatase-p-nitrophenyl phosphate substrate system. Comparisons were made with the Bethesda assay for the quantitation of factor VIIII inhibitors. Dose response curves for the reference standards were consistently linear and reproducible. The assay was specific for factor VIII antibodies, showing a negative reaction for antibodies to other coagulation factors, antinuclear factors and antiphospholipid antibodies. Using this method, 312 samples from haemophilia A patients and 31 samples from healthy controls were screened for the presence of inhibitors and compared with the conventional Bethesda assay. Twenty-four cases were found to be positive for inhibitors in both the ELISA and Bethesda assay. Five additional cases were also found to be positive in the ELISA assay, which, however, were negative in Bethesda assay. One patient who was initially positive for factor VIII inhibitors both by the Bethesda assay and ELISA eventually became negative for the Bethesda assay (<0.5 BU/ml) but was still positive for the ELISA assay. The ELISA thus described had a specificity of 97.8% and a sensitivity of 100% when tested against a large cohort of haemophilia A samples.
Polycystic ovary syndrome (PCOS) and hyperandrogenism: the role of a new natural association. (2015)

This new myo-inositol, monacolin K and lipoic acid association contains appropriate substances to contrast various etiopathogenic elements responsible for the onset of PCOS and the symptoms of hyperandrogenism and dyslipidemia related to it.
The Role of Fatty Acids and Eicosanoid Synthesis Inhibitors in Breast Carcinoma (1995)

We have reviewed the literature concerning the role of fatty acids and eicosanoid synthesis inhibitors in breast carcinoma. The omega-6 polyunsaturated fatty acids (PUFAs), primarily linoleic acid, promote breast cancer tumorigenesis and tumor cell proliferation directly and indirectly via increased synthesis of cyclooxygenase- and lipoxygenase-catalyzed products. The omega-3 PUFAs, primarily docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA), suppress breast carcinoma tumorigenesis and tumor cell proliferation, although the effect of DHA may be partly ascribed to increased amounts of EPA derived from DHA. Both cyclooxygenase and lipoxygenase inhibitors suppress tumorigenesis and/or tumor proliferation, with the latter being more active. Thus, arachidonic acid-derived eicosanoids play an important role in breast cancer, and the balance of the various eicosanoids may be a critical determinant of cell proliferation. However, the exact mechanism by which fatty acids and eicosanoid synthesis inhibitors exert stimulatory and inhibitory effects on breast carcinoma is still not well understood.