gebhart/patrepeval huggingface dataset:
Relevance of ancient myths in contemporary marital domesticity: a study in Shashi Deshpande's That Long Silence (2015)

Myths are very important dimensions of cultural and literary experiences. In the modern age, they have become powerful instruments in the preservation of both history and culture. Literary works tends to create or recreate certain mythical narratives which human beings consider crucial to their understanding of the world. Though it surpasses the ordinary human world, traditional values in the form of Hindu scriptures dominate the minds of human beings even today. The scriptures emphasize fulfilling obligations of domesticity and make the man-woman partnership in marriage an indissoluble bond which continues even in contemporary lives. But the rationalization within Hindu moral philosophy at the level of “dharma ” and “karma ” works, interestingly, more to subdue and reconcile woman rather than man to her unavoidable marital domestic duty. Shashi Deshpande has carved a niche in Indian Writing in English as a novelist, short story writer and non-fiction prose writer. Deshpande limits her narrative universe to the issues nearer the domestic space. It is within this space women lies at the core of her novels. Her fictional world focuses on the contemporary urban women caught in the vortex of their socio-cultural existence attempting to resist the dominant scripture of Hindu mythology in their endeavour to establish their identity situated within the marital domesticity. This paper would throw light on Deshpande’s use myths to show how they are deeply rooted in the psyche of the Indian people and their relevance in contemporary marital domesticity in her novel That Long Silence(1988).
Aggregators’ Optimal Bidding Strategy in Sequential Day-Ahead and Intraday Electricity Spot Markets (2017)

This paper proposes a probabilistic optimization method that produces optimal bidding curves to be submitted by an aggregator to the day-ahead electricity market and the intraday market, considering the flexible demand of his customers (based in time dependent resources such as batteries and shiftable demand) and taking into account the possible imbalance costs as well as the uncertainty of forecasts (market prices, demand, and renewable energy sources (RES) generation). The optimization strategy aims to minimize the total cost of the traded energy over a whole day, taking into account the intertemporal constraints. The proposed formulation leads to the solution of different linear optimization problems, following the natural temporal sequence of electricity spot markets. Intertemporal constraints regarding time dependent resources are fulfilled through a scheduling process performed after the day-ahead market clearing. Each of the different problems is of moderate dimension and requires short computation times. The benefits of the proposed strategy are assessed comparing the payments done by an aggregator over a sample period of one year following different deterministic and probabilistic strategies. Results show that probabilistic strategy reports better benefits for aggregators participating in power markets.
Formal Synthesis of Uvaricin via Palladium-Mediated Double Cyclization (2001)

[see reaction]. A novel palladium-mediated, ligand-controlled double cyclization is reported. The C2-symmetric diene produced was desymmetrized via Sharpless asymmetric dihydroxylation and was further transformed into a known intermediate in the synthesis of uvaricin.
Automatic muscle and fat segmentation in the thigh from <i>T</i>1‐Weighted MRI (2015)

The proposed automatic segmentation approach provides adequate thigh tissue segmentation and may be helpful in studies of regional composition.
BCL2 regulates neural differentiation. (1996)

A main function attributed to the BCL2 protein is its ability to confer resistance against apoptosis. In addition to the constitutively high expression of BCL2, caused by gene rearrangement in follicular lymphomas, elevated expression of the BCL2 gene has been found in differentiating hematopoietic, neural, and epithelial tissues. To address the question of whether the expression of BCL2 is a cause or consequence of cell differentiation, we used a human neural-crest-derived tumor cell line, Paju, that undergoes spontaneous neural differentiation in vitro. The Paju cell line displays moderate expression of BCL2, the level of which increases in parallel with further neural differentiation induced by treatment with phorbol 12-myristate 13-acetate. Transfection of normal human BCL2 cDNA in sense and antisense orientations had a dramatic impact on the differentiation of the Paju cells. Overexpression of BCL2 cDNA induced extensive neurite outgrowth, even in low serum concentrations, together with an increased expression of neuron-specific enolase. Paju cells expressing the anti-sense BCL2 cDNA construct, which reduced the endogenous levels of BCL2, did not undergo spontaneous neural differentiation. These cells acquired an epithelioid morphology and up-regulated the intermediate filament protein nestin, typically present in primitive neuroectodermal cells. The manipulated levels of BCL2 did not have appreciable impact on cell survival in normal culture. Our findings demonstrate that the BCL2 gene product participates in the regulation of neural differentiation.
Polymyxin B Moderates Acidosis and Hypotension in Established, Experimental Gram-Negative Septicemia (1987)

Polymyxin B (PMB), an antibiotic, and sodium deoxycholate (NaD), a bile salt, are surface-active agents. Each protected mice against an otherwise lethal challenge with purified endotoxin (P less than .001). To determine if either of these agents was effective in treating established, overwhelming gram-negative septicemia, we infected rabbits by intraperitoneal injection of Escherichia coli K1. Animals were treated with moxalactam 1 hr after infection, then randomly assigned to groups receiving either saline, PMB, or NaD. Serial samples of blood were assayed for bacterial concentration, levels of plasma endotoxin, arterial blood gases, and complete blood cell counts. Physiologic functions were monitored continuously. Although levels of bacteremia and endotoxemia were similar in all three groups, rabbits receiving PMB had significantly higher mean arterial blood pressure, blood pH, and bicarbonate concentrations than did control rabbits (P less than .05). Rabbits receiving NaD fared no better than controls. In this model, PMB moderates some of the deleterious effects of established, overwhelming gram-negative bacterial sepsis.
Study on replicase (subunit) gene of papaya ringspot virus cloning, sequencing and construction of higher plant expression vector. (1994)

The ds-cDNA was synthesized using genomic RNA of papaya ringspot virus (PRSV) as template. The blunt-ended cDNA was cloned into the EcoRV site of vector pBluescript SK. From the recombinants, the NIb gene of PRSV was obtained, and its complete sequence was also determined. After the NIb gene was modified through PCR, a binary vector of PRSV-NIb gene was constructed for its expression in higher plants.
Bax is an important determinant of chemosensitivity in pediatric tumor cell lines independent of Bcl-2 expression and p53 status. (1998)

Susceptibility of a tumor cell to undergo chemotherapy-induced apoptosis appears to be dependent upon the balance of proapoptotic and survival factors that are expressed within any given cell. We have chosen to evaluate how expression of several of these proteins influences chemosensitivity of a panel of 10 pediatric tumor cell lines chosen from three tumor histiotypes: neuroblastoma, rhabdomyosarcoma, and pediatric glial tumors. The proteins evaluated were p53 and six members of the Bax/Bcl-2 family: three proapoptotic proteins (Bax, Bak, and Bcl-xS) and three survival factors (Bcl-2, Bcl-xL, and Mcl-1). We investigated whether there was any relationship between endogenous expression of these proteins and chemosensitivity (or resistance) to three chemotherapeutic agents that directly damage DNA (doxorubicin, actinomycin D, and topotecan) and a mitotic spindle poison (vincristine). Even though exogenous overexpression of wild-type p53 has been associated with a chemosensitive phenotype in several model systems we demonstrated no such relationship in these studies. In addition, expression levels of Bcl-2, Bcl-xL, Bcl-xS, Bak, or Mcl-1 did not correlate with sensitivity or resistance to the four drugs. However, there was a statistically significant correlation between endogenous levels of Bax protein and sensitivity to both doxorubicin and actinomycin D. We conclude that even though many proteins such as p53 and Bcl-2 have been shown to influence drug response when exogenously overexpressed in model systems, in unmodified cell lines endogenous protein levels may not generate the same results. We have demonstrated that endogenous Bax expression was the only protein found to be associated with chemosensitivity across the three different tumor histiotypes and propose that analysis of Bax may be a more useful prognostic indicator for tumor response to therapy than either p53 or Bcl-2.
Basic principles and current applications of lung ultrasonography in the intensive care unit (2010)

Until recently, the sonographic visualization of pulmonary and pleural diseases was considered a poorly accessible method, due to the inability of sound to penetrate air-filled lung. Despite its limitations, lung ultrasonography is becoming an important diagnostic tool in a growing number of pathological situations such as pneumonia, atelectasis, interstitial-alveolar syndrome, pulmonary embolism, pneumothorax and pleural effusion. The low sensitivity of CXR and the difficulties of performing CT make this technique invaluable for bedside use in the intensive care unit. Lung ultrasonography is an easily repeatable and radiation-free technique, and therefore, an attractive imaging tool for use on a daily basis, especially in the management of critically ill patients.
An Adaptive Approach to Exergames with Support for Multimodal Interfaces (2013)

Technology such as television, computers, and video games are often in the line for reasons of why people lack physical activity and tend to gain weight and become obese. In the case of video games, with the advent of the so called “serious games initiative”, a new breed of video games have come into place. Such games are called “exergames” and they are intended to motivate the user to do physical activity. Although there is some evidence that some types of Exergames are more physically demanding than traditional sedentary games, there is also evidence that suggests that such games are not really providing the intensity of exert that is at the recommended levels for a daily exercise. Currently, most exergames have a passive approach. There is no real tracking of the players progress, there is no assessment of his/her level of exert, no contextual information, and there is no adaptability on the game itself to change the conditions of the game and prompt the desired physiological response on the player. In this thesis we present research work done towards the design and development of an architecture and related systems that support a shift in the exertion game paradigm. The contributions of this work are enablers in the design and development of exertion games with a strict serious game approach. Such games should have “exercising” as the primary goal, and a game engine that has been developed under this scheme should be aware of the exertion context of the player. The game should be aware of the level of exertion of the player and adapt the gaming context (in-game variables and exertion interface settings) so that the player can reach a predefined exertion rate as desired. To support such degree of adaptability in a multimedia, multimodal system, we have proposed a system architecture that lays down the general guidelines for the design and development of such systems.
Model calculations of the response of CZT strip detectors (1999)

Position-sensitive CZT detectors for research in astrophysics in the five - several hundred keV range are being developed by several groups. These are very promising for large area detector arrays in coded mask imagers and small-area focal plane detectors for focusing x-ray telescopes. We have developed detectors with crossed-strip readout and optimized strip widths and gaps to improve energy resolution. A 'steering electrode' is employed between the anode strips to improve charge collection. A model of charge drift in the detectors and charge induction on the electrodes has been developed to allow us to better understand these types of detectors and improve their design. The model presently accounts for the electric field within the detector, the charges' trajectories, mobility and trapping of holes and electrons, and charge induction on all electrodes including their time dependence. Additional effects are being added. The model is described and its predictions are compared with laboratory measurements. Results include (1) the dependence of anode, cathode and steering electrode signal on interaction depth, transverse position, electron and hole trapping, strip width and gap, and bias, (2) trajectories of charges for various anode and steering electrode bias voltages, (3) a method to improve energy resolution by sign depth of interaction information, and (4) an electrode geometry and bias optimized for the improved energy resolution. In general, the model provides good agreement with the measurements.
Pre-Authenticated and Adaptive IP Mobility for WLAN nodes (2006)

When a mobile node roams to another network/subnet, new resource reservation has to be made between the sender and receiver. If enough resources are not available, the quality of service may be disrupted and the connection may fail. If resources are reserved indiscriminately, then most of them would be unused and performance degradation would be the result. We would like to propose a pre-authenticated and adaptive micro-mobility management architecture in IP networks. We use pre-authentication to hasten the handoff process. Also the mobility predictor block used will help in reserving the resources aptly. The packets are generally classified based on the ToS field in IPv4 (or traffic class and the flow label fields in IPv6). Here we focus more on the special case of wireless local area networks (WLANs) installation within a building or in a restricted campus. In this paper, we propose a fast and adaptive IP micro mobility management scheme with mobility prediction for WLAN nodes. We also present some basic simulation on WLAN mobile node roaming
Influence of plasma induced damage during active etch on silicon defect generation (2002)

The role of plasma induced damage during active nitride etch in silicon defect generation was investigated. A correlation was established between the overetch pattern and surface densities of stacking faults and dislocations. High junction leakage and yield loss were observed in areas of the wafer subjected to excessive overetch. Optimization of overetch time resulted in defect free wafers and significant yield improvement.
ras-transformed NIH 3T3 cell lines, selected for metastatic ability in chick embryos, have increased proportions of p21-expressing cells and are metastatic in nude mice. (1990)

We previously reported that ras-transformed NIH 3T3 cells could be selected in vivo for increased metastatic ability after intravenous injection into chick embryos, and that the metastatic cell populations expressed increased levels of ras p21 protein. We have tested the metastatic ability of a series of these cells in nude mice, to determine if their properties in the chick embryo experimental metastasis assay predict their metastatic behavior in nude mice. We report here that cells selected for metastatic ability in the chick embryo are also metastatic when assayed in nude mice. We also asked whether the selected cells uniformly expressed higher levels of p21, using an immunocytochemical procedure. We found that p21 expression among individual cells in these populations was quite heterogeneous. There was a direct relationship between the proportions of p21-expressing cells and metastatic ability in both assays, with increased proportions of p21-expressing cells in cell lines selected for metastatic ability. Our results suggest that (a) the experimental (i.v.) metastasis assay in the chick embryo offers an efficient and cost-effective procedure for the identification and selection of cells that are also experimentally metastatic in nude mice, and (b) the metastatic properties of ras-transformed NIH 3T3 cells are due to individual cells that express increased amounts of p21.
Iterative Chase-2 Algorithm using Threshold for Block Turbo Codes Decoding Design (2006)

In this paper, we introduce an approach to get better performance of block turbo codes (BTCs). We use threshold to limit the search for the maximum-likelihood codeword. Consequently, by using chase-2 algorithm, Euclidean distance will be calculated from smaller group of candidate codeword, and we can calculate reliability and extrinsic information easier and faster. So a faster iterative decoding process is achieved to take these extra threshold calculations into chase-2 algorithm for BTCs. We evaluate the performance of this decoding process on additive white Gaussian noise (AWGN) channel. And decoding complexity reduces a lot over the standard iterative decoding methods. We also add this idea into the hardware design of BTCs decoder. It also shows good reduction for number of operations.
A distributed system testing framework (2008)

Supervisory Committee Dr. Stephen Neville, Department of Electrical and Computer Engineering Supervisor Dr. Kin Li, Department of Electrical and Computer Engineering Departmental Member Dr. Daniel Hoffman, Department of Computer Science Outside Member Distributed systems are becoming increasingly common. However, the testing of these systems is difficult due to their non-linear, stochastic and dynamic behaviours, and limited application-level testing support. In this thesis, a prototype cluster computingbased test harness has been developed that can be used for performance testing on a variety of distributed systems. Its usefulness is demonstrated through tests conducted on an example distributed system, including using the test harness to perform a parameter search on the system in an iterative fashion.
How and When Do Myocytes Die During Ischemia and Reperfusion: The Late Phase (2011)

While the majority of the cardiac myocyte death that makes up the final infarct occurs during ischemia and the first few minutes of reperfusion, cell death does not stop there. In fact necrosis and apoptosis, and potentially autophagy, can continue in the previously ischemic area for up to 3 days post-reperfusion. Several mechanisms can potentially contribute to this death continuum: (1) myocytes that have already passed the point of no return despite reperfusion; (2) continued dysfunction of the coronary microvasculature; and (3) infiltration of inflammatory cells. The latter in particular leads to elevated myocardial concentrations of reactive oxygen species (ROS), inflammatory cytokines, activation of toll-like receptors, secretion of toxic enzymes, and activation of the complement cascade--all of which can lead to myocyte death. However, there is a considerable lack of studies that comprehensively examine the time course, nature, and mechanisms of post-reperfusion myocyte death. Moreover, cell death types (apoptosis, necrosis, and autophagy) are inextricably linked to one another. Therefore, we do not know whether specific blockade of necrosis during the acute phase of myocyte death will instead enhance apoptosis during the late phase, that is, will we be simply delaying the inevitable? Consequently, the purpose of this article is to briefly review what we do, and more importantly what we do not, know about cardiac cell death in the reperfused heart and what is needed to advance our understanding of this phenomenon.
[On the stability of phenylmercury salts. Part 50: Contributions to problems concerning the use of plastic receptacles for liquid pharmaceuticals (author's transl)]. (1982)

The authors describe a dithizone method for the determination of phenylmercury salts that yields easily reproducible results on examining the stability of these preserving agents. Aqueous solutions of phenylmercury salts are instable already in glass bottles, but they are instable to a much greater extent in low-density polyethylene bottles. Their degradation is accelerated in the presence of chloride ions. When stored under nitrogen, the phenylmercury salt solutions show lower losses of preserving agents than when stored under normal air. The ultra-violet extinction of phenylmercury salt solutions increases during storage in glass bottles, and decreases during storage in plastic bottles. In plastic bottles, the degradation is associated with sorption.
Development of PVDF micro and nanostructures for cell culture studies (2012)

L'ingénierie tissulaire vise à réparer les tissus endommagés et à récupérer les fonctions biologiques correspondantes. Afin de restaurer un tissu endommagé tel que le système nerveux, la conception et la fabrication de nouveaux types d échafaudages tissulaires sont nécessaires. Dans ce travail, nous avons développé plusieurs techniques de microfabrication pour le polyfluorure de vinylidène (PVDF), un fluoropolymère thermoplastique, non réactif et piézoélectrique, qui peut être utilisé pour la culture cellulaire et l'ingénierie tissulaire. Nous avons tout d'abord étudié l'adhésion et la croissance cellulaire sur des substrats en PVDF avec des motifs micro et nanométriques en utilisant différentes techniques de fabrication telles que la micro-photolithographie, la lithographie douce, l impression par microcontact, etc. L'influence de la micro-structuration sur les activités piézo-électriques du PVDF a été caractérisée par différentes méthodes d'analyses de surface (FTIR, XRD). Par la suite, nous avons effectué une étude systématique sur la fabrication de nanofibres de PVDF et leur compatibilité avec la culture cellulaire. Enfin, nous avons démontré la possibilité de doper ces nanofibres avec des nanoparticules magnétiques ce qui les rends excitables à distance par un champ magnétique
Leukocyte CD11b and CD18 expression are increased in blood salvaged for autotransfusion. (1994)

To investigate whether activated leukocytes are present in salvaged blood, we measured complete blood counts and quantified the surface expression of the leukocyte adhesion receptors CD11b and CD18 in salvaged blood and arterial blood from six male patients undergoing elective abdominal aortic aneurysm repair. Salvaged blood contained 5,450 +/- 1010 leukocytes/microL and 7600 +/- 6200 platelets/microL and had a hematocrit of 50.6 +/- 3.7%. CD 11b expression was 3.3 +/- 0.5 fold higher on neutrophils and 3.8 +/- 1.0 fold higher on monocytes from salvaged blood compared with arterial blood (P < 0.05 for both). CD18 expression was increased 3.2 +/- 0.2 fold on neutrophils and 2.5 +/- 0.4 fold on lymphocytes (P < 0.05) in salvaged compared to arterial blood (P < .05). Monocyte expression of CD18 was increased 4.50 +/- 1.1 fold in salvaged blood, but this difference was not statistically significant. We conclude that a substantial number of activated leukocytes are present in salvaged blood. Because activated leukocytes could potentially be detrimental to the recipient, our findings raise theoretical concerns about the use of salvaged blood and emphasize the need for further refinement of the procedure.
Adenosine triphosphate levels in human plasma. (1996)

The predictable sharp fall in plasma ATP levels induced by venipuncture and the clear diurnal variation suggest that plasma contains ATP independent of platelet dense body release and endothelial cell needle trauma. Synovial plasma flow at peak (600 nM) levels is insufficient to provide more than one-third of the extracellular ATP needed to generate inorganic pyrophosphate in articular tissues.