gebhart/patrepeval huggingface dataset:
Analysis and Optimization of Mobile Business Processes (2012)

Mobility of workers and business processes rapidly gains the attention of businesses and business analysts. A wide variety of definitions exists for mobile business processes. This work considers a type of business processes concerned with the maintenance of distributed technical equipment as, e.g., telecommunication networks, utility networks, or professional office gear. Executing the processes in question, workers travel to the location where the equipment is situated and perform tasks there. Depending on the type of activities to be performed, the workers need certain qualifications to fulfill their duty. Especially in network maintenance processes, activities are often not isolated but depend on the parallel or subsequent execution of other activities at other locations. Like every other economic activity, the out- lined mobile processes are under permanent pressure to be executed more efficiently. Since business process reengineering (BPR) projects are the common way to achieve process improvements, business analysts need methods to model and evaluate mobile business processes.<br><br> Mobile processes challenge BPR projects in two ways: (i) the process at- tributes introduced by mobility (traveling, remote synchronization, etc.) complicate process modeling, and (ii) these attributes introduce process dynamics that prevent the straightforward prediction of BPR effects. This work solves these problems by developing a modeling method for mobile processes. The method allows for simulating mobile processes considering the mobility attributes while hiding the complexity of these attributes from the business analysts modeling the processes.<br><br> Simulating business processes requires to assign activites to workers, which is called scheduling. The spatial distribution of activities relates scheduling to routing problems known from the logistics domain. To provide the simula- tor with scheduling capabilities the according Mobile Workforce Scheduling Problem with Multitask-Processes (MWSP-MP) is introduced and analyzed in-depth. A set of neighborhood operators was developed to allow for the application of heuristics and meta-heuristics to the problem. Furthermore, methods for generating start solutions of the MWSP-MP are introduced. <br><br> The methods introduced throughout this work were validated with real-world data from a German utility. The contributions of this work are a reference model of mobile work, a business domain independent modeling method for mobile business processes, a simulation environment for such processes, and the introduction and analysis of the Mobile Workforce Scheduling Problem with Multitask-Processes.
p21WAF1/CIP1/SDI1 is elevated through a p53-independent pathway by mimosine. (1996)

Tumor suppressor p53 is a nuclear protein that is induced by DNA damage and is involved in G1 and G2 phase control of the cell cycle. p21WAF1/CIP1/SDI1 (p21), a cyclin-dependent kinase inhibitor, is a downstream target and effector of p53 to induce G1 arrest. Mimosine is a potent reversible late G1 phase blocker of the cell cycle. In this study, we showed that mimosine can increase both p21 mRNA and protein levels, indirectly inhibit cyclin E-associated kinase activity without affecting the cyclin E protein level, block human breast cancer cells (21PT) in the late G1 phase of the cell cycle, and induce a p53-independent p21 pathway in these cells. These results support the possibility of restoring a G1 checkpoint by use of mimosine. They also suggest that the mechanism of the effect of mimosine is complex and may have more than one target in the cell.
Active Flutter Suppression Systems for Military Aircraft. A Feasibility Study (1973)

This analytical study of active flutter suppression systems for military aircraft was directed toward the accomplishment of two broad objectives: (1) Establish flutter modes, configurations, and flight conditions where active flutter control can show an advantage; (2) Formulate design guidelines and criteria to implement and test active flutter suppression systems. To accomplish these broad objectives the study effort was divided into the three separate investigations: (1) Wing/store flutter control study - to assess the practicality of extension of flutter boundaries for several store combinations; (2) All-movable horizontal tail flutter control study - to investigate both the potential payoff in future aircraft and the unique problems and difficulties when one of the participants in the flutter mechanism is used as the flutter control force producer; (3) Wing flutter control study - to parametrically evaluate the potential payoff in future aircraft by active flutter control of flutter critical primary lifting surfaces.
Hierarchical graphics databases in sort-first (1997)

Article Free Access Share on Hierarchical graphics databases in sort-first Author: Carl Mueller UNC-CH Computer Science UNC-CH Computer ScienceView Profile Authors Info & Claims PRS '97: Proceedings of the IEEE symposium on Parallel renderingOctober 1997Pages 49–ff.https://doi.org/10.1145/266638.266652Published:20 October 1997Publication History 10citation313DownloadsMetricsTotal Citations10Total Downloads313Last 12 Months15Last 6 weeks4 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Publisher SiteeReaderPDF
Acidic tumor microenvironment in human melanoma (2016)

One characteristic of solid tumors such as malignant melanoma is the acidification of the tumor microenvironment. The deregulation of cancer cell metabolism is considered a main cause of extracellular acidosis. Here, cancer cells utilize aerobic glycolysis instead of oxidative phosphorylation even under normoxic conditions, as originally described by Otto Warburg. These metabolic alterations cause enhanced acid production, especially of lactate and carbon dioxide (CO2 ). The extensive production of acidic metabolites and the enhanced acid export to the extracellular space cause a consistent acidification of the tumor microenvironment, thus promoting the formation of an acid-resistant tumor cell population with increased invasive and metastatic potential. As melanoma is one of the deadliest and most metastatic forms of cancer, understanding the effects of this extracellular acidosis on human melanoma cells with distinct metastatic properties is important. The aim of this review was to summarize recent studies of the acidification of the tumor microenvironment, focusing on the specific effects of the acidic milieu on melanoma cells and to give a short overview of therapeutic approaches.
主题企划SQL Server 2005走下楼梯——集成的价值：SQL Server 2005和Visual Studio 2005——Paul Flessner和S．Somasegar访谈录 (2005)

微软将SQL Server2005和Visual Studio 2005集成在一起发布。并首次集成在一起。其价值何在？本刊就此专访了微软负责这两项产品的副总裁Paul Flessner和S．Somasegar。
Tumor Necrosis Factor-α Activates Smooth Muscle Cell Migration in Culture and Is Expressed in the Balloon-Injured Rat Aorta (1997)

In experimental models of atherosclerosis, activation of smooth muscle cell (SMC) migration from the media to the intima is preceded by intimal accumulation of inflammatory cells, suggesting that cytokines may be involved in this process. The present study demonstrates that tumor necrosis factor-alpha (TNF-alpha) regulates cytoskeletal organization of SMCs by inducing depolymerization of actin stress fibers and dispersion of vinculin from sites of focal adhesion and stimulates the migration of cultured human SMCs in a dose-dependent manner. Moreover, TNF-alpha induces rapid activation of the c-ets-1 gene, which codes a transcription factor known to regulate enzymes important for matrix degradation during cell migration. Balloon catheter injury of the rat femoral artery resulted in medial expression of TNF-alpha within 6 hours. This expression appeared to be localized to SMCs and remained elevated until SMCs began to migrate into the intima 7 days after injury. These findings demonstrate that TNF-alpha has a stimulatory effect on SMC migration and suggest that TNF-alpha may be involved in the intimal recruitment of SMCs during plaque formation.
Development of a High-Pressure/High-Temperature Downhole Turbine Generator (2007)

The objective of this project as originally outlined has been to achieve a viable downhole direct current (DC) power source for extreme high pressure, high temperature (HPHT) environments of >25,000 psi and >250 C. The Phase I investigation posed and answered specific questions about the power requirements, mode of delivery and form factor the industry would like to see for downhole turbine generator tool for the HPHT environment, and noted specific components, materials and design features of that commercial system that will require upgrading to meet the HPHT project goals. During the course of Phase I investigation the scope of the project was HPHT downhole DC power. Phase I also investigated the viability of modifying a commercial expanded, without additional cost expected to the project, to include the addition of HT batteries to the power supply platform.
Characteristics and Predictors of Missed Opportunities in Lung Cancer Diagnosis: An Electronic Health Record–Based Study (2010)

Preventable delays in lung cancer diagnosis arose mostly from failure to recognize documented abnormal imaging results and failure to complete key diagnostic procedures in a timely manner. Potential solutions include EHR-based strategies to improve recognition of abnormal imaging and track patients with suspected cancers.
CardBus system architecture (1996)

From the Publisher:
CardBus System Architecture describes 32-bit PC Cards, called CardBus PC Cards, and the hardware and software interfaces required to implement the new CardBus solution. This book focuses on the design and implementation of CardBus Cards and the host systems required to support them, including relationships and interaction between hardware and software elements associated with CardBus Cards and their host systems.
The Manufacture of Silver Azide R.D. 1336 (1950)

A previous report E.R.D.E. No. 17/R/49 "Silver Azide as a replacement for lead azide in detonators" described experiments carried out on the preparation and properties of this substance and discussed its possible development as an initiator for Service detonators. The results justified the recommendations for further trials on performance and stability and also for the continued development of the method of preparation. As a result of these further investigations it is now possible to describe a detailed manufacturing process for silver azide; this is the object of the present report.
Market-Process Theory and "Dynamic" Theories of the Market (1990)

Few constructs in neoclassical economics are as elegant and closely bound as the theories of perfect competition and pure monopoly. These theories represent indispensable items in the basic analytical toolbox of the modem neoclassical economist. Their formal derivation relies on the twin propositions that (a) individual agents are rational in the sense that they continuously maximize expected utility (or profits) given knowledge of objective function and constraints and (b) the equilibrium that results when agents (in isolation and in the aggregate) behave rationally describes the universe of relevant discourse. Economists engaged in the application of microeconomic theory to economic reality have learned, however, that conducting successful research requires the use of theoretical constructs that were not strictly a part of their technical training, and which appear to conflict with one or both of the above propositions. These constructs are largely comprised of the stories or bits of economic intuition that are thought merely to be heuristic devices to accompany the teaching of formal models. But they constitute in fact a logically distinct verbal (or what Nelson and Winter have termed appreciative) theory of what behavior looks like outside of equilibrium, where rationality (in the standard neoclassical sense defined above) need not serve as a useful rule for the individual decision-maker or, even less, as a useful approach for the economic theorist. Antitrust economists, for example, have long realized that few if any markets meet the structural conditions necessary for the optimal allocation of resources, or that exhibit the zero economic-profit result of the model of perfect competition (assuming economic profit can be accurately measured empirically [5, 219-69]). Similarly, they have come to suspect that the conditions for pure monopoly or the various forms of imperfect competition are rarely if ever met in practice. An economic theorist might respond to this state of affairs in one of two ways. The first is to attempt to expand the concept of rationality and the scope of equilibrium theorizing in order to incorporate, for example, the phenomena of price and output adjustment, product differentiation,
Wear mechanisms of coated carbide tools (1982)

AbstractAbstractCemented carbide inserts, both uncoated and coated with single or composite layers of TiC, TiN, or Al2O3, were used to cut En. 8 and En 24 steel at speeds between 183 and 305 min−1 Quick-stop specimens and tool-temperature estimates demonstrated that conditions at the tool/work interface were essentially similar for uncoated tools and for all types of coated tool tested. The flank and rake-face wear rates of coated tools were estimated to be respectively ∼ 10 and 100 times less than that of an uncoated carbide, smaller differences between the rates of flank and rake-face wear of TiC, TiN, and Al2O3 coatings being observed. On the rake face, wear of TiC coatings was by atomic diffusion and discrete plastic deformation, while TiN coatings and uncoated cemented carbide were worn by atomic diffusion. Al2O3 coatings were worn principally by discrete plastic deformation. Flank wear of both coated and uncoated tools was principally by atomic diffusion. Al2O3 and TiN coatings showed a greater resistance to groove formation at the outside edge of the depth of cut than TiC coatings, which were worn at a similar rate to the uncoated carbide inserts. Grooves were formed by two distinct mechanisms involving oxidation and fatigue cracking, both of which were accelerated when cutting in a jet of oxygen and eliminated when cutting in jets of argon or nitrogen.
Management of radiation wounds (2012)

Radiotherapy forms an integral part in cancer treatment today. It is used alone or in combination with surgery and chemotherapy. Although radiotherapy is useful to effect tumour death, it also exerts a deleterious effect on surrounding normal tissues. These effects are either acute or can manifest months or years after the treatment. The chronic wounds are a result of impaired wound healing. This impairment results in fibrosis, nonhealing ulcers, lymphoedema and radionecrosis amongst others. This article will discuss the pathophysiology in brief, along with the manifestations of radiation-induced injury and the treatment available currently.
The Effect of Bid Withdrawal in a Multi-Object Auction (1997)

The Federal Communications Commission currently utilizes a simultaneous multi-round ascending bid auction to allocate Personal Communication Services licenses. In the auction, participants are allowed to withdraw standing bids at a penalty. The penalty is equal to the difference between the price at which the bid was withdrawn and the highest bid after the withdrawal. The withdrawal rule was added to the auction design to assist bidders wishing to assemble combinations of licenses who may find themselves stranded with an assortment of licenses for which their bids sum to more than their value. This paper reports results of experiments that examine the effect of the withdrawal rule in environments in which losses can occur if packages of licenses must be assembled piecemeal. The experiments demonstrate that there is a tradeoff with using the rule: efficiency and revenue increase, but individual losses are larger. Furthermore, the increased efficiency does not outweigh the higher prices paid so that bidder surplus falls in the presence of the withdrawal rule.
Accuracy and Reproducibility of Nuclear/Cytoplasmic Ratio Assessments in Urinary Cytology Specimens (2017)

Visual quantitation of N/C ratio showed only a fair correlation with actual N/C ratio with correlation decreasing with increasing N/C ratio. In the critical range, 0.5-0.7 N/C ratio both interobserver correlation and correlation with true N/C ratio may be insufficiently accurate for precise category assignment as used in the Paris System. Diagn. Cytopathol. 2017;45:107-112. © 2016 Wiley Periodicals, Inc.
RECLAIM : California's guarantee for cleaner air (1994)

California's south coast air basin--the Los Angeles area--suffers the worst air pollution in the US, even after a history of extraordinary actions taken to reduce pollution. Existing regulations are tough and demanding, but must be changed to achieve federal clean air health standards by 2010. The Southern California business community and public are aggressively pursuing use of market incentives to lower the cost of achieving cleaner air. The South Coast Air Quality Management District (SCAQMD) is developing an alternative market-based regulatory approach called the Regional Clean Air Incentives Market (RECLAIM) program. RECLAIM has the potential to clean up air more effectively than traditional regulations by harnessing the power of the marketplace. Compared to the existing Air Quality Management Plan (AQMP), RECLAIM is designed to ensure that the program achieves equivalent emission reductions, an equal or greater level of enforcement, lower implementation costs, fewer job impacts and no adverse public health impacts.
Fuchs' Heterochromic Iridocyclitis Is Not Associated With Ocular Toxoplasmosis (1992)

To analyze the association between Fuchs' heterochromic iridocyclitis (FHI) and toxoplasmosis, we performed ocular examinations and used various specific laboratory tests to establish a role for Toxoplasma gondii in the pathogenesis of FHI. Results were compared with those for other types of uveitis and healthy controls. Of the 88 patients with FHI, nine (10.2%) had toxoplasmosislike scars, but an association could not be proved by the indirect immunofluorescence antibody test or enzyme-linked immunosorbent assay, or by a test for cellular immunity to Toxoplasma antigen. Analysis of aqueous humor samples for Toxoplasma antibodies in patients with FHI also yielded negative results. On the basis of the negative results of these laboratory tests, we concluded that FHI is not associated with ocular toxoplasmosis.
Enzyme linked immunosorbent assay for detecting adenoviruses in stool specimens: comparison with electron microscopy and isolation. (1990)

A commercial enzyme linked immunosorbent assay (ELISA) for detection of adenoviruses in stool samples was compared with the use of electron microscopy and isolation in Graham 293 cells. Although specific, the ELISA was less sensitive than both electron microscopy and isolation. The ELISA had an overall sensitivity of 78% and a specificity of 100%. The sensitivity was related to the amount of virus particles present in the stool sample, increasing to 90% with about 10(7) viral particles/ml of stool. The ELISA was easy to perform, requiring no instrumentation, and is a useful first line test for detection of adenoviruses in stool samples, especially in laboratories without access to an electron microscope. Wider use of ELISAs should help in evaluating the role of adenoviruses in viral gastroenteritis.
Bladder cancer: a review of diagnosis and management. (2000)

Bladder cancer is the fourth most commonly diagnosed malignancy in men and the eighth most common in women. It represents a spectrum of disease, ranging from superficial, well-differentiated disease, which does not significantly impact survival, to highly malignant tumors for which long term survival may be dismal. Transitional-cell carcinoma, which constitutes the vast majority of bladder cancers in the United States, may develop as carcinoma in situ or as invasive carcinoma. This article focuses on transitional-cell carcinoma with a review of the major aspects of the disease, including the epidemiology, diagnosis and staging, and management (including organ preservation). Therapeutic options are explored, including surgery, radiotherapy, chemotherapy, and combined modality therapy.
의사소통 윤리성에 대한 언어철학적 고찰 (2013)

In der kommunikativen Ethik wird nach bestimmten Werten gefragt, fur deren Realisierung sie Masstabe entwickeln soll. Hier handelt es sich um eine Form der Werteehtik, die nicht moralisch begrundbar ist. Eine solche kommunikative Ethik basiert auf den Grice’schen Maximen. Grice (1975) geht davon aus, dass Kommunikation ein kooperativer Vorgang ist. In dieser Arbeit wird untersucht, ob die kommunikative Ethik anhand des Kooperationsprinzips von Grice und der Kategorien der Urteile von Kant interpretierbar und analysierbar ist, da beide Theorien bezuglich der Kategorien der Quantitat, der Qualitat, der Relation und der Modalitat gewisse Ahnlichkeiten aufweisen. Diese Kategorien beziehen sich sowohl auf synthetische Begriffe als auch auf die wahren Stammbegriffe des reinen Verstandes. In allen Urteilen wird nach Kant das Verhaltnis eines Subjekts zum Pradikat untersucht. Wenn das Pradikat B ganz auserhalb des Subjekts A liegt, wird es als synthetisch bezeichnet. In den synthetischen Urteilen ist ein Pradikat zu dem Begriffe des Subjekts durch Erweiterungsurteile hinzuzufugen. Durch einen Ruckgriff auf die Erfahrung wird die Erkenntnis erweitert. In dieser Hinsicht sind die synthetischen Urteile mit den konversationalen Implikaturen vergleichbar. Bei einem naheren Vergleich zwischen dem Kooperationsprinzip von Grice und den Kategorien der Urteile von Kant lasst sich namlich feststellen, dass die synthetischen Urteile von Kant den konversationalen Implikaturen von Grice sehr ahnlich sind. Die 12 logischen Funktionen des Verstandes in Urteilen und die 12 reinen Verstandesbegriffe von Kant sind fur die Analyse der kommunikativen Ethik sehr bedeutungsvoll und werden sogar viel konkreter und logischer als die Konversationsmaximen von Grice dargestellt. Besonders in Bezug auf die Maxime der Relation fallt dies auf, da Kant diesen Begriff im Gegensatz zu Grice bezuglich der Wechselwirkung zwischen den Handelnden und den Leidenden sehr logisch und ausfuhrlich erklart. Abschliesend lasst sich feststellen, dass die 12 logischen Funktionen des Verstandes in Urteilen und die 12 reinen Verstandesbegriffe von Kant zur Erklarung der kommunikativen Ethik einen wichtigen Beitrag leisten und bis zum heutigen Zeitpunkt gultig und aktuell sind. In der vorliegenden Studie soll die Forschung in Bezug auf die kommunikativen Stile in Abhangigkeit von kulturellen Faktoren fortgesetzt werden.