gebhart/patrepeval huggingface dataset:
Solid immersion lens assisted resonant light scattering from a single quantum dot (2007)

Using index-matched GaAs immersion lens techniques we demonstrate a record (12%) extinction of a far-field focused laser by a single InAs/GaAs quantum dot. This extinction level enables resonant laser transmission spectroscopy without lock-in detection.
Improved motor and cognitive performance with sodium nitrite supplementation is related to small metabolite signatures: a pilot trial in middle-aged and older adults (2015)

Advancing age is associated with reductions in nitric oxide bioavailability and changes in metabolic activity, which are implicated in declines in motor and cognitive function. In preclinical models, sodium nitrite supplementation (SN) increases plasma nitrite and improves motor function, whereas other nitric oxide-boosting agents improve cognitive function. This pilot study was designed to translate these findings to middle-aged and older (MA/O) humans to provide proof-of-concept support for larger trials. SN (10 weeks, 80 to 160 mg/day capsules, TheraVasc, Inc.) acutely and chronically increased plasma nitrite and improved performance on measures of motor and cognitive outcomes (all p<0.05 or better) in healthy MA/O adults (62 ± 7 years). Untargeted metabolomics analysis revealed that SN significantly altered 33 (160 mg/day) to 45 (80 mg/day) different metabolites, 13 of which were related to changes in functional outcomes; baseline concentrations of 99 different metabolites predicted functional improvements with SN. This pilot study provides the first evidence that SN improves aspects of motor and cognitive function in healthy MA/O adults, and that these improvements are associated with, and predicted by, the plasma metabolome. Our findings provide the necessary support for larger clinical trials on this promising pharmacological strategy for preserving physiological function with aging.
Interobserver and Intraobserver Variability in the Cytologic Diagnosis of Normal and Abnormal Metaplastic Squamous Cells in Pap Smears (2001)

There was good interobserver agreement in classifying squamous metaplastic lesions. The agreement did not correlate with grade of dysplasia or experience of the cytopathologists. These findings should be considered in making treatment, quality assurance and legal decisions. A larger study is indicated to study interobserver and intraobserver variability and define cytologic criteria for lesions of metaplastic squamous cells.
Synthesis of a Potential 10E4 Tetrasaccharide Antigen Involved in Scrapie Pathogenesis. (2007)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
CW and pulsed Cr/sup 2+/:ZnS and ZnSe microchip lasers (2003)

Summary from only given. There is a growing demand for affordable, compact, room temperature operational and broadly tunable mid-infrared laser sources for use in a variety of remote sensing applications. The most impressive results have been obtained using Cr/sup 2+/:ZnSe crystals. Cr:ZnS and especially Cr:CdS have yet remained barely studied. In this paper we extend our effort to develop novel high optical density and high quality chromium doped ZnS, CdS, and ZnSe microchip laser crystals.
Context-Aware Confidence Sets for Fine-Grained Product Recognition (2019)

We present a new approach for fine-grained classification of retail products, which learns and exploits statistical context information about likely product arrangements on shelves, incorporates visual hierarchies across brands, and returns recognition results as “confidence sets” that are guaranteed to contain the true class at a given confidence level. Our system consists of three important components: 1) a nested hierarchy of product classes are automatically constructed based on visual similarities, 2) a confidence set predictor is trained based on class posteriors by using coarse-to-fine binary classifiers to discriminate each nested cluster of the hierarchy from the remainder of classes and a Bayesian network (BN) model that encodes the joint distribution of classifier scores with the fine-level class variable, and 3) n hidden Markov model (HMM) is trained with nested hidden states from the class hierarchy to model spatial transition across the nodes of product class hierarchy and resolve errors in the context-free confidence set results. Novel aspects of the proposed method include 1) combining confidence sets and context information via a HMM, 2) applying this concept to fine grained recognition of products arranged in retail shelves, and 3) presenting experimental results on four large datasets, collected from actual retail stores. We compare our approach with existing confidence set approaches and state-of-the-art convolutional neural networks classifiers including SENet-154, DenseNet-161, B-CNN, and Inception-Resnet-v2. Our approach performs comparably or better than state-of-the-art deep classifiers and exhibits high accuracy for relatively small confidence set sizes.
A roundtable discussion of antibiotic resistance: Putting the lessons to work (1999)

The following is an overview of open discussions held in conjunction with the Closed Roundtable Meeting on Resistant Bacteria. Participants discussed the management of antibiotic-resistant bacteria and developed strategies that hinder the development of additional strains of bacteria resistant to antimicrobial treatment. In addition, methods to communicate resistance-prevention strategies to primary care physicians were discussed.
Seroprevalence of antibody to hepatitis E virus among Chinese subjects in Taiwan (1994)

Recently, with an available serological hepatitis E virus diagnostic kit, the prevalence of IgG antibody to hepatitis E virus among Chinese subjects in Taiwan was evaluated by means of a solid-phase enzyme-linked immunoassay based on two recombinant hepatitis E virus antigens. The overall prevalence of hepatitis E virus antibody was 10.7% among 384 healthy subjects older than 20 yr but only 0.3% among 600 schoolchildren and young adolescents younger than 20 yr (p < 0.0001). Serial serum samples from 32 hepatitis E virus antibody-positive healthy subjects showed 84% of them to have antibodies persisting more than 3 to 8 yr. Among patients with viral hepatitis, IgG hepatitis E virus antibody was detected in 10% of 10 patients with acute hepatitis A, in 9.5% of 63 patients with acute hepatitis B and in 13.9% of 36 patients with acute posttransfusion hepatitis C. Of 77 patients with sporadic non-A, non-B hepatitis, IgG hepatitis E virus antibody was detected in 18.9% of 53 patients positive for antibody to hepatitis C virus and in 45.8% of 24 patients negative for hepatitis C virus antibody (p < 0.03). Most of our hepatitis E virus antibody-positive normal subjects and patients had never been abroad. These findings demonstrate that sporadic or subclinical hepatitis E virus infections also exist among the Chinese subjects in Taiwan. Hepatitis E virus infection may play an important role in patients with hepatitis C virus antibody-negative sporadic non-A, non-B hepatitis. IgG hepatitis E virus antibody in the sera of normal subjects may last for more than 8 yr.
ChemInform Abstract: A MODIFIED TRIESTER METHOD FOR THE SYNTHESIS OF DEOXYRIBOPOLYNUCLEOTIDES (1974)

Abstract Durch Kondensation der Nucleosid‐phosphate (I) und (II) in Gegenwart von Triisopropylbenzolsulfonylchlorid (TPS) werden die geschützten Dinucleotide (III) erhalten, die mit (IV) bzw. (II) die Trinucleotide (V) bzw. (VI) ergeben.
Respiratory Flow Estimation from Tracheal Sound by Adaptive Filters (2005)

In this study, average power of tracheal sound (Pave) was used to estimate flow by parametric method as well as adaptive filters as a nonparametric method. Based on some preliminary studies, an exponential model was used for describing the relationship between flow and Pave for parametric method. It was assumed that flow signal of at least one breath from each target flow is available for calibration. The error for flow estimation with parametric method, was found to be 9 ± 3 % and 10 ± 4 % for inspiration and expiration, respectively. Considering nonparametric method, the estimation error was the least for the third order adaptive filter using the average power of the tracheal sound (dB), which was 10 ± 3 % and 11 ± 4 % for inspiration and expiration, respectively.
Device-Independent Quantum Key Distribution (2015)

Device-independent quantum key distribution protocols allow distributing a secret key whose security does not rely on any assumption on the inner working of the devices in the implementation. We discuss recent progress on the problem.
Heart Dysfunction in Human Septic Shock (2002)

Although sepsis-induced alteration in cardiac performance is frequent, it is rarely clinically relevant. It occurs within 24 to 48 hours after the onset of sepsis in humans and involves both right and left ventricles. The coexistence of biventricular dilation remains controversial. However, recent data suggest that ventricular dilation is likely related to heavily fluid-resuscitated septic patients. Both reduction in cardiac performance and ventricular dilation recover within 6 to 8 days in septic patients who survive. Despite data suggesting a role for circulating cardiodepressing factors, increasing evidence is in favor of an intrinsic alteration in cardiac myofilament contractile function. Peroxynitrite rather than NO may play a role in this intrinsic alteration. In addition, reduction in myofilament response to calcium also plays an important role in sepsis-induced alteration in cardiac performance. Septic cardiomyopathy rarely needs a specific treatment. Thus, some patients with severe sepsis who do not increase, or who even reduce, cardiac index after adequate volume loading may need inotropic support. This is usually transient in patients who survive.
Allergic Reactions to Local Anesthetics in Dental Patients: Analysis of Intracutaneous and Challenge Tests (2011)

Some dental patients have histories of adverse reactions to local anesthesia. The aim of the present study was to investigate the frequency of allergy to local anesthetics of dental patients who had histories of adverse reactions to local anesthesia based on the results of allergy tests in our institute over a period of 5 years. We investigated the past medical records of dental patients retrospectively, and twenty patients were studied. Three of the 20 showed a positive or false-positive reaction in the intracutaneous test, and one patient showed a false-positive reaction in the challenge test. Our results suggest that the frequency of allergy to local anesthetics is low even if patients have histories of adverse reactions to local anesthesia. However, allergy tests of local anesthetics should be performed in patients in whom it is uncertain whether they are allergic.
Automatic Detection of Combed DNA (2010)

Extended abstract of a paper presented at Microscopy and Microanalysis 2010 in Portland, Oregon, USA, August 1 – August 5, 2010.
Effect of isotopic substitution on association with the sodium counterion (1993)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTEffect of isotopic substitution on association with the sodium counterionCheryl D. Stevenson, Eugene P. Wagner II, and Richard C. ReiterCite this: Inorg. Chem. 1993, 32, 11, 2480–2482Publication Date (Print):May 1, 1993Publication History Published online1 May 2002Published inissue 1 May 1993https://doi.org/10.1021/ic00063a046Request reuse permissionsArticle Views53Altmetric-Citations7LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (364 KB) Get e-Alertsclose Get e-Alerts
Studies on the Pseudouridinuria of Chronic Lymphocytic Leukemia (1964)

Abstract This paper reports a group of investigations attempting to explain the elevated pseudouridine excretion in the presence of normal uric acid excretion which occurs in chronic lymphocytic leukemia (CLL). Studies with isotopically labeled uric acid and adenine indicated that diversion of body purines from uric acid does not occur. Similarly the chemical analysis of the white cells in CLL did not reveal any excess content of pyrimidines, nor did the turnover of the ribonucleotides show any selective retention of purines as compared with pyrimidines. Studies with isotopically labeled orotic acid, however, indicated on overproduction of other pyrimidines as well as pseudouridine. Though no explanation has yet been found for the selective pyrimidine overproduction seen in CLL, a major portion of these pyrimidines appear to be derived from rapidly renewing sources.
Enzymes from isolates of Pseudomonas fluorescens involved in food spoilage (2002)

In the absence of ultrafiltration the presence of the minor protease species may be missed and they may act as contaminants of the major protease in unpurified or semipurified samples.
Interaction of Hydrophobically‐Modified Poly‐<i>N</i>‐isopropylacrylamides with Model Membranes—or Playing a Molecular Accordion (1991)

The thermoreversible coil-globule transition of polymers at the lower critical demixing temperature is a popular theme in polymer chemistry. Here, this phenomenon is exploited to induce a reversible contraction/expansion by temperature changes in a membrane-achored N-isopropylacrylamide copolymer (shown schematically below). With this liposome-anchored “molecular accordion” the dynamics of the cytoskeleton of biological systems can be roughly simulated.
Some Items of Interest to Process R&D Chemists and Engineers (2002)

ADVERTISEMENT RETURN TO ISSUEPREVEditorialNEXTSome Items of Interest to Process R&D Chemists and EngineersTrevor Laird, Stephen A. Hermitage, and Ulf TilstamView Author Information Editor GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire SG1 2NY, United Kingdom Lilly Development Centre S.A., B-1348 Mont-Saint-Guibert, BelgiumCite this: Org. Proc. Res. Dev. 2002, 6, 6, 742–748Publication Date (Web):October 22, 2002Publication History Published online22 October 2002Published inissue 1 November 2002https://pubs.acs.org/doi/10.1021/op0255985https://doi.org/10.1021/op0255985editorialACS PublicationsCopyright © 2002 American Chemical Society. This publication is available under these Terms of Use. Request reuse permissions This publication is free to access through this site. Learn MoreArticle Views1224Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail PDF (166 KB) Get e-AlertscloseSUBJECTS:Catalysts,Hydrocarbons,Metathesis,Salts,Solvents Get e-Alerts
Study of the charge radii of the stable lead isotopes (1981)

Isotope shifts have been measured of the K alpha /sub 1/ X-ray lines emitted after photo ionization of /sup 204/Pb, /sup 206/Pb, /sup 207 /Pb and /sup 208/Pb samples. The results are compared with theoretical values for delta (r/sup 2/) calculated with a microscopic model. The X-ray shift data are also compared with optical data and the nuclear parameters lambda derived from electron scattering results. (33 refs).
TNF inhibits insulin induced STAT5 activation in differentiated mouse muscle cells pmi28 (1998)

Tumor necrosis factor (TNF) plays a central role in the state of insulin resistance leading to type II diabetes. We here describe the crosstalk of TNF with insulin signaling cascades in the mouse muscle cell line pmi28. TNF downregulated insulin induced insulin receptor kinase activity and insulin induced activation of the transcription factor STAT5. Our results provide evidence that the inhibitory crosstalk between TNF and insulin in skeletal muscle cells comprises an interference with the expression of STAT5 regulated genes which may play an important role in the manifestation and/or progression of insulin resistance in muscle cells.
<title>Three-dimensional display of cortical anatomy and vasculature: MR angiography versus multimodality integration</title> (1990)

We present two methods for acquiring and viewing integrated 3-D images of cerebral vasculature and cortical anatomy. The aim of each technique is to provide the neurosurgeon or radiologist with a 3-D image containing information which cannot ordinarily be obtained from a single imaging modality. The first approach employs recent developments in MR which is now capable of imaging flowing blood as well as static tissue. Here, true 3-D data are acquired and displayed using volume or surface rendering techniques. The second approach is based on the integration of x-ray projection angiograms and tomographic image data, allowing a composite image of anatomy and vasculature to be viewed in 3-D. This is accomplished by superimposing an angiographic stereo-pair onto volume rendered images of either CT or MR data created from matched viewing geometries. The two approaches are outlined and compared. Results are presented for each technique and potential clinical applications discussed.
063 Wide Variation in Postoperative Urologic Surgery Opioid Prescribing in Tertiary Care Centers (2019)

The United States is facing an opioid epidemic and urologists must take action to minimize the risk of opioid dependence and diversion for their patients. However, literature surrounding postoperative pain management in urology is sparse. To assess postoperative opioid prescribing practices in a large cohort of patients undergoing urologic surgery. We identified patients who underwent 21 procedures at three associated tertiary care facilities from January1, 2015 to December 31, 2016. After converting prescribed opioids to oral morphine equivalents (OME), prescribing patterns were compared within and across procedures. For reference, 200 OME equals approximately twenty-six 5-mg oxycodone tablets. Univariate and multivariable statistical analysis was performed to evaluate variations based on demographic and perioperative/postoperative variables. 229/11,829 patients (78%) were prescribed an opioid at discharge. The median [interquartile range (IQR)] OME prescribed was 150 (75;225), and was greater than 200 in the majority of procedures (12/21; 57%). Striking variation in prescribing patterns was observed within and across surgical procedures. For instance, IQR ranges ≥ 150 were observed for open cystectomy [(median; IQR) 300; 210:375], open radical nephrectomy (300; 225:375), retroperitoneal node dissection (300; 225:375), hand-assisted laparoscopic nephrectomy (225; 150:300), and penile prosthesis (225; 150:315). On multivariable analysis younger age, cancer diagnosis, and inpatient hospitalization were associated with a higher likelihood of receiving a highest quartile OME prescription. 30-day refill rates varied from 2 to 26%. Refill rates were higher in those patients receiving more opioids at discharge.
Integration & automation: From protection to advanced energy management systems (2013)

This paper proposes an integrated and seamless infrastructure for protection, control and operation of an electric power system. At the lower level we propose a on dynamic state estimation of a protection zone for the purpose of providing protection for the zone. This scheme simplifies the protection approach for the zone by not requiring coordination with other protection zones (setting-less protection). The scheme provides the real time dynamic model of the zone as well as the real time operating conditions. The scheme can be also implemented in present day numerical relays with GPS synchronization. Using this basic protection infrastructure, we propose that the real time model of substation be autonomously created, send to the control center where the real time model of the system is also autonomously created. The system wide real time model is used to perform system optimization functions, and then send commands back through the same communication structure to specific power system components. Since protection is present in any power apparatus the proposed approach is realizable with very small investment. The availability of the real time dynamic state of the system enables the seamless integration of applications in the proposed system. Three applications are discussed in the paper: (a) setting-less protection, (b) stability monitoring, and (c) voltage/var control.
Sparsity-Exploiting Robust Multidimensional Scaling (2012)

Multidimensional scaling (MDS) seeks an embedding of N objects in a p <; N dimensional space such that inter-vector distances approximate pairwise object dissimilarities. Despite their popularity, MDS algorithms are sensitive to outliers, yielding grossly erroneous embeddings even if few outliers contaminate the available dissimilarities. This work introduces robust MDS approaches exploiting the degree of sparsity in the outliers present. Links with compressive sampling lead to robust MDS solvers capable of coping with unstructured and structured outliers. The novel algorithms rely on a majorization-minimization approach to minimize a regularized stress function, whereby iterative MDS solvers involving Lasso and sparse group-Lasso operators are obtained. The resulting schemes identify outliers and obtain the desired embedding at computational cost comparable to that of their nonrobust MDS alternatives. The robust structured MDS algorithm considers outliers introduced by a sparse set of objects. In this case, two types of sparsity are exploited: i) sparsity of outliers in the dissimilarities; and ii) sparsity of the objects introducing outliers. Numerical tests on synthetic and real datasets illustrate the merits of the proposed algorithms.
Line reversal in baryon exchange processes (1978)

We present differential cross sections at 6 GeV/c for π− and p̄‐induced baryon exchange reactions. These data are used to test line‐reversal symmetry in baryon exchange. Nearly identical triggers were used for each reaction, so that systematic errors in the line reversal tests are small.