gebhart/patrepeval huggingface dataset:
1081: Signal Pathway Profiles Based on Histologic Grade of Human Prostate Cancer Using Reverse Phase Protein Microarrays (2004)

You have accessJournal of UrologyDiscussed Poster, Monday, May 10, 2004, 1:00 - 5:00 pm1 Apr 20041081: Signal Pathway Profiles Based on Histologic Grade of Human Prostate Cancer Using Reverse Phase Protein Microarrays Robert L. Grubb, Valerie S. Calvert, Julia D. Wulfkuhle, Cloud P. Paweletz, John W. Gillespie, W. Marston Linehan, Michael R. Emmert-Buck, Lance A. Liotta, and Emanuel F. Petricoin Robert L. GrubbRobert L. Grubb More articles by this author , Valerie S. CalvertValerie S. Calvert More articles by this author , Julia D. WulfkuhleJulia D. Wulfkuhle More articles by this author , Cloud P. PaweletzCloud P. Paweletz More articles by this author , John W. GillespieJohn W. Gillespie More articles by this author , W. Marston LinehanW. Marston Linehan More articles by this author , Michael R. Emmert-BuckMichael R. Emmert-Buck More articles by this author , Lance A. LiottaLance A. Liotta More articles by this author , and Emanuel F. PetricoinEmanuel F. Petricoin More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(18)38318-6AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "1081: Signal Pathway Profiles Based on Histologic Grade of Human Prostate Cancer Using Reverse Phase Protein Microarrays." The Journal of Urology, 171(4S), p. 285 © 2016 by American Urological AssociationFiguresReferencesRelatedDetails Volume 171Issue 4SApril 2004Page: 285 Advertisement Copyright & Permissions© 2016 by American Urological AssociationMetricsAuthor Information Robert L. Grubb More articles by this author Valerie S. Calvert More articles by this author Julia D. Wulfkuhle More articles by this author Cloud P. Paweletz More articles by this author John W. Gillespie More articles by this author W. Marston Linehan More articles by this author Michael R. Emmert-Buck More articles by this author Lance A. Liotta More articles by this author Emanuel F. Petricoin More articles by this author Expand All Advertisement PDF downloadLoading ...
A Possible Solution for Privacy Preserving Cloud Data Storage (2015)

Despite the economic advantages of cloud data storage, many corporations have not yet migrated to this technology. While corporations in the financial sector cite data security as a reason, corporations in other sectors cite privacy concerns for this reluctance. In this paper, we propose a possible solution for this problem inspired by the HIPAA safe harbor methodology for data anonymization. The proposed technique involves using a hash function that uniquely identifies the data and then splitting data across multiple cloud providers. We propose that such a "Good Enough" approach to privacy-preserving cloud data storage is both technologically feasible and financially advantageous. Following this approach addresses concerns about privacy harms resulting from accidental or deliberate data spills from cloud providers. The "Good Enough" method will enable firms to move their data into the cloud without incurring privacy risks, enabling them to realize the economic advantages provided by the pay-per-use model of cloud data storage.
Strong seismic wave scattering in the low-velocity anomaly associated with subduction of oceanic plate (2014)

Analyses of dense seismic records in Kanto, Japan, revealed distinct pulse broadening and peak delay of high-frequency <it>S</it> waves at central Chiba. These phenomena are observed at frequency range of 1–8 Hz and exist only for ray paths passing through the low-velocity (LV) zone at depth of 20–40 km beneath northwestern Chiba. To obtain a more detailed understanding of these phenomena, we conducted 2-D and 3-D finite difference method simulations of seismic wave propagation using a realistic heterogeneous structure model. Through numerous simulations we demonstrated that strong seismic scattering, due to localized strong small-scale heterogeneities in the LV zone and in the oceanic crust, is a major cause of strong pulse broadening and peak delay of high-frequency <it>S</it> waves. After comparing simulation results with observations, the most preferable small-scale velocity heterogeneity in the LV zone is characterized by a Gaussian power spectral density function (PSDF) with correlation distance <it>a</it> of 1–2 km and rms value <it>&epsiv;</it> = 0.07–0.09, superposed on a background exponential PSDF (<it>a</it> = 3 km, <it>&epsiv;</it> = 0.07). Assuming strong velocity heterogeneities, observed amplitude decay at Chiba is also well explained by strong scattering attenuation in the LV zone. Because the LV zone, which has been reported by seismic tomography studies, is interpreted as being constructed by the dehydration of the subducting oceanic crust of the Philippine Sea Plate, strong small-scale velocity heterogeneity in the LV zone may be related to the random distribution of fluid in this volume.
Sodium handling in patients with well compensated cirrhosis is dependent on the severity of liver disease and portal pressure (2000)

Results suggest that patients with advanced liver disease and low portal pressure handle sodium as well as patients with compensated liver disease and high portal pressure. These results are consistent with the notion that in addition to peripheral vasodilatation and severity of liver disease, the severity of portal hypertension contributes to the abnormalities of sodium retention in cirrhosis.
Glycemic Regulation Using a Programmed Insulin Delivery Device: III. Long-Term Studies on Diabetic Dogs (1979)

Long-term glycemic normalization in diabetic dogs has been achieved using a portable insulin delivery device. Six pancreatectomized male dogs carried the device for periods of 7 ± 2 (range –12) mo. Pulses of insulin were delivered every 90 s into the inferior vena cava through an exteriorized indwelling catheter In the postabsorptive period, insulin was infused at the mean rate of 0.44 ± 0.03 mU/min/kg and glycemia was 93 ± 7 mg/dl, while in the postprandial period insulin was infused for 7 h at the mean rate of 3.10 ± 0.22 mU/min/kg. A standard daily diet was provided, and the resulting glycemic profiles were similar to an age-, sex-, and weight-matched group of six healthy controls. Peripheral insulin levels in the infused diabetic dogs (15 ± 1 μU/ml) were not significantly different from nondiabetic controls in the fasting state and were unresponsive to caloric provocation. However, in the postprandial period of enhanced delivery, insulin levels in the diabetic dogs were two to four times higher than in the controls. Unaccountable episodes of hypo- or hyperglycemia did not occur. Techniques for long-term vascular access were developed such that catheter-related complications, including infection and thrombosis, were not encountered. This study demonstrates the feasibility of long-term glycemic control in unrestrained diabetic animals using a preprogrammed waveform of insulin delivery. Hyperinsulinism accompanies the glycemic normalization when the hormone is delivered peripherally.
An initial assessment of discriminant surface complexity for power law features (1992)

The detection of man-made objects in natural terrain is important in both the targeting and terminal homing phase of modern warfare. The presence of man-made objects in gray-scale images has been successfully detected using a new class of density estimation neural networks to analyze power law signatures. The complex nature of the discriminant surface relating these features has been elucidated using these adaptive mixture networks.
Performance evaluation of Motion-JPEG2000 in comparison with H.264/AVC operated in pure intracoding mode (2004)

Recently, two new international image and video coding standards have been released: the wavelet-based JPEG2000 standard designed basically for compressing still images, and H.264/AVC, the newest generic standard for video coding. As part of the JPEG2000 suite, Motion-JPEG2000 extends JPEG2000 to a range of applications originally associated with a pure video coding standard like H.264/AVC. However, currently little is known about the relative performance of Motion-JPEG2000 and H.264/AVC in terms of coding efficiency on their overlapping domain of target applications requiring the random access of individual pictures. In this paper, we report on a comparative study of the rate-distortion performance of Motion-JPEG2000 and H.264/AVC using a representative set of video material. Our experimental coding results indicate that H.264/AVC performs surprisingly well on individually coded pictures in comparison to the highly sophisticated still image compression technology of JPEG2000. In addition to the rate-distortion analysis, we also provide a brief comparison of the evaluated coding algorithms in terms of complexity and functionality.
Influence of internal structures of hair fiber on hair appearance. III. Generation of light-scattering factors in hair cuticles and the influence on hair shine. (2003)

The effects of thermal treatments on hair fiber induced by blow-drying have been investigated. It was found that the hair shows whitish and powdery appearance after heat drying, especially when dark hair is rapidly dried from a wet condition. For all kinds of hair, the appearance of numerous glittering speckles was confirmed on the cuticle surface by optical microscopic observations. SEM images of hair transverse and longitudinal sections with glittering speckles revealed that the splitting of cuticle layers generated by blow-drying occurred not only at the outermost parts of cuticle cells but also at the inner parts of the cellular interfaces. The release and uptake of moisture through fiber surfaces induces deformation of cuticle cells, probably because of anisotropic swelling or drying of the cells. The cuticles with glittering speckles are found to be fragile and are easily damaged in combination with other mechanical stresses such as combing force. Furthermore, the authors have found an efficient system for both improving hair shine and preventing cuticle damage caused by the blow-drying/combing process.
Quantum probability & related topics : QP-PQ (1991)

On the stochastic limit of quantum chromodynamics, L. Accardi et al flows and imprimitivity systems, L. Accardi and A. Mohari fermion stochastic flows on quantum algebras, D. Applebaum examples of unbounded generators leading to nonconservative minimal semigroups, R.B.V. Bhat and K.B. Sinha on the structure of quantum Markov processes, C. Cecchini diffusion processes in fock space, F. Fagnola on the isomorphism of Poisson space and symmetric fock space, V. Liebscher non-linear master equation and non-crossing cumulants, P. Neu and R. Speicher a general central limit theorem and invariance principle, R. Speicher and W. von Waldenfels.
Cross-Linked Liquid-Crystalline Materials − A Possible Strategy to Ordered Organic Semiconductors (2004)

Ideal materials used in organic electronics should possess both a high order to exhibit high charge carrier mobility and easy processability to achieve low cost production. While single crystals only meet the first property, polymers usually only meet the second. To combine both, it would be desirable to conserve the order of liquid-crystalline phases over a wide temperature range as needed for practical use. In this paper, a synthesis of different liquid-crystalline materials is reported that incorporate both an aromatic heterocyclic core responsible for the semiconductor character and a cross-linkable group to freeze in the liquid-crystal order at a suitable temperature. The liquid-crystalline phases are investigated, and cross-linking experiments are performed. The structure of the prepared films is investigated by X-ray diffraction.
Effects of TAK‐802, a novel acetylcholinesterase inhibitor, and tamsulosin, an α <sub>1</sub> ‐adrenoceptor antagonist, and their synergistic effects on the urodynamic characteristics in a guinea‐pig model of functional bladder outlet obstruction (2005)

These results suggest that TAK-802 and tamsulosin have synergistic effects in increasing the Qmax and voiding efficiency, and TAK-802 does not inhibit the decreasing effect of tamsulosin on urethral resistance. That TAK-802 increased Pves when administered alone implies that monotherapy using an acetylcholinesterase inhibitor should be withheld in patients with voiding dysfunction caused by obvious bladder outlet obstruction with benign prostatic hyperplasia, to avoid disorders of the upper urinary tracts, and it should be used with an alpha1-adrenoceptor antagonist. Whether TAK-802 combined with an alpha1-adrenoceptor antagonist confers additional clinical benefit is not yet known.
Test-Retest-Reliability of Computer-Based Metamorphopsia Measurement in Macular Diseases (2020)

In this study, the test-retest-reliability as one aspect of reliability of metamorphopsia measurements using a computer-based measuring method was determined in patients with macular diseases. Metamorphopsia amplitude, position, and area were quantified using AMD - A Metamorphopsia Detector software (app4eyes GmbH & Co. KG, Germany) in patients with diabetic, myopic, or uveitic macular edema, intermediate or neovascular age-associated macular degeneration, epiretinal membrane, vitelliform maculopathy, Irvine-Gass syndrome, or macular edema due to venous retinal occlusion. The intraclass correlation coefficient (ICC) was calculated in order to determine the repeatability of two repeated measurements and was used as an indicator of the reliability of the measurements. In this study, metamorphopsia measurements were conducted on 36 eyes with macular diseases. Metamorphopsia measurements made using AMD - A Metamorphopsia Detector software were highly reliable and repeatable in patients with maculopathies. The intraclass correlation coefficient of all indices was excellent (0.95 - 0.97). For diseases of the vitreoretinal interface or macular diseases with intra- or subretinal edema, this metamorphopsia measurement represents a supplement for visual function testing in the clinic, as well as in clinical studies.
Analysis of aging effects on the arterial pulse contour using an artificial neural network (2002)

Age correlates both with the prevalence of cardiovascular diseases and with arterial pulse contour changes in healthy adults. If the effect of normal age-related changes can be better elucidated many of the increasingly popular methods of noninvasive pulse contour analysis could be made more reliable. In this paper, the predictability of age in 200 healthy adults is assessed using a radial basis function (RBF) network. The inputs are the complex coefficients of the Fourier transform of a single normalized pulse together with beat length, pulse and mean pressures, the harmonic at peak energy, and gender. Age is the output. Age predictability using different combinations of these components reveals that the first 27 harmonics contain aging information. Use of pulse pressure and harmonic of peak energy improved prediction, while mean pressure, beat length, and gender did not. These results suggest that age-related pulse contour changes in healthy adults are due to pulse pressure rather than absolute pressure, and energy shifts in the frequency distribution rather than changes in heart rate.
Theoretical Researches on Axial-Flow Compressors (Part III)) (1953)

In the previous reports (Part I and II), the calculating methods of various solid vortex type flow patterns were presented. In this report, the expression of efficiency of the solid vortex types is introduced. For the free vortex flow, the manometric efficiency of blade combining rotor and stator becomes maximum for the case of symmetric velocity diagram at the geometrical mean radius. Though the flow conditions which are both solid vortex in the inlet and the outlet of rotor, are two-dimentional in the rotor, back flow occurs at the root of rotor for the multistage axial compressor. But they might be used for pre-rotors. Then the general methods of obtaining velocity profils which are comparatively similar to free vortex by putting the stages which the pressure increase in rotor is not constant at the inlet of compressors suitably, are presented. Finally an example for the outlet solid vortex type is expressed.
An α-d-Galactosyl-binding Lectin from Bandeirae simplicifolia Seeds (1974)

Abstract An α-d-galactosyl binding lectin was purified from Bandeiraea simplicifolia seeds by affinity chromatography. Melibiose was oxidized to the corresponding aldonic acid, and condensed with aminoethyl-Bio-Gel P-300 in the presence of a water-soluble carbodiimide to afford a specific adsorbent which retained B erythrocyte hemagglutinating activity from the seed extract. Elution with galactose-containing buffer displaced the bound lectin which appeared homogeneous by disc gel electrophoresis, pH 4.3, immunoelectrophoresis, gel filtration, and sedimentation analysis. Multiple bands were obtained upon electrophoresis at pH 9.5 and isoelectric focusing. The lectin (mol wt 114,000) is composed of four apparently identical subunits and contains 6.7% by weight carbohydrate (mannose, glucosamine, fucose, and xylose). A metalloprotein, the lectin requires Ca2+ for hemagglutinating activity. Amino acid analysis revealed a high content of acidic and hydroxylic amino acids, only trace amounts of methionine, and one cysteine per subunit. Modification of cysteine with 5,5'-dithiobis(2-nitrobenzoic acid) resulted in complete loss of hemagglutinating activity. Inactivation was partially reversible upon reduction with dithiothreitol. The lectin agglutinates B and AB erythrocytes very strongly, A1 cells weakly, and does not agglutinate A2 or O cells. Polysaccharides and glycoproteins with terminal, nonreducing α-d-galactosyl residues reacted with the lectin to form precipitin bands by Ouchterlony double diffusion, whereas those with terminal β-d-galactosyl residues did not (the galactomannan of Torulopsis gropengiesseri excepted). Polysaccharide precipitating activity of the lectin exhibited an unusually broad pH optimum (6.0 to 11.0), was inhibited by EDTA, destroyed by dialysis of the lectin against acetic acid to remove bound metal, and restored by addition of a divalent metal cation. Glycosides of α-d-galactopyranose were the best inhibitors examined by the hapten inhibition technique. Interestingly, UDP-galactose was shown to inhibit polysaccharide precipitation. Lactose, l-arabinose, d-fucose, d-glucose, and d-mannose were noninhibitory. We suggest that Bandeirae simplicifolia lectin, the first α-d-galactopyranosyl binding lectin (anti-B lectin) to be purified and characterized, will be valuable not only as a serological reagent, but in studies of polysaccharides, glycoproteins, and cell membrane structure.
Control of Millipedes in Greenhouse Soil (1961)

Journal Article Control of Millipedes in Greenhouse Soil Get access T. J. Henneberry, T. J. Henneberry Entomology Research Division, Agric. Res. Serv., U.S.D.A. Search for other works by this author on: Oxford Academic PubMed Google Scholar E. A. Taylor E. A. Taylor Entomology Research Division, Agric. Res. Serv., U.S.D.A. Search for other works by this author on: Oxford Academic PubMed Google Scholar Journal of Economic Entomology, Volume 54, Issue 1, 1 February 1961, Pages 197–198, https://doi.org/10.1093/jee/54.1.197 Published: 01 February 1961 Article history Accepted: 02 September 1960 Published: 01 February 1961
RAPD and ISSR markers of fertility restoring gene for aegilops kotschyi cytoplasmic male sterility in wheat (2002)

LK783 was found to be a good fertility restorer for K-type male sterility of wheat(Triticum aestivum L.).RAPD and ISSR( nter-simple sequence repeat polymorphism) markers were employed to map the major restoring gene in LK783.Maintainer and restorer DNA pools were established using the extreme sterile RAPD primers and 33 ISSR primers were used for screening polymorphisms between the two pools,and amplification bands using a RAPD primer fo OPK18 and an ISSR primer of UBC-845_(800) were linked to the restoring genein LK783.The distance between the restoring gene and OPK18_(450) was (15.07+-6.28)cM(centiMorgan),with the distance between the restoring gene and UBC-845_(800) being(8.20+-4.85)cM.The marker of UBC845_(800) was located on chromosome 1BS by amplifying nulli-tetrasomics and 1B ditelosomics of Chinese Spring with the primer of UBC_845,indicating that the restoring gene in LK783 was located on 1BS.The breeding for new fertility restorer lines of K-type cytoplasmic male sterility of wheat would be facilitated by using the two markers.
Design of PEBB based power electronics systems (2006)

The standardization of power electronics that come with the power electronics building blocks (PEBB) is expected to expand the use of power electronics through reduced costs and higher reliability. Part of the cost reduction comes from the simplification in the design process that is obtained by using standard modules. This paper analyzes the PEBB based design process and discusses some ideas about the design of power converters based on power modules and appropriate tools for the design
Kronenthioetherkomplexe des Blei(II), Zink(II) und Cadmium (II) und Cadmium(II). Die Kristallstrukturen von [PbL<sub>2</sub>(ClO<sub>4</sub>)<sub>2</sub>] und [ZnL<sub>2</sub>](ClO<sub>4</sub>)<sub>2</sub> · CH<sub>3</sub>CN (L = 1,4,7 ‐ Trithiacyclononan) (1989)

Abstract Die Umsetzung von 1,4,7‐Trithiacyclononan (L) mit den Perchloratsalzen des Blei(II) und Zink(II) in CH 3 CN (2:1) führt zu den farblosen Salzen [PbL 2 (ClO 4 ) 2 ] und [ZnL 2 ](ClO 4 ) 2 · CH 3 CN. Die Kristallstrukturen wurden bestimmt: Das Pb II ‐Ion ist von 6 Thioether‐schwefelatomen (mittlerer Abstand PbS 3,076 Å) sowie zwei O‐Atomen von jeweils einem ClO 4 ‐Anion (einzähnig koordiniertes ClO 4 − ) umgeben, wodurch ein verzerrt quadratisch antiprismatisches Koordinationspolyeder am Pb II erzeugt wird. Im [ZnL 2 ](ClO 4 ) 2 · CH 3 CN ist das Zn II oktaedrisch von sechs Schwefelatomen umgeben (mittlerer Abstand ZnS = 2,494 Å); die ClO 4 − ‐Anionen sind nicht koordiniert. Für [CdL 2 ](ClO 4 ) 2 · H 2 O, das ebenfalls dargestellt wurde, wird eine analoge Struktur vorgeschlagen.
Digital bilinear feedback for low‐power double‐sampling sigma–delta modulators (2014)

A novel double‐sampling (DS) technique for use in sigma–delta modulators (ΣΔMs) is presented. The proposed technique uses a digital bilinear filter in the feedback path of the modulator loop. The bilinear filter suppresses the quantisation noise folding (QNF) that results from the DS path mismatch. Unlike other solutions for the QNF, the digital implementation of this filter allows the sharing of the input sampling capacitor with the feedback sampling capacitor without any additional analogue gain stages. This way, the power consumption in the input signal buffer can be greatly reduced, because it benefits from the nullator effect at the input of the ΣΔM loop, and hence the current needed to drive the shared sampling capacitor is drastically reduced. Moreover, the proposed DS technique is also suitable for a single‐ended circuit implementation of DS.