gebhart/patrepeval huggingface dataset:
Antimicrobial Performance of Tri- and Tetrachloro-4-(Methylsulfonyl) Pyridines as Industrial Preservatives (1967)

Tests show that trichloro- and tetrachloro-4-(methylsulfonyl) pyridines have a wide spectrum of activity against microorganisms causing deterioration in industrial systems. They are particularly active as fungistats and are more effective against gram-positive than against gram-negative bacteria. Their fungistatic activity and persistence have led to outstanding performance as mildewcides in exterior paints. In addition, we report the performance of these compounds as preservatives in the following products: asphalt, calking compositions, joint cements, paper, plastics, soluble oils (cutting fluid emulsions), and textiles.
Immunostaining of PRAD1/cyclin D1 protein as a marker for the diagnosis of mantle cell lymphoma. (1997)

The overexpression of PRAD1/cyclin D1 gene activated by the 11q13 translocation and its molecular counterpart BCL-1 rearrangement is frequently associated with mantle cell lymphomas (MCLs). Recently, we produced a monoclonal antibody, 5D4, against the PRAD1/cyclin D1 product, and demonstrated that the positive nuclear staining by this antibody correlates with PRAD1/cyclin D1 mRNA overexpression in MCLs. In the present study, we have immunohistochemically examined the cyclin D1 protein in a large series of 315 malignant lymphomas including 39 MCLs on paraffin sections. The nuclear positive pattern was found in 35 (90%) of 39 MCLs with an exceptional case of immunocytoma among the B-cell lymphomas examined. In the other cases, the positivity was absent or appeared to lie within the cytoplasm without nuclear staining. We therefore propose that the immunolocalization of cyclin D1 protein is an essential marker for the definite diagnosis of MCL.
ChemInform Abstract: Synthesis of a Hexaalkynylhexaphenylbenzene. (1992)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Grain-boundary space-charge conduction (1986)

Recent research on silicon grain boundaries has confirmed the typical features known from earlier work on grain boundaries in germanium and III-V compound semiconductors. However, there is less clarity with respect to the role of the ‘‘dangling bonds’’ when testing for electrical activity. In silicon a pronounced double barrier with its space-charge layer and a low leakage current rarely forms. Here the Cottrell atmospheres in conjunction with impurity complexes such as SiO, SiO2, and SiO4 can strongly influence the electrical properties in a material with an exceptionally high self-diffusivity. Conditions for the measurability of the longitudinal impurity band-type conduction through space-charge layers in silicon grain boundaries are outlined. It is concluded that in those cases where electrical activity is measured, the conduction parallel to the grain-boundary plane should be apparent for pure material and at low temperature. Experiments are proposed to further our understanding of the properties of grain boundaries in silicon.
Genotype combinations of plasminogen activator inhibitor-1 and angiotensin-converting enzyme genes and risk for early onset of coronary heart disease (2006)

The co-existence of the 4G/5G polymorphism of the plasminogen activator inhibitor type 1 gene and the I/D polymorphism of the angiotensin-converting enzyme gene increases the risk for early onset of coronary heart disease in this population.
A High Polymerization of Ethylene Oxide with Metal Phosphate Catalysts (1963)

各種金属リン酸塩触媒によるエチレンオキシドの高重合反応について研究を行なった。チダンおよびジルコニウムのリン酸塩が特に高活性であった。ジルコニウムリン酸塩を触媒とした場合について反応条件を変えて詳細に検討した。触媒の焼成温度を上げると重合率は低下するが,900℃以上の焼成物を用いると生成重合物の分子量はいちじるしく増大した。また,重合率は反応時間のほぼ0.5乗に比例するが,生成重合物の分子量は反応時間によらない。反応温度の影響について検討した結果,見掛けの活性化エネルギーはほぼ17kcal/molである。これらの事実より反応の律速段階は触媒表面に生成したポリマー層をモノマーが拡散する過程であると考えた。また,重合率が触媒の酸性度に比例している点から,本重合反応は固体酸触媒によるカチオン連鎖重合反応であると推論した。
ChemInform Abstract: Synthetic Studies on Bicyclomycin and Its Analogues. Part 1. Synthesis of Substituted 2‐Oxa‐8,10‐diazabicyclo(4.2.2.)decanes. (1989)

Abstract The alkylated and deprotected mono imino ether (III) undergoes oxidation and cyclization to give the title compound analogue (IV).
Subcutaneous Recombinant Human Erythropoietin for the Treatment of Anemia in Myelodysplastic Syndromes (1993)

Recombinant human erythropoietin (rhEPO) was administered subcutaneously to 13 anemic (Hb < 10 g/dl) patients with myelodysplasia (MDS). rhEPO was given 3 times a week at doses of 75-250 U/kg body weight, over a maximum period of 24 weeks. Five patients (38%) showed a response to rhEPO treatment. rhEPO was well tolerated and without relevant side effects throughout the study. All responding patients had low but detectable pretreatment circulating erythroid progenitor cells (BFU-E) and the response to rhEPO was associated with a significant increase in BFU-E (p < 0.01); concentrations of serum transferrin receptor (TfR) also consistently rose in all responding patients. Baseline erythropoietin (EPO) concentrations did not significantly differ between responders and nonresponders, although 4 out of the 5 responders had relatively low levels of EPO. In conclusion, subcutaneous rhEPO administration appears to be an effective treatment of anemia in a substantial subset of patients with MDS. Relatively low baseline EPO concentrations, detectable pretreatment circulating BFU-E and an early increase in the serum concentrations of TfR seem to be criteria for predicting response to rhEPO in patients with MDS.
Determination of the magnetic order and the crystal symmetry in the multiferroic ground state of Ba<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:msub><mml:mrow/><mml:mn>2</mml:mn></mml:msub></mml:math>CoGe<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:msub><mml:mrow/><mml:mn>2</mml:mn></mml:msub></mml:math>O<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:msub><mml:mrow/><mml:mn>7</mml:mn></mml:msub></mml:math> (2012)

Detailed structural investigation of Ba${}_{2}$CoGe${}_{2}$O${}_{7}$ was performed in its low-temperature multiferroic state combining neutron diffraction with magnetization measurements and the optical study of lattice vibrations on single crystals. The crystal structure above (10.4 K) and the crystal and magnetic structures below (2.2 K) the antiferromagnetic transition temperature of ${T}_{N}$ $=$ 6.7 K were determined using neutron diffraction. The tetragonal space group (SG) $P$-42${}_{1}m$, corresponding to the average structure at room temperature, was found to also describe the structure at low temperatures well. Neutron diffraction data and infrared phonon mode analysis imply no structural phase transition down to 2.2 K. Orthorhombic polar SG Cmm2 is proposed as a true crystal structure. Below ${T}_{N}$, the spins of the Co${}^{2+}$ ions form a square-lattice N\'eel order within the ($a$,$b$) plane, while their alignment is ferromagnetic along the $c$ axis. The magnitude of the ordered moment, fully lying within the ($a$,$b$) plane, is found to be 2.9(1) ${\ensuremath{\mu}}_{B}$/Co${}^{2+}$ and the easy axis of the sublattice magnetizations corresponds to the [110] direction. A noncollinear spin structure due to small canting is allowed.
Protein concentration of lymph and interstitial fluid in the rat tail (1984)

Lymph was collected from tail lymphatics of anesthetized rats, subcutaneous interstitial fluid was obtained by implanting nylon wicks, and tendon interstitial fluid was obtained by centrifugation of pieces of tendon. Spontaneous lymph flow rates averaged 70 nl X min-1 X g skin-1. Protein concentrations and colloid osmotic pressures of sampled fluids differed significantly. Tail lymph had the highest protein concentration relative to plasma [lymph-to-plasma ratio 0.71 +/- 0.03 (SE) n = 10], followed by wick fluid (0.62 +/- 0.02, n = 9), with tendon fluid lowest (0.50 +/- 0.03, n = 10). Albumin and immunoglobulin G (IgG) concentrations in samples of tail skin and tendon were assayed by rocket immunoelectrophoresis. Comparison of their distribution volumes at lymph or tendon fluid concentrations, respectively, with interstitial fluid volumes measured as 2-h 51Cr-ethylenediaminetetraacetic acid space minus 5-min 125I-albumin space indicated that 50-60% of the interstitial volume in these tissues is not available for distribution of albumin or IgG. Low lymph flow and high interstitial protein content of rat tail indicate a slow turnover of interstitial protein. This suggests that interstitial washout of protein plays a role in limiting edema only after a sustained or chronic increase in fluid filtration.
Synthesis of Static and Dynamic Multiple-Input Translinear Element Networks (2004)

In this paper, we discuss the process of synthesizing static and dynamic multiple-input translinear element (MITE) networks systematically from high-level descriptions given in the time domain, in terms of static polynomial constraints and algebraic differential equations. We provide several examples, illustrating the process for both static and dynamic system constraints. Although our examples will all involve MITE networks, the early steps of the synthesis process are equally applicable to the synthesis of static and dynamic translinear-loop circuits.
Hardware Implementation Of Stack-Based Replacement Algorithms (2008)

Block replacement algorithms to increase hit ratio have been extensively used in cache memory management. Among basic replacement schemes, LRU and FIFO have been shown to be effective replacement algorithms in terms of hit rates. In this paper, we introduce a flexible stack-based circuit which can be employed in hardware implementation of both LRU and FIFO policies. We propose a simple and efficient architecture such that stack-based replacement algorithms can be implemented without the drawbacks of the traditional architectures. The stack is modular and hence, a set of stack rows can be cascaded depending on the number of blocks in each cache set. Our circuit can be implemented in conjunction with the cache controller and static/dynamic memories to form a cache system. Experimental results exhibit that our proposed circuit provides an average value of 26% improvement in storage bits and its maximum operating frequency is increased by a factor of two
Microfilament depletion and circumvention of multiple drug resistance by sphinxolides. (1997)

Sphinxolides, a newly described family of cytotoxins from the New Caledonian sponge Neosiphonia superstes, bear structural resemblance to scytophycins. We now demonstrate that the cytotoxicity of sphinxolides is associated with cell cycle arrest in G2-M and induction of apoptosis. Like scytophycins and cytochalasins, sphinxolides caused rapid loss of microfilaments in cultured cells, without affecting microtubule organization. Microfilament reassembly was very slow after removal of the sphinxolide, consistent with the slow recovery of cellular proliferation. Sphinxolides potently inhibited actin polymerization in vitro and the microfilament-dependent ATPase activity of purified actomyosin, indicating a direct effect on actin. Importantly, sphinxolides were equally cytotoxic toward MCF-7 human breast carcinoma cells and a subline which overexpresses P-glycoprotein (MCF-7/ADR). Similarly, overexpression of the multidrug resistance-associated protein MRP by HL-60 cells did not confer resistance to the sphinxolides. These studies demonstrate that sphinxolides are potent new antimicrofilament compounds that circumvent multidrug resistance mediated by overexpression of either P-glycoprotein or MRP. Therefore, these agents may be useful in the treatment of drug-resistant tumors.
INFLUENCE OF ADDITIVES ON FUNCTIONAL AND NUTRITIONAL QUALITY CHARACTERISTICS OF BLACK GRAM FLOUR INCORPORATED PASTA (2011)

ABSTRACT To improve the functional and nutritional profile of pasta, the present study aims to develop black gram pasta using a blend of 70% Triticum durum semolina and 30% black gram flour; and it also aims to understand the influence of additives on the quality of pasta. Black gram pasta samples were evaluated for cooking quality, color, texture, protein profile, pasting characteristics, in vitro starch hydrolysis, microstructure and sensory quality. Results indicated protein content improvement for black gram substituted durum pasta (BGDP30) with 3% gluten and 0.5% hydroxypropyl methylcellose (HPMC); black gram substituted durum pasta with HMPC(BGDPC)(16.49%) from that of 30% BGDP30 (14.37%) and control (12.37%). The lightness value of BGDPC (51.66) was closer to control (50.88). The texture was improved from 1.01 N to 1.53 N, but it was still lesser than control (2.12N). The overall quality score for BGDPC (25.17) was better than control (23.96). The study indicated that with combination of gluten and HPMC, more desirable black gram pasta could be produced. PRACTICAL APPLICATION Pasta products rank as number two staple food and it is consumed worldwide. Black gram is known to be hypoglycemic agent and a good source of protein. The present manuscript demonstrated that the use of black gram flour (BGF) along with additives would improve the pasta product functional and nutritional quality. The present study indicates that the use of BGF along with additives will improve the nutritional quality of the pasta in terms of antioxidant and hypoglycemic activity. The outcome of the present study will have greater potential for pasta industries to develop healthier pasta products using BGF.
THE INLAND <i>CHAETOCEROS</i> (BACILLARIOPHYCEAE) SPECIES OF NORTH AMERICA<sup>1</sup> (1986)

ABSTRACT Five taxa of Chaetoceros occur in inland waters of North America. These most commonly occur in waters with elevated total dissolved solids in arid regions of the western United States and Canada . Chaetoceros amanita Cleve‐Euler is characterized by consistently forming relatively long chains of cells and having very spinose primary resting spore valves . Chaetoceros elmorei Boyer also forms long chains of cells which are connected by evident valvar processes; spores are nearly always smooth . Chaetoceros muelleri Lemm. may form short chains with processes between sibling valves, but also produces solitary cells lacking processes . Chaetoceros muelleri var . subsalsum (Lemm.)Johansen et Rushforth is similar to the nominate but never produces cells with Processes. Both of the C. muelleri varieties produce spores with smooth primary valves . Chaetoceros simplex Ostenfeld is characterized by a noncolonial habit, cells lacking processes and the production of resting spores with warty to some what spinose primary valves .
Oxidative stress--induced single-strand breaks in chromosomal telomeres of human retinal pigment epithelial cells in vitro. (2001)

RPE340 cells in vitro grown in chronic hyperoxia exhibited evidence of DNA damage with accelerated telomeric shortening via an increased accumulation of single-strand breaks in telomeric DNA. These changes could provide insight into aging of RPE cells by oxidative DNA damage.
Enhancing Effect of Feces on Isolation of Salmonellae From Selenite Broth (1964)

The addition of feces to selenite broth significantly enhanced the ability of this medium to select for salmonellae in an environment initially containing overwhelming numbers of coliform bacteria. Either heat-sterilized or Seitz-filtered feces produced this effect. In most experiments, the selectivity of selenite broth was unaffected by unsterile feces. Human blood and plasma markedly reduced selenite efficiency. In a base medium supporting both coliform and Shigella growth, heat-sterilized feces imposed a measure of selectivity for Shigella.
A parametric study of location effects on the sidebands of Helmholtz resonators using boundary element analysis (2002)

An important noise source used to tune automotive interior sound levels and quality is the sound which radiates from the open end of the engine induction system—induction noise. Understanding this source and its tuning can be vital to produce the customer-desired sound inside the vehicle. The most traditional method to attenuate (or tune) induction noise is through the addition of passive devices, the most common of which is the Helmholtz resonator. An unfortunate side effect to such a device is that narrow bands of frequencies higher and lower than the bandwidth of the resonator, called sidebands, tend to be amplified by the device. The subject of this study is to qualify the effect of changing resonator location on these sidebands. This is studied by determining the system frequency response to a white noise input by performing boundary element analysis on a simplified air induction system. The location of the device is varied, and the magnitude and frequency shift of the sidebands are studied. Experimental validation is also provided for select models.
Anomeric information obtained from a series of synthetic trisaccharides using energy resolved mass spectra (2007)

The majority of structural investigations of oligosaccharides based on mass spectrometry use naturally occurring oligosaccharides, which do not allow extracting any common feature associated with anomeric structures and linkage positions. In order to address the issue to find such characteristics possibly contained in oligosaccharide structure, a synthetic combinatorial trisaccharide library was analyzed. The trisaccharides used in the analysis consisted of L-fucose, D-galactose and D-glucose, in which individual glycosidic linkages existed in either alpha- or beta-anomers. The analysis of energy-resolved mass spectra (ERMS) and the scattered plot analysis of some parameters obtained from ERMS for a series of trisaccharides revealed that lower activation energy was required for the dissociation of alpha-glycosides of these sugars compared to those of the corresponding beta-anomers. It is suggested that this finding may be useful in structural analysis of natural oligosaccharides.
Residual effects of TMOF–Bti formulations against 1st instar Aedes aegypti Linnaeus larvae outside laboratory (2012)

From the results it can be concluded that the TMOF-Bti formulations can be utilized in dengue vector control.
Separation andStructure ofComponents ofNuclear Polyhedrosis VirusoftheSilkworm (1971)

Morphology ofstructural componentsofnuclear polyhedrosis virus(NPV) particles ofthesilkworm (Bombyx moriLinne) was studied byelectron microscope using negative staining. NPV particles isolated frompolyhedra couldbeseparated intofive structural componentsbycentrifugation insucrosedensity gradients. The lowest band(bandI)was foundtoconsist ofthick rod-shaped particles (330by 80nm)withknobbysurfaces andwithoccasional protrusion atone end.The second bandfromthebottom(bandII) was showntoconsist mainly ofslender rodshaped particles (360by60nm),inwhichinternal structures werevisible asa dense mass.Regular striations were also seenon thesurface ofthese particles. Bytreatmentwithmercaptoethanol, these particles weredrastically damaged, andinsome casestheinternal substances werepartially released, producing emptyinner membranes ofvarious degrees ofdisintegration. InbandsIIIandIV,bothemptysphericalandemptyrod-shaped membranes were present. BandIIIwas richinempty spherical membranes which were showntobetheoutermembranesofthickrodshaped particles. Theemptyrod-shaped membranes, theinnermembranes, were mainly located inbandIVandhavecrossstriations on thesurface. Itisremarkable thattheuppermostband(bandV)consisted purely ofsmallspherical particles, somewhat heterogeneous insize andshape(around 20to25nm indiameter), indicating theparticles tobethedegradation product ofthevirusparticles. Similar particles could also beobserved within theemptyinner membranes.
Zooplankton abundance during Dalniye Zelentsy cruise 90BY8180 (2000)

Matishov, Gennady G; Makarevich, Pavel R; Timofeev, Sergey F; Kuznetsov, Leonid L; Druzhkov, Nikolay V; Larionov, Viktor V; Golubev, Valery A; Zuyev, Aleksey N; Denisov, V I; Adrov, Nikolai M; Iliyn, G; Kuznetsov, A; Denisenko, Stanislav G; Savinov, Vladimir M; Shavikyn, A; Smolyar, I V; Levitus, Sydney; O'Brien, Todd; Baranova, Olga K (2000): Zooplankton abundance during Dalniye Zelentsy cruise 90BY8180 [dataset]. Murmansk Marine Biological Institute, PANGAEA, https://doi.org/10.1594/PANGAEA.827027, In supplement to: Matishov, GG et al. (2000): Biological Atlas of the Arctic Seas 2000: Plankton of the Barents and Kara Seas (in english). International Ocean Atlas Series, Murmansk Marine Biological Institute, Russia; Ocean Climate Laboratory, NODC/NOAA, USA, 2, 348 pp, hdl:10013/epic.42580.d025
Stabilization of systems with asynchronous sensors and controllers (2016)

We study the stabilization of networked control systems with asynchronous sensors and controllers. Offsets between the sensor and controller clocks are unknown and modeled as parametric uncertainty. First we consider multi-input linear systems and provide a sufficient condition for the existence of linear time-invariant controllers that are capable of stabilizing the closed-loop system for every clock offset in a given range of admissible values. For first-order systems, we next obtain the maximum length of the offset range for which the system can be stabilized by a single controller. Finally, this bound is compared with the offset bounds that would be allowed if we restricted our attention to static output feedback controllers.
Suggestion of a method for predicting different response characteristics including major cracks induced by blast loading in concrete slabs using machine learning (2009)

The paper suggests a technique for predicting major cracks and other response characteristics of different concrete slabs under blast loadings using the methods of supervised statistical machine learning. To construct the input-output dataset for the learning stage, data from finite number of experiments with different spherical and cylindrical charges have been used. The parameters of the covariance function have been optimized maximizing the log of the marginal likelihood for the experimental results. The obtained parameters are then used in the inference stage when the behaviour of the concrete slab is statistically predicted for new blast cases not considered in the experiments. The results demonstrate that by conducting only a finite number of experiments and by applying the proposed machine learning techniques, one can predict the responses of the concrete slabs for infinite number of combinations of the parameters of the experiment. This can significantly decrease the number of experiments required for constructing reliable mechanical models. The proposed method provides predictions even in the case when there are only a few experimental results. The uncertainty will be high in this case of few experiments; however the uncertainty will be significantly reduced once new experimental results are provided to the proposed Bayesian predictive model.
Fundamentals of Hydrogels and Gelation (1986)

Abstract A discussion of the properties of that class of materials known as ‘hydrogels’ must make particular reference to (i) a working definition of what is meant by a ‘gel’, (ii) the manner in which this relates to the underlying macromolecular structure, and (iii) how these properties are affected by the presence of water within the macromolecular network. The first point is answered by providing an operational definition of a gel, which depends on the mechanical response of the material to oscillatory shear. This type of behaviour is shown to be quantitatively related to the degree of connectivity of the network. The chemical aspects of the problem address the relationship between this and the degree of reaction achieved by those chemical or physical features responsible for crosslinking. Finally, the swelling properties of such materials are discussed, and how these are complicated by the non‐ideal thermodynamic properties of the solvent water.