gebhart/patrepeval huggingface dataset:
Some molecular properties of NAD(P)H dehydrogenase from rat liver (1979)

NAD(P)H dehydrogenase (EC 1.6.99.2) purified from rat liver cytosol revealed three discrete bands, of mol.wts. about 27000, 18000 and 9000, when subjected to polyacrylamidegel electrophoresis in the presence of sodium dodecyl sulphate. Elution of the bands from the gel and individual re-electrophoresis on separate gels showed that the 27000-mol.wt. band yielded three bands similar to those obtained with the intact enzyme, whereas the 18000-mol.wt. band retained its characteristic mobility. Amino acid analysis of native enzyme and protein extracted from each of the three bands from sodium dodecyl sulphate/polyacrylamide gels suggests that the native enzyme is composed of two subunits and that each subunit consists of two dissimilar non-covalently bound polypeptides, so that altogether the enzyme is composed of four polypeptides, two of mol.wt. 18000 and two of mol.wt. 9000. NAD(P)H dehydrogenase was active over a wide pH range with no sharp optimum. The same K(m) value for NADH but different values for V(max.) were obtained for the enzyme purified from Sprague-Dawley and Wistar rats. In immunodiffusion, however, the enzymes from the two rat strains showed a reaction of complete identity. NAD(P)H dehydrogenase was effectively inhibited by thiol-blocking reagents, indicating that the activity is dependent on free thiol group(s). By amino acid analysis six cysteine residues were found per mol of enzyme. Guanidino-group- and amino-group-selective reagents had only moderate inactivating effects on the enzyme activity.
Systems biology approaches to understand the effects of nutrition and promote health (2016)

Within the last years the implementation of systems biology in nutritional research has emerged as a powerful tool to understand the mechanisms by which dietary components promote health and prevent disease as well as to identify the biologically active molecules involved in such effects. Systems biology, by combining several '-omics' disciplines (mainly genomics/transcriptomics, proteomics and metabolomics), creates large data sets that upon computational integration provide in silico predictive networks that allow a more extensive analysis of the individual response to a nutritional intervention and provide a more global comprehensive understanding of how diet may influence health and disease. Numerous studies have demonstrated that diet and particularly bioactive food components play a pivotal role in helping to counteract environmental-related oxidative damage. Oxidative stress is considered to be strongly implicated in ageing and the pathophysiology of numerous diseases including neurodegenerative disease, cancers, metabolic disorders and cardiovascular diseases. In the following review we will provide insights into the role of systems biology in nutritional research and focus on transcriptomic, proteomic and metabolomics studies that have demonstrated the ability of functional foods and their bioactive components to fight against oxidative damage and contribute to health benefits.
Cooling solutions for processor Infrared Thermography (2010)

Temperature is a key parameter due to its impact on timing, energy, and reliability. A setup to measure temperature in runtime with high spatial and temporal resolution would help to study the thermal behavior of processors. Currently, Infrared Thermography infrastructures has been developed to measure the temperature in real-time. Since the infrared opaque metal heat sinks need to be replaced with an infrared transparent heat sink in these setups, oil based cooling solutions have been proposed. However, oil is not a representative of a metal heat sink because measurement with oil based cooling can change the thermal behavior of the processor. In this paper, we discuss a representative oil based cooling solution, and show that it has the same thermal response as a metal heat sink.
Dansyl chloride labelling of stratum corneum: its rapid extraction from skin can predict skin irritation due to surfactants and cleansing products (1994)

The irritation potential of surfactants and body cleansing products was determined by evaluating the removal of dansyl chloride from the skin. Dilute solutions (2% active ingredient, w/v) of surfactants and soap extract fluorescence from the skin within 30 min. This is probably a physicochemical effect as it is too rapid to be due to a modification of epidermal cell turnover rate. Such an extraction of the fluorescent dye occurs without any clinical sign of irritation. However, it may represent an early phase of the skin irritation process, because it is related to the ranking of irritant products as determined by other assessment methods.
Low-Temperature Al<sub>2</sub>O<sub>3</sub> Atomic Layer Deposition (2004)

Al2O3 films were deposited by atomic layer deposition (ALD) at temperatures as low as 33 °C in a viscous-flow reactor using alternating exposures of Al(CH3)3 (trimethylaluminum [TMA]) and H2O. Low-temperature Al2O3 ALD films have the potential to coat thermally fragile substrates such as organic, polymeric, or biological materials. The properties of low-temperature Al2O3 ALD films were investigated versus growth temperature by depositing films on Si(100) substrates and quartz crystal microbalance (QCM) sensors. Al2O3 film thicknesses, growth rates, densities, and optical properties were determined using surface profilometry, atomic force microscopy (AFM), QCM, and spectroscopic ellipsometry. Al2O3 film densities were lower at lower deposition temperatures. Al2O3 ALD film densities were 3.0 g/cm3 at 177 °C and 2.5 g/cm3 at 33 °C. AFM images showed that Al2O3 ALD films grown at low temperatures were very smooth with a root-mean-squared (RMS) roughness of only 4 ± 1 Å. Current−voltage and capacitance−voltage measurements showed good electrical properties of the low-temperature Al2O3 ALD films. Elemental analysis of the films using forward recoil spectrometry revealed hydrogen concentrations that increased with decreasing growth temperature. No other elements were observed by Rutherford backscattering spectrometry except the parent aluminum and oxygen concentrations. Low-temperature Al2O3 ALD at 58 °C was demonstrated for the first time on a poly(ethylene terephthalate) (PET) polymeric substrate. Al2O3 ALD coatings on PET bottles resulted in reduced CO2 gas permeabilities.
Neural Networks Training Based on Sequential Extended Kalman Filtering for Single Trial EEG Classification (2010)

The nonstationary nature of the brain signals provides a rather unstable input resulting in uncertainty and complexity in the control. Intelligent processing algorithms adapted to the task are a prerequisite for reliable BCI applications. This work presents a novel intelligent processing strategy for the realization of an effective BCI which has the capability to improved classification accuracy and communication rate as well. A neural networks training based on sequential extended Kalman filtering analysis for classification of extracted EEG signal is proposed. A statistically significant improvement was achieved with respect to the rates provided by raw data.
Fuzzy Green: A Modified TCP Equation-Based Active Queue Management Using Fuzzy Logic Approach (2006)

Congestion control provides quality of service over the best effort networks. Congestion occurred when arrival rate to a router is greater than its departure rate. In this paper, using fuzzy logic approach, we have proposed a modified TCP equation-based active queue management mechanism which is based on traditional GREEN algorithm. Here we present our fuzzy GREEN controller which is expected to act as a congestion controller in the routers. We have simulated our fuzzy method both with and without background Pareto traffic and the results show the superiority of our fuzzy method compared to the non-fuzzy one in both long-lived as well as short-lived connections. Key words:
Nonlinear control of soliton pulse delay with asymmetric dual-core photonic crystal fibers (2009)

Dual-core photonic crystal fiber nonlinear couplers permit the achievement of distortion-free power-controlled delay of picosecond pulses. The stable control of pulse time delay is achievable by means of resonance soliton solutions.
Shock induced amorphization as the onset of spall (2005)

Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter Facebook Reddit LinkedIn Tools Icon Tools Reprints and Permissions Cite Icon Cite Search Site Citation Yinon Ashkenazy, Robert S. Averback; Shock induced amorphization as the onset of spall. Appl. Phys. Lett. 31 January 2005; 86 (5): 051907. https://doi.org/10.1063/1.1861974 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAIP Publishing PortfolioApplied Physics Letters Search Advanced Search |Citation Search
<i>Daphnia magna</i> can tolerate short‐term starvation without major changes in lipid metabolism (2005)

Daphnia magna is a common crustacean that is adapted to brief spells of fasting. Lipids are naturally a major component of their diet and are stored as energy reserves. However, there has been some controversy in the literature on the extent to which dietary lipids are used directly for complex lipid formation in Daphnia. We examined lipid metabolism in D. magna by labeling the animals using [1-14C]acetate and then followed the turnover of radiolabeled lipids during a pulse chase. Daphnia were either fed or maintained without food during the chase period. The decrease in radioactivity during the chase was relatively unaffected by feeding, although there were some differences in the distribution of radioactivity between lipid classes or individual FA. The polar lipids, which were four times better labeled than nonpolar lipids, contained the most radioactivity in the zwitterionic phosphoglycerides, PE and PC. Under the experimental conditions, the turnover of the polar membrane lipids was unaffected by feeding. Within nonpolar lipids, TAG accounted for up to about 80% of the label, followed by DAG. Overall, our data show that D. magna is capable of high rates of lipid radiolabeling de novo and, in addition, is able to use--and indeed may be dependent on--some dietary components such as the PUFA linoleate and alpha-linolenate. The results also clearly show that Daphnia is able to tolerate brief spells of fasting (24 h) with very little change to its lipid metabolism.
Detection and sizing of surface flaws with a squid-based eddy-current probe (1987)

In a new approach to eddy current detection and sizing of surface-breaking flaws, we have coupled a conventional reflection probe to a superconducting quantum interference device (SQUID) to produce an eddy current probe with increased sensitivity and signal to noise ratio. The reflection probe consists of an air-core excitation coil surrounding two counterwound ferite-core pickup coils connected in series. A room-temperature probe is inductively coupled to a SQUID, which operates in a liquid helium bath. The new probe was used to obtain flaw signals from a number of electrical-discharge machined slots in aluminum alloy 6061. Results indicated that by scanning the probe along the length of the flaw, the length could be determined from the extent of the flaw signal. The peak amplitude of the flaw signal was found to be proportional to the cross-sectional area of the flaw. Empirical calibration curves relating these quantities were used to invert successfully the experimental data obtained for the RDM slots.
Erratum: Magnetic Response of Mesoscopic Superconducting Rings with Two Order Parameters [Phys. Rev. Lett.<b>97</b>, 237002 (2006)] (2007)

Received 24 April 2007DOI:https://doi.org/10.1103/PhysRevLett.98.209902©2007 American Physical Society
Attempted Diastereoselective Preparation and Chiroptical Properties of (2S)-1-(3-Mercapto-2-Methyl-1-Oxopropyl)-L-Proline (Captopril) and Some Congeners (1989)

CD and 13C-NMRstudy of the eonformational properties of (2S) -1-(3-mereapto-2-methy l-l-oxopropyl) -L-proline (eaptopril, 1), and its congeners 2-5, 8, 9 is reported.13C-NMRdata (in DMSO--d6) reveal an E/Z (cis!trans) ratio of ea.(15-30) : (70~85) for the N-aeyl-prolines 1, 5, 10, and for N-aeetyl-L-proline.CD data indicate praetieally identical conformations for the ring systems of 8 and 9. Attempted diastereoselective cyclization of the sodium salt of 7 or the free thioacid into 8 and 9 resulted in low chemical yields (-30%) and low diastereoselectivity, favouring formation of the wrong-diastereomer 9 in small excess (-20%).
New class of control laws for robotic manipulators Part 1. Non–adaptive case (1988)

A new class of exponentially stabilizing control laws for joint level control of robot arms is introduced. It has recently been recognized that the non-linear dynamics associated with robotic manipulators have certain inherent passivity properties. More specifically, the derivation of the robotic dynamic equations from Hamilton's principle gives rise to natural Lyapunov functions for control design based on total energy considerations. Through a slight modification of the energy Lyapunov function and the use of a convenient lemma to handle third–order terms in the Lyapunov function derivatives, closed–loop exponential stability for both the set point and tracking control problem is demonstrated. In one new design, the nonlinear terms are decoupled from real-time measurements which completely removes the requirement for on–line computation of non–linear terms in the controller implementation. In general, the new class of control laws offers alternatives to the more conventional computed torque method, providing trade–offs between computation and convergence properties. Furthermore, these control laws have the unique feature that they can be adapted in a very simple fashion to achieve asymptotically stable adaptive control.
Chemical and structural defenses of Caribbean gorgonians (Pseudopterogorgia spp.): Intercolony localization of defense (1989)

We have adopted an integrated approach to assessing the function of gorgonian defenses by analyzing within‐colony patterns in the distribution of both structural elements and chemical compounds in two morphologically similar species of Pseudopterogorgia. In both species, crude extract concentrations are higher in polyp‐bearing regions of colonies than in more proximal, nonpolyp‐bearing regions of colonies. The concentration of the ichthyodeterrent terpene from Pseudopterogorgia acerosa (pseudopterolide) is also higher in polyps than in axial tissue. In Pseudopterogorgia rigida, an ichthyodeterrent terpene (curcuhydroquinone) occurs almost exclusively in the polyps and is undetectable in most samples from the axial coenenchyme. The distribution of the calcium carbonate structural elements (sclerites) within colonies is negatively correlated with the concentration of extract. Sclerites comprise the largest percent composition in the axial tissue and a very small proportion of branch tissue. Geographic variation in the negative within‐colony correlation between chemical and structural components indicates the range of variation possible in these defensive traits.
World-stabilized annotations and virtual scene navigation for remote collaboration (2014)

We present a system that supports an augmented shared visual space for live mobile remote collaboration on physical tasks. The remote user can explore the scene independently of the local user's current camera position and can communicate via spatial annotations that are immediately visible to the local user in augmented reality. Our system operates on off-the-shelf hardware and uses real-time visual tracking and modeling, thus not requiring any preparation or instrumentation of the environment. It creates a synergy between video conferencing and remote scene exploration under a unique coherent interface. To evaluate the collaboration with our system, we conducted an extensive outdoor user study with 60 participants comparing our system with two baseline interfaces. Our results indicate an overwhelming user preference (80%) for our system, a high level of usability, as well as performance benefits compared with one of the two baselines.
TABLE OF OUTPUT PROBABILITY DISTRIBUTIONS FOR A QUANTIZING ENVELOPE DETECTOR WITH A SINUSOIDAL SIGNAL IN GAUSSIAN NOISE AT THE INPUT. (1967)

be pulsed) of power S, and a rf interference voltage of power N. The d-c component and the rms value of the a-c component of the output voltage are charted as functions of the rf signal-to-noise ratio S/N for four types of rf interference and for the cases where the saturation (or quantized level) of the output is 2, 3, 4, 5 and 10 times the dc component of the output due to the interference alone. (auth)
The Structure and Constitution of a Mucus. I. The Polyelectrolyte Nature of Mucus Solutions Derived from Busycon canaliculatum (1958)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe Structure and Constitution of a Mucus. I. The Polyelectrolyte Nature of Mucus Solutions Derived from Busycon canaliculatumHarold Kwart and Victor E. ShashouaCite this: J. Am. Chem. Soc. 1958, 80, 9, 2230–2236Publication Date (Print):May 1, 1958Publication History Published online1 May 2002Published inissue 1 May 1958https://pubs.acs.org/doi/10.1021/ja01542a047https://doi.org/10.1021/ja01542a047research-articleACS PublicationsRequest reuse permissionsArticle Views58Altmetric-Citations5LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Impact of dissociation on the viscosity of gases (1995)

Rigorous numerical analysis published in an earlier work [S. H. Kang and J. A. Kunc, Phys. Rev. A 44, 3596 (1991)] has shown that the viscosity–temperature dependence of dissociating iodine vapor can have a negative slope. In this work, a general and easy-to-use procedure is presented which allows the estimation of the range of physical conditions under which such a negative slope can occur in other dissociating diatomic gases.
Influence of carbon nanofiber structure on properties of linear low density polyethylene composites (2009)

Abstract Three types of carbon nanofibers (MJ, Pyrograf®III PR‐19 and PR‐24) were incorporated into linear low density polyethylene (LLDPE) using intensive mixing. The electrical volume resistivity of composites decreased with the addition of CNFs from over 10 12 Ω cm for pure LLDPE to less than 10 4 Ω cm for carbon nanofibers (CNF) contents of 15 wt% or more. Tensile modulus increased from 110 MPa for pure LLDPE to 200 MPa and 300 MPa for 15 wt% MJ and 15 wt% PR composites, respectively. However, the tensile strength remained fairly unchanged at about 20 MPa. Strain‐to‐failure decreased from 690% for pure LLDPE to 460% and 120% for 15 wt% MJ and 15 wt% PR composites, respectively. It was inferred that the interfacial interactions of LLDPE matrix with MJ fibers is better than that with PR fibers, resulting from the rougher surface of MJ fibers. POLYM. ENG. SCI., 2010. © 2009 Society of Plastics Engineers
Pulmonary Metaphor Design and Anesthesia Simulation Testing (2002)

Medical decision making is a crucial process to successfully treat a critical medical emergency. During an unexpected medical event, astronauts, like anesthesiologists, must react quickly in a complex environment. Tools, such as the pulmonary metaphor display, were created to aid the medical caregiver's decision making process. The pulmonary metaphor display is designed to help the caregiver collect and integrate pulmonary data to provide a more accurate, quicker diagnosis and treatment. The following outline anesthesiology simulation study will provide the data to prove that the pulmonary metaphor display is beneficial to medical decision making.
Scattering of electromagnetic waves by the turbulent pulsations in an inhomogeneous magnetoactive plasma (1968)

The authors consider the theory of high-frequency electromagnetic wave scattering by the turbulent pulsations in a plasma contained by an external magnetic field. They analyse in detail the effects accompanying the scattering of waves in both inhomogeneous and homogeneous magnetoactive plasmas. The effects of quasi-elastic and diffusion scattering are also analysed. The possibilities of using calculated scattering effects for diagnosing the turbulent state of a plasma are discussed.
Thrombin-mediated Proteolysis of Factor V Resulting in Gradual B-domain Release and Exposure of the Factor Xa-binding Site (2002)

To investigate the relationship between the individual thrombin cleavages in factor V (FV) and the generation of activated factor X (FXa) cofactor activity, recombinant FV mutants having the cleavage sites eliminated separately or in combination were used. After thrombin incubation, the ability of the FV variants to bind FXa and support prothrombin activation was tested. The interaction between FVa and FXa on the surface of phospholipid was investigated with a direct binding assay as well as in a functional prothrombin activation assay. FV mutated at all cleavage sites functioned poorly as FXa cofactor in prothrombin activation, the apparent K(d) for FXa being approximately 10 nm. Fully activated wild type FVa, yielded an apparent K(d) of around 0.2 nm. The Arg(709) and Arg(1018) cleavages occurred at low thrombin concentrations and decreased the K(d) for FXa binding 5- and 3-fold, respectively. The Arg(1545) cleavage, being less sensitive to thrombin, decreased the K(d) for FXa binding approximately 20-fold. The K(m) for prothrombin was the same for all FV variants, demonstrating B-domain dissociation to result in exposure of binding site for FXa but not for prothrombin. In conclusion, we demonstrate FV activation to be associated with the stepwise release of the B-domain, which results in a gradual exposure of the FXa-binding site.
Predictive factors for short-term visual outcome after intravitreal triamcinolone acetonide injection for diabetic macular oedema: an optical coherence tomography study (2006)

OCT factors and baseline VA can be useful in predicting the outcomes of VA 3 months after intravitreal triamcinolone acetonide injection in patients with refractory DME.