gebhart/patrepeval huggingface dataset:
Potential Inhibitor of COVID-19 Main Protease (M<sup>pro</sup>) From Several Medicinal Plant Compounds by Molecular Docking Study (2020)

COVID-19, a new strain of coronavirus (CoV), was identified in Wuhan, China, in 2019. No specific therapies are available and investigations regarding COVID-19 treatment are lacking. Liu et al. (2020) successfully crystallised the COVID-19 main protease (Mpro), which is a potential drug target. The present study aimed to assess bioactive compounds found in medicinal plants as potential COVID-19 Mpro inhibitors, using a molecular docking study. Molecular docking was performed using Autodock 4.2, with the Lamarckian Genetic Algorithm, to analyse the probability of docking. COVID-19 Mpro was docked with several compounds, and docking was analysed by Autodock 4.2, Pymol version 1.7.4.5 Edu, and Biovia Discovery Studio 4.5. Nelfinavir and lopinavir were used as standards for comparison. The binding energies obtained from the docking of 6LU7 with native ligand, nelfinavir, lopinavir, kaempferol, quercetin, luteolin-7-glucoside, demethoxycurcumin, naringenin, apigenin-7-glucoside, oleuropein, curcumin, catechin, epicatechin-gallate, zingerol, gingerol, and allicin were -8.37, -10.72, -9.41, -8.58, -8.47, -8.17, -7.99, -7.89, -7.83, -7.31, -7.05, -7.24, -6.67, -5.40, -5.38, and -4.03 kcal/mol, respectively. Therefore, nelfinavir and lopinavir may represent potential treatment options, and kaempferol, quercetin, luteolin-7-glucoside, demethoxycurcumin, naringenin, apigenin-7-glucoside, oleuropein, curcumin, catechin, and epicatechin-gallate appeared to have the best potential to act as COVID-19 Mpro inhibitors. However, further research is necessary to investigate their potential medicinal use.
<title>Interferential Wavelengths Comparison With Real-Time Signal Processing</title> (1980)

The two wave field widened interferometer of "Institut National de Metrologie" (I.N.M.) is controlled by Micral R2E microprocessor (Intel 8008) for data acquisition and real time signal processing. Two different methods are described, one involving a servo controlled step by step scanning of the path difference, in the second one this scanning is approximately linear with time, and the microprocessor samples interferometric signal at a high rate. In both methods a real time signal processing is achieved. We compare the results of phase measurements by the two methods ; the reproducibility may be in both cases within a few 10<sup>-4</sup> of a fringe.
Emergence in Human Dental Plaque and Host Distribution of Amylase-binding Streptococci (1994)

Salivary amylase is known to bind specifically to several species of oral streptococci. To assess the importance of this interaction in bacterial colonization of the oral cavity, we determined the proportion and identity of amylase-binding bacteria (ABB) in dental plaque of humans and various salivary amylase-secreting and non-secreting mammalian species. The numbers of ABB in undisturbed plaque collected over time from tooth surfaces of six human volunteers or from 14 other mammalian species were determined by means of a replicating assay. The mean proportion of ABB cultured aerobically from human teeth at 2 h was 10.5% (SD 10), at 8 h 7.9% (8), at 24 h 13% (11), and at 48 h 12% (9). The mean proportion of anaerobically cultured ABB found at 2 h was 3% (SD 4), at 8 h 5% (5), at 24 h 12% (9), and at 48 h 16% (12). Amylase-binding bacteria cultured from these samples resembled Streptococcus mitis, Streptococcus gordonii, Streptococcus salivarius, Streptococcus crista, or unidentified streptococci. In addition, only animals exhibiting salivary amylase activity in their saliva harbored ABB (ranging from 2 to 31% of the total flora), with the exception of the pig, where no ABB were found to colonize, despite considerable amylase activity in saliva. Only strains resembling S. mitis and S. salivarius and unspeciated strains were isolated from these mammals. These results suggest that amylase-binding streptococci are the predominant ABB in human plaque, and their numbers generally increase as plaque develops. Since ABB colonized only the oral cavities of hosts demonstrating salivary amylase activity, the ability to bind amylase may play an important role in oral colonization by these bacteria.
American Eugenics Program (2011)

When the word ‘eugenics’ is mentioned, many people associate it with Nazis and 1940s Germany, if they understand the word in the first place. Few people within the general public are aware that the concept of eugenics has been around much longer— and was not isolated to World War II Germany. Eugenics is not just a past issue; it is the center of much political, philosophical, and religious discourse in the United States. This paper briefly covers the history of American eugenics and what museums are doing to provide information on the topic.
Trust calculation in wireless sensor networks (2011)

A wireless sensor network (WSN) is a collection of distributed sensor nodes to work together for monitoring the physical and environmental conditions. Trust in wireless sensor networks is an important issue and it solves the problem of access control, privacy, secure routing scheme and reliable communication. This paper introduces a new approach to calculate the trust in WSN. The proposed algorithm and the evaluation of the trust value of the node in the network depend on the trust attributes, metrics and trust parameters.
Impaired opsonization by serum from patients with chronic liver disease. (1983)

Serum opsonization of two organisms, E. coli and yeasts (S. cerivisiae), was examined in 68 patients with chronic liver disease (CLD). Impaired opsonization for yeasts was found in seven (29%) of 24 patients with chronic active hepatitis, six (27%) of 22 with alcoholic cirrhosis and five (23%) of 22 with primary biliary cirrhosis. Opsonization for E. coli was normal in patients with primary biliary cirrhosis but impaired in seven (29%) patients with chronic active hepatitis and three (14%) of those with alcoholic cirrhosis. The defect of opsonization in chronic active hepatitis was found mainly in patients with histological evidence of active disease. A deficiency, rather than antagonism or inhibition, of normal opsonization factors was responsible, but could not be related to reduced levels of serum complement factors of either the classical or the alternative pathway present in 45% of the patients with chronic active hepatitis, 71% with alcoholic cirrhosis and 18% of those with primary biliary cirrhosis. Serum from two of 11 patients with impaired opsonization antagonised the function of normal polymorphonuclear leucocytes, and polymorphonuclear leucocytes from six of seven patients had slightly reduced phagocytosis/killing of E. coli opsonized in normal serum. Defects of serum opsonization, complement activity and polymorphonuclear leucocyte function may be causes of the increased susceptibility to bacterial infection in patients with CLD.
Solubilization and regeneration of <i>Vitreoscilla</i> hemoglobin isolated from protein inclusion bodies (1992)

Vitreoscilla hemoglobin (VHb), a homodimeric protein containing two heme groups in its native state, was used as a model to investigate inclusion body approtein solubilization, prosthetic group incorporation, and reactivation. High-level expression in recombinant Escherichia coli results in accumulation of a substantial portion of heme-free VHb in inclusion bodies. VHb can be solubilized from these inclusion bodies by relatively low concentrations of urea with the dissolution midpoint at approximately 3.2M urea. Dissolution in the presence of stoichiometric heme shifts the dissolution midpoint to approximately 4.5M urea without influencing the dissolution properties of contaminant proteins, suggesting the effect is specific for VHb. Denaturation of apoVHb and holoVHb obtained from purified native VHb has midpoints of 2.9M and 5.1M urea, respectively. VHb solubilized from inclusion bodies with urea at concentrations from 0 to 3.5M urea can be regenerated by heme addition without dilution of urea to yield active holoVHb. The fraction of solubilized VHb reconstituted upon heme addition is maximum at around 30% when solubilization and reconstitution is conducted in less than 1M urea. At these low urea concentrations, approximately 5% of inclusion body VHb is solubilized. These results show the utility of prosthetic group addition to reconstitute holoVHb in the presence of urea. Also, these findings suggest that some inclusion body protein has partially folded conformation and that a fractional dissolution and refolding process may be advantageous.
Power Characterization of Isolated Bidirectional Dual-Active-Bridge DC–DC Converter With Dual-Phase-Shift Control (2012)

Compared to the traditional single-phase-shift control, dual-phase-shift (DPS) control can greatly improve the performance of the isolated bidirectional dual-active-bridge dc-dc converter (IBDC). This letter points out some wrong knowledge about transmission power of IBDC under DPS control in the earlier studies. On this basis, this letter gives the detailed theoretical and experimental analyses of the transmission power of IBDC under DPS control. And the experimental results showed agreement with theoretical analysis.
Efecto de la suspensión del riego en prefloración y llenado de grano en el contenido de lisina, triptofano y rendimiento en dos maíces de alta calidad proteínica (2012)

Para conocer la influencia de la suspensión del riego en prefloración y llenado de grano, y en el contenido de lisina y triptófano de dos híbridos de maíz de alta calidad proteínica (H-559C y CML176×CML177) y un maíz normal (H-516), se estableció este experimento durante el ciclo otoño/invierno de 2005 en el sitio experimental 'La Norteña' en la región del Soconusco, Chiapas, México. Se probaron los tratamientos de riego, suspensión de riego en prefloración y suspensión de riego en llenado de grano, en los tres materiales de maíz. En total fueron nueve tratamientos con tres repeticiones, que fueron establecidos bajo un arreglo de parcelas divididas y distribuidos en un diseño de bloques completos al azar en el terreno. Se evaluaron variables morfológicas y fisiológicas del rendimiento por tratamiento y muestreo. Los resultados se analizaron estadísticamente y se compararon entre sí con la prueba de Tukey (P¿0,01). Los resultados mostraron que la suspensión del riego en las dos etapas fenológicas produjo alteraciones en las relaciones hídricas de manera diferente en cada genotipo. La suspensión del riego en prefloración indujo disminución del contenido de lisina y triptófano en el H-559C y el contenido de lisina disminuyó en el CLM176×CLM177 cuando la suspensión del riego se aplicó en el llenado de grano. La suspensión en la etapa de prefloración disminuyó el rendimiento en todos los materiales evaluados y afectó más la morfología, fisiología y el rendimiento de los maíces de alta calidad proteínica, en comparación con la etapa de llenado de grano
Sputtered LiCoO2 Cathode Materials for All-Solid-State Thin-Film Lithium Microbatteries (2019)

This review article presents the literature survey on radio frequency (RF)-magnetron sputtered LiCoO<sub>2</sub> thin films used as cathode materials in all-solid-state rechargeable lithium microbatteries. As the process parameters lead to a variety of texture and preferential orientation, the influence of the sputtering conditions on the deposition of LiCoO<sub>2</sub> thin films are considered. The electrochemical performance is examined as a function of composition of the sputter Ar/O<sub>2</sub> gas mixture, gas flow rate, pressure, nature of substrate, substrate temperature, deposition rate, and annealing temperature. The state-of-the-art of lithium microbatteries fabricated by the rf-sputtering method is also reported.
Coupling induced subband structures and collective single electron behavior in a single layer Si quantum dot array (2006)

We report a study on the coupling induced subband structures and the collective single electron behavior in a single layer Si quantum dot (Si-QD) array, which is fabricated by a layer-by-layer technique using hydrogen diluted silane gas in plasma enhanced chemical vapor deposition system. Unique peak structures are observed in both the I-V and the capacitance-voltage (C-V) characteristics. The total number of electrons charged into the Si-QD array is found to be the same as the number of coupled quantum dots under the electrode. This phenomenon originates from a collective charging behavior of electrons into the subband structures in the Si-QD array, which evolved from the discrete energy levels in the individual Si QDs due to the weak interdot coupling. The different coupling and retention properties for the s-state and p-state subbands as well as the mechanisms for the charging and redistribution of electrons among the subbands are analyzed and discussed.
Synthese und Eigenschaften von Vinyl‐fettsäuren (1956)

Abstract Durch Synthese der Säuren CH 2 = CH · (CH 2 ) n · COOH von n = 0 bis n = 10 war es möglich, die Eigenschaften der Vinyl‐fettsäuren vergleichend zu studieren. Die geprüften physikalischen Eigenschaften entsprechen den bei anderen Reihen beobachteten. Unter den chemischen Eigenschaften ist ein anomales Verhalten gegenüber Rhodan und die Polymerisierbarkeit hervorzuheben.
Research in general Practice. New Strategies - New Methods (1993)

Research, Strategies, Methods
Anatomic Consideration in the Anterior Approach to the Sacro-iliac Joint (1994)

Anatomical study of L4 nerve branch, L5 nerve root, and bony stock in the sacroiliac region was performed in cadaveric specimens to provide anatomical references for anterior fixation of the sacroiliac joint. At 1 cm intervals along the sacro-iliac joint, the distance to the lateral border of the L4 nerve branch (to the lumbosacral trunk) and the L5 nerve root was measured. Computed tomography scans and cadaveric sectioning of the sacro-iliac region were performed to evaluate the bony stock available for fixation and the optimal screw direction to prevent neurologic damage. At 4 cm above the pelvic brim, the L4 nerve branch was a mean distance of 23 mm medial to the sacro-iliac joint, whereas the L5 nerve root was 26 mm. At the pelvic brim, those distances decreased to 10 mm for both structures. Four centimeters cephalad to the pelvic brim, the AP dimension of Sl complex was decreased. Screws that were 1 cm medial to the Sl joint and directed posteriorly and parallel to the joint did not endanger neurologic structures. At four centimeters above the pelvic brim, there is less danger of neurologic injury; however, a decrease in sacral bony stock may affect fixation.
Progressive muscular dystrophy; a preliminary report on treatment with amino acids, folic acid and vitamins. (1953)

Ten patients with progressive muscular dystrophy were given daily oral doses of amino acids, folic acid and selected vitamins. At the time of this report they had been treated by this means for periods varying from two months to one year. Only one had other therapy concurrently. Definite and progressive improvement, objective and subjective, occurred in all cases. Among objective changes noted-not all of them in all cases-were return of strength, increase in size and tonus of atrophic muscles, restoration of normal respiratory action and relief of depression. Patients reported a sense of well-being, increase in strength and a feeling of bodily warmth.
The Terminal Protein Gene 2 of Epstein-Barr Virus Is Transcribed from a Bidirectional Latent Promoter Region (1989)

The intact terminal protein genes (TP1 and TP2) of Epstein-Barr virus (EBV) are created upon infection by circularization of the linear viral genome at its terminal repeats. The structure of the 1.7 kb TP2 latent mRNA has been determined by cDNA analysis and Northern blotting, revealing its close relation to TP1 mRNA. The 1.7 kb transcript is expressed from a different promoter and has a different 5' exon from TP1 but is also spliced across the terminal repeats. The last eight exons are common to the TP1 and TP2 RNAs. The TP2 promoter is 3.3 kb downstream of the TP1 promoter and is part of a bidirectional latent EBV promoter region transcribing the TP2 and the latent membrane protein RNAs in opposite directions.
Performance analysis of polymer based antenna-coils for RFID (2003)

Transponder-labels, -tags or -modules of inductively coupled RFID (Radio Frequency Identification)-systems commonly consist of a substrate with an appropriate transponder-chip or transponder-module mounted on top. The antenna coil is structured on this substrate, usually made of PET, PVC or polyimide and usually consists of a wound wire or etched copper or aluminium structures. As a low cost alternative, conductive polymeric thick film pastes can be used for the production of antenna coils for inductively coupled transponders. These pastes are applied by screen printing or dispensing. In mass production the consequence is a reduction of material costs and processing time. Most popular fillers of the conductive polymer pastes are silver flakes which get connected during the curing process. The conductivities of these compounds are lower in comparison with copper or aluminium. Therefore, the transponder coils made of conductive polymer pastes have substantially higher ohmic losses which influence the functionality of RFID transponders. In this paper, the minimum operating magnetic field strength and powering range of the transponder is considered in detail. A selected reference design with the size of a smart card inlay (47 /spl times/ 74 mm/sup 2/) is used.
Dental fear and anxiety levels of patients attending a dental clinic. (2006)

Some patients are afraid of some of the stimuli involved with dental treatment. This could affect the patient-dentist relationship and the dental treatment plan; therefore, before dental treatment, patients' anxiety and fear levels should be assessed.
Pediatric gastroenterology (1991)

This review is divided into three sections. First is a collection of clinically important observations that have been made or reemphasized over the past year. Most of these reports have come from the adult literature, but all of them have direct relevance to clinical pediatrics. They were selected to provide insight into understanding the pathophysiology of some pediatric disorders, better treatment regimens, and areas for future research. The second section deals with the role of inflammatory mediators and growth factors in the function of the stomach and duodenum in health and disease. Particular attention is paid to the pediatric or developmental issues for which these studies may be important. The final set of articles is specifically developmental in focus. These studies deal with the ontogeny of gastroduodenal function, especially with relation to the development of growth-factor receptor-mediated phenomena. As can be seen, the major focus of this review is the question of cell-to-cell communication. The role of the so-called inflammatory mediators and growth factors seems to be arising as one of the fundamental issues regarding regulation of tissue function in organ development, health, and disease.
A convenient synthesis of 5‐(<i>O</i>,<i>O</i>‐dialkylphosphoryl)‐4‐aryl‐3,4‐dihydropyrimidin‐2(1<i>H</i>)‐ones (2003)

Abstract A general and convenient route for the synthesis of dihydropyrimidines bearing the phosphoryl moiety by a one‐pot cyclocondensation involving aldehydes, urea, and O,O‐dialkyl‐2‐oxo‐propanephosphonates, using ytterbium triflate as catalyst, is reported. © 2003 Wiley Periodicals, Inc. Heteroatom Chem 14:13–17, 2003; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.10058
Plaque Radiotherapy for Juxtapapillary Choroidal Melanoma (1996)

Based on these observations, plaque radiotherapy remains a potential option vs enucleation for the management of juxtapapillary choroidal melanoma.
Radioactivity in strange quark matter (1987)

We develop a mass formula for finite lumps of strange quark matter near flavor equilibrium. Our Fermi-gas model includes surface tension and Coulomb energy but not quantum-chromodynamic radiative corrections. Assuming strange matter is stable in bulk, we investigate the radioactive decays of finite strangelets (clumps of strange matter with baryon number A\ensuremath{\lesssim}${10}^{7}$). We derive conditions governing instability for all decay modes. The regions of baryon number, charge, and hypercharge in which various decays are allowed are illustrated graphically, and flow lines and accumulation lines for decaying strangelets are obtained. Finally, we present typical histories of decaying strangelets.
Tuning Hydrophobicity of TiO<sub>2</sub> Layers with Silanization and Self-Assembled Nanopatterning (2013)

The wettability of TiO2 layers is controlled by forming highly ordered arrays of nanocones using nanopatterning, based on self-assembly and dry etching. Nanopatterning of TiO2 layers is achieved via formation of self-assembled monolayers of SiO2 spheres fabricated using the Langmuir-Blodgett technique, followed by dry etching. Three types of TiO2 layers were fabricated using the sol-gel technique, sputtering, and thermal process in order to address the relationship between the wettability and the structure of TiO2 nanostructures. Compared to a thin film TiO2 layer, the nanopatterned TiO2 samples show a smaller static water contact angle (i.e., where the water contact angle decreases as the etching time increases), which is attributed to the Wenzel equation. When TiO2 layers are coated by 1H,1H,2H,2H-perfluorooctyltrichlorosilane, we observed the opposite behavior, exhibiting superhydrophobicity (up to contact angle of 155°) on the nanopatterned TiO2 layers. Self-assembled nanopatterning of the TiO2 layer may provide an advanced method for producing multifunctional transparent layers with self-cleaning properties.
Why use a nitrate in 1990? (1991)

Nitrates are beneficial because they combine coronary and noncoronary effects. They have proven clinical efficacy, relieving symptoms and documented evidence of ischaemia. They can be given to patients by multiple routes and can be easily combined with other anti-ischaemic drugs including aspirin, heparin, calcium antagonists and beta-blockers.
Reconfigurable E-shaped patch antennas (2009)

This paper discusses the potential of E-shaped patches to be used in reconfigurable antennas. It is shown that the application of a PIFA configuration to dual-band E-shaped patches gives the freedom of independently tuning two resonances in a very wide frequency range, without affecting the antenna general structure and external dimensions. An application of these features to reconfigurable quasi-omnidirectional back-to-back E-shaped patch for laptops is demonstrated. To prove the concept a very simple model of RF MEMS switches is used in a dual-band laptop reconfigurable antenna prototype. In spite of frequency bands toggling (between IEEE 802.11b/g /2.44 GHz/ or WiMAX /3.45 GHz/ and IEEE 802.11a /5.25 GHz or 5.775 GHz/) the radiation pattern is always almost omnidirectional.
Design of Intelligent Access Control System Based on Face Image Recognition Technology (2010)

The simulation application of intelligent access control system based on face recognition was designed.The face image recognition system was designed,through the configuration of interlink function,the simulation test process of feature extraction,classification recognition and recognition result output of face image by visual operation were achieved.Simulation test data indicated that the system had practical value on face image recognition accuracy and reduced computation time.Face image recognition system based on MATLAB could provide convenience of recognition test operation for customers.
A Processless Film For Recording Electron Beam Radiation (1989)

Processless Electron Recording Media are film-based recording materials that instantly produce an image when scanned by a beam of electrons in an electron beam recorder (EBR). No chemical or physical processing is required in order to develop or generate the image. PERM<sup>tm</sup> is the GAF Chemicals Corporation trade name for this type of film.