gebhart/patrepeval huggingface dataset:
Meeting scheduling: an experimental investigation (2002)

Laboratory experiments were conducted to compare the performance of four different mechanisms of meeting scheduling: 1) the communication centered system (face-to-face) wherein individuals negotiate among themselves and arrive at a consensus on the timing of the meeting; 2) e-mail as the sole communication medium with no structured support; 3) the calendar-oriented scheduling mechanism with e-mail connectivity; 4) automated scheduler. The experiment is implemented based on the real task of meeting scheduling among project groups that had to meet several times during a semester to work on their project (regardless of this experiment). Three post-experimental surveys are used to measure satisfaction with the agreed meeting time, perceived efficiency in coordination time and process, and scheduling conflict for the scheduling methods. T-tests indicate that, even with higher conflicts among the group members, participants are more satisfied with the meeting time reached during the face-to-face meeting and overwhelmingly concurred on the high efficiency of face-to-face coordination process.
Expression of C-peptide multiple gene copies in Escherichia coli and stabilities of C-peptide in aqueous solution. (2003)

A gene fragment encoding three copies of proinsulin C-peptide was synthesized and expressed in E. coli and the recombinant proinsulin C-peptide was produced through site-specific cleavage of the resulting gene products. The fusion protein was expressed at high level, about 80 mg/L, as a soluble product in the cytoplasm. Ni-NTA affinity chromatography efficiently separated the expressed fusion protein from the supernatant, to obtain about 37.5 mg/L of the fusion protein with 70% purity. Enzymatic digestion by trypsin and carboxypeptidase B of the fusion protein efficiently released native C-peptide, the overall yield of recombinant C-peptide at a purity over 95% was 1.5 mg/L. The good agreement of amino acids composition, together with shown similarities of the recombinant C-peptide to C-peptide standard in the comparative RP-HPLC analysis and IMMULITE C-Peptide quantitative assay, suggested that the recombinant C-peptide obtained in this report was the native human C-peptide. The investigation of the chemical stability of recombinant human C-peptide in aqueous solutions by RP-HPLC was also reported. The degradation of the recombinant C-peptide showed a marked dependence on pH and temperature. The degradation reaction of C-peptide occurred immediately in pH 3 or pH 9 buffered solution. The degradation reaction of C-peptide followed first-order kinetics in pH 3 buffered solution at 37 degrees C or 70 degrees C, only 40.3% of C-peptide was remained after 10 h at 70 degrees C. The maximum stability was achieved at pH 7.4, more than 90% of C-peptide were detected at pH 7.4 and 37 degrees C after 10 h and at pH 7.4 and 70 degrees C after 5 h. 99% and 96% of C-peptide was remained at pH 7.4 and 37 degrees C after 10 h with and without 10 g/L BSA respectively.
Chemoembolization of unresectable hepatocellular carcinoma: Decreased toxicity with slow-release doxorubicin‑eluting beads compared with lipiodol (2012)

Chemoembolization with lipiodol (TACE) improves survival of selected patients with unresectable hepatocellular carcinoma (HCC), but results in substantial toxicity. To improve treatment tolerance, we conducted this phase II study using doxorubicin-loaded beads (DC Beads®) delivered by selective transcatheter arterial chemoembolization (DEB-TACE). We compared the results with those obtained with TACE in our historical controls. Thirty-five patients were recruited with diagnoses of HCC. Patients received DEB-TACE with doxorubicin loaded on DC Beads. Computed tomography of the upper abdomen was performed one month after DEB-TACE. Historical controls were a group of 70 patients with matched characteristics treated with TACE. After a median follow-up of 14.1 months (range, 6-36 months), 22 patients (63%) had an objective response. There was a statistically significant decrease in liver enzymes (p<0.001), lactate dehydrogenase, (p<0.001) in DEB-TACE-treated patients compared to TACE-treated patients. DEB-TACE with doxorubicin-loaded DC Beads, a safe and reliable treatment for HCC, leads to decreased toxicity compared to TACE.
Biotechnology's Impact on Chemical Processes Only in Its Infancy (1991)

RETURN TO ISSUEPREVNewsNEXTBiotechnology's Impact on Chemical Processes Only in Its InfancyThe technology's impact in industrial applications is likely to come from using engineered enzymes to produce new productsANN M. THAYERView Author Information C&EN Northeast News BureauCite this: Chem. Eng. News 1991, 69, 41, 13–14Publication Date (Print):October 14, 1991Publication History Published online10 November 2010Published inissue 14 October 1991https://pubs.acs.org/doi/10.1021/cen-v069n041.p013https://doi.org/10.1021/cen-v069n041.p013newsACS PublicationsCopyright © 1991 AMERICAN CHEMICAL SOCIETYArticle Views7Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options SUBJECTS:Biotechnology Get e-Alerts
A simple method for quantifying specific mRNAs in small numbers of early mouse embryos (1991)

Amplification of sequences by the polymerase chain reaction (PCR) has become a powerful tool in the study of gene expression. The technique is, in fact, so powerful that it may detect 'leaky transcription'. Thus, it is now important to be able to quantify the transcripts that are amplified to determine whether or not they represent legitimate transcription of target genes. In this paper, we describe a one-step amplification reaction coupled to solution hybridization/RNase protection that is capable of quantitating specific transcripts in total RNA from one to ten preimplantation mouse embryos and is generally applicable to any cloned mRNA sequence.
Effect of medium-chain fatty acids on high fat diet-induced body fat in obese C_(57)BL/6J mice (2011)

Objective To establish an obese C57BL/6J mouse model and observe the effect of medium-chain fatty acids on body fat of obese C57BL/6J mice.Methods Forty male C57BL/6J mice were randomly divided into MCT group,MLCT group,soybean oil group and control group,10 mice in each group,and were fed for 15 weeks.Following parameters were observed including body weight,diet consumption,food efficiency ratio,body fat weight and lipid ratio,number and size of white adipose cells,liver weight and apolipoprotein of C57BL/6J mice in different groups.Results After 15 weeks,the body weight of C57BL/6J mice was 2SD(Standard deviation) higher and the body fat was significantly higher in soybean group than in control group(P0.05).At the end of study,the body fat weight,lipid ratio,liver weight,the number and size of white adipose cells were significantly lower in MLCT and MCT groups than in soybean oil group(P0.05)with no significant difference observed between MLCT and MCT groups(P0.05).However,the apolipoprotein level was significantly lower in MCT group than in soybean oil group(P0.05)with no significant difference noted in diet consumption and food efficiency ratio among the three groups(P0.05).Conclusion High-fat diet can induce obesity in C57BL/6J mice.MLCT and MCT can reduce body weight,body liver weight,body fat weight and the sizes of adipocytes,and improve apolipoprotein of C57BL/6J mice but cannot affect their diet intake.
Chromenone derivatives as receptors for N-benzoylamino acids (1994)

The chromenone derivative 5, easy to synthesize from 2-hydroxyacetophenone 1, has been used to prepare the hosts 7–10 and 12. These combine three hydrogen bonds, π-stacking and chargetransfer interactions for the complexation of N-benzoylamino acids in CDCl3.
Interoperability testing of presence service on IMS platform (2009)

In this paper, we perform experiments on interoperability testing of presence service on IMS platform. Open source implementations such as an IMS platform, a presence server, an XCAP server, and IMS clients are deployed to establish testbed for interoperability testing of presence service. Test cases for SIMPLE presence protocol developed by OMA are applied to our testbed and test results are analyzed in detail. In our experiments, we covered the basic functionalities of the presence service and the interaction between a client and an XCAP server for intra-domain case. And then we explained the testbeds for inter-domain cases and discussed briefly the differences with intra-domain case. As a result, we found that a number of functionalities could not be tested because they are not supported by IMS clients. Also we found a number of problems in presence server and IMS clients, which results in a number of fail verdicts for some test cases.
[Cyclicity, reversibility and compensation of magnetobiological reactions in isolated cells and tissues]. (1986)

Cell sensitivity to a constant magnetic field (CMF) of 100 = 200 Oe was studied on a fibroblast culture using time-lapse microfilming. It was expressed in the phasic development of the motility of cells, intracellular structures and inclusions: a short-term latent phase (10-15 min), an excitation phase (1.5-2 h) and a suppression phase (up to the end of exposure). After field removal the return of cells to the initial state with a slight excess (in 1.5-2 h) was noted. The phasic development, reversibility and compensation of magnetobiological reactions were later on confirmed in studies on the inhibition in CMF of 400-600 Oe of the activity of succinate dehydrogenase and peptidase in isolated surviving rat skeletal muscles, liver and kidney as well as on a model of the reaction of a cytopathogenic effect of lymphocytes from patients with rheumatic fever on human embryonic fibroblasts where a noticeable effect of inhibition with the CMF action on the system of lymphocytes-fibroblasts and, on the contrary, of its activation with adding to fibroblasts lymphocytes preexposed in CMF of 400-600 Oe for 1 and 24 h were revealed and interpreted as supercompensation of the inhibited enzymatic activity of immunocompetent cells. The phasic development, reversibility and compensation of magnetobiological reactions should be necessarily taken into account in working out magnetotherapy.
Is angiogenesis inhibition the Holy Grail of cancer therapy? (2000)

Over the last several decades, oncology research and cancer treatment have concentrated primarily on the cancer cells. Unfortunately, despite the intensive quest to find new and more effective compounds for chemotherapy, the survival rate of patients has not significantly changed. In 1971 Judah Folkman proposed that a solid tumor cannot grow without inducing angiogenesis. Intensive search for molecules blocking the formation of a tumor-nourishing capillary network has identified several promising agents in experimental models. Some of these angiogenesis inhibitors are in clinical trials, but a clear statement about the efficacy cannot be made yet. What are the current trends in angiogenesis research? What areas should we intensively investigate? Can we find the Holy Grail of cancer therapy in the years to come in order to stop the ineffable suffering of millions of cancer patients?
On the Anonymization of Sparse High-Dimensional Data (2008)

Existing research on privacy-preserving data publishing focuses on relational data: in this context, the objective is to enforce privacy-preserving paradigms, such as k- anonymity and lscr-diversity, while minimizing the information loss incurred in the anonymizing process (i.e. maximize data utility). However, existing techniques adopt an indexing- or clustering- based approach, and work well for fixed-schema data, with low dimensionality. Nevertheless, certain applications require privacy-preserving publishing of transaction data (or basket data), which involves hundreds or even thousands of dimensions, rendering existing methods unusable. We propose a novel anonymization method for sparse high-dimensional data. We employ a particular representation that captures the correlation in the underlying data, and facilitates the formation of anonymized groups with low information loss. We propose an efficient anonymization algorithm based on this representation. We show experimentally, using real-life datasets, that our method clearly outperforms existing state-of-the-art in terms of both data utility and computational overhead.
LDAP Programming with Java (2000)

Lightweight Directory Access Protocol (LDAP) is now a staple of enterprise and Internet software environments. Anyone involved with Internet development, where Java(TM) technology is prominent, or in enterprise information systems must understand how to use Java technology--especially the Directory SDK for Java--in order to unlock the power of LDAP.Written by the designer of the Directory SDK for Java and by a leading implementor of directory-based solutions,LDAP Programming with Java(TM) is the first accurate, concise, and complete guide on accessing LDAP from Java applications. Assuming familiarity with Java programming, the book provides a comprehensive discussion of LDAP, from basic directory concepts to the most advanced techniques. It collects in one convenient resource the many innovative and experience-based techniques and approaches programmers have discovered for using the Directory SDK to solve LDAP access challenges.If you are new to LDAP, you will find helpful background information about the role of directories in today's software systems; LDAP methods of storing, accessing, searching, and updating data; and how the Directory SDK for Java helps applications gain access to an LDAP server. Once you have become proficient with the essential concepts and techniques, you can move on to detailed material about authentication, LDAP and JavaScript(TM), working with JavaBeans(TM) for reusable LDAP components, expressing data relationships in a directory, and other advanced LDAP subjects.Specific topics covered include: The LDAP naming and information models The command-line tools of the SDK Authentication with a password, SSL, and SASL Configuring access control Writing LDAP applets for a browser Accessing the SDK from JavaScript Storing configuration and preferences in a directory Encapsulating LDAP functionality in a JavaBean Using LDAP in Java servlets LDAP URLs Multiple threads and multiple connections Referrals and replicated systems LDAP controls Synchronous and asynchronous operations Performance tips LDAP Programming with Java(TM) also presents numerous examples, from simple code snippets to complete components and applications.
Switching performance comparison of the SiC JFET and the SiC JFET/Si MOSFET cascode configuration (2013)

Silicon Carbide (SiC) devices are becoming increasingly available in the market due to the fact that its manufacturing process is more mature. Many are their advantages with respect to the silicon (Si) devices as, for example, higher blocking capability, lower conduction voltage drop and faster transitions, which makes them more suitable for high-power and high-frequency converters. The purpose of this paper is to study the switching behavior of the two configurations more-widely studied in the literature using SiC devices: the normally-on SiC JFET and the cascode using a normally-on SiC JFET and a low-voltage Si MOSFET. A comparison regarding the turn-on and turn-off losses of both configurations is detailed and the results are verified with the experimental efficiency results obtained in a boost converter operating in both Continuous Conduction Mode (CCM) and Discontinuous Conduction Mode (DCM). Furthermore, a special attention will be focused on the switching behavior of the cascode configuration and the effect of its low-voltage MOSFET is analyzed and different Si devices are compared. The study carried out will confirm that the overall switching losses of the JFET are lower, making it more suitable to operate in CCM in terms of the global efficiency of the converter. Nevertheless, the lowest turn-off losses of the cascode highlight this device as the most appropriate one for DCM when ZVS is achieved at the turn-on of the main switch. Finally, all theoretical results have been verified by an experimental 600W boost converter.
Knowledge transfer in vision tasks with incomplete data (2020)

In many machine learning applications, some assumptions are so prevalent as to be left unwritten: all necessary data are available throughout the training process, the training and test data are independent and identically distributed (i.i.d.), and the dataset sampling sufficiently represent the test data of the model's usage scenario. Transfer learning methods can help when some of these assumptions are broken in real life, but still often assume all-time availability of data that the old and new knowledge can be learned from. In practice, necessary data or aspects of them can become inaccessible due to incomplete knowledge of test scenarios, privacy or legal concerns, protection of business leverage, evolving goals, etc. In this thesis, we address three transfer learning scenarios in neural networks that regularly occur in practice but differ from both standard i.i.d. assumptions and common transfer learning data availability assumptions.\n\nFirst, when transferring knowledge from previous tasks but the data used for training them is no longer available, we propose a method to extend and fine-tune the neural network to incorporate new classifiers while retaining the performance of existing classifiers. Second, with unsupervised domain adaptation where the target domain annotations are unavailable, we propose a method to more effectively transfer models to the unsupervised target domain, but guiding it using a common auxiliary task whose ground truth can be obtained for free or is already annotated. Finally, we show that, when test data is not i.i.d. with training data, classifiers are prone to confident but wrong predictions. In practical scenarios where the test data distribution is unknown before deploying the model, we explore ideas in several research fields to reduce confident errors. We observe that calibrated ensembles are the most effective, followed by single models calibrated using temperature scaling.
Chemical Composition of European Propolis: Expected and Unexpected Results (2002)

Ten propolis samples from Bulgaria, Italy and Switzerland were analyzed by GC-MS. As expected, most samples displayed the typical chemical pattern of "poplar" propolis: they contained pinocembrin, pinobanksin and its 3-O-acetate, chrysin, galangin, prenyl esters of caffeic and ferulic acids. Two samples differed significantly: one from the Graubünden Alpine region, Switzerland, rich in phenolic glycerides, and one from Sicily which contained only a limited number of phenolics and was rich in diterpenic acids.
An adaptive wavelet method for nonlinear circuit simulation (1999)

The advance of very large scale integrated (VLSI) systems has been continuously challenging today's circuit simulators in both computational speed and stability. A novel numerical method, the fast wavelet collocation method (FWCM), was first proposed to explore a new direction of circuit simulation. The FWCM uses a totally different numerical means from the classical time-marching or frequency-domain methods and has demonstrated several superior computational properties, such as uniform error distribution and better computational stability, as compared to that provided by the conventional simulation methods. The foundation for using wavelets to expand the solution of ordinary differential equations (ODEs) has been laid previously where linear systems were computed. However, it has not been studied in detail how to effectively apply the FWCM to solving nonlinear systems. In this paper, we explore the iterative and adaptive schemes which extend the FWCM to nonlinear systems. The proposed adaptive procedures mainly address the method of linearization of nonlinear terms after the unknown vector function is expanded into wavelet basis functions. We implemented two different adaptive schemes, multilevel adaptive and multiinterval adaptive, and evaluated their advantages and disadvantages. It is shown that the FWCM can handle nonlinear systems very efficiently with an accuracy as high as O(h/sup 4/) for the solution and fast mapping between the values of the function and their wavelet expansion coefficients in, at most, O(N log N) operations, where h is the discrete time-interval length and N is the total number of collocation points. Furthermore, the derivatives of the unknown function can be calculated with an accuracy of O(h/sup 3/) in O(N log N) operations. Numerical results are presented which match well with the SPICE simulation.
Method of 3D mesh reconstruction from point cloud using elementary vector and geometry analysis (2012)

The method of three dimensional mesh reconstruction is used to supplementing the 3D reconstruction or 3D scanning method, which only provide with point cloud in 3D model. However, the 3D models in mesh mode illustrate clearer appearance and can be used to obtain more information. In addition, the 3D reconstruction has been previously developed by employing the digital fringe pattern projection where the output was formed in the point cloud. Therefore, this paper presents the computerized algorithms to construct the 3D mesh from the point cloud. The algorithm can be done by firstly dividing the point cloud into small volume for parallel calculation. Next, the points in each small volume are connected, which becomes the submesh and then integrated them together. The submesh in each small volume is produced by creating the initial triangle and then expanding triangular construction continually from each side (base) which has been previously generated. The expanded triangles must be satisfied some certain constrains. The point cloud which is filtered from the STL file format was tested using proposed method. The mesh reconstruction is shown with reasonable result.
Analysis of power-ground plane with combination of rectangle and triangle segmentation (2009)

A new power-ground analysis method combining rectangle and triangle partition is proposed for the analysis of the ground bounce noise in high-speed digital electronic systems. In this method, most of an irregular plane is firstly covered by rectangles, and then the rest area is partitioned into triangle meshes. Cavity model is used to analyze rectangular segment and lumped model is used to analyze triangle mesh. As power supply planes often contain large connected area, the resultant inner virtual ports and simulation time can be reduced significantly. Multilayered planes with apertures can also be analyzed by using impedance matrix model. The result is accurate over a wide range of frequency.