gebhart/patrepeval huggingface dataset:
New Metallacarborane Chemistry:  Molybdenum and Tungsten Carbonyl Multidecker Sandwiches. Cluster Dimers Linked via Metal−Metal Bonds<sup>1</sup> (1998)

This article reports the synthesis, characterization, and chemistry of the first molybdenum and tungsten complexes bearing small carborane ligands, including novel M-M-linked dicluster species. The reaction of the nido-2,3-Et(2)C(2)B(4)H(4)(2)(-) dianion with (RCN)(3)M(CO)(3) reagents (M = Mo, W; R = Me, Et) gave the (Et(2)C(2)B(4)H(4))M(CO)(3)(2)(-) anions, which were isolated as lithium (12-crown-4) salts 1b (M = Mo) and 2b (M = W). Treatment of 1b and 2b with Ph(4)PX (X = Cl, Br, I) followed by triflic acid afforded the dimeric products [(Et(2)C(2)B(4)H(4))Mo(CO)(2)](2)(&mgr;-X)(2) (X = Cl (3a), Br (3b), I (3c)) and the corresponding tungsten dimers 4a-c, all of which are red or orange air-stable crystalline solids. X-ray crystallography on 3b revealed a geometry without precedent in small metallacarborane dimers, in which two MC(2)B(4) pentagonal pyramidal clusters are linked via an intercluster metal-metal bond. From NMR and other spectroscopic evidence, the remaining dimeric products 3a, 3c, and 4a-c are proposed to have structures similar to 3b. Decapitation of 3b with HCl/EtOAc in THF gave red solid [(Et(2)C(2)B(3)H(5))Mo(CO)(2)](2)(&mgr;-Br)(2) (5), which is proposed to have two open planar C(2)B(3) end rings and, hence, is a potential building block for linear polymers via deprotonation and metal-ion-stacking reactions. Compound 3b was also generated in a different reaction, involving the nido-Et(2)C(2)B(4)H(5)(-) anion and [Mo(CO)(4)Br](2)[&mgr;-Br](2) which also produced the bis(carboranyl)molybdenum complex (Et(2)C(2)B(4)H(4))(2)Mo(CO)(2) (6), a nearly colorless solid for which a bent sandwich structure is postulated. The reaction of the nido-cobaltacarborane anion CpCo(Et(2)C(2)B(3)H(4))(-) with [Mo(CO)(4)Cl](2)[&mgr;-Cl](2) in toluene gave two isolable products, red CpCo(Et(2)C(2)B(3)H(3))Mo(CO)(4) (7) and dark red [CpCo(Et(2)C(2)B(3)H(3))](2)Mo(CO)(2) (8), which have, respectively, triple-decker and bent-tetradecker sandwich structures based on X-ray crystallographic structure determinations. The reaction of CpCo(Et(2)C(2)B(3)H(4))(-) with [Mo(CO)(4)Br](2)[&mgr;-Br](2) in toluene gave 8 and a known fused-cluster complex Cp(2)Co(2)(Et(4)C(4)B(6)H(6)) (9). Treatment of the CpCo(Et(2)C(2)B(3)H(4))(-) anion with [W(CO)(4)Br](2)[&mgr;-Br](2) afforded red crystalline CpCo(Et(2)C(2)B(3)H(3))W(CO)(4) (10), which on reaction with PhLi followed by Me(3)OBF(4) gave 11, a B(5)-benzyl derivative of 10. X-ray diffraction analyses established triple-decker sandwich structures for both compounds. The new products were characterized by multinuclear NMR, IR, UV-vis, and mass spectroscopy, and elemental analysis, supplemented by electrochemical data on 3b, 8, and 11.
A two stage model for perceptual decision making (2010)

Reference EPFL-TALK-154601 URL: http://www.perceptionweb.com/abstract.cgi?id=v100554 Record created on 2010-11-05, modified on 2017-05-12
Disturbances of the alimentary tract motility and hypermotilinemia in the patients with diabetes mellitus. (1983)

Lower esophageal sphincter pressure (LESP), gastric emptying, small bowel transit time and plasma motilin levels were measured in diabetics and normal subjects in order to investigate the disturbances of the alimentary tract motility and the participation of motilin in these motility disorders. Hypermotilinemia was observed in all diabetics with or without autonomic neuropathy. Low response of LESP to tetragastrin found in diabetics with autonomic neuropathy could not be explained by motilin. Gastric emptying was highly correlated with fasting plasma motilin levels and a significantly accelerated gastric emptying observed in diabetics without complications or diabetics with diarrhea was considered to be due to hypermotilinemia. On the contrary, no significant correlation was observed between small bowel transit time and plasma motilin levels, suggesting no participation of endogenous motilin in the regulation of small bowel transit.
Smoothly Blending Vector Fields for Global Robot Navigation (2006)

We introduce a new algorithm for constructing smooth vector fields for global robot navigation. Given a ddimensional cell complex with each cell a convex polygon, our algorithm defines a number of local vector fields: one for each cell, and one for each face connecting two cells together. We smoothly blend these component vector fields together using bump functions; the precomputation of the component vector field and all queries can be done in linear time. The integral curves of the resulting globally-defined vector field are guaranteed to arrive at a neighborhood of the goal state in finite time. Except for a set of measure zero, the vector field is smooth. The resulting vector field can be used directly to control kinematic systems or can be used to develop dynamic control policies. We prove convergence for the integral curves of the vector fields produced by our algorithm and give examples illustrating the practical advantages of our technique.
Performance evaluation of a ZigBee-based medical sensor network (2009)

Low power consumption and small footprint make 802.15.4/ZigBee based devices well suited for personal healthcare applications, representing a promising alternative to patient monitoring under important scenarios such as emergency, post-op, continuous care, and chronic diseases. However, their use in
New Matrices and Bioencapsulation Processes (2006)

A PVA-matrix is presented which is capable of gelating at room temperature resulting in lens-shaped particles (LentiKats®). Immobilisation of biocatalysts in LentiKats® is possible without significant loss of biological activity. The hydrogels are long term mechanically and chemically stable and show hardly any biodegradability. Using the new JetCutter method uniform and monodisperse beads can be generated from high viscous fluids at large throughput. The technique is suited for technical and industrial scale.
Actividad electromiográfica en el press de banca horizontal en movimientos armónicos y oscilatorios progresivos (2005)

"La influencia del stiffness del Complejo Músculo Tendinoso sobre el Ciclo Estiramiento Acortamiento nos ha sugerido comparar la Actividad Electromiográfica del Press Banca horizontal Armónico con la realización del Press de Banca horizontal Oscilatorio, ambos a altas velocidades de ejecución y con diferentes cargas. Diecisiete sujetos varones (edad: 22,9 ± 0,8 años, peso: 75,0 ± 9,4 kg, talla: 179 ± 6,5 cm, 1 RM = 110 ± 10,6 kg), todos ellos experimentados, aceptaron participar en este estudio. Los resultados muestran diferencias en el tiempo de realización de una repetición y desplazamiento de la barra entre Press De Banca Armónico y Press De Banca Oscilatorio en la mayor parte de registros. Asimismo, el Press De Banca Oscilatorio presenta menor actividad electromiográfica aunque no se encuentran diferencias significativas para cada solicitación de carga ni entre ellas. En el total de los registros se aprecian diferencias significativas entre las solicitaciones de la Porción Clavicular y Porción Esternal en el Press De Banca Armónico en el total de una repetición y al comparar las dos fases de cada movimiento (concéntrica y excéntrica). Sin embargo, en el Press De Banca Oscilatorio se encuentran diferencias significativas entre las solicitaciones de la fase excéntrica y concéntrica de la PC y PE, pero no en el total de una repetición. Los valores de desplazamiento, tiempo y EMG demuestran que el press de banca armónico y press de banca oscilatorio son ejercicios que parecen requerir una diferente solicitación de las estructuras del complejo músculo tendinoso con un posible mayor compromiso en el press de banca oscilatorio del tejido no contráctil. ."
A Black Filler for Rubber from Tire Pyrolysis Char (1995)

The purpose of this paper is to review the requirements that need to be met by a black filler. This paper reviews two major aspects of rubber technology. The first is a review of the black fillers used in rubber compounding. The second is a discussion of the scrap tire generation and disposal issue and how a black reinforcing filler can be generated using scrap tires and pyrolysis, grinding and beneficiation to produce a useful product. There is over 3 billion pounds of carbon filler used in North America. Over 90% of this is as a reinforcing and/or extender filler for rubber. The three types of black, furnace, thermal, and channel are reviewed and their benefits presented. A typical production specification for several grades of carbon black are shown and the actual production results for over 40 lots of carbon black are analyzed for consistency. In addition a brief history of carbon black development and the specific plant and processing needs of carbon black are discussed.
The linked data benchmark council (LDBC) (2012)

TEST 02 - Elsevier's Scopus, the largest abstract and citation database of peer-reviewed literature. Search and access research from the science, technology, medicine, social sciences and arts and humanities fields.
Managed Care, Hospice Use, Site of Death, and Medical Expenditures in the Last Year of Life (2002)

Medicare-insured decedents in California were more than 4 times more likely to be enrolled in MCOs, were 50% more likely to use a hospice, and had a 30% lower hospitalization rate than decedents in Massachusetts, yet there are few differences in out-of-hospital deaths or expenditures in the last year of life. However, patients with cancer using hospice did have significant savings.
Comportamiento de la diarrea causada por virus y bacterias en regiones cercanas a la zona ecuatorial. (2005)

INTRODUCCIÓN: La enfermedad diarreica aguda (EDA) es un problema de salud a nivel mundial que afecta a la población infantil de distintas regiones. Casi todos los estudios epidemiológicos se han hecho en países con estaciones y poco se informa su comportamiento en países sin estaciones, donde la EDA es endémica con picos epidémicos. OBJETIVOS: Contribuir a conocer la conducta de EDA en Colombia y determinar si su comportamiento es diferente en niños menores de cinco años en dos regiones distintas entre sí en geografía y clima. MATERIALES Y MÉTODOS: Se hizo un estudio descriptivo en dos localidades colombianas. Una en la costa atlántica y otra en el centro del país. La muestra se obtuvo en menores de cinco años que consultaron por diarrea a centros asistenciales de cada región. Los microorganismos bacterianos se identificaron mediante pruebas bioquímicas y los virus con técnicas inmunoenzimáticas. En el análisis estadístico se siguieron un ensayo bivariado y pruebas Z de normalidad para verificar si el clima modifica el comportamiento de EDA y si se presenta de manera distinta en las dos regiones. RESULTADOS: En ambas zonas (Cartagena, Bolívar y Facatativa, Cundinamarca) predominó la diarrea viral, frente a la EDA bacteriana. También en ambas el rotavirus fue prevalente. Fue mucho más baja la presencia de astrovirus y adenovirus. No hubo datos con significación estadística para demostrar que las condiciones ambientales y las propias de los niños, alteran el comportamiento de la EDA, pero sí se observó que la EDA por rotavirus se comporta de manera diferente al analizar en forma comparativa las dos regiones del estudio.
Simulation of IRRAS Spectra for Molecules on Oxide Surfaces: CO on TiO<sub>2</sub>(110) (2015)

We explore a method that can simulate infrared reflection–absorption spectroscopy (IRRAS) spectra for molecules adsorbed on semiconductor surfaces. The method makes it possible to directly correlate experimental spectra with possible adsorbate structures. Our example in this paper is CO adsorbed on rutile TiO2(110). We present simulated IRRAS spectra for coverages in the range from 0.125 to 1.5 monolayer (ML). An explanation is provided for the apparent inconsistency in the literature concerning the tilting geometry of 1 ML CO on this surface. We find that a tilted structure (which is also the lowest-energy configuration) generates IRRAS spectra in excellent agreement with the experimental spectra. Furthermore, we predict the adsorption structure for 1.5 ML CO coverage over TiO2(110), which consists of very weakly bound CO molecules on top of the monolayer. In all cases, our simulation method, which is based on density functional theory (DFT) vibrational calculations, produces s- and p-polarized IRRAS spectra in excellent agreement with the experimental spectra.
Adeno-Associated Virus Type 2 Increases Proteosome-Dependent Degradation of p21<sup>WAF1</sup>in a Human Papillomavirus Type 31b-Positive Cervical Carcinoma Line (2006)

Adeno-associated virus type 2 (AAV2) seropositivity is negatively correlated with the development of human papillomavirus (HPV)-associated cervical cancer. We have begun analysis of the molecular mechanisms underlying AAV2-mediated onco-suppression through cell cycle regulation in HPV-infected keratinocytes isolated from a low-grade cervical lesion. AAV2 superinfection of HPV type 31b (HPV31b)-positive cells at early times postinfection resulted in degradation of the cyclin-dependent kinase (CDK) inhibitor p21(WAF1) protein in a proteosome-dependent manner. Downstream consequences of lowering p21(WAF1) levels included a proportional loss of cyclin E/CDK2 complexes bound to p21(WAF1). The loss of stable p21(WAF1)/cyclin E/CDK2 complexes coincided with an increase in CDK2-associated kinase activity and cyclin E levels. Both events have the potential to enhance the G(1)/S transition point mediated by active cyclin E/CDK2 complexes. Concurrently, cyclin A and E2F levels were decreased, conditions reminiscent of delayed entrance into the S phase of the cell cycle. On the other hand, infection of primary human foreskin keratinocytes with AAV2 resulted in upregulation of p21(WAF1) protein levels, reminiscent of a block in G(1) phase progression. We propose that by down regulating p21(WAF1), AAV2 initiates cell cycle activities leading to enhanced G(1)/S phase-like conditions which may be favorable for AAV2-specific functions and may lead to downstream interference with HPV-associated cervical cancer progression.
Bedside Monitoring for Transient Myocardial Ischemia (2011)

Scenario: This ECG (lead V1) was obtained from the bedside monitor on a 63-year-old woman in no apparent distress in the postprocedural unit. The nurse noted new ST elevation. The patient complained of chest pain and fatigue 1 day earlier but her troponin I levels did not indicate infarction. Her history includes obesity, hypertension, smoking, and prior myocardial infarction (MI) with stent placement 1 year ago. Based on her history and symptoms, an angiogram was performed that revealed no significant occlusions, including at the stent location, and all other cardiac structures were normal. The patient was resting comfortably and had no symptoms.Sinus bradycardia at 55/min, first degree atrioventricular block (AVB), possible prior septal infarct and ST elevation consider ischemia. Note the x2 (arrow on figure above) next to the label Trace 2 (V1). This indicates the gain of the ECG has been increased and may explain the increased amplitude of the QS wave and ST segments.The PR interval, while lengthened, is consistent in all of the conducted beats indicating sinus rhythm with first AVB. Any Q wave in lead V1 is suggestive of prior septal MI, which is consistent with this patient’s history. All ECG machines are calibrated for paper speed and sensitivity to electrical current using the gain adjustment. If only the heart rate is being monitored, proper calibration is not critical. However, proper calibration is critical for accurate rhythm and, in particular, ST segment monitoring.Electrocardiographic criteria apply only when standard paper speed is set at 25 mm/s, as seen in the lower left-hand corner. Standard calibration for ST-segment analysis is 1 mV = 10 mm, which means for every mV sensed, 10 mm (2 big boxes) are produced.A criterion for ischemia in V1 is 2 mm or more, which applies only when standard calibration is used. Criteria for ST-segment elevation myocardial infarction (STEMI) using lead V1 are ST-segment elevations greater than 2 mm in both V1 and lead V2. In this example, ST-segment calibration is set at x2, resulting in an increase in the ST amplitude, making the diagnosis of ischemia inaccurate for this patient.The calibration settings should be reset in the bedside monitor and ST segments reassessed and compared to previous ECGs. A 12-lead ECG is warranted to confirm that STEMI is not present (ST elevation>2 mm in both V1 and V2). Adjustment of calibration settings may be necessary in some patients (ie, waveforms are too large or too small), but it should be done with caution, communicated to other clinicians, and documented in the chart.
Prolonged Cell Cycle Arrest in Irradiated Human Diploid Skin Fibroblasts: The Role of Nutrient Deprivation (2000)

Ionizing radiation has been reported to cause an irreversible cell cycle arrest in normal human diploid fibroblasts. However, colony survival assays show that even at high doses of gamma radiation, human diploid fibroblasts do not irreversibly arrest, and that a dose-dependent fraction is capable of continued cycling. In this study, we resolve the apparent discrepancy between colony survival assays and the observed radiation-induced prolonged arrest. Using flow cytometry analysis, we have confirmed that human diploid fibroblasts do exhibit a prolonged cell cycle arrest in both G(1) and G(2)/M phases of the cell cycle. However, a single replacement of fresh growth medium stimulated a fraction of the arrested population of cells to transiently re-enter the cell cycle. Daily medium changes stimulated these irradiated human diploid fibroblasts to continue cycling until they were contact-inhibited. Thus the fraction of human diploid fibroblasts which survive radiation exposure and are capable of cycling appears to permanently arrest as a result of nutrient insufficiency. Western blot analysis demonstrated a radiation-induced elevation in TP53 (formerly known as p53) protein levels within 2 h postirradiation, followed by a decrease to levels comparable to those in unirradiated controls. The TP53 and CDKN1A (formerly known as p21) protein levels were indistinguishable after 24 h and remained elevated for a 6-day period of observation in both control and irradiated cultures. Our studies indicate that human diploid fibroblasts are capable of re-entering the cell cycle after exposure to ionizing radiation and that this re-entry is dependent on a constant supply of nutrients provided by fresh medium changes. The fraction of cells capable of resuming cell cycling is consistent with the surviving fraction of cells in colony assays.
Scanning SCANIIR (Surface Composition Analysis by Neutral and Ion Impact Radiation) Microscope (1992)

A scanning SCANIIR (surface composition analysis by neutral and ion impact radiation) microscope for lateral and in-depth composition analysis of insulators has been developed, employing a photon counting technique with a ratemeter. The spatial resolution of this system was estimated to be about 30 µm by observing Cu(I) 324.8-nm photon images of a 200-mesh circular-type Cu grid. The depth profile of a SiO 2 /Si interface was depicted using a Si(I) 288.2-nm photon, which yields in-depth resolution of approximately 40 nm.
Compliance of the normal and post-thrombotic calf. (1995)

In addition to degree of outflow obstruction and reflux and poor calf muscle pump function, vein wall compliance changes are important in understanding pathophysiology of venous disease. This study compares the pressure/volume relationship in post-thrombotic and healthy legs.Prospective and comparative study.Vascular laboratory.Investigations were performed on 24 apparently normal legs and 30 post-thrombotic limbs as confirmed by phlebography.Dorsal vein pressure and absolute calf volume decrease were recorded simultaneously during outflow form the leg after release of the cuff during venous occlusion air-plethysmography with and without reactive hyperemia. The slope of the pressure/volume outflow curve was calculated. In addition, the distensibility (= collapsibility) was determined as % volume decrease/mmHg. The popliteal and femoral vein diameters were measured in supine and erect position by ultrasound.With and without induced hyperemia the mean slope coefficients of post-thrombotic legs were significantly higher (0.52 +/- 0.22 and 0.53 +/- 0.18) than in normal (0.15 +/- 0.10 and 0.29 +/- 0.11), i.e., the curve steeper since the calf was stiffer, less compliant. The degree of outflow obstruction and severity of skin changes did not affect the slope measurement substantially. Collapsibility during venous outflow was significantly less in post-thrombotic legs. The post-thrombotic veins were less distended on standing.Post-thrombotic calves are less compliant than normal legs mainly due to less compliance of the vein wall, although theoretically reduced venous volume may contribute.
A New Improved High Performance Thin Layer Chromatography (HPTLC) Method for the Detection of Ionophore Antibiotics in Feeds and Animal Tissues (2003)

Abstract Ionophore antibiotics are widely used in veterinary medicine as anticoccidial drugs for poultry and as growth promoters for farm animals. The ionophores, despite their utility, possess a narrow range of safety; several species (horses in particular) appear highly susceptible to the toxic effects of these compounds, compared with other animal species. The purpose of this study was to apply a quantitative high performance thin layer chromatography (HPTLC) method to identify monensin and lasalocid residues in feeds. We then applied this method to the determination of liver residues. Our method, slightly modified from literature data, appears to be specific, linear (r 2 > 0.99), repeatable and reproducible, sensitive (limit of detection of 0.2 µg/g in liver for monensin, 1 µg/g for lasalocid), convenient, and simple to use.
Ty3 Nucleocapsid Controls Localization of Particle Assembly (2007)

Expression of the budding yeast retrotransposon Ty3 results in production of viruslike particles (VLPs) and retrotransposition. The Ty3 major structural protein, Gag3, similar to retrovirus Gag, is processed into capsid, spacer, and nucleocapsid (NC) during VLP maturation. The 57-amino-acid Ty3 NC protein has 17 basic amino acids and contains one copy of the CX(2)CX(4)HX(4)C zinc-binding motif found in retrovirus NC proteins. Ty3 RNA, protein, and VLPs accumulate in clusters associated with RNA processing bodies (P bodies). This study investigated the role of the NC domain in Ty3-P body clustering and VLP assembly. Fifteen Ty3 NC Ala substitution and deletion mutants were examined using transposition, immunoblot, RNA protection, cDNA synthesis, and multimerization assays. Localization of Ty3 proteins and VLPs was characterized microscopically. Substitutions of each of the conserved residues of the zinc-binding motif resulted in the loss of Ty3 RNA packaging. Substitution of the first two of four conserved residues in this motif caused the loss of Ty3 RNA and protein clustering with P bodies and disrupted particle formation. NC was shown to be a mediator of formation of Ty3 RNA foci and association of Ty3 RNA and protein with P bodies. Mutations that disrupted these NC functions resulted in various degrees of Gag3 nuclear localization and a spectrum of different particle states. Our findings are consistent with the model that Ty3 assembly is associated with P-body components. We hypothesize that the NC domain acts as a molecular switch to control Gag3 conformational states that affect both assembly and localization.