gebhart/patrepeval huggingface dataset:
Cleavage of Alkyl o-Hydroxyphenyl Ethers (1962)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCleavage of Alkyl o-Hydroxyphenyl EthersRobert G. LangeCite this: J. Org. Chem. 1962, 27, 6, 2037–2039Publication Date (Print):June 1, 1962Publication History Published online1 May 2002Published inissue 1 June 1962https://pubs.acs.org/doi/10.1021/jo01053a030https://doi.org/10.1021/jo01053a030research-articleACS PublicationsRequest reuse permissionsArticle Views1759Altmetric-Citations70LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Vaccinia protein kinase 2: a second essential serine/threonine protein kinase encoded by vaccinia virus. (1994)

The major protein kinase activity from vaccinia virus core particles was purified to near homogeneity. The protein kinase is a 50-kDa polypeptide that is shown here to phosphorylate primarily seryl residues in alpha-casein, a casein kinase I-specific peptide substrate, and itself through autophosphorylation. The sequence of four peptides derived from the protein kinase demonstrated that it is encoded by the vaccinia virus F10L gene. Expression of the F10L gene product in bacteria as a fusion with glutathione S-transferase confirmed that the vaccinia F10L gene encodes the protein kinase. We have termed this enzyme vaccinia protein kinase 2 (VPK2) to distinguish it from the protein kinase encoded by the vaccinia B1R gene. Targeted disruption of the VPK2 gene with a positive selectable marker demonstrated that all viruses with a disrupted gene also possessed a wild-type gene, suggesting that VPK2 is essential for viability. The discovery of a second essential protein kinase encoded by vaccinia virus, in addition to a protein phosphatase, underscores the importance of protein phosphorylation in poxvirus biogenesis.
The Effect of Employee Job Satisfaction on Program Participation Rates in the Virginia WIC Program (2001)

Many researchers have shown a link between employee job satisfaction and customer satisfaction in the private sector. Customer satisfaction is the end result of whether the particular service and/or a product meet the customer's needs. The purpose of this research project was to assess the level of employee job satisfaction in the Virginia WIC Program and to determine whether a correlation exists between the level of employee job satisfaction and program participation rates. The results of this study showed that high levels of employee job satisfaction were positively correlated to high program participation rates in the Virginia WIC Program.
An Analysis of the Warm-Season Diurnal Cycle over the Continental United States and Northern Mexico in General Circulation Models (2007)

Abstract The diurnal cycle of warm-season rainfall over the continental United States and northern Mexico is analyzed in three global atmospheric general circulation models (AGCMs) from NCEP, GFDL, and the NASA Global Modeling Assimilation Office (GMAO). The results for each model are based on an ensemble of five summer simulations forced with climatological sea surface temperatures. Although the overall patterns of time-mean (summer) rainfall and low-level winds are reasonably well simulated, all three models exhibit substantial regional deficiencies that appear to be related to problems with the diurnal cycle. Especially prominent are the discrepancies in the diurnal cycle of precipitation over the eastern slopes of the Rocky Mountains and adjacent Great Plains, including the failure to adequately capture the observed nocturnal peak. Moreover, the observed late afternoon–early evening eastward propagation of convection from the mountains into the Great Plains is not adequately simulated, contributing to the deficiencies in the diurnal cycle in the Great Plains. In the southeast United States, the models show a general tendency to rain in the early afternoon—several hours earlier than observed. Over the North American monsoon region in the southwest United States and northern Mexico, the phase of the broad-scale diurnal convection appears to be reasonably well simulated, though the coarse resolution of the runs precludes the simulation of key regional phenomena. All three models employ deep convection schemes that assume fundamentally the same buoyancy closure based on simplified versions of the Arakawa–Schubert scheme. Nevertheless, substantial differences between the models in the diurnal cycle of convection highlight the important differences in their implementations and interactions with the boundary layer scheme. An analysis of local diurnal variations of convective available potential energy (CAPE) shows an overall tendency for an afternoon peak—a feature well simulated by the models. The simulated diurnal cycle of rainfall is in phase with the local CAPE variation over the southeast United States and the Rocky Mountains where the local surface boundary forcing is important in regulating the diurnal cycle of convection. On the other hand, the simulated diurnal cycle of rainfall tends to be too strongly tied to CAPE over the Great Plains, where the observed precipitation and CAPE are out of phase, implying that free atmospheric large-scale forcing plays a more important role than surface heat fluxes in initiating or inhibiting convection.
Chemistry of Organic Fluorine Compounds: A Laboratory Manual with Comprehensive Literature Coverage (1976)

Chemistry of organic fluorine compounds : a laboratory manual with comprehensive literature coverage , Chemistry of organic fluorine compounds : a laboratory manual with comprehensive literature coverage , کتابخانه مرکزی دانشگاه علوم پزشکی ایران
Finite Element Analysis of a Contactless Transformer (2013)

Inductively coupling power transfer is an emerging technique, which enables power transfer to loads through air. The contactless transformer is the key component of it, and the design of a transformer is a time-consuming work with a large number of tests. In this paper, a design method of contactless transformer with finite element analysis is presented. First the contactless transformer model is deduced from Maxwell Equations, and the self inductance and mutual inductance computational equations are given as well. Then the magnetic field distributions of contactless transformer with different air gaps are presented by simulation of MAXWELL ANSOFT. Furthermore, the skin and proximity effects are analyzed as well. At last, the results are compared with the experimental results with the same dimension and material. The analyses show that there has a good agreement with each other. So by this method, the design period of a contactless transformer will be shorter than before
Separation of Potent and Poorly Functional Human Lung Accessory Cells Based on Autofluorescence (1989)

Human alveolar macrophages obtained by bronchoalveolar lavage are usually poor accessory cells in in vitro lymphoproliferation assays. However, we recently described a subpopulation of pulmonary mononuclear cells, obtained from minced and enzyme-digested lung, which were potent stimulators of allogeneic T-lymphocyte proliferation. These cells were enriched in loosely adherent mononuclear cell (LAM) fractions, but further study of these accessory cells was hampered by the heterogeneous nature of LAM. It was observed that in the majority of lung tissue sections, most alveolar macrophages were autofluorescent, whereas most interstitial HLA-DR positive cells were not. Therefore autofluorescence was utilized to fractionate LAM in an attempt to remove alveolar macrophages and selectively purify interstitial accessory cells. LAM were separated by flow cytometry using forward and side scatter to exclude lymphocytes, and red autofluorescence to obtain brightly autofluorescent (A pos) and relatively nonautofluorescent (A neg) mononuclear cells. Although both populations contained over 80% HLA-DR positive cells, A pos cells were poor accessory cells, whereas A neg cells were extremely potent stimulators of a mixed leukocyte reaction at all stimulator ratios tested. When A pos cells were added to A neg cells, T-cell proliferation was markedly suppressed in the majority of experiments. Morphologically, A pos cells appeared similar to classical alveolar macrophages with 95% of the cells being large and intensely nonspecific esterase positive. In contrast, the majority of A neg were smaller, B-cell antigen-negative, nonspecific esterase negative, and had a distinctive morphology on Wright-stained smears. We conclude that fractionation of LAM based on autofluorescence is a powerful tool to isolate and characterize lung mononuclear cells that act either as stimulators or as suppressors of immune responses in the lung.
Effect of attenuated viral vaccines on suckling mice infected with LCMV. (1986)

A single intraperitoneal treatment with live Newcastle Disease Virus (NDV) containing attenuated NDV vaccine, and with live infectious bursal disease virus (IBDV) containing attenuated IBDV vaccine, one day before intracerebral infection with lymphocytic choriomeningitis virus (LCMV) increased, whereas a similar treatment with inactivated NDV or IBDV vaccine did not influence the death rate of suckling mice from experimental lymphocytic choriomeningitis. Thus the attenuated live vaccine stimulated, whereas the inactivated ones failed to affect the cell-mediated immune response to LCMV. Control studies set up with the supernatant of plain tissue culture routinely used for the propagation of IBDV have shown that unlike the attenuated NDV vaccine, the immunostimulatory action is associated not so much with the virus itself, as with an as yet unidentified component of the tissue culture supernatant.
Commensal enteric bacteria engender a self-limiting humoral mucosal immune response while permanently colonizing the gut (1995)

We have employed a germfree mouse model to study the development and persistence of a humoral mucosal immune response to a gram-negative murine commensal organism, Morganella morganii. M. morganii bacteria rapidly colonize the gut, resulting in hypertrophy of Peyer's patches (PP), including germinal center reactions (GCR), and the development of specific immunoglobulin A (IgA) responses detected in vitro in PP fragment cultures and by ELISPOT assays of lamina propria cells. The GCR peaks 14 days after infection and begins to wane thereafter. Upon colonization, the organisms successfully translocate to the mesenteric lymph node and spleen, but the number of translocating bacteria begins to drop with the onset of a specific IgA response. A clonal B-cell microculture technique was used to determine the frequency of specific IgA plasmablasts and IgA memory cells. The frequencies of preplasmablasts were seen to be higher in the earlier stages of germinal center development, whereas the frequencies of antigen-specific memory cells appeared to remain at a relatively constant level even after 193 days postmonoassociation. We suggest that a successful secretory IgA response can attenuate chronic stimulation of GCR even though the bacteria persist in the gut. The observed developing hyporesponsiveness to a chronically present commensal organism may be relevant to the use of bacterial vectors for mucosal immunization.
Raising Web Service Updates Efficiency with Dynamic Technologies (2008)

This paper presents a solution which uses OSGi to allow the development of dynamic Web service applications. Taking into account the update efficiency of dynamic applications in general, this solution was developed to increase Web service updates efficiency.
THE TRANSISTORIZED DIPOLE ANTENNAFIER (1963)

The transistorized dipole antennafier is a novel integrated design uniting a resonant half-wave dipole antenna with a VHF transistor amplifier, and providing a simple, stable, compact, high gain, low-noise, and inexpensive element suitable for use alone or in arrays. The design philosophy is to match the resonant dipole directly into the transistor amplifier, eliminating the usual transmission lines and auxiliary tuned circuits. The result is a miximum bandwidth device, with higher gain and better noise performance than is possible in conventional operation using the same components separately. Measurements have been made at 146 mc on a transistorized dipole antennafier, with results of 12. 5 db gain, less than 400 K effective noise temperature, bandwidth approximately equal to that of the dipole antenna itself, and no effect whatever on the radiation pattern of the dipole.
Forskolin: A Successful Therapeutic Phytomolecule (2010)

Forskolin, a labdane diterpene is the main active ingredient in the ayurvedic herb Coleus forskohlii (Labatiae) that has been used in India since ancient times. The root portion of the plant has been traditionally used for medicinal purposes and contains the active constituent, forskolin. Historically, it has been used to treat hypertension, congestive heart failure, eczema, colic, respiratory disorders, painful urination, insomnia, and convulsions. Clinical studies have justified these traditional uses and indicate its therapeutic potential in asthma, angina, psoriasis, and prevention of cancer metastases. The present review summarizes these reports along with the advancements in research on forskolin as a therapeutic molecule.
Temporal Gestalt Perception in Music (1980)

For the historian, time is not the undifferentiated continuum of the theoretical physicist, but a hierarchically ordered network of moments, incidents, episodes, periods, epochs, eras, etc.-i.e., time-spans whose conceptual are determined by the nature of the events or processes occurring within them (or of the historian's interpretation of these events or processes). Similarly for the musician, a piece of music does not consist merely of an inarticulate stream of elementary sounds, but a hierarchically ordered network of sounds, motives, phrases, passages, sections, movements, etc.-i.e., time-spans whose perceptual boundaries are largely determined by the nature of the sounds and sound-configurations occurring within them. What is involved in both cases is a conception of distinct spans of timeat several hierarchical levels-each of which is both internally cohesive and externally segregated from comparable time-spans immediately preceding and following it. Such time-spans (and the events or processes which define them) will here be called temporal gestalt-units (or TGs).
Preparation and Properties of Phosphate Glasses and Glass-Ceramics Containing Large Amounts of Titanium (IV) (1994)

Phosphate glasses containing very large amounts of TiO2 have been prepared in the compositions of (3Na2O⋅67TiO2⋅30P2O5)+5SiO2(mol%) (Glass-1) and (3Na2O⋅72TiO2⋅25P2O5)+5SiO2 (mol%) (Glass-2). The thermal expansion coefficient (α) from 30 to 600°C were 7.7×10-6°C-1 and 6.9×10-6°C-1, respectively. The glass-ceramics prepared by heating Glass-1 at temperatures in 50°C intervals from 800 to 1000°C for 30h had α=0.7-2.2×10-6°C-1 and glass-ceramics prepared by heating Glass-2 at various temperatures from 900 to 1100°C for 30h had a=1.6-8.4×10-7°C-1 in the same temperature range. The bending strengths of the glass-ceramics from Glass-1 were larger than those from Glass-2. The low thermal expansions of these glass-ceramics were attributed to NaTi2(PO4)3-like phase, TiO2 and (TiO)2P2O7 produced by crystallization, and the bending strengths were greatly influenced by the crystalline phases. The NaTi2(PO4)3-like phase seems to be a solid solution of NaTi2(PO4)3 and Si4+, Na1+xTi2P3-xSixO12, as judged from the differences between the lattice parameters of this phase and those of NaTi2(PO4)3.
Partial Update Adaptive Filtering Based on Head-Related Model for In-Vehicle Audio Enhancement (2012)

In-vehicle audio reproduction is a challenging task owing to the music, reverberation, reflection, and noise intentionally and unavoidably propagated in the car. For a multichannel loudspeaker system, the equalizer design is essential for reconstructing a nearly perfect sound field in the reverberation room. In this work, we propose a partial update adaptive algorithm based on the least-mean-square (LMS) approach and head-related transfer functions (HRTFs) to efficiently repress the indirect terms and separate the different timbres resulting from the in-vehicle multichannel playback system. Since HRTFs have played a crucial role in the spatial audio signal processing, introducing this model is shown to facilitate the complexity reduction for a highly nonlinear system. As a result, several examples of numerical design are provided to verify the characteristics of the proposed system.
Reexamination of tympanic membrane temperature as a core temperature (1996)

Controversies surrounding tympanic temperature (Tty) itself and techniques for measuring it have dampened the potential usefulness of Tty in determining core temperature (operationally defined here as the body temperature taken at a deep body site). The present study was designed to address the following questions. 1) Can a tympanic membrane probe be made that is safer and more reliable than its predecessors? 2) Why is the effect of facial cooling and heating on Tty so inconsistent in reports from different laboratories? 3) Is Tty still useful as a measure of core temperature? Data from this study, obtained with a modified thermocouple probe, suggest that the widely reported facial skin cooling effect on Tty is most probably due to thermal contamination from the surrounding ear canal wall and/or suboptimal contact of the probe sensor with the tympanic membrane because 1) Tty that fell during facial cooling was increased to the precooling level by the repositioning of the probe sensor; 2) Tty determined by using a probe with a larger sensor area (the sensor soldered to a steel wire ring)tended to fall in response to facial cooling, whereas Tty determined with a thermally insulated probe ring did not; and 3) Tty obtained under careful positioning of the insulated probe was relatively insensitive to facial cooling or heating. Because Tty was practically identical to esophageal temperature (Tes) in the steady state, i.e., 36.83 +/- 0.20 (SD) degrees C for Tty and 36.87 +/- 0.16 degrees C for Tes at room temperature (n = 11), and because facial cooling had little effect on both Tty and Tes (36.86 +/- 0.17 degrees C for Tty and 36.86 +/- 0.26 degrees C for Tes during facial or scalp skin cooling), we support the postulate that Tty is a good measure of core temperature. The temperature transient in response to foot warming was detected 5 min (n = 2) faster with Tty than with Tes. Thus, with further improvements in the design of the probe. Tty can become a standard for determination of core body temperature.
Comparison of Erosion of Dental Enamel by Four Drinks Using an Intra-Oral Applicance (1998)

There are several causes of erosion - acidic foods and drinks have been implicated and reducing their erosive potential would seem an important area of research. Calcium-citrate-malate (CCM) appeared to have potentially useful properties as an anti-erosion additive. The study aims were to test the ability of an intra-oral enamel slab system to measure erosion and to compare the erosive potential of a citric acid-based orange juice drink either with or without added CCM and a positive and negative control. Eleven adults wore an upper removable appliance for four periods each of 6 days. Each appliance held two enamel slabs which were inserted into the test drinks for 15 min 4 times a day for 6 days. Loss of enamel was quantified by profiling casts of the enamel slabs taken before and after the test period. Loss of enamal was greatest during exposure to a diet phosphoric acid-based cola drink (p < 0.001) but was similar during exposure to the two citric acid-based orange drinks, with or without CCM, and distilled water. The loss of surface enamel measured from a scanning electron micrograph agreed well with the measurement obtained by profilometry. It can be concluded that (a) the intra-oral enamel slab system was able to discriminate between drinks in their erosive potential, and (b) it was not possible to determine if CCM had any potential for reduction in erosion in an acid beverage as the level of erosion observed for both the critic acid-based orange drinks was not statistically significantly different from that observed with distilled water.
Magnetic resonance imaging in assessment of treatment response of gamma knife for brain tumors. (2011)

Diffusion weighted imaging, perfusion weighted imaging and magnetic resonance spectroscopy can provide early assessment of treatment response of gamma knife for brain tumors, and also information of tumor progression or recurrence earlier than conventional MRI. But there are still many questions to be answered which should be based on the development and advancement of MRI and related disciplines.
An efficient implementation of multi matrix clocks in the distributed system (2015)

Multi matrix is extended concept of the matrix clock. The concept of multi matrix clock is used in the distributed computing environment, when multicore processor systems are used in the distributed system. Multi matrix clock gives information of own process event as well as information about other processes which are running concurrently. Multi matrix clock synchronization algorithm is based on exchanging clock information among the nodes and tries to eliminate the effects of non-determinism in the message delay and data processing time. Multi matrix clock may contain many matrices at single events. And these matrices always follow the matrix clock synchronization rule. Multi matrix can be used in the check pointing as well as garbage collection.
Blade System Design Studies Volume I: Composite Technologies for Large Wind Turbine Blades (2002)

As part of the U.S. Department of Energy's Wind Partnerships for Advanced Component Technologies (WindPACT) program, Global Energy Concepts LLC (GEC) is performing a study concerning innovations in materials, processes and structural configurations for application to wind turbine blades in the multi-megawatt range. The project team for this work includes experts in all areas of wind turbine blade design, analysis, manufacture, and testing. Constraints to cost-effective scaling-up of the current commercial blade designs and manufacturing methods are identified, including self-gravity loads, transportation, and environmental considerations. A trade-off study is performed to evaluate the incremental changes in blade cost, weight, and stiffness for a wide range of composite materials, fabric types, and manufacturing processes. Fiberglass/carbon fiber hybrid blades are identified as having a promising combination of cost, weight, stiffness and fatigue resistance. Vacuum-assisted resin transfer molding, resin film infision, and pre-impregnated materials are identified as having benefits in reduced volatile emissions, higher fiber content, and improved laminate quality relative to the baseline wet lay-up process. Alternative structural designs are identified, including jointed configurations to facilitate transportation. Based on the results to date, recommendations are made for further evaluation and testing under this study to verify the predicted material and structural performance.