gebhart/patrepeval huggingface dataset:
Computational tool for modeling and simulation of mechanically ventilated patients (2010)

The mechanical ventilator settings in patients with respiratory diseases like chronic obstructive pulmonary disease (COPD) during episodes of acute respiratory failure (ARF) is not a simple task that in most cases is successful based on the experience of physicians. This paper describes an interactive tool based in mathematical models, developed to make easier the study of the interaction between a mechanical ventilator and a patient. It describes all stages of system development, including simulated ventilatory modes, the pathologies of interest and interaction between the user and the system through a graphical interface developed in Matlab and Simulink. The developed computational tool allows the study of most widely used ventilatory modes and its advantages in the treatment of different kind of patients. The graphical interface displays all variables and parameters in the common way of last generation mechanical ventilators do and it is totally interactive, making possible its use by clinical personal, hiding the complexity of implemented mathematical models to the user. The evaluation in different clinical simulated scenes adjusts properly with recent findings in mechanical ventilation scientific literature.
Adaptive thresholding via Gaussian pyramid (2002)

Automatic thresholding is an essential step in many applications of image analysis and pattern recognition. For highly noisy images whose statistics are not known a priori, the maximum entropy method is used to estimate the threshold for segmentation. Higher order estimation of the threshold which also takes into account the spatial distribution of the gray levels can also be used. However, these methods are difficult to implement and the computational requirements, in terms of speed and memory space, often exceed the hardware capability. Hence, the authors illustrate the application of Gaussian pyramid to reduce the image into a manageable size while preserving most of the content of the image. They also demonstrate the use of high level software, MATLAB, to aid the implementation of these complex algorithms.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Evaluating trace cache on moderate-scale processors (2000)

Trace cache is a new instruction supply mechanism for wide-issue superscalar processors. It caches dynamic instruction traces, each of which consists of multiple basic blocks. As a result, a number of basic blocks are combined into a single large unit, and hence the effective fetch bandwidth is enlarged. The trace cache has been evaluated only on much aggressive superscalar processors. However, an efficient instruction supply mechanism is required also for moderate-scale processors, as media-specific applications increase their importance. The paper evaluates the trace cache fetch mechanism on moderate-scale superscalar processors. A simpler trace cache is proposed, named nonconsecutive basic block buffer (NCB), for the processors. From experimental evaluation, using the NCB improves the instruction supply efficiency by approximately 10% and hence processor performance is also improved by approximately 10% for integer programs.
Machine Learning for PAPR Distortion Reduction in OFDM Systems (2016)

The purpose of the project is to investigate the possibility of using modern machine learning to model nonlinear analog devices like the Power Amplifier (PA), and study the feasibility of using such models in wireless systems design. Orthogonal frequency division multiplexing (OFDM) is one of the most prominent modulation technique used in several standards like 802.11a,802.11n, 802.11ac and more. Telecommunication systems like LTE, LTE/Aand WiMAX are also based on OFDM. Nevertheless, OFDM system shows high peak to average power (PAPR) in time domain because it comprises of many subcarriers added via inverse fast Fourier transform(IFFT). HighPAPR results in an increased symbol error rate, while degrading the efficiency of the PA. Digital predistortion (DPD) still suffers from high symbol error rate (SER) and reduced PA efficiency, when there is an increase in peak back off(PBO). A receiver based nonlinearity distortion reduction approach can be justified by the fact that base stations have high computation power. A iterative-decision-feedback mitigation technique can be implemented as a receiver side compensation assuming memoryless PA nonlinearities. For successful distortion reduction the iterative-decision based technique required the knowledge of the transmitter PA. The author proposes to identify the nonlinear PA model using machine learning techniques like nonlinear regression and deep learning. The results show promising improvement in SER reduction with small PA model learning time.
Efficient site-specific cleavage by RNase MRP requires interaction with two evolutionarily conserved mitochondrial RNA sequences. (1990)

RNase MRP is a site-specific endonuclease that processes primer mitochondrial RNA from the leading-strand origin of mitochondrial DNA replication. Using deletional analysis and saturation mutagenesis, we have determined the substrate requirements for cleavage by mouse mitochondrial RNase MRP. Two regions of sequence homology among vertebrate mitochondrial RNA primers, conserved sequence blocks II and III, were found to be critical for both efficient and accurate cleavage; a third region of sequence homology, conserved sequence block I, was dispensable. Analysis of insertion and deletion mutations within conserved sequence block II demonstrated that the specificity of RNase MRP accommodates the natural sequence heterogeneity of conserved sequence block II in vivo. Heterologous assays with human RNase MRP and mutated mouse mitochondrial RNA substrates indicated that sequences essential for substrate recognition are conserved between mammalian species.
Research and implementation of mobile advertising system based on location service (2017)

To meet the request of real-time and distributed data storage of the advertising system, the paper presents the region matching query technology based on GeoHash algorithm, large data distributed storage of Mongodb database and query technology of Solr search engine on multi dimension query. With it, advertisers achieve fast delivery and promotion of advertising and quick review of ad serving performance. Meanwhile channel users can timely access to advertising information in accordance with their own needs, greatly save the cost of advertising and increase the timeliness and accuracy of advertising.
On M2M communications standards for smart metering (2013)

The paper discusses M2M communications standards for smart metering. One of the our goals is to show the failures of ETSI standartization process for M2M communications. Our paper proposes some extesions to ETSI standards. At the first hand, it is M-Bus protocol and Open Metering System based on M-Bus. The paper shows how to estimate wireless M-bus throughput and how to avoid collisions. After analysis of Open API for M2M, submitted to ETSI, we propose a new approach in the client-side web development - Web Intents. The main goal for our suggestions is to simplify the development phase for new applications by support asynchronous calls and JSON versus XML for data exchange.
Organizational Resource Based Perspective on e-CRM Satisfaction and e-CRM Success (2014)

The purpose of this study is to examine major factors affecting the e-CRM success. The e-CRM influence factors are identified as organizational perspective(process support, management support, and employee support) and resource-based perspective(customer orientation and technology orientation). This study investigates the relationship between e-CRM influence factors and e-CRM satisfaction and the relationship between e-CRM satisfaction and e-CRM success. We collected 171 questionnaires from e-CRM users, and analyzed the research model by AMOS 18.0. The results of this study are as follows. Firstly, process support, management support, employee support, and technology orientation had a positive effect on the e-CRM satisfaction, but the customer orientation had not an effect on e-CRM satisfaction. Secondly, e-CRM satisfaction positively influenced e-CRM success. This study would provide companies with valuable guidelines for the implementation and introduction of e-CRM systems.
Review of operating condition, design parameters and material properties for proton exchange membrane fuel cells (2020)

Studies into the effects of parameters used in the design of proton exchange membrane (PEM) fuel cell have been done. All the modelling parameters considered influenced the performance of the PEM fuel cells. The effect of the operating condition is shown to be significant. Increasing the operating temperature and operating pressure increases the mobility of ions and as a result the ionic conductivity is increased. In addition, the membrane is dried out when the correct humidity is not provided which increases membrane degradation. Adopting good design parameter is necessary for the efficient transportation of both reactants (fuel and oxygen). With regards to the use of flow plates, the serpentine flow plate is highly recommended. Material properties are very important in material selection and new product development. For the membrane electrode area (MEA); the membrane, the ionic conductivity is very important and should be given an important consideration. This investigation thoroughly examined operating condition, design parameters and material properties necessary for PEM fuel cells experiment. The investigation will further accelerate the commercialization of fuel cells and its integration in the automotive industry.
IgA Nephropathy (1994)

To clarify the natural history of IgA nephropathy and to determine important factors in the progressive loss of renal function in affected patients, 121 patients with IgA nephropathy were followed for a median of 92 months. The cumulative probability of not progressing to end-stage renal failure (that is, of renal survival) was 0.87 at 15 years after the onset of 1st symptoms and 0.86 at 10 years after presentation and biopsy. Eight percent of patients progressed to end-stage renal failure, and 12% had a greater than 20% decline in renal function. A complete remission of disease activity was seen in 12% of patients, and the remaining 68% maintained stable renal function. When the final serum creatinine was expressed as a percentage of the initial serum creatinine for each patient and compared with all other variables, a number of factors were found to affect renal outcome. Of the presenting features, increased age, family history of nephritis, longer duration of symptoms, and presence of either nephrotic-range proteinuria or hypertension were all associated, by univariate analysis, with an adverse outcome, while a history of recurrent macroscopic hematuria and infection-associated exacerbations of disease activity were associated with a favorable outcome. Multivariate analysis showed that nephrotic-range proteinuria had an independent adverse effect. Of the initial laboratory findings, by univariate analysis, the number of hyaline casts, the degree of impairment of renal function, the degree of proteinuria, raised beta globulins on serum protein electrophoresis, and serum C4 concentrations were all associated with an adverse outcome, while the severity of initial hematuria and pyuria were associated with a favorable outcome. Renal biopsy findings associated with an adverse outcome by univariate analysis include, on light microscopy, the percentage of glomeruli with global sclerosis or segmental sclerosis or adhesions, the degrees of tubular atrophy or interstitial fibrosis, interstitial inflammation and blood-vessel thickening, and, on immunofluorescence, the intensity of IgA deposition. Multivariate analysis showed independent adverse effects on renal outcome of global glomerulosclerosis, segmental glomerulosclerosis or adhesions, and a combined mesangial and capillary wall deposition of IgM. Features at final assessment or during follow-up associated with an adverse outcome include, by univariate analysis, the number of hyaline casts, the degree of impairment of renal function, the degree of proteinuria, reduced serum IgG and IGM concentrations, reduced final IgA expressed as a percentage of the initial IgA concentration, transient decreases of creatinine clearance during follow-up of > 10% or > 20%, and persistence or development of hypertension.(ABSTRACT TRUNCATED AT 400 WORDS)
Effectiveness of massage therapy for subacute low-back pain: a randomized controlled trial. (2000)

Patients with subacute low-back pain were shown to benefit from massage therapy, as regulated by the College of Massage Therapists of Ontario and delivered by experienced massage therapists.
New principles in ecological regulation – features from the oral cavity (2006)

The ecology of the mouth is unique. The mouth consists of teeth, saliva and crevicular fluid, not present elsewhere in the body. It has several habitats with distinct microfloras. Even a tooth has several ecological locales. Dental plaque (dental biofilm), is a diverse microbial community with channels and voids. It is accumulated most easily in protected areas, i.e. the approximal and crevicular areas of teeth. These areas also have the largest diversity of oral bacteria. Altogether 771 bacterial species have been detected in the oral cavity. More than 50% of the microflora has not yet been cultured in dental caries, periodontitis and the healthy mouth. While saliva is the most important nutrient for supragingival plaque, the serum-like gingival crevicular fluid nourishes the diverse microbiota of the gingival crevice/periodontal pocket. Development of biofilm-mediated diseases probably follows ecological changes in the local milieu, implying that potentially pathogenic members, being sparse under healthy conditions, multiply at the cost of non-pathogenic members due to selective pressures (ecological plaque hypothesis). A number of factors may initiate this local perturbation, such as biofilm, nutrition, pH and redox potential. Also the metabolism of biofilm members can modify physical and chemical properties of the surroundings, promoting disease. The ecological plaque hypothesis implies that plaque-mediated diseases may be prevented/treated by re-establishing the local microbial homeostasis, e.g. through fluoride, sub-MIC levels of antimicrobial agents, change in the alkalinogenic potential of the biofilm, sugar substitutes, treatment of mothers with antimicrobial sealants during the childhood window of Streptococcus mutans infectivity, vaccines, surface modification of oral surfaces, transgenic repair of salivary glands, and interference with quorum sensing and two-component systems in biofilms. Ecological intervention may also be achieved through replacement therapy and probiotics.
A fast method for downlink cell search in TD-SCDMA (2008)

TD-SCDMA cell search is performed in three scenarios: downlink guide slot (DwPTs) position search, downlink synchronization code (SYNC_DL) position search and frame synchronization control. A fast method for every scenarios of downlink cell search in TD-SCDMA is proposed. Based on characteristics of frame and slot structure in TD-SCDMA, power-matching stencil method is used to find the position of downlink guide slot (DwPTs) and definition stencil method is proposed to decide the position of downlink synchronization code (SYNC_DL). Moreover, the problem of channel estimation for TD-SCDMA mobile communication system is investigated and a new fast method for detecting downlink guide channel is derived to control frame synchronization. This new method simplifies calculation complexity, realizes fast and high efficiency network test system and can be applied to TD-SCDMA network planning and optimization. The conclusion can be proved by simulations and field testing which are mentioned.
Coexpression of Bcl-2, c-Myc, and p53 oncoproteins as prognostic discriminants in patients with colorectal carcinoma (1997)

These findings suggest that oncoprotein coexpression possesses significant prognostic and potential therapeutic value; incorporation of molecular markers into future prospective randomized trials is advisable.
Low-Power CMOS RF front-end for non-coherent IR-UWB receiver (2008)

This paper presents a low-power CMOS RF front-end for 3-5 GHz non-coherent impulse-radio ultra-wideband (IR-UWB) receiver. The proposed front-end comprises a variable-gain low noise amplifier (VG-LNA), an active balun and an analog squarer. Current reuse topology has been adopted in both VG-LNA and active balun to reduce the power consumption. The squarer design is based on the quadratic law of MOSFET in saturation and the performance is optimized for 3-5 GHz UWB signal detection using cascode stage and active load. The VG-LNA has a measured maximum voltage gain of 33 dB/12 dB for high/low gain modes with minimum noise figure 3.7 dB/4.2 dB respectively. Measurements show that the proposed RF front-end achieves an input sensitivity of -91 dBm for UWB on-off keying (OOK) input signal at 1 Mbps pulse rate with an energy efficiency of 3.1 nJ/bit.
Comparison of Aptima Trichomonas vaginalis Transcription-Mediated Amplification Assay and BD Affirm VPIII for Detection of T. vaginalis in Symptomatic Women: Performance Parameters and Epidemiological Implications (2011)

Trichomonas vaginalis is an underestimated sexually transmitted infection (STI) associated with numerous clinical sequelae. The true prevalence and clinical impact of trichomoniasis are unknown, as current methods of detection exhibit poor sensitivity compared to molecular amplification methods. Limited data exist comparing the BD Affirm VPIII hybridization assay to the Gen-Probe Aptima T. vaginalis (ATV) transcription-mediated amplification (TMA) assay for detection of T. vaginalis. In this study, specimens from 766 patients were evaluated. Specimens were retrieved consecutively from patients with vaginal complaints and/or with histories suggestive of STI. Study inclusion was dependent upon the request for and collection of both a vaginal swab for Affirm and a specimen for Aptima Combo 2 by the health care provider during the same office visit. Affirm was performed using the specific collection swab and the transport provided for the test. The ATV assay was performed on remnant Aptima Combo 2 specimens. A second ATV TMA assay, utilizing an alternate T. vaginalis primer and probe set, was performed on all specimens positive by the initial TMA and/or the Affirm assay. Infected-patient status was defined as positive T. vaginalis test results by at least 2 assays. Overall, 5.1% of subjects were positive for T. vaginalis. T. vaginalis was most prevalent in women who were 36 to 45 (11.9%), 51 to 60 (7.7%), and 16 to 25 (4.2%) years of age. The ATV assay was statistically more sensitive than the Affirm assay (100% versus 63.4%, P < 0.0001), identifying 36.6% more positive patients.
Digital correction of magnification in pelvic x rays for preoperative planning of hip joint replacements: Theoretical development and clinical results of a new protocol (2005)

The introduction of digital radiological facilities leads to the necessity of digital preoperative planning, which is an essential part of joint replacement surgery. To avoid errors in the preparation and execution of hip surgery, reliable correction of the magnification of the projected hip is a prerequisite. So far, no validated method exists to accomplish this. We present validated geometrical models of the x-ray projection of spheres, relevant for the calibration procedure to correct for the radiographic magnification. With help of these models a new calibration protocol was developed. The validity and precision of this procedure was determined in clinical practice. Magnification factors could be predicted with a maximal margin of error of 1.5%. The new calibration protocol is valid and reliable. The clinical tests revealed that correction of magnification has a 95% margin of error of -3% to +3%. Future research might clarify if a strict calibration protocol, as presented in this study, results in more accurate preoperative planning of hip joint replacements.
Atomic Source of Single Photons in the Telecom Band (2018)

Single atoms and atomlike defects in solids are ideal quantum light sources and memories for quantum networks. However, most atomic transitions are in the ultraviolet-visible portion of the electromagnetic spectrum, where propagation losses in optical fibers are prohibitively large. Here, we observe for the first time the emission of single photons from a single Er^{3+} ion in a solid-state host, whose optical transition at 1.5 μm is in the telecom band, allowing for low-loss propagation in optical fiber. This is enabled by integrating Er^{3+} ions with silicon nanophotonic structures, which results in an enhancement of the photon emission rate by a factor of more than 650. Dozens of distinct ions can be addressed in a single device, and the splitting of the lines in a magnetic field confirms that the optical transitions are coupled to the electronic spin of the Er^{3+} ions. These results are a significant step towards long-distance quantum networks and deterministic quantum logic for photons based on a scalable silicon nanophotonics architecture.
Asymmetric electrowetting—moving droplets by a square wave (2007)

Here droplet oscillation and continuous pumping are demonstrated by asymmetric electrowetting on an open surface with embedded electrodes powered by a square wave electrical signal without control circuits. The polarity effect of electrowetting on an SU-8 and Teflon coated electrode is investigated, and it is found that the theta-V (contact angle-applied voltage) curve is asymmetric along the V = 0 axis by sessile drop and coplanar electrode experiments. A systematic deviation of measured contact angles from the theoretical ones is observed when the electrode beneath the droplet is negatively biased. In the sessile drop experiment, up to a 10 degrees increment of contact angle is measured on a negatively biased electrode. In addition, a coplanar electrode experiment is designed to examine the contact angles at the same applied potential but opposite polarities on two sides of one droplet at the same time. The design of the coplanar electrodes is then expanded to oscillate and transport droplets on square-wave-powered symmetric (square) and asymmetric (polygon) electrodes to demonstrate manipulation capability on an open surface. The frequency of oscillation and the speed of transportation are determined by the frequency of the applied square wave and the pitch of the electrodes. Droplets with different volumes are tested by square waves of varied frequencies and amplitudes. The 1.0 microl droplet is successfully transported on a device with a loop of 24 electrodes continuously at a speed up to 23.6 mm s(-1) when a 9 Hz square wave is applied.
Tiles: a new language mechanism for heterogeneous parallelism (2015)

This paper studies the essence of heterogeneity from the perspective of language mechanism design. The proposed mechanism, called tiles, is a program construct that bridges two relative levels of computation: an outer level of source data in larger, slower or more distributed memory and an inner level of data blocks in smaller, faster or more localized memory.