gebhart/patrepeval huggingface dataset:
Regulatory properties of brain glutamate decarboxylase (GAD): the apoenzyme of GAD is present principally as the smaller of two molecular forms of GAD in brain (1991)

The apoenzyme of glutamate decarboxylase [enzyme without bound cofactor, pyridoxal 5'-phosphate (pyridoxal-P)] serves as a reservoir of inactive glutamate decarboxylase (GAD) that can be activated when additional GABA synthesis is required. We have investigated which of two molecular forms of GAD is present as apoenzyme in synaptosomes and in cortex, caudate nucleus, hippocampus, and cerebellum of rat brain. Endogenous glutamate apodecarboxylase (apoGAD) was labeled by incubating extracts of synaptosomes or punches of each region with 32P-pyridoxal-P, followed by reduction with NaBH4, to link covalently the 32P-pyridoxal-P to GAD. Proteins were separated by SDS-PAGE. Punches from all four brain regions and forebrain synaptosomes contained two forms of GAD with apparent Mrs of 63 and 65 kDa as identified by immunoblotting with four antiGAD sera. Punches and synaptosomes contained a major 32P-pyridoxal-P-labeled band with an apparent Mr of 63 kDa that was stained on immunoblots by the antiGAD serum 1440 and the monoclonal antibody GAD-6, and a minor labeled band at 65 kDa that was stained by the 1440, 6799, and K2 antisera. Synaptosomes contained remarkably few other strongly labeled proteins, but punches contained several other labeled bands. Three additional lines of evidence indicate that the labeled 63-kDa protein is apoGAD: (1) it was purified by immunoaffinity chromatography with the GAD-1 monoclonal antibody; (2) it yielded one major labeled peptide when digested with chymotrypsin, and that peptide appeared identical in peptide-mapping experiments to the labeled active-site peptide isolated from chromatographically prepared rat brain GAD; and (3) its labeling was selectively blocked by 4-deoxypyridoxine 5'-phosphate, a competitive inhibitor of the binding of pyridoxal-P to GAD.(ABSTRACT TRUNCATED AT 250 WORDS)
Le paradoxe de l'enclave ethnique (2018)

À partir d'une enquête ethnographique sur l'intégration des travailleurs chinois à la CGT (2009-2014), cet article analyse les frontières mouvantes de la « communauté » à travers la négociation, la régularisation et la résistance au travail dissimulé. Si l'entre-soi économique favorise l'insertion professionnelle des travailleurs immigrés, il ralentit cependant l'acceptation de la valeur du syndicat et freine la mobilisation, sauf lorsque la régularisation entre en jeu 1 .
Digital Data Acquisition and Processing in an Auger Electron Spectrometer (1980)

The historical development of data systems for Auger electron spectroscopy (AES) is reviewed with the purpose of putting the role of potential modulation differentiation in perspective. Typical current AES systems employ completely analog controls, signal trains, and data output devices. They use potential modulation differentiation with a lock-in amplifier measuring the first harmonic signal component as an approximation to the derivative of the secondary electron energy distribution. This approach to the generation of Auger spectra makes a considerable sacrifice in the signal-to-noise ratio and the quantitative accuracy in an attempt to improve signal “contrast” in the data. This sacrifice is not necessary when the E∙N(E) output, which is available from the cylindrical mirror analyzer (CMA), is used. An AES system is described which uses a mini-computer, a microprocessor, a disk drive, and a graphics terminal to provide digital control functions, a digital signal train, digital data storage and processing, and reconversion to analog only in the final data display devices. This permits the acquisition of the E∙N(E) signal as measured by the CMA with no arbitrarily imposed modulation or system time-constant effects. This approach provides a high dynamic range in the data storage so that all data may be immediately stored in unprocessed form, which precludes the type of information loss that commonly results from incorrect sensitivity settings in analog systems. After the data are stored, a copy of the data may be digitally processed to provide the smoothing or averaging effect of a time constant, to differentiate the data, to integrate over specific peaks, etc. By converting the signal to digital form immediately after it leaves the CMA, the sensitivity to the pickup of stray noise is drastically reduced. The benefits of the digital approach are illustrated through examples from actual applications and through comparison with data from typical analog systems.
Recontouring of the Middle Third of the Face with Onlay Cartilage Plus Free Fascia Graft (1987)

The onlay fascia-cartilage graft technique for malar or maxillary projections can be used for recontouring the middle third of the face. Covering onlay grafts with fascia achieves a smoother contour, concealing the edges in addition to obtaining a more natural anatomical look for the face. The technique has provided a predictable and permanent method of augmenting malar or maxillary projections, and it has produced good aesthetic results.
Care of Medical Instrumentation (1975)

Bio-engineering means much more than academic research—there is now a great deal of complex medical instrumentation in hospitals yet little consideration has been given to its care. This article discusses from practical experience the requirements of a good maintenance service
II Congreso de Escuelas Universitarias de Trabajo Social. (1998)

Sin resumen
Screening of chromosomal region 21q22.3 for mutations in genes associated with neuronal Ca2+ signalling in bipolar affective disorder. (2006)

The therapeutic effect of lithium in bipolar affective disorder may be connected with decreasing intracellular Ca(2+) concentrations. Several linkage studies have identified a potential bipolar affective disorder susceptibility locus within chromosomal region 21q22.3. This locus contains two genes expressed in the brain - ADARB1 and TRPM2 - involved in regulating intracellular Ca(2+) concentrations. The aim of this study was an identification of mutations in the coding sequences of ADARB1 and TRPM2 and their association with bipolar affective disorder. For that purpose we screened 60 patients with bipolar affective disorder and a control group of 66 subjects using single strand conformation polymorphism and sequence analysis. For rapid screening we performed restriction fragment length polymorphism analysis. Screening of bipolar affective disorder patients for mutations in TRPM2 led to identification of three novel and four known transitions. Two transitions resulted in the substitutions: R755C and A890V. Screening of the coding sequence of ADARB1 did not reveal any mutations except one already known transition. A comparison of the transition frequency in patients and controls does not support association of the detected mutations with bipolar affective disorder. According to our results, bipolar affective disorder may not be caused by mutations in ADARB1. However, this study does not exclude TRPM2 as a candidate gene since we have screened only about 30 per cent of the entire coding sequence of this large gene.
Compressive Representation of Three-dimensional Models (2015)

Due to recent developments in data acquisition mechanisms, called 3d scanners, mesh compression has become an important tool for manipulating geometric data in several areas. In this context, a recent approach to the theory of signs called Compressive Sensing states that a signal can be recovered from far fewer samples than those provided by the classical theory. In this paper, we investigate the applicability of this new theory with the purpose of to obtain a compressive representation of geometric meshes. We developed an experiment which combines sampling, compression and reconstruction of various mesh sizes. Besides figuring compression rates, we also measured the relative error between the original mesh and the recovered mesh. We also compare two measurement techniques through their processing times, which are: the use of Gaussian matrices; and the use of Noiselet matrices. Gaussian matrices performed better in terms of processing speed, with equivalent performance in compression capacity. The results indicate that compressive sensing is very useful for mesh compression showing quite comparable results with traditional mesh compression techniques.
Production and Mode of Action of Lactocin 27: Bacteriocin from a Homofermentative <i>Lactobacillus</i> (1975)

Lactobacillus helveticus strain LP27 produced a bacteriocin, lactocin 27, in dialyzable and nondialyzable forms. No evidence was obtained to indicate that lactocin 27 was under the control of extrachromosomal plasmids. Lactocin 27 had a bacteriostatic effect on the indicator, Lactobacillus helveticus strain LS18. It inhibited primarily protein synthesis without affecting deoxyribonucleic acid and ribonucleic acid synthesis or adenosine 5'-triphosphate levels. Treatment of susceptible cells with the lactocin did not cause leakage of ultraviolet-absorbing material, but caused the efflux of potassium ions and the influx of sodium ions. It adsorbed non-specifically to various bacterial species irrespective of their susceptibility to lactocin 27. However, the presence of specific receptors has not been ruled out.
Middle cerebral artery occlusion in the mouse by intraluminal suture coated with poly-l-lysine: neurological and histological validation (1999)

The present study was conducted to validate a modified method of temporary focal cerebral ischemia in the mouse; neurobehavioral function and histopathological infarction were quantitated following various periods of middle cerebral artery occlusion (MCAo). Male C57BL/6 mice were anesthetized with 3% halothane in a mixture of 30%O2/70%N2O delivered by face mask and were subjected to 30- to 180-min of temporary middle cerebral artery occlusion (MCAo) by an intraluminal suture coated with poly-l-lysine. Twenty-eight of 40 mice showed an initial high-grade neurological deficit (30-min MCAo, n=7; 60-min, n=8; 120-min, n=8; 180-min, n=5) when examined during MCAo; these were used for subsequent study. One day after MCAo, behavioral function was re-evaluated, and brains were perfusion-fixed and infarct volumes were measured. The initial neurological deficit improved at 24 h in mice with 30- or 60-min of prior MCAo but tended to persist in mice with 120- or 180-min insults. Following each duration of ischemia, mice exhibited ipsilateral infarcts. Small, inconsistent predominantly subcortical infarcts were present after 30-min MCAo, while longer occlusion periods gave rise to consistent foci of subcortical infarction involving striatum, septum, thalamus, and hippocampus, as well as areas of frontoparietal cortical infarction. The major advantages of the improved intraluminal MCAo model reported here, incorporating sutures coated with poly-l-lysine, include: a 100% incidence of infarction of predictable location and size in mice having an initial neurological deficit. Periods of 60- to 180-min MCA occlusion in this model yield sufficiently reproducible sequelae to permit the effects of various therapeutic agents on neurological outcome and size of infarction to be readily studied.
Model and Experimental Validation of a Load Sensing System With a Critically Lapped Regulator Spool (2005)

A load sensing (LS) system is one in which the pump flow is regulated to keep the pressure drop across an orifice constant and independent of any variation in the load pressure. This ensures that the pressure loss across the orifice is kept to a minimum, thereby increasing efficiency. An LS regulator spool is used to sense the pressure drop across the orifice to control pump delivery. The spool can be underlapped, critically lapped or overlapped. As a trade-off between efficiency and dynamic response, the LS spool is usually critically lapped. This results in a nonlinear model that is sensitive to operating regions.In this paper, a review of published literature on LS systems is briefly summarized. An LS system model is developed and linearized. Procedures to solve these very complex equations are introduced. Because load sensing systems require pressure feedback, stability can often be an issue. Analysis of these systems to determine the steady state and dynamic performance is very difficult to do because of the dependency of the models on the operating point. Linearized models which reflect a methodology to account for changing operating conditions have been developed and have established three distinct regions of operation (labeled “Conditions I, II, and III”). This paper presents the experimental nature of these conditions and provides experimental evidence that the models so derived are valid over certain frequency ranges. The objective of this paper, then, was to establish confidence in the models by examining frequency response performance under these three distinct conditions. The results show that good agreement does exist between the models and their physical counterparts and establishes limitations thereof.This research can assist in the design or optimization of an LS system and help in the development of advanced control strategies for obtaining further efficiency within certain dynamic performance constraints.
Geomechanics Coupled Reservoir Flow Simulation for Diagnostic Fracture Injection Test Design and Interpretation in Shale Reservoirs (2013)

Abstract Diagnostic fracture injection testing (DFIT) is an extremely popular technique to generate direct estimates of some of the key characteristics of shale reservoirs. DFIT analysis is generally done using analytical models traditionally developed for high-permeability reservoirs. The use of DFIT to analyze tight shale reservoirs introduces additional issues regarding applicability of these techniques for tight systems as well as operational issues such as long well shut-in times to obtain reasonable reservoir parameters. In this work we conduct geomechanics coupled reservoir flow simulations in order to forward model and analyze DFITs for tight shale gas reservoirs. This capability greatly enhances our ability to efficiently design the DFITs for tight shale reservoirs. In this work we simulate a typical DFIT using a geomechanics coupled reservoir flow simulator and generate the pre-closure and after-closure pressure response from the flow simulation model. This response is then analyzed using a standard Nolte pre-closure and after-closure analysis technique with an objective to evaluate the reservoir properties. We not only we show the validity of the Nolte analysis technique for tight rocks but we also provide guidelines on the amount of shut-in time required to generate a reasonable estimate of the reservoir properties from DFIT pressure response. We also show that the geomechanics coupled flow simulation of DFIT can provide estimates on fracture dimensions which compare reasonably with those given by more traditional fracture design tools. We demonstrate that the geomechanics coupled reservoir flow simulation provides an additional advantage over traditional fracture design tools in that it can numerically model the system response even after fracture closure.
Service oriented architecture (SOA) a new paradigm to implement dynamic e-business solutions (2006)

Software development has undergone various stages of paradigms - the very last one is called Object-Oriented (O-O) paradigm. Typical of this paradigm has been culminated by several OO programming languages such as C++, Java and VB. With the advent of Internetworking and evolvement of web technologies, business needs, especially isolated service requests/components, put a new demand on new software architecture. Existing models are examined in the light of their constraints and limitations to meet these constant changing business requirements. Service-oriented Architecture (SOA), as the next generation software architecture and through the utilization of the web service, XML and other related technologies provides viable working solution to implement dynamic e-business. This paper discusses SOA model and how it fits into implementing dynamic e-business solutions.
Reciprocal and Nonreciprocal Switches Utilizing Ferrite Junction Circulators (Correspondence) (1963)

The symmetrical ferrite junction circulator has assumed a position of prominence in recent years due to its small physical size and excellent electrical characteristics. The device was described theoretically by Auld, and other investigators have contributed to the design of improved electrical characteristics. Due to their low loss, these circulators have found wide use with parametric and tunnel diode amplifiers. Other applications include duplexers, multiplexer and load isolators.
Real-time Parking Slot Detection for Camera-equipped Vehicles (2019)

This paper proposes a novel camera-based approach for parking slot detection with markings, using surround-view cameras mounted on vehicles. By introducing a pipeline of marking-specific image feature extraction and novel filtering stages, we detect parking slot markings in pinhole cameras as well as in cameras with fisheye lenses without using a computationally intensive bird-view transformation. After projecting a compact set of image features into 3D space, our orientation-specific Hough transform finds explicitly the left and right edges of the parking slot markings in desired orientations, which is the basis for marking detection and tracking. We present a novel technique to detect and track the parking slots in the scene in a coherent manner, that preserves the structure of the overall parking layout and its temporal consistency. Our algorithm is designed to run on low cost hardware used in vehicles and it is shown to run at 30fps on ARM CPUs. We validated our algorithm on videos representing real-world scenarios of parking slots including marking occlusion, degradation and different weather conditions.
BEHAVIORAL ENGINEERING: THE REDUCTION OF SMOKING BEHAVIOR BY A CONDITIONING APPARATUS AND PROCEDURE<sup>1</sup> (1968)

Recent findings from animal conditioning studies have revealed methods of reducing responses to a very low level with a minimum of aversive by-products. These findings were incorporated into the design of a cigarette case that automatically locked itself for a period of time after a cigarette was removed from it. The next cigarette could be taken at the end of the interval, which was signalled by distinctive stimuli. Five heavy smokers were allowed to become accustomed to using the case. Then, the duration for which the case was locked was gradually increased over a period of weeks to about 1 hr. Smoking gradually decreased to the target level of about one-half of a package of cigarettes per day. Control procedures showed that specific features of the apparatus were responsible for the reduction of smoking. The results indicated that this apparatus was sufficiently effective, convenient, and acceptable to smokers to constitute a practical procedure for reducing smoking to the level considered medically safe. The procedure may also have potential for reducing other habit-forming or addictive behaviors.
A Social Network-Based Trust Model for E-Commerce (2008)

The theory of social network and the harvest of trust models are researched. The trust model of e-commerce based on social network is built, and the recommendation path building algorithm is given. After considering the weight of the relationship between Internet members, trust degree of recommendation nodes, trust value attenuation with time and trade risk level about money, the simulation experiment on those factors is performed. The result indicates that the trust network mechanism based on social network is effective for restricting trust attack behavior in Internet and it provides trusty environments for trades of e-commerce between Internet members.
REACTIVE LYSIS: THE COMPLEMENT-MEDIATED LYSIS OF UNSENSITIZED CELLS (1970)

It has been shown that the "activated reactor" that is produced in certain human sera by complement activation is a stable complex of the fifth and sixth component of complement (C56). On interaction with C7, the indicator factor, a complex C567 is formed which for a short time (half-life less than 1 min) has an activated binding site and can attach itself to normal red cell membranes, conferring on them the hemolytic properties of the "heat stable" complement intermediate EC 1 approximately 7, the capacity to be lysed by C8 and C9. These cells have neither antibody nor the complement components up to C3 bound on them. The binding site-activated C567c-can similarly bind to other hydrophobic surfaces, including agarose gel where it forms a "stainable line". If the complex is not bound to a surface, the binding site decays and the resulting complex will no longer give rise to lysis. However it will still inactivate C8 and C9 in solution. The sera that can generate activated reactor apparently do so because they have an excess of C5 and C6, compared to their content of C7. The phenomenon of reactive lysis thus represents complement-mediated lysis of unsensitized cells initiated at the C5 stage by a stable complex (C56) which was generated by complement activation at a distance. The immunochemistry of the phenomenon is described and some of its implications discussed.
Animated panorama from a panning video sequence (2010)

In the recent applications of virtual reality and augmented reality, panoramic-image-based representation of real world environments has received much attention for its advantages over the traditional 3D modeling approaches, such as shorter generation times, faster rendering speeds, higher photorealism, and less storage needed. The drawback is however that it stores only static information of the scene. Panoramic video has been proposed to preserve wide field-of-view dynamic characteristics of the natural environment, which is especially suitable for outdoor sceneries. Its limitation is lack of control of such video. In this paper, a newly developed software program is presented, which takes a single video sequence from a panning camera, and generates a cylindrical panorama embedded with video textures, called animated panorama. The program has the following functions: seamless video textures generation, undesired object removal by video inpainting, and animated panorama player. We claim that the quality of the animated panorama produced by our program is satisfactory to virtual reality applications and the computation time is acceptable for practical use.
Raised cosine interpolation for empirical mode decomposition (2009)

A raised cosine filter based interpolation for the empirical mode decomposition (EMD) technique is presented in this paper as an alternative to the cubic spline interpolation used in the original implementation. By adjusting a parameter in the proposed technique one can control the quality of decomposition of the algorithm. This results in superior performance compared to the original approach which could either mean faster convergence or lower final error under different conditions. An efficient fast Fourier transform (FFT) based implementation of the proposed technique is presented. Further, an adaptive version of this algorithm is introduced that blindly adjusts the parameter value to ensure efficient signal decomposition for any combination of component frequencies of a two-tone signal.
Bauphysik (1998)

Der Begriff „Wärmeschutz im Hochbau“ betrifft Maßnahmen, die notwendig sind, um in beheizten Gebäuden ein für die Menschen behagliches Raumklima zu schaffen. In der Regel wird dabei zusätzlich erwartet, daß die Baukonstruktion vor Schäden durch Feuchteeinwirkung geschützt wird und der Verbrauch an Heizenergie in tragbaren Grenzen bleibt.
Combined removal of Cr, Cd, and Ni from wastes (1984)

Abstract Results of pilot‐plant tests on treating electroplating wastes by alkaline reduction, precipitation, and upflow filtration.