gebhart/patrepeval huggingface dataset:
A Little Honesty Goes a Long Way: The Two-Tier Model for Secure Multiparty Computation. (2014)

Abstract. Secure multiparty computation (MPC) as a service is becoming a tangible reality. In such a service, a population of clients wish to utilize a set of servers to delegate privately and reliably a given computation on their inputs. MPC protocols have a number of desired properties including tolerating active misbehavior by some of the servers and guaranteed output delivery. A fundamental result is that in order to achieve the above, an honest majority among servers is necessary. There are settings, however, where this condition might be overly restrictive, making it important to investigate models where this impossibility result can be circumvented, allowing secure computation to be performed even when the number of malicious participants outweighs the number of honest participants. To this end, we introduce the two-tier model for MPC, where a set of m parties that are guaranteed to be honest (the first tier) remains “hidden ” within a set of n − m servers which are of dubious trustworthiness (the second tier), and where the objective is to perform MPC withstanding a number of active misbehaviors that is larger than m/2. Indeed, assuming αn of the second-tier servers are dishonest (where α ∈ (0, 1)), we present an MPC protocol that can withstand up to (1 − )(1 − α)n/2 additional faults, for any &gt; 0 and m = ω(logn). Somewhat surprisingly, this allows the total number of faulty parties to exceed n/2 across both tiers. We demonstrate that the two-tier model naturally arises in various settings, as in the case, for example, of a resource-constrained service provider wishing to utilize a pre-existing set of servers. 1
Phase I and Pharmacokinetic Study of the (6-Maleimidocaproyl)Hydrazone Derivative of Doxorubicin (2007)

DOXO-EMCH showed a good safety profile and was able to induce tumor regressions in tumor types known to be anthracycline-sensitive tumors, such as breast cancer, small cell lung cancer, and sarcoma. The recommended doxorubicin equivalent dose for phase II studies is 260 mg/m2.
EFFECT OF INTRACAROTID INJECTION OF PITRESSIN, PITOCIN, EPJNEPHRINE AND ACETYLCHOLINE ON ACTH RELEASE IN RATS (1962)

ACTH releasing activities of epinephrine, acetylcholine, Pitressin, synthetic lysine vasopressin and Pitocin injected into the carotid artery of rat were studied.Pitressin and synthetic lysine vasopressin possessed the strongest potencies.The dose threshold of Pitressin to induce an appreciable ACTH release fell between 40 and 80mU per rat.Pitressin incubated with a kidney homogenate lost its ACTH releasing activity.The rise in blood ACTH level following an intracarotid injection of 5ug. epinephrine was not altered when 40mU of Pitressin was administered simultaneously.The authors are indebted to Prof. VINCENT DUVIGNEALD for the synthetic lysine vasopressin employed in this experiment. This study was supported by U. S. P. H. S. grant A-256.
Let the Music Play: An Automated Test Setup for Blind Subjective Evaluation of Music Playback on Mobile Devices (2020)

Several methods for subjective evaluation for audio and speech have been standardized over the last years. However, with the advancement of mobile devices such as smartphones and Bluetooth speakers, people listen to music even outside their home environment, when traveling and in social situations. Conventional comparative methodologies are difficult to use for sound-quality evaluation of such devices, since subjects are likely to include other factors such as brand or design. Hence, we propose an automated test setup to evaluate music and audio playback of portable devices with subjects without revealing the devices or interfering with the tests. Furthermore, an identical placement of the devices in front of the listener is crucial to accommodate the individual acoustic directivity of the device. For this purpose, we use a large motorized turntable on which the devices are mounted so that the playback device is automatically moved to the defined position in advance. An enhanced version of rating software avrateNG enables the automatic playout of musical pieces and appropriate turning of the devices to face the listeners. Devices that can automatically be tested using our setup include Android and iOS smartphones, as well as Bluetooth and wired portable speakers. Preliminary user tests were conducted to verify the practical applicability and stability of the proposed setup.
Usefulness of Selective Arterial Secretin Injection Test for Localization of Gastrinoma in the Zollinger-Ellison Syndrome (1987)

Secretin was injected into a feeding or nonfeeding artery of a gastrinoma and blood samples were taken from the hepatic vein (HV) or a peripheral artery (PA) to measure the changes of serum immunoreactive gastrin concentration (IRG). The IRG in the HV rose within 40 seconds and in the PA rose within 60 seconds after the injection of secretin into a feeding artery, but not after secretin was injected into a nonfeeder. These results indicated that secretin directly stimulates a gastrinoma to release gastrin in vivo. The selective arterial secretin injection test (SASI test) was applied in three patients in whom gastrinomas could not be located by computed tomography, ultrasonography, or arteriography, and functioning gastrinomas were located in all three patients. In one patient, malignant gastrinomas in the head of the pancreas and in the duodenum could be resected radically with the help of this test.
Beneficial pre-stress in laser fabricated, metallic, square cellular sandwich panels (2006)

The fabrication of flat, lightweight, stiff, strong, metallic, square cellular sandwich panels, LASCELLTM (Patent Pending), employing laser cutting and stake welding has been applied to the fabrication of large, watertight door panels and frames in a collaborative program with the Naval Surface Weapons Center Carderock Division – Ship Systems Engineering Station, Philadelphia and Northrop Grumman Corporation, Newport News. Using a restraining fixture, remarkably flat panels and frames have been fabricated with beneficial pre-stress that increases their resistance to failure from the observed failure mode, which is localized, face sheet buckling on the compression side. This paper reports measurement of thermally induced strains at various stages of the welding process with resistance strain gages fastened to panel face sheets. Although further work is needed, measurements so far confirm the development of the beneficial pre-stress.
Electrostatic effects of nanoscale dielectric patches in the modification of Schottky contacts (2009)

We study the electrostatic effects of thin organic films in modifying the interface physics of metal/semiconductor Schottky contacts. We work out analytically the electrostatic parameter space pointing out where interface state effects exceed space-charge effects and vice versa. This is done by introducing another treatment of the electrostatic problem. We also find that the image force effect on the barrier height due to the insertion of a material with lower dielectric constant than the semiconductor in between the Schottky contact is small but positive. This is in contrast to what might be expected from effective-medium theory. We conclude with an examination of ballistic electron emission microscopy results of pentacene modified $\text{Au}/n\text{-Si}(111)$ Schottky diodes as a case study. Using the tools fore mentioned, we infer the local charge neutrality level and density of interface gap states (to an area of $500\ifmmode\times\else\texttimes\fi{}500\text{ }{\text{nm}}^{2}$) from barrier height statistics and pentacene monolayer heights.
Gas-Condensate Flow in Perforated Regions (2005)

Abstract The most crucial region affecting well productivity is the perforated region. Considerable effort has been directed to study this subject, mathematically by many investigators, but they are mainly focused on single-phase flow with limited information on the two-phase flow systems. It has been demonstrated, first by this laboratory and subsequently by other researchers, that the gas and condensate relative permeability (kr) can increase significantly by increasing the flow rate, contrary to the common understanding. This effect, known as positive coupling, complicates the flow of gas and condensate near the wellbore even further when it competes with inertial forces at higher velocities typical of those around perforation tips. The flow of gas and condensate in perforated regions was studied in this work using a finite-element modelling approach. The model allows for changes in fluid properties and accounts for the positive coupling and negative inertial effects using a fractional flow based relative permeability correlation. A sensitivity analysis on the impact of perforation characteristics such as density, phasing, length and radius as well as that of fluid properties, rock characteristics, wellbore radius, fractional flow and rate on well productivity was conducted resulting in some valuable practical guidelines for optimum perforation design. The results were expressed in terms of the productivity ratio, PR, defined as the ratio of the total flow rate of gas and condensate in the perforated completion to that of an unperforated open-hole for the same pressure drop. The results indicated that PR is independent of fluid properties, fractional flow and rates for most practical purposes.
ChemInform Abstract: ACYLATION OF CYCLOPROPYLACETYLENES BY ACYLIUM FLUOROBORATES (1983)

Abstract Die Acylierung der Titelverbindungen (I) bzw. (V) durch in situ aus den Acylfluoriden (II) und BF 3 gebildete Acyltetrafluoroborate wird stark von der Substitution am Cyclopropanring beeinflußt. Das Cyclopropanderivat (I) reagiert unter Ringerweiterung und in weitgehend stereospezifischer Reaktion zu dem vorwiegend das Z‐Isomere (III) enthaltenden Gemisch der Fluorcyclobutane (III) und (IV).
TEE Beam Manufacturing Analysis for Weight Reduction and Producibility (1994)

This report analyzes the manufacturing of tee shapes for stiffening ship structure. Tees produced by the traditional method of deflanging hot-rolled I-beams (I/T shapes) have been compared to fabricated tee-shapes produced from plate for a target group of 1700 tees used in a DDG-51 class vessel. A review of design considerations for several structures has showed that weight savings averaging 18% were possible while still maintaining strength. To produce a DDG, flanges must be stripped from I-beams totaling more than 690 tons [of 2240 pounds] in weight, producing some 170 tons of scrap, a material loss of 25%, easily in excess of $90,000. Given that weight and cost savings are possible by converting UT shapes to fabricated tees, an evaluation of methods to produce tee sections was undertaken. Both fabricating and stripping methods were considered, including newer technologies such as plasma cutting and laser cutting and welding. Mock-up testing was performed using several candidate technologies and the results compared. Plasma-arc cutting reduced distortion on forty-foot test beams by 50% compared to oxyfuel methods. Economic analysis revealed that fabricated tees were less costly to produce than deflanged I-beams, and that handling functions were the greatest cost element of the traditional oxyfuel cutting methodology.
Fiber-waviness Model in Filament Winding Process (2010)

Fiber waviness is one of the initial defects in the filament winding process, and causes reduction of compressive strength of the composite structure. The mechanism of growth of fiber waviness is, however, not completely clear. In the present study, a model for generating fiber waviness is proposed. It is assumed to be due to local fiber micro-buckling arising from the compression load caused by shrinkage of a metal jig. Three faults are considered as causes of micro-buckling: bonding between metal jig and composite, insufficient cure of the resin, and initial deflection of fibers. Analysis and experiments based on this model have been carried out.
Active seat suspension for ultra-compact vehicle (Fundamental consideration on electromyogram when fall from the bump) (2014)

In these days automobile industry, the request for ultra-compact electric vehicles has been increasing in Japan. Unlike conventional automobiles, such ultra-compact electric vehicles may frequently travel on roads of poor condition, such as narrow and unpaved roads. These roads have bumps and many small obstacles, and therefore, the ride comfort of the vehicles is expected to deteriorate. Therefore, it is concerned regarding lack of visibility and the head protection functions. We suggest active seat suspension to improve the ride comfort by the disorder road run as a high value-added product. The active seat suspension carried voice coil motor (VCM) which is a kind of a linear motor as actuator. The objective of this study is to inspect utility and the effectiveness of the active seat suspension. In this paper, we focused on the neck electricmyogram and seat acceleration when fall from the bump.
Acute Release of Tissue Factor Pathway Inhibitor after In Vivo Thrombin Generation in Baboons (1999)

Tissue factor pathway inhibitor (TFPI), the major downregulator of the procoagulant activity of tissue factor (TF), is synthesised by endothelial cells (EC) and acutely released in vitro after thrombin stimulation. Expression of TF on EC and subsequent thrombin generation occurs in vivo during sepsis or malignancy, inducing disseminated intravascular coagulation (DIC). The present study investigates the changes in plasma TFPI in relation to markers of in vivo thrombin generation induced by injection of factor Xa (FXa)/phospholipids in baboons at dosages leading to partial (48%) or complete fibrinogen depletion. The plasma concentrations of thrombin-antithrombin III (TAT) and fibrinopeptide A (FpA), as markers of in vivo generation of thrombin, were strongly enhanced after injection of FXa/phospholipids. TFPI levels, whether measured as antigen or activity, increased significantly in both treatment groups within few minutes, and were dependent on the dose of FXa/phospholipids. Significant positive correlations between plasma levels of TFPI and of TAT or FpA were observed. Altogether, our results indicate that experimentally induced in vivo generation of thrombin causes the acute release of TFPI, high-lighting a possible novel function of thrombin in downregulation of the coagulation process, potentially relevant for the outcome of DIC.
Prevention and detection of intrusions in wireless sensor networks (2013)

We report on the adaptation and evaluation of an existing approach to multicultural education into an eight-session online, modular curriculum for psychiatric mental health nurse practitioner students (n = 6) and psychology interns (n = 10). Training participants were invited to complete verbal feedback, self-report questionnaires, and a high-fidelity patient simulation before and after the training. Self-report questionnaire results revealed no changes in knowledge or attitudes, but qualitative analysis of verbal feedback reflected improvements in attitudes and behaviors relevant to cultural competence. Results from the simulation also demonstrated an increase in measurable cultural competence behavioral indicators.
Interpolation de signaux par conservation de la régularité Hölderienne (2003)

National audience
Fibrillar Colloidal Boehmite; Progressive Conversion to Gamma, Theta, and Alpha Aluminas (1961)

The conversion of boehmite to transition aluminas and to alpha (corundum) was studied with ( a ) fibrillar colloidal boehmite, about 50 a.u. in diameter, ( b ) finely divided boehmite in the form of thin elongated platelets, and ( c ) macroscopic boehmite crystals. In the range 500 o to 700 o C., ( a ) was converted to fibrillar gamma, essentially unchanged in size or shape, ( b ) was dehydrated to gamma, but the platelets appeared to be partly cracked longitudinally about every 70 a.u., and ( c ) was similarly cracked into much smaller crystallites of gamma. At about 1000 o C., ( a ) yielded only rodlike theta alumina, whereas ( b ) and ( c ) appeared to give a mixture of theta and delta aluminas, characterized by round holes or pores developed from the cracks. In the range 1000 o to 1100 o C., all the aluminas were converted to alpha, at a rate which was strongly dependent on temperature. The conversion of ( a ) and ( b ) to alpha could be followed by subsequent examination with the electron microscope. The alpha crystals, once nucleated, apparently grew rapidly to 0.5 or 1.0 μ in size, since there was no evidence of smaller alpha crystals. The smaller alpha crystals appeared to grow while embedded in a glassy matrix which must have been amorphous alumina. This phase acted as a bridge between the diminishing theta particles and the growing alpha crystals and may have consisted of the alumina which was in the process of being transported.
Screening for YAP Inhibitors Identifies Statins as Modulators of Fibrosis (2020)

Idiopathic pulmonary fibrosis is a lung disease with limited therapeutic options that is characterized by pathological fibroblast activation and aberrant lung remodeling with scar formation. YAP (Yes-associated protein) is a transcriptional coactivator that mediates mechanical and biochemical signals controlling fibroblast activation. In this study, we developed a high-throughput small-molecule screen for YAP inhibitors in primary human lung fibroblasts. Multiple HMG-CoA (hydroxymethylglutaryl-coenzyme A) reductase inhibitors (statins) were found to inhibit YAP nuclear localization via induction of YAP phosphorylation, cytoplasmic retention, and degradation. We further show that the mevalonate pathway regulates YAP activation, and that simvastatin treatment reduces fibrosis markers in activated human lung fibroblasts and in the bleomycin mouse model of pulmonary fibrosis. Finally, we show that simvastatin modulates YAP <i>in vivo</i> in mouse lung fibroblasts. Our results highlight the potential of small-molecule screens for YAP inhibitors and provide a mechanism for the antifibrotic activity of statins in idiopathic pulmonary fibrosis.
Genetic Variants of Factor B in a Population of Jordan (1986)

BF phenotyping was performed in a population of Jordan. The observed allele frequencies were as follows: BF*S = 0.5457, BF*F = 0.3744, BF*SO7 = 0.0763, BF*F1 = 0.0075. These values are in agreement with the geographic position and the ethnic composition of Jordan.
What Can We Do? (2014)

Don’t Get Fooled: Why Can’t We Just Build a New, More Secure Internet? The proposal started out as an April Fool’s joke, but many people still took it seriously. Steve Bellovin, a computer network and security researcher, can claim to have literally written the...
Electron Microscopic Studies of Replicating and Catenated Colicin Factor E1 DNA Isolated from Minicells (1972)

Replicating and catenated DNA molecules of colicin factor E1 that were isolated from minicells were observed by electron microscopy. Two new replicating structures that have been found include: molecules that contain two untwisted replicated branches of the same length and a twisted unreplicated branch, and a twisted circular molecule with a long tail. Other molecular forms identified include circular dimers, three types of catenated dimers (open-open, open-twisted, and twisted-twisted), catenated dimers in which one of the linked molecules is replicating, catenated trimers, and a tetamer.
Improving data locality with loop transformations (1996)

In the past decade, processor speed has become significantly faster than memory speed. Small, fast cache memories are designed to overcome this discrepancy, but they are only effective when programs exhibit data locality . In the this article, we present compiler optimizations to improve data locality based on a simple yet accurate cost model. The model computes both temporal and spatial reuse of cache lines to find desirable loop organizations. The cost model drives the application of compound transformations consisting of loop permutation, loop fusion, loop distribution, and loop reversal. To validate our optimization strategy, we implemented our algorithms and ran experiments on a large collection of scientific programs and kernels. Experiments illustrate that for kernels our model and algorithm can select and achieve the best loop structure for a nest. For over 30 complete applications, we executed the original and transformed versions and simulated cache hit rates. We collected statistics about the inherent characteristics of these programs and our ability to improve their data locality. To our knowledge, these studies are the first of such breadth and depth. We found performance improvements were difficult to achieve bacause benchmark programs typically have high hit rates even for small data caches; however, our optimizations significanty improved several programs.
Oligonucleotide Microarrays Identified Potential Regulatory Genes Related to Early Outward Arterial Remodeling Induced by Tissue Plasminogen Activator (2019)

Constrictive vascular remodeling limiting blood flow, as well as compensatory outward remodeling, has been observed in many cardiovascular diseases; however, the underlying mechanisms regulating the remodeling response of the vessels remain unclear. Plasminogen activators (PA) are involved in many of the processes of vascular remodeling. We have shown previously that increased levels of tissue-type PA (tPA) contributes to outward vascular remodeling. To elucidate the mechanisms involved in the induction of outward remodeling we characterized changes in the expression profiles of 8799 genes in injured rat carotid arteries 1 and 4 days after recombinant tPA treatment compared to vehicle. Periadventitial tPA significantly increased lumen size and vessel area, encompassed by the external elastic lamina, at both one and 4 days after treatment. Among 41 differentially expressed known genes 1 day after tPA application, five genes were involved in gene transcription, five genes were related to the regulation of vascular tone [for example, thromboxane A2 receptor (D32080) or non-selective-type endothelin receptor (S65355)], and eight genes were identified as participating in vascular innervation [for example, calpain (D14478) or neural cell adhesion molecule L1 (X59149)]. Four days after injury in tPA-treated arteries, four genes, regulating vascular tone, were differentially expressed. Thus, tPA promotes outward arterial remodeling after injury, at least in part, by regulating expression of genes in the vessel wall related to function of the nervous system and vascular tone.
Drosophila ARSs contain the yeast<i>ARS</i>consensus sequence and a replication enhancer (1986)

A number of restriction fragments that function as autonomously replicating sequences (ARSs) in yeast have been isolated from Drosophila melanogaster DNA. The behaviour in yeast of plasmids containing Drosophila ARS elements was studied and compared to that exhibited by the archetypal yeast ARS-1 plasmid. ARS functions were localised by subcloning and BAL-31 deletion analysis. These studies demonstrated the structural and functional complexity of Drosophila ARSs. Each Drosophila ARS element has at least two domains, one essential for replication (the replication sequence, RS) and a second (the replication enhancer, RE) which is essential for maximum function of the RS. The RS of three Drosophila ARSs was shown to contain a sequence identical to an 11 bp yeast ARS consensus sequence (5' A/T TTTATPuTTT A/T 3'). These observations lend support to the hypothesis that heterologous ARS elements may be of biological significance.