gebhart/patrepeval huggingface dataset:
Lanthanide Oxide Sulphides (1988)

A systematic account is given of the methods of preparation of oxide sulphides having the composition Ln2O2S (where Ln = lanthanide, Sc, or Y) in the form of polycrystalline materials, single crystals, thin films, and ceramics. The crystal-chemical, thermal, thermodynamic properties of the oxide sulphides are considered. The bibliography includes 117 references.
Study on the Pd/C‐Catalyzed (Retro‐)Michael Addition Reaction of Activated Methylene Compounds to Electron‐Poor Styrenes (2010)

Abstract Palladium on carbon (10 % Pd/C) efficiently catalyzes the (retro‐)Michael addition of activated methylene compounds 2a – d , such as malononitrile ( 2b ), to mono‐ and doubly activated styrenes 1a – h to give the adducts 3a – l . The scope and limitations are described. The Knoevenagel condensation reaction of benzaldehyde and 2b or ethyl cyanoacetate ( 2c ) is also catalyzed by 10 % Pd/C. In these cases the Michael adducts can even be prepared in a three‐component reaction. A mechanism, with as first step the oxidative addition of 2a – d to Pd 0 , is proposed.
Cervicofacial and Cervicothoracic Rotation Flaps: An Update (2012)

Objective 1) Understand the indications for use of the cervicofacial and cervicothoracic advancement flaps in head and neck reconstruction. 2) Learn the surgical technique for constructing cervicofacial and cervicothoracic advancement flaps in head and neck reconstruction. 3) Describe the varying defects that can be reconstructed with cervicofacial and cervicothoracic advancement flaps. Method Retrospective review of medical records at a university‐based head and neck cancer center. Patients were operated on between 2001 and 2012. Patients had varying lesions that were amenable to cervicofacial and/or cervicothroacic advancement flaps. After a thorough description of indications and defect locations, complications and flap viability were evaluated. Results Sixty‐nine patients were identified, with a mean age of 66 years. Primary or recurrent skin neoplasms made up the most common surgical indication, followed by primary parotid tumors and cervical metastases from aerodigestive tract malignancies. Defects of the cheek, orbit, periauricular region, and neck were reconstructed with cervicofacial or cervicothoracic flaps. Larger wounds required extension of the incision onto the chest wall. Other reconstructive modalities were used in 38 cases to increase tissue bulk or provide internal lining. Minor wound complications occurred in 15 patients. There was no statistically significant association between wound complications and smoking or previous radiation therapy. Conclusion Compound cervicofacial and cervicothoracic rotation flaps provide a straightforward, reliable, and efficient means to reconstruct compledefects of the face, lateral skull.
Do Compression Stockings Potentiate the Fibrinolytic Capacity of the Lower Limbs? (1989)

Patients with varicose veins and liposclerosis have been shown to have impaired fibrinolytic activity 1 . Furthermore, fibrinolytic activity is much reduced in the lower than in the upper limbs, probably due to the difference in hydrostatic pressure. After 2–10 days bed rest a significant increase in potential is observed 2 . Compression support stockings can exert 30–40 mmHg of pressure which is 50% of the normal hydrostatic pressure. Therefore does the long term use of such stockings cause a significant increase in fibrinolytic potential? Seventeen patients (10 male, 7 female; mean age 52.8 +/— 9.8 yrs) with features of liposclerosis were studied. Pre- and post-euglobulin clot lysis times (ELT) were measured in the right arm and both legs using a 10 min occlusion time. The patients contralateral leg served as the control. Sigvaris stockings were made for each patient to wear on the designated leg only. Measurements were repeated after 1 and 3 months of use with the stocking in situ and after 30 min bed rest. Patients were instructed to wear the stockings at all times during the day. There were no significant differences in the pre-occlusion values between the arm or the lower limb groups throughout the study. Lower limb post occlusion ELT values were significantly higher in both the affected limb ( p < 0.002) and the patients control limb ( p < 0.002), than in the arm. This relationship was constant throughout the study period. No significant potentiation was seen after either 1 or 3 months of use. There were no new areas of ulceration throughout the study period. Thus any clinical benefit arising from the use of compression stockings is not from potentiation of local fibrinolysis.
Peroxisome proliferator-activated receptor delta activation leads to increased transintestinal cholesterol efflux (2009)

Peroxisome proliferator-activated receptor delta (PPARdelta) is involved in regulation of energy homeostasis. Activation of PPARdelta markedly increases fecal neutral sterol secretion, the last step in reverse cholesterol transport. This phenomenon can neither be explained by increased hepatobiliary cholesterol secretion, nor by reduced cholesterol absorption. To test the hypothesis that PPARdelta activation leads to stimulation of transintestinal cholesterol efflux (TICE), we quantified it by intestine perfusions in FVB mice treated with PPARdelta agonist GW610742. To exclude the effects on cholesterol absorption, mice were also treated with cholesterol absorption inhibitor ezetimibe or ezetimibe/GW610742. GW601742 treatment had little effect on plasma lipid levels but stimulated both fecal neutral sterol excretion ( approximately 200%) and TICE ( approximately 100%). GW610742 decreased intestinal Npc1l1 expression but had no effect on Abcg5/Abcg8. Interestingly, expression of Rab9 and LIMPII, encoding proteins involved in intracellular cholesterol trafficking, was increased upon PPARdelta activation. Although treatment with ezetimibe alone had no effect on TICE, it reduced the effect of GW610742 on TICE. These data show that activation of PPARdelta stimulates fecal cholesterol excretion in mice, primarily by the two-fold increase in TICE, indicating that this pathway provides an interesting target for the development of drugs aiming at the prevention of atherosclerosis.
Transport of antimicrobial agents using peptide carrier systems: anticandidal activity of m-fluorophenylalanine-peptide conjugates (1983)

A series of di- and tripeptides containing D- and L-m-fluorophenylalanine was prepared and tested in vitro for the ability to inhibit the growth of the yeast Candida albicans. The results demonstrate that peptides containing L-m-fluorophenylalanine inhibited the growth of C. albicans with minimum inhibitory concentrations (MIC's) ranging from 0.5 to 63 micrograms/mL. The parent L-m-fluorophenylalanine and peptides containing D-m-fluorophenylalanine were inactive (MIC greater than 250 micrograms/mL) in these tests. The results of competitive antagonism studies support peptide transport mediated entry of the inhibitory peptides, followed by release of L-m-fluorophenylalanine inside the cell.
Novel antibody against low‐n oligomers of tau protein promotes clearance of tau in cells via lysosomes (2020)

Novel low-n tau oligomer specific monoclonal antibody inhibits Tau oligomerization in cells and promotes toxic tau clearance.
Results of retransplantation in individuals who received two successive cadaver kidneys. (1979)

At the Royal Victoria Hospital in Montreal, 22 patients received two successive cadaver renal transplants. The results were analysed to determine which factors have the best predictive value for success or failure in renal retransplantation. The fate of a second cadaver renal allograft was found to be about the same as the first if the initial transplant has been lost because of rejection and not technical failure. The duration of survival of the initial transplant serves as the best guide to potential outcome of retransplantation after rejection of the initial graft.
Urinary Tract Infection: New Information Concerning Pathogenesis and Management (1982)

No AccessJournal of UrologyGuest Editorial1 Dec 1982Urinary Tract Infection: New Information Concerning Pathogenesis and Management Calvin M. Kunin Calvin M. KuninCalvin M. Kunin More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)53439-4AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "Urinary Tract Infection: New Information Concerning Pathogenesis and Management." The Journal of Urology, 128(6), p. 1233 © 1982 by The American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 128Issue 6December 1982Page: 1233 Advertisement Copyright & Permissions© 1982 by The American Urological Association Education and Research, Inc.MetricsAuthor Information Calvin M. Kunin More articles by this author Expand All Advertisement PDF downloadLoading ...
Single-user detectors for multiuser channels (1988)

Optimum decentralized demodulation for asynchronous Gaussian multiaccess channels is considered. It is assumed that the receiver is the destination of the information transmitted by only one active user, and single-user detectors that take into account the existence of the other active users in the channel are obtained. The problem considered is one of signal detection in additive colored nonGaussian noise, and attention is focused on one-shot structures where detection of each symbol is based only on the received process during its corresponding interval. Particular emphasis is placed on asymptotically optimum detectors for weak interferers, for CDMA (code-division multiple-access) signature waveforms with long spreading codes, and for low background Gaussian noise level.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Stimuli‐responsive mechanical properties in polymer glasses: challenges and opportunities for defense applications (2020)

Abstract The potential utility that responsive glasses provide in the areas of aeronautics, protection and unmanned systems is reviewed in this article. The article focuses on two broad classes of stimuli, photo and thermal, to better illustrate the challenges and convey some of the potential in developing these materials for the often extreme operational environments of defense applications. Three response mechanisms are outlined to provide a range of mechanical behaviors on demand: (i) shape‐changing functionalities which locally yield or soften the material to stimulate chain mobility; (ii) bond forming (or breaking) chemistries which increase (or decrease) the stiffness of the material; and (iii) energy absorbing groups which convert the incoming stimuli into a spatially controlled heating and result in a designed softening of the material. Overall, continuing to develop responsive polymer glasses that respond rapidly and efficiently under low energy inputs will be critical for future defense applications. Published 2020. This article is a U.S. Government work and is in the public domain in the USA
O processo eletrônico frente às novas perspectivas do Direito Processual Civil brasileiro. (2011)

A vida do homem em sociedade sempre passou por transformacoes que
modificaram o comportamento do proprio homem e sua vida social. O
desenvolvimento tecnologico foi a forca motriz que impulsionou a vida do homem
contemporâneo desde a maquina a vapor ate os dias atuais com os avancos da
informatica e o acesso a internet. O Estado Democratico de Direito e especialmente
o Poder judiciario, nao ficaram a margem desse desenvolvimento, caminham de
maos dadas com a sociedade nessa nova Jornada de relacoes interpessoais que ja
no presente pode-se observar que estao cada vez mais informatizadas. O Poder
Judiciario atento aos avancos da tecnologia enxerga um novo enfoque de acesso a
justica pelos meios informaticos onde alem de aperfeicoar seus servicos tambem
amplia o acesso aos mais necessitados a uma efetiva prestacao jurisdicional. Um
procedimento judicial informatizado afeta diretamente a relacao processual, visto
que adaptacoes devem ser feitas, contudo o processo eletronico pode manter os
principios e garantias do processo civil tradicional respeitando o principio do devido
processo legal. O processo judicial eletronico tende a reduzir a burocracia
eliminando etapas desnecessarias no processo reforcando o principio da duracao
razoavel do processo. O principio da publicidade pode ser encontrado no processo
eletronico na visualizacao dos atos processuais atraves da internet, ressalvados os
casos de segredo de justica. O principio do contraditorio e da ampla defesa ha de
ser preservado, pois os advogados podem peticionar atraves dos sistemas
informatizados, contudo, se faz necessario que os sistemas de informatica
desenvolvam aponto de preservar a verdade documental e a seguranca juridica das
assinaturas eletronicas de deverao ser validadas pelo ICP-Brasil. As transicao do
processo civil no Brasil para o universo digital ja pode ser observada no processo
de execucao atraves da penhora on line, mecanismo utilizado pelo juizo que
bloqueia os valores depositados em instituicao financeira pelo devedor com a
finalidade de satisfazer o credito em favor do credor. O meio ambiente agradece
pela sustentabilidade do procedimento informatizado, visto que a economia global de
material impacta favoravelmente para o desenvolvimento da sociedade. A lei 11.419
de 2006 e um preludio ao procedimento judicial eletronico e regulamenta questoes
do processo eletronico como assinatura digital e comunicacao dos atos judiciais pelo
meio eletronico. O Anteprojeto para um Novo Codigo de Processo Civil aprovado
pelo Senado Federal adequando-se a nova realidade processual traz dispositivos
com o fito de regulamentar a pratica dos atos processuais atraves do meio
eletronico. O CNJ vem desenvolvendo um software chamado PJe com a finalidade
de informatizar o processo constituindo um desafio para a nova realidade processual
brasileira.
Impact of Facial Leakage on Respirator Efficiency: Recent Developments (2017)

When wearing a respirator is required, the wearer must pass a fit test before entering the workplace. The fit test is designed to measure the total aerosol penetration through both pathways, the filter and the faceseal leaks (referred to as a total inward leakage [TIL]). There is no standard respirator testing protocol capable of quantitatively differentiating between the two pathways under actual breathing conditions. Several earlier studies attempted to assess the relative contributions of the two pathways.
Independent and synergistic effects of disulfide bond formation, beta 2-microglobulin, and peptides on class I MHC folding and assembly in an in vitro translation system (1992)

We have examined the post-translational processing, intrachain disulfide bond formation, folding, and assembly of MHC class I H chains with beta 2-microglobulin after coupled in vitro translation of homogeneous mRNA and transport of nascent chains into canine microsomal vesicles. The formation of native alpha 3 domain conformation was dependent on conditions that optimized intrachain disulfide bond formation, and efficient folding of the alpha 1 alpha 2 domain required exposure to antigenic peptide. beta 2-microglobulin and peptide acted synergistically in forming native alpha 1 alpha 2 domain structure, and a small proportion of molecules with native alpha 1 alpha 2, but non-native alpha 3 structure were detected, indicating that alpha 3 domain folding is not an absolute prerequisite for the formation of native alpha 1 alpha 2 domain structure.
Spontaneous and stimulated Raman scattering measurements in KDP crystal segments, and benzene (1984)

Transverse stimulated Raman scattering (SRS) within KDP crystal segments and index-matching fluids are potential limitations on Nova harmonic conversion array design and performance. We have developed an overall picture of the anisotropic Raman scattering behavior of KDP from a large set of spontaneous and stimulated measurements.
Methylcellulose prevents the regression of carbon tetrachloride‐induced liver fibrosis and cirrhosis in rats (1990)

Male F344 rats were treated with carbon tetrachloride (CCl4; 0.3 ml/kg per os, 3 times a week) for 2 mo. At the end of the CCl4 administration out of the 65 animals 30 received methylcellulose (MCL; 3.85 ml/kg, 5% solution, per os, 3 times a week) for 6 wk. Thirty-five rats did not receive any further treatment. The fibrotic change caused by CCl4 reached its maximum 2 wk after the end of the treatment. After this, the severity of the fibrotic change regressed spontaneously. This regression was not observable in the liver of rats that received MCL. The fact that MCL is used as a solvent for drugs and as a food additive underlines the importance of the effect of this compound on chronic liver injury.
Overcoming Problems Incorporating NMR into the Organic Chemistry Lab (2013)

Organic chemistry laboratory courses present exceptional opportunities to teach students how to utilize NMR to its fullest potential. When implementing experiments that use NMR to analyze products in the undergraduate teaching lab a number of practical problems arise, even with the use of an automated instrument. The pertinent issues in our situation involve sample submission timing, data transfer, and spectra processing. This chapter addresses what can be done to alleviate those problems using a newly designed experiment incorporating flow hydrogenation that has been incorporated into our organic laboratory sequence. Solutions include having a teaching assistant present by the NMR spectrometer room as students are submitting their samples, using Dropbox as a versatile approach to distributing and accessing data, and that iNMR reader is a flexible solution for students to process their data.
The oxygen balance criterion for thermal hazards assessment (1995)

Abstract It is a matter of considerable practical importance to recognize metastable, potentially hazardous chemical compositions so that suitable thermal hazard management means can be provided as a part of process safety management. This communication is a report on our evaluation of the oxygen balance criterion as a screening technique for thermal hazard assessment.
Chlorine hazard evaluation for the zinc-chlorine electric vehicle battery. Final technical report. [50 kWh] (1980)

Hazards associated with conceivable accidental chlorine releases from zinc-chlorine electric vehicle batteries are evaluated. Since commercial batteries are not yet available, this hazard assessment is based on both theoretical chlorine dispersion models and small-scale and large-scale spill tests with chlorine hydrate (which is the form of chlorine storage in the charged battery). Six spill tests involving the chlorine hydrate equivalent of a 50-kWh battery indicate that the danger zone in which chlorine vapor concentrations intermittently exceed 100 ppM extends at least 23 m directly downwind of a spill onto a warm (30 to 38/sup 0/C) road surface. Other accidental chlorine release scenarios may also cause some distress, but are not expected to produce the type of life-threatening chlorine exposures that can result from large hydrate spills. Chlorine concentration data from the hydrate spill tests compare favorably with calculations based on a quasi-steady area source dispersion model and empirical estimates of the hydrate decomposition rate. The theoretical dispersion model was combined with assumed hydrate spill probabilities and current motor vehicle accident statistics in order to project expected chlorine-induced fatality rates. These calculations indicate that expected chlorine fataility rates are several times higher in a city such as Los Angeles with a warm and calm climate than in a colder and windier city such as Boston. Calculated chlorine-induced fatality rate projections for various climates are presented as a function of hydrate spill probability in order to illustrate the degree of vehicle/battery crashworthiness required to maintain chlorine-induced fatality rates below current vehicle fatality rates due to fires and asphyxiations. 37 figures, 19 tables.
Presence of pleural adhesions can predict conversion to thoracotomy and postoperative surgical complications in patients undergoing video-assisted thoracoscopic lung cancer lobectomy (2018)

Presence of pleural adhesions can predict conversion to thoracotomy and postoperative surgical complications in patients undergoing VATS lobectomy for NSCLC. Our study calls for an internationally accepted grading system for the presence of pleural adhesions to stratify the surgical risk.
A Review of: “ORGANOTIN COMPOUNDS: NEW CHEMISTRY AND APPLICATIONS. J. J. Zuckerman, Editor, American Chemical Society, Washington, D. C., 1976, 299 pp., $32.50” (1977)

(1977). A Review of: “ORGANOTIN COMPOUNDS: NEW CHEMISTRY AND APPLICATIONS. J. J. Zuckerman, Editor, American Chemical Society, Washington, D. C., 1976, 299 pp., $32.50”. Synthesis and Reactivity in Inorganic and Metal-Organic Chemistry: Vol. 7, No. 4, pp. 395-397.
Influence of Circumferential Tread Pattern Stiffness on Tire Road Noise Generation under Driving Torque (2014)

Concerning the sound emission of electric vehicles there are two main challenges: On the one hand, the exterior noise is on a very low noise level and approaching electric vehicles might not be recognized in city traffic. On the other hand, compared to internal combustion engines, electric drives develop a considerably high torque from the standstill which might increases tire road noise of about 10 dB in the near-field. Since combustion engine noise gets eliminated, tire road noise will not be masked anymore during acceleration but instead occurs as a disturbing, dominant acoustic source. The paper describes first an inner drum test rig which allows the reproducible measurement of tire road noise on real road surfaces at driving and braking torque. Then, test results of special tires with different rubber compounds and pattern designs are presented. The influence of pattern stiffness and tire torque on tire road noise generation is analysed. Additional the inner drum test results were validated by pass-by measurements on different road surfaces. Finally, the effects and mechanisms of the noise phenomena are discussed and tire pattern design concepts for low noise emission under driving torque are derived.
Parallax - A New Operating System Prototype Demonstrating Service Scaling and Service Self-Repair in Multi-core Servers (2011)

This paper describes a prototype demonstrating a new operating system (called Parallax) for the new generation many-core servers. The operating system is designed to address scaling, resource monitoring, dynamic configuration, and self-repair of many-core chip based servers to support distributed computational tasks. The operating system is implemented in assembler language for efficiency and supports C/C++ programming interfaces for high-level programming. The Parallax operating system is based on the DIME network computing model supporting distributed network-centric computing architecture. A parallel signaling network overlay over a network of von Neumann stored program control (SPC) computing nodes is utilized to implement dynamic fault, configuration, accounting, performance, and security management of both the nodes and the network based on business priorities, workload variations and latency constraints.