gebhart/patrepeval huggingface dataset:
Urinary Markers of Adrenarche: Reference Values in Healthy Subjects, Aged 3–18 Years (2005)

Information on the urinary excretion of dehydroepiandrosterone (DHEA) and its direct metabolites is scarce for healthy subjects during growth. We used gas chromatography-mass spectrometry urinary steroid profiling to noninvasively study adrenarchal metabolome in 400 healthy subjects, aged 3-18 yr. Urinary 24-h excretion rates of DHEA did not increase significantly before age 7-8 yr. However, DHEA together with its 16alpha-hydroxylated downstream metabolites, 16alpha-hydroxy-DHEA and 3beta,16alpha,17beta-androstenetriol (DHEA&M), as well as the DHEA metabolite, 5-androstene-3beta,17beta-diol (ADIOL), and the sum of major urinary androgen metabolites (C19) rose consistently from the youngest to the oldest age group. The significant increases (P < 0.01) observed for 24-h excretion rates of C19, ADIOL, and DHEA&M were 2- to 4-fold in boys and girls between age 3 and 8 yr. DHEA&M, for example, rose from about 20 to 80 microg/d (P < 0.0001) during this period. Until the age of 16 yr, DHEA&M excretion also increased to nearly 1000 microg/d. Patterns of steroidogenic enzyme activities were assessed (from definite ratios of urinary steroid metabolites) for 21-hydroxylase, 3beta-hydroxysteroid dehydrogenase, 17beta-hydroxysteroid dehydrogenase, and 5alpha-reductase. Our results indicate for healthy boys and girls that adrenarche is a gradual process starting much earlier than hitherto believed. Efficient metabolism of DHEA, especially to 16-hydroxylated steroids, may explain the almost constant levels seen for this steroid until age 7-8 yr. The established reference values for DHEA, DHEA&M, ADIOL, C19 (including androsterone and etiocholanolone), and urinary parameters of steroidogenic enzyme activities could be useful to identify nutritional, environmental, and pathophysiological interrelations with the progressive maturational process of adrenarche. Our data may also be used as reference data for the diagnosis of steroid-related disorders.
Narrow 87Rb hyperfine-structure resonances in an evacuated wall-coated cell (1982)

Examination of 87Rb δF = 1, δ‖mF‖ = 1 hyperfine resonances in a 200-cm3 evacuated tetracontane wall-coated Pyrex cell which has been sealed since 1968 shows remarkable Dicke-narrowed sub-Doppler Lorentzian line shapes with less than 11 Hz full width. This linewidth is 70 times narrower than that in buffer gas filled cells used in commercial Rb atomic frequency standards. The phase shift per wall collision is 0.058 radians/collision as derived from an observed wall-induced hyperfine frequency shift of −52 Hz at a wall temperature of 26 °C.
TV프로그램에 따른 방송인(放送人)의 이미지 메이킹에 영향(影響)을 미치는 요인(要因) -TV분장(扮裝), 헤어, 의상(衣裳)을 중심(中心)으로- (2010)

The purpose of this study is to examine possible factors affecting the image making of telecaster in TV program on the basis of makeup, hair styling and costume, so that it could provide basic materials for broadcast staffs in broadcast fine arts, and help them to produce ideal broadcast programs. The findings of this study can be outlined as follows: First, according to the analysis on possible associations between makeup and telecaster`s image making, makeup coordinators thought that depending on program, broadcast makeup is different from common makeup in the aspect of technique and style, and valued face type, eyebrow and eye shape in the aspect of face profile as a makeup factor. Second, according to analysis on possible relations between hair styling and telecaster`s image making, it was found that some hair styling factors were considered critical(e.g. face type, hair length, hair color and hair wave). Third, according to analysis on possible associations between costume and telecaster`s image making, it was found that face type, stature, weight, costume color and style were considered important in terms of costume factors. Fourth, according to analysis on telecaster`s awareness about the importance of makeup, hair styling and costume, it was found that telecasters valued all the 3 factors, independent of program type. Fifth, in view of telecaster`s images depending on program, the analysis on telecaster`s images broadcast staffs pursue showed that most ideal anchor images included reliability, intellect, approachability, sophistication, faithfulness, warm-heartedness, confidence and high culture.
Comments on a Meta-analysis of the Relation between Dietary Calcium Intake and Blood Pressure (1998)

The role of dietary calcium in the etiology of hypertension is controversial. In 1995, Cappuccio et al. (American Journal of Epidemiology,1995;142:935-45) examined this issue in a meta-analysis of observational studies published between 1983 and 1993. The author of the present paper reviewed the original studies underlying this meta-analysis and discovered that data from one study had been inappropriately extracted and converted, leading to an understatement of the calcium-blood pressure relation by a factor of about 30. This review also raised questions about the extraction and conversion of data from several other studies and about the statistical methods used. The author repeated the meta-analyses and discovered an unadjusted regression slope between dietary calcium and systolic blood pressure of -0.34 mmHg/100 mg per day (95% confidence interval (CI) -0.46 to -0.22) for men, -0.15 mmHg/100 mg per day (95% CI -0.19 to -0.11) for women, and -0.39 mmHg/100 mg per day (95% CI -0.47 to -0.31) for men and women. For diastolic blood pressure, the pooled regression slope for men was -0.22 mmHg/100 mg per day (95% CI -0.32 to -0.13), while for women it was -0.051 mmHg/100 mg per day (95% CI -0.090 to -0.012); for men and women it was -0.35 mmHg/100 mg per day (95% CI -0.67 to -0.02). These slopes are still modest but are larger than those reported in the original analysis. However, since all of these analyses were based on zero-order correlations or regressions, extreme caution must be exercised in interpreting the results.
Present and Future of Synchronization in the US Telephone Network (1987)

The need for phase (timing) control in a digital network is described. Because of unknown and unstable path delays, phase con- trol is done on a local basis, whereas only frequency control is feasible on a global basis. The means to provide frequency control is potentially built into the network as a hierarchical masterislave system. The char- acteristics of the four levels of quality of the frequency sources (clocks) in this system are described. Each clock must be phase-locked to a clock of equal or better quality (e.g., S-3 locked to S-2). The pull-in range of the phase-lock loop associated with a clock must allow for inaccuracies of the clock to which it locks-even under startup condi- tions. The pull-in range for an S-3 clock expressed on a fractional fre- quency basis is about 9 X The importance of this number is placed in perspective by realizing two things: 1) the goal for frequency accu- racy of a signal controlling an S-3 clock is a minimum of 3.5 X 2) it is the current intention to equip about 98 percent of the 10 000 digital switches with S-3 clocks. This means that almost all S-3 clocks will be directly connected to an S-3, not an S-2, clock. Furthermore, many other types of equipment, such as digital cross connects and dig- ital channel banks (based on S-3 or S-4 clocks), will intentionally or inadvertently become sources of timing signals. The magnitude of the potential problem therefore becomes apparent. Experience in the field indicates that the number of instances of synchronization problems to- day is troublesomely large. The three major causes of these problems- equipment and line failures, design errors, and operational errors- are discussed. Means of limiting these problems, including the greater use of high-quality equipment and better system monitoring, are also discussed.
Digital PDL Compensation in 3D Stokes Space (2013)

A Stokes space based technique for digital polarization-dependent losses (PDL) monitoring and compensation is proposed. The channel PDL monitoring is carried out with a resolution of 0.15 dB by computing the mean point of the signal samples represented in the three-dimensional Stokes space. The presented compensation technique is based on rotations and translations of the signal samples in the Stokes space, and provides a PDL compensation up to 2.5 dB. Error vector magnitude results show a gain of about 3 dB (assuming a PDL value equal to 1.5 dB) to a Stokes space based polarization demultiplexing technique without PDL compensation.
Auditory competence in early life : the roots of communicative behavior (1976)

These results revealed that the mutation state of the BCR signaling pathway has potential as a biomarker to predict the efficacy of ICIs in LUAD.
Proton relaxation times in cancer diagnosis (1988)

Proton nuclear magnetic resonance relaxation parameters (T1, T2) were measured for over 100 malignant and normal tissue samples of various organs of the human body. The purpose of this study was to estimate the reliability of the NMR technique in discriminating normal from malignant tissues. Breast and cervix samples were analyzed by using the malignancy index concept and we were able to distinguish malignant and normal tissue in 17 out of 18 breast samples and 5 out of 7 cervix samples. Since the relaxation data of a normal control population of the other organs were not available, the data for these are reported without any further analysis. The distinction between carcinomas and sarcomas was also made by using the estimated relaxation parameters. Malignancy indices of breast tissue samples for linear least-squares and nonlinear two-parameter and three-parameter least-squares procedures were calculated and used to evaluate the relative efficiencies in discriminating malignant from normal tissues.
Lightweight SOA-based twin-engine architecture for enterprise systems in fixed and mobile environments (2016)

Mobile devices as a popular computing platform for enterprise systems have enabled certain tasks to be executed out of office. However, the work may be interrupted due to the server shutdown or network disconnection when employees access traditional single-engine Business Process Management System. To overcome this defect, we present a lightweight twin-engine architecture based on Service Oriented Architecture (SOA). In this paper, we discuss in detail the design and implementation of the architecture, and present a trigger mechanism to activate engines according to the states of hybrid environments since it is critical for the two types of engines to cooperate closely in hybrid environments with fixed and mobile computing resources. The experimental results validate the usability of the architecture.
The Squarehead and the Square (2005)

Corporal Long told me that when the Squarehead applied for enlistment at the Baltimore Recruiting Office he was so unsophisticated that they had to lash him to a bunk and blindfold him before they could get leather shoes on him. Major Kelly, "The Colonel" of Salmagundi days, was the recruiting officer that accepted the latest immigrant from Schleswig, and thereby wove for himself a crown of thorns.
APLICAÇÃO DE COAGULANTE NATURAL E DE COAGULANTE QUÍMICO NO TRATAMENTO DE EFLUENTES TEXTEIS (2016)

Nas ultimas decadas, o setor agricola e industrial tem passado por constante crescimento e com isso, os problemas ambientais tem se tornado cada vez mais, criticos e frequentes. O setor textil e marcante no quesito contaminacao, visto que alem de comporem grandes parques industriais instalados, os mesmos geram grandes volumes de efluentes, os quais, quando nao corretamente tratados, podem causar serios problemas de contaminacao ambiental (KUNZ et al., 2002).
Ionic Liquids as Demulsifiers of Water-in-Crude Oil Emulsions: Study of the Microwave Effect (2010)

Water/oil emulsions are formed in oil wells because of the presence of natural surfactants, such as asphaltenes and resins. These molecules strongly stabilize the water/oil interface and prevent coalescence of water droplets. Because water/oil phase separation is necessary before oil refining, surfactants are used to break water/oil emulsions. Herein, surface-active ionic liquids were synthesized and evaluated for the first time as demulsifier agents for water-in-crude oil emulsions of light, heavy, and ultra-heavy Mexican crude oil under conventional and microwave dielectric heating. The use of microwave irradiation accelerated and increased significantly the efficiency of demulsification of ultra-heavy crude oil emulsion.
A Study on Increase of Sulfur Hexafluoride(SF<sub>6</sub>) Destruction and Removal Efficiency by Conditioning Agent(H<sub>2</sub>) (2012)

Destruction and removal efficiency (DRE) of <TEX>$SF_6$</TEX> was tested with low degrees of ionization. The applied dose of ionization energy varied from 63.70 to 212.34 kGy. The initial concentration and flow rate of <TEX>$SF_6$</TEX> gas were 1,000 ppm and 50L/min, respectively. In order to increase the DRE, injection of conditioning agent (<TEX>$H_2$</TEX>) were conducted. The DRE of <TEX>$SF_6$</TEX> increased about 2 times with injection of <TEX>$H_2$</TEX> gas.
Gentian Violet — Is It Safe? (1990)

EDITORIAL COMMENT: Yet another old friend seems to have become a potential enemy. Because of the evidence reviewed in this report, many paediatricians no longer prescribe gentian violet for infants with evidence of candidial infection of buccal mucosa or buttocks. Whether or not the gynaecologist should discontinue the practice of using a single application of gentian violet (1/2 % aqueous) at the time of diagnosis of severe thrush infection of the vagina, while the speculum remains in position, is uncertain; although immediate relief of itch and discomfort is guaranteed, a dose of a specific antifungal preparation, perhaps one of the single‐dose treatments (isoconazole pessaries 2 × 300mg or clotrimazole pessaries 500mg), could be used in the same manner.
Melhoramento do cafeeiro XV: variabilidade observada em progênies de café (1959)

As análises das produções de cafeeiros constituintes de diversas progênies, principalmente de café Bourbon Vermelho, com produções controladas por 12 a 15 anos. mostraram acentuada variabilidade na produção, o mesmo ocorrendo entre cafeeiros F1 derivados de hibridações entre plantas selecionadas. A fim de avaliar as causas dessa variação foram escolhidas, em quatro progenies S1 e em três híbridos F1, cafeeiros com as mais altas e as mais baixas produções, bem como uma planta em cada progênie com produção correspondente à classe mediana, a fim de servirem de plantas matrizes para derivação de progênies correspondentes às gerações S2 e F2. Estas foram plantadas, em 1953, em um ensaio comparativo, onde também foram incluídas novas progenies S1 e F1 dos mesmos cafeeiros, bem como progênies selecionadas de outras variedades comerciais como Bourbon Amarelo e Mundo Novo. A análise dos resultados das quatro primeiras produções (1955 a 1958) bem como da altura e vigar dos cafeeiros indicou, em todos os conjuntos de progênies examinadas, que a grande variação observada entre as plantas de uma mesma progênie de Bourbon é principalmente devida a influências do ambiente, desde que não se notaram diferenças na produção das progênies S2 e F2 derivadas de plantas S1 e F1 com as mais altas e as mais baixas produções. A mesma condição se verificou em relação à altura das plantas. Os valores das variâncias da produção para as progênies S1 e S2 em cada grupo de progenies não indicaram nenhum efeito específico da autofecundação, reduzindo-os ou aumentando-os. Nas gerações F2 as variâncias se mostraram mais uniformes, porém as diferenças entre as variâncias das gerações F1 e F2 não foram significativas. Pode-se concluir dos dados dêste ensaio que a seleção do café Bourbon Vermelho deve ser baseada na produção média das progenies e que a seleção dentro da progênie não conduz a nenhum progresso. Os dados também explicam o motivo da baixa correlação freqüentemente verificada entre a produção das plantas matrizes e de suas respectivas progênies. O estudo comparativo de todos os tratamentos mostrou a existência de uma razoável correlação entre o bom aspecto vegetativo e a produtividade das progênies. Notou-se. também, que o Mundo Novo é realmente bastante produtivo, o que confirma os resultados já obtidos sobre o valor econômico dessa variedade comercial de café.
HYDRODYNAMIC RESEARCH ON BOX-TYPE AMPHIBIANS. (1966)

Model tests are described for reducing the hydrodynamic drag and swamping of an amphibian. The investigation shows appreciable speed increases and elimination of swamping are possible. (Author)
Hyperspectral imagery: clutter adaptation in anomaly detection (2000)

Hyperspectral sensors are passive sensors that simultaneously record images for hundreds of contiguous and narrowly spaced regions of the electromagnetic spectrum. Each image corresponds to the same ground scene, thus creating a cube of images that contain both spatial and spectral information about the objects and backgrounds in the scene. In this paper, we present an adaptive anomaly detector designed assuming that the background clutter in the hyperspectral imagery is a three-dimensional Gauss-Markov random field. This model leads to an efficient and effective algorithm for discriminating man-made objects (the anomalies) in real hyperspectral imagery. The major focus of the paper is on the adaptive stage of the detector, i.e., the estimation of the Gauss-Markov random field parameters. We develop three methods: maximum-likelihood; least squares; and approximate maximum-likelihood. We study these approaches along three directions: estimation error performance, computational cost, and detection performance. In terms of estimation error, we derive the Cramer-Rao bounds and carry out Monte Carlo simulation studies that show that the three estimation procedures have similar performance when the fields are highly correlated, as is often the case with real hyperspectral imagery. The approximate maximum-likelihood method has a clear advantage from the computational point of view. Finally, we test extensively with real hyperspectral imagery the adaptive anomaly detector incorporating either the least squares or the approximate maximum-likelihood estimators. Its performance compares very favorably with that of the RX algorithm.
Accessibility of chromosomal recombination breaks in nuclei of wild-type and DNA-PKcs-deficient cells (2009)

V(D)J recombination is a highly regulated process, proceeding from a site-specific cleavage to an imprecise end joining. After the DNA excision catalyzed by the recombinase encoded by recombination activating genes 1 and 2 (RAG1/2), newly generated recombination ends are believed held by a post-cleavage complex (PC) consisting of RAG1/2 proteins, and are subsequently resolved by non-homologous end joining (NHEJ) machinery. The relay of these ends from PC to NHEJ remains elusive. It has been speculated that NHEJ factors modify the RAG1/2-PC to gain access to the ends or act on free ends after the disassembly of the PC. Thus, recombination ends may either be retained in a complex throughout the recombination process or left as unprotected free ends after cleavage, a condition that may permit an alternative, non-classical NHEJ end joining pathway. To directly test these scenarios on recombination induced chromosomal breaks, we have developed a recombination end protection assay to monitor the accessibility of recombination ends to exonuclease-V in intact nuclei. We demonstrate that these ends are well protected in the nuclei of wild-type cells, suggesting a seamless cleavage-joining reaction. However, divergent end protection of coding versus signal ends was found in cells derived from severe combined immunodeficient (scid) mice that are defective in the catalytic subunit of DNA-dependent protein kinase (DNA-PKcs). While signal ends are resistant, opened coding ends are susceptible to enzymatic modification. Our data suggests a role of DNA-PKcs in protecting chromosomal coding ends. Furthermore, using recombination inducible scid cell lines, we demonstrate that conditional protection of coding ends is inversely correlated with the level of their resolution, i.e., the greater the accessibility of the coding ends, the higher level of coding joints formed. Taken together, our findings provide important insights into the resolution of recombination ends by error-prone alternative NHEJ pathways.
Comprehensive Insights into the Multi-Antioxidative Mechanisms of Melanin Nanoparticles and Their Application To Protect Brain from Injury in Ischemic Stroke (2016)

Nanotechnology-mediated antioxidative therapy is emerging as a novel strategy for treating a myriad of important diseases through scavenging excessive reactive oxygen and nitrogen species (RONS), a mechanism critical in disease development and progression. However, similar to antioxidative enzymes, currently studied nanoantioxidants have demonstrated scavenging activity to specific RONS, and sufficient antioxidative effects against multiple RONS generated in diseases remain elusive. Here we propose to develop bioinspired melanin nanoparticles (MeNPs) for more potent and safer antioxidative therapy. While melanin is known to function as a potential radical scavenger, its antioxidative mechanisms are far from clear, and its applications for the treatment of RONS-associated diseases have yet to be well-explored. In this study, we provide for the first time exhaustive characterization of the activities of MeNPs against multiple RONS including O<sub>2</sub><sup>•-</sup>, H<sub>2</sub>O<sub>2</sub>, <sup>•</sup>OH, <sup>•</sup>NO, and ONOO<sup>-</sup>, the main toxic RONS generated in diseases. The potential of MeNPs for antioxidative therapy has also been evaluated in vitro and in a rat model of ischemic stroke. In addition to the broad defense against these RONS, MeNPs can also attenuate the RONS-triggered inflammatory responses through suppressing the expression of inflammatory mediators and cytokines. In vivo results further demonstrate that these unique multi-antioxidative, anti-inflammatory, and biocompatible features of MeNPs contribute to their effective protection of ischemic brains with negligible side effects.
Improved slotted-filter for over-mode rectangular waveguide (2002)

A slotted-mode filter with high handling power for over-mode rectangular waveguide is described in this paper, however, because the unwanted higher modes TE/sub mn/ and TM/sub mn/ are degenerate in the system, they cannot be removed completely. The situation can be improved by deforming slightly the cross-sectional shape of the filter.
Atlas of Cardiothoracic Surgery (1990)

Atlas of cardiothoracic surgery , Atlas of cardiothoracic surgery , کتابخانه دیجیتال جندی شاپور اهواز
Optical display device using bistable electrets (1977)

The bistable mechanical motion of a corona-charged polypropylene film in the electric field developed between two electrodes is used in the construction of a new transmission light gate. The minimum switching voltage and time are, respectively, 500 V and 50 ms, in accordance with the proposed motion model. Optical and electrical characteristics of an electret display device using a 5×3 array of light gates are presented.