gebhart/patrepeval huggingface dataset:
L-selectin expression differentiates T cells isolated from different lymphoid tissues in cattle but does not correlate with memory. (1992)

L-selectin (LECAM-1, LAM-1) was expressed by a high proportion of CD4+ and CD8+ T cells, as well as almost all of the gamma delta T-cell receptor (TcR)+ (WC1+) T cells, isolated from blood, lymph nodes or tonsils. CD4+ T cells in the lamina propria of the gut villi and CD8+ T cells in the villous epithelium as well as the majority of WC1+ T cells in the gut mucosa were L-selectin-. The proportion of T cells from Peyer's patches that synthesized the molecule was intermediate between the value for blood and gut mucosa. Expression of L-selectin therefore marks T cells in cattle with a distinct tissue distribution that correlates with its function as the peripheral node homing receptor. The proportion of CD4+ and CD8+ T cells in the circulation that were L-selectin+ decreased with age. Unlike CD45R, expression of L-selectin was not related to CD4 T-cell memory as judged by proliferation in transformation assays to soluble antigen. Three-colour immunofluorescent staining demonstrated four subpopulations of CD4 and CD8 T lymphocytes in peripheral blood mononuclear cells (PBMC) that were CD45R+, L-selectin+; CD45R+, L-selectin-; CD45R-, L-selectin+; CD45R-, L-selectin-. CD4(4) memory cells were CD45R- and L-selectin+ or L-selectin-. Taken with earlier studies the reported observations demonstrated that only one of the four phenotypes of the CD4+ T cells in blood is present in the lamina propria of the gut villi and these are CD45R-, L-selectin-. Two of the four phenotypes of CD8+ T cells were present in the gut epithelium; these were CD45R+, L-selectin- or CD45R-, L-selectin-. Expression of the bovine molecule was not rapidly down-regulated on T cells following activation by exposure to phorbol myristate acetate.
Novel Prediction Framework for Path Delay Variation Based on Learning Method (2020)

Path delay variation becomes a serious concern in advanced technology, especially for multi-corner conditions. Plenty of timing analysis methods have been proposed to solve the issue of path delay variation, but they mainly focus on every single corner and are based on a characterized timing library, which neglects the correlation among multiple corners, resulting in a high characterization effort for all required corners. Here, a novel prediction framework is proposed for path delay variation by employing a learning-based method using back propagation (BP) regression. It can be used to solve the issue of path delay variation prediction under a single corner. Moreover, for multi-corner conditions, the proposed framework can be further expanded to predict corners that are not included in the training set. Experimental results show that the proposed model outperforms the traditional Advanced On-Chip Variation (AOCV) method with 1.4X improvement for the prediction of path delay variation for single corners. Additionally, while predicting new corners, the maximum error is 4.59%, which is less than current state-of-the-art works.
Development of Nickel and Nickel-Iron Aluminides for Elevated-Temperature Structural Use (1988)

This paper summarizes recent work on alloy design of Ni3Al alloys for structural use at elevated temperatures. Efforts on alloy development have been focused on four areas: (1) improvement of ductility at ambient temperatures, (2) enhancement of high-temperature strength by solid-solution effects, (3) alleviation of dynamic embrittlement in oxidizing environments, and (4) fabrication improvement. Nickel aluminides with promising properties have been developed by microalloying with boron and macroalloying with chromium, zirconium (or hafnium), and iron additions.
Nachrichtenübertragung (2004)

Vorwort zur dritten Auflage Die erste Auflage dieses Lehrbuchs erschien vor nunmehr zwölf Jahren. Während dieser Zeit hat sich die moderne Multimedia-Landschaft dramatisch verändert - wesentliche neue
Sp3 Represses Transcription When Tethered to Promoter DNA or Targeted to Promoter Proximal RNA (1996)

Sp3 is a member of the Sp family of transcription factors, and it binds to the GC box with an affinity and specificity comparable with that of Sp1. Previous studies have shown that Sp3 repressed Sp1-mediated transcriptional activation, suggesting that Sp3 is an inhibitory member of the Sp family. The experiments described here demonstrate that Sp3 contains a portable repression domain that can function independently from the zinc finger DNA-binding domain. We found that the amino-terminal region of Sp3 tethered to a promoter DNA by connecting to a heterologous DNA-binding protein domain represses transcriptional activation by different positive regulators. Moreover, we determined that Sp3 targeted to a promoter-proximal RNA sequence acts as a transcriptional repressor. Taken together, our results suggest that Sp3 functions as a repressor by protein-protein interaction with components of the general transcription complex.
The human entorhinal cortex: A cytoarchitectonic analysis (1995)

The entorhinal cortex of man is in the medial aspect of the temporal lobe. As in other mammalian species, it constitutes an essential component of the hippocampal formation and the route through which the neocortex interacts with the hippocampus. The importance of knowing its architecture in detail arises from the possibility of extrapolating it to experimental findings, notably in the nonhuman primate. We have investigated the cytoarchitectonic features of the human entorhinal cortex by using as a base our previous study (D.G. Amaral, R. Insausti, and W.M. Cowan [1987] J. Comp. Neurol. 264:326-355) of the nonhuman primate entorhinal cortex. We prepared serial sections of the temporal lobe from 35 normal brains. Thionin- and myelin-stained series were made of all cases. Sections spaced 500 microns apart through the full rostrocaudal extent of the entorhinal cortex were analyzed. The human entorhinal cortex is made up of six layers, of which layer IV does not appear throughout all subfields of the entorhinal cortex. The overall appearance resembles that of the adjacent neocortex in lateral and caudal portions. In harmony with general structural principles in the nonhuman primate entorhinal cortex, our analysis supports the partitioning of the human entorhinal cortex into eight different subfields. (1) The olfactory subfield (EO), the rostralmost field, is little laminated. (2) The lateral rostral subfield (ELr), laterally located, merges with the laterally adjacent perirhinal cortex. (3) The rostral subfield (ER) is between EO and ELr, with better differentiation of layers II and III than EO. (4) The medial intermediate subfield (EMI) is located at the medial border. (5) The intermediate field (EI) is a lateral continuation of EMI; lamina dissecans (layer IV) can be best appreciated in this field. (6) The lateral caudal subfield (ELc) laterally borders on EI as a continuation of ELr. (7) The caudal subfield (EC) lies caudal to the beginning of the hippocampal fissure, with a distinctive, clear space (Vc) between layers V and VI. (8) The caudal limiting field (ECL) forms the caudal termination of the entorhinal cortex. Thus our parcellation of the entorhinal cortex in man is largely parallel to that arrived at in the monkey. This close homology provides a rational basis for the application to clinical problems of anatomical and functional information obtained in experimental work in nonhuman primates.
A note on the immunogenicity of ultra-violet irradiated vaccinia virus in man (1962)

A preparation of vaccinia virus inactivated by ultra-violet irradiation under strictly controlled conditions, and shown to produce neutralizing antibody and resistance to challenge in rabbits, was active in only about half of 37 human volunteers. It was not, therefore, likely to be usefully immunogenic in man. In the largest single test, 15 of 25 men had unmodified primary skin reactions when challenged with living virus, although five of these had circulating antibody. On the other hand, only three of 10 men who responded to challenge with modified or negative reactions, had no circulating antibody. In man the presence of circulating antibody does not necessarily indicate resistance to infection in the skin, nor does skin immunity always indicate the presence of circulating antibody.
MDA-based approach for embedded software generation from a UML/MOF repository (2006)

This work presents a UML/MOF meta-modeling infrastructure, following the MDA approach, which is oriented to the design space exploration of embedded systems, based on the independent specification of application and platform. A mapping from the application into the platform is implemented by model transformations. A meta-data repository implementation is also introduced, automatically providing an Application Programming Interface (API) that is suitable to the manipulation of the UML meta-models and models and to the implementation of design tools for embedded systems. In order to illustrate the applicability of these resources, a source code generation tool for embedded software has been implemented and applied in a concrete case study.
Chain Ownership and Long-Term Health Care Facility Performance (1986)

The increase in the number of chain-affiliated facilities is causing major structural change in the long-term health care industry. In order to assess the impact of chain ownership on performance, a sample of 265 skilled nursing facilities is analyzed using data from the 1977 National Nursing Home Survey. Descriptive analysis indicates differences in facihty costs and characteristics related to chain ownership. Multiple regression analysis indicates that once facility characteristics are controlled for, no further significant cost differences attributable to chain affiliation are found. Implications of the empirical results are discussed.
iPAWS: Instruction-issue pattern-based adaptive warp scheduling for GPGPUs (2016)

Thread or warp scheduling in GPGPUs has been shown to have a significant impact on overall performance. Recently proposed warp schedulers have been based on a greedy warp scheduler where some warps are prioritized over other warps. However, a single warp scheduling policy does not necessarily provide good performance across all types of workloads; in particular, we show that greedy warp schedulers are not necessarily optimal for workloads with inter-warp locality while a simple round-robin warp scheduler provides better performance. Thus, we argue that instead of single, static warp scheduling, an adaptive warp scheduler that dynamically changes the warp scheduler based on the workload characteristics should be leveraged. In this work, we propose an instruction-issue pattern-based adaptive warp scheduler (iPAWS) that dynamically adapts between a greedy warp scheduler and a fair, round-robin scheduler. We exploit the observation that workloads that favor a greedy warp scheduler will have an instruction-issue pattern that is biased towards some warps while workloads that favor a fair, round-robin warp scheduler will tend to issue instructions across all of the warps. Our evaluations show that iPAWS is able to adapt to the more optimal warp scheduler dynamically and achieve performance that is within a few percent of the statically determined, more optimal warp scheduler. We also show that iPAWS can be extended to other warp schedulers, including the cache-conscious wavefront scheduling (CCWS) and Memory Aware Scheduling and Cache Access Re-execution (MASCAR) to exploit the benefits of other warp schedulers while still providing adaptivity in warp scheduling.
Sterile Culture of Rotylenchulus reniformis on Tomato Root with Gellan Gum as a Supporting Medium. (1991)

Rotylenchulus reniformis was repeatedly propagated in sterile excised tomato roots growing on modified White's medium with gellan gum as the support. Gellan gum provided an optically clear support medium that could be liquified by adding 5 mM disodium ethylenediaminetetraacetate (EDTA) to facilitate nematode extraction. Liquefaction of the gellan-gum medium by EDTA allowed efficient recovery of eggs and vermiform stages of R. reniformis. Extraction efficiency was quantified with Radopholus similis as a test organism. The efficiency of extracting R. similis from the gellan gum did not vary with the concentrations of EDTA tested.
Contemporary Cryptology: The Science of Information Integrity (1994)

The field of cryptography has experienced an unprecedented development in the past decade and the contributors to this book have been in the forefront of these developments. In an information-intensive society, it is essential to devise means to accomplish, with information alone, every function that it has been possible to achieve in the past with documents, personal control, and legal protocols (secrecy, signatures, witnessing, dating, certification of receipt and/or origination). This volume focuses on all these needs, covering all aspects of the science of information integrity, with an emphasis on the cryptographic elements of the subject. In addition to being an introductory guide and survey of all the latest developments, this book provides the engineer and scientist with algorithms, protocols, and applications. Of interest to computer scientists, communications engineers, data management specialists, cryptographers, mathematicians, security specialists, network engineers
Wind velocity profile reconstruction from intensity fluctuations of a plane wave propagating in a turbulent atmosphere (2007)

Reconstruction of a wind profile based on the statistics of plane-wave intensity fluctuations in a turbulent atmosphere is considered. The algorithm for wind profile retrieval from the spatiotemporal spectrum of plane-wave weak intensity fluctuations is described, and the results of end-to-end computer experiments on wind profiling based on the developed algorithm are presented. It is shown that the reconstructing algorithm allows retrieval of a wind profile from turbulent plane-wave intensity fluctuations with acceptable accuracy.
Crowdsourcing 3D cultural heritage: best practice for mass photogrammetry (2019)

Purpose The purpose of this paper is to present the rationale for democratising the digital reproduction of cultural heritage via “mass photogrammetry”, by providing approaches to digitise objects from cultural heritage collections housed in museums or private spaces using devices and photogrammetry techniques accessible to the public. The paper is intended as a democratised approach rather than as a “scientific approach” for the purpose that mass photogrammetry can be achieved at scale. Design/methodology/approach The methodology aims to convert the art of photogrammetry into a more mechanical approach by overcoming common difficulties faced within exhibition spaces. This approach is replicable and allows anyone possessing inexpensive equipment with basic knowledge of photogrammetry to achieve acceptable results. Findings The authors present the experience of acquiring over 300 3D models through photogrammetry from over 25 priority sites and museums in East Asia. The approach covers the entire process from capturing to editing, and importing 3D models into integrated development environments for displays such as interactive 3D, Virtual Reality and Augmented Reality. Practical implications The simplistic approach for democratised, mass photogrammetry has implications for stirring public interests in the digital preservation of heritage objects in countries where museums and cultural institutions have little access to digital teams, provided that Intellectual Property issues are cared for. The approach to mass photogrammetry also means that personal cultural heritage objects hidden within the homes of various societies and relics in circulation in the antiques market can be made accessible globally at scale. Originality/value This paper focuses on the complete practical nature of photogrammetry conducted within cultural institutions. The authors provide a means for the public to conduct good photogrammetry so that all cultural heritage objects can be digitally recorded and shared globally so as to promote the cross-cultural appreciation of material cultures from the past.
Firmware-only implementation of time-to-digital converter (TDC) in field-programmable gate array (FPGA) (2003)

A Time-to-Digital Converter (TDC) implemented in general purpose field-programmable gate array, (FPGA) for the Fermilab CKM experiment will be presented. The TDC uses a delay chain and register array structure to produce lower bits in addition to higher bits from a clock counter. Lacking the direct controls custom chips, the FPGA implementation of the delay chain and register array structure had to address two major problems: (1) The logic elements used for the delay chain and register array structure must be placed and routed by the FPGA compiler in a predictable manner, to assure uniformity of the TDC binning and short-term stability. (2) The delay variation due to temperature and power supply voltage must he compensated for to assure long-term stability. We used the chain structures in the existing FPGAs that the venders designed for general purpose such as carry algorithm or logic expansion to solve the first problem. To compensate for delay variations, we studied several digital compensation strategies that can be implemented in the same FPGA device. Some bench-top test results will also be presented in this document.
Inhibition of saccades elicits attentional suppression (2013)

Visuospatial attention has been shown to have a central role in planning and generation of saccades but what role, if any, it plays in inhibition of saccades remains unclear. In this study, we used an oculomotor delayed match- or nonmatch-to-sample task in which a cued location has to be encoded and memorized for one of two very different goals-to plan a saccade to it or to avoid making a saccade to it. We measured the spatial allocation of attention during the delay and found that while marking a location as a future saccade target resulted in an attentional benefit at that location, marking it as forbidden to saccades led to an attentional cost. Additionally, saccade trajectories were found to deviate away more from the "don't look" location than from a saccade-irrelevant distractor confirming greater inhibition of an actively forbidden location in oculomotor programming. Our finding that attention is suppressed at locations forbidden to saccades confirms and complements the claim of a selective and obligatory coupling between saccades and attention-saccades at the memorized location could neither be planned nor suppressed independent of a corresponding effect on attentional performance.
Focal Liver Lesion Detection and Characterization with Diffusion-weighted MR Imaging: Comparison with Standard Breath-hold T2-weighted Imaging (2008)

DW MR imaging was better than standard breath-hold T2-weighted imaging for FLL detection and was equal to breath-hold T2-weighted imaging for FLL characterization.
Testosterone and energetics in wild chimpanzees (<i>Pan troglodytes schweinfurthii</i>) (2005)

Ovarian function in female hominoids is sensitive to both energy flux and energy balance, resulting in a reduced probability of conception during periods when a successful reproductive outcome is less likely. However, the extent to which energetic factors constrain gonadal function in male hominoids is not clear. We examined the effects of both acute and chronic variation in energy availability on urinary testosterone (T) levels in adult male chimpanzees. Acute changes in energy availability, which were assayed by means of observational data on feeding behavior, did not result in decreased T production for 11 individuals at Kibale National Park, Uganda. Chronic energy shortages, on the other hand, may be associated with lower T levels in this population. Adult males in Kibale (n=11), who maintain suboptimal access to energy, exhibit significantly lower urinary T levels than males in captivity (n=11), who are more sedentary and better fed. These results suggest that data on hormonal function in captive chimpanzees should be interpreted with caution because individuals may produce T at levels well above those that are typical in the wild. They also suggest that short-term variations in T levels in male hominoids are more likely to be explained by social factors than by energetic ones.
Scope for Reducing Indigenous Imprisonment Rates, The (2001)

The over-representation of indigenous Australians in prison continues to be a serious problem, even a decade after the recommendations of the Royal Commission into Aboriginal Deaths in Custody were handed down. The gaps in our knowledge about indigenous persons in the criminal justice system, however, have made it difficult to gauge where efforts to reduce indigenous imprisonment might be best placed. This bulletin provides new information on the over-representation of indigenous persons in the NSW court system and on the offence profile and penalties imposed on indigenous and non-indigenous offenders. The findings indicate that the over-representation of indigenous persons stems initially from their higher rate of appearance at court, but is amplified at the point of sentencing, with indigenous offenders sentenced to imprisonment at almost twice the rate of non-indigenous persons. The violent nature of indigenous convictions and the greater likelihood of indigenous persons having prior convictions were found to contribute to their higher rate of imprisonment. These findings suggest that the greatest leverage for reducing indigenous imprisonment rates appears to lie in reducing the rate at which indigenous persons appear in court rather than in reducing the rate at which convicted offenders are sentenced to imprisonment.
Obtaining structural information from the atomic pair distribution function (2004)

Abstract The knowledge of the detailed atomic structure of modern materials is the key to understanding the their macroscopic properties. The atomic pair distribution function (PDF) reveals short-range and medium-range structural information. In this paper we present an overview of refinement and modelling techniques. In short, we will be trying to answer the question: What can I learn from my PDF?
[Sensitivity and specificity of the Heidelberg retinal tomograph for imaging nerve fiber bundle defects in glaucoma patients with localized visual field defects. Clinical study]. (1995)

In order to verify whether nerve fiber bundle defects can be detected by the confocal technique of the Heidelberg Retina Tomograph (HRT), we compared the localization of localized visual field defects with the localization of the expected corresponding nerve fiber bundle defect. We examined 105 patients: 49 with primary open-angle glaucoma (POAG), 26 with low-tension glaucoma (LTG) and 10 with ocular hypertension (OH), and as a control-group 20 healthy eyes. The glaucoma stage had been defined by examination of the central visual field with the Octopus Perimeter 201 program 31 or 32 and/or the Humphrey Perimeter GG program. In healthy eyes, eyes with OH and POAG stage I (n = 19), no nerve fiber bundle defect could be found. In stage II (n = 15) and stage III (n = 14) we found nerve fiber bundle defects in all patients with POAG and LTG (except for one patient with POAG stage III). In stage IV (n = 27) no localized nerve fiber bundle defects were detected in eyes with POAG, but in 4 of 7 patients with LTG, defects could be seen. In glaucoma stages II and III, nerve fiber bundle defects can be detected with the HRT. The control group shows, that the appearance of a nerve fiber bundle defect is no artifact caused by the HRT. However, examination of eyes with OH and POAG stage I also shows that this method is not sensitive enough to be useful for early diagnosis of glaucoma. Nevertheless, it may be possible to develop the confocal HRT method further as a nerve-fiber diagnostic method for glaucoma.