gebhart/patrepeval huggingface dataset:
Control of the ledge thickness in high-temperature metallurgical reactors using a virtual sensor (2012)

A non-intrusive inverse heat transfer procedure for predicting the time-varying thickness of the phase change ledge on the inside surface of the walls of a high-temperature metallurgical reactor is presented. A Kalman filter, based on a state-space representation of the reactor, is coupled with a recursive least-square estimator in order to estimate online the position of the phase front. The data are collected by a heat flux sensor located inside or outside of the reactor wall. The inverse method, used here as a virtual sensor, is coupled to a classic proportional–integral controller in order to control the ledge thickness by regulating the air cooling applied on the outside surface of the reactor wall. The virtual sensor and the control strategy are thoroughly tested for typical phase change conditions that prevail inside industrial facilities. Results show that a virtual sensor that relies on a heat flux sensor embedded inside the reactor wall provides more accurate and stable information, but at a price of a more complicated installation. In that case, it is shown that the discrepancy between the exact and the estimated ledge thicknesses remains smaller than 3% at all times, and that the control strategy ensures a null steady-state tracking error, a maximum tracking error less than 10%, no overshoot and no significant time lag.
PBGA for high power: extending the thermal envelope (2002)

ULSI devices continue to evolve in the direction of higher pincounts, powers and clock speeds. Current usage of the (cavity up) PBGA has been limited to I/Os of 150-360 and powers of 2-3 W. There is a need to extend the performance characteristics of the PBGA as a low cost packaging alternative for evolving devices. This study reports on the thermal performance of a 400 I/O PBGA design for powers of 7-10 W for PC/Workstation applications. Thermal performance is improved by lowering the resistances to heat flow via junction to board (R/sub jb/), junction to case (R/sub jc/) and case to ambient (R/sub ca/). The case to ambient resistance is lowered by using a heat sink attached to the package, evaluated at forced air flow of 1 m/s, typical for workstation environments. A PBGA package has been developed for a 12.7 mm die on a 29 mm, 2 metal layer substrate. The design utilizes thermal vias to lower the R/sub jb/. R/sub jc/ is lowered by decreasing the mold compound thickness. Design parameters for these features are derived and optimized through finite element simulations. Attaching a heatsink to the package is critical for extending the power dissipation from 2-3 W to the 7+ W range. The peripheral area around the PBGA makes it naturally suited for a demountable heatsink attach. An easy clip-on method of heatsink attach is developed as an alternative to the current time-consuming practice of epoxy bonding. Spring loaded clip attach prototypes are designed to minimize interfacial resistance to 0.75/spl deg/C/W when the heatsink is in dry contact with the mold compound.
Protective effect of quercetin on renal ischemia/reperfusion injury in rats (2003)

These results suggest that quercetin reduces renal oxidative injury and facilitates repair. Quercetin can have a role in a renoprotective therapeutic regimen.
Semiactive Control for Vibration Attenuation (1994)

With the advent of materials, such as electrorheological fluids, whose material prop erties can be altered rapidly by means of external stimuli, employing such materials as actuators for the controlled attenuation of undesirable vibrations is now possible. Such control schemes are dubbed semiactive in that they attenuate vibrations whether applied actively or passively. We in vestigate various such control schemes, allowing for both separate and joint control of the stiffness and damping characteristics of the material.
Low-cost microarray thin-film electrodes with ionic liquid gel-polymer electrolytes for miniaturised oxygen sensing (2016)

A robust, miniaturised electrochemical gas sensor for oxygen (O2) has been constructed using a commercially available Pt microarray thin-film electrode (MATFE) with a gellified electrolyte containing the room temperature ionic liquid (RTIL) 1-ethyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide ([C2mim][NTf2]) and poly(methyl methacrylate) (PMMA) in a 50 : 50 mass ratio. Diffusion coefficients and solubilities for oxygen in mixtures of PMMA/RTIL at different PMMA doping concentrations (0-50% mass) were derived from potential step chronoamperometry (PSCA) on a Pt microdisk electrode. The MATFE was then used with both the neat RTIL and 50% (by mass) PMMA/RTIL gel, to study the analytical behavior over a wide concentration range (0.1 to 100 vol% O2). Cyclic voltammetry (CV) and long-term chronoamperometry (LTCA) techniques were employed and it was determined that the gentler CV technique is better at higher O2 concentrations (above 60 vol%), but LTCA is more reliable and accurate at lower concentrations (especially below 0.5% O2). In particular, there was much less potential shifting (from the unstable Pt quasi-reference electrode) evident in the 50% PMMA/RTIL gel than in the neat RTIL, making this a much more suitable electrolyte for long-term continuous oxygen monitoring. The mass production and low-cost of the electrode array, along with the minimal amounts of RTIL/PMMA required, make this a viable sensing device for oxygen detection on a bulk scale in a wide range of environmental conditions.
Carcinoma of Penis: Improved Survival by Early Regional Lymphadenectomy Based on Histological Grade and Depth of Invasion of Primary Lesion (1995)

By classifying disease according to the depth of invasion and degree of differentiation of the primary lesions a high degree of accuracy could be obtained in predicting the likelihood of positive groin nodes. Removing groin nodes that are microscopically positive improves the survival rate over that of delayed lymphadenectomy.
Experimental Embolization in Kidneys: Tissue Concentration of Antibiotics (1979)

In 7 dogs renal arterial embolization was performed using the Seldinger technique and an inflatable Swan Ganz balloon catheter. Methyl methacrylate and butyl-2-cyanoacrylate were injected. 6 months later, the tissue concentration of Cefazolin was measured in the embolized and contralateral kidneys and in serum 2 h after a short infusion of 1 h Cefazolin. The concentrations in serum and homogenized kidney tissue were determined by means of the agar gel diffusion method. Angiography showed no vessels in the embolized kidneys. Histologically there was total atrophy of the tissue, especially of the tubular system. The mean tissue level of Cefazolin in the embolized kidney was 70% of serum. The tissue concentration was always above 10 micrograms/g. This concentration is high enough to inhibit nearly all strains of E. coli, Klebsiella, Salmonella, Shigella and a large part of Proteus mirabilis, whereas nearly all gram-positive bacteria are inhibited at a lower concentration. The value and necessity of antibiotic therapy in embolized kidney cancer is discussed.
Simultaneous detection of landmarks and key-frame in cardiac perfusion MRI using a joint spatial-temporal context model (2011)

Cardiac perfusion magnetic resonance imaging (MRI) has proven clinical significance in diagnosis of heart diseases. However, analysis of perfusion data is time-consuming, where automatic detection of anatomic landmarks and key-frames from perfusion MR sequences is helpful for anchoring structures and functional analysis of the heart, leading toward fully automated perfusion analysis. Learning-based object detection methods have demonstrated their capabilities to handle large variations of the object by exploring a local region, i.e., context. Conventional 2D approaches take into account spatial context only. Temporal signals in perfusion data present a strong cue for anchoring. We propose a joint context model to encode both spatial and temporal evidence. In addition, our spatial context is constructed not only based on the landmark of interest, but also the landmarks that are correlated in the neighboring anatomies. A discriminative model is learned through a probabilistic boosting tree. A marginal space learning strategy is applied to efficiently learn and search in a high dimensional parameter space. A fully automatic system is developed to simultaneously detect anatomic landmarks and key frames in both RV and LV from perfusion sequences. The proposed approach was evaluated on a database of 373 cardiac perfusion MRI sequences from 77 patients. Experimental results of a 4-fold cross validation show superior landmark detection accuracies of the proposed joint spatial-temporal approach to the 2D approach that is based on spatial context only. The key-frame identification results are promising.
Novel 13C-detected Experiments for Nucleic Acids (2007)

The bases of nucleic acids contain several quaternary carbon
atoms whose detection through the remote protons is difficult
or impossible, but that are suitable for the direct carbon
detection. Moreover, the network of coupled carbon spins in
13C-enriched compounds causes splitting of the signals in the
directly detected dimension. This is a disadvantage in general
spectroscopy but it can be used as an easy way of measuring
carbon-carbon couplings.
Enrichment and immobilization of macromolecular analytes on a porous membrane utilizing permeation drag (2018)

Enrichment and immobilization of analytes by chemical bonding or physical adsorption is typically the first step in many commonly used analytical techniques. In this paper, we discuss a permeation drag based technique as an alternative approach for carrying out location-specific immobilization of macromolecular analytes. Fluorescein isothiocyanate (FITC) labeled macromolecules and their complexes were enriched near the surface of ultrafiltration membranes and detected by direct visual observation and fluorescence imaging. The level of macromolecule enrichment at the immobilization sites could be controlled by manipulating the filtration rate and thereby the magnitude of permeation drag. Higher enrichment as indicated by higher fluorescence intensity was observed at higher filtration rates. Also, larger macromolecules were more easily enriched. The feasibility of using this technique for detecting immunocomplexes was demonstrated by carrying out experiments with FITC labeled bovine serum albumin (FITC-BSA) and its corresponding antibody. This permeation drag based enrichment technique could potentially be developed further to suit a range of analytical applications involving more sophisticated detection methods.
Self-stacked Co3O4 nanosheets for high-performance lithium ion batteries (2011)

Self-stacked Co(3)O(4) nanosheets separated by carbon layers were synthesized via a facile method. They exhibit excellent electrochemical performance that results from superior electronic conductivity endowed by carbon, a reduced Li(+) diffusion length within the building blocks and a large electrode/electrolyte contact area due to the interspaces between the blocks.
Explosive-driven double-blast exposure: molecular, histopathological, and behavioral consequences (2020)

Traumatic brain injury generated by blast may induce long-term neurological and psychiatric sequelae. We aimed to identify molecular, histopathological, and behavioral changes in rats 2 weeks after explosive-driven double-blast exposure. Rats received two 30-psi (~ 207-kPa) blasts 24 h apart or were handled identically without blast. All rats were behaviorally assessed over 2 weeks. At Day 15, rats were euthanized, and brains removed. Brains were dissected into frontal cortex, hippocampus, cerebellum, and brainstem. Western blotting was performed to measure levels of total-Tau, phosphorylated-Tau (pTau), amyloid precursor protein (APP), GFAP, Iba1, αII-spectrin, and spectrin breakdown products (SBDP). Kinases and phosphatases, correlated with tau phosphorylation were also measured. Immunohistochemistry for pTau, APP, GFAP, and Iba1 was performed. pTau protein level was greater in the hippocampus, cerebellum, and brainstem and APP protein level was greater in cerebellum of blast vs control rats (p < 0.05). GFAP, Iba1, αII-spectrin, and SBDP remained unchanged. No immunohistochemical or neurobehavioral changes were observed. The dissociation between increased pTau and APP in different regions in the absence of neurobehavioral changes 2 weeks after double blast exposure is a relevant finding, consistent with human data showing that battlefield blasts might be associated with molecular changes before signs of neurological and psychiatric disorders manifest.
Histologic Evaluation of Melanomas (2005)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA Dermatology HomeNew OnlineCurrent IssueFor Authors Podcast Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA Dermatology journal
The Effect of Arginine or Glycine Supplementation on Gastrointestinal Function, Muscle Injury, Serum Amino Acid Concentrations and Performance During a Marathon Run (1999)

Gastrointestinal bleeding and increased intestinal permeability have been observed in marathon runners. We sought to determine if L-arginine would be useful for prevention of these complications. Twenty-three runners were randomized to receive L-arginine (A) or glycine (placebo) (G), 10 grams 3 times daily for 14 days prior to the 1997 Houston-Methodist Marathon. Serum, stool hemoccults and lactulose : mannitol permeabilities were obtained at baseline, immediately after completion of the marathon and approximately 48 hours later. Runners rated their symptoms of nausea and vomiting, belching and indigestion, abdominal pain and bloating, diarrhea, and extremity pain on a 1-5 scale of increasing severity. The L:M was unchanged in either group during the three collections. (Occult bleeding occurred in 8 % / 20 % in A and G groups, respectively, p = NS) immediately post-marathon. No runners had occult bleeding 48 hours post-race. Gastrointestinal symptom scores were minimal to nonexistent. Extremity pain scores were similar for groups A and G (2.1±1.4 and 2.8±1.6, respectively, (p = NS). Fluid intake was similar between both groups (187 5±1547 vs. 1506±970 ml, p = NS). Serum amylase was normal at baseline and remained virtually unchanged. Serum lipase was normal at baseline and immediately post-race in both groups, but increased at 48 hours post-race (82.2±34.3 to 121.5±53.3 mg/dl [A], p = 0.02 and 114.3±55.7 to 181.9±162.2 mg/dl [G], p = 0.09). CPK increased significantly and) similarly in both groups immediately post-race, and even more dramatically 48 hours post-race (130.3±130.8 to 738.8±902.9, p = 0.007 to 1966.5±3.166.0 mg/dl [A] and 140.9±77.9 to 863.0±772.3, p = 0.003 to 5619±10636.8 mg/dl [G]). Modest post-race decreases were seen in most serum amino acids in both groups. Finish times were longer than predicted (23±21 and 9±7 min for A and G groups, respectively, p = 0.049). Our study failed to show a clear benefit of arginine supplementation for the prevention of intestinal ischemia/reperfusion injury associated with endurance running, but either a detrimental affect on performance with arginine, or enhanced performance with glycine. Skeletal muscle injury was unaffected by arginine or glycine supplementation. The delayed increase in serum lipase suggests mild pancreatic injury, affected by either arginine or glycine supplementation.
Miscellanea no. 4 (1961)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTMiscellanea no. 4Karol J. Mysels Cite this: J. Chem. Educ. 1961, 38, 12, 627Publication Date (Print):December 1, 1961Publication History Received3 August 2009Published online1 December 1961Published inissue 1 December 1961https://doi.org/10.1021/ed038p627RIGHTS & PERMISSIONSArticle Views26Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (962 KB) Get e-Alertsclose Get e-Alerts
Nalidixic Acid-Resistant Auxotrophs of <i>Escherichia coli</i> (1970)

purB and ctr mutants of Escherichia coli are resistant to low levels of nalidixic acid.
Phosphorylation of Sox2 Cooperates in Reprogramming to Pluripotent Stem Cells (2010)

Somatic cells can be reprogrammed into induced pluripotent stem cells (iPSCs) by transduction of reprogramming factors, including Oct4, Sox2, Klf4, and c-Myc. A coordinated network of these factors was suggested to confer a pluripotency of iPSCs. Together with Oct4, Sox2 plays a major role as a master regulator in ESCs. However, the underlying mechanisms by which Sox2 contributes to self-renewal or reprogramming processes remain to be determined. Here, we provide new evidence for a phosphorylation-based regulation of Sox2 activity. Akt directly interacts with Sox2 and promotes its stabilization through phosphorylation at Thr118, which enhances the transcriptional activity of Sox2 in ESCs. Moreover, phosphorylation of Sox2 cooperates in the reprogramming of mouse embryonic fibroblasts by enabling more efficient induction of iPSCs. Overall, our studies provide new insights into the regulatory mechanism of Sox2 in ESCs and also provide a direct link between phosphorylation events and somatic cell reprogramming.
A fluid analysis of utility-based wireless scheduling policies (2004)

We consider packet scheduling for the downlink in a wireless network, where each packet's service preferences are captured by a utility function that depends on the packet's delay. The goal is to schedule packet transmissions to maximize the total utility. We examine a simple gradient-based scheduling algorithm, the UR-rule, which is a type of generalized c/spl mu/-rule (Gc/spl mu/) that takes into account both a user's channel condition and derived utility. We study the performance of this scheduling rule for a draining problem. We formulate a "large system" fluid model for this draining problem where the number of packets increases while the packet-size decreases to zero, and give a complete characterization of the behavior of the UR scheduling rule in this limiting regime. We then give an optimal control formulation for finding the optimal scheduling policy for the fluid draining model. Using Pontryagin's minimum principle, we show that, when the user rates are chosen from a TDM-type of capacity region, the UR rule is in fact optimal in many cases. Finally, we consider non-TDM capacity regions and show that here the UR rule is optimal only in special cases.
THE CONVERGENCE OF THE ALGORITHM FOR COMPOUND DISTANCE FEATURE EXTRACTION AND THE GENERAL REPRESENTATION OF OPTIMAL SUBSPACE (1993)

In the paper,we give an iff condition of optimal compound distanceJ and derive the general representation of optimal subspace.Furthermore weexplain how to gaurautee the convergence of the algorithm.These results willhave instructive effects on the utilization of the algorithm and be very helpful inthe further research of compound distance teature extraction.
A Fuzzy Regression Approach to Acquisition of Linguistic Rules (2008)

This chapter contains sections titled: Introduction Linguistic Variables and Vocabulary Matching Determination of Fuzzy Regression Model An Illustrative Example Concluding Remarks References
Mechanism of ultra-fine microstructure formation during ART-annealing of a Medium-Mn steel (2015)

International audience
Recording lightspace so shadows and highlights vary with varying viewing illumination (1995)

Methods are proposed to record the way in which objects respond to varying illumination—to capture and reproduce varying shadows and highlights and thus give the illusion that absent objects are present behind a “window” into which people may shine arbitrary lights of their choice. When the recording is viewed under two separate point sources, one sees a reproduction of the original scene with double shadows. When it is viewed outdoors, on an overcast day, one sees a reproduction of soft or almost nonexistent shadows, whereas the reproduction of the objects themselves remains sharply defined, regardless of the viewing illumination.
Ingegneria dei tessuti cardiaci (2012)

L’ingegneria tessutale cardiaca e una promessa per il futuro, e un processo innovativo per la cura di problemi cardiaci che possono essere congeniti, post-traumatici o verificarsi nel corso della vita di un essere umano. In questa trattazione varra in particolare analizzato anatomicamente e fisiologicamente il comportamento dell’organo cardiaco e delle cellule che principalmente lo compongono. Verranno analizzati i principali biomateriali impiegati in questo contesto facendo una distinzione tra naturali: collagene, fibrina, acido ialuronico, alginati, chitosano; e sintetici: PGA, PLA, PLGA, PTFE, PEG, PCL. Saranno poi descritti i vari approcci e le diverse strategie di formazione di neotessuto partendo dalle tipologie di scaffolds utilizzate e proseguendo con la scelta delle cellule da impiantare, fondamentalmente cellule staminali. Verra poi in conclusione descritta una particolare tipologia di patch cardiaca realizzata con nanofilamenti in oro su scaffold in alginato
Lagegeberlose Positionsregelung eines permanenterregten Synchronlinearmotors (2014)

Zusammenfassung Der Beitrag beschreibt eine Zwei-Freiheitsgrade-Positionsregelung für einen permanenterregten Synchronlinearmotor ohne Lagegeber. Zur Vermeidung von Schätzfehlern werden die differentiellen Kreuzkoppelinduktivitäten mit Hilfe einer flachheitsbasierten Vorsteuerung kompensiert. Die Reglerstellsignale werden für die Lage- und Geschwindigkeitsschätzung verwendet.