gebhart/patrepeval huggingface dataset:
ChemInform Abstract: XPS Investigations of Lanthanum in Faujasite‐Type Zeolites. (1993)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Bubble raft-an optical phantom for analyzing artifacts in OCT imaging of lung (2015)

Accurate measurement of alveolar volume by lung imaging is crucial to study and understand respiratory mechanics. Optical Coherence Tomography (OCT), which generates cross-sectional microscopic image of tissue structure in real time based on near-infrared interferometry, can image several layers of distal alveoli in intact, ex vivo lung tissue. However, optical effects associated with heterogeneity of lung tissue results in incorrect alveoli shape imaging and inaccurate assessment of lung volume. Due to the irregular cellular shape of lung tissue and the lack of ground truth, these errors are difficult to analyze, as well as remove. To address this, the Bragg-Nye bubble raft, a two-dimensional crystalline arrangement of elements similar in geometry to alveoli has been adapted as an inflated lung phantom to study and analyze these errors.
Elevation of B cell-activating factor belonging to the tumour necrosis family family (BAFF) in haemophilia A patients with inhibitor (2009)

Elevation of B cell-activating factor belonging to the tumour necrosis family family (BAFF) in haemophilia A patients with inhibitor -
Electrical Resistivity of Nickel-Palladium Alloys (1957)

The concentration dependence of the residual resistivity of Ni–Pd alloys might be expected to obey a simple Nordheim law since the number of holes in the d band and the number of electrons in the s band are approximately independent of composition. Measurements have indicated, however, that the maximum resistivity occurs at 70 atomic percent Pd instead of 50%. This behavior can be explained by the spin dependence of electron scattering processes associated with the fact that the alloys with greater than 3% Ni are ferromagnetic. Quantitative fit of the data is possible if it is assumed that the density of states at the Fermi energy in the d band is approximately proportional to the number of holes, rather than to the cube root of this number. Data on the resistivity and paramagnetic susceptibility of Ag–Pd alloys support this hypothesis. The relative strength of s-d scattering to s-s scattering must be assumed to be about 5:1.
Microscopic Investigation into the Irradiation Behavior of U<sub>3</sub>O<sub>8</sub>-Al Dispersion Fuel (1986)

The recent emphasis on profileration-resistant fuels for research and test reactors has resulted in additional investigations of well-established fuels, such as U3O8-Al dispersions, to determine their behavior at the higher fuel densities required for the lower uranium enrichment. Microstructural investigation of these irradiated fuels with modern techniques has provided insight into the fission gas behavior and its relationship to the U3O8-Al interaction during irradiation. These observations explain the observed limitations on fuel loading and safe levels of fission density achievable with these fuels.
Studies of Forced-Convection Heat Transfer Augmentation in Large Containment Enclosures (2001)

Heat transfer enhancement due to jet mixing inside a cylindrical enclosure is discussed. This work addresses conservative heat transfer assumptions regarding mixing and condensation that have typically been incorporated into passive containment design analyses. This research presents the possibility for increasing decay heat removal of passive containment systems under combined natural and forced convection. Eliminating these conservative assumptions could result in a changed containment design and reduce the construction cost. It is found that the ratio of forced- and free-convection Nusselt numbers can be predicted as a function of the Archimedes number and a correlated factor accounting for jet orientation and enclosure geometry.
Reduced Levels of Neutralizing Antibodies to Kaposi Sarcoma–Associated Herpesvirus in Persons with a History of Kaposi Sarcoma (2004)

Kaposi sarcoma-associated herpesvirus (KSHV) has been identified as the etiologic agent of Kaposi sarcoma (KS). Although KSHV is required for the development of KS, immune dysfunction is a common and important cofactor in the development of KS, as illustrated by the presence of KS in association with HIV infection or immunosuppressive-drug treatment after transplantation. Because neutralizing antibodies (NAb) constitute an important component of an antiviral immune response, we examined the functionality of the humoral immune response associated with KS, by measuring KSHV NAb titers in 3 groups of subjects. Group 1 included subjects who were KSHV positive, KS positive, and human immunodeficiency virus (HIV) positive; group 2 included subjects who were KSHV positive, KS negative, and HIV positive; and group 3 included subjects who were KSHV positive, KS negative, and HIV negative. NAb titers were significantly lower among subjects with KS, compared with subjects who were infected with KSHV but who did not have clinical evidence of KS, in a multivariate model adjusted for HIV infection and CD4 T cell count. The data from the present study suggest that NAb may play a role in the control of KSHV infection and the prevention of progression of KSHV infection to KS.
Hepatitis B virus infection initiates with a large surface protein–dependent binding to heparan sulfate proteoglycans (2007)

HBV infection requires the initial attachment to the carbohydrate side chains of hepatocyte-associated heparan sulfate proteoglycans as attachment receptors. This interaction initializes the multistep entry process of HBV and cannot be bypassed by alternative routes.
ChemInform Abstract: ALKYLIERUNG VON INDOLEN DURCH HALOGENMETHYLPHENOLE 2. MITT. UMLAGERUNG UNTER BETEILIGUNG DES INDOLKERNS (1973)

Abstract Das Dibrompropylphenol (I) und das hieraus durch Dehydrobromierung mit Na‐acetat erhaltene Methylenchinon (III) reagieren mit Indol (II) bei konstantem pH 3 zu einem Gemisch der Verbindungen (IV) (Hauptprodukt), (V und (VI) [Massenspektren von (III) und (V)].
Modified ’’Harvard’’ dry dust disperser (1975)

A modified dry dust disperser has been used to produce test aerosols from very fine powders which show a tendency to agglomerate in feeders and dispersion equipment.
Total Arterial Revascularization with Bilateral Internal Thoracic Artery: A long-term, Propensity Score-matched Comparison of Composite Y - BITA - Grafts to BITA - in situ Grafting (2016)

Background: Coronary artery bypass graft surgery (CABG) utilizing bilateral internal thoracic arteries (BITA) for total arterial revascularization (TAR) can be performed by constructing a composite Y - BITA - graft or by using the BITAs as in situ grafts. Although previously reported on this topic, validation of the results in a current surgical experience is needed. We compared the early and long-term clinical outcomes in patients who received BITA as Y with BITA in situ grafts.
The human homologue of the yeast polyubiquitination factor Ufd2p is cleaved by caspase 6 and granzyme B during apoptosis (2002)

In the present study, we demonstrate that a human homologue of Ufd2p (a yeast protein that catalyses the formation of long polyubiquitin chains, and is implicated in responses to environmental stress), UFD2 (ubiquitin fusion degradation protein-2), is cleaved during apoptosis induced by multiple stimuli, including UVB irradiation, Fas ligation, staurosporine treatment and cytotoxic lymphocyte granule-induced death. Caspase 6 and granzyme B efficiently cleave UFD2 [k(cat)/K(m)=(4-5) x 10(4) M(-1) x s(-1)] at Asp(123), whereas caspases 3 and 7 cleave UFD2 approx. 10-fold less efficiently immediately upstream at Asp(109). Thus UFD2 is added to the growing list of proteins with closely spaced caspase and granzyme B cleavage sites, suggesting the presence of a previously unrecognized, conserved motif. Both cleavage sites are contained and conserved within a novel 300-amino-acid N-terminal domain present in apparent UFD2 orthologues in mice and zebrafish, but absent in all UFD2 family members in lower eukaryotes. Full-length recombinant UFD2 exhibited ubiquitin-protein ligase ('E3')-like ubiquitination activity in vitro, but this activity was abolished in recombinant UFD2 truncated at the granzyme B/caspase 6 cleavage site. Cleavage of UFD2 by caspases or granzyme B within this putative regulatory N-terminal domain might have important functional consequences within the apoptotic cascade.
Thietanes. Syntheses, configurations, and conformations of 2,4-diphenylthietanes and their oxides (1970)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThietanes. Syntheses, configurations, and conformations of 2,4-diphenylthietanes and their oxidesRaymond M. Dodson, E. H. Jancis, and G. KloseCite this: J. Org. Chem. 1970, 35, 8, 2520–2525Publication Date (Print):August 1, 1970Publication History Published online1 May 2002Published inissue 1 August 1970https://pubs.acs.org/doi/10.1021/jo00833a011https://doi.org/10.1021/jo00833a011research-articleACS PublicationsRequest reuse permissionsArticle Views94Altmetric-Citations33LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Life support breathing system for: “SubPack” — rebreather system (2009)

In response to requirements by OceanWorks International, a Rescue Rebreather, called "SubPack" was designed and built by O <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> Dive Technologies of TX, under contract for the REMORA rescue submarine for the Australian Navy. Operational requirements sometimes required entering or transiting an area, which may be contaminated with toxic industrial chemicals, fire by-products or chemical or biological agents. Depending on the situation, it may not be acceptable or operationally suitable for the personnel to use 'open loop' or negative pressure filtered respirators due to the nature of the contaminant or even its physical state (e.g. super heated air). In these situations a closed circuit breathing system is required. SubPack Rebreather, is capable of 180 minutes of life support, is ergonomically small, lightweight (weighing less then 20 lbs.), rapidly donnable, low cost, and interface with existing full-face masks with standard NATO interfaces. Additionally, it is to be easy to maintain, and have a short training period for first responders. Besides these fundamental requirements, OceanWorks provided valuable meetings that their various needs were also incorporated into the design. SubPack is a closed circuit rebreather unit and is expected to go on for NIOSH testing and approval. Its many design features allow it to be adapted for all capabilities including meeting NFPA requirements of passive alarm and heads up display. A second unit was designed and built to meet Long duration, high exertion, and environment. Originally, designed for search and rescue for miners, the Miners Rescue ReBreather System has a low breathing resistance, no aftermarket requirements for gas cooling and has six hour duration. Further adaptations will include and other rigorous environments and applications. This device will be of commercial interest to DOD/SOCOM, FBI, and USSS, other federal, state and local Law Enforcement Agencies, fire fighters, urban and rural rescue teams and industrial First Responders. The SubPack unit, and all components herein are prototype proprietary O <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> Dive Technologies Inc.
Effect of combination inhibition of vascular endothelial growth factor (VEGF) and epidermal growth factor receptor (EGF-R) on ovarian cancer cell lines (2006)

13112 Background: Bevacizumab, a VEGF inhibitor, and cetuximab, an EGF-R inhibitor, have shown promising results in the treatment of solid tumors. The combination of these two antibodies and combinations with platinum chemotherapy is of interest for the treatment of ovarian cancer. Our objective is evaluate the mechanism of action and to determine the direct effect on tumor proliferation, the role of antibody dependent cell cytotoxicity (ADCC) with immune effector cells and the outcome in nude mouse xenografts with antibody treatment combinations. Methods: Five ovarian cancer cell lines were studied; SKOV3, SKOV8, OVCAR3, A2780, and CaOV3. VEGF secretion levels were determined for each cell line by standard ELISA. EGF-R, VEGF-R and VEGF surface expression was determined by flow cytometry. Cytotoxicity alamar blue 96-well plate assays were performed and cells were plated and exposed to bevacizumab or cetuximab alone, in combination and with cisplatin. Standard 51 chromium release assays were performed to determine if bevacizumab and cetuximab have a role in ADCC when combined with peripheral blood mononuclear cells (PBMC). Results: All ovarian cancer cell lines secreted VEGF ranging from 210 to 1,849 pg/ml. Flow cytometry studies demonstrated varying degrees of expression of VEGF-R and minimal surface expression of VEGF ligand. EGF-R was present on all cell lines. Five day alamar blue cytotoxicity assays using varying concentrations of single agent bevacizumab (0.1–10 μM) or single agent cetuximab (0.01–1.0 μM) had minimal to no cytotoxic effect on ovarian cancer cell lines. The IC 50 for cisplatin in these cell lines was obtained and ranged from 1–5 μM and was not altered by the addition of antibodies. In 51 chromium release assays, the combination of bevacizumab and cetuximab caused a trend toward increased SKOV3 cell lysis by PBMC. Conclusion: Bevacizumab or cetuximab alone or in combination with each other in vitro had minimal direct cytotoxic effect. ADCC may be a mechanism of cell lysis when these antibodies are combined with effector cells (PBMC) and further studies are underway. In vivo studies with nude mouse SKOV3 xenografts are being performed to evaluate the effect on combination antibody therapy on established tumors. No significant financial relationships to disclose.
Unidirectional joint communications in wrist arthrography: an evaluation of 250 cases. (1991)

Although arthrographically demonstrable communications between various compartments of the wrist occur in older persons without symptoms, similar communications in younger persons may indicate clinically significant posttraumatic ligament tears and other pathologic processes. However, detection of communications varies depending on the arthrographic technique used. It has been claimed that if triple-compartment arthrography is not used in all patients, clinically significant unidirectional ligament tears may be overlooked. We determined the frequency and distribution of unidirectional intercompartmental communications, using a modification of techniques described in the literature. Separate injections of contrast material were made in sequence into the midcarpal, distal radioulnar, and radiocarpal joints of 250 consecutive patients. We found 38 unidirectional communications (17 lunotriquetral, nine scapholunate, three radial capsular, one ulnar capsular, six combined sites, and two indeterminate sites) between the midcarpal and radiocarpal joints. Nine unidirectional communications between the radiocarpal and distal radioulnar joints were found. Comparison of these results with the frequency and direction of unidirectional communications reported by others suggests that demonstration of communications depends on specific technical factors, such as which joint is injected first, the amount of contrast material used, and the delay between injections. This dependence on technical factors raises questions about the value of routine three-compartment wrist arthrography.
Advanced DFS: a dispersed fringe sensing algorithm insensitive to small calibration errors (2010)

Dispersed Fringe Sensing (DFS) is an elegant method of coarse phasing segmented mirrors. DFS performance accuracy is dependent upon careful calibration of the system as well as other factors such as internal optical alignment, system wavefront errors, and detector quality. Novel improvements to the algorithm have led to substantial enhancements in DFS performance. In this paper, we present Advanced DFS, an advancement of the DFS algorithm, which allows the overall method to be less sensitive to calibration errors. This is achieved by correcting for calibration errors, which appear in the fitting equations as a signal phase term. This paper will outline a brief analytical explanation of the improvements, results of advanced DFS processed simulations and experimental advanced DFS results.
Asymptotic analysis of stagnating turbulent flows (1991)

The k-e theory is applied to describe turbulence stagnating against a wall in the limit of large Reynolds. Such turbulence involves three regions: a viscous sublayer, a shear layer, and the external stream approching the wall.
Control of underwater vehicle/manipulator with composite dynamics (1998)

This paper is devoted to the problem of control design of an underwater vehicle/manipulator (UVM) system composed of a free navigating platform equipped with a robot manipulator. This composite system is driven by actuators and sensors of different nature having substantially different bandwidth characteristics. Such a difference allows for a setup which can naturally treated by standard singular perturbation theory. The major finding here is that the computed torque control law can be substantially simplified while preserving the closed-loop stability, in the sense of perturbation theory.
Synthesis and characterization of ultra-small superparamagnetic iron oxide nanoparticles thinly coated with silica (2008)

Ultra-small superparamagnetic iron oxide nanoparticles (SPIOs) were synthesized by co-precipitation of iron chloride salts with ammonia and then encapsulated with thin (~2nm) layers of silica. The particles have been characterized for size, diffraction pattern, surface charge, and magnetic properties. This rapid and economical synthesis has a number of industrial applications; however, the silica-coated particles have been optimized for use in medical applications as MR contrast agents, biosensors, DNA capturing, bioseparation and enzyme immobilization.
<sup>18</sup>F‐fluorodeoxyglucose positron emission tomography/computed tomography in the evaluation of early response in a primary hepatic lymphoma (2006)

We present a case of a 58-year-old man with a diagnosis of primary hepatic lymphoma, classified as diffuse large B-cell lymphoma. The patient also suffered from hepatitis C virus (HCV)-related chronic hepatitis. He underwent a total body 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) scan, which revealed two hypodense CT lesions in the left lobe and in the fifth segment of the liver, both showing intense 18F-FDG uptake (top figures); no other pathological uptake was observed. Thereafter, the patient underwent chemotherapy with six courses of R-CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine and prednisone). After two courses of therapy the 18F-FDG PET/CT scan was repeated; while persistence of liver disease was suggested by CT, no 18F-FDG uptake was evident (bottom figures). At the end of the treatment one hypodense lesion was still present on the CT scan, while the PET scan remained negative. After 25 months the patient is still alive and in complete remission. Primary hepatic non-Hodgkin lymphoma (NHL) is very rare, representing <0·016% of all NHL. It has often been associated with HCV infection. In the case presented here,18F-FDG PET/CT scanning was very useful in evaluating the early response to treatment and in confirming the absence of active disease at the end of treatment.
VLSI-based image bar for laser beam recording (1984)

There are many image bar technologies which make use of a full width light modulator which projects one-to-one onto the photoconductor. An alternative to these full width image bars makes use of a micro image bar, in which all of the drive electronics are integrated on a single monolithic VLSI circuit. The TIR linear spatial light modulator is such a device which is built using an integrated circuit in conjunction with an electro-optic crystal to achieve light modulation.
Treatment with argon plasma coagulation for hemorrhagic gastric angiodysplasia in chronic renal failure patients undergoing maintenance dialysis. (2002)

胃angiodysplasiaは健常者に比して維持透析患者に多くみられ, 時に消化管出血の要因となる. また, gastric antral vascular ectasia (GAVE) は, 胃幽門部の粘膜下毛細血管あ拡張と線維筋性過形成を特徴とした比較的まれな疾患で1984年にJabbariらにより報告された.われわれはGAVEを含む3例の胃angiodysplasiaをアルゴンプラズマ凝固法 (APC) で治療を行った. 症例1: 60歳, 女性. 7年間CAPD療法を継続. 平成11年3月, 心窩部痛と著明な貧血から上部消化管内視鏡検査を施行, 幽門を中心に典型的なwatermelon stomachの像を認めた. 症例2: 52歳, 男性. 平成7年にCAPD療法へ導入. 平成11年2月より繰り返すタール便と著明な貧血 (Hgb 3.7g/dL, Hct 11.2%) のため入院. 内視鏡にて胃幽門部に散在する毛細血管拡張像を認め, 同部位よりoozingが確認された. 症例3: 51歳, 男性. 昭和61年に慢性腎不全のため, HDへ導入. 平成10年3月に肝硬変に伴う門脈圧亢進症に対しtransjugular intrahepatic portosystemic shunt術を施行. 平成11年7月, 強度の貧血と黒色便のため緊急入院. 内視鏡検査で幽門領域にoozingを伴うびまん性の毛細血管拡張像を認め, diffuse antral vascular ectasiaと診断した. これら3症例にAPCを行い, 症例1, 2に関してはその後6か月, 貧血の進行は認めず, 症例3も輸血の頻度は減少し大きな効果があった. 透析患者において急速に進行する貧血を伴う消化管出血の原因として重要な疾患の一つである胃angiodysplasiaに対して, APCは合併症も少なく, 安全に行える有効な治療法であると考えられた.
Prevailingly Cationic Agmatine-Based Amphoteric Polyamidoamine as a Nontoxic, Nonhemolytic, and “Stealthlike” DNA Complexing Agent and Transfection Promoter (2007)

AGMA1, a prevailingly cationic amphoteric polyamidoamine obtained by polyaddition of (4-aminobutyl)guanidine (agmatine) to 2,2-bis(acrylamido)acetic acid, was studied as a potential DNA carrier and transfection promoter. Fluorescein-labeled AGMA1 was prepared by conjugation with fluorescein isothiocyanate and its cell uptake, blood permanence, and body distribution studied. In spite of its cationic character, AGMA1 is neither toxic nor hemolytic in the pH range 4.0−7.4, circulates for a long time in the blood without preferentially localizing in the liver, easily enters HT-29 cells, gives stable complexes with DNA, and is endowed with good transfection efficiency, suggesting the ability to transport in the cytoplasm a DNA payload without any measurable membranolytic activity. If compared with other transfection promoters, including polyamidoamines of different structures, AGMA1 is apparently endowed with a unique combination of desirable requirements for a nonviral DNA polymer carrier and warrants potential as a transfection agent in vivo.