gebhart/patrepeval huggingface dataset:
Original Functional Rehabilitation Programme Based on Healing Physiology After Reconstruction of Articular Cartilage in Knee Joint (2014)

Objectives: The evaluation of the quality of articular cartilage remodelling by means of arthroscopy findings and MRI imaging in a patient, who completed the original rehabilitation program. Methods: The rehabilitation program was conducted according to the Carolina Medical Center rehabilitation protocol. The patient was a 46 years old woman with fourth-degree cartilage damage (Outerbridge classification) located on the right medial femoral condyle of the following size: 1.5x2cm and 1x1.5cm. An arthroscopic micro-fracture repair of the cartilage was performed on the medial femoral condyle of the right knee. After the surgery the original rehabilitation program has been divided into 4 stages based on biological aspects of the physiology of cartilage tissue healing and biomechanics of the knee joint. 18 months after the reconstruction and a complete rehabilitation program, the patient underwent another right knee arthroscopy. During the surgery cartilage was been reevaluated in vivo. A pre-operative MRI was made, as well as a post-operative one after the second arthroscopy. The aim of the MRI examination was to objectify the treatment’s results. Results: The applied surgical treatment and following rehabilitation resulted in the remodelling of the cartilage-like tissue, which was observed in, both, the arthroscopy and the MRI imaging. The MRI evaluation of the quality of the cartilage tissue 18 months after the reconstruction gave very good results according to the MOCART scale (magnetic resonance observation of cartilage repair tissue). Conclusion: The positive results of the cartilage remodelling process recorded after the application of the original rehabilitation programme encourages to continue the study on a larger group of patients.
Postoperative imaging of the multichannel cochlear implant. (1995)

Plain radiographs of the temporal bone are sufficient for the postoperative treatment of the majority of postimplant patients. CT should be performed when plain radiographs cannot adequately show the location of the electrode array or if postoperative infection is suspected.
Short-Term Planning of Batch Plants in Process Industries (2001)

The paper deals with short-term planning problems in process industries where final products are obtained by several successive chemical or physical transformations of raw materials using scarce multi-purpose equipment. In batch production mode, the total requirements for intermediate and final products are partitioned into batches. The production start of a batch at a given level requires the availability of all input products. We consider the problem of scheduling the production of given primary requirements for final products such that the makespan is minimized, where the batch sizes can be chosen within prescribed intervals. Further constraints arise from limited production and storage capacities as well as sequence-dependent cleaning times for processing units. We propose a new solution approach which is based on the decomposition of the short-term planning problem into computing appropriate batch sizes (batching) and the subsequent scheduling of batches on processing units (batch scheduling). The former problem is modelled and solved as a nonlinear mixed integer program, whereas the latter problem is addressed using models and methods of resource-constrained project scheduling. The solution procedure proposed (approximately) solves problems of industrial size within a reasonable amount of computing time.
Surface functionalisation of diatoms with dopamine modified iron-oxide nanoparticles: toward magnetically guided drug microcarriers with biologically derived morphologies (2010)

Diatom silica microcapsules prepared by purification of diatomaceous earth (DE) were functionalised by dopamine modified iron-oxide nanoparticles, in order to introduce diatoms with magnetic properties. The application of magnetised diatoms as magnetically guided drug delivery microcarriers has been demonstrated.
Cardiac Arrhythmias Induced by Minimal Doses of Epinephrine in Cyclopropane-Anesthetized Dogs (1960)

Very small doses (0.1 to 2.0 µg./Kg.) of epinephrine injected in 1 minute into dogs anesthetized with 20 per cent cyclopropane cause a coupled rhythm which is usually bigeminal and characterized by an exceptionally constant interval between the coupled beats. Phenyiephvine also causes this arrhythmia, methoxamine does so rarely, but isoproterenol does not. An elevation in systolic pressure and possibly a tachycardia are required for the appearance of bigeminy. However, this arrhythmia can be elicited consistently by these factors only in the presence of a sympathomimetic amine with cardiac stimulant actions. A focus of automaticity has been ruled out in the genesis of the abnormal ventricular beat by demonstrating the constancy of the coupling interval despite sudden changes in the atrial rate. Dichloroisoproterenol appears to attenuate the induction of bigeminy by epinephrine to a considerably lesser extent than the major arrhythmias expected on injection of large doses of this sympathomimetic.
40 GHz adiabatic compression of a modulator based dual frequency beat signal using Raman amplification in dispersion decreasing fiber (2004)

We demonstrate the use of distributed Raman amplification (DRA) in a dispersion decreasing fiber (DDF) for the efficiency enhancement of adiabatic soliton compression of a dual frequency beat signal. We compress a 40 GHz beat signal generated from a LiNbO3 modulator at a driving RF frequency of 20 GHz into ~ 2.2 ps soliton pulses using DRA in a 20 km DDF. The generation of high quality of soliton pulses from the 40 GHz sinusoidal beat signal is readily achieved with a significantly enhanced efficiency using DDF based DRA, compared to the case of using a DDF without DRA or a DSF with DRA.
Structure of LL-BM123.ALPHA., a new myo-inosamine-2 containing antibiotic. (1977)

The spectrum of myo-inosamine-2 HCI shows four signals at 56.1 (C2"), 68.2 (C1", C3"), 72.6 (C4", C6") and 74.1 (C5"). These assignments are based on intensity and chemical shift values.
Innovative re-creation of realities in a holographic digital form (2014)

Only nature can create, whereas humans can only re-create. This article is an exploration of synergies between art and science in digital holography in relation to art practice and the making of holograms as art works. This is achieved through involvement in the re-creation of a real object (a telescope) as a case study. A digital three-dimensional model suitable for holographic hard copy re-creation is produced. To explore special and immersive environment, real geographical landscape background from Google Earth is added to the model. After a brief introduction to visual art within the context of two and three-dimensional imaging in the form photography and holography, the whole process of producing the three-dimensional model and the environment in which it should be presented, ready for holographic printing is explained.
Bonded aluminum for auto bodies (1987)

When ferrous materials were replaced by aluminum alloys on already-designed vehicles, part weight halved, and the price doubled for bolted-on parts. However, when aluminum is an integral part of an initial design, its lower mass can help to decrease that of other parts used to support it. Decreased vehicle weight can improve fuel economy, so residual cost premiums can be recovered over a vehicle lifetime, the time required decreasing with increasing fuel costs. Several firms in England and the U.S. have been investigating design and manufacturing systems for building automotive structural frames and unibody structures from adhesively bonded sheet aluminum. This article touches some of the important points brought forth in four presentations made during SAE's Annual Congress earlier this year.
Growth of free-standing bulk wurtzite Al Ga1−N layers by molecular beam epitaxy using a highly efficient RF plasma source (2016)

The recent development of group III nitrides allows researchers world-wide to consider AlGaN based light emitting diodes as a possible new alternative deep ultra–violet light source for surface decontamination and water purification. In this paper we will describe our recent results on plasma-assisted molecular beam epitaxy (PA-MBE) growth of free-standing wurtzite AlxGa1−xN bulk crystals using the latest model of Riber's highly efficient nitrogen RF plasma source. We have achieved AlGaN growth rates up to 3 µm/h. Wurtzite AlxGa1−xN layers with thicknesses up to 100 μm were successfully grown by PA-MBE on 2-inch and 3-inch GaAs (111)B substrates. After growth the GaAs was subsequently removed using a chemical etch to achieve free-standing AlxGa1−xN wafers. Free-standing bulk AlxGa1−xN wafers with thicknesses in the range 30–100 μm may be used as substrates for further growth of AlxGa1−xN-based structures and devices. High Resolution Scanning Transmission Electron Microscopy (HR-STEM) and Convergent Beam Electron Diffraction (CBED) were employed for detailed structural analysis of AlGaN/GaAs (111)B interface and allowed us to determine the N-polarity of AlGaN layers grown on GaAs (111)B substrates. The novel, high efficiency RF plasma source allowed us to achieve free-standing AlxGa1−xN layers in a single day's growth, making this a commercially viable process.
A short-term mouse model that reproduces the immunopathological features of rhinovirus-induced exacerbation of COPD (2015)

Viral exacerbations of chronic obstructive pulmonary disease (COPD), commonly caused by rhinovirus (RV) infections, are poorly controlled by current therapies. This is due to a lack of understanding of the underlying immunopathological mechanisms. Human studies have identified a number of key immune responses that are associated with RV-induced exacerbations including neutrophilic inflammation, expression of inflammatory cytokines and deficiencies in innate anti-viral interferon. Animal models of COPD exacerbation are required to determine the contribution of these responses to disease pathogenesis. We aimed to develop a short-term mouse model that reproduced the hallmark features of RV-induced exacerbation of COPD. Evaluation of complex protocols involving multiple dose elastase and lipopolysaccharide (LPS) administration combined with RV1B infection showed suppression rather than enhancement of inflammatory parameters compared with control mice infected with RV1B alone. Therefore, these approaches did not accurately model the enhanced inflammation associated with RV infection in patients with COPD compared with healthy subjects. In contrast, a single elastase treatment followed by RV infection led to heightened airway neutrophilic and lymphocytic inflammation, increased expression of tumour necrosis factor (TNF)-α, C-X-C motif chemokine 10 (CXCL10)/IP-10 (interferon γ-induced protein 10) and CCL5 [chemokine (C-C motif) ligand 5]/RANTES (regulated on activation, normal T-cell expressed and secreted), mucus hypersecretion and preliminary evidence for increased airway hyper-responsiveness compared with mice treated with elastase or RV infection alone. In summary, we have developed a new mouse model of RV-induced COPD exacerbation that mimics many of the inflammatory features of human disease. This model, in conjunction with human models of disease, will provide an essential tool for studying disease mechanisms and allow testing of novel therapies with potential to be translated into clinical practice.
Communicative interactions between subpopulations of human T lymphocytes required for generation of suppressor effector function in a primary antibody response. (1982)

The cellular interactions necessary for generation of human T suppressor effector function were examined in a primary in vitro antigen-specific anti-DNP antibody-forming system. During the induction of the anti-DNP response, it was found that T cells of both T4+ and T8+ subsets were necessary to suppress antibody formation, whereas after activation, only the T8+ subset was required. Thus, a population of T4+ T cells appears to be necessary to activate or induce a subset of T8+ cells to suppress. The T4+ suppressor inducer population, like the resting or activated T8+ suppressor effector subset, was sensitive to low dose irradiation. Moreover, the radiosensitive T4+ subset and the previously defined T4+JRA+ subset were shown to be functionally similar or complementary in that both were required for generation of suppressor effector function. These findings suggest that T-T interactions between radiosensitive T4+JRA+ T cells and radiosensitive T8+ T cells are necessary for suppression of primary antigen-specific antibody production in man.
Functional Assessment at the Buttock Level of the Effect of Aortobifemoral Bypass Surgery (2008)

A significant increase in MWD and ABI, but little improvement of proximal perfusion is observed after surgery, a finding that is expected from the absence of hypogastric artery revascularization. The prevalence of proximal claudication and proximal blood flow impairment is higher in case of end-to-end when compared with end-to-side proximal aorto-graft anastomosis, confirming the role of collaterals such as lumbar arteries in the buttock circulation during exercise in patients suffering from peripheral arterial disease. Proximal claudication on treadmill early after surgery affects almost one third of the patients and must not be underestimated among patients receiving AF2B. Attempts at hypogastric artery revascularization, if possible, might be preferable to decrease the risk of proximal claudication after AF2B.
Viral proteins containing the purine NTP-binding sequence pattern (1989)

A compilation is presented of viral proteins containing the NTP-binding sequence pattern, and criteria are suggested for assessment of the functional significance of the occurrence of this pattern in protein sequences. It is shown that the distribution of NTP-binding pattern-containing proteins through the viral kingdom is strongly non-random. Sequence comparisons led to delineation of several families of these proteins, some of which could be brought together into superfamilies including also cellular proteins. The available biochemical evidence is compatible with the proposal that viral proteins in which the NTP-binding pattern is evolutionarily conserved might all be NTPases involved in: i) duplex unwinding during DNA and RNA replication, transcription, recombination and repair, and possibly mRNA translation; ii) DNA packaging, and iii) dNTP generation.
DIAGNOSIS OF HYPERTENSION BASED ON AMBULATORY BLOOD PRESSURE MONITORING (2004)

Hermida, R. C.1; Ayala, D. E.1; Calvo, C.2; Dominguez, M. J.2; Covelo, M.2; Mojon, A.1; Fernandez, J. R.1; Lopez, J. E.2 Author Information
Performance Prediction of High-Temperature CO2 Capture System Utilizing Lithium Silicate for Pulverized Coal-Fired Power Plant (2005)

Lithium silicate is a solid CO2-sorbent that can be used repeatedly, and uniquely features absorption of CO2 at temperatures between 500°C and 600°C with an exothermic reaction and regeneration at temperatures above 700°C with an endothermic reaction. This paper introduces the conceptual model and feasibility study of the CO2 capture system utilizing the lithium silicate applicable to a pulverized coal-fired power plant. In this system, assuming a moving bed, the sorbent reactor is installed in a 500MW boiler and absorbs CO2 in the flue gas, and after the absorption process, recirculation of CO2 transports the heat for regeneration. To design the system, unsteady state numerical analysis was used to predict the reactor performance in a 60-minute cycle for absorption and regeneration, which includes the reaction rate based on experimental data. The analysis result indicates that about 20% of CO2 can be captured from flue gas without significant loss in the power generation efficiency.
ChemInform Abstract: Trichothecene Mycotoxin Interconversions: Partial Syntheses of Calonectrin and Deoxynivalenol, and of a Trichothecene epi‐Epoxide, 3α,4β,15‐Triacetoxy‐12,13‐epi‐epoxytrichothec‐9‐ene. (1989)

Abstract The trichothecenes are a group of sesquiterpenoid mycotoxins which show a high degree of largely adverse biological behavior.
Extension of the Amiet theory for compact leading edge airfoil noise prediction (2014)

The Amiet theory is a semi-analytical methodology able to compute the airfoil noise, which is specially applicable to frequencies where the airfoil chord is comparable, or smaller, than the gust hydrodynamic wavelength and, consequently, the airfoil can be considered as a non-compact noise source. For lower frequencies, where the gust wavelength is comparable, or larger, than the airfoil chord, the Amiet theory overpredicts the airfoil noise. This paper discusses the effects of approximations made to the analytical methodology showing that they are partially responsible for the noise superestimation and proposes an iterative procedure of leading and trailing edge correction in order to improve the agreement of this theory with experimental data.
On The Anatomy of the “Nonfacilitating” Features of the Double Auction Institution in Conspiratorial Markets (2018)

Effective conspiracies are more easily formed in posted-offer and in sealed-bid markets than in double auction markets. A feature of double auctions is isolated as the possible source of the behavioral differences. The double auction presents conspirators with continuous temptations to defect from conspiratorial agreements. The chapter argues that the competitive access to buyers of the double auction is a key feature that acts as a nonfacilitating device for conspiracy. The "success" of a conspiracy can be analyzed at five different levels. Do potential agents recognize their common self-interest and explore and discuss conspiracies? Does a conspiracy actually evolve in the sense that agents manage to reach an agreement? Is the agreement implemented? Does the implemented agreement actually influence the market? Are the effects to the advantage of the conspirators? The chapter is concerned with these various possibilities and their relationship to the details of market organization.
Lysyloxidase and benzylamine oxidase in pig aorta. (1981)

Three enzymes were isolated from pig aorta: a benzylamine oxidase differing from the plasma type, and two different types of lysyloxidase. Some properties of the two types of lysyloxidase are described. The three enzymes were inhibited by cupric copper chelating agents and by carbonyl reagents. They did not cross-react with the antibodies to pure pig plasma benzylamine oxidase.
Sonar characterization of tissue as applied to the lung. (1976)

Thesis. 1976. Sc.D.--Massachusetts Institute of Technology. Dept. of Electrical Engineering and Computer Science.
Study of Turbulent Flows of Dilute Polymer Solutions in a Couette Viscometer (1966)

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Physiological coupling of growth factor and steroid receptor signaling pathways: estrogen receptor knockout mice lack estrogen-like response to epidermal growth factor. (1996)

Past studies have shown that epidermal growth factor (EGF) is able to mimic the uterotropic effects of estrogen in the rodent. These studies have suggested a "cross-talk" model in which EGF receptor (EGF-R) signaling results in activation of nuclear estrogen receptor (ER) and its target genes in an estrogen-independent manner. Furthermore, in vitro studies have indicated the requirement for ER in this mechanism. To verify the requirement for ER in an in vivo system, EGF effects were studied in the uteri of ER knockout (ERKO) mice, which lack functional ER. The EGF-R levels, autophosphorylation, and c-fos induction were observed at equivalent levels in both genotypes indicating that removal of ER did not disrupt the EGF responses. Induction of DNA synthesis and the progesterone receptor gene in the uterus were measured after EGF treatment of both ERKO and wild-type animals. Wild-type mice showed increases of 4.3-fold in DNA synthesis, as well as an increase in PR mRNA after EGF treatment. However, these responses were absent in ERKO mice, confirming that the estrogen-like effects of EGF in the mouse uterus do indeed require the ER. These data conclusively demonstrate the coupling of EGF and ER signaling pathways in the rodent reproductive tract.
A Novel, Layered Phase in Ti‐Rich SrTiO<sub>3</sub> Epitaxial Thin Films (2014)

Sr2Ti7O14, a new phase, is synthesized by leveraging the innate chemical and thermo-dynamic instabilities in the SrTiO3-TiO2 system and non-equilibrium growth techniques. The chemical composition, epitaxial relationships, and orientation play roles in the formation of this novel layered phase, which, in turn, possesses unusual charge ordering, anti-ferromagnetic ordering, and low, glass-like thermal conductivity.
Pruning ornamental trees and shrubs (1970)

Published 1970. Reprinted February 1983. Facts and recommendations in this publication may no longer be valid. Please look for up-to-date information in the OSU Extension Catalog: http://extension.oregonstate.edu/catalog
Modulation of Natural Killer and Antibody-Dependent Cellular Cytotoxicity by Interferon and Interleukin-2 in Chronic Myeloid Leukemia Patients in Remission (1989)

Our earlier studies demonstrated that about 55% of chronic myeloid leukemia (CML) patients in remission exhibited impaired natural killer (NK) cytotoxicity (low NK responders) while antibody-dependent cellular cytotoxicity (ADCC) of these patients, on chicken red blood cells as targets, was within normal range. In this paper, we have attempted to modulate the NK cytotoxicity of CML patients in remission with interferon (IFN) and interleukin-2 (IL-2) singly or together. ADCC using K562 target-directed monoclonal antibody (MAb) 4.6E10 was also modulated by treating the effectors with IFN or IL-2. Pretreatment of nonadherent mononuclear cells from peripheral blood (NAPBMNC) with IFN or IL-2 was found to result in 20 and 21% increase in target cell lysis in case of healthy donors, 79 and 98% increase in case of CML normal NK responders, and 164 and 159% increase in case of CML low NK responders. Combined use of IFN and IL-2 potentiated further the lymphocytotoxicity to 25% in healthy donors, 135% in normal NK responder CML patients and 283% in low NK responder CML patients. This treatment resulted in restoration of cytotoxicity of the latter group of patients to a normal level. The augmentation was seen in 80-100% CML patients. Although ADCC with chicken red blood cells as targets was within normal range, ADCC mediated with MAb to K562 cells was significantly lower in CML low NK responders (24.5%) than CML normal NK responders (42.4%) and healthy donors (65.9%).(ABSTRACT TRUNCATED AT 250 WORDS)
ChemInform Abstract: Drastic Solvent Effect on Lipase‐Catalyzed Enantioselective Hydrolysis of Prochiral 1,4‐Dihydropyridines. (1993)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Prognostic, Predictive, and Surrogate Factors for Individualizing Treatment for Men with Castration-Resistant Prostate Cancer (2012)

With the surge in therapeutic options for castration-resistant prostate cancer (CRPC) comes increasingly complicated treatment decision making, highlighting the need for biomarkers that can identify appropriate patients for specific treatments and accurately assess disease response. Here we discuss existing and potential prognostic, predictive, and surrogate biomarkers in CRPC.