gebhart/patrepeval huggingface dataset:
Bandwidth and mode intensities of guided acoustic-wave Brillouin scattering in optical fibers (1993)

The overall bandwidth of guided acoustic-wave Brillouin scattering has been measured in optical fibers with different fiber core diameters. The relative intensity of the light scattering produced by the different acoustic modes is compared with theory and shows good agreement when the optical fiber has its polymer jacket removed. The mode intensities and linewidths in a jacketed optical fiber are modified by the selective damping of individual guided acoustic modes.
Dependence management for dynamic reconfiguration of component-based distributed systems (2002)

The growing popularity of wired and wireless Internet requires distributed systems to be more flexible, adaptive and easily extensible. Dynamic reconfiguration of component-based distributed systems is one possible solution to meet these demands. However, there are some challenges for building dynamically reconfigurable distributed systems. Managing dependencies among components is one of the most crucial problems we have to solve before a system can be dynamically reconfigured at runtime. This paper describes a dependence management for dynamic reconfiguration of distributed systems. The dependence management analyzes not only the static dependencies among components, but also the dynamic dependencies that take place at runtime, in order to support an efficient consistent reconfiguration of distributed systems. In addition, the dependence management can deal with nested dependencies during a dynamic reconfiguration.
Loosely Coupled Traceability for ATL (2005)

Abstract. In the context of model transformation, traceability information may be used in a wide variety of scenarios. Each of them potentially requires a different format or complexity level. Moreover, a single transformation program can be used in several contexts. Consequently, such a program may need to be able to generate different kinds of traceability information. This work aims at showing how traceability can be added to programs written in ATLAS Transformation Language while limiting dependencies to program logic. Model transformation is used to implement this approach. 1
Mechanisms of BK virus infection of renal cells and therapeutic implications (2015)

BK virus (BKV) causes BKV nephritis in renal transplant patients and contributes significantly to the increase of probability of graft loss. BKV, being latent in the urogenital tract, is likely to be transported with the donor kidney to recipients and following reactivation replicates in the nucleus of renal epithelial tubular cells. BKV daughter viruses are released and enter other renal epithelial cells to spread infection. There are still a lot of unknown factors about the mechanism and kinetics of BKV infection. The treatment of BKV infection, with exception of reduction in immunosuppression which increases the risk of allograft rejection, is almost exclusively limited to application of anti-viral drugs with rather inconsistent results. The shortcomings of anti-viral therapies demand the understanding of early steps of infection of permissive cells by BK virus in hope that adequate interventional therapies preventing infection of cells with BK virus could be developed. This review describes the BKV entry in target human cells, intracellular trafficking pathways of BKV particles and potential therapeutic implications based on understanding of mechanisms of BKV infection of renal cells.
More Than Just Sex (1998)

Abstract The purpose of this research was to identify behaviors in addition to those of an explicitly sexual or romantic nature that men and women define as unfaithful acts in the context of committed dating relationships. We also sought to identify possible gender differences in the proportions of men and women who have engaged in these unfaithful behaviors while in dating relationships. We examined 219 college men's and women's reported involvement in sexual behaviors, romantic attachments, sexual and nonsexual fantasies, sexual attraction, romantic attraction, flirting, and social participation in dyads and groups with someone other than their current or past dating partner. A sizable proportion of both men and women reported engaging in one or more of the behaviors at some point in their dating history. Proportionately more men than women indicated having engaged in sexual fantasies of various types about someone other than their primary partner and reported “hitting on” someone else while in a dating relationship. No other gender differences emerged. A unique aspect of this study is that we asked young men and women to determine what kinds of behaviors they considered to be unfaithful rather than only examining sexual and emotional behaviors as has been the case in past research. Further, the few significant gender differences we found indicates that the convergence of men's and women's attitudes about sexuality may now be show in their behavior.
Desiccation‐Tolerant Somatic Embryos of Norway Spruce (<i>Picea abies</i>) Can Be Produced in Liquid Cultures and Regenerated into Plantlets (2001)

A rapid and efficient culture system for Picea abies somatic embryos grown in liquid culture has been developed. Embryogenic cultures grown on semisolid medium (K‐medium) supplemented with auxin (10 μM naphthaleneacetic acid) and cytokinin (5 μM N6‐benzyladenine) for 2–7 yr were used as inoculum for liquid cultures. Liquid cultures were established after 1 mo in liquid K‐medium and were then subcultured to a liquid culture medium supplemented with 16 μM abscisic acid and 7.5% polyethylene glycol (LAP medium) for further development of the somatic embryos. After ca. 2 wk, a large number of well‐formed somatic embryos could be observed. Within 5 wk the embryos had initiated both cotyledons, shoot apical meristem, and radicle. They also accumulated storage proteins, as revealed by immunoblot analysis of a 42‐kDa storage protein and by immunogold labeling of sectioned embryos. By 8 wk, mature somatic embryos had developed. The cell lines were maintained in liquid LAP medium for up to 9 mo. Simultaneously, cultures multiplied and produced embryos that matured. A cell density of 2–3 mL of packed cells to 30 mL culture medium or of 6–8 mL packed cells to 300 mL culture medium was necessary for successful culture. Regeneration capacity of the investigated cell lines was generally stable. Reinitiating embryogenic tissue from mature embryos could also restore this capacity. Embryos that had matured in liquid medium could withstand a high degree of desiccation when subjected to successive reduction of relative humidity, from 90% to 31% over 3 wk. About 40% of the desiccated embryos grew into plantlets after transfer to semisolid medium without added plant growth regulators. They also exhibited an improved morphology of the regenerated plantlets compared to those derived from nondesiccated embryos.
Radiatively Inefficient Magnetohydrodynamic Accretion‐Ejection Structures (2004)

We present magnetohydrodynamic simulations of a resistive accretion disk continuously launching transmagnetosonic, collimated jets. We time-evolve the full set of magnetohydrodynamic equations, but neglect radiative losses in the energetics (radiatively inefficient). Our calculations demonstrate that a jet is self-consistently produced by the interaction of an accretion disk with an open, initially bent large-scale magnetic field. A constant fraction of heated disk material is launched in the inner equipartition disk regions, leading to the formation of a hot corona and a bright collimated, super-fastmagnetosonic jet. We illustrate the complete dynamics of the ``hot'' near steady-state outflow (where thermal pressure $\simeq$ magnetic pressure) by showing force balance, energy budget and current circuits. The evolution to this near stationary state is analyzed in terms of the temporal variation of energy fluxes controlling the energetics of the accretion disk. We find that unlike advection-dominated accretion flow, the energy released by accretion is mainly sent into the jet rather than transformed into disk enthalpy. These magnetized, radiatively inefficient accretion-ejection structures can account for under-luminous thin disks supporting bright fast collimated jets as seen in many systems displaying jets (for instance M87).
Path planning for autonomous underwater vehicles in realistic oceanic current fields: Application to gliders in the Western Mediterranean sea (2009)

Autonomous Underwater Vehicles (AUVs) usually operate in ocean environments characterized by complex spatial variability which can jeopardize their missions. To avoid this, planning safety routes with minimum energy cost is of primary importance. This work revisits the benefits, in terms of travelling time, of path planning in marine environments showing spatial variability. By means of a path planner presented in a previous paper, this work focuses on the application to a real environment of such techniques. Extensive computations have been carried out to calculate optimal paths on realistic ocean environments, based on autonomous underwater glider properties as the mobile platform. Unlike previous works, the more realistic and applied case of an autonomous underwater glider surveying the Western Mediterranean Sea is considered. Results indicate that substantial energy savings of planned paths compared to straight line trajectories are obtained when the current intensity and the vehicle speed are comparable. Conversely, the straight line path betwe en starting and ending points can be considered an optimum path when the current speed does not exceed half of the vehicle velocity. In both situations, benefits of path planning seem dependent also on the spatial structure of the current field. Copyright © 2009. SEECMAR.
Na-K-2Cl cotransporter inhibition impairs human lung cellular proliferation (2004)

The widespread presence of the Na-K-2Cl (NKCC) cotransporter protein suggests that chronic administration of inhibitors may result in adverse effects. Inhibition of the NKCC cotransporter by loop diuretics is felt to underlie the diuretic and the pulmonary smooth muscle relaxant effects of this drug class. However, the fundamental regulation of salt and water movement by this cotransporter suggests that it may also mediate cell volume changes occurring during cell cycle progression. Thus we hypothesized that NKCC cotransporter inhibition by loop diuretics would decrease cellular proliferation. Normal human bronchial smooth muscle cells (BSMC) showed a significant concentration-dependent decrease in cell counts after 7 days of exposure to both bumetanide (n=5-10) and furosemide (n=6-16) compared with controls. Proliferation was similarly inhibited in normal human lung fibroblasts (n=5-9). To determine whether this was due to loss of cells, we performed apoptosis assays on BSMC. Both annexin V-propidium iodide staining (n=5-10) and single cell gel electrophoresis assays (n=4) were negative for necrosis and apoptosis in BSMC exposed to 10 microM bumetanide. Subsequent analysis of the cell cycle by flow cytometry showed that bumetanide-exposed BSMC were delayed in G1 phase compared with controls (n=4-8). This is the first evidence for loop diuretic inhibition of airway smooth muscle cell proliferation. NKCC cotransporter inhibition impeded G1-S phase transition without facilitating cell death. Thus although inhibition by loop diuretics relaxes airway smooth muscle, the NKCC cotransporter may have a more important role in cell proliferation regulation.
Mutanase induction in Trichoderma harzianum by cell wall of Laetiporus sulphureus and its application for mutan removal from oral biofilms. (2008)

The cell wall material from fruiting bodies of Laetiporus sulphureus has been suggested as a new alternative to mutan for the mutanase induction in Trichoderma harzianum. Structural analyses revealed that the alkali-soluble wall fraction from this polypore fungus contained 56.3% of (1-->3)-linked alpha-glucans. When the strain T. harzianum F-340 was grown on a cell wall preparation from L. sulphureus, the maximal enzyme productivity obtained after 3 days of cultivation was 0.71 U/ml. This yield was about 1.8-fold higher than that achieved on mutan, known so far as the best, but expensive and inaccessible, inducer of mutanase production. Cell-wall-induced mutanase showed a high hydrolytic potential in reaction with a dextranase-pretreated mutan, where maximal degrees of saccharification and solubilization of this biopolymer (80% and 100%, respectively) were reached in 3 h at 45 degrees C. The mutanase preparation was also effective in degradation of streptococcal mutan and its removal from oral biofilms, especially in a mixture with dextranase.
Genetic Programming of Minimal Neural Nets Using Occam's Razor (1993)

S.342-351
Abstract 12771: When Auto-Antibodies Potentiate: The Paradoxical Signalling Role of Anti-HSP27 Auto-Antibody Immune Complexes Improves Athero-Protection (2014)

Introduction: While we recently demonstrated that elevated serum levels of the Heat Shock Protein (HSP27) are athero-protective (JACC 2013), we are cognizant of the presence of anti-HSP27 auto-antibodies in human serum that, intuitively, might attenuate the salutary functions of this protein. Interestingly, we note higher levels of anti-HSP27 auto-antibodies in healthy controls compared to CAD patients.

Hypothesis: Taking an iconoclastic perspective, we posit that auto-antibodies to HSP27 function to enhance the athero-protective effects of HSP27.

Methods / Results: Briefly, we reassessed a number of the mechanistic published parameters of the athero-protective effects of HSP27 but now in the presence of anti-HSP27 auto-antibodies. 

Conclusion: Anti-HSP27 auto-antibodies enhance the athero-protective effects of HSP27 by augmenting internalization of the protein, increasing NF-kB signalling and unexpectedly producing a less inflammatory cellular milieu. Hence, there is the potential to develop HSP27 immunization strategies for the prevention and/or treatment of atherosclerosis.
Chloroquine Is a Zinc Ionophore (2014)

Chloroquine is an established antimalarial agent that has been recently tested in clinical trials for its anticancer activity. The favorable effect of chloroquine appears to be due to its ability to sensitize cancerous cells to chemotherapy, radiation therapy, and induce apoptosis. The present study investigated the interaction of zinc ions with chloroquine in a human ovarian cancer cell line (A2780). Chloroquine enhanced zinc uptake by A2780 cells in a concentration-dependent manner, as assayed using a fluorescent zinc probe. This enhancement was attenuated by TPEN, a high affinity metal-binding compound, indicating the specificity of the zinc uptake. Furthermore, addition of copper or iron ions had no effect on chloroquine-induced zinc uptake. Fluorescent microscopic examination of intracellular zinc distribution demonstrated that free zinc ions are more concentrated in the lysosomes after addition of chloroquine, which is consistent with previous reports showing that chloroquine inhibits lysosome function. The combination of chloroquine with zinc enhanced chloroquine's cytotoxicity and induced apoptosis in A2780 cells. Thus chloroquine is a zinc ionophore, a property that may contribute to chloroquine's anticancer activity.
Acetylator phenotype and adverse effects of sulphasalazine in healthy subjects (1972)

Sulphasalazine (salicyl-azo-sulphapyridine) was ingested by 27 healthy subjects for five days at a dosage of 4 g daily. The acetylator phenotype of each subject had been established previously. The serum concentrations of the parent drug and its sulphapyridine-metabolites were determined and the adverse effects were recorded. There was no correlation between the serum concentrations of sulphasalazine and the adverse effects. The slow acetylators obtained enhancement of serum concentrations of sulphapyridine earlier than the rapid acetylators. They also reported adverse effects earlier and of more pronounced nature than the rapid acetylators. The data as a whole suggest that the adverse effects observed were caused by the metabolite sulphapyridine and that they are influenced by the polymorphic acetylation.
Effect of Oil Composition on Minimum Miscibility Pressure—Part 2: Correlation (1987)

Summary A new correlation for CO2 minimum miscibility pressure (MMP) is proposed and tested. The correlation is based on experimental evidence that extraction of hydrocarbons from a crude oil depends most strongly on the size of the hydrocarbon molecules. Thus, an oil rich in hydrocarbons that are efficiently extracted should show a lower MMP than a heavier oil. The only crude-oil data needed for use of the correlation are a carbon-number distribution, which can be obtained easily by chromatography. The density of CO2 at the MMP is correlated against a weighted-composition parameter. The MMP of any oil at a given temperature is estimated as the pressure required to yield that CO2 density. The effects of contaminants in CO2 can be estimated easily by calculating the pressure required to give a mixture density equal to that required for pure CO2. Correlation accuracy was tested by comparing predicted and measured MMP's for 35 oils. The proposed correlation produces MMP estimates accurate to within about 10% for most oils. Comparison of correlation predictions with those of other commonly used correlations indicates that the proposed correlation is significantly more accurate, particularly for recombined oils.
SEVERITY OF BLUNT CHEST TRAUMA IN PATIENTS WITH MULTIPLE (1993)

The Journal of Trauma: Injury, Infection, and Critical Care: August 1993 - Volume 35 - Issue 2 - p 322
Two simple methods for deformation demonstration and measurement (1981)

A problem in the area of the investigation of structural behaviour is the elastic plastic deformation in the vicinity of disturbances like crack tips. Intrinsically the deformation can be measured by measuring the deformation of a grid on the surface in the vicinity of the disturbance. The paper describes a new simple grid system. The grid system consists of the picture layer of a selected photo printing paper. The picture layer is pealed off its carrier and is bonded on the polished specimen surface by means of a fresh cyanoacrylate cement. This system can sustain deformations up to 40% and has a very good contrast. A square grid is bonded on the local surface, the grid is photographed at several load values and later the negatives are magnified and read by means of an image analyser. A relevant question arising in the investigation of the buckling of a metal sheet with Z‐section stringers is how the sheet and the stringers deform relative to each other. This is answered by bonding drinking straws perpendicular to the surface of the specimen at several locations. When the surface rotates out of plane the free ends of the straws show relatively large displacements which have been recorded by means of a 35 mm film camera. The free ends of the straws have been provided with small white disks with central black dots. Films are read by means of an image analyser. Very small differences in rotations between the stringer heads and the sheet can be detected before the specimen collapses.
Teilchenphysik: Das BABAR‐Experiment: CP‐Verletzung in B‐Mesonen‐Zerfällen als Test des Standardmodells (1999)

Abstract In diesem Monat wird der Aufbau des BABAR‐Detektors im SLAC‐Laboratorium (Stanford, USA) abgeschlossen. In internationaler Kollaboration werden dann etwa 500 Physiker der aufregenden Frage nachgehen, ob die seit 1964 bekannte kleine Asymmetrie zwischen Teilchen und Antiteilchen „auch nur”︁ ein Phänomen des Standardmodells der Elementarteilchenphysik ist oder ob sich hier „Neue Physik”︁ zeigt. An den Elektron‐Positron‐Speicherring PEP‐II, der BABAR mit B‐Mesonen versorgt, werden völlig neue Anforderungen gestellt. Auch muß wegen der großen erwarteten Ereignisrate die Datenerfassung und ‐verarbeitung des Experimentes völlig neue Wege beschreiten.
KITSS-a functional software testing system using a hybrid domain model (2003)

The knowledge-based interactive test script system (KITSS) automates functional testing in the domain of telephone switching software. KITSS uses novel approaches to achieving several desirable goals. Telephone features can be specified in English by using a statistical parser that is trained in the domains's technical dialect. KITSS will then convert these specifications into a formal representation that is audited for coverage and sanity. To accomplish this, a theorem-prover-based inference mechanism is used, along with a hybrid domain model represented in both a static terminological logic and a dynamic temporal logic. The corrected test is translated into a test language that is run against the switch on a test harness.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Design of Mobile Robot Platform Based on RAM and μC/OS-II (2007)

The platform is layered, modularized, extensible, transplantable and customizable. And it also has the advantages such as compact hardware, low-power, real-time performance and high reliability. It is easy to apply to robot, explosive ordnance disposal robot, ciceroni robot, amusement robot, domestic robot after simple hardware adjustment and software customization.
Guarding the immune system: Suppression of autoimmunity by CD4<sup>+</sup>CD25<sup>+</sup> immunoregulatory T cells (2006)

CD4+CD25+Foxp3+ T cells (CD25+ T regulatory [Treg] cells) are a naturally occurring suppressor T-cell population that regulates a wide variety of immune responses. A major function of CD25+ Treg cells is to inhibit the activity of self-reactive T cells that can potentially cause autoimmune disease. This review examines the recent advances in CD25+ Treg cell biology, with particular focus on the thymic and peripheral development of CD25+ Treg cells, the signals that promote their expansion and maintenance in the periphery and the mechanism by which they mediate their suppressor activity in peripheral lymphoid tissues. An understanding of these issues is likely to facilitate the development of CD25+ Treg-cell-based therapies for the treatment of autoimmune disease.
El fenómeno "danmu" y la participación mediática: comprensión intercultural y aprendizaje de lenguas a través de "El Ministerio del Tiempo" (2019)

Mientras la investigación sobre las plataformas multimedia occidentales, como YouTube, es prolífica e interdisciplinaria, los portales asiáticos siguen siendo desconocidos. El presente trabajo explora este campo analizando los usos juveniles e interculturales de un sistema de visualización popular en Japón y China, conocido como «danmaku» o «danmu». Esta tecnología inserta comentarios dinámicos y contextualizados sobre un fotograma, con varias posibilidades tipográficas. Partiendo de un corpus de 1.590 comentarios sobre «El Ministerio del Tiempo», recogidos de una plataforma de «fandom» con millones de seguidores, este artículo analiza los temas que despiertan más interés entre los fans chinos. El análisis de contenido, que incorpora técnicas de «coding and counting» de las categorías con más intervenciones (n>16), se combina con un análisis del discurso multimodal (serie de TV, plataforma asiática y comentarios de usuarios). Los resultados muestran que los espectadores se interesan por el género cinematográfico (viaje del tiempo), los personajes, la trama, determinados contenidos socioculturales y la lengua española. Sus discusiones abordan cuestiones de interculturalidad, algunas cuestiones que son tabú en China y la cultura «fandom» en Asia. El estudio ilustra las potencialidades de participación, comunicación y aprendizaje en las redes sociales asiáticas, y supone una aportación interesante e innovadora al campo de la alfabetización mediática y digital, con varias sugerencias para fomentar la competencia intercultural con el uso de la cultura popular.