gebhart/patrepeval huggingface dataset:
Platelet Adhesion to Polymer Coated Drugeluting Stents: AN in-Vitro Study (1995)

Conference Abstract| July 01 1995 Platelet Adhesion to Polymer Coated Drugeluting Stents: AN in-Vitro Study RK Aggarwal; RK Aggarwal 1Department of Cardiology, University of Leicester Search for other works by this author on: This Site PubMed Google Scholar DC Ireland; DC Ireland 1Department of Cardiology, University of Leicester Search for other works by this author on: This Site PubMed Google Scholar A Ragheb; A Ragheb †Med Institute, West Lafayette, In., USA. Search for other works by this author on: This Site PubMed Google Scholar DP De Bono; DP De Bono 1Department of Cardiology, University of Leicester Search for other works by this author on: This Site PubMed Google Scholar AH Gershlick AH Gershlick 1Department of Cardiology, University of Leicester Search for other works by this author on: This Site PubMed Google Scholar Clin Sci (Lond) (1995) 89 (s33): 28P. https://doi.org/10.1042/cs089028Pa Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Share Icon Share Twitter LinkedIn Cite Icon Cite Get Permissions Citation RK Aggarwal, DC Ireland, A Ragheb, DP De Bono, AH Gershlick; Platelet Adhesion to Polymer Coated Drugeluting Stents: AN in-Vitro Study. Clin Sci (Lond) 1 July 1995; 89 (s33): 28P. doi: https://doi.org/10.1042/cs089028Pa Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search nav search search input Search input auto suggest search filter All ContentAll JournalsClinical Science Search Advanced Search This content is only available as a PDF. © 1995 The Biochemical Society and the Medical Research Society1995 Article PDF first page preview Close Modal You do not currently have access to this content.
An approach towards feature location based on impact analysis (2008)

System evolution depends greatly on the ability of a maintainer to locate these parts of the source code that implement specific features. Until recently, quite a number of feature location techniques have been proposed. These techniques suffer from a number of limitations. They either require exercising several features of the system, or rely heavily on domain experts to guide the feature location process. In this thesis, we present a novel approach for feature location that combines static and dynamic analysis techniques. An execution trace is generated by exercising the feature under study (dynamic analysis). A component dependency graph (static analysis) is used to rank the components invoked in the trace according to their relevance to the feature. Our ranking technique is based on the impact of a component modification on the rest of the system. We hypothesize that the smaller the impart of a component modification, the more likely it is that this component is specific to the feature. The proposed approach is automatic to a large extent relieving the user from any decision that would otherwise require extensive knowledge of the system. We present a case study involving features from two software systems to evaluate the applicability and effectiveness of our approach.
Single pulse light-in-flight recording by holography (1989)

We have succeeded we believe for the first time, in making a light-in-flight (LIF) recording using one single pulse of a mode-locked frequency doubled Nd:YAG laser. Many experiments made earlier with multiple picosecond pulses have been repeated and the results were the same. New experiments have become possible such as the contouring of a fast moving object and recording through a nonrigid scattering medium. We demonstrate a LIF transmission method for rejecting scattered light which can be developed into a method for diagnostic imaging inside living tissue.
Complexity-outsourced low-latency video encoding through feedback under a sum-rate constraint (2010)

In live video communication, the quality of the video that is encoded on a mobile device is more often than not constrained by the available computational resources. We address this problem by allowing the encoder to “outsource” the encoding complexity to the decoder through the use of feedback, under a sum-rate constraint comprising the weighted sum of the forward and feedback rates. Analysis of such a complexity-outsourced framework using an analytically tractable video model reveals that the feedback rate should be optimally adapted to the video motion characteristics. Application of our framework to real-world video sequences reveals the efficacy of our proposed architecture, with experimental results validating that substantial gains in PSNR are achievable over state-of-the-art fast-search algorithms at a comparable level of complexity. These gains are significant even for mobile live video communication applications over the Internet.
A machine-learning approach for regional photovoltaic power forecasting (2016)

This paper presents a machine-learning approach for regional photovoltaic (PV) power forecasting of up to 2 days ahead with hourly resolution. Physical PV power model is aggregated by geographical clusters and then summed for an entire ISO load zone. Numerical weather prediction (NWP) forecasts provide parameters, such as irradiance, temperature, barometric pressure, and wind speed, which are used as inputs to calculate plane of array (POA) irradiance and PV output power. A machine-learning approach is then developed. Bias correction for calculated power is conducted using linear regression method. During this procedure, categorization in accordance to critical parameters is employed to obtain a fine approximation. With optimized blending coefficients, adaptive mixture of correction results following different NWP methods is introduced to obtain an intelligent and adaptable output power PV forecast. A case study for the period from June 12, 2014 to January 24, 2015 of Southeastern Massachusetts (SEMA) load zone is carried out. Normalized Root Mean Square Error (NRMSE) is 5.28% for day-ahead forecast horizon, which is reduced by 30.6% compared to the baseline that the best individual model is used.
EFFECTS OF UNIAXIAL ORIENTATION AND MOLECULAR CONFORMATION ON THE MOLECULAR MOTIONS OF NYLON-6 (1965)

The temperature spectra of the dynamic mechanical properties of Nylon-6 monofila-ments of different draw ratios and with α, γ and γ + α forms of chain conformation in the crystalline region, were determined over a temperature range extending from -150° to + 170℃ by using the resonanting reed method in audio frequencies. In addition to the three internal friction peaks known in the literature, i.e. -110℃ (βa), ?40℃ (β'a) and 50℃ (αa), a new loss peak at 130℃ was observed for Nylon-6 in γ-form containing monomer and oligomers.According to the experimental results, the temperature of αa-peak for samples in α-form is higher than those in r-form, that means that chain segments in the γ-form have higher mobility than those in the a-form. The loss peak β'a was greatly enhanced when iodine was absorbed in the fibre. This supports the view that the β'a peak is connected with the motion of chain segments containing free amide groups. The β'a-peak also grows rapidly with orientation, indicating the possible breaking up of hydrogen bonds during the stretching process.The new internal friction peak α'c was found in γ-forms only. The peak height decreased rapidly with increasing draw ratio and vanished at a draw ratio of 3.8. Experimental results indicate that the α'c loss peak is due to molecular motions of the segments in the crystalline region in γ-conformation.
Heparin binds to <i>Leishmania donovani</i> promastigotes and inhibits protein phosphorylation (1989)

We show that promastigotes of Leishmania donovani, the causative agent of visceral leishmaniasis (kala-azar), possess heparin receptors on their surface. From a linear Scatchard plot of the binding data obtained using [3H]heparin and viable promastigotes, one derives a binding constant of 4.7 x 10(-7) M and an estimate of 860,000 receptors per parasite. The [3H]heparin bound to parasites could not be displaced by hyaluronic acid or by three other glycosaminoglycans (dermatan sulphate, chondroitin 4-sulphate and chondroitin 6-sulphate). It was demonstrated that exponential phase promastigotes growing in medium 199 supplemented with fetal bovine serum incorporate 35SO4 into a cell-associated macromolecule that has the properties of heparin proteoglycan. Heparin inhibits the activity of the cell-surface histone-protein kinase; incubation of viable promastigotes with [gamma-32P]ATP and MgCl2 (10 mM) in the absence and presence of heparin (0.01-0.5 mg/ml) for 10 min, followed by analysis by SDS/polyacrylamide-gel electrophoresis and autoradiography, revealed that the phosphorylation of 12 or 13 parasite proteins was inhibited by the glycosaminoglycan. These data suggest that heparin may play a role in the host-parasite relationship.
Imaging through Fog Using Polarization Imaging in the Visible/NIR/SWIR Spectrum (2017)

Abstract : This Phase I effort sought to develop a passive, electric-optical and infrared (EO-IR) imagingsystem. This system employs jointly optimized multi-modal image acquisition and processingmethods in order to increase the operational range (the distance between the sensor and theobject/scene of interest) by 10X over a baseline range that corresponds to traditional, singlemodeimage acquisition in the presence of obscurants. Because the gain in image qualityassociated with a single optimization technique may be modest, a multi-modal hardware solutioncombined with coordinated processing techniques was tested during this effort in order toachieve an exponentially more substantial improvement.
Filtration Based DNA Preparation for Sexual Assault Cases (2003)

Police departments in the United States currently have as many as 500,000 unprocessed swabs taken from rape victims. The standard method for purifying sperm from these swabs is to resuspend first all cells and to digest selectively the excess of the victim's epithelial cells. The intact sperm are then separated from the contaminating solubilized DNA by centrifugation, careful removal of supernatant, and extensive washing of the sperm pellet, all steps that are difficult to automate. Vacuum driven filtration is an alternative method for separating sperm from digested epithelial cells that requires only pipetting steps and can be readily automated in a 96 well format. Sperm DNA is enriched 45-fold using this process and the yield of PCR ready DNA is roughly 20% of the amount originally present on the swab.
THE ROLES OF RETINOIDS IN VERTEBRATE DEVELOPMENT (1995)

Several lines of experimentation suggest that endogenous retinoids, metabolites of vitamin A, play a role in the anterior/posterior development of the central body axis and the limbs of vertebrates. High levels of endogenous retinoids have been detected in proximity to these developing axes in a variety of vertebrate fetuses. Teratogenesis studies suggest that both retinoid excess and deficiency are capable of disrupting the development of these axes. Finally, retinoic acid receptors regulate many developmental control genes, including homeobox genes and growth factor genes.
Patterning artificial lipid bilayer on nanostructured surfaces (2018)

Artificial lipid bilayer on solid substrate plays an important role as an interface between nanotechnology and biology. In this study, grid structures were patterned on Au-Nb-glass substrate and artificial bilayer was prepared on these structures. The fluidity was checked using fluorescence recovery after photobleaching (FRAP), and neuronal adhesion was monitored on such structure using EphrinA5-tethered lipid bilayer. EphrinA5 is a ligand that binds to the Eph receptors of rat cortical neurons and influences cellular adhesion. Our result elucidated that influence of these nanopatterned protein-tethered lipid bilayer on cellular guidance and signaling can address many underlying mechanisms of cellular functioning and help us to understand and differentiate the signaling procedure in cancer and neurodegenerative diseases.
Diffusion imaging in humans at 7T using readout‐segmented EPI and GRAPPA (2010)

Anatomical MRI studies at 7T have demonstrated the ability to provide high-quality images of human tissue in vivo. However, diffusion-weighted imaging at 7T is limited by the increased level of artifact associated with standard, single-shot, echo-planar imaging, even when parallel imaging techniques such as generalized autocalibrating partially parallel acquisitions (GRAPPA) are used to reduce the effective echo spacing. Readout-segmented echo-planar imaging in conjunction with parallel imaging has the potential to reduce these artifacts by allowing a further reduction in effective echo spacing during the echo-planar imaging readout. This study demonstrates that this approach does indeed provide a substantial improvement in image quality by reducing image blurring and susceptibility-based distortions, as well as by allowing the acquisition of diffusion-weighted images with a high spatial resolution. A preliminary application of the technique to high-resolution diffusion tensor imaging provided a high level of neuroanatomical detail, which should prove valuable in a wide range of applications.
Phase Ib trial of bryostatin 1 in patients with refractory malignancies. (1998)

A Phase Ib trial of bryostatin 1, a macrocyclic lactone and protein kinase C (PKC) activator, was conducted in patients with refractory nonhematological malignancies with the primary goal of determining whether down-regulation of peripheral blood mononuclear cell (PBMNC) PKC activity could be achieved in vivo in humans. Patients (four patients/cohort) received bryostatin 1 (25 microg/m2) as a 1-h infusion weekly three times every 4 weeks, but to study the schedule dependence of pharmacokinetics and pharmacodynamics, the first dose was administered according to one of three schedules: (a) a 1-h infusion; (b) a 24-h infusion; or (c) a split course (12.5 microg/m2 as a 30-min infusion) on days 1 and 4. Conventional toxicities (grades I-III) included myalgias, fever, anemia, fatigue, phlebitis, and headache; in addition, two patients in cohort 3 experienced transient elevations in liver function tests, although these patients had preexisting liver metastases. No objective clinical responses were encountered. Effects on PBMNC PKC activity were heterogeneous. Several patients in cohorts 1 and 2 experienced significant declines in activity (approximately 50%) that were sustained in some cases for periods of > or = 72 h. Comparison of 72-h with baseline values for all three patient cohorts combined revealed a trend toward PKC down-regulation (P = 0.06; signed rank test). For each schedule, plasma bryostatin 1 levels were below the level of detection of a platelet aggregation-based bioassay (3-4 nm). Bryostatin 1 administration failed to produce consistent alterations in lymphocyte immunophenotypic profiles, interleukin 2-induced proliferation, or cytotoxicity, although two of three samples from patients in cohort 3 did show significant posttreatment increases in proliferation. Moreover, in some patients, bryostatin 1 treatment increased lymphokine-activated killer cell activity. These findings indicate that bryostatin 1 doses of 25 microg/m2 can induce in vivo PBMNC PKC down-regulation in at least a subset of patients and raise the possibility that higher bryostatin 1 doses may be more effective in achieving this effect.
Particle Size Modification of Thermally Stable Secondary Explosives for IM Applications (2008)

Abstract As well as improving the survivability of weapons and platforms, insensitive munitions (IM) reduce both casualty rates and mission losses. Their use also leads to improved safety during storage and transportation. For a munition to fulfil IM criteria, each of its energetic sub‐sections must be IM compliant. The initiator and explosive train are the most critical of these sub‐systems as their safety and reliability are of paramount importance if the weapon is to be suitable for service use, yet they are generally the most difficult part of a weapon to protect from inadvertent initiation. As part of an ongoing study into initiation methods suitable for use in IM systems, an investigation into the behaviour of energetic materials when impacted by laser‐driven flyers was performed. Laser‐based detonators exhibit increased safety characteristics over conventional initiation methods as they can be based on insensitive secondary explosives rather than sensitive primary explosives. Also, they are less susceptible to accidental initiation due to an external hazard threat. Single pulses from a high‐powered Q‐switched Nd:YAG laser were used to launch flyers from substrate‐backed aluminium films to velocities up to 6 km s −1 across a short stand‐off to impact explosive targets. Several novel energetic materials have been selected for investigation as potential candidates for inclusion within flyer‐based initiation systems and explosive train applications. The materials are of interest due to their increased thermal stability and power output over conventional explosives currently in service. Attempts were made to increase the flyer responsiveness of the materials by tuning their particle size using ultrasound. The effect of particle size on the initiation threshold energy was investigated for three materials.
Combination Ethacizin and Ethmozin Treatment of Resistant Ventricular Ectopy (1994)

Summary: Ethmozin (Moricizine HCl) and ethacizin are two class I antiarrhythmic drugs with different rate constants of interaction with the sodium channel. Computer simulation using the “guarded-receptor” model predicted that the combination of ethacizin and ethmozin should exert a greater decrease in excitability and conduction at short coupling intervals, but little effect at normal heart rates (HR). To test this prediction, we measured intraventricular conduction delay in canine hearts in vivo. In agreement with the model, the combination more potently prolonged the delay only at intervals <600 ms as compared with ethacizin alone. Combination therapy was tested in 6 patients with idiopathic ventricular ectopic depolarizations (VEDs). Three patients were resistant to either ethmozin or ethacizin monotherapy, and three could not tolerate effective doses because of side effects. Quantitative continuous ECG monitoring showed that total VEDs in the resistant group decreased 0 and 17 ± 13% for 400 and 800 mg/day ethmozin and 18 ± 12 and 55 ± 12% for 100 and 200 mg/day ethacizin, respectively. Combined therapy with ethmozin (400 mg/day) and ethacizin (100 mg/day) reduced the number of VEDs by 78 ± 2% in these patients without side effects. In the “nonresistant” but intolerant group of patients, use of the combination allowed relief of symptomatic ectopy without side effects. A theoretical model correctly predicted an effective combination of class I antiarrhythmic drugs, one with “fast-off” and one with “slow-off” kinetics, which may provide a general rationale for choosing drug combinations.
ChemInform Abstract: 1,4‐Addition Reactions of Organocuprates with α,β‐ unsaturated Ketones (1995)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Shock Tube Determination of Dissociation Rates of Hydrogen (1962)

The rate of dissociation of hydrogen was determined in noble gas-H2 mixtures over the temperature range 2800° to 5000°K by density measurements in incident shock waves. An x-ray densitometer was used to measure the density profile produced by the shock wave and the dissociation process. The experimental density profiles were compared with calculated profiles which extended from the shock to the equilibrium region to determine the dissociation rates. The three reactions considered were H2+M⇌ lim krkd2H+M,where M can be Xe, H2, and H. The values and error limits of kr=kd/K for these third bodies in cc2 mole—2 sec—1 are 1.5×1018T—1±30%, 3×1018T—1±50%, and 1×1019T—1±50% respectively. The third body efficiencies of H2 and H relative to Xe are 2 and 7. Kr and Ar were found to have the same efficiency as Xe in the hydrogen dissociation process. The temperature dependence of the recombination coefficient could not be determined in these measurements, so the T—1 was arbitrarily selected for all species. These rate coefficients are approximately a factor of 2 larger than the corresponding numbers for oxygen.
Modules and vector spaces (2008)

A summary is not available for this content so a preview has been provided. Please use the Get access link above for information on how to access this content.
ChemInform Abstract: POTENTIOMETRIC AND POLARIMETRIC STUDIES OF COMPLEXATION OF MOLYBDENUM(VI) AND TUNGSTEN(VI) BY ASPARTIC ACID AND GLUTAMIC ACID (1977)

Abstract Die Titeluntersuchungen zeigen, daß im pH‐Bereich von 5 ‐6,Mo(VI) mit den Säuren einen 1:1‐Komplex mit dem MoO 3 ‐Kern bilden.
Accumulative Charge Separation Inspired by Photosynthesis (2010)

Molecular systems that follow the functional principles of photosynthesis have attracted increasing attention as a method for the direct production of solar fuels. This could give a major carbon-neutral energy contribution to our future society. An outstanding challenge in this research is to couple the light-induced charge separation (which generates a single electron-hole pair) to the multielectron processes of water oxidation and fuel generation. New design considerations are needed to allow for several cycles of photon absorption and charge separation of a single artificial photosystem. Here we demonstrate a molecular system with a regenerative photosensitizer that shows two successive events of light-induced charge separation, leading to high-yield accumulation of redox equivalents on single components without sacrificial agents.
Sudden Cardiac Death in Women (2012)

Women are at lower risk for development of sudden cardiac death (SCD) as compared with men. Women with SCD tend to have less structural heart disease and preserved left ventricular systolic function. Coronary artery disease (CAD) is the most common predictor of SCD in women, as it is in men. However, women with SCD are less likely to have underlying CAD than men, suggesting the need to identify risk factors other than CAD or systolic dysfunction for its prediction in women. SCD risk factors in women include heart failure with preserved left ventricular systolic function, abnormal sympathetic uptake as assessed by meta-iodobenzylguanidine uptake, depression, and/or use of antidepressants. This article reviews SCD in women and discusses areas for future research.
Short Randomizable Signatures. (2015)

Abstract. Digital signature is a fundamental primitive with numerous applications. Following the development of pairing-based cryptography, several taking advantage of this setting have been proposed. Among them, the Camenisch-Lysyanskaya (CL) signature scheme is one of the most flexible and has been used as a building block for many other proto-cols. Unfortunately, this scheme suffers from a linear size in the number of messages to be signed which limits its use in many situations. In this paper, we propose a new signature scheme with the same features as CL-signatures but without the linear-size drawback: our signature consists of only two elements, whatever the message length, and our algorithms are more efficient. This construction takes advantage of using type 3 pairings, that are already widely used for security and efficiency reasons. We prove the security of our scheme without random oracles but in the generic group model. Finally, we show that protocols using CL-signatures can easily be instantiated with ours, leading to much more efficient con-structions. 1