gebhart/patrepeval huggingface dataset:
Ethacrynic Acid Effect on the Composition of Cochlear Fluids (1971)

Ethacrynic acid, when administered to six dogs, caused a fall in the concentration of potassium in endolymph from 145 to 21 milliequivalents per liter and a rise in the concentration of sodium from 5.9 to 146 milliequivalents per liter. The composition of perilymph is unaffected. Perilymph and endolymph are slightly hypertonic as compared to plasma.
Mixed Precision Methods for Convergent Iterative Schemes (2006)

Most error estimates of numerical schemes are derived in the field of real or complex numbers. From a computational point of view this assumes infinite precision. For the implementation on a computer, the infinite number fields are quantized into a finite set of
Structural Investigation of Carbosilane Liquid Crystalline Dendrimers (2008)

X-ray and neutron scattering investigations have been made on two series of liquid crystal dendrimers. The low generations (first to fourth) predominantly show smectic phases. The fifth generation shows a tendency to form columnar phases and two different types have been observed. The transition from smectic to columnar has been explained in terms of the distance between the dendritic core and the mesogenic units. As the generation number is increased, the distance increases until it becomes greater than the maximum length of the flexible spacers causing a change in molecular shape and the formation of columnar phases. Although the materials are nearly monodisperse, the small variation in the number of mesogens per molecule gives rise to some subtle structural effects. Two coexisting structures have been observed over large temperature ranges in some materials and small angle neutron scattering indicates that there is some microphase segregation which is a reversible function of temperature.
Accurate photoconductive antenna characterization using a thin film polarizer (2012)

The horizontal and vertical polarizations of the terahertz radiation emitted from a small-gap dipole photo-conductive antenna are characterised using a single detector and a homemade thin-film wire grid polarizer. The two polarizations are seen to be temporally distinct. In addition, the dependence of the position of the excitation spot on the dipole with the polarity of the horizontal polarization is studied where a reversal in the horizontal polarization is observed between the two edges of the antenna anode.
Performances ofGeSnSbTe Material forHigh-Speed Phase Change Memory (2007)

range. FortheGSTdevice, theRESETcurrent seemsnotchange alotwith pulse width, while theSETcurrent showsaslightly increasing trend. Onthe Inthis paper, anewapplication ofphasechange material GeSnSbTe other hand, bothRESETandSETcurrents oftheGSSTdevice decrease as (GSST) isproposed forhigh-speed phase-change memory(PCM). Thedevicethepulse width increases. TheGSSTdevice shows ahigher RESETcurrent characteristics ofPCM employing GeSnSbTe andconventional Ge2Sb2Te5 (A1mA)butalower SETcurrent (-5mA)thanthose oftheGSTdevice. (GST)arecompared. Because ofhighcrystallization speed, theGSSTdeviceThehigher RESETcurrent oftheGSSTdevice maybeattributed toits lower demonstrates thebenefits ofshorter SETpulse, lower SETcurrent, andhigherelectrical resistance, while thelowerSETcurrent maybeexplained bythe resistance ratio. lowercrystallization temperature (GSST1500C, GST1600C) andhigher crystallization speed.
Two-way time transfer experiments using an INTELSAT satellite in a inclined geostationary orbit (1993)

The Communications Research Laboratory (CRL) and Korea Research Institutes of Standards and Science (KRIS) had the opportunity to use satellites for the two-way time transfer experiment. CRL performed two kinds of Intelsat experiments: the ranging experiment and the Japanese domestic experiment. CRL and KRISS also performed a Japan-Korea joint international experiment. The results of these three experiments are described.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Utility of PDL progenitors for in vivo tissue regeneration: a report of 3 cases (2009)

This study demonstrated clinical and experimental evidences supporting a potential efficacy and safety of utilizing autologous PDL cells in the treatment of human periodontitis.
Breaching or Building Social Boundaries? (1998)

Computer-mediated communication (CMC) is sometimes heralded for its power to break down social boundaries and to liberate individuals from social influence, group pressure, and status and power differentials that characterize much face-to-face interaction. We review research conducted within the framework of the social identity model of deindividuation effects (SIDE) demonstrating that this is not always the case. When communicators share a common social identity, they appear to be more susceptible to group influence, social attraction, stereotyping, gender typing, and discrimination in anonymous CMC. Although CMC gives us the opportunity to traverse social boundaries, paradoxically, it can also afford these boundaries greater power, especially when they define self- and group identity.
Autolytic Enzyme System of <i>Streptococcus faecalis</i> IV. Electron Microscopic Observations of Autolysin and Lysozyme Action (1968)

Cell walls (LOG walls) were isolated from cultures of Streptococcus faecalis ATCC 9790 in the exponential phase of growth. These walls were either allowed to undergo autolytic dissolution (in the presence or absence of trypsin) or wall autolysis was inactivated with sodium dodecylsulfate (SDS walls). Inactivated walls were treated either with lysozyme or with isolated, partially purified S. faecalis autolysin. During wall lysis, samples were removed, negatively stained with phosphotungstate, and examined in the electron microscope. Both lysozyme and isolated autolysin appeared to act over the entire surface of SDS walls. After partial dissolution, a fibrous network over the surface was revealed. Lysozyme digestion revealed the presence of prominent, highly-contrasted equatorial and subequatorial bands around the walls. After trichloroacetic acid extraction, the bands were seen less frequently and less distinctly in the partially lysozyme digested walls, suggesting that the bands contained nonpeptidoglycan polymers. In the absence of trypsin (which activates a latent form of the autolysin), autolysis of LOG walls appeared to start at the equatorial bands and to proceed back towards the apex of the coccus. Ribbons of wall material coming off the wide edge of the nearly hemispherical wall fragments were observed. Activation of latent autolysis resulted in lytic action over the entire wall surface. The results are consistent with the previously postulated location of active autolysin at the areas of new wall synthesis and the random location of latent autolysin in LOG walls.
Die angiographische Abklärung der portalen Hypertension im Kindesalter (1972)

Das Ziel der röntgendiagnostischen Abklärung durch die Angiographie bei portalen Hypertensionen besteht im Nachweis der Gefäßobstruktion, in der Beurteilung der Pfortader und des eventuell vorliegenden Kollateralkreislaufes sowie in der Darstellung der postoperativen Situation.
Is suppression of cyst growth in PKD enough to preserve renal function? (2012)

The autosomal dominant form of polycystic kidney disease (ADPKD) is one of the most frequent monogenic disorders and the most frequent among inherited kidney disorders. In fact it has a prevalence in the population of about 1/1,000 individuals, therefore it does not even satisfy the definition for rare diseases. It is mainly characterized by the formation of multiple cysts filled with fluid that over time develop in number and size leading to the distraction of the structure and function of the kidneys and eventually leading to chronic kidney disease/end stage kidney disease (CKD/ESKD), usually between the 4th and 7th decade of life. There are two known forms of the autosomal dominant type of polycystic kidney disease, type 1 and type 2, caused by mutations in the PKD1 and PKD2 genes, located on chromosomes 16 and 4 respectively. The polycystin 1 protein, encoded by PKD1 and mutated in ~85% of patients, is a huge protein of 4,302 amino acids with multiple transmembrane domains, 200 residues intracytoplasmic part and a huge extracellular part with multiple Ig-like PKD repeats, which probably acts as a receptor to an unknown ligand. Polycystin 1 has been shown to interact with and participate in multiple signal transduction pathways, including the G-protein coupled receptor, cAMP pathway, Wnt, mTOR, MAPK/ERK, AP1 and JAK-STAT pathway, while its intracytoplasmic C-terminal domain has been shown to be cleaved and translocated to the nucleus where it plays a role in gene transcription, in concert with P100 and STAT6.(1.)
Innovative trust & security research outputs (2014)

The need to maximise the number of innovative trust and security (T&S) research project outputs impacting the marketplace is an important priority in the EU ICT Security Research Domain. This paper highlights supporting key activities and the CSP Forum initiative that strives to promote and encourage collaboration amongst the relevant security research actors and the wider community. Effective clustering activities such as CSP Forum clustering events helps such funded projects to come together as a community to identify market trends, gaps, issues and solutions. Market analysis is an important activity to work towards gaining successful market acceptance. Projects need to gain an in-depth understanding to enable them to work towards successfully exploiting their outputs and maximising their impact. This paper provides a sample of such success stories coming from the T&S research domain and an insight into the research to industry process, utilised also highlighting example barriers and recommendations for improvement.
Studies on the Interactions Between Mucin and Surfactant Aggregates Containing the Cationic Surfactant Dodecyl Betainate (2009)

The interactions of surfactant aggregates containing the cationic, cleavable surfactant dodecyl betainate (DB) with mucin are investigated. The aggregates were either mixed micelles of DB and the nonionic surfactant PS-80 in different ratios or a dispersion of the commercial self-emulsifying drug-delivery formulation Sandimmun Neoral “charged” with DB. It is found that for the surfactant aggregates to show any notable interactions with mucin these must have a high positive charge density. Also presented are results from Ussing chamber experiments, which suggest that DB has a limited impact on the integrity and the barrier function of the intestinal epithelium.
New Robust and Fragile Watermarking Scheme for Colour Images Captured by Mobile Phone Cameras (2013)

This paper examines and evaluates a new robust and fragile watermarking scheme for colour images captured by mobile phone cameras. The authentication has been checked by using the fragile watermarking, while the copyright protection has been examined by using the robust one. The mobile phone number, including the international code, is a unique number across the whole world and it is used as a robust watermark. The number is embedded in the frequency domain using the discrete wavelet transform. On the other hand, hash codes are used as fragile watermarks and inserted in the spatial domain of the RGB image. The scheme is blind and the extraction process of the watermarks (Robust and Fragile) does not require the original image. The fragile watermark can detect any tampering in the image while the robust watermark is strong enough to survive against several attacks. The watermarking algorithm causes minimal distortion to the images. The proposed algorithm has been successfully tested, evaluated and compared with other algorithms.
Cell Fusion Activity of Hepatitis C Virus Envelope Proteins (2000)

To examine the cell fusion activity of hepatitis C virus (HCV) envelope proteins (E1 and E2), we have established a sensitive cell fusion assay based on the activation of a reporter gene as described previously (O. Nussbaum, C. C. Broder, and E. A. Berger, J. Virol. 68:5411-5422, 1994). The chimeric HCV E1 and E2 proteins, each consisting of the ectodomain of the E1 and E2 envelope protein and the transmembrane and cytoplasmic domains of the vesicular stomatitis virus G glycoprotein, were expressed on the cell surface. Cells expressing the chimeric envelope proteins and T7 RNA polymerase were cocultured with the various target cell lines transfected with a reporter plasmid encoding the luciferase gene under the control of the T7 promoter. After cocultivation, the cell fusion activity was determined by the expression of luciferase in the cocultured cells. The induction of cell fusion requires both the chimeric E1 and E2 proteins and occurs in a low-pH-dependent manner. Although it has been shown that HCV E2 protein binds human CD81 (P. Pileri, Y. Uematsu, S. Campagnoli, G. Galli, F. Falugi, R. Petracca, A. J. Weiner, M. Houghton, D. Rosa, G. Grandi, and S. Abrignani, Science 282:938-941, 1998), the expression of human CD81 alone is not sufficient to confer susceptibility to cell fusion in the mouse cell line. Treatment of the target cells with pronase, heparinase, or heparitinase reduced the cell fusion activity induced by the chimeric envelope proteins. These results suggest (i) that both HCV E1 and E2 proteins are responsible for fusion with the endosomal membrane after endocytosis and (ii) that certain protein molecules other than human CD81 and some glycosaminoglycans on the cell surface are also involved in the cell fusion induced by HCV.
A preliminary investigation of the responsiveness or otherwise of patients and staff of a leprosy hospital to groups of shared or species specific antigens of mycobacteria (1981)

In an attempt to classify skin-test responsiveness of leprosy patients according to the groups of antigens, rather than the individual mycobacterial species to which they respond, we have tested patients and staff members at Anandaban leprosy hospital in Nepal with Burulin (made from My cobacteria ulcerans) and 3 specially mixed re agents. Ability to make a positive response to group i, common mycobacterial antigens, was almost absent and to group ii, antigens associated with slow growers, was markedly impaired in the patient groups. However, positive responses to group iv, species specific, antigens of slowly growing species were re tained. Non-specific skin-test unresponsiveness (Category 2) due either to sequestration of the relevant cells outside the circulation or to circulating suppressor factors was present in 2 out of 27 staff members, 9 out of 24 TT/BT patients, 11 out of 18 BL patients and 10 out of 22 LL patients. Evidence of a suppressor mechanism possibly triggered by group iv antigens of fast growers and operative on positive responses to slow growers, was demonstrable in 3 out of 12 staff members, 8 out of 14 TT /BT patients, 7 out of 7 BL patients and 6 out of 12 L L patients.
Subunit structure of glycogen phosphorylase (1970)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSubunit structure of glycogen phosphorylaseVirginia L. Seery, Edmond H. Fischer, and David C. TellerCite this: Biochemistry 1970, 9, 18, 3591–3598Publication Date (Print):September 1, 1970Publication History Published online1 May 2002Published inissue 1 September 1970https://pubs.acs.org/doi/10.1021/bi00820a014https://doi.org/10.1021/bi00820a014research-articleACS PublicationsRequest reuse permissionsArticle Views44Altmetric-Citations20LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Differential modulation of human multinegative (CD3<sup>−</sup> 4 <sup>−</sup> 8 <sup>−</sup>) thymocyte proliferation by monoclonal antibodies to CD45RA or to CD45 (1994)

Human multinegative (CD3-4-8-19-; MN) thymocytes proliferate optimally in response to anti-CD2 plus anti-CD28 mAb plus PMA or IL-7. The role of CD45 was assessed by the addition of mAb to a CD45 common determinant, or to CD45RA. MN thymocytes are unresponsive to anti-CD2 mAb. Co-stimulation with anti-CD45RA generated 1.6-5.7-fold enhancement of a proliferative response, with maximal enhancement by cross-linkage of CD45RA molecules. The response to anti-CD2/28 mAb was reproducibly enhanced only by immobilized anti-CD45RA. Cross-linking of CD45RA and CD28 through the use of heteroconjugates of mAb did not enhance the co-stimulation by CD45RA. The most marked enhancement by anti-CD45RA occurred in suboptimal activation conditions. In contrast, the response to anti-CD2 or anti-CD2/28 was inhibited by mAb to CD45 common determinants (anti-CD45) in the presence or absence of PMA or IL-7, with the most profound inhibition (6-8-fold) detected in optimal proliferative conditions. Cross-linking of CD45 and CD28 through heteroconjugates of mAb was required as soluble anti-CD45 or immobilized anti-CD45 were unable to mediate inhibition. This inhibitory effect of (anti-CD45 x 28) was specific to MN thymocytes as no inhibition was detectable when peripheral blood T cells were treated with anti-CD2/28 and the same heteroconjugate. The differential effects of anti-CD45 and anti-CD45RA may reflect either CD45 heterogeneity on MN thymocytes, or the physical modulation of a single CD45 molecules by interactions at different epitopes, and the avidity of the relevant CD45 mAb for thymocyte CD45 isoforms may play a role.(ABSTRACT TRUNCATED AT 250 WORDS)
Electrochemical synthesis of poly(3,4‐ethylenedioxythiophene) nanotube arrays using ZnO templates (2010)

Abstract A new method toward vertically oriented poly(3,4‐ethylenedioxythiophene) (PEDOT) nanotube arrays on transparent conductive oxide substrates is presented. The approach is based on the use of ZnO nanowire arrays as templates for the electropolymerization of PEDOT. Robust arrays of vertically oriented PEDOT nanotubes with different lengths and wall thicknesses were obtained by modifying the ZnO nanowire length and charge density passed during the electropolymerization, respectively. Furthermore, PEDOT nanotubes with different morphologies (top‐closed and mushroom‐like) were successfully designed by varying the PEDOT electropolymerization kinetics or monomer diffusion or both. © 2010 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem, 2010
Oxidation of phenols to hydroxycyclohexadienones using diphenylseleninic anhydride (1975)

D. H. R. Barton, P. D. Magnus and M. N. Rosenfeld, J. Chem. Soc., Chem. Commun., 1975, 301 DOI: 10.1039/C39750000301
A Web-Based Chemoinformatics System for Drug Discovery (2004)

One of the key questions that must be addressed when implementing a chemoinformatics system is whether the tools will be designed for use by the expert user or by the "bench scientist." This decision can impact not only the style of tools that are rolled out, but is also a factor in terms of how these tools are delivered to the end users. The system that we outline here was designed for use by the non-expert user. As such, the tools that we discuss are in many cases simplified versions of some common algorithms used in chemoinformatics. In addition, the focus is on how to distribute these tools using a web-services interface, which greatly simplifies delivering new protocols to the end user.
Differential-Gleichungen für Ingenieure: Eine Einführung. By L. Collatz, 2nd Ed. Pp. 197. DM 21.60. 1960. (Teubner, Stuttgart) - Theory and Solution of Ordinary Differential Equations. By D. Greenspan. Pp. viii + 148. 38s. 6d. 1960. (The Macmillan Company, New York) (1961)

Differential-Gleichungen für Ingenieure: Eine Einführung. By L. Collatz, 2nd Ed. Pp. 197. DM 21.60. 1960. (Teubner, Stuttgart) - Theory and Solution of Ordinary Differential Equations. By D. Greenspan. Pp. viii + 148. 38s. 6d. 1960. (The Macmillan Company, New York) - Volume 45 Issue 353
Scheduling Asymmetric Parallelism on a PlayStation3 Cluster (2008)

Understanding the potential and implications of asymmetric multi-core processors for cluster computing is necessary, as these processors are rapidly becoming mainstream components in HPC environments. In this paper we evaluate a Linux cluster of Sony PlayStation3 consoles, using microbenchmarks and bioinformatics applications. We proceed to develop a model and scheduling techniques for effective execution of parallel applications on this low-cost, yet unconventional HPC platform based on the Cell/BE processor. We present an analytical formulation of layered parallelism for clusters of asymmetric multi-core multiprocessors and propose new co-scheduling heuristics for effectively executing MPI code with nested task and data parallelism on these systems. Our model has low execution time prediction error and is reliable in predicting optimal mappings of nested parallelism in MPI programs on the PS3 cluster. The presented co-scheduling heuristics reduce slack time on the accelerator cores of the PS3 and improve the performance of MPI applications by 1.7-2.7x, when compared against the native OS scheduler.
Implantable pacemakers for management of tachyarrhythmias. (1979)

Attempts have been made to control tachyarrhythmias with implantable pacemakers since the late 1960's. The basic approaches considered were: a) maintenance of a basic rate following surgical division of the conducting system, b) pacing to prevent onset of tachyarrhythmias, and c) pacing to terminate episodes of tachyarrhythmias. The earliest approaches required conscious patient interaction in effecting therapy. Emergence of newer technologies has allowed development of flexible, automatic pacing systems which overcome some of the limitations of earlier approaches.
Repetitively Pulsed Electric Laser Acoustic Studies. Volume 1. (1983)

Abstract : This report summarizes a study of the acoustical characteristics of a closed loop duct system for pulsed lasers with emphasis on acoustic suppression technology. Several topics are considered involving wave propagation reflection and attenuation in a shock tube, in which pulse waves are generated, simulating those in a pulsed laser system. A detailed analysis of the design of parallel-baffle attenuators for suppression of acoustic waves is given, allowing for the contributions of the reflection transmitted and reverberant contributions to the sound pressure field in the optical cavity.
Diagnostic approach to small nodules less than 1cm in the lung. (1987)

主径1cm以下の肺野微小陰影を有する15症例について各種診断的アプローチの価値を検討した.CTを含めたX線学的画像診断では約半数に診断的価値が認められた.15例中癌症例は6例あり, いずれも腺癌で, そのうち4例が術前に組織細胞学的に診断された.組織学的に再構築を行った結果, 術前に組織片を採取し得た3例では, いずれも径1.5mm以上の気管支が癌病巣に通じていた.一方, それを採取できなかったものの中には, 気管支のmainstreetからはずれた娘枝から発生したと思われるものがみられた.以上から, 経気管支的に病巣に到達するための新しい診断器具の必要性が示唆された.