gebhart/patrepeval huggingface dataset:
Efficient Distribution of Security Policy Filtering Rules in Software Defined Networks (2020)

Software Defined Networks administrators can specify and smoothly deploy abstract network-wide policies, and then the controller acting as a central authority implements them in the flow tables of the network switches. The rule sets of these policies are specified in the forwarding tables, which are usually accessed using very expensive and power-hungry ternary content-addressable memory (TCAM). Consequently, a given table can only contain a limited number of rules. However, various applications need large rule sets to perform filtering on diverse flows. In this paper, we propose several algorithms for decomposing and distributing a rule set on network switches of limited flow tables size, while preserving the network policy semantics. Through experiments on several rule sets with single and multiple dimensions, we evaluate and analyse the performance of our rule placement techniques. Our results show that our proposals are efficient in practice.
Evaluation of Equivalent Efficacy of Sinemet and Sinemet CR in Patients with Parkinsonʼs Disease Applying Levodopa Dosage Conversion Formula (1999)

We report ease of conversion, effect on equivalent efficacy and frequency of dosing when immediate-release carbidopa/levodopa (Sinemet, IR-CL, DuPont Pharma, Wilmington, DE, U.S.A.) is replaced with controlled-release carbidopa/levodopa (Sinemet CR, CR-CL, DuPont Pharma, Wilmington, DE, U.S.A.) in patients with Parkinson's disease (PD). One-step conversion through the application of a mathematical formula was utilized. Fifty-two patients (35 men, 17 women) with a mean +/- SD age of 72 +/- 8 years participated in this open-label study. All patients were taking IR-CL prior to conversion. The Unified Parkinson's Disease Rating Scale (UPDRS) was used for efficacy assessment. Pharmacokinetic studies were undertaken in five patients while they were on IR-CL, and repeated after they were switched to CR-CL. Dosage adjustment was not required either immediately after converting or during the 6-month follow-up. No significant changes occurred in efficacy scores during follow-up visits, indicating the effectiveness of the conversion. There were substantial differences in the level of plasma DOPA, dopamine, 3-O-methyldopa, homovanillic acid, and dihydroxyphenylacetic acid between patients receiving IR-CL and those receiving CR-CL, but the differences did not correlate with clinical changes, suggesting that plasma levels do not reflect tissue levels at the site of action for levodopa. This study demonstrates that conversion from IR-CL to CR-CL for optimal dosing may be achieved in one step through the application of a mathematical formula with ease of conversion and reduction of number of doses.
Recombination Between Viral RNA and Transgenic Plant Transcripts (1994)

Transformed plants expressing the 3' two-thirds of the cowpea chlorotic mottle virus (CCMV) capsid gene were inoculated with a CCMV deletion mutant lacking the 3' one-third of the capsid gene. Although the deletion inoculum replicates in inoculated cells, systemic infections occur only if recombination restores a functional capsid gene. Four of 125 inoculated transgenic plants, representing three different transgenic lines, became systemically infected. Analysis of viral RNA confirmed that RNA recombination had united the transgenic messenger RNA and the challenging virus through aberrant homologous recombination.
The role of the JAK-STAT pathway and related signal cascades in telomerase activation during the development of hematologic malignancies (2013)

Telomerase, comprising a reverse transcriptase protein (TERT) and an RNA template, plays a critical role during senescence and carcinogenesis; however, the mechanisms by which telomerase is regulated remain to be elucidated. Several signaling pathways are involved in the activation of TERT at multistep levels. The JAK-STAT pathway is indispensable for mediating signals through growth factor and cytokine receptors during the development of hematopoietic cells, and its activity is frequently upregulated in hematological malignancies. Here, we review the role of the JAK-STAT pathway and related signaling cascades in the regulation of telomerase in hematological malignancies.
Utilization of a decision table translator for basic program creation (1971)

article Free Access Share on Utilization of a decision table translator for basic program creation Author: Henry O. Arnold Management Systems Development Office Management Systems Development OfficeView Profile Authors Info & Claims ACM SIGPLAN NoticesVolume 6Issue 8September 1971 pp 12–19https://doi.org/10.1145/953368.953371Online:01 September 1971Publication History 4citation163DownloadsMetricsTotal Citations4Total Downloads163Last 12 Months9Last 6 weeks1 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my Alerts New Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteeReaderPDF
Anti-oestrogen Therapy for Breast Cancer: A Trial of Tamoxifen at Two Dose Levels (1973)

Tamoxifen (ICI 46474) was given by mouth to patients with advanced, recurrent, or metastatic breast carcinoma. At a dosage of 10 mg twice daily 60% of patients showed arrest or reversal of tumour growth. At a dosage of 20 mg twice daily 77% showed arrest or reversal of tumour growth. Side effects were usually trivial and their incidence was the same at both dose levels. No patients showed virilization of fluid retention.
A Pilot Outcome Study of Art Therapy and Music Therapy With Hospitalized Children (Étude pilote des résultats de l'art-thérapie et de la musicothérapie auprès d'enfants hospitalisés) (2016)

This article presents the preliminary results of an outcome study comparing the effectiveness of art therapy and music therapy in a large pediatric medical facility. Measures of pain and mood were taken before and after sessions over two and a half years and across six therapists. The findings suggest that mood improved more effectively after art therapy than after music therapy. Although no significant difference was found in pain measured between modalities, the data indicate that music therapy might be more easily tolerated when patients are experiencing moderate or high levels of pain, as considerably fewer art therapy sessions were completed with patients reporting severe pain. A case illustration and the discussion of findings suggest possible clinical applications for maximizing the impact of expressive treatments in medical settings.
Contents (2016)

Coalmining was a notoriously dangerous industry and many of its workers experienced injury and disease. However, the experiences of the many disabled people within Britain's most dangerous industry have gone largely unrecognised by historians. This book examines the British coal industry through the lens of disability, using an interdisciplinary approach to examine the lives of disabled miners and their families.The book considers the coal industry at a time when it was one of Britain's most important industries, and follows it through a period of growth up to the First World War, through strikes, depression and wartime, and into an era of decline. During this time, the statutory provision for disabled people changed considerably, most notably with the first programme of state compensation for workplace injury. And yet disabled people remained a constant presence in the industry as many disabled miners continued their jobs or took up 'light work'. The burgeoning coalfields literature used images of disability on a frequent basis and disabled characters were used to represent the human toll of the industry.A diverse range of sources are used to examine the economic, social, political and cultural impact of disability in the coal industry, looking beyond formal coal company and union records to include autobiographies, novels and oral testimony. It argues that, far from being excluded entirely from British industry, disability and disabled people were central to its development. The book will appeal to students and academics interested in disability history, disability studies, social and cultural history, and representations of disability in literature.
A wavelet based algorithm for pan sharpening Landsat 7 imagery (2002)

At IGARSS 2000 the Data Fusion Committee began the sponsorship of a series of contests with which the committee aimed to reach two goals. The first goal was to assess the state of the art of a clearly defined aspect of the data fusion field by empirically evaluating algorithms. The second goal was to identify collective weaknesses of current algorithms, so as to identify requirements of further research. The first contest focused in the sharpening of 30-m resolution multispectral images by using 15-m panchromatic imagery. The objective of the sharpening was to improve the spatial resolution of the multispectral imagery, while preserving the spectral information in homogeneous areas. For the IGARSS 2000 contest, Landsat 7 Thematic Mapper data acquired over urban and agricultural areas was used. Researchers from the Remote Sensing Technologies Center at Mississippi State University won the contest. This paper describes the pan sharpening methodology used.
UM RITUAL NA VIDA DO POVO RAMKOKAMEKRÁ CANELA: CORRIDA COM TORA (2019)

Faz-se uma relação da música com a Corrida com Tora, por serem os rituais mais rotineiros e cotidianos na vida do povo Ramkokamekrá Canela. Em linhas gerais, situa-se os principais aspectos culturais dos Ramkokamekrá, fala-se da Corrida com Tora e sua utilização no dia-a-dia e nas festividades. Descreve-se e analiza-se as principais músicas utilizadas no ritual da Corrida com Tora.
ADVANCE: INITIAL DEPLOYMENT (1995)

The Advanced Driver and Vehicle Advisory Navigation Concept (ADVANCE) project is a large advanced traveler information system (ATIS) demonstration project located in the northwest suburbs of Chicago, Illinois. This paper focuses on the current status of the ADVANCE system. Integration is now occurring on the five subsystems that will result in acceptance of an integrated system ready for installation in vehicles commencing in the late spring of 1995. Extensive testing has been performed on the dynamic capabilities of the subsystems, with the result that some algorithms have required retuning. Driver recruitment has now begun with development of criteria for selection and development of a project database. The first 30 drivers have been selected.
Hydraulic characterization and upscaling of fracture networks based on multiple‐scale well test data (2000)

Hydraulic properties and upscaling characteristics of low‐permeability fractured rock are analyzed based on systematic well test data from three different measurement scales. First, tests are simulated in a large number of geological fracture network realizations, and the acceptable fracture transmissivity distribution parameters that produce the observed statistics of the two smallest measurement scales, i.e., 2‐m and 10‐m scales, are defined. Instead of a single value, a range of acceptable parameter values can be found to produce the observed result. Second, upscaling simulations are carried out with the calibrated networks. These indicate that the investigated system cannot be properly modeled by means of a continuum tensor presentation but would better be represented by means of “equivalent fracture” statistics. Third, the conductive characteristics of the calibrated 30‐m network blocks are compared to well test results from the same scale. The results from this preliminary analysis indicate that one‐dimensional borehole observations interpreted with standard continuum‐based methods may considerably underestimate the three‐dimensional conductive characteristics of heterogeneous, noncontinuum fractured media.
Acetaminophen inhibits neuronal inflammation and protects neurons from oxidative stress (2009)

These data show that acetaminophen has anti-oxidant and anti-inflammatory effects on neurons and suggest a heretofore unappreciated therapeutic potential for this drug in neurodegenerative diseases such as AD that are characterized by oxidant and inflammatory stress.
High Expression of Macrophage Colony-Stimulating Factor in Peritumoral Liver Tissue Is Associated With Poor Survival After Curative Resection of Hepatocellular Carcinoma (2008)

High peritumoral M-CSF and M Phi were associated with HCC progression, disease recurrence, and poor survival after hepatectomy, highlighting the importance of peritumoral tissue in the recurrence and metastasis of HCC. M-CSF and M Phi may be targets of postoperative adjuvant therapy.
Content Sharing for Mobile Devices (2008)

The miniaturisation of computing devices has seen computing devices become increasingly pervasive in society. With this increased pervasiveness, the technologies of small computing devices have also improved. Mobile devices are now capable of capturing various forms of multimedia and able to communicate wirelessly using increasing numbers of communication techniques. The owners and creators of local content are motivated to share this content in ever increasing volume; the conclusion has been that social networks sites are seeing a revolution in the sharing of information between communities of people. As load on centralised systems increases, we present a novel decentralised peer-to-peer approach dubbed the Market Contact Protocol (MCP) to achieve cost effective, scalable and efficient content sharing using opportunistic networking (pocket switched networking), incentive, context-awareness, social contact and mobile devices. Within the report we describe how the MCP is simulated with a superimposed geographic framework on top of the JiST (Java in Simulation Time) framework to evaluate and measure its capability to share content between massively mobile peers. The MCP is shown in conclusion to be a powerful means by which to share content in a massively mobile ad-hoc environment.
Association between hepatitis C virus infection and development of posttransplantation diabetes mellitus in renal transplant recipients12 (2002)

Background. Posttransplantation diabetes mellitus (PTDM) is a metabolic complication of renal transplantation. A high prevalence of DM has been recently reported in patients with chronic hepatitis C virus (HCV) infection in the nontransplant population. The aim of this study was to investigate possible factors that may have a role in the development of DM, including HCV infection in renal transplant recipients. Patients and Methods. This case-control study included 43 patients with PTDM (36 men, 7 women; mean age, 44±10 years) and 43 consecutive transplant patients who did not develop PTDM (30 men, 13 women; mean age, 37±11 years). Age, body mass index, high-dose steroid use, family history for DM and HCV, and presence of HLA-DR2, -DR3, and -DR4 were considered as possible factors for predicting PTDM. Results. Patients with PTDM were older (P =0.002) and had a higher prevalence of family history of DM (61% vs. 9%, P <0.001) and a higher rate of HCV seropositivity (72% vs. 37%, P =0.002; odds ratio = 1.94; 95% confidence interval = 1.26–2.98). The prevalence of pancreatic autoantibodies (anti-glutamic acid decarboxylase, islet cell antibody) was similar between patients with and without PTDM. In logistic regression analysis (r2 = 0.61, P <0.001), age, family history, and HCV infection were independent variables for predicting development of PTDM. Conclusion. HCV infection was associated with the development of PTDM, in addition to family history and increased age. The rate of autoantibodies against pancreatic cells was not increased in patients with HCV, which suggested that nonimmunologic mechanisms were likely to have a role in the pathogenesis of PTDM.
Circulating Blood Volume Measured by Pulse Dye-Densitometry  (1998)

This newly developed, less invasive method can measure CBV with an imprecision of 3.99+/-10.54%, 0.259+/-0.593 l (nose probe), and thus is also as accurate as the conventional radioisotope method.
Auditable Protocols for Fair Payment and Physical Asset Delivery Based on Smart Contracts (2019)

With the rapid development of electronic information technology, online transaction will gradually surpass traditional market transaction, among which online payment and asset delivery become the focus of attention. But in fact, due to the incomplete third-party payment mechanism and the intrusion risk of various charging Trojan, it is easy to cause a trust crisis. The existing centralized framework often leads to information asymmetry between the two parties. Therefore, how to realize the fairness of payment and the auditability of assets in the distributed system is a challenging problem. The emerging blockchain technology provides a new method with its openness, transparency and verifiability. Existing researches do not provide a complete shopping model for consumers, most of which focuses on payments or only on asset delivery. In this paper, we propose an auditable fair payment and physical asset delivery protocol based on smart contracts. Three types of smart contracts are designed to achieve reliable and fair payment among merchants, consumers and logistics companies. The traceability and auditability of blockchain provide an effective method to audit assets and data sharing in the whole transportation. In view of the phenomenon of goods being switched, the way of ”pre-verification” is added. In order to prevent the illegal elements to fake pickup code, induce consumers to conduct illegal operations, cause property loss, in our system the pickup codes are generated by consumers to reduce the risk of fraud. In addition, our plan designs a complete return process for the first time, providing better service experience and higher efficiency for consumers. Finally, all the contracts involved in the scheme are implemented and deployed on the ethereum test network. The results of security analysis and evaluation showed that our scheme was improved in cost, with high security and availability.
A BIAS‐CORRECTING PROCEDURE FOR BETA ESTIMATION IN THE PRESENCE OF THIN TRADING (1989)

Abstract In this paper, an alternative technique is developed for obtaining consistent estimates of beta in the presence of thin trading. The new estimator is tested on simulated data and the results are compared with those obtained from the Dimson [ 4 ] Scholes and Williams [ 9 ] techniques. The new estimator is found to have approximately the same bias as the others, but it has a considerably lower variance.
Evaluation of Disease Surveillance System for early detection of Acute Diarrhoeal Disease in Karnataka-India (2015)

Background: Evaluation of integrated disease surveillance system in Acute Diarrhoeal Diseases (ADD) in Karnataka was carried out during (Please mention duration). The specific objectives of the evaluation were to describe the structure and to evaluate the attributes of system for surveillance of ADD.
<b>The 3′ untranslated region of a rice α‐amylase gene mediates sugar‐dependent abundance of mRNA</b> (1998)

A decrease in transcript stability is one of the important mechanisms that control the sugar repression of alpha-amylase gene expression in rice suspension cells. In this study, we investigated the function of the 3' untranslated region (3'UTR) of a rice alpha-amylase gene, alpha Amy3, in relation to sugar-dependent accumulation of mRNA. By examining the transient expression of chimeric genes in rice protoplasts, we were able to demonstrate that the alpha Amy3 3'UTR mediated the sugar-dependent repression of fused heterologous gene expression. The same kinetics of accumulation of alpha Amy3 mRNA and reporter mRNA carrying the alpha Amy3 3'UTR in response to glucose deprivation were observed, suggesting that the alpha Amy3 3'UTR is sufficient, and probably the major determinant for controlling the abundance of these transcripts. Functional analysis of two subdomains of alpha Amy3 3'UTR by insertion into a sugar-inducible chimeric gene confirmed their roles in sugar repressibility. The regulatory sequences in the alpha Amy3 3'UTR may act as potent determinants of mRNA stability in response to sugar availability. This finding has important implications for studying the regulatory mechanism of sugar repression in eukaryotes.
First results on genetic variability in an autochthonous population of Roe deer from a Mediterranean forest in southern Spain (2012)

International audience
Adenovirus endocytosis (2004)

Pathogen entry into cells occurs by direct penetration of the plasma membrane, clathrin-mediated endocytosis, caveolar endocytosis, pinocytosis or macropinocytosis. For a particular agent, the infectious pathways are typically restricted, reflecting a tight relationship with the host. Here, we survey the uptake process of human adenovirus (Ad) type 2 and 5 and integrate it into the cell biology of endocytosis. Ad2 and Ad5 naturally infect respiratory epithelial cells. They bind to a primary receptor, the coxsackie virus B Ad receptor (CAR). The CAR-docked particles activate integrin coreceptors and this triggers a variety of cell responses, including endocytosis. Ad2/Ad5 endocytosis is clathrin-mediated and involves the large GTPase dynamin and the adaptor protein 2. A second endocytic process is induced simultaneously with viral uptake, macropinocytosis. Together, these pathways are associated with viral infection. Macropinocytosis requires integrins, F-actin, protein kinase C and small G-proteins of the Rho family, but not dynamin. Macropinocytosis per se is not required for viral uptake into epithelial cells, but it appears to be a productive entry pathway of Ad artificially targeted to the high-affinity Fcgamma receptor CD64 of hematopoietic cells lacking CAR. In epithelial and hematopoietic cells, the macropinosomal contents are released to the cytosol. This requires viral signalling from the surface and coincides with particle escape from endosomes and infection. It emerges that incoming Ad2 and Ad5 distinctly modulate the endocytic trafficking and disrupt selective cellular compartments. These features can be exploited for effective artificial targeting of Ad vectors to cell types of interest.
The Times in Which We Live (1985)

The Times in Which We Live Get access Carol H Meyer Carol H Meyer Editor-in-Chief Search for other works by this author on: Oxford Academic PubMed Google Scholar Social Work, Volume 30, Issue 3, May-June 1985, Page 195, https://doi.org/10.1093/sw/30.3.195 Published: 01 May 1985
Functional Characterization of Muscarinic Receptors in Human Schwann Cells (2020)

Functional characterization of muscarinic cholinergic receptors in myelinating glial cells has been well described both in central and peripheral nervous system. Rat Schwann cells (SCs) express different muscarinic receptor subtypes with the prevalence of the M2 subtype. The selective stimulation of this receptor subtype inhibits SC proliferation, improving their differentiation towards myelinating phenotype. In this work, we describe for the first time that human SCs are cholinoceptive as they express several muscarinic receptor subtypes and, as for rat SCs, M2 receptor is one of the most abundant. Human SCs, isolated from adult nerves, were cultured in vitro and stimulated with M2 muscarinic agonist arecaidine propargyl ester (APE). Similarly to that observed in rat, M2 receptor activation causes a decreased cell proliferation and promotes SC differentiation as suggested by increased Egr2 expression with an improved spindle-like shape cell morphology. Conversely, the non-selective stimulation of muscarinic receptors appears to promote cell proliferation with a reduction of SC average cell diameter. The data obtained demonstrate that human SCs are cholinoceptive and that human cultured SCs may represent an interesting tool to understand their physiology and increase the knowledge on how the cholinergic stimulation may contribute to address human SC development in normal and pathological conditions.