gebhart/patrepeval huggingface dataset:
Effects of blow molding ratio on mechanical properties of polylactide nanocomposite films (2010)

The results of the investigations of the effect of blow-up ratio of nanocomposite poly(lactic acid) (PLA) films on the mechanical properties determined under static tension are discussed. Investigated films contain additives in the form of a montmorillonite (MMT) nanofiller (LC sample) or MMT and poly(methyl methacrylate) (PMMA) as a modifier (LCM sample) or MMT and poly(ethylene glycol) (PEG) as a plasticizer (LCG sample). Using the X-ray diffraction (XRD) method, it was found that the screw shape of the co-rotating twin-screw extruder, applied to prepare a granulated nanocomposite, significantly influenced the dispersion of MMT within the PLA matrix. The PLA film containing the additives and subjected to a proper extrusion blow molding have better mechanical properties as compared to those of a neat PLA (L sample) film. These properties were found to be the best when the blow-up ratio (R) of the nanocomposite films was equal to 4. The images obtained by means of the transmission electron microscopy (TEM) confirmed that ordering of the MMT platelets within the PLA matrix occurred during the film blowing, which induced an improvement in the film mechanical properties. The presented results prove usefulness of the extrusion blow molding as a method of manufacturing nanocomposite films based on the PLA matrix.
Longitudinal study of blood pressure and white matter hyperintensities (2001)

Hypertension is a major risk factor for severe WMH. Subjects taking antihypertensive drugs and who have controlled blood pressure had a reduced risk of severe WMH. Longitudinal studies are needed to investigate whether reduction of the development of WMH, by treatment and prevention of hypertension, might reduce the subsequent risk of cognitive deterioration or stroke.
Hepatic farnesyl diphosphate synthase expression is suppressed by polyunsaturated fatty acids (2005)

Dietary vegetable oils and fish oils rich in PUFA (polyunsaturated fatty acids) exert hypocholesterolaemic and hypotriglyceridaemic effects in rodents. The plasma cholesterol-lowering properties of PUFA are due partly to a diminution of cholesterol synthesis and of the activity of the rate-limiting enzyme HMG-CoA reductase (3-hydroxy-3-methylglutaryl-CoA reductase). To better understand the mechanisms involved, we examined how tuna fish oil and individual n-3 and n-6 PUFA affect the expression of hepatic FPP synthase (farnesyl diphosphate synthase), a SREBP (sterol regulatory element-binding protein) target enzyme that is subject to negative-feedback regulation by sterols, in co-ordination with HMG-CoA reductase. Feeding mice on a tuna fish oil diet for 2 weeks decreased serum cholesterol and triacylglycerol levels, by 50% and 60% respectively. Hepatic levels of FPP synthase and HMG-CoA reductase mRNAs were also decreased, by 70% and 40% respectively. Individual n-3 and n-6 PUFA lowered FPP synthase and HMG-CoA reductase mRNA levels in H4IIEC3 rat hepatoma cells to a greater extent than did stearate and oleate, with the largest inhibitory effects occurring with arachidonate, EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid). We observed a similar inhibitory effect on protein levels of FPP synthase. The suppressive effect of PUFA on the FPP synthase mRNA level was not due to a decrease in mRNA stability, but to transcription inhibition. Moreover, a lower nuclear availability of both SREBP-1 and SREBP-2 mature forms was observed in HepG2 human hepatoblastoma cells treated with arachidonate, EPA or DHA. Taken together, these data suggest that PUFA can down-regulate hepatic cholesterol synthesis through inhibition of HMG-CoA reductase and FPP synthase, at least in part through impairment of the SREBP pathway.
Potassium ferricyanide: a stabilizer for horseradish peroxidase. (1984)

Sodium nitroprusside has been used as a stabilizing agent for HRP histochemistry since 1919. However, it is known to have toxic effects orally, intravenously, and subcutaneously. In order to avoid the use of sodium nitroprusside as a stabilizer in HRP histochemistry, we have tested other chemically related compounds to stabilize the reaction product equally well. We will show that potassium ferricyanide is an excellent stabilizer of the chromogen reaction product. In addition, the reaction product remains stable without noticeable changes over a period of several months. As it is far less toxic than sodium nitroprusside, it should be the stabilizer of choice, especially in those laboratories where the histochemical HRP reaction is used frequently.
Performance evolution blueprint: Understanding the impact of software evolution on performance (2013)

Understanding the root of a performance drop or improvement requires analyzing different program executions at a fine grain level. Such an analysis involves dedicated profiling and representation techniques. JProfiler and YourKit, two recognized code profilers fail, on both providing adequate metrics and visual representations, conveying a false sense of the performance variation root. We propose performance evolution blueprint, a visual support to precisely compare multiple software executions. Our blueprint is offered by Rizel, a code profiler to efficiently explore performance of a set of benchmarks against multiple software revisions.
A similarity-based approach for test case prioritization using historical failure data (2015)

Test case prioritization is a crucial element in software quality assurance in practice, specially, in the context of regression testing. Typically, test cases are prioritized in a way that they detect the potential faults earlier. The effectiveness of test cases, in terms of fault detection, is estimated using quality metrics, such as code coverage, size, and historical fault detection. Prior studies have shown that previously failing test cases are highly likely to fail again in the next releases, therefore, they are highly ranked, while prioritizing. However, in practice, a failing test case may not be exactly the same as a previously failed test case, but quite similar, e.g., when the new failing test is a slightly modified version of an old failing one to catch an undetected fault. In this paper, we define a class of metrics that estimate the test cases quality using their similarity to the previously failing test cases. We have conducted several experiments with five real world open source software systems, with real faults, to evaluate the effectiveness of these quality metrics. The results of our study show that our proposed similarity-based quality measure is significantly more effective for prioritizing test cases compared to existing test case quality measures.
Soft-Ground Aircraft Arresting Systems. (1987)

Abstract : The soft-ground aircraft arresting system study was initiated to determine whether or not aircraft having gross weight of 114,000 pounds to 630,000 pounds could be safely stopped after overrunning the available length of runway. The extended length of runway was limited to 1000 feet and the maximum velocity of the overrunning aircraft was selected to be 70 knots. The system was to be completely passive, have a long life, and easily repaired and maintained. Several arrestor materials such as clay, sand, gravel, water, an plastic foam were considered. An aircraft wheel/arrestor material model was developed and incorporated into a computer program FITER which allowed the determination of the aircraft stopping distance, landing gear loads, dynamic response, and rut depth in the arrestor material. Analyses conducted showed that sand, clay and water systems were not suitable arresting materials. Aircraft arrestment simulations were conducted for gravel and plastic foam arrestors and it was found that all aircraft could be safely stopped in less than 1000 feet. Evaluation of the stopping distance in an arrestor bed with the stopping distance of an extended runway was made and it was found that the arrestor system was needed to assure the safe stopping of an aircraft. Initial arrestor bed configurations were developed along with installation methods and attachment of the arrestor to the extended runway surface. Keywords: Aircraft arrestor, Foam arrestor, Soft-ground arrestor, Aircraft decelerator.
Commercial compact cyclotrons in the 90`s (1995)

Cyclotrons continue to be efficient accelerators for radio-isotope production. In recent years, developments in the accelerator technology have greatly increased the practical beam current in these machines while also improving the overall system reliability. These developments combined with the development of new isotopes for medicine and industry, and a retiring of older machines indicate a strong future for commercial cyclotrons. In this paper the authors will survey recent developments in the areas of cyclotron technology, as they relate to the new generation of commercial cyclotrons. Design criteria for the different types of commercial cyclotrons will be presented, with reference to those demands that differ from those in a research oriented cyclotron project. The authors also discuss the possibility of systems designed for higher energies and capable of extracted beam currents of up to 2.0 mA.
Mastering Windows XP Home Edition (2001)

From the Publisher:
Written completely from scratch, Mastering Windows XP Home Edition is the best choice for anyone using Microsoft's latest consumer operating system. 
This comprehensive guide covers all of the newest features including the revamped desktop, Backup and Recovery Tools, Device Driver Rollback, CD Burning, faxing and digital media features. The CD includes scores of handy utilities and applications. 
Once readers have the basics down, they'll master more advanced tasks, making this book a one-stop shop for all Windows XP home users.
On the CD
A fully searchable electronic copy of the book plus valuable Windows utilities, including e-book software; MP3 ripping, encoding, and playing tools; and evaluation versions of DVD players, image-manipulation software, compression utilities, Internet-security software, and more.
The structure of pig and sheep insulins (1955)

Research Article| August 01 1955 The structure of pig and sheep insulins H. Brown; H. Brown 1Biochemical Laboratory, University of Cambridge Search for other works by this author on: This Site PubMed Google Scholar F. Sanger; F. Sanger † 1Biochemical Laboratory, University of Cambridge Search for other works by this author on: This Site PubMed Google Scholar Ruth Kitai Ruth Kitai 1Biochemical Laboratory, University of Cambridge Search for other works by this author on: This Site PubMed Google Scholar Biochem J (1955) 60 (4): 556–565. https://doi.org/10.1042/bj0600556 Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share MailTo Twitter LinkedIn Cite Icon Cite Get Permissions Citation H. Brown, F. Sanger, Ruth Kitai; The structure of pig and sheep insulins. Biochem J 1 August 1955; 60 (4): 556–565. doi: https://doi.org/10.1042/bj0600556 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsBiochemical Journal Search Advanced Search This content is only available as a PDF. © 1955 CAMBRIDGE UNIVERSITY PRESS1955 Article PDF first page preview Close Modal You do not currently have access to this content.
FETAL ELECTROENCEPHALOGRAPHY USING A NEW, FLEXIBLE ELECTRODE (1981)

A single flexible active electrode for monitoring the fetal electroencephalogram (FEEG), has been designed specifically for use in routine obstetrics. It does not require penetration of or adherence to the fetal scalp, and it is reusable. The equipment's performance has been tested in 20 normal labours. The recordings obtained were not contaminated by the fetal electrocardiogram and were relatively free from artefact so that minimal filtering of the signal was required. No FEEG signal was obtained if the electrode was applied to breech presentations. The trace obtained from a healthy fetus was comparable with that recorded after delivery.
A pilot study of oral calcitriol (1,25-dihydroxyvitamin D3) for relapsing-remitting multiple sclerosis (2005)

Oral calcitriol is safe and well tolerated for up to one year by diet compliant relapsing-remitting MS patients. Further study of vitamin D related mechanisms is warranted in MS.
Towards built-in-self-test for SNR testing of a mixed-signal IC (2002)

Built-in-self-test (BIST) for digital systems has become feasible for a variety of digital VLSI systems. However, mixed analog-digital BIST (MADBIST) has not yet achieved the same degree of practicality. An accurate analog signal source, as well as circuitry to measure the analog response, must be fabricated onto the chip, and must be self-calibrating. A MADBIST is discussed which could be used for a signal-to-noise ratio test on a chip which includes a digital-to-analog converter, an analog-to-digital converter, and a microprocessor which includes RAM and ROM. The MADBIST strategy for the SNR test is introduced, accuracy issues are discussed, and simulation results are presented.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Training and evaluation of a knowledge-based model for automated treatment planning of multiple brain metastases (2019)

The Journal of Cancer Metastasis and Treatment is an open access journal focused on cancer metastasis and treatment, including the occurrence, development, progression, metastasis, and treatment of oncologic disease. It covers basic, translational and clinical research related to cancer cell biology, genomics, precision medicine, oncology internal medicine, radiotherapy and radiology, obstetrics and gynecology, pediatrics, surgery, hematology, neurooncology, etc.
A 5-Year Survey of Applications and Results of Placing Solid Chemical Inhibitors in the Formation via Hydraulic Fracturing (2010)

Abstract Solid chemical inhibitors placed in the formation during hydraulic fracturing have provided inhibition protection for up to five years. Deepwater operators, especially, desire longer inhibition periods. This paper provides a summary on treatment results over five years and over 1500 wells. It covers inhibition for scale, paraffin and asphaltene either as a single application or as a multiple product application. These applications have been in various formations including deepwater, tight gas and coal bed methane formations. The longest documented treatment has been in the ground for over five years. Placing a solid chemical inhibitor into the formation via the fracturing process requires a product that is compatible with the fracturing fluid, does not adversely affect conductivity and provides long term inhibition through the controlled release of the inhibitor into the produced fluid. The solid inhibitor is added to the fracturing proppant. Primarily this is a mass-balance process by which a finite amount of inhibitor desorbs over time. The goal is to maximize the inhibitor loading, minimize the chemical release rate without negatively impacting the stimulation. In the treated wells inorganic and organic deposition has been arrested for extended periods when compared to alternative liquid addition applications. Solid scale inhibitors have been the most common treatment and are monitored through residual analysis. The paraffin and asphaltene inhibitors are monitored through comparative testing. The paper details both the time and the cumulative production that has flowed through the respective proppant packs. Wells that are scheduled for hydraulic fracturing and that display tendencies for organic and/or inorganic deposition are candidates for solid chemical placement during the fracture. The results from over 1500 wells indicate that this method for deposition inhibition reduces intervention costs and lowers lifting costs.
Genetic Association Between a Lymphoid Tyrosine Phosphatase (<i>PTPN22</i>) and Type 1 Diabetes (2005)

The lymphoid-specific phosphatase (LYP) encoded by PTPN22 is involved in preventing spontaneous T-cell activation by dephosphorylating and inactivating T-cell receptor-associated Csk kinase. We have genotyped 396 type 1 diabetic patients and 1,178 control subjects of Caucasian descent from north central Florida and report a strong association between type 1 diabetes and a polymorphism (R620W) in the PTPN22 gene. The homozygous genotype for the T allele encoding the 620W residue is associated with an increased risk for developing type 1 diabetes (odds ratio [OR] = 3.4, P < 0.008), and the heterozygous genotype C/T had an OR of 1.7 (P = 6 x 10(-6)). The C/C homozygous genotype is protective against type 1 diabetes (OR = 0.5, P = 6 x 10(-6)). Furthermore, transmission disequilibrium analysis of 410 affected sibpair and simplex families of Caucasian descent indicated that the type 1 diabetes-associated T allele is transmitted more often (57.2%) than randomly expected (P < 0.003). Together with previous reports of the association between PTPN22 and type 1 diabetes, as well as rheumatoid arthritis and systemic lupus erythematosus, these results provide compelling evidence that LYP is a critical player in multiple autoimmune disorders.
Recovery of bio-based butanol (2012)

Product recovery is crucial for fermentative butanol production. Bio-based fermentative butanol production systems benefit from answering the question to what extent, and in which form, integration between fermentation and product recovery should be applied. The product recovery is applied in order to minimize the impact of butanol inhibiting during fermentation. This thesis addresses the product recovery methods applicable to butanol recovery. Two techniques are investigated in more detail, namely liquid demixing based-recovery and adsorptive-recovery. This work further provides a basis for process optimization for integrated product recovery and finally determines the economic potential of butanol production systems.
Pattern recognition using neural networks that learn from fuzzy rules (2002)

Clustering methods have been used extensively in computer vision and pattern recognition. Fuzzy clustering has been shown to be advantageous over crisp (or traditional) clustering in that total commitment of a vector to a given class is not required in each iteration. Recently fuzzy clustering methods have shown spectacular ability to detect not only volume clusters, but also clusters which are actually "thin shells", i.e. curves and surfaces. Most analytic fuzzy clustering approaches are derived from the fuzzy C means (FCM) algorithm. The FCM uses the probabilistic constraint that the membership of a data point across classes sum to 1. The memberships resulting from FCM and its derivatives, however, do not always correspond to the intuitive concept of degree of belonging or compatibility. Moreover, the algorithms have trouble in noisy environments. In this paper, we cast the clustering problem into framework of possibility theory. In this paper we introduce a comparative study between clustering using unsupervised learning and possibilistic clustering approach.
Optimization Results of High Strength Steel Production Process (2007)

This DOI is not currently attached to any metadata records. DOIs can’t actually ever be deleted (they’re persistent), but sometimes our members create DOIs in error. We do have a process to approximate deletion which we follow only in rare cases where the DOI has been genuinely created in error, and most crucially, if the DOI has never been published anywhere online or in print and never otherwise distributed to or communicated with anyone (authors, readers, reviewers, etc.
A Rapid and Simple Method for the Determination of Esterified Fatty Acids and for Total Fatty Acids in Blood (1953)

Carboxylic acid esters react with hydroxylamine in alkaline solution to form hydroxamic acids.These acids produce a red to violet reaction with ferric chloride which has been utilized by Feigl (1949) for the microchemical detection of carboxylic acid derivatives.Lipmann and Tuttle (1945) developed a method for the quantitative assay of acylphosphates by allowing hydroxyl- amine to react with these substances in aqueous solutions at pH 6.0.Hestrin (1949) adapted the reaction for the estimation of short-chain esters by employing alkaline aqueous reagents.Under these conditions esters of higher fatty acids did not react.In order to achieve a reaction of neutral fats and other natural lipids with these reagents, Bauer and Hirsch (1949) employed strictly an- hydrous conditions and developed a method for the determination of the total esterified fatty acids in blood serum.Since almost all the fatty acids in blood serum are in esterified form, this method gives results identical with those testing total fatty
A 12-pass laser amplifier scheme for achieving efficient high gain amplification (2000)

Summary form only given.If one wishes to extract energy from an amplifier one usually requires substantial input energies, and the net gain is modest. Gain and energy extraction can be improved by double passing an amplifier system, often using nonlinear optical phase conjugation to compensate for aberrations. In amplifier systems it is often convenient to use relay imaging, using an intermediate telescope. In this paper we introduce an optical element to intercept beams propagating in a self-imaging system and introduce an angle multiplexing arrangement. This makes it possible to pass a beam through an amplifier many times. The technique is generic and applicable to a variety of laser amplifiers.
A Convergent Total Synthesis of the Multidrug Resistance-Reversing Agent Hapalosin (1995)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTA Convergent Total Synthesis of the Multidrug Resistance-Reversing Agent HapalosinTam Q. Dinh and Robert W. ArmstrongCite this: J. Org. Chem. 1995, 60, 25, 8118–8119Publication Date (Print):December 1, 1995Publication History Published online1 May 2002Published inissue 1 December 1995https://pubs.acs.org/doi/10.1021/jo00130a001https://doi.org/10.1021/jo00130a001research-articleACS PublicationsRequest reuse permissionsArticle Views644Altmetric-Citations32LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (2)»Supporting Information Supporting Information Get e-Alerts