gebhart/patrepeval huggingface dataset:
Regulation of transglutaminase type II by transforming growth factor-beta 1 in normal and transformed human epidermal keratinocytes. (1990)

This study examines the effect of transforming growth factor-beta 1 (TGF-beta 1) on the expression of Type I and II transglutaminase in normal human epidermal keratinocytes (NHEK cells). Treatment of undifferentiated NHEK cells with 100 pM TGF-beta 1 caused a 10- to 15-fold increase in the activity of a soluble transglutaminase. Based on its cellular distribution and immunoreactivity this transglutaminase was identified as Type II (tissue) transglutaminase. TGF-beta 1 did not enhance the levels of the membrane-bound Type I (epidermal) transglutaminase activity which is induced during squamous cell differentiation and did not increase Type II transglutaminase activity in differentiated NHEK cells. Several SV40 large T antigen-immortalized NHEK cell lines also exhibited a dramatic increase in transglutaminase Type II activity after TGF-beta 1 treatment; however, TGF-beta 1 did not induce any significant change in transglutaminase activity in the carcinoma-derived cell lines SCC-13, SCC-15, and SQCC/Y1. Half-maximal stimulation of transglutaminase Type II activity in NHEK cells occurred at a dose of 15 pM TGF-beta 1. TGF-beta 2 was about equally effective. This enhancement in transglutaminase activity was related to an increase in the amount of transglutaminase Type II protein as indicated by immunoblot analysis. Northern blot analyses using a specific cDNA probe for Type II transglutaminase showed that exposure of NHEK cells to TGF-beta 1 caused a marked increase in the mRNA levels of this enzyme which could be observed as early as 4 h after the addition of TGF-beta 1. Maximal induction of transglutaminase Type II mRNA occurred between 18 and 24 h. The increase in Type II transglutaminase mRNA levels was blocked by the presence of cycloheximide, suggesting that this increase in mRNA by TGF-beta 1 is dependent on protein synthesis.
Relationship between the photo-induced degradation characteristics and film structure of a-Si:H films prepared under various conditions (2002)

We have investigated the photo-induced degradation characteristics of high growth-rate (/spl sim/20 /spl Aring//s) a-Si:H films prepared under various conditions and find that the stability of the film is closely related to the Si-H/sub 2/ bond density in the film. The results obtained by the Schottky cell measurements indicate that highly stable films with low Si-H/sub 2/ bond density are obtained at moderately high temperatures of around 350/spl deg/C. As our first trial, we made a small number of nip solar cells at high growth-rate (/spl sim/20 A/s) and confirmed the consistency between the result of the Schottky cell behavior and the solar cell performance. The best performance cell we have obtained so far exhibits a 9.3% initial efficiency, with a stabilized efficiency of 7.4% after a 500 h, AM1.5, 100 mW/cm/sup 2/ light exposure.
Three‐dimensional fiber architecture of the nonpregnant human uterus determined ex vivo using magnetic resonance diffusion tensor imaging (2005)

The global muscle and collagen fiber orientation in the human uterus has been analyzed hitherto by various standard microscopic techniques. However, no widely accepted model of the fiber architecture of the myometrium could be acquired. The purpose of the present study was to investigate the uterus by magnetic resonance (MR) diffusion tensor imaging (DTI) in a 3D macroscopic approach. Ex vivo MR DTI measurements were performed on five uteri from nonpregnant patients. The main diffusion directions reflecting the orientation of directional structures in the examined tissues were determined from diffusion-weighted spin-echo measurements. A fiber tracking algorithm was used to extrapolate the fiber architecture. The method was validated against histological slides and indirectly through the analysis of leiomyomas, which exhibit less anisotropy than normal myometrium. Significant anisotropy was found in most regions of all examined nonpregnant human uteri. But only two systems of fibers were found running circularly along the intramural part of the uterine tubes. They merged caudally and built a close fitting envelope of circular layers around the uterine cavity. On the cervix, circular fibers were observed in the outer part as well as mostly longitudinal fibers in the inner part. These results confirm the existence of directional structures in the complex fiber architecture of the human uterus. They also indicate that MR DTI is a beneficial and complementary tool to standard microscopic techniques to determine the intrinsic fiber architecture in human organs.
[Intraoperative radiotherapy in carcinoma of the body and tail of the pancreas]. (1997)

The prognosis for patients with carcinoma of the body and tail of the pancreas is extremely poor. We analyzed the effectiveness of intraoperative radiotherapy (IOR) from the viewpoint of the cumulative survival rate and pain relief. The prognosis of patients who underwent IOR with/without resection was significantly longer than for patients without IOR (p < 0.0001). Better pain relief was obtained by IOR. Although a randomized prospective study is required, resection and IOR will be the central treatment modalities for carcinoma of the body and tail of the pancreas.
Organic Syntheses by Means of Noble Metal Compounds. VII.<sup>1</sup> Reactions of Olefin-Palladium Chloride Complexes with Carbon Monoxide (1964)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTOrganic Syntheses by Means of Noble Metal Compounds. VII.1 Reactions of Olefin-Palladium Chloride Complexes with Carbon MonoxideJiro. Tsuji, Masanobu. Morikawa, and Jitsuo. KijiCite this: J. Am. Chem. Soc. 1964, 86, 22, 4851–4853Publication Date (Print):November 1, 1964Publication History Published online1 May 2002Published inissue 1 November 1964https://pubs.acs.org/doi/10.1021/ja01076a026https://doi.org/10.1021/ja01076a026research-articleACS PublicationsRequest reuse permissionsArticle Views408Altmetric-Citations72LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
The reverse genetics applied to fish RNA viruses (2011)

Aquaculture has expanded rapidly to become a major economic and food-producing sector worldwide these last 30 years. In parallel, viral diseases have emerged and rapidly spread from farm to farm causing enormous economic losses. The most problematic viruses encountered in the field are mainly, but not exclusively, RNA viruses belonging to the Novirhabdovirus, Aquabirnavirus, Alphavirus and Betanodavirus genera. The recent establishment of reverse genetics systems to recover infectious fish RNA viruses entirely from cDNA has made possible to genetically manipulate the viral genome. These systems have provided powerful tools to study all aspects of the virus biology and virus-host interactions but also gave the opportunity to use these viruses as live vaccines or as gene vectors. This review provides an overview on the recent breakthroughs achieved by using these reverse genetics systems in terms of viral protein function, virulence and host-specificity factor, vaccine development and vector design.
Random pulse width modulation techniques for converter-fed drive systems-a review (1994)

Random pulse width modulation (RPWM) techniques for voltage-controlled power electronic converters have been attracting an increasing interest due to the unique effects of these techniques on the converter-supplied drive systems. A number of RPWM strategies have been reported and a beneficial impact on the acoustic noise and vibration has been unanimously agreed upon. The paper presents a synthetic review of the state of the art in the RPWM theory and practice. Topics covered include principles of RPWM, means of randomization, review of the existing RPWM techniques, power spectra, implementation issues, and documented effects of RPWM on electric drive systems.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Unfused C2C12 Mouse Skeletal Muscle Cells Express Neurofilament 140K Protein. (1997)

Expression of neurofilament 140K protein in C2C12 mouse skeletal muscle cells was studied. Immunofluorescence and immunoblot analyses revealed that NF140K was expressed at the proliferative stage and was colocalized with the muscle-specific intermediate protein desmin. As muscle cell differentiation proceeded, the number of NF140K-positive cells decreased whereas the number of cells expressing muscle-specific marker proteins such as sarcomeric myosin heavy chain and troponin-T increased. Down-regulation of NF140K and upregulation of a myogenic regulatory gene, the myogenin gene, started simultaneously. In differentiated muscle cell cultures, unfused cells residing between myotubes remained NF140K-positive. NF140K and desmin double-positive cells were also found in a primary culture of adult mouse skeletal muscle cells. The results suggest that NF140K may be a unique marker for uncommitted myoblasts.
Amperometric sensor for choline and acetylcholine based on a platinum electrode modified by a co-crosslinked bienzymic system (1995)

A fast-response and sensitive amperometric biosensor for choline and acetylcholine based on choline oxidase and acetylcholinesterase immobilized on a platinum electrode by co-crosslinking with bovine serum albumin and glutaraldehyde has been developed. The immobilization procedure proved fast and simple, not requiring dedicated manipulation. Detection limits were in the sub-micromolar range and linearity extended over three concentration decades. After one month of discontinuous use, 70% of the initial sensitivity was still observed. The response time was around 1 s for both analytes making the developed biosensor a suitable detector for flow injection systems and high-performance liquid chromatography.
Summary session B: more observations at existing accelerators and concerns for future machines (2005)

Beginning with the International Workshop on Multibunch Instabilities in Tsukuba (KEK, 1997) [1], and continuing with special Electron Cloud workshops in Santa Fe (LANL/ANL, 2000) [2], Tsukuba (KEK, 2001) [3], Geneva (CERN, 2002) [4] and the present workshop, it is remarkable that new observations of electron cloud effects continue to be reported, spreading from proton rings to positron and electron rings to heavy-ion linacs and rings.This paper summarizes a rich collection of recent observations, as well as issues for future machines, presented in Session B. An attempt is also made to summarize conclusions and questions raised by the presenters. OUTLINEThe papers in this session can be grouped as follows:High-energy short-pulse proton rings J. M. Jimnez, "Electron cloud and vacuum effects in the SPS" T. Kroyer, "Unexpected results on microwave waveguide mode transmission measurements in the SPS beampipe"Medium/high-energy long-pulse proton rings R. Macek, "Experimental studies of electron cloud effects at the Los Alamos PSR: A status report" T. Toyama, "EC effects in the J-PARC rings and related topics" Heavy-ion rings and linacsW. Fischer, "Electron clouds and vacuum pressure rise in RHIC" A. Drees, "Correlation of pressure rise and experimental backgrounds at RHIC in Run04" A. Molvik, "Experimental studies of electron and gas sources in a heavy-ion beam" High-energy positron/electron ringsA. Novokhatski, "Experimental and simulation studies of electron cloud and multipacting in the presence of small solenoidal fields" A. Temnykh, Comments on preliminary results at CESR Short pulse vs. long pulse is a somewhat arbitrary categorization for proton rings based on the dynamics between the electron cloud and proton bunches, including the mechanism for amplification of the cloud.In a long pulse, essentially all the electrons in the chamber are trapped in the bunch potential during the bunch passage.
Bidirectional single-longitudinal mode SOA-fiber ring laser based on optical filter assisted gain starvation (2015)

Generation of a single-longitudinal mode (SLM) in bidirectional ring lasers has direct impact on the laser linewidth and dynamic range of operation, when used in rotation sensing applications. Besides, operating at a specific wavelength helps in optimizing the performance of the system components. In this work, we report a novel method for generating SLM in bidirectional SOA-fiber ring laser using mechanically tunable Fabry-Perot filter with 1-nm bandwidth. The method is based on gain starvation by tuning the central wavelength of the filter in the blue edge of the gain-wavelength response. By adjusting the SOA driving current, the oscillation condition is satisfied mainly for single mode and bidirectional operation can be achieved simultaneously. The SLM operation is verified by monitoring the beating signal between the modes on an RF spectrum analyzer. Using an SOA with a small-signal gain of 20 dB at 300 mA pumping current and a gain bandwidth of 100 nm centered around 1490 nm; the central wavelength of the ring laser could be tuned from 1440 nm to 1480 nm with a side-mode suppression ratio of 25 dB.
Validity of target area identified with Xe-133 single photon emission computed tomography for lung volume reduction surgery in patients with non-bullous emphysema. (1998)

非嚢胞性肺気腫に対する肺容量減少術におけるXeガス洗い出しSPECT (single-photon emissioncomputed tomography) を利用した, 切除部位と切除範囲の決定が妥当であるか否かを, 10例の非瘻胞性肺気腫患者を対象に検討した.XeSPECT洗い出し3分相でも残気の見られる部位をWO3として, 肺容量減少術におけるtarget areaとした.FEV1.0術前646±50mL/secから術後763±68mL/sec (p=.029), 動脈血酸素分圧は術前71.4±3.7mrnHgから術後77, 8±2.6mmHg (p=.069), 6分間歩行距離も術前293±44mから術後359±51m (p=.013) と, それぞれ改善した.Xeガス洗い出しSPECTに基づき決定されたWO3はtargetareaとして妥当であることが示された.
Brennraumdruckbasierte Extremwertregelung für direkteinspritzende OttomotorenSelf-Tuning Extremum Control Based on Cylinder Pressure Sensors for Direct Injection Spark Ignition Engines (2009)

Zusammenfassung Es wird eine brennraumdruckbasierte Extremwert-Regelung zur Online-Optimierung der Verbrennungsschwerpunktlage bzw. des Zündwinkels hinsichtlich maximaler Drehmomentabgabe bzw. maximalem indiziertem Mitteldruck vorgestellt. Die Regelung hält zylinder-individuell — unabhängig von Fertigungstoleranzen, Alterung und Sensorfehlern — den für den jeweiligen Motorbetriebspunkt optimalen Wert von Zündzeitpunkt bzw. Verbrennungsschwerpunktlage und regelt diese unabhängig von Störungen.
Intestine and Innate Immunity (2009)

While the intestinal immune system coexists[DPM1] with commensal bacterial flora through immunological tolerance, invading microorganisms are recognized and properly eliminated. However, it remains unknown what kinds of cells in the intestine initiate immune responses and how they activate host immunity. Recently, we identified a subset of CD11chiCD11bhi lamina propria (LP) dendritic cells (DCs) as TLR5-expressing cells, which have the ability to activate adaptive immune responses. The LPDCs induced antigen-specific Th17 cells as well as Th1 cells in a TLR5-dependent manner. In addition, they acted on naïve B cells to induce their development to immunoglobulin A (IgA)+ plasma cells in response to flagellin, and such IgA+ plasma cell generation took place in a gut-associated lymphoid tissue (GALT)-independent fashion. Our findings demonstrate unique properties of LPDCs and the importance of TLR5 for adaptive immunity in the intestine. We also generated and examined mutant mice of ATG16L1. ATG16L1 is a component of autophagy machinery and has been reported to be a candidate gene responsible for susceptibility to Crohn's disease. We discuss a novel role for autophagy in the regulation of the inflammatory immune responses in the intestine.
Bandlets for HDTV Video Processing (2008)

This DOI is not currently attached to any metadata records. DOIs can’t actually ever be deleted (they’re persistent), but sometimes our members create DOIs in error. We do have a process to approximate deletion which we follow only in rare cases where the DOI has been genuinely created in error, and most crucially, if the DOI has never been published anywhere online or in print and never otherwise distributed to or communicated with anyone (authors, readers, reviewers, etc.
Homogeneous catalysed hydrogenation of HMF (2018)

Homogeneous Ru-catalyzed hydrogenation of HMF delivers a high percentage of <italic>trans</italic>-THFDM rather than only <italic>cis</italic>-THFDM known from heterogeneous hydrogenation.
Direct Observations of Cracks and Voids in Structural Materials by X-ray Imaging Using Ultra-bright Synchrotron Radiation (2003)

Refraction contrast X-ray imaging experiments were conducted on acrylic resin with an artificial cylindrical hole, A7075 aluminum alloy, A6063 aluminum castings, mild steel with cracks or voids, and low alloy steel with inclusions, using a ultra-bright synchrotron radiation X-ray beam in BL24XU hutch C of SPring-8. Conventional absorption contrast X-ray imaging experiments were also done for the comparison. The X-ray beam was controlled to be monochromatic by Si double-crystals and collimated by a slit. The distance between the sample and the detector was changed from 0 to 3 m, and the X-ray energy was 15 to 25 keV. Photographs were taken by X-ray film and/or X-ray CCD camera. As a result, the refraction imaging method gave a much more distinct image of the artificial cylindrical hole in acrylic resin as compared with the absorption method. The fatigue cracks in aluminum alloy and mild steel were also distinctly observed. The Xray imaging revealed the presence of MnS nonmetallic inclusions in low alloy steel. Void defects in aluminum castings were clearly detected by the imaging. In addition, in-situ observation of tensile fracture of aluminum alloys using a high resolution X-ray CCD camera system was successfully conducted. The observations by use of asymmetric reflection technique for X-ray imaging experiment were also well performed. From above, the X-ray imaging method using ultra-bright synchrotron radiation is concluded to be very useful for fracture research of materials.
A novel EOS that combines van der Waals and Dieterici potentials (2005)

Abstract A novel approach is proposed for solving the problem of the overestimation of the liquid–liquid equilibrium (LLE) range in mixtures typically associated with the use of equations of state (EOS) of the van der Waals type. This approach modifies the internal EOS structure by combining the van der Waals and the Dieterici forms. It advantageously uses the drawback of the Dieterici form, which strongly underestimates the LLE range. Thus, the new EOS is capable of generating an appropriate balance for the representation of vapor–liquid equilibria (VLE) and LLE critical data and therefore represents a major improvement in comparison with typical van der Waals–type EOSs. In addition, it gives accurate representation of the Joule–Thomson inversion curve and predicts critical data for nonpolar mixtures without any binary parameters. For polar systems, the novel EOS predicts critical data for complete homologous series of mixtures using a pair of binary parameters evaluated from a single system. © 2005 American Institute of Chemical Engineers AIChE J, 2005
Quantum impurity spin in Majorana edge fermions (2010)

We show that Majorana edge modes of two-dimensional spin-triplet topological superconductors (superfluids) have Ising-type spin density whose direction is determined by the $\mathbit{d}$-vector characterizing the spin-triplet pairing symmetry. Exchange coupling between an impurity spin $(S=\frac{1}{2})$ and Majorana edge modes is thus Ising-type. Under external magnetic field perpendicular to the Ising axis, the system can be mapped to a two-level system with Ohmic dissipation, which is equivalent to the anisotropic Kondo model. The magnetic response of the impurity spin can serve as a local experimental probe for the order parameter.
The perceptual world of the communication apprehensive: The effect of communication apprehension and interpersonal gaze on interpersonal perception (1980)

This study examined the effects of gaze behavior by interviewees on the interpersonal perception of interviewers. Additionally, the communication apprehension (CA) level of the interviewers was measured. Both the main effects of eye contact and the interactive effect of interviewers’ CA level and eye contact were tested for 11 person‐perception dimensions. Results showed both main effects and interaction effects, indicating the importance of assessing communication behaviors and communication traits in combination. Results also indicated that high communication apprehensives are relatively insensitive to differences in eye contact.
Absence of AGG Interruptions Is a Risk Factor for Full Mutation Expansion Among Israeli FMR1 Premutation Carriers (2018)

<b>Introduction:</b> Fragile X syndrome (FXS) is a common form of X-linked intellectual and developmental disability with a prevalence of 1/4000-5000 in males and 1/6000-8000 in females. Most cases of the syndrome result from expansion of a premutation (55-200 CGGs) to a full mutation (>200 CGGs) repeat located in the 5' untranslated region of the fragile X mental retardation (<i>FMR1</i>) gene. The risk for full mutation expansions increases dramatically with increasing numbers of CGG repeats. Recent studies, however, revealed AGG interruptions within the repeat area function as a "protective factor" decreasing the risk of intergenerational expansion. <b>Materials and Methods:</b> This study was conducted to validate the relevance of AGG analysis for the ethnically diverse Israeli population. To increase the accuracy of our results, we combined results from Israel with those from the New York State Institute for Basic Research in Developmental Disabilities (IBR). To the best of our knowledge this is the largest cohort of different ethnicities to examine risks of unstable transmissions and full mutation expansions among <i>FMR1</i> premutation carriers. <b>Results:</b> The combined data included 1471 transmissions of maternal premutation alleles: 369 (25.1%) stable and 1,102 (74.9%) unstable transmissions. Full mutation expansions were identified in 20.6% (303/1471) of transmissions. A total of 97.4% (388/397) of transmissions from alleles with no AGGs were unstable, 79.6% (513/644) in alleles with 1 AGG and 46.7% (201/430) in alleles with 2 or more AGGs. The same trend was seen with full mutation expansions where 40% (159/397) of alleles with no AGGs expanded to a full mutation, 20.2% (130/644) for alleles with 1 AGG and only 3.2% (14/430) in alleles with 2 AGGs or more. None of the alleles with 3 or more AGGs expanded to full mutations. <b>Conclusion:</b> We recommend that risk estimates for <i>FMR1</i> premutation carriers be based on AGG interruptions as well as repeat size in Israel and worldwide.