gebhart/patrepeval huggingface dataset:
Detection of small-sized near-surface under-clad cracks for reactor pressure vessels (1983)

The analysis of pressurized thermal shock (PTS) shows it is necessary for nondestructive evaluation to demonstrate high probability of detecting evaluation to demonstrate high probability of detecting cracks 0.250 inches deep and deeper at the clad/base metal interface. Ultrasonic techniques developed and used in Europe are evaluated in this paper for their applicability to US reactor pressure vessels for detecting cracks of interest for PTS. Flaw detectability experiments were carried out by testing the inspection technique's ability to detect artificial flaws under several types of clad, including some Manual Metal Arc (MMA) clad. Both ground and unground clad surfaces were evaluated. Crack sizing tests of the inspection technique were made using a crack tip diffraction technique.
GVE-Based Dynamics and Control for Formation Flying Spacecraft (2004)

Formation flying is an enabling technology for many future space missions. This paper presents extensions to the equations of relative motion expressed in Keplerian orbital elements, including new initialization techniques for general formation configurations. A new linear time-varying form of the equations of relative motion is developed from Gauss Variational Equations and used in a model predictive controller. The linearizing assumptions for these equations are shown to be consistent with typical formation flying scenarios. Several linear, convex initialization techniques are presented, as well as a general, decentralized method for coordinating a tetrahedral formation using differential orbital elements. Control methods are validated using a commercial numerical propagator.
Ring opening of 2,3-bis(hydroxymethyl)methylenecyclopropanes with [Fe<sub>2</sub>(CO)<sub>9</sub>]; the molecular structure of a 1,4-diene complex of iron(0), tricarbonyl-η<sup>4</sup>-(3-methylene-4-vinyldiphydrofuran-2(3H)-one) iron (1975)

trans- or cis-2,3-Bis(hydroxymethyl)methylenecyclopropanes react with [Fe2(CO)9] to yield ring-opened products containing the 3-methylene-4-vinyldihydrofuran-2(3H)-one ligand; η2-η4-complexes of this ligand have been characterised, the latter by X-ray crystallography.
Encapsulation of multi-walled carbon nanotubes (MWCNTs) in Ba2+-alginate to form coated micro-beads and their application to the pre-concentration/elimination of dibenzo-p-dioxin, dibenzofuran, and biphenyl from contaminated water (2004)

We report preliminary data on the first use of multi-walled carbon nanotubes as adsorbents for the pre-concentration/elimination of dibenzo-p-dioxin, dibenzofuran and biphenyl from contaminated water.
The arithmetic problem size effect in children: an event-related potential study (2014)

This study used for the first time event-related potentials (ERPs) to examine the well-known arithmetic problem size effect in children. The electrophysiological correlates of this problem size effect have been well documented in adults, but such information in children is lacking. In the present study, 22 typically developing 12-year-olds were asked to solve single-digit addition problems of small (sum ≤ 10) and large problem size (sum > 10) and to speak the solution into a voice key while ERPs were recorded. Children displayed similar early and late components compared to previous adult studies on the problem size effect. There was no effect of problem size on the early components P1, N1, and P2. The peak amplitude of the N2 component showed more negative potentials on left and right anterior electrodes for large additions compared to small additions, which might reflect differences in attentional and working memory resources between large and small problems. The mean amplitude of the late positivity component which follows the N2, was significantly larger for large than for small additions at right parieto-occipital electrodes, in line with previous adult data. The ERPs of the problem size effect during arithmetic might be a useful neural marker for future studies on fact retrieval impairments in children with mathematical difficulties.
P2.10 ASSESSMENT OF CAROTID PULSE WAVE VELOCITY BY ULTRASOUND: A WAVE INTENSITY ANALYSIS-BASED APPROACH (2014)

s 135 Methods: 135 Patients were enrolled in a longitudinal, prospective study of arterial stiffness and cardiovascular risk in a cohort suffering from chronic kidney disease stages 2 to 4. Office measurements of bSBP and aSBP were assessed by a validated oscillometric device. Prognostic factors of survival were identified by use of Cox proportional hazards regression models. Results: After a mean follow up duration of 42 months (range: 30 to 50 months) 13 patients died. In univariate Cox analysis, bSBP did not significantly predict mortality, only aSBP assessed using measured mean and diastolic pressure calibration was significantly associated with mortality (HRZ1.027, pZ0.008). This remained significant in multivariate analysis after adjustment for age, sex and anthropometric measures. More important, adding bSBP to the multivariate model (HRZ0.91, pZ0.003), lead to a significantly increased prognostic and statistical power of aortic systolic pressure (HRZ1.097, p<0.001) and indicated that differences between bSBP and aSBP are of potential interest. Conclusion: Within our cohort, only aSBP assessed with measured mean and diastolic pressure predicted mortality and provided highly significant prognostic value.
Research Needs Assessment for Children With Obstructive Sleep Apnea Undergoing Diagnostic or Surgical Procedures (2018)

Recent concerns have been raised about the quality and safety of adenotonsillectomy, a common surgery performed to treat obstructive sleep apnea (OSA) in children. OSA is a risk factor for opioid-related perioperative respiratory complications including those associated with anoxic brain injury or death. Our objective was to identify controversial issues related to the care of children with OSA. A standardized Delphi consensus technique involving an interdisciplinary group of 24 pediatric OSA experts identified 3 key issues: "postoperative disposition, preoperative screening, and pain management." These topics are prime candidates for future systematic reviews and will guide Society of Anesthesia and Sleep Medicine-related research endeavors.
The role of government in the evolution of the Internet (1994)

article Free Access Share on The role of government in the evolution of the Internet Author: Robert E. Kahn Corp. for National Research Initiatives Corp. for National Research InitiativesView Profile Authors Info & Claims Communications of the ACMVolume 37Issue 8Aug. 1994 pp 15–19https://doi.org/10.1145/179606.179729Published:01 August 1994Publication History 26citation1,956DownloadsMetricsTotal Citations26Total Downloads1,956Last 12 Months62Last 6 weeks14 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my Alerts New Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteeReaderPDF
Emission of fast atoms from a cold Rydberg gas (2006)

Rydberg-Rydberg collisions in a cold, dense Rydberg gas can lead to the conversion of internal energy into center-of-mass energy of the colliding atoms, resulting in Rydberg-atom velocities much larger than the initial velocities in the gas. We prepare cold Rydberg-atom gases by laser excitation of laser-cooled atom clouds and use time-of-flight measurements to demonstrate the production of fast Rydberg atoms. The velocity distributions of Rydberg atoms emerging from the Rydberg-atom gases are obtained. State-selective field ionization spectra indicate a correlation between the production of fast Rydberg atoms and the presence of Penning ionization signatures. The dependence of the yield of fast Rydberg atoms on Rydberg atom density is measured.
Measurements of light background at large depth in the ocean (1985)

The mean intensity of Cerenkov emission from the products of K(40) decay and bioluminescence was measured at depths to 5 km. The intensity of ocean light background is found to depend upon depth and at the 5 km level is equal on averaged to 300 + or - 60 quanta/sq cms into spatial angle of 2 pi sterradian in transparency window. The amplitudes, duration and number of BL flashes were measured at various depths. The intensive flashes due to BL are shown to be observed rather seldom at depths over 4 km.
USE OF ELECTRON SHUTTLES TO BIOLOGICALLY ENHANCE ABIOTIC DECHLORINATION (2006)

as microaerobic systems. In all columns the degradation of c-DCE was observed, however, the removal efficiencies determined by comparing the influent and effluent concentrations were highly inconsistent throughout the experiment. By comparing the background columns to the columns supplied electron donors, it does not appear the addition of vitamins or electron donors enhance the indigenous microorganism`s ability to remove c-DCE. While c-DCE removal within the background column averaged 17%, the vitamin amended control column averaged only 7% c-DCE removal within the column and the electron donor supplied columns averaged between 7% removal and 5% apparent production. Of the electron donors supporting c-DCE removal, benzoic acid demonstrated 7% removal followed closely by propionic acid and n-propanol, both showing 5% c-DCE removal.
Addition of S-1 to the Epidermal Growth Factor Receptor Inhibitor Gefitinib Overcomes Gefitinib Resistance in Non–small cell Lung Cancer Cell Lines with<i>MET</i>Amplification (2009)

Our results suggest that the addition of S-1 to EGFR-TKIs is a promising strategy to overcome EGFR-TKI resistance in NSCLC with MET amplification.
Encapsulation of the Pre‐Formed Cooked Cured‐Meat Pigment (1991)

ABSTRACT The pre‐formed cooked cured‐meat pigment (CCMP) was stabilized by storage under a nitric oxide atmosphere or microencapsulation in food‐grade carbohydrates. Amongst the wall materials tested, β‐cyclodextrin, N‐LOK, and Maltrin M‐250 served as the best encapsulating agents. Presence of gum acacia or a mixture of sodium tripolyphosphate, sodium acid pyrophosphate and ascorbyl palmitate at a 5% level in the wall material(s) improved the color of meats treated with the powdered cooked cured‐meat pigment (PCCMP). Some encapsulated pigments remained stable during an 18 month testing period under refrigeration. Spectral characteristics of PCCMP were similar to those of the freshly‐prepared pigment and color stability of PCCMP‐treated meats was similar to that of nitrite‐cured and CCMP‐treated products.
The Active Site of Staphylococcal Nuclease: Paramagnetic Relaxation of Bound Nucleotide Inhibitor Nuclei by Lanthanide Ions (1974)

The structure of 3',5'-thymidine diphosphate bound in the active site of staphylococcal nuclease (EC 3.1.4.7) was studied by measuring the relaxation rate enhancement of substrate analog nuclei by a paramagnetic metal ion. The lanthanide ion, Gd(III), was substituted for Ca(II) in the formation of the ternary complex of nuclease-Gd(III)-3',5'-thymidine diphosphate. Measurements were made of the transverse relaxation rates of protons and the longitudinal and transverse relaxation rates of the phosphorus nuclei of the bound nucleotide. Internuclear distances between the metal ion and atoms of the 3',5'-thymidine diphosphate nucleotide were determined from these data by the Solomon-Bloembergen equation. In general, these distances corresponded closely to those determined by previous x-ray crystallography of the thymidine diphosphate complex.These internuclear distances were also used with a computer program and graphics display to solve for metal-nucleotide geometries, which were consistent with the experimental data. A geometry similar to the structure of the metal-nucleotide complex bound to nuclease determined by x-ray analysis was one of the solutions to this computer modeling process. For staphylococcal nuclease, the nuclear magnetic resonance and x-ray methods yield compatible high resolution information about the structure of the active site. However, differences of uncertain significance exist between the two structures.
Microwave Pyrolysis of Corn Cob and Characteristics of the Pyrolytic Chars (2009)

Abstract Microwave pyrolysis is a new process for converting biomass to bio-oil, syngas, and solid char. In this study, pyrolysis of corn cob was performed in an inert environment at atmospheric pressure and temperatures ranging from 300 to 600°C. The aim of this work was to study the effect of pyrolysis conditions on the characteristics of the solid char residue. The char was characterized using scanning electron microscopy, Fourier transform infrared spectroscopy, elemental analyzer, BET surface area analysis, and inductive coupled plasma. The char yield from pyrolysis decreased significantly to 23% with an increase in temperature to 600°C. SEM analysis indicated that pyrolysis of corn cob led to a stepwise accumulation of inorganic matter onto the exposed surface, and some organic matter melted, resulting in the formation of hollow cavities by the evolving volatiles. Fourier transform infrared spectroscopy results showed a continuous decrease in the intensity of the hydroxyl group stretch with temperature and the aromatic group to be at maximum at 600°C. Elemental analysis indicated both H/C and O/C ratio decreased continuously with increasing temperature to 450°C then became constant at higher temperatures. Keywords: charcharacterizationcorn cobmicrowave pyrolysis
Triethylborane‐Induced Radical Reactions with Gallium‐ and Indium Hydrides. (2003)

Abstract For Abstract see ChemInform Abstract in Full Text.
Comparative genetic resistance to Ascaridia galli infections of 4 different commercial layer-lines (2003)

1. The objective of the study was to compare the establishment and effect of Ascaridia galli infections in 4 different layer-lines. 2. A total of 160 birds comprising 4 different commercial layer-lines, ISA Brown, New Hampshire, Skalborg and a cross of New Hampshire(NH) and Skalborg (Sk), were infected with A. galli eggs. The birds were examined for the presence of parasite eggs and parasites at weeks 3, 6 and 9 post infection (pi). 3. At week 6 pi the chickens of the NH line harboured more larvae compared with the three other lines. The Sk line chickens excreted more A. galli eggs throughout the study compared with the other lines. Female worms in the Sk line were more fecund than the worms in the other lines. Male and female worms recovered from the Sk line at week 9 pi were longer. Male worms recovered from the NH line 6 weeks pi were shorter than male worms from the other lines. Female worms recovered from the NH line were shorter than the female worms from the ISA line and the Sk line. No differences were seen in weight gain among the 4 lines. 4. The results suggest that genetic factors are involved in the establishment and survival of A. galli in the intestine of layers. Further studies are needed to elucidate the genetic mechanisms behind the observed parasitological findings.
Phase IIa study of single-agent MOR208 in patients with relapsed or refractory B-cell non-Hodgkin’s lymphoma (NHL). (2015)

8500 Background: MOR208 is an Fc-engineered humanized monoclonal antibody that targets the B-cell-specific antigen, CD19. There remains a high unmet medical need for new therapies for patients (pts) with relapsed or refractory (R-R) B-cell NHL. Methods: This is a non-randomized, open-label, multicenter, two-stage, phase IIa study of MOR208 in pts with R-R NHL previously treated with rituximab, who were not candidates for high-dose chemotherapy with stem cell support. Adult pts with diffuse large B-cell lymphoma (DLBCL), mantle cell lymphoma (MCL), follicular lymphoma (FL), or other indolent NHL (iNHL), were treated with single-agent MOR208, 12 mg/kg intravenously, weekly, over two 28-day cycles. Pts with at least stable disease by the 2007 International Response Criteria were to continue MOR208 treatment for another cycle. Pts with complete or partial response (CR or PR) could then receive maintenance MOR208 every 2 or 4 weeks, depending on investigator decision, until progression. Overall response rate (ORR) was the primary endpoint. Results: By 17 November 2014, all pts (n = 89) had been enrolled (DLBCL, n = 35; FL, n = 31; MCL, n = 12; iNHL, n = 11). Thirty-five (39%) pts were female, median age 67 (range 35–90), 78 (88%) had stage III-IV disease, and the median number of prior lines of therapy was 2 (1–4). The mean number of cycles completed was 2.2 (0–3). The investigator-assessed ORR across all NHL subtypes was 22% (20/89) with clinical activity seen in the DLBCL (26% [9/35]; 2 CR, 7 PR; preliminary median duration of response [mDoR] 7.7 months), FL (23% [7/31]; 1 CR, 6 PR; preliminary mDoR 2.6 months) and iNHL (36% [4/11]; 1 CR, 3 PR) cohorts (MCL, 0/12 responses). Grade ≥ 3 non-hematologic and hematologic treatment-emergent adverse events were recorded in 30/89 (34%) and 8/89 (9%) pts, respectively. Infusion-related reactions (8 pts) were all grade 1-2 (except for one case of dyspnea, grade 4). There were no treatment-related deaths. Conclusions: MOR208 demonstrated encouraging single-agent efficacy with CRs observed in pts with R-R DLBCL, FL, and iNHL. MOR208 is well tolerated without significant infusional toxicity. Protocols are being developed to investigate MOR208 in combination with other agents. Clinical trial information: NCT01685008.
Base-Induced Alcoholysis of<i>N</i>-Arylmaleimides: Facile in situ Oxa-Michael Additionto Alkyl Maleanilates: Two-Step One-Pot Rapid Access to AlkoxysuccinicAcids (2003)

A simple, efficient and general two-step, one-pot approach to alkoxysuccinic acids is described. The potassium carbonate-catalyzed reactions of alcohols with N-p-tolylmaleimide (4) followed by an acid-induced hydrolysis of intermediate products furnished alkoxysuccinic acids 1a-f in 90-98% yields. All the intermediates from the reaction of imide 4 with alcohols have been isolated and characterized, proving that the in situ formed alkyl maleanilates 3 are the actual Michael acceptors.
Hereditary Diseases—Causes, Cures, and Problems (1973)

Abstract The nature of the biochemical abnormalities in over a hundred inherited diseases of humans is now convincingly established. This impressive achievement has provided numerous practical benefits, amongst which are: 1. accurate methods for the diagnosis of patients with these diseases; 2. identification of symptom‐free heterozygous carriers of the defective genes; and 3. procedures for the antenatal detection of a large number of these disorders in fetuses. It is anticipated that equally impressive advances will be made in the future regarding the therapy for patients with these diseases who escape prenatal detection, or in cases when an affected fetus is identified but is carried to term in compliance with the decision of the parents. The current concepts regarding the therapy of heritable metabolic diseases are outlined and potential innovations for future corrective procedures are indicated in this report.
Modified silicone rubbers for fabrication and contacting of flexible suspended membranes of n-/p-GaP nanowires with single-walled carbon nanotube transparent contact (2019)

This work proposes new chemical and mechanical materials and techniques for III-V semiconductor NW/silicone membrane formation and optoelectronic device fabrication. Molecular beam epitaxy (MBE)-synthesized n-, p- and i-GaP NWs were encapsulated by introduced G-coating method into synthesized polydimethylsiloxane-graft-polystyrene and released from the Si growth substrate. The fabricated membranes were contacted with different materials including single-walled carbon nanotubes or ferrocenyl-containing polymethylhydrosiloxane with and without multi-walled carbon nanotubes doping. The electrical connection of the fabricated membranes was verified by electron beam induced current (EBIC) spectroscopy. The developed methods and materials can be applied for fabrication of high quality flexible inorganic optoelectronic devices.
Effect of Diazepam on Brain Neurotransmitters, Plasma Corticosterone, and the Immune System of Stressed Rats (1987)

Rats were treated with injections of diazepam (1 or 10 mg/kg) and stressed by restraint lasting 3 hours. This was performed once or, in animals immunized with sheep erythrocytes, repeatedly for 4 consecutive days. After repeated stress and/or diazepam treatment, the levels of brain noradrenalin decreased in all treated groups. Although both treatments (stress and diazepam) diminished the 5-hydroxytryptamine (5-HT)/5-hydroxyindoleacetic acid (5-HIAA) ratio, treatment with either dose of diazepam prevented the stress-induced fall of this ratio. The activity of hypothalamic glutamate decarboxylase, the enzyme taking part in GABA synthesis, was affected neither by the acute nor by repeated stress and/or diazepam treatment. The levels of plasma corticosterone were enhanced in all stressed rats, with and without drug. This finding was in accordance with the enhanced weights of adrenal glands in repeatedly stressed rats. The tendency to a corticosterone rise after repeated treatment with diazepam, 10 mg/kg, coincided with the enhanced weights of adrenal glands in these animals. The plaque-forming cell (PFC) response was reduced in all stressed animals and in animals treated with diazepam, 10 mg/kg. Accordingly, high doses of diazepam given repeatedly to rats are immunosuppressive, achieving this effect presumably by an enhancement of glucocorticoid secretion. Neither the low nor the high doses of diazepam affect the stress-induced enhancement of hypothalamohypophysial-adrenal axis activity and consecutive immunosuppression.
Orientation in base-promoted .beta. eliminations from 2-butyl-N,N-disulfonimides (1975)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTOrientation in base-promoted .beta. eliminations from 2-butyl-N,N-disulfonimidesRichard A. Bartsch, James R. Allaway, David D. Ingram, and Jong-Gun LeeCite this: J. Am. Chem. Soc. 1975, 97, 23, 6873Publication Date (Print):November 1, 1975Publication History Published online1 May 2002Published inissue 1 November 1975https://pubs.acs.org/doi/10.1021/ja00856a051https://doi.org/10.1021/ja00856a051research-articleACS PublicationsRequest reuse permissionsArticle Views59Altmetric-Citations9LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts