gebhart/patrepeval huggingface dataset:
More surprises from <i>Kinetoplastida</i> (1999)

Emotions coordinate our behavior and physiological states during survival-salient events and pleasurable interactions. Even though we are often consciously aware of our current emotional state, such as anger or happiness, the mechanisms giving ...Emotions are often felt in the body, and somatosensory feedback has been proposed to trigger conscious emotional experiences. Here we reveal maps of bodily sensations associated with different emotions using a unique topographical self-report method. In ...
PREPARATION, PROPERTIES AND STRUCTURE OF METAL CONTAINING AMORPHOUS HYDROGENATED CARBON FILMS (1993)

Amorphous hydrogenated carbon (a-C:H) films and hydrocarbon films containing transition metals (Me- C:H) were prepared by glow discharge and reactive sputtering techniques at relatively low substrate temperatures (100 - 200 degree C). The tribological properties of these both types of coating materials will be compared. The Me-C:H films show very low friction coefficients (0.15 equal or bigger than My equal or bigger than 0.05), depending on the used metal as well as on the metal content. Up to now measurements of microhardness and elastic modulus could not reveal a comprehensive understanding of the excellent tribological properties of the Me-C:H films. The experimental results of different analytical investigations can be explained by a structure model consisting of a homogeneous mixture of amorphous carbon (a-C:H) and metal carbides.
Aryl Triflates and [<sup>11</sup>C]/(<sup>13</sup>C)Carbon Monoxide in the Synthesis of <sup>11</sup>C-/<sup>13</sup>C-Amides (2003)

Palladium(0)-mediated carbonylation reactions using aryl triflates, amines, and a low concentration of [(11)C]carbon monoxide were used in the syntheses of 13 (11)C-labeled amides. Lithium bromide was used as an additive to facilitate the reaction. The (11)C-labeled products were obtained with decay-corrected radiochemical yields in the range of 2-63%. The radiochemical purity of the final products exceeded 98%. As an example, a reaction starting with 1.79 GBq [(11)C]carbon monoxide gave 0.38 GBq of LC-purified N-isopropyl-4-nitro-[(11)C]benzamide within 27 min from the start of the carbonylation reaction (54% decay-corrected radiochemical yield). The specific radioactivity of this compound was 191 GBq/micromol, 35 min after the end of a 10 microAh bombardment. N-Benzylisoquinoline-1-((13)C)carboxamide was prepared and analyzed by NMR for confirmation of the labeling position. The triflates 16, 20, 21, and 22 were synthesized from the corresponding alcohols and trifluoromethanesulfonic anhydride. The reference compounds 30a and 30b were prepared from the corresponding carboxylic acids and benzylamine. The other nine reference compounds 32a to 32i were synthesized from the respective acid chlorides and amines. The presented report shows that the sometimes more easily obtainable aryl triflates can be a useful alternative to the commonly used aryl halides in palladium(0)-mediated synthesis of (11)C/(13)C-amides.
Detection of Human Immunodeficiency Virus Type 2 in Brain Tissue (1992)

Journal Article Detection of Human Immunodeficiency Virus Type 2 in Brain Tissue Get access Dominic E. Dwyer, Dominic E. Dwyer Unité d'Oncologie Virale, Institut Pasteur, and Service des Maladies Infectieuses et Tropicales, Hôpital Bichat-Claude Bernard, and Service de Neurologie et Neuropsychologie, Hôpital de la Salpetriere, Paris, France Reprints or correspondence (present address): Dr. Dominic E. Dwyer, Department of Virology, ICPMR, Westmead Hospital, Westmead, NSW, 2145, Australia. Search for other works by this author on: Oxford Academic PubMed Google Scholar Sophie Matheron, Sophie Matheron Unité d'Oncologie Virale, Institut Pasteur, and Service des Maladies Infectieuses et Tropicales, Hôpital Bichat-Claude Bernard, and Service de Neurologie et Neuropsychologie, Hôpital de la Salpetriere, Paris, France Search for other works by this author on: Oxford Academic PubMed Google Scholar Serge Bakchine, Serge Bakchine Unité d'Oncologie Virale, Institut Pasteur, and Service des Maladies Infectieuses et Tropicales, Hôpital Bichat-Claude Bernard, and Service de Neurologie et Neuropsychologie, Hôpital de la Salpetriere, Paris, France Search for other works by this author on: Oxford Academic PubMed Google Scholar Jean-Marie Bechet, Jean-Marie Bechet Unité d'Oncologie Virale, Institut Pasteur, and Service des Maladies Infectieuses et Tropicales, Hôpital Bichat-Claude Bernard, and Service de Neurologie et Neuropsychologie, Hôpital de la Salpetriere, Paris, France Search for other works by this author on: Oxford Academic PubMed Google Scholar Luc Montagnier, Luc Montagnier Unité d'Oncologie Virale, Institut Pasteur, and Service des Maladies Infectieuses et Tropicales, Hôpital Bichat-Claude Bernard, and Service de Neurologie et Neuropsychologie, Hôpital de la Salpetriere, Paris, France Search for other works by this author on: Oxford Academic PubMed Google Scholar Rosemay Vazeux Rosemay Vazeux Unité d'Oncologie Virale, Institut Pasteur, and Service des Maladies Infectieuses et Tropicales, Hôpital Bichat-Claude Bernard, and Service de Neurologie et Neuropsychologie, Hôpital de la Salpetriere, Paris, France Search for other works by this author on: Oxford Academic PubMed Google Scholar The Journal of Infectious Diseases, Volume 166, Issue 4, October 1992, Pages 888–891, https://doi.org/10.1093/infdis/166.4.888 Published: 01 October 1992 Article history Received: 16 December 1991 Revision received: 10 March 1992 Published: 01 October 1992
IL-12 Administered During <i>Chlamydia psittaci</i> Lung Infection in Mice Confers Immediate and Long-Term Protection and Reduces Macrophage Inflammatory Protein-2 Level and Neutrophil Infiltration in Lung Tissue (1999)

Protection against infections with the intracellular bacterium Chlamydia spp. requires Th1-polarized CD4+ T cell immunity. In BALB/c mouse lung infections, immediate innate and nascent Chlamydia-specific immune responses following intranasal inoculation of Chlamydia psittaci strain B577 were modulated by 7-day i.p. administration of murine rIL-12, the initiation cytokine for Th1 immunity. Treatment with IL-12 reduced the severity of chlamydial pneumonia, abolished mortality (37.5% in untreated mice), and significantly reduced numbers of chlamydial organisms in lungs. On day 4 after inoculation, the neutrophil:macrophage ratio in bronchointerstitial pneumonias was 1.96 in untreated mice and 0.51 in IL-12-treated mice. This immediate, IL-12-mediated shift in innate inflammatory phenotype was correlated with a significant reduction of lung concentrations of the neutrophil chemoattractant macrophage inflammatory protein (MIP)-2 (putative murine homologue of human IL-8), monocyte chemotactic protein-1, and TNF-alpha; and a reduction in MIP-1alpha and IFN-gamma, at high-dose infection only, and IL-12-independent IL-10 levels. Chlamydia-specific Ab titers and Ig isotype ratios indicated an IL-12-dependent Th1 shift. Recall responses of IL-12-primed mice to secondary chlamydial lung infection eliminated chlamydiae more effectively and generated a lung cytokine profile conducive to perpetuation of the Th1 memory population. These data support the hypothesis that genetic differences in endogenous IL-12 production and response pathways could determine disease outcomes characterized by poor chlamydial clearance and a purulent inflammatory infiltrate vs effective elimination of chlamydiae in a macrophage-dominated response.
Establishment and characterization of novel in vitro models of gastric chief cell and metaplastic lineages (2012)

Investigations of preneoplastic metaplasias in the stomach are limited by the lack of cell models for mature mucosal cells and metaplasias. We developed in vitro models of chief cells and spasmolytic polypeptide‐expressing metaplasia (SPEM) cells to study the transdifferentiation of chief cells into SPEM. Utilizing the Immortomouse, which is completely transgenic for tempertature‐dependent TAg, chief cells were isolated and cultured from untreated mice. SPEM cells were isolated from mice treated with L635, an acute SPEM induction model. mRNA and protein expression profiles were used to characterize the cultures. ImChief cultures express most chief cell markers with immunostaining for pepsinogen and Rab3D‐containing granules. After 2 weeks at 39°C, ImChief cells cease proliferating and resemble a more differentiated state similar to in vivo chief cells. ImSPEM cells express the SPEM markers TFF2 and HE4 and produce HE4‐containing granules. They lack expression of most other lineage specific markers. ImSPEM cells retain their proliferative ability for at least 1 month at 39°C, resembling the in vivo properties of SPEM cells. Our results indicate that the expression and proliferation profiles of the novel ImChief and ImSPEM cultures resemble in vivo chief and SPEM cell lineages. These cultures provide the first in vitro system for studying the molecular mechanisms of the metaplastic transition in the stomach. Department of Veterans Affairs Merit Review Award and NIH RO1 DK071590
Station keeping of an ROV using vision technology (2002)

This paper will present the results of a demonstration of two degree-of-freedom automatic station keeping of a remotely operated vehicle (ROV) in an ocean environment using vision feedback. This work was done as a collaborative effort in vehicle control between the Aerospace Robotics Laboratory (ARL) and the Monterey Bay Aquarium Institute (MBARI). The results show how the transfer of technology from a testbed autonomous underwater vehicle (AUV) to an ocean-going ROV can be applied to the creation of pilot aids that reduce ROV pilot workload during certain tasks.
ChemInform Abstract: SYNTHETISCHE SCHISTOSOMICIDE 17. MITT. N‐(BENZYLIDEN‐ UND CINNAMYLIDEN)‐N′‐(2‐(DIAETHYLAMINO)‐AETHYL)‐1,4‐NAPHTHALINDIAMINE UND VERWANDTE SCHIFFSCHE BASEN (1970)

Abstract Durch Umsetzung der freien Aminoverbindung mit den entsprechenden aromatischen Aldehyden wurden die Schiffschen Basen (I)‐(VI) dargestellt, die auf schistosomicide Aktivität untersucht wurden.
Molecular Pathways of Drug Resistance (2004)

Despite significant advances in the treatment of solid tumors and hematologic malignancies, clinical drug resistance to anticancer therapy is still a frequent problem that often leads to treatment failure in cancer patients. Resistance to chemotherapy can be divided into intrinsic (or de novo) and acquired resistance. The former refers to tumors that are insensitive to cytotoxic drugs at diagnosis, such as pancreatic cancer, renal cancer, and malignant melanoma. Acquired drug resistance is common in tumors such as breast cancer, small-cell lung cancer (SCLC), and ovarian cancer that initially are highly responsive to anticancer therapy, but become resistant during the course of the disease. These tumors often develop resistance not only to previously used drugs, but also to other compounds with different structures and mechanisms of action to which they have never been exposed.KeywordsAcute Myeloid LeukemiaClin OncolNatl Cancer InstBreast Cancer Resistance ProteinMultidrug Resistance ProteinThese keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
Ion-assisted nucleation and growth of GaN on sapphire(0001) (1998)

We have performed a real-time x-ray scattering study of the nucleation of GaN on sapphire(0001) by gas-source molecular-beam epitaxy. GaN growth using thermal ammonia and ${\mathrm{G}\mathrm{a}(\mathrm{C}}_{2}{\mathrm{H}}_{5}{)}_{3}$ exhibited a rapidly decaying intensity at the 0001 reflection, characteristic of three-dimensional cluster growth. Growth with 30-eV ${\mathrm{NH}}_{x}^{+}$ ions and ${\mathrm{G}\mathrm{a}(\mathrm{C}}_{2}{\mathrm{H}}_{5}{)}_{3}$ exhibited layer-by-layer intensity oscillations with maxima near odd-integer bilayers. The mode of nucleation is controlled by the Ga incorporation efficiency on the substrate and GaN islands. The Ga incorporation efficiency on the substrate is increased by a factor of 4 by low-energy ion irradiation during growth.
A simple pattern correction approach for high frequency surface wave radar on buoys (2006)

The concept of floating antenna array is to replace a conventional coastal receive unit by a sea floating array, constituted of a set of receive buoys. Waves and wind introduce movements of buoys in the array which generate disturbances in the radiation pattern. In this paper, compensation methods for vertical and longitudinal displacements are presented. This document introduces algorithms for both compensation methods. Then, these algorithms are combined in series, providing a simple model method to optimize the radiation pattern of the deformed array.
Pump–probe spectroscopy on photoinitiators for stimulated-emission-depletion optical lithography (2011)

We report on femtosecond pump-probe experiments on two different photoinitiators in solution. These two molecules have recently appeared as attractive candidates for far-field optical lithography based on stimulated-emission-depletion (STED) inspired approaches aiming at beating Abbe's diffraction limit. For the case of 7-diethylamino-3-thenoylcoumarin (DETC), we find that stimulated emission clearly dominates over excited-state absorption, whereas the opposite holds true for the case of isopropylthioxanthone. We argue that it is desirable that stimulated emission dominates over excited-state absorption as depletion mechanism in STED photoresists. Thus, DETC is an attractive corresponding photoinitiator.
Regulation and characterization of the polarity of cells embedded in a reconstructed basement matrix using a three‐dimensional micro‐culture system (2006)

Three cell lines, that is, the human breast cancer cell line (MCF-7) and the human mammary epithelial cell line (S-1) and its malignant form (T4-2) were embedded in a reconstituted basement membrane (Matrigel) that had 20-nL pyramid-shaped silicon microstructures. The proliferative behavior of the MCF-7 cells was dependent on the surrounding conditions (2-D, collagen gel, or Matrigel), whereas the respiratory activity of a single cell (F(c)) was almost identical under different culture conditions. The F(c) value changed with cellular polarity. The F(c) value for the S-1 cells was observed to decrease slightly, whereas that of the T4-2 cells increased 2 days after cultivation in the microstructures within the Matrigel. However, when the T4-2 cells were cultured in the presence of tyrphostin AG 1478 (T4-2 tyr) to inhibit epidermal growth factor (EGF) signaling, the F(c) value decreased slightly and remained almost constant for an additional 1 week; this was similar to the behavior of the S-1 cells. Further, fluorescence images showed that the T4-2 tyr cells formed polar structures that were similar to those formed by the S-1 cells whereas the T4-2 cells did not form such structures. These results indicate that cellular polarity can be assessed by measuring cellular respiratory activity.
An Object is Worth Six Thousand Pictures: The Egocentric, Manual, Multi-image (EMMI) Dataset (2017)

We describe a new image dataset, the Egocentric, Manual, Multi-Image (EMMI) dataset, collected to enable the study of how appearance-related and distributional properties of visual experience affect learning outcomes. Images in EMMI come from first-person, wearable camera recordings of common household objects and toys being manually manipulated to undergo structured transformations like rotation and translation. We also present results from initial experiments, using deep convolutional neural networks, that begin to examine how different distributions of training data can affect visual object recognition, and how the representation of properties like rotation invariance can be studied in novel ways using the unique properties of EMMI.
<b>Postshock Sensing Performance in Transvenous Defibrillation Lead Systems</b>: Analysis of Detection and Redetection of Ventricular Fibrillation (1995)

Redetection of ventricular fibrillation may be delayed in some transvenous lead-pulse generator combinations. Successful redetection of ventricular fibrillation following a failed first shock should be demonstrated prior to hospital discharge of patients with implantable defibrillators.
Extrait de la proposition Controle genetique de la resistance a l'infection salmonellique chez les ovins soumise a l'AIP sur les genes de resistance aux maladies (1993)

*INRA/SAGA Toulouse Diffusion du document : INRA/SAGA Toulouse
Vesicle-associated Membrane Protein 2 Plays a Specific Role in the Insulin-dependent Trafficking of the Facilitative Glucose Transporter GLUT4 in 3T3-L1 Adipocytes (1998)

Vesicle-associated membrane protein 2 (VAMP2) has been implicated in the insulin-regulated trafficking of GLUT4 in adipocytes. It has been proposed that VAMP2 co-localizes with GLUT4 in a postendocytic storage compartment (Martin, S., Tellam, J., Livingstone, C., Slot, J. W., Gould, G. W., and James, D. E. (1996) J. Cell Biol. 134, 625-635), suggesting that it may play a role distinct from endosomal v-SNAREs (soluble N-ethylmaleimide-sensitive factor attachment protein receptors) such as cellubrevin that are also expressed in adipocytes. The present study examines the effects of recombinant glutathione S-transferase (GST) fusion proteins encompassing the entire cytoplasmic tails of VAMP1, VAMP2, and cellubrevin on insulin-stimulated GLUT4 translocation in streptolysin O permeabilized 3T3-L1 adipocytes. GST-VAMP2 inhibited insulin-stimulated GLUT4 translocation by approximately 35%, whereas GST-VAMP1 and GST-cellubrevin were without effect. A synthetic peptide corresponding to the unique N terminus of VAMP2 also inhibited insulin-stimulated GLUT4 translocation in a dose-dependent manner. This peptide had no effect on either guanosine 5'-3-O-(thio)triphosphate-stimulated GLUT4 translocation or on insulin-stimulated GLUT1 translocation. These results imply that GLUT4 and GLUT1 may undergo insulin-stimulated translocation to the cell surface from separate intracellular compartments. To confirm this, adipocytes were incubated with a transferrin-horseradish peroxidase conjugate to fill the itinerant endocytic system after which cells were incubated with H2O2 and diaminobenzidine. This treatment completely blocked insulin-stimulated movement of GLUT1, whereas in the case of GLUT4, movement to the surface was delayed but still reached similar levels to that observed in insulin-stimulated control cells after 30 min. These results suggest that the N terminus of VAMP2 plays a unique role in the insulin-dependent recruitment of GLUT4 from its intracellular storage compartment to the cell surface.
Effects of Pre-conditioning Dose on the Immune Kinetics and Cytokine Production in the Leukocytes Infiltrating GVHD Tissues after MHC-matched Transplantation (2011)

Pre-conditioning dose affected tissue infiltration of leukocytes and cytokine production by myeloid cells in the target organs.
A simple experiment illustrating the structure of association colloids (1979)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTA simple experiment illustrating the structure of association colloidsStig. E. Friberg and Beverly Bendiksen Cite this: J. Chem. Educ. 1979, 56, 8, 553Publication Date (Print):August 1, 1979Publication History Received3 August 2009Published online1 August 1979Published inissue 1 August 1979https://doi.org/10.1021/ed056p553RIGHTS & PERMISSIONSArticle Views216Altmetric-Citations4LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (2 MB) Get e-Alertsclose Get e-Alerts
Simultaneous Recording of Hydraulic-Fracture-Induced Microseisms in the Treatment Well and in a Remote Well (2007)

Abstract In June 2006, in a production well in a tight sandstone shale sequence, on-shore USA, two borehole seismic arrays were deployed in separate wells during a proppant-baring hydraulic fracture treatment. The intent was to delineate the treatment-generated fracture network by recording the microseisms triggered by the treatment, map the microseism source locations, and then use the map as an overlay to delineate the fracture network. The treatment was one facet of a proprietary, multi-faceted injection strategy with microseismic mapping used to determine if neighboring fracture networks overlap. In addition to mapping the network, the objective of this facet was to compare maps from the two arrays. One array was in a remote well, the other in the treatment well. The remote array was offset ~700 ft from the treatment well and at the injection depth. This array was ~500 ft long; self-locking; contained 15, 3-component motion sensors; and operates on a fiber-optic cable. The treatment-well array, the "TABS" or TriAxial Borehole Seismic array (licensed by ExxonMobil Upstream Research), is ~75 ft long; self-locking; operates on a standard, 7-conductor wireline; and includes (1) 3, 3-component motion sensors, (2) an ambient fluid pressure sensor, and (3) a gyroscopic, sensor orientation package. During the treatment, a 45-minute injection immediately followed by a 1-1/2-hour well shut-in, the remote array failed to detect any discernable treatment-triggered, microseisms. However, TABS, which recorded microseismicity only during the shut-in, recorded ~400 microseisms. During the operation, the remote array maintained one position; TABS was unlocked, repositioned, and relocked twice; Moving TABS allowed different perspectives for recording the microseismicity, improving the accuracy of mapping and enhancing additional characteristics extractable from the microseismic waveforms.
Analysis of post-translational modifications of proteins by accurate mass measurement in fast atom bombardment mass spectrometry (1990)

A rotatable dual-target probe was used for accurate mass measurement in fast atom bombardment mass spectrometry to determine the structures of unknown amino acid residues or post-translationally modified structures in peptides or proteins. The results obtained in measurement of tryptic peptides (with molecular weights of up to 2000) of the A-subunit of vero-toxin I indicated that the mass values obtained are sufficiently accurate and reproducible to allow the generation of the possible elemental compositions for modifications in peptides. By this method, the structural modifications of the N-terminal of a recombinant human leukocyte interferon A and novel halogenated amino acids in sperm-activating peptides from the egg-jelly of sea urchins were determined.
Precentral Glioma Location Determines the Displacement of Cortical Hand Representation (1998)

Our data provide evidence for the reorganization of the human motor cortex to allow for preserved hand function in Grade II astrocytomas.
Writing waveguide in pure fused silica with 1 kHz femtosecond laser (2003)

We have investigated the writing of waveguides in pure fused silica glass with femtosecond Ti:sapphire laser at 1 kHz repetition rate. The obtained results were compared for two writing configurations with pulse durations of 200 fs and 45 fs, and with different exposure energies and translation speeds of the sample. The magnitude of the refractive-index changes in the glass was measured as a function of light exposure, where index changes as large as 5×10-3 were achieved.