gebhart/patrepeval huggingface dataset:
Evidence for an electron transfer mechanism in the reduction of ketones by main group metal hydrides (1980)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTEvidence for an electron transfer mechanism in the reduction of ketones by main group metal hydridesEugene C. Ashby, Anil B. Goel, and Robert N. DePriestCite this: J. Am. Chem. Soc. 1980, 102, 26, 7779–7780Publication Date (Print):December 1, 1980Publication History Published online1 May 2002Published inissue 1 December 1980https://pubs.acs.org/doi/10.1021/ja00546a025https://doi.org/10.1021/ja00546a025research-articleACS PublicationsRequest reuse permissionsArticle Views226Altmetric-Citations42LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Studies on Chemotherapy of Tuberculosis. VIII (1955)

Dimethylalkyl-(o-methoxy) phenylammonium bromide (alkyl=butyl, hexyl, octyl, and dodecyl) and dimethylalkyl-(o-dodecyloxy) phenylammonium bromide (alkyl=butyl, octyl, decyl, dodecyl, and tetradecyl) were prepared and their antibacterial action against human type tubercle bacilli was examined in Kirchner's medium. It was found that the latter group possessed some antibacterial action while the former only possessed a weak action and that the length of the alkyl chain, at least up to C12, had no effect on the antibacterial action. Comparison of the effect of O-alkyl and N-alkyl groups on the antibacterial action showed that the size of the alkyl group in O-alkyl did cause a marked difference in the antibacterial action while that of the latter was ineffectual, at least up to C12.
100 W TEM00 Operation of Yb:YAG Thin Disc Laser with High Efficiency (1998)

We report on the power scalability of the thin disc laser design with high efficiency and good beam quality. Nearly 100 W of TEM00 power (M2 = 1.2) with an electrical to optical efficiency of more than of 13% is obtained. A maximum laser power of 346 W was extracted from one single disc with an electrical to optical efficiency of 16.8%.
E-Commerce Vs Women Entrepreneurs. (2018)

In today?s world, women play a major role in every field. Likewise, women are penetrating the e-commerce field and are rising up to face challenges and gain victory one step at a time. This research paper is designed to study the challenges faced by women entrepreneurs in the online e-commerce industry. It is conducted by analyzing the responses received by 25 women entrepreneurs from the e-commerce industry based on various parameters of the challenges faced by them at various intervals.
Ability of Recombinant Human Bone Morphogenetic Protein 2 to Enhance Bone Healing in the Presence of Tobramycin: Evaluation in a Rat Segmental Defect Model (2009)

Although our in vitro results suggested that tobramycin inhibits the osteogenic differentiation of mesenchymal stem cells, this could be overcome by rhBMP-2. Tobramycin did not impair the ability of rhBMP-2 to heal critical-sized femoral defects in rats. Indeed, bone area was increased by nearly 20% in the rhBMP-2 group treated with tobramycin. This study shows that locally applied tobramycin can be used in conjunction with rhBMP-2 to enhance bone formation at fracture sites.
Constant Temperature Constrained Molecular Dynamics:  The Newton−Euler Inverse Mass Operator Method (1996)

The Newton−Euler inverse mass operator (NEIMO) method for internal coordinate molecular dynamics (MD) of macromolecules (proteins and polymers) leads to stable dynamics for time steps about 10 times larger than conventional dynamics (e.g., 20 or 30 fs rather than 1 or 2 fs for systems containing hydrogens). NEIMO is practical for large systems since the computation time scales linearly with the number of degrees of freedom 𝒩 (instead of the 𝒩 3 scaling for conventional constrained MD methods). In this paper we generalize the NEIMO formalism to the Nosé (and Hoover) thermostat to derive the Nosé and Hoover equations of motion for constrained canonical ensemble molecular dynamics. We also examined the optimum mass, Q, determining the time scale (τs) for exchange of energy with the heat bath for NEIMO−Hoover dynamics of polymers. We carried out NEIMO−Hoover simulations on the amorphous polymers poly(vinyl chloride) and poly(vinylidene fluoride), where we find that time steps of 20−30 fs lead to stable dynamics (10 times larger than for Cartesian dynamics). The computational efficiency of the NEIMO canonical MD method should make it a powerful tool for MD simulations of macromolecular materials.
Fungal-Resistant Organotin Resins. (1976)

A series of alkyd resins were prepared that had tin chemically bonded to them. These resins had more resistance to fungal growth than did the original alkyd resins from which they were prepared. This resistance does not appear to be lost as readily by leaching with rain as that of a resin to which bis(tri-n-butyltin) oxide is added as a preservative.
A pilot study on acupuncture for lower urinary tract symptoms related to chronic prostatitis/chronic pelvic pain. (2007)

The preliminary findings, although limited, suggest the potential therapeutic role of acupuncture in the treatment of CP/CPPS. Data from this and previous studies warrant randomized trials of acupuncture for CP/CPPS and particular attention towards acupuncture point selection, treatment intervention, and durability of acupuncture.
NeReLa project: Building network of remote labs using EU best practice (2014)

This paper gives brief presentation of the ongoing Tempus project deals with increasing attractiveness of engineering education in Serbia through innovative teaching methods by introducing remote experimentation as well as trough the strengthening of university-secondary vocational schools collaboration. The project objectives and key activities, which would be carried out in order to produce the expected results, as well as project consortium, are introduced. The best practice in using remote experiments for engineering education at EU partner institutions is elaborated.
WLC24-4: The Destructive Effect of Acknowledgment Traffic in WLANs (2006)

We investigate the interaction between data and acknowledgment (ACK) traffic in Wireless LANs (WLANs) with hidden nodes. The multiple access protocols considered are Carrier Sense Multiple Access (CSMA) and Request-To-Send- Clear-To-Send (RTS-CTS), with access priority given to ACK packets over data packets, as in the IEEE 802.11 standard. The priority given to ACK packets protects them from being destroyed by data packets. We show the converse to hold under RTS-CTS, but not under CSMA, i.e., under the latter protocol ACK packets can destroy data packets. The resulting system capacity is much lower than that predicted by most of the existing studies, where this effect is not accounted for. To boost the performance of CSMA WLANs, we propose and evaluate a technique for grouping ACKs pertaining to different data packet transmissions. Our conclusions are substantiated by an analytical model and further corroborated by simulation.
Recall by genotype and cascade screening for familial hypercholesterolemia in a population-based biobank from Estonia (2018)

Genotype-guided recall of probands and subsequent cascade screening for familial hypercholesterolemia is feasible within a population-based biobank and may facilitate more appropriate clinical management.
Ion Desorption Efficiency and Internal Energy Transfer in Carbon-Based Surface-Assisted Laser Desorption/Ionization Mass Spectrometry: Desorption Mechanism(s) and the Design of SALDI Substrates (2009)

Ion desorption efficiency and internal energy transfer were probed and correlated in carbon-based surface-assisted laser desorption/ionization mass spectrometry (SALDI-MS) using benzylpyridinium (BP) salt as the thermometer chemical. In a SALDI-MS experiment with a N(2) laser (at 337 nm) used as the excitation light source and with multiwalled carbon nanotubes (CNT), buckminsterfullerene (C(60)), nanoporous graphitic carbon (PGC), non-porous graphite particles (G), highly oriented pyrolytic graphite (HOPG), or nanodiamonds (ND) as the SALDI substrate, both the desorption efficiency in terms of ion intensity of BP and the extent of internal energy transfer to the ions are dependent on the type and size of the carbon substrates. The desorption efficiency (CNT approximately C(60) > PGC > G > HOPG > ND) in general exhibits an opposite trend to the extent of internal energy transfer (CNT < C(60) approximately PGC < G approximately HOPG < ND), suggesting that increasing the extent of internal energy transfer in the SALDI process may not enhance the ion desorption efficiency. This phenomenon cannot be explained by a thermal desorption mechanism, and a non-thermal desorption mechanism is proposed to be involved in the SALDI process. The morphological change of the substrates after the laser irradiation and the high initial velocities of BP ions (1100-1400 ms(-1)) desorbed from the various carbon substrates suggest that phase transition/destruction of substrates is involved in the desorption process. Weaker bonding/interaction and/or a lower melting point of the carbon substrates favor the phase transition/destruction of the SALDI substrates upon laser irradiation, consequently affecting the ion desorption efficiency.
Enhancing the performance of accelerated MRI through preservation of acquisition SNR: An “aliased” k‐space approach (2014)

Purpose A method for preserving acquisition SNR through simultaneous acquisitions of distinct k‐space phase encodes to enhance the performance of accelerated MRI is presented. Theory and Methods An excitation module comprising RF pulses and gradients is inserted into a sequence of choice to overlap and acquire distinct k‐space phase encodes. This accelerates a scan as all phase encodes can now be acquired in a duration shorter than that of a typical scan. Next, this “aliased k‐space” is restored during reconstruction using receiver sensitivity profiles. When the aliased k‐space is also sub‐sampled for additional acceleration, Parallel Imaging (PMRI) is applied first to synthesize the unacquired aliased samples. The synthesized samples are then used with the acquired samples in an iterative reconstruction to obtain the output. Results Depending on the sequence, acquisition SNR increased by 18–25% relative to PMRI or by 5% relative to the unaccelerated scan. This compensates for the SNR loss when the aliased k‐space is sub‐sampled for additional acceleration. With PMRI, the method could enable acceleration factors as high as 12 in 2D cartesian scans. Conclusion A method for accelerating MRI scans through aliased k‐space acquisitions and the feasibility of combining the same with PMRI for greater acceleration has been demonstrated. Magn Reson Med 74:150–161, 2015. © 2014 Wiley Periodicals, Inc.
EMQs: a new component of the MRCOG Part 2 exam (2006)

This article describes the background to the decision to introduce Extended Matching Questions into the Part 2 MRCOG written examination. It outlines the customary structure of Extended Matching Questions, using two examples, and describes how they are written. The aims of the paper are to explain the educational and evaluative benefits of adding these questions to the range of examination formats, and to provide some tips to candidates on how to prepare for and successfully attempt them.
Computational modelling of oxygenation processes in enzymes and biomimetic model complexes (2013)

With computational resources becoming more efficient and more powerful and at the same time cheaper, computational methods have become more and more popular for studies on biochemical and biomimetic systems. Although large efforts from the scientific community have gone into exploring the possibilities of computational methods for studies on large biochemical systems, such studies are not without pitfalls and often cannot be routinely done but require expert execution. In this review we summarize and highlight advances in computational methodology and its application to enzymatic and biomimetic model complexes. In particular, we emphasize on topical and state-of-the-art methodologies that are able to either reproduce experimental findings, e.g., spectroscopic parameters and rate constants, accurately or make predictions of short-lived intermediates and fast reaction processes in nature. Moreover, we give examples of processes where certain computational methods dramatically fail.
Transition from Expansion to Shock Compression in Laser Irradiated Si by Multiple Shots (2002)

Picosecond time‐resolved X‐ray diffraction measurements have been performed on laser irradiated Si single crystal. Two types of experiments were performed in air. In one set of experiments, single shot irradiation on the silicon (111) crystal was performed at an irradiance range of 1 – 10 GW/cm2. The results of X‐ray diffraction measurement showed both thermal expansion and transient elastic shock compression. It is deduced that the ablation threshold falls in the range in irradiance of 1 – 10 GW/cm2. The second set of experiments was performed with multiple shot irradiation in the range in irradiance of GW/cm2. Lattice compression due to the multiple laser irradiation was observed. This result indicates that multiple irradiation causes reduction of the ablation threshold.
1‐ versus 2‐ and 3‐day diagnostic patch testing (1996)

One inconvenience of the routine patch test technique is the 2-day patch wear. Adjusting the routine patch test technique to a shorter allergen exposure would be more comfortable for the patient. Studies define this feasibility; the available data do not permit a definite answer as to the suitability of 1-day application. An idealized protocol suitable for resolving this issue is presented.
Turner's syndrome and liver involvement: prevalence and characterization of a large population with Turner's syndrome (2016)

Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
The combination of ultrasound with antibiotics released from bone cement decreases the viability of planktonic and biofilm bacteria: an in vitro study with clinical strains (2006)

This study shows that antibiotic release in combination with ultrasound increases the antimicrobial efficacy further than antibiotic release alone against a variety of clinical isolates. Application of ultrasound in combination with antibiotic release in clinical practice could therefore lead to better prevention or treatment of prosthesis-related infections.
A case of nephrotic syndrome with complications of hyperthyroidism and periodic paralysis. (1990)

症例は26才男性. 12才よりネフローゼ症候群(以下ネ症)の寛解,再発を繰り返す.ネ症寛解期の昭和63年7月頻回に四肢脱力発作出現,精査にて甲状腺機能亢進症に合併した周期性四肢麻痺と診断した(脱力発作時血清K値: 1.9mEq/l).同年11月ネ症再発を認め,尿中T3, T4の排泄増加と共に,血中T3, T4は正常化し脱力発作の消失をみた.本例ではネ症の寛解,再発により甲状腺機能亢進症,周期性四肢麻痺の病態が修飾されたと考えられる.
Neutrophil Accumulation After Traumatic Brain Injury in Rats: Comparison of Weight Drop and Controlled Cortical Impact Models (1994)

Previous work in our laboratory and others using the weight drop (WD) model of traumatic brain injury (TBI) has shown that neutrophils accumulate in brain tissue during the initial 24 h posttrauma as measured by myeloperoxidase (MPO) activity and immunohistochemistry. This study compares the acute inflammatory response to TBI over time, as measured by MPO activity, in the WD and controlled cortical impact (CCI) models. Anesthetized adult Sprague-Dawley rats were traumatized using WD (10-g weight dropped 5 cm) or CCI (4 m/sec, 2.5 mm depth). At 2, 24, 48, or 168 h after trauma, rats (n = 4-5/group at each time) were anesthetized and killed, the brains were removed, and 6-mm coronal slices from traumatized and contralateral hemispheres were assayed for MPO activity. Nontraumatized rats (n = 4) served as controls. Three additional rats underwent a more severe CCI (3 mm depth) with MPO activity assayed at 24 h. A separate group of rats (n = 6) was subjected to WD trauma and killed at 2 weeks after injury for analysis of lesion volume. MPO activity in the traumatized hemisphere was demonstrated at 24 and 48 h in both the WD (0.3152 +/- 0.0472 and 0.3017 +/- 0.0228 U/g, respectively, p < 0.05 vs controls) and CCI (0.1866 +/- 0.0225 and 0.1937 +/- 0.0772 U/g, respectively, p < 0.05 vs controls) models. MPO activity was below the sensitivity of the assay in the control, 2 h, and 168 h groups in both models.(ABSTRACT TRUNCATED AT 250 WORDS)
2010. A Significant Reduction in Empiric Vancomycin Days of Therapy for Suspected MRSA Pneumonia in Adult Non-ICU Patients After Implementation of a Rapid MRSA Nasal PCR Test with Antimicrobial Stewardship Intervention (2019)

Abstract Background Methicillin-resistant Staphylococcus aureus (MRSA), when implicated in respiratory tract infections, can be associated with significant morbidity and mortality. The prevalence of severe MRSA pneumonia may be as high as 10%; however, recent evidence suggests that MRSA is much less prevalent as a cause of community-acquired pneumonia (CAP) among community-dwelling patients and may be as low as 0.1%. Nonspecific features of pneumonia in non-ICU patients (viral co-infection, multi-lobar infiltrates) often lead clinicians to cautiously initiate empiric anti-MRSA therapy. Recommendations of when to safely de-escalate empiric treatment prior to known respiratory cultures are not established. To decrease anti-MRSA therapy in non-ICU pneumonia patients with a low probability of MRSA pneumonia, we employed a nasal screening paired with antimicrobial stewardship intervention. Methods A retrospective, single-center, pre-post interventional study was conducted at Northwestern Memorial Hospital (NMH), in Chicago, IL, to assess the duration of empiric vancomycin for suspected MRSA pneumonia in non-ICU patients before (January 2019) and after (March 2019) the implementation of a rapid MRSA nasal PCR test. During the post-implementation period, an NMH Antimicrobial Stewardship (AS) member identified and assessed the daily (M-F) use of empiric vancomycin for pneumonia in non-ICU patients. When vancomycin use criteria were not met, the AS pharmacist requested the team order a BD MRSA Nasal PCR test (NPV: 97.2%) to classify patients as either possible MRSA pneumonia or unlikely MRSA pneumonia. Results of a negative MRSA Nasal PCR with an ongoing clinical disposition not suggestive of MRSA pneumonia prompted the AS pharmacist to recommend de-escalation of vancomycin. Results See table. Conclusion The use of a rapid MRSA nasal PCR test with active antimicrobial stewardship intervention significantly reduced the duration of empiric vancomycin in hospitalized non-ICU patients with suspected MRSA pneumonia. Disclosures All authors: No reported disclosures.
Multifeature Anisotropic Orthogonal Gaussian Process for Automatic Age Estimation (2017)

Automatic age estimation is an important yet challenging problem. It has many promising applications in social media. Of the existing age estimation algorithms, the personalized approaches are among the most popular ones. However, most person-specific approaches rely heavily on the availability of training images across different ages for a single subject, which is usually difficult to satisfy in practical application of age estimation. To address this limitation, we first propose a new model called Orthogonal Gaussian Process (OGP), which is not restricted by the number of training samples per person. In addition, without sacrifice of discriminative power, OGP is much more computationally efficient than the standard Gaussian Process. Based on OGP, we then develop an effective age estimation approach, namely anisotropic OGP (A-OGP), to further reduce the estimation error. A-OGP is based on an anisotropic noise level learning scheme that contributes to better age estimation performance. To finally optimize the performance of age estimation, we propose a multifeature A-OGP fusion framework that uses multiple features combined with a random sampling method in the feature space. Extensive experiments on several public domain face aging datasets (FG-NET, MORPH Album1, and MORPH Album 2) are conducted to demonstrate the state-of-the-art estimation accuracy of our new algorithms.
High Strengthening of PAN-based Carbon Fiber by Imposing of a High Magnetic Field in Graphitization Process (2000)

A high static magnetic field was imposed on PAN-based carbon fibers in the graphitization process. Oxidized fibers were graphitized in the magnetic field of 12 T and at the temperature of 2, 273 K. Samples were made under the magnetic fields perpendicular to fiber axis and parallel to it. The latter treatment has improved the tensile strength more than the former does. In the both samples the increase of the tensile strength more than 30% has been achieved by imposing the magnetic field. The reason of improvement of the tensile strength is discussed from the view points of magnetic energies difference due to the magnetic anisotropy of a six carbocyclic ring and of flaws on a fiber.
Cercaricidal activity of phenylheptatriyne and α-terthienyl, naturally occurring compounds in species of Asteraceae (Compositae) (1980)

The susceptibility of some digenetic trematode cercariae to the polyacetylene phenylheptatriyne (PHT), from leaves of Bidens pilosa L. (Compositae), and the thiophene α-terthienyl (α-t), from roots of Tagetes patula L. (Compositae), with and without ultraviolet (UV) activation, was examined. In darkness the lethal concentration for 100% (LC 100 ) for both substances was 0.3 ppm. Under UV irradiation of 300–400 nm and incident intensity of 6 W/m 2 , the LC 100 for PHT was not markedly lowered, but for α -t it was reduced by a factor of 30 (to 0.01 ppm). A cercaricidally effective aqueous infusion (1:1000) of Tagetes roots protected the snail hosts Physa occidentalis Tyron (Physidae) from bacterially complicated death but did not reduce cercarial production or predispose the emerging cercariae to subsequent UV injury.
Homogentisic acid is the primary precursor of melanin synthesis in Vibrio cholerae, a Hyphomonas strain, and Shewanella colwelliana (1995)

The enzyme p-hydroxyphenylpyruvate hydroxylase (HPPH) is involved in pigmentation (pyomelanin) via homogentisic acid (HGA). Pyomelanin formation is correlated with HGA production and expression of HPPH in three disparate marine species: Vibrio cholerae, a Hyphomonas strain, and Shewanella colwelliana. Induction of pigmentation in V. cholerae 569B by nutrient limitation also correlated with production of HGA.
Design of an annular slot for microwave dielectric measurements (2005)

A new technique using the multi-port annular slot antenna for the measurement of complex permittivity is developed. The benefit of this new technique is that a two port network can be used on a planar device without excision of the sample. A simple but effective calibration technique to compensate for the feed network is used to obtain the measured permittivity for methanol. The validity of the method is confirmed by comparing the expected and measured results.