gebhart/patrepeval huggingface dataset:
Effect of the Lupus Anticoagulant on Endothelial Fibrinolytic Activity In Vitro (1989)

We investigated the effect of plasma and serum from 10 subjects with the lupus anticoagulant and thrombosis and 9 normal subjects on the secretion of tissue-type plasminogen activator (t-PA) and its rapid inhibitor (type 1 plasminogen activator inhibitor, or PAI-1) by cultured human endothelial cells. Confluent monolayers of human umbilical vein endothelial cells were incubated for 48 hours with plasma or serum diluted ten-fold in serum-free endothelial cell growth medium, and the secretion of t-PA and PAI-1 measured by enzyme-linked immunosorbent assay. No consistent differences in mean t-PA and PAI-1 release were found between cells exposed to normal plasma or serum and plasma or serum from subjects with the lupus anticoagulant and thrombosis. No plasma or serum sample produced consistent inhibition of t-PA release or stimulation of PAI-1 release (defined as t-PA levels less than the mean minus two standard deviations for normal subjects, and PAI-1 levels greater than the mean plus two standard deviations for normal subjects, respectively). These findings do not support a role for altered endothelial fibrinolytic activity in the pathogenesis of thrombosis in subjects with the lupus anticoagulant, and are consistent with previous observations that these subjects have normal fibrinolytic activity in vivo.
Wide-Baseline Stereo-Based Obstacle Mapping for Unmanned Surface Vehicles (2018)

This paper proposes a wide-baseline stereo-based static obstacle mapping approach for unmanned surface vehicles (USVs). The proposed approach eliminates the complicated calibration work and the bulky rig in our previous binocular stereo system, and raises the ranging ability from 500 to 1000 m with a even larger baseline obtained from the motion of USVs. Integrating a monocular camera with GPS and compass information in this proposed system, the world locations of the detected static obstacles are reconstructed while the USV is traveling, and an obstacle map is then built. To achieve more accurate and robust performance, multiple pairs of frames are leveraged to synthesize the final reconstruction results in a weighting model. Experimental results based on our own dataset demonstrate the high efficiency of our system. To the best of our knowledge, we are the first to address the task of wide-baseline stereo-based obstacle mapping in a maritime environment.
Determination of amino acid requirements by indicator amino acid oxidation: applications in health and disease (1998)

Indispensable amino acid requirements for children, patients and pregnant women are largely unknown. We describe a new, non-invasive technique that can estimate requirements in vulnerable populations. Future applications will lead to optimal nutritional care for populations in which an appropriate balance of amino acids is essential for metabolic health and growth.
Electromechanical speed map development using FNET/GridEye frequency measurements (2014)

Differences in electromechanical wave propagation speeds have long been observed in different regions of the power grid. Various attempts have been made over the years to develop “speed maps” of the grid, either through analytical means or from measurements. Analytical techniques are computationally difficult and require that an accurate model of the system be known a priori, which is generally impossible for a large system such as the Eastern Interconnection. Most, if not all, of measurement-based techniques introduced to-date assume constant propagation speed between the disturbance source and the sensor, which does not reflect reality. This paper presents a new method for developing speed maps using FNET/GridEye data from confirmed disturbances that seeks to eliminate many of the issues faced by previous attempts.
I like to build things (1999)

SUBTITLE: WALTER CHRYSLER FELL IN LOVE WITH A CAR IN 1907 AND THEN LEFT RAILROADING TO CREATE THE THIRD-BIGGEST AUTO COMPANY AND THE BEST- ENGINEERED VEHICLES OF HIS DAY.
Einfluss der Nachbehandlungsart auf den Widerstand von Beton gegen Frost und Taumittel. (1988)

Abstract Es wird über Laborversuche zur Bestimmung des Einflusses baupraktischer Nachbehandlungsverfahren im Vergleich zu einer laborüblichen, fünftägigen Wasserlagerung der Proben berichtet. Herkömmliche Abdeckungen mit feuchten Matten und/oder Verdunstungsschutzfolien erwiesen sich als wirkungsvolle Nachbehandlungsverfahren. Flüssige Nachbehandlungsmittel brachten dagegen einen ungünstigen Einfluss auf den Widerstand.
Host finding by aphids in the field (1961)

SUMMARY The spectral energy distribution of the light reflected from various leaves and soils has been measured and corrected for ‘standard’ sunlit conditions, and then compared on the basis of Moericke's evidence that aphids of many species distinguish two parts of the spectrum as colours, alighting and probing in response to wavelengths greater than 500μ. Alightments by Brevicoryne brassicae and Myzus persicae in the field occurred preferentially on leaves reflecting a greater proportion of long‐wave energy, with little or no regard for the ‘botanical’ (plant‐taxonomic) host status of the plants for each aphid. The colour attraction of such ‘yellow‐sensitive’ aphids serves rather to bias their alightments towards plants of the appropriate physiological type. Laboratory experiments confirmed the existence, inferred from field observations, of a second, non‐specific mechanism of visual attraction normally involved in alightments on plants, namely a close‐range optomotor reaction with both orienting and arresting components. The light reflected from various soils embodied maximum energy at the extreme long‐wave end of the spectral range affecting aphids, while the leaf energy peak was 540–560 mμ. The predominantly long‐wave emission from both leaves and soils contrasts sharply with the light from clear or clouded skies, wherein the peak energy region lies below 500 mμ. The aphids' type of colour vision thus provides for a primary discrimination between sky and ground, beside any subsidiary discriminations among plants and soils. Low‐flying Aphis fabae were attracted to white surfaces as well as to yellowing leaves in the field. The change in the migrant's behaviour from ‘distance flight’ in the upper air to low‐level ‘alighting flight’ appears to be due, not to a reversal of the response to short‐wave sky light from positive to negative, but simply to a relative strengthening of the positive response to long‐wave light from the ground.
Introduction to Aircraft Performance, Selection, and Design (1984)

Aircraft Forces and Subsystems. Level Flight in the Vertical Plane: Turbojets. Other Flight in the Vertical Plane: Turbojets. Turning Flight in the Horizontal Plane: Turbojets. Level Flight in the Vertical Plane: Piston-Props. Other Flight: Piston-Props. Turboprops, Turbofans, and Other Things. Figures of Merit for Selection and Design. Effects of Wind on Performance. Stability and Control Considerations. Some Design Examples. Appendixes.
Application Study on Image Mark Comparison Method (2011)

According to the lowness of precision and efficiency of image mark artificial comparison,this paper proposes mean absolute difference algorithm based on feature points of image mark test.Translation and rotation transformation in space rectangular coordinate system are used in establishing error analysis model to modify 3Ddata.According to de-noising theory of wavelet analysis,threshold value treatment was selected to establish de-noising model and conduct de-noising treatment to the data.Feature points are extracted with the method based on minimum approximation error and data automatic comparison is carried out to put out mark similarity data theory.The result shows that comparison efficiency and result precision improve significantly after using the method.
Simple and accurate loss measurement technique for semiconductor optical waveguides (1985)

Loss figures for GaAs/GaAlAs heterostructure optical waveguides have been derived from Fabry-Perot cavity resonances. These correlate with the mean guide transmissions within ±0.5 dB for 75% of the guides measured, for losses up to 12 dB per pass.
Interactions Study of Self Optimizing Schemes in LTE Femtocell Networks (2012)

Thesis (Master, Electrical & Computer Engineering) -- Queen's University, 2012-12-05 22:35:27.538
Advanced Oxidation of Bromide-Containing Waters:  Bromate Formation Mechanisms (1998)

Bromate formation in ozone-based advanced oxidation processes (AOPs) was investigated by laboratory experiments in combination with kinetic modeling. Oxidant concentra tions were monitored during the experiments, which allows us to account for the relative contributions of ozone and OH radical pathways. It has been shown by γ-ir radiation of bromide-containing solutions in the pH range 6−8 that bromate can be formed by a pure OH radical mechanism and that hypobromous acid/hypobromite (HOBr/OBr-) is a requisite intermediate in bromate formation. The presence of hydrogen peroxide (H2O2), as in H2O2-based AOPs, leads to a reduction of HOBr/OBr- and therefore becomes a key reaction for the control of bromate formation. The steady-state concentration of OH radicals in AOPs is usually not high enough to compensate for this reduction reaction. Therefore, in γ-irradiation experiments, no bromate was formed in the presence of H2O2 because OH radicals were the only possible oxidants to further oxidize HOBr/OBr-. However, in ozone-based AOPs at pH 7, where ozone is present in combination with H2O2, bromate was still formed. This was attributed to the oxidation of Br• by O3, which was investigated at pH 7. Our experimental findings could be best explained by a corresponding second-order rate constant k = 1.5 × 108 M-1 s-1.
Enhancement of acute allergic inflammation by indomethacin is reversed by prostaglandin E2: apparent correlation with in vivo modulation of mediator release. (1988)

Intravital microscopy and determination of in vivo histamine release revealed that the cyclooxygenase inhibitor indomethacin reduced antigen-induced vasodilation while enhancing plasma extravasation, leukocyte accumulation, and histamine release in cheek pouches of immunized hamsters. Topical application of prostaglandin E2 (PGE2, 30 nM) totally reversed the indomethacin-induced potentiation of the inflammatory reaction to antigen challenge and suppressed both the histamine release and plasma leakage also in the absence of indomethacin. On the other hand, PGE2, which per se caused vasodilation, markedly potentiated the postcapillary leakage of plasma induced by histamine or leukotriene C4, as well as the leukocyte activation and subsequent plasma extravasation evoked by leukotriene B4. Taken together, the data indicate that PGE2 reduced the antigen response by suppression of mediator release from the numerous mast cells present in the cheek pouch. Moreover, the PGE2-sensitive potentiation by indomethacin of the antigen response suggests that endogenous vasodilating prostaglandins (possibly PGE2) predominantly were anti-inflammatory.
The Late Second Coming of the Automobile (1993)

The automobile has produced dramatic changes in economy and lifestyles. It has generated a significant technology system and infrastructure, but it is my contention that the latter has become a symbol of yesterday's technology systems similar to tube-based televisions and electronics and the mainframe computer of recent times. Major technology and management systems changes are needed to bring the relative cost/price of an automobile back to the range of being a good value for the money to make it a competitive consumer product.
Functional endoscopic sinus surgery--I (Anatomy, diagnosis, evaluation and technique). (1991)

It has been proved beyond doubt that the causation and perpetuation of disease in the dependent sinuses (maxillary and frontal sinuses) is secondary to disease of the ostiomeatal complex, the primary focus of which is the anterior ethmoid. Based on this concept, functional endoscopic sinus surgery (FESS) aims at correcting the underlying pathology in the ethmoids and helps to re-establish normal ventilation and mucociliary clearance of the dependent sinuses.
Color Uniformity Improvement for an Inkjet Color 3D Printing System (2016)

A hybrid 3D color dithering method is proposed to improve image quality of a 3D color inkjet printing system. The method extends the conventional two-dimensional ordered dithering into 4 layers with 3-axis optimization. It results in smoother color mixing in multiple viewing directions by stacking and distributing the color ink-drop evenly in each of 4 × 4 × 4 voxels in a 3D print. 3D color error diffusion also applies to texture-rich areas to enhance its sharpness. A method to measure and compensate the color differences of a 3D print in different surface directions also is proposed to improve the consistency of color across different faces of the print.
A retrospective study on the safety of immunotherapy in pregnancy (1993)

Eighty-one Indian patients received immunotherapy for allergic diseases during 109 pregnancies. Their allergy clinic records were analysed retrospectively and this revealed an incidence similar to or less than the general population with regard to abortion, perinatal mortality, prematurity, toxaemia and congenital malformation. A control group of 60 contemporary Indian patients (82 pregnancies) who refused immunotherapy were also analysed retrospectively and this revealed a higher incidence of abortion, prematurity and toxaemia as compared with those treated with immunotherapy. It is concluded that immunotherapy for allergic diseases is safe in pregnancy. Immunotherapy is safe even when it is initiated for the first time in a pregnant patient, an aspect not reported in any study until now.
Review on Haploidentical Hematopoietic Cell Transplantation in Patients with Hematologic Malignancies (2016)

Allogenic hematopoietic cell transplantation (HSCT) is typically the preferred curative therapy for adult patients with acute myeloid leukemia, but its use has been reduced as a consequence of limited donor availability in the form of either matched-related donors (MRD) or matched-unrelated donors (MUD). Alternative options such as unrelated umbilical cord blood (UCB) transplantation and haploidentical HSCT have been increasingly studied in the past few decades to overcome these obstacles. A human leukocyte antigen- (HLA-) haploidentical donor is a recipient's relative who shares an exact haplotype with the recipient but is mismatched for HLA genes on the unshared haplotype. These dissimilarities pose several challenges to the outcomes of the patient receiving such a type of HSCT, including higher rates of bidirectional alloreactivity and graft failure. In the past 5 years, however, several nonrandomized studies have shown promising results in terms of graft success and decreased rates of alloreactivity, in part due to newer grafting techniques and graft-versus-host disease (GVHD) prophylaxis. We present here a summary and review of the latest results of these studies as well as a brief discussion on the advantages and challenges of haploidentical HSCT.
The evolution of virus–induced apoptosis (1997)

Viruses from several different families are able to exploit their host's cell death programmes so as to maximize viral fitness. Consideration of the evolution of such strategies has lead to the suggestion that the virus should inhibit apoptosis, in order to prolong the life of the cell and thereby maximize the number of progeny virions. The host, on the other hand, should stimulate apoptosis thereby inhibiting viral growth and blocking viral spread. For example, the function of the latent membrane protein I (LMPI) of the Epstein-Barr virus and the bcl-2 homologue gene A179L of African swine fever virus is to inhibit apoptosis. However, in other cases it is the virus that stimulates cell death or the host that benefits from inhibiting apoptosis, such as in fatal alphavirus encephalitis. This has been explained by assuming that virus-induced apoptosis in non-regenerating cells would be detrimental to the host. We present a mathematical framework for understanding virus-induced apoptosis which accounts for these two opposite solutions to virus infection with respect to the mode of virus replication and the life cycle of the target cell.
Magnetostatic wave terminations (1978)

Magnetostatic waves (MSW) propagating in low line-width (ΔH&lt;0.5 Oe) yttrium iron garnet (YIG) films grown by liquid phase epitaxy (LPE) constitute a potential basis for analog signal processing directly at microwave frequencies (1–20 GHz). MSW device techniques are complementary to those utilized in surface acoustic wave (SAW) devices at VHF/UHF. A necessary prerequisite for a high performance MSW analog signal processing technology is a low insertion loss (&lt;20 dB) delay line with low passband ripple (&lt;2 dB). Shorted, narrow microstrip transducers readily provide the low insertion loss; thus, the major problem is that of terminating unwanted waves within the YIG samples. Unterminated magnetostatic forward volume wave (MSFVW) delay lines can easily have passband ripple in excess of 20 dB. By measuring the frequency periodicities of these ripples in the passband and the corresponding group delays, all sources of reflection have been identified. Terminations consisting of magnetic recording tape, ferrite powder slurries, and surface-abraded YIG have been tested on the YIG end regions. The MSFVW passband ripple has been reduced to less than 2 dB, over the 500 MHz band from 2.7 to 3.2 GHz, in a reproducible manner.
Avaliação da qualidade de vida de mulheres idosas na comunidade (2014)

Qualidade de vida na velhice e feminizacao da velhice sao fenomenos que chamam a atencao de demografos, geriatras e gerontologos sociais. O objetivo deste estudo foi avaliar a qualidade de vida de mulheres idosas cadastradas em uma Unidade Basica de Saude do municipio de Sao Paulo. Trata-se de um estudo de abordagem quantitativa, no qual participaram 211 mulheres idosas. Foram coletados dados sociodemograficos e aplicacao do instrumento Whoqol-Old para avaliacao da qualidade de vida. As idosas que participaram deste estudo eram em sua maioria, idosas jovens na faixa etaria de 60 a 69 anos ( p valor <0,001) , afrodescendentes ( p valor <0,001) , sem conjuge ( p valor <0,001) , vivendo em lares multigeracionais, analfabetas, aposentadas, com renda mensal de 1 a 3 salarios minimos, pouco acesso ao lazer, inatividade fisica, dependentes do Sistema Unico de Saude para tratamento de doencas cronicas: hipertensao arterial e Diabetes. Observou-se que na avaliacao da qualidade de vida, as facetas intimidade (media 11,6) e (DP 4,6) e atividades presente, passadas e futuras (media 11,7) e (DP 11,5) obtiveram os piores escores de qualidade de vida. Concluiu-se que a avaliar a qualidade de vida das mulheres idosas e fundamental para o cuidado a este seguimento crescente no Brasil. Descritores : Qualidade de vida ; Enfermagem; Idosos . Normal 0 21 false false false PT-BR X-NONE X-NONE
Language-Neutral Representation of Syntactic Structure (2002)

The unrelated GSK-3 and CK1 families stand out among the protein kinases because of their phosphorylated substrate recognition sites. Two papers in the March 22nd issue of Cell highlight the importance of this priming phosphorylation for signal transduction during development.
Introns Are Inconsequential to Efficient Formation of Cellular Thymidine Kinase mRNA in Mouse L Cells (1987)

TK mRNA levels were determined in mouse L cells transformed with intron deletion mutations of the chicken TK gene. Whether normalized per cell, per integrated gene, or per internal control signal, intron deletion did not diminish the efficiency of TK mRNA formation in transformed L cells. The results demonstrated that introns are not required for efficient biogenesis of cellular mRNA in transformed mouse L cells.
ASCO 2008 Report: Breast Cancer (2008)

Zoledronic Acid Prolonged Disease-Free and Relapse-Free SurvivalOn behalf of colleagues in the Austrian Breast Cancer Study Group (ABCSG), Michael
Human migraine models. (2001)

The need for experimental models is obvious. In animal models it is possible to study vascular responses, neurogenic inflammation, c-fos expression etc. However, the pathophysiology of migraine remains unsolved, why results from animal studies not directly can be related to the migraine attack, which is a human experience. A set-up for investigations of experimental headache and migraine in humans, has been evaluated and headache mechanisms explored by using nitroglycerin and other headache-inducing agents. Nitric oxide (NO) or other parts of the NO activated cascade seems to be responsible for the induced headache and migraine. Perspectives are discussed.
PAT1, a microtubule-interacting protein, recognizes the basolateral sorting signal of amyloid precursor protein (1998)

In epithelial cells, sorting of membrane proteins to the basolateral surface depends on the presence of a basolateral sorting signal (BaSS) in their cytoplasmic domain. Amyloid precursor protein (APP), a basolateral protein implicated in the pathogenesis of Alzheimer's disease, contains a tyrosine-based BaSS, and mutation of the tyrosine residue results in nonpolarized transport of APP. Here we report identification of a protein, termed PAT1 (protein interacting with APP tail 1), that interacts with the APP-BaSS but binds poorly when the critical tyrosine is mutated and does not bind the tyrosine-based endocytic signal of APP. PAT1 shows homology to kinesin light chain, which is a component of the plus-end directed microtubule-based motor involved in transporting membrane proteins to the basolateral surface. PAT1, a cytoplasmic protein, associates with membranes, cofractionates with APP-containing vesicles, and binds microtubules in a nucleotide-sensitive manner. Cotransfection of PAT1 with a reporter protein shows that PAT1 is functionally linked with intracellular transport of APP. We propose that PAT1 is involved in the translocation of APP along microtubules toward the cell surface.
CO<sub>2</sub>-promoted oxidative cross-coupling reaction for C–S bond formation via masked strategy in an odourless way (2015)

Cu-catalyzed direct oxidative cross-coupling between boronic acids and masked sulfides delivering thioethers was described, in which the SO3(-), as a mask, has shown a distinctive effect on the oxidative cross-coupling condition. Disulfide could be suppressed efficiently via masked strategy under CO2 atmosphere. A broad scope of aromatics and scalable processes indicates its practicality, which could be further applied to drug late-stage modification and unsymmetrical dibenzothiophenes (DBTs) synthesis.
A CIRCULARLY POLARIZED ANTENNA ARRAY WITH A CONVENIENT BANDWIDTH/SIZE RATIO BASED ON NON-IDENTICAL DISC ELEMENTS (2015)

This paper presents design and development of a Circularly Polarized microstrip antenna array for C-band application. The proposed antenna exhibits convenient trade-off between bandwidth and dimension. The array design is based on the Sequential Phase Arrangement (SPA) of 2×2 non-identical disc based patch elements, operating in modal degeneration. Exploiting the properties of the SPA, capable to force CP even operating on linear polarized elements, each disc is independently detuned to operate on non perfectly overlapped bandwidth. When properly fed by a Sequential Phase Network (SPN), the set of four discs seamlessly covers the wide cumulative bandwidth which is the combination of the four sub-channels. To verify the design, a single-layer via-less array is fabricated in a compact printed square board of side 40 mm, meaning a surface of 0.64λ20 at the center frequency of 6.0 GHz, assembling the elements with a compact space-filling SPN. The measurements show a wide 10 dB return loss bandwidth of 28.5%, a 3 dB Axial Ratio (AR) bandwidth exceeding 1 GHz, and a realized gain ranging from 4.1 dB to 7.25 dB inside the AR bandwidth. The global bandwidth of the proposed array, almost coincident with the AR bandwidth, is 17.0%.