gebhart/patrepeval huggingface dataset:
POSSIBILITY OF CONCENTRATION POLARIZATION OCCURRING INSIDE THE MEMBRANE DURING STEADY STATE PERVAPORATION (1996)

Mathematical equations are derived for describing the pervaporation transport of pure penetrant through polymeric membranes by assuming the chemical potential gradient as the driving force for the flow of penetrant. An imaginary phase (liquid or vapor) is assumed to be present and is in thermodynamic equilibrium with the membrane phase for deriving these equations. The mathematical equations obtained are similar to those derived by Okada and Matsuura (1991) using the pore-flow model. The possibility of concentration polarization occurring inside the membrane is predicted based on the analysis of binary mixture pervaporation. Experimental profiles of binary penetrant concentration in the membrane are established and these profiles substantiate the prediction of concentration polarization occurring inside the membrane. Pervaporation and sorption data from liquid and vapor phase at 25°C are reported for the acetic acid-water-polyamide system.
Fluorescence depolarization measurements under shock compression (2017)

Measurements of the time-dependent fluorescence depolarization of emissive probe molecules enable real-time observations of molecular rotations in shocked materials. In shocked solids, molecular rotations occur as a result of shear deformations. An apparatus is described to measure time-dependent fluorescence depolarization of shocked materials using laser-driven flyer plates and either a picosecond or a nanosecond probe laser. The emission was separated into parallel and perpendicular channels and imaged onto a streak camera. Time-dependent fluorescence depolarization of rhodamine 6G (R6G) dye dissolved in poly-methyl methacrylate (PMMA) was measured with a 16 ns duration impact at 1 km s−1. A partial depolarization of the dye emission was observed to occur during a 150 ns period after the shock.
An informationally-open, organizationally-closed control structure for navigating a robot in an unknown, stationary environment (2003)

This paper examines the roots of purposive behavior in an agent surrounded by a stationary unknown environment. The investigation focuses on deriving a structure for a behavior generation mechanism (BGM) that would semantically embed an agent in the context of its environment. The BGM is made to adhere to the situated, embodied, intelligent, and emergent requirements that were suggested by Brooks for the construction of intelligent control architectures. Concepts from epistemology, artificial life, hybrid systems, and the potential field approach to planning are used. The suggested BGM utilizes both experience and synergy as drivers of action selection. The BGM is intended for use in the specific case of motion planning for a multidimensional agent of arbitrary shape operating in a multidimensional, unknown environment.
Pathogenetic Tropism of Varicella‐Zoster Virus to Primary Human Hepatocytes and Attenuating Tropism of Oka Varicella Vaccine Strain to Neonatal Dermal Fibroblasts (2003)

The pathogenesis of varicella-zoster virus (VZV) was characterized by the cell tropism of the original Oka and attenuated Oka varicella vaccine strains. Among the tissue cells examined, VZV replicated best in hepatocytes and second best in lung fibroblasts. The high affinity to hepatocytes and lung fibroblasts might correlate with varicella hepatitis and pneumonia and with autopsy observations of varicella. Cell tropism may be important in understanding the pathogenesis of VZV.
Quantitative trait loci mapping for meat quality traits in swine chromosome 6 (Mapeamento de locos de características quantitativas no cromossomo 6 de suínos, associados à qualidade da carne) (2005)

The current study was carried out to perform QTL mapping on swine chromosome 6 (SSC6) associated to meat quality traits. The F2 population was produced by outbreed crossing using two native Brazilian breed Piau boars and 18 commercial sows. A total of 557 F2 animals were genotyped for 13 microsatellite markers. The traits evaluated on the F2 population were: pH measured 45 minutes and 24 hours post mortem (pH 45, pH24, respectively), drip loss (DL), cooking loss (CL), total loss (TL), intramuscular fat content (IMF), objective tenderness (OT), lightness (L), redness (A), yellowness (B), hue angle (h) and chrome (c). Data were analyzed by multiple regression developed for analysis of outbreed line crosses, using the QTL Express Software. Significant QTL were detected for pH45 and DL traits, and suggestive QTL for DL. QTL were not found for other traits. The pH45 and DL traits may be under the influence of one gene or a gene group located at about 76, 88 and 97cM. More markers should be included in the regions where F-value peaks and suggestive QTL for the DL trait were detected to ascertain whether they are real QTL.
QUARK HELICITY FLIP AND THE TRANSVERSE SPIN DEPENDENCE OF INCLUSIVE DIS (2008)

Inclusive DIS with unpolarized beam exhibits a subtle dependence on the transverse target spin, arising from the interference of one-photon and two-photon exchange amplitudes in the cross section. We argue that this observable probes mainly the quark helicity-flip amplitudes induced by the non-perturbative vacuum structure of QCD (spontaneous chiral symmetry breaking). This conjecture is based on (a) the absence of significant Sudakov suppression of the helicity-flip process if soft gluon emission in the quark subprocess is limited by the chiral symmetry-breaking scale mu_chiral^2 >> Lambda_QCD^2; (b) the expectation that the quark helicity-conserving twist-3 contribution is small. The normal target spin asymmetry is estimated to be of the order 10^{-4} in the kinematics of the planned Jefferson Lab Hall A experiment.
Multimodal interfaces: Challenges and perspectives (2009)

The development of interfaces has been a technology-driven process. However, the newly developed multimodal interfaces are using recognition-based technologies that must interpret human-speech, gesture, gaze, movement patterns, and other behavioral c
Stem Cells for Retinal Degenerative Disorders (2005)

Many systemic and eye-specific genetic disorders are accompanied by retinal degenerations that lead to blindness. In some of these diseases retinal degeneration occurs early in life and is quite rapid, whereas in other disorders, retinal degeneration starts later and progresses very slowly. At present, no therapies are available to patients for preventing or reversing the retinal degeneration that occurs in these diseases. Implantation of neural progenitor cells into the eye may be a means by which to retard or even reverse degeneration of the retina. To evaluate the potential of neural precursor cell implantation for treating retinal degenerative disorders, neuralized mouse embryonic stem cells from green fluorescent protein (GFP) transgenic mice were administered intravitreally to normal mice, mice with early retinal degeneration, and mice with slowly progressing retinal degeneration. In normal mice, the donor cells remained in the vitreous cavity and did not associate with the host retina. In mice with early retinal degeneration, implantation of the neural precursors was performed after the degeneration was almost complete. In these animals, the donor cells primarily associated closely with the inner surface of the retina, although a small fraction of donor cells did integrate into the host retina. Donor cells implanted in mice with slowly progressing retinal degeneration also associated with the inner retinal surface, but many more of the cells integrated into the retina. These findings indicate the importance of host tissue-donor cell interactions in determining the fate of implanted neural precursor cells. These interactions will be a major consideration when devising strategies for using cell implantation therapies for neurodegenerative disorders.
Antifungal Activity of 3′-Deoxyadenosine (Cordycepin) (1998)

The antifungal activity of the nucleoside analog 3'-deoxyadenosine (cordycepin) was studied in a murine model of invasive candidiasis. When protected from deamination by either deoxycoformycin or coformycin, both of which are adenosine deaminase inhibitors, cordycepin exhibited potent antifungal efficacy, as demonstrated by prolongation of survival and a decrease in CFU in the kidneys of mice treated with cordycepin plus an adenosine deaminase inhibitor. The antifungal effect was seen with three different Candida isolates: Candida albicans 64, a relatively fluconazole-resistant clinical isolate of C. albicans (MIC, 16 micrograms/ml), and the fluconazole-resistant Candida krusei. Cordycepin and related compounds may provide another avenue for the discovery of clinically useful antifungal drugs.
Organometallic vapor phase epitaxial growth of AlGaInP (1985)

AlxGayIn1−x−yP with x+y=0.51, lattice matched to the GaAs substrate, has been grown by organometallic vapor phase epitaxy. The simple, horizontal, IR heated system operates at atmospheric pressure using the reactants TMAl, TMGa, TMIn, PH3, and H2. Alloys giving room temperature, band edge photoluminescence (PL) have been grown in the temperature range 625–780 °C. Emission wavelengths as short as 5820 Å (2.13 eV) are reported. High growth temperatures are found to give layers with the best surface morphology and PL intensity. The use of high temperatures is especially important for high Al content alloys. PL at x=0.2 is obtained only for temperatures above 740 °C.
Substitution of Specific Cysteine Residues in the E1 Glycoprotein of Classical Swine Fever Virus Strain Brescia Affects Formation of E1-E2 Heterodimers and Alters Virulence in Swine (2011)

E1, along with E(rns) and E2, is one of the three envelope glycoproteins of classical swine fever virus (CSFV). E1 and E2 are anchored to the virus envelope at their carboxyl termini, and E(rns) loosely associates with the viral envelope. In infected cells, E2 forms homodimers and heterodimers with E1 mediated by disulfide bridges between cysteine residues. The E1 protein of CSFV strain Brescia contains six cysteine residues at positions 5, 20, 24, 94, 123, and 171. The role of these residues in the formation of E1-E2 heterodimers and their effect on CSFV viability in vitro and in vivo remain unclear. Here we observed that recombinant viruses harboring individual cysteine-to-serine substitutions within the E1 envelope protein still have formation of E1-E2 heterodimers which are functional in terms of allowing efficient virus progeny yields in infected primary swine cells. Additionally, these single cysteine mutant viruses were virulent in infected swine. However, a double mutant harboring Cys24Ser and Cys94Ser substitutions within the E1 protein altered formation of E1-E2 heterodimers in infected cells. This recombinant virus, E1ΔCys24/94v, showed delayed growth kinetics in primary swine macrophage cultures and was attenuated in swine. Furthermore, despite the observed diminished growth in vitro, infection with E1ΔCys24/94v protected swine from challenge with virulent CSFV strain Brescia at 3 and 28 days postinfection.
Non-destructive Determination of Fluorine with Be-D Neutron Activation Analysis Using Gold as Internal Standard (1971)

種々の化合物中のフッ素含量の定量に対して, 迅速かつ非破壊的な方法が要求されている。時間のかからない容易な分析方法として, フッ素定量に速中性子放射化分析法が考えられるようになった。本研究では, 19F(n,α)16N 反応によって生成する短半減期同位体 16N を用いる方法について検討した。この反応を用いる有利な点は, 他の生成核種の妨害を受けないような高エネルギーの γ線を 16N が出すことである。160(n,p)16N 反応による妨害は, 16O の (n,p) 反応のしきい値以下のエネルギーの中性子を用いて除いた。照射は 2MeV の重水素をベリリウムターゲットに衝撃して得られる 1～6MeV のエネルギーを有するベリリウム-重水素中性子で行なった。また, 分析条件の変化, 特に中性子束の変化による精度の低下をさけるために, 金を内部標準として用いた。197Au(n,n')197mAu 反応で生ずる 197mAu は, 19F(n,α)16N からの 16 と半減期が等しいことから, 前者の放射能で後者の放射能が規格化された。結果として, 60～800mg のフッ素に対して, 平均相対誤差 2. 1% で直線の検量線が得られた。この方法は中性子放射化分析によるフッ素定量法として有用であろう。
MiR-328 targeting PIM-1 inhibits proliferation and migration of pulmonary arterial smooth muscle cells in PDGFBB signaling pathway (2016)

MicroRNAs (miRNAs) have been recognized to mediate PDGF-induced cell dysregulation, but their exact functions remain to be elucidated. By using a sensitive S-Poly(T) Plus qRT-PCR method, the expression profiling of 1,078 miRNAs were investigated in pulmonary artery smooth muscle cells (PASMCs) with or without PDGFBB stimulation. MiR-328 was found as a prominent down-regulated miRNA, displaying a specific dose- and time-dependent downregulation upon PDGFBB exposure. Functional analyses revealed that miR-328 could inhibit PASMCs proliferation and migration both with and without PDGFBB treatment. The Ser/Thr-protein kinase-1 (PIM-1) was identified as a direct target of miR-328, and functionally confirmed by a rescue experiment. In addition, the decrease of miR-328 by PDGFBB might be due to the increased expression of DNA methylation transferase 1 (DNMT1) and DNA methylation. Finally, serum miR-328 level was downregulated in PAH patients associated with congenital heart disease (CHD- PAH). Overall, this study provides critical insight into fundamental regulatory mechanism of miR-328 in PDGFBB-activited PASMCs via targeting PIM- 1, and implies the potential of serum miR-328 level as a circulating biomarker for CHD- PAH diagnosis.
Synthesis of 2,5-Anhydro-3,4,6-tri-O-benzyl-<scp>l</scp>-talose Dimethylacetal via 2,5-Anhydro-3,6-di-O-tosyl-<scp>l</scp>-idose Dimethylacetal (1972)

Journal Article Synthesis of 2,5-Anhydro-3,4,6-tri-O-benzyl-l-talose Dimethylacetal via 2,5-Anhydro-3,6-di-O-tosyl-l-idose Dimethylacetal Get access Tomoya Ogawa, Tomoya Ogawa The Institute of Physical and Chemical Research, Wako-shi, Saitama Japan Search for other works by this author on: Oxford Academic Google Scholar Masanao Matsui, Masanao Matsui The Institute of Physical and Chemical Research, Wako-shi, Saitama Japan Search for other works by this author on: Oxford Academic Google Scholar Hiroshi Ohrui, Hiroshi Ohrui The Institute of Physical and Chemical Research, Wako-shi, Saitama Japan Search for other works by this author on: Oxford Academic Google Scholar Hiroyoshi Kuzuhara, Hiroyoshi Kuzuhara The Institute of Physical and Chemical Research, Wako-shi, Saitama Japan Search for other works by this author on: Oxford Academic Google Scholar Sakae Emoto Sakae Emoto The Institute of Physical and Chemical Research, Wako-shi, Saitama Japan Search for other works by this author on: Oxford Academic Google Scholar Agricultural and Biological Chemistry, Volume 36, Issue 9, 1 September 1972, Pages 1655–1657, https://doi.org/10.1080/00021369.1972.10860456 Published: 01 September 1972 Article history Received: 05 June 1972 Published: 01 September 1972
Preparation of high-purity Tl-based ‘‘1223’’ superconductor phase by modified Pechini process in water solution (1991)

Because of the mixed metal valance state of thallium in a Tl-based superconductor, a nearly single ‘‘1223’’ phase can be readily prepared by a modified Pechini method (US Patent 3 330 697). Tl2O3 and other metal nitrates are dissolved in an aqueous solution plus a certain amount of oxalic acid for chelating the metal cations. The desired phase shows zero resistance at 114 K and the phase purity is identified by x-ray diffraction. Characteristics of superconductivity also are evidenced by the Meissner effect. The preparation technique is considered valuable to purify multiphase superconductors for mass production.
Alterations in Humoral Immune Response to Bovine Leukaemia Virus Antigens in Cattle with Lymphoma (1988)

Sera collected from cattle with enzootic bovine lymphoma (EBL) were compared to sera from clinically normal bovine leukaemia virus (BLV)-infected cattle for immunoglobulin concentration and for antibodies detecting BLV proteins tested using three different viral isolates. Monoclonal antibodies to bovine immunoglobulin isotypes were used in Western blot analysis to identify isotype reactivity to specific viral antigens. IgG titres to BLV were determined by ELISA. Serum immunoglobulin (G1, G2 and M) concentrations were assessed by radial immunodiffusion. Although EBL was associated with reduced total immunoglobulin production, sera from cattle with EBL had significantly (P less than 0.001) higher specific IgG titres and produced antibodies against a greater and more varied number of BLV proteins than did sera from clinically normal BLV-infected cattle. Variations were consistent within groups of cattle and did not depend on the viral isolate used.
Gestion informatisée des stupéfiants à l'hôpital à l'aide du logiciel Morphée (2003)

La gestion des medicaments dits stupefiants est regie par une reglementation tres precise et rigoureuse. Il nous a semble que l'informatique pourrait apporter une aide certaine au suivi de ces medicaments, c'est pourquoi nous avons developpe un logiciel permettant une gestion des mouvements des stocks integrant les dotations des services de soins et les ordonnances nominatives, ainsi qu'une gestion des destructions et offrant des etats utiles a des analyses ponctuelles. Le surcroit de travail genere par la saisie informatique a pu etre compense par la suppression des ecritures obligatoires grâce a l'informatisation des documents papier (releve de dotation, releve nominatif de dispensation, ordonnancier manuel, etat des stocks) et la revision des dotations des services grandement facilitee. Le gain de qualite et de tracabilite a ete manifeste et malgre une constante augmentation des dispensations de stupefiants, le temps passe a leur gestion a pu rester a peu pres stable.
Assessment of the ionized EL2 fraction in semi-insulating GaAs (1989)

Both optical and electrical methods were used to provide separate evaluations of the fraction Pi of EL2 defect donors which have lost an electron. The semi-insulating GaAs which permitted these assessments had a large enough fraction of the EL2 compensated (by CAs acceptors) to make this a sensitive test. Room-temperature Hall effect data, analyzed with an ambipolar correction, indicated that Pi ≂0.34 in material from a vertical-zone grown crystal, while near-infrared optical absorption could be modeled on a superposition of EL2 photoionization and photoneutralization to yield Pi ≂0.35 in the same crystal. The presence of compensating CAs acceptors was verified by local mode vibrational absorption.
Two-dimensional map of human brain proteins (1999)

Samples of human brain from the parietal cortex lobe were analyzed by two-dimensional gel electrophoresis, using immobilized pH gradient strips covering the various pH regions. The protein spots were visualized with colloidal Coomassie blue stain and identified by matrix-assisted laser desorption/ionization mass spectrometry. Approximately 400 spots were identified, corresponding to 180 different brain proteins. The list of identified proteins includes a large number of structural proteins and of enzymes or enzyme subunits with various catalytic activities. The majority of proteins are localized in the cytoplasma and in mitochondria. The two-dimensional map may be useful as a reference database to study changes in the protein level caused by various disorders, such as Alzheimer's disease, major depression and schizophrenia.
Splenectomy in Mediterranean Anemia (1956)

New York, N. Y. Department of Surgery, Columbia University College of Physicians and Surgeons, and the Surgical Services, Babies and Presbyterian Hospitals
Genetic control of the immune response to collagen. II. Antibody responses produced in fetal liver restored radiation chimeras and thymus reconstituted F1 hybrid nude mice. (1979)

The level of antibody produced in response to calf skin collagen in mice is influenced by genes which are closely linked to the I region of the H-2 major histocompatibility complex. This influence is shown to be expressed during lymphoid maturation by testing the antibody responsiveness to collagen in two types of chimeric mice. First, high responder and low responder parental strain mice were lethally irradiated and restored with fetal liver cells from (high X low responder) F1 mice. These F1 leads to parent chimeras exhibited an immune response phenotype characteristic of the irradiated parental strain animals, establishing that H-2 determinants of the host affect antigen responsiveness. Second, (high X low responder) F1 congenitally athymic (nude) mice were restored with fetal thymus transplants from either high or low responder parental strain mice. After a period of maturation these mice were shown to be competent for a T-dependent IgG response to SRBC. The responsiveness to collagen in these mice was characteristic of the parental strain thymus donors, indicating that the expression of H-2 determinants in thymic tissue during lymphoid maturation influences the antibody response phenotype expressed by mice.
Surface Modification of Stainless Steel by Electrical Discharge Machining. (1993)

A commercial SUS304 stainless steel was machined by EDM with a sialon electrode. The machined surface changed from the machining to the surface modification layer on the someproper machining conditions. Theeffect of the following factors to form the surface layer was investigated: Electrode polarity, work atmosphereand the working condition of the peak current, pulse duration and duty factor. Underthe suitable machining conditions, the EDMed surface was covered with the alloyed layer, which consisted of the electrode and work piece components. The surface modified layer improved the corrosion and wear resistance.
A New Two-Step Stereospecific Synthesis of Glycidic Spiroacetals (1990)

ABSTRACT The spiroacetal moiety has received much attention in recent years owing to its occurence in several biologically important natural products.1 In that field, the antibiotics avermectins,2 milbemycins3 and papulacandins4 are of particular interest to us because a carbohydrate precursor could be employed for their syntheses.5-7 other glycidic spiroacetals were obtained by photocarbocyclization of 2-carbophenyl-β-D-glucopyranosides.8
Noncataleptic neuroleptic agents: 2-(4-(2-(2-Chloro-10,11-dihydrodibenzo[b,f]thiepin-10-yloxy)ethyl)piperazine-1-yl)ethanol and some related compounds (1988)

10-(2-Bromoethoxy)-2-chloro-10,11-dihydrodibenzo[ b,f ]thiepin ( X ), prepared by two methods, was subjected to substitution reactions with 2-(1-piperazinyl)ethanol, 3-(1-piperazinyl)propanol, 1-methylpiperazine, 3-(1-piperazinyl)propionamide, piperazine, and 1-(ethoxycarbonyl)piperazine and gave the title compounds II-VII . The alcohol II was esterified by treatment with acid chlorides to compounds VIII and IX . Compounds II, V , and VIII proved to be noncataleptic neuroleptic agents and II (clopithepin, VÚFB-17 076) was selected for preclinical studies.
Motion Generation for Human-Robot Cooperation considering Range of Joint Movement (2006)

We have proposed a real-time self-collision avoidance motion generation method for the manipulator of the robot used for human-robot cooperation. In this method, we represent the robots' body by using elastic elements referred to as "RoBE (representation of body by elastic elements)". The self-collision avoidance could be realized based on a virtual reaction force generated by the contacts between the elastic elements before the actual self-collision of the robot. In this paper, we expand this method to control not only robots' manipulator, but also its mobile base. Furthermore, we focus on the range of the joint movement of the robot, and propose the self-collision avoidance motion generation method considering it. Because of these, the self-collision motions which could deal with task/environmental constraints could be generated on the robot cooperating with a human. The proposed method is implemented in the planar 4-DOF mobile manipulator, and computer simulations are done for illustrating the validity of it